Assay
Age
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ANY
16.5 DPC
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0610005C13Rik RIKEN cDNA 0610005C13 gene | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
1500026H17Rik RIKEN cDNA 1500026H17 gene (Synonyms: VINAS) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
1600012P17Rik RIKEN cDNA 1600012P17 gene | |
Results | Reference |
3* | J:327983 Wang J, Noguchi S, Takizawa T, Negishi Y, Morita R, Luo SS, Takizawa T, Placenta-specific lncRNA 1600012P17Rik is expressed in spongiotrophoblast and glycogen trophoblast cells of mouse placenta. Histochem Cell Biol. 2022 Jul;158(1):65-78 |
1700012B09Rik RIKEN cDNA 1700012B09 gene (Synonyms: 1700007P19Rik) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
1700024G13Rik RIKEN cDNA 1700024G13 gene | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
1700028K03Rik RIKEN cDNA 1700028K03 gene (Synonyms: SCRE, Spo16) | |
Results | Reference |
1* | J:297328 Zhang Q, Ji SY, Busayavalasa K, Yu C, SPO16 binds SHOC1 to promote homologous recombination and crossing-over in meiotic prophase I. Sci Adv. 2019 Jan;5(1):eaau9780 |
1700042O10Rik RIKEN cDNA 1700042O10 gene | |
Results | Reference |
1* | J:308675 Prickett AR, Montibus B, Barkas N, Amante SM, Franco MM, Cowley M, Puszyk W, Shannon MF, Irving MD, Madon-Simon M, Ward A, Schulz R, Baldwin HS, Oakey RJ, Imprinted Gene Expression and Function of the Dopa Decarboxylase Gene in the Developing Heart. Front Cell Dev Biol. 2021;9:676543 |
1810009A15Rik RIKEN cDNA 1810009A15 gene | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1810015C11Rik RIKEN cDNA 1810015C11 gene | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1810034E14Rik RIKEN cDNA 1810034E14 gene | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
1810041H14Rik RIKEN cDNA 1810041H14 gene | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
1810065E05Rik RIKEN cDNA 1810065E05 gene | |
Results | Reference |
1 | J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90 |
2010001A14Rik RIKEN cDNA 2010001A14 gene | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
2010110K18Rik RIKEN cDNA 2010110K18 gene | |
Results | Reference |
1* | J:330442 Garcia-Padilla C, Dominguez JN, Lodde V, Munk R, Abdelmohsen K, Gorospe M, Jimenez-Sabado V, Ginel A, Hove-Madsen L, Aranega AE, Franco D, Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation. FASEB J. 2022 Jan;36(1):e22051 |
2300002M23Rik RIKEN cDNA 2300002M23 gene (Synonyms: emprin) | |
Results | Reference |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
2310043M15Rik RIKEN cDNA 2310043M15 gene | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
2810030D12Rik RIKEN cDNA 2810030D12 gene | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
2810429I04Rik RIKEN cDNA 2810429I04 gene (Synonyms: 1700024F13Rik) | |
Results | Reference |
1* | J:268850 Wang J, Chen X, Shen D, Ge D, Chen J, Pei J, Li Y, Yue Z, Feng J, Chu M, Nie Y, A long noncoding RNA NR_045363 controls cardiomyocyte proliferation and cardiac repair. J Mol Cell Cardiol. 2018 Dec 13;127:105-114 |
3425401B19Rik RIKEN cDNA 3425401B19 gene (Synonyms: CEFIP) | |
Results | Reference |
1* | J:350467 Li Y, Ma K, Dong Z, Gao S, Zhang J, Huang S, Yang J, Fang G, Li Y, Li X, Welch C, Griffin EL, Ramaswamy P, Valivullah Z, Liu X, Dong J, Wang DW, Du J, Chung WK, Li Y, Frameshift variants in C10orf71 cause dilated cardiomyopathy in human, mouse, and organoid models. J Clin Invest. 2024 Jun 17;134(12) |
4732463B04Rik RIKEN cDNA 4732463B04 gene | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
4732465J04Rik RIKEN cDNA 4732465J04 gene | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
4921524J17Rik RIKEN cDNA 4921524J17 gene | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
4930447C04Rik RIKEN cDNA 4930447C04 gene (Synonyms: 4921504I02Rik, A930035O15Rik, Six6as, Six6os1) | |
Results | Reference |
1* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
4930449I24Rik RIKEN cDNA 4930449I24 gene | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
4930481A15Rik RIKEN cDNA 4930481A15 gene | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
4930503L19Rik RIKEN cDNA 4930503L19 gene (Synonyms: Las2) | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
4933425B07Rik RIKEN cDNA 4933425B07 gene (Synonyms: Rik) | |
Results | Reference |
1 | J:313930 Tan L, Yu M, Li Y, Xue S, Chen J, Zhai Y, Fang X, Liu J, Liu J, Wu X, Xu H, Shen Q, Overexpression of Long Non-coding RNA 4933425B07Rik Causes Urinary Malformations in Mice. Front Cell Dev Biol. 2021;9:594640 |
5430402P08Rik RIKEN cDNA 5430402P08 gene (Synonyms: lncMREF) | |
Results | Reference |
1 | J:330270 Lv W, Jiang W, Luo H, Tong Q, Niu X, Liu X, Miao Y, Wang J, Guo Y, Li J, Zhan X, Hou Y, Peng Y, Wang J, Zhao S, Xu Z, Zuo B, Long noncoding RNA lncMREF promotes myogenic differentiation and muscle regeneration by interacting with the Smarca5/p300 complex. Nucleic Acids Res. 2022 Oct 14;50(18):10733-10755 |
5730522E02Rik RIKEN cDNA 5730522E02 gene | |
Results | Reference |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
6430548M08Rik RIKEN cDNA 6430548M08 gene (Synonyms: mKIAA0513) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
9030622O22Rik RIKEN cDNA 9030622O22 gene (Synonyms: Alien, Falcor) | |
Results | Reference |
1* | J:283316 Garcia-Padilla C, Dominguez JN, Aranega AE, Franco D, Differential chamber-specific expression and regulation of long non-coding RNAs during cardiac development. Biochim Biophys Acta Gene Regul Mech. 2019 Oct;1862(10):194435 |
1* | J:212084 Herriges MJ, Swarr DT, Morley MP, Rathi KS, Peng T, Stewart KM, Morrisey EE, Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development. Genes Dev. 2014 Jun 15;28(12):1363-79 |
9530018H14Rik RIKEN cDNA 9530018H14 gene (Synonyms: LncRNA-HIT) | |
Results | Reference |
1* | J:302776 Carlson HL, Stadler HS, Development and functional characterization of a lncRNA-HIT conditional loss of function allele. Genesis. 2020 Mar;58(3-4):e23351 |
A130040M12Rik RIKEN cDNA A130040M12 gene (Synonyms: H3053C11, VL30) | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
A330033J07Rik RIKEN cDNA A330033J07 gene | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
A330076H08Rik RIKEN cDNA A330076H08 gene (Synonyms: Mirh1) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
A430046D13Rik Riken cDNA A430046D13 gene | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
A630031M23Rik Riken cDNA A630031M23 gene | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
A730017L22Rik RIKEN cDNA A730017L22 gene | |
Results | Reference |
1 | J:331893 Yang J, Zhang L, Li Y, Chen M, Identifying key m(6)A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses. Front Genet. 2022;13:974357 |
A930024E05Rik RIKEN cDNA A930024E05 gene (Synonyms: Kancr, LncKdm2b) | |
Results | Reference |
2* | J:297829 Li W, Shen W, Zhang B, Tian K, Li Y, Mu L, Luo Z, Zhong X, Wu X, Liu Y, Zhou Y, Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b. Protein Cell. 2020 Mar;11(3):161-186 |
Aacs acetoacetyl-CoA synthetase (Synonyms: 2210408B16Rik) | |
Results | Reference |
1* | J:190090 Hasegawa S, Kume H, Iinuma S, Yamasaki M, Takahashi N, Fukui T, Acetoacetyl-CoA synthetase is essential for normal neuronal development. Biochem Biophys Res Commun. 2012 Oct 19;427(2):398-403 |
Aard alanine and arginine rich domain containing protein | |
Results | Reference |
1* | J:120357 Svingen T, Beverdam A, Verma P, Wilhelm D, Koopman P, Aard is specifically up-regulated in Sertoli cells during mouse testis differentiation. Int J Dev Biol. 2007;51:255-258 |
Aars1 alanyl-tRNA synthetase 1 (Synonyms: Aars, MGC:37368) | |
Results | Reference |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Aass aminoadipate-semialdehyde synthase (Synonyms: Lorsdh, LOR/SDH) | |
Results | Reference |
2 | J:352880 Guo Y, Wu J, Wang M, Wang X, Jian Y, Yang C, Guo W, The Metabolite Saccharopine Impairs Neuronal Development by Inhibiting the Neurotrophic Function of Glucose-6-Phosphate Isomerase. J Neurosci. 2022 Mar 30;42(13):2631-2646 |
Aatk apoptosis-associated tyrosine kinase (Synonyms: AATYK1, mKIAA0641) | |
Results | Reference |
1* | J:309496 Jiang C, Yang W, Fan Z, Teng P, Mei R, Yang J, Yang A, Qiu M, Zhao X, AATYK is a Novel Regulator of Oligodendrocyte Differentiation and Myelination. Neurosci Bull. 2018 Jun;34(3):527-533 |
Abca1 ATP-binding cassette, sub-family A member 1 (Synonyms: ABC1) | |
Results | Reference |
1* | J:360522 Luciani MF, Chimini G, The ATP binding cassette transporter ABC1, is required for the engulfment of corpses generated by apoptotic cell death. EMBO J. 1996 Jan 15;15(2):226-35 |
Abca3 ATP-binding cassette, sub-family A member 3 (Synonyms: 1810036E22Rik, Abc3, ABC-C) | |
Results | Reference |
1 | J:202949 Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J, Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18042-51 |
1 | J:270164 Guo M, Du Y, Gokey JJ, Ray S, Bell SM, Adam M, Sudha P, Perl AK, Deshmukh H, Potter SS, Whitsett JA, Xu Y, Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth. Nat Commun. 2019 Jan 3;10(1):37 |
1 | J:264719 Moghieb A, Clair G, Mitchell HD, Kitzmiller J, Zink EM, Kim YM, Petyuk V, Shukla A, Moore RJ, Metz TO, Carson J, McDermott JE, Corley RA, Whitsett JA, Ansong C, Time-resolved proteome profiling of normal lung development. Am J Physiol Lung Cell Mol Physiol. 2018 Jul 1;315(1):L11-L24 |
2* | J:123083 Stahlman MT, Besnard V, Wert SE, Weaver TE, Dingle S, Xu Y, von Zychlin K, Olson SJ, Whitsett JA, Expression of ABCA3 in developing lung and other tissues. J Histochem Cytochem. 2007 Jan;55(1):71-83 |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
Abcb1a ATP-binding cassette, sub-family B member 1A (Synonyms: Evi32, Mdr1a, mdr-3, MDR3, multiple drug resistant 1a, P-glycoprotein, P-gp, Pgp, Pgy-3, Pgy3) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Abcb7 ATP-binding cassette, sub-family B member 7 (Synonyms: Abc7) | |
Results | Reference |
1* | J:39831 Savary S, Allikmets R, Denizot F, Luciani MF, Mattei MG, Dean M, Chimini G, Isolation and chromosomal mapping of a novel ATP-binding cassette transporter conserved in mouse and human. Genomics. 1997 Apr 15;41(2):275-8 |
Abcc6 ATP-binding cassette, sub-family C member 6 (Synonyms: DCC, Dyscalc1, Mrp6) | |
Results | Reference |
2* | J:101483 Beck K, Dang K, Boyd CD, The tissue distribution of murine Abcc6 (Mrp6) during embryogenesis indicates that the presence of Abcc6 in elastic tissues is not required for elastic fiber assembly. J Mol Histol. 2005 Mar;36(3):167-70 |
Abcc8 ATP-binding cassette, sub-family C member 8 (Synonyms: D930031B21Rik, Sur, SUR1) | |
Results | Reference |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
1 | J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461 |
Abcc9 ATP-binding cassette, sub-family C member 9 (Synonyms: Sur2, SUR2A, SUR2B) | |
Results | Reference |
1* | J:259125 Yang J, Hung LH, Licht T, Kostin S, Looso M, Khrameeva E, Bindereif A, Schneider A, Braun T, RBM24 is a major regulator of muscle-specific alternative splicing. Dev Cell. 2014 Oct 13;31(1):87-99 |
Abcg1 ATP binding cassette subfamily G member 1 (Synonyms: Abc8, White) | |
Results | Reference |
1* | J:35459 Savary S, Denizot F, Luciani M, Mattei M, Chimini G, Molecular cloning of a mammalian ABC transporter homologous to Drosophila white gene. Mamm Genome. 1996 Sep;7(9):673-6 |
Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) (Synonyms: 4930430M16Rik, Bcrp) | |
Results | Reference |
1* | J:170274 Li L, Kwon HJ, Harada H, Ohshima H, Cho SW, Jung HS, Expression patterns of ABCG2, Bmi-1, Oct-3/4, and Yap in the developing mouse incisor. Gene Expr Patterns. 2011 Mar-Apr;11(3-4):163-70 |
2* | J:87367 Martin CM, Meeson AP, Robertson SM, Hawke TJ, Richardson JA, Bates S, Goetsch SC, Gallardo TD, Garry DJ, Persistent expression of the ATP-binding cassette transporter, Abcg2, identifies cardiac SP cells in the developing and adult heart. Dev Biol. 2004 Jan 1;265(1):262-75 |
Abcg5 ATP binding cassette subfamily G member 5 (Synonyms: cmp, Sterolin-1, tac, trac) | |
Results | Reference |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
Abcg8 ATP binding cassette subfamily G member 8 (Synonyms: 1300003C16Rik, Sterolin-2) | |
Results | Reference |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
Abhd2 abhydrolase domain containing 2 (Synonyms: 2210009N18Rik, LABH2) | |
Results | Reference |
1* | J:96209 Miyata K, Oike Y, Hoshii T, Maekawa H, Ogawa H, Suda T, Araki K, Yamamura KI, Increase of smooth muscle cell migration and of intimal hyperplasia in mice lacking the alpha/beta hydrolase domain containing 2 gene. Biochem Biophys Res Commun. 2005 Apr 1;329(1):296-304 |
Abhd4 abhydrolase domain containing 4 (Synonyms: 1110035H23Rik) | |
Results | Reference |
3 | J:299736 Laszlo ZI, Lele Z, Zoldi M, Miczan V, Mogor F, Simon GM, Mackie K, Kacskovics I, Cravatt BF, Katona I, ABHD4-dependent developmental anoikis safeguards the embryonic brain. Nat Commun. 2020 Aug 31;11(1):4363 |
Abhd5 abhydrolase domain containing 5 (Synonyms: 1300003D03Rik, 2010002J10Rik, CGI-58, IECN5, NCIE2) | |
Results | Reference |
1* | J:240055 Grond S, Radner FP, Eichmann TO, Kolb D, Grabner GF, Wolinski H, Gruber R, Hofer P, Heier C, Schauer S, Rulicke T, Hoefler G, Schmuth M, Elias PM, Lass A, Zechner R, Haemmerle G, Skin Barrier Development Depends on CGI-58 Protein Expression during Late-Stage Keratinocyte Differentiation. J Invest Dermatol. 2017 Feb;137(2):403-413 |
Abhd6 abhydrolase domain containing 6 (Synonyms: 0610041D24Rik) | |
Results | Reference |
1 | J:227268 Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Bjorklund P, Mackie K, Di Marzo V, Hokfelt TG, Dobrzyn A, Harkany T, Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6185-94 |
Abi1 abl interactor 1 (Synonyms: E3B1, Ssh3bp1) | |
Results | Reference |
1 | J:320846 Aviles EC, Krol A, Henle SJ, Burroughs-Garcia J, Deans MR, Goodrich LV, Fat3 acts through independent cytoskeletal effectors to coordinate asymmetric cell behaviors during polarized circuit assembly. Cell Rep. 2022 Feb 1;38(5):110307 |
Abi2 abl interactor 2 (Synonyms: 8430425M24Rik) | |
Results | Reference |
1 | J:320846 Aviles EC, Krol A, Henle SJ, Burroughs-Garcia J, Deans MR, Goodrich LV, Fat3 acts through independent cytoskeletal effectors to coordinate asymmetric cell behaviors during polarized circuit assembly. Cell Rep. 2022 Feb 1;38(5):110307 |
1* | J:95254 Grove M, Demyanenko G, Echarri A, Zipfel PA, Quiroz ME, Rodriguiz RM, Playford M, Martensen SA, Robinson MR, Wetsel WC, Maness PF, Pendergast AM, ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory. Mol Cell Biol. 2004 Dec;24(24):10905-22 |
Abi3bp ABI family member 3 binding protein (Synonyms: 5033411B22Rik, D930038M13Rik, eratin, TARSH) | |
Results | Reference |
2* | J:147117 Cheng TW, Gong Q, Secreted TARSH regulates olfactory mitral cell dendritic complexity. Eur J Neurosci. 2009 Mar;29(6):1083-95 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Abtb1 ankyrin repeat and BTB domain containing 1 (Synonyms: BPOZ, EF1ABP, MGC:7237) | |
Results | Reference |
1* | J:99372 van der Zwaag B, Burbach JP, Scharfe C, Oefner PJ, Brunner HG, Padberg GW, van Bokhoven H, Identifying new candidate genes for hereditary facial paresis on chromosome 3q21-q22 by RNA in situ hybridization in mouse. Genomics. 2005 Jul;86(1):55-67 |
Abtb2 ankyrin repeat and BTB domain containing 2 (Synonyms: BPOZ-2) | |
Results | Reference |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Acadm acyl-Coenzyme A dehydrogenase, medium chain (Synonyms: MCAD) | |
Results | Reference |
1* | J:65091 Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP, Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest. 2000 Oct;106(7):847-56 |
Acan aggrecan (Synonyms: Agc1, b2b183Clo, Cspg1) | |
Results | Reference |
1 | J:284333 Arai HN, Sato F, Yamamoto T, Woltjen K, Kiyonari H, Yoshimoto Y, Shukunami C, Akiyama H, Kist R, Sehara-Fujisawa A, Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate. Cell Rep. 2019 Oct 15;29(3):603-616.e5 |
1 | J:67299 Arikawa-Hirasawa E, Watanabe H, Takami H, Hassell JR, Yamada Y, Perlecan is essential for cartilage and cephalic development. Nat Genet. 1999 Nov;23(3):354-8 |
1 | J:126342 Bok J, Brunet LJ, Howard O, Burton Q, Wu DK, Role of hindbrain in inner ear morphogenesis: Analysis of Noggin knockout mice. Dev Biol. 2007 Nov 1;311(1):69-78 |
2* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1 | J:306056 Doyle DZ, Lam MM, Qalieh A, Qalieh Y, Sorel A, Funk OH, Kwan KY, Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity. Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2100686118 |
1* | J:227060 Fujikawa K, Yokohama-Tamaki T, Morita T, Baba O, Qin C, Shibata S, An in situ hybridization study of perlecan, DMP1, and MEPE in developing condylar cartilage of the fetal mouse mandible and limb bud cartilage. Eur J Histochem. 2015;59(3):2553 |
1 | J:74145 Gori F, Schipani E, Demay MB, Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development. J Cell Biochem. 2001 Apr 2-27;82(1):46-57 |
1 | J:271382 Hirota Y, Kubo KI, Fujino T, Yamamoto TT, Nakajima K, ApoER2 Controls Not Only Neuronal Migration in the Intermediate Zone But Also Termination of Migration in the Developing Cerebral Cortex. Cereb Cortex. 2018 Jan 1;28(1):223-235 |
1* | J:132023 Hwang CH, Wu DK, Noggin heterozygous mice: an animal model for congenital conductive hearing loss in humans. Hum Mol Genet. 2008 Mar 15;17(6):844-53 |
1 | J:122204 Imai F, Hirai S, Akimoto K, Koyama H, Miyata T, Ogawa M, Noguchi S, Sasaoka T, Noda T, Ohno S, Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex. Development. 2006 May;133(9):1735-44 |
1 | J:155442 Kawaki H, Kubota S, Suzuki A, Lazar N, Yamada T, Matsumura T, Ohgawara T, Maeda T, Perbal B, Lyons KM, Takigawa M, Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage. J Bone Miner Res. 2008 Nov;23(11):1751-64 |
1 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
1 | J:208830 Lin SS, Tzeng BH, Lee KR, Smith RJ, Campbell KP, Chen CC, Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage. Proc Natl Acad Sci U S A. 2014 May 13;111(19):E1990-8 |
1 | J:352094 Liu C, Zhou N, Li N, Xu T, Chen X, Zhou H, Xie A, Liu H, Zhu L, Wang S, Xiao J, Disrupted tenogenesis in masseter as a potential cause of micrognathia. Int J Oral Sci. 2022 Oct 18;14(1):50 |
1 | J:91587 Mates L, Nicolae C, Morgelin M, Deak F, Kiss I, Aszodi A, Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities. Matrix Biol. 2004 Jun;23(3):195-204 |
1 | J:318774 Monemdjou R, Vasheghani F, Fahmi H, Perez G, Blati M, Taniguchi N, Lotz M, St-Arnaud R, Pelletier JP, Martel-Pelletier J, Beier F, Kapoor M, Association of cartilage-specific deletion of peroxisome proliferator-activated receptor gamma with abnormal endochondral ossification and impaired cartilage growth and development in a murine model. Arthritis Rheum. 2012 May;64(5):1551-61 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
2 | J:84742 Pavlov MI, Sautier JM, Oboeuf M, Asselin A, Berdal A, Chondrogenic differentiation during midfacial development in the mouse: in vivo and in vitro studies. Biol Cell. 2003;95(2):75-86 |
1* | J:356701 Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD, Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr;91(4):387-93 |
1* | J:120970 Sakai K, Kimata K, Sato T, Gotoh M, Narimatsu H, Shinomiya K, Watanabe H, Chondroitin sulfate N-acetylgalactosaminyltransferase-1 plays a critical role in chondroitin sulfate synthesis in cartilage. J Biol Chem. 2007 Feb 9;282(6):4152-61 |
1 | J:95068 Savontaus M, Rintala-Jamsa M, Morko J, Ronning O, Metsaranta M, Vuorio E, Abnormal craniofacial development and expression patterns of extracellular matrix components in transgenic Del1 mice harboring a deletion mutation in the type II collagen gene. Orthod Craniofac Res. 2004 Nov;7(4):216-26 |
1 | J:351035 Tan Z, Chen P, Dong X, Guo S, Leung VYL, Cheung JPY, Chan D, Richardson SM, Hoyland JA, To MKT, Cheah KSE, Progenitor-like cells contributing to cellular heterogeneity in the nucleus pulposus are lost in intervertebral disc degeneration. Cell Rep. 2024 Jun 25;43(6):114342 |
1 | J:264124 Tsushima H, Tang YJ, Puviindran V, Hsu SC, Nadesan P, Yu C, Zhang H, Mirando AJ, Hilton MJ, Alman BA, Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis. Development. 2018 Jul 9;145(13):dev162396 |
1 | J:112002 van der Weyden L, Wei L, Luo J, Yang X, Birk DE, Adams DJ, Bradley A, Chen Q, Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis. Am J Pathol. 2006 Aug;169(2):515-27 |
1 | J:173585 Wang L, Bresee CS, Jiang H, He W, Ren T, Schweitzer R, Brigande JV, Scleraxis is Required for Differentiation of the Stapedius and Tensor Tympani Tendons of the Middle Ear. J Assoc Res Otolaryngol. 2011 Aug;12(4):407-21 |
1 | J:113656 Wang Y, Nishida S, Sakata T, Elalieh HZ, Chang W, Halloran BP, Doty SB, Bikle DD, Insulin-like growth factor-I is essential for embryonic bone development. Endocrinology. 2006 Oct;147(10):4753-61 |
1 | J:202210 Zhang X, Ting K, Pathmanathan D, Ko T, Chen W, Chen F, Lee H, James AW, Siu RK, Shen J, Culiat CT, Soo C, Calvarial cleidocraniodysplasia-like defects with ENU-induced Nell-1 deficiency. J Craniofac Surg. 2012 Jan;23(1):61-6 |
Ace angiotensin I converting enzyme (Synonyms: CD143) | |
Results | Reference |
1* | J:218046 Cuffe JS, Walton SL, Steane SE, Singh RR, Simmons DG, Moritz KM, The effects of gestational age and maternal hypoxia on the placental renin angiotensin system in the mouse. Placenta. 2014 Nov;35(11):953-61 |
Ace2 angiotensin converting enzyme 2 (Synonyms: 2010305L05Rik) | |
Results | Reference |
1* | J:218046 Cuffe JS, Walton SL, Steane SE, Singh RR, Simmons DG, Moritz KM, The effects of gestational age and maternal hypoxia on the placental renin angiotensin system in the mouse. Placenta. 2014 Nov;35(11):953-61 |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
2 | J:361603 Scavuzzo MA, Szlachcic WJ, Hill MC, Ziojla NM, Teaw J, Carlson JC, Tiessen J, Chmielowiec J, Martin JF, Borowiak M, Pancreatic organogenesis mapped through space and time. Exp Mol Med. 2025 Feb;57(1):204-220 |
3* | J:183115 Song R, Preston G, Yosypiv IV, Ontogeny of angiotensin-converting enzyme 2. Pediatr Res. 2012 Jan;71(1):13-9 |
3* | J:237726 Wang L, Liang J, Leung PS, The ACE2/Ang-(1-7)/Mas Axis Regulates the Development of Pancreatic Endocrine Cells in Mouse Embryos. PLoS One. 2015;10(6):e0128216 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Acer1 alkaline ceramidase 1 (Synonyms: 2310024P18Rik, Asah3, Cer1) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Acer2 alkaline ceramidase 2 (Synonyms: 2410116I05Rik, Asah3l) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Acer3 alkaline ceramidase 3 (Synonyms: 1110057L18Rik, 5430429L08Rik, Phca) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Ache acetylcholinesterase | |
Results | Reference |
1 | J:117866 Warren M, Wang W, Spiden S, Chen-Murchie D, Tannahill D, Steel KP, Bradley A, A Sall4 mutant mouse model useful for studying the role of Sall4 in early embryonic development and organogenesis. Genesis. 2007 Jan;45(1):51-8 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Acin1 apoptotic chromatin condensation inducer 1 (Synonyms: 2610036I19Rik, 2610510L13Rik, Acinus, mKIAA0670) | |
Results | Reference |
1 | J:109567 Shen WB, Plachez C, Mongi AS, Richards LJ, Identification of candidate genes at the corticoseptal boundary during development. Gene Expr Patterns. 2006 Jun;6(5):471-81 |
Ackr3 atypical chemokine receptor 3 (Synonyms: Cmkor1, Cxcr7, Rdc1) | |
Results | Reference |
1 | J:345878 Fukuoka A, Wilson GJ, Pitmon E, Koumbas Foley L, Johnsson H, Pingen M, Graham GJ, Disruption of placental ACKR3 impairs growth and hematopoietic development of offspring. Development. 2024 Feb 15;151(4) |
1 | J:189818 Haege S, Einer C, Thiele S, Mueller W, Nietzsche S, Lupp A, Mackay F, Schulz S, Stumm R, CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney. PLoS One. 2012;7(8):e42814 |
1 | J:204198 Memi F, Abe P, Cariboni A, MacKay F, Parnavelas JG, Stumm R, CXC chemokine receptor 7 (CXCR7) affects the migration of GnRH neurons by regulating CXCL12 availability. J Neurosci. 2013 Oct 30;33(44):17527-37 |
1 | J:275611 Saaber F, Schutz D, Miess E, Abe P, Desikan S, Ashok Kumar P, Balk S, Huang K, Beaulieu JM, Schulz S, Stumm R, ACKR3 Regulation of Neuronal Migration Requires ACKR3 Phosphorylation, but Not beta-Arrestin. Cell Rep. 2019 Feb 5;26(6):1473-1488.e9 |
1 | J:124878 Sierro F, Biben C, Martinez-Munoz L, Mellado M, Ransohoff RM, Li M, Woehl B, Leung H, Groom J, Batten M, Harvey RP, Martinez-A C, Mackay CR, Mackay F, Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14759-64 |
1 | J:327277 Venkataramanappa S, Saaber F, Abe P, Schutz D, Kumar PA, Stumm R, Cxcr4 and Ackr3 regulate allocation of caudal ganglionic eminence-derived interneurons to superficial cortical layers. Cell Rep. 2022 Aug 2;40(5):111157 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Ackr4 atypical chemokine receptor 4 (Synonyms: A630091E18Rik, CCBP2, CCR11, Ccrl1, CCX-CKR, PPR1, VSHK1) | |
Results | Reference |
1 | J:237341 Houben A, Kostanova-Poliakova D, Weissenbock M, Graf J, Teufel S, von der Mark K, Hartmann C, beta-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis. Development. 2016 Oct 15;143(20):3826-3838 |
Acly ATP citrate lyase (Synonyms: A730098H14Rik) | |
Results | Reference |
1* | J:190090 Hasegawa S, Kume H, Iinuma S, Yamasaki M, Takahashi N, Fukui T, Acetoacetyl-CoA synthetase is essential for normal neuronal development. Biochem Biophys Res Commun. 2012 Oct 19;427(2):398-403 |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
1 | J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356 |
Acp5 acid phosphatase 5, tartrate resistant (Synonyms: TRACP, TRAP) | |
Results | Reference |
1* | J:288988 Coudert AE, Redelsperger F, Chabbi-Achengli Y, Vernochet C, Marty C, Decrouy X, Heidmann T, de Vernejoul MC, Dupressoir A, Role of the captured retroviral envelope syncytin-B gene in the fusion of osteoclast and giant cell precursors and in bone resorption, analyzed ex vivo and in vivo in syncytin-B knockout mice. Bone Rep. 2019 Dec;11:100214 |
1 | J:237341 Houben A, Kostanova-Poliakova D, Weissenbock M, Graf J, Teufel S, von der Mark K, Hartmann C, beta-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis. Development. 2016 Oct 15;143(20):3826-3838 |
1 | J:122952 Hung IH, Yu K, Lavine KJ, Ornitz DM, FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. Dev Biol. 2007 Jul 15;307(2):300-13 |
1 | J:119288 Jacob AL, Smith C, Partanen J, Ornitz DM, Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation. Dev Biol. 2006 Aug 15;296(2):315-28 |
1 | J:340406 Lai Y, Guo Y, Liao C, Mao C, Liu J, Ren C, Yang W, Luo L, Chen W, Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development. Sci Rep. 2023 Sep 13;13(1):15170 |
1 | J:119882 Liu Z, Lavine KJ, Hung IH, Ornitz DM, FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate. Dev Biol. 2007 Feb 1;302(1):80-91 |
2 | J:47204 Rice DP, Kim HJ, Thesleff I, Detection of gelatinase B expression reveals osteoclastic bone resorption as a feature of early calvarial bone development. Bone. 1997 Dec;21(6):479-86 |
1 | J:125052 Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H, Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification. Mol Cell Biol. 2007 Aug;27(16):5650-63 |
1* | J:104555 Viviano BL, Silverstein L, Pflederer C, Paine-Saunders S, Mills K, Saunders S, Altered hematopoiesis in glypican-3-deficient mice results in decreased osteoclast differentiation and a delay in endochondral ossification. Dev Biol. 2005 Jun 1;282(1):152-62 |
1 | J:292430 Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, Zhang X, Zhou Y, Yadav PS, Lin J, Wu N, Zhao L, Huang D, Zhou S, Su P, Yang Y, Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ss-catenin. Elife. 2020 Mar 18;9:e52779 |
1 | J:183128 Zhu CH, Morse LR, Battaglino RA, SNX10 is required for osteoclast formation and resorption activity. J Cell Biochem. 2012 May;113(5):1608-15 |
Acr acrosin prepropeptide (Synonyms: preproacrosin) | |
Results | Reference |
1 | J:158526 Naillat F, Prunskaite-Hyyrylainen R, Pietila I, Sormunen R, Jokela T, Shan J, Vainio SJ, Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development. Hum Mol Genet. 2010 Apr 15;19(8):1539-50 |
Acrv1 acrosomal vesicle protein 1 (Synonyms: Msa63, SP-10) | |
Results | Reference |
1 | J:104840 Grishina IB, Kim SY, Ferrara C, Makarenkova HP, Walden PD, BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling. Dev Biol. 2005 Dec 15;288(2):334-47 |
Acsl1 acyl-CoA synthetase long-chain family member 1 (Synonyms: Acas1, Facl2) | |
Results | Reference |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Acsl5 acyl-CoA synthetase long-chain family member 5 (Synonyms: 1700030F05Rik, Facl5) | |
Results | Reference |
1 | J:324530 Fonseca TL, Russo SC, Luongo C, Salvatore D, Bianco AC, Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 May 1;163(5) |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
Acsm4 acyl-CoA synthetase medium-chain family member 4 (Synonyms: O-MACS, OMACS) | |
Results | Reference |
1 | J:133461 Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH, Schier AF, Dulac C, Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 2008 Jan 10;57(1):41-55 |
1 | J:136319 Duggan CD, Demaria S, Baudhuin A, Stafford D, Ngai J, Foxg1 is required for development of the vertebrate olfactory system. J Neurosci. 2008 May 14;28(20):5229-39 |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Acss2 acyl-CoA synthetase short-chain family member 2 (Synonyms: ACAS, Acas1, Acas2, AceCS1, acetyl-CoA synthetase 1, Acs1) | |
Results | Reference |
1* | J:77316 Loikkanen I, Haghighi S, Vainio S, Pajunen A, Expression of cytosolic acetyl-CoA synthetase gene is developmentally regulated. Mech Dev. 2002 Jul;115(1-2):139-41 |
Acta1 actin alpha 1, skeletal muscle (Synonyms: Acts, Actsk-1) | |
Results | Reference |
1 | J:245883 Aldeiri B, Roostalu U, Albertini A, Wong J, Morabito A, Cossu G, Transgelin-expressing myofibroblasts orchestrate ventral midline closure through TGFbeta signalling. Development. 2017 Sep 15;144(18):3336-3348 |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1 | J:320322 Chen WC, Zhang Y, Ma D, Ma XJ, Shou WN, Huang GY, Bmp2 regulates the interaction between EPDCs and myocytes in cardiac OFT. Med Hypotheses. 2012 Aug;79(2):174-7 |
1 | J:60987 Kablar B, Tajbakhsh S, Rudnicki MA, Transdifferentiation of esophageal smooth to skeletal muscle is myogenic bHLH factor-dependent. Development. 2000 Apr;127(8):1627-39 |
1 | J:173588 Kanazawa T, Ichii O, Otsuka S, Namiki Y, Hashimoto Y, Kon Y, Hepatocyte nuclear factor 4 alpha is associated with mesenchymal-epithelial transition in developing kidneys of C57BL/6 mice. J Vet Med Sci. 2011 May;73(5):601-7 |
1 | J:98521 Mailleux AA, Kelly R, Veltmaat JM, De Langhe SP, Zaffran S, Thiery JP, Bellusci S, Fgf10 expression identifies parabronchial smooth muscle cell progenitors and is required for their entry into the smooth muscle cell lineage. Development. 2005 May;132(9):2157-66 |
1 | J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97 |
Acta2 actin alpha 2, smooth muscle, aorta (Synonyms: 0610041G09Rik, Actvs, alphaSMA, a-SMA, SMAalpha, SMalphaA) | |
Results | Reference |
1 | J:219809 Afelik S, Pool B, Schmerr M, Penton C, Jensen J, Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development. Dev Biol. 2015 Mar 15;399(2):204-17 |
1* | J:324263 Aksel S, Cao M, Derpinghaus A, Baskin LS, Cunha GR, Ontogeny of mouse Sertoli, Leydig and peritubular myoid cells from embryonic day 10 to adulthood. Differentiation. 2022 Mar 7; |
1 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1 | J:237340 Ben Shoham A, Rot C, Stern T, Krief S, Akiva A, Dadosh T, Sabany H, Lu Y, Kadler KE, Zelzer E, Deposition of collagen type I onto skeletal endothelium reveals a new role for blood vessels in regulating bone morphology. Development. 2016 Nov 01;143(21):3933-3943 |
1 | J:240616 Benito-Jardon M, Klapproth S, Gimeno-LLuch I, Petzold T, Bharadwaj M, Muller DJ, Zuchtriegel G, Reichel CA, Costell M, The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes. Elife. 2017 Jan 16;6:e22264 |
1* | J:162756 Bergwerff M, DeRuiter MC, Hall S, Poelmann RE, Gittenberger-de Groot AC, Unique vascular morphology of the fourth aortic arches: possible implications for pathogenesis of type-B aortic arch interruption and anomalous right subclavian artery. Cardiovasc Res. 1999 Oct;44(1):185-96 |
1 | J:262819 Bohnenpoll T, Feraric S, Nattkemper M, Weiss AC, Rudat C, Meuser M, Trowe MO, Kispert A, Diversification of Cell Lineages in Ureter Development. J Am Soc Nephrol. 2017 Jun;28(6):1792-1801 |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1 | J:336423 Bottasso-Arias N, Burra K, Sinner D, Riede T, Disruption of BMP4 signaling is associated with laryngeal birth defects in a mouse model. Dev Biol. 2023 May 23;500:10-21 |
1 | J:310741 Briot A, Jaroszewicz A, Warren CM, Lu J, Touma M, Rudat C, Hofmann JJ, Airik R, Weinmaster G, Lyons K, Wang Y, Kispert A, Pellegrini M, Iruela-Arispe ML, Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Dev Cell. 2014 Dec 22;31(6):707-21 |
1 | J:196836 Cammas L, Wolfe J, Choi SY, Dedhar S, Beggs HE, Integrin-linked kinase deletion in the developing lens leads to capsule rupture, impaired fiber migration and non-apoptotic epithelial cell death. Invest Ophthalmol Vis Sci. 2012;53(6):3067-81 |
1 | J:180115 Cao XM, Yang YP, Li HR, Cui HL, Ya J, Morphology of the developing muscularis externa in the mouse esophagus. Dis Esophagus. 2012 Jan;25(1):10-6 |
1 | J:196361 Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnani MG, Messina G, Cossu G, Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory. Dev Cell. 2013 Mar 25;24(6):586-99 |
1 | J:192176 Casanova JC, Travisano S, de la Pompa JL, Epithelial-to-mesenchymal transition in epicardium is independent of snail1. Genesis. 2013 Jan;51(1):32-40 |
1 | J:233304 Cha B, Geng X, Mahamud MR, Fu J, Mukherjee A, Kim Y, Jho EH, Kim TH, Kahn ML, Xia L, Dixon JB, Chen H, Srinivasan RS, Mechanotransduction activates canonical Wnt/beta-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves. Genes Dev. 2016 Jun 15;30(12):1454-69 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:98474 Chen C, Chen H, Sun J, Bringas P Jr, Chen Y, Warburton D, Shi W, Smad1 expression and function during mouse embryonic lung branching morphogenesis. Am J Physiol Lung Cell Mol Physiol. 2005 Jun;288(6):L1033-9 |
1 | J:339854 Chen SY, Liu FC, The Fgf9-Nolz1-Wnt2 axis regulates morphogenesis of the lung. Development. 2023 Aug 15;150(16):dev201827 |
1 | J:314282 Chevalier NR, Ammouche Y, Gomis A, Langlois L, Guilbert T, Bourdoncle P, Dufour S, A neural crest cell isotropic-to-nematic phase transition in the developing mammalian gut. Commun Biol. 2021 Jun 23;4(1):770 |
1 | J:283675 Comai G, Heude E, Mella S, Paisant S, Pala F, Gallardo M, Langa F, Kardon G, Gopalakrishnan S, Tajbakhsh S, A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle. Elife. 2019 Sep 19;8:e47460 |
1 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1 | J:157519 Desai VD, Wang Y, Simirskii VN, Duncan MK, CD44 expression is developmentally regulated in the mouse lens and increases in the lens epithelium after injury. Differentiation. 2010 Feb;79(2):111-9 |
1 | J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767 |
1* | J:319356 Dong K, Shen J, He X, Hu G, Wang L, Osman I, Bunting KM, Dixon-Melvin R, Zheng Z, Xin H, Xiang M, Vazdarjanova A, Fulton DJR, Zhou J, CARMN Is an Evolutionarily Conserved Smooth Muscle Cell-Specific LncRNA That Maintains Contractile Phenotype by Binding Myocardin. Circulation. 2021 Dec 7;144(23):1856-1875 |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82 |
1 | J:316977 Endale M, Ahlfeld S, Bao E, Chen X, Green J, Bess Z, Weirauch MT, Xu Y, Perl AK, Temporal, spatial, and phenotypical changes of PDGFRalpha expressing fibroblasts during late lung development. Dev Biol. 2017 May 15;425(2):161-175 |
1 | J:226950 Fogelgren B, Polgar N, Lui VH, Lee AJ, Tamashiro KK, Napoli JA, Walton CB, Zuo X, Lipschutz JH, Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions. PLoS One. 2015;10(6):e0129346 |
1 | J:163382 Foronjy R, Imai K, Shiomi T, Mercer B, Sklepkiewicz P, Thankachen J, Bodine P, D'Armiento J, The divergent roles of secreted frizzled related protein-1 (SFRP1) in lung morphogenesis and emphysema. Am J Pathol. 2010 Aug;177(2):598-607 |
1 | J:93083 Fraidenraich D, Stillwell E, Romero E, Wilkes D, Manova K, Basson CT, Benezra R, Rescue of cardiac defects in id knockout embryos by injection of embryonic stem cells. Science. 2004 Oct 8;306(5694):247-52 |
1 | J:339855 Gannoun L, De Schrevel C, Belle M, Dauguet N, Achouri Y, Loriot A, Vanderaa C, Cordi S, Dili A, Heremans Y, Rooman I, Leclercq IA, Jacquemin P, Gatto L, Lemaigre FP, Axon guidance genes control hepatic artery development. Development. 2023 Aug 15;150(16):dev201642 |
1 | J:228882 Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS, Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016 Jan 1;409(1):218-33 |
1* | J:260471 Gerhardt B, Leesman L, Burra K, Snowball J, Rosenzweig R, Guzman N, Ambalavanan M, Sinner D, Notum attenuates Wnt/beta-catenin signaling to promote tracheal cartilage patterning. Dev Biol. 2018 Apr 1;436(1):14-27 |
1* | J:317799 Gervais EM, Sequeira SJ, Wang W, Abraham S, Kim JH, Leonard D, DeSantis KA, Larsen M, Par-1b is required for morphogenesis and differentiation of myoepithelial cells during salivary gland development. Organogenesis. 2016 Oct;12(4):194-216 |
1 | J:139005 Geske MJ, Zhang X, Patel KK, Ornitz DM, Stappenbeck TS, Fgf9 signaling regulates small intestinal elongation and mesenchymal development. Development. 2008 Sep;135(17):2959-68 |
2 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:280117 Gong X, Guo X, Huang R, Liao H, Zhang Q, Yan J, Luo L, Zhang Q, Qiu A, Sun Y, Liang X, Expression of ILK in renal stroma is essential for multiple aspects of renal development. Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F374-F385 |
1 | J:225351 Gopalakrishnan S, Comai G, Sambasivan R, Francou A, Kelly RG, Tajbakhsh S, A Cranial Mesoderm Origin for Esophagus Striated Muscles. Dev Cell. 2015 Sep 28;34(6):694-704 |
1* | J:137168 Gordon EJ, Gale NW, Harvey NL, Expression of the hyaluronan receptor LYVE-1 is not restricted to the lymphatic vasculature; LYVE-1 is also expressed on embryonic blood vessels. Dev Dyn. 2008 Jul;237(7):1901-9 |
2 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
1 | J:189012 Greif DM, Kumar M, Lighthouse JK, Hum J, An A, Ding L, Red-Horse K, Espinoza FH, Olson L, Offermanns S, Krasnow MA, Radial construction of an arterial wall. Dev Cell. 2012 Sep 11;23(3):482-93 |
1 | J:104840 Grishina IB, Kim SY, Ferrara C, Makarenkova HP, Walden PD, BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling. Dev Biol. 2005 Dec 15;288(2):334-47 |
1* | J:231595 Gurdziel K, Vogt KR, Walton KD, Schneider GK, Gumucio DL, Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. Dev Dyn. 2016 May;245(5):614-26 |
1* | J:83560 Hamilton TG, Klinghoffer RA, Corrin PD, Soriano P, Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms. Mol Cell Biol. 2003 Jun;23(11):4013-25 |
1 | J:342844 Harvey AB, Wolters RA, Deepe RN, Tarolli HG, Drummond JR, Trouten A, Zandi A, Barth JL, Mukherjee R, Romeo MJ, Vaena SG, Tao G, Muise-Helmericks R, Ramos PS, Norris RA, Wessels A, Epicardial deletion of Sox9 leads to myxomatous valve degeneration and identifies Cd109 as a novel gene associated with valve development. J Mol Cell Cardiol. 2023 Nov 5;186:16-30 |
1 | J:354192 He H, Bell SM, Davis AK, Zhao S, Sridharan A, Na CL, Guo M, Xu Y, Snowball J, Swarr DT, Zacharias WJ, Whitsett JA, PRDM3/16 regulate chromatin accessibility required for NKX2-1 mediated alveolar epithelial differentiation and function. Nat Commun. 2024 Sep 16;15(1):8112 |
1 | J:343095 Honeycutt SE, N'Guetta PY, Hardesty DM, Xiong Y, Cooper SL, Stevenson MJ, O'Brien LL, Netrin 1 directs vascular patterning and maturity in the developing kidney. Development. 2023 Nov 15;150(22) |
1* | J:187741 Hu JK, McGlinn E, Harfe BD, Kardon G, Tabin CJ, Autonomous and nonautonomous roles of Hedgehog signaling in regulating limb muscle formation. Genes Dev. 2012 Sep 15;26(18):2088-102 |
1 | J:321245 Hu S, Mahadevan A, Elysee IF, Choi J, Souchet NR, Bae GH, Taboada AK, Sanketi B, Duhamel GE, Sevier CS, Tao G, Kurpios NA, The asymmetric Pitx2 gene regulates gut muscular-lacteal development and protects against fatty liver disease. Cell Rep. 2021 Nov 23;37(8):110030 |
1 | J:150516 Hu Z, Wang C, Xiao Y, Sheng N, Chen Y, Xu Y, Zhang L, Mo W, Jing N, Hu G, NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development. J Cell Sci. 2009 Apr 15;122(Pt 8):1145-54 |
1 | J:170883 Huang J, Davis EC, Chapman SL, Budatha M, Marmorstein LY, Word RA, Yanagisawa H, Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progression. Circ Res. 2010 Feb 19;106(3):583-92 |
1 | J:239651 Hurtado R, Zewdu R, Mtui J, Liang C, Aho R, Kurylo C, Selleri L, Herzlinger D, Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning. Development. 2015 Aug 01;142(15):2653-64 |
1 | J:284488 Huycke TR, Miller BM, Gill HK, Nerurkar NL, Sprinzak D, Mahadevan L, Tabin CJ, Genetic and Mechanical Regulation of Intestinal Smooth Muscle Development. Cell. 2019 Sep 19;179(1):90-105.e21 |
3 | J:242713 Ikeda Y, Zabbarova I, Schaefer CM, Bushnell D, De Groat WC, Kanai A, Bates CM, Fgfr2 is integral for bladder mesenchyme patterning and function. Am J Physiol Renal Physiol. 2017 Apr 01;312(4):F607-F618 |
1 | J:216228 Inoue S, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y, New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet. 2014 Dec 15;23(24):6553-66 |
1 | J:108713 Itaranta P, Chi L, Seppanen T, Niku M, Tuukkanen J, Peltoketo H, Vainio S, Wnt-4 signaling is involved in the control of smooth muscle cell fate via Bmp-4 in the medullary stroma of the developing kidney. Dev Biol. 2006 May 15;293(2):473-83 |
1 | J:289321 Jangphattananont N, Sato H, Imamura R, Sakai K, Terakado Y, Murakami K, Barker N, Oshima H, Oshima M, Takagi J, Kato Y, Yano S, Matsumoto K, Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach. Int J Mol Sci. 2019 Jun 17;20(12):2955 |
1* | J:225747 Jayewickreme CD, Shivdasani RA, Control of stomach smooth muscle development and intestinal rotation by transcription factor BARX1. Dev Biol. 2015 Sep 1;405(1):21-32 |
1* | J:193107 Jin C, Chen J, Meng Q, Carreira V, Tam NN, Geh E, Karyala S, Ho SM, Zhou X, Medvedovic M, Xia Y, Deciphering gene expression program of MAP3K1 in mouse eyelid morphogenesis. Dev Biol. 2013 Feb 1;374(1):96-107 |
1 | J:254094 Jing X, Gao Y, Xiao S, Qin Q, Wei X, Yan Y, Wu L, Deng S, Du J, Liu Y, She Q, Hypoxia induced the differentiation of Tbx18-positive epicardial cells to CoSMCs. Sci Rep. 2016 Jul 26;6:30468 |
1* | J:139639 Juszynski M, Ciszek B, Stachurska E, Jablonska A, Ratajska A, Development of lymphatic vessels in mouse embryonic and early postnatal hearts. Dev Dyn. 2008 Sep 24;237(10):2973-2986 |
1 | J:60987 Kablar B, Tajbakhsh S, Rudnicki MA, Transdifferentiation of esophageal smooth to skeletal muscle is myogenic bHLH factor-dependent. Development. 2000 Apr;127(8):1627-39 |
1 | J:316525 Kaku Y, Ohmori T, Kudo K, Fujimura S, Suzuki K, Evans SM, Kawakami Y, Nishinakamura R, Islet1 deletion causes kidney agenesis and hydroureter resembling CAKUT. J Am Soc Nephrol. 2013 Jul;24(8):1242-9 |
1 | J:63212 Karlsson L, Lindahl P, Heath JK, Betsholtz C, Abnormal gastrointestinal development in PDGF-A and PDGFR-(alpha) deficient mice implicates a novel mesenchymal structure with putative instructive properties in villus morphogenesis. Development. 2000 Aug;127(16):3457-66 |
1 | J:239279 Kidoya H, Naito H, Muramatsu F, Yamakawa D, Jia W, Ikawa M, Sonobe T, Tsuchimochi H, Shirai M, Adams RH, Fukamizu A, Takakura N, APJ Regulates Parallel Alignment of Arteries and Veins in the Skin. Dev Cell. 2015 May 04;33(3):247-59 |
1 | J:299734 Kishimoto K, Furukawa KT, Luz-Madrigal A, Yamaoka A, Matsuoka C, Habu M, Alev C, Zorn AM, Morimoto M, Bidirectional Wnt signaling between endoderm and mesoderm confers tracheal identity in mouse and human cells. Nat Commun. 2020 Aug 27;11(1):4159 |
2 | J:266265 Kishimoto K, Tamura M, Nishita M, Minami Y, Yamaoka A, Abe T, Shigeta M, Morimoto M, Synchronized mesenchymal cell polarization and differentiation shape the formation of the murine trachea and esophagus. Nat Commun. 2018 Jul 19;9(1):2816 |
1 | J:353381 Kostic L, Leung C, Ahmad Murad K, Kancheva S, Perna S, Lee B, Barker N, Lgr5 marks stem/progenitor cells contributing to epithelial and muscle development in the mouse esophagus. Nat Commun. 2024 Aug 21;15(1):7145 |
1 | J:123073 Kruger I, Vollmer M, Simmons DG, Elsasser HP, Philipsen S, Suske G, Sp1/Sp3 compound heterozygous mice are not viable: Impaired erythropoiesis and severe placental defects. Dev Dyn. 2007 Aug;236(8):2235-44 |
1* | J:82571 Kruithof BP, Van Den Hoff MJ, Tesink-Taekema S, Moorman AF, Recruitment of intra- and extracardiac cells into the myocardial lineage during mouse development. Anat Rec A Discov Mol Cell Evol Biol. 2003 Apr;271(2):303-14 |
2 | J:342552 Kulikauskas MR, Oatley M, Yu T, Liu Z, Matsumura L, Kidder E, Ruter D, Bautch VL, Endothelial cell SMAD6 balances Alk1 function to regulate adherens junctions and hepatic vascular development. Development. 2023 Nov 1;150(21) |
3 | J:257613 Kuony A, Michon F, Epithelial Markers aSMA, Krt14, and Krt19 Unveil Elements of Murine Lacrimal Gland Morphogenesis and Maturation. Front Physiol. 2017;8:739 |
1 | J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:159810 Leclair RJ, Wang Q, Benson MA, Prudovsky I, Lindner V, Intracellular localization of Cthrc1 characterizes differentiated smooth muscle. Arterioscler Thromb Vasc Biol. 2008 Jul;28(7):1332-8 |
1* | J:250161 Lee AJ, Polgar N, Napoli JA, Lui VH, Tamashiro KK, Fujimoto BA, Thompson KS, Fogelgren B, Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy. Sci Rep. 2016 Aug 11;6:31137 |
1* | J:306217 Lee H, Ko HW, Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development. BMB Rep. 2020 Jul;53(7):367-372 |
1* | J:98561 Lee SK, Kim YS, Lee YJ, Lee SS, Song IS, Park SC, Chi JG, Chung SI, Transglutaminase 2 expression in the salivary myoepithelial cells of mouse embryo. Arch Oral Biol. 2005 Mar;50(3):301-8 |
1 | J:257184 Leid J, Carrelha J, Boukarabila H, Epelman S, Jacobsen SE, Lavine KJ, Primitive Embryonic Macrophages are Required for Coronary Development and Maturation. Circ Res. 2016 May 13;118(10):1498-511 |
1 | J:200617 Li A, Hardy R, Stoner S, Tuckermann J, Seibel M, Zhou H, Deletion of mesenchymal glucocorticoid receptor attenuates embryonic lung development and abdominal wall closure. PLoS One. 2013;8(5):e63578 |
1 | J:250062 Li A, Ma S, Smith SM, Lee MK, Fischer A, Borok Z, Bellusci S, Li C, Minoo P, Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate. BMC Biol. 2016 Mar 16;14:19 |
1 | J:335070 Li MH, Kuetemeyer JM, Yallowitz AR, Wellik DM, Characterization of a novel Hoxa5eGFP mouse line. Dev Dyn. 2023 Apr;252(4):536-546 |
1* | J:75939 Li WE, Waldo K, Linask KL, Chen T, Wessels A, Parmacek MS, Kirby ML, Lo CW, An essential role for connexin43 gap junctions in mouse coronary artery development. Development. 2002 Apr;129(8):2031-42 |
2 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
1 | J:322701 Liu Y, Chen Q, Jeong HW, Koh BI, Watson EC, Xu C, Stehling M, Zhou B, Adams RH, A specialized bone marrow microenvironment for fetal haematopoiesis. Nat Commun. 2022 Mar 14;13(1):1327 |
1 | J:184582 Lopes M, Gooupille O, Saint Cloment C, Robert B, Msx1 is expressed in retina endothelial cells at artery branching sites. Biol Open. 2012 Apr 15;1(4):376-384 |
1 | J:315454 Loscertales M, Nicolaou F, Jeanne M, Longoni M, Gould DB, Sun Y, Maalouf FI, Nagy N, Donahoe PK, Type IV collagen drives alveolar epithelial-endothelial association and the morphogenetic movements of septation. BMC Biol. 2016 Jul 13;14:59 |
1 | J:118250 Mahoney ZX, Sammut B, Xavier RJ, Cunningham J, Go G, Brim KL, Stappenbeck TS, Miner JH, Swat W, Discs-large homolog 1 regulates smooth muscle orientation in the mouse ureter. Proc Natl Acad Sci U S A. 2006 Dec 26;103(52):19872-7 |
1 | J:207861 Manthey AL, Lachke SA, FitzGerald PG, Mason RW, Scheiblin DA, McDonald JH, Duncan MK, Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development. Mech Dev. 2014 Feb;131:86-110 |
1 | J:160363 Mao J, Kim BM, Rajurkar M, Shivdasani RA, McMahon AP, Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract. Development. 2010 May;137(10):1721-9 |
2 | J:202129 Martin E, Caubit X, Airik R, Vola C, Fatmi A, Kispert A, Fasano L, TSHZ3 and SOX9 regulate the timing of smooth muscle cell differentiation in the ureter by reducing myocardin activity. PLoS One. 2013;8(5):e63721 |
1 | J:166573 Martinez-Estrada OM, Lettice LA, Essafi A, Guadix JA, Slight J, Velecela V, Hall E, Reichmann J, Devenney PS, Hohenstein P, Hosen N, Hill RE, Munoz-Chapuli R, Hastie ND, Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin. Nat Genet. 2010 Jan;42(1):89-93 |
1* | J:170660 Matsuo A, Yoshida T, Yasukawa T, Miki R, Kume K, Kume S, Epiplakin1 is expressed in the cholangiocyte lineage cells in normal liver and adult progenitor cells in injured liver. Gene Expr Patterns. 2011 Mar-Apr;11(3-4):255-62 |
1* | J:148803 McCulloch DR, Le Goff C, Bhatt S, Dixon LJ, Sandy JD, Apte SS, Adamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues. Gene Expr Patterns. 2009 Jun;9(5):314-23 |
1 | J:330583 McKey J, Anbarci DN, Bunce C, Ontiveros AE, Behringer RR, Capel B, Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii. Elife. 2022 Sep 27;11:e81088 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:156970 Mikels A, Minami Y, Nusse R, Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling. J Biol Chem. 2009 Oct 30;284(44):30167-76 |
1 | J:232801 Misra A, Sheikh AQ, Kumar A, Luo J, Zhang J, Hinton RB, Smoot L, Kaplan P, Urban Z, Qyang Y, Tellides G, Greif DM, Integrin beta3 inhibition is a therapeutic strategy for supravalvular aortic stenosis. J Exp Med. 2016 Mar 7;213(3):451-63 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
1 | J:264719 Moghieb A, Clair G, Mitchell HD, Kitzmiller J, Zink EM, Kim YM, Petyuk V, Shukla A, Moore RJ, Metz TO, Carson J, McDermott JE, Corley RA, Whitsett JA, Ansong C, Time-resolved proteome profiling of normal lung development. Am J Physiol Lung Cell Mol Physiol. 2018 Jul 1;315(1):L11-L24 |
1 | J:156690 Morimoto M, Liu Z, Cheng HT, Winters N, Bader D, Kopan R, Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate. J Cell Sci. 2010 Jan 15;123(Pt 2):213-24 |
1 | J:358157 N'Guetta PY, McLarnon SR, Tassou A, Geron M, Shirvan S, Hill RZ, Scherrer G, O'Brien LL, Comprehensive mapping of sensory and sympathetic innervation of the developing kidney. Cell Rep. 2024 Oct 22;43(10):114860 |
1 | J:329397 Nadeem T, Bommareddy A, Bolarinwa L, Cuervo H, Pericyte dynamics in the mouse germinal matrix angiogenesis. FASEB J. 2022 Jun;36(6):e22339 |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
1 | J:348078 Nie X, Abbasi Y, Chung MK, Piezo1 and Piezo2 collectively regulate jawbone development. Development. 2024 May 1;151(9):dev202386 |
1 | J:157941 Nie X, Sun J, Gordon RE, Cai CL, Xu PX, SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation. Development. 2010 Mar;137(5):755-65 |
1 | J:243620 Nonomura K, Woo SH, Chang RB, Gillich A, Qiu Z, Francisco AG, Ranade SS, Liberles SD, Patapoutian A, Piezo2 senses airway stretch and mediates lung inflation-induced apnoea. Nature. 2017 Jan 12;541(7636):176-181 |
1 | J:149138 Norrmen C, Ivanov KI, Cheng J, Zangger N, Delorenzi M, Jaquet M, Miura N, Puolakkainen P, Horsley V, Hu J, Augustin HG, Yla-Herttuala S, Alitalo K, Petrova TV, FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1. J Cell Biol. 2009 May 4;185(3):439-57 |
1* | J:56682 Ohlsson R, Falck P, Hellstrom M, Lindahl P, Bostrom H, Franklin G, Ahrlund-Richter L, Pollard J, Soriano P, Betsholtz C, PDGFB regulates the development of the labyrinthine layer of the mouse fetal placenta. Dev Biol. 1999 Aug 1;212(1):124-36 |
2 | J:146617 Olson LE, Soriano P, Increased PDGFRalpha activation disrupts connective tissue development and drives systemic fibrosis. Dev Cell. 2009 Feb;16(2):303-13 |
1 | J:185279 Paces-Fessy M, Fabre M, Lesaulnier C, Cereghini S, Hnf1b and Pax2 cooperate to control different pathways in kidney and ureter morphogenesis. Hum Mol Genet. 2012 Jul 15;21(14):3143-55 |
1* | J:353621 Patel VN, Aure MH, Choi SH, Ball JR, Lane ED, Wang Z, Xu Y, Zheng C, Liu X, Martin D, Pailin JY, Prochazkova M, Kulkarni AB, van Kuppevelt TH, Ambudkar IS, Liu J, Hoffman MP, Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation. Nat Commun. 2024 Aug 31;15(1):7584 |
1 | J:236785 Pathania M, Wang Y, Simirskii VN, Duncan MK, beta1-integrin controls cell fate specification in early lens development. Differentiation. 2016 Oct - Nov;92(4):133-147 |
1 | J:308707 Paulson D, Harms R, Ward C, Latterell M, Pazour GJ, Fink DM, Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation. Front Cell Dev Biol. 2021;9:672625 |
1 | J:60124 Pitera JE, Smith VV, Thorogood P, Milla PJ, Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code. Gastroenterology. 1999 Dec;117(6):1339-51 |
1 | J:159267 Plante J, Simard M, Rantakari P, Cote M, Provost PR, Poutanen M, Tremblay Y, Epithelial cells are the major site of hydroxysteroid (17beta) dehydrogenase 2 and androgen receptor expression in fetal mouse lungs during the period overlapping the surge of surfactant. J Steroid Biochem Mol Biol. 2009 Nov;117(4-5):139-45 |
1 | J:221833 Prakash A, Udager AM, Saenz DA, Gumucio DL, Roles for Nkx2-5 and Gata3 in the ontogeny of the murine smooth muscle gastric ligaments. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 15;307(4):G430-6 |
1 | J:177268 Radzikinas K, Aven L, Jiang Z, Tran T, Paez-Cortez J, Boppidi K, Lu J, Fine A, Ai X, A Shh/miR-206/BDNF Cascade Coordinates Innervation and Formation of Airway Smooth Muscle. J Neurosci. 2011 Oct 26;31(43):15407-15 |
1 | J:224142 Reginensi A, Hoshi M, Boualia SK, Bouchard M, Jain S, McNeill H, Yap and Taz are required for Ret-dependent urinary tract morphogenesis. Development. 2015 Aug 1;142(15):2696-703 |
1 | J:296443 Rondon-Galeano M, Skoczylas R, Bower NI, Simons C, Gordon E, Francois M, Koltowska K, Hogan BM, MAFB modulates the maturation of lymphatic vascular networks in mice. Dev Dyn. 2020 Oct;249(10):1201-1216 |
1 | J:292237 Roostalu U, Aldeiri B, Albertini A, Humphreys N, Simonsen-Jackson M, Wong JKF, Cossu G, Distinct Cellular Mechanisms Underlie Smooth Muscle Turnover in Vascular Development and Repair. Circ Res. 2018 Jan 19;122(2):267-281 |
1 | J:277847 Roux M, Bouchard M, Kmita M, Multifaceted Hoxa13 function in urogenital development underlies the Hand-Foot-Genital Syndrome. Hum Mol Genet. 2019 May 15;28(10):1671-1681 |
1 | J:127938 Sauter A, Machura K, Neubauer B, Kurtz A, Wagner C, Development of renin expression in the mouse kidney. Kidney Int. 2008 Jan;73(1):43-51 |
1 | J:70875 Sequeira Lopez ML, Pentz ES, Robert B, Abrahamson DR, Gomez RA, Embryonic origin and lineage of juxtaglomerular cells. Am J Physiol Renal Physiol. 2001 Aug;281(2):F345-56 |
1 | J:314585 Shadad O, Chaulagain R, Luukko K, Kettunen P, Establishment of tooth blood supply and innervation is developmentally regulated and takes place through differential patterning processes. J Anat. 2019 Apr;234(4):465-479 |
1 | J:188834 Shen D, Li J, Lepore JJ, Anderson TJ, Sinha S, Lin AY, Cheng L, Cohen ED, Roberts JD Jr, Dedhar S, Parmacek MS, Gerszten RE, Aortic aneurysm generation in mice with targeted deletion of integrin-linked kinase in vascular smooth muscle cells. Circ Res. 2011 Sep 2;109(6):616-28 |
1 | J:122566 Simirskii VN, Wang Y, Duncan MK, Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype. Dev Biol. 2007 Jun 15;306(2):658-68 |
1 | J:356070 Song EC, Min S, Oyelakin A, Smalley K, Bard JE, Liao L, Xu J, Romano RA, Genetic and scRNA-seq Analysis Reveals Distinct Cell Populations that Contribute to Salivary Gland Development and Maintenance. Sci Rep. 2018 Sep 19;8(1):14043 |
1 | J:164627 Sparrow DB, Boyle SC, Sams RS, Mazuruk B, Zhang L, Moeckel GW, Dunwoodie SL, de Caestecker MP, Placental insufficiency associated with loss of Cited1 causes renal medullary dysplasia. J Am Soc Nephrol. 2009 Apr;20(4):777-86 |
1 | J:361958 Straube P, Beckers A, Jany UWH, Bergmann F, Ludtke TH, Rudat C, Trowe MO, Peters I, Klopf MG, Mamo TM, Kispert A, Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter. Development. 2025 Feb 1;152(3) |
1 | J:154910 Sugiyama Y, Akimoto K, Robinson ML, Ohno S, Quinlan RA, A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol. 2009 Dec 15;336(2):246-56 |
1 | J:98520 Takamoto N, You LR, Moses K, Chiang C, Zimmer WE, Schwartz RJ, Demayo FJ, Tsai MJ, Tsai SY, COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development. 2005 May;132(9):2179-89 |
1 | J:338930 Tarnick J, Elhendawi M, Holland I, Chang Z, Davies JA, Innervation of the developing kidney in vivo and in vitro. Biol Open. 2023 Aug 15;12(8) |
1* | J:325177 Thiemann RF, Varney S, Moskwa N, Lamar J, Larsen M, LaFlamme SE, Regulation of myoepithelial differentiation. PLoS One. 2022;17(5):e0268668 |
1 | J:299728 Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL, Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. Elife. 2019 Dec 4;8:e49977 |
2 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
1 | J:266086 Tsukiji N, Inoue O, Morimoto M, Tatsumi N, Nagatomo H, Ueta K, Shirai T, Sasaki T, Otake S, Tamura S, Tachibana T, Okabe M, Hirashima M, Ozaki Y, Suzuki-Inoue K, Platelets play an essential role in murine lung development through Clec-2/podoplanin interaction. Blood. 2018 Sep 13;132(11):1167-1179 |
1 | J:228275 Udager AM, Prakash A, Saenz DA, Schinke M, Moriguchi T, Jay PY, Lim KC, Engel JD, Gumucio DL, Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3. Gastroenterology. 2014 Jan;146(1):157-65.e10 |
1 | J:266598 Ustiyan V, Bolte C, Zhang Y, Han L, Xu Y, Yutzey KE, Zorn AM, Kalin TV, Shannon JM, Kalinichenko VV, FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme. Dev Biol. 2018 Nov 1;443(1):50-63 |
1* | J:152859 Varadkar PA, Kraman M, McCright B, Generation of mice that conditionally express the activation domain of Notch2. Genesis. 2009 Aug;47(8):573-8 |
1 | J:85775 Wagner TE, Frevert CW, Herzog EL, Schnapp LM, Expression of the integrin subunit alpha8 in murine lung development. J Histochem Cytochem. 2003 Oct;51(10):1307-15 |
1 | J:239983 Walton KD, Whidden M, Kolterud A, Shoffner SK, Czerwinski MJ, Kushwaha J, Parmar N, Chandhrasekhar D, Freddo AM, Schnell S, Gumucio DL, Villification in the mouse: Bmp signals control intestinal villus patterning. Development. 2016 Feb 01;143(3):427-36 |
2 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
2 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:286995 Wang YQ, Cheng JM, Wen Q, Tang JX, Li J, Chen SR, Liu YX, An exploration of the role of Sertoli cells on fetal testis development using cell ablation strategy. Mol Reprod Dev. 2020 Feb;87(2):223-230 |
1* | J:117226 Wei K, Che N, Chen F, Myocardin-related transcription factor B is required for normal mouse vascular development and smooth muscle gene expression. Dev Dyn. 2007 Feb;236(2):416-25 |
2 | J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26 |
1 | J:251156 Wen Q, Wang Y, Tang J, Cheng CY, Liu YX, Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development. PLoS One. 2016;11(12):e0167920 |
1 | J:102947 Wilm B, Ipenberg A, Hastie ND, Burch JB, Bader DM, The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature. Development. 2005 Dec;132(23):5317-28 |
1* | J:175387 Wu X, Xu K, Zhang L, Deng Y, Lee P, Shapiro E, Monaco M, Makarenkova HP, Li J, Lepor H, Grishina I, Differentiation of the ductal epithelium and smooth muscle in the prostate gland are regulated by the Notch/PTEN-dependent mechanism. Dev Biol. 2011 Aug 15;356(2):337-49 |
1 | J:342871 Xiang J, Pompetti AJ, Faranda AP, Wang Y, Novo SG, Li DW, Duncan MK, ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment. Cells. 2023 Nov 16;12(22) |
1 | J:331058 Xu J, Liu H, Lan Y, Jiang R, The transcription factors Foxf1 and Foxf2 integrate the SHH, HGF and TGFbeta signaling pathways to drive tongue organogenesis. Development. 2022 Nov 1;149(21):dev200667 |
2 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
1* | J:214315 Yamada M, Clark J, Iulianella A, MLLT11/AF1q is differentially expressed in maturing neurons during development. Gene Expr Patterns. 2014 Jul;15(2):80-7 |
1* | J:146829 Yamada W, Nagao K, Horikoshi K, Fujikura A, Ikeda E, Inagaki Y, Kakitani M, Tomizuka K, Miyazaki H, Suda T, Takubo K, Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun. 2009 Apr 10;381(3):453-8 |
1 | J:218980 Yan J, Zhang L, Xu J, Sultana N, Hu J, Cai X, Li J, Xu PX, Cai CL, Smad4 regulates ureteral smooth muscle cell differentiation during mouse embryogenesis. PLoS One. 2014;9(8):e104503 |
1 | J:311873 Ye S, Yang N, Lu T, Wu T, Wang L, Pan YH, Cao X, Yuan X, Wisniewski T, Dang S, Zhang W, Adamts18 modulates the development of the aortic arch and common carotid artery. iScience. 2021 Jun 25;24(6):102672 |
1 | J:296772 Yin W, Kim HT, Wang S, Gunawan F, Li R, Buettner C, Grohmann B, Sengle G, Sinner D, Offermanns S, Stainier DYR, Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis. Eur Respir J. 2019 Mar;53(3) |
1 | J:266389 Yin W, Kim HT, Wang S, Gunawan F, Wang L, Kishimoto K, Zhong H, Roman D, Preussner J, Guenther S, Graef V, Buettner C, Grohmann B, Looso M, Morimoto M, Mardon G, Offermanns S, Stainier DYR, The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis. Nat Commun. 2018 Jul 19;9(1):2815 |
1* | J:79481 Yu J, Carroll TJ, McMahon AP, Sonic hedgehog regulates proliferation and differentiation of mesenchymal cells in the mouse metanephric kidney. Development. 2002 Nov;129(22):5301-12 |
1 | J:157920 Zovein AC, Luque A, Turlo KA, Hofmann JJ, Yee KM, Becker MS, Fassler R, Mellman I, Lane TF, Iruela-Arispe ML, Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism. Dev Cell. 2010 Jan 19;18(1):39-51 |
Actb actin, beta (Synonyms: Actx, A-X actin-like protein, beta-actin, E430023M04Rik) | |
Results | Reference |
1 | J:213791 Dutta DJ, Zameer A, Mariani JN, Zhang J, Asp L, Huynh J, Mahase S, Laitman BM, Argaw AT, Mitiku N, Urbanski M, Melendez-Vasquez CV, Casaccia P, Hayot F, Bottinger EP, Brown CW, John GR, Combinatorial actions of Tgfbeta and Activin ligands promote oligodendrocyte development and CNS myelination. Development. 2014 Jun;141(12):2414-28 |
1* | J:243480 Gomez-Herreros F, Schuurs-Hoeijmakers JH, McCormack M, Greally MT, Rulten S, Romero-Granados R, Counihan TJ, Chaila E, Conroy J, Ennis S, Delanty N, Cortes-Ledesma F, de Brouwer AP, Cavalleri GL, El-Khamisy SF, de Vries BB, Caldecott KW, TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function. Nat Genet. 2014 May;46(5):516-21 |
1 | J:190424 Kraemer N, Neubert G, Issa L, Ninnemann O, Seiler AE, Kaindl AM, Reference genes in the developing murine brain and in differentiating embryonic stem cells. Neurol Res. 2012 Sep;34(7):664-8 |
2 | J:330439 Liu H, He L, Cheng Q, Luo W, Zhao T, Yang D, Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states. Int J Mol Med. 2022 Nov;50(5) |
1 | J:316972 Mehta A, Dobersch S, Dammann RH, Bellusci S, Ilinskaya ON, Braun T, Barreto G, Validation of Tuba1a as appropriate internal control for normalization of gene expression analysis during mouse lung development. Int J Mol Sci. 2015 Feb 25;16(3):4492-511 |
Actc1 actin, alpha, cardiac muscle 1 (Synonyms: Actc-1, alphac-actin) | |
Results | Reference |
1* | J:174611 Azhar M, Brown K, Gard C, Chen H, Rajan S, Elliott DA, Stevens MV, Camenisch TD, Conway SJ, Doetschman T, Transforming growth factor Beta2 is required for valve remodeling during heart development. Dev Dyn. 2011 Sep;240(9):2127-41 |
1 | J:320322 Chen WC, Zhang Y, Ma D, Ma XJ, Shou WN, Huang GY, Bmp2 regulates the interaction between EPDCs and myocytes in cardiac OFT. Med Hypotheses. 2012 Aug;79(2):174-7 |
1* | J:16888 Mason IJ, Fuller-Pace F, Smith R, Dickson C, FGF-7 (keratinocyte growth factor) expression during mouse development suggests roles in myogenesis, forebrain regionalisation and epithelial-mesenchymal interactions. Mech Dev. 1994 Jan;45(1):15-30 |
Actg1 actin, gamma, cytoplasmic 1 (Synonyms: Actl, E51) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:330439 Liu H, He L, Cheng Q, Luo W, Zhao T, Yang D, Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states. Int J Mol Med. 2022 Nov;50(5) |
Actg2 actin, gamma 2, smooth muscle, enteric (Synonyms: Act-4, Act4, Acta3, SMGA) | |
Results | Reference |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1 | J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Actl6a actin-like 6A (Synonyms: 2810432C06Rik, Actl6, ARP4, Baf53a) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
Actl6b actin-like 6B (Synonyms: Actl6, ArpNa, Baf53b) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
1* | J:281311 Nakano Y, Wiechert S, Banfi B, Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8 |
1 | J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12) |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
Actn1 actinin, alpha 1 (Synonyms: 3110023F10Rik) | |
Results | Reference |
1 | J:213298 Chen J, Huang ZP, Seok HY, Ding J, Kataoka M, Zhang Z, Hu X, Wang G, Lin Z, Wang S, Pu WT, Liao R, Wang DZ, mir-17-92 cluster is required for and sufficient to induce cardiomyocyte proliferation in postnatal and adult hearts. Circ Res. 2013 Jun 7;112(12):1557-66 |
Actn2 actinin alpha 2 (Synonyms: 1110008F24Rik) | |
Results | Reference |
1 | J:332132 Cattaneo P, Hayes MGB, Baumgarten N, Hecker D, Peruzzo S, Aslan GS, Kunderfranco P, Larcher V, Zhang L, Contu R, Fonseca G, Spinozzi S, Chen J, Condorelli G, Dimmeler S, Schulz MH, Heinz S, Guimaraes-Camboa N, Evans SM, DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal. Nat Commun. 2022 Dec 2;13(1):7444 |
1 | J:236425 Clay H, Wilsbacher LD, Wilson SJ, Duong DN, McDonald M, Lam I, Park KE, Chun J, Coughlin SR, Sphingosine 1-phosphate receptor-1 in cardiomyocytes is required for normal cardiac development. Dev Biol. 2016 Oct 1;418(1):157-65 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
2 | J:104324 Hirschy A, Schatzmann F, Ehler E, Perriard JC, Establishment of cardiac cytoarchitecture in the developing mouse heart. Dev Biol. 2006 Jan 15;289(2):430-41 |
1 | J:224310 Ishihara T, Ban-Ishihara R, Maeda M, Matsunaga Y, Ichimura A, Kyogoku S, Aoki H, Katada S, Nakada K, Nomura M, Mizushima N, Mihara K, Ishihara N, Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development. Mol Cell Biol. 2015 Jan;35(1):211-23 |
1 | J:97478 Lu S, Borst DE, Horowits R, N-RAP expression during mouse heart development. Dev Dyn. 2005 May;233(1):201-12 |
1 | J:70373 Mills M, Yang N, Weinberger R, Vander Woude DL, Beggs AH, Easteal S, North K, Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy. Hum Mol Genet. 2001 Jun 15;10(13):1335-46 |
1 | J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Actn3 actinin alpha 3 | |
Results | Reference |
1 | J:70373 Mills M, Yang N, Weinberger R, Vander Woude DL, Beggs AH, Easteal S, North K, Differential expression of the actin-binding proteins, alpha-actinin-2 and -3, in different species: implications for the evolution of functional redundancy. Hum Mol Genet. 2001 Jun 15;10(13):1335-46 |
