Gene Expression Literature Summary

• Symbol: Ptprz1
• Name: protein tyrosine phosphatase receptor type Z, polypeptide 1
• ID: MGI:97816

41 matching records from 41 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8.5	E9.5	E10.5	E11.5	E12.5	E13	E13.5	E14.5	E15	E15.5	E16	E16.5	E17.5	E18	E18.5	E20	E	P
Immunohistochemistry (section)		1	2	3	3	1	8	2		9		1	2	1	3	1		6
In situ RNA (section)				3	2	1	6	4		8		2	2	1	2	1	1	8
Immunohistochemistry (whole mount)							1
In situ RNA (whole mount)			1	1	1
In situ reporter (knock in)	1				1													1
Northern blot									1									3
Western blot					1	1	1		2	2	1			2	1			6
RT-PCR					1		2	1		3	1		1		1			4
cDNA clones							1											2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ptprz1  protein tyrosine phosphatase receptor type Z, polypeptide 1   (Synonyms: DSD-1-PG, phosphacan, PTPbeta, Ptprz, Ptpz, PTPzeta, Rptpbeta, RPTPz)
Results	Reference
3	J:99698 Abramova N, Charniga C, Goderie SK, Temple S, Stage-specific changes in gene expression in acutely isolated mouse CNS progenitor cells. Dev Biol. 2005 Jul 15;283(2):269-81
2*	J:49909 Ba-Charvet KT, von Boxberg Y, Guazzi S, Boncinelli E, Godement P, A potential role for the OTX2 homeoprotein in creating early 'highways' for axon extension in the rostral brain. Development. 1998 Nov;125(21):4273-82
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
7*	J:187511 Besser M, Jagatheaswaran M, Reinhard J, Schaffelke P, Faissner A, Tenascin C regulates proliferation and differentiation processes during embryonic retinogenesis and modulates the de-differentiation capacity of Muller glia by influencing growth factor responsiveness and the extracellular matrix compartment. Dev Biol. 2012 Sep 15;369(2):163-76
1*	J:100830 Bischof JM, Wevrick R, Genome-wide analysis of gene transcription in the hypothalamus. Physiol Genomics. 2005 Jul 14;22(2):191-6
1	J:40497 Blackshear PJ, Silver J, Nairn AC, Sulik KK, Squier MV, Stumpo DJ , Tuttle JS, Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice. Exp Neurol. 1997 May;145(1):46-61
7*	J:63083 Clarris HJ, Rauch U, Key B, Dynamic spatiotemporal expression patterns of neurocan and phosphacan indicate diverse roles in the developing and adult mouse olfactory system. J Comp Neurol. 2000 Jul 17;423(1):99-111
4	J:192518 Dwyer CA, Baker E, Hu H, Matthews RT, RPTPzeta/phosphacan is abnormally glycosylated in a model of muscle-eye-brain disease lacking functional POMGnT1. Neuroscience. 2012 Sep 18;220:47-61
6*	J:84104 Garwood J, Heck N, Reichardt F, Faissner A, Phosphacan short isoform, a novel non-proteoglycan variant of phosphacan/receptor protein tyrosine phosphatase-beta, interacts with neuronal receptors and promotes neurite outgrowth. J Biol Chem. 2003 Jun 27;278(26):24164-73
6*	J:54926 Garwood J, Schnadelbach O, Clement A, Schutte K, Bach A, Faissner A, DSD-1-proteoglycan is the mouse homolog of phosphacan and displays opposing effects on neurite outgrowth dependent on neuronal lineage. J Neurosci. 1999 May 15;19(10):3888-99
3*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
2*	J:115165 Hecht J, Seitz V, Urban M, Wagner F, Robinson PN, Stiege A, Dieterich C, Kornak U, Wilkening U, Brieske N, Zwingman C, Kidess A, Stricker S, Mundlos S, Detection of novel skeletogenesis target genes by comprehensive analysis of a Runx2(-/-) mouse model. Gene Expr Patterns. 2007 Jan;7(1-2):102-12
2	J:259186 Heng X, Guo Q, Leung AW, Li JY, Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6:e23253
1	J:83512 Hikake T, Mori T, Iseki K, Hagino S, Zhang Y, Takagi H, Yokoya S, Wanaka A, Comparison of expression patterns between CREB family transcription factor OASIS and proteoglycan core protein genes during murine tooth development. Anat Embryol (Berl). 2003 Apr;206(5):373-80
1	J:351385 Kaneko N, Hirai K, Oshima M, Yura K, Hattori M, Maeda N, Ohtaka-Maruyama C, ADAMTS2 promotes radial migration by activating TGF-beta signaling in the developing neocortex. EMBO Rep. 2024 Jul;25(7):3090-3115
6*	J:199197 Karus M, Hennen E, Safina D, Klausmeyer A, Wiese S, Faissner A, Differential expression of micro-heterogeneous LewisX-type glycans in the stem cell compartment of the developing mouse spinal cord. Neurochem Res. 2013 Jun;38(6):1285-94
5*	J:187432 Karus M, Samtleben S, Busse C, Tsai T, Dietzel ID, Faissner A, Wiese S, Normal sulfation levels regulate spinal cord neural precursor cell proliferation and differentiation. Neural Dev. 2012;7(1):20
