Gene Expression Literature Summary

• Symbol: Tgfbi
• Name: transforming growth factor, beta induced
• ID: MGI:99959

41 matching records from 41 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E7.5	E8.5	E9	E9.5	E10	E10.5	E11	E11.5	E12	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17	E17.5	E18	E18.5	E19	P
Immunohistochemistry (section)															1					1		1		2
In situ RNA (section)		1		2	1	3		2		6		4	1	7	2	8	1	4	1	3	1	4		6
In situ RNA (whole mount)		1	1	3		2		1		2		2
In situ reporter (knock in)									1						1				1					1
Northern blot												1								1				1
Western blot																								2
RT-PCR	1			1		1	1				1	3		1	2			1	1		1	3	1	6
cDNA clones																								1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tgfbi  transforming growth factor, beta induced   (Synonyms: 68kDa, Beta-ig, bIG-h3)
Results	Reference
1	J:246645 Adikusuma F, Pederick D, McAninch D, Hughes J, Thomas P, Functional Equivalence of the SOX2 and SOX3 Transcription Factors in the Developing Mouse Brain and Testes. Genetics. 2017 Jul;206(3):1495-1503
11	J:231522 Ahlfeld SK, Wang J, Gao Y, Snider P, Conway SJ, Initial Suppression of Transforming Growth Factor-beta Signaling and Loss of TGFBI Causes Early Alveolar Structural Defects Resulting in Bronchopulmonary Dysplasia. Am J Pathol. 2016 Apr;186(4):777-93
1*	J:313619 Bedogni F, Hevner RF, Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Front Mol Neurosci. 2021;14:686034
4	J:236397 Bildsoe H, Fan X, Wilkie EE, Ashoti A, Jones VJ, Power M, Qin J, Wang J, Tam PP, Loebel DA, Transcriptional targets of TWIST1 in the cranial mesoderm regulate cell-matrix interactions and mesenchyme maintenance. Dev Biol. 2016 Oct 1;418(1):189-203
5	J:214677 Bohnenpoll T, Trowe MO, Wojahn I, Taketo MM, Petry M, Kispert A, Canonical Wnt signaling regulates the proliferative expansion and differentiation of fibrocytes in the murine inner ear. Dev Biol. 2014 Jul 1;391(1):54-65
3*	J:155785 Brinkmeier ML, Davis SW, Carninci P, MacDonald JW, Kawai J, Ghosh D, Hayashizaki Y, Lyons RH, Camper SA, Discovery of transcriptional regulators and signaling pathways in the developing pituitary gland by bioinformatic and genomic approaches. Genomics. 2009 May;93(5):449-60
2	J:124144 Chen F, Desai TJ, Qian J, Niederreither K, Lu J, Cardoso WV, Inhibition of Tgf{beta} signaling by endogenous retinoic acid is essential for primary lung bud induction. Development. 2007 Aug;134(16):2969-79
1	J:161416 Collette NM, Genetos DC, Murugesh D, Harland RM, Loots GG, Genetic evidence that SOST inhibits WNT signaling in the limb. Dev Biol. 2010 Jun 15;342(2):169-79
1*	J:148410 Combes AN, Lesieur E, Harley VR, Sinclair AH, Little MH, Wilhelm D, Koopman P, Three-dimensional visualization of testis cord morphogenesis, a novel tubulogenic mechanism in development. Dev Dyn. 2009 May;238(5):1033-41
1*	J:291486 Daniel E, Barlow HR, Sutton GI, Gu X, Htike Y, Cowdin MA, Cleaver O, Cyp26b1 is an essential regulator of distal airway epithelial differentiation during lung development. Development. 2020 Feb 20;147(4):dev181560
1	J:108241 Desai J, Shannon ME, Johnson MD, Ruff DW, Hughes LA, Kerley MK, Carpenter DA, Johnson DK, Rinchik EM, Culiat CT, Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects. Hum Mol Genet. 2006 Apr 15;15(8):1329-41
