Gene Expression Literature Summary
|
Symbol Name ID |
Ret
ret proto-oncogene MGI:97902 |
| Age | E1.5 | E2.5 | E3.5 | E6.5 | E8 | E8.5 | E9 | E9.5 | E10 | E10.5 | E11 | E11.5 | E12 | E12.5 | E13 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18 | E18.5 | E19 | E19.5 | E20 | E | P |
| Immunohistochemistry (section) | 1 | 5 | 2 | 6 | 2 | 16 | 2 | 22 | 5 | 21 | 1 | 14 | 1 | 11 | 1 | 3 | 2 | 6 | 3 | 15 | 2 | 44 | |||||||||
| In situ RNA (section) | 1 | 1 | 3 | 3 | 23 | 7 | 28 | 13 | 31 | 9 | 39 | 10 | 30 | 7 | 21 | 5 | 17 | 4 | 5 | 9 | 15 | 1 | 1 | 2 | 9 | 53 | |||||
| Immunohistochemistry (whole mount) | 1 | 1 | 4 | 1 | 4 | 5 | 2 | 2 | 1 | 3 | |||||||||||||||||||||
| In situ RNA (whole mount) | 1 | 1 | 2 | 11 | 4 | 32 | 18 | 46 | 2 | 26 | 2 | 8 | 6 | 1 | 8 | 4 | 2 | 1 | 4 | ||||||||||||
| In situ reporter (knock in) | 3 | 1 | 5 | 1 | 8 | 16 | 12 | 1 | 7 | 1 | 6 | 4 | 2 | 2 | 4 | 3 | 13 | ||||||||||||||
| Northern blot | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 4 | |||||||||||||||||||||||
| Western blot | 1 | 1 | 1 | 1 | 1 | 2 | 9 | ||||||||||||||||||||||||
| RT-PCR | 1 | 1 | 1 | 1 | 1 | 2 | 2 | 5 | 14 | 1 | 19 | 1 | 13 | 2 | 13 | 2 | 5 | 3 | 5 | 1 | 6 | 1 | 6 | 2 | 29 | ||||||
| cDNA clones | 1 | ||||||||||||||||||||||||||||||
| RNase protection | 1 | 1 | 1 | 1 |
| Ret ret proto-oncogene (Synonyms: c-Ret, RET51, RET9) | |
| Results | Reference |
| 3 | J:184160 Abdo H, Li L, Lallemend F, Bachy I, Xu XJ, Rice FL, Ernfors P, Dependence on the transcription factor Shox2 for specification of sensory neurons conveying discriminative touch. Eur J Neurosci. 2011 Nov;34(10):1529-41 |
| 3 | J:63377 Abidari JM, Gonzales ET, Inoue K, Lupski JR, Karsenty G, Katsanis N, Identification of novel genes expressed during metanephric induction through single-cell library screening. Kidney Int. 2000 Jun;57(6):2221-8 |
| 1* | J:325730 Ahuja N, Hiltabidle MS, Rajasekhar H, Voss S, Lu SZ, Barlow HR, Cowdin MA, Daniel E, Vaddaraju V, Anandakumar T, Black E, Cleaver O, Maynard C, Endothelial Cyp26b1 restrains murine heart valve growth during development. Dev Biol. 2022 Jun;486:81-95 |
| 1 | J:185715 Ainoya K, Moriguchi T, Ohmori S, Souma T, Takai J, Morita M, Chandler KJ, Mortlock DP, Shimizu R, Engel JD, Lim KC, Yamamoto M, UG4 enhancer-driven GATA-2 and bone morphogenetic protein 4 complementation remedies the CAKUT phenotype in Gata2 hypomorphic mutant mice. Mol Cell Biol. 2012 Jun;32(12):2312-22 |
| 1 | J:106499 Airik R, Bussen M, Singh MK, Petry M, Kispert A, Tbx18 regulates the development of the ureteral mesenchyme. J Clin Invest. 2006 Mar;116(3):663-74 |
| 4* | J:82111 Allmendinger A, Stoeckel E, Saarma M, Unsicker K, Huber K, Development of adrenal chromaffin cells is largely normal in mice lacking the receptor tyrosine kinase c-Ret. Mech Dev. 2003 Mar;120(3):299-304 |
| 4 | J:333984 Altes G, Vaquero M, Cuesta S, Anerillas C, Macia A, Espinet C, Ribera J, Bellusci S, Klein OD, Yeramian A, Dolcet X, Egea J, Encinas M, A dominant negative mutation uncovers cooperative control of caudal Wolffian duct development by Sprouty genes. Cell Mol Life Sci. 2022 Sep 13;79(10):514 |
