Gene Expression Literature Summary

• Symbol: Fasl
• Name: Fas ligand
• ID: MGI:99255

24 matching records from 24 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E4.5	E5.5	E7.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14.5	E15	E15.5	E16	E16.5	E17.5	E18	E18.5	E	P
Immunohistochemistry (section)	1	2	1		2			1	1	1	1	2	2	1	1	2		1	2		2	2	5
In situ RNA (section)																		1				1
In situ RNA (whole mount)																1
Western blot		1	1	1	1	1		1	1									1			3		5
RT-PCR					1		1		1				3	2	1	3	2	1	2	1	1		3
RNase protection														1		1			1		1		3

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Fasl  Fas ligand   (Synonyms: APT1LG1, CD178, CD95L, Fasl, Fas-L, Tnfsf6)
Results	Reference
5	J:94928 De Paepe ME, Mao Q, Embree-Ku M, Rubin LP, Luks FI, Fas/FasL-mediated apoptosis in perinatal murine lungs. Am J Physiol Lung Cell Mol Physiol. 2004 Oct;287(4):L730-42
5	J:111004 Fleck M, Zhou T, Tatsuta T, Yang P, Wang Z, Mountz JD, Fas/Fas ligand signaling during gestational T cell development. J Immunol. 1998 Apr 15;160(8):3766-75
3*	J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
6	J:32512 French LE, Hahne M, Viard I, Radlgruber G, Zanone R, Becker K, Muller C, Tschopp J, Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover. J Cell Biol. 1996 Apr;133(2):335-43
1*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
19*	J:39792 Hunt JS, Vassmer D, Ferguson TA, Miller L, Fas ligand is positioned in mouse uterus and placenta to prevent trafficking of activated leukocytes between the mother and the conceptus. J Immunol. 1997 May 1;158(9):4122-8
3	J:155983 Ikeda T, Kanazawa T, Otsuka S, Ichii O, Hashimoto Y, Kon Y, Expression of caspase family and muscle- and apoptosis-specific genes during skeletal myogenesis in mouse embryo. J Vet Med Sci. 2009 Sep;71(9):1161-8
3	J:84726 Joswig A, Gabriel HD, Kibschull M, Winterhager E, Apoptosis in uterine epithelium and decidua in response to implantation: evidence for two different pathways. Reprod Biol Endocrinol. 2003 May 26;1(1):44
1	J:234310 Kuo TL, Weng CC, Kuo KK, Chen CY, Wu DC, Hung WC, Cheng KH, APC haploinsufficiency coupled with p53 loss sufficiently induces mucinous cystic neoplasms and invasive pancreatic carcinoma in mice. Oncogene. 2016 Apr 28;35(17):2223-34
1*	J:240101 Lv J, Wang L, Gao Y, Ding YQ, Liu F, 5-hydroxytryptamine synthesized in the aorta-gonad-mesonephros regulates hematopoietic stem and progenitor cell survival. J Exp Med. 2017 Feb;214(2):529-545
5	J:67809 Melnick M, Chen H, Zhou Y, Jaskoll T, Embryonic mouse submandibular salivary gland morphogenesis and the TNF/TNF-R1 signal transduction pathway. Anat Rec. 2001 Mar 1;262(3):318-30
3	J:149321 Montalvo V, Gery I, Constitutive pro-apoptotic molecules are differentially expressed in the fetal and adult mouse eye. Curr Eye Res. 2009 Apr;34(4):328-32
2*	J:75884 Mu J, Kanzaki T, Si X, Tomimatsu T, Fukuda H, Fujii E, Hosono T, Murata Y, Sugimoto Y, Ichikawa A, Apoptosis and Related Proteins during Parturition in Prostaglandin F Receptor-Deficient Mice. Biochem Biophys Res Commun. 2002 Apr 5;292(3):675-81
1	J:309497 Piao X, Miura R, Miyake S, Komazawa-Sakon S, Koike M, Shindo R, Takeda J, Hasegawa A, Abe R, Nishiyama C, Mikami T, Yagita H, Uchiyama Y, Nakano H, Blockade of TNF receptor superfamily 1 (TNFR1)-dependent and TNFR1-independent cell death is crucial for normal epidermal differentiation. J Allergy Clin Immunol. 2019 Jan;143(1):213-228.e10
3	J:109774 Roy K, Kuznicki K, Wu Q, Sun Z, Bock D, Schutz G, Vranich N, Monaghan AP, The Tlx gene regulates the timing of neurogenesis in the cortex. J Neurosci. 2004 Sep 22;24(38):8333-45
2	J:91310 Sharma PR, Anderson RH, Copp AJ, Henderson DJ, Spatiotemporal analysis of programmed cell death during mouse cardiac septation. Anat Rec A Discov Mol Cell Evol Biol. 2004 Apr;277(2):355-69
2	J:314318 Svandova E, Vesela B, Lesot H, Sadoine J, Poliard A, Matalova E, FasL Modulates Expression of Mmp2 in Osteoblasts. Front Physiol. 2018;9:1314
3*	J:261957 Svandova EB, Vesela B, Lesot H, Poliard A, Matalova E, Expression of Fas, FasL, caspase-8 and other factors of the extrinsic apoptotic pathway during the onset of interdigital tissue elimination. Histochem Cell Biol. 2017 Apr;147(4):497-510
1	J:98680 van Es JH, Jay P, Gregorieff A, van Gijn ME, Jonkheer S, Hatzis P, Thiele A, van den Born M, Begthel H, Brabletz T, Taketo MM, Clevers H, Wnt signalling induces maturation of Paneth cells in intestinal crypts. Nat Cell Biol. 2005 Apr;7(4):381-6
2*	J:83651 Wakabayashi Y, Watanabe H, Inoue J, Takeda N, Sakata J, Mishima Y, Hitomi J, Yamamoto T, Utsuyama M, Niwa O, Aizawa S, Kominami R, Bcl11b is required for differentiation and survival of alphabeta T lymphocytes. Nat Immunol. 2003 Jun;4(6):533-9
1	J:261826 Wang Y, Wu B, Farrar E, Lui W, Lu P, Zhang D, Alfieri CM, Mao K, Chu M, Yang D, Xu D, Rauchman M, Taylor V, Conway SJ, Yutzey KE, Butcher JT, Zhou B, Notch-Tnf signalling is required for development and homeostasis of arterial valves. Eur Heart J. 2017 Mar 1;38(9):675-686
1*	J:341382 Wu B, Wu B, Benkaci S, Shi L, Lu P, Park T, Morrow BE, Wang Y, Zhou B, Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development. J Am Heart Assoc. 2023 Sep 19;12(18):e029683
3*	J:260330 Yang P, Li X, Xu C, Eckert RL, Reece EA, Zielke HR, Wang F, Maternal hyperglycemia activates an ASK1-FoxO3a-caspase 8 pathway that leads to embryonic neural tube defects. Sci Signal. 2013 Aug 27;6(290):ra74
2	J:110521 Zhang X, Cowan CM, Jiang X, Soo C, Miao S, Carpenter D, Wu B, Kuroda S, Ting K, Nell-1 induces acrania-like cranioskeletal deformities during mouse embryonic development. Lab Invest. 2006 Jul;86(7):633-44