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
7*	J:85509 Ferguson JW, Mikesh MF, Wheeler EF, LeBaron RG, Developmental expression patterns of Beta-ig (betaIG-H3) and its function as a cell adhesion protein. Mech Dev. 2003 Aug;120(8):851-64
6	J:84735 Ferguson JW, Thoma BS, Mikesh MF, Kramer RH, Bennett KL, Purchio A, Bellard BJ, LeBaron RG, The extracellular matrix protein betaIG-H3 is expressed at myotendinous junctions and supports muscle cell adhesion. Cell Tissue Res. 2003 Jul;313(1):93-105
5*	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1	J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87
1	J:283418 Hill MC, Kadow ZA, Li L, Tran TT, Wythe JD, Martin JF, A cellular atlas of Pitx2-dependent cardiac development. Development. 2019 Jun 14;146(12):dev180398
1*	J:234970 Kalyani R, Lee JY, Min H, Yoon H, Kim MH, Genes Frequently Coexpressed with Hoxc8 Provide Insight into the Discovery of Target Genes. Mol Cells. 2016 May 31;39(5):395-402
1	J:267504 Kiyama T, Chen CK, Wang SW, Pan P, Ju Z, Wang J, Takada S, Klein WH, Mao CA, Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis. Mol Neurodegener. 2018 Oct 17;13(1):56
1	J:184521 Koss M, Bolze A, Brendolan A, Saggese M, Capellini TD, Bojilova E, Boisson B, Prall OW, Elliott DA, Solloway M, Lenti E, Hidaka C, Chang CP, Mahlaoui N, Harvey RP, Casanova JL, Selleri L, Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module. Dev Cell. 2012 May 15;22(5):913-26
5	J:95310 Lepourcelet M, Tou L, Cai L, Sawada J, Lazar AJ, Glickman JN, Williamson JA, Everett AD, Redston M, Fox EA, Nakatani Y, Shivdasani RA, Insights into developmental mechanisms and cancers in the mammalian intestine derived from serial analysis of gene expression and study of the hepatoma-derived growth factor (HDGF). Development. 2005 Jan;132(2):415-27
2	J:302372 Li C, Smith SM, Peinado N, Gao F, Li W, Lee MK, Zhou B, Bellusci S, Pryhuber GS, Ho HH, Borok Z, Minoo P, WNT5a-ROR Signaling Is Essential for Alveologenesis. Cells. 2020 Feb 7;9(2):384
1	J:177567 Li D, Liu Y, Maruyama M, Zhu W, Chen H, Zhang W, Reuter S, Lin SF, Haneline LS, Field LJ, Chen PS, Shou W, Restrictive loss of plakoglobin in cardiomyocytes leads to arrhythmogenic cardiomyopathy. Hum Mol Genet. 2011 Dec 1;20(23):4582-96
9*	J:98689 Lindsley A, Li W, Wang J, Maeda N, Rogers R, Conway SJ, Comparison of the four mouse fasciclin-containing genes expression patterns during valvuloseptal morphogenesis. Gene Expr Patterns. 2005 Jun;5(5):593-600
3*	J:93154 Lu J, Qian J, Izvolsky KI, Cardoso WV, Global analysis of genes differentially expressed in branching and non-branching regions of the mouse embryonic lung. Dev Biol. 2004 Sep 15;273(2):418-35
3*	J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
1	J:213950 Mahoney JE, Mori M, Szymaniak AD, Varelas X, Cardoso WV, The hippo pathway effector Yap controls patterning and differentiation of airway epithelial progenitors. Dev Cell. 2014 Jul 28;30(2):137-50
1	J:187360 McKean DM, Niswander L, Defects in GPI biosynthesis perturb Cripto signaling during forebrain development in two new mouse models of holoprosencephaly. Biol Open. 2012;1(9):874-883