| 2* | J:121340 Anderson RB, Bergner AJ, Taniguchi M, Fujisawa H, Forrai A, Robb L, Young HM, Effects of different regions of the developing gut on the migration of enteric neural crest-derived cells: a role for Sema3A, but not Sema3F. Dev Biol. 2007 May 1;305(1):287-99 |
| 7 | J:105292 Anderson RB, Stewart AL, Young HM, Phenotypes of neural-crest-derived cells in vagal and sacral pathways. Cell Tissue Res. 2006 Jan;323(1):11-25 |
| 1 | J:294835 Anslow MJ, Bodnar AJ, Cerqueira DM, Bushnell D, Shrom BE, Sims-Lucas S, Bates CM, Ho J, Increased rates of vesicoureteral reflux in mice from deletion of Dicer in the peri-Wolffian duct stroma. Pediatr Res. 2020 Sep;88(3):382-390 |
| 1 | J:45763 Arce V, Pollock RA, Philippe JM, Pennica D, Henderson CE, deLapeyriere O, Synergistic effects of schwann- and muscle-derived factors on motoneuron survival involve GDNF and cardiotrophin-1 (CT-1). J Neurosci. 1998 Feb 15;18(4):1440-8 |
| 5 | J:116089 Asai N, Fukuda T, Wu Z, Enomoto A, Pachnis V, Takahashi M, Costantini F, Targeted mutation of serine 697 in the Ret tyrosine kinase causes migration defect of enteric neural crest cells. Development. 2006 Nov;133(22):4507-16 |
| 1 | J:58676 Aubin J, Chailler P, Menard D, Jeannotte L, Loss of Hoxa5 gene function in mice perturbs intestinal maturation. Am J Physiol. 1999 Nov;277(5 Pt 1):C965-73 |
| 2 | J:45374 Baloh RH, Tansey MG, Golden JP, Creedon DJ, Heuckeroth RO, Keck CL, Zimonjic DB, Popescu NC, Johnson EM Jr, Milbrandt J, TrnR2, a novel receptor that mediates neurturin and GDNF signaling through Ret. Neuron. 1997 May;18(5):793-802 |
| 4* | J:201549 Bando T, Morikawa Y, Hisaoka T, Komori T, Miyajima A, Senba E, Dynamic expression pattern of leucine-rich repeat neuronal protein 4 in the mouse dorsal root ganglia during development. Neurosci Lett. 2013 Aug 26;548:73-8 |
| 3 | J:130623 Barlow A, de Graaff E, Pachnis V, Enteric nervous system progenitors are coordinately controlled by the G protein-coupled receptor EDNRB and the receptor tyrosine kinase RET. Neuron. 2003 Dec 4;40(5):905-16 |
| 2 | J:193269 Barlow AJ, Dixon J, Dixon M, Trainor PA, Tcof1 acts as a modifier of Pax3 during enteric nervous system development and in the pathogenesis of colonic aganglionosis. Hum Mol Genet. 2013 Mar 15;22(6):1206-17 |
| 1 | J:181887 Barlow AJ, Dixon J, Dixon MJ, Trainor PA, Balancing neural crest cell intrinsic processes with those of the microenvironment in Tcof1 haploinsufficient mice enables complete enteric nervous system formation. Hum Mol Genet. 2012 Apr 15;21(8):1782-93 |
| 2 | J:288459 Bartesaghi L, Wang Y, Fontanet P, Wanderoy S, Berger F, Wu H, Akkuratova N, Boucanova F, Medard JJ, Petitpre C, Landy MA, Zhang MD, Harrer P, Stendel C, Stucka R, Dusl M, Kastriti ME, Croci L, Lai HC, Consalez GG, Pattyn A, Ernfors P, Senderek J, Adameyko I, Lallemend F, Hadjab S, Chrast R, PRDM12 Is Required for Initiation of the Nociceptive Neuron Lineage during Neurogenesis. Cell Rep. 2019 Mar 26;26(13):3484-3492.e4 |
| 2 | J:96485 Basson MA, Akbulut S, Watson-Johnson J, Simon R, Carroll TJ, Shakya R, Gross I, Martin GR, Lufkin T, McMahon AP, Wilson PD, Costantini FD, Mason IJ, Licht JD, Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction. Dev Cell. 2005 Feb;8(2):229-39 |
