Symbol Name ID |
Pcgf2
polycomb group ring finger 2 MGI:99161 |
Age | E0.5 | E1 | E2 | E2.5 | E3 | E3.5 | E8.5 | E10.5 | E11.5 | E12.5 | E13.5 | E14.5 | E15 | E15.5 | E16.5 | E17.5 | E18.5 | P |
Immunohistochemistry (section) | 1 | |||||||||||||||||
In situ RNA (section) | 1 | 3 | 1 | |||||||||||||||
Immunohistochemistry (whole mount) | 1 | |||||||||||||||||
In situ RNA (whole mount) | 1 | 2 | ||||||||||||||||
In situ reporter (knock in) | 1 | |||||||||||||||||
Northern blot | 1 | 1 | 2 | 1 | 1 | 1 | 1 | 1 | 1 | |||||||||
Western blot | 1 | |||||||||||||||||
RT-PCR | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 3 | |||||||
cDNA clones | 1 | 1 | ||||||||||||||||
RNase protection | 1 | 1 |
Pcgf2 polycomb group ring finger 2 (Synonyms: mel-18, Mel18, Rnf110, Zfp144) | |
Results | Reference |
2* | J:33159 Akasaka T, Kanno M, Balling R, Mieza MA, Taniguchi M, Koseki H, A role for mel-18, a Polycomb group-related vertebrate gene, during the anteroposterior specification of the axial skeleton. Development. 1996 MAY;122(5):1513-1522 |
9* | J:38105 Alkema MJ, Bronk M, Verhoeven E, Otte A, van't Veer LJ, Berns A, van Lohuizen M, Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian polycomb complex. Genes Dev. 1997 Jan 15;11(2):226-40 |
1* | J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034 |
2 | J:338403 Cho KW, Andrade M, Bae S, Kim S, Eyun Kim J, Jang EY, Lee S, Husain A, Sutliff RL, Calvert JW, Park C, Yoon YS, Polycomb Group Protein CBX7 Represses Cardiomyocyte Proliferation Through Modulation of the TARDBP/RBM38 Axis. Circulation. 2023 Jun 13;147(24):1823-1842 |
1* | J:266522 Elsen GE, Bedogni F, Hodge RD, Bammler TK, MacDonald JW, Lindtner S, Rubenstein JLR, Hevner RF, The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6--> Tbr2--> Tbr1. Front Neurosci. 2018;12:571 |
1* | J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1 | J:225041 Hasegawa K, Sin HS, Maezawa S, Broering TJ, Kartashov AV, Alavattam KG, Ichijima Y, Zhang F, Bacon WC, Greis KD, Andreassen PR, Barski A, Namekawa SH, SCML2 establishes the male germline epigenome through regulation of histone H2A ubiquitination. Dev Cell. 2015 Mar 9;32(5):574-88 |
1 | J:96358 Isono K, Mizutani-Koseki Y, Komori T, Schmidt-Zachmann MS, Koseki H, Mammalian polycomb-mediated repression of Hox genes requires the essential spliceosomal protein Sf3b1. Genes Dev. 2005 Mar 1;19(5):536-41 |
1 | J:79790 Kleiter N, Artner I, Gmachl N, Ghaffari-Tabrizi N, Kratochwil K, Mutagenic transgene insertion into a region of high gene density and multiple linkage disruptions on mouse chromosome 11. Cytogenet Genome Res. 2002;97(1-2):100-5 |
4 | J:75968 Koga H, Kaji Y, Nishii K, Shirai M, Tomotsune D, Osugi T, Sawada A, Kim JY, Hara J, Miwa T, Yamauchi-Takihara K, Shibata Y, Takihara Y, Overexpression of Polycomb-group gene rae28 in cardiomyocytes does not complement abnormal cardiac morphogenesis in mice lacking rae28 but causes dilated cardiomyopathy. Lab Invest. 2002 Apr;82(4):375-85 |
1* | J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9 |
1 | J:152848 Martinez-Romero C, Rooman I, Skoudy A, Guerra C, Molero X, Gonzalez A, Iglesias M, Lobato T, Bosch A, Barbacid M, Real FX, Hernandez-Munoz I, The epigenetic regulators Bmi1 and Ring1B are differentially regulated in pancreatitis and pancreatic ductal adenocarcinoma. J Pathol. 2009 Oct;219(2):205-13 |
1* | J:138263 Miki J, Fujimura Y, Koseki H, Kamijo T, Polycomb complexes regulate cellular senescence by repression of ARF in cooperation with E2F3. Genes Cells. 2007 Dec;12(12):1371-82 |
7 | J:134477 Puschendorf M, Terranova R, Boutsma E, Mao X, Isono K, Brykczynska U, Kolb C, Otte AP, Koseki H, Orkin SH, van Lohuizen M, Peters AH, PRC1 and Suv39h specify parental asymmetry at constitutive heterochromatin in early mouse embryos. Nat Genet. 2008 Apr;40(4):411-20 |
3* | J:111614 Vogel T, Stoykova A, Gruss P, Differential expression of polycomb repression complex 1 (PRC1) members in the developing mouse brain reveals multiple complexes. Dev Dyn. 2006 Jun 19;235(9):2574-2585 |
1* | J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130 |
1 | J:194892 Yokobayashi S, Liang CY, Kohler H, Nestorov P, Liu Z, Vidal M, van Lohuizen M, Roloff TC, Peters AH, PRC1 coordinates timing of sexual differentiation of female primordial germ cells. Nature. 2013 Mar 14;495(7440):236-40 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 10/29/2024 MGI 6.24 |
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