1 | J:178379 Richard AF, Demignon J, Sakakibara I, Pujol J, Favier M, Strochlic L, Le Grand F, Sgarioto N, Guernec A, Schmitt A, Cagnard N, Huang R, Legay C, Guillet-Deniau I, Maire P, Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression. Dev Biol. 2011 Nov 15;359(2):303-20 |
Actr3 ARP3 actin-related protein 3 (Synonyms: 1200003A09Rik, Arp3) | |
Results | Reference |
1 | J:235720 Wang PS, Chou FS, Ramachandran S, Xia S, Chen HY, Guo F, Suraneni P, Maher BJ, Li R, Crucial roles of the Arp2/3 complex during mammalian corticogenesis. Development. 2016 Aug 1;143(15):2741-52 |
Acvr1 activin A receptor, type 1 (Synonyms: ActR-I, ActRIA, Acvr, Acvr1a, Acvrlk2, Alk-2, ALK2, Alk8, D330013D15Rik, SKR1, Tsk7L) | |
Results | Reference |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
Acvr1b activin A receptor, type 1B (Synonyms: ActR-IB, ActRIB, Acvrlk4, Alk4, SKR2) | |
Results | Reference |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
Acvr2a activin receptor IIA (Synonyms: ActRIIa, Acvr2, tActRII) | |
Results | Reference |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
Acvr2b activin receptor IIB (Synonyms: ActRIIB) | |
Results | Reference |
1 | J:151466 Gamer LW, Cox K, Carlo JM, Rosen V, Overexpression of BMP3 in the developing skeleton alters endochondral bone formation resulting in spontaneous rib fractures. Dev Dyn. 2009 Aug 3;238(9):2374-2381 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
Acvrl1 activin A receptor, type II-like 1 (Synonyms: activin receptor-like kinase-1, Acvrlk1, Alk-1, Alk1) | |
Results | Reference |
1 | J:308817 Fu Y, Wang H, Dai H, Zhu Q, Cui CP, Sun X, Li Y, Deng Z, Zhou X, Ge Y, Peng Z, Yuan C, Wu B, Yang X, Li R, Liu CH, He F, Wei W, Zhang L, OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin. Mol Cell. 2021 Aug 5;81(15):3187-3204.e7 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
2 | J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521 |
Adam9 ADAM metallopeptidase domain 9 (Synonyms: MDC9, MDC9, mKIAA0021, Mltng, Mltng) | |
Results | Reference |
1* | J:97065 Asayesh A, Alanentalo T, Khoo NK, Ahlgren U, Developmental expression of metalloproteases ADAM 9, 10, and 17 becomes restricted to divergent pancreatic compartments. Dev Dyn. 2005 Apr;232(4):1105-14 |
Adam10 a disintegrin and metallopeptidase domain 10 (Synonyms: 1700031C13Rik, kuz, kuzbanian) | |
Results | Reference |
1* | J:97065 Asayesh A, Alanentalo T, Khoo NK, Ahlgren U, Developmental expression of metalloproteases ADAM 9, 10, and 17 becomes restricted to divergent pancreatic compartments. Dev Dyn. 2005 Apr;232(4):1105-14 |
1* | J:336871 Toonen JA, Ronchetti A, Sidjanin DJ, A Disintegrin and Metalloproteinase10 (ADAM10) Regulates NOTCH Signaling during Early Retinal Development. PLoS One. 2016;11(5):e0156184 |
1* | J:149783 Tousseyn T, Thathiah A, Jorissen E, Raemaekers T, Konietzko U, Reiss K, Maes E, Snellinx A, Serneels L, Nyabi O, Annaert W, Saftig P, Hartmann D, De Strooper B, ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase. J Biol Chem. 2009 Apr 24;284(17):11738-47 |
Adam11 a disintegrin and metallopeptidase domain 11 (Synonyms: Mdc) | |
Results | Reference |
1* | J:80252 Rybnikova E, Karkkainen I, Pelto-Huikko M, Huovila AP, Developmental regulation and neuronal expression of the cellular disintegrin ADAM11 gene in mouse nervous system. Neuroscience. 2002;112(4):921-34 |
Adam12 ADAM metallopeptidase domain 12 (Synonyms: ADAM12, Mltna) | |
Results | Reference |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1* | J:48131 Kurisaki T, Masuda A, Osumi N, Nabeshima Y, Fujisawa-Sehara A, Spatially- and temporally-restricted expression of meltrin alpha (ADAM12) and beta (ADAM19) in mouse embryo. Mech Dev. 1998 May;73(2):211-5 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
Adam17 a disintegrin and metallopeptidase domain 17 (Synonyms: CD156b, Tace) | |
Results | Reference |
1* | J:97065 Asayesh A, Alanentalo T, Khoo NK, Ahlgren U, Developmental expression of metalloproteases ADAM 9, 10, and 17 becomes restricted to divergent pancreatic compartments. Dev Dyn. 2005 Apr;232(4):1105-14 |
1 | J:214578 Hassemer EL, Endres B, Toonen JA, Ronchetti A, Dubielzig R, Sidjanin DJ, ADAM17 transactivates EGFR signaling during embryonic eyelid closure. Invest Ophthalmol Vis Sci. 2013 Jan;54(1):132-40 |
2* | J:203202 Li Q, Zhang Z, Li Z, Zhou M, Liu B, Pan L, Ma Z, Zheng Y, ADAM17 is critical for multipolar exit and radial migration of neuronal intermediate progenitor cells in mice cerebral cortex. PLoS One. 2013;8(6):e65703 |
2* | J:85547 Shi W, Chen H, Sun J, Buckley S, Zhao J, Anderson KD, Williams RG, Warburton D, TACE is required for fetal murine cardiac development and modeling. Dev Biol. 2003 Sep 15;261(2):371-80 |
1 | J:124878 Sierro F, Biben C, Martinez-Munoz L, Mellado M, Ransohoff RM, Li M, Woehl B, Leung H, Groom J, Batten M, Harvey RP, Martinez-A C, Mackay CR, Mackay F, Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14759-64 |
1* | J:336871 Toonen JA, Ronchetti A, Sidjanin DJ, A Disintegrin and Metalloproteinase10 (ADAM10) Regulates NOTCH Signaling during Early Retinal Development. PLoS One. 2016;11(5):e0156184 |
1 | J:227692 van Erp S, van den Heuvel DM, Fujita Y, Robinson RA, Hellemons AJ, Adolfs Y, Van Battum EY, Blokhuis AM, Kuijpers M, Demmers JA, Hedman H, Hoogenraad CC, Siebold C, Yamashita T, Pasterkamp RJ, Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases. Dev Cell. 2015 Dec 7;35(5):537-52 |
1* | J:195050 Wilson CL, Gough PJ, Chang CA, Chan CK, Frey JM, Liu Y, Braun KR, Chin MT, Wight TN, Raines EW, Endothelial deletion of ADAM17 in mice results in defective remodeling of the semilunar valves and cardiac dysfunction in adults. Mech Dev. 2013 Apr-May;130(4-5):272-89 |
1* | J:68672 Zhao J, Chen H, Peschon JJ, Shi W, Zhang Y, Frank SJ, Warburton D, Pulmonary hypoplasia in mice lacking tumor necrosis factor-alpha converting enzyme indicates an indispensable role for cell surface protein shedding during embryonic lung branching morphogenesis. Dev Biol. 2001 Apr 1;232(1):204-18 |
Adam19 ADAM metallopeptidase domain 19 (Synonyms: Mltnb) | |
Results | Reference |
1 | J:284333 Arai HN, Sato F, Yamamoto T, Woltjen K, Kiyonari H, Yoshimoto Y, Shukunami C, Akiyama H, Kist R, Sehara-Fujisawa A, Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate. Cell Rep. 2019 Oct 15;29(3):603-616.e5 |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1* | J:113299 Bu SM, Yang YJ, Miao CL, Li HJ, Newcomer RG, Sang QX, Duan EK, Developmental and hormonal regulation of meltrin beta (ADAM19) expression in mouse testes during embryonic and postnatal life. Life Sci. 2006 Oct 26;79(22):2112-8 |
1* | J:48131 Kurisaki T, Masuda A, Osumi N, Nabeshima Y, Fujisawa-Sehara A, Spatially- and temporally-restricted expression of meltrin alpha (ADAM12) and beta (ADAM19) in mouse embryo. Mech Dev. 1998 May;73(2):211-5 |
1 | J:144429 Yumoto N, Wakatsuki S, Kurisaki T, Hara Y, Osumi N, Frisen J, Sehara-Fujisawa A, Meltrin beta/ADAM19 interacting with EphA4 in developing neural cells participates in formation of the neuromuscular junction. PLoS One. 2008;3(10):e3322 |
1 | J:87592 Zhou HM, Weskamp G, Chesneau V, Sahin U, Vortkamp A, Horiuchi K, Chiusaroli R, Hahn R, Wilkes D, Fisher P, Baron R, Manova K, Basson CT, Hempstead B, Blobel CP, Essential role for ADAM19 in cardiovascular morphogenesis. Mol Cell Biol. 2004 Jan;24(1):96-104 |
Adamts1 ADAM metallopeptidase with thrombospondin type 1 motif 1 (Synonyms: ADAM-TS1, ADAMTS-1, METH-1, METH1) | |
Results | Reference |
1 | J:179734 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS, Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Dev Dyn. 2012 Feb;241(2):303-14 |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
2* | J:119223 Kern CB, Twal WO, Mjaatvedt CH, Fairey SE, Toole BP, Iruela-Arispe ML, Argraves WS, Proteolytic cleavage of versican during cardiac cushion morphogenesis. Dev Dyn. 2006 Aug;235(8):2238-47 |
1* | J:102464 Lee NV, Rodriguez-Manzaneque JC, Thai SN, Twal WO, Luque A, Lyons KM, Argraves WS, Iruela-Arispe ML, Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1. J Biol Chem. 2005 Oct 14;280(41):34796-804 |
3 | J:348792 Mead TJ, Bhutada S, Foulcer SJ, Peruzzi N, Nelson CM, Seifert DE, Larkin J, Tran-Lundmark K, Filmus J, Apte SS, Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development. Matrix Biol. 2024 May 13; |
Adamts2 ADAM metallopeptidase with thrombospondin type 1 motif 2 (Synonyms: ADAM-TS2, a disintegrin and metalloproteinase with thrombospondin repeats, hPCPNI, procollagen N-proteinase) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Adamts3 ADAM metallopeptidase with thrombospondin type 1 motif 3 (Synonyms: 1100001H14Rik, 6330442E02Rik) | |
Results | Reference |
1 | J:240398 Ogino H, Hisanaga A, Kohno T, Kondo Y, Okumura K, Kamei T, Sato T, Asahara H, Tsuiji H, Fukata M, Hattori M, Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin. J Neurosci. 2017 Mar 22;37(12):3181-3191 |
1 | J:281878 Yook C, Kim K, Kim D, Kang H, Kim SG, Kim E, Kim SY, A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice. Front Mol Neurosci. 2019;12:241 |
Adamts4 ADAM metallopeptidase with thrombospondin type 1 motif 4 (Synonyms: ADAM-TS4, aggrecanase-1) | |
Results | Reference |
1 | J:196913 Bertrand J, Stange R, Hidding H, Echtermeyer F, Nalesso G, Godmann L, Timmen M, Bruckner P, Dell'Accio F, Raschke MJ, Pap T, Dreier R, Syndecan 4 supports bone fracture repair, but not fetal skeletal development, in mice. Arthritis Rheum. 2013 Mar;65(3):743-52 |
1* | J:119223 Kern CB, Twal WO, Mjaatvedt CH, Fairey SE, Toole BP, Iruela-Arispe ML, Argraves WS, Proteolytic cleavage of versican during cardiac cushion morphogenesis. Dev Dyn. 2006 Aug;235(8):2238-47 |
Adamts5 ADAM metallopeptidase with thrombospondin type 1 motif 5 (Synonyms: 9530092O11Rik, ADAM-TS5) | |
Results | Reference |
1 | J:179734 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS, Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Dev Dyn. 2012 Feb;241(2):303-14 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1* | J:148803 McCulloch DR, Le Goff C, Bhatt S, Dixon LJ, Sandy JD, Apte SS, Adamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues. Gene Expr Patterns. 2009 Jun;9(5):314-23 |
2 | J:348792 Mead TJ, Bhutada S, Foulcer SJ, Peruzzi N, Nelson CM, Seifert DE, Larkin J, Tran-Lundmark K, Filmus J, Apte SS, Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development. Matrix Biol. 2024 May 13; |
Adamts6 ADAM metallopeptidase with thrombospondin type 1 motif 6 (Synonyms: A930019D11Rik, ADAM-TS6, b2b1879.1Clo, b2b2029Clo, b2b2182Clo, b2b2187.1Clo, b2b2228Clo) | |
Results | Reference |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
Adamts9 ADAM metallopeptidase with thrombospondin type 1 motif 9 (Synonyms: 1810011L16Rik, 8430403M15Rik, E030027K14Rik, Gsfund3, Mhdaund3, Mhdaund4, UND3, UND4) | |
Results | Reference |
1 | J:179734 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS, Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Dev Dyn. 2012 Feb;241(2):303-14 |
1* | J:119223 Kern CB, Twal WO, Mjaatvedt CH, Fairey SE, Toole BP, Iruela-Arispe ML, Argraves WS, Proteolytic cleavage of versican during cardiac cushion morphogenesis. Dev Dyn. 2006 Aug;235(8):2238-47 |
Adamts10 ADAM metallopeptidase with thrombospondin type 1 motif 10 (Synonyms: ZnMP) | |
Results | Reference |
1* | J:275665 Wang LW, Kutz WE, Mead TJ, Beene LC, Singh S, Jenkins MW, Reinhardt DP, Apte SS, Adamts10 inactivation in mice leads to persistence of ocular microfibrils subsequent to reduced fibrillin-2 cleavage. Matrix Biol. 2019 Apr;77:117-128 |
Adamts16 ADAM metallopeptidase with thrombospondin type 1 motif 16 (Synonyms: MGC:37086) | |
Results | Reference |
1 | J:353576 Lin Y, Yang Q, Lin X, Liu X, Qian Y, Xu D, Cao N, Han X, Zhu Y, Hu W, He X, Yu Z, Kong X, Zhu L, Zhong Z, Liu K, Zhou B, Wang Y, Peng J, Zhu W, Wang J, Extracellular Matrix Disorganization Caused by ADAMTS16 Deficiency Leads to Bicuspid Aortic Valve With Raphe Formation. Circulation. 2024 Feb 20;149(8):605-626 |
1 | J:361964 Wang M, Liu H, Zhang M, Niu X, Sun M, Wang F, Ni Y, Hong T, Zhang W, Dang S, The secreted protease ADAMTS18 links early isoform transformation and maturation of glomerular basement membrane macromolecules to the integrity of the glomerular filtration barrier. Biochem Biophys Res Commun. 2025 Mar 1;750:151386 |
Adamts17 ADAM metallopeptidase with thrombospondin type 1 motif 17 (Synonyms: AU023434) | |
Results | Reference |
1 | J:295274 Oichi T, Taniguchi Y, Soma K, Oshima Y, Yano F, Mori Y, Chijimatsu R, Kim-Kaneyama JR, Tanaka S, Saito T, Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway. Cell Mol Life Sci. 2019 Dec;76(23):4795-4809 |
Adamts18 ADAM metallopeptidase with thrombospondin type 1 motif 18 (Synonyms: E130314N14Rik) | |
Results | Reference |
1 | J:352032 Wang L, He L, Yi W, Wang M, Xu F, Liu H, Nie J, Pan YH, Dang S, Zhang W, ADAMTS18-fibronectin interaction regulates the morphology of liver sinusoidal endothelial cells. iScience. 2024 Jul 19;27(7):110273 |
1* | J:321805 Wang L, Sun M, Zhang Q, Dang S, Zhang W, ADAMTS18 regulates early branching morphogenesis of lacrimal gland and has a significant association with the risk of dry eye in mice. Exp Eye Res. 2022 Feb 28;218:109020 |
1 | J:361964 Wang M, Liu H, Zhang M, Niu X, Sun M, Wang F, Ni Y, Hong T, Zhang W, Dang S, The secreted protease ADAMTS18 links early isoform transformation and maturation of glomerular basement membrane macromolecules to the integrity of the glomerular filtration barrier. Biochem Biophys Res Commun. 2025 Mar 1;750:151386 |
1 | J:321251 Yang N, Zhang Q, Ye S, Lu T, Sun M, Wang L, Wang M, Pan YH, Dang S, Zhang W, Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice. J Dent Res. 2022 Feb;101(2):226-234 |
1 | J:311873 Ye S, Yang N, Lu T, Wu T, Wang L, Pan YH, Cao X, Yuan X, Wisniewski T, Dang S, Zhang W, Adamts18 modulates the development of the aortic arch and common carotid artery. iScience. 2021 Jun 25;24(6):102672 |
Adamtsl2 ADAMTS-like 2 (Synonyms: A930008K15Rik) | |
Results | Reference |
1* | J:124013 Koo BH, Goff CL, Jungers KA, Vasanji A, O'flaherty J, Weyman CM, Apte SS, ADAMTS-like 2 (ADAMTSL2) is a secreted glycoprotein that is widely expressed during mouse embryogenesis and is regulated during skeletal myogenesis. Matrix Biol. 2007 Jul;26(6):431-41 |
Adamtsl4 ADAMTS-like 4 (Synonyms: Tsrc1) | |
Results | Reference |
1* | J:226844 Collin GB, Hubmacher D, Charette JR, Hicks WL, Stone L, Yu M, Naggert JK, Krebs MP, Peachey NS, Apte SS, Nishina PM, Disruption of murine Adamtsl4 results in zonular fiber detachment from the lens and in retinal pigment epithelium dedifferentiation. Hum Mol Genet. 2015 Dec 15;24(24):6958-74 |
Adamtsl5 ADAMTS-like 5 (Synonyms: 2010109H09Rik, Thsd6) | |
Results | Reference |
2* | J:192744 Bader HL, Wang LW, Ho JC, Tran T, Holden P, Fitzgerald J, Atit RP, Reinhardt DP, Apte SS, A disintegrin-like and metalloprotease domain containing thrombospondin type 1 motif-like 5 (ADAMTSL5) is a novel fibrillin-1-, fibrillin-2-, and heparin-binding member of the ADAMTS superfamily containing a netrin-like module. Matrix Biol. 2012 Sep-Oct;31(7-8):398-411 |
Adcy2 adenylate cyclase 2 (Synonyms: mKIAA1060) | |
Results | Reference |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
Adcy3 adenylate cyclase 3 (Synonyms: AC3, ACIII, mKIAA0511) | |
Results | Reference |
1 | J:102255 Balmer CW, LaMantia AS, Noses and neurons: induction, morphogenesis, and neuronal differentiation in the peripheral olfactory pathway. Dev Dyn. 2005 Nov;234(3):464-81 |
1 | J:109287 Balmer CW, LaMantia AS, Loss of Gli3 and Shh function disrupts olfactory axon trajectories. J Comp Neurol. 2004 May 3;472(3):292-307 |
1 | J:166772 DeRouen MC, Zhen H, Tan SH, Williams S, Marinkovich MP, Oro AE, Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation. BMC Dev Biol. 2010;10:112 |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
1 | J:237697 Maurya DK, Henriques T, Marini M, Pedemonte N, Galietta LJ, Rock JR, Harfe BD, Menini A, Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice. PLoS One. 2015;10(6):e0129171 |
1 | J:206876 Song JY, Park R, Kim JY, Hughes L, Lu L, Kim S, Johnson RL, Cho SH, Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev Biol. 2014 Feb 15;386(2):281-90 |
1 | J:213914 Tong CK, Han YG, Shah JK, Obernier K, Guinto CD, Alvarez-Buylla A, Primary cilia are required in a unique subpopulation of neural progenitors. Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12438-43 |
1 | J:163859 Tucker ES, Lehtinen MK, Maynard T, Zirlinger M, Dulac C, Rawson N, Pevny L, Lamantia AS, Proliferative and transcriptional identity of distinct classes of neural precursors in the mammalian olfactory epithelium. Development. 2010 Aug 1;137(15):2471-81 |
Adcy6 adenylate cyclase 6 (Synonyms: AC6) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Adcy7 adenylate cyclase 7 | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
Adcyap1 adenylate cyclase activating polypeptide 1 (Synonyms: PACAP) | |
Results | Reference |
1 | J:238369 Mihalas AB, Elsen GE, Bedogni F, Daza RA, Ramos-Laguna KA, Arnold SJ, Hevner RF, Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity. Cell Rep. 2016 Jun 28;16(1):92-105 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Adcyap1r1 adenylate cyclase activating polypeptide 1 receptor 1 (Synonyms: 2900024I10Rik, PAC1, PAC1R, PACAP1-R) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:36388 Sheward WJ, Lutz EM, Harmar AJ, Expression of pituitary adenylate cyclase activating polypeptide receptors in the early mouse embryo as assessed by reverse transcription polymerase chain reaction and in situ hybridisation. Neurosci Lett. 1996 Sep 20;216(1):45-8 |
Add1 adducin 1 | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Adgb androglobin (Synonyms: 9130014G24Rik) | |
Results | Reference |
1 | J:326350 Keppner A, Correia M, Santambrogio S, Koay TW, Maric D, Osterhof C, Winter DV, Clerc A, Stumpe M, Chalmel F, Dewilde S, Odermatt A, Kressler D, Hankeln T, Wenger RH, Hoogewijs D, Androglobin, a chimeric mammalian globin, is required for male fertility. Elife. 2022 Jun 14;11:e72374 |
Adgre1 adhesion G protein-coupled receptor E1 (Synonyms: DD7A5-7, EGF-TM7, Emr1, F4/80, Ly71, TM7LN3) | |
Results | Reference |
1 | J:346910 Ayyangar U, Karkhanis A, Tay H, Afandi AFB, Bhattacharjee O, Ks L, Lee SH, Chan J, Raghavan S, Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin. EMBO J. 2024 Apr;43(7):1113-1134 |
1* | J:264675 Fransen MF, Benonisson H, van Maren WW, Sow HS, Breukel C, Linssen MM, Claassens JWC, Brouwers C, van der Kaa J, Camps M, Kleinovink JW, Vonk KK, van Heiningen S, Klar N, van Beek L, van Harmelen V, Daxinger L, Nandakumar KS, Holmdahl R, Coward C, Lin Q, Hirose S, Salvatori D, van Hall T, van Kooten C, Mastroeni P, Ossendorp F, Verbeek JS, A Restricted Role for FcgammaR in the Regulation of Adaptive Immunity. J Immunol. 2018 Apr 15;200(8):2615-2626 |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1 | J:334094 Gu X, Heinrich A, Li SY, DeFalco T, Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions. Nat Commun. 2023 Mar 15;14(1):1439 |
1 | J:189052 Hoeffel G, Wang Y, Greter M, See P, Teo P, Malleret B, Leboeuf M, Low D, Oller G, Almeida F, Choy SH, Grisotto M, Renia L, Conway SJ, Stanley ER, Chan JK, Ng LG, Samokhvalov IM, Merad M, Ginhoux F, Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages. J Exp Med. 2012 Jun 4;209(6):1167-81 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1* | J:122404 Kim KE, Sung HK, Koh GY, Lymphatic development in mouse small intestine. Dev Dyn. 2007 Jul;236(7):2020-5 |
1 | J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47 |
1 | J:340406 Lai Y, Guo Y, Liao C, Mao C, Liu J, Ren C, Yang W, Luo L, Chen W, Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development. Sci Rep. 2023 Sep 13;13(1):15170 |
1* | J:346378 Liang Y, Hu Y, Zhang J, Song H, Zhang X, Chen Y, Peng Y, Sun L, Sun Y, Xue R, Ji S, Li C, Rong Z, Yang B, Xu Y, Dynamic pathological analysis reveals a protective role against skin fibrosis for TREM2-dependent macrophages. Theranostics. 2024;14(5):2232-2245 |
1 | J:339241 Liu, K., Intercellular genetic tracing of cardiac endothelium in the developing heart. Dev Cell. 2023 Aug 21;58(16):1502-1512 |
1* | J:278916 Maruyama K, Miyagawa-Tomita S, Mizukami K, Matsuzaki F, Kurihara H, Isl1-expressing non-venous cell lineage contributes to cardiac lymphatic vessel development. Dev Biol. 2019 Aug 15;452(2):134-143 |
1 | J:205283 Munoz-Espin D, Canamero M, Maraver A, Gomez-Lopez G, Contreras J, Murillo-Cuesta S, Rodriguez-Baeza A, Varela-Nieto I, Ruberte J, Collado M, Serrano M, Programmed cell senescence during mammalian embryonic development. Cell. 2013 Nov 21;155(5):1104-18 |
1 | J:275137 Munro DAD, Wineberg Y, Tarnick J, Vink CS, Li Z, Pridans C, Dzierzak E, Kalisky T, Hohenstein P, Davies JA, Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development. Elife. 2019 Feb 13;8:e43271 |
1 | J:239420 Rantakari P, Jappinen N, Lokka E, Mokkala E, Gerke H, Peuhu E, Ivaska J, Elima K, Auvinen K, Salmi M, Fetal liver endothelium regulates the seeding of tissue-resident macrophages. Nature. 2016 Oct 20;538(7625):392-396 |
1 | J:349014 Rinta-Jaskari MM, Naillat F, Ruotsalainen HJ, Ronkainen VP, Heljasvaara R, Akram SU, Izzi V, Miinalainen I, Vainio SJ, Pihlajaniemi TA, Collagen XVIII regulates extracellular matrix integrity in the developing nephrons and impacts nephron progenitor cell behavior. Matrix Biol. 2024 May 22; |
1 | J:325090 Sakashita H, Bando Y, Nagasaka A, Sakiyama K, Onozawa G, Taira F, Ogasawara Y, Owada Y, Sakashita H, Amano O, Spatial and chronological localization of septoclasts in the mouse Meckel's cartilage. Histochem Cell Biol. 2022 May;157(5):569-580 |
1 | J:182209 Schulz C, Gomez Perdiguero E, Chorro L, Szabo-Rogers H, Cagnard N, Kierdorf K, Prinz M, Wu B, Jacobsen SE, Pollard JW, Frampton J, Liu KJ, Geissmann F, A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science. 2012 Apr 6;336(6077):86-90 |
1* | J:293511 Suttorp CM, Cremers NA, van Rheden R, Regan RF, Helmich P, van Kempen S, Kuijpers-Jagtman AM, Wagener FADTG, Chemokine Signaling during Midline Epithelial Seam Disintegration Facilitates Palatal Fusion. Front Cell Dev Biol. 2017;5:94 |
1* | J:48210 Takahashi K, Donovan MJ, Rogers RA, Ezekowitz RA, Distribution of murine mannose receptor expression from early embryogenesis through to adulthood. Cell Tissue Res. 1998 May;292(2):311-23 |
1 | J:240148 Tan SY, Krasnow MA, Developmental origin of lung macrophage diversity. Development. 2016 Apr 15;143(8):1318-27 |
1 | J:326699 Tosun B, Wolff LI, Houben A, Nutt S, Hartmann C, Osteoclasts and Macrophages-Their Role in Bone Marrow Cavity Formation During Mouse Embryonic Development. J Bone Miner Res. 2022 Jun 11; |
1 | J:362739 Wu Y, Qin K, Xu Y, Rajhans S, Vo T, Lopez KM, Liu J, Nipper MH, Deng J, Yin X, Ramjit LR, Ye Z, Luan Y, Arda HE, Wang P, Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation. Elife. 2024 Jul 25;13 |
1* | J:203199 Yang CY, Chen JB, Tsai TF, Tsai YC, Tsai CY, Liang PH, Hsu TL, Wu CY, Netea MG, Wong CH, Hsieh SL, CLEC4F is an inducible C-type lectin in F4/80-positive cells and is involved in alpha-galactosylceramide presentation in liver. PLoS One. 2013;8(6):e65070 |
1* | J:171387 Zhang H, Tse J, Hu X, Witte M, Bernas M, Kang J, Tilahun F, Hong YK, Qiu M, Chen L, Novel discovery of LYVE-1 expression in the hyaloid vascular system. Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6157-61 |
Adgrf5 adhesion G protein-coupled receptor F5 (Synonyms: 8430401C09Rik, Gpr116) | |
Results | Reference |
1* | J:221769 Bridges JP, Ludwig MG, Mueller M, Kinzel B, Sato A, Xu Y, Whitsett JA, Ikegami M, Orphan G protein-coupled receptor GPR116 regulates pulmonary surfactant pool size. Am J Respir Cell Mol Biol. 2013 Sep;49(3):348-57 |
Adgrg1 adhesion G protein-coupled receptor G1 (Synonyms: Cyt28, Gpr56) | |
Results | Reference |
1* | J:166517 Chen G, Yang L, Begum S, Xu L, GPR56 is essential for testis development and male fertility in mice. Dev Dyn. 2010 Dec;239(12):3358-67 |
1* | J:137733 Iguchi T, Sakata K, Yoshizaki K, Tago K, Mizuno N, Itoh H, Orphan G protein-coupled receptor GPR56 regulates neural progenitor cell migration via a G alpha 12/13 and Rho pathway. J Biol Chem. 2008 May 23;283(21):14469-78 |
1 | J:136385 Li S, Jin Z, Koirala S, Bu L, Xu L, Hynes RO, Walsh CA, Corfas G, Piao X, GPR56 regulates pial basement membrane integrity and cortical lamination. J Neurosci. 2008 May 28;28(22):5817-26 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Adgrg3 adhesion G protein-coupled receptor G3 (Synonyms: A030001G24Rik, Gpr97, Pb99) | |
Results | Reference |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
Adgrg6 adhesion G protein-coupled receptor G6 (Synonyms: 1190004A11Rik, DREG, Gpr126, LOC215798) | |
Results | Reference |
2 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1* | J:202002 Patra C, van Amerongen MJ, Ghosh S, Ricciardi F, Sajjad A, Novoyatleva T, Mogha A, Monk KR, Muhlfeld C, Engel FB, Organ-specific function of adhesion G protein-coupled receptor GPR126 is domain-dependent. Proc Natl Acad Sci U S A. 2013 Oct 15;110(42):16898-903 |
Adgrl1 adhesion G protein-coupled receptor L1 (Synonyms: 2900070I05Rik, Lec2, lectomedin-2, Lphn1, mKIAA0821) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:348278 Liakath-Ali K, Refaee R, Sudhof TC, Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development. PLoS Biol. 2024 May;22(5):e3002599 |
Adgrl2 adhesion G protein-coupled receptor L2 (Synonyms: Lec1, Lphh1, Lphn2, mKIAA0786) | |
Results | Reference |
1 | J:348278 Liakath-Ali K, Refaee R, Sudhof TC, Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development. PLoS Biol. 2024 May;22(5):e3002599 |
Adgrl3 adhesion G protein-coupled receptor L3 (Synonyms: 5430402I23Rik, D130075K09Rik, LEC3, lectomedin 3, Lphn3, mKIAA0768) | |
Results | Reference |
1 | J:348278 Liakath-Ali K, Refaee R, Sudhof TC, Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development. PLoS Biol. 2024 May;22(5):e3002599 |
Adgrv1 adhesion G protein-coupled receptor V1 (Synonyms: Gpr98, Mass1, Mgr1, Neurepin, VLGR1) | |
Results | Reference |
1 | J:90899 McMillan DR, White PC, Loss of the transmembrane and cytoplasmic domains of the very large G-protein-coupled receptor-1 (VLGR1 or Mass1) causes audiogenic seizures in mice. Mol Cell Neurosci. 2004 Jun;26(2):322-9 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:95518 Yagi H, Takamura Y, Yoneda T, Konno D, Akagi Y, Yoshida K, Sato M, Vlgr1 knockout mice show audiogenic seizure susceptibility. J Neurochem. 2005 Jan;92(1):191-202 |
1 | J:123389 Yagi H, Tokano H, Maeda M, Takabayashi T, Nagano T, Kiyama H, Fujieda S, Kitamura K, Sato M, Vlgr1 is required for proper stereocilia maturation of cochlear hair cells. Genes Cells. 2007 Feb;12(2):235-50 |
Adh1 alcohol dehydrogenase 1 (class I) (Synonyms: Adh-1, Adh1-e, Adh-1e, Adh-1-t, Adh1-t, Adh-1t, Adh1tl, ADH-AA, class I alcohol dehydrogenase) | |
Results | Reference |
1* | J:36366 Ang HL, Deltour L, Zgombic-Knight M, Wagner MA, Duester G, Expression patterns of class I and class IV alcohol dehydrogenase genes in developing epithelia suggest a role for alcohol dehydrogenase in local retinoic acid synthesis. Alcohol Clin Exp Res. 1996 Sep;20(6):1050-64 |
2 | J:42020 Haselbeck RJ, Ang HL, Deltour L, Duester G, Retinoic acid and alcohol/retinol dehydrogenase in the mouse adrenal gland: a potential endocrine source of retinoic acid during development. Endocrinology. 1997 Jul;138(7):3035-41 |
1* | J:49267 Haselbeck RJ, Duester G, ADH1 and ADH4 alcohol/retinol dehydrogenases in the developing adrenal blastema provide evidence for embryonic retinoid endocrine function. Dev Dyn. 1998 Sep;213(1):114-20 |
1* | J:26933 Shean ML, Duester G, The role of alcohol dehydrogenase in retinoic acid homeostasis and fetal alcohol syndrome. Alcohol Alcohol Suppl. 1993;2:51-6 |
1 | J:17402 Vonesch JL, Nakshatri H, Philippe M, Chambon P, Dolle P, Stage and tissue-specific expression of the alcohol dehydrogenase 1 (Adh-1) gene during mouse development. Dev Dyn. 1994 Mar;199(3):199-213 |
Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide (Synonyms: Adh3, Adh-5, GSNOR, S-nitrosoglutathione reductase) | |
Results | Reference |
1* | J:36366 Ang HL, Deltour L, Zgombic-Knight M, Wagner MA, Duester G, Expression patterns of class I and class IV alcohol dehydrogenase genes in developing epithelia suggest a role for alcohol dehydrogenase in local retinoic acid synthesis. Alcohol Clin Exp Res. 1996 Sep;20(6):1050-64 |
Adh7 alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide (Synonyms: Adh-3, Adh3, Adh3-e, Adh-3e, Adh3-t, Adh-3t, Adh4, Adt-1, IV ADH) | |
Results | Reference |
1* | J:36366 Ang HL, Deltour L, Zgombic-Knight M, Wagner MA, Duester G, Expression patterns of class I and class IV alcohol dehydrogenase genes in developing epithelia suggest a role for alcohol dehydrogenase in local retinoic acid synthesis. Alcohol Clin Exp Res. 1996 Sep;20(6):1050-64 |
2 | J:42020 Haselbeck RJ, Ang HL, Deltour L, Duester G, Retinoic acid and alcohol/retinol dehydrogenase in the mouse adrenal gland: a potential endocrine source of retinoic acid during development. Endocrinology. 1997 Jul;138(7):3035-41 |
1* | J:49267 Haselbeck RJ, Duester G, ADH1 and ADH4 alcohol/retinol dehydrogenases in the developing adrenal blastema provide evidence for embryonic retinoid endocrine function. Dev Dyn. 1998 Sep;213(1):114-20 |
Adipoq adiponectin, C1Q and collagen domain containing (Synonyms: Acdc, Acrp30, Ad, adipo, adiponectin, apM1, APN, GBP28) | |
Results | Reference |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
5 | J:102703 Fujimoto N, Matsuo N, Sumiyoshi H, Yamaguchi K, Saikawa T, Yoshimatsu H, Yoshioka H, Adiponectin is expressed in the brown adipose tissue and surrounding immature tissues in mouse embryos. Biochim Biophys Acta. 2005 Oct 15;1731(1):1-12 |
Adipor1 adiponectin receptor 1 (Synonyms: 2810031L11Rik) | |
Results | Reference |
1 | J:102703 Fujimoto N, Matsuo N, Sumiyoshi H, Yamaguchi K, Saikawa T, Yoshimatsu H, Yoshioka H, Adiponectin is expressed in the brown adipose tissue and surrounding immature tissues in mouse embryos. Biochim Biophys Acta. 2005 Oct 15;1731(1):1-12 |
1 | J:346053 Zhang J, Ruiz M, Bergh PO, Henricsson M, Stojanovic N, Devkota R, Henn M, Bohlooly-Y M, Hernandez-Hernandez A, Alsheimer M, Boren J, Pilon M, Shibuya H, Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2. Nat Commun. 2024 Mar 14;15(1):2315 |
Adipor2 adiponectin receptor 2 (Synonyms: 1110001I14Rik, D6Ucla1e) | |
Results | Reference |
1 | J:102703 Fujimoto N, Matsuo N, Sumiyoshi H, Yamaguchi K, Saikawa T, Yoshimatsu H, Yoshioka H, Adiponectin is expressed in the brown adipose tissue and surrounding immature tissues in mouse embryos. Biochim Biophys Acta. 2005 Oct 15;1731(1):1-12 |
1 | J:346053 Zhang J, Ruiz M, Bergh PO, Henricsson M, Stojanovic N, Devkota R, Henn M, Bohlooly-Y M, Hernandez-Hernandez A, Alsheimer M, Boren J, Pilon M, Shibuya H, Regulation of meiotic telomere dynamics through membrane fluidity promoted by AdipoR2-ELOVL2. Nat Commun. 2024 Mar 14;15(1):2315 |
Adm adrenomedullin (Synonyms: AM) | |
Results | Reference |
1* | J:67044 Caron KM, Smithies O, Extreme hydrops fetalis and cardiovascular abnormalities in mice lacking a functional Adrenomedullin gene. Proc Natl Acad Sci U S A. 2001 Jan 16;98(2):615-9 |
2* | J:49900 Montuenga LM, Mariano JM, Prentice MA, Cuttitta F, Jakowlew SB, Coordinate expression of transforming growth factor-beta1 and adrenomedullin in rodent embryogenesis. Endocrinology. 1998 Sep;139(9):3946-57 |
1 | J:39741 Montuenga LM, Martinez A, Miller MJ, Unsworth EJ, Cuttitta F, Expression of adrenomedullin and its receptor during embryogenesis suggests autocrine or paracrine modes of action. Endocrinology. 1997 Jan;138(1):440-51 |
1 | J:124878 Sierro F, Biben C, Martinez-Munoz L, Mellado M, Ransohoff RM, Li M, Woehl B, Leung H, Groom J, Batten M, Harvey RP, Martinez-A C, Mackay CR, Mackay F, Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14759-64 |
1* | J:51098 Yotsumoto S, Shimada T, Cui CY, Nakashima H, Fujiwara H, Ko MS, Expression of adrenomedullin, a hypotensive peptide, in the trophoblast giant cells at the embryo implantation site in mouse. Dev Biol. 1998 Nov 15;203(2):264-75 |
Adnp activity-dependent neuroprotective protein (Synonyms: mKIAA0784) | |
Results | Reference |
2* | J:85093 Pinhasov A, Mandel S, Torchinsky A, Giladi E, Pittel Z, Goldsweig AM, Servoss SJ, Brenneman DE, Gozes I, Activity-dependent neuroprotective protein: a novel gene essential for brain formation. Brain Res Dev Brain Res. 2003 Aug 12;144(1):83-90 |
1 | J:81041 Poggi SH, Vink J, Goodwin K, Hill JM, Brenneman DE, Pinhasov A, Gozes I, Spong CY, Differential expression of embryonic and maternal activity-dependent neuroprotective protein during mouse development. Am J Obstet Gynecol. 2002 Oct;187(4):973-6 |
Adnp2 ADNP homeobox 2 (Synonyms: 8430420L05Rik, MGC:38953, mKIAA0863, Zfp508) | |
Results | Reference |
1* | J:135357 Kushnir M, Dresner E, Mandel S, Gozes I, Silencing of the ADNP-family member, ADNP2, results in changes in cellular viability under oxidative stress. J Neurochem. 2008 Apr;105(2):537-45 |
Adora2a adenosine A2a receptor (Synonyms: A2AAR, A2aR, A2a, Rs, AA2AR, ARA2A) | |
Results | Reference |
1 | J:256526 Kuerbitz J, Arnett M, Ehrman S, Williams MT, Vorhees CV, Fisher SE, Garratt AN, Muglia LJ, Waclaw RR, Campbell K, Loss of Intercalated Cells (ITCs) in the Mouse Amygdala of Tshz1 Mutants Correlates with Fear, Depression, and Social Interaction Phenotypes. J Neurosci. 2018 Jan 31;38(5):1160-1177 |
1 | J:361228 Li Z, Shang Z, Sun M, Jiang X, Tian Y, Yang L, Wang Z, Su Z, Liu G, Li X, You Y, Yang Z, Xu Z, Zhang Z, Transcription factor Sp9 is a negative regulator of D1-type MSN development. Cell Death Discov. 2022 Jun 30;8(1):301 |
1 | J:350099 Song X, Chen H, Shang Z, Du H, Li Z, Wen Y, Liu G, Qi D, You Y, Yang Z, Zhang Z, Xu Z, Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons. Neurosci Bull. 2021 Jul;37(7):985-998 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
2 | J:238868 Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z, The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 2016 Aug 02;16(5):1431-44 |
Adra1b adrenergic receptor, alpha 1b (Synonyms: alpha1B-adrenergic receptor) | |
Results | Reference |
1* | J:43805 Abe-Dohmae S, Takagi Y, Harada N, Autonomous expression of aromatase during development of mouse brain is modulated by neurotransmitters. J Steroid Biochem Mol Biol. 1997 Apr;61(3-6):299-306 |
Adra1d adrenergic receptor, alpha 1d (Synonyms: Adra-1, Adra1, Adra1a, alpha1D-AR, Gpcr8) | |
Results | Reference |
1* | J:43805 Abe-Dohmae S, Takagi Y, Harada N, Autonomous expression of aromatase during development of mouse brain is modulated by neurotransmitters. J Steroid Biochem Mol Biol. 1997 Apr;61(3-6):299-306 |
Adra2a adrenergic receptor, alpha 2a (Synonyms: Adra-2, Adra-2a, alpha2A, alpha2A-adrenergic receptor, alpha(2A)AR, alpha2A-AR) | |
Results | Reference |
1* | J:45271 Wang RX, Limbird LE, Distribution of mRNA encoding three alpha 2-adrenergic receptor subtypes in the developing mouse embryo suggests a role for the alpha 2A subtype in apoptosis. Mol Pharmacol. 1997 Dec;52(6):1071-80 |
Adra2b adrenergic receptor, alpha 2b (Synonyms: [a]2B, a2b-AR, Adra-2b, alpha2B) | |
Results | Reference |
1* | J:45271 Wang RX, Limbird LE, Distribution of mRNA encoding three alpha 2-adrenergic receptor subtypes in the developing mouse embryo suggests a role for the alpha 2A subtype in apoptosis. Mol Pharmacol. 1997 Dec;52(6):1071-80 |
Adra2c adrenergic receptor, alpha 2c (Synonyms: [a]2C, Adra-2c, alpha2C, alpha2-C4, subtype alpha2-C4) | |
Results | Reference |
1* | J:45271 Wang RX, Limbird LE, Distribution of mRNA encoding three alpha 2-adrenergic receptor subtypes in the developing mouse embryo suggests a role for the alpha 2A subtype in apoptosis. Mol Pharmacol. 1997 Dec;52(6):1071-80 |
Adrb1 adrenergic receptor, beta 1 (Synonyms: Adrb-1, beta 1-AR) | |
Results | Reference |
1 | J:241640 Feridooni T, Hotchkiss A, Baguma-Nibasheka M, Zhang F, Allen B, Chinni S, Pasumarthi KBS, Effects of beta-adrenergic receptor drugs on embryonic ventricular cell proliferation and differentiation and their impact on donor cell transplantation. Am J Physiol Heart Circ Physiol. 2017 May 01;312(5):H919-H931 |
Adrb2 adrenergic receptor, beta 2 (Synonyms: Adrb-2, Badm, beta 2-adrenoceptor, beta 2-AR, Gpcr7) | |
Results | Reference |
1 | J:241640 Feridooni T, Hotchkiss A, Baguma-Nibasheka M, Zhang F, Allen B, Chinni S, Pasumarthi KBS, Effects of beta-adrenergic receptor drugs on embryonic ventricular cell proliferation and differentiation and their impact on donor cell transplantation. Am J Physiol Heart Circ Physiol. 2017 May 01;312(5):H919-H931 |
Aebp1 AE binding protein 1 (Synonyms: ACLP) | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1* | J:96324 Ith B, Wei J, Yet SF, Perrella MA, Layne MD, Aortic carboxypeptidase-like protein is expressed in collagen-rich tissues during mouse embryonic development. Gene Expr Patterns. 2005 Apr;5(4):533-7 |
Afdn afadin, adherens junction formation factor (Synonyms: 5033403D15Rik, AF6, Afadin, I-afadin, Mllt4, S-afadin) | |
Results | Reference |
1 | J:206576 Fukuda T, Kominami K, Wang S, Togashi H, Hirata K, Mizoguchi A, Rikitake Y, Takai Y, Aberrant cochlear hair cell attachments caused by Nectin-3 deficiency result in hair bundle abnormalities. Development. 2014 Jan;141(2):399-409 |
1 | J:101707 Inagaki M, Irie K, Ishizaki H, Tanaka-Okamoto M, Morimoto K, Inoue E, Ohtsuka T, Miyoshi J, Takai Y, Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development. Development. 2005 Apr;132(7):1525-37 |
1 | J:294113 Lough KJ, Byrd KM, Descovich CP, Spitzer DC, Bergman AJ, Beaudoin GM 3rd, Reichardt LF, Williams SE, Telophase correction refines division orientation in stratified epithelia. Elife. 2019 Dec 13;8:e49249 |
1 | J:321073 Mollo MR, Antonini D, Mitchell K, Fortugno P, Costanzo A, Dixon J, Brancati F, Missero C, p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis. Exp Dermatol. 2015 Feb;24(2):114-9 |
2 | J:90052 Okabe N, Ozaki-Kuroda K, Nakanishi H, Shimizu K, Takai Y, Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo. Dev Dyn. 2004 May;230(1):174-86 |
1 | J:304680 Skarlatou S, Herent C, Toscano E, Mendes CS, Bouvier J, Zampieri N, Afadin Signaling at the Spinal Neuroepithelium Regulates Central Canal Formation and Gait Selection. Cell Rep. 2020 Jun 9;31(10):107741 |
Aff1 AF4/FMR2 family, member 1 (Synonyms: 9630032B01Rik, Af4, Mllt2h, Rob) | |
Results | Reference |
1* | J:52469 Isnard P, Depetris D, Mattei MG, Ferrier P, Djabali M, cDNA cloning, expression and chromosomal localization of the murine AF-4 gene involved in human leukemia. Mamm Genome. 1998 Dec;9(12):1065-8 |
1* | J:143543 Vogel T, Gruss P, Expression of Leukaemia associated transcription factor Af9/Mllt3 in the cerebral cortex of the mouse. Gene Expr Patterns. 2009 Feb;9(2):83-93 |
Aff2 AF4/FMR2 family, member 2 (Synonyms: Fmr2, Ox19, Oxh) | |
Results | Reference |
1* | J:143543 Vogel T, Gruss P, Expression of Leukaemia associated transcription factor Af9/Mllt3 in the cerebral cortex of the mouse. Gene Expr Patterns. 2009 Feb;9(2):83-93 |
Aff3 AF4/FMR2 family, member 3 (Synonyms: 3222402O04Rik, Laf4, LAF-4) | |
Results | Reference |
1* | J:77889 Britanova O, Lukyanov S, Gruss P, Tarabykin V, The Mouse Laf4 Gene: Exon/Intron Organization, cDNA Sequence, Alternative Splicing, and Expression during Central Nervous System Development. Genomics. 2002 Jul;80(1):31-7 |
Aff4 AF4/FMR2 family, member 4 (Synonyms: Alf4, Laf4l) | |
Results | Reference |
1* | J:301543 Li J, Lee YK, Fu W, Whalen AM, Estable MC, Raftery LA, White K, Weiner L, Brissette JL, Modeling by disruption and a selected-for partner for the nude locus. EMBO Rep. 2020 Dec 28;:e49804 |
1* | J:100030 Urano A, Endoh M, Wada T, Morikawa Y, Itoh M, Kataoka Y, Taki T, Akazawa H, Nakajima H, Komuro I, Yoshida N, Hayashi Y, Handa H, Kitamura T, Nosaka T, Infertility with defective spermiogenesis in mice lacking AF5q31, the target of chromosomal translocation in human infant leukemia. Mol Cell Biol. 2005 Aug;25(15):6834-45 |
Afp alpha fetoprotein (Synonyms: alpha-foetoprotein) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:317045 Cheng W, Li HL, Xi SY, Zhang XF, Zhu Y, Le Xing, Mo YX, Li MM, Kong FE, Zhu WJ, Chen XG, Cui HQ, Cao ZM, Gong YF, Tang YQ, Zhang Y, Guan XY, Ma NF, Liu M, Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma. Nat Commun. 2021 Dec 8;12(1):7142 |
1 | J:16221 Engelhardt NV, Factor VM, Medvinsky AL, Baranov VN, Lazareva MN, Poltoranina VS, Common antigen of oval and biliary epithelial cells (A6) is a differentiation marker of epithelial and erythroid cell lineages in early development of the mouse. Differentiation. 1993 Dec;55(1):19-26 |
2* | J:79500 Gabant P, Forrester L, Nichols J, Van Reeth T, De Mees C, Pajack B, Watt A, Smitz J, Alexandre H, Szpirer C, Szpirer J, Alpha-fetoprotein, the major fetal serum protein, is not essential for embryonic development but is required for female fertility. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12865-70 |
2 | J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90 |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1* | J:146970 Li T, Huang J, Jiang Y, Zeng Y, He F, Zhang MQ, Han Z, Zhang X, Multi-stage analysis of gene expression and transcription regulation in C57/B6 mouse liver development. Genomics. 2009 Mar;93(3):235-42 |
1* | J:302850 Liu M, Chen L, Ma NF, Chow RK, Li Y, Song Y, Chan TH, Fang S, Yang X, Xi S, Jiang L, Li Y, Zeng TT, Li Y, Yuan YF, Guan XY, CHD1L promotes lineage reversion of hepatocellular carcinoma through opening chromatin for key developmental transcription factors. Hepatology. 2016 May;63(5):1544-59 |
1* | J:185112 Park D, Choi D, Lee J, Lim DS, Park C, Male-like sexual behavior of female mouse lacking fucose mutarotase. BMC Genet. 2010;11:62 |
1 | J:180846 Saito K, Ogawa A, Toyofuku K, Hosoi Y, Soma M, Iha M, Kasuga K, Kojima I, Kobayashi M, Relationships between homeoprotein EGAM1C and the expression of the placental prolactin gene family in mouse placentae and trophoblast stem cells. Reproduction. 2011 Feb;141(2):259-68 |
2* | J:187541 Schievenbusch S, Sauer E, Curth HM, Schulte S, Demir M, Toex U, Goeser T, Nierhoff D, Neighbor of punc e 11: expression pattern of the new hepatic stem/progenitor cell marker during murine liver development. Stem Cells Dev. 2012 Sep 20;21(14):2656-66 |
1 | J:178367 Slamon DJ, Cline MJ, Expression of cellular oncogenes during embryonic and fetal development of the mouse. Proc Natl Acad Sci U S A. 1984 Nov;81(22):7141-5 |
2* | J:272586 Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, Yamamoto T, Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019 Feb 15;146(4):dev168146 |
1* | J:140053 Xie Z, Zhang H, Tsai W, Zhang Y, Du Y, Zhong J, Szpirer C, Zhu M, Cao X, Barton MC, Grusby MJ, Zhang WJ, Zinc finger protein ZBTB20 is a key repressor of alpha-fetoprotein gene transcription in liver. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10859-64 |
Agap1 ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 (Synonyms: Centg2, Ggap1, mKIAA1099) | |
Results | Reference |
1* | J:243971 Arnold M, Cross R, Singleton KS, Zlatic S, Chapleau C, Mullin AP, Rolle I, Moore CC, Theibert A, Pozzo-Miller L, Faundez V, Larimore J, The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin. Front Cell Neurosci. 2016;10:218 |
Ager advanced glycosylation end product-specific receptor (Synonyms: RAGE) | |
Results | Reference |
1 | J:270164 Guo M, Du Y, Gokey JJ, Ray S, Bell SM, Adam M, Sudha P, Perl AK, Deshmukh H, Potter SS, Whitsett JA, Xu Y, Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth. Nat Commun. 2019 Jan 3;10(1):37 |
1 | J:264719 Moghieb A, Clair G, Mitchell HD, Kitzmiller J, Zink EM, Kim YM, Petyuk V, Shukla A, Moore RJ, Metz TO, Carson J, McDermott JE, Corley RA, Whitsett JA, Ansong C, Time-resolved proteome profiling of normal lung development. Am J Physiol Lung Cell Mol Physiol. 2018 Jul 1;315(1):L11-L24 |
1 | J:297253 Vila Ellis L, Cain MP, Hutchison V, Flodby P, Crandall ED, Borok Z, Zhou B, Ostrin EJ, Wythe JD, Chen J, Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung. Dev Cell. 2020 Mar 9;52(5):617-630.e6 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Agl amylo-1,6-glucosidase, 4-alpha-glucanotransferase (Synonyms: 1110061O17Rik, 9430004C13Rik, 9630046L06Rik) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
Ago1 argonaute RISC catalytic subunit 1 (Synonyms: argonaute 1, Eif2c1) | |
Results | Reference |
1* | J:160269 Michon F, Tummers M, Kyyronen M, Frilander MJ, Thesleff I, Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol. 2010 Apr 15;340(2):355-68 |
Ago2 argonaute RISC catalytic subunit 2 (Synonyms: 1110029L17Rik, 2310051F07Rik, argonaute 2, Eif2c2, mKIAA1567) | |
Results | Reference |
1* | J:160269 Michon F, Tummers M, Kyyronen M, Frilander MJ, Thesleff I, Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol. 2010 Apr 15;340(2):355-68 |
Ago3 argonaute RISC catalytic subunit 3 (Synonyms: argonaute 3, C130014L07Rik, eIF2C3) | |
Results | Reference |
1* | J:160269 Michon F, Tummers M, Kyyronen M, Frilander MJ, Thesleff I, Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol. 2010 Apr 15;340(2):355-68 |
Ago4 argonaute RISC catalytic subunit 4 (Synonyms: 5730550L01Rik, argonaute 4, Eif2c4) | |
Results | Reference |
1* | J:160269 Michon F, Tummers M, Kyyronen M, Frilander MJ, Thesleff I, Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol. 2010 Apr 15;340(2):355-68 |
Agpat3 1-acylglycerol-3-phosphate O-acyltransferase 3 (Synonyms: D10Jhu12e, LPAAT3) | |
Results | Reference |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
Agr2 anterior gradient 2 (Synonyms: Gob-4, HAG-2, mAG-2, XAG-2) | |
Results | Reference |
1 | J:181435 Gupta D, Harvey SA, Kaminski N, Swamynathan SK, Mouse conjunctival forniceal gene expression during postnatal development and its regulation by Kruppel-like factor 4. Invest Ophthalmol Vis Sci. 2011 Jul;52(8):4951-62 |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
1* | J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903 |
Agrn agrin (Synonyms: Agrin, nmf380, NMF380) | |
Results | Reference |
1 | J:335626 Castillo V, Diaz-Astudillo P, Corrales-Orovio R, San Martin S, Egana JT, Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin. Cells. 2023 Apr 22;12(9) |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:363523 Sun X, Malandraki-Miller S, Kennedy T, Bassat E, Klaourakis K, Zhao J, Gamen E, Vieira JM, Tzahor E, Riley PR, The extracellular matrix protein agrin is essential for epicardial epithelial-to-mesenchymal transition during heart development. Development. 2021 May 1;148(9) |
1 | J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10) |
Agrp agouti related neuropeptide (Synonyms: agouti related protein, Agrt) | |
Results | Reference |
1* | J:308824 de Guia RM, Hassing AS, Ma T, Plucinska K, Holst B, Gerhart-Hines Z, Emanuelli B, Treebak JT, Ablation of Nampt in AgRP neurons leads to neurodegeneration and impairs fasting- and ghrelin-mediated food intake. FASEB J. 2021 May;35(5):e21450 |
Agt angiotensinogen (Synonyms: angiotensin precursor, Aogen, Serpina8) | |
Results | Reference |
1* | J:218046 Cuffe JS, Walton SL, Steane SE, Singh RR, Simmons DG, Moritz KM, The effects of gestational age and maternal hypoxia on the placental renin angiotensin system in the mouse. Placenta. 2014 Nov;35(11):953-61 |
Agtr1a angiotensin II receptor, type 1a (Synonyms: 1810074K20Rik, Agt1ar, Agtr-1a, Agtr1a, Angtr-1a, AT1, AT1a, MGC:37610) | |
Results | Reference |
1 | J:183431 Aboudehen K, Hilliard S, Saifudeen Z, El-Dahr SS, Mechanisms of p53 activation and physiological relevance in the developing kidney. Am J Physiol Renal Physiol. 2012 Apr;302(8):F928-40 |
1* | J:19769 Burson JM, Aguilera G, Gross KW, Sigmund CD, Differential expression of angiotensin receptor 1A and 1B in mouse. Am J Physiol. 1994 Aug;267(2 Pt 1):E260-7 |
1* | J:218046 Cuffe JS, Walton SL, Steane SE, Singh RR, Simmons DG, Moritz KM, The effects of gestational age and maternal hypoxia on the placental renin angiotensin system in the mouse. Placenta. 2014 Nov;35(11):953-61 |
Agtr1b angiotensin II receptor, type 1b (Synonyms: Agtr-1b, Angtr-1b, AT1B) | |
Results | Reference |
1* | J:19769 Burson JM, Aguilera G, Gross KW, Sigmund CD, Differential expression of angiotensin receptor 1A and 1B in mouse. Am J Physiol. 1994 Aug;267(2 Pt 1):E260-7 |
Agtr2 angiotensin II receptor, type 2 (Synonyms: AT2 receptor) | |
Results | Reference |
1* | J:218046 Cuffe JS, Walton SL, Steane SE, Singh RR, Simmons DG, Moritz KM, The effects of gestational age and maternal hypoxia on the placental renin angiotensin system in the mouse. Placenta. 2014 Nov;35(11):953-61 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Ahctf1 AT hook containing transcription factor 1 (Synonyms: 6230412P20Rik, Elys) | |
Results | Reference |
1* | J:79932 Kimura N, Takizawa M, Okita K, Natori O, Igarashi K, Ueno M, Nakashima K, Nobuhisa I, Taga T, Identification of a novel transcription factor, ELYS, expressed predominantly in mouse foetal haematopoietic tissues. Genes Cells. 2002 Apr;7(4):435-46 |
Ahdc1 AT hook, DNA binding motif, containing 1 (Synonyms: D030015G18Rik) | |
Results | Reference |
1* | J:220876 Quintero-Rivera F, Xi QJ, Keppler-Noreuil KM, Lee JH, Higgins AW, Anchan RM, Roberts AE, Seong IS, Fan X, Lage K, Lu LY, Tao J, Hu X, Berezney R, Gelb BD, Kamp A, Moskowitz IP, Lacro RV, Lu W, Morton CC, Gusella JF, Maas RL, MATR3 disruption in human and mouse associated with bicuspid aortic valve, aortic coarctation and patent ductus arteriosus. Hum Mol Genet. 2015 Apr 15;24(8):2375-89 |
Ahi1 Abelson helper integration site 1 (Synonyms: 1700015F03Rik, Ahi-1, D10Bwg0629e, Jouberin) | |
Results | Reference |
2* | J:141833 Doering JE, Kane K, Hsiao YC, Yao C, Shi B, Slowik AD, Dhagat B, Scott DD, Ault JG, Page-McCaw PS, Ferland RJ, Species differences in the expression of Ahi1, a protein implicated in the neurodevelopmental disorder Joubert syndrome, with preferential accumulation to stigmoid bodies. J Comp Neurol. 2008 Nov 10;511(2):238-56 |
Ahr aryl-hydrocarbon receptor (Synonyms: Ah, Ahh, Ahre, bHLHe76, dioxin receptor, In) | |
Results | Reference |
1* | J:29225 Abbott BD, Birnbaum LS, Perdew GH, Developmental expression of two members of a new class of transcription factors: I. Expression of aryl hydrocarbon receptor in the C57BL/6N mouse embryo. Dev Dyn. 1995 Oct;204(2):133-43 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:142539 Vezina CM, Allgeier SH, Moore RW, Lin TM, Bemis JC, Hardin HA, Gasiewicz TA, Peterson RE, Dioxin causes ventral prostate agenesis by disrupting dorsoventral patterning in developing mouse prostate. Toxicol Sci. 2008 Dec;106(2):488-96 |
Ahsg alpha-2-HS-glycoprotein (Synonyms: fetuin-A) | |
Results | Reference |
2 | J:362521 Guo XL, Wang YD, Liu YJ, Chu L, Zhu H, Hu Y, Wu RY, Xie HY, Yu J, Li SP, Xiong CY, Li RY, Ke F, Chen L, Chen GQ, Chen L, Bai F, Enver T, Li GH, Li HF, Hong DL, Fetal hepatocytes protect the HSPC genome via fetuin-A. Nature. 2025 Jan;637(8045):402-411 |
1 | J:320382 Piazzon N, Bernet F, Guihard L, Leonhard WN, Urfer S, Firsov D, Chehade H, Vogt B, Piergiovanni S, Peters DJ, Bonny O, Constam DB, Urine Fetuin-A is a biomarker of autosomal dominant polycystic kidney disease progression. J Transl Med. 2015 Mar 30;13:103 |
Aif1 allograft inflammatory factor 1 (Synonyms: D17H6S50E, G1, Iba1) | |
Results | Reference |
1 | J:273194 Anderson SR, Zhang J, Steele MR, Romero CO, Kautzman AG, Schafer DP, Vetter ML, Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia. J Neurosci. 2019 Mar 13;39(11):2025-2040 |
1 | J:225279 Arno B, Grassivaro F, Rossi C, Bergamaschi A, Castiglioni V, Furlan R, Greter M, Favaro R, Comi G, Becher B, Martino G, Muzio L, Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex. Nat Commun. 2014;5:5611 |
1 | J:336863 Barry-Carroll L, Greulich P, Marshall AR, Riecken K, Fehse B, Askew KE, Li K, Garaschuk O, Menassa DA, Gomez-Nicola D, Microglia colonize the developing brain by clonal expansion of highly proliferative progenitors, following allometric scaling. Cell Rep. 2023 May 30;42(5):112425 |
1 | J:330829 Cabirol MJ, Cardoit L, Courtand G, Mayeur ME, Simmers J, Pascual O, Thoby-Brisson M, Microglia shape the embryonic development of mammalian respiratory networks. Elife. 2022 Nov 2;11:e80352 |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
1 | J:272420 Datta M, Staszewski O, Raschi E, Frosch M, Hagemeyer N, Tay TL, Blank T, Kreutzfeldt M, Merkler D, Ziegler-Waldkirch S, Matthias P, Meyer-Luehmann M, Prinz M, Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner. Immunity. 2018 Mar 20;48(3):514-529.e6 |
1 | J:303325 Fehrenbach MK, Tjwa M, Bechmann I, Krueger M, Decreased microglial numbers in Vav1-Cre(+):dicer knock-out mice suggest a second source of microglia beyond yolk sac macrophages. Ann Anat. 2018 Jul;218:190-198 |
1 | J:334094 Gu X, Heinrich A, Li SY, DeFalco T, Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions. Nat Commun. 2023 Mar 15;14(1):1439 |
1 | J:287499 Hattori Y, Naito Y, Tsugawa Y, Nonaka S, Wake H, Nagasawa T, Kawaguchi A, Miyata T, Transient microglial absence assists postmigratory cortical neurons in proper differentiation. Nat Commun. 2020 Apr 2;11(1):1631 |
1 | J:209564 Karaca E, Weitzer S, Pehlivan D, Shiraishi H, Gogakos T, Hanada T, Jhangiani SN, Wiszniewski W, Withers M, Campbell IM, Erdin S, Isikay S, Franco LM, Gonzaga-Jauregui C, Gambin T, Gelowani V, Hunter JV, Yesil G, Koparir E, Yilmaz S, Brown M, Briskin D, Hafner M, Morozov P, Farazi TA, Bernreuther C, Glatzel M, Trattnig S, Friske J, Kronnerwetter C, Bainbridge MN, Gezdirici A, Seven M, Muzny DM, Boerwinkle E, Ozen M, Clausen T, Tuschl T, Yuksel A, Hess A, Gibbs RA, Martinez J, Penninger JM, Lupski JR, Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function. Cell. 2014 Apr 24;157(3):636-50 |
1 | J:309657 Kishimoto I, Okano T, Nishimura K, Motohashi T, Omori K, Early Development of Resident Macrophages in the Mouse Cochlea Depends on Yolk Sac Hematopoiesis. Front Neurol. 2019;10:1115 |
1 | J:273013 Lee MA, Sitko AA, Khalid S, Shirasu-Hiza M, Mason CA, Spatiotemporal distribution of glia in and around the developing mouse optic tract. J Comp Neurol. 2019 Feb 15;527(3):508-521 |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1 | J:322988 Markert F, Storch A, Hyperoxygenation During Mid-Neurogenesis Accelerates Cortical Development in the Fetal Mouse Brain. Front Cell Dev Biol. 2022;10:732682 |
1 | J:330324 Masuda T, Amann L, Monaco G, Sankowski R, Staszewski O, Krueger M, Del Gaudio F, He L, Paterson N, Nent E, Fernandez-Klett F, Yamasaki A, Frosch M, Fliegauf M, Bosch LFP, Ulupinar H, Hagemeyer N, Schreiner D, Dorrier C, Tsuda M, Grothe C, Joutel A, Daneman R, Betsholtz C, Lendahl U, Knobeloch KP, Lammermann T, Priller J, Kierdorf K, Prinz M, Specification of CNS macrophage subsets occurs postnatally in defined niches. Nature. 2022 Apr;604(7907):740-748 |
1 | J:274409 Masuda T, Sankowski R, Staszewski O, Bottcher C, Amann L, Sagar, Scheiwe C, Nessler S, Kunz P, van Loo G, Coenen VA, Reinacher PC, Michel A, Sure U, Gold R, Grun D, Priller J, Stadelmann C, Prinz M, Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution. Nature. 2019 Feb;566(7744):388-392 |
1 | J:236865 Ramesh V, Bayam E, Cernilogar FM, Bonapace IM, Schulze M, Riemenschneider MJ, Schotta G, Gotz M, Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration. Genes Dev. 2016 Oct 1;30(19):2199-2212 |
1* | J:222345 Rogers SW, Gahring LC, Nicotinic receptor Alpha7 expression during tooth morphogenesis reveals functional pleiotropy. PLoS One. 2012;7(5):e36467 |
1 | J:182209 Schulz C, Gomez Perdiguero E, Chorro L, Szabo-Rogers H, Cagnard N, Kierdorf K, Prinz M, Wu B, Jacobsen SE, Pollard JW, Frampton J, Liu KJ, Geissmann F, A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science. 2012 Apr 6;336(6077):86-90 |
1 | J:326459 Scott EP, Breyak E, Nishinakamura R, Nakagawa Y, The zinc finger transcription factor Sall1 is required for the early developmental transition of microglia in mouse embryos. Glia. 2022 Sep;70(9):1720-1733 |
1 | J:333324 Tominaga K, Sakashita E, Kasashima K, Kuroiwa K, Nagao Y, Iwamori N, Endo H, Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells. Int J Mol Sci. 2023 Jan 20;24(3) |
1* | J:337458 Waldhauser V, Baroti T, Frob F, Wegner M, PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12) |
1 | J:324465 Yu D, Li T, Delpech JC, Zhu B, Kishore P, Koshi T, Luo R, Pratt KJB, Popova G, Nowakowski TJ, Villeda SA, Piao X, Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits. Sci Adv. 2022 May 6;8(18):eabm2545 |
Aire autoimmune regulator | |
Results | Reference |
1 | J:290414 Li J, Gordon J, Chen ELY, Xiao S, Wu L, Zuniga-Pflucker JC, Manley NR, NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development. Development. 2020 Jun 22;147(12):dev178988 |
1 | J:291487 Liu D, Kousa AI, O'Neill KE, Rouse P, Popis M, Farley AM, Tomlinson SR, Ulyanchenko S, Guillemot F, Seymour PA, Jorgensen MC, Serup P, Koch U, Radtke F, Blackburn CC, Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development. Development. 2020 Jun 22;147(12):dev178582 |
1 | J:141379 Yano M, Kuroda N, Han H, Meguro-Horike M, Nishikawa Y, Kiyonari H, Maemura K, Yanagawa Y, Obata K, Takahashi S, Ikawa T, Satoh R, Kawamoto H, Mouri Y, Matsumoto M, Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance. J Exp Med. 2008 Nov 24;205(12):2827-38 |
2* | J:63747 Zuklys S, Balciunaite G, Agarwal A, Fasler-Kan E, Palmer E, Hollander GA, Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). J Immunol. 2000 Aug 15;165(4):1976-83 |
Airn antisense Igf2r RNA (Synonyms: 2810051F02Rik, 2810434M15Rik, Air, B930018I07Rik, D17Ertd663e) | |
Results | Reference |
1 | J:276632 Sleutels F, Tjon G, Ludwig T, Barlow DP, Imprinted silencing of Slc22a2 and Slc22a3 does not need transcriptional overlap between Igf2r and Air. EMBO J. 2003 Jul 15;22(14):3696-704 |
Ajuba ajuba LIM protein (Synonyms: Jub) | |
Results | Reference |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
Ak7 adenylate kinase 7 (Synonyms: 4930502N02Rik) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Akap6 A kinase anchor protein 6 | |
Results | Reference |
1 | J:358347 Dias AP, Rehmani T, Salih M, Tuana B, Tail-anchored membrane protein SLMAP3 is essential for targeting centrosomal proteins to the nuclear envelope in skeletal myogenesis. Open Biol. 2024 Oct;14(10):240094 |
Akap12 A kinase anchor protein 12 (Synonyms: Srcs5, SSeCKS, Tsga12) | |
Results | Reference |
1 | J:359451 Amato CM, Xu X, Yao HH, An extragenital cell population contributes to urethra closure during mouse penis development. Sci Adv. 2024 Dec 6;10(49):eadp0673 |
1 | J:307093 Amato CM, Yao HH, Developmental and sexual dimorphic atlas of the prenatal mouse external genitalia at the single-cell level. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2103856118 |
Akp1 alkaline phosphatase 1 (Synonyms: Akp-1) | |
Results | Reference |
1 | J:178499 Joeng KS, Schumacher CA, Zylstra-Diegel CR, Long F, Williams BO, Lrp5 and Lrp6 redundantly control skeletal development in the mouse embryo. Dev Biol. 2011 Nov 15;359(2):222-9 |
Akr1b7 aldo-keto reductase family 1, member B7 (Synonyms: Avdp, MVDP) | |
Results | Reference |
1 | J:30133 Lau ET, Cao D, Lin C, Chung SK, Chung SS, Tissue-specific expression of two aldose reductase-like genes in mice: abundant expression of mouse vas deferens protein and fibroblast growth factor-regulated protein in the adrenal gland. Biochem J. 1995 Dec 1;312(Pt 2):609-15 |
2 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
Akr1b8 aldo-keto reductase family 1, member B8 (Synonyms: Fgfrp, Fgrp) | |
Results | Reference |
1 | J:30133 Lau ET, Cao D, Lin C, Chung SK, Chung SS, Tissue-specific expression of two aldose reductase-like genes in mice: abundant expression of mouse vas deferens protein and fibroblast growth factor-regulated protein in the adrenal gland. Biochem J. 1995 Dec 1;312(Pt 2):609-15 |
Akr1c6 aldo-keto reductase family 1, member C6 (Synonyms: 3alpha-HSD, Akr1c1, estradiol 17-beta-dehydrogenase (A-specific), Hsd17b5) | |
Results | Reference |
1 | J:222168 Huang CC, Kraft C, Moy N, Ng L, Forrest D, A Novel Population of Inner Cortical Cells in the Adrenal Gland That Displays Sexually Dimorphic Expression of Thyroid Hormone Receptor-beta1. Endocrinology. 2015 Jun;156(6):2338-48 |
1 | J:161760 Provost PR, Simard M, Tremblay Y, A link between lung androgen metabolism and the emergence of mature epithelial type II cells. Am J Respir Crit Care Med. 2004 Aug 1;170(3):296-305 |
1* | J:106945 Tremblay Y, Provost PR, 17beta-HSD type 5 expression and the emergence of differentiated epithelial Type II cells in fetal lung: A novel role for androgen during the surge of surfactant. Mol Cell Endocrinol. 2006 Mar 27;248(1-2):118-25 |
Akr1c14 aldo-keto reductase family 1, member C14 (Synonyms: 9030611N15Rik) | |
Results | Reference |
1 | J:323376 Vacher CM, Lacaille H, O'Reilly JJ, Salzbank J, Bakalar D, Sebaoui S, Liere P, Clarkson-Paredes C, Sasaki T, Sathyanesan A, Kratimenos P, Ellegood J, Lerch JP, Imamura Y, Popratiloff A, Hashimoto-Torii K, Gallo V, Schumacher M, Penn AA, Placental endocrine function shapes cerebellar development and social behavior. Nat Neurosci. 2021 Oct;24(10):1392-1401 |
Akr1c18 aldo-keto reductase family 1, member C18 (Synonyms: 20alpha-HSD, 20alpha-hydroxysteroid dehydrogenase) | |
Results | Reference |
1 | J:130001 Roizen JD, Asada M, Tong M, Tai HH, Muglia LJ, Preterm Birth without Progesterone Withdrawal in 15-Hydroxyprostaglandin Dehydrogenase Hypomorphic Mice. Mol Endocrinol. 2008 Jan;22(1):105-12 |
Akt1 thymoma viral proto-oncogene 1 (Synonyms: Akt, PKB, PKB/Akt, PKBalpha) | |
Results | Reference |
1 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1* | J:47692 Altomare DA, Lyons GE, Mitsuuchi Y, Cheng JQ, Testa JR, Akt2 mRNA is highly expressed in embryonic brown fat and the AKT2 kinase is activated by insulin. Oncogene. 1998 May 7;16(18):2407-11 |
2 | J:255164 Broche B, Ben Fradj S, Aguilar E, Sancerni T, Benard M, Makaci F, Berthault C, Scharfmann R, Alves-Guerra MC, Duvillie B, Mitochondrial Protein UCP2 Controls Pancreas Development. Diabetes. 2018 Jan;67(1):78-84 |
1 | J:242729 Ding X, Bloch W, Iden S, Ruegg MA, Hall MN, Leptin M, Partridge L, Eming SA, mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation. Nat Commun. 2016 Oct 27;7:13226 |
1 | J:332407 Gu Y, Zhou Y, Ju S, Liu X, Zhang Z, Guo J, Gao J, Zang J, Sun H, Chen Q, Wang J, Xu J, Xu Y, Chen Y, Guo Y, Dai J, Ma H, Wang C, Jin G, Li C, Xia Y, Shen H, Yang Y, Guo X, Hu Z, Multi-omics profiling visualizes dynamics of cardiac development and functions. Cell Rep. 2022 Dec 27;41(13):111891 |
1 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1 | J:216228 Inoue S, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y, New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet. 2014 Dec 15;23(24):6553-66 |
1* | J:83700 Koyama N, Kashimata M, Sakashita H, Sakagami H, Gresik EW, EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland. Dev Dyn. 2003 Jun;227(2):216-26 |
1* | J:238086 Kusano R, Fujita K, Shinoda Y, Nagaura Y, Kiyonari H, Abe T, Watanabe T, Matsui Y, Fukaya M, Sakagami H, Sato T, Funahashi JI, Ohnishi M, Tamura S, Kobayashi T, Targeted disruption of the mouse protein phosphatase ppm1l gene leads to structural abnormalities in the brain. FEBS Lett. 2016 Oct;590(20):3606-3615 |
1 | J:340406 Lai Y, Guo Y, Liao C, Mao C, Liu J, Ren C, Yang W, Luo L, Chen W, Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development. Sci Rep. 2023 Sep 13;13(1):15170 |
1 | J:312817 Lei X, Jiao J, UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling. Stem Cell Reports. 2018 Apr 10;10(4):1193-1207 |
1 | J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410 |
1 | J:298839 Lindhurst MJ, Li W, Laughner N, Shwetar JJ, Kondolf HC, Ma X, Mukouyama YS, Biesecker LG, Ubiquitous expression of Akt1 p.(E17K) results in vascular defects and embryonic lethality in mice. Hum Mol Genet. 2020 Dec 18;29(20):3350-3360 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1 | J:97328 Nishio S, Hatano M, Nagata M, Horie S, Koike T, Tokuhisa T, Mochizuki T, Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation. J Clin Invest. 2005 Apr 1;115(4):910-918 |
2 | J:122775 O'Shaughnessy RF, Welti JC, Cooke JC, Avilion AA, Monks B, Birnbaum MJ, Byrne C, AKT-dependent HspB1 (Hsp27) activity in epidermal differentiation. J Biol Chem. 2007 Jun 8;282(23):17297-305 |
2 | J:153617 O'Shaughnessy RF, Welti JC, Sully K, Byrne C, Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development. Development. 2009 Oct;136(20):3423-31 |
1* | J:319569 Ohira T, Spear D, Azimi N, Andreeva V, Yelick PC, Chemerin-ChemR23 signaling in tooth development. J Dent Res. 2012 Dec;91(12):1147-53 |
1 | J:158679 Pan Y, Carbe C, Powers A, Feng GS, Zhang X, Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development. Development. 2010 Apr;137(7):1085-93 |
1 | J:346063 Rehmani T, Dias AP, Kamal M, Salih M, Tuana BS, Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway. Int J Mol Sci. 2024 Mar 1;25(5) |
1 | J:125303 Schaeper U, Vogel R, Chmielowiec J, Huelsken J, Rosario M, Birchmeier W, Distinct requirements for Gab1 in Met and EGF receptor signaling in vivo. Proc Natl Acad Sci U S A. 2007 Sep 25;104(39):15376-81 |
1 | J:225743 Um SH, Sticker-Jantscheff M, Chau GC, Vintersten K, Mueller M, Gangloff YG, Adams RH, Spetz JF, Elghazi L, Pfluger PT, Pende M, Bernal-Mizrachi E, Tauler A, Tschop MH, Thomas G, Kozma SC, S6K1 controls pancreatic beta cell size independently of intrauterine growth restriction. J Clin Invest. 2015 Jul 1;125(7):2736-47 |
1 | J:309451 Vinsland E, Baskaran P, Mihaylov SR, Hobbs C, Wood H, Bouybayoune I, Shah K, Houart C, Tee AR, Murn J, Fernandes C, Bateman JM, The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021 Aug 11;11(1):16299 |
1 | J:99501 Wang J, Ito T, Udaka N, Okudela K, Yazawa T, Kitamura H, PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung. Tissue Cell. 2005 Feb;37(1):25-35 |
1 | J:316121 Wang JR, Wang CJ, Xu CY, Wu XK, Hong D, Shi W, Gong Y, Chen HX, Long F, Wu XM, Signaling Cascades Governing Cdc42-Mediated Chondrogenic Differentiation and Mensenchymal Condensation. Genetics. 2016 Mar;202(3):1055-69 |
1 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
1 | J:305176 Wei Y, Han X, Zhao C, PDK1 regulates the survival of the developing cortical interneurons. Mol Brain. 2020 May 4;13(1):65 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
1 | J:285763 Xu M, Han X, Liu R, Li Y, Qi C, Yang Z, Zhao C, Gao J, PDK1 Deficit Impairs the Development of the Dentate Gyrus in Mice. Cereb Cortex. 2019 Mar 1;29(3):1185-1198 |
1 | J:199582 Youssef G, Gerner L, Naeem AS, Ralph O, Ono M, O'Neill CA, O'Shaughnessy RF, Rab3Gap1 mediates exocytosis of Claudin-1 and tight junction formation during epidermal barrier acquisition. Dev Biol. 2013 Aug 15;380(2):274-85 |
1 | J:168571 Zou J, Zhou L, Du XX, Ji Y, Xu J, Tian J, Jiang W, Zou Y, Yu S, Gan L, Luo M, Yang Q, Cui Y, Yang W, Xia X, Chen M, Zhao X, Shen Y, Chen PY, Worley PF, Xiao B, Rheb1 is required for mTORC1 and myelination in postnatal brain development. Dev Cell. 2011 Jan 18;20(1):97-108 |
Akt2 thymoma viral proto-oncogene 2 (Synonyms: 2410016A19Rik, PKB, PKBbeta) | |
Results | Reference |
