Gene Expression Literature Summary

• Symbol: Tcf4
• Name: transcription factor 4
• ID: MGI:98506

75 matching records from 75 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E1.5	E2	E2.5	E3	E3.5	E4.5	E7	E8.5	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19.5	E	P
Immunohistochemistry (section)													2	1	2		2	1	2		3		1		1		3			5
In situ RNA (section)								1		1	2		4	1	5		7	2	11		10	1	2		3	1	5		2	11
In situ RNA (whole mount)								1	3	1	2		1								2
In situ reporter (knock in)																														2
Northern blot							1		1	1	1		1			1	1				1	1			1	1		1	2	3
Western blot														2			1	1	2		1		1		1	1	3			5
RT-PCR	2	2	1	1	1	1					1	1		2	2	1	1	2	3	1	2	2	2	1	2	3	3	1		11
cDNA clones									1		1	1			1										1					2

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tcf4  transcription factor 4   (Synonyms: 5730422P05Rik, ASP-I2, bHLHb19, E2-2, E2.2, ITF-2, ITF-2b, ME2, MITF-2A, MITF-2B, SEF-2, SEF2-1, TFE)
Results	Reference
3	J:262618 Aldeiri B, Roostalu U, Albertini A, Behnsen J, Wong J, Morabito A, Cossu G, Abrogation of TGF-beta signalling in TAGLN expressing cells recapitulates Pentalogy of Cantrell in the mouse. Sci Rep. 2018 Feb 26;8(1):3658
1*	J:178848 An CI, Dong Y, Hagiwara N, Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6. BMC Dev Biol. 2011;11:59
2	J:112701 Bailey PJ, Klos JM, Andersson E, Karlen M, Kallstrom M, Ponjavic J, Muhr J, Lenhard B, Sandelin A, Ericson J, A global genomic transcriptional code associated with CNS-expressed genes. Exp Cell Res. 2006 Oct 1;312(16):3108-19
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
1*	J:302571 Casingal CR, Kikkawa T, Inada H, Sasaki Y, Osumi N, Identification of FMRP target mRNAs in the developmental brain: FMRP might coordinate Ras/MAPK, Wnt/beta-catenin, and mTOR signaling during corticogenesis. Mol Brain. 2020 Dec 16;13(1):167
1	J:341393 Cheffer A, Garcia-Miralles M, Maier E, Akol I, Franz H, Srinivasan VSV, Vogel T, DOT1L deletion impairs the development of cortical parvalbumin-expressing interneurons. Cereb Cortex. 2023 Sep 26;33(19):10272-10285
1	J:38665 Chen B, Lim RW, Physical and functional interactions between the transcriptional inhibitors Id3 and ITF-2b. Evidence toward a novel mechanism regulating muscle-specific gene expression. J Biol Chem. 1997 Jan 24;272(4):2459-63
3	J:354662 Chen HY, Phan BN, Shim G, Hamersky GR, Sadowski N, O'Donnell TS, Sripathy SR, Bohlen JF, Pfenning AR, Maher BJ, Psychiatric risk gene Transcription Factor 4 (TCF4) regulates the density and connectivity of distinct inhibitory interneuron subtypes. Mol Psychiatry. 2023 Nov;28(11):4679-4692
7*	J:316102 Chen T, Wu Q, Zhang Y, Lu T, Yue W, Zhang D, Tcf4 Controls Neuronal Migration of the Cerebral Cortex through Regulation of Bmp7. Front Mol Neurosci. 2016;9:94
1	J:284605 Coquenlorge S, Yin WC, Yung T, Pan J, Zhang X, Mo R, Belik J, Hui CC, Kim TH, GLI2 Modulated by SUFU and SPOP Induces Intestinal Stem Cell Niche Signals in Development and Tumorigenesis. Cell Rep. 2019 Jun 4;27(10):3006-3018.e4
1	J:189513 Crespo-Enriquez I, Partanen J, Martinez S, Echevarria D, Fgf8-related secondary organizers exert different polarizing planar instructions along the mouse anterior neural tube. PLoS One. 2012;7(7):e39977
