Gene Expression Literature Summary

• Symbol: Rag2
• Name: recombination activating gene 2
• ID: MGI:97849

14 matching records from 14 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E1.5	E2	E4	E8.5	E9.5	E10.5	E11.5	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19.5	E20	E	P
In situ RNA (section)																										1
Northern blot																		1								1
Western blot												1														1
RT-PCR	1	1	1	1	1	1	2	3	3	2	1	2	1	3	1	3	1	2	1	2	1	2	1	1	3	7

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Rag2  recombination activating gene 2   (Synonyms: Rag-2)
Results	Reference
2	J:287171 Alvarez-Lindo N, Baleriola J, de Los Rios V, Suarez T, de la Rosa EJ, RAG-2 deficiency results in fewer phosphorylated histone H2AX foci, but increased retinal ganglion cell death and altered axonal growth. Sci Rep. 2019 Dec 6;9(1):18486
1	J:28600 Boehm T, Gonzalez-Sarmiento R, Kennedy M, Rabbitts TH, A simple technique for generating probes for RNA in situ hybridization: an adjunct to genome mapping exemplified by the RAG-1/RAG-2 gene cluster. Proc Natl Acad Sci U S A. 1991 May 1;88(9):3927-31
3	J:84781 Chun JJ, Schatz DG, Oettinger MA, Jaenisch R, Baltimore D, The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system. Cell. 1991 Jan 11;64(1):189-200
7	J:80541 de Andres B, Gonzalo P, Minguet S, Martinez-Marin JA, Soro PG, Marcos MA, Gaspar ML, The first 3 days of B-cell development in the mouse embryo. Blood. 2002 Dec 1;100(12):4074-81
1*	J:74716 DeKoter RP, Lee HJ, Singh H, PU.1 Regulates Expression of the Interleukin-7 Receptor in Lymphoid Progenitors. Immunity. 2002 Feb;16(2):297-309
6*	J:53093 Haks MC, Oosterwegel MA, Blom B, Spits HM, Kruisbeek AM, Cell-fate decisions in early T cell development: regulation by cytokine receptors and the pre-TCR. Semin Immunol. 1999 Feb;11(1):23-37
6*	J:32231 Hayakawa S, Tochigi M, Chishima F, Shiraishi H, Takahashi N, Watanabe K, Fujii KT, Satoh K, Expression of the recombinase-activating gene (RAG-1) in murine early embryogenesis. Immunol Cell Biol. 1996 Feb;74(1):52-6
2	J:18908 Hozumi K, Kobori A, Sato T, Nozaki H, Nishikawa S, Nishimura T, Habu S, Pro-T cells in fetal thymus express c-kit and RAG-2 but do not rearrange the gene encoding the T cell receptor beta chain. Eur J Immunol. 1994 Jun;24(6):1339-44
1	J:279141 Masuda K, Kubagawa H, Ikawa T, Chen CC, Kakugawa K, Hattori M, Kageyama R, Cooper MD, Minato N, Katsura Y, Kawamoto H, Prethymic T-cell development defined by the expression of paired immunoglobulin-like receptors. EMBO J. 2005 Dec 7;24(23):4052-60
11*	J:49918 Murray AM, Simm B, Beagley KW, Cytokine gene expression in murine fetal intestine: potential for extrathymic T cell development. Cytokine. 1998 May;10(5):337-45
4*	J:106178 Rampon C, Huber P, Multilineage hematopoietic progenitor activity generated autonomously in the mouse yolk sac: analysis using angiogenesis-defective embryos. Int J Dev Biol. 2003 May;47(4):273-80
7	J:20032 Schlissel MS, Morrow T, Ig heavy chain protein controls B cell development by regulating germ-line transcription and retargeting V(D)J recombination. J Immunol. 1994 Aug 15;153(4):1645-57
1	J:108342 Terszowski G, Muller SM, Bleul CC, Blum C, Schirmbeck R, Reimann J, Pasquier LD, Amagai T, Boehm T, Rodewald HR, Evidence for a functional second thymus in mice. Science. 2006 Apr 14;312(5771):284-7
1	J:296348 Yamamoto S, Muramatsu M, Azuma E, Ikutani M, Nagai Y, Sagara H, Koo BN, Kita S, O'Donnell E, Osawa T, Takahashi H, Takano KI, Dohmoto M, Sugimori M, Usui I, Watanabe Y, Hatakeyama N, Iwamoto T, Komuro I, Takatsu K, Tobe K, Niida S, Matsuda N, Shibuya M, Sasahara M, A subset of cerebrovascular pericytes originates from mature macrophages in the very early phase of vascular development in CNS. Sci Rep. 2017 Jun 20;7(1):3855