1* | J:47692 Altomare DA, Lyons GE, Mitsuuchi Y, Cheng JQ, Testa JR, Akt2 mRNA is highly expressed in embryonic brown fat and the AKT2 kinase is activated by insulin. Oncogene. 1998 May 7;16(18):2407-11 |
2 | J:122775 O'Shaughnessy RF, Welti JC, Cooke JC, Avilion AA, Monks B, Birnbaum MJ, Byrne C, AKT-dependent HspB1 (Hsp27) activity in epidermal differentiation. J Biol Chem. 2007 Jun 8;282(23):17297-305 |
Alas1 aminolevulinic acid synthase 1 (Synonyms: 5-aminolevulinate synthase, Alas-1, ALAS-N, succinyl-CoA: glycine C-succinyl transferase) | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
Alas2 aminolevulinic acid synthase 2, erythroid (Synonyms: 5-aminolevulinate synthase, ALAS, Alas-2, ALAS-E, ALASE, erythroid-specific ALAS) | |
Results | Reference |
1 | J:116324 Nakajima O, Okano S, Harada H, Kusaka T, Gao X, Hosoya T, Suzuki N, Takahashi S, Yamamoto M, Transgenic rescue of erythroid 5-aminolevulinate synthase-deficient mice results in the formation of ring sideroblasts and siderocytes. Genes Cells. 2006 Jun;11(6):685-700 |
1* | J:285404 Ueda T, Yokota T, Okuzaki D, Uno Y, Mashimo T, Kubota Y, Sudo T, Ishibashi T, Shingai Y, Doi Y, Ozawa T, Nakai R, Tanimura A, Ichii M, Ezoe S, Shibayama H, Oritani K, Kanakura Y, Endothelial Cell-Selective Adhesion Molecule Contributes to the Development of Definitive Hematopoiesis in the Fetal Liver. Stem Cell Reports. 2019 Dec 10;13(6):992-1005 |
Alb albumin (Synonyms: Alb-1, Alb1) | |
Results | Reference |
1* | J:85152 Anzai H, Kamiya A, Shirato H, Takeuchi T, Miyajima A, Impaired differentiation of fetal hepatocytes in homozygous jumonji mice. Mech Dev. 2003 Jul;120(7):791-800 |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:117766 Chang J, Nicolas E, Marks D, Sander C, Lerro A, Buendia MA, Xu C, Mason WS, Moloshok T, Bort R, Zaret KS, Taylor JM, miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1. RNA Biol. 2004 Jul;1(2):106-13 |
1 | J:317045 Cheng W, Li HL, Xi SY, Zhang XF, Zhu Y, Le Xing, Mo YX, Li MM, Kong FE, Zhu WJ, Chen XG, Cui HQ, Cao ZM, Gong YF, Tang YQ, Zhang Y, Guan XY, Ma NF, Liu M, Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma. Nat Commun. 2021 Dec 8;12(1):7142 |
1 | J:267596 Escot S, Willnow D, Naumann H, Di Francescantonio S, Spagnoli FM, Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors. Nat Commun. 2018 Nov 30;9(1):5082 |
1* | J:79500 Gabant P, Forrester L, Nichols J, Van Reeth T, De Mees C, Pajack B, Watt A, Smitz J, Alexandre H, Szpirer C, Szpirer J, Alpha-fetoprotein, the major fetal serum protein, is not essential for embryonic development but is required for female fertility. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12865-70 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
1* | J:146970 Li T, Huang J, Jiang Y, Zeng Y, He F, Zhang MQ, Han Z, Zhang X, Multi-stage analysis of gene expression and transcription regulation in C57/B6 mouse liver development. Genomics. 2009 Mar;93(3):235-42 |
1* | J:302850 Liu M, Chen L, Ma NF, Chow RK, Li Y, Song Y, Chan TH, Fang S, Yang X, Xi S, Jiang L, Li Y, Zeng TT, Li Y, Yuan YF, Guan XY, CHD1L promotes lineage reversion of hepatocellular carcinoma through opening chromatin for key developmental transcription factors. Hepatology. 2016 May;63(5):1544-59 |
1* | J:187541 Schievenbusch S, Sauer E, Curth HM, Schulte S, Demir M, Toex U, Goeser T, Nierhoff D, Neighbor of punc e 11: expression pattern of the new hepatic stem/progenitor cell marker during murine liver development. Stem Cells Dev. 2012 Sep 20;21(14):2656-66 |
1* | J:272586 Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, Yamamoto T, Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019 Feb 15;146(4):dev168146 |
Alcam activated leukocyte cell adhesion molecule (Synonyms: BEN, CD166, DM-GRASP, MGC:27910, MuSC, SC1) | |
Results | Reference |
1 | J:308786 Delgado C, Bu L, Zhang J, Liu FY, Sall J, Liang FX, Furley AJ, Fishman GI, Neural cell adhesion molecule is required for ventricular conduction system development. Development. 2021 Jun 1;148(11):dev199431 |
1* | J:63767 Fraboulet S, Schmidt-Petri T, Dhouailly D, Pourquie O, Expression of DM-GRASP/BEN in the developing mouse spinal cord and various epithelia. Mech Dev. 2000 Jul;95(1-2):221-4 |
2* | J:229257 Gu Z, Imai F, Kim IJ, Fujita H, Katayama Ki, Mori K, Yoshihara Y, Yoshida Y, Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550 |
1* | J:114661 Lyu YL, Lin CP, Azarova AM, Cai L, Wang JC, Liu LF, Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Mol Cell Biol. 2006 Nov;26(21):7929-41 |
1 | J:263065 Ogawa T, Li Y, Lua I, Hartner A, Asahina K, Isolation of a unique hepatic stellate cell population expressing integrin alpha8 from embryonic mouse livers. Dev Dyn. 2018 Jun;247(6):867-881 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1 | J:50282 Sekine-Aizawa Y, Omori A, Fujita SC, MuSC, a novel member of the immunoglobulin superfamily, is expressed in neurons of a subset of cranial sensory ganglia in the mouse embryo. Eur J Neurosci. 1998 Sep;10(9):2810-24 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 (Synonyms: Ahd-2, Ahd2, ALDH1, E1, Raldh1) | |
Results | Reference |
1* | J:167740 Alfano G, Conte I, Caramico T, Avellino R, Arno B, Pizzo MT, Tanimoto N, Beck SC, Huber G, Dolle P, Seeliger MW, Banfi S, Vax2 regulates retinoic acid distribution and cone opsin expression in the vertebrate eye. Development. 2011 Jan;138(2):261-71 |
1* | J:256937 Bohnenpoll T, Weiss AC, Labuhn M, Ludtke TH, Trowe MO, Kispert A, Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter. Sci Rep. 2017 Nov 1;7(1):14803 |
1* | J:216602 Bryant SL, Francis JC, Lokody IB, Wang H, Risbridger GP, Loveland KL, Swain A, Sex specific retinoic acid signaling is required for the initiation of urogenital sinus bud development. Dev Biol. 2014 Nov 15;395(2):209-17 |
1 | J:244957 El Shahawy M, Reibring CG, Neben CL, Hallberg K, Marangoni P, Harfe BD, Klein OD, Linde A, Gritli-Linde A, Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid. PLoS Genet. 2017 Jul;13(7):e1006914 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1 | J:121381 Hu P, Zhang M, Napoli JL, Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal. Biochim Biophys Acta. 2007 Apr;1770(4):694-705 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
1 | J:316129 Login H, Butowt R, Bohm S, Activity-dependent and graded BACE1 expression in the olfactory epithelium is mediated by the retinoic acid metabolizing enzyme CYP26B1. Brain Struct Funct. 2015 Jul;220(4):2143-57 |
1 | J:310537 Mesman S, Smidt MP, Tcf12 Is Involved in Early Cell-Fate Determination and Subset Specification of Midbrain Dopamine Neurons. Front Mol Neurosci. 2017;10:353 |
1* | J:73810 Niederreither K, Fraulob V, Garnier JM, Chambon P, Dolle P, Differential expression of retinoic acid-synthesizing (RALDH) enzymes during fetal development and organ differentiation in the mouse. Mech Dev. 2002 Jan;110(1-2):165-71 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1* | J:134349 Vezina CM, Allgeier SH, Fritz WA, Moore RW, Strerath M, Bushman W, Peterson RE, Retinoic acid induces prostatic bud formation. Dev Dyn. 2008 May;237(5):1321-33 |
Aldh1a2 aldehyde dehydrogenase family 1, subfamily A2 (Synonyms: Aldh1a7, Raldh2, retinaldehyde dehydrogenase) | |
Results | Reference |
1* | J:73809 Abu-Abed S, MacLean G, Fraulob V, Chambon P, Petkovich M, Dolle P, Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis. Mech Dev. 2002 Jan;110(1-2):173-7 |
2* | J:256937 Bohnenpoll T, Weiss AC, Labuhn M, Ludtke TH, Trowe MO, Kispert A, Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter. Sci Rep. 2017 Nov 1;7(1):14803 |
1* | J:216602 Bryant SL, Francis JC, Lokody IB, Wang H, Risbridger GP, Loveland KL, Swain A, Sex specific retinoic acid signaling is required for the initiation of urogenital sinus bud development. Dev Biol. 2014 Nov 15;395(2):209-17 |
2 | J:192176 Casanova JC, Travisano S, de la Pompa JL, Epithelial-to-mesenchymal transition in epicardium is independent of snail1. Genesis. 2013 Jan;51(1):32-40 |
1* | J:156170 Castillo HA, Cravo RM, Azambuja AP, Simoes-Costa MS, Sura-Trueba S, Gonzalez J, Slonimsky E, Almeida K, Abreu JG, de Almeida MA, Sobreira TP, de Oliveira SH, de Oliveira PS, Signore IA, Colombo A, Concha ML, Spengler TS, Bronner-Fraser M, Nobrega M, Rosenthal N, Xavier-Neto J, Insights into the organization of dorsal spinal cord pathways from an evolutionarily conserved raldh2 intronic enhancer. Development. 2010 Feb;137(3):507-18 |
1 | J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767 |
1 | J:273024 DiNuoscio G, Atit RP, Wnt/beta-catenin signaling in the mouse embryonic cranial mesenchyme is required to sustain the emerging differentiated meningeal layers. Genesis. 2019 Jan;57(1):e23279 |
1 | J:244957 El Shahawy M, Reibring CG, Neben CL, Hallberg K, Marangoni P, Harfe BD, Klein OD, Linde A, Gritli-Linde A, Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid. PLoS Genet. 2017 Jul;13(7):e1006914 |
1 | J:121381 Hu P, Zhang M, Napoli JL, Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal. Biochim Biophys Acta. 2007 Apr;1770(4):694-705 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1 | J:327415 Jing J, Feng J, Yuan Y, Guo T, Lei J, Pei F, Ho TV, Chai Y, Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022 Aug 16;13(1):4803 |
1 | J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522 |
1* | J:62941 Malpel S, Mendelsohn C, Cardoso WV, Regulation of retinoic acid signaling during lung morphogenesis. Development. 2000 Jul;127(14):3057-67 |
1 | J:341276 Matrongolo MJ, Ho-Nguyen KT, Jain M, Ang PS, Reddy A, Schaper S, Tischfield MA, Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice. Development. 2023 Sep 15;150(18):dev201381 |
1 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
1* | J:73810 Niederreither K, Fraulob V, Garnier JM, Chambon P, Dolle P, Differential expression of retinoic acid-synthesizing (RALDH) enzymes during fetal development and organ differentiation in the mouse. Mech Dev. 2002 Jan;110(1-2):165-71 |
1* | J:108109 Oxburgh L, Chu GC, Michael SK, Robertson EJ, TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development. 2004 Sep;131(18):4593-605 |
1* | J:70836 Romand R, Albuisson E, Niederreither K, Fraulob V, Chambon P, Dolle P, Specific expression of the retinoic acid-synthesizing enzyme RALDH2 during mouse inner ear development. Mech Dev. 2001 Aug;106(1-2):185-9 |
2 | J:361958 Straube P, Beckers A, Jany UWH, Bergmann F, Ludtke TH, Rudat C, Trowe MO, Peters I, Klopf MG, Mamo TM, Kispert A, Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter. Development. 2025 Feb 1;152(3) |
1 | J:336858 Vallecillo-Garcia P, Orgeur M, Comai G, Poehle-Kronnawitter S, Fischer C, Gloger M, Dumas CE, Giesecke-Thiel C, Sauer S, Tajbakhsh S, Hopken UE, Stricker S, A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation. Immunity. 2023 Jun 13;56(6):1204-1219.e8 |
1* | J:134349 Vezina CM, Allgeier SH, Fritz WA, Moore RW, Strerath M, Bushman W, Peterson RE, Retinoic acid induces prostatic bud formation. Dev Dyn. 2008 May;237(5):1321-33 |
Aldh1a3 aldehyde dehydrogenase family 1, subfamily A3 (Synonyms: ALDH6, RALDH3, retinaldehyde dehydrogenase 3, V1) | |
Results | Reference |
1* | J:167740 Alfano G, Conte I, Caramico T, Avellino R, Arno B, Pizzo MT, Tanimoto N, Beck SC, Huber G, Dolle P, Seeliger MW, Banfi S, Vax2 regulates retinoic acid distribution and cone opsin expression in the vertebrate eye. Development. 2011 Jan;138(2):261-71 |
2* | J:256937 Bohnenpoll T, Weiss AC, Labuhn M, Ludtke TH, Trowe MO, Kispert A, Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter. Sci Rep. 2017 Nov 1;7(1):14803 |
1* | J:216602 Bryant SL, Francis JC, Lokody IB, Wang H, Risbridger GP, Loveland KL, Swain A, Sex specific retinoic acid signaling is required for the initiation of urogenital sinus bud development. Dev Biol. 2014 Nov 15;395(2):209-17 |
1 | J:244957 El Shahawy M, Reibring CG, Neben CL, Hallberg K, Marangoni P, Harfe BD, Klein OD, Linde A, Gritli-Linde A, Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid. PLoS Genet. 2017 Jul;13(7):e1006914 |
1 | J:121381 Hu P, Zhang M, Napoli JL, Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal. Biochim Biophys Acta. 2007 Apr;1770(4):694-705 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1* | J:63701 Li H, Wagner E, McCaffery P, Smith D, Andreadis A, Drager UC, A retinoic acid synthesizing enzyme in ventral retina and telencephalon of the embryonic mouse. Mech Dev. 2000 Jul;95(1-2):283-9 |
1* | J:73810 Niederreither K, Fraulob V, Garnier JM, Chambon P, Dolle P, Differential expression of retinoic acid-synthesizing (RALDH) enzymes during fetal development and organ differentiation in the mouse. Mech Dev. 2002 Jan;110(1-2):165-71 |
1 | J:316584 Outhwaite JE, Natale BV, Natale DR, Simmons DG, Expression of aldehyde dehydrogenase family 1, member A3 in glycogen trophoblast cells of the murine placenta. Placenta. 2015 Mar;36(3):304-11 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1* | J:134349 Vezina CM, Allgeier SH, Fritz WA, Moore RW, Strerath M, Bushman W, Peterson RE, Retinoic acid induces prostatic bud formation. Dev Dyn. 2008 May;237(5):1321-33 |
1* | J:92057 Waclaw RR, Wang B, Campbell K, The homeobox gene Gsh2 is required for retinoid production in the embryonic mouse telencephalon. Development. 2004 Aug;131(16):4013-20 |
Aldh1b1 aldehyde dehydrogenase 1 family, member B1 (Synonyms: 2700007F14Rik) | |
Results | Reference |
1 | J:232360 Anastasiou V, Ninou E, Alexopoulou D, Stertmann J, Muller A, Dahl A, Solimena M, Speier S, Serafimidis I, Gavalas A, Aldehyde dehydrogenase activity is necessary for beta cell development and functionality in mice. Diabetologia. 2016 Jan;59(1):139-50 |
1* | J:192460 Ioannou M, Serafimidis I, Arnes L, Sussel L, Singh S, Vasiliou V, Gavalas A, ALDH1B1 is a potential stem/progenitor marker for multiple pancreas progenitor pools. Dev Biol. 2013 Feb 1;374(1):153-63 |
Aldh1l1 aldehyde dehydrogenase 1 family, member L1 (Synonyms: 1810048F20Rik, Fthfd) | |
Results | Reference |
1* | J:134595 Anthony TE, Heintz N, The folate metabolic enzyme ALDH1L1 is restricted to the midline of the early CNS, suggesting a role in human neural tube defects. J Comp Neurol. 2007 Jan 10;500(2):368-83 |
1 | J:313961 Caramello A, Galichet C, Rizzoti K, Lovell-Badge R, Dentate gyrus development requires a cortical hem-derived astrocytic scaffold. Elife. 2021 Jan 4;10:e63904 |
1 | J:275375 Sun S, Zhu XJ, Huang H, Guo W, Tang T, Xie B, Xu X, Zhang Z, Shen Y, Dai ZM, Qiu M, WNT signaling represses astrogliogenesis via Ngn2-dependent direct suppression of astrocyte gene expression. Glia. 2019 Jul;67(7):1333-1343 |
Aldh8a1 aldehyde dehydrogenase 8 family, member A1 (Synonyms: RALDH4) | |
Results | Reference |
1 | J:121381 Hu P, Zhang M, Napoli JL, Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal. Biochim Biophys Acta. 2007 Apr;1770(4):694-705 |
Aldoa aldolase A, fructose-bisphosphate (Synonyms: Aldo-1, Aldo1) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
1* | J:2985 Colbert MC, Ciejek-Baez E, The proximal promoter of the aldolase A gene remains active during myogenesis in vitro and muscle development in vivo. Dev Biol. 1992 Jan;149(1):66-79 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
Aldoc aldolase C, fructose-bisphosphate (Synonyms: Aldo3, Aldolase C, Scrg2, zebrin II) | |
Results | Reference |
1 | J:219427 Glasgow SM, Zhu W, Stolt CC, Huang TW, Chen F, LoTurco JJ, Neul JL, Wegner M, Mohila C, Deneen B, Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subtypes. Nat Neurosci. 2014 Oct;17(10):1322-9 |
Alk anaplastic lymphoma kinase (Synonyms: CD246, Tcrz) | |
Results | Reference |
2* | J:109486 Vernersson E, Khoo NK, Henriksson ML, Roos G, Palmer RH, Hallberg B, Characterization of the expression of the ALK receptor tyrosine kinase in mice. Gene Expr Patterns. 2006 Jun;6(5):448-61 |
Alkbh8 alkB homolog 8, tRNA methyltransferase (Synonyms: 4930562C03Rik, 8030431D03Rik, 9430088N01Rik, Abh8) | |
Results | Reference |
1* | J:354244 Nakai M, Hase H, Zhao Y, Okawa K, Honda K, Ikuma K, Kitae K, Tsujikawa K, RNA-modifying enzyme Alkbh8 is involved in mouse embryonic development. iScience. 2024 Sep 20;27(9):110777 |
Alox12b arachidonate 12-lipoxygenase, 12R type (Synonyms: 12R-LOX, Aloxe2, e-LOX2) | |
Results | Reference |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
1* | J:51421 Sun D, McDonnell M, Chen XS, Lakkis MM, Li H, Isaacs SN, Elsea SH, Patel PI, Funk CD, Human 12(R)-lipoxygenase and the mouse ortholog. Molecular cloning, expression, and gene chromosomal assignment. J Biol Chem. 1998 Dec 11;273(50):33540-7 |
Alox15 arachidonate 15-lipoxygenase (Synonyms: 12-LO, Alox12l, L-12LO) | |
Results | Reference |
2 | J:331834 Zhang F, Sun K, Wang WS, Identification of a Feed-Forward Loop Between 15(S)-HETE and PGE2 in Human Amnion at Parturition. J Lipid Res. 2022 Oct 4;63(11):100294 |
Alpi alkaline phosphatase, intestinal (Synonyms: 2010001C14Rik) | |
Results | Reference |
1* | J:279777 Arno B, Galli F, Roostalu U, Aldeiri BM, Miyake T, Albertini A, Bragg L, Prehar S, McDermott JC, Cartwright EJ, Cossu G, TNAP limits TGF-beta-dependent cardiac and skeletal muscle fibrosis by inactivating the SMAD2/3 transcription factors. J Cell Sci. 2019 Aug 8;132(15):jcs234948 |
1 | J:283354 Guiu J, Hannezo E, Yui S, Demharter S, Ulyanchenko S, Maimets M, Jorgensen A, Perlman S, Lundvall L, Mamsen LS, Larsen A, Olesen RH, Andersen CY, Thuesen LL, Hare KJ, Pers TH, Khodosevich K, Simons BD, Jensen KB, Tracing the origin of adult intestinal stem cells. Nature. 2019 Jun;570(7759):107-111 |
1* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
Alpl alkaline phosphatase, liver/bone/kidney (Synonyms: Akp-2, Akp2, ALP, TNAP, TNSALP) | |
Results | Reference |
1* | J:279777 Arno B, Galli F, Roostalu U, Aldeiri BM, Miyake T, Albertini A, Bragg L, Prehar S, McDermott JC, Cartwright EJ, Cossu G, TNAP limits TGF-beta-dependent cardiac and skeletal muscle fibrosis by inactivating the SMAD2/3 transcription factors. J Cell Sci. 2019 Aug 8;132(15):jcs234948 |
1 | J:181527 Chaible LM, Sanches DS, Cogliati B, Mennecier G, Dagli ML, Delayed osteoblastic differentiation and bone development in Cx43 knockout mice. Toxicol Pathol. 2011 Dec;39(7):1046-55 |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1* | J:292270 Ideno H, Nakashima K, Komatsu K, Araki R, Abe M, Arai Y, Kimura H, Shinkai Y, Tachibana M, Nifuji A, G9a is involved in the regulation of cranial bone formation through activation of Runx2 function during development. Bone. 2020 Aug;137:115332 |
1 | J:256071 Iyyanar PPR, Nazarali AJ, Hoxa2 Inhibits Bone Morphogenetic Protein Signaling during Osteogenic Differentiation of the Palatal Mesenchyme. Front Physiol. 2017;8:929 |
1 | J:143588 Kamiya N, Ye L, Kobayashi T, Mochida Y, Yamauchi M, Kronenberg HM, Feng JQ, Mishina Y, BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development. 2008 Nov;135(22):3801-11 |
1 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
1 | J:124088 Soung do Y, Dong Y, Wang Y, Zuscik MJ, Schwarz EM, O'Keefe RJ, Drissi H, Runx3/AML2/Cbfa3 regulates early and late chondrocyte differentiation. J Bone Miner Res. 2007 Aug;22(8):1260-70 |
1 | J:333326 Suh J, Kim NK, Shim W, Lee SH, Kim HJ, Moon E, Sesaki H, Jang JH, Kim JE, Lee YS, Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab. 2023 Feb 7;35(2):345-360.e7 |
Alppl2 alkaline phosphatase, placental-like 2 (Synonyms: Akp5, D1Ertd816e) | |
Results | Reference |
1* | J:279777 Arno B, Galli F, Roostalu U, Aldeiri BM, Miyake T, Albertini A, Bragg L, Prehar S, McDermott JC, Cartwright EJ, Cossu G, TNAP limits TGF-beta-dependent cardiac and skeletal muscle fibrosis by inactivating the SMAD2/3 transcription factors. J Cell Sci. 2019 Aug 8;132(15):jcs234948 |
Als2 alsin Rho guanine nucleotide exchange factor (Synonyms: 3222402C23Rik, 9430073A21Rik, Als2cr6, Alsin, mKIAA1563) | |
Results | Reference |
1 | J:363271 Devon RS, Schwab C, Topp JD, Orban PC, Yang YZ, Pape TD, Helm JR, Davidson TL, Rogers DA, Gros-Louis F, Rouleau G, Horazdovsky BF, Leavitt BR, Hayden MR, Cross-species characterization of the ALS2 gene and analysis of its pattern of expression in development and adulthood. Neurobiol Dis. 2005 Mar;18(2):243-57 |
Alx1 ALX homeobox 1 (Synonyms: Cart1) | |
Results | Reference |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:84742 Pavlov MI, Sautier JM, Oboeuf M, Asselin A, Berdal A, Chondrogenic differentiation during midfacial development in the mouse: in vivo and in vitro studies. Biol Cell. 2003;95(2):75-86 |
Alx3 aristaless-like homeobox 3 | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1* | J:48587 ten Berge D, Brouwer A, el Bahi S, Guenet JL, Robert B, Meijlink F, Mouse Alx3: an aristaless-like homeobox gene expressed during embryogenesis in ectomesenchyme and lateral plate mesoderm. Dev Biol. 1998 Jul 1;199(1):11-25 |
Alx4 aristaless-like homeobox 4 (Synonyms: Aristaless-like 4) | |
Results | Reference |
1 | J:91667 Antonopoulou I, Mavrogiannis LA, Wilkie AO, Morriss-Kay GM, Alx4 and Msx2 play phenotypically similar and additive roles in skull vault differentiation. J Anat. 2004 Jun;204(6):487-99 |
1 | J:246663 Garg A, Bansal M, Gotoh N, Feng GS, Zhong J, Wang F, Kariminejad A, Brooks S, Zhang X, Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis. PLoS Genet. 2017 Oct;13(10):e1007047 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
1* | J:44699 Qu S, Li L, Wisdom R, Alx-4: cDNA cloning and characterization of a novel paired-type homeodomain protein. Gene. 1997 Dec 12;203(2):217-23 |
Ambn ameloblastin | |
Results | Reference |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
1 | J:176483 Holmes G, Bromage TG, Basilico C, The Sox2 high mobility group transcription factor inhibits mature osteoblast function in transgenic mice. Bone. 2011 Oct;49(4):653-61 |
2 | J:188148 Landin MA, Shabestari M, Babaie E, Reseland JE, Osmundsen H, Gene Expression Profiling during Murine Tooth Development. Front Genet. 2012;3:139 |
1* | J:193587 Nakagawa E, Zhang L, Kim EJ, Shin JO, Cho SW, Ohshima H, Jung HS, The novel function of Oct3/4 in mouse tooth development. Histochem Cell Biol. 2012 Mar;137(3):367-76 |
1 | J:160264 Nakatomi M, Wang XP, Key D, Lund JJ, Turbe-Doan A, Kist R, Aw A, Chen Y, Maas RL, Peters H, Genetic interactions between Pax9 and Msx1 regulate lip development and several stages of tooth morphogenesis. Dev Biol. 2010 Apr 15;340(2):438-49 |
Amelx amelogenin, X-linked (Synonyms: Amel, Amg, M100888, Rgsc888) | |
Results | Reference |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
1 | J:152420 Denaxa M, Sharpe PT, Pachnis V, The LIM homeodomain transcription factors Lhx6 and Lhx7 are key regulators of mammalian dentition. Dev Biol. 2009 Sep 15;333(2):324-36 |
1 | J:327958 Eliason S, Su D, Pinho F, Sun Z, Zhang Z, Li X, Sweat M, Venugopalan SR, He B, Bustin M, Amendt BA, HMGN2 represses gene transcription via interaction with transcription factors Lef-1 and Pitx2 during amelogenesis. J Biol Chem. 2022 Jul 21;298(9):102295 |
1* | J:146765 Golonzhka O, Metzger D, Bornert JM, Bay BK, Gross MK, Kioussi C, Leid M, Ctip2/Bcl11b controls ameloblast formation during mammalian odontogenesis. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4278-83 |
2* | J:150097 Gruenbaum-Cohen Y, Tucker AS, Haze A, Shilo D, Taylor AL, Shay B, Sharpe PT, Mitsiadis TA, Ornoy A, Blumenfeld A, Deutsch D, Amelogenin in cranio-facial development: the tooth as a model to study the role of amelogenin during embryogenesis. J Exp Zoolog B Mol Dev Evol. 2009 Jul 15;312B(5):445-57 |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1 | J:130572 Klein OD, Lyons DB, Balooch G, Marshall GW, Basson MA, Peterka M, Boran T, Peterkova R, Martin GR, An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development. 2008 Jan;135(2):377-85 |
1 | J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670 |
3 | J:188148 Landin MA, Shabestari M, Babaie E, Reseland JE, Osmundsen H, Gene Expression Profiling during Murine Tooth Development. Front Genet. 2012;3:139 |
1 | J:203117 Li X, Venugopalan SR, Cao H, Pinho FO, Paine ML, Snead ML, Semina EV, Amendt BA, A model for the molecular underpinnings of tooth defects in Axenfeld-Rieger syndrome. Hum Mol Genet. 2014 Jan 1;23(1):194-208 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1* | J:289361 Snead ML, Luo W, Lau EC, Slavkin HC, Spatial- and temporal-restricted pattern for amelogenin gene expression during mouse molar tooth organogenesis. Development. 1988 Sep;104(1):77-85 |
1* | J:39157 Zeichner-David M, Vo H, Tan H, Diekwisch T, Berman B, Thiemann F , Alcocer MD , Hsu P , Wang T , Eyna J , Caton J , Slavkin HC , MacDougall M, Timing of the expression of enamel gene products during mouse tooth development. Int J Dev Biol. 1997 Feb;41(1):27-38 |
Amh anti-Mullerian hormone (Synonyms: MIS, Mullerian inhibiting substance) | |
Results | Reference |
1 | J:275626 Anamthathmakula P, Miryala CSJ, Moreci RS, Kyathanahalli C, Hassan SS, Condon JC, Jeyasuria P, Steroidogenic Factor 1 (Nr5a1) is Required for Sertoli Cell Survival Post Sex Determination. Sci Rep. 2019 Mar 14;9(1):4452 |
1* | J:171630 Bagheri-Fam S, Argentaro A, Svingen T, Combes AN, Sinclair AH, Koopman P, Harley VR, Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome. Hum Mol Genet. 2011 Jun 1;20(11):2213-24 |
1 | J:134687 Chang H, Gao F, Guillou F, Taketo MM, Huff V, Behringer RR, Wt1 negatively regulates {beta}-catenin signaling during testis development. Development. 2008 May;135(10):1875-85 |
1* | J:166517 Chen G, Yang L, Begum S, Xu L, GPR56 is essential for testis development and male fertility in mice. Dev Dyn. 2010 Dec;239(12):3358-67 |
1 | J:334094 Gu X, Heinrich A, Li SY, DeFalco T, Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions. Nat Commun. 2023 Mar 15;14(1):1439 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:188056 Jameson SA, Lin YT, Capel B, Testis development requires the repression of Wnt4 by Fgf signaling. Dev Biol. 2012 Oct 1;370(1):24-32 |
1 | J:91352 Jeyasuria P, Ikeda Y, Jamin SP, Zhao L, De Rooij DG, Themmen AP, Behringer RR, Parker KL, Cell-specific knockout of steroidogenic factor 1 reveals its essential roles in gonadal function. Mol Endocrinol. 2004 Jul;18(7):1610-9 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
2* | J:297658 Kulibin AY, Malolina EA, Formation of the rete testis during mouse embryonic development. Dev Dyn. 2020 Aug 27; |
1 | J:194924 Lavery R, Chassot AA, Pauper E, Gregoire EP, Klopfenstein M, de Rooij DG, Mark M, Schedl A, Ghyselinck NB, Chaboissier MC, Testicular differentiation occurs in absence of R-spondin1 and Sox9 in mouse sex reversals. PLoS Genet. 2012;8(12):e1003170 |
1* | J:21125 Lee CH, Taketo T, Normal onset, but prolonged expression, of Sry gene in the B6.YDOM sex-reversed mouse gonad. Dev Biol. 1994 Oct;165(2):442-52 |
1 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
1 | J:246806 Li Y, Zhang L, Hu Y, Chen M, Han F, Qin Y, Chen M, Cui X, Duo S, Tang F, Gao F, beta-Catenin directs the transformation of testis Sertoli cells to ovarian granulosa-like cells by inducing Foxl2 expression. J Biol Chem. 2017 Oct 27;292(43):17577-17586 |
1 | J:273473 McKey J, Bunce C, Batchvarov IS, Ornitz DM, Capel B, Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5570-5575 |
1 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1* | J:19486 Munsterberg A, Lovell-Badge R, Expression of the mouse anti-mullerian hormone gene suggests a role in both male and female sexual differentiation. Development. 1991 Oct;113(2):613-24 |
1 | J:269319 Nicol B, Grimm SA, Gruzdev A, Scott GJ, Ray MK, Yao HH, Genome-wide identification of FOXL2 binding and characterization of FOXL2 feminizing action in the fetal gonads. Hum Mol Genet. 2018 Dec 15;27(24):4273-4287 |
1* | J:137610 Nimura M, Udagawa J, Otani H, Adrenocorticotropic hormone affects nonapoptotic cell death of undifferentiated germ cells in the fetal mouse testis: in vivo study by exo utero transplantation of corticotropic tumor cells into embryos. Congenit Anom (Kyoto). 2008 Jun;48(2):81-6 |
1 | J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34 |
1* | J:72502 Perez-Armendariz EM, Lamoyi E, Mason JI, Cisneros-Armas D, Luu-The V, Bravo Moreno JF, Developmental regulation of connexin 43 expression in fetal mouse testicular cells. Anat Rec. 2001 Nov 1;264(3):237-46 |
1 | J:197599 Pitetti JL, Calvel P, Romero Y, Conne B, Truong V, Papaioannou MD, Schaad O, Docquier M, Herrera PL, Wilhelm D, Nef S, Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice. PLoS Genet. 2013;9(1):e1003160 |
2* | J:231047 Rios-Rojas C, Spiller C, Bowles J, Koopman P, Germ cells influence cord formation and leydig cell gene expression during mouse testis development. Dev Dyn. 2016 Apr;245(4):433-44 |
1* | J:76138 Vidal VP, Chaboissier MC, de Rooij DG, Schedl A, Sox9 induces testis development in XX transgenic mice. Nat Genet. 2001 Jul;28(3):216-7 |
1* | J:96928 Wilson MJ, Jeyasuria P, Parker KL, Koopman P, The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development. J Biol Chem. 2005 Feb 18;280(7):5917-23 |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
1 | J:220734 Zhang L, Chen M, Wen Q, Li Y, Wang Y, Wang Y, Qin Y, Cui X, Yang L, Huff V, Gao F, Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4003-8 |
Amhr2 anti-Mullerian hormone type 2 receptor (Synonyms: MISIIR, MIS TypeII receptor) | |
Results | Reference |
1* | J:137806 Arango NA, Kobayashi A, Wang Y, Jamin SP, Lee HH, Orvis GD, Behringer RR, A mesenchymal perspective of Mullerian duct differentiation and regression in Amhr2-lacZ mice. Mol Reprod Dev. 2008 Jul;75(7):1154-62 |
1 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
Amigo1 adhesion molecule with Ig like domain 1 | |
Results | Reference |
2 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Amn amnionless (Synonyms: 5033428N14Rik) | |
Results | Reference |
1 | J:98337 Strope S, Rivi R, Metzger T, Manova K, Lacy E, Mouse amnionless, which is required for primitive streak assembly, mediates cell-surface localization and endocytic function of cubilin on visceral endoderm and kidney proximal tubules. Development. 2004 Oct;131(19):4787-95 |
Amot angiomotin (Synonyms: D0Kist1, E230009N18Rik, mKIAA1071, Sii6) | |
Results | Reference |
1 | J:243807 Ragni CV, Diguet N, Le Garrec JF, Novotova M, Resende TP, Pop S, Charon N, Guillemot L, Kitasato L, Badouel C, Dufour A, Olivo-Marin JC, Trouve A, McNeill H, Meilhac SM, Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth. Nat Commun. 2017 Feb 27;8:14582 |
Amotl1 angiomotin-like 1 (Synonyms: 2310010G08Rik, 2310067L22Rik, 4932416D09Rik, JEAP) | |
Results | Reference |
1 | J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005 |
1 | J:243807 Ragni CV, Diguet N, Le Garrec JF, Novotova M, Resende TP, Pop S, Charon N, Guillemot L, Kitasato L, Badouel C, Dufour A, Olivo-Marin JC, Trouve A, McNeill H, Meilhac SM, Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth. Nat Commun. 2017 Feb 27;8:14582 |
Amotl2 angiomotin-like 2 (Synonyms: Lccp, MASCOT, mKIAA0989) | |
Results | Reference |
1 | J:243807 Ragni CV, Diguet N, Le Garrec JF, Novotova M, Resende TP, Pop S, Charon N, Guillemot L, Kitasato L, Badouel C, Dufour A, Olivo-Marin JC, Trouve A, McNeill H, Meilhac SM, Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth. Nat Commun. 2017 Feb 27;8:14582 |
Ampd3 adenosine monophosphate deaminase 3 | |
Results | Reference |
1* | J:267655 Marjonen H, Toivonen M, Lahti L, Kaminen-Ahola N, Early prenatal alcohol exposure alters imprinted gene expression in placenta and embryo in a mouse model. PLoS One. 2018;13(5):e0197461 |
Amy amylase complex | |
Results | Reference |
1 | J:219809 Afelik S, Pool B, Schmerr M, Penton C, Jensen J, Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development. Dev Biol. 2015 Mar 15;399(2):204-17 |
1 | J:305792 Ansarullah, Jain C, Far FF, Homberg S, Wissmiller K, von Hahn FG, Raducanu A, Schirge S, Sterr M, Bilekova S, Siehler J, Wiener J, Oppenlander L, Morshedi A, Bastidas-Ponce A, Collden G, Irmler M, Beckers J, Feuchtinger A, Grzybek M, Ahlbrecht C, Feederle R, Plettenburg O, Muller TD, Meier M, Tschop MH, Coskun U, Lickert H, Inceptor counteracts insulin signalling in beta-cells to control glycaemia. Nature. 2021 Feb;590(7845):326-331 |
1 | J:119565 Boyer DF, Fujitani Y, Gannon M, Powers AC, Stein RW, Wright CV, Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression. Dev Biol. 2006 Oct 15;298(2):616-31 |
1 | J:307544 Burtscher I, Tarquis-Medina M, Salinno C, Schirge S, Beckenbauer J, Bakhti M, Lickert H, Generation of a Novel Nkx6-1 Venus Fusion Reporter Mouse Line. Int J Mol Sci. 2021 Mar 26;22(7) |
1 | J:129103 Chao CS, Loomis ZL, Lee JE, Sussel L, Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells. Dev Biol. 2007 Dec 15;312(2):523-32 |
1 | J:278248 Chen C, Shiota C, Agostinelli G, Ridley D, Jiang Y, Ma J, Prasadan K, Xiao X, Gittes GK, Evidence of a developmental origin for beta-cell heterogeneity using a dual lineage-tracing technology. Development. 2019 Jun 27;146(13):dev164913 |
1 | J:105207 Chu K, Tsai MJ, Neuronatin, a downstream target of BETA2/NeuroD1 in the pancreas, is involved in glucose-mediated insulin secretion. Diabetes. 2005 Apr;54(4):1064-73 |
1* | J:30445 De Lisle RC, Isom KS, Expression of sulfated gp300 and changes in glycosylation during pancreatic development. J Histochem Cytochem. 1996 Jan;44(1):57-66 |
1 | J:220324 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C, Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 1;142(5):871-82 |
1 | J:119284 Decker K, Goldman DC, Grasch CL, Sussel L, Gata6 is an important regulator of mouse pancreas development. Dev Biol. 2006 Oct 15;298(2):415-29 |
1 | J:119914 Doyle MJ, Loomis ZL, Sussel L, Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet. Development. 2007 Feb;134(3):515-23 |
1 | J:104222 Fazio EN, Everest M, Colman R, Wang R, Pin CL, Altered Glut-2 accumulation and beta-cell function in mice lacking the exocrine-specific transcription factor, Mist1. J Endocrinol. 2005 Dec;187(3):407-18 |
1 | J:168727 Furuyama K, Kawaguchi Y, Akiyama H, Horiguchi M, Kodama S, Kuhara T, Hosokawa S, Elbahrawy A, Soeda T, Koizumi M, Masui T, Kawaguchi M, Takaori K, Doi R, Nishi E, Kakinoki R, Deng JM, Behringer RR, Nakamura T, Uemoto S, Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet. 2011 Jan;43(1):34-41 |
1 | J:192856 George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE, Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol. 2012 Dec;32(24):5116-28 |
2* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1* | J:22553 Guz Y, Montminy MR, Stein R, Leonard J, Gamer LW, Wright CV, Teitelman G, Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny. Development. 1995 Jan;121(1):11-8 |
1* | J:90459 Johnson CL, Kowalik AS, Rajakumar N, Pin CL, Mist1 is necessary for the establishment of granule organization in serous exocrine cells of the gastrointestinal tract. Mech Dev. 2004 Mar;121(3):261-72 |
1 | J:154990 Kang HS, Kim YS, ZeRuth G, Beak JY, Gerrish K, Kilic G, Sosa-Pineda B, Jensen J, Foley J, Jetten AM, Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression. Mol Cell Biol. 2009 Dec;29(24):6366-79 |
1 | J:257425 Kim DS, Song L, Wang J, Wu H, Gu G, Sugi Y, Li Z, Wang H, GRP94 Is an Essential Regulator of Pancreatic beta-Cell Development, Mass, and Function in Male Mice. Endocrinology. 2018 Feb 1;159(2):1062-1073 |
1 | J:250031 Kodama S, Nakano Y, Hirata K, Furuyama K, Horiguchi M, Kuhara T, Masui T, Kawaguchi M, Gannon M, Wright CV, Uemoto S, Kawaguchi Y, Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice. Sci Rep. 2016 Feb 18;6:21211 |
1 | J:230332 Nakano Y, Negishi N, Gocho S, Mine T, Sakurai Y, Yazawa M, Abe K, Yagita H, Habu S, Kageyama R, Kawaguchi Y, Hozumi K, Disappearance of centroacinar cells in the Notch ligand-deficient pancreas. Genes Cells. 2015 Jun;20(6):500-11 |
1 | J:253982 Norlin S, Parekh V, Edlund H, The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival. Development. 2018 Jan 3;145(1):dev154468 |
1* | J:32017 Offield MF, Jetton TL, Labosky PA, Ray M, Stein RW, Magnuson MA, Hogan BL, Wright CV, PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development. 1996 Mar;122(3):983-95 |
1 | J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461 |
2* | J:50645 Petrucco S, Wellauer PK, Hagenbuchle O, The DNA-binding activity of transcription factor PTF1 parallels the synthesis of pancreas-specific mRNAs during mouse development. Mol Cell Biol. 1990 Jan;10(1):254-64 |
1 | J:191071 Petzold KM, Naumann H, Spagnoli FM, Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas. Development. 2013 Jan 1;140(1):126-35 |
1* | J:87397 Sumazaki R, Shiojiri N, Isoyama S, Masu M, Keino-Masu K, Osawa M, Nakauchi H, Kageyama R, Matsui A, Conversion of biliary system to pancreatic tissue in Hes1-deficient mice. Nat Genet. 2004 Jan;36(1):83-7 |
1 | J:147764 Svensson P, Bergqvist I, Norlin S, Edlund H, MFng is dispensable for mouse pancreas development and function. Mol Cell Biol. 2009 Apr;29(8):2129-38 |
1 | J:307817 Theis A, Singer RA, Garofalo D, Paul A, Narayana A, Sussel L, Groucho co-repressor proteins regulate beta cell development and proliferation by repressing Foxa1 in the developing mouse pancreas. Development. 2021 Mar 24;148(6):dev192401 |
1 | J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521 |
1 | J:119908 Wells JM, Esni F, Boivin GP, Aronow BJ, Stuart W, Combs C, Sklenka A, Leach SD, Lowy AM, Wnt/beta-catenin signaling is required for development of the exocrine pancreas. BMC Dev Biol. 2007;7:4 |
Ang angiogenin, ribonuclease, RNase A family, 5 (Synonyms: Ang1, Rnase5a) | |
Results | Reference |
1 | J:124714 Subramanian V, Feng Y, A new role for angiogenin in neurite growth and pathfinding: implications for amyotrophic lateral sclerosis. Hum Mol Genet. 2007 Jun 15;16(12):1445-53 |
Ang2 angiogenin, ribonuclease A family, member 2 (Synonyms: Angrp, Rnase5b) | |
Results | Reference |
2* | J:185336 Marteau L, Pacary E, Valable S, Bernaudin M, Guillemot F, Petit E, Angiopoietin-2 regulates cortical neurogenesis in the developing telencephalon. Cereb Cortex. 2011 Jul;21(7):1695-702 |
Angpt1 angiopoietin 1 (Synonyms: 1110046O21Rik, ang1, Ang-1, Angiopoietin-1) | |
Results | Reference |
1 | J:311143 Courtney JA, Wilson RL, Cnota J, Jones HN, Conditional Mutation of Hand1 in the Mouse Placenta Disrupts Placental Vascular Development Resulting in Fetal Loss in Both Early and Late Pregnancy. Int J Mol Sci. 2021 Sep 2;22(17) |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1 | J:185218 Hall-Glenn F, De Young RA, Huang BL, van Handel B, Hofmann JJ, Chen TT, Choi A, Ong JR, Benya PD, Mikkola H, Iruela-Arispe ML, Lyons KM, CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PLoS One. 2012;7(2):e30562 |
1 | J:339841 Liu P, Lavine JA, Fawzi A, Quaggin SE, Thomson BR, Angiopoietin-1 Is Required for Vortex Vein and Choriocapillaris Development in Mice. Arterioscler Thromb Vasc Biol. 2022 Nov;42(11):1413-1427 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1* | J:57001 Yuan HT, Suri C, Yancopoulos GD, Woolf AS, Expression of angiopoietin-1, angiopoietin-2, and the Tie-2 receptor tyrosine kinase during mouse kidney maturation. J Am Soc Nephrol. 1999 Aug;10(8):1722-36 |
Angpt2 angiopoietin 2 (Synonyms: Ang-2, Ang2) | |
Results | Reference |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:145448 Shimoda H, Immunohistochemical demonstration of Angiopoietin-2 in lymphatic vascular development. Histochem Cell Biol. 2009 Feb;131(2):231-8 |
1 | J:346785 Wang S, Zhang H, Wiltshire T, Sealock R, Faber JE, Genetic dissection of the Canq1 locus governing variation in extent of the collateral circulation. PLoS One. 2012;7(3):e31910 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1* | J:57001 Yuan HT, Suri C, Yancopoulos GD, Woolf AS, Expression of angiopoietin-1, angiopoietin-2, and the Tie-2 receptor tyrosine kinase during mouse kidney maturation. J Am Soc Nephrol. 1999 Aug;10(8):1722-36 |
Angptl3 angiopoietin-like 3 (Synonyms: hypl) | |
Results | Reference |
1* | J:159378 Chou S, Lodish HF, Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7799-804 |
Angptl4 angiopoietin-like 4 (Synonyms: BK89, FIAF, HFARP, NG27) | |
Results | Reference |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
Ank progressive ankylosis (Synonyms: D15Ertd221e, mKIAA1581) | |
Results | Reference |
1 | J:276880 Motch Perrine SM, Wu M, Stephens NB, Kriti D, van Bakel H, Jabs EW, Richtsmeier JT, Mandibular dysmorphology due to abnormal embryonic osteogenesis in FGFR2-related craniosynostosis mice. Dis Model Mech. 2019 May 30;12(5):dmm038513 |
Ank2 ankyrin 2, brain (Synonyms: Ank-2, Ankyrin-2, ankyrin B, Ankyrin-B, Gm4392) | |
Results | Reference |
1* | J:324233 Kawano S, Baba M, Fukushima H, Miura D, Hashimoto H, Nakazawa T, Autism-associated ANK2 regulates embryonic neurodevelopment. Biochem Biophys Res Commun. 2022 May 21;605:45-50 |
Ank3 ankyrin 3, epithelial (Synonyms: 2900054D09Rik, Ank-3, AnkG, Ankyrin-3, Ankyrin-G) | |
Results | Reference |
1 | J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82 |
1 | J:231960 Freal A, Fassier C, Le Bras B, Bullier E, De Gois S, Hazan J, Hoogenraad CC, Couraud F, Cooperative Interactions between 480 kDa Ankyrin-G and EB Proteins Assemble the Axon Initial Segment. J Neurosci. 2016 Apr 20;36(16):4421-33 |
2* | J:214712 Le Bras B, Freal A, Czarnecki A, Legendre P, Bullier E, Komada M, Brophy PJ, Davenne M, Couraud F, In vivo assembly of the axon initial segment in motor neurons. Brain Struct Funct. 2014 Jul;219(4):1433-50 |
1 | J:270142 Rasiah PK, Maddala R, Bennett V, Rao PV, Ankyrin-G regulated epithelial phenotype is required for mouse lens morphogenesis and growth. Dev Biol. 2019 Feb 1;446(1):119-131 |
Ankfn1 ankyrin-repeat and fibronectin type III domain containing 1 (Synonyms: 4932411E22Rik, LOC382543, mWAKE, nmf9) | |
Results | Reference |
1 | J:221935 Zhang S, Ross KD, Seidner GA, Gorman MR, Poon TH, Wang X, Keithley EM, Lee PN, Martindale MQ, Joiner WJ, Hamilton BA, Nmf9 Encodes a Highly Conserved Protein Important to Neurological Function in Mice and Flies. PLoS Genet. 2015 Jul;11(7):e1005344 |
Ankfy1 ankyrin repeat and FYVE domain containing 1 (Synonyms: Ankhzn, mKIAA1255) | |
Results | Reference |
3* | J:54189 Ito K, Ishii N, Miyashita A, Tominaga K, Kuriyama H, Maruyama H, Shirai M, Naito M, Arakawa M, Kuwano R, Molecular cloning of a novel 130-kDa cytoplasmic protein, Ankhzn, containing Ankyrin repeats hooked to a zinc finger motif. Biochem Biophys Res Commun. 1999 Apr 2;257(1):206-13 |
Ankrd1 ankyrin repeat domain 1 (Synonyms: Alrp, CARP, Crap, MARP1) | |
Results | Reference |
1* | J:302851 Greschik H, Duteil D, Messaddeq N, Willmann D, Arrigoni L, Sum M, Jung M, Metzger D, Manke T, Gunther T, Schule R, The histone code reader Spin1 controls skeletal muscle development. Cell Death Dis. 2017 Nov 23;8(11):e3173 |
1* | J:42751 Jeyaseelan R, Poizat C, Baker RK, Abdishoo S, Isterabadi LB, Lyons GE , Kedes L, A novel cardiac-restricted target for doxorubicin. CARP, a nuclear modulator of gene expression in cardiac progenitor cells and cardiomyocytes. J Biol Chem. 1997 Sep 5;272(36):22800-8 |
Ankrd2 ankyrin repeat domain 2 (Synonyms: Arpp, mArpp) | |
Results | Reference |
1* | J:302851 Greschik H, Duteil D, Messaddeq N, Willmann D, Arrigoni L, Sum M, Jung M, Metzger D, Manke T, Gunther T, Schule R, The histone code reader Spin1 controls skeletal muscle development. Cell Death Dis. 2017 Nov 23;8(11):e3173 |
Anks1 ankyrin repeat and SAM domain containing 1 (Synonyms: MGC:59413, mKIAA0229, Odin) | |
Results | Reference |
1* | J:290589 Park S, Lee H, Lee J, Park E, Park S, Ependymal Cells Require Anks1a for Their Proper Development. Mol Cells. 2019 Mar 31;42(3):245-251 |
Anln anillin, actin binding protein (Synonyms: 1110037A17Rik, 2900037I21Rik, Scraps) | |
Results | Reference |
1 | J:290729 Grundl M, Walz S, Hauf L, Schwab M, Werner KM, Spahr S, Schulte C, Maric HM, Ade CP, Gaubatz S, Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes. PLoS Genet. 2020 May;16(5):e1008818 |
Ano1 anoctamin 1, calcium activated chloride channel (Synonyms: Tmem16a) | |
Results | Reference |
1 | J:276557 Hong GS, Lee SH, Lee B, Choi JH, Oh SJ, Jang Y, Hwang EM, Kim H, Jung J, Kim IB, Oh U, ANO1/TMEM16A regulates process maturation in radial glial cells in the developing brain. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12494-12499 |
1 | J:237697 Maurya DK, Henriques T, Marini M, Pedemonte N, Galietta LJ, Rock JR, Harfe BD, Menini A, Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice. PLoS One. 2015;10(6):e0129171 |
1* | J:138613 Rock JR, Futtner CR, Harfe BD, The transmembrane protein TMEM16A is required for normal development of the murine trachea. Dev Biol. 2008 Sep 1;321(1):141-9 |
1* | J:138798 Rock JR, Harfe BD, Expression of TMEM16 paralogs during murine embryogenesis. Dev Dyn. 2008 Sep;237(9):2566-74 |
Ano2 anoctamin 2 (Synonyms: MGC:38715, Tmem16b) | |
Results | Reference |
1* | J:138798 Rock JR, Harfe BD, Expression of TMEM16 paralogs during murine embryogenesis. Dev Dyn. 2008 Sep;237(9):2566-74 |
Ano3 anoctamin 3 (Synonyms: B230324K02Rik, Tmem16c) | |
Results | Reference |
1* | J:138798 Rock JR, Harfe BD, Expression of TMEM16 paralogs during murine embryogenesis. Dev Dyn. 2008 Sep;237(9):2566-74 |
Ano6 anoctamin 6 (Synonyms: 2900059G15Rik, F730003B03Rik, Tmem16f) | |
Results | Reference |
1* | J:195901 Ehlen H, Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues. J Bone Miner Res. 2013;28(2):246-59 |
1* | J:138798 Rock JR, Harfe BD, Expression of TMEM16 paralogs during murine embryogenesis. Dev Dyn. 2008 Sep;237(9):2566-74 |
Ano9 anoctamin 9 (Synonyms: 5430425C04Rik, Tmem16j, Tp53i5, Trp53i5) | |
Results | Reference |
1* | J:138798 Rock JR, Harfe BD, Expression of TMEM16 paralogs during murine embryogenesis. Dev Dyn. 2008 Sep;237(9):2566-74 |
Anp32a acidic nuclear phosphoprotein 32 family member A (Synonyms: Anp32, pp32) | |
Results | Reference |
3* | J:315096 Wang S, Wang Y, Lu Q, Liu X, Wang F, Ma X, Cui C, Shi C, Li J, Zhang D, The expression and distributions of ANP32A in the developing brain. Biomed Res Int. 2015;2015:207347 |
Anp32b acidic nuclear phosphoprotein 32 family member B (Synonyms: 2410015B15Rik, PAL31, PHAPI2a) | |
Results | Reference |
1* | J:88220 Amasaki H, Ogawa M, Nagasao J, Mutoh K, Ichihara N, Asari M, Shiota K, Distributional changes of BrdU, PCNA, E2F1 and PAL31 molecules in developing murine palatal rugae. Ann Anat. 2003 Dec;185(6):517-23 |
Anpep alanyl aminopeptidase, membrane (Synonyms: aminopeptidase N, Apn, Cd13) | |
Results | Reference |
1* | J:119474 Rangel R, Sun Y, Guzman-Rojas L, Ozawa MG, Sun J, Giordano RJ, Van Pelt CS, Tinkey PT, Behringer RR, Sidman RL, Arap W, Pasqualini R, Impaired angiogenesis in aminopeptidase N-null mice. Proc Natl Acad Sci U S A. 2007 Mar 13;104(11):4588-93 |
Anxa1 annexin A1 (Synonyms: Anx-1, Anx-A1, C430014K04Rik, Lpc-1, Lpc1) | |
Results | Reference |
1 | J:271268 Yui S, Azzolin L, Maimets M, Pedersen MT, Fordham RP, Hansen SL, Larsen HL, Guiu J, Alves MRP, Rundsten CF, Johansen JV, Li Y, Madsen CD, Nakamura T, Watanabe M, Nielsen OH, Schweiger PJ, Piccolo S, Jensen KB, YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration. Cell Stem Cell. 2018 Jan 4;22(1):35-49.e7 |
Anxa5 annexin A5 (Synonyms: annexin V, Anx5) | |
Results | Reference |
1 | J:170178 Kobayashi K, Umezawa K, Yasui M, Apoptosis in mouse amniotic epithelium is induced by activated macrophages through the TNF receptor type 1/TNF pathway. Biol Reprod. 2011 Feb;84(2):248-54 |
1 | J:191589 Nishimura R, Wakabayashi M, Hata K, Matsubara T, Honma S, Wakisaka S, Kiyonari H, Shioi G, Yamaguchi A, Tsumaki N, Akiyama H, Yoneda T, Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification. J Biol Chem. 2012 Sep 28;287(40):33179-90 |
Anxa7 annexin A7 (Synonyms: Anx7, synexin) | |
Results | Reference |
1 | J:98558 Rick M, Ramos Garrido SI, Herr C, Thal DR, Noegel AA, Clemen CS, Nuclear localization of Annexin A7 during murine brain development. BMC Neurosci. 2005 Apr 10;6(1):25 |
Anxa11 annexin A11 (Synonyms: A830099O17Rik, Anx11) | |
Results | Reference |
2* | J:101007 Williams LH, McClive PJ, Van Den Bergen JA, Sinclair AH, Annexin XI co-localises with calcyclin in proliferating cells of the embryonic mouse testis. Dev Dyn. 2005 Oct;234(2):432-7 |
Ap1s2 adaptor-related protein complex 1, sigma 2 subunit (Synonyms: 1500012A13Rik, EST1) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Ap4m1 adaptor-related protein complex AP-4, mu 1 (Synonyms: 4930443L05Rik) | |
Results | Reference |
1* | J:154242 Verkerk AJ, Schot R, Dumee B, Schellekens K, Swagemakers S, Bertoli-Avella AM, Lequin MH, Dudink J, Govaert P, van Zwol AL, Hirst J, Wessels MW, Catsman-Berrevoets C, Verheijen FW, de Graaff E, de Coo IF, Kros JM, Willemsen R, Willems PJ, van der Spek PJ, Mancini GM, Mutation in the AP4M1 gene provides a model for neuroaxonal injury in cerebral palsy. Am J Hum Genet. 2009 Jul;85(1):40-52 |
Apbb2 amyloid beta precursor protein binding family B member 2 (Synonyms: 2310007D03Rik, FE65L1, Rirl1, TR2L, Zfra) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Apc APC, WNT signaling pathway regulator (Synonyms: adenomatosis polyposis coli, CC1, Min) | |
Results | Reference |
1 | J:311814 Eom TY, Stanco A, Guo J, Wilkins G, Deslauriers D, Yan J, Monckton C, Blair J, Oon E, Perez A, Salas E, Oh A, Ghukasyan V, Snider WD, Rubenstein JL, Anton ES, Differential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration. Dev Cell. 2014 Dec 22;31(6):677-89 |
1 | J:162871 Li A, Xing Y, Chan B, Heisterkamp N, Groffen J, Borok Z, Minoo P, Li C, Cell type-specific expression of adenomatous polyposis coli in lung development, injury, and repair. Dev Dyn. 2010 Aug;239(8):2288-97 |
Apc2 APC regulator of WNT signaling pathway 2 (Synonyms: APCL) | |
Results | Reference |
1 | J:184856 Shintani T, Takeuchi Y, Fujikawa A, Noda M, Directional neuronal migration is impaired in mice lacking adenomatous polyposis coli 2. J Neurosci. 2012 May 9;32(19):6468-84 |
Apcdd1 adenomatosis polyposis coli down-regulated 1 (Synonyms: Drapc1, EIG180) | |
Results | Reference |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1 | J:338889 Siguero-Alvarez M, Salguero-Jimenez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sanchez-Saez F, Pineiro-Sabaris R, Felipe-Medina N, Torroja C, Gomez MJ, Sabater-Molina M, Escriba R, Richaud-Patin I, Iglesias-Garcia O, Sbroggio M, Callejas S, O'Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibanez B, Monserrat L, Perez-Pomares JM, Sanchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL, A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation. 2023 Jan 3;147(1):47-65 |
Apln apelin (Synonyms: 6030430G11Rik) | |
Results | Reference |
1 | J:297312 Gillich A, Zhang F, Farmer CG, Travaglini KJ, Tan SY, Gu M, Zhou B, Feinstein JA, Krasnow MA, Metzger RJ, Capillary cell-type specialization in the alveolus. Nature. 2020 Oct;586(7831):785-789 |
Aplnr apelin receptor (Synonyms: Agtrl1, apelin receptor, APJ, msr/apj) | |
Results | Reference |
1 | J:239279 Kidoya H, Naito H, Muramatsu F, Yamakawa D, Jia W, Ikawa M, Sonobe T, Tsuchimochi H, Shirai M, Adams RH, Fukamizu A, Takakura N, APJ Regulates Parallel Alignment of Arteries and Veins in the Skin. Dev Cell. 2015 May 04;33(3):247-59 |
1 | J:317975 Lu P, Wang Y, Liu Y, Wang Y, Wu B, Zheng D, Harvey RP, Zhou B, Perinatal angiogenesis from pre-existing coronary vessels via DLL4-NOTCH1 signalling. Nat Cell Biol. 2021 Sep;23(9):967-977 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
Aplp1 amyloid beta precursor like protein 1 | |
Results | Reference |
1* | J:167050 Khan QE, Press CM, Sehic A, Landin MA, Risnes S, Osmundsen H, Expression of prion gene and presence of prion protein during development of mouse molar tooth germ. Eur J Oral Sci. 2010 Dec;118(6):559-65 |
Apoa1 apolipoprotein A-I (Synonyms: Alp-1, Apoa-1, Brp-14, Ltw-1, Lvtw-1, Sep-1, Sep-2, Sep2) | |
Results | Reference |
1* | J:175686 Cote M, Provost PR, Tremblay Y, Apolipoprotein A-I, A-II, and H mRNA and protein accumulation sites in the developing lung in late gestation. BMC Res Notes. 2011;4:235 |
1* | J:311215 Fazilaty H, Brugger MD, Valenta T, Szczerba BM, Berkova L, Doumpas N, Hausmann G, Scharl M, Basler K, Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage. Cell Rep. 2021 Aug 3;36(5):109484 |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
1* | J:145715 Provost PR, Boucher E, Tremblay Y, Apolipoprotein A-I, A-II, C-II, and H expression in the developing lung and sex difference in surfactant lipids. J Endocrinol. 2009 Mar;200(3):321-30 |
Apoa2 apolipoprotein A-II (Synonyms: Alp-2, Apoa-2, ApoA-II, Hdl-1) | |
Results | Reference |
1* | J:175686 Cote M, Provost PR, Tremblay Y, Apolipoprotein A-I, A-II, and H mRNA and protein accumulation sites in the developing lung in late gestation. BMC Res Notes. 2011;4:235 |
1* | J:145715 Provost PR, Boucher E, Tremblay Y, Apolipoprotein A-I, A-II, C-II, and H expression in the developing lung and sex difference in surfactant lipids. J Endocrinol. 2009 Mar;200(3):321-30 |
Apoa4 apolipoprotein A-IV (Synonyms: Apoa-4) | |
Results | Reference |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
Apob apolipoprotein B (Synonyms: apob-100, apob-48) | |
Results | Reference |
1 | J:202649 Evangelisti C, Bianco F, Pradella LM, Puliti A, Goldoni A, Sbrana I, Rossi M, Vargiolu M, Seri M, Romeo G, Stanghellini V, de Giorgio R, Bonora E, Apolipoprotein B is a new target of the GDNF/RET and ET-3/EDNRB signalling pathways. Neurogastroenterol Motil. 2012 Oct;24(10):e497-508 |
Apoc2 apolipoprotein C2 | |
Results | Reference |
2* | J:166893 Cote M, Provost PR, Gerard-Hudon MC, Tremblay Y, Apolipoprotein C-II and lipoprotein lipase show a temporal and geographic correlation with surfactant lipid synthesis in preparation for birth. BMC Dev Biol. 2010;10:111 |
1* | J:145715 Provost PR, Boucher E, Tremblay Y, Apolipoprotein A-I, A-II, C-II, and H expression in the developing lung and sex difference in surfactant lipids. J Endocrinol. 2009 Mar;200(3):321-30 |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
Apoc3 apolipoprotein C-III | |
Results | Reference |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
Apod apolipoprotein D | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Apoe apolipoprotein E | |
Results | Reference |
1 | J:56214 Bachner D, Schroder D, Betat N, Ahrens M, Gross G, Apolipoprotein E (ApoE), a Bmp-2 (bone morphogenetic protein) upregulated gene in mesenchymal progenitors (C3H10T1/2), is highly expressed in murine embryonic development. Biofactors. 1999;9(1):11-7 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:274409 Masuda T, Sankowski R, Staszewski O, Bottcher C, Amann L, Sagar, Scheiwe C, Nessler S, Kunz P, van Loo G, Coenen VA, Reinacher PC, Michel A, Sure U, Gold R, Grun D, Priller J, Stadelmann C, Prinz M, Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution. Nature. 2019 Feb;566(7744):388-392 |
1* | J:145715 Provost PR, Boucher E, Tremblay Y, Apolipoprotein A-I, A-II, C-II, and H expression in the developing lung and sex difference in surfactant lipids. J Endocrinol. 2009 Mar;200(3):321-30 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Apoh apolipoprotein H (Synonyms: B2GPI, beta-2-glycoprotein 1, beta-2-GPI) | |
Results | Reference |
2* | J:175686 Cote M, Provost PR, Tremblay Y, Apolipoprotein A-I, A-II, and H mRNA and protein accumulation sites in the developing lung in late gestation. BMC Res Notes. 2011;4:235 |
1* | J:145715 Provost PR, Boucher E, Tremblay Y, Apolipoprotein A-I, A-II, C-II, and H expression in the developing lung and sex difference in surfactant lipids. J Endocrinol. 2009 Mar;200(3):321-30 |
Apom apolipoprotein M (Synonyms: 1190010O19Rik, G3a, NG20) | |
Results | Reference |
1* | J:91323 Zhang XY, Jiao GQ, Hurtig M, Dong X, Zheng L, Luo GH, Nilsson-Ehle P, Ye Q, Xu N, Expression pattern of apolipoprotein M during mouse and human embryogenesis. Acta Histochem. 2004;106(2):123-8 |
App amyloid beta precursor protein (Synonyms: Abeta, Adap, appican, betaAPP, Cvap, E030013M08Rik, protease nexin II) | |
Results | Reference |
3 | J:63791 Akaaboune M, Allinquant B, Farza H, Roy K, Magoul R, Fiszman M, Festoff BW, Hantai D, Developmental regulation of amyloid precursor protein at the neuromuscular junction in mouse skeletal muscle. Mol Cell Neurosci. 2000 Apr;15(4):355-67 |
1 | J:188237 Liu W, Liu C, Zhu J, Shu P, Yin B, Gong Y, Qiang B, Yuan J, Peng X, MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice. Neurobiol Aging. 2012 Mar;33(3):522-34 |
2 | J:95286 Lopez-Sanchez N, Muller U, Frade JM, Lengthening of G2/mitosis in cortical precursors from mice lacking beta-amyloid precursor protein. Neuroscience. 2005;130(1):51-60 |
1 | J:152457 Wang Z, Wang B, Yang L, Guo Q, Aithmitti N, Songyang Z, Zheng H, Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. J Neurosci. 2009 Sep 2;29(35):10788-801 |
Aqp1 aquaporin 1 (Synonyms: CHIP28) | |
Results | Reference |
1 | J:183431 Aboudehen K, Hilliard S, Saifudeen Z, El-Dahr SS, Mechanisms of p53 activation and physiological relevance in the developing kidney. Am J Physiol Renal Physiol. 2012 Apr;302(8):F928-40 |
1 | J:202949 Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J, Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18042-51 |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
1 | J:304642 Dupacova N, Antosova B, Paces J, Kozmik Z, Meis homeobox genes control progenitor competence in the retina. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2013136118 |
1 | J:152851 Huang X, Ketova T, Fleming JT, Wang H, Dey SK, Litingtung Y, Chiang C, Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus. Development. 2009 Aug;136(15):2535-43 |
1 | J:102995 Johansson PA, Dziegielewska KM, Ek CJ, Habgood MD, Mollgard K, Potter A, Schuliga M, Saunders NR, Aquaporin-1 in the choroid plexuses of developing mammalian brain. Cell Tissue Res. 2005 Dec;322(3):353-64 |
1 | J:184011 John A, Brylka H, Wiegreffe C, Simon R, Liu P, Juttner R, Crenshaw EB 3rd, Luyten FP, Jenkins NA, Copeland NG, Birchmeier C, Britsch S, Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. Development. 2012 May;139(10):1831-41 |
2 | J:154841 Jouret F, Igarashi T, Gofflot F, Wilson PD, Karet FE, Thakker RV, Devuyst O, Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5. Kidney Int. 2004 Jan;65(1):198-208 |
1 | J:273296 Kaiser K, Gyllborg D, Prochazka J, Salasova A, Kompanikova P, Molina FL, Laguna-Goya R, Radaszkiewicz T, Harnos J, Prochazkova M, Potesil D, Barker RA, Casado AG, Zdrahal Z, Sedlacek R, Arenas E, Villaescusa JC, Bryja V, WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis. Nat Commun. 2019 Apr 2;10(1):1498 |
1 | J:308827 Kaiser K, Jang A, Kompanikova P, Lun MP, Prochazka J, Machon O, Dani N, Prochazkova M, Laurent B, Gyllborg D, van Amerongen R, Fame RM, Gupta S, Wu F, Barker RA, Bukova I, Sedlacek R, Kozmik Z, Arenas E, Lehtinen MK, Bryja V, MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus. Development. 2021 May 15;148(10):dev192054 |
1 | J:167016 Kobayashi K, Yasui M, Cellular and subcellular localization of aquaporins 1, 3, 8, and 9 in amniotic membranes during pregnancy in mice. Cell Tissue Res. 2010 Nov;342(2):307-16 |
1 | J:257613 Kuony A, Michon F, Epithelial Markers aSMA, Krt14, and Krt19 Unveil Elements of Murine Lacrimal Gland Morphogenesis and Maturation. Front Physiol. 2017;8:739 |
2* | J:160026 Larsen HS, Ruus AK, Galtung HK, Aquaporin expression patterns in the developing mouse salivary gland. Eur J Oral Sci. 2009 Dec;117(6):655-62 |
1* | J:346057 Lu D, Zhi Y, Su H, Lin X, Lin J, Shi Y, Yi W, Hong C, Zhang T, Fu Z, Chen LY, Zhao Z, Li R, Xu Z, Chen W, Wang N, Xu D, ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells. Cell Rep. 2024 Feb 24;43(3):113818 |
1* | J:221341 Lun MP, Johnson MB, Broadbelt KG, Watanabe M, Kang YJ, Chau KF, Springel MW, Malesz A, Sousa AM, Pletikos M, Adelita T, Calicchio ML, Zhang Y, Holtzman MJ, Lidov HG, Sestan N, Steen H, Monuki ES, Lehtinen MK, Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production. J Neurosci. 2015 Mar 25;35(12):4903-16 |
2* | J:295950 Luo H, Liu Y, Song Y, Hua Y, Zhu X, Aquaporin 1 affects pregnancy outcome and regulates aquaporin 8 and 9 expressions in the placenta. Cell Tissue Res. 2020 Sep;381(3):543-554 |
2* | J:321244 Luo H, Xie A, Hua Y, Wang J, Liu Y, Zhu X, Aquaporin 1 gene deletion affects the amniotic fluid volume and composition as well as the expression of other aquaporin water channels in placenta and fetal membranes. Clin Chim Acta. 2018 Jul;482:161-165 |
1 | J:353306 Ma YS, Deng SQ, Zhang P, Thomsen JS, Andreasen A, Chang SJ, Zhang J, Gu L, Zhai XY, Identification of countercurrent tubule-vessel arrangements in the early development of mouse kidney based on immunohistochemistry and computer-assisted 3D visualization. PLoS One. 2024;19(8):e0307223 |
1 | J:320719 Parichha A, Suresh V, Chatterjee M, Kshirsagar A, Ben-Reuven L, Olender T, Taketo MM, Radosevic V, Bobic-Rasonja M, Trnski S, Holtzman MJ, Jovanov-Milosevic N, Reiner O, Tole S, Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate. Nat Commun. 2022 Feb 2;13(1):633 |
2* | J:151683 Parreira KS, Debaix H, Cnops Y, Geffers L, Devuyst O, Expression patterns of the aquaporin gene family during renal development: influence of genetic variability. Pflugers Arch. 2009 Aug;458(4):745-59 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:126927 Ruiz-Ederra J, Verkman AS, Aquaporin-1 independent microvessel proliferation in a neonatal mouse model of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4802-10 |
1 | J:153606 Wodarczyk C, Rowe I, Chiaravalli M, Pema M, Qian F, Boletta A, A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus. PLoS One. 2009;4(9):e7137 |
Aqp2 aquaporin 2 | |
Results | Reference |
1 | J:183431 Aboudehen K, Hilliard S, Saifudeen Z, El-Dahr SS, Mechanisms of p53 activation and physiological relevance in the developing kidney. Am J Physiol Renal Physiol. 2012 Apr;302(8):F928-40 |
1 | J:355097 Gao C, Chen L, Chen E, Tsilosani A, Xia Y, Zhang W, Generation of Distal Renal Segments Involves a Unique Population of Aqp2 + Progenitor Cells. J Am Soc Nephrol. 2021 Dec 1;32(12):3035-3049 |
1 | J:241013 Grassmeyer J, Mukherjee M, deRiso J, Hettinger C, Bailey M, Sinha S, Visvader JE, Zhao H, Fogarty E, Surendran K, Elf5 is a principal cell lineage specific transcription factor in the kidney that contributes to Aqp2 and Avpr2 gene expression. Dev Biol. 2017 Apr 01;424(1):77-89 |
1* | J:173795 Hilliard S, Aboudehen K, Yao X, El-Dahr SS, Tight regulation of p53 activity by Mdm2 is required for ureteric bud growth and branching. Dev Biol. 2011 May 15;353(2):354-66 |
1 | J:154589 Jeong HW, Jeon US, Koo BK, Kim WY, Im SK, Shin J, Cho Y, Kim J, Kong YY, Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice. J Clin Invest. 2009 Nov;119(11):3290-300 |
1* | J:150394 Jouret F, Auzanneau C, Debaix H, Wada GH, Pretto C, Marbaix E, Karet FE, Courtoy PJ, Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. J Am Soc Nephrol. 2005 Nov;16(11):3235-46 |
1 | J:333405 Kurtzeborn K, Kwon HN, Iaroshenko V, Faisal I, Ambroz M, Jin X, Qureshi T, Kupari J, Ihermann-Hella A, Vaananen J, Tyynismaa H, Bousova I, Park S, Kuure S, Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of MAPK/ERK targets in embryonic kidney. BMC Biol. 2022 May 13;20(1):112 |
1 | J:353306 Ma YS, Deng SQ, Zhang P, Thomsen JS, Andreasen A, Chang SJ, Zhang J, Gu L, Zhai XY, Identification of countercurrent tubule-vessel arrangements in the early development of mouse kidney based on immunohistochemistry and computer-assisted 3D visualization. PLoS One. 2024;19(8):e0307223 |
2* | J:151683 Parreira KS, Debaix H, Cnops Y, Geffers L, Devuyst O, Expression patterns of the aquaporin gene family during renal development: influence of genetic variability. Pflugers Arch. 2009 Aug;458(4):745-59 |
1 | J:138247 Saburi S, Hester I, Fischer E, Pontoglio M, Eremina V, Gessler M, Quaggin SE, Harrison R, Mount R, McNeill H, Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nat Genet. 2008 Aug;40(8):1010-5 |
1 | J:291675 Zhang P, Gu L, Cong J, Zhang J, Thomsen JS, Andreasen A, Chang SJ, Deng SQ, Xing J, Zhai XY, Morphology of the initial nephron-collecting duct connection in mice using computerized 3D tracing and electron microscopy. Biochem Biophys Res Commun. 2019 Jan 29;509(1):114-118 |
Aqp3 aquaporin 3 | |
Results | Reference |
1 | J:167016 Kobayashi K, Yasui M, Cellular and subcellular localization of aquaporins 1, 3, 8, and 9 in amniotic membranes during pregnancy in mice. Cell Tissue Res. 2010 Nov;342(2):307-16 |
2* | J:160026 Larsen HS, Ruus AK, Galtung HK, Aquaporin expression patterns in the developing mouse salivary gland. Eur J Oral Sci. 2009 Dec;117(6):655-62 |
2* | J:295950 Luo H, Liu Y, Song Y, Hua Y, Zhu X, Aquaporin 1 affects pregnancy outcome and regulates aquaporin 8 and 9 expressions in the placenta. Cell Tissue Res. 2020 Sep;381(3):543-554 |
2* | J:321244 Luo H, Xie A, Hua Y, Wang J, Liu Y, Zhu X, Aquaporin 1 gene deletion affects the amniotic fluid volume and composition as well as the expression of other aquaporin water channels in placenta and fetal membranes. Clin Chim Acta. 2018 Jul;482:161-165 |
2* | J:151683 Parreira KS, Debaix H, Cnops Y, Geffers L, Devuyst O, Expression patterns of the aquaporin gene family during renal development: influence of genetic variability. Pflugers Arch. 2009 Aug;458(4):745-59 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Aqp4 aquaporin 4 (Synonyms: aquaporin-4) | |
Results | Reference |
1 | J:183431 Aboudehen K, Hilliard S, Saifudeen Z, El-Dahr SS, Mechanisms of p53 activation and physiological relevance in the developing kidney. Am J Physiol Renal Physiol. 2012 Apr;302(8):F928-40 |
2* | J:160026 Larsen HS, Ruus AK, Galtung HK, Aquaporin expression patterns in the developing mouse salivary gland. Eur J Oral Sci. 2009 Dec;117(6):655-62 |
1* | J:151683 Parreira KS, Debaix H, Cnops Y, Geffers L, Devuyst O, Expression patterns of the aquaporin gene family during renal development: influence of genetic variability. Pflugers Arch. 2009 Aug;458(4):745-59 |
1 | J:275375 Sun S, Zhu XJ, Huang H, Guo W, Tang T, Xie B, Xu X, Zhang Z, Shen Y, Dai ZM, Qiu M, WNT signaling represses astrogliogenesis via Ngn2-dependent direct suppression of astrocyte gene expression. Glia. 2019 Jul;67(7):1333-1343 |
Aqp5 aquaporin 5 | |
Results | Reference |
2* | J:177204 Aure MH, Larsen HS, Ruus AK, Galtung HK, Aquaporin 5 distribution pattern during development of the mouse sublingual salivary gland. J Mol Histol. 2011 Oct;42(5):401-8 |
2 | J:341713 Aure MH, Symonds JM, Villapudua CU, Dodge JT, Werner S, Knosp WM, Hoffman MP, FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation. Nat Commun. 2023 Oct 14;14(1):6485 |
1 | J:173840 El-Hashash AH, Al Alam D, Turcatel G, Rogers O, Li X, Bellusci S, Warburton D, Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. Dev Biol. 2011 May 15;353(2):242-58 |
2 | J:326201 Hayashi T, Eto K, Kadoya Y, Downregulation of ten-eleven translocation-2 triggers epithelial differentiation during organogenesis. Differentiation. 2022 May-Jun;125:45-53 |
1 | J:150516 Hu Z, Wang C, Xiao Y, Sheng N, Chen Y, Xu Y, Zhang L, Mo W, Jing N, Hu G, NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development. J Cell Sci. 2009 Apr 15;122(Pt 8):1145-54 |
1 | J:257613 Kuony A, Michon F, Epithelial Markers aSMA, Krt14, and Krt19 Unveil Elements of Murine Lacrimal Gland Morphogenesis and Maturation. Front Physiol. 2017;8:739 |
1 | J:237343 Laresgoiti U, Nikolic MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL, Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016 Oct 15;143(20):3686-3699 |
