Symbol Name ID |
Cdc25b
cell division cycle 25B MGI:99701 |
Age | E0.5 | E8.5 | E9 | E9.5 | E10.5 | E11 | E11.5 | E12 | E13 | E13.5 | E14 | E14.5 | E15 | E15.5 | E16 | E16.5 | E17 | E17.5 | E18 | E19 | E | P |
Immunohistochemistry (section) | 1 | |||||||||||||||||||||
In situ RNA (section) | 1 | 1 | 1 | 2 | 1 | 2 | 1 | 1 | 2 | 1 | 3 | 1 | 1 | 1 | 1 | 1 | 3 | |||||
Immunohistochemistry (whole mount) | 1 | 1 | ||||||||||||||||||||
In situ RNA (whole mount) | 1 | 1 | 1 | 1 | 1 | |||||||||||||||||
Northern blot | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 | ||||||||||||
Western blot | 1 | 1 | 1 | 4 | ||||||||||||||||||
RT-PCR | 1 | 2 | 3 | 1 | 7 | |||||||||||||||||
cDNA clones | 1 |
Cdc25b cell division cycle 25B | |
Results | Reference |
1* | J:327815 Beauchamp MC, Boucher A, Dong Y, Aber R, Jerome-Majewska LA, Craniofacial Defects in Embryos with Homozygous Deletion of Eftud2 in Their Neural Crest Cells Are Not Rescued by Trp53 Deletion. Int J Mol Sci. 2022 Aug 12;23(16) |
1* | J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034 |
7 | J:109315 Benazeraf B, Chen Q, Peco E, Lobjois V, Medevielle F, Ducommun B, Pituello F, Identification of an unexpected link between the Shh pathway and a G2/M regulator, the phosphatase CDC25B. Dev Biol. 2006 Jun 1;294(1):133-47 |
1 | J:279187 Bolte C, Ren X, Tomley T, Ustiyan V, Pradhan A, Hoggatt A, Kalin TV, Herring BP, Kalinichenko VV, Forkhead box F2 regulation of platelet-derived growth factor and myocardin/serum response factor signaling is essential for intestinal development. J Biol Chem. 2015 Mar 20;290(12):7563-75 |
1 | J:175788 Bolte C, Zhang Y, Wang IC, Kalin TV, Molkentin JD, Kalinichenko VV, Expression of Foxm1 transcription factor in cardiomyocytes is required for myocardial development. PLoS One. 2011;6(7):e22217 |
1 | J:310384 Bonnet F, Molina A, Roussat M, Azais M, Bel-Vialar S, Gautrais J, Pituello F, Agius E, Neurogenic decisions require a cell cycle independent function of the CDC25B phosphatase. Elife. 2018 Jul 3;7:e32937 |
1 | J:119653 Castro DS, Skowronska-Krawczyk D, Armant O, Donaldson IJ, Parras C, Hunt C, Critchley JA, Nguyen L, Gossler A, Gottgens B, Matter JM, Guillemot F, Proneural bHLH and Brn proteins coregulate a neurogenic program through cooperative binding to a conserved DNA motif. Dev Cell. 2006 Dec;11(6):831-44 |
1 | J:231798 Chen CY, Chan CH, Chen CM, Tsai YS, Tsai TY, Wu Lee YH, You LR, Targeted inactivation of murine Ddx3x: essential roles of Ddx3x in placentation and embryogenesis. Hum Mol Genet. 2016 July 15;25(14):2905-2922 |
1 | J:139978 Dakubo GD, Beug ST, Mazerolle CJ, Thurig S, Wang Y, Wallace VA, Control of glial precursor cell development in the mouse optic nerve by sonic hedgehog from retinal ganglion cells. Brain Res. 2008 Sep 4;1228:27-42 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
5 | J:355487 Han Z, Wang R, Chi P, Zhang Z, Min L, Jiao H, Ou G, Zhou D, Qin D, Xu C, Gao Z, Qi Q, Li J, Lu Y, Wang X, Chen J, Yu X, Hu H, Li L, Deng D, The subcortical maternal complex modulates the cell cycle during early mammalian embryogenesis via 14-3-3. Nat Commun. 2024 Oct 15;15(1):8887 |
16 | J:493 Kakizuka A, Sebastian B, Borgmeyer U, Hermans-Borgmeyer I, Bolado J, Hunter T, Hoekstra MF, Evans RM, A mouse cdc25 homolog is differentially and developmentally expressed. Genes Dev. 1992 Apr;6(4):578-90 |
1 | J:94883 Krupczak-Hollis K, Wang X, Kalinichenko VV, Gusarova GA, Wang IC, Dennewitz MB, Yoder HM, Kiyokawa H, Kaestner KH, Costa RH, The mouse Forkhead Box m1 transcription factor is essential for hepatoblast mitosis and development of intrahepatic bile ducts and vessels during liver morphogenesis. Dev Biol. 2004 Dec 1;276(1):74-88 |
