Gene Expression Literature Summary

• Symbol: Cttn
• Name: cortactin
• ID: MGI:99695

23 matching records from 23 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E8.5	E9.5	E10	E10.5	E11.5	E12.5	E13.5	E14.5	E15.5	E16	E18.5	P
Immunohistochemistry (section)		1	1	2	1		1		1			1
In situ RNA (section)								1					2
Immunohistochemistry (whole mount)	1												1
In situ RNA (whole mount)					1	1	1			2
In situ reporter (knock in)					1								1
Western blot					1				1				2
RT-PCR									1				1
cDNA clones					1						1		1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Cttn  cortactin   (Synonyms: 1110020L01Rik, Ems1)
Results	Reference
2*	J:65296 Brouns MR, Matheson SF, Hu K, Delalle I, Caviness VS, Silver J, Bronson RT, Settleman J, The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development. Development. 2000 Nov;127(22):4891-903
1	J:38792 Chan DC, Bedford MT, Leder P, Formin binding proteins bear WWP/WW domains that bind proline-rich peptides and functionally resemble SH3 domains. EMBO J. 1996 Mar 1;15(5):1045-54
1*	J:180120 Chauhan BK, Lou M, Zheng Y, Lang RA, Balanced Rac1 and RhoA activities regulate cell shape and drive invagination morphogenesis in epithelia. Proc Natl Acad Sci U S A. 2011 Nov 8;108(45):18289-94
1*	J:157804 Corsi JM, Houbron C, Billuart P, Brunet I, Bouvree K, Eichmann A, Girault JA, Enslen H, Autophosphorylation-independent and -dependent functions of focal adhesion kinase during development. J Biol Chem. 2009 Dec 11;284(50):34769-76
1	J:58961 Esterbauer H, Oberkofler H, Krempler F, Patsch W, Human peroxisome proliferator activated receptor gamma coactivator 1 (PPARGC1) gene: cDNA sequence, genomic organization, chromosomal localization, and tissue expression. Genomics. 1999 Nov 15;62(1):98-102
3*	J:91257 Gray PA, Fu H, Luo P, Zhao Q, Yu J, Ferrari A, Tenzen T, Yuk DI, Tsung EF, Cai Z, Alberta JA, Cheng LP, Liu Y, Stenman JM, Valerius MT, Billings N, Kim HA, Greenberg ME, McMahon AP, Rowitch DH, Stiles CD, Ma Q, Mouse Brain Organization Revealed Through Direct Genome-Scale TF Expression Analysis. Science. 2004 Dec 24;306(5705):2255-2257
2*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:314579 Higashiguchi Y, Katsuta K, Minegishi T, Yonemura S, Urasaki A, Inagaki N, Identification of a shootin1 isoform expressed in peripheral tissues. Cell Tissue Res. 2016 Oct;366(1):75-87
1*	J:58691 Hildebrand JD, Soriano P, Shroom, a PDZ domain-containing actin-binding protein, is required for neural tube morphogenesis in mice. Cell. 1999 Nov 24;99(5):485-97
1*	J:77905 Hildebrand JD, Soriano P, Overlapping and unique roles for C-terminal binding protein 1 (CtBP1) and CtBP2 during mouse development. Mol Cell Biol. 2002 Aug;22(15):5296-307
1	J:123924 Kim TH, Goodman J, Anderson KV, Niswander L, Phactr4 regulates neural tube and optic fissure closure by controlling PP1-, Rb-, and E2F1-regulated cell-cycle progression. Dev Cell. 2007 Jul;13(1):87-102
1*	J:228563 Koscielny G, Yaikhom G, Iyer V, Meehan TF, Morgan H, Atienza-Herrero J, Blake A, Chen CK, Easty R, Di Fenza A, Fiegel T, Grifiths M, Horne A, Karp NA, Kurbatova N, Mason JC, Matthews P, Oakley DJ, Qazi A, Regnart J, Retha A, Santos LA, Sneddon DJ, Warren J, Westerberg H, Wilson RJ, Melvin DG, Smedley D, Brown SD, Flicek P, Skarnes WC, Mallon AM, Parkinson H, The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9
1*	J:193822 Lumayag S, Haldin CE, Corbett NJ, Wahlin KJ, Cowan C, Turturro S, Larsen PE, Kovacs B, Witmer PD, Valle D, Zack DJ, Nicholson DA, Xu S, Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16
1*	J:280803 Ma J, Zhang LQ, He ZX, He XX, Wang YJ, Jian YL, Wang X, Zhang BB, Su C, Lu J, Huang BQ, Zhang Y, Wang GY, Guo WX, Qiu DL, Mei L, Xiong WC, Zheng YW, Zhu XJ, Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin. PLoS Biol. 2019 Oct;17(10):e3000461
1*	J:86589 McClive PJ, Hurley TM, Sarraj MA, van den Bergen JA, Sinclair AH, Subtractive hybridisation screen identifies sexually dimorphic gene expression in the embryonic mouse gonad. Genesis. 2003 Oct;37(2):84-90
1	J:292657 Pieters T, Sanders E, Tian H, van Hengel J, van Roy F, Neural defects caused by total and Wnt1-Cre mediated ablation of p120ctn in mice. BMC Dev Biol. 2020 Aug 3;20(1):17
1	J:148808 Sawallisch C, Berhorster K, Disanza A, Mantoani S, Kintscher M, Stoenica L, Dityatev A, Sieber S, Kindler S, Morellini F, Schweizer M, Boeckers TM, Korte M, Scita G, Kreienkamp HJ, The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity. J Biol Chem. 2009 Apr 3;284(14):9225-36
1	J:35786 Sparks AB, Hoffman NG, McConnell SJ, Fowlkes DM, Kay BK, Cloning of ligand targets: systematic isolation of SH3 domain-containing proteins. Nat Biotechnol. 1996 Jun;14(6):741-4
1	J:182258 Taher L, Collette NM, Murugesh D, Maxwell E, Ovcharenko I, Loots GG, Global gene expression analysis of murine limb development. PLoS One. 2011;6(12):e28358
1*	J:190636 Wiese CB, Ireland S, Fleming NL, Yu J, Valerius MT, Georgas K, Chiu HS, Brennan J, Armstrong J, Little MH, McMahon AP, Southard-Smith EM, A genome-wide screen to identify transcription factors expressed in pelvic ganglia of the lower urinary tract. Front Neurosci. 2012;6:130
1	J:311147 Yang Y, Wei M, Xiong Y, Du X, Zhu S, Yang L, Zhang C, Liu JJ, Endophilin A1 regulates dendritic spine morphogenesis and stability through interaction with p140Cap. Cell Res. 2015 Apr;25(4):496-516
3*	J:158029 Yu D, Zhang H, Blanpied TA, Smith E, Zhan X, Cortactin is implicated in murine zygotic development. Exp Cell Res. 2010 Mar 10;316(5):848-58
1	J:236302 Zhang X, Chen MH, Wu X, Kodani A, Fan J, Doan R, Ozawa M, Ma J, Yoshida N, Reiter JF, Black DL, Kharchenko PV, Sharp PA, Walsh CA, Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex. Cell. 2016 Aug 25;166(5):1147-1162.e15