3*	J:316879 Negretti NM, Plosa EJ, Benjamin JT, Schuler BA, Habermann AC, Jetter CS, Gulleman P, Bunn C, Hackett AN, Ransom M, Taylor CJ, Nichols D, Matlock BK, Guttentag SH, Blackwell TS, Banovich NE, Kropski JA, Sucre JMS, A single-cell atlas of mouse lung development. Development. 2021 Dec 15;148(24):dev199512
1	J:143444 Park EJ, Watanabe Y, Smyth G, Miyagawa-Tomita S, Meyers E, Klingensmith J, Camenisch T, Buckingham M, Moon AM, An FGF autocrine loop initiated in second heart field mesoderm regulates morphogenesis at the arterial pole of the heart. Development. 2008 Nov;135(21):3599-610
2*	J:187969 Pazin DE, Gamer LW, Cox KA, Rosen V, Molecular profiling of synovial joints: Use of microarray analysis to identify factors that direct the development of the knee and elbow. Dev Dyn. 2012 Nov;241(11):1816-26
3	J:333399 Rhee S, Paik DT, Yang JY, Nagelberg D, Williams I, Tian L, Roth R, Chandy M, Ban J, Belbachir N, Kim S, Zhang H, Phansalkar R, Wong KM, King DA, Valdez C, Winn VD, Morrison AJ, Wu JC, Red-Horse K, Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction. Eur Heart J. 2021 Nov 1;42(41):4264-4276
8*	J:63731 Schorderet DF, Menasche M, Morand S, Bonnel S, Buchillier V, Marchant D, Auderset K, Bonny C, Abitbol M, Munier FL, Genomic characterization and embryonic expression of the mouse Bigh3 (Tgfbi) gene. Biochem Biophys Res Commun. 2000 Aug 2;274(2):267-74
2	J:86350 Schwab K, Patterson LT, Aronow BJ, Luckas R, Liang HC, Potter SS, A catalogue of gene expression in the developing kidney. Kidney Int. 2003 Nov;64(5):1588-604
1*	J:216843 Shelton EL, Ector G, Galindo CL, Hooper CW, Brown N, Wilkerson I, Pfaltzgraff ER, Paria BC, Cotton RB, Stoller JZ, Reese J, Transcriptional profiling reveals ductus arteriosus-specific genes that regulate vascular tone. Physiol Genomics. 2014 Jul 1;46(13):457-66
2	J:147647 Snider P, Hinton RB, Moreno-Rodriguez RA, Wang J, Rogers R, Lindsley A, Li F, Ingram DA, Menick D, Field L, Firulli AB, Molkentin JD, Markwald R, Conway SJ, Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart. Circ Res. 2008 Apr 11;102(7):752-60
1	J:171050 Thiagarajan RD, Georgas KM, Rumballe BA, Lesieur E, Chiu HS, Taylor D, Tang DT, Grimmond SM, Little MH, Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. PLoS One. 2011;6(2):e17286
1	J:182757 Wilson DG, Phamluong K, Lin WY, Barck K, Carano RA, Diehl L, Peterson AS, Martin F, Solloway MJ, Chondroitin sulfate synthase 1 (Chsy1) is required for bone development and digit patterning. Dev Biol. 2012 Mar 15;363(2):413-25
1*	J:341382 Wu B, Wu B, Benkaci S, Shi L, Lu P, Park T, Morrow BE, Wang Y, Zhou B, Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development. J Am Heart Assoc. 2023 Sep 19;12(18):e029683
2	J:344566 Zanini F, Che X, Suresh NE, Knutsen C, Klavina P, Xie Y, Domingo-Gonzalez R, Liu M, Kum A, Jones RC, Quake SR, Alvira CM, Cornfield DN, Hyperoxia prevents the dynamic neonatal increases in lung mesenchymal cell diversity. Sci Rep. 2024 Jan 23;14(1):2033
1*	J:356741 Zhang S, Mo X, Jin Y, Niu Z, Yao M, Zhang Y, Li L, Hu G, Ning W, Single-cell transcriptome analysis reveals cellular heterogeneity and highlights Fstl1-regulated alveolar myofibroblasts in mouse lung at birth. Genomics. 2023 Sep;115(5):110677