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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
11.5 DPC

24 matching records from 24 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Tbx2  T-box 2  
Results  Reference
1J:283343 Bastida MF, Perez-Gomez R, Trofka A, Zhu J, Rada-Iglesias A, Sheth R, Stadler HS, Mackem S, Ros MA, The formation of the thumb requires direct modulation of Gli3 transcription by Hoxa13. Proc Natl Acad Sci U S A. 2020 Jan 14;117(2):1090-1096
1J:120113 Behesti H, Holt JK, Sowden JC, The level of BMP4 signaling is critical for the regulation of distinct T-box gene expression domains and growth along the dorso-ventral axis of the optic cup. BMC Dev Biol. 2006;6:62
1*J:152494 Behesti H, Papaioannou VE, Sowden JC, Loss of Tbx2 delays optic vesicle invagination leading to small optic cups. Dev Biol. 2009 Sep 15;333(2):360-72
1*J:34541 Chapman DL, Garvey N, Hancock S, Alexiou M, Agulnik SI, Gibson-Brown JJ, Cebra-Thomas J, Bollag RJ, Silver LM, Papaioannou VE, Expression of the T-box family genes, Tbx1-Tbx5, during early mouse development. Dev Dyn. 1996 Aug;206(4):379-90
1*J:82458 Davenport TG, Jerome-Majewska LA, Papaioannou VE, Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome. Development. 2003 May;130(10):2263-73
1J:113522 Deng J, Dekruyff RH, Freeman GJ, Umetsu DT, Levy S, Critical role of CD81 in cognate T-B cell interactions leading to Th2 responses. Int Immunol. 2002 May;14(5):513-23
1*J:179731 Douglas NC, Heng K, Sauer MV, Papaioannou VE, Dynamic expression of Tbx2 subfamily genes in development of the mouse reproductive system. Dev Dyn. 2012 Feb;241(2):365-75
1J:200023 Farin HF, Ludtke TH, Schmidt MK, Placzko S, Schuster-Gossler K, Petry M, Christoffels VM, Kispert A, Tbx2 terminates shh/fgf signaling in the developing mouse limb bud by direct repression of gremlin1. PLoS Genet. 2013;9(4):e1003467
1*J:33697 Gibson-Brown JJ, Agulnik SI, Chapman DL, Alexiou M, Garvey N, Silver LM, Papaioannou VE, Evidence of a role for T-box genes in the evolution of limb morphogenesis and the specification of forelimb/hindlimb identity. Mech Dev. 1996 May;56(1-2):93-101
1J:113422 Harrelson Z, Papaioannou VE, Segmental expression of the T-box transcription factor, Tbx2, during early somitogenesis. Dev Dyn. 2006 Nov;235(11):3080-4
1*J:149502 Hill P, Gotz K, Ruther U, A SHH-independent regulation of Gli3 is a significant determinant of anteroposterior patterning of the limb bud. Dev Biol. 2009 Apr 15;328(2):506-16
1J:125087 Hill P, Wang B, Ruther U, The molecular basis of Pallister Hall associated polydactyly. Hum Mol Genet. 2007 Sep 1;16(17):2089-96
1J:184018 Itou J, Kawakami H, Quach T, Osterwalder M, Evans SM, Zeller R, Kawakami Y, Islet1 regulates establishment of the posterior hindlimb field upstream of the Hand2-Shh morphoregulatory gene network in mouse embryos. Development. 2012 May;139(9):1620-9
1J:102855 Jerome-Majewska LA, Jenkins GP, Ernstoff E, Zindy F, Sherr CJ, Papaioannou VE, Tbx3, the ulnar-mammary syndrome gene, and Tbx2 interact in mammary gland development through a p19Arf/p53-independent pathway. Dev Dyn. 2005 Dec;234(4):922-33
1J:312493 Jhanwar S, Malkmus J, Stolte J, Romashkina O, Zuniga A, Zeller R, Conserved and species-specific chromatin remodeling and regulatory dynamics during mouse and chicken limb bud development. Nat Commun. 2021 Sep 28;12(1):5685
1*J:226028 Lewandowski JP, Du F, Zhang S, Powell MB, Falkenstein KN, Ji H, Vokes SA, Spatiotemporal regulation of GLI target genes in the mammalian limb bud. Dev Biol. 2015 Oct 1;406(1):92-103
1J:129204 Robertson EJ, Charatsi I, Joyner CJ, Koonce CH, Morgan M, Islam A, Paterson C, Lejsek E, Arnold SJ, Kallies A, Nutt SL, Bikoff EK, Blimp1 regulates development of the posterior forelimb, caudal pharyngeal arches, heart and sensory vibrissae in mice. Development. 2007 Dec;134(24):4335-45
1*J:209112 Shimizu H, Kubo A, Uchibe K, Hashimoto M, Yokoyama S, Takada S, Mitsuoka K, Asahara H, The AERO system: a 3D-like approach for recording gene expression patterns in the whole mouse embryo. PLoS One. 2013;8(10):e75754
1J:87949 Suzuki T, Takeuchi J, Koshiba-Takeuchi K, Ogura T, Tbx Genes Specify Posterior Digit Identity through Shh and BMP Signaling. Dev Cell. 2004 Jan;6(1):43-53
1J:185554 Wu CI, Hoffman JA, Shy BR, Ford EM, Fuchs E, Nguyen H, Merrill BJ, Function of Wnt/beta-catenin in counteracting Tcf3 repression through the Tcf3-beta-catenin interaction. Development. 2012 Jun;139(12):2118-29
1J:107396 Yang L, Cai CL, Lin L, Qyang Y, Chung C, Monteiro RM, Mummery CL, Fishman GI, Cogen A, Evans S, Isl1Cre reveals a common Bmp pathway in heart and limb development. Development. 2006 Apr;133(8):1575-85
1*J:156017 Yokoyama S, Ito Y, Ueno-Kudoh H, Shimizu H, Uchibe K, Albini S, Mitsuoka K, Miyaki S, Kiso M, Nagai A, Hikata T, Osada T, Fukuda N, Yamashita S, Harada D, Mezzano V, Kasai M, Puri PL, Hayashizaki Y, Okado H, Hashimoto M, Asahara H, A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Dev Cell. 2009 Dec;17(6):836-48
1J:135157 Zhu J, Nakamura E, Nguyen MT, Bao X, Akiyama H, Mackem S, Uncoupling Sonic hedgehog control of pattern and expansion of the developing limb bud. Dev Cell. 2008 Apr;14(4):624-32
1J:154920 Zirzow S, Ludtke TH, Brons JF, Petry M, Christoffels VM, Kispert A, Expression and requirement of T-box transcription factors Tbx2 and Tbx3 during secondary palate development in the mouse. Dev Biol. 2009 Dec 15;336(2):145-55
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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07/02/2024
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