Symbol Name ID |
Arf6
ARF GTPase 6 MGI:99435 |
Age | E10.5 | E11.5 | E12.5 | E13 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16.5 | E18 | E18.5 | P |
Immunohistochemistry (section) | 1 | 1 | 1 | 1 | 1 | 1 | |||||||
In situ RNA (section) | 1 | 3 | 1 | 1 | 3 | 1 | 1 | 4 | 1 | 1 | 1 | 5 | |
In situ RNA (whole mount) | 1 | ||||||||||||
Western blot | 1 | 1 | 1 | 1 | 6 | ||||||||
RT-PCR | 1 | 1 | |||||||||||
cDNA clones | 1 |
Arf6 ARF GTPase 6 | |
Results | Reference |
9* | J:166848 Akiyama M, Zhou M, Sugimoto R, Hongu T, Furuya M, Funakoshi Y, Kato M, Hasegawa H, Kanaho Y, Tissue- and development-dependent expression of the small GTPase Arf6 in mice. Dev Dyn. 2010 Dec;239(12):3416-35 |
1 | J:196665 Arvanitis DN, Behar A, Tryoen-Toth P, Bush JO, Jungas T, Vitale N, Davy A, Ephrin B1 maintains apical adhesion of neural progenitors. Development. 2013 May;140(10):2082-92 |
4* | J:286994 Chomphoo S, Sakagami H, Kondo H, Hipkaeo W, Discrete localization patterns of Arf6, and its activators EFA6A and BRAG2, and its effector PIP5kinasegamma on myofibrils of myotubes and plasma membranes of myoblasts in developing skeletal muscles of mice. Acta Histochem. 2020 Apr;122(3):151513 |
1 | J:298804 Han JS, Hino K, Li W, Reyes RV, Canales CP, Miltner AM, Haddadi Y, Sun J, Chen CY, La Torre A, Simo S, CRL5-dependent regulation of the small GTPases ARL4C and ARF6 controls hippocampal morphogenesis. Proc Natl Acad Sci U S A. 2020 Sep 15;117(37):23073-23084 |
2 | J:237778 Hara Y, Fukaya M, Hayashi K, Kawauchi T, Nakajima K, Sakagami H, ADP Ribosylation Factor 6 Regulates Neuronal Migration in the Developing Cerebral Cortex through FIP3/Arfophilin-1-dependent Endosomal Trafficking of N-cadherin. eNeuro. 2016 Jul-Aug;3(4):ENEURO.0148-16.2016 |
1* | J:224921 Hongu T, Funakoshi Y, Fukuhara S, Suzuki T, Sakimoto S, Takakura N, Ema M, Takahashi S, Itoh S, Kato M, Hasegawa H, Mochizuki N, Kanaho Y, Arf6 regulates tumour angiogenesis and growth through HGF-induced endothelial beta1 integrin recycling. Nat Commun. 2015;6:7925 |
2* | J:272623 Kinoshita-Kawada M, Hasegawa H, Hongu T, Yanagi S, Kanaho Y, Masai I, Mishima T, Chen X, Tsuboi Y, Rao Y, Yuasa-Kawada J, Wu JY, A crucial role for Arf6 in the response of commissural axons to Slit. Development. 2019 Feb 4;146(3):dev172106 |
2 | J:258238 Krey JF, Dumont RA, Wilmarth PA, David LL, Johnson KR, Barr-Gillespie PG, ELMOD1 Stimulates ARF6-GTP Hydrolysis to Stabilize Apical Structures in Developing Vestibular Hair Cells. J Neurosci. 2018 Jan 24;38(4):843-857 |
3* | J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86 |
1 | J:346136 Matsuki T, Hamada N, Ito H, Sugawara R, Iwamoto I, Nakayama A, Nagata KI, Expression analysis of type I ARF small GTPases ARF1-3 during mouse brain development. Mol Biol Rep. 2024 Jan 16;51(1):106 |
4* | J:98185 Matsuya S, Sakagami H, Tohgo A, Owada Y, Shin HW, Takeshima H, Nakayama K, Kokubun S, Kondo H, Cellular and subcellular localization of EFA6C, a third member of the EFA6 family, in adult mouse Purkinje cells. J Neurochem. 2005 May;93(3):674-85 |
2 | J:311890 Miura Y, Ngo Thai Bich V, Furuya M, Hasegawa H, Takahashi S, Katagiri N, Hongu T, Funakoshi Y, Ohbayashi N, Kanaho Y, The small G protein Arf6 expressed in keratinocytes by HGF stimulation is a regulator for skin wound healing. Sci Rep. 2017 Apr 21;7:46649 |
1 | J:110409 Sakagami H, Suzuki H, Kamata A, Owada Y, Fukunaga K, Mayanagi H, Kondo H, Distinct spatiotemporal expression of EFA6D, a guanine nucleotide exchange factor for ARF6, among the EFA6 family in mouse brain. Brain Res. 2006 Jun 6;1093(1):1-11 |
2 | J:163183 Scholz R, Berberich S, Rathgeber L, Kolleker A, Kohr G, Kornau HC, AMPA receptor signaling through BRAG2 and Arf6 critical for long-term synaptic depression. Neuron. 2010 Jun 10;66(5):768-80 |
2 | J:111404 Suzuki T, Kanai Y, Hara T, Sasaki J, Sasaki T, Kohara M, Maehama T, Taya C, Shitara H, Yonekawa H, Frohman MA, Yokozeki T, Kanaho Y, Crucial role of the small GTPase ARF6 in hepatic cord formation during liver development. Mol Cell Biol. 2006 Aug;26(16):6149-56 |
5* | J:215487 Thompson CL, Ng L, Menon V, Martinez S, Lee CK, Glattfelder K, Sunkin SM, Henry A, Lau C, Dang C, Garcia-Lopez R, Martinez-Ferre A, Pombero A, Rubenstein JL, Wakeman WB, Hohmann J, Dee N, Sodt AJ, Young R, Smith K, Nguyen TN, Kidney J, Kuan L, Jeromin A,Kaykas A, Miller J, Page D, Orta G, Bernard A, Riley Z, Smith S, Wohnoutka P, Hawrylycz MJ, Puelles L, Jones AR, A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. Neuron. 2014 Jul 16;83(2):309-23 |
1* | J:259473 Yamauchi J, Miyamoto Y, Torii T, Takashima S, Kondo K, Kawahara K, Nemoto N, Chan JR, Tsujimoto G, Tanoue A, Phosphorylation of cytohesin-1 by Fyn is required for initiation of myelination and the extent of myelination during development. Sci Signal. 2012 Sep 25;5(243):ra69 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 12/17/2024 MGI 6.24 |
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