Gene Expression Literature Summary

• Symbol: Tpm2
• Name: tropomyosin 2, beta
• ID: MGI:98810

18 matching records from 18 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E8.5	E9.5	E10	E11	E11.5	E12	E13	E14	E14.5	E15	E15.5	E16	E16.5	E18	E18.5	E	P
Immunohistochemistry (section)													1
In situ RNA (section)									1		3	1	1	1	1		3
In situ RNA (whole mount)	1	1
Northern blot																	1
Western blot																	2
RT-PCR					1								1		1	1	7
cDNA clones		1							1
RNase protection			1	1		1	1	1		1		1					1
Nuclease S1																1	1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tpm2  tropomyosin 2, beta   (Synonyms: Tpm-2, Trop-2)
Results	Reference
3*	J:93300 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL, Genomic analysis of mouse retinal development. PLoS Biol. 2004 Oct;2(9):E247
1*	J:44952 Blanchard EM, Iizuka K, Christe M, Conner DA, Geisterfer-Lowrance A, Schoen FJ, Maughan DW, Seidman CE, Seidman JG, Targeted ablation of the murine alpha-tropomyosin gene. Circ Res. 1997 Dec;81(6):1005-10
1	J:33282 Chevray PM, Nathans D, Protein interaction cloning in yeast: identification of mammalian proteins that react with the leucine zipper of Jun. Proc Natl Acad Sci U S A. 1992 Jul 1;89(13):5789-93
2	J:291994 de Groot NE, van den Hoogenhof MMG, Najafi A, van der Made I, van der Velden J, Beqqali A, Pinto YM, Creemers EE, Heterozygous loss of Rbm24 in the adult mouse heart increases sarcomere slack length but does not affect function. Sci Rep. 2020 May 6;10(1):7687
1*	J:276652 Fang Q, Zhang Y, Da P, Shao B, Pan H, He Z, Cheng C, Li D, Guo J, Wu X, Guan M, Liao M, Zhang Y, Sha S, Zhou Z, Wang J, Wang T, Su K, Chai R, Chen F, Deletion of Limk1 and Limk2 in mice does not alter cochlear development or auditory function. Sci Rep. 2019 Mar 4;9(1):3357
1	J:324468 Gan P, Wang Z, Morales MG, Zhang Y, Bassel-Duby R, Liu N, Olson EN, RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development. Dev Cell. 2022 Apr 25;57(8):959-973.e7
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:213153 Harms MJ, Ishibashi J, Wang W, Lim HW, Goyama S, Sato T, Kurokawa M, Won KJ, Seale P, Prdm16 is required for the maintenance of brown adipocyte identity and function in adult mice. Cell Metab. 2014 Apr 1;19(4):593-604
1	J:108465 Issa LL, Palmer SJ, Guven KL, Santucci N, Hodgson VR, Popovic K, Joya JE, Hardeman EC, MusTRD can regulate postnatal fiber-specific expression. Dev Biol. 2006 May 1;293(1):104-15
7*	J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735
1	J:347631 Li C, Zhang Y, Shen J, Bao H, Zhao Y, Li D, Li S, Liu Y, Yang J, Zhou Z, Gao K, Zhao L, Pei Y, Lu Y, Pan Z, Cai B, Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes. Adv Sci (Weinh). 2024 Mar;11(11):e2305992
4	J:11851 Muthuchamy M, Pajak L, Howles P, Doetschman T, Wieczorek DF, Developmental analysis of tropomyosin gene expression in embryonic stem cells and mouse embryos. Mol Cell Biol. 1993 Jun;13(6):3311-23
1*	J:97059 Nassar R, Malouf NN, Mao L, Rockman HA, Oakeley AE, Frye JR, Herlong JR, Sanders SP, Anderson PA, cTnT1, a cardiac troponin T isoform, decreases myofilament tension and affects the left ventricular pressure waveform. Am J Physiol Heart Circ Physiol. 2005 Mar;288(3):H1147-56
2	J:65651 Neidhardt L, Gasca S, Wertz K, Obermayr F, Worpenberg S, Lehrach H, Herrmann BG, Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. Mech Dev. 2000 Nov;98(1-2):77-94
1*	J:161404 Stevens J, Ermakov A, Braganca J, Hilton H, Underhill P, Bhattacharya S, Brown NA, Norris DP, Analysis of the asymmetrically expressed Ablim1 locus reveals existence of a lateral plate Nodal-independent left sided signal and an early, left-right independent role for nodal flow. BMC Dev Biol. 2010;10:54
1	J:171050 Thiagarajan RD, Georgas KM, Rumballe BA, Lesieur E, Chiu HS, Taylor D, Tang DT, Grimmond SM, Little MH, Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS One. 2011;6(2):e17286
2	J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28
8	J:1405 Wang YC, Rubenstein PA, Splicing of two alternative exon pairs in beta-tropomyosin pre-mRNA is independently controlled during myogenesis. J Biol Chem. 1992 Jun 15;267(17):12004-10