1* | J:170545 Larsen HS, Aure MH, Peters SB, Larsen M, Messelt EB, Kanli Galtung H, Localization of AQP5 during development of the mouse submandibular salivary gland. J Mol Histol. 2011 Feb;42(1):71-81 |
2* | J:160026 Larsen HS, Ruus AK, Galtung HK, Aquaporin expression patterns in the developing mouse salivary gland. Eur J Oral Sci. 2009 Dec;117(6):655-62 |
1 | J:330439 Liu H, He L, Cheng Q, Luo W, Zhao T, Yang D, Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states. Int J Mol Med. 2022 Nov;50(5) |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:267889 Moon S, Im SK, Kim N, Youn H, Park UH, Kim JY, Kim AR, An SJ, Kim JH, Sun W, Hwang JT, Kim EJ, Um SJ, Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis. Cell Death Dis. 2018 Nov 2;9(11):1118 |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
1 | J:97215 Okubo T, Knoepfler PS, Eisenman RN, Hogan BL, Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation. Development. 2005 Mar;132(6):1363-74 |
1* | J:353621 Patel VN, Aure MH, Choi SH, Ball JR, Lane ED, Wang Z, Xu Y, Zheng C, Liu X, Martin D, Pailin JY, Prochazkova M, Kulkarni AB, van Kuppevelt TH, Ambudkar IS, Liu J, Hoffman MP, Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation. Nat Commun. 2024 Aug 31;15(1):7584 |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
Aqp7 aquaporin 7 (Synonyms: AQP7L, AQPap) | |
Results | Reference |
1* | J:151683 Parreira KS, Debaix H, Cnops Y, Geffers L, Devuyst O, Expression patterns of the aquaporin gene family during renal development: influence of genetic variability. Pflugers Arch. 2009 Aug;458(4):745-59 |
Aqp8 aquaporin 8 | |
Results | Reference |
1 | J:167016 Kobayashi K, Yasui M, Cellular and subcellular localization of aquaporins 1, 3, 8, and 9 in amniotic membranes during pregnancy in mice. Cell Tissue Res. 2010 Nov;342(2):307-16 |
1 | J:257613 Kuony A, Michon F, Epithelial Markers aSMA, Krt14, and Krt19 Unveil Elements of Murine Lacrimal Gland Morphogenesis and Maturation. Front Physiol. 2017;8:739 |
1* | J:160026 Larsen HS, Ruus AK, Galtung HK, Aquaporin expression patterns in the developing mouse salivary gland. Eur J Oral Sci. 2009 Dec;117(6):655-62 |
2* | J:295950 Luo H, Liu Y, Song Y, Hua Y, Zhu X, Aquaporin 1 affects pregnancy outcome and regulates aquaporin 8 and 9 expressions in the placenta. Cell Tissue Res. 2020 Sep;381(3):543-554 |
2* | J:321244 Luo H, Xie A, Hua Y, Wang J, Liu Y, Zhu X, Aquaporin 1 gene deletion affects the amniotic fluid volume and composition as well as the expression of other aquaporin water channels in placenta and fetal membranes. Clin Chim Acta. 2018 Jul;482:161-165 |
Aqp9 aquaporin 9 (Synonyms: 1700020I22Rik) | |
Results | Reference |
1 | J:167016 Kobayashi K, Yasui M, Cellular and subcellular localization of aquaporins 1, 3, 8, and 9 in amniotic membranes during pregnancy in mice. Cell Tissue Res. 2010 Nov;342(2):307-16 |
2* | J:295950 Luo H, Liu Y, Song Y, Hua Y, Zhu X, Aquaporin 1 affects pregnancy outcome and regulates aquaporin 8 and 9 expressions in the placenta. Cell Tissue Res. 2020 Sep;381(3):543-554 |
2* | J:321244 Luo H, Xie A, Hua Y, Wang J, Liu Y, Zhu X, Aquaporin 1 gene deletion affects the amniotic fluid volume and composition as well as the expression of other aquaporin water channels in placenta and fetal membranes. Clin Chim Acta. 2018 Jul;482:161-165 |
Aqp11 aquaporin 11 (Synonyms: 1700015P13Rik, sjds) | |
Results | Reference |
2* | J:161873 Larsen HS, Ruus AK, Schreurs O, Galtung HK, Aquaporin 11 in the developing mouse submandibular gland. Eur J Oral Sci. 2010 Feb;118(1):9-13 |
1* | J:151683 Parreira KS, Debaix H, Cnops Y, Geffers L, Devuyst O, Expression patterns of the aquaporin gene family during renal development: influence of genetic variability. Pflugers Arch. 2009 Aug;458(4):745-59 |
Ar androgen receptor | |
Results | Reference |
1* | J:324263 Aksel S, Cao M, Derpinghaus A, Baskin LS, Cunha GR, Ontogeny of mouse Sertoli, Leydig and peritubular myoid cells from embryonic day 10 to adulthood. Differentiation. 2022 Mar 7; |
1* | J:46947 Crocoll A, Zhu CC, Cato AC, Blum M, Expression of androgen receptor mRNA during mouse embryogenesis. Mech Dev. 1998 Mar;72(1-2):175-8 |
1* | J:74204 Drews U, Sulak O, Oppitz M, Immunohistochemical localisation of androgen receptor during sex-specific morphogenesis in the fetal mouse. Histochem Cell Biol. 2001 Nov;116(5):427-39 |
1 | J:182895 Kaftanovskaya EM, Feng S, Huang Z, Tan Y, Barbara AM, Kaur S, Truong A, Gorlov IP, Agoulnik AI, Suppression of insulin-like3 receptor reveals the role of beta-catenin and Notch signaling in gubernaculum development. Mol Endocrinol. 2011 Jan;25(1):170-83 |
1 | J:324237 Kajimoto M, Suzuki K, Ueda Y, Fujimoto K, Takeo T, Nakagata N, Hyuga T, Isono K, Yamada G, Androgen/Wnt/beta-catenin signal axis augments cell proliferation of the mouse erectile tissue, corpus cavernosum. Congenit Anom (Kyoto). 2022 May;62(3):123-133 |
1 | J:306453 Kajioka D, Suzuki K, Matsushita S, Hino S, Sato T, Takada S, Isono K, Takeo T, Kajimoto M, Nakagata N, Nakao M, Suyama M, DeFalco T, Miyagawa S, Yamada G, Sexual fate of murine external genitalia development: Conserved transcriptional competency for male-biased genes in both sexes. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2024067118 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1 | J:226927 Kumar D, Periasamy V, Freese M, Voigt A, Boehm U, In Utero Development of Kisspeptin/GnRH Neural Circuitry in Male Mice. Endocrinology. 2015 Sep;156(9):3084-90 |
1 | J:301558 Lee DH, Olson AW, Wang J, Kim WK, Mi J, Zeng H, Le V, Aldahl J, Hiroto A, Wu X, Sun Z, Androgen action in cell fate and communication during prostate development at single-cell resolution. Development. 2021 Jan 11;148(1):dev196048 |
1 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1 | J:173864 Murashima A, Miyagawa S, Ogino Y, Nishida-Fukuda H, Araki K, Matsumoto T, Kaneko T, Yoshinaga K, Yamamura K, Kurita T, Kato S, Moon AM, Yamada G, Essential roles of androgen signaling in Wolffian duct stabilization and epididymal cell differentiation. Endocrinology. 2011 Apr;152(4):1640-51 |
2* | J:316724 Pedernera E, Gomora MJ, Meneses I, De Ita M, Mendez C, Androgen receptor is expressed in mouse cardiomyocytes at prenatal and early postnatal developmental stages. BMC Physiol. 2017 Aug 14;17(1):7 |
1* | J:98380 Petiot A, Perriton CL, Dickson C, Cohn MJ, Development of the mammalian urethra is controlled by Fgfr2-IIIb. Development. 2005 May;132(10):2441-50 |
1 | J:159267 Plante J, Simard M, Rantakari P, Cote M, Provost PR, Poutanen M, Tremblay Y, Epithelial cells are the major site of hydroxysteroid (17beta) dehydrogenase 2 and androgen receptor expression in fetal mouse lungs during the period overlapping the surge of surfactant. J Steroid Biochem Mol Biol. 2009 Nov;117(4-5):139-45 |
1 | J:161760 Provost PR, Simard M, Tremblay Y, A link between lung androgen metabolism and the emergence of mature epithelial type II cells. Am J Respir Crit Care Med. 2004 Aug 1;170(3):296-305 |
1* | J:216758 Suzuki K, Numata T, Suzuki H, Raga DD, Ipulan LA, Yokoyama C, Matsushita S, Hamada M, Nakagata N, Nishinakamura R, Kume S, Takahashi S, Yamada G, Sexually dimorphic expression of Mafb regulates masculinization of the embryonic urethral formation. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16407-12 |
1* | J:122819 Tomaszewski J, Joseph A, Archambeault D, Yao HH, Essential roles of inhibin beta A in mouse epididymal coiling. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11322-7 |
1* | J:106945 Tremblay Y, Provost PR, 17beta-HSD type 5 expression and the emergence of differentiated epithelial Type II cells in fetal lung: A novel role for androgen during the surge of surfactant. Mol Cell Endocrinol. 2006 Mar 27;248(1-2):118-25 |
1* | J:176585 Zheng Z, Cohn MJ, Developmental basis of sexually dimorphic digit ratios. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16289-94 |
1 | J:33709 Zhou X, Kudo A, Kawakami H, Hirano H, Immunohistochemical localization of androgen receptor in mouse testicular germ cells during fetal and postnatal development. Anat Rec. 1996 Jul;245(3):509-18 |
Araf Araf proto-oncogene, serine/threonine kinase (Synonyms: 1200013E08Rik, A-Raf, Araf1) | |
Results | Reference |
1 | J:112971 Camarero G, Tyrsin OY, Xiang C, Pfeiffer V, Pleiser S, Wiese S, Gotz R, Rapp UR, Cortical migration defects in mice expressing A-RAF from the B-RAF locus. Mol Cell Biol. 2006 Oct;26(19):7103-15 |
Areg amphiregulin (Synonyms: AR, Mcub, Sdgf) | |
Results | Reference |
1 | J:361142 Ke X, van Soldt B, Vlahos L, Zhou Y, Qian J, George J, Capdevila C, Glass I, Yan K, Califano A, Cardoso WV, Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate. Dev Cell. 2024 Dec 9; |
1* | J:130339 Minami S, Iwamoto R, Mekada E, HB-EGF decelerates cell proliferation synergistically with TGFalpha in perinatal distal lung development. Dev Dyn. 2008 Jan;237(1):247-58 |
Arf6 ARF GTPase 6 | |
Results | Reference |
1 | J:237778 Hara Y, Fukaya M, Hayashi K, Kawauchi T, Nakajima K, Sakagami H, ADP Ribosylation Factor 6 Regulates Neuronal Migration in the Developing Cerebral Cortex through FIP3/Arfophilin-1-dependent Endosomal Trafficking of N-cadherin. eNeuro. 2016 Jul-Aug;3(4):ENEURO.0148-16.2016 |
Arfgef2 ARF guanine nucleotide exchange factor 2 (Synonyms: BIG2, E230011G24Rik) | |
Results | Reference |
2* | J:104597 Lu J, Tiao G, Folkerth R, Hecht J, Walsh C, Sheen V, Overlapping expression of ARFGEF2 and Filamin A in the neuroependymal lining of the lateral ventricles: insights into the cause of periventricular heterotopia. J Comp Neurol. 2006 Jan 20;494(3):476-84 |
1 | J:187673 Zhang J, Neal J, Lian G, Shi B, Ferland RJ, Sheen V, Brefeldin A-inhibited Guanine Exchange Factor 2 Regulates Filamin A Phosphorylation and Neuronal Migration. J Neurosci. 2012 Sep 5;32(36):12619-29 |
Arfrp1 ARF related protein 1 (Synonyms: 1500006I01Rik, MGC:6837) | |
Results | Reference |
1* | J:74645 Mueller AG, Moser M, Kluge R, Leder S, Blum M, Buttner R, Joost HG, Schurmann A, Embryonic Lethality Caused by Apoptosis during Gastrulation in Mice Lacking the Gene of the ADP-Ribosylation Factor-Related Protein 1. Mol Cell Biol. 2002 Mar;22(5):1488-94 |
Arg1 arginase, liver (Synonyms: AI, Arg-1, PGIF) | |
Results | Reference |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
Arg2 arginase type II (Synonyms: AII) | |
Results | Reference |
1 | J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90 |
Arglu1 arginine and glutamate rich 1 (Synonyms: 9430010O03Rik) | |
Results | Reference |
1 | J:339368 Yao F, Huang S, Liu J, Tan C, Xu M, Wang D, Huang M, Zhu Y, Huang X, He S, Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis. Cell Death Dis. 2023 Aug 23;14(8):543 |
Arhgap11a Rho GTPase activating protein 11A (Synonyms: 6530401L14Rik, GAP (1-12), mKIAA0013) | |
Results | Reference |
2* | J:334332 Pilaz LJ, Liu J, Joshi K, Tsunekawa Y, Musso CM, D'Arcy BR, Suzuki IK, Alsina FC, Kc P, Sethi S, Vanderhaeghen P, Polleux F, Silver DL, Subcellular mRNA localization and local translation of Arhgap11a in radial glial progenitors regulates cortical development. Neuron. 2023 Mar 15;111(6):839-856.e5 |
1 | J:308527 Xing L, Kubik-Zahorodna A, Namba T, Pinson A, Florio M, Prochazka J, Sarov M, Sedlacek R, Huttner WB, Expression of human-specific ARHGAP11B in mice leads to neocortex expansion and increased memory flexibility. EMBO J. 2021 Jul 1;40(13):e107093 |
Arhgap24 Rho GTPase activating protein 24 (Synonyms: 0610025G21Rik) | |
Results | Reference |
1 | J:317033 Xie C, Abrams SR, Herranz-Perez V, Garcia-Verdugo JM, Reiter JF, Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity. Dev Cell. 2021 Dec 20;56(24):3334-3348.e6 |
Arhgap35 Rho GTPase activating protein 35 (Synonyms: 6430596G11Rik, Grlf1, p190A, p190RhoGAP, P190 RhoGAP) | |
Results | Reference |
1 | J:101055 Kuo G, Arnaud L, Kronstad-O'Brien P, Cooper JA, Absence of Fyn and Src causes a reeler-like phenotype. J Neurosci. 2005 Sep 14;25(37):8578-86 |
Arhgdia Rho GDP dissociation inhibitor alpha (Synonyms: 5330430M07Rik, Rho-GDI, Rho GDIalpha) | |
Results | Reference |
1* | J:320610 Auguste D, Maier M, Baldwin C, Aoudjit L, Robins R, Gupta IR, Takano T, Disease-causing mutations of RhoGDIalpha induce Rac1 hyperactivation in podocytes. Small GTPases. 2016 Apr 2;7(2):107-21 |
1* | J:100306 Ferland RJ, Li X, Buhlmann JE, Bu X, Walsh CA, Lim B, Characterization of Rho-GDIgamma and Rho-GDIalpha mRNA in the developing and mature brain with an analysis of mice with targeted deletions of Rho-GDIgamma. Brain Res. 2005 Aug 23;1054(1):9-21 |
Arhgdig Rho GDP dissociation inhibitor gamma (Synonyms: Gdi5, Rho-GDI2, Rho-GDI-3, RIP2) | |
Results | Reference |
1* | J:100306 Ferland RJ, Li X, Buhlmann JE, Bu X, Walsh CA, Lim B, Characterization of Rho-GDIgamma and Rho-GDIalpha mRNA in the developing and mature brain with an analysis of mice with targeted deletions of Rho-GDIgamma. Brain Res. 2005 Aug 23;1054(1):9-21 |
Arhgef1 Rho guanine nucleotide exchange factor 1 (Synonyms: Lbcl2, Lsc) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:235617 Xiang X, Li S, Zhuang X, Shi L, Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways. FEBS Lett. 2016 Sep;590(17):2940-55 |
1* | J:241446 Xiang X, Zhuang X, Li S, Shi L, Arhgef1 is expressed in cortical neural progenitor cells and regulates neurite outgrowth of newly differentiated neurons. Neurosci Lett. 2017 Jan 18;638:27-34 |
Arhgef4 Rho guanine nucleotide exchange factor 4 (Synonyms: 9330140K16Rik, Asef, C230030N03Rik) | |
Results | Reference |
1* | J:237193 Chaboub LS, Manalo JM, Lee HK, Glasgow SM, Chen F, Kawasaki Y, Akiyama T, Kuo CT, Creighton CJ, Mohila CA, Deneen B, Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury. J Neurosci. 2016 Nov 23;36(47):11904-11917 |
Arhgef5 Rho guanine nucleotide exchange factor 5 (Synonyms: 2210412D05Rik) | |
Results | Reference |
1* | J:350269 Kim JY, Hwang HG, Jeon HJ, Kim SI, Kim MK, Kim JY, ARHGEF5 binds Drebrin and affects alpha-tubulin acetylation to direct neuronal morphogenesis and migration during mouse brain development. Front Mol Neurosci. 2024;17:1421932 |
Arhgef7 Rho guanine nucleotide exchange factor (Synonyms: betaPix, betaPix-b, betaPix-c, Cool, cool-1, p85SPR, Pak interacting exchange factor, PIX) | |
Results | Reference |
1* | J:84356 Yoshizawa M, Sone M, Matsuo N, Nagase T, Ohara O, Nabeshima Y, Hoshino M, Dynamic and coordinated expression profile of dbl-family guanine nucleotide exchange factors in the developing mouse brain. Gene Expr Patterns. 2003 Jun;3(3):375-81 |
Arhgef11 Rho guanine nucleotide exchange factor 11 (Synonyms: PDZ-RhoGEF, Prg) | |
Results | Reference |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
Arid1a AT-rich interaction domain 1A (Synonyms: 1110030E03Rik, BAF250a, Osa1, Smarcf1) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
1* | J:69532 Kozmik Z, Machon O, Kralova J, Kreslova J, Paces J, Vlcek C, Characterization of Mammalian Orthologues of the Drosophila osa Gene: cDNA Cloning, Expression, Chromosomal Localization, and Direct Physical Interaction with Brahma Chromatin-Remodeling Complex. Genomics. 2001 Apr 15;73(2):140-8 |
3 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
2 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
1* | J:316179 Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y, An epigenetic circuit controls neurogenic programs during neocortex development. Development. 2021;148:dev199772 |
Arid1b AT-rich interaction domain 1B (Synonyms: 9330189K18Rik, B230217J03Rik, mKIAA1235) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
3 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
Arid2 AT-rich interaction domain 2 (Synonyms: 1700124K17Rik, 4432409D24Rik, zipzap/p200) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
2 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
Arid3c AT-rich interaction domain 3C (Synonyms: OTTMUSG00000006683) | |
Results | Reference |
2 | J:357897 Renaux E, Baudouin C, Schakman O, Gay O, Martin M, Marchese D, Achouri Y, Rezsohazy R, Gofflot F, Clotman F, Arid3c identifies an uncharacterized subpopulation of V2 interneurons during embryonic spinal cord development. Front Cell Neurosci. 2024;18:1466056 |
Ark2c arkadia (RNF111) C-terminal like ring finger ubiquitin ligase 2C (Synonyms: 2900024M11Rik, Ark2c, G630064H08Rik, LOC225743, Rnf165) | |
Results | Reference |
1 | J:198828 Kelly CE, Thymiakou E, Dixon JE, Tanaka S, Godwin J, Episkopou V, Rnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extension. PLoS Biol. 2013;11(4):e1001538 |
Arl3 ADP-ribosylation factor-like 3 | |
Results | Reference |
2* | J:306328 Bhattarai SR, Begum S, Popow R, Ezratty EJ, The ciliary GTPase Arl3 maintains tissue architecture by directing planar spindle orientation during epidermal morphogenesis. Development. 2019 May 10;146(9):dev161885 |
Arl4a ADP-ribosylation factor-like 4A (Synonyms: Arl4) | |
Results | Reference |
1* | J:65970 Lin CY, Huang PH, Liao WL, Cheng HJ, Huang CF, Kuo JC, Patton WA, Massenburg D, Moss J, Lee FJ, ARL4, an ARF-like protein that is developmentally regulated and localized to nuclei and nucleoli. J Biol Chem. 2000 Dec 1;275(48):37815-23 |
Arl13b ADP-ribosylation factor-like 13B (Synonyms: A530097K21Rik, A930014M17Rik, Arl2l1, C530009C10Rik, hnn) | |
Results | Reference |
1 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1 | J:236794 Ezratty EJ, Pasolli HA, Fuchs E, A Presenilin-2-ARF4 trafficking axis modulates Notch signaling during epidermal differentiation. J Cell Biol. 2016 Jul 4;214(1):89-101 |
1 | J:315450 Giridhar PV, Bell SM, Sridharan A, Rajavelu P, Kitzmiller JA, Na CL, Kofron M, Brandt EB, Ericksen M, Naren AP, Moon C, Khurana Hershey GK, Whitsett JA, Airway Epithelial KIF3A Regulates Th2 Responses to Aeroallergens. J Immunol. 2016 Dec 1;197(11):4228-4239 |
1 | J:343556 Kretschmer V, Schneider S, Matthiessen PA, Reichert D, Hotaling N, Glassser G, Lieberwirth I, Bharti K, De Cegli R, Conte I, Nandrot EF, May-Simera HL, Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration. PLoS Biol. 2023 Dec;21(12):e3002402 |
1 | J:225435 Laclef C, Anselme I, Besse L, Catala M, Palmyre A, Baas D, Paschaki M, Pedraza M, Metin C, Durand B, Schneider-Maunoury S, The role of primary cilia in corpus callosum formation is mediated by production of the Gli3 repressor. Hum Mol Genet. 2015 Sep 1;24(17):4997-5014 |
1 | J:317151 Lavado A, Gangwar R, Pare J, Wan S, Fan Y, Cao X, YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development. Dev Biol. 2021 Dec;480:39-49 |
1* | J:346057 Lu D, Zhi Y, Su H, Lin X, Lin J, Shi Y, Yi W, Hong C, Zhang T, Fu Z, Chen LY, Zhao Z, Li R, Xu Z, Chen W, Wang N, Xu D, ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells. Cell Rep. 2024 Feb 24;43(3):113818 |
1 | J:309437 Nakagawa N, Li J, Yabuno-Nakagawa K, Eom TY, Cowles M, Mapp T, Taylor R, Anton ES, APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017 Aug 15;31(16):1679-1692 |
2 | J:317613 Patnaik SR, Kretschmer V, Brucker L, Schneider S, Volz AK, Oancea-Castillo LDR, May-Simera HL, Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation. Cell Mol Life Sci. 2019 Feb;76(4):757-775 |
1 | J:308707 Paulson D, Harms R, Ward C, Latterell M, Pazour GJ, Fink DM, Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation. Front Cell Dev Biol. 2021;9:672625 |
1 | J:346646 Sharma R, Kalot R, Levin Y, Babayeva S, Kachurina N, Chung CF, Liu KJ, Bouchard M, Torban E, The CPLANE protein Fuzzy regulates ciliogenesis by suppressing actin polymerization at the base of the primary cilium via p190A RhoGAP. Development. 2024 Mar 15;151(6):dev202322 |
Armcx2 armadillo repeat containing, X-linked 2 (Synonyms: 3230401N03Rik, Alex2) | |
Results | Reference |
2* | J:97474 Smith CA, McClive PJ, Sinclair AH, Temporal and spatial expression profile of the novel armadillo-related gene, Alex2, during testicular differentiation in the mouse embryo. Dev Dyn. 2005 May;233(1):188-93 |
Arnt aryl hydrocarbon receptor nuclear translocator (Synonyms: bHLHe2, D3Ertd557e, ESTM42, Hif1b) | |
Results | Reference |
2* | J:29264 Abbott BD, Probst MR, Developmental expression of two members of a new class of transcription factors: II. Expression of aryl hydrocarbon receptor nuclear translocator in the C57BL/6N mouse embryo. Dev Dyn. 1995 Oct;204(2):144-55 |
2* | J:180152 Bridges JP, Lin S, Ikegami M, Shannon JM, Conditional hypoxia inducible factor-1alpha induction in embryonic pulmonary epithelium impairs maturation and augments lymphangiogenesis. Dev Biol. 2012 Feb 1;362(1):24-41 |
1* | J:134028 Levesque BM, Zhou S, Shan L, Johnston P, Kong Y, Degan S, Sunday ME, NPAS1 regulates branching morphogenesis in embryonic lung. Am J Respir Cell Mol Biol. 2007 Apr;36(4):427-34 |
1 | J:142539 Vezina CM, Allgeier SH, Moore RW, Lin TM, Bemis JC, Hardin HA, Gasiewicz TA, Peterson RE, Dioxin causes ventral prostate agenesis by disrupting dorsoventral patterning in developing mouse prostate. Toxicol Sci. 2008 Dec;106(2):488-96 |
1 | J:150793 Zhou S, Degan S, Potts EN, Foster WM, Sunday ME, NPAS3 is a trachealess homolog critical for lung development and homeostasis. Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11691-6 |
Arnt2 aryl hydrocarbon receptor nuclear translocator 2 (Synonyms: bHLHe1, mKIAA0307) | |
Results | Reference |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
Arpc2 actin related protein 2/3 complex, subunit 2 (Synonyms: 2210023N03Rik, p34-Arc) | |
Results | Reference |
1* | J:95254 Grove M, Demyanenko G, Echarri A, Zipfel PA, Quiroz ME, Rodriguiz RM, Playford M, Martensen SA, Robinson MR, Wetsel WC, Maness PF, Pendergast AM, ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory. Mol Cell Biol. 2004 Dec;24(24):10905-22 |
1 | J:235720 Wang PS, Chou FS, Ramachandran S, Xia S, Chen HY, Guo F, Suraneni P, Maher BJ, Li R, Crucial roles of the Arp2/3 complex during mammalian corticogenesis. Development. 2016 Aug 1;143(15):2741-52 |
Arrb1 arrestin, beta 1 (Synonyms: 1200006I17Rik, beta-arrestin1) | |
Results | Reference |
1 | J:159121 Zhang M, Liu X, Zhang Y, Zhao J, Loss of betaarrestin1 and betaarrestin2 contributes to pulmonary hypoplasia and neonatal lethality in mice. Dev Biol. 2010 Mar 15;339(2):407-17 |
Arrb2 arrestin, beta 2 (Synonyms: Arr3, arrestin 3, beta arr2, beta-arrestin-2, beta-arrestin2) | |
Results | Reference |
1 | J:159121 Zhang M, Liu X, Zhang Y, Zhao J, Loss of betaarrestin1 and betaarrestin2 contributes to pulmonary hypoplasia and neonatal lethality in mice. Dev Biol. 2010 Mar 15;339(2):407-17 |
Arsb arylsulfatase B (Synonyms: 1110007C02Rik, As-1, As1, As1-r, As-1r, As1-s, As-1s, As1-t, As-1t, Asr-1, Ast-1) | |
Results | Reference |
1* | J:160587 Ratzka A, Mundlos S, Vortkamp A, Expression patterns of sulfatase genes in the developing mouse embryo. Dev Dyn. 2010 Jun;239(6):1779-88 |
Arsi arylsulfatase i | |
Results | Reference |
1* | J:160587 Ratzka A, Mundlos S, Vortkamp A, Expression patterns of sulfatase genes in the developing mouse embryo. Dev Dyn. 2010 Jun;239(6):1779-88 |
Arsj arylsulfatase J (Synonyms: 9330196J05Rik) | |
Results | Reference |
1* | J:160587 Ratzka A, Mundlos S, Vortkamp A, Expression patterns of sulfatase genes in the developing mouse embryo. Dev Dyn. 2010 Jun;239(6):1779-88 |
Arx aristaless related homeobox (Synonyms: Arx1) | |
Results | Reference |
1 | J:156329 Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L, Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. J Biol Chem. 2009 Nov 6;284(45):31236-48 |
1 | J:76798 Bienvenu T, Poirier K, Friocourt G, Bahi N, Beaumont D, Fauchereau F, Ben Jeema L, Zemni R, Vinet MC, Francis F, Couvert P, Gomot M, Moraine C, van Bokhoven H, Kalscheuer V, Frints S, Gecz J, Ohzaki K, Chaabouni H, Fryns JP, Desportes V, Beldjord C, Chelly J, ARX, a novel Prd-class-homeobox gene highly expressed in the telencephalon, is mutated in X-linked mental retardation. Hum Mol Genet. 2002 Apr 15;11(8):981-91 |
2* | J:141473 Biressi S, Messina G, Collombat P, Tagliafico E, Monteverde S, Benedetti L, Cusella De Angelis MG, Mansouri A, Ferrari S, Tajbakhsh S, Broccoli V, Cossu G, The homeobox gene Arx is a novel positive regulator of embryonic myogenesis. Cell Death Differ. 2008 Jan;15(1):94-104 |
1 | J:282102 Canizares MA, Albors AR, Singer G, Suttie N, Gorkic M, Felts P, Storey KG, Multiple steps characterise ventricular layer attrition to form the ependymal cell lining of the adult mouse spinal cord central canal. J Anat. 2019 Oct 31; |
1 | J:129103 Chao CS, Loomis ZL, Lee JE, Sussel L, Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells. Dev Biol. 2007 Dec 15;312(2):523-32 |
1* | J:98171 Cobos I, Broccoli V, Rubenstein JL, The vertebrate ortholog of Aristaless is regulated by Dlx genes in the developing forebrain. J Comp Neurol. 2005 Mar 14;483(3):292-303 |
1 | J:229227 Colasante G, Simonet JC, Calogero R, Crispi S, Sessa A, Cho G, Golden JA, Broccoli V, ARX regulates cortical intermediate progenitor cell expansion and upper layer neuron formation through repression of Cdkn1c. Cereb Cortex. 2015 Feb;25(2):322-35 |
2 | J:86206 Collombat P, Mansouri A, Hecksher-Sorensen J, Serup P, Krull J, Gradwohl G, Gruss P, Opposing actions of Arx and Pax4 in endocrine pancreas development. Genes Dev. 2003 Oct 15;17(20):2591-603 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:107405 Hirata T, Nakazawa M, Yoshihara S, Miyachi H, Kitamura K, Yoshihara Y, Hibi M, Zinc-finger gene Fez in the olfactory sensory neurons regulates development of the olfactory bulb non-cell-autonomously. Development. 2006 Apr;133(8):1433-43 |
2 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:108229 Kappeler C, Saillour Y, Baudoin JP, Tuy FP, Alvarez C, Houbron C, Gaspar P, Hamard G, Chelly J, Metin C, Francis F, Branching and nucleokinesis defects in migrating interneurons derived from doublecortin knockout mice. Hum Mol Genet. 2006 May 1;15(9):1387-400 |
2 | J:176201 Kordowich S, Collombat P, Mansouri A, Serup P, Arx and Nkx2.2 compound deficiency redirects pancreatic alpha- and beta-cell differentiation to a somatostatin/ghrelin co-expressing cell lineage. BMC Dev Biol. 2011;11:52 |
1 | J:244498 Lee B, Lee M, Song S, Loi LD, Lam DT, Yoon J, Baek K, Curtis DJ, Jeong Y, Specification of neurotransmitter identity by Tal1 in thalamic nuclei. Dev Dyn. 2017 Oct;246(10):749-758 |
2 | J:335087 Lim Y, Cho IT, Golden JA, Cho G, Generation of FLAG-tagged Arx knock-in mouse model. Genesis. 2022 Jul;60(6-7):e23479 |
1 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1* | J:88461 Poirier K, Van Esch H, Friocourt G, Saillour Y, Bahi N, Backer S, Souil E, Castelnau-Ptakhine L, Beldjord C, Francis F, Bienvenu T, Chelly J, Neuroanatomical distribution of ARX in brain and its localisation in GABAergic neurons. Brain Res Mol Brain Res. 2004 Mar 17;122(1):35-46 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:287411 Tran HN, Park W, Seong S, Jeong JE, Nguyen QH, Yoon J, Baek K, Jeong Y, Tcf7l2 transcription factor is required for the maintenance, but not the initial specification, of the neurotransmitter identity in the caudal thalamus. Dev Dyn. 2020 May;249(5):646-655 |
Asah1 N-acylsphingosine amidohydrolase 1 (Synonyms: 2310081N20Rik, acid ceramidase) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Asah2 N-acylsphingosine amidohydrolase 2 (Synonyms: neutral/alkaline ceramidase) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Asap2 ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 (Synonyms: 6530401G17Rik, Ddef2, LOC385250) | |
Results | Reference |
1* | J:224930 Cheerathodi M, Vincent JJ, Ballif BA, Quantitative comparison of CrkL-SH3 binding proteins from embryonic murine brain and liver: Implications for developmental signaling and the quantification of protein species variants in bottom-up proteomics. J Proteomics. 2015 Jul 1;125:104-11 |
Asb2 ankyrin repeat and SOCS box-containing 2 (Synonyms: 1110008E15Rik) | |
Results | Reference |
1 | J:306706 Metais A, Lamsoul I, Melet A, Uttenweiler-Joseph S, Poincloux R, Stefanovic S, Valiere A, Gonzalez de Peredo A, Stella A, Burlet-Schiltz O, Zaffran S, Lutz PG, Moog-Lutz C, Asb2alpha-Filamin A Axis Is Essential for Actin Cytoskeleton Remodeling During Heart Development. Circ Res. 2018 Mar 16;122(6):e34-e48 |
Asb4 ankyrin repeat and SOCS box-containing 4 (Synonyms: 8430401O13Rik) | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Ascl1 achaete-scute family bHLH transcription factor 1 (Synonyms: ASH1, bHLHa46, Mash1) | |
Results | Reference |
1 | J:60107 Allen T, Lobe CG, A comparison of Notch, Hes and Grg expression during murine embryonic and post-natal development. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):687-708 |
1 | J:287136 Aslanpour S, Han S, Schuurmans C, Kurrasch DM, Neurog2 Acts as a Classical Proneural Gene in the Ventromedial Hypothalamus and Is Required for the Early Phase of Neurogenesis. J Neurosci. 2020 Apr 29;40(18):3549-3563 |
1* | J:229480 Baker JL, Wood B, Karpinski BA, LaMantia AS, Maynard TM, Testicular receptor 2, Nr2c1, is associated with stem cells in the developing olfactory epithelium and other cranial sensory and skeletal structures. Gene Expr Patterns. 2016 Jan;20(1):71-9 |
1 | J:117032 Battiste J, Helms AW, Kim EJ, Savage TK, Lagace DC, Mandyam CD, Eisch AJ, Miyoshi G, Johnson JE, Ascl1 defines sequentially generated lineage-restricted neuronal and oligodendrocyte precursor cells in the spinal cord. Development. 2007 Jan;134(2):285-93 |
1 | J:50518 Brown NL, Kanekar S, Vetter ML, Tucker PK, Gemza DL, Glaser T, Math5 encodes a murine basic helix-loop-helix transcription factor expressed during early stages of retinal neurogenesis. Development. 1998 Dec;125(23):4821-33 |
1* | J:171072 Carre A, Rachdi L, Tron E, Richard B, Castanet M, Schlumberger M, Bidart JM, Szinnai G, Polak M, Hes1 is required for appropriate morphogenesis and differentiation during mouse thyroid gland development. PLoS One. 2011;6(2):e16752 |
1 | J:286635 Chen SY, Lu KM, Ko HA, Huang TH, Hao JH, Yan YT, Chang SL, Evans SM, Liu FC, Parcellation of the striatal complex into dorsal and ventral districts. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7418-7429 |
1 | J:133461 Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH, Schier AF, Dulac C, Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 2008 Jan 10;57(1):41-55 |
1* | J:61328 Cohen DR, Cheng CW, Cheng SH, Hui C, Expression of two novel mouse iroquois homeobox genes during neurogenesis. Mech Dev. 2000 Mar 1;91(1-2):317-21 |
1 | J:136319 Duggan CD, Demaria S, Baudhuin A, Stafford D, Ngai J, Foxg1 is required for development of the vertebrate olfactory system. J Neurosci. 2008 May 14;28(20):5229-39 |
1 | J:336102 Eenjes E, Benthem F, Boerema-de Munck A, Buscop-van Kempen M, Tibboel D, Rottier RJ, Distinct roles for SOX2 and SOX21 in differentiation, distribution and maturation of pulmonary neuroendocrine cells. Cell Mol Life Sci. 2023 Mar 3;80(3):79 |
1 | J:176045 Gokoffski KK, Wu HH, Beites CL, Kim J, Kim EJ, Matzuk MM, Johnson JE, Lander AD, Calof AL, Activin and GDF11 collaborate in feedback control of neuroepithelial stem cell proliferation and fate. Development. 2011 Oct;138(19):4131-42 |
1 | J:176609 Goldberg LB, Aujla PK, Raetzman LT, Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis. Dev Biol. 2011 Oct 1;358(1):23-32 |
1 | J:149261 Grimaldi P, Parras C, Guillemot F, Rossi F, Wassef M, Origins and control of the differentiation of inhibitory interneurons and glia in the cerebellum. Dev Biol. 2009 Apr 15;328(2):422-33 |
1 | J:188519 Guha A, Vasconcelos M, Cai Y, Yoneda M, Hinds A, Qian J, Li G, Dickel L, Johnson JE, Kimura S, Guo J, McMahon J, McMahon AP, Cardoso WV, Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12592-7 |
1* | J:14701 Guillemot F, Joyner AL, Dynamic expression of the murine Achaete-Scute homologue Mash-1 in the developing nervous system. Mech Dev. 1993 Aug;42(3):171-85 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:310880 Han S, Okawa S, Wilkinson GA, Ghazale H, Adnani L, Dixit R, Tavares L, Faisal I, Brooks MJ, Cortay V, Zinyk D, Sivitilli A, Li S, Malik F, Ilnytskyy Y, Angarica VE, Gao J, Chinchalongporn V, Oproescu AM, Vasan L, Touahri Y, David LA, Raharjo E, Kim JW, Wu W, Rahmani W, Chan JA, Kovalchuk I, Attisano L, Kurrasch D, Dehay C, Swaroop A, Castro DS, Biernaskie J, Del Sol A, Schuurmans C, Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding. Neuron. 2021 Sep 15;109(18):2847-2863.e11 |
1 | J:354192 He H, Bell SM, Davis AK, Zhao S, Sridharan A, Na CL, Guo M, Xu Y, Snowball J, Swarr DT, Zacharias WJ, Whitsett JA, PRDM3/16 regulate chromatin accessibility required for NKX2-1 mediated alveolar epithelial differentiation and function. Nat Commun. 2024 Sep 16;15(1):8112 |
1 | J:79390 Huber K, Bruhl B, Guillemot F, Olson EN, Ernsberger U, Unsicker K, Development of chromaffin cells depends on MASH1 function. Development. 2002 Oct;129(20):4729-38 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
1 | J:64088 Ito T, Udaka N, Yazawa T, Okudela K, Hayashi H, Sudo T, Guillemot F, Kageyama R, Kitamura H, Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development. 2000 Sep;127(18):3913-21 |
1 | J:147995 Kawauchi S, Kim J, Santos R, Wu HH, Lander AD, Calof AL, Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11. Development. 2009 May;136(9):1453-64 |
1* | J:252114 Kohli V, Nardini D, Ehrman LA, Waclaw RR, Characterization of Glcci1 expression in a subpopulation of lateral ganglionic eminence progenitors in the mouse telencephalon. Dev Dyn. 2018 Jan;247(1):222-228 |
1 | J:138261 Kokubu H, Ohtsuka T, Kageyama R, Mash1 is required for neuroendocrine cell development in the glandular stomach. Genes Cells. 2008 Jan;13(1):41-51 |
1 | J:240536 Martin-Ibanez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Garcia-Diaz Barriga G, Edel MJ, Vicario-Abejon C, Alberch J, Girault JA, Chan S, Kastner P, Canals JM, Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017 Apr 15;144(8):1566-1577 |
1* | J:137801 Nakayama A, Miura H, Shindo Y, Kusakabe Y, Tomonari H, Harada S, Expression of the basal cell markers of taste buds in the anterior tongue and soft palate of the mouse embryo. J Comp Neurol. 2008 Jul 10;509(2):211-24 |
1 | J:285050 Ochi S, Imaizumi Y, Shimojo H, Miyachi H, Kageyama R, Oscillatory expression of Hes1 regulates cell proliferation and neuronal differentiation in the embryonic brain. Development. 2020 Feb 26;147(4):dev182204 |
1 | J:206963 Orieux G, Picault L, Slembrouck A, Roger JE, Guillonneau X, Sahel JA, Saule S, McPherson JP, Goureau O, Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells. J Neurosci. 2014 Jan 22;34(4):1530-41 |
1 | J:173538 Packard A, Schnittke N, Romano RA, Sinha S, Schwob JE, {Delta}Np63 regulates stem cell dynamics in the Mammalian olfactory epithelium. J Neurosci. 2011 Jun 15;31(24):8748-59 |
2 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:168035 Shikata Y, Okada T, Hashimoto M, Ellis T, Matsumaru D, Shiroishi T, Ogawa M, Wainwright B, Motoyama J, Ptch1-mediated dosage-dependent action of Shh signaling regulates neural progenitor development at late gestational stages. Dev Biol. 2011 Jan 15;349(2):147-59 |
1 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1* | J:64588 Toresson H, Potter SS, Campbell K, Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for pax6 and gsh2. Development. 2000 Oct;127(20):4361-71 |
1 | J:163859 Tucker ES, Lehtinen MK, Maynard T, Zirlinger M, Dulac C, Rawson N, Pevny L, Lamantia AS, Proliferative and transcriptional identity of distinct classes of neural precursors in the mammalian olfactory epithelium. Development. 2010 Aug 1;137(15):2471-81 |
2 | J:96850 van Tuyl M, Groenman F, Kuliszewski M, Ridsdale R, Wang J, Tibboel D, Post M, Overexpression of lunatic fringe does not affect epithelial cell differentiation in the developing mouse lung. Am J Physiol Lung Cell Mol Physiol. 2005 Apr;288(4):L672-82 |
1 | J:309451 Vinsland E, Baskaran P, Mihaylov SR, Hobbs C, Wood H, Bouybayoune I, Shah K, Houart C, Tee AR, Murn J, Fernandes C, Bateman JM, The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021 Aug 11;11(1):16299 |
1 | J:233479 Vong KI, Leung CK, Behringer RR, Kwan KM, Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum. Mol Brain. 2015;8:25 |
1 | J:147161 Wang B, Waclaw RR, Allen ZJ 2nd, Guillemot F, Campbell K, Ascl1 is a required downstream effector of Gsx gene function in the embryonic mouse telencephalon. Neural Dev. 2009;4:5 |
1 | J:238248 Wang L, Hou S, Han YG, Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex. Nat Neurosci. 2016 Jul;19(7):888-96 |
1 | J:305176 Wei Y, Han X, Zhao C, PDK1 regulates the survival of the developing cortical interneurons. Mol Brain. 2020 May 4;13(1):65 |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
2 | J:264125 Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z, SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. Development. 2018 Jul 23;145(14):dev165456 |
1 | J:270427 Yabut OR, Fernandez G, Huynh T, Yoon K, Pleasure SJ, Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis. Cell Rep. 2015 Sep 29;12(12):2021-34 |
1* | J:214315 Yamada M, Clark J, Iulianella A, MLLT11/AF1q is differentially expressed in maturing neurons during development. Gene Expr Patterns. 2014 Jul;15(2):80-7 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
1 | J:112960 Zhu X, Zhang J, Tollkuhn J, Ohsawa R, Bresnick EH, Guillemot F, Kageyama R, Rosenfeld MG, Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. Genes Dev. 2006 Oct 1;20(19):2739-53 |
Ascl2 achaete-scute family bHLH transcription factor 2 (Synonyms: 2410083I15Rik, bHLHa45, Mash2) | |
Results | Reference |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
1 | J:135158 Moriyama M, Durham AD, Moriyama H, Hasegawa K, Nishikawa S, Radtke F, Osawa M, Multiple roles of Notch signaling in the regulation of epidermal development. Dev Cell. 2008 Apr;14(4):594-604 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
Ascl3 achaete-scute family bHLH transcription factor 3 (Synonyms: bHLHa42, ICRFP703B1614Q5.4, ICRFP703N2430Q5.4, Sgn1) | |
Results | Reference |
1 | J:135661 Sugimori M, Nagao M, Parras CM, Nakatani H, Lebel M, Guillemot F, Nakafuku M, Ascl1 is required for oligodendrocyte development in the spinal cord. Development. 2008 Apr;135(7):1271-81 |
1 | J:259982 Weng PL, Vinjamuri M, Ovitt CE, Ascl3 transcription factor marks a distinct progenitor lineage for non-neuronal support cells in the olfactory epithelium. Sci Rep. 2016 Dec 2;6:38199 |
Ash1l ASH1 like histone lysine methyltransferase (Synonyms: 8030453L17Rik, chromatin remodeling factor, E430018P19Rik, KMT2H) | |
Results | Reference |
1* | J:267598 Castiglioni I, Caccia R, Garcia-Manteiga JM, Ferri G, Caretti G, Molineris I, Nishioka K, Gabellini D, The Trithorax protein Ash1L promotes myoblast fusion by activating Cdon expression. Nat Commun. 2018 Nov 28;9(1):5026 |
1 | J:314124 Gao Y, Duque-Wilckens N, Aljazi MB, Wu Y, Moeser AJ, Mias GI, Robison AJ, He J, Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors. Commun Biol. 2021 Jun 18;4(1):756 |
Ash2l ASH2 like histone lysine methyltransferase complex subunit | |
Results | Reference |
2* | J:294282 Li L, Ruan X, Wen C, Chen P, Liu W, Zhu L, Xiang P, Zhang X, Wei Q, Hou L, Yin B, Yuan J, Qiang B, Shu P, Peng X, The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019 Jul 16;28(3):698-711.e5 |
1 | J:348702 Wang Q, Zeng S, Liang Y, Zhou R, Wang D, ASH2L Mediates Epidermal Differentiation and Hair Follicle Morphogenesis through H3K4me3 Modification. J Invest Dermatol. 2024 Apr 4; |
Asic1 acid-sensing ion channel 1 (Synonyms: Accn2, ASIC, ASIC1a, ASIC1b, ASIC1 beta, ASICalpha, B530003N02Rik, BNaC2) | |
Results | Reference |
1 | J:231738 Reed-Geaghan EG, Wright MC, See LA, Adelman PC, Lee KH, Koerber HR, Maricich SM, Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. J Neurosci. 2016 Apr 13;36(15):4362-76 |
Asns asparagine synthetase | |
Results | Reference |
1 | J:253948 Magarin M, Pohl T, Lill A, Schulz H, Blaschke F, Heuser A, Thierfelder L, Donath S, Drenckhahn JD, Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress. J Mol Cell Cardiol. 2016 Aug;97:1-14 |
Asph aspartate-beta-hydroxylase (Synonyms: 2310005F16Rik, 3110001L23Rik, aspartyl beta-hydroxylase, BAH, calsequestrin-binding protein, cI-37, jumbug, junctate, Junctin) | |
Results | Reference |
1* | J:97586 Hong S, Kim TW, Choi I, Woo JM, Oh J, Park WJ, Kim do H, Cho C, Complementary DNA cloning, genomic characterization and expression analysis of a mammalian gene encoding histidine-rich calcium binding protein. Biochim Biophys Acta. 2005 Mar 10;1727(3):188-96 |
Aspm abnormal spindle microtubule assembly (Synonyms: Aspm, Calmbp1, D330028K02Rik, MCPH5, Sha1) | |
Results | Reference |
1* | J:79564 Bond J, Roberts E, Mochida GH, Hampshire DJ, Scott S, Askham JM, Springell K, Mahadevan M, Crow YJ, Markham AF, Walsh CA, Woods CG, ASPM is a major determinant of cerebral cortical size. Nat Genet. 2002 Oct;32(2):316-20 |
1* | J:205524 Fujimori A, Itoh K, Goto S, Hirakawa H, Wang B, Kokubo T, Kito S, Tsukamoto S, Fushiki S, Disruption of Aspm causes microcephaly with abnormal neuronal differentiation. Brain Dev. 2014 Sep;36(8):661-9 |
1 | J:290729 Grundl M, Walz S, Hauf L, Schwab M, Werner KM, Spahr S, Schulte C, Maric HM, Ade CP, Gaubatz S, Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes. PLoS Genet. 2020 May;16(5):e1008818 |
1* | J:270210 Loo L, Simon JM, Xing L, McCoy ES, Niehaus JK, Guo J, Anton ES, Zylka MJ, Single-cell transcriptomic analysis of mouse neocortical development. Nat Commun. 2019 Jan 11;10(1):134 |
1* | J:79525 Luers GH, Michels M, Schwaab U, Franz T, Murine calmodulin binding protein 1 (Calmbp1): tissue-specific expression during development and in adult tissues. Mech Dev. 2002 Oct;118(1-2):229-32 |
Asprv1 aspartic peptidase, retroviral-like 1 (Synonyms: 2300003P22Rik, SASP, SASPase, Taps, TPA-induced aspartic proteinase-like) | |
Results | Reference |
1 | J:116504 Matsui T, Kinoshita-Ida Y, Hayashi-Kisumi F, Hata M, Matsubara K, Chiba M, Katahira-Tayama S, Morita K, Miyachi Y, Tsukita S, Mouse homologue of skin-specific retroviral-like aspartic protease involved in wrinkle formation. J Biol Chem. 2006 Sep 15;281(37):27512-25 |
1 | J:107328 Rhiemeier V, Breitenbach U, Richter KH, Gebhardt C, Vogt I, Hartenstein B, Furstenberger G, Mauch C, Hess J, Angel P, A novel aspartic proteinase-like gene expressed in stratified epithelia and squamous cell carcinoma of the skin. Am J Pathol. 2006 Apr;168(4):1354-64 |
Ass1 argininosuccinate synthetase 1 (Synonyms: ASS, Ass-1, fold) | |
Results | Reference |
1 | J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90 |
Astn2 astrotactin 2 (Synonyms: 1d8, Astnl) | |
Results | Reference |
1* | J:228899 Chang H, Cahill H, Smallwood PM, Wang Y, Nathans J, Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles. PLoS Genet. 2015 Sep;11(9):e1005532 |
1* | J:161514 Wilson PM, Fryer RH, Fang Y, Hatten ME, Astn2, a novel member of the astrotactin gene family, regulates the trafficking of ASTN1 during glial-guided neuronal migration. J Neurosci. 2010 Jun 23;30(25):8529-40 |
Asxl1 ASXL transcriptional regulator 1 (Synonyms: mKIAA0978) | |
Results | Reference |
2 | J:267889 Moon S, Im SK, Kim N, Youn H, Park UH, Kim JY, Kim AR, An SJ, Kim JH, Sun W, Hwang JT, Kim EJ, Um SJ, Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis. Cell Death Dis. 2018 Nov 2;9(11):1118 |
Asxl3 ASXL transcriptional regulator 3 (Synonyms: C230079D11Rik, D430002O22Rik, D930044O18Rik, LOC381127) | |
Results | Reference |
1 | J:338889 Siguero-Alvarez M, Salguero-Jimenez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sanchez-Saez F, Pineiro-Sabaris R, Felipe-Medina N, Torroja C, Gomez MJ, Sabater-Molina M, Escriba R, Richaud-Patin I, Iglesias-Garcia O, Sbroggio M, Callejas S, O'Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibanez B, Monserrat L, Perez-Pomares JM, Sanchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL, A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation. 2023 Jan 3;147(1):47-65 |
Atad3a ATPase family, AAA domain containing 3A (Synonyms: 2400004H09Rik, Tob3) | |
Results | Reference |
1* | J:331874 Lee H, Kim DW, Deletion of ATAD3A inhibits osteogenesis by impairing mitochondria structure and function in pre-osteoblast. Dev Dyn. 2022 Dec;251(12):1982-2000 |
Ate1 arginyltransferase 1 (Synonyms: Ate1_1, Ate1_2, Ate1_3, Ate1_4) | |
Results | Reference |
1 | J:159224 Kurosaka S, Leu NA, Zhang F, Bunte R, Saha S, Wang J, Guo C, He W, Kashina A, Arginylation-dependent neural crest cell migration is essential for mouse development. PLoS Genet. 2010;6(3):e1000878 |
1* | J:77750 Kwon YT, Kashina AS, Davydov IV, Hu RG, An JY, Seo JW, Du F, Varshavsky A, An essential role of N-terminal arginylation in cardiovascular development. Science. 2002 Jul 5;297(5578):96-9 |
Atf1 activating transcription factor 1 | |
Results | Reference |
1 | J:263373 Williams MA, Biguetti C, Romero-Bustillos M, Maheshwari K, Dinckan N, Cavalla F, Liu X, Silva R, Akyalcin S, Uyguner ZO, Vieira AR, Amendt BA, Fakhouri WD, Letra A, Colorectal Cancer-Associated Genes Are Associated with Tooth Agenesis and May Have a Role in Tooth Development. Sci Rep. 2018 Feb 14;8(1):2979 |
Atf4 activating transcription factor 4 (Synonyms: Atf-4, C/ATF, CREB2, TAXREB67) | |
Results | Reference |
1 | J:158314 Firtina Z, Danysh BP, Bai X, Gould DB, Kobayashi T, Duncan MK, Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract. J Biol Chem. 2009 Dec 18;284(51):35872-84 |
1* | J:168632 Firtina Z, Duncan MK, Unfolded Protein Response (UPR) is activated during normal lens development. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):135-43 |
1* | J:167101 Frank CL, Ge X, Xie Z, Zhou Y, Tsai LH, Control of activating transcription factor 4 (ATF4) persistence by multisite phosphorylation impacts cell cycle progression and neurogenesis. J Biol Chem. 2010 Oct 22;285(43):33324-37 |
1 | J:270164 Guo M, Du Y, Gokey JJ, Ray S, Bell SM, Adam M, Sudha P, Perl AK, Deshmukh H, Potter SS, Whitsett JA, Xu Y, Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth. Nat Commun. 2019 Jan 3;10(1):37 |
2 | J:152843 Luo J, Zhou W, Zhou X, Li D, Weng J, Yi Z, Cho SG, Li C, Yi T, Wu X, Li XY, de Crombrugghe B, Hook M, Liu M, Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development. 2009 Aug;136(16):2747-56 |
1 | J:158241 Saito A, Hino S, Murakami T, Kanemoto S, Kondo S, Saitoh M, Nishimura R, Yoneda T, Furuichi T, Ikegawa S, Ikawa M, Okabe M, Imaizumi K, Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis. Nat Cell Biol. 2009 Oct;11(10):1197-204 |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
1* | J:332497 Tang X, Wei W, Snowball JM, Nakayasu ES, Bell SM, Ansong C, Lin X, Whitsett JA, EMC3 regulates mesenchymal cell survival via control of the mitotic spindle assembly. iScience. 2023 Jan 20;26(1):105667 |
2* | J:154906 Wang W, Lian N, Li L, Moss HE, Wang W, Perrien DS, Elefteriou F, Yang X, Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription. Development. 2009 Dec;136(24):4143-53 |
1 | J:172737 Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RA, Peterson AS, Solloway MJ, Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol. 2011 May 30;193(5):935-51 |
1* | J:148804 Yu VW, Akhouayri O, St-Arnaud R, FIAT is co-expressed with its dimerization target ATF4 in early osteoblasts, but not in osteocytes. Gene Expr Patterns. 2009 Jun;9(5):335-40 |
Atf5 activating transcription factor 5 (Synonyms: AFTA, Atf7, Atfx, ODA-10) | |
Results | Reference |
1* | J:78914 Hansen MB, Mitchelmore C, Kjaerulff KM, Rasmussen TE, Pedersen KM, Jensen NA, Mouse Atf5: molecular cloning of two novel mRNAs, genomic organization, and odorant sensory neuron localization. Genomics. 2002 Sep;80(3):344-50 |
1* | J:224807 Lee HY, Angelastro JM, Kenney AM, Mason CA, Greene LA, Reciprocal actions of ATF5 and Shh in proliferation of cerebellar granule neuron progenitor cells. Dev Neurobiol. 2012 Jun;72(6):789-804 |
1* | J:153077 Satake H, Ito K, Takahara M, Furukawa T, Takagi M, Ogino T, Shinomura T, Spatio-temporal expression of activating transcription factor 5 in the skeletal development of mouse limb. Dev Growth Differ. 2009 Sep;51(7):669-76 |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
1 | J:172737 Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RA, Peterson AS, Solloway MJ, Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol. 2011 May 30;193(5):935-51 |
Atf6 activating transcription factor 6 (Synonyms: 9130025P16Rik, Atf6alpha, ESTM49) | |
Results | Reference |
2* | J:294896 Aryal YP, Lee ES, Kim TY, Sung S, Kim JY, An SY, Jung JK, Ha JH, Suh JY, Yamamoto H, Sohn WJ, Cho SW, Lee Y, An CH, Kim JY, Stage-specific expression patterns of ER stress-related molecules in mice molars: Implications for tooth development. Gene Expr Patterns. 2020 Sep;37:119130 |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
1 | J:158314 Firtina Z, Danysh BP, Bai X, Gould DB, Kobayashi T, Duncan MK, Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract. J Biol Chem. 2009 Dec 18;284(51):35872-84 |
1* | J:168632 Firtina Z, Duncan MK, Unfolded Protein Response (UPR) is activated during normal lens development. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):135-43 |
1* | J:247203 Guo F, Han X, Wu Z, Cheng Z, Hu Q, Zhao Y, Wang Y, Liu C, ATF6a, a Runx2-activable transcription factor, is a new regulator of chondrocyte hypertrophy. J Cell Sci. 2016 Feb 15;129(4):717-28 |
1 | J:270164 Guo M, Du Y, Gokey JJ, Ray S, Bell SM, Adam M, Sudha P, Perl AK, Deshmukh H, Potter SS, Whitsett JA, Xu Y, Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth. Nat Commun. 2019 Jan 3;10(1):37 |
1* | J:332497 Tang X, Wei W, Snowball JM, Nakayasu ES, Bell SM, Ansong C, Lin X, Whitsett JA, EMC3 regulates mesenchymal cell survival via control of the mitotic spindle assembly. iScience. 2023 Jan 20;26(1):105667 |
Atf7ip activating transcription factor 7 interacting protein (Synonyms: 2610204M12Rik, AM, ATFa-associated Modulator, Mcaf1) | |
Results | Reference |
1* | J:61657 De Graeve F, Bahr A, Chatton B, Kedinger C, A murine ATFa-associated factor with transcriptional repressing activity. Oncogene. 2000 Mar 30;19(14):1807-19 |
Atf7ip2 activating transcription factor 7 interacting protein 2 (Synonyms: 4930558K11Rik, Get-1, MGC:6783, PSM2) | |
Results | Reference |
1* | J:121917 Olesen C, Nyeng P, Kalisz M, Jensen TH, Moller M, Tommerup N, Byskov AG, Global gene expression analysis in fetal mouse ovaries with and without meiosis and comparison of selected genes with meiosis in the testis. Cell Tissue Res. 2007 Apr;328(1):207-21 |
Atg5 autophagy related 5 (Synonyms: 2010107M05Rik, 3110067M24Rik, Apg5l, Paddy) | |
Results | Reference |
1 | J:233601 Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP, Harwood CA, Byrne C, O'Shaughnessy RF, Bergamaschi D, Constitutive Autophagy and Nucleophagy during Epidermal Differentiation. J Invest Dermatol. 2016 Jul;136(7):1460-70 |
1 | J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410 |
1* | J:190998 Yang JW, Zhu LX, Yuan GH, Chen YX, Zhang L, Zhang L, Chen Z, Autophagy appears during the development of the mouse lower first molar. Histochem Cell Biol. 2013 Jan;139(1):109-18 |
1 | J:280538 Yeganeh B, Lee J, Ermini L, Lok I, Ackerley C, Post M, Autophagy is required for lung development and morphogenesis. J Clin Invest. 2019 Jun 4;129(7):2904-2919 |
Atg7 autophagy related 7 (Synonyms: 1810013K23Rik, Apg7l) | |
Results | Reference |
1 | J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410 |
1 | J:280538 Yeganeh B, Lee J, Ermini L, Lok I, Ackerley C, Post M, Autophagy is required for lung development and morphogenesis. J Clin Invest. 2019 Jun 4;129(7):2904-2919 |
Atg12 autophagy related 12 (Synonyms: 4931423H11Rik, A330058M13Rik, Apg12l) | |
Results | Reference |
1 | J:233601 Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP, Harwood CA, Byrne C, O'Shaughnessy RF, Bergamaschi D, Constitutive Autophagy and Nucleophagy during Epidermal Differentiation. J Invest Dermatol. 2016 Jul;136(7):1460-70 |
1 | J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410 |
Atg16l1 autophagy related 16 like 1 (Synonyms: 1500009K01Rik, APG16L, WDR30) | |
Results | Reference |
1 | J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410 |
Atic 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (Synonyms: 2610509C24Rik) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Atl2 atlastin GTPase 2 (Synonyms: 2010110I21Rik, Aip-2, Arl6ip2) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Atm ataxia telangiectasia mutated (Synonyms: C030026E19Rik) | |
Results | Reference |
1* | J:49187 Soares HD, Morgan JI, McKinnon PJ, Atm expression patterns suggest a contribution from the peripheral nervous system to the phenotype of ataxia-telangiectasia. Neuroscience. 1998 Oct;86(4):1045-54 |
Atoh1 atonal bHLH transcription factor 1 (Synonyms: bHLHa14, Hath1, Math1) | |
Results | Reference |
2 | J:225514 Ahmed M, Ura K, Streit A, Auditory hair cell defects as potential cause for sensorineural deafness in Wolf-Hirschhorn syndrome. Dis Model Mech. 2015 Sep 1;8(9):1027-35 |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1 | J:60393 Ben-Arie N, Hassan BA, Bermingham NA, Malicki DM, Armstrong D, Matzuk M, Bellen HJ, Zoghbi HY, Functional conservation of atonal and Math1 in the CNS and PNS. Development. 2000 Mar;127(5):1039-48 |
1* | J:35238 Ben-Arie N, McCall AE, Berkman S, Eichele G, Bellen HJ, Zoghbi HY, Evolutionary conservation of sequence and expression of the bHLH protein Atonal suggests a conserved role in neurogenesis. Hum Mol Genet. 1996 Sep;5(9):1207-16 |
1 | J:199162 Cai T, Seymour ML, Zhang H, Pereira FA, Groves AK, Conditional deletion of Atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of Corti. J Neurosci. 2013 Jun 12;33(24):10110-22 |
2* | J:161290 Chizhikov VV, Lindgren AG, Mishima Y, Roberts RW, Aldinger KA, Miesegaes GR, Currle DS, Monuki ES, Millen KJ, Lmx1a regulates fates and location of cells originating from the cerebellar rhombic lip and telencephalic cortical hem. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10725-30 |
1 | J:226819 Coate TM, Spita NA, Zhang KD, Isgrig KT, Kelley MW, Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife. 2015;4 |
1 | J:142229 Dabdoub A, Puligilla C, Jones JM, Fritzsch B, Cheah KS, Pevny LH, Kelley MW, Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18396-401 |
1 | J:215675 Deng M, Luo XJ, Pan L, Yang H, Xie X, Liang G, Huang L, Hu F, Kiernan AE, Gan L, LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea. J Neurosci. 2014 Jul 23;34(30):10072-7 |
1 | J:155885 Dubreuil V, Thoby-Brisson M, Rallu M, Persson K, Pattyn A, Birchmeier C, Brunet JF, Fortin G, Goridis C, Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons. J Neurosci. 2009 Nov 25;29(47):14836-46 |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
1 | J:112207 Englund C, Kowalczyk T, Daza RA, Dagan A, Lau C, Rose MF, Hevner RF, Unipolar brush cells of the cerebellum are produced in the rhombic lip and migrate through developing white matter. J Neurosci. 2006 Sep 6;26(36):9184-95 |
1 | J:184924 Fernandes M, Antoine M, Hebert JM, SMAD4 is essential for generating subtypes of neurons during cerebellar development. Dev Biol. 2012 May 1;365(1):82-90 |
1* | J:87736 Gazit R, Krizhanovsky V, Ben-Arie N, Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway. Development. 2004 Feb;131(4):903-13 |
2 | J:223798 Golden EJ, Benito-Gonzalez A, Doetzlhofer A, The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3864-73 |
1 | J:206577 Green MJ, Myat AM, Emmenegger BA, Wechsler-Reya RJ, Wilson LJ, Wingate RJ, Independently specified Atoh1 domains define novel developmental compartments in rhombomere 1. Development. 2014 Jan;141(2):389-98 |
1 | J:117235 Hayashi T, Cunningham D, Bermingham-McDonogh O, Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti. Dev Dyn. 2007 Feb;236(2):525-33 |
1 | J:130251 Hori K, Cholewa-Waclaw J, Nakada Y, Glasgow SM, Masui T, Henke RM, Wildner H, Martarelli B, Beres TM, Epstein JA, Magnuson MA, Macdonald RJ, Birchmeier C, Johnson JE, A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes Dev. 2008 Jan 15;22(2):166-78 |
1 | J:100997 Hoshino M, Nakamura S, Mori K, Kawauchi T, Terao M, Nishimura YV, Fukuda A, Fuse T, Matsuo N, Sone M, Watanabe M, Bito H, Terashima T, Wright CV, Kawaguchi Y, Nakao K, Nabeshima Y, Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum. Neuron. 2005 Jul 21;47(2):201-13 |
1 | J:188329 Huang WH, Tupal S, Huang TW, Ward CS, Neul JL, Klisch TJ, Gray PA, Zoghbi HY, Atoh1 Governs the Migration of Postmitotic Neurons that Shape Respiratory Effectiveness at Birth and Chemoresponsiveness in Adulthood. Neuron. 2012 Sep 6;75(5):799-809 |
1 | J:98458 Kiernan AE, Pelling AL, Leung KK, Tang AS, Bell DM, Tease C, Lovell-Badge R, Steel KP, Cheah KS, Sox2 is required for sensory organ development in the mammalian inner ear. Nature. 2005 Apr 21;434(7036):1031-5 |
1 | J:169455 Kim D, Ackerman SL, The UNC5C netrin receptor regulates dorsal guidance of mouse hindbrain axons. J Neurosci. 2011 Feb 9;31(6):2167-79 |
1* | J:174506 Lai HC, Klisch TJ, Roberts R, Zoghbi HY, Johnson JE, In vivo neuronal subtype-specific targets of Atoh1 (Math1) in dorsal spinal cord. J Neurosci. 2011 Jul 27;31(30):10859-71 |
1 | J:64091 Louvi A, Wassef M, Ectopic engrailed 1 expression in the dorsal midline causes cell death, abnormal differentiation of circumventricular organs and errors in axonal pathfinding. Development. 2000 Sep;127(18):4061-71 |
1 | J:149981 Maricich SM, Wellnitz SA, Nelson AM, Lesniak DR, Gerling GJ, Lumpkin EA, Zoghbi HY, Merkel cells are essential for light-touch responses. Science. 2009 Jun 19;324(5934):1580-2 |
1 | J:218941 Meier F, Giesert F, Delic S, Faus-Kessler T, Matheus F, Simeone A, Holter SM, Kuhn R, Weisenhorn DM, Wurst W, Prakash N, FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS One. 2014;9(7):e101124 |
1* | J:154915 Morrison KM, Miesegaes GR, Lumpkin EA, Maricich SM, Mammalian Merkel cells are descended from the epidermal lineage. Dev Biol. 2009 Dec 1;336(1):76-83 |
1 | J:188114 Munnamalai V, Hayashi T, Bermingham-McDonogh O, Notch prosensory effects in the Mammalian cochlea are partially mediated by fgf20. J Neurosci. 2012 Sep 12;32(37):12876-84 |
1 | J:143162 Murata J, Tokunaga A, Okano H, Kubo T, Mapping of notch activation during cochlear development in mice: implications for determination of prosensory domain and cell fate diversification. J Comp Neurol. 2006 Jul 20;497(3):502-18 |
1 | J:298271 Nguyen MB, Valdes VJ, Cohen I, Pothula V, Zhao D, Zheng D, Ezhkova E, Dissection of Merkel cell formation in hairy and glabrous skin reveals a common requirement for FGFR2-mediated signalling. Exp Dermatol. 2019 Apr;28(4):374-382 |
1 | J:78879 Pirvola U, Ylikoski J, Trokovic R, Hebert JM, McConnell SK, Partanen J, FGFR1 is required for the development of the auditory sensory epithelium. Neuron. 2002 Aug 15;35(4):671-80 |
1 | J:335097 Qin T, Ho CC, Wang B, Hui CC, Sham MH, Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2206571119 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1 | J:155932 Rose MF, Ahmad KA, Thaller C, Zoghbi HY, Excitatory neurons of the proprioceptive, interoceptive, and arousal hindbrain networks share a developmental requirement for Math1. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22462-7 |
1 | J:155760 Rose MF, Ren J, Ahmad KA, Chao HT, Klisch TJ, Flora A, Greer JJ, Zoghbi HY, Math1 is essential for the development of hindbrain neurons critical for perinatal breathing. Neuron. 2009 Nov 12;64(3):341-54 |
1 | J:286655 Sakamoto S, Tateya T, Omori K, Kageyama R, Id genes are required for morphogenesis and cellular patterning in the developing mammalian cochlea. Dev Biol. 2020 Apr 15;460(2):164-175 |
1 | J:160518 Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, Jenkins RB, Tihan T, Vandenberg SR, James CD, Tanaka K, Taylor MD, Weiss WA, Chesler L, Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010 May 15;24(10):1059-72 |
1 | J:284161 Tateya T, Sakamoto S, Ishidate F, Hirashima T, Imayoshi I, Kageyama R, Three-dimensional live imaging of Atoh1 reveals the dynamics of hair cell induction and organization in the developing cochlea. Development. 2019 Nov 1;146(21):dev177881 |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
1* | J:60428 Wang Q, McEwen DG, Ornitz DM, Subcellular and developmental expression of alternatively spliced forms of fibroblast growth factor 14. Mech Dev. 2000 Feb;90(2):283-7 |
1* | J:105185 Wang VY, Rose MF, Zoghbi HY, Math1 expression redefines the rhombic lip derivatives and reveals novel lineages within the brainstem and cerebellum. Neuron. 2005 Oct 6;48(1):31-43 |
1 | J:361525 Wu M, Jia G, Liu Y, Lou Y, Li Y, Xia M, Li H, Li W, PKM2 controls cochlear development through lactate-dependent transcriptional regulation. Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2410829122 |
1* | J:248783 Xie WR, Jen HI, Seymour ML, Yeh SY, Pereira FA, Groves AK, Klisch TJ, Zoghbi HY, An Atoh1-S193A Phospho-Mutant Allele Causes Hearing Deficits and Motor Impairment. J Neurosci. 2017 Sep 6;37(36):8583-8594 |
1 | J:210443 Yamada M, Seto Y, Taya S, Owa T, Inoue YU, Inoue T, Kawaguchi Y, Nabeshima Y, Hoshino M, Specification of spatial identities of cerebellar neuron progenitors by ptf1a and atoh1 for proper production of GABAergic and glutamatergic neurons. J Neurosci. 2014 Apr 2;34(14):4786-800 |
1 | J:221935 Zhang S, Ross KD, Seidner GA, Gorman MR, Poon TH, Wang X, Keithley EM, Lee PN, Martindale MQ, Joiner WJ, Hamilton BA, Nmf9 Encodes a Highly Conserved Protein Important to Neurological Function in Mice and Flies. PLoS Genet. 2015 Jul;11(7):e1005344 |
Atoh7 atonal bHLH transcription factor 7 (Synonyms: bHLHa13, Math5) | |
Results | Reference |
1 | J:184871 Brzezinski JA 4th, Prasov L, Glaser T, Math5 defines the ganglion cell competence state in a subpopulation of retinal progenitor cells exiting the cell cycle. Dev Biol. 2012 May 15;365(2):395-413 |
1 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1 | J:147448 Ding Q, Chen H, Xie X, Libby RT, Tian N, Gan L, BARHL2 differentially regulates the development of retinal amacrine and ganglion neurons. J Neurosci. 2009 Apr 1;29(13):3992-4003 |
1 | J:94374 Horsford DJ, Nguyen MT, Sellar GC, Kothary R, Arnheiter H, McInnes RR, Chx10 repression of Mitf is required for the maintenance of mammalian neuroretinal identity. Development. 2005 Jan;132(1):177-87 |
1 | J:99244 Kim J, Wu HH, Lander AD, Lyons KM, Matzuk MM, Calof AL, GDF11 controls the timing of progenitor cell competence in developing retina. Science. 2005 Jun 24;308(5730):1927-30 |
1 | J:295965 Miesfeld JB, Ghiasvand NM, Marsh-Armstrong B, Marsh-Armstrong N, Miller EB, Zhang P, Manna SK, Zawadzki RJ, Brown NL, Glaser T, The Atoh7 remote enhancer provides transcriptional robustness during retinal ganglion cell development. Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21690-21700 |
1* | J:260417 Miesfeld JB, Glaser T, Brown NL, The dynamics of native Atoh7 protein expression during mouse retinal histogenesis, revealed with a new antibody. Gene Expr Patterns. 2018 Jan;27:114-121 |
1* | J:268318 Miesfeld JB, Moon MS, Riesenberg AN, Contreras AN, Kovall RA, Brown NL, Rbpj direct regulation of Atoh7 transcription in the embryonic mouse retina. Sci Rep. 2018 Jul 5;8(1):10195 |
1 | J:206963 Orieux G, Picault L, Slembrouck A, Roger JE, Guillonneau X, Sahel JA, Saule S, McPherson JP, Goureau O, Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells. J Neurosci. 2014 Jan 22;34(4):1530-41 |
1 | J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77 |
3 | J:132603 Saul SM, Brzezinski JA 4th, Altschuler RA, Shore SE, Rudolph DD, Kabara LL, Halsey KE, Hufnagel RB, Zhou J, Dolan DF, Glaser T, Math5 expression and function in the central auditory system. Mol Cell Neurosci. 2008 Jan;37(1):153-69 |
1* | J:86669 Yang Z, Ding K, Pan L, Deng M, Gan L, Math5 determines the competence state of retinal ganglion cell progenitors. Dev Biol. 2003 Dec 1;264(1):240-54 |
1 | J:241572 Zhang Q, Zagozewski J, Cheng S, Dixit R, Zhang S, de Melo J, Mu X, Klein WH, Brown NL, Wigle JT, Schuurmans C, Eisenstat DD, Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina. Development. 2017 May 01;144(9):1698-1711 |
Atoh8 atonal bHLH transcription factor 8 (Synonyms: 4933425C05Rik, bHLHa21, Math6, okadin) | |
Results | Reference |
1 | J:137207 Lynn FC, Sanchez L, Gomis R, German MS, Gasa R, Identification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional network. PLoS One. 2008;3(6):e2430 |
1* | J:203454 Rawnsley DR, Xiao J, Lee JS, Liu X, Mericko-Ishizuka P, Kumar V, He J, Basu A, Lu M, Lynn FC, Pack M, Gasa R, Kahn ML, The transcription factor Atonal homolog 8 regulates Gata4 and Friend of Gata-2 during vertebrate development. J Biol Chem. 2013 Aug 23;288(34):24429-40 |
1* | J:113418 Ross MD, Martinka S, Mukherjee A, Sedor JR, Vinson C, Bruggeman LA, Math6 expression during kidney development and altered expression in a mouse model of glomerulosclerosis. Dev Dyn. 2006 Nov;235(11):3102-9 |
1 | J:308784 Tang Q, Xie MY, Zhang YL, Xue RY, Zhu XH, Yang H, Targeted deletion of Atoh8 results in severe hearing loss in mice. Genesis. 2021 Aug 17;:e23442 |
Atp1a1 ATPase, Na+/K+ transporting, alpha 1 polypeptide (Synonyms: Atpa-1) | |
Results | Reference |
1* | J:28939 Crump RG, Askew GR, Wert SE, Lingrel JB, Joiner CH, In situ localization of sodium-potassium ATPase mRNA in developing mouse lung epithelium. Am J Physiol. 1995 Sep;269(3 Pt 1):L299-308 |
1* | J:42864 Dagenais A, Kothary R, Berthiaume Y, The alpha subunit of the epithelial sodium channel in the mouse: developmental regulation of its expression. Pediatr Res. 1997 Sep;42(3):327-34 |
1* | J:18442 Herrera VL, Cova T, Sassoon D, Ruiz-Opazo N, Developmental cell-specific regulation of Na(+)-K(+)-ATPase alpha 1-, alpha 2-, and alpha 3-isoform gene expression. Am J Physiol. 1994 May;266(5 Pt 1):C1301-12 |
1 | J:249431 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ, Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6:e26851 |
1* | J:166987 Kim HM, Wangemann P, Failure of fluid absorption in the endolymphatic sac initiates cochlear enlargement that leads to deafness in mice lacking pendrin expression. PLoS One. 2010;5(11):e14041 |
1 | J:171693 Kim HM, Wangemann P, Epithelial cell stretching and luminal acidification lead to a retarded development of stria vascularis and deafness in mice lacking pendrin. PLoS One. 2011;6(3):e17949 |
1* | J:346057 Lu D, Zhi Y, Su H, Lin X, Lin J, Shi Y, Yi W, Hong C, Zhang T, Fu Z, Chen LY, Zhao Z, Li R, Xu Z, Chen W, Wang N, Xu D, ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells. Cell Rep. 2024 Feb 24;43(3):113818 |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
Atp1a2 ATPase, Na+/K+ transporting, alpha 2 polypeptide (Synonyms: Atpa-3, mKIAA0778) | |
Results | Reference |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1* | J:18442 Herrera VL, Cova T, Sassoon D, Ruiz-Opazo N, Developmental cell-specific regulation of Na(+)-K(+)-ATPase alpha 1-, alpha 2-, and alpha 3-isoform gene expression. Am J Physiol. 1994 May;266(5 Pt 1):C1301-12 |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
Atp1a3 ATPase, Na+/K+ transporting, alpha 3 polypeptide (Synonyms: Atpa-2, MGC:27631, MGC:38713, MGC:38914, MGC:39036) | |
Results | Reference |
1 | J:354179 Bornstein B, Heinemann-Yerushalmi L, Krief S, Adler R, Dassa B, Leshkowitz D, Kim M, Bewick G, Banks RW, Zelzer E, Molecular characterization of the intact mouse muscle spindle using a multi-omics approach. Elife. 2023 Feb 6;12 |
