Gene Expression Literature Summary

Assay

Age

In situ RNA (section)

14.5 DPC

23 matching records from 23 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tpbpa trophoblast specific protein alpha (Synonyms: 4311, clone 4311, Tb1, Tb-1, Tpbp)
Results	Reference
1	J:231798 Chen CY, Chan CH, Chen CM, Tsai YS, Tsai TY, Wu Lee YH, You LR, Targeted inactivation of murine Ddx3x: essential roles of Ddx3x in placentation and embryogenesis. Hum Mol Genet. 2016 July 15;25(14):2905-2922
1*	J:275147 Chou AM, Sem KP, Lam WJ, Ahmed S, Lim CY, Redundant functions of I-BAR family members, IRSp53 and IRTKS, are essential for embryonic development. Sci Rep. 2017 Jan 9;7:40485
1*	J:64703 Cocchia M, Huber R, Pantano S, Chen EY, Ma P, Forabosco A, Ko MS, Schlessinger D, PLAC1, an Xq26 gene with placenta-specific expression. Genomics. 2000 Sep 15;68(3):305-12
1	J:249801 Duval C, Dilworth MR, Tunster SJ, Kimber SJ, Glazier JD, PTHrP is essential for normal morphogenetic and functional development of the murine placenta. Dev Biol. 2017 Oct 15;430(2):325-336
1*	J:218174 Hasan MZ, Ikawati M, Tocharus J, Kawaichi M, Oka C, Abnormal development of placenta in HtrA1-deficient mice. Dev Biol. 2015 Jan 1;397(1):89-102
1	J:50590 Li Y, Behringer RR, Esx1 is an X-chromosome-imprinted regulator of placental development and fetal growth. Nat Genet. 1998 Nov;20(3):309-11
1*	J:36835 Monkley SJ, Delaney SJ, Pennisi DJ, Christiansen JH, Wainwright BJ, Targeted disruption of the Wnt2 gene results in placentation defects. Development. 1996 Nov;122(11):3343-53
1	J:161410 Oh-McGinnis R, Bogutz AB, Lee KY, Higgins MJ, Lefebvre L, Rescue of placental phenotype in a mechanistic model of Beckwith-Wiedemann syndrome. BMC Dev Biol. 2010;10:50
1	J:261316 Perez-Garcia V, Fineberg E, Wilson R, Murray A, Mazzeo CI, Tudor C, Sienerth A, White JK, Tuck E, Ryder EJ, Gleeson D, Siragher E, Wardle-Jones H, Staudt N, Wali N, Collins J, Geyer S, Busch-Nentwich EM, Galli A, Smith JC, Robertson E, Adams DJ, Weninger WJ, Mohun T, Hemberger M, Placentation defects are highly prevalent in embryonic lethal mouse mutants. Nature. 2018 Mar 22;555(7697):463-468
1	J:333799 Radford BN, Zhao X, Glazer T, Eaton M, Blackwell D, Mohammad S, Lo Vercio LD, Devine J, Shalom-Barak T, Hallgrimsson B, Cross JC, Sucov HM, Barak Y, Dean W, Hemberger M, Defects in placental syncytiotrophoblast cells are a common cause of developmental heart disease. Nat Commun. 2023 Mar 1;14(1):1174
1*	J:258221 Rakoczy J, Padmanabhan N, Krzak AM, Kieckbusch J, Cindrova-Davies T, Watson ED, Dynamic expression of TET1, TET2, and TET3 dioxygenases in mouse and human placentas throughout gestation. Placenta. 2017 Nov;59:46-56
1	J:239786 Rakoczy J, Zhang Z, Bowling FG, Dawson PA, Simmons DG, Loss of the sulfate transporter Slc13a4 in placenta causes severe fetal abnormalities and death in mice. Cell Res. 2015 Nov;25(11):1273-6
1	J:87595 Rodriguez TA, Sparrow DB, Scott AN, Withington SL, Preis JI, Michalicek J, Clements M, Tsang TE, Shioda T, Beddington RS, Dunwoodie SL, Cited1 is required in trophoblasts for placental development and for embryo growth and survival. Mol Cell Biol. 2004 Jan;24(1):228-44
1	J:44230 Sapin V, Dolle P, Hindelang C, Kastner P, Chambon P, Defects of the chorioallantoic placenta in mouse RXRalpha null fetuses. Dev Biol. 1997 Nov 1;191(1):29-41
1	J:240089 Sharma N, Kubaczka C, Kaiser S, Nettersheim D, Mughal SS, Riesenberg S, Holzel M, Winterhager E, Schorle H, Tpbpa-Cre-mediated deletion of TFAP2C leads to deregulation of Cdkn1a, Akt1 and the ERK pathway, causing placental growth arrest. Development. 2016 Mar 01;143(5):787-98
1	J:228795 Tunster SJ, Creeth HD, John RM, The imprinted Phlda2 gene modulates a major endocrine compartment of the placenta to regulate placental demands for maternal resources. Dev Biol. 2016 Jan 1;409(1):251-60
1	J:236398 Tunster SJ, McNamara GI, Creeth HD, John RM, Increased dosage of the imprinted Ascl2 gene restrains two key endocrine lineages of the mouse Placenta. Dev Biol. 2016 Oct 1;418(1):55-65
1	J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306
1	J:267708 Tunster SJ, Van de Pette M, Creeth HDJ, Lefebvre L, John RM, Fetal growth restriction in a genetic model of sporadic Beckwith-Wiedemann syndrome. Dis Model Mech. 2018 Nov 16;11(11):dmm035832
1	J:290416 Vrooman LA, Rhon-Calderon EA, Chao OY, Nguyen DK, Narapareddy L, Dahiya AK, Putt ME, Schultz RM, Bartolomei MS, Assisted reproductive technologies induce temporally specific placental defects and the preeclampsia risk marker sFLT1 in mouse. Development. 2020 May 29;147(11):dev186551
1	J:63500 Wessells J, Wessner D, Parsells R, White K, Finkenzeller D, Zimmermann W, Dveksler G, Pregnancy specific glycoprotein 18 induces IL-10 expression in murine macrophages. Eur J Immunol. 2000 Jul;30(7):1830-40
1*	J:109335 Withington SL, Scott AN, Saunders DN, Lopes Floro K, Preis JI, Michalicek J, Maclean K, Sparrow DB, Barbera JP, Dunwoodie SL, Loss of Cited2 affects trophoblast formation and vascularization of the mouse placenta. Dev Biol. 2006 Jun 1;294(1):67-82
1	J:346630 Zhang X, He H, Yu H, Teng X, Wang Z, Li C, Li J, Yang H, Shen J, Wu T, Zhang F, Zhang Y, Wu Q, Maternal RNA transcription in Dlk1-Dio3 domain is critical for proper development of the mouse placental vasculature. Commun Biol. 2024 Mar 23;7(1):363

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