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:196080 Elsen GE, Hodge RD, Bedogni F, Daza RA, Nelson BR, Shiba N, Reiner SL, Hevner RF, The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4081-6
1	J:183190 Fehrenschild D, Galli U, Breiden B, Bloch W, Schettina P, Brodesser S, Michels C, Gunschmann C, Sandhoff K, Niessen CM, Niemann C, TCF/Lef1-mediated control of lipid metabolism regulates skin barrier function. J Invest Dermatol. 2012 Feb;132(2):337-45
2	J:125313 Flora A, Garcia JJ, Thaller C, Zoghbi HY, The E-protein Tcf4 interacts with Math1 to regulate differentiation of a specific subset of neuronal progenitors. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15382-7
1*	J:152838 Fu H, Cai J, Clevers H, Fast E, Gray S, Greenberg R, Jain MK, Ma Q, Qiu M, Rowitch DH, Taylor CM, Stiles CD, A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development. J Neurosci. 2009 Sep 9;29(36):11399-408
1	J:152858 Garcia-Ortiz JE, Pelosi E, Omari S, Nedorezov T, Piao Y, Karmazin J, Uda M, Cao A, Cole SW, Forabosco A, Schlessinger D, Ottolenghi C, Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Dev Biol. 2009;9:36
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
7*	J:140465 Guo G, Huss M, Tong GQ, Wang C, Li Sun L, Clarke ND, Robson P, Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Dev Cell. 2010 Apr 20;18(4):675-85
1	J:142415 Hoffman BG, Zavaglia B, Beach M, Helgason CD, Expression of Groucho/TLE proteins during pancreas development. BMC Dev Biol. 2008;8:81
1	J:256001 Jung EM, Moffat JJ, Liu J, Dravid SM, Gurumurthy CB, Kim WY, Arid1b haploinsufficiency disrupts cortical interneuron development and mouse behavior. Nat Neurosci. 2017 Dec;20(12):1694-1707
5	J:265025 Jung M, Haberle BM, Tschaikowsky T, Wittmann MT, Balta EA, Stadler VC, Zweier C, Dorfler A, Gloeckner CJ, Lie DC, Analysis of the expression pattern of the schizophrenia-risk and intellectual disability gene TCF4 in the developing and adult brain suggests a role in development and plasticity of cortical and hippocampal neurons. Mol Autism. 2018;9:20
1	J:181994 Kamileri I, Karakasilioti I, Sideri A, Kosteas T, Tatarakis A, Talianidis I, Garinis GA, Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2995-3000
3*	J:331303 Kantzer CG, Yang W, Grommisch D, Patikl KV, Mak KH, Shirokova V, Genander M, ID1 and CEBPA coordinate epidermal progenitor cell differentiation. Development. 2022 Nov;149(22)
5	J:308040 Kim H, Berens NC, Ochandarena NE, Philpot BD, Region and Cell Type Distribution of TCF4 in the Postnatal Mouse Brain. Front Neuroanat. 2020;14:42
4	J:324531 Kim H, Gao EB, Draper A, Berens NC, Vihma H, Zhang X, Higashi-Howard A, Ritola KD, Simon JM, Kennedy AJ, Philpot BD, Rescue of behavioral and electrophysiological phenotypes in a Pitt-Hopkins syndrome mouse model by genetic restoration of Tcf4 expression. Elife. 2022 May 10;11:e72290
1*	J:321365 Knoedler JR, Inoue S, Bayless DW, Yang T, Tantry A, Davis CH, Leung NY, Parthasarathy S, Wang G, Alvarado M, Rizvi AH, Fenno LE, Ramakrishnan C, Deisseroth K, Shah NM, A functional cellular framework for sex and estrous cycle-dependent gene expression and behavior. Cell. 2022 Feb 17;185(4):654-671.e22