1* | J:18442 Herrera VL, Cova T, Sassoon D, Ruiz-Opazo N, Developmental cell-specific regulation of Na(+)-K(+)-ATPase alpha 1-, alpha 2-, and alpha 3-isoform gene expression. Am J Physiol. 1994 May;266(5 Pt 1):C1301-12 |
Atp1b1 ATPase, Na+/K+ transporting, beta 1 polypeptide (Synonyms: Atpb, Atpb-1, sodium/potassium ATPase beta subunit) | |
Results | Reference |
2* | J:28939 Crump RG, Askew GR, Wert SE, Lingrel JB, Joiner CH, In situ localization of sodium-potassium ATPase mRNA in developing mouse lung epithelium. Am J Physiol. 1995 Sep;269(3 Pt 1):L299-308 |
1 | J:249431 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ, Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6:e26851 |
1* | J:227089 Pirson M, Knoops B, Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617 |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
Atp1b2 ATPase, Na+/K+ transporting, beta 2 polypeptide (Synonyms: Amog, Atpb-2) | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
Atp1b3 ATPase, Na+/K+ transporting, beta 3 polypeptide | |
Results | Reference |
1 | J:249431 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ, Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6:e26851 |
Atp1b4 ATPase Na+/K+ transporting, beta 4 polypeptide (Synonyms: 1110020B02Rik) | |
Results | Reference |
1 | J:95349 Zhao H, Pestov NB, Korneenko TV, Shakhparonov MI, Modyanov NN, Accumulation of beta (m), a structural member of X,K-ATPase beta-subunit family, in nuclear envelopes of perinatal myocytes. Am J Physiol Cell Physiol. 2004 Apr;286(4):C757-67 |
Atp2a2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (Synonyms: 9530097L16Rik, D5Wsu150e, sarco/endoplasmic reticulum Ca2+-ATPase 2, SERCA2, Serca2a, SERCA2B) | |
Results | Reference |
1 | J:155846 de Lange FJ, Moorman AF, Anderson RH, Manner J, Soufan AT, de Gier-de Vries C, Schneider MD, Webb S, van den Hoff MJ, Christoffels VM, Lineage and morphogenetic analysis of the cardiac valves. Circ Res. 2004 Sep 17;95(6):645-54 |
1 | J:192707 He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, Pu WT, Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res. 2012 Feb 3;110(3):406-15 |
1 | J:46473 Ya J, Erdtsieck-Ernste EB, de Boer PA, van Kempen MJ, Jongsma H , Gros D , Moorman AF , Lamers WH, Heart defects in connexin43-deficient mice. Circ Res. 1998 Feb 23;82(3):360-6 |
Atp2b1 ATPase, Ca++ transporting, plasma membrane 1 (Synonyms: 2810442I22Rik, E130111D10Rik, PMCA1) | |
Results | Reference |
1* | J:57237 Zacharias DA, Kappen C, Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse. Biochim Biophys Acta. 1999 Aug 5;1428(2-3):397-405 |
Atp2b2 ATPase, Ca++ transporting, plasma membrane 2 (Synonyms: D6Abb2e, Gena300, jog, PMCA2, Tmy, wms) | |
Results | Reference |
1* | J:57237 Zacharias DA, Kappen C, Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse. Biochim Biophys Acta. 1999 Aug 5;1428(2-3):397-405 |
Atp2b3 ATPase, Ca++ transporting, plasma membrane 3 (Synonyms: 6430519O13Rik, Pmca3) | |
Results | Reference |
1* | J:57237 Zacharias DA, Kappen C, Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse. Biochim Biophys Acta. 1999 Aug 5;1428(2-3):397-405 |
Atp2b4 ATPase, Ca++ transporting, plasma membrane 4 (Synonyms: PMCA4) | |
Results | Reference |
1* | J:57237 Zacharias DA, Kappen C, Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse. Biochim Biophys Acta. 1999 Aug 5;1428(2-3):397-405 |
Atp4b ATPase, H+/K+ exchanging, beta polypeptide (Synonyms: H+,K+-ATPase, H+/K+-ATPase beta, H,K-ATPase-Beta) | |
Results | Reference |
1 | J:292306 Francis R, Guo H, Streutker C, Ahmed M, Yung T, Dirks PB, He HH, Kim TH, Gastrointestinal transcription factors drive lineage-specific developmental programs in organ specification and cancer. Sci Adv. 2019 Dec;5(12):eaax8898 |
2 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
Atp5f1a ATP synthase F1 subunit alpha (Synonyms: Atp5a1, Atpm, D18Ertd206e, Mom2) | |
Results | Reference |
1 | J:326570 Niu W, Spradling AC, Mouse oocytes develop in cysts with the help of nurse cells. Cell. 2022 Jul 7;185(14):2576-2590.e12 |
1 | J:337469 Park A, Kim KE, Park I, Lee SH, Park KY, Jung M, Li X, Sleiman MB, Lee SJ, Kim DS, Kim J, Lim DS, Woo EJ, Lee EW, Han BS, Oh KJ, Lee SC, Auwerx J, Mun JY, Rhee HW, Kim WK, Bae KH, Suh JM, Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice. Nat Commun. 2023 Jun 23;14(1):3746 |
1* | J:305946 Xu M, Yao J, Shi Y, Yi H, Zhao W, Lin X, Yang Z, The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026 |
Atp5f1b ATP synthase F1 subunit beta (Synonyms: Atp5b) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Atp5f1d ATP synthase F1 subunit delta (Synonyms: 0610008F14Rik, 1500000I11Rik, Atp5d) | |
Results | Reference |
1* | J:170267 Chaignat E, Yahya-Graison EA, Henrichsen CN, Chrast J, Schutz F, Pradervand S, Reymond A, Copy number variation modifies expression time courses. Genome Res. 2011 Jan;21(1):106-13 |
Atp5f1e ATP synthase F1 subunit epsilon (Synonyms: 2410043G19Rik, Atp5e) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
Atp5if1 ATP synthase inhibitory factor subunit 1 (Synonyms: Atpif1, If1) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:268424 Nakamura J, Fujikawa M, Yoshida M, IF1, a natural inhibitor of mitochondrial ATP synthase, is not essential for the normal growth and breeding of mice. Biosci Rep. 2013 Sep 17;33(5):e00067 |
Atp5pb ATP synthase peripheral stalk-membrane subunit b (Synonyms: Atp5f1, C76477) | |
Results | Reference |
1* | J:65091 Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP, Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest. 2000 Oct;106(7):847-56 |
Atp5po ATP synthase peripheral stalk subunit OSCP (Synonyms: Atp5o, D12Wsu28e) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Atp6ap2 ATPase, H+ transporting, lysosomal accessory protein 2 (Synonyms: 5730403E06Rik, Atp6ip2, M8-9, (P)RR, renin/prorenin receptor) | |
Results | Reference |
1* | J:218046 Cuffe JS, Walton SL, Steane SE, Singh RR, Simmons DG, Moritz KM, The effects of gestational age and maternal hypoxia on the placental renin angiotensin system in the mouse. Placenta. 2014 Nov;35(11):953-61 |
3 | J:277670 Liu J, Zhou Y, Liu Y, Li L, Chen Y, Liu Y, Feng Y, Yosypiv IV, Song R, Peng H, (Pro)renin receptor regulates lung development via the Wnt/beta-catenin signaling pathway. Am J Physiol Lung Cell Mol Physiol. 2019 Aug 1;317(2):L202-L211 |
Atp6v0a4 ATPase, H+ transporting, lysosomal V0 subunit A4 (Synonyms: Atp6n1b, V-ATPase alpha 4) | |
Results | Reference |
3* | J:320193 Golder ZJ, Karet Frankl FE, Extra-renal locations of the a4 subunit of H(+)ATPase. BMC Cell Biol. 2016 Jul 2;17(1):27 |
1 | J:249431 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ, Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6:e26851 |
2* | J:150394 Jouret F, Auzanneau C, Debaix H, Wada GH, Pretto C, Marbaix E, Karet FE, Courtoy PJ, Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. J Am Soc Nephrol. 2005 Nov;16(11):3235-46 |
1* | J:188593 Norgett EE, Golder ZJ, Lorente-Canovas B, Ingham N, Steel KP, Frankl FE, Atp6v0a4 knockout mouse is a model of distal renal tubular acidosis with hearing loss, with additional extrarenal phenotype. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13775-80 |
1 | J:223640 Vidarsson H, Westergren R, Heglind M, Blomqvist SR, Breton S, Enerback S, The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis. PLoS One. 2009;4(2):e4471 |
Atp6v0d2 ATPase, H+ transporting, lysosomal V0 subunit D2 (Synonyms: 1620401A02Rik) | |
Results | Reference |
1* | J:320193 Golder ZJ, Karet Frankl FE, Extra-renal locations of the a4 subunit of H(+)ATPase. BMC Cell Biol. 2016 Jul 2;17(1):27 |
1 | J:249431 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ, Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6:e26851 |
Atp6v1a ATPase, H+ transporting, lysosomal V1 subunit A (Synonyms: Atp6a1, lysosomal 70kDa, VA68, VPP2) | |
Results | Reference |
1* | J:150394 Jouret F, Auzanneau C, Debaix H, Wada GH, Pretto C, Marbaix E, Karet FE, Courtoy PJ, Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. J Am Soc Nephrol. 2005 Nov;16(11):3235-46 |
1 | J:223640 Vidarsson H, Westergren R, Heglind M, Blomqvist SR, Breton S, Enerback S, The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis. PLoS One. 2009;4(2):e4471 |
Atp6v1b1 ATPase, H+ transporting, lysosomal V1 subunit B1 (Synonyms: Atp6b1, D630030L16Rik, D630039P21Rik, lysosomal 56/58kDa, Vpp-3, Vpp3) | |
Results | Reference |
1 | J:84744 Dou H, Finberg K, Cardell EL, Lifton R, Choo D, Mice lacking the B1 subunit of H+ -ATPase have normal hearing. Hear Res. 2003 Jun;180(1-2):76-84 |
2* | J:320193 Golder ZJ, Karet Frankl FE, Extra-renal locations of the a4 subunit of H(+)ATPase. BMC Cell Biol. 2016 Jul 2;17(1):27 |
1 | J:249431 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ, Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6:e26851 |
1* | J:150394 Jouret F, Auzanneau C, Debaix H, Wada GH, Pretto C, Marbaix E, Karet FE, Courtoy PJ, Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. J Am Soc Nephrol. 2005 Nov;16(11):3235-46 |
1 | J:333405 Kurtzeborn K, Kwon HN, Iaroshenko V, Faisal I, Ambroz M, Jin X, Qureshi T, Kupari J, Ihermann-Hella A, Vaananen J, Tyynismaa H, Bousova I, Park S, Kuure S, Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of MAPK/ERK targets in embryonic kidney. BMC Biol. 2022 May 13;20(1):112 |
1 | J:223640 Vidarsson H, Westergren R, Heglind M, Blomqvist SR, Breton S, Enerback S, The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis. PLoS One. 2009;4(2):e4471 |
Atp6v1b2 ATPase, H+ transporting, lysosomal V1 subunit B2 (Synonyms: Atp6b2, HO57) | |
Results | Reference |
2* | J:150394 Jouret F, Auzanneau C, Debaix H, Wada GH, Pretto C, Marbaix E, Karet FE, Courtoy PJ, Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. J Am Soc Nephrol. 2005 Nov;16(11):3235-46 |
1 | J:333405 Kurtzeborn K, Kwon HN, Iaroshenko V, Faisal I, Ambroz M, Jin X, Qureshi T, Kupari J, Ihermann-Hella A, Vaananen J, Tyynismaa H, Bousova I, Park S, Kuure S, Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of MAPK/ERK targets in embryonic kidney. BMC Biol. 2022 May 13;20(1):112 |
Atp6v1c1 ATPase, H+ transporting, lysosomal V1 subunit C1 (Synonyms: 1700025B18Rik) | |
Results | Reference |
1* | J:150394 Jouret F, Auzanneau C, Debaix H, Wada GH, Pretto C, Marbaix E, Karet FE, Courtoy PJ, Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. J Am Soc Nephrol. 2005 Nov;16(11):3235-46 |
Atp6v1c2 ATPase, H+ transporting, lysosomal V1 subunit C2 (Synonyms: 1110038G14Rik) | |
Results | Reference |
1* | J:320193 Golder ZJ, Karet Frankl FE, Extra-renal locations of the a4 subunit of H(+)ATPase. BMC Cell Biol. 2016 Jul 2;17(1):27 |
1 | J:249431 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ, Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6:e26851 |
Atp6v1d ATPase, H+ transporting, lysosomal V1 subunit D (Synonyms: 1110004P10Rik, Atp6m, lysosomal 34kDa, VATD, Vma8) | |
Results | Reference |
1* | J:320193 Golder ZJ, Karet Frankl FE, Extra-renal locations of the a4 subunit of H(+)ATPase. BMC Cell Biol. 2016 Jul 2;17(1):27 |
Atp6v1e1 ATPase, H+ transporting, lysosomal V1 subunit E1 (Synonyms: 2410029D23Rik, Atp6e, Atp6e2, Atp6v1e, D6Ertd385e, E2, H(+)-ATPase E-like protein, H+ ATPase subunit E, lysosomal 31kDa) | |
Results | Reference |
1* | J:320193 Golder ZJ, Karet Frankl FE, Extra-renal locations of the a4 subunit of H(+)ATPase. BMC Cell Biol. 2016 Jul 2;17(1):27 |
1* | J:150394 Jouret F, Auzanneau C, Debaix H, Wada GH, Pretto C, Marbaix E, Karet FE, Courtoy PJ, Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. J Am Soc Nephrol. 2005 Nov;16(11):3235-46 |
1 | J:223640 Vidarsson H, Westergren R, Heglind M, Blomqvist SR, Breton S, Enerback S, The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis. PLoS One. 2009;4(2):e4471 |
Atp6v1f ATPase, H+ transporting, lysosomal V1 subunit F (Synonyms: 1110004G16Rik) | |
Results | Reference |
1* | J:320193 Golder ZJ, Karet Frankl FE, Extra-renal locations of the a4 subunit of H(+)ATPase. BMC Cell Biol. 2016 Jul 2;17(1):27 |
Atp6v1g1 ATPase, H+ transporting, lysosomal V1 subunit G1 (Synonyms: 1810024D14Rik, Atp6g1, ATP6J, lysosomal 13kDa, VAG1, Vma10) | |
Results | Reference |
1* | J:150394 Jouret F, Auzanneau C, Debaix H, Wada GH, Pretto C, Marbaix E, Karet FE, Courtoy PJ, Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. J Am Soc Nephrol. 2005 Nov;16(11):3235-46 |
1* | J:79288 Murata Y, Sun-Wada GH, Yoshimizu T, Yamamoto A, Wada Y, Futai M, Differential localization of the vacuolar H+ pump with G subunit isoforms (G1 and G2) in mouse neurons. J Biol Chem. 2002 Sep 27;277(39):36296-303 |
1* | J:81717 Sun-Wada GH, Yoshimizu T, Imai-Senga Y, Wada Y, Futai M, Diversity of mouse proton-translocating ATPase: presence of multiple isoforms of the C, d and G subunits. Gene. 2003 Jan 2;302(1-2):147-53 |
Atp6v1g2 ATPase, H+ transporting, lysosomal V1 subunit G2 (Synonyms: 1500002D01Rik, Atp6g2, lysosomal 13kDa, NG38, VAG2) | |
Results | Reference |
1* | J:79288 Murata Y, Sun-Wada GH, Yoshimizu T, Yamamoto A, Wada Y, Futai M, Differential localization of the vacuolar H+ pump with G subunit isoforms (G1 and G2) in mouse neurons. J Biol Chem. 2002 Sep 27;277(39):36296-303 |
1* | J:81717 Sun-Wada GH, Yoshimizu T, Imai-Senga Y, Wada Y, Futai M, Diversity of mouse proton-translocating ATPase: presence of multiple isoforms of the C, d and G subunits. Gene. 2003 Jan 2;302(1-2):147-53 |
Atp6v1g3 ATPase, H+ transporting, lysosomal V1 subunit G3 | |
Results | Reference |
1* | J:320193 Golder ZJ, Karet Frankl FE, Extra-renal locations of the a4 subunit of H(+)ATPase. BMC Cell Biol. 2016 Jul 2;17(1):27 |
1* | J:150394 Jouret F, Auzanneau C, Debaix H, Wada GH, Pretto C, Marbaix E, Karet FE, Courtoy PJ, Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. J Am Soc Nephrol. 2005 Nov;16(11):3235-46 |
1* | J:81717 Sun-Wada GH, Yoshimizu T, Imai-Senga Y, Wada Y, Futai M, Diversity of mouse proton-translocating ATPase: presence of multiple isoforms of the C, d and G subunits. Gene. 2003 Jan 2;302(1-2):147-53 |
Atp8a1 ATPase phospholipid transporting 8A1 (Synonyms: Atp3a2, B230107D19Rik) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Atp9b ATPase, class II, type 9B (Synonyms: IIb) | |
Results | Reference |
1 | J:131661 Rizzolio F, Bione S, Sala C, Tribioli C, Ciccone R, Zuffardi O, di Iorgi N, Maghnie M, Toniolo D, Highly conserved non-coding sequences and the 18q critical region for short stature: a common mechanism of disease?. PLoS One. 2008;3(1):e1460 |
Atp13a2 ATPase type 13A2 (Synonyms: 1110012E06Rik) | |
Results | Reference |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
Atrn attractin (Synonyms: Mgca, mKIAA0548) | |
Results | Reference |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Atrx ATRX, chromatin remodeler (Synonyms: 4833408C14Rik, alpha thalassemia/mental retardation syndrome X-linked, DXHXS6677E, Hp1bp2, HP1-BP38, Rad54, XH2, Xnp) | |
Results | Reference |
2* | J:173600 Huyhn K, Renfree MB, Graves JA, Pask AJ, ATRX has a critical and conserved role in mammalian sexual differentiation. BMC Dev Biol. 2011;11:39 |
1* | J:347585 Leon NY, Le TNU, Garvie A, Wong LH, Bagheri-Fam S, Harley VR, Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. iScience. 2024 May 17;27(5):109629 |
1 | J:203136 Solomon LA, Russell BA, Watson LA, Beier F, Berube NG, Targeted loss of the ATR-X syndrome protein in the limb mesenchyme of mice causes brachydactyly. Hum Mol Genet. 2013 Dec 15;22(24):5015-25 |
Atxn1 ataxin 1 (Synonyms: 2900016G23Rik, Atx1, Sca1) | |
Results | Reference |
1* | J:30900 Banfi S, Servadio A, Chung M, Capozzoli F, Duvick LA, Elde R, Zoghbi HY, Orr HT, Cloning and developmental expression analysis of the murine homolog of the spinocerebellar ataxia type 1 gene (Sca1). Hum Mol Genet. 1996 Jan;5(1):33-40 |
Atxn3 ataxin 3 (Synonyms: 2210008M02Rik, ataxin-3, Atx3, Mjd, MJD1, Sca3) | |
Results | Reference |
1* | J:91583 do Carmo Costa M, Gomes-da-Silva J, Miranda CJ, Sequeiros J, Santos MM, Maciel P, Genomic structure, promoter activity, and developmental expression of the mouse homologue of the Machado-Joseph disease (MJD) gene. Genomics. 2004 Aug;84(2):361-73 |
Atxn7 ataxin 7 (Synonyms: A430107N12Rik, ataxin-7, Sca7) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
Atxn10 ataxin 10 (Synonyms: E46, Sca10, TEG-169, Tex169) | |
Results | Reference |
1* | J:173396 Sang L, Miller JJ, Corbit KC, Giles RH, Brauer MJ, Otto EA, Baye LM, Wen X, Scales SJ, Kwong M, Huntzicker EG, Sfakianos MK, Sandoval W, Bazan JF, Kulkarni P, Garcia-Gonzalo FR, Seol AD, O'Toole JF, Held S, Reutter HM, Lane WS, Rafiq MA, Noor A, Ansar M,Devi AR, Sheffield VC, Slusarski DC, Vincent JB, Doherty DA, Hildebrandt F, Reiter JF, Jackson PK, Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways. Cell. 2011 May 13;145(4):513-28 |
Aurka aurora kinase A (Synonyms: AIRK1, Ark1, aurora A, Aurora-A, Ayk1, IAK, IAK1, Stk6) | |
Results | Reference |
1* | J:205247 Li CC, Chu HY, Yang CW, Chou CK, Tsai TF, Aurora-A overexpression in mouse liver causes p53-dependent premitotic arrest during liver regeneration. Mol Cancer Res. 2009 May;7(5):678-88 |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
1 | J:317613 Patnaik SR, Kretschmer V, Brucker L, Schneider S, Volz AK, Oancea-Castillo LDR, May-Simera HL, Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation. Cell Mol Life Sci. 2019 Feb;76(4):757-775 |
2 | J:83946 Tay J, Hodgman R, Sarkissian M, Richter JD, Regulated CPEB phosphorylation during meiotic progression suggests a mechanism for temporal control of maternal mRNA translation. Genes Dev. 2003 Jun 15;17(12):1457-62 |
1 | J:196491 Torchia EC, Zhang L, Huebner AJ, Sen S, Roop DR, Aurora kinase-A deficiency during skin development impairs cell division and stratification. J Invest Dermatol. 2013 Jan;133(1):78-86 |
2 | J:41165 Yanai A, Arama E, Kilfin G, Motro B, ayk1, a novel mammalian gene related to Drosophila aurora centrosome separation kinase, is specifically expressed during meiosis. Oncogene. 1997 Jun 19;14(24):2943-50 |
Aurkb aurora kinase B (Synonyms: Aik2, AIRK2, aurora B, IPL1, STK-1, Stk12, Stk5) | |
Results | Reference |
1* | J:244087 Stopp S, Grundl M, Fackler M, Malkmus J, Leone M, Naumann R, Frantz S, Wolf E, von Eyss B, Engel FB, Gaubatz S, Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during development. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):8029-8034 |
Auts2 autism susceptibility candidate 2 (Synonyms: 2700063G02Rik, A730011F23Rik, D830032G16Rik) | |
Results | Reference |
1 | J:243531 Hori K, Nagai T, Shan W, Sakamoto A, Taya S, Hashimoto R, Hayashi T, Abe M, Yamazaki M, Nakao K, Nishioka T, Sakimura K, Yamada K, Kaibuchi K, Hoshino M, Cytoskeletal regulation by AUTS2 in neuronal migration and neuritogenesis. Cell Rep. 2014 Dec 24;9(6):2166-79 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Avil advillin (Synonyms: DOC6) | |
Results | Reference |
1* | J:130971 Hasegawa H, Abbott S, Han BX, Qi Y, Wang F, Analyzing somatosensory axon projections with the sensory neuron-specific Advillin gene. J Neurosci. 2007 Dec 26;27(52):14404-14 |
1 | J:52976 Marks PW, Arai M, Bandura JL, Kwiatkowski DJ, Advillin (p92): a new member of the gelsolin/villin family of actin regulatory proteins. J Cell Sci. 1998 Aug;111(Pt 15):2129-36 |
Avp arginine vasopressin (Synonyms: Vp, Vsp) | |
Results | Reference |
2* | J:173124 Aujla PK, Bora A, Monahan P, Sweedler JV, Raetzman LT, The Notch effector gene Hes1 regulates migration of hypothalamic neurons, neuropeptide content and axon targeting to the pituitary. Dev Biol. 2011 May 1;353(1):61-71 |
1* | J:307270 Aulino EA, Caldwell HK, Subtle sex differences in vasopressin mRNA expression in the embryonic mouse brain. J Neuroendocrinol. 2020 Feb;32(2):e12835 |
1 | J:58438 Deiner MS, Sretavan DW, Altered midline axon pathways and ectopic neurons in the developing hypothalamus of netrin-1- and DCC-deficient mice. J Neurosci. 1999 Nov 15;19(22):9900-12 |
1 | J:229100 Goto M, Hojo M, Ando M, Kita A, Kitagawa M, Ohtsuka T, Kageyama R, Miyamoto S, Hes1 and Hes5 are required for differentiation of pituicytes and formation of the neurohypophysis in pituitary development. Brain Res. 2015 Nov 2;1625:206-17 |
1* | J:49030 Jing X, Ratty AK, Murphy D, Ontogeny of the vasopressin and oxytocin RNAs in the mouse hypothalamus. Neurosci Res. 1998 Apr;30(4):343-9 |
1* | J:91307 Korteweg N, Maia AS, Verhage M, Burbach JP, Development of the mouse hypothalamo-neurohypophysial system in the munc18-1 null mutant that lacks regulated secretion. Eur J Neurosci. 2004 Jun;19(11):2944-52 |
1 | J:308477 Madrigal MP, Jurado S, Specification of oxytocinergic and vasopressinergic circuits in the developing mouse brain. Commun Biol. 2021 May 14;4(1):586 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Avpr1a arginine vasopressin receptor 1A (Synonyms: V1aR) | |
Results | Reference |
2* | J:307270 Aulino EA, Caldwell HK, Subtle sex differences in vasopressin mRNA expression in the embryonic mouse brain. J Neuroendocrinol. 2020 Feb;32(2):e12835 |
Avpr2 arginine vasopressin receptor 2 (Synonyms: DI1, ND1, nephrogenic diabetes insipidus, V2R) | |
Results | Reference |
1* | J:151683 Parreira KS, Debaix H, Cnops Y, Geffers L, Devuyst O, Expression patterns of the aquaporin gene family during renal development: influence of genetic variability. Pflugers Arch. 2009 Aug;458(4):745-59 |
Axin1 axin 1 | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
1 | J:173573 Haara O, Fujimori S, Schmidt-Ullrich R, Hartmann C, Thesleff I, Mikkola ML, Ectodysplasin and Wnt pathways are required for salivary gland branching morphogenesis. Development. 2011 Jul;138(13):2681-91 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:41619 Zeng L, Fagotto F, Zhang T, Hsu W, Vasicek TJ, Perry WL 3rd , Lee JJ , Tilghman SM , Gumbiner BM , Costantini F, The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation. Cell. 1997 Jul 11;90(1):181-92 |
1* | J:105879 Zhang TJ, Hoffman BG, Ruiz de Algara T, Helgason CD, SAGE reveals expression of Wnt signalling pathway members during mouse prostate development. Gene Expr Patterns. 2006 Mar;6(3):310-24 |
Axin2 axin 2 (Synonyms: Axil, Conductin) | |
Results | Reference |
1 | J:353312 Adutwum-Ofosu K, Magnani D, Theil T, Price DJ, Fotaki, The molecular and cellular signatures of the mouse eminentia thalami support its role as a signalling centre in the developing forebrain. Brain Struct Funct. 2016;221(7):3709-27 |
1* | J:176498 Al Alam D, Green M, Tabatabai Irani R, Parsa S, Danopoulos S, Sala FG, Branch J, El Agha E, Tiozzo C, Voswinckel R, Jesudason EC, Warburton D, Bellusci S, Contrasting expression of canonical Wnt signaling reporters TOPGAL, BATGAL and Axin2(LacZ) during murine lung development and repair. PLoS One. 2011;6(8):e23139 |
1 | J:290897 Auguste A, Chassot AA, Gregoire EP, Renault L, Pannetier M, Treier M, Pailhoux E, Chaboissier MC, Loss of R-spondin1 and Foxl2 amplifies female-to-male sex reversal in XX mice. Sex Dev. 2011;5(6):304-17 |
1 | J:262819 Bohnenpoll T, Feraric S, Nattkemper M, Weiss AC, Rudat C, Meuser M, Trowe MO, Kispert A, Diversification of Cell Lineages in Ureter Development. J Am Soc Nephrol. 2017 Jun;28(6):1792-1801 |
1 | J:229892 Bosada FM, Devasthali V, Jones KA, Stankunas K, Wnt/beta-catenin signaling enables developmental transitions during valvulogenesis. Development. 2016 Mar 15;143(6):1041-54 |
2* | J:248190 Chen K, Quan H, Chen G, Xiao D, Spatio-temporal expression patterns of Wnt signaling pathway during the development of temporomandibular condylar cartilage. Gene Expr Patterns. 2017 Nov;25-26:149-158 |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
1 | J:176438 Esteve P, Sandonis A, Ibanez C, Shimono A, Guerrero I, Bovolenta P, Secreted frizzled-related proteins are required for Wnt/{beta}-catenin signalling activation in the vertebrate optic cup. Development. 2011 Oct;138(19):4179-84 |
1 | J:312814 Fernandez Vallone V, Leprovots M, Ribatallada-Soriano D, Gerbier R, Lefort A, Libert F, Vassart G, Garcia MI, LGR5 controls extracellular matrix production by stem cells in the developing intestine. EMBO Rep. 2020 Jul 3;21(7):e49224 |
1* | J:150374 Garcia MI, Ghiani M, Lefort A, Libert F, Strollo S, Vassart G, LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine. Dev Biol. 2009 Jul 1;331(1):58-67 |
1 | J:239666 Hagglund AC, Jones I, Carlsson L, A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development. Dis Model Mech. 2017 Mar 01;10(3):245-257 |
2* | J:280430 Janeckova E, Feng J, Li J, Rodriguez G, Chai Y, Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development. PLoS One. 2019;14(10):e0223879 |
1* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
1* | J:154372 Li X, Udager AM, Hu C, Qiao XT, Richards N, Gumucio DL, Dynamic patterning at the pylorus: Formation of an epithelial intestine-stomach boundary in late fetal life. Dev Dyn. 2009 Oct 29;238(12):3205-3217 |
1* | J:175083 Lorenz A, Deutschmann M, Ahlfeld J, Prix C, Koch A, Smits R, Fodde R, Kretzschmar HA, Schuller U, Severe alterations of cerebellar cortical development after constitutive activation of wnt signaling in granule neuron precursors. Mol Cell Biol. 2011 Aug;31(16):3326-38 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:236373 Ludtke TH, Rudat C, Wojahn I, Weiss AC, Kleppa MJ, Kurz J, Farin HF, Moon A, Christoffels VM, Kispert A, Tbx2 and Tbx3 Act Downstream of Shh to Maintain Canonical Wnt Signaling during Branching Morphogenesis of the Murine Lung. Dev Cell. 2016 Oct 24;39(2):239-253 |
1 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
1 | J:264383 Meng Q, Mongan M, Wang J, Xia Y, Repression of MAP3K1 expression and JNK activity by canonical Wnt signaling. Dev Biol. 2018 Aug 15;440(2):129-136 |
1* | J:156970 Mikels A, Minami Y, Nusse R, Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling. J Biol Chem. 2009 Oct 30;284(44):30167-76 |
1 | J:144348 Ohazama A, Johnson EB, Ota MS, Choi HJ, Porntaveetus T, Oommen S, Itoh N, Eto K, Gritli-Linde A, Herz J, Sharpe PT, Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One. 2008;3(12):e4092 |
2 | J:328944 Olbertova K, Hrckulak D, Kriz V, Jesionek W, Kubovciak J, Esner M, Korinek V, Buchtova M, Role of LGR5-positive mesenchymal cells in craniofacial development. Front Cell Dev Biol. 2022;10:810527 |
1* | J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20 |
1 | J:255488 Premarathne S, Murtaza M, Matigian N, Jolly LA, Wood SA, Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors. Sci Rep. 2017 Aug 14;7(1):8109 |
1* | J:190538 Simons BW, Hurley PJ, Huang Z, Ross AE, Miller R, Marchionni L, Berman DM, Schaeffer EM, Wnt signaling though beta-catenin is required for prostate lineage specification. Dev Biol. 2012 Nov 15;371(2):246-55 |
1 | J:361958 Straube P, Beckers A, Jany UWH, Bergmann F, Ludtke TH, Rudat C, Trowe MO, Peters I, Klopf MG, Mamo TM, Kispert A, Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter. Development. 2025 Feb 1;152(3) |
2* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
2 | J:311811 Trowe MO, Airik R, Weiss AC, Farin HF, Foik AB, Bettenhausen E, Schuster-Gossler K, Taketo MM, Kispert A, Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter. Development. 2012 Sep;139(17):3099-108 |
1 | J:332922 Venkata VD, Jamaluddin MFB, Goad J, Drury HR, Tadros MA, Lim R, Karakoti A, O'Sullivan R, Ius Y, Jaaback K, Nahar P, Tanwar PS, Development and characterization of human fetal female reproductive tract organoids to understand Mullerian duct anomalies. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2118054119 |
1* | J:146829 Yamada W, Nagao K, Horikoshi K, Fujikura A, Ikeda E, Inagaki Y, Kakitani M, Tomizuka K, Miyazaki H, Suda T, Takubo K, Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun. 2009 Apr 10;381(3):453-8 |
1 | J:98523 Yu HM, Jerchow B, Sheu TJ, Liu B, Costantini F, Puzas JE, Birchmeier W, Hsu W, The role of Axin2 in calvarial morphogenesis and craniosynostosis. Development. 2005 Apr;132(8):1995-2005 |
1 | J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687 |
Axl AXL receptor tyrosine kinase (Synonyms: Ark, Tyro7, Ufo) | |
Results | Reference |
1* | J:1480 Faust M, Ebensperger C, Schulz AS, Schleithoff L, Hameister H, Bartram CR, Janssen JW, The murine ufo receptor: molecular cloning, chromosomal localization and in situ expression analysis. Oncogene. 1992 Jul;7(7):1287-93 |
AY074887 cDNA sequence AY074887 (Synonyms: cleft palate-related protein 1, Mcpr1) | |
Results | Reference |
1* | J:83857 Xuan DY, Li X, Deng ZH, Zhang HL, Feng P, Duan XY, Jin Y, Identification and characterization of a novel gene, Mcpr1, and its possible function in the proliferation of embryonic palatal mesenchymal cells. J Biol Chem. 2006;281(45):33997-34008 |
B2m beta-2 microglobulin (Synonyms: beta2-m, beta 2 microglobulin, Ly-m11) | |
Results | Reference |
1 | J:66029 Gouble A, Morello D, Synchronous and regulated expression of two AU-binding proteins, AUF1 and HuR, throughout murine development. Oncogene. 2000 Nov 9;19(47):5377-84 |
1* | J:110815 Lau AL, Kumar TR, Nishimori K, Bonadio J, Matzuk MM, Activin betaC and betaE genes are not essential for mouse liver growth, differentiation, and regeneration. Mol Cell Biol. 2000 Aug;20(16):6127-37 |
B3galnt1 UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1 (Synonyms: B3galt3, Brainiac 1, Globoside blood group, Mbrn 1) | |
Results | Reference |
1 | J:70591 Vollrath B, Fitzgerald KJ, Leder P, A Murine Homologue of the Drosophila brainiac Gene Shows Homology to Glycosyltransferases and Is Required for Preimplantation Development of the Mouse. Mol Cell Biol. 2001 Aug;21(16):5688-97 |
B3gat1 beta-1,3-glucuronyltransferase 1 (Synonyms: 0710007K08Rik, GlcAT-P) | |
Results | Reference |
1 | J:237540 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R, The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development. 2016 Nov 15;143(22):4182-4192 |
B130002B16Rik Riken cDNA B130002B16 gene | |
Results | Reference |
1* | J:208246 Han Z, Liu Q, Huang Z, Cui W, Tian Y, Yan W, Wu Q, Expression and imprinting analysis of AK044800, a transcript from the Dlk1-Dio3 imprinted gene cluster during mouse embryogenesis. Mol Cells. 2013 Apr;35(4):285-90 |
B130021B11Rik RIKEN cDNA B130021B11 gene | |
Results | Reference |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
B830012L14Rik RIKEN cDNA B830012L14 gene | |
Results | Reference |
1* | J:177403 Zhang FW, Zeng TB, Han ZB, He HJ, Chen Y, Gu N, Jiang HJ, Wu Q, Imprinting and expression analysis of a non-coding RNA gene in the mouse Dlk1-Dio3 domain. J Mol Histol. 2011 Aug;42(4):333-9 |
Bace1 beta-site APP cleaving enzyme 1 | |
Results | Reference |
1 | J:316129 Login H, Butowt R, Bohm S, Activity-dependent and graded BACE1 expression in the olfactory epithelium is mediated by the retinoic acid metabolizing enzyme CYP26B1. Brain Struct Funct. 2015 Jul;220(4):2143-57 |
Bad BCL2-associated agonist of cell death (Synonyms: Bbc2) | |
Results | Reference |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
2* | J:358134 Soma S, Murakami K, Fukuchi Y, Kunimoto H, Nakajima H, O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. Stem Cells. 2024 Jan 13;42(1):55-63 |
Bahcc1 BAH domain and coiled-coil containing 1 (Synonyms: MGC:79150) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Bak1 BCL2-antagonist/killer 1 (Synonyms: Bak, N-Bak) | |
Results | Reference |
2 | J:297779 Lin L, Zhang M, Stoilov P, Chen L, Zheng S, Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon. Neuron. 2020 Sep 23;107(6):1180-1196.e8 |
Bambi BMP and activin membrane-bound inhibitor (Synonyms: 2610003H06Rik) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
1* | J:67309 Grotewold L, Plum M, Dildrop R, Peters T, Ruther U, Bambi is coexpressed with Bmp-4 during mouse embryogenesis. Mech Dev. 2001 Feb;100(2):327-30 |
Barhl1 BarH like homeobox 1 (Synonyms: Dres115, MBH2) | |
Results | Reference |
1* | J:62505 Bulfone A, Menguzzato E, Broccoli V, Marchitiello A, Gattuso C, Mariani M, Consalez GG, Martinez S, Ballabio A, Banfi S, Barhl1, a gene belonging to a new subfamily of mammalian homeobox genes, is expressed in migrating neurons of the CNS. Hum Mol Genet. 2000 May 22;9(9):1443-52 |
1 | J:193244 Di Meglio T, Kratochwil CF, Vilain N, Loche A, Vitobello A, Yonehara K, Hrycaj SM, Roska B, Peters AH, Eichmann A, Wellik D, Ducret S, Rijli FM, Ezh2 orchestrates topographic migration and connectivity of mouse precerebellar neurons. Science. 2013 Jan 11;339(6116):204-7 |
2* | J:278498 Friocourt F, Kozulin P, Belle M, Suarez R, Di-Poi N, Richards LJ, Giacobini P, Chedotal A, Shared and differential features of Robo3 expression pattern in amniotes. J Comp Neurol. 2019 Aug 15;527(12):2009-2029 |
1 | J:169455 Kim D, Ackerman SL, The UNC5C netrin receptor regulates dorsal guidance of mouse hindbrain axons. J Neurosci. 2011 Feb 9;31(6):2167-79 |
1* | J:107595 Landsberg RL, Awatramani RB, Hunter NL, Farago AF, DiPietrantonio HJ, Rodriguez CI, Dymecki SM, Hindbrain rhombic lip is comprised of discrete progenitor cell populations allocated by Pax6. Neuron. 2005 Dec 22;48(6):933-47 |
1* | J:77122 Li S, Price SM, Cahill H, Ryugo DK, Shen MM, Xiang M, Hearing loss caused by progressive degeneration of cochlear hair cells in mice deficient for the Barhl1 homeobox gene. Development. 2002 Jul;129(14):3523-32 |
1 | J:96912 Li S, Qiu F, Xu A, Price SM, Xiang M, Barhl1 regulates migration and survival of cerebellar granule cells by controlling expression of the neurotrophin-3 gene. J Neurosci. 2004 Mar 24;24(12):3104-14 |
1 | J:143462 Liu Z, Li H, Hu X, Yu L, Liu H, Han R, Colella R, Mower GD, Chen Y, Qiu M, Control of precerebellar neuron development by Olig3 bHLH transcription factor. J Neurosci. 2008 Oct 1;28(40):10124-33 |
1 | J:306314 Maheshwari U, Kraus D, Vilain N, Holwerda SJB, Cankovic V, Maiorano NA, Kohler H, Satoh D, Sigrist M, Arber S, Kratochwil CF, Di Meglio T, Ducret S, Rijli FM, Postmitotic Hoxa5 Expression Specifies Pontine Neuron Positional Identity and Input Connectivity of Cortical Afferent Subsets. Cell Rep. 2020 Jun 16;31(11):107767 |
2 | J:293331 Martinez-Chavez E, Scheerer C, Wizenmann A, Blaess S, The zinc-finger transcription factor GLI3 is a regulator of precerebellar neuronal migration. Development. 2018 Dec 17;145(24):dev166033 |
1 | J:348685 Masuda A, Nishida K, Ajima R, Saga Y, Bakhtan M, Klar A, Hirata T, Zhu Y, A global gene regulatory program and its region-specific regulator partition neurons into commissural and ipsilateral projection types. Sci Adv. 2024 May 24;10(21):eadk2149 |
2* | J:89191 Mo Z, Li S, Yang X, Xiang M, Role of the Barhl2 homeobox gene in the specification of glycinergic amacrine cells. Development. 2004 Apr;131(7):1607-18 |
1 | J:171288 Nishida K, Nakayama K, Yoshimura S, Murakami F, Role of Neph2 in pontine nuclei formation in the developing hindbrain. Mol Cell Neurosci. 2011 Mar;46(3):662-70 |
1 | J:283382 Qin L, Ahn KJ, Wine Lee L, de Charleroy C Jr, Crenshaw EB 3rd, Analyses with double knockouts of the Bmpr1a and Bmpr1b genes demonstrate that BMP signaling is involved in the formation of precerebellar mossy fiber nuclei derived from the rhombic lip. PLoS One. 2019;14(12):e0226602 |
1 | J:218606 Zelina P, Blockus H, Zagar Y, Peres A, Friocourt F, Wu Z, Rama N, Fouquet C, Hohenester E, Tessier-Lavigne M, Schweitzer J, Roest Crollius H, Chedotal A, Signaling switch of the axon guidance receptor Robo3 during vertebrate evolution. Neuron. 2014 Dec 17;84(6):1258-72 |
2 | J:294199 Zhu Y, Hirata T, Mackay F, Murakami F, Chemokine receptor CXCR7 non-cell-autonomously controls pontine neuronal migration and nucleus formation. Sci Rep. 2020 Jul 16;10(1):11830 |
2 | J:149543 Zhu Y, Matsumoto T, Mikami S, Nagasawa T, Murakami F, SDF1/CXCR4 signalling regulates two distinct processes of precerebellar neuronal migration and its depletion leads to abnormal pontine nuclei formation. Development. 2009 Jun;136(11):1919-28 |
Barhl2 BarH like homeobox 2 (Synonyms: E130309B19Rik, MBH1) | |
Results | Reference |
1 | J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489 |
1 | J:354849 Wutikeli H, Yu Y, Zhang T, Cao J, Nawy S, Shen Y, Role of Elavl-like RNA-binding protein in retinal development and signal transduction. Biochim Biophys Acta Mol Basis Dis. 2024 Sep 20;1871(1):167518 |
Barx1 BarH-like homeobox 1 | |
Results | Reference |
1* | J:46754 Mitsiadis TA, Mucchielli ML, Raffo S, Proust JP, Koopman P, Goridis C, Expression of the transcription factors Otlx2, Barx1 and Sox9 during mouse odontogenesis. Eur J Oral Sci. 1998 Jan;106 Suppl 1:112-6 |
1 | J:43528 Mucchielli ML, Mitsiadis TA, Raffo S, Brunet JF, Proust JP, Goridis C, Mouse Otlx2/RIEG expression in the odontogenic epithelium precedes tooth initiation and requires mesenchyme-derived signals for its maintenance. Dev Biol. 1997 Sep 15;189(2):275-84 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
3 | J:137641 Stringer EJ, Pritchard CA, Beck F, Cdx2 initiates histodifferentiation of the midgut endoderm. FEBS Lett. 2008 Jul 23;582(17):2555-60 |
2* | J:26186 Tissier-Seta JP, Mucchielli ML, Mark M, Mattei MG, Goridis C, Brunet JF, Barx1, a new mouse homeodomain transcription factor expressed in cranio-facial ectomesenchyme and the stomach. Mech Dev. 1995 May;51(1):3-15 |
1 | J:149542 Wang XP, O'Connell DJ, Lund JJ, Saadi I, Kuraguchi M, Turbe-Doan A, Cavallesco R, Kim H, Park PJ, Harada H, Kucherlapati R, Maas RL, Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood. Development. 2009 Jun;136(11):1939-49 |
Barx2 BarH-like homeobox 2 (Synonyms: 2310006E12Rik, Barx2b) | |
Results | Reference |
1* | J:199186 Juuri E, Saito K, Lefebvre S, Michon F, Establishment of crown-root domain borders in mouse incisor. Gene Expr Patterns. 2013 Oct;13(7):255-64 |
2 | J:175540 Tsau C, Ito M, Gromova A, Hoffman MP, Meech R, Makarenkova HP, Barx2 and Fgf10 regulate ocular glands branching morphogenesis by controlling extracellular matrix remodeling. Development. 2011 Aug;138(15):3307-17 |
Bax BCL2-associated X protein | |
Results | Reference |
1 | J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82 |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
1 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1 | J:261834 Maskell LJ, Qamar K, Babakr AA, Hawkins TA, Heads RJ, Budhram-Mahadeo VS, Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart. Cell Death Dis. 2017 Jun 8;8(6):e2861 |
1 | J:97328 Nishio S, Hatano M, Nagata M, Horie S, Koike T, Tokuhisa T, Mochizuki T, Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation. J Clin Invest. 2005 Apr 1;115(4):910-918 |
2* | J:358134 Soma S, Murakami K, Fukuchi Y, Kunimoto H, Nakajima H, O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. Stem Cells. 2024 Jan 13;42(1):55-63 |
1 | J:185290 Song XF, Ren H, Andreasen A, Thomsen JS, Zhai XY, Expression of Bcl-2 and Bax in mouse renal tubules during kidney development. PLoS One. 2012;7(2):e32771 |
Baz1b bromodomain adjacent to zinc finger domain, 1B (Synonyms: Wbscr9, WSTF) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
BB283400 expressed sequence BB283400 (Synonyms: Rncr4) | |
Results | Reference |
1 | J:223034 Krol J, Krol I, Alvarez CP, Fiscella M, Hierlemann A, Roska B, Filipowicz W, A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture. Nat Commun. 2015;6:7305 |
Bbc3 BCL2 binding component 3 (Synonyms: PUMA) | |
Results | Reference |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
1 | J:206929 Watson LA, Wang X, Elbert A, Kernohan KD, Galjart N, Berube NG, Dual Effect of CTCF Loss on Neuroprogenitor Differentiation and Survival. J Neurosci. 2014 Feb 19;34(8):2860-70 |
Bbs2 Bardet-Biedl syndrome 2 (Synonyms: 2410125H22Rik) | |
Results | Reference |
1 | J:94467 Nishimura DY, Fath M, Mullins RF, Searby C, Andrews M, Davis R, Andorf JL, Mykytyn K, Swiderski RE, Yang B, Carmi R, Stone EM, Sheffield VC, Bbs2-null mice have neurosensory deficits, a defect in social dominance, and retinopathy associated with mislocalization of rhodopsin. Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16588-93 |
Bbs9 Bardet-Biedl syndrome 9 (Synonyms: E130103I17Rik, EST 3159894) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Bbx bobby sox HMG box containing (Synonyms: 5530401J07Rik, 5730403O13Rik) | |
Results | Reference |
1 | J:339059 Ihn HJ, Kim JA, Lim J, Nam SH, Hwang SH, Kim YK, Kim JY, Kim JE, Cho ES, Jiang R, Park EK, Bobby sox homolog regulates tooth root formation through modulation of dentin sialophosphoprotein. J Cell Physiol. 2021 Jan;236(1):480-488 |
BC002059 cDNA sequence BC002059 (Synonyms: MGC:6110) | |
Results | Reference |
1* | J:331896 Huang J, Jiang B, Li GW, Zheng D, Li M, Xie X, Pan Y, Wei M, Liu X, Jiang X, Zhang X, Yang L, Bao L, Wang B, m(6)A-modified lincRNA Dubr is required for neuronal development by stabilizing YTHDF1/3 and facilitating mRNA translation. Cell Rep. 2022 Nov 22;41(8):111693 |
BC005537 cDNA sequence BC005537 (Synonyms: 8030460C05Rik, MGC:7474) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Bcam basal cell adhesion molecule (Synonyms: 1200005K12Rik, B-CAM, Lu) | |
Results | Reference |
1* | J:84903 Bolcato-Bellemin AL, Lefebvre O, Arnold C, Sorokin L, Miner JH, Kedinger M, Simon-Assmann P, Laminin alpha5 chain is required for intestinal smooth muscle development. Dev Biol. 2003 Aug 15;260(2):376-90 |
1 | J:71478 Moulson CL, Li C, Miner JH, Localization of Lutheran, a novel laminin receptor, in normal, knockout, and transgenic mice suggests an interaction with laminin alpha5 in vivo. Dev Dyn. 2001 Sep;222(1):101-14 |
1* | J:327425 Soffer A, Mahly A, Padmanabhan K, Cohen J, Adir O, Loushi E, Fuchs Y, Williams SE, Luxenburg C, Apoptosis and tissue thinning contribute to symmetric cell division in the developing mouse epidermis in a nonautonomous way. PLoS Biol. 2022 Aug;20(8):e3001756 |
Bcan brevican (Synonyms: Cspg7) | |
Results | Reference |
1 | J:265822 Chapman H, Riesenberg A, Ehrman LA, Kohli V, Nardini D, Nakafuku M, Campbell K, Waclaw RR, Gsx transcription factors control neuronal versus glial specification in ventricular zone progenitors of the mouse lateral ganglionic eminence. Dev Biol. 2018 Oct 1;442(1):115-126 |
Bcar1 breast cancer anti-estrogen resistance 1 (Synonyms: Cas, Crkas, p130Cas) | |
Results | Reference |
1 | J:339438 Wong W, Estep JA, Treptow AM, Rajabli N, Jahncke JN, Ubina T, Wright KM, Riccomagno MM, An adhesion signaling axis involving Dystroglycan, beta1-Integrin, and Cas adaptor proteins regulates the establishment of the cortical glial scaffold. PLoS Biol. 2023 Aug;21(8):e3002212 |
Bcas1 brain enriched myelin associated protein 1 (Synonyms: 2210416M21Rik, 9030223A09Rik, breast carcinoma amplified sequence 1, NABC1) | |
Results | Reference |
1* | J:337458 Waldhauser V, Baroti T, Frob F, Wegner M, PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12) |
Bcas2 BCAS2 pre-mRNA processing factor (Synonyms: 6430539P16Rik, breast carcinoma amplified sequence 2, C76366, MGC:7712) | |
Results | Reference |
1 | J:353355 Yao X, Wang C, Yu W, Sun L, Lv Z, Xie X, Tian S, Yan L, Li L, Liu J, BCAS2 regulates oocyte meiotic prophase I by participating in mRNA alternative splicing. FASEB J. 2024 Jan;38(1):e23361 |
Bcat1 branched chain aminotransferase 1, cytosolic (Synonyms: Bcat-1, BCATc, Eca39) | |
Results | Reference |
1* | J:117809 Castellano S, Casarosa S, Sweatt AJ, Hutson SM, Bozzi Y, Expression of cytosolic branched chain aminotransferase (BCATc) mRNA in the developing mouse brain. Gene Expr Patterns. 2007 Feb;7(4):485-90 |
1* | J:355649 Li Q, Jiang S, Lei K, Han H, Chen Y, Lin W, Xiong Q, Qi X, Gan X, Sheng R, Wang Y, Zhang Y, Ma J, Li T, Lin S, Zhou C, Chen D, Yuan Q, Metabolic rewiring during bone development underlies tRNA m7G-associated primordial dwarfism. J Clin Invest. 2024 Sep 10;134(20) |
Bckdha branched chain ketoacid dehydrogenase E1, alpha polypeptide (Synonyms: BCKAD E1[a]) | |
Results | Reference |
1* | J:48080 Doering CB, Coursey C, Spangler W, Danner DJ, Murine branched chain alpha-ketoacid dehydrogenase kinase; cDNA cloning, tissue distribution, and temporal expression during embryonic development. Gene. 1998 Jun 8;212(2):213-9 |
Bckdhb branched chain ketoacid dehydrogenase E1, beta polypeptide | |
Results | Reference |
1* | J:48080 Doering CB, Coursey C, Spangler W, Danner DJ, Murine branched chain alpha-ketoacid dehydrogenase kinase; cDNA cloning, tissue distribution, and temporal expression during embryonic development. Gene. 1998 Jun 8;212(2):213-9 |
Bckdk branched chain ketoacid dehydrogenase kinase (Synonyms: BCKD-kinase) | |
Results | Reference |
1* | J:48080 Doering CB, Coursey C, Spangler W, Danner DJ, Murine branched chain alpha-ketoacid dehydrogenase kinase; cDNA cloning, tissue distribution, and temporal expression during embryonic development. Gene. 1998 Jun 8;212(2):213-9 |
Bcl2 B cell leukemia/lymphoma 2 (Synonyms: Bcl-2, C430015F12Rik, D830018M01Rik) | |
Results | Reference |
1* | J:38306 Chen DF, Schneider GE, Martinou JC, Tonegawa S, Bcl-2 promotes regeneration of severed axons in mammalian CNS [see comments]. Nature. 1997 Jan 30;385(6615):434-9 |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
1 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1* | J:60156 Lee K, Lanske B, Karaplis AC, Deeds JD, Kohno H, Nissenson RA, Kronenberg HM, Segre GV, Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development. Endocrinology. 1996 Nov;137(11):5109-18 |
1 | J:16873 Merry DE, Veis DJ, Hickey WF, Korsmeyer SJ, bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS. Development. 1994 Feb;120(2):301-11 |
1 | J:97328 Nishio S, Hatano M, Nagata M, Horie S, Koike T, Tokuhisa T, Mochizuki T, Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation. J Clin Invest. 2005 Apr 1;115(4):910-918 |
2* | J:19108 Novack DV, Korsmeyer SJ, Bcl-2 protein expression during murine development [see comments]. Am J Pathol. 1994 Jul;145(1):61-73 |
1 | J:185290 Song XF, Ren H, Andreasen A, Thomsen JS, Zhai XY, Expression of Bcl-2 and Bax in mouse renal tubules during kidney development. PLoS One. 2012;7(2):e32771 |
1* | J:14432 Veis DJ, Sentman CL, Bach EA, Korsmeyer SJ, Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes. J Immunol. 1993 Sep 1;151(5):2546-54 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Bcl2l1 BCL2-like 1 (Synonyms: bcl-x, BclX, Bcl(X)L, Bcl-XL, Bcl-Xs) | |
Results | Reference |
1* | J:317552 Casey SC, Blumberg B, The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver. Mol Endocrinol. 2012 Jun;26(6):916-25 |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
1 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1 | J:97328 Nishio S, Hatano M, Nagata M, Horie S, Koike T, Tokuhisa T, Mochizuki T, Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation. J Clin Invest. 2005 Apr 1;115(4):910-918 |
2* | J:358134 Soma S, Murakami K, Fukuchi Y, Kunimoto H, Nakajima H, O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. Stem Cells. 2024 Jan 13;42(1):55-63 |
Bcl2l2 BCL2-like 2 (Synonyms: bclw, Bcl-w, Gtrgal2, Gtrosa41) | |
Results | Reference |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
Bcl6 B cell leukemia/lymphoma 6 (Synonyms: Bcl5) | |
Results | Reference |
1* | J:29534 Fukuda T, Miki T, Yoshida T, Hatano M, Ohashi K, Hirosawa S, Tokuhisa T, The murine BCL6 gene is induced in activated lymphocytes as an immediate early gene. Oncogene. 1995 Oct 19;11(8):1657-63 |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:182938 Sevilla LM, Bayo P, Latorre V, Sanchis A, Perez P, Glucocorticoid receptor regulates overlapping and differential gene subsets in developing and adult skin. Mol Endocrinol. 2010 Nov;24(11):2166-78 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
1 | J:197487 Tiberi L, van den Ameele J, Dimidschstein J, Piccirilli J, Gall D, Herpoel A, Bilheu A, Bonnefont J, Iacovino M, Kyba M, Bouschet T, Vanderhaeghen P, BCL6 controls neurogenesis through Sirt1-dependent epigenetic repression of selective Notch targets. Nat Neurosci. 2012 Dec;15(12):1627-35 |
1* | J:36625 Yoshida T, Fukuda T, Okabe S, Hatano M, Miki T, Hirosawa S, Miyasaka N, Isono K, Tokuhisa T, The BCL6 gene is predominantly expressed in keratinocytes at their terminal differentiation stage. Biochem Biophys Res Commun. 1996 Nov 1;228(1):216-20 |
Bcl7a B cell CLL/lymphoma 7A (Synonyms: 4432415N06Rik) | |
Results | Reference |
1 | J:338889 Siguero-Alvarez M, Salguero-Jimenez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sanchez-Saez F, Pineiro-Sabaris R, Felipe-Medina N, Torroja C, Gomez MJ, Sabater-Molina M, Escriba R, Richaud-Patin I, Iglesias-Garcia O, Sbroggio M, Callejas S, O'Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibanez B, Monserrat L, Perez-Pomares JM, Sanchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL, A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation. 2023 Jan 3;147(1):47-65 |
1 | J:279171 Wischhof L, Maida S, Piazzesi A, Gioran A, Barragan Sanz K, Irsen S, Beyer M, Schultze JL, Dyer MJ, Salomoni P, Ehninger D, Nicotera P, Bano D, The SWI/SNF subunit Bcl7a contributes to motor coordination and Purkinje cell function. Sci Rep. 2017 Dec 6;7(1):17055 |
Bcl11a BCL11 transcription factor A (Synonyms: 2810047E18Rik, COUP-TF interacting protein 1, CTIP1, D930021L15Rik, Evi9, Evi9a, Evi9b, Evi9c, mKIAA1809, mouse myeloid leukemia gene) | |
Results | Reference |
1* | J:271614 Gudmundsdottir B, Gudmundsson KO, Klarmann KD, Singh SK, Sun L, Singh S, Du Y, Coppola V, Stockwin L, Nguyen N, Tessarollo L, Thorsteinsson L, Sigurjonsson OE, Gudmundsson S, Rafnar T, Tisdale JF, Keller JR, POGZ Is Required for Silencing Mouse Embryonic beta-like Hemoglobin and Human Fetal Hemoglobin Expression. Cell Rep. 2018 Jun 12;23(11):3236-3248 |
1* | J:255485 Li S, Teegarden A, Bauer EM, Choi J, Messaddeq N, Hendrix DA, Ganguli-Indra G, Leid M, Indra AK, Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development. Sci Rep. 2017 Oct 18;7(1):13427 |
1* | J:245204 Rashid M, Belmont J, Carpenter D, Turner CE, Olson EC, Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation. Development. 2017 Nov 01;144(21):4002-4014 |
1 | J:336152 Rashid M, Olson EC, Delayed cortical development in mice with a neural specific deletion of beta1 integrin. Front Neurosci. 2023;17:1158419 |
1 | J:239331 Smith EC, Luc S, Croney DM, Woodworth MB, Greig LC, Fujiwara Y, Nguyen M, Sher F, Macklis JD, Bauer DE, Orkin SH, Strict in vivo specificity of the Bcl11a erythroid enhancer. Blood. 2016 Oct 05;128(19):2338-2342 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1 | J:227426 Wiegreffe C, Simon R, Peschkes K, Kling C, Strehle M, Cheng J, Srivatsa S, Liu P, Jenkins NA, Copeland NG, Tarabykin V, Britsch S, Bcl11a (Ctip1) Controls Migration of Cortical Projection Neurons through Regulation of Sema3c. Neuron. 2015 Jul 15;87(2):311-25 |
1 | J:235394 Woodworth MB, Greig LC, Liu KX, Ippolito GC, Tucker HO, Macklis JD, Ctip1 Regulates the Balance between Specification of Distinct Projection Neuron Subtypes in Deep Cortical Layers. Cell Rep. 2016 May 3;15(5):999-1012 |
Bcl11b B cell leukemia/lymphoma 11B (Synonyms: 9130430L19Rik, B630002E05Rik, COUP-TF interacting protein 2, CTIP2, Rit1) | |
Results | Reference |
1 | J:344365 Abad C, Robayo MC, Muniz-Moreno MDM, Bernardi MT, Otero MG, Kosanovic C, Griswold AJ, Pierson TM, Walz K, Young JI, Gatad2b, associated with the neurodevelopmental syndrome GAND, plays a critical role in neurodevelopment and cortical patterning. Transl Psychiatry. 2024 Jan 18;14(1):33 |
1 | J:306383 Ahmed R, Sarwar S, Hu J, Cardin V, Qiu LR, Zapata G, Vandeleur L, Yan K, Lerch JP, Corbett MA, Gecz J, Picketts DJ, Transgenic mice with an R342X mutation in Phf6 display clinical features of Borjeson-Forssman-Lehmann Syndrome. Hum Mol Genet. 2021 May 12;30(7):575-594 |
1 | J:339612 Altounian M, Bellon A, Mann F, Neuronal miR-17-5p contributes to interhemispheric cortical connectivity defects induced by prenatal alcohol exposure. Cell Rep. 2023 Aug 22;42(9):113020 |
1 | J:299451 Atkins A, Xu MJ, Li M, Rogers NP, Pryzhkova MV, Jordan PW, SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. Elife. 2020 Nov 17;9:e61171 |
1 | J:356256 Bertino F, Mukherjee D, Bonora M, Bagowski C, Nardelli J, Metani L, Zanin Venturini DI, Chianese D, Santander N, Salaroglio IC, Hentschel A, Quarta E, Genova T, McKinney AA, Allocco AL, Fiorito V, Petrillo S, Ammirata G, De Giorgio F, Dennis E, Allington G, Maier F, Shoukier M, Gloning KP, Munaron L, Mussano F, Salsano E, Pareyson D, di Rocco M, Altruda F, Panagiotakos G, Kahle KT, Gressens P, Riganti C, Pinton PP, Roos A, Arnold T, Tolosano E, Chiabrando D, Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus. Cell Rep Med. 2024 Jul 16;5(7):101647 |
1 | J:203970 Betancourt J, Katzman S, Chen B, Nuclear factor one B regulates neural stem cell differentiation and axonal projection of corticofugal neurons. J Comp Neurol. 2014 Jan 1;522(1):6-35 |
1 | J:316182 Blume M, Inoguchi F, Sugiyama T, Owada Y, Osumi N, Aimi Y, Taki K, Katsuyama Y, Dab1 contributes differently to the morphogenesis of the hippocampal subdivisions. Dev Growth Differ. 2017 Oct;59(8):657-673 |
1 | J:234630 Bonney S, Harrison-Uy S, Mishra S, MacPherson AM, Choe Y, Li D, Jaminet SC, Fruttiger M, Pleasure SJ, Siegenthaler JA, Diverse Functions of Retinoic Acid in Brain Vascular Development. J Neurosci. 2016 Jul 20;36(29):7786-801 |
1 | J:349721 Borisova E, Newman AG, Couce Iglesias M, Dannenberg R, Schaub T, Qin B, Rusanova A, Brockmann M, Koch J, Daniels M, Turko P, Jahn O, Kaplan DR, Rosario M, Iwawaki T, Spahn CMT, Rosenmund C, Meierhofer D, Kraushar ML, Tarabykin V, Ambrozkiewicz MC, Protein translation rate determines neocortical neuron fate. Nat Commun. 2024 Jun 7;15(1):4879 |
1 | J:324533 Calderon L, Weiss FD, Beagan JA, Oliveira MS, Georgieva R, Wang YF, Carroll TS, Dharmalingam G, Gong W, Tossell K, de Paola V, Whilding C, Ungless MA, Fisher AG, Phillips-Cremins JE, Merkenschlager M, Cohesin-dependence of neuronal gene expression relates to chromatin loop length. Elife. 2022 Apr 26;11:e76539 |
1 | J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5 |
1 | J:300487 Chai G, Webb A, Li C, Antaki D, Lee S, Breuss MW, Lang N, Stanley V, Anzenberg P, Yang X, Marshall T, Gaffney P, Wierenga KJ, Chung BH, Tsang MH, Pais LS, Lovgren AK, VanNoy GE, Rehm HL, Mirzaa G, Leon E, Diaz J, Neumann A, Kalverda AP, Manfield IW, Parry DA, Logan CV, Johnson CA, Bonthron DT, Valleley EMA, Issa MY, Abdel-Ghafar SF, Abdel-Hamid MS, Jennings P, Zaki MS, Sheridan E, Gleeson JG, Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 Jan 20;109(2):241-256.e9 |
1 | J:235552 Chinn GA, Hirokawa KE, Chuang TM, Urbina C, Patel F, Fong J, Funatsu N, Monuki ES, Agenesis of the Corpus Callosum Due to Defective Glial Wedge Formation in Lhx2 Mutant Mice. Cereb Cortex. 2015 Sep;25(9):2707-18 |
1 | J:229227 Colasante G, Simonet JC, Calogero R, Crispi S, Sessa A, Cho G, Golden JA, Broccoli V, ARX regulates cortical intermediate progenitor cell expansion and upper layer neuron formation through repression of Cdkn1c. Cereb Cortex. 2015 Feb;25(2):322-35 |
1 | J:192580 Diaz-Alonso J, Aguado T, Wu CS, Palazuelos J, Hofmann C, Garcez P, Guillemot F, Lu HC, Lutz B, Guzman M, Galve-Roperh I, The CB(1) cannabinoid receptor drives corticospinal motor neuron differentiation through the Ctip2/Satb2 transcriptional regulation axis. J Neurosci. 2012 Nov 21;32(47):16651-65 |
1 | J:174520 Enomoto T, Ohmoto M, Iwata T, Uno A, Saitou M, Yamaguchi T, Kominami R, Matsumoto I, Hirota J, Bcl11b/Ctip2 Controls the Differentiation of Vomeronasal Sensory Neurons in Mice. J Neurosci. 2011 Jul 13;31(28):10159-10173 |
1* | J:205524 Fujimori A, Itoh K, Goto S, Hirakawa H, Wang B, Kokubo T, Kito S, Tsukamoto S, Fushiki S, Disruption of Aspm causes microcephaly with abnormal neuronal differentiation. Brain Dev. 2014 Sep;36(8):661-9 |
1 | J:360819 Gabriel GC, Yagi H, Tan T, Bais A, Glennon BJ, Stapleton MC, Huang L, Reynolds WT, Shaffer MG, Ganapathiraju M, Simon D, Panigrahy A, Wu YL, Lo CW, Mitotic block and epigenetic repression underlie neurodevelopmental defects and neurobehavioral deficits in congenital heart disease. Nat Commun. 2025 Jan 7;16(1):469 |
1* | J:123724 Golonzhka O, Leid M, Indra G, Indra AK, Expression of COUP-TF-interacting protein 2 (CTIP2) in mouse skin during development and in adulthood. Gene Expr Patterns. 2007 Aug;7(7):754-60 |
1* | J:146765 Golonzhka O, Metzger D, Bornert JM, Bay BK, Gross MK, Kioussi C, Leid M, Ctip2/Bcl11b controls ameloblast formation during mammalian odontogenesis. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4278-83 |
2 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:230652 Harb K, Magrinelli E, Nicolas CS, Lukianets N, Frangeul L, Pietri M, Sun T, Sandoz G, Grammont F, Jabaudon D, Studer M, Alfano C, Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications. Elife. 2016;5:e09531 |
2* | J:332929 Harnett D, Ambrozkiewicz MC, Zinnall U, Rusanova A, Borisova E, Drescher AN, Couce-Iglesias M, Villamil G, Dannenberg R, Imami K, Munster-Wandowski A, Fauler B, Mielke T, Selbach M, Landthaler M, Spahn CMT, Tarabykin V, Ohler U, Kraushar ML, A critical period of translational control during brain development at codon resolution. Nat Struct Mol Biol. 2022 Dec;29(12):1277-1290 |
1* | J:220612 Holmes G, van Bakel H, Zhou X, Losic B, Jabs EW, BCL11B expression in intramembranous osteogenesis during murine craniofacial suture development. Gene Expr Patterns. 2015 Jan;17(1):16-25 |
1 | J:338359 Kaur N, Han W, Li Z, Madrigal MP, Shim S, Pochareddy S, Gulden FO, Li M, Xu X, Xing X, Takeo Y, Li Z, Lu K, Imamura Kawasawa Y, Ballester-Lurbe B, Moreno-Bravo JA, Chedotal A, Terrado J, Perez-Roger I, Koleske AJ, Sestan N, Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold. Neuron. 2020 Sep 23;107(6):1197-1211.e9 |
1 | J:222255 Knock E, Pereira J, Lombard PD, Dimond A, Leaford D, Livesey FJ, Hendrich B, The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex. Neural Dev. 2015;10:13 |
1 | J:315293 Kumamoto T, Toma K, Gunadi, McKenna WL, Kasukawa T, Katzman S, Chen B, Hanashima C, Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013 Mar 28;3(3):931-45 |
1 | J:343097 Kurabayashi N, Fujii K, Otobe Y, Hiroki S, Hiratsuka M, Yoshitane H, Kazuki Y, Takao K, Neocortical neuronal production and maturation defects in the TcMAC21 mouse model of Down syndrome. iScience. 2023 Dec 15;26(12):108379 |
1 | J:233640 Kyrylkova K, Iwaniec UT, Philbrick KA, Leid M, BCL11B regulates sutural patency in the mouse craniofacial skeleton. Dev Biol. 2016 Jul 15;415(2):251-60 |
2 | J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670 |
1 | J:332919 Leca I, Phillips AW, Ushakova L, Cushion TD, Keays DA, Codon modification of Tuba1a alters mRNA levels and causes a severe neurodevelopmental phenotype in mice. Sci Rep. 2023 Jan 21;13(1):1215 |
1 | J:235635 Leone DP, Heavner WE, Ferenczi EA, Dobreva G, Huguenard JR, Grosschedl R, McConnell SK, Satb2 Regulates the Differentiation of Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex. Cereb Cortex. 2015 Oct;25(10):3406-19 |
1 | J:297798 Li L, Ghorbani M, Weisz-Hubshman M, Rousseau J, Thiffault I, Schnur RE, Breen C, Oegema R, Weiss MM, Waisfisz Q, Welner S, Kingston H, Hills JA, Boon EM, Basel-Salmon L, Konen O, Goldberg-Stern H, Bazak L, Tzur S, Jin J, Bi X, Bruccoleri M, McWalter K, Cho MT, Scarano M, Schaefer GB, Brooks SS, Hughes SS, van Gassen KLI, van Hagen JM, Pandita TK, Agrawal PB, Campeau PM, Yang XJ, Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability. J Clin Invest. 2020 Mar 2;130(3):1431-1445 |
1 | J:306873 Li L, Jin J, Yang XJ, Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells. iScience. 2019 Oct 25;20:148-167 |
1 | J:361228 Li Z, Shang Z, Sun M, Jiang X, Tian Y, Yang L, Wang Z, Su Z, Liu G, Li X, You Y, Yang Z, Xu Z, Zhang Z, Transcription factor Sp9 is a negative regulator of D1-type MSN development. Cell Death Discov. 2022 Jun 30;8(1):301 |
1 | J:348287 Liang XG, Hoang K, Meyerink BL, Kc P, Paraiso K, Wang L, Jones IR, Zhang Y, Katzman S, Finn TS, Tsyporin J, Qu F, Chen Z, Visel A, Kriegstein A, Shen Y, Pilaz LJ, Chen B, A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex. Proc Natl Acad Sci U S A. 2024 May 14;121(20):e2321711121 |
1 | J:292113 Lin YN, Lee YS, Li SK, Tang TK, Loss of CPAP in developing mouse brain and its functional implication for human primary microcephaly. J Cell Sci. 2020 Jun 24;133(12):jcs243592 |
2 | J:325428 Liu J, Yang M, Su M, Liu B, Zhou K, Sun C, Ba R, Yu B, Zhang B, Zhang Z, Fan W, Wang K, Zhong M, Han J, Zhao C, FOXG1 sequentially orchestrates subtype specification of postmitotic cortical projection neurons. Sci Adv. 2022 May 27;8(21):eabh3568 |
1 | J:334752 Liu W, Xie H, Liu X, Xu S, Cheng S, Wang Z, Xie T, Zhang ZC, Han J, PQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation. Cell Rep. 2023 Mar 28;42(3):112277 |
1 | J:267913 Liu WA, Chen S, Li Z, Lee CH, Mirzaa G, Dobyns WB, Ross ME, Zhang J, Shi SH, PARD3 dysfunction in conjunction with dynamic HIPPO signaling drives cortical enlargement with massive heterotopia. Genes Dev. 2018 Jun 1;32(11-12):763-780 |
1 | J:197034 Lopez-Sanchez N, Frade JM, Genetic evidence for p75NTR-dependent tetraploidy in cortical projection neurons from adult mice. J Neurosci. 2013 Apr 24;33(17):7488-500 |
1* | J:346057 Lu D, Zhi Y, Su H, Lin X, Lin J, Shi Y, Yi W, Hong C, Zhang T, Fu Z, Chen LY, Zhao Z, Li R, Xu Z, Chen W, Wang N, Xu D, ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells. Cell Rep. 2024 Feb 24;43(3):113818 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:241849 Ma S, Santhosh D, Kumar T P, Huang Z, A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis. Dev Cell. 2017 May 22;41(4):366-381.e4 |
1 | J:338454 Marfull-Oromi P, Fleitas C, Zammou B, Rocandio D, Ballester-Lurbe B, Terrado J, Perez-Roger I, Espinet C, Egea J, Genetic ablation of the Rho GTPase Rnd3 triggers developmental defects in internal capsule and the globus pallidus formation. J Neurochem. 2021 Jul;158(2):197-216 |
1 | J:322988 Markert F, Storch A, Hyperoxygenation During Mid-Neurogenesis Accelerates Cortical Development in the Fetal Mouse Brain. Front Cell Dev Biol. 2022;10:732682 |
1 | J:341276 Matrongolo MJ, Ho-Nguyen KT, Jain M, Ang PS, Reddy A, Schaper S, Tischfield MA, Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice. Development. 2023 Sep 15;150(18):dev201381 |
1 | J:306233 Mesman S, Bakker R, Smidt MP, Tcf4 is required for correct brain development during embryogenesis. Mol Cell Neurosci. 2020 Jul;106:103502 |
1 | J:238369 Mihalas AB, Elsen GE, Bedogni F, Daza RA, Ramos-Laguna KA, Arnold SJ, Hevner RF, Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity. Cell Rep. 2016 Jun 28;16(1):92-105 |
1 | J:310398 Mire E, Hocine M, Bazellieres E, Jungas T, Davy A, Chauvet S, Mann F, Developmental Upregulation of Ephrin-B1 Silences Sema3C/Neuropilin-1 Signaling during Post-crossing Navigation of Corpus Callosum Axons. Curr Biol. 2018 Jun 4;28(11):1768-1782.e4 |
1 | J:101030 Molyneaux BJ, Arlotta P, Hirata T, Hibi M, Macklis JD, Fezl is required for the birth and specification of corticospinal motor neurons. Neuron. 2005 Sep 15;47(6):817-31 |
1* | J:219340 Molyneaux BJ, Goff LA, Brettler AC, Chen HH, Brown JR, Hrvatin S, Rinn JL, Arlotta P, DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex. Neuron. 2015 Jan 21;85(2):275-88 |
1 | J:331478 Monko T, Rebertus J, Stolley J, Salton SR, Nakagawa Y, Thalamocortical axons regulate neurogenesis and laminar fates in the early sensory cortex. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2201355119 |
1 | J:226687 Morello F, Prasad AA, Rehberg K, Vieira de Sa R, Anton-Bolanos N, Leyva-Diaz E, Adolfs Y, Tissir F, Lopez-Bendito G, Pasterkamp RJ, Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development. J Neurosci. 2015 Oct 21;35(42):14205-19 |
1 | J:335191 Munz M, Bharioke A, Kosche G, Moreno-Juan V, Brignall A, Rodrigues TM, Graff-Meyer A, Ulmer T, Haeuselmann S, Pavlinic D, Ledergerber N, Gross-Scherf B, Rozsa B, Krol J, Picelli S, Cowan CS, Roska B, Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex. Cell. 2023 Apr 27;186(9):1930-1949.e31 |
1 | J:250180 Nakagawa N, Yagi H, Kato K, Takematsu H, Oka S, Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy. Sci Rep. 2015 Jun 10;5:11163 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1* | J:234993 Nishiguchi Y, Ohmoto M, Koki J, Enomoto T, Kominami R, Matsumoto I, Hirota J, Bcl11b/Ctip2 is required for development of lingual papillae in mice. Dev Biol. 2016 Aug 1;416(1):98-110 |
1 | J:207850 Nishizaki Y, Takagi T, Matsui F, Higashi Y, SIP1 expression patterns in brain investigated by generating a SIP1-EGFP reporter knock-in mouse. Genesis. 2014 Jan;52(1):56-67 |
1 | J:240398 Ogino H, Hisanaga A, Kohno T, Kondo Y, Okumura K, Kamei T, Sato T, Asahara H, Tsuiji H, Fukata M, Hattori M, Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin. J Neurosci. 2017 Mar 22;37(12):3181-3191 |
1 | J:330578 Qian X, DeGennaro EM, Talukdar M, Akula SK, Lai A, Shao DD, Gonzalez D, Marciano JH, Smith RS, Hylton NK, Yang E, Bazan JF, Barrett L, Yeh RC, Hill RS, Beck SG, Otani A, Angad J, Mitani T, Posey JE, Pehlivan D, Calame D, Aydin H, Yesilbas O, Parks KC, Argilli E, England E, Im K, Taranath A, Scott HS, Barnett CP, Arts P, Sherr EH, Lupski JR, Walsh CA, Loss of non-motor kinesin KIF26A causes congenital brain malformations via dysregulated neuronal migration and axonal growth as well as apoptosis. Dev Cell. 2022 Oct 24;57(20):2381-2396.e13 |
1 | J:182304 Ross SE, McCord AE, Jung C, Atan D, Mok SI, Hemberg M, Kim TK, Salogiannis J, Hu L, Cohen S, Lin Y, Harrar D, McInnes RR, Greenberg ME, Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly. Neuron. 2012 Jan 26;73(2):292-303 |
1 | J:269511 Roy A, Skibo J, Kalume F, Ni J, Rankin S, Lu Y, Dobyns WB, Mills GB, Zhao JJ, Baker SJ, Millen KJ, Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy. Elife. 2015 Dec 3;4:e12703 |
1 | J:341708 Saha S, Jungas TT, Ohayon D, Audouard C, Ye T, Fawal MA, Davy A, Dihydrofolate reductase activity controls neurogenic transitions in the developing neocortex. Development. 2023 Oct 15;150(20):dev201696 |
1* | J:291094 Sheikh BN, Guhathakurta S, Tsang TH, Schwabenland M, Renschler G, Herquel B, Bhardwaj V, Holz H, Stehle T, Bondareva O, Aizarani N, Mossad O, Kretz O, Reichardt W, Chatterjee A, Braun LJ, Thevenon J, Sartelet H, Blank T, Grun D, von Elverfeldt D, Huber TB, Vestweber D, Avilov S, Prinz M, Buescher JM, Akhtar A, Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nat Cell Biol. 2020 Jul;22(7):828-841 |
1 | J:157301 Siegenthaler JA, Ashique AM, Zarbalis K, Patterson KP, Hecht JH, Kane MA, Folias AE, Choe Y, May SR, Kume T, Napoli JL, Peterson AS, Pleasure SJ, Retinoic acid from the meninges regulates cortical neuron generation. Cell. 2009 Oct 30;139(3):597-609 |
1 | J:350099 Song X, Chen H, Shang Z, Du H, Li Z, Wen Y, Liu G, Qi D, You Y, Yang Z, Zhang Z, Xu Z, Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons. Neurosci Bull. 2021 Jul;37(7):985-998 |
1* | J:324710 Stanton-Turcotte D, Hsu K, Moore SA, Yamada M, Fawcett JP, Iulianella A, Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development. J Neurosci. 2022 May 11;42(19):3931-3948 |
1 | J:216104 Sugiyama T, Osumi N, Katsuyama Y, A novel cell migratory zone in the developing hippocampal formation. J Comp Neurol. 2014 Oct 15;522(15):3520-38 |
1 | J:320749 Sun YY, Chen WJ, Huang ZP, Yang G, Wu ML, Xu DE, Yang WL, Luo YC, Xiao ZC, Xu RX, Ma QH, TRIM32 Deficiency Impairs the Generation of Pyramidal Neurons in Developing Cerebral Cortex. Cells. 2022 Jan 28;11(3) |