1 | J:333724 Park EJ, Kim HS, Lee DH, Kim SM, Yoon JS, Lee JM, Im SJ, Lee H, Lee MW, Lee CW, Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation. Nat Commun. 2023 Feb 25;14(1):1097 |
1 | J:119481 Ramakrishna S, Kim IM, Petrovic V, Malin D, Wang IC, Kalin TV, Meliton L, Zhao YY, Ackerson T, Qin Y, Malik AB, Costa RH, Kalinichenko VV, Myocardium defects and ventricular hypoplasia in mice homozygous null for the Forkhead Box m1 transcription factor. Dev Dyn. 2007 Mar 15;236(4):1000-1013 |
4 | J:353313 Roussat M, Jungas T, Audouard C, Omerani S, Medevielle F, Agius E, Davy A, Pituello F, Bel-Vialar S, Control of G(2) Phase Duration by CDC25B Modulates the Switch from Direct to Indirect Neurogenesis in the Neocortex. J Neurosci. 2023 Feb 15;43(7):1154-1165 |
2* | J:81991 Schmidt EE, Bondareva AA, Radke JR, Capecchi MR, Fundamental cellular processes do not require vertebrate-specific sequences within the TATA-binding protein. J Biol Chem. 2003 Feb 21;278(8):6168-74 |
2 | J:181834 Su YQ, Sugiura K, Sun F, Pendola JK, Cox GA, Handel MA, Schimenti JC, Eppig JJ, MARF1 regulates essential oogenic processes in mice. Science. 2012 Mar 23;335(6075):1496-9 |
1* | J:272586 Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, Yamamoto T, Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019 Feb 15;146(4):dev168146 |
1 | J:315979 Tane S, Kubota M, Okayama H, Ikenishi A, Yoshitome S, Iwamoto N, Satoh Y, Kusakabe A, Ogawa S, Kanai A, Molkentin JD, Nakamura K, Ohbayashi T, Takeuchi T, Repression of cyclin D1 expression is necessary for the maintenance of cell cycle exit in adult mammalian cardiomyocytes. J Biol Chem. 2014 Jun 27;289(26):18033-44 |
1 | J:228807 Umansky KB, Gruenbaum-Cohen Y, Tsoory M, Feldmesser E, Goldenberg D, Brenner O, Groner Y, Runx1 Transcription Factor Is Required for Myoblasts Proliferation during Muscle Regeneration. PLoS Genet. 2015 Aug;11(8):e1005457 |
1 | J:221298 Wang Y, Hu G, Liu F, Wang X, Wu M, Schwarz JJ, Zhou J, Deletion of yes-associated protein (YAP) specifically in cardiac and vascular smooth muscle cells reveals a crucial role for YAP in mouse cardiovascular development. Circ Res. 2014 Mar 14;114(6):957-65 |
5* | J:26754 Wickramasinghe D, Becker S, Ernst MK, Resnick JL, Centanni JM, Tessarollo L, Grabel LB, Donovan PJ, Two CDC25 homologues are differentially expressed during mouse development. Development. 1995 Jul;121(7):2047-56 |
2* | J:26789 Wu S, Wolgemuth DJ, The distinct and developmentally regulated patterns of expression of members of the mouse Cdc25 gene family suggest differential functions during gametogenesis. Dev Biol. 1995 Jul;170(1):195-206 |
2 | J:206964 Wu X, Gu X, Han X, Du A, Jiang Y, Zhang X, Wang Y, Cao G, Zhao C, A novel function for Foxm1 in interkinetic nuclear migration in the developing telencephalon and anxiety-related behavior. J Neurosci. 2014 Jan 22;34(4):1510-22 |
1 | J:208115 Zander MA, Burns SE, Yang G, Kaplan DR, Miller FD, Snail coordinately regulates downstream pathways to control multiple aspects of Mammalian neural precursor development. J Neurosci. 2014 Apr 9;34(15):5164-75 |
1* | J:330334 Zhang H, Jiang JC, Wu YW, Yu YS, Wang HN, Ding NZ, Fan HY, The RNA ligase RNA terminal phosphate cyclase B regulates mRNA alternative splicing and is required for mouse oocyte development and maintenance. Development. 2022 Oct 1;149(19):dev200497 |
1 | J:261328 Zou J, Ma W, Li J, Littlejohn R, Zhou H, Kim IM, Fulton DJR, Chen W, Weintraub NL, Zhou J, Su H, Neddylation mediates ventricular chamber maturation through repression of Hippo signaling. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4101-E4110 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 11/12/2024 MGI 6.24 |
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