9*	J:135623 Klausmeyer A, Garwood J, Faissner A, Differential expression of phosphacan/RPTPbeta isoforms in the developing mouse visual system. J Comp Neurol. 2007 Oct 20;504(6):659-79
2*	J:321499 Lee DR, Rhodes C, Mitra A, Zhang Y, Maric D, Dale RK, Petros TJ, Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain. Elife. 2022 Feb 17;11:e71864
3*	J:93585 Leung KM, Margolis RU, Chan SO, Expression of phosphacan and neurocan during early development of mouse retinofugal pathway. Brain Res Dev Brain Res. 2004 Aug 18;152(1):1-10
3*	J:4968 Levy JB, Canoll PD, Silvennoinen O, Barnea G, Morse B, Honegger AM, Huang JT, Cannizzaro LA, Park SH, Druck T, Huebner K, Sap J, Ehrlich M, Musacchio JM, Schlessinger J, The cloning of a receptor-type protein tyrosine phosphatase expressed in the central nervous system. J Biol Chem. 1993 May 15;268(14):10573-81
1	J:267913 Liu WA, Chen S, Li Z, Lee CH, Mirzaa G, Dobyns WB, Ross ME, Zhang J, Shi SH, PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia. Genes Dev. 2018 Jun 1;32(11-12):763-780
1*	J:270210 Loo L, Simon JM, Xing L, McCoy ES, Niehaus JK, Guo J, Anton ES, Zylka MJ, Single-cell transcriptomic analysis of mouse neocortical development. Nat Commun. 2019 Jan 11;10(1):134
1	J:175548 Maddala R, Skiba NP, Lalane R 3rd, Sherman DL, Brophy PJ, Rao PV, Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers. Dev Biol. 2011 Sep 1;357(1):179-90
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1	J:261809 Mayer C, Hafemeister C, Bandler RC, Machold R, Batista Brito R, Jaglin X, Allaway K, Butler A, Fishell G, Satija R, Developmental diversification of cortical inhibitory interneurons. Nature. 2018 Mar 22;555(7697):457-462
3*	J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
1*	J:205051 Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, Sestan N, Gage FH, Lein ES, Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44
5*	J:219223 Nagalakshmi VK, Lindner V, Wessels A, Yu J, microRNA-dependent temporal gene expression in the ureteric bud epithelium during mammalian kidney development. Dev Dyn. 2015 Mar;244(3):444-56
1	J:282572 Nakagawa N, Plestant C, Yabuno-Nakagawa K, Li J, Lee J, Huang CW, Lee A, Krupa O, Adhikari A, Thompson S, Rhynes T, Arevalo V, Stein JL, Molnar Z, Badache A, Anton ES, Memo1-Mediated Tiling of Radial Glial Cells Facilitates Cerebral Cortical Development. Neuron. 2019 Sep 4;103(5):836-852.e5
2	J:87756 Ohyama K, Ikeda E, Kawamura K, Maeda N, Noda M, Receptor-like protein tyrosine phosphatase zeta/RPTP beta is expressed on tangentially aligned neurons in early mouse neocortex. Brain Res Dev Brain Res. 2004 Jan 31;148(1):121-7
4*	J:48402 Ohyama K, Kawano H, Asou H, Fukuda T, Oohira A, Uyemura K, Kawamura K, Coordinate expression of L1 and 6B4 proteoglycan/phosphacan is correlated with the migration of mesencephalic dopaminergic neurons in mice. Brain Res Dev Brain Res. 1998 May 15;107(2):219-26
5*	J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584
1	J:156199 Robel S, Mori T, Zoubaa S, Schlegel J, Sirko S, Faissner A, Goebbels S, Dimou L, Gotz M, Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis. Glia. 2009 Nov 15;57(15):1630-47
3	J:314173 Schaberg E, Theocharidis U, May M, Lessmann K, Schroeder T, Faissner A, Sulfation of Glycosaminoglycans Modulates the Cell Cycle of Embryonic Mouse Spinal Cord Neural Stem Cells. Front Cell Dev Biol. 2021;9:643060
1	J:293277 Shao W, Yang J, He M, Yu XY, Lee CH, Yang Z, Joyner AL, Anderson KV, Zhang J, Tsou MB, Shi H, Shi SH, Centrosome anchoring regulates progenitor properties and cortical formation. Nature. 2020 Apr;580(7801):106-112
4*	J:85827 Shintani T, Watanabe E, Maeda N, Noda M, Neurons as well as astrocytes express proteoglycan-type protein tyrosine phosphatase zeta/RPTPbeta: analysis of mice in which the PTPzeta/RPTPbeta gene was replaced with the LacZ gene. Neurosci Lett. 1998 May 15;247(2-3):135-8
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
4	J:151326 Treloar HB, Ray A, Dinglasan LA, Schachner M, Greer CA, Tenascin-C is an inhibitory boundary molecule in the developing olfactory bulb. J Neurosci. 2009 Jul 29;29(30):9405-16
1*	J:281175 Yorgan TA, Peters S, Amling M, Schinke T, Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling. Bone. 2019 Oct;127:155-163
7	J:356745 Yuzwa SA, Borrett MJ, Innes BT, Voronova A, Ketela T, Kaplan DR, Bader GD, Miller FD, Developmental Emergence of Adult Neural Stem Cells as Revealed by Single-Cell Transcriptional Profiling. Cell Rep. 2017 Dec 26;21(13):3970-3986