Gene Expression Literature Summary

• Symbol: Fgb
• Name: fibrinogen beta chain
• ID: MGI:99501

16 matching records from 16 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7	E8	E8.5	E9	E9.5	E10	E12.5	E13.5	E14.5	E15.5	E16.5	E17.5	E18.5	P
Immunohistochemistry (section)	1	1		1	2	1	1	1	3	2	1	3	1	6
In situ RNA (section)									2
Immunohistochemistry (whole mount)														1
In situ reporter (knock in)														1
Western blot								1
RT-PCR			1										1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Fgb  fibrinogen beta chain   (Synonyms: 2510049G14Rik)
Results	Reference
1	J:51137 Broze GJ Jr, Tissue factor pathway inhibitor gene disruption. Blood Coagul Fibrinolysis. 1998 Mar;9 Suppl 1:S89-92
1	J:336100 Brutsch SM, Madzharova E, Pantasis S, Wustemann T, Gurri S, Steenbock H, Gazdhar A, Kuhn G, Angel P, Bellusci S, Brinckmann J, Auf dem Keller U, Werner S, Bordoli MR, Mesenchyme-derived vertebrate lonesome kinase controls lung organogenesis by altering the matrisome. Cell Mol Life Sci. 2023 Mar 15;80(4):89
3*	J:61481 Chan JC, Cornelissen I, Collen D, Ploplis VA, Castellino FJ, Combined factor VII/protein C deficiency results in intrauterine coagulopathy in mice. J Clin Invest. 2000 Apr;105(7):897-903
2	J:67398 Chan JC, Ganopolsky JG, Cornelissen I, Suckow MA, Sandoval-Cooper MJ, Brown EC, Noria F, Gailani D, Rosen ED, Ploplis VA, Castellino FJ, The characterization of mice with a targeted combined deficiency of protein c and factor XI. Am J Pathol. 2001 Feb;158(2):469-79
2	J:237076 Crosswhite PL, Podsiadlowska JJ, Curtis CD, Gao S, Xia L, Srinivasan RS, Griffin CT, CHD4-regulated plasmin activation impacts lymphovenous hemostasis and hepatic vascular integrity. J Clin Invest. 2016 Jun 01;126(6):2254-66
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
2	J:80043 Gu JM, Crawley JT, Ferrell G, Zhang F, Li W, Esmon NL, Esmon CT, Disruption of the endothelial cell protein C receptor gene in mice causes placental thrombosis and early embryonic lethality. J Biol Chem. 2002 Nov 8;277(45):43335-43
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
3*	J:65092 Ishiguro K, Kojima T, Kadomatsu K, Nakayama Y, Takagi A, Suzuki M, Takeda N, Ito M, Yamamoto K, Matsushita T, Kusugami K, Muramatsu T, Saito H, Complete antithrombin deficiency in mice results in embryonic lethality. J Clin Invest. 2000 Oct;106(7):873-8
5	J:75302 Iwaki T, Sandoval-Cooper MJ, Paiva M, Kobayashi T, Ploplis VA, Castellino FJ, Fibrinogen stabilizes placental-maternal attachment during embryonic development in the mouse. Am J Pathol. 2002 Mar;160(3):1021-34
3*	J:50527 Jalbert LR, Rosen ED, Moons L, Chan JC, Carmeliet P, Collen D , Castellino FJ, Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice. J Clin Invest. 1998 Oct 15;102(8):1481-8
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1	J:295059 Patel MM, Behar AR, Silasi R, Regmi G, Sansam CL, Keshari RS, Lupu F, Lupu C, Role of ADTRP (Androgen-Dependent Tissue Factor Pathway Inhibitor Regulating Protein) in Vascular Development and Function. J Am Heart Assoc. 2018 Nov 20;7(22):e010690
1*	J:170493 Pfister S, Jones VJ, Power M, Truisi GL, Khoo PL, Steiner KA, Kanai-Azuma M, Kanai Y, Tam PP, Loebel DA, Sox17-dependent gene expression and early heart and gut development in Sox17-deficient mouse embryos. Int J Dev Biol. 2011;55(1):45-58
2	J:44294 Rosen ED, Chan JC, Idusogie E, Clotman F, Vlasuk G, Luther T, Jalbert LR, Albrecht S, Zhong L, Lissens A, Schoonjans L, Moons L, Collen D, Castellino FJ, Carmeliet P, Mice lacking factor VII develop normally but suffer fatal perinatal bleeding. Nature. 1997 Nov 20;390(6657):290-4
2	J:157920 Zovein AC, Luque A, Turlo KA, Hofmann JJ, Yee KM, Becker MS, Fassler R, Mellman I, Lane TF, Iruela-Arispe ML, Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism. Dev Cell. 2010 Jan 19;18(1):39-51