Gene Expression Literature Summary

• Symbol: Snrpn
• Name: small nuclear ribonucleoprotein N
• ID: MGI:98347

38 matching records from 38 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E3.5	E4.5	E5.5	E6.5	E7.5	E8.5	E9.5	E10	E10.5	E11	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18.5	E19	E	P
In situ RNA (section)												1		1		2		1	1		1		1
In situ RNA (whole mount)									1			1
Northern blot			1				2							1										1	2
RT-PCR	2	1		2	2	1	9	1	5	1	1	3	1	2	1	2	2		2	2	1	1	1		5	12
cDNA clones							1
Primer Extension														1												1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Snrpn  small nuclear ribonucleoprotein N   (Synonyms: 2410045I01Rik, MGC:18604, MGC:30325, Peg4, Pwcr1)
Results	Reference
2	J:112884 Arima T, Hata K, Tanaka S, Kusumi M, Li E, Kato K, Shiota K, Sasaki H, Wake N, Loss of the maternal imprint in Dnmt3Lmat-/- mice leads to a differentiation defect in the extraembryonic tissue. Dev Biol. 2006 Sep 15;297(2):361-73
9	J:106778 Arnaud P, Hata K, Kaneda M, Li E, Sasaki H, Feil R, Kelsey G, Stochastic imprinting in the progeny of Dnmt3L-/- females. Hum Mol Genet. 2006 Feb 15;15(4):589-98
8	J:26119 Barr JA, Jones J, Glenister PH, Cattanach BM, Ubiquitous expression and imprinting of Snrpn in the mouse. Mamm Genome. 1995 Jun;6(6):405-7
1	J:73452 Bourc'his D, Xu GL, Lin CS, Bollman B, Bestor TH, Dnmt3L and the establishment of maternal genomic imprints. Science. 2001 Dec 21;294(5551):2536-9
4	J:41347 Cattanach BM, Barr JA, Beechey CV, Martin J, Noebels J, Jones J, A candidate model for Angelman syndrome in the mouse. Mamm Genome. 1997 Jul;8(7):472-8
1	J:152382 Ciccone DN, Su H, Hevi S, Gay F, Lei H, Bajko J, Xu G, Li E, Chen T, KDM1B is a histone H3K4 demethylase required to establish maternal genomic imprints. Nature. 2009 Sep 17;461(7262):415-8
2	J:135338 Cirio MC, Ratnam S, Ding F, Reinhart B, Navara C, Chaillet JR, Preimplantation expression of the somatic form of Dnmt1 suggests a role in the inheritance of genomic imprints. BMC Dev Biol. 2008;8:9
2	J:332803 de Waal E, Mak W, Calhoun S, Stein P, Ord T, Krapp C, Coutifaris C, Schultz RM, Bartolomei MS, In vitro culture increases the frequency of stochastic epigenetic errors at imprinted genes in placental tissues from mouse concepti produced through assisted reproductive technologies. Biol Reprod. 2014 Feb;90(2):22
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
2	J:206605 Faisal M, Kim H, Kim J, Sexual differences of imprinted genes' expression levels. Gene. 2014 Jan 1;533(1):434-8
1	J:174189 Ferron SR, Charalambous M, Radford E, McEwen K, Wildner H, Hind E, Morante-Redolat JM, Laborda J, Guillemot F, Bauer SR, Farinas I, Ferguson-Smith AC, Postnatal loss of Dlk1 imprinting in stem cells and niche astrocytes regulates neurogenesis. Nature. 2011 Jul 21;475(7356):381-5
1	J:108137 Fukasawa M, Morita S, Kimura M, Horii T, Ochiya T, Hatada I, Genomic imprinting in Dicer1-hypomorphic mice. Cytogenet Genome Res. 2006;113(1-4):138-43
1	J:204566 Gendrel AV, Tang YA, Suzuki M, Godwin J, Nesterova TB, Greally JM, Heard E, Brockdorff N, Epigenetic functions of smchd1 repress gene clusters on the inactive X chromosome and on autosomes. Mol Cell Biol. 2013 Aug;33(16):3150-65
1*	J:57890 Gerard M, Hernandez L, Wevrick R, Stewart CL, Disruption of the mouse necdin gene results in early post-natal lethality [see comments]. Nat Genet. 1999 Oct;23(2):199-202
1*	J:75938 Hata K, Okano M, Lei H, Li E, Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice. Development. 2002 Apr;129(8):1983-93
1*	J:68455 Howell CY, Bestor TH, Ding F, Latham KE, Mertineit C, Trasler JM, Chaillet JR, Genomic imprinting disrupted by a maternal effect mutation in the Dnmt1 gene. Cell. 2001 Mar 23;104(6):829-38
1	J:302583 Jiang W, Shi J, Zhao J, Wang Q, Cong D, Chen F, Zhang Y, Liu Y, Zhao J, Chen Q, Gu L, Zhou W, Wang C, Fang Z, Geng S, Xie W, Chen LN, Yang Y, Bai Y, Lin H, Li X, ZFP57 dictates allelic expression switch of target imprinted genes. Proc Natl Acad Sci U S A. 2021 Feb 2;118(5):e2005377118
1*	J:91108 Kaneda M, Okano M, Hata K, Sado T, Tsujimoto N, Li E, Sasaki H, Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting. Nature. 2004 Jun 24;429(6994):900-3
1	J:28395 Kaneko-Ishino T, Kuroiwa Y, Miyoshi N, Kohda T, Suzuki R, Yokoyama M, Viville S, Barton SC, Ishino F, Surani MA, Peg1/Mest imprinted gene on chromosome 6 identified by cDNA subtraction hybridization. Nat Genet. 1995 Sep;11(1):52-9