2 | J:309656 Sunohara T, Morizane A, Matsuura S, Miyamoto S, Saito H, Takahashi J, MicroRNA-Based Separation of Cortico-Fugal Projection Neuron-Like Cells Derived From Embryonic Stem Cells. Front Neurosci. 2019;13:1141 |
2 | J:188109 Tan SL, Nishi M, Ohtsuka T, Matsui T, Takemoto K, Kamio-Miura A, Aburatani H, Shinkai Y, Kageyama R, Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development. Development. 2012 Oct;139(20):3806-16 |
1 | J:278287 Tang T, Zhang Y, Wang Y, Cai Z, Lu Z, Li L, Huang R, Hagelkruys A, Matthias P, Zhang H, Seiser C, Xie Y, HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development. Neuron. 2019 Mar 20;101(6):1117-1133.e5 |
1 | J:333324 Tominaga K, Sakashita E, Kasashima K, Kuroiwa K, Nagao Y, Iwamori N, Endo H, Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells. Int J Mol Sci. 2023 Jan 20;24(3) |
1 | J:343099 Tonosaki M, Fujimori A, Yaoi T, Itoh K, Loss of Aspm causes increased apoptosis of developing neural cells during mouse cerebral corticogenesis. PLoS One. 2023;18(11):e0294893 |
1 | J:304564 Venkataramanappa S, Schutz D, Saaber F, Kumar PA, Abe P, Schulz S, Stumm R, The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS Genet. 2021 Mar;17(3):e1009441 |
1 | J:309451 Vinsland E, Baskaran P, Mihaylov SR, Hobbs C, Wood H, Bouybayoune I, Shah K, Houart C, Tee AR, Murn J, Fernandes C, Bateman JM, The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021 Aug 11;11(1):16299 |
1* | J:316179 Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y, An epigenetic circuit controls neurogenic programs during neocortex development. Development. 2021;148:dev199772 |
1 | J:235720 Wang PS, Chou FS, Ramachandran S, Xia S, Chen HY, Guo F, Suraneni P, Maher BJ, Li R, Crucial roles of the Arp2/3 complex during mammalian corticogenesis. Development. 2016 Aug 1;143(15):2741-52 |
1 | J:236342 Wang W, Jossin Y, Chai G, Lien WH, Tissir F, Goffinet AM, Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun. 2016 Mar 04;7:10936 |
1* | J:281257 Witteveen JS, Willemsen MH, Dombroski TC, van Bakel NH, Nillesen WM, van Hulten JA, Jansen EJ, Verkaik D, Veenstra-Knol HE, van Ravenswaaij-Arts CM, Wassink-Ruiter JS, Vincent M, David A, Le Caignec C, Schieving J, Gilissen C, Foulds N, Rump P, Strom T, Cremer K, Zink AM, Engels H, de Munnik SA, Visser JE, Brunner HG, Martens GJ, Pfundt R, Kleefstra T, Kolk SM, Haploinsufficiency of MeCP2-interacting transcriptional co-repressor SIN3A causes mild intellectual disability by affecting the development of cortical integrity. Nat Genet. 2016 Aug;48(8):877-87 |
1 | J:267715 Wiwatpanit T, Lorenzen SM, Cantu JA, Foo CZ, Hogan AK, Marquez F, Clancy JC, Schipma MJ, Cheatham MA, Duggan A, Garcia-Anoveros J, Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1. Nature. 2018 Nov;563(7733):691-695 |
1 | J:235394 Woodworth MB, Greig LC, Liu KX, Ippolito GC, Tucker HO, Macklis JD, Ctip1 Regulates the Balance between Specification of Distinct Projection Neuron Subtypes in Deep Cortical Layers. Cell Rep. 2016 May 3;15(5):999-1012 |
1 | J:177905 Yamasaki T, Kawasaki H, Arakawa S, Shimizu K, Shimizu S, Reiner O, Okano H, Nishina S, Azuma N, Penninger JM, Katada T, Nishina H, Stress-Activated Protein Kinase MKK7 Regulates Axon Elongation in the Developing Cerebral Cortex. J Neurosci. 2011 Nov 16;31(46):16872-16883 |
1 | J:299730 Zhang L, Jing H, Li H, Chen W, Luo B, Zhang H, Dong Z, Li L, Su H, Xiong WC, Mei L, Neddylation is critical to cortical development by regulating Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26448-26459 |
2 | J:225082 Zhang LJ, Bhattacharya S, Leid M, Ganguli-Indra G, Indra AK, Ctip2 is a dynamic regulator of epidermal proliferation and differentiation by integrating EGFR and Notch signaling. J Cell Sci. 2012 Dec 1;125(Pt 23):5733-44 |
1 | J:328995 Zhang SF, Dai SK, Du HZ, Wang H, Li XG, Tang Y, Liu CM, The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis. Stem Cell Reports. 2022 Sep 13;17(9):2064-2080 |
1 | J:287752 Zhang W, Ma L, Yang M, Shao Q, Xu J, Lu Z, Zhao Z, Chen R, Chai Y, Chen JF, Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes. Genes Dev. 2020 Apr 1;34(7-8):580-597 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
1 | J:324298 Zhou J, Liu G, Zhang X, Wu C, Ma M, Wu J, Hou L, Yin B, Qiang B, Shu P, Peng X, Comparison of the Spatiotemporal Expression Patterns of Three Cre Lines, Emx1IRES-Cre, D6-Cre and hGFAP-Cre, Commonly Used in Neocortical Development Research. Cereb Cortex. 2022 Apr 5;32(8):1668-1681 |
1 | J:160192 Zhou W, Zhang Y, Li Y, Wei YS, Liu G, Liu DP, Pleasure SJ, Xie W, Zhao C, A transgenic Cre mouse line for the study of cortical and hippocampal development. Genesis. 2010 May;48(5):343-50 |
1 | J:343098 Zhou Z, Pan Y, Zhou S, Wang S, Zhang D, Cao Y, Jiang X, Li J, Zhu L, Zhao L, Gu S, Lin G, Dong Z, Sun HX, Single-cell analysis reveals specific neuronal transition during mouse corticogenesis. Front Cell Dev Biol. 2023;11:1209320 |
Bclaf1 BCL2-associated transcription factor 1 (Synonyms: 2610102K23Rik, 2700025J07Rik, 2810454G14Rik, 5730534O06Rik, mKIAA0164) | |
Results | Reference |
1 | J:158087 McPherson JP, Sarras H, Lemmers B, Tamblyn L, Migon E, Matysiak-Zablocki E, Hakem A, Azami SA, Cardoso R, Fish J, Sanchez O, Post M, Hakem R, Essential role for Bclaf1 in lung development and immune system function. Cell Death Differ. 2009 Feb;16(2):331-9 |
1 | J:206963 Orieux G, Picault L, Slembrouck A, Roger JE, Guillonneau X, Sahel JA, Saule S, McPherson JP, Goureau O, Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells. J Neurosci. 2014 Jan 22;34(4):1530-41 |
Bcor BCL6 interacting corepressor (Synonyms: 2900008C10Rik, 5830466J11Rik, 8430401K06Rik, D930024N20Rik, mKIAA1575) | |
Results | Reference |
3 | J:329268 Langouet M, Jolicoeur C, Javed A, Mattar P, Gearhart MD, Daiger SP, Bertelsen M, Tranebjaerg L, Rendtorff ND, Gronskov K, Jespersgaard C, Chen R, Sun Z, Li H, Alirezaie N, Majewski J, Bardwell VJ, Sui R, Koenekoop RK, Cayouette M, Mutations in BCOR, a co-repressor of CRX/OTX2, are associated with early-onset retinal degeneration. Sci Adv. 2022 Sep 9;8(36):eabh2868 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:120108 Wamstad JA, Bardwell VJ, Characterization of Bcor expression in mouse development. Gene Expr Patterns. 2007 Apr;7(5):550-7 |
Bdkrb2 bradykinin receptor, beta 2 (Synonyms: B(2), B2, B2R, BK2R, kinin B2) | |
Results | Reference |
1 | J:183431 Aboudehen K, Hilliard S, Saifudeen Z, El-Dahr SS, Mechanisms of p53 activation and physiological relevance in the developing kidney. Am J Physiol Renal Physiol. 2012 Apr;302(8):F928-40 |
Bdnf brain derived neurotrophic factor | |
Results | Reference |
1 | J:181188 Aoki H, Hara A, Era T, Kunisada T, Yamada Y, Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development. 2012 Feb;139(4):667-77 |
1 | J:98945 Ballas N, Grunseich C, Lu DD, Speh JC, Mandel G, REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell. 2005 May 20;121(4):645-57 |
1 | J:194255 Baydyuk M, Xie Y, Tessarollo L, Xu B, Midbrain-derived neurotrophins support survival of immature striatal projection neurons. J Neurosci. 2013 Feb 20;33(8):3363-9 |
1 | J:65040 Botchkareva NV, Botchkarev VA, Albers KM, Metz M, Paus R, Distinct roles for nerve growth factor and brain-derived neurotrophic factor in controlling the rate of hair follicle morphogenesis. J Invest Dermatol. 2000 Feb;114(2):314-20 |
1* | J:157986 Childs AJ, Bayne RA, Murray AA, Martins Da Silva SJ, Collins CS, Spears N, Anderson RA, Differential expression and regulation by activin of the neurotrophins BDNF and NT4 during human and mouse ovarian development. Dev Dyn. 2010 Feb 19;239(4):1211-1219 |
1* | J:93143 Clough RL, Sud R, Davis-Silberman N, Hertzano R, Avraham KB, Holley M, Dawson SJ, Brn-3c (POU4F3) regulates BDNF and NT-3 promoter activity. Biochem Biophys Res Commun. 2004 Nov 5;324(1):372-81 |
1 | J:102722 Dennis KE, Levitt P, Regional expression of brain derived neurotrophic factor (BDNF) is correlated with dynamic patterns of promoter methylation in the developing mouse forebrain. Brain Res Mol Brain Res. 2005 Oct 31;140(1-2):1-9 |
1 | J:276557 Hong GS, Lee SH, Lee B, Choi JH, Oh SJ, Jang Y, Hwang EM, Kim H, Jung J, Kim IB, Oh U, ANO1/TMEM16A regulates process maturation in radial glial cells in the developing brain. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12494-12499 |
2 | J:165547 Huang T, Krimm RF, Developmental expression of Bdnf, Ntf4/5, and TrkB in the mouse peripheral taste system. Dev Dyn. 2010 Oct;239(10):2637-46 |
1 | J:37118 McEvilly RJ, Erkman L, Luo L, Sawchenko PE, Ryan AF, Rosenfeld MG, Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature. 1996 Dec 12;384(6609):574-7 |
1 | J:176574 Peng C, Aron L, Klein R, Li M, Wurst W, Prakash N, Le W, Pitx3 Is a Critical Mediator of GDNF-Induced BDNF Expression in Nigrostriatal Dopaminergic Neurons. J Neurosci. 2011 Sep 7;31(36):12802-12815 |
1* | J:85731 Spears N, Molinek MD, Robinson LL, Fulton N, Cameron H, Shimoda K, Telfer EE, Anderson RA, Price DJ, The role of neurotrophin receptors in female germ-cell survival in mouse and human. Development. 2003 Nov;130(22):5481-91 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Becn1 beclin 1, autophagy related (Synonyms: Atg6, MGC:6843) | |
Results | Reference |
1 | J:233601 Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP, Harwood CA, Byrne C, O'Shaughnessy RF, Bergamaschi D, Constitutive Autophagy and Nucleophagy during Epidermal Differentiation. J Invest Dermatol. 2016 Jul;136(7):1460-70 |
1 | J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410 |
1 | J:361606 Wei W, Gao X, Qian J, Li L, Zhao C, Xu L, Zhu Y, Liu Z, Liu N, Wang X, Jin Z, Liu B, Xu L, Dong J, Zhang S, Wang J, Zhang Y, Yu Y, Yan Z, Yang Y, Lu J, Fang Y, Yuan N, Wang J, Beclin 1 prevents ISG15-mediated cytokine storms to secure fetal hematopoiesis and survival. J Clin Invest. 2025 Feb 3;135(3) |
2* | J:318994 Yang J, Wan C, Nie S, Jian S, Sun Z, Zhang L, Chen Z, Localization of Beclin1 in mouse developing tooth germs: possible implication of the interrelation between autophagy and apoptosis. J Mol Histol. 2013 Dec;44(6):619-27 |
1 | J:280538 Yeganeh B, Lee J, Ermini L, Lok I, Ackerley C, Post M, Autophagy is required for lung development and morphogenesis. J Clin Invest. 2019 Jun 4;129(7):2904-2919 |
Bex2 brain expressed X-linked 2 (Synonyms: Bex1) | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Bglap bone gamma carboxyglutamate protein (Synonyms: Bglap1, bone Gla protein, mOC-A, OC, OG1, osteocalcin) | |
Results | Reference |
1 | J:90567 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 2004 May 1;18(9):1072-87 |
1 | J:47096 Bidder M, Latifi T, Towler DA, Reciprocal temporospatial patterns of Msx2 and Osteocalcin gene expression during murine odontogenesis. J Bone Miner Res. 1998 Apr;13(4):609-19 |
1 | J:181527 Chaible LM, Sanches DS, Cogliati B, Mennecier G, Dagli ML, Delayed osteoblastic differentiation and bone development in Cx43 knockout mice. Toxicol Pathol. 2011 Dec;39(7):1046-55 |
1 | J:185530 Chan KM, Wong HL, Jin G, Liu B, Cao R, Cao Y, Lehti K, Tryggvason K, Zhou Z, MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis. Dev Cell. 2012 Jun 12;22(6):1176-90 |
1 | J:208766 Chen J, Tu X, Esen E, Joeng KS, Lin C, Arbeit JM, Ruegg MA, Hall MN, Ma L, Long F, WNT7B promotes bone formation in part through mTORC1. PLoS Genet. 2014 Jan;10(1):e1004145 |
1* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:293199 Crespo-Enriquez I, Hodgson T, Zakaria S, Cadoni E, Shah M, Allen S, Al-Khishali A, Mao Y, Yiu A, Petzold J, Villagomez-Olea G, Pitsillides AA, Irvine KD, Francis-West P, Dchs1-Fat4 regulation of osteogenic differentiation in mouse. Development. 2019 Jul 29;146(14):dev176776 |
2* | J:16427 Desbois C, Hogue DA, Karsenty G, The mouse osteocalcin gene cluster contains three genes with two separate spatial and temporal patterns of expression. J Biol Chem. 1994 Jan 14;269(2):1183-90 |
1* | J:195901 Ehlen H, Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues. J Bone Miner Res. 2013;28(2):246-59 |
1 | J:127545 Engleka KA, Wu M, Zhang M, Antonucci NB, Epstein JA, Menin is required in cranial neural crest for palatogenesis and perinatal viability. Dev Biol. 2007 Nov 15;311(2):524-37 |
1* | J:111429 Feng JQ, Zhang J, Dallas SL, Lu Y, Chen S, Tan X, Owen M, Harris SE, MacDougall M, Dentin matrix protein 1, a target molecule for Cbfa1 in bone, is a unique bone marker gene. J Bone Miner Res. 2002 Oct;17(10):1822-31 |
1 | J:217210 Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H, Loss of Tbx1 induces bone phenotypes similar to cleidocranial dysplasia. Hum Mol Genet. 2015 Jan 15;24(2):424-35 |
1 | J:74145 Gori F, Schipani E, Demay MB, Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development. J Cell Biochem. 2001 Apr 2-27;82(1):46-57 |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1 | J:98426 Hill TP, Spater D, Taketo MM, Birchmeier W, Hartmann C, Canonical Wnt/beta-Catenin Signaling Prevents Osteoblasts from Differentiating into Chondrocytes. Dev Cell. 2005 May;8(5):727-38 |
1 | J:114686 Hinoi E, Bialek P, Chen YT, Rached MT, Groner Y, Behringer RR, Ornitz DM, Karsenty G, Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes Dev. 2006 Nov 1;20(21):2937-42 |
1 | J:176483 Holmes G, Bromage TG, Basilico C, The Sox2 high mobility group transcription factor inhibits mature osteoblast function in transgenic mice. Bone. 2011 Oct;49(4):653-61 |
1 | J:255577 Hsu WH, Chen CM, You LR, COUP-TFII is required for morphogenesis of the neural crest-derived tympanic ring. Sci Rep. 2017 Sep 28;7(1):12386 |
1 | J:122952 Hung IH, Yu K, Lavine KJ, Ornitz DM, FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. Dev Biol. 2007 Jul 15;307(2):300-13 |
1* | J:292270 Ideno H, Nakashima K, Komatsu K, Araki R, Abe M, Arai Y, Kimura H, Shinkai Y, Tachibana M, Nifuji A, G9a is involved in the regulation of cranial bone formation through activation of Runx2 function during development. Bone. 2020 Aug;137:115332 |
1 | J:153633 Ito T, Yadav N, Lee J, Furumatsu T, Yamashita S, Yoshida K, Taniguchi N, Hashimoto M, Tsuchiya M, Ozaki T, Lotz M, Bedford MT, Asahara H, Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC Dev Biol. 2009;9:47 |
1 | J:119288 Jacob AL, Smith C, Partanen J, Ornitz DM, Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation. Dev Biol. 2006 Aug 15;296(2):315-28 |
1 | J:94393 Karreth F, Hoebertz A, Scheuch H, Eferl R, Wagner EF, The AP1 transcription factor Fra2 is required for efficient cartilage development. Development. 2004 Nov;131(22):5717-25 |
1 | J:92212 Koziel L, Kunath M, Kelly OG, Vortkamp A, Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification. Dev Cell. 2004 Jun;6(6):801-13 |
1 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
1 | J:182649 Levi B, James AW, Nelson ER, Brugmann SA, Sorkin M, Manu A, Longaker MT, Role of Indian hedgehog signaling in palatal osteogenesis. Plast Reconstr Surg. 2011 Mar;127(3):1182-90 |
1 | J:319475 Liao C, Lu M, Hong Y, Mao C, Chen J, Ren C, Lin M, Chen W, Osteogenic and angiogenic profiles of the palatal process of the maxilla and the palatal process of the palatine bone. J Anat. 2022 Feb;240(2):385-397 |
1 | J:152843 Luo J, Zhou W, Zhou X, Li D, Weng J, Yi Z, Cho SG, Li C, Yi T, Wu X, Li XY, de Crombrugghe B, Hook M, Liu M, Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development. 2009 Aug;136(16):2747-56 |
1* | J:74493 Maes C, Carmeliet P, Moermans K, Stockmans I, Smets N, Collen D, Bouillon R, Carmeliet G, Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF(164) and VEGF(188). Mech Dev. 2002 Feb;111(1-2):61-73 |
1 | J:153980 Matsushita T, Chan YY, Kawanami A, Balmes G, Landreth GE, Murakami S, Extracellular signal-regulated kinase 1 (ERK1) and ERK2 play essential roles in osteoblast differentiation and in supporting osteoclastogenesis. Mol Cell Biol. 2009 Nov;29(21):5843-57 |
1 | J:182340 Michikami I, Fukushi T, Tanaka M, Egusa H, Maeda Y, Ooshima T, Wakisaka S, Abe M, Kruppel-like factor 4 regulates membranous and endochondral ossification. Exp Cell Res. 2012 Feb 15;318(4):311-25 |
1 | J:149225 Miclea RL, Karperien M, Bosch CA, van der Horst G, van der Valk MA, Kobayashi T, Kronenberg HM, Rawadi G, Akcakaya P, Lowik CW, Fodde R, Wit JM, Robanus-Maandag EC, Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors. BMC Dev Biol. 2009;9:26 |
1* | J:153103 Mikura A, Okuhara S, Saito M, Ota M, Ueda K, Iseki S, Association of tenascin-W expression with mineralization in mouse calvarial development. Congenit Anom (Kyoto). 2009 Jun;49(2):77-84 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:165333 Nishikawa K, Nakashima T, Takeda S, Isogai M, Hamada M, Kimura A, Kodama T, Yamaguchi A, Owen MJ, Takahashi S, Takayanagi H, Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation. J Clin Invest. 2010 Oct 1;120(10):3455-65 |
1 | J:135374 Patra D, Xing X, Davies S, Bryan J, Franz C, Hunziker EB, Sandell LJ, Site-1 protease is essential for endochondral bone formation in mice. J Cell Biol. 2007 Nov 19;179(4):687-700 |
1 | J:76480 Robledo RF, Rajan L, Li X, Lufkin T, The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev. 2002 May 1;16(9):1089-101 |
1 | J:340421 Ruscitto A, Chen P, Tosa I, Wang Z, Zhou G, Safina I, Wei R, Morel MM, Koch A, Forman M, Reeve G, Lecholop MK, Wilson M, Bonthius D, Chen M, Ono M, Wang TC, Yao H, Embree MC, Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity. Cell Stem Cell. 2023 Sep 7;30(9):1179-1198.e7 |
1* | J:306243 Shur I, Socher R, Benayahu D, In vivo association of CReMM/CHD9 with promoters in osteogenic cells. J Cell Physiol. 2006 May;207(2):374-8 |
1 | J:95959 Smith N, Dong Y, Lian JB, Pratap J, Kingsley PD, van Wijnen AJ, Stein JL, Schwarz EM, O'keefe RJ, Stein GS, Drissi MH, Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. J Cell Physiol. 2005 Apr;203(1):133-43 |
1 | J:124088 Soung do Y, Dong Y, Wang Y, Zuscik MJ, Schwarz EM, O'Keefe RJ, Drissi H, Runx3/AML2/Cbfa3 regulates early and late chondrocyte differentiation. J Bone Miner Res. 2007 Aug;22(8):1260-70 |
1 | J:333326 Suh J, Kim NK, Shim W, Lee SH, Kim HJ, Moon E, Sesaki H, Jang JH, Kim JE, Lee YS, Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab. 2023 Feb 7;35(2):345-360.e7 |
1 | J:287435 Sun P, He L, Jia K, Yue Z, Li S, Jin Y, Li Z, Siwko S, Xue F, Su J, Liu M, Luo J, Regulation of body length and bone mass by Gpr126/Adgrg6. Sci Adv. 2020 Mar;6(12):eaaz0368 |
1 | J:125052 Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H, Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification. Mol Cell Biol. 2007 Aug;27(16):5650-63 |
1* | J:87170 Thomas G, Moffatt P, Salois P, Gaumond MH, Gingras R, Godin E, Miao D, Goltzman D, Lanctot C, Osteocrin, a novel bone-specific secreted protein that modulates the osteoblast phenotype. J Biol Chem. 2003 Dec 12;278(50):50563-71 |
1 | J:132462 Wang K, Yamamoto H, Chin JR, Werb Z, Vu TH, Epidermal growth factor receptor-deficient mice have delayed primary endochondral ossification because of defective osteoclast recruitment. J Biol Chem. 2004 Dec 17;279(51):53848-56 |
1 | J:185130 Wei J, Shi Y, Zheng L, Zhou B, Inose H, Wang J, Guo XE, Grosschedl R, Karsenty G, miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. J Cell Biol. 2012 May 14;197(4):509-21 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1 | J:138616 Yang X, Harkins LK, Zubanova O, Harrington A, Kovalenko D, Nadeau RJ, Chen PY, Toher JL, Lindner V, Liaw L, Friesel R, Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia. Dev Biol. 2008 Sep 1;321(1):64-76 |
1* | J:334015 Yoshioka H, Komura S, Kuramitsu N, Goto A, Hasegawa T, Amizuka N, Ishimoto T, Ozasa R, Nakano T, Imai Y, Akiyama H, Deletion of Tfam in Prx1-Cre expressing limb mesenchyme results in spontaneous bone fractures. J Bone Miner Metab. 2022 Sep;40(5):839-852 |
1* | J:90391 Yu K, Xu J, Liu Z, Sosic D, Shao J, Olson EN, Towler DA, Ornitz DM, Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development. 2003 Jul;130(13):3063-74 |
1* | J:75934 Zelzer E, McLean W, Ng YS, Fukai N, Reginato AM, Lovejoy S, D'Amore PA, Olsen BR, Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development. 2002 Apr;129(8):1893-904 |
Bglap2 bone gamma-carboxyglutamate protein 2 (Synonyms: bone Gla protein, mOC-B, OG2, osteocalcin) | |
Results | Reference |
1 | J:90567 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 2004 May 1;18(9):1072-87 |
1 | J:47096 Bidder M, Latifi T, Towler DA, Reciprocal temporospatial patterns of Msx2 and Osteocalcin gene expression during murine odontogenesis. J Bone Miner Res. 1998 Apr;13(4):609-19 |
1 | J:181527 Chaible LM, Sanches DS, Cogliati B, Mennecier G, Dagli ML, Delayed osteoblastic differentiation and bone development in Cx43 knockout mice. Toxicol Pathol. 2011 Dec;39(7):1046-55 |
1 | J:185530 Chan KM, Wong HL, Jin G, Liu B, Cao R, Cao Y, Lehti K, Tryggvason K, Zhou Z, MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis. Dev Cell. 2012 Jun 12;22(6):1176-90 |
1 | J:208766 Chen J, Tu X, Esen E, Joeng KS, Lin C, Arbeit JM, Ruegg MA, Hall MN, Ma L, Long F, WNT7B promotes bone formation in part through mTORC1. PLoS Genet. 2014 Jan;10(1):e1004145 |
1* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:293199 Crespo-Enriquez I, Hodgson T, Zakaria S, Cadoni E, Shah M, Allen S, Al-Khishali A, Mao Y, Yiu A, Petzold J, Villagomez-Olea G, Pitsillides AA, Irvine KD, Francis-West P, Dchs1-Fat4 regulation of osteogenic differentiation in mouse. Development. 2019 Jul 29;146(14):dev176776 |
2* | J:16427 Desbois C, Hogue DA, Karsenty G, The mouse osteocalcin gene cluster contains three genes with two separate spatial and temporal patterns of expression. J Biol Chem. 1994 Jan 14;269(2):1183-90 |
1* | J:195901 Ehlen H, Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues. J Bone Miner Res. 2013;28(2):246-59 |
1 | J:127545 Engleka KA, Wu M, Zhang M, Antonucci NB, Epstein JA, Menin is required in cranial neural crest for palatogenesis and perinatal viability. Dev Biol. 2007 Nov 15;311(2):524-37 |
1* | J:111429 Feng JQ, Zhang J, Dallas SL, Lu Y, Chen S, Tan X, Owen M, Harris SE, MacDougall M, Dentin matrix protein 1, a target molecule for Cbfa1 in bone, is a unique bone marker gene. J Bone Miner Res. 2002 Oct;17(10):1822-31 |
1 | J:217210 Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H, Loss of Tbx1 induces bone phenotypes similar to cleidocranial dysplasia. Hum Mol Genet. 2015 Jan 15;24(2):424-35 |
1 | J:74145 Gori F, Schipani E, Demay MB, Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development. J Cell Biochem. 2001 Apr 2-27;82(1):46-57 |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1 | J:98426 Hill TP, Spater D, Taketo MM, Birchmeier W, Hartmann C, Canonical Wnt/beta-Catenin Signaling Prevents Osteoblasts from Differentiating into Chondrocytes. Dev Cell. 2005 May;8(5):727-38 |
1 | J:114686 Hinoi E, Bialek P, Chen YT, Rached MT, Groner Y, Behringer RR, Ornitz DM, Karsenty G, Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes Dev. 2006 Nov 1;20(21):2937-42 |
1 | J:176483 Holmes G, Bromage TG, Basilico C, The Sox2 high mobility group transcription factor inhibits mature osteoblast function in transgenic mice. Bone. 2011 Oct;49(4):653-61 |
1 | J:255577 Hsu WH, Chen CM, You LR, COUP-TFII is required for morphogenesis of the neural crest-derived tympanic ring. Sci Rep. 2017 Sep 28;7(1):12386 |
1 | J:122952 Hung IH, Yu K, Lavine KJ, Ornitz DM, FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. Dev Biol. 2007 Jul 15;307(2):300-13 |
1* | J:292270 Ideno H, Nakashima K, Komatsu K, Araki R, Abe M, Arai Y, Kimura H, Shinkai Y, Tachibana M, Nifuji A, G9a is involved in the regulation of cranial bone formation through activation of Runx2 function during development. Bone. 2020 Aug;137:115332 |
1 | J:153633 Ito T, Yadav N, Lee J, Furumatsu T, Yamashita S, Yoshida K, Taniguchi N, Hashimoto M, Tsuchiya M, Ozaki T, Lotz M, Bedford MT, Asahara H, Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC Dev Biol. 2009;9:47 |
1 | J:119288 Jacob AL, Smith C, Partanen J, Ornitz DM, Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation. Dev Biol. 2006 Aug 15;296(2):315-28 |
1 | J:143588 Kamiya N, Ye L, Kobayashi T, Mochida Y, Yamauchi M, Kronenberg HM, Feng JQ, Mishina Y, BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development. 2008 Nov;135(22):3801-11 |
1 | J:94393 Karreth F, Hoebertz A, Scheuch H, Eferl R, Wagner EF, The AP1 transcription factor Fra2 is required for efficient cartilage development. Development. 2004 Nov;131(22):5717-25 |
1 | J:92212 Koziel L, Kunath M, Kelly OG, Vortkamp A, Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification. Dev Cell. 2004 Jun;6(6):801-13 |
1 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
1 | J:182649 Levi B, James AW, Nelson ER, Brugmann SA, Sorkin M, Manu A, Longaker MT, Role of Indian hedgehog signaling in palatal osteogenesis. Plast Reconstr Surg. 2011 Mar;127(3):1182-90 |
1 | J:319475 Liao C, Lu M, Hong Y, Mao C, Chen J, Ren C, Lin M, Chen W, Osteogenic and angiogenic profiles of the palatal process of the maxilla and the palatal process of the palatine bone. J Anat. 2022 Feb;240(2):385-397 |
1 | J:152843 Luo J, Zhou W, Zhou X, Li D, Weng J, Yi Z, Cho SG, Li C, Yi T, Wu X, Li XY, de Crombrugghe B, Hook M, Liu M, Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development. 2009 Aug;136(16):2747-56 |
1* | J:74493 Maes C, Carmeliet P, Moermans K, Stockmans I, Smets N, Collen D, Bouillon R, Carmeliet G, Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF(164) and VEGF(188). Mech Dev. 2002 Feb;111(1-2):61-73 |
1 | J:153980 Matsushita T, Chan YY, Kawanami A, Balmes G, Landreth GE, Murakami S, Extracellular signal-regulated kinase 1 (ERK1) and ERK2 play essential roles in osteoblast differentiation and in supporting osteoclastogenesis. Mol Cell Biol. 2009 Nov;29(21):5843-57 |
1 | J:296737 Matsuura VKSK, Yoshida CA, Komori H, Sakane C, Yamana K, Jiang Q, Komori T, Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice. Int J Mol Sci. 2020 Apr 12;21(8):2682 |
1 | J:182340 Michikami I, Fukushi T, Tanaka M, Egusa H, Maeda Y, Ooshima T, Wakisaka S, Abe M, Kruppel-like factor 4 regulates membranous and endochondral ossification. Exp Cell Res. 2012 Feb 15;318(4):311-25 |
1 | J:149225 Miclea RL, Karperien M, Bosch CA, van der Horst G, van der Valk MA, Kobayashi T, Kronenberg HM, Rawadi G, Akcakaya P, Lowik CW, Fodde R, Wit JM, Robanus-Maandag EC, Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors. BMC Dev Biol. 2009;9:26 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:165333 Nishikawa K, Nakashima T, Takeda S, Isogai M, Hamada M, Kimura A, Kodama T, Yamaguchi A, Owen MJ, Takahashi S, Takayanagi H, Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation. J Clin Invest. 2010 Oct 1;120(10):3455-65 |
1 | J:135374 Patra D, Xing X, Davies S, Bryan J, Franz C, Hunziker EB, Sandell LJ, Site-1 protease is essential for endochondral bone formation in mice. J Cell Biol. 2007 Nov 19;179(4):687-700 |
1 | J:76480 Robledo RF, Rajan L, Li X, Lufkin T, The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev. 2002 May 1;16(9):1089-101 |
1* | J:306243 Shur I, Socher R, Benayahu D, In vivo association of CReMM/CHD9 with promoters in osteogenic cells. J Cell Physiol. 2006 May;207(2):374-8 |
1 | J:95959 Smith N, Dong Y, Lian JB, Pratap J, Kingsley PD, van Wijnen AJ, Stein JL, Schwarz EM, O'keefe RJ, Stein GS, Drissi MH, Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. J Cell Physiol. 2005 Apr;203(1):133-43 |
1 | J:124088 Soung do Y, Dong Y, Wang Y, Zuscik MJ, Schwarz EM, O'Keefe RJ, Drissi H, Runx3/AML2/Cbfa3 regulates early and late chondrocyte differentiation. J Bone Miner Res. 2007 Aug;22(8):1260-70 |
1 | J:333326 Suh J, Kim NK, Shim W, Lee SH, Kim HJ, Moon E, Sesaki H, Jang JH, Kim JE, Lee YS, Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab. 2023 Feb 7;35(2):345-360.e7 |
1 | J:287435 Sun P, He L, Jia K, Yue Z, Li S, Jin Y, Li Z, Siwko S, Xue F, Su J, Liu M, Luo J, Regulation of body length and bone mass by Gpr126/Adgrg6. Sci Adv. 2020 Mar;6(12):eaaz0368 |
1 | J:125052 Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H, Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification. Mol Cell Biol. 2007 Aug;27(16):5650-63 |
1* | J:87170 Thomas G, Moffatt P, Salois P, Gaumond MH, Gingras R, Godin E, Miao D, Goltzman D, Lanctot C, Osteocrin, a novel bone-specific secreted protein that modulates the osteoblast phenotype. J Biol Chem. 2003 Dec 12;278(50):50563-71 |
1 | J:132462 Wang K, Yamamoto H, Chin JR, Werb Z, Vu TH, Epidermal growth factor receptor-deficient mice have delayed primary endochondral ossification because of defective osteoclast recruitment. J Biol Chem. 2004 Dec 17;279(51):53848-56 |
1 | J:185130 Wei J, Shi Y, Zheng L, Zhou B, Inose H, Wang J, Guo XE, Grosschedl R, Karsenty G, miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. J Cell Biol. 2012 May 14;197(4):509-21 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1 | J:138616 Yang X, Harkins LK, Zubanova O, Harrington A, Kovalenko D, Nadeau RJ, Chen PY, Toher JL, Lindner V, Liaw L, Friesel R, Overexpression of Spry1 in chondrocytes causes attenuated FGFR ubiquitination and sustained ERK activation resulting in chondrodysplasia. Dev Biol. 2008 Sep 1;321(1):64-76 |
1* | J:334015 Yoshioka H, Komura S, Kuramitsu N, Goto A, Hasegawa T, Amizuka N, Ishimoto T, Ozasa R, Nakano T, Imai Y, Akiyama H, Deletion of Tfam in Prx1-Cre expressing limb mesenchyme results in spontaneous bone fractures. J Bone Miner Metab. 2022 Sep;40(5):839-852 |
1* | J:90391 Yu K, Xu J, Liu Z, Sosic D, Shao J, Olson EN, Towler DA, Ornitz DM, Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development. 2003 Jul;130(13):3063-74 |
1* | J:75934 Zelzer E, McLean W, Ng YS, Fukai N, Reginato AM, Lovejoy S, D'Amore PA, Olsen BR, Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development. 2002 Apr;129(8):1893-904 |
Bglap3 bone gamma-carboxyglutamate protein 3 (Synonyms: Bglap-rs1, mOC-X, ORG) | |
Results | Reference |
1* | J:16427 Desbois C, Hogue DA, Karsenty G, The mouse osteocalcin gene cluster contains three genes with two separate spatial and temporal patterns of expression. J Biol Chem. 1994 Jan 14;269(2):1183-90 |
Bgn biglycan (Synonyms: BG, SLRR1A) | |
Results | Reference |
1* | J:320343 Randilini A, Fujikawa K, Shibata S, An in situ hybridization study of decorin and biglycan mRNA in mouse osteoblasts in vivo. Anat Sci Int. 2021 Mar;96(2):265-272 |
Bhlha15 basic helix-loop-helix family, member a15 (Synonyms: 1810009C13Rik, Bhlhb8, Mist1) | |
Results | Reference |
1 | J:341713 Aure MH, Symonds JM, Villapudua CU, Dodge JT, Werner S, Knosp WM, Hoffman MP, FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation. Nat Commun. 2023 Oct 14;14(1):6485 |
1 | J:104222 Fazio EN, Everest M, Colman R, Wang R, Pin CL, Altered Glut-2 accumulation and beta-cell function in mice lacking the exocrine-specific transcription factor, Mist1. J Endocrinol. 2005 Dec;187(3):407-18 |
1 | J:192856 George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE, Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol. 2012 Dec;32(24):5116-28 |
1* | J:90459 Johnson CL, Kowalik AS, Rajakumar N, Pin CL, Mist1 is necessary for the establishment of granule organization in serous exocrine cells of the gastrointestinal tract. Mech Dev. 2004 Mar;121(3):261-72 |
1 | J:39063 Lemercier C, To RQ, Swanson BJ, Lyons GE, Konieczny SF, Mist1: a novel basic helix-loop-helix transcription factor exhibits a developmentally regulated expression pattern. Dev Biol. 1997 Feb 1;182(1):101-13 |
Bhlhb9 basic helix-loop-helix domain containing, class B9 (Synonyms: 2700087I09Rik) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Bhlhe22 basic helix-loop-helix family, member e22 (Synonyms: Beta3, Bhlhb5) | |
Results | Reference |
1 | J:162313 Bedogni F, Hodge RD, Elsen GE, Nelson BR, Daza RA, Beyer RP, Bammler TK, Rubenstein JL, Hevner RF, Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13129-34 |
1* | J:86963 Brunelli S, Innocenzi A, Cossu G, Bhlhb5 is expressed in the CNS and sensory organs during mouse embryonic development. Gene Expr Patterns. 2003 Dec;3(6):755-9 |
1 | J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489 |
1 | J:158273 Ross SE, Mardinly AR, McCord AE, Zurawski J, Cohen S, Jung C, Hu L, Mok SI, Shah A, Savner EM, Tolias C, Corfas R, Chen S, Inquimbert P, Xu Y, McInnes RR, Rice FL, Corfas G, Ma Q, Woolf CJ, Greenberg ME, Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice. Neuron. 2010 Mar 25;65(6):886-98 |
1 | J:182304 Ross SE, McCord AE, Jung C, Atan D, Mok SI, Hemberg M, Kim TK, Salogiannis J, Hu L, Cohen S, Lin Y, Harrar D, McInnes RR, Greenberg ME, Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly. Neuron. 2012 Jan 26;73(2):292-303 |
1 | J:278287 Tang T, Zhang Y, Wang Y, Cai Z, Lu Z, Li L, Huang R, Hagelkruys A, Matthias P, Zhang H, Seiser C, Xie Y, HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development. Neuron. 2019 Mar 20;101(6):1117-1133.e5 |
Bhlhe40 basic helix-loop-helix family, member e40 (Synonyms: Bhlhb2, C130042M06Rik, Clast5, CR8, cytokine response gene 8, DEC1, eip1 (E47 interaction protein 1), Sharp2, Stra13, Stra14) | |
Results | Reference |
1* | J:93152 Maclean HE, Kronenberg HM, Expression of Stra13 during mouse endochondral bone development. Gene Expr Patterns. 2004 Oct;4(6):633-6 |
Bhlhe41 basic helix-loop-helix family, member e41 (Synonyms: 6430520M22Rik, Bhlhb3, DEC2, Sharp1) | |
Results | Reference |
1* | J:178282 Azmi S, Sun H, Ozog A, Taneja R, mSharp-1/DEC2, a basic helix-loop-helix protein functions as a transcriptional repressor of E box activity and Stra13 expression. J Biol Chem. 2003 May 30;278(22):20098-109 |
1* | J:76821 Azmi S, Taneja R, Embryonic expression of mSharp-1/mDEC2, which encodes a basic helix-loop-helix transcription factor. Mech Dev. 2002 Jun;114(1-2):181 |
1* | J:316953 Suzuki M, Sato F, Bhawal UK, The basic helix-loop-helix (bHLH) transcription factor DEC2 negatively regulates Twist1 through an E-box element. Biochem Biophys Res Commun. 2014 Dec 12;455(3-4):390-5 |
Bhmt betaine-homocysteine methyltransferase | |
Results | Reference |
2* | J:308609 Sararols P, Stevant I, Neirijnck Y, Rebourcet D, Darbey A, Curley MK, Kuhne F, Dermitzakis E, Smith LB, Nef S, Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells. Front Cell Dev Biol. 2021;9:695546 |
Bicc1 BicC family RNA binding protein 1 (Synonyms: Bic-C, jcpk) | |
Results | Reference |
1* | J:214703 Lian P, Li A, Li Y, Liu H, Liang D, Hu B, Lin D, Jiang T, Moeckel G, Qin D, Wu G, Loss of polycystin-1 inhibits Bicc1 expression during mouse development. PLoS One. 2014;9(3):e88816 |
1 | J:158678 Tran U, Zakin L, Schweickert A, Agrawal R, Doger R, Blum M, De Robertis EM, Wessely O, The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity. Development. 2010 Apr;137(7):1107-16 |
Bicdl1 BICD family like cargo adaptor 1 (Synonyms: 2210403N09Rik, BICDR-1, Ccdc64) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Bik BCL2-interacting killer (Synonyms: Biklk, Blk, Nbk) | |
Results | Reference |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
Bin3 bridging integrator 3 (Synonyms: 1700015F07Rik) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
Birc2 baculoviral IAP repeat-containing 2 (Synonyms: Api1, C330006D17Rik, cIAP-1, cIAP1, HIAP1, IAP1, mcIAP1, MIAP1, MIHB) | |
Results | Reference |
1 | J:294981 Liu X, Castle V, Taketo T, Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development. Cell Death Dis. 2019 Oct 17;10(11):790 |
1 | J:329315 Sheldon C, Farley A, Ma Q, Pu WT, Lin Z, Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development. Cells. 2022 Sep 10;11(18) |
Birc3 baculoviral IAP repeat-containing 3 (Synonyms: Api2, cIAP-2, cIAP2, HIAP2, IAP2, MIAP2, MIHC, RNF49) | |
Results | Reference |
1 | J:294981 Liu X, Castle V, Taketo T, Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development. Cell Death Dis. 2019 Oct 17;10(11):790 |
Birc5 baculoviral IAP repeat-containing 5 (Synonyms: Api4, survivin, TIAP) | |
Results | Reference |
1 | J:306061 Damen M, Wirtz L, Soroka E, Khatif H, Kukat C, Simons BD, Bazzi H, High proliferation and delamination during skin epidermal stratification. Nat Commun. 2021 May 28;12(1):3227 |
1 | J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82 |
1 | J:290729 Grundl M, Walz S, Hauf L, Schwab M, Werner KM, Spahr S, Schulte C, Maric HM, Ade CP, Gaubatz S, Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes. PLoS Genet. 2020 May;16(5):e1008818 |
1 | J:294113 Lough KJ, Byrd KM, Descovich CP, Spitzer DC, Bergman AJ, Beaudoin GM 3rd, Reichardt LF, Williams SE, Telophase correction refines division orientation in stratified epithelia. Elife. 2019 Dec 13;8:e49249 |
1* | J:219386 Williams SE, Ratliff LA, Postiglione MP, Knoblich JA, Fuchs E, Par3-mInsc and Galphai3 cooperate to promote oriented epidermal cell divisions through LGN. Nat Cell Biol. 2014 Aug;16(8):758-69 |
Birc7 baculoviral IAP repeat-containing 7 (Synonyms: KIAP, Livin, ML-IAP) | |
Results | Reference |
2* | J:230953 De Maria A, Bassnett S, Birc7: A Late Fiber Gene of the Crystalline Lens. Invest Ophthalmol Vis Sci. 2015 Jul;56(8):4823-34 |
Blk B lymphoid kinase | |
Results | Reference |
1* | J:55945 Wang JP, Chuang SM, Shen CL, Chen ST, Expression of Src family during development of the mouse nervous system. Biomed Res. 1998 OCT;19(5):315-325 |
Blm Bloom syndrome, RecQ like helicase | |
Results | Reference |
1* | J:50843 Chester N, Kuo F, Kozak C, O'Hara CD, Leder P, Stage-specific apoptosis, developmental delay, and embryonic lethality in mice homozygous for a targeted disruption in the murine Bloom's syndrome gene. Genes Dev. 1998 Nov 1;12(21):3382-93 |
Bmal1 basic helix-loop-helix ARNT like 1 (Synonyms: Arnt3, Arntl, bHLHe5, MOP3) | |
Results | Reference |
1* | J:325107 Cao X, Yan Y, Luo X, Yang X, Cui H, Yang Y, Li H, Analyses of the circadian clock genes expression in whole embryos and maternal major tissues of mice. J Mol Histol. 2022 Apr;53(2):473-482 |
1* | J:158725 Dolatshad H, Cary AJ, Davis FC, Differential expression of the circadian clock in maternal and embryonic tissues of mice. PLoS One. 2010;5(3):e9855 |
1* | J:161413 Ratajczak CK, Herzog ED, Muglia LJ, Clock gene expression in gravid uterus and extra-embryonic tissues during late gestation in the mouse. Reprod Fertil Dev. 2010;22(5):743-50 |
2 | J:329949 Yuan H, Xie B, Yu X, Lin C, Li M, Zhang Y, Zou X, Lu M, Zhao M, Wen X, A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development. Front Physiol. 2022;13:981311 |
Bmf BCL2 modifying factor | |
Results | Reference |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
Bmi1 Bmi1 polycomb ring finger oncogene (Synonyms: Bmi-1, Bmi1, Pcgf4) | |
Results | Reference |
1* | J:38105 Alkema MJ, Bronk M, Verhoeven E, Otte A, van't Veer LJ, Berns A, van Lohuizen M, Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian polycomb complex. Genes Dev. 1997 Jan 15;11(2):226-40 |
1* | J:47794 Hashimoto N, Brock HW, Nomura M, Kyba M, Hodgson J, Fujita Y, Takihara Y, Shimada K, Higashinakagawa T, RAE28, BMI1, and M33 are members of heterogeneous multimeric mammalian Polycomb group complexes. Biochem Biophys Res Commun. 1998 Apr 17;245(2):356-65 |
1* | J:170274 Li L, Kwon HJ, Harada H, Ohshima H, Cho SW, Jung HS, Expression patterns of ABCG2, Bmi-1, Oct-3/4, and Yap in the developing mouse incisor. Gene Expr Patterns. 2011 Mar-Apr;11(3-4):163-70 |
Bmp1 bone morphogenetic protein 1 | |
Results | Reference |
2* | J:17981 Fukagawa M, Suzuki N, Hogan BL, Jones CM, Embryonic expression of mouse bone morphogenetic protein-1 (BMP-1), which is related to the Drosophila dorsoventral gene tolloid and encodes a putative astacin metalloendopeptidase. Dev Biol. 1994 May;163(1):175-83 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
Bmp2 bone morphogenetic protein 2 (Synonyms: Bmp2a) | |
Results | Reference |
1* | J:74162 Abdelwahid E, Rice D, Pelliniemi LJ, Jokinen E, Overlapping and differential localization of Bmp-2, Bmp-4, Msx-2 and apoptosis in the endocardial cushion and adjacent tissues of the developing mouse heart. Cell Tissue Res. 2001 Jul;305(1):67-78 |
1 | J:44411 Aberg T, Wozney J, Thesleff I, Expression patterns of bone morphogenetic proteins (Bmps) in the developing mouse tooth suggest roles in morphogenesis and cell differentiation. Dev Dyn. 1997 Dec;210(4):383-96 |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1* | J:29671 Bitgood MJ, McMahon AP, Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev Biol. 1995 Nov;172(1):126-38 |
1 | J:126342 Bok J, Brunet LJ, Howard O, Burton Q, Wu DK, Role of hindbrain in inner ear morphogenesis: Analysis of Noggin knockout mice. Dev Biol. 2007 Nov 1;311(1):69-78 |
1 | J:320322 Chen WC, Zhang Y, Ma D, Ma XJ, Shou WN, Huang GY, Bmp2 regulates the interaction between EPDCs and myocytes in cardiac OFT. Med Hypotheses. 2012 Aug;79(2):174-7 |
1 | J:217500 Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D, Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60 |
1 | J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400 |
2 | J:164103 Du Y, Xiao Q, Yip HK, Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the smad/id cascade. Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3764-73 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:356109 Ge W, Tan SJ, Wang SH, Li L, Sun XF, Shen W, Wang X, Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development. Theranostics. 2020;10(17):7581-7598 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1 | J:252755 Gillers BS, Chiplunkar A, Aly H, Valenta T, Basler K, Christoffels VM, Efimov IR, Boukens BJ, Rentschler S, Canonical wnt signaling regulates atrioventricular junction programming and electrophysiological properties. Circ Res. 2015 Jan 30;116(3):398-406 |
1 | J:74145 Gori F, Schipani E, Demay MB, Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development. J Cell Biochem. 2001 Apr 2-27;82(1):46-57 |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:156945 Hwang CH, Guo D, Harris MA, Howard O, Mishina Y, Gan L, Harris SE, Wu DK, Role of bone morphogenetic proteins on cochlear hair cell formation: analyses of Noggin and Bmp2 mutant mice. Dev Dyn. 2010 Feb;239(2):505-13 |
1* | J:132023 Hwang CH, Wu DK, Noggin heterozygous mice: an animal model for congenital conductive hearing loss in humans. Hum Mol Genet. 2008 Mar 15;17(6):844-53 |
1 | J:260962 Kamiunten T, Ideno H, Shimada A, Arai Y, Terashima T, Tomooka Y, Nakamura Y, Nakashima K, Kimura H, Shinkai Y, Tachibana M, Nifuji A, Essential roles of G9a in cell proliferation and differentiation during tooth development. Exp Cell Res. 2017 Aug 15;357(2):202-210 |
1 | J:54912 Karlsson L, Bondjers C, Betsholtz C, Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle. Development. 1999 Jun;126(12):2611-21 |
1* | J:168597 Kashimada K, Pelosi E, Chen H, Schlessinger D, Wilhelm D, Koopman P, FOXL2 and BMP2 act cooperatively to regulate follistatin gene expression during ovarian development. Endocrinology. 2011 Jan;152(1):272-80 |
1 | J:265947 Kawasaki M, Kawasaki K, Meguro F, Yamada A, Ishikawa R, Porntaveetus T, Blackburn J, Otsuka-Tanaka Y, Saito N, Ota MS, Sharpe PT, Kessler JA, Herz J, Cobourne MT, Maeda T, Ohazama A, Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms. PLoS One. 2018;13(9):e0204126 |
1* | J:116785 Kettunen P, Nie X, Kvinnsland IH, Luukko K, Histological development and dynamic expression of Bmp2-6 mRNAs in the embryonic and postnatal mouse cranial base. Anat Rec A Discov Mol Cell Evol Biol. 2006 Dec;288(12):1250-8 |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1 | J:182649 Levi B, James AW, Nelson ER, Brugmann SA, Sorkin M, Manu A, Longaker MT, Role of Indian hedgehog signaling in palatal osteogenesis. Plast Reconstr Surg. 2011 Mar;127(3):1182-90 |
1 | J:246806 Li Y, Zhang L, Hu Y, Chen M, Han F, Qin Y, Chen M, Cui X, Duo S, Tang F, Gao F, beta-Catenin directs the transformation of testis Sertoli cells to ovarian granulosa-like cells by inducing Foxl2 expression. J Biol Chem. 2017 Oct 27;292(43):17577-17586 |
1* | J:63337 Lu H, Jin Y, Tipoe GL, Alteration in the expression of bone morphogenetic protein-2,3,4,5 mRNA during pathogenesis of cleft palate in BALB/c mice. Arch Oral Biol. 2000 Feb;45(2):133-40 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1* | J:32952 Lyons KM, Pelton RW, Hogan BL, Organogenesis and pattern formation in the mouse: RNA distribution patterns suggest a role for bone morphogenetic protein-2A (BMP-2A). Development. 1990 Aug;109(4):833-44 |
1* | J:276706 Meguro F, Porntaveetus T, Kawasaki M, Kawasaki K, Yamada A, Kakihara Y, Saeki M, Tabeta K, Kessler JA, Maeda T, Ohazama A, Bmp signaling in molar cusp formation. Gene Expr Patterns. 2019 Jun;32:67-71 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1* | J:237529 Salazar VS, Ohte S, Capelo LP, Gamer L, Rosen V, Specification of osteoblast cell fate by canonical Wnt signaling requires Bmp2. Development. 2016 Dec 01;143(23):4352-4367 |
1 | J:48561 Solloway MJ, Dudley AT, Bikoff EK, Lyons KM, Hogan BL, Robertson EJ, Mice lacking Bmp6 function. Dev Genet. 1998;22(4):321-39 |
1 | J:144194 Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72 |
1 | J:31907 Vainio S, Karavanova I, Jowett A, Thesleff I, Identification of BMP-4 as a signal mediating secondary induction between epithelial and mesenchymal tissues during early tooth development. Cell. 1993 Oct 8;75(1):45-58 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:91704 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Wankell M, Werner S, Thesleff I, Modulation of activin/bone morphogenetic protein signaling by follistatin is required for the morphogenesis of mouse molar teeth. Dev Dyn. 2004 Sep;231(1):98-108 |
1 | J:94518 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Werner S, Thesleff I, Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation. Dev Cell. 2004 Nov;7(5):719-30 |
1* | J:200760 Wang Y, Zheng Y, Chen D, Chen Y, Enhanced BMP signaling prevents degeneration and leads to endochondral ossification of Meckel's cartilage in mice. Dev Biol. 2013 Sep 15;381(2):301-11 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
1 | J:315014 Zhou C, Chen D, Ren J, Huang D, Li R, Luo H, Guan C, Cao Y, Wang W, FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex. J Cell Mol Med. 2021 Mar;25(6):3051-3062 |
2 | J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687 |
Bmp2k BMP2 inducible kinase (Synonyms: 4933417M22Rik, BIKE) | |
Results | Reference |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
Bmp3 bone morphogenetic protein 3 (Synonyms: 9530029I04Rik) | |
Results | Reference |
1 | J:44411 Aberg T, Wozney J, Thesleff I, Expression patterns of bone morphogenetic proteins (Bmps) in the developing mouse tooth suggest roles in morphogenesis and cell differentiation. Dev Dyn. 1997 Dec;210(4):383-96 |
1 | J:151466 Gamer LW, Cox K, Carlo JM, Rosen V, Overexpression of BMP3 in the developing skeleton alters endochondral bone formation resulting in spontaneous rib fractures. Dev Dyn. 2009 Aug 3;238(9):2374-2381 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:327415 Jing J, Feng J, Yuan Y, Guo T, Lei J, Pei F, Ho TV, Chai Y, Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022 Aug 16;13(1):4803 |
1* | J:116785 Kettunen P, Nie X, Kvinnsland IH, Luukko K, Histological development and dynamic expression of Bmp2-6 mRNAs in the embryonic and postnatal mouse cranial base. Anat Rec A Discov Mol Cell Evol Biol. 2006 Dec;288(12):1250-8 |
1* | J:63337 Lu H, Jin Y, Tipoe GL, Alteration in the expression of bone morphogenetic protein-2,3,4,5 mRNA during pathogenesis of cleft palate in BALB/c mice. Arch Oral Biol. 2000 Feb;45(2):133-40 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:48561 Solloway MJ, Dudley AT, Bikoff EK, Lyons KM, Hogan BL, Robertson EJ, Mice lacking Bmp6 function. Dev Genet. 1998;22(4):321-39 |
Bmp4 bone morphogenetic protein 4 (Synonyms: Bmp2b, Bmp2b-1, Bmp2b1, Bmp-4) | |
Results | Reference |
1* | J:74162 Abdelwahid E, Rice D, Pelliniemi LJ, Jokinen E, Overlapping and differential localization of Bmp-2, Bmp-4, Msx-2 and apoptosis in the endocardial cushion and adjacent tissues of the developing mouse heart. Cell Tissue Res. 2001 Jul;305(1):67-78 |
1 | J:44411 Aberg T, Wozney J, Thesleff I, Expression patterns of bone morphogenetic proteins (Bmps) in the developing mouse tooth suggest roles in morphogenesis and cell differentiation. Dev Dyn. 1997 Dec;210(4):383-96 |
1 | J:350005 Adasooriya D, Jeong JK, Kyeong M, Kan S, Kim J, Cho ES, Cho SW, Notum regulates the cusp and root patterns in mouse molar. Sci Rep. 2024 Jun 13;14(1):13633 |
2 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
1 | J:176604 Bell SM, Zhang L, Mendell A, Xu Y, Haitchi HM, Lessard JL, Whitsett JA, Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. Dev Biol. 2011 Oct 1;358(1):79-90 |
1* | J:38383 Bellusci S, Furuta Y, Rush MG, Henderson R, Winnier G, Hogan BL, Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis. Development. 1997 Jan;124(1):53-63 |
1* | J:88802 Berman DM, Desai N, Wang X, Karhadkar SS, Reynon M, Abate-Shen C, Beachy PA, Shen MM, Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis. Dev Biol. 2004 Mar 15;267(2):387-98 |
1* | J:29671 Bitgood MJ, McMahon AP, Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev Biol. 1995 Nov;172(1):126-38 |
1 | J:156015 Blitz E, Viukov S, Sharir A, Shwartz Y, Galloway JL, Pryce BA, Johnson RL, Tabin CJ, Schweitzer R, Zelzer E, Bone ridge patterning during musculoskeletal assembly is mediated through SCX regulation of Bmp4 at the tendon-skeleton junction. Dev Cell. 2009 Dec;17(6):861-73 |
1 | J:126342 Bok J, Brunet LJ, Howard O, Burton Q, Wu DK, Role of hindbrain in inner ear morphogenesis: Analysis of Noggin knockout mice. Dev Biol. 2007 Nov 1;311(1):69-78 |
1 | J:197180 Buniello A, Hardisty-Hughes RE, Pass JC, Bober E, Smith RJ, Steel KP, Headbobber: a combined morphogenetic and cochleosaccular mouse model to study 10qter deletions in human deafness. PLoS One. 2013;8(2):e56274 |
1 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1 | J:111051 Cui CY, Hashimoto T, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9142-7 |
1 | J:217500 Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D, Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60 |
1 | J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400 |
1 | J:215675 Deng M, Luo XJ, Pan L, Yang H, Xie X, Liang G, Huang L, Hu F, Kiernan AE, Gan L, LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea. J Neurosci. 2014 Jul 23;34(30):10072-7 |
2 | J:164103 Du Y, Xiao Q, Yip HK, Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the smad/id cascade. Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3764-73 |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1* | J:67309 Grotewold L, Plum M, Dildrop R, Peters T, Ruther U, Bambi is coexpressed with Bmp-4 during mouse embryogenesis. Mech Dev. 2001 Feb;100(2):327-30 |
1 | J:239666 Hagglund AC, Jones I, Carlsson L, A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development. Dis Model Mech. 2017 Mar 01;10(3):245-257 |
1* | J:82630 Hall JM, Bell ML, Finger TE, Disruption of sonic hedgehog signaling alters growth and patterning of lingual taste papillae. Dev Biol. 2003 Mar 15;255(2):263-77 |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:193958 Huh SH, Narhi K, Lindfors PH, Haara O, Yang L, Ornitz DM, Mikkola ML, Fgf20 governs formation of primary and secondary dermal condensations in developing hair follicles. Genes Dev. 2013 Feb 15;27(4):450-8 |
1* | J:156945 Hwang CH, Guo D, Harris MA, Howard O, Mishina Y, Gan L, Harris SE, Wu DK, Role of bone morphogenetic proteins on cochlear hair cell formation: analyses of Noggin and Bmp2 mutant mice. Dev Dyn. 2010 Feb;239(2):505-13 |
1* | J:132023 Hwang CH, Wu DK, Noggin heterozygous mice: an animal model for congenital conductive hearing loss in humans. Hum Mol Genet. 2008 Mar 15;17(6):844-53 |
2 | J:200638 Islam SS, Mokhtari RB, Kumar S, Maalouf J, Arab S, Yeger H, Farhat WA, Spatio-temporal distribution of Smads and role of Smads/TGF-beta/BMP-4 in the regulation of mouse bladder organogenesis. PLoS One. 2013;8(4):e61340 |
1 | J:108713 Itaranta P, Chi L, Seppanen T, Niku M, Tuukkanen J, Peltoketo H, Vainio S, Wnt-4 signaling is involved in the control of smooth muscle cell fate via Bmp-4 in the medullary stroma of the developing kidney. Dev Biol. 2006 May 15;293(2):473-83 |
1* | J:159629 Jang CW, Gao L, Dickinson ME, Behringer RR, Bmp4-directed nuclear cyan fluorescent protein provides a tool for live imaging and reveals cellular resolution of Bmp4 expression patterns during embryogenesis. Int J Dev Biol. 2010;54(5):931-8 |
1 | J:275123 Jenkins BA, Fontecilla NM, Lu CP, Fuchs E, Lumpkin EA, The cellular basis of mechanosensory Merkel-cell innervation during development. Elife. 2019 Feb 22;8:e42633 |
1 | J:233686 Jia WJ, Jiang S, Tang QL, Shen D, Xue B, Ning W, Li CJ, Geranylgeranyl Diphosphate Synthase Modulates Fetal Lung Branching Morphogenesis Possibly through Controlling K-Ras Prenylation. Am J Pathol. 2016 Jun;186(6):1454-65 |
1 | J:235517 Kam JW, Dumontier E, Baim C, Brignall AC, Mendes da Silva D, Cowan M, Kennedy TE, Cloutier JF, RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016 May 1;143(9):1534-46 |
1 | J:260962 Kamiunten T, Ideno H, Shimada A, Arai Y, Terashima T, Tomooka Y, Nakamura Y, Nakashima K, Kimura H, Shinkai Y, Tachibana M, Nifuji A, Essential roles of G9a in cell proliferation and differentiation during tooth development. Exp Cell Res. 2017 Aug 15;357(2):202-210 |
1 | J:54912 Karlsson L, Bondjers C, Betsholtz C, Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle. Development. 1999 Jun;126(12):2611-21 |
1 | J:295492 Kawai M, Herrmann D, Fuchs A, Cheng S, Ferrer-Vaquer A, Gotz R, Driller K, Neubuser A, Ohura K, Fgfr1 conditional-knockout in neural crest cells induces heterotopic chondrogenesis and osteogenesis in mouse frontal bones. Med Mol Morphol. 2019 Sep;52(3):156-163 |
1 | J:265947 Kawasaki M, Kawasaki K, Meguro F, Yamada A, Ishikawa R, Porntaveetus T, Blackburn J, Otsuka-Tanaka Y, Saito N, Ota MS, Sharpe PT, Kessler JA, Herz J, Cobourne MT, Maeda T, Ohazama A, Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms. PLoS One. 2018;13(9):e0204126 |
1 | J:51084 Keranen SV, Aberg T, Kettunen P, Thesleff I, Jernvall J, Association of developmental regulatory genes with the development of different molar tooth shapes in two species of rodents. Dev Genes Evol. 1998 Nov;208(9):477-86 |
1* | J:116785 Kettunen P, Nie X, Kvinnsland IH, Luukko K, Histological development and dynamic expression of Bmp2-6 mRNAs in the embryonic and postnatal mouse cranial base. Anat Rec A Discov Mol Cell Evol Biol. 2006 Dec;288(12):1250-8 |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1 | J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670 |
1 | J:78990 Lamm ML, Catbagan WS, Laciak RJ, Barnett DH, Hebner CM, Gaffield W, Walterhouse D, Iannaccone P, Bushman W, Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation. Dev Biol. 2002 Sep 15;249(2):349-66 |
1 | J:69382 Lamm ML, Podlasek CA, Barnett DH, Lee J, Clemens JQ, Hebner CM, Bushman W, Mesenchymal factor bone morphogenetic protein 4 restricts ductal budding and branching morphogenesis in the developing prostate. Dev Biol. 2001 Apr 15;232(2):301-14 |
1 | J:214993 Lin C, Chen MH, Yao E, Song H, Gacayan R, Hui CC, Chuang PT, Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development. Dev Biol. 2014 Aug 15;392(2):324-33 |
1* | J:63337 Lu H, Jin Y, Tipoe GL, Alteration in the expression of bone morphogenetic protein-2,3,4,5 mRNA during pathogenesis of cleft palate in BALB/c mice. Arch Oral Biol. 2000 Feb;45(2):133-40 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:243772 Mamo TM, Wittern AB, Kleppa MJ, Bohnenpoll T, Weiss AC, Kispert A, BMP4 uses several different effector pathways to regulate proliferation and differentiation in the epithelial and mesenchymal tissue compartments of the developing mouse ureter. Hum Mol Genet. 2017 Sep 15;26(18):3553-3563 |
1* | J:276706 Meguro F, Porntaveetus T, Kawasaki M, Kawasaki K, Yamada A, Kakihara Y, Saeki M, Tabeta K, Kessler JA, Maeda T, Ohazama A, Bmp signaling in molar cusp formation. Gene Expr Patterns. 2019 Jun;32:67-71 |
1 | J:180393 Miletich I, Yu WY, Zhang R, Yang K, Caixeta de Andrade S, Pereira SF, Ohazama A, Mock OB, Buchner G, Sealby J, Webster Z, Zhao M, Bei M, Sharpe PT, Developmental stalling and organ-autonomous regulation of morphogenesis. Proc Natl Acad Sci U S A. 2011 Nov 29;108(48):19270-5 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
1* | J:297164 Nie X, Zheng J, Cruciger M, Yang P, Mao JJ, mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev Biol. 2020 Nov 1;467(1-2):77-87 |
1 | J:144348 Ohazama A, Johnson EB, Ota MS, Choi HJ, Porntaveetus T, Oommen S, Itoh N, Eto K, Gritli-Linde A, Herz J, Sharpe PT, Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One. 2008;3(12):e4092 |
1 | J:201076 Okano T, Kelley MW, Expression of insulin-like growth factor binding proteins during mouse cochlear development. Dev Dyn. 2013 Oct;242(10):1210-21 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1* | J:85732 Petiot A, Conti FJ, Grose R, Revest JM, Hodivala-Dilke KM, Dickson C, A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning. Development. 2003 Nov;130(22):5493-501 |
1 | J:51967 Podlasek CA, Seo RM, Clemens JQ, Ma L, Maas RL, Bushman W, Hoxa-10 deficient male mice exhibit abnormal development of the accessory sex organs. Dev Dyn. 1999 Jan;214(1):1-12 |
2 | J:136155 Porayette P, Paulson RF, BMP4/Smad5 dependent stress erythropoiesis is required for the expansion of erythroid progenitors during fetal development. Dev Biol. 2008 May 1;317(1):24-35 |
1 | J:286655 Sakamoto S, Tateya T, Omori K, Kageyama R, Id genes are required for morphogenesis and cellular patterning in the developing mammalian cochlea. Dev Biol. 2020 Apr 15;460(2):164-175 |
2* | J:85949 Shikama N, Lutz W, Kretzschmar R, Sauter N, Roth JF, Marino S, Wittwer J, Scheidweiler A, Eckner R, Essential function of p300 acetyltransferase activity in heart, lung and small intestine formation. EMBO J. 2003 Oct 1;22(19):5175-85 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:99391 Shu W, Guttentag S, Wang Z, Andl T, Ballard P, Lu MM, Piccolo S, Birchmeier W, Whitsett JA, Millar SE, Morrisey EE, Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung. Dev Biol. 2005 Jul 1;283(1):226-39 |
1 | J:48561 Solloway MJ, Dudley AT, Bikoff EK, Lyons KM, Hogan BL, Robertson EJ, Mice lacking Bmp6 function. Dev Genet. 1998;22(4):321-39 |
1 | J:361958 Straube P, Beckers A, Jany UWH, Bergmann F, Ludtke TH, Rudat C, Trowe MO, Peters I, Klopf MG, Mamo TM, Kispert A, Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter. Development. 2025 Feb 1;152(3) |
1 | J:194779 Tao J, Koster MI, Harrison W, Moran JL, Beier DR, Roop DR, Overbeek PA, A spontaneous Fatp4/Scl27a4 splice site mutation in a new murine model for congenital ichthyosis. PLoS One. 2012;7(11):e50634 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1 | J:159209 Tornqvist G, Sandberg A, Hagglund AC, Carlsson L, Cyclic expression of lhx2 regulates hair formation. PLoS Genet. 2010;6(4):e1000904 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:161451 Villavicencio-Lorini P, Kuss P, Friedrich J, Haupt J, Farooq M, Turkmen S, Duboule D, Hecht J, Mundlos S, Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. J Clin Invest. 2010 Jun 1;120(6):1994-2004 |
2 | J:256746 Wang X, Shan X, Gregory-Evans CY, A mouse model of aniridia reveals the in vivo downstream targets of Pax6 driving iris and ciliary body development in the eye. Biochim Biophys Acta. 2017 Jan;1863(1):60-67 |
1 | J:91704 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Wankell M, Werner S, Thesleff I, Modulation of activin/bone morphogenetic protein signaling by follistatin is required for the morphogenesis of mouse molar teeth. Dev Dyn. 2004 Sep;231(1):98-108 |
1 | J:94518 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Werner S, Thesleff I, Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation. Dev Cell. 2004 Nov;7(5):719-30 |
1* | J:200760 Wang Y, Zheng Y, Chen D, Chen Y, Enhanced BMP signaling prevents degeneration and leads to endochondral ossification of Meckel's cartilage in mice. Dev Biol. 2013 Sep 15;381(2):301-11 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
1 | J:217590 Yuan G, Yang G, Zheng Y, Zhu X, Chen Z, Zhang Z, Chen Y, The non-canonical BMP and Wnt/beta-catenin signaling pathways orchestrate early tooth development. Development. 2015 Jan 1;142(1):128-39 |
1* | J:77380 Zhang J, Tan X, Contag CH, Lu Y, Guo D, Harris SE, Feng JQ, Dissection of promoter control modules that direct Bmp4 expression in the epithelium-derived components of hair follicles. Biochem Biophys Res Commun. 2002 May 24;293(5):1412-9 |
1* | J:87163 Zhang Z, Song Y, Zhang X, Tang J, Chen J, Chen Y, Msx1/Bmp4 genetic pathway regulates mammalian alveolar bone formation via induction of Dlx5 and Cbfa1. Mech Dev. 2003 Dec;120(12):1469-79 |
1* | J:173972 Zhao H, Li S, Han D, Kaartinen V, Chai Y, Alk5-mediated transforming growth factor beta signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol. 2011 May;31(10):2079-89 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
2 | J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687 |
Bmp5 bone morphogenetic protein 5 | |
Results | Reference |
1 | J:44411 Aberg T, Wozney J, Thesleff I, Expression patterns of bone morphogenetic proteins (Bmps) in the developing mouse tooth suggest roles in morphogenesis and cell differentiation. Dev Dyn. 1997 Dec;210(4):383-96 |
1 | J:265947 Kawasaki M, Kawasaki K, Meguro F, Yamada A, Ishikawa R, Porntaveetus T, Blackburn J, Otsuka-Tanaka Y, Saito N, Ota MS, Sharpe PT, Kessler JA, Herz J, Cobourne MT, Maeda T, Ohazama A, Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms. PLoS One. 2018;13(9):e0204126 |
1* | J:116785 Kettunen P, Nie X, Kvinnsland IH, Luukko K, Histological development and dynamic expression of Bmp2-6 mRNAs in the embryonic and postnatal mouse cranial base. Anat Rec A Discov Mol Cell Evol Biol. 2006 Dec;288(12):1250-8 |
1* | J:21484 King JA, Marker PC, Seung KJ, Kingsley DM, BMP5 and the molecular, skeletal, and soft-tissue alterations in short ear mice. Dev Biol. 1994 Nov;166(1):112-22 |
1* | J:63337 Lu H, Jin Y, Tipoe GL, Alteration in the expression of bone morphogenetic protein-2,3,4,5 mRNA during pathogenesis of cleft palate in BALB/c mice. Arch Oral Biol. 2000 Feb;45(2):133-40 |
1 | J:48561 Solloway MJ, Dudley AT, Bikoff EK, Lyons KM, Hogan BL, Robertson EJ, Mice lacking Bmp6 function. Dev Genet. 1998;22(4):321-39 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
Bmp6 bone morphogenetic protein 6 (Synonyms: D13Wsu115e, Vgr1) | |
Results | Reference |
1 | J:44411 Aberg T, Wozney J, Thesleff I, Expression patterns of bone morphogenetic proteins (Bmps) in the developing mouse tooth suggest roles in morphogenesis and cell differentiation. Dev Dyn. 1997 Dec;210(4):383-96 |
1 | J:235552 Chinn GA, Hirokawa KE, Chuang TM, Urbina C, Patel F, Fong J, Funatsu N, Monuki ES, Agenesis of the Corpus Callosum Due to Defective Glial Wedge Formation in Lhx2 Mutant Mice. Cereb Cortex. 2015 Sep;25(9):2707-18 |
1* | J:66902 Colnot C, Sidhu SS, Balmain N, Poirier F, Uncoupling of chondrocyte death and vascular invasion in mouse galectin 3 null mutant bones. Dev Biol. 2001 Jan 1;229(1):203-14 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:235517 Kam JW, Dumontier E, Baim C, Brignall AC, Mendes da Silva D, Cowan M, Kennedy TE, Cloutier JF, RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016 May 1;143(9):1534-46 |
1* | J:116785 Kettunen P, Nie X, Kvinnsland IH, Luukko K, Histological development and dynamic expression of Bmp2-6 mRNAs in the embryonic and postnatal mouse cranial base. Anat Rec A Discov Mol Cell Evol Biol. 2006 Dec;288(12):1250-8 |
1 | J:70365 Kim RY, Robertson EJ, Solloway MJ, Bmp6 and Bmp7 are required for cushion formation and septation in the developing mouse heart. Dev Biol. 2001 Jul 15;235(2):449-66 |
1* | J:9842 Lyons K, Graycar JL, Lee A, Hashmi S, Lindquist PB, Chen EY, Hogan BL, Derynck R, Vgr-1, a mammalian gene related to Xenopus Vg-1, is a member of the transforming growth factor beta gene superfamily. Proc Natl Acad Sci U S A. 1989 Jun;86(12):4554-8 |
1* | J:15320 Lyons KM, Pelton RW, Hogan BL, Patterns of expression of murine Vgr-1 and BMP-2a RNA suggest that transforming growth factor-beta-like genes coordinately regulate aspects of embryonic development. Genes Dev. 1989 Nov;3(11):1657-68 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:48561 Solloway MJ, Dudley AT, Bikoff EK, Lyons KM, Hogan BL, Robertson EJ, Mice lacking Bmp6 function. Dev Genet. 1998;22(4):321-39 |
1* | J:239142 Wall NA, Blessing M, Wright CV, Hogan BL, Biosynthesis and in vivo localization of the decapentaplegic-Vg-related protein, DVR-6 (bone morphogenetic protein-6). J Cell Biol. 1993 Jan;120(2):493-502 |
Bmp7 bone morphogenetic protein 7 (Synonyms: OP1, osteogenic protein 1) | |
Results | Reference |
1 | J:44411 Aberg T, Wozney J, Thesleff I, Expression patterns of bone morphogenetic proteins (Bmps) in the developing mouse tooth suggest roles in morphogenesis and cell differentiation. Dev Dyn. 1997 Dec;210(4):383-96 |
1 | J:196652 Choe Y, Kozlova A, Graf D, Pleasure SJ, Bone morphogenic protein signaling is a major determinant of dentate development. J Neurosci. 2013 Apr 17;33(16):6766-75 |
1 | J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400 |
2 | J:164103 Du Y, Xiao Q, Yip HK, Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the smad/id cascade. Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3764-73 |
1 | J:30057 Dudley AT, Lyons KM, Robertson EJ, A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev. 1995 NOV 15;9(22):2795-2807 |
1 | J:143603 Esibizione D, Cui CY, Schlessinger D, Candidate EDA targets revealed by expression profiling of primary keratinocytes from Tabby mutant mice. Gene. 2008 Dec 31;427(1-2):42-6 |
1 | J:104840 Grishina IB, Kim SY, Ferrara C, Makarenkova HP, Walden PD, BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling. Dev Biol. 2005 Dec 15;288(2):334-47 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:156945 Hwang CH, Guo D, Harris MA, Howard O, Mishina Y, Gan L, Harris SE, Wu DK, Role of bone morphogenetic proteins on cochlear hair cell formation: analyses of Noggin and Bmp2 mutant mice. Dev Dyn. 2010 Feb;239(2):505-13 |
1* | J:132023 Hwang CH, Wu DK, Noggin heterozygous mice: an animal model for congenital conductive hearing loss in humans. Hum Mol Genet. 2008 Mar 15;17(6):844-53 |
1 | J:235517 Kam JW, Dumontier E, Baim C, Brignall AC, Mendes da Silva D, Cowan M, Kennedy TE, Cloutier JF, RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016 May 1;143(9):1534-46 |
1 | J:265947 Kawasaki M, Kawasaki K, Meguro F, Yamada A, Ishikawa R, Porntaveetus T, Blackburn J, Otsuka-Tanaka Y, Saito N, Ota MS, Sharpe PT, Kessler JA, Herz J, Cobourne MT, Maeda T, Ohazama A, Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms. PLoS One. 2018;13(9):e0204126 |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1 | J:70365 Kim RY, Robertson EJ, Solloway MJ, Bmp6 and Bmp7 are required for cushion formation and septation in the developing mouse heart. Dev Biol. 2001 Jul 15;235(2):449-66 |
1 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
1* | J:67157 McCright B, Gao X, Shen L, Lozier J, Lan Y, Maguire M, Herzlinger D, Weinmaster G, Jiang R, Gridley T, Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development. 2001 Feb;128(4):491-502 |
