Gene Expression Literature Summary

• Symbol: Ren2
• Name: renin 2 tandem duplication of Ren1
• ID: MGI:97899

13 matching records from 13 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E10.5	E11	E11.5	E12.5	E13.5	E14.5	E15.5	E16	E16.5	E17.5	E18.5	E	P
Immunohistochemistry (section)						1	1	1	1	1	4	1	4
In situ RNA (section)			1		1	2							1
In situ RNA (whole mount)					1
Northern blot					1		1						1
Western blot													2
RT-PCR	1	1	1	1	1	1	1		1	1	2		5
cDNA clones					1
Primer Extension													1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Ren2  renin 2 tandem duplication of Ren1   (Synonyms: Ren, Ren-2, Ren-B, Rn-2, Rnr)
Results	Reference
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
4	J:333395 Gunawardhana KL, Hong L, Rugira T, Uebbing S, Kucharczak J, Mehta S, Karunamuni DR, Cabera-Mendoza B, Gandotra N, Scharfe C, Polimanti R, Noonan JP, Mani A, A systems biology approach identifies the role of dysregulated PRDM6 in the development of hypertension. J Clin Invest. 2023 Feb 15;133(4)
2*	J:175301 Kitazawa T, Sato T, Nishiyama K, Asai R, Arima Y, Uchijima Y, Kurihara Y, Kurihara H, Identification and developmental analysis of endothelin receptor type-A expressing cells in the mouse kidney. Gene Expr Patterns. 2011 Oct;11(7):371-7
1*	J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735
1	J:50064 Lindahl P, Hellstrom M, Kalen M, Karlsson L, Pekny M, Pekna M, Soriano P, Betsholtz C, Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli. Development. 1998 Sep;125(17):3313-22
4	J:153990 Machura K, Steppan D, Neubauer B, Alenina N, Coffman TM, Facemire CS, Hilgers KF, Eckardt KU, Wagner C, Kurtz A, Developmental renin expression in mice with a defective renin-angiotensin system. Am J Physiol Renal Physiol. 2009 Nov;297(5):F1371-80
3	J:72077 Pentz ES, Lopez ML, Kim HS, Carretero O, Smithies O, Gomez RA, Ren1d and Ren2 cooperate to preserve homeostasis: evidence from mice expressing GFP in place of Ren1d. Physiol Genomics. 2001 Jun 6;6(1):45-55
14	J:67267 Perera EM, Martin H, Seeherunvong T, Kos L, Hughes IA, Hawkins JR, Berkovitz GD, Tescalcin, a novel gene encoding a putative EF-hand Ca(2+)-binding protein, Col9a3, and renin are expressed in the mouse testis during the early stages of gonadal differentiation. Endocrinology. 2001 Jan;142(1):455-63
1	J:137729 Schuhmacher AJ, Guerra C, Sauzeau V, Canamero M, Bustelo XR, Barbacid M, A mouse model for Costello syndrome reveals an Ang II-mediated hypertensive condition. J Clin Invest. 2008 Jun;118(6):2169-79
1*	J:121918 Schwab KR, Patterson LT, Hartman HA, Song N, Lang RA, Lin X, Potter SS, Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development. BMC Biol. 2007;5:15
5	J:70875 Sequeira Lopez ML, Pentz ES, Robert B, Abrahamson DR, Gomez RA, Embryonic origin and lineage of juxtaglomerular cells. Am J Physiol Renal Physiol. 2001 Aug;281(2):F345-56
1*	J:36423 Sigmund CD, Jones CA, Mullins JJ, Kim U, Gross KW, Expression of murine renin genes in subcutaneous connective tissue. Proc Natl Acad Sci U S A. 1990 Oct;87(20):7993-7
5	J:74016 Xia Y, Wen H, Prashner HR, Chen R, Inagami T, Catanzaro DF, Kellems RE, Pregnancy-induced changes in renin gene expression in mice. Biol Reprod. 2002 Jan;66(1):135-43