Assay
Age
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In situ RNA (section)
12.5 DPC
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Cxcr4 C-X-C motif chemokine receptor 4 (Synonyms: b2b220Clo, CD184, Cmkar4, fusin, PB-CKR, Sdf1r) | |
Results | Reference |
1 | J:226478 Abe P, Molnar Z, Tzeng YS, Lai DM, Arnold SJ, Stumm R, Intermediate Progenitors Facilitate Intracortical Progression of Thalamocortical Axons and Interneurons through CXCL12 Chemokine Signaling. J Neurosci. 2015 Sep 23;35(38):13053-63 |
1 | J:184876 Chiara F, Badaloni A, Croci L, Yeh ML, Cariboni A, Hoerder-Suabedissen A, Consalez GG, Eickholt B, Shimogori T, Parnavelas JG, Rakic S, Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem. Dev Biol. 2012 May 1;365(1):277-89 |
1 | J:333567 Gonzalez-Meljem JM, Ivins S, Andoniadou CL, Le Tissier P, Scambler P, Martinez-Barbera JP, An expression and function analysis of the CXCR4/SDF-1 signalling axis during pituitary gland development. PLoS One. 2023;18(2):e0280001 |
1 | J:189818 Haege S, Einer C, Thiele S, Mueller W, Nietzsche S, Lupp A, Mackay F, Schulz S, Stumm R, CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney. PLoS One. 2012;7(8):e42814 |
1* | J:156021 Hick AC, van Eyll JM, Cordi S, Forez C, Passante L, Kohara H, Nagasawa T, Vanderhaeghen P, Courtoy PJ, Rousseau GG, Lemaigre FP, Pierreux CE, Mechanism of primitive duct formation in the pancreas and submandibular glands: a role for SDF-1. BMC Dev Biol. 2009;9:66 |
1 | J:239364 Ivins S, Chappell J, Vernay B, Suntharalingham J, Martineau A, Mohun TJ, Scambler PJ, The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development. Dev Cell. 2015 May 26;33(4):455-68 |
1 | J:344967 Le VH, Orniacki C, Murcia-Belmonte V, Denti L, Schutz D, Stumm R, Ruhrberg C, Erskine L, CXCL12 promotes the crossing of retinal ganglion cell axons at the optic chiasm. Development. 2024 Jan 15;151(2) |
1 | J:167360 Li M, Chang CJ, Lathia JD, Wang L, Pacenta HL, Cotleur A, Ransohoff RM, Chemokine receptor CXCR4 signaling modulates the growth factor-induced cell cycle of self-renewing and multipotent neural progenitor cells. Glia. 2011 Jan;59(1):108-18 |
1 | J:101029 Lieberam I, Agalliu D, Nagasawa T, Ericson J, Jessell TM, A Cxcl12-CXCR4 chemokine signaling pathway defines the initial trajectory of mammalian motor axons. Neuron. 2005 Sep 1;47(5):667-79 |
1* | J:57676 McGrath KE, Koniski AD, Maltby KM, McGann JK, Palis J, Embryonic expression and function of the chemokine SDF-1 and its receptor, CXCR4. Dev Biol. 1999 Sep 15;213(2):442-56 |
1 | J:204198 Memi F, Abe P, Cariboni A, MacKay F, Parnavelas JG, Stumm R, CXC chemokine receptor 7 (CXCR7) affects the migration of GnRH neurons by regulating CXCL12 availability. J Neurosci. 2013 Oct 30;33(44):17527-37 |
1 | J:267985 Page M, Ridge L, Gold Diaz D, Tsogbayar T, Scambler PJ, Ivins S, Loss of CXCL12/CXCR4 signalling impacts several aspects of cardiovascular development but does not exacerbate Tbx1 haploinsufficiency. PLoS One. 2018;13(11):e0207251 |
1 | J:109982 Schwarting GA, Henion TR, Nugent JD, Caplan B, Tobet S, Stromal cell-derived factor-1 (chemokine C-X-C motif ligand 12) and chemokine C-X-C motif receptor 4 are required for migration of gonadotropin-releasing hormone neurons to the forebrain. J Neurosci. 2006 Jun 21;26(25):6834-40 |
1 | J:124878 Sierro F, Biben C, Martinez-Munoz L, Mellado M, Ransohoff RM, Li M, Woehl B, Leung H, Groom J, Batten M, Harvey RP, Martinez-A C, Mackay CR, Mackay F, Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14759-64 |
1 | J:88781 Tissir F, Wang CE, Goffinet AM, Expression of the chemokine receptor Cxcr4 mRNA during mouse brain development. Brain Res Dev Brain Res. 2004 Mar 22;149(1):63-71 |
1* | J:272319 Tiveron MC, Boutin C, Daou P, Moepps B, Cremer H, Expression and function of CXCR7 in the mouse forebrain. J Neuroimmunol. 2010;224(1-2):72-9 |
1 | J:204963 Yang S, Edman LC, Sanchez-Alcaniz JA, Fritz N, Bonilla S, Hecht J, Uhlen P, Pleasure SJ, Villaescusa JC, Marin O, Arenas E, Cxcl12/Cxcr4 signaling controls the migration and process orientation of A9-A10 dopaminergic neurons. Development. 2013 Nov;140(22):4554-64 |
1 | J:274885 Zhang H, Bagherie-Lachidan M, Badouel C, Enderle L, Peidis P, Bremner R, Kuure S, Jain S, McNeill H, FAT4 Fine-Tunes Kidney Development by Regulating RET Signaling. Dev Cell. 2019 Mar 25;48(6):780-792.e4 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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