Gene Expression Literature Summary

• Symbol: Sod1
• Name: superoxide dismutase 1, soluble
• ID: MGI:98351

46 matching records from 46 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E3.5	E7.5	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13.5	E14	E14.5	E15	E15.5	E16.5	E17.5	E18	E18.5	E19	E	P
Immunohistochemistry (section)														2		1		1	1	1		3			1
In situ RNA (section)											1			1		3		2	1	1		2			1
In situ RNA (whole mount)				1	1		2		2		1		1	1										1
Northern blot							1		1		1		1	1		1		1	1	1		1			2
Western blot					1	1	2		2		1	1	1	2		1	1	1	2	1	1	3			8
RT-PCR	1	1	1	1	4		4	1	3	1	3	1	2	2	1	2	1	2	1	1	2	3	1	2	15
cDNA clones																									1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Sod1  superoxide dismutase 1, soluble   (Synonyms: B430204E11Rik, Cu(2+)-Zn2+ superoxide dismutase, Cu/Zn-SOD, CuZnSOD, Ipo-1, Ipo1, Sod-1, SODC)
Results	Reference
2	J:106998 Avossa D, Grandolfo M, Mazzarol F, Zatta M, Ballerini L, Early signs of motoneuron vulnerability in a disease model system: Characterization of transverse slice cultures of spinal cord isolated from embryonic ALS mice. Neuroscience. 2006;138(4):1179-94
2*	J:71941 Baumgart E, Vanhorebeek I, Grabenbauer M, Borgers M, Declercq PE, Fahimi HD, Baes M, Mitochondrial alterations caused by defective peroxisomal biogenesis in a mouse model for Zellweger syndrome (PEX5 knockout mouse). Am J Pathol. 2001 Oct;159(4):1477-94
2*	J:144699 Bechara EG, Didiot MC, Melko M, Davidovic L, Bensaid M, Martin P, Castets M, Pognonec P, Khandjian EW, Moine H, Bardoni B, A novel function for fragile X mental retardation protein in translational activation. PLoS Biol. 2009 Jan 20;7(1):e16
4*	J:150363 Chung YW, Jeong D, Noh OJ, Park YH, Kang SI, Lee MG, Lee TH, Yim MB, Kim IY, Antioxidative role of selenoprotein W in oxidant-induced mouse embryonic neuronal cell death. Mol Cells. 2009 May;27(5):609-13
2	J:353356 da Cunha Menezes E, de Abreu FF, Davis JB, Maurer SV, Roshko VC, Richardson A, Dowell J, Cassella SN, Stevens HE, Effects of gestational hypothyroidism on mouse brain development: Gabaergic systems and oxidative stress. Dev Biol. 2024 Nov;515:112-120
12*	J:17746 de Haan JB, Tymms MJ, Cristiano F, Kola I, Expression of copper/zinc superoxide dismutase and glutathione peroxidase in organs of developing mouse embryos, fetuses, and neonates. Pediatr Res. 1994 Feb;35(2):188-96
2	J:330375 Dionne G, Calder M, Betts DH, Rafea BA, Watson AJ, Expression and localization of NRF2/Keap1 signalling pathway genes in mouse preimplantation embryos exposed to free fatty acids. Gene Expr Patterns. 2022 Oct 13;46:119281
1	J:233087 Dong D, Yu J, Wu Y, Fu N, Villela NA, Yang P, Maternal diabetes triggers DNA damage and DNA damage response in neurulation stage embryos through oxidative stress. Biochem Biophys Res Commun. 2015 Nov 13;467(2):407-12
2*	J:57158 El Mouatassim S, Guerin P, Menezo Y, Expression of genes encoding antioxidant enzymes in human and mouse oocytes during the final stages of maturation. Mol Hum Reprod. 1999 Aug;5(8):720-5
1*	J:250104 Flodby P, Li C, Liu Y, Wang H, Marconett CN, Laird-Offringa IA, Minoo P, Lee AS, Zhou B, The 78-kD Glucose-Regulated Protein Regulates Endoplasmic Reticulum Homeostasis and Distal Epithelial Cell Survival during Lung Development. Am J Respir Cell Mol Biol. 2016 Jul;55(1):135-49
1*	J:80501 Gitton Y, Dahmane N, Baik S, Ruiz I Altaba A, Neidhardt L, Scholze M, Herrmann BG, Kahlem P, Benkahla A, Schrinner S, Yildirimman R, Herwig R, Lehrach H, Yaspo ML, A gene expression map of human chromosome 21 orthologues in the mouse. Nature. 2002 Dec 5;420(6915):586-90
2	J:314936 Gumusoglu SB, Chilukuri ASS, Hing BWQ, Scroggins SM, Kundu S, Sandgren JA, Santillan MK, Santillan DA, Grobe JL, Stevens HE, Altered offspring neurodevelopment in an arginine vasopressin preeclampsia model. Transl Psychiatry. 2021 Jan 28;11(1):79