| 1 | J:208419 Basta JM, Robbins L, Kiefer SM, Dorsett D, Rauchman M, Sall1 balances self-renewal and differentiation of renal progenitor cells. Development. 2014 Mar;141(5):1047-58 |
| 3 | J:78712 Batourina E, Choi C, Paragas N, Bello N, Hensle T, Costantini FD, Schuchardt A, Bacallao RL, Mendelsohn CL, Distal ureter morphogenesis depends on epithelial cell remodeling mediated by vitamin A and Ret. Nat Genet. 2002 Sep;32(1):109-15 |
| 2* | J:79420 Batourina E, Gim S, Bello N, Shy M, Clagett-Dame M, Srinivas S, Costantini F, Mendelsohn C, Vitamin A controls epithelial/mesenchymal interactions through Ret expression. Nat Genet. 2001 Jan;27(1):74-8 |
| 3 | J:64589 Baudet C, Mikaels A, Westphal H, Johansen J, Johansen TE, Ernfors P, Positive and negative interactions of GDNF, NTN and ART in developing sensory neuron subpopulations, and their collaboration with neurotrophins. Development. 2000 Oct;127(20):4335-44 |
| 4 | J:131770 Baudet C, Pozas E, Adameyko I, Andersson E, Ericson J, Ernfors P, Retrograde signaling onto Ret during motor nerve terminal maturation. J Neurosci. 2008 Jan 23;28(4):963-75 |
| 1* | J:245526 Bibollet-Bahena O, Okafuji T, Hokamp K, Tear G, Mitchell KJ, A dual-strategy expression screen for candidate connectivity labels in the developing thalamus. PLoS One. 2017;12(5):e0177977 |
| 1 | J:229163 Blake J, Hu D, Cain JE, Rosenblum ND, Urogenital development in Pallister-Hall syndrome is disrupted in a cell-lineage-specific manner by constitutive expression of GLI3 repressor. Hum Mol Genet. 2016 Feb 1;25(3):437-47 |
| 1* | J:81634 Blaugrund E, Pham TD, Tennyson VM, Lo L, Sommer L, Anderson DJ, Gershon MD, Distinct subpopulations of enteric neuronal progenitors defined by time of development, sympathoadrenal lineage markers and Mash-1-dependence. Development. 1996 Jan;122(1):309-20 |
| 1 | J:140204 Bogni S, Trainor P, Natarajan D, Krumlauf R, Pachnis V, Non-cell-autonomous effects of Ret deletion in early enteric neurogenesis. Development. 2008 Sep;135(18):3007-11 |
| 2 | J:232968 Boivin FJ, Sarin S, Lim J, Javidan A, Svajger B, Khalili H, Bridgewater D, Stromally expressed beta-catenin modulates Wnt9b signaling in the ureteric epithelium. PLoS One. 2015;10(3):e0120347 |
| 1 | J:90843 Bolon B, Jing S, Asuncion F, Scully S, Pisegna M, Van GY, Hu Z, Yu YB, Min H, Wild K, Rosenfeld RD, Tarpley J, Carnahan J, Duryea D, Hill D, Kaufman S, Yan XQ, Juan T, Christensen K, McCabe J, Simonet WS, The candidate neuroprotective agent artemin induces autonomic neural dysplasia without preventing peripheral nerve dysfunction. Toxicol Pathol. 2004 May-Jun;32(3):275-94 |
| 4 | J:180801 Bonanomi D, Chivatakarn O, Bai G, Abdesselem H, Lettieri K, Marquardt T, Pierchala BA, Pfaff SL, Ret Is a Multifunctional Coreceptor that Integrates Diffusible- and Contact-Axon Guidance Signals. Cell. 2012 Feb 3;148(3):568-82 |
| 1 | J:174353 Boualia SK, Gaitan Y, Murawski I, Nadon R, Gupta IR, Bouchard M, Vesicoureteral reflux and other urinary tract malformations in mice compound heterozygous for pax2 and emx2. PLoS One. 2011;6(6):e21529 |
| 1 | J:80208 Bouchard M, Souabni A, Mandler M, Neubuser A, Busslinger M, Nephric lineage specification by Pax2 and Pax8. Genes Dev. 2002 Nov 15;16(22):2958-70 |