1* | J:276706 Meguro F, Porntaveetus T, Kawasaki M, Kawasaki K, Yamada A, Kakihara Y, Saeki M, Tabeta K, Kessler JA, Maeda T, Ohazama A, Bmp signaling in molar cusp formation. Gene Expr Patterns. 2019 Jun;32:67-71 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:144348 Ohazama A, Johnson EB, Ota MS, Choi HJ, Porntaveetus T, Oommen S, Itoh N, Eto K, Gritli-Linde A, Herz J, Sharpe PT, Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One. 2008;3(12):e4092 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1 | J:241756 Sanchez-Camacho C, Ortega JA, Ocana I, Alcantara S, Bovolenta P, Appropriate Bmp7 levels are required for the differentiation of midline guidepost cells involved in corpus callosum formation. Dev Neurobiol. 2011 May;71(5):337-50 |
1 | J:48561 Solloway MJ, Dudley AT, Bikoff EK, Lyons KM, Hogan BL, Robertson EJ, Mice lacking Bmp6 function. Dev Genet. 1998;22(4):321-39 |
1 | J:326979 Taglienti M, Graf D, Schumacher V, Kreidberg JA, Bmp7 drives proximal tubule expansion and determines nephron number in the developing kidney. Development. 2022 Jul 15;149(14):dev200773 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:91704 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Wankell M, Werner S, Thesleff I, Modulation of activin/bone morphogenetic protein signaling by follistatin is required for the morphogenesis of mouse molar teeth. Dev Dyn. 2004 Sep;231(1):98-108 |
1 | J:94518 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Werner S, Thesleff I, Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation. Dev Cell. 2004 Nov;7(5):719-30 |
1* | J:200760 Wang Y, Zheng Y, Chen D, Chen Y, Enhanced BMP signaling prevents degeneration and leads to endochondral ossification of Meckel's cartilage in mice. Dev Biol. 2013 Sep 15;381(2):301-11 |
1 | J:149459 Wuelling M, Kaiser FJ, Buelens LA, Braunholz D, Shivdasani RA, Depping R, Vortkamp A, Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. Dev Biol. 2009 Apr 1;328(1):40-53 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
1* | J:173972 Zhao H, Li S, Han D, Kaartinen V, Chai Y, Alk5-mediated transforming growth factor beta signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol. 2011 May;31(10):2079-89 |
2 | J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687 |
1 | J:148972 Zouvelou V, Luder HU, Mitsiadis TA, Graf D, Deletion of BMP7 affects the development of bones, teeth, and other ectodermal appendages of the orofacial complex. J Exp Zoolog B Mol Dev Evol. 2009 Jan 6;312B(4):361-374 |
2 | J:149134 Zouvelou V, Passa O, Segklia K, Tsalavos S, Valenzuela DM, Economides AN, Graf D, Generation and functional characterization of mice with a conditional BMP7 allele. Int J Dev Biol. 2009;53(4):597-603 |
Bmp8b bone morphogenetic protein 8b (Synonyms: Op3) | |
Results | Reference |
1 | J:34634 Zhao GQ, Hogan BL, Evidence that mouse Bmp8a (Op2) and Bmp8b are duplicated genes that play a role in spermatogenesis and placental development. Mech Dev. 1996 Jul;57(2):159-68 |
Bmp10 bone morphogenetic protein 10 (Synonyms: b2b2711Clo) | |
Results | Reference |
1 | J:89476 Chen H, Shi S, Acosta L, Li W, Lu J, Bao S, Chen Z, Yang Z, Schneider MD, Chien KR, Conway SJ, Yoder MC, Haneline LS, Franco D, Shou W, BMP10 is essential for maintaining cardiac growth during murine cardiogenesis. Development. 2004 May;131(9):2219-31 |
1 | J:267108 Cho E, Mysliwiec MR, Carlson CD, Ansari A, Schwartz RJ, Lee Y, Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development. J Biol Chem. 2018 Jul 27;293(30):11659-11673 |
1 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
1 | J:192707 He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, Pu WT, Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res. 2012 Feb 3;110(3):406-15 |
1 | J:269446 Salguero-Jimenez A, Grego-Bessa J, D'Amato G, Jimenez-Borreguero LJ, de la Pompa JL, Myocardial Notch1-Rbpj deletion does not affect NOTCH signaling, heart development or function. PLoS One. 2018;13(12):e0203100 |
Bmper BMP-binding endothelial regulator (Synonyms: 3110056H04Rik, Crim3, crossveinless-2, Cv2, CV-2) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Bmpr1a bone morphogenetic protein receptor, type 1A (Synonyms: 1110037I22Rik, ALK3, Bmpr, BMPR-IA) | |
Results | Reference |
1 | J:170583 Baek JA, Lan Y, Liu H, Maltby KM, Mishina Y, Jiang R, Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation. Dev Biol. 2011 Feb 15;350(2):520-31 |
1 | J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82 |
1 | J:104840 Grishina IB, Kim SY, Ferrara C, Makarenkova HP, Walden PD, BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling. Dev Biol. 2005 Dec 15;288(2):334-47 |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:168597 Kashimada K, Pelosi E, Chen H, Schlessinger D, Wilhelm D, Koopman P, FOXL2 and BMP2 act cooperatively to regulate follistatin gene expression during ovarian development. Endocrinology. 2011 Jan;152(1):272-80 |
1 | J:69382 Lamm ML, Podlasek CA, Barnett DH, Lee J, Clemens JQ, Hebner CM, Bushman W, Mesenchymal factor bone morphogenetic protein 4 restricts ductal budding and branching morphogenesis in the developing prostate. Dev Biol. 2001 Apr 15;232(2):301-14 |
1 | J:168033 Li L, Lin M, Wang Y, Cserjesi P, Chen Z, Chen Y, BmprIa is required in mesenchymal tissue and has limited redundant function with BmprIb in tooth and palate development. Dev Biol. 2011 Jan 15;349(2):451-61 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
Bmpr1b bone morphogenetic protein receptor, type 1B (Synonyms: Acvrlk6, Alk6, BMPR-IB, CFK-43a) | |
Results | Reference |
1 | J:282102 Canizares MA, Albors AR, Singer G, Suttie N, Gorkic M, Felts P, Storey KG, Multiple steps characterise ventricular layer attrition to form the ependymal cell lining of the adult mouse spinal cord central canal. J Anat. 2019 Oct 31; |
1 | J:164103 Du Y, Xiao Q, Yip HK, Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the smad/id cascade. Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3764-73 |
1 | J:104840 Grishina IB, Kim SY, Ferrara C, Makarenkova HP, Walden PD, BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling. Dev Biol. 2005 Dec 15;288(2):334-47 |
1 | J:69382 Lamm ML, Podlasek CA, Barnett DH, Lee J, Clemens JQ, Hebner CM, Bushman W, Mesenchymal factor bone morphogenetic protein 4 restricts ductal budding and branching morphogenesis in the developing prostate. Dev Biol. 2001 Apr 15;232(2):301-14 |
1 | J:168033 Li L, Lin M, Wang Y, Cserjesi P, Chen Z, Chen Y, BmprIa is required in mesenchymal tissue and has limited redundant function with BmprIb in tooth and palate development. Dev Biol. 2011 Jan 15;349(2):451-61 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
Bmpr2 bone morphogenetic protein receptor type 2 (Synonyms: 2610024H22Rik, BMP-2, BMPR-II, BMPRII) | |
Results | Reference |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1* | J:168597 Kashimada K, Pelosi E, Chen H, Schlessinger D, Wilhelm D, Koopman P, FOXL2 and BMP2 act cooperatively to regulate follistatin gene expression during ovarian development. Endocrinology. 2011 Jan;152(1):272-80 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:42540 Roelen BA, Goumans MJ, van Rooijen MA, Mummery CL, Differential expression of BMP receptors in early mouse development. Int J Dev Biol. 1997 Aug;41(4):541-9 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
1* | J:332879 Zheng J, Liu H, Yu M, Lin B, Sun K, Liu H, Feng H, Liu Y, Han D, BMPR2 Variants Underlie Nonsyndromic Oligodontia. Int J Mol Sci. 2023 Jan 13;24(2) |
Bmx BMX non-receptor tyrosine kinase (Synonyms: Etk, Etk/Bmx, Tyro8) | |
Results | Reference |
1* | J:44871 Ekman N, Lymboussaki A, Vastrik I, Sarvas K, Kaipainen A, Alitalo K, Bmx tyrosine kinase is specifically expressed in the endocardium and the endothelium of large arteries. Circulation. 1997 Sep 16;96(6):1729-32 |
Bnc1 basonuclin zinc finger protein 1 | |
Results | Reference |
1* | J:231834 Vanhoutteghem A, Delhomme B, Herve F, Nondier I, Petit JM, Araki M, Araki K, Djian P, The importance of basonuclin 2 in adult mice and its relation to basonuclin 1. Mech Dev. 2016 May;140:53-73 |
1* | J:51091 Weiner L, Green H, Basonuclin as a cell marker in the formation and cycling of the murine hair follicle. Differentiation. 1998 Sep;63(5):263-72 |
Bnc2 basonuclin zinc finger protein 2 (Synonyms: 5031434M05Rik, 8430420F16Rik) | |
Results | Reference |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
2* | J:231834 Vanhoutteghem A, Delhomme B, Herve F, Nondier I, Petit JM, Araki M, Araki K, Djian P, The importance of basonuclin 2 in adult mice and its relation to basonuclin 1. Mech Dev. 2016 May;140:53-73 |
1* | J:151992 Vanhoutteghem A, Maciejewski-Duval A, Bouche C, Delhomme B, Herve F, Daubigney F, Soubigou G, Araki M, Araki K, Yamamura K, Djian P, Basonuclin 2 has a function in the multiplication of embryonic craniofacial mesenchymal cells and is orthologous to disco proteins. Proc Natl Acad Sci U S A. 2009 Aug 25;106(34):14432-7 |
Bnip3 BCL2/adenovirus E1B interacting protein 3 (Synonyms: Nip3) | |
Results | Reference |
1* | J:356303 Zhao Y, Zheng D, Cvekl A, A comprehensive spatial-temporal transcriptomic analysis of differentiating nascent mouse lens epithelial and fiber cells. Exp Eye Res. 2018 Oct;175:56-72 |
Bnip3l BCL2/adenovirus E1B interacting protein 3-like (Synonyms: D14Ertd719e, Nip3L, Nix) | |
Results | Reference |
1 | J:356661 Esteban-Martinez L, Sierra-Filardi E, McGreal RS, Salazar-Roa M, Marino G, Seco E, Durand S, Enot D, Grana O, Malumbres M, Cvekl A, Cuervo AM, Kroemer G, Boya P, Programmed mitophagy is essential for the glycolytic switch during cell differentiation. EMBO J. 2017 Jun 14;36(12):1688-1706 |
Boc BOC cell adhesion associated, oncogene regulated | |
Results | Reference |
2 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1* | J:75310 Mulieri PJ, Kang JS, Sassoon DA, Krauss RS, Expression of the boc gene during murine embryogenesis. Dev Dyn. 2002 Mar;223(3):379-88 |
2 | J:198426 Sanchez-Arrones L, Nieto-Lopez F, Sanchez-Camacho C, Carreres MI, Herrera E, Okada A, Bovolenta P, Shh/Boc signaling is required for sustained generation of ipsilateral projecting ganglion cells in the mouse retina. J Neurosci. 2013 May 15;33(20):8596-607 |
Bpifa1 BPI fold containing family A, member 1 (Synonyms: Plunc, SPLUNC1) | |
Results | Reference |
2 | J:70027 LeClair EE, Nguyen L, Bingle L, MacGowan A, Singleton V, Ward SJ, Bingle CD, Genomic organization of the mouse plunc gene and expression in the developing airways and thymus. Biochem Biophys Res Commun. 2001 Jun 15;284(3):792-7 |
Bpifa2 BPI fold containing family A, member 2 (Synonyms: Bpifa2e, Psp) | |
Results | Reference |
1 | J:341713 Aure MH, Symonds JM, Villapudua CU, Dodge JT, Werner S, Knosp WM, Hoffman MP, FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation. Nat Commun. 2023 Oct 14;14(1):6485 |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
Bpifb1 BPI fold containing family B, member 1 (Synonyms: 2310039C12Rik, LPlunc1, U46068, von Ebner minor salivary protein) | |
Results | Reference |
1* | J:88670 Hou J, Yashiro K, Okazaki Y, Saijoh Y, Hayashizaki Y, Hamada H, Identification of a novel left-right asymmetrically expressed gene in the mouse belonging to the BPI/PLUNC superfamily. Dev Dyn. 2004 Mar;229(2):373-9 |
Bptf bromodomain PHD finger transcription factor (Synonyms: 9430093H17Rik, Falz, MGC:54978) | |
Results | Reference |
1 | J:147414 Landry J, Sharov AA, Piao Y, Sharova LV, Xiao H, Southon E, Matta J, Tessarollo L, Zhang YE, Ko MS, Kuehn MR, Yamaguchi TP, Wu C, Essential role of chromatin remodeling protein Bptf in early mouse embryos and embryonic stem cells. PLoS Genet. 2008 Oct;4(10):e1000241 |
Braf Braf transforming gene (Synonyms: 9930012E13Rik, Braf-2, Braf2, D6Ertd631e) | |
Results | Reference |
1 | J:112971 Camarero G, Tyrsin OY, Xiang C, Pfeiffer V, Pleiser S, Wiese S, Gotz R, Rapp UR, Cortical migration defects in mice expressing A-RAF from the B-RAF locus. Mol Cell Biol. 2006 Oct;26(19):7103-15 |
1 | J:216228 Inoue S, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y, New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet. 2014 Dec 15;23(24):6553-66 |
1 | J:128917 Provot S, Nachtrab G, Paruch J, Chen AP, Silva A, Kronenberg HM, A-raf and B-raf are dispensable for normal endochondral bone development, and parathyroid hormone-related peptide suppresses extracellular signal-regulated kinase activation in hypertrophic chondrocytes. Mol Cell Biol. 2008 Jan;28(1):344-57 |
Brca1 breast cancer 1, early onset | |
Results | Reference |
1 | J:153169 Kouznetsova A, Wang H, Bellani M, Camerini-Otero RD, Jessberger R, Hoog C, BRCA1-mediated chromatin silencing is limited to oocytes with a small number of asynapsed chromosomes. J Cell Sci. 2009 Jul 15;122(Pt 14):2446-52 |
1 | J:29684 Lane TF, Deng C, Elson A, Lyu MS, Kozak CA, Leder P, Expression of Brca1 is associated with terminal differentiation of ectodermally and mesodermally derived tissues in mice. Genes Dev. 1995 Nov 1;9(21):2712-22 |
Brd2 bromodomain containing 2 (Synonyms: D17H6S113E, Frg-1, Fsrg1, Ring3, Rnf3) | |
Results | Reference |
1 | J:51809 Rhee K, Brunori M, Besset V, Trousdale R, Wolgemuth DJ, Expression and potential role of Fsrg1, a murine bromodomain-containing homologue of the Drosophila gene female sterile homeotic. J Cell Sci. 1998 Dec;111(Pt 23):3541-50 |
Brd7 bromodomain containing 7 (Synonyms: BP75, bromodomain protein 75 kDa, CELTIX1) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
Brpf3 bromodomain and PHD finger containing, 3 (Synonyms: MGC:58603, mKIAA1286) | |
Results | Reference |
1* | J:231042 Yan K, You L, Degerny C, Ghorbani M, Liu X, Chen L, Li L, Miao D, Yang XJ, The Chromatin Regulator BRPF3 Preferentially Activates the HBO1 Acetyltransferase but Is Dispensable for Mouse Development and Survival. J Biol Chem. 2016 Feb 5;291(6):2647-63 |
Brsk1 BR serine/threonine kinase 1 (Synonyms: LOC381979, SAD-B) | |
Results | Reference |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
Brsk2 BR serine/threonine kinase 2 (Synonyms: 4833424K13Rik, SAD-A) | |
Results | Reference |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
Brwd1 bromodomain and WD repeat domain containing 1 (Synonyms: 5330419I02Rik, D530019K20Rik, G1-403-16, repro5, Wdr9) | |
Results | Reference |
1* | J:84944 Huang H, Rambaldi I, Daniels E, Featherstone M, Expression of the Wdr9 gene and protein products during mouse development. Dev Dyn. 2003 Aug;227(4):608-14 |
Bscl2 BSCL2 lipid droplet biogenesis associated, seipin (Synonyms: Gng3lg, seipin) | |
Results | Reference |
1* | J:236180 Zhou H, Black SM, Benson TW, Weintraub NL, Chen W, Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is Not Required for Brown Adipogenesis but Regulates Brown Adipose Tissue Development and Function. Mol Cell Biol. 2016 Aug 1;36(15):2027-38 |
Bsg basigin (Synonyms: 5A11/Basigin, CD147, EMMPRIN, gp 42, HT-7, neurothelin) | |
Results | Reference |
2* | J:309605 Shi L, Li L, Wang D, Li S, Chen Z, An Z, Spatiotemporal expression of caveolin-1 and EMMPRIN during mouse tooth development. J Mol Histol. 2016 Jun;47(3):337-44 |
3* | J:173511 Xie M, Jiao T, Chen Y, Xu C, Li J, Jiang X, Zhang F, EMMPRIN (basigin/CD147) is involved in the morphogenesis of tooth germ in mouse molars. Histochem Cell Biol. 2010 May;133(5):585-94 |
Bsn bassoon (Synonyms: presynaptic cytomatrix protein) | |
Results | Reference |
1 | J:179778 Chen J, Mizushige T, Nishimune H, Active zone density is conserved during synaptic growth but impaired in aged mice. J Comp Neurol. 2012 Feb 1;520(2):434-52 |
Bsnd barttin CLCNK type accessory beta subunit (Synonyms: Bartter syndrome, infantile, with sensorineural deafness (Barttin)) | |
Results | Reference |
1 | J:249431 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ, Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6:e26851 |
Bsx brain specific homeobox (Synonyms: Bsx1a, Bsx1b) | |
Results | Reference |
1* | J:87378 Cremona M, Colombo E, Andreazzoli M, Cossu G, Broccoli V, Bsx, an evolutionary conserved Brain Specific homeoboX gene expressed in the septum, epiphysis, mammillary bodies and arcuate nucleus. Gene Expr Patterns. 2004 Jan;4(1):47-51 |
1 | J:263715 Lee B, Kim J, An T, Kim S, Patel EM, Raber J, Lee SK, Lee S, Lee JW, Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons. Nat Commun. 2018 May 23;9(1):2026 |
1 | J:237344 Lee B, Lee S, Lee SK, Lee JW, The LIM-homeobox transcription factor Isl1 plays crucial roles in the development of multiple arcuate nucleus neurons. Development. 2016 Oct 15;143(20):3763-3773 |
Btbd3 BTB domain containing 3 (Synonyms: MGC:25591, mKIAA0952) | |
Results | Reference |
1 | J:309347 Botella-Lopez A, Garcia-Lopez R, Pombero A, Martinez S, Radial glia fibers translate Fgf8 morphogenetic signals to generate a thalamic nuclear complex protomap in the mantle layer. Brain Struct Funct. 2019 Mar;224(2):661-679 |
Btbd7 BTB domain containing 7 (Synonyms: 5730507E09Rik, E130118E17Rik, FUP1, mKIAA1525) | |
Results | Reference |
1* | J:238590 Hayashi K, Ikari T, Sugiyama G, Sugiura T, Ohyama Y, Kumamaru W, Shirasuna K, Mori Y, Involvement of the T-box transcription factor Brachyury in early-stage embryonic mouse salivary gland. Biochem Biophys Res Commun. 2016 Sep 02;477(4):814-9 |
Btc betacellulin, epidermal growth factor family member | |
Results | Reference |
1* | J:130339 Minami S, Iwamoto R, Mekada E, HB-EGF decelerates cell proliferation synergistically with TGFalpha in perinatal distal lung development. Dev Dyn. 2008 Jan;237(1):247-58 |
Btg2 BTG anti-proliferation factor 2 (Synonyms: APRO1, Pc3, TIS21) | |
Results | Reference |
1 | J:144651 Farkas LM, Haffner C, Giger T, Khaitovich P, Nowick K, Birchmeier C, Paabo S, Huttner WB, Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex. Neuron. 2008 Oct 9;60(1):40-55 |
1 | J:211816 Fei JF, Haffner C, Huttner WB, 3' UTR-dependent, miR-92-mediated restriction of Tis21 expression maintains asymmetric neural stem cell division to ensure proper neocortex size. Cell Rep. 2014 Apr 24;7(2):398-411 |
1* | J:163966 Kowalczyk T, Pontious A, Englund C, Daza RA, Bedogni F, Hodge R, Attardo A, Bell C, Huttner WB, Hevner RF, Intermediate neuronal progenitors (basal progenitors) produce pyramidal-projection neurons for all layers of cerebral cortex. Cereb Cortex. 2009 Oct;19(10):2439-50 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1 | J:304969 Wu F, Bard JE, Kann J, Yergeau D, Sapkota D, Ge Y, Hu Z, Wang J, Liu T, Mu X, Single cell transcriptomics reveals lineage trajectory of retinal ganglion cells in wild-type and Atoh7-null retinas. Nat Commun. 2021 Mar 5;12(1):1465 |
Btg3 BTG anti-proliferation factor 3 (Synonyms: ANA, tob5) | |
Results | Reference |
1* | J:149251 Miyai K, Yoneda M, Hasegawa U, Toita S, Izu Y, Hemmi H, Hayata T, Ezura Y, Mizutani S, Miyazono K, Akiyoshi K, Yamamoto T, Noda M, ANA deficiency enhances bone morphogenetic protein-induced ectopic bone formation via transcriptional events. J Biol Chem. 2009 Apr 17;284(16):10593-600 |
Btg4 BTG anti-proliferation factor 4 (Synonyms: PC3B) | |
Results | Reference |
1* | J:64770 Buanne P, Corrente G, Micheli L, Palena A, Lavia P, Spadafora C, Lakshmana MK, Rinaldi A, Banfi S, Quarto M, Bulfone A, Tirone F, Cloning of PC3B, a novel member of the PC3/BTG/TOB family of growth inhibitory genes, highly expressed in the olfactory epithelium. Genomics. 2000 Sep 15;68(3):253-63 |
Btn1a1 butyrophilin, subfamily 1, member A1 (Synonyms: Btn) | |
Results | Reference |
1 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
Bub1 BUB1, mitotic checkpoint serine/threonine kinase (Synonyms: Bub1a, D2Xrf87) | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Bvht braveheart long non-coding RNA (Synonyms: Gm20748) | |
Results | Reference |
1* | J:283316 Garcia-Padilla C, Dominguez JN, Aranega AE, Franco D, Differential chamber-specific expression and regulation of long non-coding RNAs during cardiac development. Biochim Biophys Acta Gene Regul Mech. 2019 Oct;1862(10):194435 |
Bzw2 basic leucine zipper and W2 domains 2 (Synonyms: 1110001I24Rik, HSPC028, MGC:7203) | |
Results | Reference |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
C1qa complement component 1, q subcomponent, alpha polypeptide (Synonyms: C1q) | |
Results | Reference |
1 | J:326571 Mader S, Brimberg L, Vo A, Strohl JJ, Crawford JM, Bonnin A, Carrion J, Campbell D, Huerta TS, La Bella A, Berlin R, Dewey SL, Hellman M, Eidelberg D, Dujmovic I, Drulovic J, Bennett JL, Volpe BT, Huerta PT, Diamond B, In utero exposure to maternal anti-aquaporin-4 antibodies alters brain vasculature and neural dynamics in male mouse offspring. Sci Transl Med. 2022 Apr 20;14(641):eabe9726 |
C1qb complement component 1, q subcomponent, beta polypeptide | |
Results | Reference |
1 | J:273194 Anderson SR, Zhang J, Steele MR, Romero CO, Kautzman AG, Schafer DP, Vetter ML, Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia. J Neurosci. 2019 Mar 13;39(11):2025-2040 |
C1ql1 complement component 1, q subcomponent-like 1 (Synonyms: C1qrf) | |
Results | Reference |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
C1qtnf3 C1q and tumor necrosis factor related protein 3 (Synonyms: 2310005P21Rik, Corcs, CORS-26, CTRP3) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
C2cd4a C2 calcium-dependent domain containing 4A (Synonyms: EG244911, Fam148a) | |
Results | Reference |
1* | J:235223 Omori H, Ogaki S, Sakano D, Sato M, Umeda K, Takeda N, Nakagata N, Kume S, Changes in expression of C2cd4c in pancreatic endocrine cells during pancreatic development. FEBS Lett. 2016 Aug;590(16):2584-93 |
C2cd4b C2 calcium-dependent domain containing 4B (Synonyms: 3300001A09Rik, Fam148b) | |
Results | Reference |
1* | J:235223 Omori H, Ogaki S, Sakano D, Sato M, Umeda K, Takeda N, Nakagata N, Kume S, Changes in expression of C2cd4c in pancreatic endocrine cells during pancreatic development. FEBS Lett. 2016 Aug;590(16):2584-93 |
C2cd4c C2 calcium-dependent domain containing 4C (Synonyms: 4932409I22Rik, Fam148c, LOC237397) | |
Results | Reference |
1* | J:235223 Omori H, Ogaki S, Sakano D, Sato M, Umeda K, Takeda N, Nakagata N, Kume S, Changes in expression of C2cd4c in pancreatic endocrine cells during pancreatic development. FEBS Lett. 2016 Aug;590(16):2584-93 |
C2cd4d C2 calcium-dependent domain containing 4D (Synonyms: Gm659, LOC271944) | |
Results | Reference |
1* | J:235223 Omori H, Ogaki S, Sakano D, Sato M, Umeda K, Takeda N, Nakagata N, Kume S, Changes in expression of C2cd4c in pancreatic endocrine cells during pancreatic development. FEBS Lett. 2016 Aug;590(16):2584-93 |
C3 complement component 3 (Synonyms: acylation stimulating protein, complement factor 3, Plp) | |
Results | Reference |
3* | J:91319 Matthews KW, Drouin SM, Liu C, Martin JF, Skidgel RA, Wetsel RA, Expression of the third complement component (C3) and carboxypeptidase N small subunit (CPN1) during mouse embryonic development. Dev Comp Immunol. 2004 May 17;28(6):647-55 |
C3ar1 complement component 3a receptor 1 (Synonyms: anaphylatoxin C3a receptor, C3aR) | |
Results | Reference |
1 | J:320852 Coulthard LG, Hawksworth OA, Conroy J, Lee JD, Woodruff TM, Complement C3a receptor modulates embryonic neural progenitor cell proliferation and cognitive performance. Mol Immunol. 2018 Sep;101:176-181 |
C5ar1 complement component 5a receptor 1 (Synonyms: C5aR, C5r1, Cd88, D7Msu1) | |
Results | Reference |
2* | J:242692 Coulthard LG, Hawksworth OA, Li R, Balachandran A, Lee JD, Sepehrband F, Kurniawan N, Jeanes A, Simmons DG, Wolvetang E, Woodruff TM, Complement C5aR1 Signaling Promotes Polarization and Proliferation of Embryonic Neural Progenitor Cells through PKCzeta. J Neurosci. 2017 May 31;37(22):5395-5407 |
C9orf72 C9orf72, member of C9orf72-SMCR8 complex (Synonyms: 3110043O21Rik, Dennd9) | |
Results | Reference |
2 | J:250440 Ferguson R, Serafeimidou-Pouliou E, Subramanian V, Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation. J Anat. 2016 Dec;229(6):871-891 |
C030037D09Rik RIKEN cDNA C030037D09 gene | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
C730049O14Rik RIKEN cDNA C730049O14 gene | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
C920021L13Rik RIKEN cDNA C920021L13 gene (Synonyms: 100042889) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Cab39 calcium binding protein 39 (Synonyms: 39kDa, MO25alpha) | |
Results | Reference |
1 | J:207603 Veleva-Rotse BO, Smart JL, Baas AF, Edmonds B, Zhao ZM, Brown A, Klug LR, Hansen K, Reilly G, Gardner AP, Subbiah K, Gaucher EA, Clevers H, Barnes AP, STRAD pseudokinases regulate axogenesis and LKB1 stability. Neural Dev. 2014;9:5 |
Cabin1 calcineurin binding protein 1 (Synonyms: A330070M20Rik, Cain, Ppp3in) | |
Results | Reference |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Cachd1 cache domain containing 1 (Synonyms: 1190007F10Rik, B430218L07Rik, Vwcd1) | |
Results | Reference |
1* | J:314293 Tian C, Johnson KR, Lett JM, Voss R, Salt AN, Hartsock JJ, Steyger PS, Ohlemiller KK, CACHD1-deficient mice exhibit hearing and balance deficits associated with a disruption of calcium homeostasis in the inner ear. Hear Res. 2021 Sep 15;409:108327 |
Cacna1a calcium channel, voltage-dependent, P/Q type, alpha 1A subunit (Synonyms: alpha1A, Cacnl1a4, Ccha1a, nmf352, SCA6, smrl) | |
Results | Reference |
1* | J:38910 Doyle J, Ren X, Lennon G, Stubbs L, Mutations in the Cacnl1a4 calcium channel gene are associated with seizures, cerebellar degeneration, and ataxia in tottering and leaner mutant mice. Mamm Genome. 1997 Feb;8(2):113-20 |
Cacna1b calcium channel, voltage-dependent, N type, alpha 1B subunit (Synonyms: alpha(1B), Cav2.2, Cchn1a) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
Cacna1c calcium channel, voltage-dependent, L type, alpha 1C subunit (Synonyms: (alpha)1 subunit, Cav1.2, Cchl1a1, D930026N18Rik, L-type Cav1.2) | |
Results | Reference |
1* | J:90043 Acosta L, Haase H, Morano I, Moorman AF, Franco D, Regional expression of L-type calcium channel subunits during cardiac development. Dev Dyn. 2004 May;230(1):131-6 |
1 | J:228865 Law C, Schaan Profes M, Levesque M, Kaltschmidt JA, Verhage M, Kania A, Normal Molecular Specification and Neurodegenerative Disease-Like Death of Spinal Neurons Lacking the SNARE-Associated Synaptic Protein Munc18-1. J Neurosci. 2016 Jan 13;36(2):561-76 |
1 | J:320532 Lee SM, Yeh PWL, Yeh HH, L-Type Calcium Channels Contribute to Ethanol-Induced Aberrant Tangential Migration of Primordial Cortical GABAergic Interneurons in the Embryonic Medial Prefrontal Cortex. eNeuro. 2022 Jan-Feb;9(1):ENEURO.0359-21.2021 |
1 | J:341710 Li H, Korcari A, Ciufo D, Mendias CL, Rodeo SA, Buckley MR, Loiselle AE, Pitt GS, Cao C, Increased Ca(2+) signaling through Ca(V) 1.2 induces tendon hypertrophy with increased collagen fibrillogenesis and biomechanical properties. FASEB J. 2023 Jul;37(7):e23007 |
1* | J:100234 Shao Y, Alicknavitch M, Farach-Carson MC, Expression of voltage sensitive calcium channel (VSCC) L-type Cav1.2 (alpha1C) and T-type Cav3.2 (alpha1H) subunits during mouse bone development. Dev Dyn. 2005 Sep;234(1):54-62 |
Cacna1d calcium channel, voltage-dependent, L type, alpha 1D subunit (Synonyms: 8430418G19Rik, C79217, Cacnl1a2, Cav1.3alpha1, Cchl1a, Cchl1a2, D-LTCC) | |
Results | Reference |
1* | J:164341 Kersten FF, van Wijk E, van Reeuwijk J, van der Zwaag B, Marker T, Peters TA, Katsanis N, Wolfrum U, Keunen JE, Roepman R, Kremer H, Association of whirlin with Cav1.3 (alpha1D) channels in photoreceptors, defining a novel member of the usher protein network. Invest Ophthalmol Vis Sci. 2010 May;51(5):2338-46 |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1* | J:281311 Nakano Y, Wiechert S, Banfi B, Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8 |
1 | J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12) |
Cacna1g calcium channel, voltage-dependent, T type, alpha 1G subunit (Synonyms: a1G, Cav3.1d, mKIAA1123) | |
Results | Reference |
1* | J:79637 Berthier C, Monteil A, Lory P, Strube C, Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice. J Physiol. 2002 Mar 15;539(Pt 3):681-91 |
Cacna1h calcium channel, voltage-dependent, T type, alpha 1H subunit (Synonyms: alpha13.2, Cav3.2, mKIAA1120, T-type Cav3.2) | |
Results | Reference |
1 | J:309445 Bernal Sierra YA, Haseleu J, Kozlenkov A, Begay V, Lewin GR, Genetic Tracing of Cav3.2 T-Type Calcium Channel Expression in the Peripheral Nervous System. Front Mol Neurosci. 2017;10:70 |
1* | J:79637 Berthier C, Monteil A, Lory P, Strube C, Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice. J Physiol. 2002 Mar 15;539(Pt 3):681-91 |
1* | J:100234 Shao Y, Alicknavitch M, Farach-Carson MC, Expression of voltage sensitive calcium channel (VSCC) L-type Cav1.2 (alpha1C) and T-type Cav3.2 (alpha1H) subunits during mouse bone development. Dev Dyn. 2005 Sep;234(1):54-62 |
Cacna1i calcium channel, voltage-dependent, alpha 1I subunit | |
Results | Reference |
1* | J:79637 Berthier C, Monteil A, Lory P, Strube C, Alpha(1H) mRNA in single skeletal muscle fibres accounts for T-type calcium current transient expression during fetal development in mice. J Physiol. 2002 Mar 15;539(Pt 3):681-91 |
Cacna1s calcium channel, voltage-dependent, L type, alpha 1S subunit (Synonyms: Cav1.1, Cchl1a3, DHPR alpha1s, fmd, mdg, muscle dysgenesis, sj) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Cacna2d1 calcium channel, voltage-dependent, alpha2/delta subunit 1 (Synonyms: Cacna2, Ca(v)alpha2delta1, Cchl2a) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1* | J:243480 Gomez-Herreros F, Schuurs-Hoeijmakers JH, McCormack M, Greally MT, Rulten S, Romero-Granados R, Counihan TJ, Chaila E, Conroy J, Ennis S, Delanty N, Cortes-Ledesma F, de Brouwer AP, Cavalleri GL, El-Khamisy SF, de Vries BB, Caldecott KW, TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function. Nat Genet. 2014 May;46(5):516-21 |
1* | J:114661 Lyu YL, Lin CP, Azarova AM, Cai L, Wang JC, Liu LF, Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Mol Cell Biol. 2006 Nov;26(21):7929-41 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Cacna2d3 calcium channel, voltage-dependent, alpha2/delta subunit 3 (Synonyms: alpha 2 delta-3, alpha2delta3) | |
Results | Reference |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
Cacnb1 calcium channel, voltage-dependent, beta 1 subunit (Synonyms: Cchb1, Cchlb1) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Cacnb2 calcium channel, voltage-dependent, beta 2 subunit (Synonyms: Cavbeta2, Cchb2) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Cacnb3 calcium channel, voltage-dependent, beta 3 subunit (Synonyms: Beta3, Cchb3) | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Cadm1 cell adhesion molecule 1 (Synonyms: 2900073G06Rik, 3100001I08Rik, Igsf4, Igsf4a, Necl2, RA175A, RA175B, RA175C, RA175N, SgIGSF, SynCam, Tslc1) | |
Results | Reference |
1 | J:126582 Cobos I, Borello U, Rubenstein JL, Dlx transcription factors promote migration through repression of axon and dendrite growth. Neuron. 2007 Jun 21;54(6):873-88 |
2 | J:96462 Fujita E, Urase K, Soyama A, Kouroku Y, Momoi T, Distribution of RA175/TSLC1/SynCAM, a member of the immunoglobulin superfamily, in the developing nervous system. Brain Res Dev Brain Res. 2005 Feb 8;154(2):199-209 |
1 | J:192461 Inoue T, Hagiyama M, Enoki E, Sakurai MA, Tan A, Wakayama T, Iseki S, Murakami Y, Fukuda K, Hamanishi C, Ito A, Cell adhesion molecule 1 is a new osteoblastic cell adhesion molecule and a diagnostic marker for osteosarcoma. Life Sci. 2013 Jan 17;92(1):91-9 |
1 | J:120218 Ito A, Nishikawa Y, Ohnuma K, Ohnuma I, Koma Y, Sato A, Enomoto K, Tsujimura T, Yokozaki H, SgIGSF is a novel biliary-epithelial cell adhesion molecule mediating duct/ductule development. Hepatology. 2007 Mar;45(3):684-94 |
2* | J:98297 Ohta Y, Itoh K, Yaoi T, Tando S, Fukui K, Fushiki S, Spatiotemporal patterns of expression of IGSF4 in developing mouse nervous system. Brain Res Dev Brain Res. 2005 Apr 21;156(1):23-31 |
1* | J:74191 Urase K, Soyama A, Fujita E, Momoi T, Expression of RA175 mRNA, a new member of the immunoglobulin superfamily, in developing mouse brain. Neuroreport. 2001 Oct 29;12(15):3217-21 |
Cadm3 cell adhesion molecule 3 (Synonyms: BIgR, Igsf4b, Necl-1, Necl1, SynCAM3, Tsll1) | |
Results | Reference |
1* | J:142504 Park J, Liu B, Chen T, Li H, Hu X, Gao J, Zhu Y, Zhu Q, Qiang B, Yuan J, Peng X, Qiu M, Disruption of Nectin-like 1 cell adhesion molecule leads to delayed axonal myelination in the CNS. J Neurosci. 2008 Nov 26;28(48):12815-9 |
Cadps Ca2+-dependent secretion activator (Synonyms: CAPS1, mKIAA1121) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Calb1 calbindin 1 (Synonyms: Brain-2, Calb, Calb-1, calbindin, calbindin-D (28k), CalbindinD28K, CB) | |
Results | Reference |
1 | J:50421 Alcantara S, Ruiz M, D'Arcangelo G, Ezan F, de Lecea L, Curran T , Sotelo C , Soriano E, Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse. J Neurosci. 1998 Oct 1;18(19):7779-99 |
1 | J:195145 Amaniti EM, Hasenpusch-Theil K, Li Z, Magnani D, Kessaris N, Mason JO, Theil T, Gli3 is required in Emx1(+) progenitors for the development of the corpus callosum. Dev Biol. 2013 Apr 15;376(2):113-24 |
1 | J:273194 Anderson SR, Zhang J, Steele MR, Romero CO, Kautzman AG, Schafer DP, Vetter ML, Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia. J Neurosci. 2019 Mar 13;39(11):2025-2040 |
1 | J:181188 Aoki H, Hara A, Era T, Kunisada T, Yamada Y, Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development. 2012 Feb;139(4):667-77 |
1 | J:225279 Arno B, Grassivaro F, Rossi C, Bergamaschi A, Castiglioni V, Furlan R, Greter M, Favaro R, Comi G, Becher B, Martino G, Muzio L, Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex. Nat Commun. 2014;5:5611 |
1 | J:98945 Ballas N, Grunseich C, Lu DD, Speh JC, Mandel G, REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell. 2005 May 20;121(4):645-57 |
1* | J:142365 Barry G, Piper M, Lindwall C, Moldrich R, Mason S, Little E, Sarkar A, Tole S, Gronostajski RM, Richards LJ, Specific glial populations regulate hippocampal morphogenesis. J Neurosci. 2008 Nov 19;28(47):12328-40 |
1 | J:183848 Benadiba C, Magnani D, Niquille M, Morle L, Valloton D, Nawabi H, Ait-Lounis A, Otsmane B, Reith W, Theil T, Hornung JP, Lebrand C, Durand B, The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development. PLoS Genet. 2012 Mar;8(3):e1002606 |
1 | J:148805 Buckiova D, Syka J, Calbindin and S100 protein expression in the developing inner ear in mice. J Comp Neurol. 2009 Apr 10;513(5):469-82 |
1 | J:93825 Cebrian C, Borodo K, Charles N, Herzlinger DA, Morphometric index of the developing murine kidney. Dev Dyn. 2004 Nov;231(3):601-8 |
1 | J:70560 Chen Z, Rebelo S, White F, Malmberg AB, Baba H, Lima D, Woolf CJ, Basbaum AI, Anderson DJ, The paired homeodomain protein drg11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord. Neuron. 2001 Jul 19;31(1):59-73 |
1 | J:119033 Chizhikov VV, Lindgren AG, Currle DS, Rose MF, Monuki ES, Millen KJ, The roof plate regulates cerebellar cell-type specification and proliferation. Development. 2006 Aug;133(15):2793-804 |
1 | J:237525 Chung E, Deacon P, Marable S, Shin J, Park JS, Notch signaling promotes nephrogenesis by downregulating Six2. Development. 2016 Nov 01;143(21):3907-3913 |
1* | J:98171 Cobos I, Broccoli V, Rubenstein JL, The vertebrate ortholog of Aristaless is regulated by Dlx genes in the developing forebrain. J Comp Neurol. 2005 Mar 14;483(3):292-303 |
1 | J:94263 Davila JC, Real MA, Olmos L, Legaz I, Medina L, Guirado S, Embryonic and postnatal development of GABA, calbindin, calretinin, and parvalbumin in the mouse claustral complex. J Comp Neurol. 2005 Jan 3;481(1):42-57 |
1* | J:74080 Del Rio JA, Martinez A, Auladell C, Soriano E, Developmental history of the subplate and developing white matter in the murine neocortex. Neuronal organization and relationship with the main afferent systems at embryonic and perinatal stages. Cereb Cortex. 2000 Aug;10(8):784-801 |
1 | J:176438 Esteve P, Sandonis A, Ibanez C, Shimono A, Guerrero I, Bovolenta P, Secreted frizzled-related proteins are required for Wnt/{beta}-catenin signalling activation in the vertebrate optic cup. Development. 2011 Oct;138(19):4179-84 |
1 | J:163224 Garcia-Lopez M, Abellan A, Legaz I, Rubenstein JL, Puelles L, Medina L, Histogenetic compartments of the mouse centromedial and extended amygdala based on gene expression patterns during development. J Comp Neurol. 2008 Jan 1;506(1):46-74 |
1 | J:153202 Gerber SD, Steinberg F, Beyeler M, Villiger PM, Trueb B, The murine Fgfrl1 receptor is essential for the development of the metanephric kidney. Dev Biol. 2009 Nov 1;335(1):106-19 |
1 | J:174117 Gopal PP, Golden JA, Pax6-/- mice have a cell nonautonomous defect in nonradial interneuron migration. Cereb Cortex. 2008 Apr;18(4):752-62 |
1 | J:101176 Grieshammer U, Cebrian C, Ilagan R, Meyers E, Herzlinger D, Martin GR, FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons. Development. 2005 Sep;132(17):3847-57 |
1 | J:202183 Hao MM, Bornstein JC, Young HM, Development of myenteric cholinergic neurons in ChAT-Cre;R26R-YFP mice. J Comp Neurol. 2013 Oct 1;521(14):3358-70 |
1 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:82656 Hevner RF, Neogi T, Englund C, Daza RA, Fink A, Cajal-Retzius cells in the mouse: transcription factors, neurotransmitters, and birthdays suggest a pallial origin. Brain Res Dev Brain Res. 2003 Mar 14;141(1-2):39-53 |
1 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1 | J:130251 Hori K, Cholewa-Waclaw J, Nakada Y, Glasgow SM, Masui T, Henke RM, Wildner H, Martarelli B, Beres TM, Epstein JA, Magnuson MA, Macdonald RJ, Birchmeier C, Johnson JE, A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes Dev. 2008 Jan 15;22(2):166-78 |
1 | J:100997 Hoshino M, Nakamura S, Mori K, Kawauchi T, Terao M, Nishimura YV, Fukuda A, Fuse T, Matsuo N, Sone M, Watanabe M, Bito H, Terashima T, Wright CV, Kawaguchi Y, Nakao K, Nabeshima Y, Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum. Neuron. 2005 Jul 21;47(2):201-13 |
1* | J:150882 Ichikawa H, Terayama R, Yamaai T, Jacobowitz DM, Qiu F, Xiang M, Sugimoto T, Brn-3a deficiency transiently increases expression of calbindin D-28 k and calretinin in the trigeminal ganglion during embryonic development. Cell Mol Neurobiol. 2009 Jul;29(5):691-8 |
1 | J:65749 Jimenez D, Garcia C, de Castro F, Chedotal A, Sotelo C, de Carlos JA, Valverde F, Lopez-Mascaraque L, Evidence for intrinsic development of olfactory structures in Pax-6 mutant mice. J Comp Neurol. 2000 Dec 18;428(3):511-26 |
1 | J:85869 Jimenez D, Lopez-Mascaraque L, De Carlos JA, Valverde F, Further studies on cortical tangential migration in wild type and Pax-6 mutant mice. J Neurocytol. 2002 Sep-Oct;31(8-9):719-28 |
1 | J:168981 Kim JJ, Gill PS, Rotin L, van Eede M, Henkelman RM, Hui CC, Rosenblum ND, Suppressor of Fused Controls Mid-Hindbrain Patterning and Cerebellar Morphogenesis via GLI3 Repressor. J Neurosci. 2011 Feb 2;31(5):1825-36 |
1 | J:88219 King JS, Bishop GA, Localization of the type 1 corticotropin releasing factor receptor (CRF-R1) in the embryonic mouse cerebellum. J Neurocytol. 2003 Mar;32(3):305-16 |
1* | J:79871 Kitamura K, Yanazawa M, Sugiyama N, Miura H, Iizuka-Kogo A, Kusaka M, Omichi K, Suzuki R, Kato-Fukui Y, Kamiirisa K, Matsuo M, Kamijo S, Kasahara M, Yoshioka H, Ogata T, Fukuda T, Kondo I, Kato M, Dobyns WB, Yokoyama M, Morohashi K, Mutation of ARX causes abnormal development of forebrain and testes in mice and X-linked lissencephaly with abnormal genitalia in humans. Nat Genet. 2002 Nov;32(3):359-69 |
1 | J:333405 Kurtzeborn K, Kwon HN, Iaroshenko V, Faisal I, Ambroz M, Jin X, Qureshi T, Kupari J, Ihermann-Hella A, Vaananen J, Tyynismaa H, Bousova I, Park S, Kuure S, Comparative whole-genome transcriptome analysis in renal cell populations reveals high tissue specificity of MAPK/ERK targets in embryonic kidney. BMC Biol. 2022 May 13;20(1):112 |
1 | J:225435 Laclef C, Anselme I, Besse L, Catala M, Palmyre A, Baas D, Paschaki M, Pedraza M, Metin C, Durand B, Schneider-Maunoury S, The role of primary cilia in corpus callosum formation is mediated by production of the Gli3 repressor. Hum Mol Genet. 2015 Sep 1;24(17):4997-5014 |
1 | J:99635 Legaz I, Olmos L, Real MA, Guirado S, Davila JC, Medina L, Development of neurons and fibers containing calcium binding proteins in the pallial amygdala of mouse, with special emphasis on those of the basolateral amygdalar complex. J Comp Neurol. 2005 Aug 8;488(4):492-513 |
1 | J:325446 Lepiemme F, Stoufflet J, Javier-Torrent M, Mazzucchelli G, Silva CG, Nguyen L, Oligodendrocyte precursors guide interneuron migration by unidirectional contact repulsion. Science. 2022 May 20;376(6595):eabn6204 |
1 | J:21296 Liu L, Dunn ST, Christakos S, Hanson-Painton O, Bourdeau JE, Calbindin-D28k gene expression in the developing mouse kidney. Kidney Int. 1993 Aug;44(2):322-30 |
1* | J:329558 Liu W, Chen H, Zhu X, Yu H, Expression of Calbindin-D28K in the Developing and Adult Mouse Cochlea. J Histochem Cytochem. 2022 Aug;70(8):583-596 |
1 | J:160654 Machold RP, Kittell DJ, Fishell GJ, Antagonism between Notch and bone morphogenetic protein receptor signaling regulates neurogenesis in the cerebellar rhombic lip. Neural Dev. 2007;2:5 |
1 | J:217046 Magnani D, Hasenpusch-Theil K, Benadiba C, Yu T, Basson MA, Price DJ, Lebrand C, Theil T, Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Cereb Cortex. 2014 Jan;24(1):186-98 |
1 | J:214970 Mecklenburg N, Martinez-Lopez JE, Moreno-Bravo JA, Perez-Balaguer A, Puelles E, Martinez S, Growth and differentiation factor 10 (Gdf10) is involved in Bergmann glial cell development under Shh regulation. Glia. 2014 Oct;62(10):1713-23 |
1 | J:186443 Muller Smith K, Williamson TL, Schwartz ML, Vaccarino FM, Impaired motor coordination and disrupted cerebellar architecture in Fgfr1 and Fgfr2 double knockout mice. Brain Res. 2012 Jun 15;1460:12-24 |
1 | J:17458 Ninomiya T, Vuillemin M, Walter-Barakat I, Winking H, Pexieder T, Droz B, Mouse fetal trisomy 13 and hypotrophy of the spinal cord: effect on calbindin-D28k and calretinin expressed by neurons of the spinal cord and dorsal root ganglia. Neuroscience. 1993 Dec;57(4):1109-20 |
1 | J:206963 Orieux G, Picault L, Slembrouck A, Roger JE, Guillonneau X, Sahel JA, Saule S, McPherson JP, Goureau O, Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells. J Neurosci. 2014 Jan 22;34(4):1530-41 |
1 | J:185279 Paces-Fessy M, Fabre M, Lesaulnier C, Cereghini S, Hnf1b and Pax2 cooperate to control different pathways in kidney and ureter morphogenesis. Hum Mol Genet. 2012 Jul 15;21(14):3143-55 |
1 | J:315120 Panman L, Papathanou M, Laguna A, Oosterveen T, Volakakis N, Acampora D, Kurtsdotter I, Yoshitake T, Kehr J, Joodmardi E, Muhr J, Simeone A, Ericson J, Perlmann T, Sox6 and Otx2 control the specification of substantia nigra and ventral tegmental area dopamine neurons. Cell Rep. 2014 Aug 21;8(4):1018-25 |
1 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:69135 Powell EM, Mars WM, Levitt P, Hepatocyte growth factor/scatter factor is a motogen for interneurons migrating from the ventral to dorsal telencephalon. Neuron. 2001 Apr;30(1):79-89 |
1 | J:192558 Rabe TI, Griesel G, Blanke S, Kispert A, Leitges M, van der Zwaag B, Burbach JP, Varoqueaux F, Mansouri A, The transcription factor Uncx4.1 acts in a short window of midbrain dopaminergic neuron differentiation. Neural Dev. 2012;7:39 |
1* | J:174050 Rakic S, Yanagawa Y, Obata K, Faux C, Parnavelas JG, Nikolic M, Cortical interneurons require p35/Cdk5 for their migration and laminar organization. Cereb Cortex. 2009 Aug;19(8):1857-69 |
1 | J:195266 Reginensi A, Scott RP, Gregorieff A, Bagherie-Lachidan M, Chung C, Lim DS, Pawson T, Wrana J, McNeill H, Yap- and Cdc42-Dependent Nephrogenesis and Morphogenesis during Mouse Kidney Development. PLoS Genet. 2013 Mar;9(3):e1003380 |
1 | J:108169 Ruan HZ, Moules E, Burnstock G, Changes in P2X3 purinoceptors in sensory ganglia of the mouse during embryonic and postnatal development. Histochem Cell Biol. 2004 Dec;122(6):539-51 |
1 | J:163753 Sessa A, Mao CA, Colasante G, Nini A, Klein WH, Broccoli V, Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of subpallial GABAergic interneurons. Genes Dev. 2010 Aug 15;24(16):1816-26 |
1 | J:178995 Stam FJ, Hendricks TJ, Zhang J, Geiman EJ, Francius C, Labosky PA, Clotman F, Goulding M, Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program. Development. 2012 Jan;139(1):179-90 |
1 | J:160871 Sudarov A, Joyner AL, Cerebellum morphogenesis: the foliation pattern is orchestrated by multi-cellular anchoring centers. Neural Dev. 2007;2:26 |
1* | J:134562 Trapp ML, Galtseva A, Manning DK, Beier DR, Rosenblum ND, Quarmby LM, Defects in ciliary localization of Nek8 is associated with cystogenesis. Pediatr Nephrol. 2008 Mar;23(3):377-87 |
1 | J:102950 Xu Q, Wonders CP, Anderson SA, Sonic hedgehog maintains the identity of cortical interneuron progenitors in the ventral telencephalon. Development. 2005 Nov;132(22):4987-98 |
1 | J:293780 Yamazaki Y, Nagai J, Akinaga S, Koga Y, Hasegawa M, Takahashi M, Yamashita N, Kolattukudy P, Goshima Y, Ohshima T, Phosphorylation of CRMP2 is required for migration and positioning of Purkinje cells: Redundant roles of CRMP1 and CRMP4. Brain Res. 2020 Jun 1;1736:146762 |
1 | J:317798 Yoo JY, Larouche M, Goldowitz D, The expression of HDAC1 and HDAC2 during cerebellar cortical development. Cerebellum. 2013 Aug;12(4):534-46 |
1* | J:16839 Yuasa S, Kitoh J, Oda S, Kawamura K, Obstructed migration of Purkinje cells in the developing cerebellum of the reeler mutant mouse. Anat Embryol (Berl). 1993 Oct;188(4):317-29 |
1 | J:108702 Zhang CL, Zou Y, Yu RT, Gage FH, Evans RM, Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes Dev. 2006 May 15;20(10):1308-20 |
1 | J:217063 Zou M, Luo H, Xiang M, Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord. Dev Dyn. 2015 Jan;244(1):86-97 |
Calb2 calbindin 2 (Synonyms: calretinin, CR) | |
Results | Reference |
1 | J:26659 Abbott LC, Jacobowitz DM, Development of calretinin-immunoreactive unipolar brush-like cells and an afferent pathway to the embryonic and early postnatal mouse cerebellum. Anat Embryol (Berl). 1995 Jun;191(6):541-59 |
1* | J:59626 Abbott LC, Jacobowitz DM, Developmental expression of calretinin-immunoreactivity in the thalamic eminence of the fetal mouse. Int J Dev Neurosci. 1999 Jul;17(4):331-45 |
1 | J:50421 Alcantara S, Ruiz M, D'Arcangelo G, Ezan F, de Lecea L, Curran T , Sotelo C , Soriano E, Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse. J Neurosci. 1998 Oct 1;18(19):7779-99 |
1 | J:195145 Amaniti EM, Hasenpusch-Theil K, Li Z, Magnani D, Kessaris N, Mason JO, Theil T, Gli3 is required in Emx1(+) progenitors for the development of the corpus callosum. Dev Biol. 2013 Apr 15;376(2):113-24 |
2 | J:291525 Amelio I, Panatta E, Niklison-Chirou MV, Steinert JR, Agostini M, Morone N, Knight RA, Melino G, The C terminus of p73 is essential for hippocampal development. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15694-15701 |
1* | J:142365 Barry G, Piper M, Lindwall C, Moldrich R, Mason S, Little E, Sarkar A, Tole S, Gronostajski RM, Richards LJ, Specific glial populations regulate hippocampal morphogenesis. J Neurosci. 2008 Nov 19;28(47):12328-40 |
1 | J:183848 Benadiba C, Magnani D, Niquille M, Morle L, Valloton D, Nawabi H, Ait-Lounis A, Otsmane B, Reith W, Theil T, Hornung JP, Lebrand C, Durand B, The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development. PLoS Genet. 2012 Mar;8(3):e1002606 |
1* | J:55694 Bermingham NA, Hassan BA, Price SD, Vollrath MA, Ben-Arie N, Eatock RA, Bellen HJ, Lysakowski A, Zoghbi HY, Math1: an essential gene for the generation of inner ear hair cells. Science. 1999 Jun 11;284(5421):1837-41 |
1* | J:316680 Blum W, Pecze L, Felley-Bosco E, Schwaller B, Overexpression or absence of calretinin in mouse primary mesothelial cells inversely affects proliferation and cell migration. Respir Res. 2015 Dec 22;16:153 |
1 | J:113151 Borrell V, Marin O, Meninges control tangential migration of hem-derived Cajal-Retzius cells via CXCL12/CXCR4 signaling. Nat Neurosci. 2006 Oct;9(10):1284-93 |
1* | J:149467 Bosman EA, Quint E, Fuchs H, Hrabe de Angelis M, Steel KP, Catweasel mice: a novel role for Six1 in sensory patch development and a model for branchio-oto-renal syndrome. Dev Biol. 2009 Apr 15;328(2):285-96 |
1 | J:184876 Chiara F, Badaloni A, Croci L, Yeh ML, Cariboni A, Hoerder-Suabedissen A, Consalez GG, Eickholt B, Shimogori T, Parnavelas JG, Rakic S, Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem. Dev Biol. 2012 May 1;365(1):277-89 |
1 | J:235552 Chinn GA, Hirokawa KE, Chuang TM, Urbina C, Patel F, Fong J, Funatsu N, Monuki ES, Agenesis of the Corpus Callosum Due to Defective Glial Wedge Formation in Lhx2 Mutant Mice. Cereb Cortex. 2015 Sep;25(9):2707-18 |
1 | J:175562 Cho IH, Lee KW, Ha HY, Han PL, JNK/stress-activated protein kinase associated protein 1 is required for early development of telencephalic commissures in embryonic brains. Exp Mol Med. 2011 Aug 31;43(8):462-70 |
1 | J:182705 Choe Y, Siegenthaler JA, Pleasure SJ, A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Neuron. 2012 Feb 23;73(4):698-712 |
1 | J:94263 Davila JC, Real MA, Olmos L, Legaz I, Medina L, Guirado S, Embryonic and postnatal development of GABA, calbindin, calretinin, and parvalbumin in the mouse claustral complex. J Comp Neurol. 2005 Jan 3;481(1):42-57 |
1 | J:19909 Dechesne CJ, Rabejac D, Desmadryl G, Development of calretinin immunoreactivity in the mouse inner ear. J Comp Neurol. 1994 Aug 22;346(4):517-29 |
1* | J:74080 Del Rio JA, Martinez A, Auladell C, Soriano E, Developmental history of the subplate and developing white matter in the murine neocortex. Neuronal organization and relationship with the main afferent systems at embryonic and perinatal stages. Cereb Cortex. 2000 Aug;10(8):784-801 |
1 | J:23064 del Rio JA, Martinez A, Fonseca M, Auladell C, Soriano E, Glutamate-like immunoreactivity and fate of Cajal-Retzius cells in the murine cortex as identified with calretinin antibody. Cereb Cortex. 1995 Jan-Feb;5(1):13-21 |
1 | J:99355 Depaepe V, Suarez-Gonzalez N, Dufour A, Passante L, Gorski JA, Jones KR, Ledent C, Vanderhaeghen P, Ephrin signalling controls brain size by regulating apoptosis of neural progenitors. Nature. 2005 Jun 30;435(7046):1244-50 |
1* | J:118243 Fan X, Warner M, Gustafsson JA, Estrogen receptor beta expression in the embryonic brain regulates development of calretinin-immunoreactive GABAergic interneurons. Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19338-43 |
1 | J:59284 Galceran J, Miyashita-Lin EM, Devaney E, Rubenstein JL, Grosschedl R, Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1. Development. 2000 Feb;127(3):469-82 |
1 | J:174117 Gopal PP, Golden JA, Pax6-/- mice have a cell nonautonomous defect in nonradial interneuron migration. Cereb Cortex. 2008 Apr;18(4):752-62 |
1 | J:229411 Hakanen J, Salminen M, Defects in neural guidepost structures and failure to remove leptomeningeal cells from the septal midline behind the interhemispheric fusion defects in Netrin1 deficient mice. Int J Dev Neurosci. 2015 Dec;47(Pt B):206-15 |
1 | J:82656 Hevner RF, Neogi T, Englund C, Daza RA, Fink A, Cajal-Retzius cells in the mouse: transcription factors, neurotransmitters, and birthdays suggest a pallial origin. Brain Res Dev Brain Res. 2003 Mar 14;141(1-2):39-53 |
1 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1* | J:150882 Ichikawa H, Terayama R, Yamaai T, Jacobowitz DM, Qiu F, Xiang M, Sugimoto T, Brn-3a deficiency transiently increases expression of calbindin D-28 k and calretinin in the trigeminal ganglion during embryonic development. Cell Mol Neurobiol. 2009 Jul;29(5):691-8 |
1 | J:134970 Inoue T, Ogawa M, Mikoshiba K, Aruga J, Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly. J Neurosci. 2008 Apr 30;28(18):4712-25 |
1 | J:65749 Jimenez D, Garcia C, de Castro F, Chedotal A, Sotelo C, de Carlos JA, Valverde F, Lopez-Mascaraque L, Evidence for intrinsic development of olfactory structures in Pax-6 mutant mice. J Comp Neurol. 2000 Dec 18;428(3):511-26 |
1 | J:99635 Legaz I, Olmos L, Real MA, Guirado S, Davila JC, Medina L, Development of neurons and fibers containing calcium binding proteins in the pallial amygdala of mouse, with special emphasis on those of the basolateral amygdalar complex. J Comp Neurol. 2005 Aug 8;488(4):492-513 |
1 | J:83383 Levi G, Puche AC, Mantero S, Barbieri O, Trombino S, Paleari L, Egeo A, Merlo GR, The Dlx5 homeodomain gene is essential for olfactory development and connectivity in the mouse. Mol Cell Neurosci. 2003 Apr;22(4):530-43 |
1 | J:136385 Li S, Jin Z, Koirala S, Bu L, Xu L, Hynes RO, Walsh CA, Corfas G, Piao X, GPR56 regulates pial basement membrane integrity and cortical lamination. J Neurosci. 2008 May 28;28(22):5817-26 |
1 | J:343468 Li Y, Xiao D, Chen H, Zheng XFS, Xiang M, Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms. iScience. 2023 Dec 15;26(12):108544 |
1 | J:309491 Liu J, Liu B, Zhang X, Yu B, Guan W, Wang K, Yang Y, Gong Y, Wu X, Yanagawa Y, Wu S, Zhao C, Calretinin-positive L5a pyramidal neurons in the development of the paralemniscal pathway in the barrel cortex. Mol Brain. 2014 Nov 18;7:84 |
1 | J:94879 Lyu YL, Wang JC, Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase IIbeta. Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7123-8 |
1 | J:217046 Magnani D, Hasenpusch-Theil K, Benadiba C, Yu T, Basson MA, Price DJ, Lebrand C, Theil T, Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Cereb Cortex. 2014 Jan;24(1):186-98 |
1 | J:338454 Marfull-Oromi P, Fleitas C, Zammou B, Rocandio D, Ballester-Lurbe B, Terrado J, Perez-Roger I, Espinet C, Egea J, Genetic ablation of the Rho GTPase Rnd3 triggers developmental defects in internal capsule and the globus pallidus formation. J Neurochem. 2021 Jul;158(2):197-216 |
1* | J:88779 Martin DM, Skidmore JM, Philips ST, Vieira C, Gage PJ, Condie BG, Raphael Y, Martinez S, Camper SA, PITX2 is required for normal development of neurons in the mouse subthalamic nucleus and midbrain. Dev Biol. 2004 Mar 1;267(1):93-108 |
1* | J:78406 Merlo GR, Paleari L, Mantero S, Zerega B, Adamska M, Rinkwitz S, Bober E, Levi G, The Dlx5 homeobox gene is essential for vestibular morphogenesis in the mouse embryo through a BMP4-mediated pathway. Dev Biol. 2002 Aug 1;248(1):157-69 |
1 | J:91334 Mhatre AN, Li J, Kim Y, Coling DE, Lalwani AK, Cloning and developmental expression of nonmuscle myosin IIA (Myh9) in the mammalian inner ear. J Neurosci Res. 2004 May 1;76(3):296-305 |
1 | J:190078 Mire E, Mezzera C, Leyva-Diaz E, Paternain AV, Squarzoni P, Bluy L, Castillo-Paterna M, Lopez MJ, Peregrin S, Tessier-Lavigne M, Garel S, Galceran J, Lerma J, Lopez-Bendito G, Spontaneous activity regulates Robo1 transcription to mediate a switch in thalamocortical axon growth. Nat Neurosci. 2012 Aug;15(8):1134-43 |
1 | J:132671 Moers A, Nurnberg A, Goebbels S, Wettschureck N, Offermanns S, Galpha12/Galpha13 deficiency causes localized overmigration of neurons in the developing cerebral and cerebellar cortices. Mol Cell Biol. 2008 Mar;28(5):1480-8 |
1 | J:17458 Ninomiya T, Vuillemin M, Walter-Barakat I, Winking H, Pexieder T, Droz B, Mouse fetal trisomy 13 and hypotrophy of the spinal cord: effect on calbindin-D28k and calretinin expressed by neurons of the spinal cord and dorsal root ganglia. Neuroscience. 1993 Dec;57(4):1109-20 |
1 | J:154587 Niquille M, Garel S, Mann F, Hornung JP, Otsmane B, Chevalley S, Parras C, Guillemot F, Gaspar P, Yanagawa Y, Lebrand C, Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C. PLoS Biol. 2009 Oct;7(10):e1000230 |
1* | J:25502 Ogawa M, Miyata T, Nakajima K, Yagyu K, Seike M, Ikenaka K, Yamamoto H, Mikoshiba K, The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons. Neuron. 1995 MAY;14(5):899-912 |
1 | J:187391 Pacal M, Bremner R, Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Dev Dyn. 2012 Oct;241(10):1525-44 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1* | J:77124 Shinozaki K, Miyagi T, Yoshida M, Miyata T, Ogawa M, Aizawa S, Suda Y, Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double mutant cerebral cortex. Development. 2002 Jul;129(14):3479-92 |
1 | J:110263 Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM, Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat Neurosci. 2006 Jun;9(6):787-97 |
1 | J:111137 Thompson H, Camand O, Barker D, Erskine L, Slit proteins regulate distinct aspects of retinal ganglion cell axon guidance within dorsal and ventral retina. J Neurosci. 2006 Aug 2;26(31):8082-91 |
1 | J:308798 Wittmann MT, Katada S, Sock E, Kirchner P, Ekici AB, Wegner M, Nakashima K, Lie DC, Reis A, scRNA sequencing uncovers a TCF4-dependent transcription factor network regulating commissure development in mouse. Development. 2021 Jul 15;148(14):dev196022 |
1 | J:108702 Zhang CL, Zou Y, Yu RT, Gage FH, Evans RM, Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes Dev. 2006 May 15;20(10):1308-20 |
1* | J:59182 Zhou C, Qiu Y, Pereira FA, Crair MC, Tsai SY, Tsai MJ, The nuclear orphan receptor COUP-TFI is required for differentiation of subplate neurons and guidance of thalamocortical axons. Neuron. 1999 Dec;24(4):847-59 |
Calca calcitonin/calcitonin-related polypeptide, alpha (Synonyms: alpha CGRP, CA, Calc, Cgrp, Ct, CT, Ctn) | |
Results | Reference |
1 | J:105292 Anderson RB, Stewart AL, Young HM, Phenotypes of neural-crest-derived cells in vagal and sacral pathways. Cell Tissue Res. 2006 Jan;323(1):11-25 |
1 | J:30368 Bidegain M, Roos BA, Hill EL, Howard GA, Balkan W, Calcitonin gene-related peptide (CGRP) in the developing mouse limb. Endocr Res. 1995 Nov;21(4):743-55 |
1* | J:171712 Bird AD, Flecknoe SJ, Tan KH, Olsson PF, Antony N, Mantamadiotis T, Hooper SB, Cole TJ, cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development. PLoS One. 2011;6(3):e17843 |
1* | J:171072 Carre A, Rachdi L, Tron E, Richard B, Castanet M, Schlumberger M, Bidart JM, Szinnai G, Polak M, Hes1 is required for appropriate morphogenesis and differentiation during mouse thyroid gland development. PLoS One. 2011;6(2):e16752 |
1 | J:106971 Chen CL, Broom DC, Liu Y, de Nooij JC, Li Z, Cen C, Samad OA, Jessell TM, Woolf CJ, Ma Q, Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain. Neuron. 2006 Feb 2;49(3):365-77 |
1 | J:336102 Eenjes E, Benthem F, Boerema-de Munck A, Buscop-van Kempen M, Tibboel D, Rottier RJ, Distinct roles for SOX2 and SOX21 in differentiation, distribution and maturation of pulmonary neuroendocrine cells. Cell Mol Life Sci. 2023 Mar 3;80(3):79 |
1 | J:85092 Funakoshi K, Goris RC, Kadota T, Atobe Y, Nakano M, Kishida R, Prenatal development of peptidergic primary afferent projections to mouse lumbosacral autonomic preganglionic cell columns. Brain Res Dev Brain Res. 2003 Aug 12;144(1):107-19 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1 | J:345844 Guo Y, Xiang P, Sun X, Liu W, Zhou J, Yin B, Hou L, Qiang B, Li H, Shu P, Peng X, Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy. Signal Transduct Target Ther. 2024 Feb 14;9(1):32 |
1 | J:306265 Hao MM, Fung C, Boesmans W, Lowette K, Tack J, Vanden Berghe P, Development of the intrinsic innervation of the small bowel mucosa and villi. Am J Physiol Gastrointest Liver Physiol. 2020 Jan 1;318(1):G53-G65 |
1 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1* | J:150882 Ichikawa H, Terayama R, Yamaai T, Jacobowitz DM, Qiu F, Xiang M, Sugimoto T, Brn-3a deficiency transiently increases expression of calbindin D-28 k and calretinin in the trigeminal ganglion during embryonic development. Cell Mol Neurobiol. 2009 Jul;29(5):691-8 |
1* | J:228519 Jia S, Wildner H, Birchmeier C, Insm1 controls the differentiation of pulmonary neuroendocrine cells by repressing Hes1. Dev Biol. 2015 Dec 1;408(1):90-8 |
1 | J:184011 John A, Brylka H, Wiegreffe C, Simon R, Liu P, Juttner R, Crenshaw EB 3rd, Luyten FP, Jenkins NA, Copeland NG, Birchmeier C, Britsch S, Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. Development. 2012 May;139(10):1831-41 |
1 | J:146225 Kameda Y, Ito M, Nishimaki T, Gotoh N, FRS2alpha is required for the separation, migration, and survival of pharyngeal-endoderm derived organs including thyroid, ultimobranchial body, parathyroid, and thymus. Dev Dyn. 2009 Mar;238(3):503-13 |
1* | J:231841 Kim J, Sunagawa M, Kobayashi S, Shin T, Takayama C, Developmental localization of calcitonin gene-related peptide in dorsal sensory axons and ventral motor neurons of mouse cervical spinal cord. Neurosci Res. 2016 Apr;105:42-8 |
1 | J:37118 McEvilly RJ, Erkman L, Luo L, Sawchenko PE, Ryan AF, Rosenfeld MG, Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature. 1996 Dec 12;384(6609):574-7 |
1* | J:84449 Meunier D, Aubin J, Jeannotte L, Perturbed thyroid morphology and transient hypothyroidism symptoms in Hoxa5 mutant mice. Dev Dyn. 2003 Jul;227(3):367-78 |
1 | J:358157 N'Guetta PY, McLarnon SR, Tassou A, Geron M, Shirvan S, Hill RZ, Scherrer G, O'Brien LL, Comprehensive mapping of sensory and sympathetic innervation of the developing kidney. Cell Rep. 2024 Oct 22;43(10):114860 |
1 | J:108169 Ruan HZ, Moules E, Burnstock G, Changes in P2X3 purinoceptors in sensory ganglia of the mouse during embryonic and postnatal development. Histochem Cell Biol. 2004 Dec;122(6):539-51 |
1 | J:277336 Turco AE, Cadena MT, Zhang HL, Sandhu JK, Oakes SR, Chathurvedula T, Peterson RE, Keast JR, Vezina CM, A temporal and spatial map of axons in developing mouse prostate. Histochem Cell Biol. 2019 Jul;152(1):35-45 |
1* | J:36520 Wakisaka S, Miyawaki Y, Youn SH, Kato J, Kurisu K, Protein gene-product 9.5 in developing mouse circumvallate papilla: comparison with neuron-specific enolase and calcitonin gene-related peptide. Anat Embryol (Berl). 1996 Oct;194(4):365-72 |
1 | J:82377 Watkins DN, Berman DM, Burkholder SG, Wang B, Beachy PA, Baylin SB, Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer. Nature. 2003 Mar 20;422(6929):313-7 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
1 | J:319016 Yan R, Huang T, Xie Z, Xia G, Qian H, Zhao X, Cheng L, Lmx1b controls peptide phenotypes in serotonergic and dopaminergic neurons. Acta Biochim Biophys Sin (Shanghai). 2013 May;45(5):345-52 |
Cald1 caldesmon 1 (Synonyms: 4833423D12Rik, C920027I18Rik, MGC:30319) | |
Results | Reference |
1* | J:162756 Bergwerff M, DeRuiter MC, Hall S, Poelmann RE, Gittenberger-de Groot AC, Unique vascular morphology of the fourth aortic arches: possible implications for pathogenesis of type-B aortic arch interruption and anomalous right subclavian artery. Cardiovasc Res. 1999 Oct;44(1):185-96 |
1* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
Calm1 calmodulin 1 | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Calm4 calmodulin 4 (Synonyms: 2310037J09Rik, DD112, Scarf) | |
Results | Reference |
1 | J:320850 Lessard JC, Kalinin A, Bible PW, Morasso MI, Calmodulin 4 is dispensable for epidermal barrier formation and wound healing in mice. Exp Dermatol. 2015 Jan;24(1):55-7 |
Calr calreticulin (Synonyms: Calregulin, CRT) | |
Results | Reference |
1 | J:122471 Hattori K, Nakamura K, Hisatomi Y, Matsumoto S, Suzuki M, Harvey RP, Kurihara H, Hattori S, Yamamoto T, Michalak M, Endo F, Arrhythmia induced by spatiotemporal overexpression of calreticulin in the heart. Mol Genet Metab. 2007 Jul;91(3):285-93 |
1 | J:128422 Zhang X, Szabo E, Michalak M, Opas M, Endoplasmic reticulum stress during the embryonic development of the central nervous system in the mouse. Int J Dev Neurosci. 2007 Nov;25(7):455-63 |
Calu calumenin (Synonyms: 9530075H20Rik) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:88982 Jung DH, Kim do H, Characterization of isoforms and genomic organization of mouse calumenin. Gene. 2004 Apr 3;327(2):185-94 |
Camk2a calcium/calmodulin-dependent protein kinase II alpha (Synonyms: alpha-CaMKII, mKIAA0968) | |
Results | Reference |
1 | J:55853 Bayer KU, Lohler J, Schulman H, Harbers K, Developmental expression of the CaM kinase II isoforms: ubiquitous gamma-and delta-CaM kinase II are the early isoforms and most abundant in the developing nervous system. Brain Res Mol Brain Res. 1999 Jun 18;70(1):147-54 |
1* | J:127237 Belz T, Liu HK, Bock D, Takacs A, Vogt M, Wintermantel T, Brandwein C, Gass P, Greiner E, Schutz G, Inactivation of the gene for the nuclear receptor tailless in the brain preserving its function in the eye. Eur J Neurosci. 2007 Oct;26(8):2222-7 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
1 | J:250166 Liu K, Lei R, Li Q, Wang XX, Wu Q, An P, Zhang J, Zhu M, Xu Z, Hong Y, Wang F, Shen Y, Li H, Li H, Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity. Sci Rep. 2016 Feb 16;6:21019 |
Camk2b calcium/calmodulin-dependent protein kinase II, beta (Synonyms: CaMK II) | |
Results | Reference |
1 | J:55853 Bayer KU, Lohler J, Schulman H, Harbers K, Developmental expression of the CaM kinase II isoforms: ubiquitous gamma-and delta-CaM kinase II are the early isoforms and most abundant in the developing nervous system. Brain Res Mol Brain Res. 1999 Jun 18;70(1):147-54 |
Camk2d calcium/calmodulin-dependent protein kinase II, delta (Synonyms: 2810011D23Rik, 8030469K03Rik, CaMK II, MGC:60852) | |
Results | Reference |
1 | J:55853 Bayer KU, Lohler J, Schulman H, Harbers K, Developmental expression of the CaM kinase II isoforms: ubiquitous gamma-and delta-CaM kinase II are the early isoforms and most abundant in the developing nervous system. Brain Res Mol Brain Res. 1999 Jun 18;70(1):147-54 |
Camk2g calcium/calmodulin-dependent protein kinase II gamma (Synonyms: 5930429P18Rik, Ca2+/calmodulin-dependent protein kinase II, Camkg, CaMK II) | |
Results | Reference |
1 | J:55853 Bayer KU, Lohler J, Schulman H, Harbers K, Developmental expression of the CaM kinase II isoforms: ubiquitous gamma-and delta-CaM kinase II are the early isoforms and most abundant in the developing nervous system. Brain Res Mol Brain Res. 1999 Jun 18;70(1):147-54 |
Camsap1 calmodulin regulated spectrin-associated protein 1 (Synonyms: 9530003A05Rik, PRO2405) | |
Results | Reference |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
Canx calnexin (Synonyms: 1110069N15Rik, CNX) | |
Results | Reference |
1* | J:325291 Coe H, Bedard K, Groenendyk J, Jung J, Michalak M, Endoplasmic reticulum stress in the absence of calnexin. Cell Stress Chaperones. 2008 Dec;13(4):497-507 |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
1 | J:128422 Zhang X, Szabo E, Michalak M, Opas M, Endoplasmic reticulum stress during the embryonic development of the central nervous system in the mouse. Int J Dev Neurosci. 2007 Nov;25(7):455-63 |
Cap1 cyclase associated actin cytoskeleton regulatory protein 1 | |
Results | Reference |
1* | J:333563 Schneider F, Duong TA, Metz I, Winkelmeier J, Hubner CA, Endesfelder U, Rust MB, Mutual functional dependence of cyclase-associated protein 1 (CAP1) and cofilin1 in neuronal actin dynamics and growth cone function. Prog Neurobiol. 2021 Jul;202:102050 |
1* | J:309167 Schneider F, Metz I, Khudayberdiev S, Rust MB, Functional Redundancy of Cyclase-Associated Proteins CAP1 and CAP2 in Differentiating Neurons. Cells. 2021 Jun 17;10(6) |
Cap2 cyclase associated actin cytoskeleton regulatory protein 2 (Synonyms: 2810452G09Rik) | |
Results | Reference |
1* | J:309167 Schneider F, Metz I, Khudayberdiev S, Rust MB, Functional Redundancy of Cyclase-Associated Proteins CAP1 and CAP2 in Differentiating Neurons. Cells. 2021 Jun 17;10(6) |
Capg capping actin protein, gelsolin like (Synonyms: gCap39, mbh1) | |
Results | Reference |
1 | J:56669 Arai M, Kwiatkowski DJ, Differential developmentally regulated expression of gelsolin family members in the mouse. Dev Dyn. 1999 Aug;215(4):297-307 |