2	J:117793 Kudo LC, Karsten SL, Chen J, Levitt P, Geschwind DH, Genetic analysis of anterior-posterior expression gradients in the developing mammalian forebrain. Cereb Cortex. 2007 Sep;17(9):2108-22
1*	J:321499 Lee DR, Rhodes C, Mitra A, Zhang Y, Maric D, Dale RK, Petros TJ, Transcriptional heterogeneity of ventricular zone cells in the ganglionic eminences of the mouse forebrain. Elife. 2022 Feb 17;11:e71864
2*	J:116586 Li H, Bishop KM, O'Leary DD, Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning. Mol Cell Neurosci. 2006 Oct;33(2):136-49
15	J:299678 Li H, Zhu Y, Morozov YM, Chen X, Page SC, Rannals MD, Maher BJ, Rakic P, Disruption of TCF4 regulatory networks leads to abnormal cortical development and mental disabilities. Mol Psychiatry. 2019 Aug;24(8):1235-1246
1	J:109564 Li MZ, Wang JS, Jiang DJ, Xiang CX, Wang FY, Zhang KH, Williams PR, Chen ZF, Molecular mapping of developing dorsal horn-enriched genes by microarray and dorsal/ventral subtractive screening. Dev Biol. 2006 Apr 15;292(2):555-64
2	J:185188 Li S, Mattar P, Zinyk D, Singh K, Chaturvedi CP, Kovach C, Dixit R, Kurrasch DM, Ma YC, Chan JA, Wallace V, Dilworth FJ, Brand M, Schuurmans C, GSK3 Temporally Regulates Neurogenin 2 Proneural Activity in the Neocortex. J Neurosci. 2012 Jun 6;32(23):7791-805
1	J:293699 Lin JI, Feinstein TN, Jha A, McCleary JT, Xu J, Arrigo AB, Rong G, Maclay LM, Ridge T, Xu X, Lo CW, Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening. Commun Biol. 2020 Jun 16;3(1):312
2	J:305040 Lin L, Xu W, Li Y, Zhu P, Yuan W, Liu M, Shi Y, Chen Y, Liang J, Chen J, Yang B, Cai W, Wen Y, Zhu X, Peng X, Zhou Z, Mo X, Wan Y, Yuan H, Li F, Ye X, Jiang Z, Zhuang J, Wang Y, Wu X, Fan X, Pygo1 regulates pathological cardiac hypertrophy via a beta-catenin-dependent mechanism. Am J Physiol Heart Circ Physiol. 2021 Feb 26;320(4)
3*	J:302850 Liu M, Chen L, Ma NF, Chow RK, Li Y, Song Y, Chan TH, Fang S, Yang X, Xi S, Jiang L, Li Y, Zeng TT, Li Y, Yuan YF, Guan XY, CHD1L promotes lineage reversion of hepatocellular carcinoma through opening chromatin for key developmental transcription factors. Hepatology. 2016 May;63(5):1544-59
1*	J:311994 Livnat I, Finkelshtein D, Ghosh I, Arai H, Reiner O, PAF-AH Catalytic Subunits Modulate the Wnt Pathway in Developing GABAergic Neurons. Front Cell Neurosci. 2010;4
1*	J:173286 Long JE, Cobos I, Potter GB, Rubenstein JL, Dlx1&2 and Mash1 transcription factors control MGE and CGE patterning and differentiation through parallel and overlapping pathways. Cereb Cortex. 2009 Jul;19 Suppl 1:i96-106
1*	J:103132 Lorenzen JA, Bonacci BB, Palmer RE, Wells C, Zhang J, Haber DA, Goldstein AM, Mayer AN, Rbm19 is a nucleolar protein expressed in crypt/progenitor cells of the intestinal epithelium. Gene Expr Patterns. 2005 Dec;6(1):45-56
4	J:301718 Lowenstein ED, Rusanova A, Stelzer J, Hernaiz-Llorens M, Schroer AE, Epifanova E, Bladt F, Isik EG, Buchert S, Jia S, Tarabykin V, Hernandez-Miranda LR, Olig3 regulates early cerebellar development. Elife. 2021 Feb 16;10:e64684
1	J:283040 McKenzie MG, Cobbs LV, Dummer PD, Petros TJ, Halford MM, Stacker SA, Zou Y, Fishell GJ, Au E, Non-canonical Wnt Signaling through Ryk Regulates the Generation of Somatostatin- and Parvalbumin-Expressing Cortical Interneurons. Neuron. 2019 Sep 4;103(5):853-864.e4
4*	J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636