| 2 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
| 4 | J:157721 Bourane S, Garces A, Venteo S, Pattyn A, Hubert T, Fichard A, Puech S, Boukhaddaoui H, Baudet C, Takahashi S, Valmier J, Carroll P, Low-threshold mechanoreceptor subtypes selectively express MafA and are specified by Ret signaling. Neuron. 2009 Dec 24;64(6):857-70 |
| 3* | J:136068 Bridgewater D, Cox B, Cain J, Lau A, Athaide V, Gill PS, Kuure S, Sainio K, Rosenblum ND, Canonical WNT/beta-catenin signaling is required for ureteric branching. Dev Biol. 2008 May 1;317(1):83-94 |
| 1 | J:48515 Britsch S, Li L, Kirchhoff S, Theuring F, Brinkmann V, Birchmeier C, Riethmacher D, The ErbB2 and ErbB3 receptors and their ligand, neuregulin-1, are essential for development of the sympathetic nervous system. Genes Dev. 1998 Jun 15;12(12):1825-36 |
| 2* | J:72723 Brophy PD, Ostrom L, Lang KM, Dressler GR, Regulation of ureteric bud outgrowth by Pax2-dependent activation of the glial derived neurotrophic factor gene. Development. 2001 Dec;128(23):4747-56 |
| 1 | J:180898 Brown AS, Epstein DJ, Otic ablation of smoothened reveals direct and indirect requirements for Hedgehog signaling in inner ear development. Development. 2011 Sep;138(18):3967-76 |
| 1 | J:239251 Brzoska HL, d'Esposito AM, Kolatsi-Joannou M, Patel V, Igarashi P, Lei Y, Finnell RH, Lythgoe MF, Woolf AS, Papakrivopoulou E, Long DA, Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning. Kidney Int. 2016 Dec;90(6):1274-1284 |
| 3 | J:48481 Bullock SL, Fletcher JM, Beddington RS, Wilson VA, Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase. Genes Dev. 1998 Jun 15;12(12):1894-906 |
| 1 | J:172032 Cain JE, Islam E, Haxho F, Blake J, Rosenblum ND, GLI3 repressor controls functional development of the mouse ureter. J Clin Invest. 2011 Mar 1;121(3):1199-206 |
| 2 | J:154102 Cain JE, Islam E, Haxho F, Chen L, Bridgewater D, Nieuwenhuis E, Hui CC, Rosenblum ND, GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells. PLoS One. 2009;4(10):e7313 |
| 2 | J:138626 Callahan T, Young HM, Anderson RB, Enomoto H, Anderson CR, Development of satellite glia in mouse sympathetic ganglia: GDNF and GFRalpha1 are not essential. Glia. 2008 Oct;56(13):1428-37 |
| 1 | J:171024 Calmont A, Thapar N, Scambler PJ, Burns AJ, Absence of the vagus nerve in the stomach of Tbx1-/- mutant mice. Neurogastroenterol Motil. 2011 Feb;23(2):125-30 |
| 4 | J:107335 Carniti C, Belluco S, Riccardi E, Cranston AN, Mondellini P, Ponder BA, Scanziani E, Pierotti MA, Bongarzone I, The Ret(C620R) mutation affects renal and enteric development in a mouse model of Hirschsprung's disease. Am J Pathol. 2006 Apr;168(4):1262-75 |
| 1 | J:100575 Carroll TJ, Park JS, Hayashi S, Majumdar A, McMahon AP, Wnt9b plays a central role in the regulation of mesenchymal to epithelial transitions underlying organogenesis of the mammalian urogenital system. Dev Cell. 2005 Aug;9(2):283-92 |
| 1* | J:112220 Caruana G, Cullen-McEwen L, Nelson AL, Kostoulias X, Woods K, Gardiner B, Davis MJ, Taylor DF, Teasdale RD, Grimmond SM, Little MH, Bertram JF, Spatial gene expression in the T-stage mouse metanephros. Gene Expr Patterns. 2006 Dec;6(8):807-25 |