3	J:169234 Kim JD, Kim H, Ekram MB, Yu S, Faulk C, Kim J, Rex1/Zfp42 as an epigenetic regulator for genomic imprinting. Hum Mol Genet. 2011 Apr 1;20(7):1353-62
6	J:85656 Lee S, Walker CL, Wevrick R, Prader-Willi syndrome transcripts are expressed in phenotypically significant regions of the developing mouse brain. Gene Expr Patterns. 2003 Oct;3(5):599-609
3*	J:148106 Lopes FL, Fortier AL, Darricarrere N, Chan D, Arnold DR, Trasler JM, Reproductive and epigenetic outcomes associated with aging mouse oocytes. Hum Mol Genet. 2009 Jun 1;18(11):2032-44
1	J:82790 Mager J, Montgomery ND, de Villena FP, Magnuson T, Genome imprinting regulated by the mouse Polycomb group protein Eed. Nat Genet. 2003 Apr;33(4):502-7
2	J:29864 Mann M, Latham KE, Varmuza S, Identification of genes showing altered expression in preimplantation and early postimplantation parthenogenetic embryos. Dev Genet. 1995;17(3):223-32
3*	J:267655 Marjonen H, Toivonen M, Lahti L, Kaminen-Ahola N, Early prenatal alcohol exposure alters imprinted gene expression in placenta and embryo in a mouse model. PLoS One. 2018;13(5):e0197461
2*	J:30829 McLaughlin KJ, Szabo P, Haegel H, Mann JR, Mouse embryos with paternal duplication of an imprinted chromosome 7 region die at midgestation and lack placental spongiotrophoblast. Development. 1996 Jan;122(1):265-70
1	J:181833 Messerschmidt DM, de Vries W, Ito M, Solter D, Ferguson-Smith A, Knowles BB, Trim28 is required for epigenetic stability during mouse oocyte to embryo transition. Science. 2012 Mar 23;335(6075):1499-502
1	J:121791 Morita S, Horii T, Kimura M, Goto Y, Ochiya T, Hatada I, One Argonaute family member, Eif2c2 (Ago2), is essential for development and appears not to be involved in DNA methylation. Genomics. 2007 Jun;89(6):687-696
2	J:355918 Mould AW, Pang Z, Pakusch M, Tonks ID, Stark M, Carrie D, Mukhopadhyay P, Seidel A, Ellis JJ, Deakin J, Wakefield MJ, Krause L, Blewitt ME, Kay GF, Smchd1 regulates a subset of autosomal genes subject to monoallelic expression in addition to being critical for X inactivation. Epigenetics Chromatin. 2013 Jul 2;6(1):19
1	J:217174 Nakagaki A, Osanai H, Kishino T, Imprinting analysis of the mouse chromosome 7C region in DNMT1-null embryos. Gene. 2014 Dec 10;553(1):63-8
2*	J:47783 Obata Y, Kaneko-Ishino T, Koide T, Takai Y, Ueda T, Domeki I , Shiroishi T , Ishino F , Kono T, Disruption of primary imprinting during oocyte growth leads to the modified expression of imprinted genes during embryogenesis. Development. 1998 Apr;125(8):1553-60
1	J:112969 Ogawa H, Wu Q, Komiyama J, Obata Y, Kono T, Disruption of parental-specific expression of imprinted genes in uniparental fetuses. FEBS Lett. 2006 Oct 2;580(22):5377-84
1*	J:177918 Quille ML, Carat S, Quemener-Redon S, Hirchaud E, Baron D, Benech C, Guihot J, Placet M, Mignen O, Ferec C, Houlgatte R, Friocourt G, High-throughput analysis of promoter occupancy reveals new targets for Arx, a gene mutated in mental retardation and interneuronopathies. PLoS One. 2011;6(9):e25181
1*	J:42929 Shemer R, Birger Y, Riggs AD, Razin A, Structure of the imprinted mouse Snrpn gene and establishment of its parental-specific methylation pattern. Proc Natl Acad Sci U S A. 1997 Sep 16;94(19):10267-72
1*	J:152022 Skryabin BV, Gubar LV, Seeger B, Pfeiffer J, Handel S, Robeck T, Karpova E, Rozhdestvensky TS, Brosius J, Deletion of the MBII-85 snoRNA gene cluster in mice results in postnatal growth retardation. PLoS Genet. 2007 Dec 28;3(12):e235
1	J:172308 Stefan M, Simmons RA, Bertera S, Trucco M, Esni F, Drain P, Nicholls RD, Global deficits in development, function, and gene expression in the endocrine pancreas in a deletion mouse model of Prader-Willi syndrome. Am J Physiol Endocrinol Metab. 2011 May;300(5):E909-22
6	J:30428 Szabo PE, Mann JR, Allele-specific expression and total expression levels of imprinted genes during early mouse development: implications for imprinting mechanisms. Genes Dev. 1995 Dec 15;9(24):3097-108
1	J:101829 Watrin F, Le Meur E, Roeckel N, Ripoche MA, Dandolo L, Muscatelli F, The Prader-Willi syndrome murine imprinting center is not involved in the spatio-temporal transcriptional regulation of the Necdin gene. BMC Genet. 2005 Jan 5;6(1):1