1	J:83128 Hafezparast M, Klocke R, Ruhrberg C, Marquardt A, Ahmad-Annuar A, Bowen S, Lalli G, Witherden AS, Hummerich H, Nicholson S, Morgan PJ, Oozageer R, Priestley JV, Averill S, King VR, Ball S, Peters J, Toda T, Yamamoto A, Hiraoka Y, Augustin M, Korthaus D, Wattler S, Wabnitz P, Dickneite C, Lampel S, Boehme F, Peraus G, Popp A, Rudelius M, Schlegel J, Fuchs H, de Angelis MH, Schiavo G, Shima DT, Russ AP, Stumm G, Martin JE, Fisher EM, Mutations in dynein link motor neuron degeneration to defects in retrograde transport. Science. 2003 May 2;300(5620):808-12
1	J:93248 Hamatani T, Falco G, Carter MG, Akutsu H, Stagg CA, Sharov AA, Dudekula DB, VanBuren V, Ko MS, Age-associated alteration of gene expression patterns in mouse oocytes. Hum Mol Genet. 2004 Nov 1;13(19):2263-78
1	J:29012 Harvey MB, Arcellana-Panlilio MY, Zhang X, Schultz GA, Watson AJ, Expression of genes encoding antioxidant enzymes in preimplantation mouse and cow embryos and primary bovine oviduct cultures employed for embryo coculture. Biol Reprod. 1995 Sep;53(3):532-40
1	J:224310 Ishihara T, Ban-Ishihara R, Maeda M, Matsunaga Y, Ichimura A, Kyogoku S, Aoki H, Katada S, Nakada K, Nomura M, Mizushima N, Mihara K, Ishihara N, Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development. Mol Cell Biol. 2015 Jan;35(1):211-23
1	J:108465 Issa LL, Palmer SJ, Guven KL, Santucci N, Hodgson VR, Popovic K, Joya JE, Hardeman EC, MusTRD can regulate postnatal fiber-specific expression. Dev Biol. 2006 May 1;293(1):104-15
1	J:326350 Keppner A, Correia M, Santambrogio S, Koay TW, Maric D, Osterhof C, Winter DV, Clerc A, Stumpe M, Chalmel F, Dewilde S, Odermatt A, Kressler D, Hankeln T, Wenger RH, Hoogewijs D, Androglobin, a chimeric mammalian globin, is required for male fertility. Elife. 2022 Jun 14;11:e72374
2*	J:82905 Khan JY, Black SM, Developmental changes in murine brain antioxidant enzymes. Pediatr Res. 2003 Jul;54(1):77-82
1	J:98789 Lange AW, Rothermel BA, Yutzey KE, Restoration of DSCR1 to disomy in the trisomy 16 mouse model of Down syndrome does not correct cardiac or craniofacial development anomalies. Dev Dyn. 2005 May 19;233(3):954-963
1	J:180201 Liu C, Morishima M, Yu T, Matsui S, Zhang L, Fu D, Pao A, Costa AC, Gardiner KJ, Cowell JK, Nowak NJ, Parmacek MS, Liang P, Baldini A, Yu YE, Genetic analysis of Down syndrome-associated heart defects in mice. Hum Genet. 2011 Nov;130(5):623-32
1	J:281366 Liu C, Tate T, Batourina E, Truschel ST, Potter S, Adam M, Xiang T, Picard M, Reiley M, Schneider K, Tamargo M, Lu C, Chen X, He J, Kim H, Mendelsohn CL, Pparg promotes differentiation and regulates mitochondrial gene expression in bladder epithelial cells. Nat Commun. 2019 Oct 9;10(1):4589
1*	J:103128 Machka C, Kersten M, Zobawa M, Harder A, Horsch M, Halder T, Lottspeich F, Hrabe de Angelis M, Beckers J, Identification of Dll1 (Delta1) target genes during mouse embryogenesis using differential expression profiling. Gene Expr Patterns. 2005 Dec;6(1):94-101
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1	J:245430 Milczarek A, Starzynski RR, Stys A, Jonczy A, Staron R, Grzelak A, Lipinski P, A drastic superoxide-dependent oxidative stress is prerequisite for the down-regulation of IRP1: Insights from studies on SOD1-deficient mice and macrophages treated with paraquat. PLoS One. 2017;12(5):e0176800
1	J:344186 Munoz-Gallardo MDM, Garcia-Padilla C, Vicente-Garcia C, Carvajal J, Arenega A, Franco D, miR-195b is required for proper cellular homeostasis in the elderly. Sci Rep. 2024 Jan 8;14(1):810
3*	J:82645 Orelio C, Dzierzak E, Identification of 2 novel genes developmentally regulated in the mouse aorta-gonad-mesonephros region. Blood. 2003 Mar 15;101(6):2246-9
1	J:124186 Rebelo S, Reguenga C, Osorio L, Pereira C, Lopes C, Lima D, DRG11 immunohistochemical expression during embryonic development in the mouse. Dev Dyn. 2007 Sep;236(9):2653-60