| 1 | J:322321 Catela C, Chen Y, Weng Y, Wen K, Kratsios P, Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity. Elife. 2022 Mar 22;11:e70766 |
| 3 | J:277959 Catela C, Shin MM, Lee DH, Liu JP, Dasen JS, Hox Proteins Coordinate Motor Neuron Differentiation and Connectivity Programs through Ret/Gfralpha Genes. Cell Rep. 2016 Mar 1;14(8):1901-15 |
| 2* | J:98366 Chan KK, Chen YS, Yau TO, Fu M, Lui VC, Tam PK, Sham MH, Hoxb3 vagal neural crest-specific enhancer element for controlling enteric nervous system development. Dev Dyn. 2005 Jun;233(2):473-83 |
| 2 | J:188327 Charoy C, Nawabi H, Reynaud F, Derrington E, Bozon M, Wright K, Falk J, Helmbacher F, Kindbeiter K, Castellani V, gdnf Activates Midline Repulsion by Semaphorin3B via NCAM during Commissural Axon Guidance. Neuron. 2012 Sep 20;75(6):1051-66 |
| 2 | J:236524 Chatterjee S, Kapoor A, Akiyama JA, Auer DR, Lee D, Gabriel S, Berrios C, Pennacchio LA, Chakravarti A, Enhancer Variants Synergistically Drive Dysfunction of a Gene Regulatory Network In Hirschsprung Disease. Cell. 2016 Oct 6;167(2):355-368.e10 |
| 4 | J:106971 Chen CL, Broom DC, Liu Y, de Nooij JC, Li Z, Cen C, Samad OA, Jessell TM, Woolf CJ, Ma Q, Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain. Neuron. 2006 Feb 2;49(3):365-77 |
| 2 | J:238877 Chen S, Yao X, Li Y, Saifudeen Z, Bachvarov D, El-Dahr SS, Histone deacetylase 1 and 2 regulate Wnt and p53 pathways in the ureteric bud epithelium. Development. 2015 Mar 15;142(6):1180-92 |
| 1* | J:187163 Chen TR, Wang P, Carroll LK, Zhang YJ, Han BX, Wang F, Generation and characterization of Tmeff2 mutant mice. Biochem Biophys Res Commun. 2012 Aug 24;425(2):189-94 |
| 1* | J:254788 Chen Z, Donnelly CR, Dominguez B, Harada Y, Lin W, Halim AS, Bengoechea TG, Pierchala BA, Lee KF, p75 Is Required for the Establishment of Postnatal Sensory Neuron Diversity by Potentiating Ret Signaling. Cell Rep. 2017 Oct 17;21(3):707-720 |
| 1 | J:70560 Chen Z, Rebelo S, White F, Malmberg AB, Baba H, Lima D, Woolf CJ, Basbaum AI, Anderson DJ, The paired homeodomain protein drg11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord. Neuron. 2001 Jul 19;31(1):59-73 |
| 5 | J:268047 Cheng I, Jin L, Rose LC, Deppmann CD, Temporally restricted death and the role of p75NTR as a survival receptor in the developing sensory nervous system. Dev Neurobiol. 2018 Jul;78(7):701-717 |
| 1 | J:203312 Chi L, Galtseva A, Chen L, Mo R, Hui CC, Rosenblum ND, Kif3a controls murine nephron number via GLI3 repressor, cell survival, and gene expression in a lineage-specific manner. PLoS One. 2013;8(6):e65448 |
| 1* | J:180958 Chi L, Saarela U, Railo A, Prunskaite-Hyyrylainen R, Skovorodkin I, Anthony S, Katsu K, Liu Y, Shan J, Salgueiro AM, Belo JA, Davies J, Yokouchi Y, Vainio SJ, A secreted BMP antagonist, Cer1, fine tunes the spatial organization of the ureteric bud tree during mouse kidney development. PLoS One. 2011;6(11):e27676 |
| 2 | J:91010 Chi L, Zhang S, Lin Y, Prunskaite-Hyyrylainen R, Vuolteenaho R, Itaranta P, Vainio S, Sprouty proteins regulate ureteric branching by coordinating reciprocal epithelial Wnt11, mesenchymal Gdnf and stromal Fgf7 signalling during kidney development. Development. 2004 Jul;131(14):3345-56 |
