Gene Expression Literature Summary

• Symbol: Rap1a
• Name: RAS-related protein 1a
• ID: MGI:97852

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E2	E3.5	E9.5	E10.5	E11	E11.5	E12.5	E13.5	E16	E17	E17.5	E	P
Immunohistochemistry (section)					1	1	1				1	1		2
In situ RNA (section)														1
In situ reporter (knock in)								1
Western blot				1	1		1	1	1	1		1		6
RT-PCR	1	1	1									1		3
cDNA clones													1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Rap1a  RAS-related protein 1a   (Synonyms: Krev-1, Rap1)
Results	Reference
5*	J:316204 Chen Z, Xu N, Chong D, Guan S, Jiang C, Yang Z, Li C, Geranylgeranyl pyrophosphate synthase facilitates the organization of cardiomyocytes during mid-gestation through modulating protein geranylgeranylation in mouse heart. Cardiovasc Res. 2018 Jun 1;114(7):965-978
1	J:333325 Cheng Q, Wu J, Xia Y, Cheng Q, Zhao Y, Zhu P, Zhang W, Zhang S, Zhang L, Yuan Y, Li C, Chen G, Xue B, Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation. Mol Brain. 2023 Feb 13;16(1):24
2*	J:144145 Duchniewicz M, Zemojtel T, Kolanczyk M, Grossmann S, Scheele JS, Zwartkruis FJ, Rap1A-deficient T and B cells show impaired integrin-mediated cell adhesion. Mol Cell Biol. 2006 Jan;26(2):643-53
1	J:262823 Kasowitz SD, Ma J, Anderson SJ, Leu NA, Xu Y, Gregory BD, Schultz RM, Wang PJ, Nuclear m6A reader YTHDC1 regulates alternative polyadenylation and splicing during mouse oocyte development. PLoS Genet. 2018 May;14(5):e1007412
1	J:178484 Maddala R, Chauhan BK, Walker C, Zheng Y, Robinson ML, Lang RA, Rao PV, Rac1 GTPase-deficient mouse lens exhibits defects in shape, suture formation, fiber cell migration and survival. Dev Biol. 2011 Dec 1;360(1):30-43
7*	J:226036 Maddala R, Nagendran T, Lang RA, Morozov A, Rao PV, Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis. Dev Biol. 2015 Oct 1;406(1):74-91
1*	J:242457 Qiao S, Homayouni R, Dab2IP Regulates Neuronal Positioning, Rap1 Activity and Integrin Signaling in the Developing Cortex. Dev Neurosci. 2015;37(2):131-41
2	J:241040 Shah B, Lutter D, Tsytsyura Y, Glyvuk N, Sakakibara A, Klingauf J, Puschel AW, Rap1 GTPases Are Master Regulators of Neural Cell Polarity in the Developing Neocortex. Cereb Cortex. 2017 Feb 01;27(2):1253-1269
1	J:269939 Stefanini L, Lee RH, Paul DS, O'Shaughnessy EC, Ghalloussi D, Jones CI, Boulaftali Y, Poe KO, Piatt R, Kechele DO, Caron KM, Hahn KM, Gibbins JM, Bergmeier W, Functional redundancy between RAP1 isoforms in murine platelet production and function. Blood. 2018 Nov 1;132(18):1951-1962
1	J:221899 Stefanini L, Paul DS, Robledo RF, Chan ER, Getz TM, Campbell RA, Kechele DO, Casari C, Piatt R, Caron KM, Mackman N, Weyrich AS, Parrott MC, Boulaftali Y, Adams MD, Peters LL, Bergmeier W, RASA3 is a critical inhibitor of RAP1-dependent platelet activation. J Clin Invest. 2015 Apr;125(4):1419-32
5*	J:16710 Temeles GL, Ram PT, Rothstein JL, Schultz RM, Expression patterns of novel genes during mouse preimplantation embryogenesis. Mol Reprod Dev. 1994 Feb;37(2):121-9
1	J:229358 Teo ZL, McQueen-Miscamble L, Turner K, Martinez G, Madakashira B, Dedhar S, Robinson ML, de Iongh RU, Integrin linked kinase (ILK) is required for lens epithelial cell survival, proliferation and differentiation. Exp Eye Res. 2014 Apr;121:130-42
2	J:172908 Traver S, Bidot C, Spassky N, Baltauss T, De Tand MF, Thomas JL, Zalc B, Janoueix-Lerosey I, Gunzburg JD, RGS14 is a novel Rap effector that preferentially regulates the GTPase activity of galphao. Biochem J. 2000 Aug 15;350 Pt 1:19-29