7*	J:80502 Reymond A, Marigo V, Yaylaoglu MB, Leoni A, Ucla C, Scamuffa N, Caccioppoli C, Dermitzakis ET, Lyle R, Banfi S, Eichele G, Antonarakis SE, Ballabio A, Human chromosome 21 gene expression atlas in the mouse. Nature. 2002 Dec 5;420(6915):582-6
1*	J:82001 Robert K, Vialard F, Thiery E, Toyama K, Sinet PM, Janel N, London J, Expression of the cystathionine beta synthase (CBS) gene during mouse development and immunolocalization in adult brain. J Histochem Cytochem. 2003 Mar;51(3):363-71
1	J:106626 Sanchez-Carbente MR, Castro-Obregon S, Covarrubias L, Narvaez V, Motoneuronal death during spinal cord development is mediated by oxidative stress. Cell Death Differ. 2005 Mar;12(3):279-91
1	J:162790 Sasaki K, Hamazaki J, Koike M, Hirano Y, Komatsu M, Uchiyama Y, Tanaka K, Murata S, PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis. Mol Cell Biol. 2010 Aug;30(15):3864-74
2	J:108566 Schnabel D, Salas-Vidal E, Narvaez V, Sanchez-Carbente Mdel R, Hernandez-Garcia D, Cuervo R, Covarrubias L, Expression and regulation of antioxidant enzymes in the developing limb support a function of ROS in interdigital cell death. Dev Biol. 2006 Mar 15;291(2):291-9
3*	J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265
1	J:308971 Serin N, Dihazi GH, Tayyeb A, Lenz C, Muller GA, Zeisberg M, Dihazi H, Calreticulin Deficiency Disturbs Ribosome Biogenesis and Results in Retardation in Embryonic Kidney Development. Int J Mol Sci. 2021 May 30;22(11)
1	J:141141 Song B, Scheuner D, Ron D, Pennathur S, Kaufman RJ, Chop deletion reduces oxidative stress, improves beta cell function, and promotes cell survival in multiple mouse models of diabetes. J Clin Invest. 2008 Oct;118(10):3378-89
1	J:307814 Tannous C, Deloux R, Karoui A, Mougenot N, Burkin D, Blanc J, Coletti D, Lavery G, Li Z, Mericskay M, NMRK2 Gene Is Upregulated in Dilated Cardiomyopathy and Required for Cardiac Function and NAD Levels during Aging. Int J Mol Sci. 2021 Mar 29;22(7)
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1*	J:238642 Vrbacky M, Kovalcikova J, Chawengsaksophak K, Beck IM, Mracek T, Nuskova H, Sedmera D, Papousek F, Kolar F, Sobol M, Hozak P, Sedlacek R, Houstek J, Knockout of Tmem70 alters biogenesis of ATP synthase and leads to embryonal lethality in mice. Hum Mol Genet. 2016 Nov 01;25(21):4674-4685
2	J:244710 Yamauchi T, Nishiyama M, Moroishi T, Kawamura A, Nakayama KI, FBXL5 Inactivation in Mouse Brain Induces Aberrant Proliferation of Neural Stem Progenitor Cells. Mol Cell Biol. 2017 Apr 15;37(8)
24*	J:127407 Yon JM, Baek IJ, Lee SR, Jin Y, Kim MR, Nahm SS, Kim JS, Ahn B, Lee BJ, Yun YW, Nam SY, The spatio-temporal expression pattern of cytoplasmic Cu/Zn superoxide dismutase (SOD1) mRNA during mouse embryogenesis. J Mol Histol. 2008 Feb;39(1):95-103
18*	J:141032 Yon JM, Baek IJ, Lee SR, Kim MR, Lee BJ, Yun YW, Nam SY, Immunohistochemical identification and quantitative analysis of cytoplasmic Cu/Zn superoxide dismutase in mouse organogenesis. J Vet Sci. 2008 Sep;9(3):233-40
1*	J:334015 Yoshioka H, Komura S, Kuramitsu N, Goto A, Hasegawa T, Amizuka N, Ishimoto T, Ozasa R, Nakano T, Imai Y, Akiyama H, Deletion of Tfam in Prx1-Cre expressing limb mesenchyme results in spontaneous bone fractures. J Bone Miner Metab. 2022 Sep;40(5):839-852
6	J:296376 Zhao H, Narasimhan P, Kalish F, Wong RJ, Stevenson DK, Dysregulation of hypoxia-inducible factor-1alpha (Hif1alpha) expression in the Hmox1-deficient placenta. Placenta. 2020 Sep 15;99:108-116
4	J:342401 Zhao H, Wong RJ, Stevenson DK, The placental vasculature is affected by changes in gene expression and glycogen-rich cells in a diet-induced obesity mouse model. PLoS One. 2023;18(11):e0294185
1*	J:229263 Zhu J, Hou Q, Dong XD, Wang Z, Chen X, Zheng D, Zhou L, He C, Liu M, Tu L, Qu J, Targeted deletion of the murine Lgr4 gene decreases lens epithelial cell resistance to oxidative stress and induces age-related cataract formation. PLoS One. 2015;10(3):e0119599