| 1* | J:171426 Chia I, Grote D, Marcotte M, Batourina E, Mendelsohn C, Bouchard M, Nephric duct insertion is a crucial step in urinary tract maturation that is regulated by a Gata3-Raldh2-Ret molecular network in mice. Development. 2011 May;138(10):2089-97 |
| 2 | J:348800 Clark JF, Soriano P, Diverse Fgfr1 signaling pathways and endocytic trafficking regulate mesoderm development. Genes Dev. 2024 Jun 4; |
| 1* | J:100439 Cohen S, Funkelstein L, Livet J, Rougon G, Henderson CE, Castellani V, Mann F, A semaphorin code defines subpopulations of spinal motor neurons during mouse development. Eur J Neurosci. 2005 Apr;21(7):1767-76 |
| 1 | J:166770 Coppola E, d'Autreaux F, Rijli FM, Brunet JF, Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation. Development. 2010 Dec;137(24):4211-20 |
| 2 | J:126634 Coppola E, Pattyn A, Guthrie SC, Goridis C, Studer M, Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation. EMBO J. 2005 Dec 21;24(24):4392-403 |
| 1* | J:166924 Cross SH, McKie L, West K, Coghill EL, Favor J, Bhattacharya S, Brown SD, Jackson IJ, The Opdc missense mutation of Pax2 has a milder than loss-of-function phenotype. Hum Mol Genet. 2011 Jan 15;20(2):223-34 |
| 1 | J:194303 D R D, M R, Mi-2/NuRD is required in renal progenitor cells during embryonic kidney development. Dev Biol. 2013 Mar 15;375(2):105-16 |
| 1 | J:180432 D'Autreaux F, Coppola E, Hirsch MR, Birchmeier C, Brunet JF, Homeoprotein Phox2b commands a somatic-to-visceral switch in cranial sensory pathways. Proc Natl Acad Sci U S A. 2011 Dec 13;108(50):20018-23 |
| 1 | J:135127 D'Autreaux F, Morikawa Y, Cserjesi P, Gershon MD, Hand2 is necessary for terminal differentiation of enteric neurons from crest-derived precursors but not for their migration into the gut or for formation of glia. Development. 2007 Jun;134(12):2237-49 |
| 1 | J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400 |
| 1* | J:291486 Daniel E, Barlow HR, Sutton GI, Gu X, Htike Y, Cowdin MA, Cleaver O, Cyp26b1 is an essential regulator of distal airway epithelial differentiation during lung development. Development. 2020 Feb 20;147(4):dev181560 |
| 6 | J:71588 de Graaff E, Srinivas S, Kilkenny C, D'Agati V, Mankoo BS, Costantini F, Pachnis V, Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis. Genes Dev. 2001 Sep 15;15(18):2433-44 |
| 3* | J:308929 De Vincenti AP, Alsina FC, Ferrero Restelli F, Hedman H, Ledda F, Paratcha G, Lrig1 and Lrig3 cooperate to control Ret receptor signaling, sensory axonal growth and epidermal innervation. Development. 2021 Aug 15;148(16):dev197020 |
| 1 | J:340939 Deacon E, Li A, Boivin F, Dvorkin-Gheva A, Cunanan J, Bridgewater D, beta-Catenin in the kidney stroma modulates pathways and genes to regulate kidney development. Dev Dyn. 2023 Sep;252(9):1224-1239 |
| 2 | J:270523 Desgrange A, Heliot C, Skovorodkin I, Akram SU, Heikkila J, Ronkainen VP, Miinalainen I, Vainio SJ, Cereghini S, HNF1B controls epithelial organization and cell polarity during ureteric bud branching and collecting duct morphogenesis. Development. 2017 Dec 15;144(24):4704-4719 |
| 2 | J:353354 Desiderio S, Schwaller F, Tartour K, Padmanabhan K, Lewin GR, Carroll P, Marmigere F, Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2. Elife. 2024 Feb 22;12 |