7	J:306233 Mesman S, Bakker R, Smidt MP, Tcf4 is required for correct brain development during embryogenesis. Mol Cell Neurosci. 2020 Jul;106:103502
2	J:92533 Murakami M, Kataoka K, Tominaga J, Nakagawa O, Kurihara H, Differential cooperation between dHAND and three different E-proteins. Biochem Biophys Res Commun. 2004 Oct 8;323(1):168-174
1	J:295059 Patel MM, Behar AR, Silasi R, Regmi G, Sansam CL, Keshari RS, Lupu F, Lupu C, Role of ADTRP (Androgen-Dependent Tissue Factor Pathway Inhibitor Regulating Protein) in Vascular Development and Function. J Am Heart Assoc. 2018 Nov 20;7(22):e010690
1	J:269416 Pensold D, Symmank J, Hahn A, Lingner T, Salinas-Riester G, Downie BR, Ludewig F, Rotzsch A, Haag N, Andreas N, Schubert K, Hubner CA, Pieler T, Zimmer G, The DNA Methyltransferase 1 (DNMT1) Controls the Shape and Dynamics of Migrating POA-Derived Interneurons Fated for the Murine Cerebral Cortex. Cereb Cortex. 2017 Dec 1;27(12):5696-5714
8	J:292770 Phan BN, Bohlen JF, Davis BA, Ye Z, Chen HY, Mayfield B, Sripathy SR, Cerceo Page S, Campbell MN, Smith HL, Gallop D, Kim H, Thaxton CL, Simon JM, Burke EE, Shin JH, Kennedy AJ, Sweatt JD, Philpot BD, Jaffe AE, Maher BJ, A myelin-related transcriptomic profile is shared by Pitt-Hopkins syndrome models and human autism spectrum disorder. Nat Neurosci. 2020 Mar;23(3):375-385
9*	J:38018 Pscherer A, Dorflinger U, Kirfel J, Gawlas K, Ruschoff J, Buettner R, Schule R, The helix-loop-helix transcription factor SEF-2 regulates the activity of a novel initiator element in the promoter of the human somatostatin receptor II gene. EMBO J. 1996 Dec 2;15(23):6680-90
1	J:239349 Rannals MD, Hamersky GR, Page SC, Campbell MN, Briley A, Gallo RA, Phan BN, Hyde TM, Kleinman JE, Shin JH, Jaffe AE, Weinberger DR, Maher BJ, Psychiatric Risk Gene Transcription Factor 4 Regulates Intrinsic Excitability of Prefrontal Neurons via Repression of SCN10a and KCNQ1. Neuron. 2016 Apr 06;90(1):43-55
6	J:134786 Ravanpay AC, Olson JM, E protein dosage influences brain development more than family member identity. J Neurosci Res. 2008 May 15;86(7):1472-81
3	J:335660 Scott IC, Anson-Cartwright L, Riley P, Reda D, Cross JC, The HAND1 basic helix-loop-helix transcription factor regulates trophoblast differentiation via multiple mechanisms. Mol Cell Biol. 2000 Jan;20(2):530-41
3	J:109567 Shen WB, Plachez C, Mongi AS, Richards LJ, Identification of candidate genes at the corticoseptal boundary during development. Gene Expr Patterns. 2006 Jun;6(5):471-81
4	J:331470 Sirp A, Shubina A, Tuvikene J, Tamberg L, Kiir CS, Kranich L, Timmusk T, Expression of alternative transcription factor 4 mRNAs and protein isoforms in the developing and adult rodent and human tissues. Front Mol Neurosci. 2022;15:1033224
3	J:150518 Sobrado VR, Moreno-Bueno G, Cubillo E, Holt LJ, Nieto MA, Portillo F, Cano A, The class I bHLH factors E2-2A and E2-2B regulate EMT. J Cell Sci. 2009 Apr 1;122(Pt 7):1014-24
5	J:20051 Soosaar A, Chiaramello A, Zuber MX, Neuman T, Expression of basic-helix-loop-helix transcription factor ME2 during brain development and in the regions of neuronal plasticity in the adult brain. Brain Res Mol Brain Res. 1994 Aug;25(1-2):176-80
1	J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020
