Gene Expression Literature Summary

• Symbol: Tyrp1
• Name: tyrosinase-related protein 1
• ID: MGI:98881

24 matching records from 24 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E10	E11.5	E12.5	E13.5	E14	E14.5	E15.5	E16	E17.5	E18.5	E20	P
Immunohistochemistry (section)		1		1	2		2	1	1	1	1	3
In situ RNA (section)	1	1	2	1		4						1
In situ RNA (whole mount)		2
Western blot												2
RT-PCR							2					5

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tyrp1  tyrosinase-related protein 1   (Synonyms: isa, Oca3, TRP-1, TRP1, Tyrp)
Results	Reference
1	J:194534 Chang CY, Pasolli HA, Giannopoulou EG, Guasch G, Gronostajski RM, Elemento O, Fuchs E, NFIB is a governor of epithelial-melanocyte stem cell behaviour in a shared niche. Nature. 2013 Mar 7;495(7439):98-102
1	J:333926 Chen Y, Wu C, Peng S, Guo D, Ouyang H, Wei Y, Ju R, Ding X, Xie Z, Liu C, Single-Cell Characterization of the Frizzled 5 (Fz5) Mutant Mouse and Human Persistent Fetal Vasculature (PFV). Invest Ophthalmol Vis Sci. 2023 Mar 1;64(3):8
1	J:239862 Coram RJ, Stillwagon SJ, Guggilam A, Jenkins MW, Swanson MS, Ladd AN, Muscleblind-like 1 is required for normal heart valve development in vivo. BMC Dev Biol. 2015 Oct 15;15:36
1	J:211299 Denecker G, Vandamme N, Akay O, Koludrovic D, Taminau J, Lemeire K, Gheldof A, De Craene B, Van Gele M, Brochez L, Udupi GM, Rafferty M, Balint B, Gallagher WM, Ghanem G, Huylebroeck D, Haigh J, van den Oord J, Larue L, Davidson I, Marine JC, Berx G, Identification of a ZEB2-MITF-ZEB1 transcriptional network that controls melanogenesis and melanoma progression. Cell Death Differ. 2014 Aug;21(8):1250-61
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1	J:94374 Horsford DJ, Nguyen MT, Sellar GC, Kothary R, Arnheiter H, McInnes RR, Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity. Development. 2005 Jan;132(1):177-87
4	J:315293 Kumamoto T, Toma K, Gunadi, McKenna WL, Kasukawa T, Katzman S, Chen B, Hanashima C, Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013 Mar 28;3(3):931-45
1	J:101313 Lanning JL, Wallace JS, Zhang D, Diwakar G, Jiao Z, Hornyak TJ, Altered melanocyte differentiation and retinal pigmented epithelium transdifferentiation induced by Mash1 expression in pigment cell precursors. J Invest Dermatol. 2005 Oct;125(4):805-17
1	J:100591 Lee HY, Wroblewski E, Philips GT, Stair CN, Conley K, Reedy M, Mastick GS, Brown NL, Multiple requirements for Hes 1 during early eye formation. Dev Biol. 2005 Aug 15;284(2):464-78
1	J:154593 Levin MD, Lu MM, Petrenko NB, Hawkins BJ, Gupta TH, Lang D, Buckley PT, Jochems J, Liu F, Spurney CF, Yuan LJ, Jacobson JT, Brown CB, Huang L, Beermann F, Margulies KB, Madesh M, Eberwine JH, Epstein JA, Patel VV, Melanocyte-like cells in the heart and pulmonary veins contribute to atrial arrhythmia triggers. J Clin Invest. 2009 Nov;119(11):3420-36
1*	J:157352 Loftus SK, Baxter LL, Buac K, Watkins-Chow DE, Larson DM, Pavan WJ, Comparison of melanoblast expression patterns identifies distinct classes of genes. Pigment Cell Melanoma Res. 2009 Oct;22(5):611-22
1*	J:75774 Loftus SK, Larson DM, Baxter LL, Antonellis A, Chen Y, Wu X, Jiang Y, Bittner M, Hammer JA 3rd, Pavan WJ, Mutation of melanosome protein RAB38 in chocolate mice. Proc Natl Acad Sci U S A. 2002 Apr 2;99(7):4471-6
2	J:169528 Manceau M, Domingues VS, Mallarino R, Hoekstra HE, The developmental role of Agouti in color pattern evolution. Science. 2011 Feb 25;331(6020):1062-5
1*	J:46130 Nakayama A, Nguyen MT, Chen CC, Opdecamp K, Hodgkinson CA, Arnheiter H, Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently. Mech Dev. 1998 Jan;70(1-2):155-66
1*	J:96883 Olson LE, Zhang J, Taylor H, Rose DW, Rosenfeld MG, Barx2 functions through distinct corepressor classes to regulate hair follicle remodeling. Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3708-13
2	J:226887 Raviv S, Bharti K, Rencus-Lazar S, Cohen-Tayar Y, Schyr R, Evantal N, Meshorer E, Zilberberg A, Idelson M, Reubinoff B, Grebe R, Rosin-Arbesfeld R, Lauderdale J, Lutty G, Arnheiter H, Ashery-Padan R, PAX6 regulates melanogenesis in the retinal pigmented epithelium through feed-forward regulatory interactions with MITF. PLoS Genet. 2014;10(5):e1004360
1	J:325352 Sahut-Barnola I, Lefrancois-Martinez AM, Dufour D, Botto JM, Kamilaris C, Faucz FR, Stratakis CA, Val P, Martinez A, Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome. J Invest Dermatol. 2022 May 12;
3	J:229511 Son AI, Sheleg M, Cooper MA, Sun Y, Kleiman NJ, Zhou R, Formation of persistent hyperplastic primary vitreous in ephrin-A5-/- mice. Invest Ophthalmol Vis Sci. 2014 Mar;55(3):1594-606
3*	J:31646 Steel KP, Davidson DR, Jackson IJ, TRP-2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor. Development. 1992 Aug;115(4):1111-9
1	J:34022 Takayama H, La Rochelle WJ, Anver M, Bockman DE, Merlino G, Scatter factor/hepatocyte growth factor as a regulator of skeletal muscle and neural crest development. Proc Natl Acad Sci U S A. 1996 Jun 11;93(12):5866-71
2	J:282279 Ustun Y, Reibetanz M, Brachvogel B, Nischt R, Eckes B, Zigrino P, Krieg T, Dual role of laminin511 in regulating melanocyte migration and differentiation. Matrix Biol. 2019 Jul;80:59-71
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1	J:53380 Wawersik S, Purcell P, Rauchman M, Dudley AT, Robertson EJ, Maas R, BMP7 acts in murine lens placode development. Dev Biol. 1999 Mar 1;207(1):176-88
1*	J:279788 Wen B, Li S, Li H, Chen Y, Ma X, Wang J, Lu F, Qu J, Hou L, Microphthalmia-associated transcription factor regulates the visual cycle genes Rlbp1 and Rdh5 in the retinal pigment epithelium. Sci Rep. 2016 Feb 15;6:21208