| 1 | J:283226 Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld KA, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ, Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA. Cell Rep. 2019 Mar 26;26(13):3522-3536.e5 |
| 1 | J:173576 Di Giovanni V, Alday A, Chi L, Mishina Y, Rosenblum ND, Alk3 controls nephron number and androgen production via lineage-specific effects in intermediate mesoderm. Development. 2011 Jul;138(13):2717-27 |
| 1 | J:260552 Donnelly CR, Shah AA, Mistretta CM, Bradley RM, Pierchala BA, Biphasic functions for the GDNF-Ret signaling pathway in chemosensory neuron development and diversification. Proc Natl Acad Sci U S A. 2018 Jan 16;115(3):E516-E525 |
| 2 | J:30057 Dudley AT, Lyons KM, Robertson EJ, A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev. 1995 NOV 15;9(22):2795-2807 |
| 5 | J:30830 Durbec PL, Larsson-Blomberg LB, Schuchardt A, Costantini F, Pachnis V, Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts. Development. 1996 Jan;122(1):349-58 |
| 3 | J:211702 Dyachuk V, Furlan A, Shahidi MK, Giovenco M, Kaukua N, Konstantinidou C, Pachnis V, Memic F, Marklund U, Muller T, Birchmeier C, Fried K, Ernfors P, Adameyko I, Neurodevelopment. Parasympathetic neurons originate from nerve-associated peripheral glial progenitors. Science. 2014 Jul 4;345(6192):82-7 |
| 2 | J:160718 Dykes IM, Lanier J, Eng SR, Turner EE, Brn3a regulates neuronal subtype specification in the trigeminal ganglion by promoting Runx expression during sensory differentiation. Neural Dev. 2010;5:3 |
| 1 | J:174563 Dykes IM, Tempest L, Lee SI, Turner EE, Brn3a and Islet1 act epistatically to regulate the gene expression program of sensory differentiation. J Neurosci. 2011 Jul 6;31(27):9789-99 |
| 3 | J:114185 Enomoto H, Heuckeroth RO, Golden JP, Johnson EM, Milbrandt J, Development of cranial parasympathetic ganglia requires sequential actions of GDNF and neurturin. Development. 2000 Nov;127(22):4877-89 |
| 2 | J:130616 Enomoto H, Hughes I, Golden J, Baloh RH, Yonemura S, Heuckeroth RO, Johnson EM Jr, Milbrandt J, GFRalpha1 expression in cells lacking RET is dispensable for organogenesis and nerve regeneration. Neuron. 2004 Nov 18;44(4):623-36 |
| 1* | J:35809 Epstein DJ, Marti E, Scott MP, McMahon AP, Antagonizing cAMP-dependent protein kinase A in the dorsal CNS activates a conserved Sonic hedgehog signaling pathway. Development. 1996 Sep;122(9):2885-94 |
| 1 | J:109404 Erickson JT, Brosenitsch TA, Katz DM, Brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor are required simultaneously for survival of dopaminergic primary sensory neurons in vivo. J Neurosci. 2001 Jan 15;21(2):581-9 |
| 1* | J:83365 Esquela AF, Lee SJ, Regulation of metanephric kidney development by growth/differentiation factor 11. Dev Biol. 2003 May 15;257(2):356-70 |
| 1 | J:202649 Evangelisti C, Bianco F, Pradella LM, Puliti A, Goldoni A, Sbrana I, Rossi M, Vargiolu M, Seri M, Romeo G, Stanghellini V, de Giorgio R, Bonora E, Apolipoprotein B is a new target of the GDNF/RET and ET-3/EDNRB signalling pathways. Neurogastroenterol Motil. 2012 Oct;24(10):e497-508 |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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