7	J:340405 Talley MJ, Nardini D, Ehrman LA, Lu QR, Waclaw RR, Distinct requirements for Tcf3 and Tcf12 during oligodendrocyte development in the mouse telencephalon. Neural Dev. 2023 Sep 8;18(1):5
1	J:270543 Tanahashi H, Suzuki T, Deletion of Lrp4 increases the incidence of microphthalmia. Biochem Biophys Res Commun. 2018 Nov 30;506(3):478-484
2*	J:174767 Tang F, Barbacioru C, Nordman E, Bao S, Lee C, Wang X, Tuch BB, Heard E, Lao K, Surani MA, Deterministic and stochastic allele specific gene expression in single mouse blastomeres. PLoS One. 2011;6(6):e21208
5*	J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23
1	J:270598 Tiklova K, Bjorklund AK, Lahti L, Fiorenzano A, Nolbrant S, Gillberg L, Volakakis N, Yokota C, Hilscher MM, Hauling T, Holmstrom F, Joodmardi E, Nilsson M, Parmar M, Perlmann T, Single-cell RNA sequencing reveals midbrain dopamine neuron diversity emerging during mouse brain development. Nat Commun. 2019 Feb 4;10(1):581
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
8	J:316579 Wang Y, Lu Z, Zhang Y, Cai Y, Yun D, Tang T, Cai Z, Wang C, Zhang Y, Fang F, Yang Z, Behnisch T, Xie Y, Transcription Factor 4 Safeguards Hippocampal Dentate Gyrus Development by Regulating Neural Progenitor Migration. Cereb Cortex. 2020 May 14;30(5):3102-3115
1*	J:288669 Wedel M, Frob F, Elsesser O, Wittmann MT, Lie DC, Reis A, Wegner M, Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation. Nucleic Acids Res. 2020 May 21;48(9):4839-4857
1*	J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
1	J:163602 Witte F, Chan D, Economides AN, Mundlos S, Stricker S, Receptor tyrosine kinase-like orphan receptor 2 (ROR2) and Indian hedgehog regulate digit outgrowth mediated by the phalanx-forming region. Proc Natl Acad Sci U S A. 2010 Aug 10;107(32):14211-6
2	J:308798 Wittmann MT, Katada S, Sock E, Kirchner P, Ekici AB, Wegner M, Nakashima K, Lie DC, Reis A, scRNA sequencing uncovers a TCF4-dependent transcription factor network regulating commissure development in mouse. Development. 2021 Jul 15;148(14):dev196022
3*	J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
1	J:62914 Yoon JK, Moon RT, Wold B, The bHLH class protein pMesogenin1 can specify paraxial mesoderm phenotypes. Dev Biol. 2000 Jun 15;222(2):376-91
1	J:319920 Ypsilanti AR, Pattabiraman K, Catta-Preta R, Golonzhka O, Lindtner S, Tang K, Jones IR, Abnousi A, Juric I, Hu M, Shen Y, Dickel DE, Visel A, Pennachio LA, Hawrylycz M, Thompson CL, Zeng H, Barozzi I, Nord AS, Rubenstein JL, Transcriptional network orchestrating regional patterning of cortical progenitors. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2024795118
1	J:280702 Yung T, Poon F, Liang M, Coquenlorge S, McGaugh EC, Hui CC, Wilson MD, Nostro MC, Kim TH, Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals. Nat Commun. 2019 Oct 11;10(1):4647
1	J:313963 Zhang Y, Cai Y, Wang Y, Deng X, Zhao Y, Zhang Y, Xie Y, Survival control of oligodendrocyte progenitor cells requires the transcription factor 4 during olfactory bulb development. Cell Death Dis. 2021 Jan 18;12(1):91
1	J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687
1*	J:22134 Zhuang Y, Soriano P, Weintraub H, The helix-loop-helix gene E2A is required for B cell formation. Cell. 1994 Dec 2;79(5):875-84