Capn1 calpain 1 (Synonyms: Capa-1, Capa1, mu-calpin) | |
Results | Reference |
1* | J:316578 Lade A, Ranganathan S, Luo J, Monga SP, Calpain induces N-terminal truncation of beta-catenin in normal murine liver development: diagnostic implications in hepatoblastomas. J Biol Chem. 2012 Jun 29;287(27):22789-98 |
1 | J:200747 Tonami K, Hata S, Ojima K, Ono Y, Kurihara Y, Amano T, Sato T, Kawamura Y, Kurihara H, Sorimachi H, Calpain-6 deficiency promotes skeletal muscle development and regeneration. PLoS Genet. 2013 Aug;9(8):e1003668 |
Capn2 calpain 2 (Synonyms: Capa-2, Capa2, m-calpain) | |
Results | Reference |
1 | J:82698 Reed NA, Castellini MA, Ma H, Shearer TR, Duncan MK, Protein expression patterns for ubiquitous and tissue specific calpains in the developing mouse lens. Exp Eye Res. 2003 Apr;76(4):433-43 |
Capn3 calpain 3 (Synonyms: Capa-3, Capa3, Lp82, p94) | |
Results | Reference |
1* | J:59885 Fougerousse F, Bullen P, Herasse M, Lindsay S, Richard I, Wilson D, Suel L, Durand M, Robson S, Abitbol M, Beckmann JS, Strachan T, Human-mouse differences in the embryonic expression patterns of developmental control genes and disease genes. Hum Mol Genet. 2000 Jan 22;9(2):165-73 |
2* | J:55110 Herasse M, Ono Y, Fougerousse F, Kimura E, Stockholm D, Beley C, Montarras D, Pinset C, Sorimachi H, Suzuki K, Beckmann JS, Richard I, Expression and functional characteristics of calpain 3 isoforms generated through tissue-specific transcriptional and posttranscriptional events. Mol Cell Biol. 1999 Jun;19(6):4047-55 |
1 | J:82698 Reed NA, Castellini MA, Ma H, Shearer TR, Duncan MK, Protein expression patterns for ubiquitous and tissue specific calpains in the developing mouse lens. Exp Eye Res. 2003 Apr;76(4):433-43 |
1 | J:201986 Sun M, Holter SM, Stepan J, Garrett L, Genius J, Kremmer E, Hrabe de Angelis M, Wurst W, Lie DC, Bally-Cuif L, Eder M, Rujescu D, Graw J, Crybb2 coding for betaB2-crystallin affects sensorimotor gating and hippocampal function. Mamm Genome. 2013 Oct;24(9-10):333-48 |
Capn5 calpain 5 | |
Results | Reference |
1* | J:58554 Dear TN, Boehm T, Diverse mRNA expression patterns of the mouse calpain genes Capn5, Capn6 and Capn11 during development. Mech Dev. 1999 Dec;89(1-2):201-9 |
Capn6 calpain 6 | |
Results | Reference |
1* | J:58554 Dear TN, Boehm T, Diverse mRNA expression patterns of the mouse calpain genes Capn5, Capn6 and Capn11 during development. Mech Dev. 1999 Dec;89(1-2):201-9 |
1* | J:296375 Holmes G, Gonzalez-Reiche AS, Lu N, Zhou X, Rivera J, Kriti D, Sebra R, Williams AA, Donovan MJ, Potter SS, Pinto D, Zhang B, van Bakel H, Jabs EW, Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis. Cell Rep. 2020 Jul 7;32(1):107871 |
2 | J:200747 Tonami K, Hata S, Ojima K, Ono Y, Kurihara Y, Amano T, Sato T, Kawamura Y, Kurihara H, Sorimachi H, Calpain-6 deficiency promotes skeletal muscle development and regeneration. PLoS Genet. 2013 Aug;9(8):e1003668 |
Capn7 calpain 7 (Synonyms: PalBH) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Caprin1 cell cycle associated protein 1 (Synonyms: caprin-1, Gpiap1, MMGPIP137, RNG105) | |
Results | Reference |
1* | J:225905 Dash S, Dang CA, Beebe DC, Lachke SA, Deficiency of the RNA binding protein caprin2 causes lens defects and features of peters anomaly. Dev Dyn. 2015 Oct;244(10):1313-27 |
Car2 carbonic anhydrase 2 (Synonyms: CA II, CAII, Car-2, Ltw-5, Lvtw-5) | |
Results | Reference |
1 | J:183431 Aboudehen K, Hilliard S, Saifudeen Z, El-Dahr SS, Mechanisms of p53 activation and physiological relevance in the developing kidney. Am J Physiol Renal Physiol. 2012 Apr;302(8):F928-40 |
1 | J:355097 Gao C, Chen L, Chen E, Tsilosani A, Xia Y, Zhang W, Generation of Distal Renal Segments Involves a Unique Population of Aqp2 + Progenitor Cells. J Am Soc Nephrol. 2021 Dec 1;32(12):3035-3049 |
1* | J:150394 Jouret F, Auzanneau C, Debaix H, Wada GH, Pretto C, Marbaix E, Karet FE, Courtoy PJ, Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. J Am Soc Nephrol. 2005 Nov;16(11):3235-46 |
2 | J:154841 Jouret F, Igarashi T, Gofflot F, Wilson PD, Karet FE, Thakker RV, Devuyst O, Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5. Kidney Int. 2004 Jan;65(1):198-208 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Car3 carbonic anhydrase 3 (Synonyms: Car-3) | |
Results | Reference |
1 | J:32267 Lyons GE, Buckingham ME, Tweedie S, Edwards YH, Carbonic anhydrase III, an early mesodermal marker, is expressed in embryonic mouse skeletal muscle and notochord. Development. 1991 Jan;111(1):233-44 |
Car4 carbonic anhydrase 4 (Synonyms: CA IV) | |
Results | Reference |
1 | J:297312 Gillich A, Zhang F, Farmer CG, Travaglini KJ, Tan SY, Gu M, Zhou B, Feinstein JA, Krasnow MA, Metzger RJ, Capillary cell-type specialization in the alveolus. Nature. 2020 Oct;586(7831):785-789 |
Carm1 coactivator-associated arginine methyltransferase 1 (Synonyms: Prmt4) | |
Results | Reference |
1 | J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134 |
1 | J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39 |
Carmn cardiac mesoderm enhancer-associated non-coding RNA (Synonyms: Carmen, Mir143hg) | |
Results | Reference |
1* | J:319356 Dong K, Shen J, He X, Hu G, Wang L, Osman I, Bunting KM, Dixon-Melvin R, Zheng Z, Xin H, Xiang M, Vazdarjanova A, Fulton DJR, Zhou J, CARMN Is an Evolutionarily Conserved Smooth Muscle Cell-Specific LncRNA That Maintains Contractile Phenotype by Binding Myocardin. Circulation. 2021 Dec 7;144(23):1856-1875 |
1* | J:283316 Garcia-Padilla C, Dominguez JN, Aranega AE, Franco D, Differential chamber-specific expression and regulation of long non-coding RNAs during cardiac development. Biochim Biophys Acta Gene Regul Mech. 2019 Oct;1862(10):194435 |
Cartpt CART prepropeptide (Synonyms: Cart) | |
Results | Reference |
1* | J:296652 Chan WH, Gonsalvez DG, Young HM, Southard-Smith EM, Cane KN, Anderson CR, Differences in CART expression and cell cycle behavior discriminate sympathetic neuroblast from chromaffin cell lineages in mouse sympathoadrenal cells. Dev Neurobiol. 2016 Feb;76(2):137-49 |
1 | J:308791 Kameneva P, Artemov AV, Kastriti ME, Faure L, Olsen TK, Otte J, Erickson A, Semsch B, Andersson ER, Ratz M, Frisen J, Tischler AS, de Krijger RR, Bouderlique T, Akkuratova N, Vorontsova M, Gusev O, Fried K, Sundstrom E, Mei S, Kogner P, Baryawno N, Kharchenko PV, Adameyko I, Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin. Nat Genet. 2021 May;53(5):694-706 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Casc3 exon junction complex subunit (Synonyms: Btz, Mln51) | |
Results | Reference |
2* | J:240595 Mao H, Brown HE, Silver DL, Mouse models of Casc3 reveal developmental functions distinct from other components of the exon junction complex. RNA. 2017 Jan;23(1):23-31 |
Cask calcium/calmodulin dependent serine protein kinase (Synonyms: DXPri1, DXRib1, LIN-2, mLin-2, Pals3) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
2 | J:94801 Wang TF, Ding CN, Wang GS, Luo SC, Lin YL, Ruan Y, Hevner R, Rubenstein JL, Hsueh YP, Identification of Tbr-1/CASK complex target genes in neurons. J Neurochem. 2004 Dec;91(6):1483-92 |
Casp3 caspase 3 (Synonyms: A830040C14Rik, AC-3, Apopain, Caspase-3, CC3, CPP32, mldy, Yama) | |
Results | Reference |
1 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1 | J:226941 Akerberg BN, Sarangam ML, Stankunas K, Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Dev Biol. 2015 Nov 1;407(1):158-72 |
1* | J:216142 Amann R, Wyder S, Slavotinek AM, Trueb B, The FgfrL1 receptor is required for development of slow muscle fibers. Dev Biol. 2014 Oct 15;394(2):228-41 |
1 | J:273194 Anderson SR, Zhang J, Steele MR, Romero CO, Kautzman AG, Schafer DP, Vetter ML, Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia. J Neurosci. 2019 Mar 13;39(11):2025-2040 |
1 | J:169444 Armstrong A, Ryu YK, Chieco D, Kuruvilla R, Frizzled3 Is Required for Neurogenesis and Target Innervation during Sympathetic Nervous System Development. J Neurosci. 2011 Feb 16;31(7):2371-81 |
1 | J:299451 Atkins A, Xu MJ, Li M, Rogers NP, Pryzhkova MV, Jordan PW, SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. Elife. 2020 Nov 17;9:e61171 |
1 | J:336863 Barry-Carroll L, Greulich P, Marshall AR, Riecken K, Fehse B, Askew KE, Li K, Garaschuk O, Menassa DA, Gomez-Nicola D, Microglia colonize the developing brain by clonal expansion of highly proliferative progenitors, following allometric scaling. Cell Rep. 2023 May 30;42(5):112425 |
1 | J:168326 Baydyuk M, Russell T, Liao GY, Zang K, An JJ, Reichardt LF, Xu B, TrkB receptor controls striatal formation by regulating the number of newborn striatal neurons. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1669-74 |
1 | J:162313 Bedogni F, Hodge RD, Elsen GE, Nelson BR, Daza RA, Beyer RP, Bammler TK, Rubenstein JL, Hevner RF, Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13129-34 |
1 | J:278765 Bittermann E, Abdelhamed Z, Liegel RP, Menke C, Timms A, Beier DR, Stottmann RW, Differential requirements of tubulin genes in mammalian forebrain development. PLoS Genet. 2019 Aug;15(8):e1008243 |
1 | J:132251 Boesten LS, Zadelaar SM, De Clercq S, Francoz S, van Nieuwkoop A, Biessen EA, Hofmann F, Feil S, Feil R, Jochemsen AG, Zurcher C, Havekes LM, van Vlijmen BJ, Marine JC, Mdm2, but not Mdm4, protects terminally differentiated smooth muscle cells from p53-mediated caspase-3-independent cell death. Cell Death Differ. 2006 Dec;13(12):2089-98 |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1 | J:239074 Cai H, Liu A, Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling. Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14751-14756 |
1 | J:324533 Calderon L, Weiss FD, Beagan JA, Oliveira MS, Georgieva R, Wang YF, Carroll TS, Dharmalingam G, Gong W, Tossell K, de Paola V, Whilding C, Ungless MA, Fisher AG, Phillips-Cremins JE, Merkenschlager M, Cohesin-dependence of neuronal gene expression relates to chromatin loop length. Elife. 2022 Apr 26;11:e76539 |
1 | J:177402 Carpentier R, Suner RE, van Hul N, Kopp JL, Beaudry JB, Cordi S, Antoniou A, Raynaud P, Lepreux S, Jacquemin P, Leclercq IA, Sander M, Lemaigre FP, Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells. Gastroenterology. 2011 Oct;141(4):1432-1438.e4 |
1* | J:314655 Cesca F, Yabe A, Spencer-Dene B, Arrigoni A, Al-Qatari M, Henderson D, Phillips H, Koltzenburg M, Benfenati F, Schiavo G, Kidins220/ARMS is an essential modulator of cardiovascular and nervous system development. Cell Death Dis. 2011 Nov 3;2:e226 |
1* | J:203073 Cesca F, Yabe A, Spencer-Dene B, Scholz-Starke J, Medrihan L, Maden CH, Gerhardt H, Orriss IR, Baldelli P, Al-Qatari M, Koltzenburg M, Adams RH, Benfenati F, Schiavo G, Kidins220/ARMS mediates the integration of the neurotrophin and VEGF pathways in the vascular and nervous systems. Cell Death Differ. 2012 Feb;19(2):194-208 |
1 | J:300487 Chai G, Webb A, Li C, Antaki D, Lee S, Breuss MW, Lang N, Stanley V, Anzenberg P, Yang X, Marshall T, Gaffney P, Wierenga KJ, Chung BH, Tsang MH, Pais LS, Lovgren AK, VanNoy GE, Rehm HL, Mirzaa G, Leon E, Diaz J, Neumann A, Kalverda AP, Manfield IW, Parry DA, Logan CV, Johnson CA, Bonthron DT, Valleley EMA, Issa MY, Abdel-Ghafar SF, Abdel-Hamid MS, Jennings P, Zaki MS, Sheridan E, Gleeson JG, Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 Jan 20;109(2):241-256.e9 |
1* | J:143541 Chen L, Melendez J, Campbell K, Kuan CY, Zheng Y, Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly. Dev Biol. 2009 Jan 1;325(1):162-70 |
1 | J:159824 Chen L, Mupo A, Huynh T, Cioffi S, Woods M, Jin C, McKeehan W, Thompson-Snipes L, Baldini A, Illingworth E, Tbx1 regulates Vegfr3 and is required for lymphatic vessel development. J Cell Biol. 2010 May 3;189(3):417-24 |
1* | J:330081 Chen S, Vedula RS, Cuevas-Navarro A, Lu B, Hogg SJ, Wang E, Benbarche S, Knorr K, Kim WJ, Stanley RF, Cho H, Erickson C, Singer M, Cui D, Tittley S, Durham BH, Pavletich TS, Fiala E, Walsh MF, Inoue D, Monette S, Taylor J, Rosen N, McCormick F, Lindsley RC, Castel P, Abdel-Wahab O, Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation. Cancer Discov. 2022 Oct 5;12(10):2434-2453 |
1 | J:301138 Chen SH, Lu CH, Tsai MJ, TCTP is Essential for Cell Proliferation and Survival during CNS Development. Cells. 2020 Jan 6;9(1):133 |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1 | J:102162 Cicero S, Herrup K, Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci. 2005 Oct 19;25(42):9658-68 |
1 | J:206944 Clegg JM, Conway CD, Howe KM, Price DJ, Mason JO, Turnbull JE, Basson MA, Pratt T, Heparan sulfotransferases Hs6st1 and Hs2st Keep Erk in check for mouse corpus callosum development. J Neurosci. 2014 Feb 5;34(6):2389-401 |
1 | J:179898 Coate TM, Raft S, Zhao X, Ryan AK, Crenshaw EB 3rd, Kelley MW, Otic Mesenchyme Cells Regulate Spiral Ganglion Axon Fasciculation through a Pou3f4/EphA4 Signaling Pathway. Neuron. 2012 Jan 12;73(1):49-63 |
1 | J:226819 Coate TM, Spita NA, Zhang KD, Isgrig KT, Kelley MW, Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife. 2015;4 |
1 | J:264980 Coffinier C, Jung HJ, Nobumori C, Chang S, Tu Y, Barnes RH 2nd, Yoshinaga Y, de Jong PJ, Vergnes L, Reue K, Fong LG, Young SG, Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell. 2011 Dec;22(23):4683-93 |
1 | J:180843 Davis N, Mor E, Ashery-Padan R, Roles for Dicer1 in the patterning and differentiation of the optic cup neuroepithelium. Development. 2011 Jan;138(1):127-38 |
1 | J:155846 de Lange FJ, Moorman AF, Anderson RH, Manner J, Soufan AT, de Gier-de Vries C, Schneider MD, Webb S, van den Hoff MJ, Christoffels VM, Lineage and morphogenetic analysis of the cardiac valves. Circ Res. 2004 Sep 17;95(6):645-54 |
1 | J:95327 de Melo J, Du G, Fonseca M, Gillespie LA, Turk WJ, Rubenstein JL, Eisenstat DD, Dlx1 and Dlx2 function is necessary for terminal differentiation and survival of late-born retinal ganglion cells in the developing mouse retina. Development. 2005 Jan;132(2):311-22 |
1 | J:188332 Delogu A, Sellers K, Zagoraiou L, Bocianowska-Zbrog A, Mandal S, Guimera J, Rubenstein JL, Sugden D, Jessell T, Lumsden A, Subcortical visual shell nuclei targeted by ipRGCs develop from a Sox14+-GABAergic progenitor and require Sox14 to regulate daily activity rhythms. Neuron. 2012 Aug 23;75(4):648-62 |
2 | J:360776 Di Michele M, Attina A, Roux PF, Tabet I, Laguesse S, Florido J, Houdeville M, Choquet A, Encislai B, Arena G, De Blasio C, Wendling O, Frenois FX, Papon L, Stuani L, Fuentes M, Jahannault Talignani C, Rousseau M, Guegan J, Buscail Y, Dupre P, Michaud HA, Rodier G, Bellvert F, Kulyk H, Ferraro Peyret C, Mathieu H, Close P, Rapino F, Chaveroux C, Pirot N, Rubio L, Torro A, Sorg T, Ango F, Hirtz C, Compan V, Lebigot E, Legati A, Ghezzi D, Nguyen L, David A, Sardet C, Lacroix M, Le Cam L, E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development. Nat Commun. 2025 Jan 2;16(1):67 |
1* | J:274718 Diao Y, Cui L, Chen Y, Burbridge TJ, Han W, Wirth B, Sestan N, Crair MC, Zhang J, Reciprocal Connections Between Cortex and Thalamus Contribute to Retinal Axon Targeting to Dorsal Lateral Geniculate Nucleus. Cereb Cortex. 2018 Apr 1;28(4):1168-1182 |
1 | J:147448 Ding Q, Chen H, Xie X, Libby RT, Tian N, Gan L, BARHL2 differentially regulates the development of retinal amacrine and ganglion neurons. J Neurosci. 2009 Apr 1;29(13):3992-4003 |
1 | J:207252 Drosten M, Lechuga CG, Barbacid M, Ras signaling is essential for skin development. Oncogene. 2014 May 29;33(22):2857-65 |
1* | J:305426 Du G, Oatley MJ, Law NC, Robbins C, Wu X, Oatley JM, Proper timing of a quiescence period in precursor prospermatogonia is required for stem cell pool establishment in the male germline. Development. 2021 May 1;148(9):dev194571 |
1 | J:249801 Duval C, Dilworth MR, Tunster SJ, Kimber SJ, Glazier JD, PTHrP is essential for normal morphogenetic and functional development of the murine placenta. Dev Biol. 2017 Oct 15;430(2):325-336 |
1* | J:265712 Dziedzic SA, Su Z, Jean Barrett V, Najafov A, Mookhtiar AK, Amin P, Pan H, Sun L, Zhu H, Ma A, Abbott DW, Yuan J, ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC. Nat Cell Biol. 2018 Jan;20(1):58-68 |
1 | J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82 |
1 | J:206141 Eguren M, Porlan E, Manchado E, Garcia-Higuera I, Canamero M, Farinas I, Malumbres M, The APC/C cofactor Cdh1 prevents replicative stress and p53-dependent cell death in neural progenitors. Nat Commun. 2013;4:2880 |
1 | J:71881 Enomoto H, Crawford PA, Gorodinsky A, Heuckeroth RO, Johnson EM Jr, Milbrandt J, RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neurons. Development. 2001 Oct;128(20):3963-74 |
1 | J:311814 Eom TY, Stanco A, Guo J, Wilkins G, Deslauriers D, Yan J, Monckton C, Blair J, Oon E, Perez A, Salas E, Oh A, Ghukasyan V, Snider WD, Rubenstein JL, Anton ES, Differential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration. Dev Cell. 2014 Dec 22;31(6):677-89 |
1 | J:303325 Fehrenbach MK, Tjwa M, Bechmann I, Krueger M, Decreased microglial numbers in Vav1-Cre(+):dicer knock-out mice suggest a second source of microglia beyond yolk sac macrophages. Ann Anat. 2018 Jul;218:190-198 |
1 | J:311887 Filova I, Dvorakova M, Bohuslavova R, Pavlinek A, Elliott KL, Vochyanova S, Fritzsch B, Pavlinkova G, Combined Atoh1 and Neurod1 Deletion Reveals Autonomous Growth of Auditory Nerve Fibers. Mol Neurobiol. 2020 Dec;57(12):5307-5323 |
1* | J:103134 Fischer H, Rossiter H, Ghannadan M, Jaeger K, Barresi C, Declercq W, Tschachler E, Eckhart L, Caspase-14 but not caspase-3 is processed during the development of fetal mouse epidermis. Differentiation. 2005 Oct;73(8):406-13 |
2 | J:307825 Fisher AL, Sangkhae V, Balusikova K, Palaskas NJ, Ganz T, Nemeth E, Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy. Nat Commun. 2021 Jun 29;12(1):4026 |
1 | J:104617 Fujitani Y, Fujitani S, Boyer DF, Gannon M, Kawaguchi Y, Ray M, Shiota M, Stein RW, Magnuson MA, Wright CV, Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation. Genes Dev. 2006 Jan 15;20(2):253-66 |
1 | J:149533 Fujiyama T, Yamada M, Terao M, Terashima T, Hioki H, Inoue YU, Inoue T, Masuyama N, Obata K, Yanagawa Y, Kawaguchi Y, Nabeshima Y, Hoshino M, Inhibitory and excitatory subtypes of cochlear nucleus neurons are defined by distinct bHLH transcription factors, Ptf1a and Atoh1. Development. 2009 Jun;136(12):2049-58 |
1 | J:134976 Galichet C, Guillemot F, Parras CM, Neurogenin 2 has an essential role in development of the dentate gyrus. Development. 2008 Jun;135(11):2031-41 |
1 | J:217584 Gerstmann K, Pensold D, Symmank J, Khundadze M, Hubner CA, Bolz J, Zimmer G, Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions. Development. 2015 Jan 1;142(1):140-50 |
1* | J:82456 Gianino S, Grider JR, Cresswell J, Enomoto H, Heuckeroth RO, GDNF availability determines enteric neuron number by controlling precursor proliferation. Development. 2003 May;130(10):2187-98 |
1 | J:286645 Gilet JG, Ivanova EL, Trofimova D, Rudolf G, Meziane H, Broix L, Drouot N, Courraud J, Skory V, Voulleminot P, Osipenko M, Bahi-Buisson N, Yalcin B, Birling MC, Hinckelmann MV, Kwok BH, Allingham JS, Chelly J, Conditional switching of KIF2A mutation provides new insights into cortical malformation pathogeny. Hum Mol Genet. 2020 Mar 27;29(5):766-784 |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1 | J:186396 Gruenbaum-Cohen Y, Harel I, Umansky KB, Tzahor E, Snapper SB, Shilo BZ, Schejter ED, The actin regulator N-WASp is required for muscle-cell fusion in mice. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11211-6 |
1 | J:305202 Gualtieri A, Kyprianou N, Gregory LC, Vignola ML, Nicholson JG, Tan R, Inoue SI, Scagliotti V, Casado P, Blackburn J, Abollo-Jimenez F, Marinelli E, Besser REJ, Hogler W, Karen Temple I, Davies JH, Gagunashvili A, Robinson ICAF, Camper SA, Davis SW, Cutillas PR, Gevers EF, Aoki Y, Dattani MT, Gaston-Massuet C, Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans. Nat Commun. 2021 Apr 1;12(1):2028 |
1 | J:283354 Guiu J, Hannezo E, Yui S, Demharter S, Ulyanchenko S, Maimets M, Jorgensen A, Perlman S, Lundvall L, Mamsen LS, Larsen A, Olesen RH, Andersen CY, Thuesen LL, Hare KJ, Pers TH, Khodosevich K, Simons BD, Jensen KB, Tracing the origin of adult intestinal stem cells. Nature. 2019 Jun;570(7759):107-111 |
1 | J:96397 Halfter W, Willem M, Mayer U, Basement membrane-dependent survival of retinal ganglion cells. Invest Ophthalmol Vis Sci. 2005 Mar;46(3):1000-9 |
1 | J:332234 Harada M, Akita K, Mouse vaginal development with lateral enlargement at late embryonic stages and caudal elongation after birth. Congenit Anom (Kyoto). 2022 Dec 14; |
1 | J:203586 Harder JM, Ding Q, Fernandes KA, Cherry JD, Gan L, Libby RT, BCL2L1 (BCL-X) promotes survival of adult and developing retinal ganglion cells. Mol Cell Neurosci. 2012 Aug;51(1-2):53-9 |
1* | J:137254 Harrison SJ, Parrish M, Monaghan AP, Sall3 is required for the terminal maturation of olfactory glomerular interneurons. J Comp Neurol. 2008 Apr 10;507(5):1780-94 |
1 | J:244163 Hasegawa S, Kumagai M, Hagihara M, Nishimaru H, Hirano K, Kaneko R, Okayama A, Hirayama T, Sanbo M, Hirabayashi M, Watanabe M, Hirabayashi T, Yagi T, Distinct and Cooperative Functions for the Protocadherin-alpha, -beta and -gamma Clusters in Neuronal Survival and Axon Targeting. Front Mol Neurosci. 2016;9:155 |
1 | J:219824 Hendley AM, Provost E, Bailey JM, Wang YJ, Cleveland MH, Blake D, Bittman RW, Roeser JC, Maitra A, Reynolds AB, Leach SD, p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas. Dev Biol. 2015 Mar 1;399(1):41-53 |
1 | J:166928 Hoeck JD, Jandke A, Blake SM, Nye E, Spencer-Dene B, Brandner S, Behrens A, Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun. Nat Neurosci. 2010 Nov;13(11):1365-72 |
1 | J:175769 Hsu SH, Zhang X, Yu C, Li ZJ, Wunder JS, Hui CC, Alman BA, Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu. Development. 2011 Sep;138(17):3791-801 |
1* | J:150882 Ichikawa H, Terayama R, Yamaai T, Jacobowitz DM, Qiu F, Xiang M, Sugimoto T, Brn-3a deficiency transiently increases expression of calbindin D-28 k and calretinin in the trigeminal ganglion during embryonic development. Cell Mol Neurobiol. 2009 Jul;29(5):691-8 |
1 | J:122204 Imai F, Hirai S, Akimoto K, Koyama H, Miyata T, Ogawa M, Noguchi S, Sasaoka T, Noda T, Ohno S, Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex. Development. 2006 May;133(9):1735-44 |
1 | J:135191 Ishimura R, Martin GR, Ackerman SL, Loss of apoptosis-inducing factor results in cell-type-specific neurogenesis defects. J Neurosci. 2008 May 7;28(19):4938-48 |
1 | J:173361 Itoh A, Horiuchi M, Wakayama K, Xu J, Bannerman P, Pleasure D, Itoh T, ZPK/DLK, a mitogen-activated protein kinase kinase kinase, is a critical mediator of programmed cell death of motoneurons. J Neurosci. 2011 May 18;31(20):7223-8 |
1 | J:215576 Itoh T, Horiuchi M, Ikeda RH Jr, Xu J, Bannerman P, Pleasure D, Penninger JM, Tournier C, Itoh A, ZPK/DLK and MKK4 form the critical gateway to axotomy-induced motoneuron death in neonates. J Neurosci. 2014 Aug 6;34(32):10729-42 |
1 | J:152424 Jacob J, Storm R, Castro DS, Milton C, Pla P, Guillemot F, Birchmeier C, Briscoe J, Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain. Development. 2009 Jul;136(14):2477-85 |
1 | J:205043 Janisch KM, Vock VM, Fleming MS, Shrestha A, Grimsley-Myers CM, Rasoul BA, Neale SA, Cupp TD, Kinchen JM, Liem KF Jr, Dwyer ND, The vertebrate-specific Kinesin-6, Kif20b, is required for normal cytokinesis of polarized cortical stem cells and cerebral cortex size. Development. 2013 Dec;140(23):4672-82 |
1 | J:330450 Ji YR, Tona Y, Wafa T, Christman ME, Tourney ED, Jiang T, Ohta S, Cheng H, Fitzgerald T, Fritzsch B, Jones SM, Cullen KE, Wu DK, Function of bidirectional sensitivity in the otolith organs established by transcription factor Emx2. Nat Commun. 2022 Oct 24;13(1):6330 |
1 | J:199663 Jiang Y, Ding Q, Xie X, Libby RT, Lefebvre V, Gan L, Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells. J Biol Chem. 2013 Jun 21;288(25):18429-38 |
1 | J:334107 Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J, Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice. Hum Mol Genet. 2022 Oct 10;31(20):3504-3520 |
1 | J:304136 Journiac N, Gilabert-Juan J, Cipriani S, Benit P, Liu X, Jacquier S, Faivre V, Delahaye-Duriez A, Csaba Z, Hourcade T, Melinte E, Lebon S, Violle-Poirsier C, Oury JF, Adle-Biassette H, Wang ZQ, Mani S, Rustin P, Gressens P, Nardelli J, Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly. Cell Rep. 2020 Apr 14;31(2):107506 |
1 | J:273296 Kaiser K, Gyllborg D, Prochazka J, Salasova A, Kompanikova P, Molina FL, Laguna-Goya R, Radaszkiewicz T, Harnos J, Prochazkova M, Potesil D, Barker RA, Casado AG, Zdrahal Z, Sedlacek R, Arenas E, Villaescusa JC, Bryja V, WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis. Nat Commun. 2019 Apr 2;10(1):1498 |
1 | J:294228 Kalailingam P, Wang KQ, Toh XR, Nguyen TQ, Chandrakanthan M, Hasan Z, Habib C, Schif A, Radio FC, Dallapiccola B, Weiss K, Nguyen LN, Deficiency of MFSD7c results in microcephaly-associated vasculopathy in Fowler syndrome. J Clin Invest. 2020 Aug 3;130(8):4081-4093 |
1 | J:249035 Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M, McGillewie L, Bar S, Minocha S, Chevalier C, Po C, Chelly J, Mandel JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, Herault Y, Collins SC, Friant S, Godin JD, Yalcin B, WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9308-E9317 |
1 | J:209564 Karaca E, Weitzer S, Pehlivan D, Shiraishi H, Gogakos T, Hanada T, Jhangiani SN, Wiszniewski W, Withers M, Campbell IM, Erdin S, Isikay S, Franco LM, Gonzaga-Jauregui C, Gambin T, Gelowani V, Hunter JV, Yesil G, Koparir E, Yilmaz S, Brown M, Briskin D, Hafner M, Morozov P, Farazi TA, Bernreuther C, Glatzel M, Trattnig S, Friske J, Kronnerwetter C, Bainbridge MN, Gezdirici A, Seven M, Muzny DM, Boerwinkle E, Ozen M, Clausen T, Tuschl T, Yuksel A, Hess A, Gibbs RA, Martinez J, Penninger JM, Lupski JR, Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function. Cell. 2014 Apr 24;157(3):636-50 |
1* | J:98918 Kassar-Duchossoy L, Giacone E, Gayraud-Morel B, Jory A, Gomes D, Tajbakhsh S, Pax3/Pax7 mark a novel population of primitive myogenic cells during development. Genes Dev. 2005 Jun 15;19(12):1426-31 |
1 | J:193056 Kechad A, Jolicoeur C, Tufford A, Mattar P, Chow RW, Harris WA, Cayouette M, Numb is required for the production of terminal asymmetric cell divisions in the developing mouse retina. J Neurosci. 2012 Nov 28;32(48):17197-210 |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1* | J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347 |
1 | J:251343 Kim YJ, Wang SZ, Tymanskyj S, Ma L, Tao HW, Zhang LI, Dcc Mediates Functional Assembly of Peripheral Auditory Circuits. Sci Rep. 2016 Apr 4;6:23799 |
1* | J:289438 Kischel A, Audouard C, Fawal MA, Davy A, Ephrin-B2 paces neuronal production in the developing neocortex. BMC Dev Biol. 2020 May 13;20(1):12 |
1 | J:170178 Kobayashi K, Umezawa K, Yasui M, Apoptosis in mouse amniotic epithelium is induced by activated macrophages through the TNF receptor type 1/TNF pathway. Biol Reprod. 2011 Feb;84(2):248-54 |
1 | J:252381 Kokavec J, Zikmund T, Savvulidi F, Kulvait V, Edelmann W, Skoultchi AI, Stopka T, The ISWI ATPase Smarca5 (Snf2h) Is Required for Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells. Stem Cells. 2017 Jun;35(6):1614-1623 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1* | J:231259 Krill KT, Gurdziel K, Heaton JH, Simon DP, Hammer GD, Dicer deficiency reveals microRNAs predicted to control gene expression in the developing adrenal cortex. Mol Endocrinol. 2013 May;27(5):754-68 |
1 | J:321428 Kruber P, Angay O, Winkler A, Bosl MR, Kneitz S, Heinze KG, Gessler M, Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation. Int J Cancer. 2019 Mar 15;144(6):1391-1400 |
1 | J:240472 Kumar N, Srivillibhuthur M, Joshi S, Walton KD, Zhou A, Faller WJ, Perekatt AO, Sansom OJ, Gumucio DL, Xing J, Bonder EM, Gao N, White E, Verzi MP, A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis. Development. 2016 Oct 15;143(20):3711-3722 |
1 | J:257613 Kuony A, Michon F, Epithelial Markers aSMA, Krt14, and Krt19 Unveil Elements of Murine Lacrimal Gland Morphogenesis and Maturation. Front Physiol. 2017;8:739 |
1 | J:343097 Kurabayashi N, Fujii K, Otobe Y, Hiroki S, Hiratsuka M, Yoshitane H, Kazuki Y, Takao K, Neocortical neuronal production and maturation defects in the TcMAC21 mouse model of Down syndrome. iScience. 2023 Dec 15;26(12):108379 |
1 | J:335074 Kuzelova A, Dupacova N, Antosova B, Sunny SS, Kozmik Z Jr, Paces J, Skoultchi AI, Stopka T, Kozmik Z, Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell Proliferation and Photoreceptor Maintenance. Cells. 2023 Mar 28;12(7) |
1* | J:121343 Lahteenmaki M, Kupari J, Airaksinen MS, Increased apoptosis of parasympathetic but not enteric neurons in mice lacking GFRalpha2. Dev Biol. 2007 May 1;305(1):325-32 |
1 | J:235955 Laitman BM, Asp L, Mariani JN, Zhang J, Liu J, Sawai S, Chapouly C, Horng S, Kramer EG, Mitiku N, Loo H, Burlant N, Pedre X, Hara Y, Nudelman G, Zaslavsky E, Lee YM, Braun DA, Lu QR, Narla G, Raine CS, Friedman SL, Casaccia P, John GR, The Transcriptional Activator Kruppel-like Factor-6 Is Required for CNS Myelination. PLoS Biol. 2016 May;14(5):e1002467 |
1 | J:254235 Lanctot AA, Guo Y, Le Y, Edens BM, Nowakowski RS, Feng Y, Loss of Brap Results in Premature G1/S Phase Transition and Impeded Neural Progenitor Differentiation. Cell Rep. 2017 Aug 1;20(5):1148-1160 |
1 | J:107096 Le Bras B, Barallobre MJ, Homman-Ludiye J, Ny A, Wyns S, Tammela T, Haiko P, Karkkainen MJ, Yuan L, Muriel MP, Chatzopoulou E, Breant C, Zalc B, Carmeliet P, Alitalo K, Eichmann A, Thomas JL, VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain. Nat Neurosci. 2006 Mar;9(3):340-8 |
1 | J:332919 Leca I, Phillips AW, Ushakova L, Cushion TD, Keays DA, Codon modification of Tuba1a alters mRNA levels and causes a severe neurodevelopmental phenotype in mice. Sci Rep. 2023 Jan 21;13(1):1215 |
1* | J:293624 Lee S, Sears MJ, Zhang Z, Li H, Salhab I, Krebs P, Xing Y, Nah HD, Williams T, Carstens RP, Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk. Development. 2020 Apr 30;147(21):dev187369 |
1 | J:181920 Lee Y, Shull ER, Frappart PO, Katyal S, Enriquez-Rios V, Zhao J, Russell HR, Brown EJ, McKinnon PJ, ATR maintains select progenitors during nervous system development. EMBO J. 2012 Mar 7;31(5):1177-89 |
1 | J:205567 Li K, Leung AW, Guo Q, Yang W, Li JY, Shp2-Dependent ERK Signaling Is Essential for Induction of Bergmann Glia and Foliation of the Cerebellum. J Neurosci. 2014 Jan 15;34(3):922-31 |
1* | J:226736 Li X, Li L, Li J, Sipple J, Schick J, Mehta PA, Davies SM, Dasgupta B, Waclaw RR, Pang Q, Concomitant inactivation of foxo3a and fancc or fancd2 reveals a two-tier protection from oxidative stress-induced hydrocephalus. Antioxid Redox Signal. 2014 Oct 20;21(12):1675-92 |
1 | J:328234 Li Y, Fan T, Li X, Liu L, Mao F, Li Y, Miao Z, Zeng C, Song W, Pan J, Zhou S, Wang H, Wang Y, Sun ZS, Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors. Cell Rep. 2022 Aug 30;40(9):111289 |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1 | J:352165 Lin Y, Tang W, Huang P, Wang Z, Duan L, Jia C, Sun R, Liu L, Shen J, Denticleless E3 ubiquitin protein ligase (DTL) maintains the proliferation and differentiation of epidermis and hair follicles during skin development. Dev Dyn. 2024 Jul;253(7):635-647 |
1 | J:272578 Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G, Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. Dev Cell. 2019 Jan 7;48(1):49-63.e7 |
1 | J:294981 Liu X, Castle V, Taketo T, Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development. Cell Death Dis. 2019 Oct 17;10(11):790 |
1* | J:175083 Lorenz A, Deutschmann M, Ahlfeld J, Prix C, Koch A, Smits R, Fodde R, Kretzschmar HA, Schuller U, Severe alterations of cerebellar cortical development after constitutive activation of wnt signaling in granule neuron precursors. Mol Cell Biol. 2011 Aug;31(16):3326-38 |
1* | J:346057 Lu D, Zhi Y, Su H, Lin X, Lin J, Shi Y, Yi W, Hong C, Zhang T, Fu Z, Chen LY, Zhao Z, Li R, Xu Z, Chen W, Wang N, Xu D, ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells. Cell Rep. 2024 Feb 24;43(3):113818 |
1 | J:177911 Lu PP, Ramanan N, Serum response factor is required for cortical axon growth but is dispensable for neurogenesis and neocortical lamination. J Neurosci. 2011 Nov 16;31(46):16651-64 |
1 | J:288654 Lun MP, Shannon ML, Keles S, Reisli I, Luche N, Ryan D, Capuder K, Notarangelo LD, Lehtinen MK, Spatiotemporal Gradient of Cortical Neuron Death Contributes to Microcephaly in Knock-In Mouse Model of Ligase 4 Syndrome. Am J Pathol. 2019 Dec;189(12):2440-2449 |
1 | J:336095 Lupan BM, Solecki RA, Musso CM, Alsina FC, Silver DL, The exon junction complex component EIF4A3 is essential for mouse and human cortical progenitor mitosis and neurogenesis. Development. 2023 May 15;150(10) |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1 | J:126705 MacLean G, Li H, Metzger D, Chambon P, Petkovich M, Apoptotic extinction of germ cells in testes of Cyp26b1 knockout mice. Endocrinology. 2007 Oct;148(10):4560-7 |
1 | J:179730 Mairet-Coello G, Tury A, Van Buskirk E, Robinson K, Genestine M, Dicicco-Bloom E, p57KIP2 regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortex. Development. 2012 Feb;139(3):475-87 |
1 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
1 | J:240536 Martin-Ibanez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Garcia-Diaz Barriga G, Edel MJ, Vicario-Abejon C, Alberch J, Girault JA, Chan S, Kastner P, Canals JM, Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017 Apr 15;144(8):1566-1577 |
1 | J:210514 Martinez P, Ferrara-Romeo I, Flores JM, Blasco MA, Essential role for the TRF2 telomere protein in adult skin homeostasis. Aging Cell. 2014 Aug;13(4):656-68 |
1 | J:112183 Mason HA, Rakowiecki SM, Gridley T, Fishell G, Loss of notch activity in the developing central nervous system leads to increased cell death. Dev Neurosci. 2006;28(1-2):49-57 |
1 | J:330324 Masuda T, Amann L, Monaco G, Sankowski R, Staszewski O, Krueger M, Del Gaudio F, He L, Paterson N, Nent E, Fernandez-Klett F, Yamasaki A, Frosch M, Fliegauf M, Bosch LFP, Ulupinar H, Hagemeyer N, Schreiner D, Dorrier C, Tsuda M, Grothe C, Joutel A, Daneman R, Betsholtz C, Lendahl U, Knobeloch KP, Lammermann T, Priller J, Kierdorf K, Prinz M, Specification of CNS macrophage subsets occurs postnatally in defined niches. Nature. 2022 Apr;604(7907):740-748 |
1 | J:178174 Matsumoto A, Susaki E, Onoyama I, Nakayama K, Hoshino M, Nakayama KI, Deregulation of the p57-E2F1-p53 axis results in nonobstructive hydrocephalus and cerebellar malformation in mice. Mol Cell Biol. 2011 Oct;31(20):4176-92 |
1 | J:302193 McDonough A, Elsen GE, Daza RM, Bachleda AR, Pizzo D, DelleTorri OM, Hevner RF, Unipolar (Dendritic) Brush Cells Are Morphologically Complex and Require Tbr2 for Differentiation and Migration. Front Neurosci. 2020;14:598548 |
1 | J:192488 McLoughlin HS, Fineberg SK, Ghosh LL, Tecedor L, Davidson BL, Dicer is required for proliferation, viability, migration and differentiation in corticoneurogenesis. Neuroscience. 2012 Oct 25;223:285-95 |
1 | J:218941 Meier F, Giesert F, Delic S, Faus-Kessler T, Matheus F, Simeone A, Holter SM, Kuhn R, Weisenhorn DM, Wurst W, Prakash N, FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS One. 2014;9(7):e101124 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1 | J:263867 Merk DJ, Ohli J, Merk ND, Thatikonda V, Morrissy S, Schoof M, Schmid SN, Harrison L, Filser S, Ahlfeld J, Erkek S, Raithatha K, Andreska T, Weisshaar M, Launspach M, Neumann JE, Shakarami M, Plenker D, Marra MA, Li Y, Mungall AJ, Moore RA, Ma Y, Jones SJM, Lutz B, Ertl-Wagner B, Rossi A, Wagener R, Siebert R, Jung A, Eberhart CG, Lach B, Sendtner M, Pfister SM, Taylor MD, Chavez L, Kool M, Schuller U, Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma. Dev Cell. 2018 Mar 26;44(6):709-724.e6 |
1 | J:275078 Minocha S, Valloton D, Arsenijevic Y, Cardinaux JR, Guidi R, Hornung JP, Lebrand C, Nkx2.1 regulates the generation of telencephalic astrocytes during embryonic development. Sci Rep. 2017 Mar 7;7:43093 |
1 | J:186318 Mohri Y, Oyama K, Sone M, Akamatsu A, Nishimori K, LGR4 Is Required for the Cell Survival of the Peripheral Mesenchyme at the Embryonic Stages of Nephrogenesis. Biosci Biotechnol Biochem. 2012 May 23;76(5):888-91 |
1 | J:306063 Morandell J, Schwarz LA, Basilico B, Tasciyan S, Dimchev G, Nicolas A, Sommer C, Kreuzinger C, Dotter CP, Knaus LS, Dobler Z, Cacci E, Schur FKM, Danzl JG, Novarino G, Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development. Nat Commun. 2021 May 24;12(1):3058 |
1 | J:205283 Munoz-Espin D, Canamero M, Maraver A, Gomez-Lopez G, Contreras J, Murillo-Cuesta S, Rodriguez-Baeza A, Varela-Nieto I, Ruberte J, Collado M, Serrano M, Programmed cell senescence during mammalian embryonic development. Cell. 2013 Nov 21;155(5):1104-18 |
1 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1 | J:355222 Nord C, Jones I, Garcia-Maestre M, Hagglund AC, Carlsson L, Reduced mTORC1-signaling in progenitor cells leads to retinal lamination deficits. Dev Dyn. 2024 Oct;253(10):922-939 |
2 | J:162564 Ohsawa S, Hamada S, Kuida K, Yoshida H, Igaki T, Miura M, Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13366-71 |
1 | J:154276 Ohsawa S, Hamada S, Yoshida H, Miura M, Caspase-mediated changes in histone H1 in early apoptosis: prolonged caspase activation in developing olfactory sensory neurons. Cell Death Differ. 2008 Sep;15(9):1429-39 |
1 | J:169044 Pan N, Jahan I, Kersigo J, Kopecky B, Santi P, Johnson S, Schmitz H, Fritzsch B, Conditional deletion of Atoh1 using Pax2-Cre results in viable mice without differentiated cochlear hair cells that have lost most of the organ of Corti. Hear Res. 2011 May;275(1-2):66-80 |
1 | J:348633 Paramore SV, Trenado-Yuste C, Sharan R, Nelson CM, Devenport D, Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation. Dev Cell. 2024 May 20;59(10):1302-1316.e5 |
1 | J:241853 Parisot J, Flore G, Bertacchi M, Studer M, COUP-TFI mitotically regulates production and migration of dentate granule cells and modulates hippocampal Cxcr4 expression. Development. 2017 Jun 01;144(11):2045-2058 |
1 | J:240000 Park JY, Hughes LJ, Moon UY, Park R, Kim SB, Tran K, Lee JS, Cho SH, Kim S, The apical complex protein Pals1 is required to maintain cerebellar progenitor cells in a proliferative state. Development. 2016 Jan 01;143(1):133-46 |
1 | J:326535 Petitpre C, Faure L, Uhl P, Fontanet P, Filova I, Pavlinkova G, Adameyko I, Hadjab S, Lallemend F, Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification. Nat Commun. 2022 Jul 5;13(1):3878 |
1 | J:191071 Petzold KM, Naumann H, Spagnoli FM, Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas. Development. 2013 Jan 1;140(1):126-35 |
1 | J:160165 Pinter R, Hindges R, Perturbations of microRNA function in mouse dicer mutants produce retinal defects and lead to aberrant axon pathfinding at the optic chiasm. PLoS One. 2010;5(4):e10021 |
1 | J:294004 Piprek RP, Kolasa M, Podkowa D, Kloc M, Kubiak JZ, N-Cadherin Is Critical for the Survival of Germ Cells, the Formation of Steroidogenic Cells, and the Architecture of Developing Mouse Gonads. Cells. 2019 Dec 11;8(12):1610 |
1* | J:325976 Piprek RP, Rams-Pociecha I, Zdanowski R, Kloc M, Kubiak JZ, Desmoplakin (Dsp) conditional knockout in NR5A1+ somatic cells affects germ cell survival in developing mouse gonads. Reproduction. 2022 Feb 24;163(4):199-207 |
1 | J:186563 Prasov L, Glaser T, Pushing the envelope of retinal ganglion cell genesis: Context dependent function of Math5 (Atoh7). Dev Biol. 2012 Aug 15;368(2):214-30 |
1 | J:255488 Premarathne S, Murtaza M, Matigian N, Jolly LA, Wood SA, Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors. Sci Rep. 2017 Aug 14;7(1):8109 |
1 | J:281274 Qu X, Violette K, Sewell-Loftin MK, Soslow J, Saint-Jean L, Hinton RB, Merryman WD, Baldwin HS, Loss of flow responsive Tie1 results in ImpairedAortic valve remodeling. Dev Biol. 2019 Nov 1;455(1):73-84 |
1 | J:203031 Rainger J, Keighren M, Keene DR, Charbonneau NL, Rainger JK, Fisher M, Mella S, Huang JT, Rose L, van't Hof R, Sakai LY, Jackson IJ, FitzPatrick DR, A Trans-Acting protein effect causes severe eye malformation in the Mp mouse. PLoS Genet. 2013;9(12):e1003998 |
1 | J:252201 Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A, p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct;137(10):2157-2167 |
1 | J:276190 Rebellato P, Kaczynska D, Kanatani S, Rayyes IA, Zhang S, Villaescusa C, Falk A, Arenas E, Hermanson O, Louhivuori L, Uhlen P, The T-type Ca(2+) Channel Cav3.2 Regulates Differentiation of Neural Progenitor Cells during Cortical Development via Caspase-3. Neuroscience. 2019 Mar 15;402:78-89 |
1 | J:217530 Renier N, Wu Z, Simon DJ, Yang J, Ariel P, Tessier-Lavigne M, iDISCO: a simple, rapid method to immunolabel large tissue samples for volume imaging. Cell. 2014 Nov 6;159(4):896-910 |
1* | J:231047 Rios-Rojas C, Spiller C, Bowles J, Koopman P, Germ cells influence cord formation and leydig cell gene expression during mouse testis development. Dev Dyn. 2016 Apr;245(4):433-44 |
1 | J:181275 Romano RA, Smalley K, Magraw C, Serna VA, Kurita T, Raghavan S, Sinha S, DeltaNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation. Development. 2012 Feb;139(4):772-82 |
1 | J:313340 Rosin JM, Kurrasch DM, Cobb J, Shox2 is required for the proper development of the facial motor nucleus and the establishment of the facial nerves. BMC Neurosci. 2015 Jul 9;16:39 |
1 | J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088 |
1 | J:353313 Roussat M, Jungas T, Audouard C, Omerani S, Medevielle F, Agius E, Davy A, Pituello F, Bel-Vialar S, Control of G(2) Phase Duration by CDC25B Modulates the Switch from Direct to Indirect Neurogenesis in the Neocortex. J Neurosci. 2023 Feb 15;43(7):1154-1165 |
1 | J:158241 Saito A, Hino S, Murakami T, Kanemoto S, Kondo S, Saitoh M, Nishimura R, Yoneda T, Furuichi T, Ikegawa S, Ikawa M, Okabe M, Imaizumi K, Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis. Nat Cell Biol. 2009 Oct;11(10):1197-204 |
1 | J:323013 Sakai D, Sugawara T, Kurokawa T, Murakami Y, Tomosugi M, Masuta H, Sakata-Haga H, Hatta T, Shoji H, Hif1alpha-dependent hypoxia signaling contributes to the survival of deep-layer neurons and cortex formation in a mouse model. Mol Brain. 2022 Mar 31;15(1):28 |
1 | J:296487 Schoof M, Launspach M, Holdhof D, Nguyen L, Engel V, Filser S, Peters F, Immenschuh J, Hellwig M, Niesen J, Mall V, Ertl-Wagner B, Hagel C, Spohn M, Lutz B, Sedlacik J, Indenbirken D, Merk DJ, Schuller U, The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration. Acta Neuropathol Commun. 2019 Dec 5;7(1):199 |
1 | J:171905 Scott A, Hasegawa H, Sakurai K, Yaron A, Cobb J, Wang F, Transcription factor short stature homeobox 2 is required for proper development of tropomyosin-related kinase B-expressing mechanosensory neurons. J Neurosci. 2011 May 4;31(18):6741-9 |
1 | J:278483 Shi L, Qalieh A, Lam MM, Keil JM, Kwan KY, Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion. Nat Commun. 2019 Jun 13;10(1):2588 |
1 | J:166950 Shi M, Zheng MH, Liu ZR, Hu ZL, Huang Y, Chen JY, Zhao G, Han H, Ding YQ, DCC is specifically required for the survival of retinal ganglion and displaced amacrine cells in the developing mouse retina. Dev Biol. 2010 Dec 1;348(1):87-96 |
1 | J:362390 Shimaoka K, Hori K, Miyashita S, Inoue YU, Tabe NKN, Sakamoto A, Hasegawa I, Nishitani K, Yamashiro K, Egusa SF, Tatsumoto S, Go Y, Abe M, Sakimura K, Inoue T, Imamura T, Hoshino M, The microcephaly-associated transcriptional regulator AUTS2 cooperates with Polycomb complex PRC2 to produce upper-layer neurons in mice. EMBO J. 2025 Mar;44(5):1354-1378 |
1 | J:339312 Sinclair-Wilson A, Lawrence A, Ferezou I, Cartonnet H, Mailhes C, Garel S, Lokmane L, Plasticity of thalamocortical axons is regulated by serotonin levels modulated by preterm birth. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2301644120 |
1 | J:148324 Stanco A, Szekeres C, Patel N, Rao S, Campbell K, Kreidberg JA, Polleux F, Anton ES, Netrin-1-alpha3beta1 integrin interactions regulate the migration of interneurons through the cortical marginal zone. Proc Natl Acad Sci U S A. 2009 May 5;106(18):7595-600 |
1 | J:159839 Stevens HE, Smith KM, Maragnoli ME, Fagel D, Borok E, Shanabrough M, Horvath TL, Vaccarino FM, Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits. J Neurosci. 2010 Apr 21;30(16):5590-602 |
1* | J:244087 Stopp S, Grundl M, Fackler M, Malkmus J, Leone M, Naumann R, Frantz S, Wolf E, von Eyss B, Engel FB, Gaubatz S, Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during development. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):8029-8034 |
1 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
1 | J:197145 Stott SR, Metzakopian E, Lin W, Kaestner KH, Hen R, Ang SL, Foxa1 and foxa2 are required for the maintenance of dopaminergic properties in ventral midbrain neurons at late embryonic stages. J Neurosci. 2013 May 1;33(18):8022-34 |
1 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
1 | J:154910 Sugiyama Y, Akimoto K, Robinson ML, Ohno S, Quinlan RA, A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol. 2009 Dec 15;336(2):246-56 |
1 | J:223316 Sun LO, Brady CM, Cahill H, Al-Khindi T, Sakuta H, Dhande OS, Noda M, Huberman AD, Nathans J, Kolodkin AL, Functional assembly of accessory optic system circuitry critical for compensatory eye movements. Neuron. 2015 May 20;86(4):971-84 |
1 | J:187029 Suzuki A, Saba R, Miyoshi K, Morita Y, Saga Y, Interaction between NANOS2 and the CCR4-NOT deadenylation complex is essential for male germ cell development in mouse. PLoS One. 2012;7(3):e33558 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
1 | J:360973 Tang I, Nisal A, Reed A, Ware TB, Johansen A, Zaki MS, Cravatt BF, Gleeson JG, Lipidomic profiling of mouse brain and human neuron cultures reveals a role for Mboat7 in mTOR-dependent neuronal migration. Sci Transl Med. 2025 Jan;17(779):eadp5247 |
1* | J:332497 Tang X, Wei W, Snowball JM, Nakayasu ES, Bell SM, Ansong C, Lin X, Whitsett JA, EMC3 regulates mesenchymal cell survival via control of the mitotic spindle assembly. iScience. 2023 Jan 20;26(1):105667 |
1 | J:156253 Tateossian H, Hardisty-Hughes RE, Morse S, Romero MR, Hilton H, Dean C, Brown SD, Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant. Pathogenetics. 2009;2(1):5 |
1 | J:287102 Tedeschi A, Almagro J, Renshaw MJ, Messal HA, Behrens A, Petronczki M, Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions. Nat Commun. 2020 Apr 8;11(1):1746 |
1 | J:333324 Tominaga K, Sakashita E, Kasashima K, Kuroiwa K, Nagao Y, Iwamori N, Endo H, Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells. Int J Mol Sci. 2023 Jan 20;24(3) |
1 | J:343099 Tonosaki M, Fujimori A, Yaoi T, Itoh K, Loss of Aspm causes increased apoptosis of developing neural cells during mouse cerebral corticogenesis. PLoS One. 2023;18(11):e0294893 |
1 | J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521 |
1 | J:228275 Udager AM, Prakash A, Saenz DA, Schinke M, Moriguchi T, Jay PY, Lim KC, Engel JD, Gumucio DL, Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3. Gastroenterology. 2014 Jan;146(1):157-65.e10 |
1* | J:314103 Ulmke PA, Sakib MS, Ditte P, Sokpor G, Kerimoglu C, Pham L, Xie Y, Mao X, Rosenbusch J, Teichmann U, Nguyen HP, Fischer A, Eichele G, Staiger JF, Tuoc T, Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex. Stem Cell Reports. 2021 Apr 13;16(4):968-984 |
1 | J:225743 Um SH, Sticker-Jantscheff M, Chau GC, Vintersten K, Mueller M, Gangloff YG, Adams RH, Spetz JF, Elghazi L, Pfluger PT, Pende M, Bernal-Mizrachi E, Tauler A, Tschop MH, Thomas G, Kozma SC, S6K1 controls pancreatic beta cell size independently of intrauterine growth restriction. J Clin Invest. 2015 Jul 1;125(7):2736-47 |
2* | J:50982 Urase K, Fujita E, Miho Y, Kouroku Y, Mukasa T, Yagi Y, Momoi MY, Momoi T, Detection of activated caspase-3 (CPP32) in the vertebrate nervous system during development by a cleavage site-directed antiserum. Brain Res Dev Brain Res. 1998 Nov 1;111(1):77-87 |
1 | J:207603 Veleva-Rotse BO, Smart JL, Baas AF, Edmonds B, Zhao ZM, Brown A, Klug LR, Hansen K, Reilly G, Gardner AP, Subbiah K, Gaucher EA, Clevers H, Barnes AP, STRAD pseudokinases regulate axogenesis and LKB1 stability. Neural Dev. 2014;9:5 |
1 | J:304564 Venkataramanappa S, Schutz D, Saaber F, Kumar PA, Abe P, Schulz S, Stumm R, The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS Genet. 2021 Mar;17(3):e1009441 |
1 | J:193303 Vidaki M, Tivodar S, Doulgeraki K, Tybulewicz V, Kessaris N, Pachnis V, Karagogeos D, Rac1-dependent cell cycle exit of MGE precursors and GABAergic interneuron migration to the cortex. Cereb Cortex. 2012 Mar;22(3):680-92 |
1* | J:104555 Viviano BL, Silverstein L, Pflederer C, Paine-Saunders S, Mills K, Saunders S, Altered hematopoiesis in glypican-3-deficient mice results in decreased osteoclast differentiation and a delay in endochondral ossification. Dev Biol. 2005 Jun 1;282(1):152-62 |
1 | J:107576 Waclaw RR, Allen ZJ 2nd, Bell SM, Erdelyi F, Szabo G, Potter SS, Campbell K, The zinc finger transcription factor Sp8 regulates the generation and diversity of olfactory bulb interneurons. Neuron. 2006 Feb 16;49(4):503-16 |
1* | J:337458 Waldhauser V, Baroti T, Frob F, Wegner M, PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12) |
1* | J:316179 Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y, An epigenetic circuit controls neurogenic programs during neocortex development. Development. 2021;148:dev199772 |
1 | J:265679 Wang B, Joo JH, Mount R, Teubner BJW, Krenzer A, Ward AL, Ichhaporia VP, Adams EJ, Khoriaty R, Peters ST, Pruett-Miller SM, Zakharenko SS, Ginsburg D, Kundu M, The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018 Aug 1;128(8):3319-3332 |
1 | J:338452 Wang D, Li H, Chandel NS, Dou Y, Yi R, MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters. Nat Commun. 2023 Jul 21;14(1):4404 |
1 | J:286823 Wang L, Tang Q, Xu J, Li H, Yang T, Li L, Machon O, Hu T, Chen Y, The transcriptional regulator MEIS2 sets up the ground state for palatal osteogenesis in mice. J Biol Chem. 2020 Apr 17;295(16):5449-5460 |
1 | J:235720 Wang PS, Chou FS, Ramachandran S, Xia S, Chen HY, Guo F, Suraneni P, Maher BJ, Li R, Crucial roles of the Arp2/3 complex during mammalian corticogenesis. Development. 2016 Aug 1;143(15):2741-52 |
1 | J:236342 Wang W, Jossin Y, Chai G, Lien WH, Tissir F, Goffinet AM, Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun. 2016 Mar 04;7:10936 |
1 | J:206929 Watson LA, Wang X, Elbert A, Kernohan KD, Galjart N, Berube NG, Dual Effect of CTCF Loss on Neuroprogenitor Differentiation and Survival. J Neurosci. 2014 Feb 19;34(8):2860-70 |
1 | J:305176 Wei Y, Han X, Zhao C, PDK1 regulates the survival of the developing cortical interneurons. Mol Brain. 2020 May 4;13(1):65 |
1 | J:316423 Whittaker DE, Oleari R, Gregory LC, Le Quesne-Stabej P, Williams HJ, Torpiano JG, Formosa N, Cachia MJ, Field D, Lettieri A, Ocaka LA, Paganoni AJ, Rajabali SH, Riegman KL, De Martini LB, Chaya T, Robinson IC, Furukawa T, Cariboni A, Basson MA, Dattani MT, A recessive PRDM13 mutation results in congenital hypogonadotropic hypogonadism and cerebellar hypoplasia. J Clin Invest. 2021 Dec 15;131(24):e141587 |
1 | J:227426 Wiegreffe C, Simon R, Peschkes K, Kling C, Strehle M, Cheng J, Srivatsa S, Liu P, Jenkins NA, Copeland NG, Tarabykin V, Britsch S, Bcl11a (Ctip1) Controls Migration of Cortical Projection Neurons through Regulation of Sema3c. Neuron. 2015 Jul 15;87(2):311-25 |
1 | J:111725 Williams ME, Lu X, McKenna WL, Washington R, Boyette A, Strickland P, Dillon A, Kaprielian Z, Tessier-Lavigne M, Hinck L, UNC5A promotes neuronal apoptosis during spinal cord development independent of netrin-1. Nat Neurosci. 2006 Aug;9(8):996-8 |
1 | J:354849 Wutikeli H, Yu Y, Zhang T, Cao J, Nawy S, Shen Y, Role of Elavl-like RNA-binding protein in retinal development and signal transduction. Biochim Biophys Acta Mol Basis Dis. 2024 Sep 20;1871(1):167518 |
1 | J:184434 Xiang C, Baubet V, Pal S, Holderbaum L, Tatard V, Jiang P, Davuluri RV, Dahmane N, RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion. Cell Death Differ. 2012 Apr;19(4):692-702 |
1 | J:342871 Xiang J, Pompetti AJ, Faranda AP, Wang Y, Novo SG, Li DW, Duncan MK, ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment. Cells. 2023 Nov 16;12(22) |
1 | J:128008 Xu H, Chen L, Baldini A, In vivo genetic ablation of the periotic mesoderm affects cell proliferation survival and differentiation in the cochlea. Dev Biol. 2007 Oct 15;310(2):329-40 |
2 | J:285763 Xu M, Han X, Liu R, Li Y, Qi C, Yang Z, Zhao C, Gao J, PDK1 Deficit Impairs the Development of the Dentate Gyrus in Mice. Cereb Cortex. 2019 Mar 1;29(3):1185-1198 |
1 | J:270427 Yabut OR, Fernandez G, Huynh T, Yoon K, Pleasure SJ, Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis. Cell Rep. 2015 Sep 29;12(12):2021-34 |
1 | J:282462 Yabut OR, Ng HX, Fernandez G, Yoon K, Kuhn J, Pleasure SJ, Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors. J Dev Biol. 2016 Dec;4(4) |
1 | J:194101 Yamaguchi S, Hong K, Liu R, Shen L, Inoue A, Diep D, Zhang K, Zhang Y, Tet1 controls meiosis by regulating meiotic gene expression. Nature. 2012 Dec 20;492(7429):443-7 |
1 | J:345074 Yamanaka T, Kurosawa M, Yoshida A, Shimogori T, Hiyama A, Maity SN, Hattori N, Matsui H, Nukina N, The transcription factor NF-YA is crucial for neural progenitor maintenance during brain development. J Biol Chem. 2024 Jan 8;300(2):105629 |
1* | J:272566 Yang R, Wang H, Kang B, Chen B, Shi Y, Yang S, Sun L, Liu Y, Xiao W, Zhang T, Yang J, Zhang Y, Zhu M, Xu P, Chang Y, Jia Y, Huang Y, CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235 |
1 | J:339368 Yao F, Huang S, Liu J, Tan C, Xu M, Wang D, Huang M, Zhu Y, Huang X, He S, Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis. Cell Death Dis. 2023 Aug 23;14(8):543 |
1 | J:243989 Yeung J, Goldowitz D, Wls expression in the rhombic lip orchestrates the embryonic development of the mouse cerebellum. Neuroscience. 2017 Jun 23;354:30-42 |
1 | J:306543 Yu Z, Zeng J, Wang J, Cui Y, Song X, Zhang Y, Cheng X, Hou N, Teng Y, Lan Y, Chen Y, Yang X, Hepatocyte growth factor-regulated tyrosine kinase substrate is essential for endothelial cell polarity and cerebrovascular stability. Cardiovasc Res. 2021 Jan 21;117(2):533-546 |
1 | J:182350 Zanucco E, Gotz R, Potapenko T, Carraretto I, Ceteci S, Ceteci F, Seeger W, Savai R, Rapp UR, Expression of B-RAF V600E in type II pneumocytes causes abnormalities in alveolar formation, airspace enlargement and tumor formation in mice. PLoS One. 2011;6(12):e29093 |
1 | J:262197 Zechel S, Fernandez-Suarez D, Ibanez CF, Cell-autonomous role of GFRalpha1 in the development of olfactory bulb GABAergic interneurons. Biol Open. 2018 May 18;7(5):bio033753 |
1 | J:299730 Zhang L, Jing H, Li H, Chen W, Luo B, Zhang H, Dong Z, Li L, Su H, Xiong WC, Mei L, Neddylation is critical to cortical development by regulating Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26448-26459 |
1 | J:312485 Zhang Q, Zhang L, Huang Y, Ma P, Mao B, Ding YQ, Song NN, Satb2 regulates the development of dopaminergic neurons in the arcuate nucleus by Dlx1. Cell Death Dis. 2021 Sep 25;12(10):879 |
1 | J:328995 Zhang SF, Dai SK, Du HZ, Wang H, Li XG, Tang Y, Liu CM, The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis. Stem Cell Reports. 2022 Sep 13;17(9):2064-2080 |
1 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
1 | J:168041 Zhu Y, Park J, Hu X, Zheng K, Li H, Cao Q, Feng GS, Qiu M, Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase. Glia. 2010 Sep;58(12):1407-14 |
Casp7 caspase 7 (Synonyms: caspase-7, CMH-1, ICE-IAP3, Mch3) | |
Results | Reference |
1 | J:196310 Ene AC, Park S, Edelmann W, Taketo T, Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression. Dev Biol. 2013 May 1;377(1):213-23 |
Casp8 caspase 8 (Synonyms: Caspase-8, FLICE, MACH, Mch5) | |
Results | Reference |
1 | J:94928 De Paepe ME, Mao Q, Embree-Ku M, Rubin LP, Luks FI, Fas/FasL-mediated apoptosis in perinatal murine lungs. Am J Physiol Lung Cell Mol Physiol. 2004 Oct;287(4):L730-42 |
1 | J:285940 Newton K, Wickliffe KE, Maltzman A, Dugger DL, Reja R, Zhang Y, Roose-Girma M, Modrusan Z, Sagolla MS, Webster JD, Dixit VM, Activity of caspase-8 determines plasticity between cell death pathways. Nature. 2019 Nov;575(7784):679-682 |
Casp9 caspase 9 (Synonyms: Caspase-9, ICE-LAP6, Mch6) | |
Results | Reference |
2 | J:196310 Ene AC, Park S, Edelmann W, Taketo T, Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression. Dev Biol. 2013 May 1;377(1):213-23 |
1 | J:294981 Liu X, Castle V, Taketo T, Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development. Cell Death Dis. 2019 Oct 17;10(11):790 |
Casp14 caspase 14 (Synonyms: MICE, mini-ICE) | |
Results | Reference |
2 | J:141601 Bayo P, Sanchis A, Bravo A, Cascallana JL, Buder K, Tuckermann J, Schutz G, Perez P, Glucocorticoid receptor is required for skin barrier competence. Endocrinology. 2008 Mar;149(3):1377-88 |
2* | J:103134 Fischer H, Rossiter H, Ghannadan M, Jaeger K, Barresi C, Declercq W, Tschachler E, Eckhart L, Caspase-14 but not caspase-3 is processed during the development of fetal mouse epidermis. Differentiation. 2005 Oct;73(8):406-13 |
1* | J:180909 Hoste E, Kemperman P, Devos M, Denecker G, Kezic S, Yau N, Gilbert B, Lippens S, De Groote P, Roelandt R, Van Damme P, Gevaert K, Presland RB, Takahara H, Puppels G, Caspers P, Vandenabeele P, Declercq W, Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin. J Invest Dermatol. 2011 Nov;131(11):2233-41 |
Casq1 calsequestrin 1 (Synonyms: CSQ, CSQ-1, CSQ1, sCSQ) | |
Results | Reference |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Casq2 calsequestrin 2 (Synonyms: cardiac calsequestrin, cCSQ, Csq2, ESTM52) | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1* | J:97586 Hong S, Kim TW, Choi I, Woo JM, Oh J, Park WJ, Kim do H, Cho C, Complementary DNA cloning, genomic characterization and expression analysis of a mammalian gene encoding histidine-rich calcium binding protein. Biochim Biophys Acta. 2005 Mar 10;1727(3):188-96 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Casr calcium-sensing receptor (Synonyms: CaR, cation sensing receptor, Gprc2a) | |
Results | Reference |
2* | J:144077 Finney BA, del Moral PM, Wilkinson WJ, Cayzac S, Cole M, Warburton D, Kemp PJ, Riccardi D, Regulation of mouse lung development by the extracellular calcium-sensing receptor, CaR. J Physiol. 2008 Dec 15;586(Pt 24):6007-19 |
Cast calpastatin | |
Results | Reference |
1 | J:126558 Chen F, Qian L, Yang ZH, Huang Y, Ngo ST, Ruan NJ, Wang J, Schneider C, Noakes PG, Ding YQ, Mei L, Luo ZG, Rapsyn interaction with calpain stabilizes AChR clusters at the neuromuscular junction. Neuron. 2007 Jul 19;55(2):247-60 |
Casz1 castor zinc finger 1 (Synonyms: 2410019P08Rik, castor, Cst, D4Ertd432e, MGC:31683) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
1 | J:285747 Liu S, Liu X, Li S, Huang X, Qian H, Jin K, Xiang M, Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5016-5027 |
3 | J:219894 Mattar P, Ericson J, Blackshaw S, Cayouette M, A conserved regulatory logic controls temporal identity in mouse neural progenitors. Neuron. 2015 Feb 4;85(3):497-504 |
Cat catalase (Synonyms: Cas-1, Cas1, Cs-1) | |
Results | Reference |
1 | J:68937 Grabenbauer M, Fahimi HD, Baumgart E, Detection of peroxisomal proteins and their mRNAs in serial sections of fetal and newborn mouse organs. J Histochem Cytochem. 2001 Feb;49(2):155-64 |
1 | J:299736 Laszlo ZI, Lele Z, Zoldi M, Miczan V, Mogor F, Simon GM, Mackie K, Kacskovics I, Cravatt BF, Katona I, ABHD4-dependent developmental anoikis safeguards the embryonic brain. Nat Commun. 2020 Aug 31;11(1):4363 |
1* | J:227089 Pirson M, Knoops B, Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617 |
Cav1 caveolin 1, caveolae protein (Synonyms: Cav-1, caveolin-1) | |
Results | Reference |
1 | J:216175 Cerqueira DM, Tran U, Romaker D, Abreu JG, Wessely O, Sterol carrier protein 2 regulates proximal tubule size in the Xenopus pronephric kidney by modulating lipid rafts. Dev Biol. 2014 Oct 1;394(1):54-64 |
1 | J:150516 Hu Z, Wang C, Xiao Y, Sheng N, Chen Y, Xu Y, Zhang L, Mo W, Jing N, Hu G, NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development. J Cell Sci. 2009 Apr 15;122(Pt 8):1145-54 |
1 | J:250555 Langen UH, Pitulescu ME, Kim JM, Enriquez-Gasca R, Sivaraj KK, Kusumbe AP, Singh A, Di Russo J, Bixel MG, Zhou B, Sorokin L, Vaquerizas JM, Adams RH, Cell-matrix signals specify bone endothelial cells during developmental osteogenesis. Nat Cell Biol. 2017 Mar;19(3):189-201 |
1 | J:322701 Liu Y, Chen Q, Jeong HW, Koh BI, Watson EC, Xu C, Stehling M, Zhou B, Adams RH, A specialized bone marrow microenvironment for fetal haematopoiesis. Nat Commun. 2022 Mar 14;13(1):1327 |
1 | J:239420 Rantakari P, Jappinen N, Lokka E, Mokkala E, Gerke H, Peuhu E, Ivaska J, Elima K, Auvinen K, Salmi M, Fetal liver endothelium regulates the seeding of tissue-resident macrophages. Nature. 2016 Oct 20;538(7625):392-396 |
2* | J:309605 Shi L, Li L, Wang D, Li S, Chen Z, An Z, Spatiotemporal expression of caveolin-1 and EMMPRIN during mouse tooth development. J Mol Histol. 2016 Jun;47(3):337-44 |
Cav2 caveolin 2 | |
Results | Reference |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Cav3 caveolin 3 (Synonyms: Cav-3, M-caveolin) | |
Results | Reference |
1 | J:221142 Beketaev I, Zhang Y, Kim EY, Yu W, Qian L, Wang J, Critical role of YY1 in cardiac morphogenesis. Dev Dyn. 2015 May;244(5):669-80 |
1 | J:183651 Kim EY, Chen L, Ma Y, Yu W, Chang J, Moskowitz IP, Wang J, Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J Mol Cell Cardiol. 2012 Mar;52(3):638-49 |
1* | J:186368 Lee CS, Yi JS, Jung SY, Kim BW, Lee NR, Choo HJ, Jang SY, Han J, Chi SG, Park M, Lee JH, Ko YG, TRIM72 negatively regulates myogenesis via targeting insulin receptor substrate-1. Cell Death Differ. 2010 Aug;17(8):1254-65 |
Cavin1 caveolae associated 1 (Synonyms: 2310075E07Rik, Cavin, cavin-1, Ptrf) | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Cbfa2t2 CBFA2/RUNX1 translocation partner 2 (Synonyms: C330013D05Rik, Cbfa2t2h, MTGR1) | |
Results | Reference |
1 | J:340417 Hendrikse LD, Haldipur P, Saulnier O, Millman J, Sjoboen AH, Erickson AW, Ong W, Gordon V, Coudiere-Morrison L, Mercier AL, Shokouhian M, Suarez RA, Ly M, Borlase S, Scott DS, Vladoiu MC, Farooq H, Sirbu O, Nakashima T, Nambu S, Funakoshi Y, Bahcheli A, Diaz-Mejia JJ, Golser J, Bach K, Phuong-Bao T, Skowron P, Wang EY, Kumar SA, Balin P, Visvanathan A, Lee JJY, Ayoub R, Chen X, Chen X, Mungall KL, Luu B, Berube P, Wang YC, Pfister SM, Kim SK, Delattre O, Bourdeaut F, Doz F, Masliah-Planchon J, Grajkowska WA, Loukides J, Dirks P, Fevre-Montange M, Jouvet A, French PJ, Kros JM, Zitterbart K, Bailey SD, Eberhart CG, Rao AAN, Giannini C, Olson JM, Garami M, Hauser P, Phillips JJ, Ra YS, de Torres C, Mora J, Li KKW, Ng HK, Poon WS, Pollack IF, Lopez-Aguilar E, Gillespie GY, Van Meter TE, Shofuda T, Vibhakar R, Thompson RC, Cooper MK, Rubin JB, Kumabe T, Jung S, Lach B, Iolascon A, Ferrucci V, de Antonellis P, Zollo M, Cinalli G, Robinson S, Stearns DS, Van Meir EG, Porrati P, Finocchiaro G, Massimino M, Carlotti CG, Faria CC, Roussel MF, Boop F, Chan JA, Aldinger KA, Razavi F, Silvestri E, McLendon RE, Thompson EM, Ansari M, Garre ML, Chico F, Eguia P, Perezpena M, Morrissy AS, Cavalli FMG, Wu X, Daniels C, Rich JN, Jones SJM, Moore RA, Marra MA, Huang X, Reimand J, Sorensen PH, Wechsler-Reya RJ, Weiss WA, Pugh TJ, Garzia L, Kleinman CL, Stein LD, Jabado N, Malkin D, Ayrault O, Golden JA, Ellison DW, Doble B, Ramaswamy V, Werbowetski-Ogilvie TE, Suzuki H, Millen KJ, Taylor MD, Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. 2022 Sep;609(7929):1021-1028 |
Cbfa2t3 CBFA2/RUNX1 translocation partner 3 (Synonyms: A630044F12Rik, Eto2, ETO-2, MTGR2) | |
Results | Reference |
1 | J:328140 Asgarian Z, Oliveira MG, Stryjewska A, Maragkos I, Rubin AN, Magno L, Pachnis V, Ghorbani M, Hiebert SW, Denaxa M, Kessaris N, MTG8 interacts with LHX6 to specify cortical interneuron subtype identity. Nat Commun. 2022 Sep 5;13(1):5217 |
1 | J:340417 Hendrikse LD, Haldipur P, Saulnier O, Millman J, Sjoboen AH, Erickson AW, Ong W, Gordon V, Coudiere-Morrison L, Mercier AL, Shokouhian M, Suarez RA, Ly M, Borlase S, Scott DS, Vladoiu MC, Farooq H, Sirbu O, Nakashima T, Nambu S, Funakoshi Y, Bahcheli A, Diaz-Mejia JJ, Golser J, Bach K, Phuong-Bao T, Skowron P, Wang EY, Kumar SA, Balin P, Visvanathan A, Lee JJY, Ayoub R, Chen X, Chen X, Mungall KL, Luu B, Berube P, Wang YC, Pfister SM, Kim SK, Delattre O, Bourdeaut F, Doz F, Masliah-Planchon J, Grajkowska WA, Loukides J, Dirks P, Fevre-Montange M, Jouvet A, French PJ, Kros JM, Zitterbart K, Bailey SD, Eberhart CG, Rao AAN, Giannini C, Olson JM, Garami M, Hauser P, Phillips JJ, Ra YS, de Torres C, Mora J, Li KKW, Ng HK, Poon WS, Pollack IF, Lopez-Aguilar E, Gillespie GY, Van Meter TE, Shofuda T, Vibhakar R, Thompson RC, Cooper MK, Rubin JB, Kumabe T, Jung S, Lach B, Iolascon A, Ferrucci V, de Antonellis P, Zollo M, Cinalli G, Robinson S, Stearns DS, Van Meir EG, Porrati P, Finocchiaro G, Massimino M, Carlotti CG, Faria CC, Roussel MF, Boop F, Chan JA, Aldinger KA, Razavi F, Silvestri E, McLendon RE, Thompson EM, Ansari M, Garre ML, Chico F, Eguia P, Perezpena M, Morrissy AS, Cavalli FMG, Wu X, Daniels C, Rich JN, Jones SJM, Moore RA, Marra MA, Huang X, Reimand J, Sorensen PH, Wechsler-Reya RJ, Weiss WA, Pugh TJ, Garzia L, Kleinman CL, Stein LD, Jabado N, Malkin D, Ayrault O, Golden JA, Ellison DW, Doble B, Ramaswamy V, Werbowetski-Ogilvie TE, Suzuki H, Millen KJ, Taylor MD, Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. 2022 Sep;609(7929):1021-1028 |
Cbfb core binding factor beta (Synonyms: PEA2, Pebp2, PEBP2b, Pebpb2) | |
Results | Reference |
2 | J:40985 Chiba N, Watanabe T, Nomura S, Tanaka Y, Minowa M, Niki M, Kanamaru R, Satake M, Differentiation dependent expression and distinct subcellular localization of the protooncogene product, PEBP2beta/CBFbeta, in muscle development. Oncogene. 1997 May 29;14(21):2543-52 |
1 | J:80669 Kundu M, Javed A, Jeon JP, Horner A, Shum L, Eckhaus M, Muenke M, Lian JB, Yang Y, Nuckolls GH, Stein GS, Liu PP, Cbfbeta interacts with Runx2 and has a critical role in bone development. Nat Genet. 2002 Dec;32(4):639-44 |
Cbln1 cerebellin 1 precursor protein | |
Results | Reference |
1* | J:112922 Miura E, Iijima T, Yuzaki M, Watanabe M, Distinct expression of Cbln family mRNAs in developing and adult mouse brains. Eur J Neurosci. 2006 Aug;24(3):750-60 |
Cbln2 cerebellin 2 precursor protein (Synonyms: 6330593N19Rik) | |
Results | Reference |
1* | J:112922 Miura E, Iijima T, Yuzaki M, Watanabe M, Distinct expression of Cbln family mRNAs in developing and adult mouse brains. Eur J Neurosci. 2006 Aug;24(3):750-60 |
Cbln3 cerebellin 3 precursor protein | |
Results | Reference |
1* | J:112922 Miura E, Iijima T, Yuzaki M, Watanabe M, Distinct expression of Cbln family mRNAs in developing and adult mouse brains. Eur J Neurosci. 2006 Aug;24(3):750-60 |
Cbln4 cerebellin 4 precursor protein | |
Results | Reference |
1* | J:112922 Miura E, Iijima T, Yuzaki M, Watanabe M, Distinct expression of Cbln family mRNAs in developing and adult mouse brains. Eur J Neurosci. 2006 Aug;24(3):750-60 |
Cbr2 carbonyl reductase 2 (Synonyms: lung carbonyl reductase, MLCR) | |
Results | Reference |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Cbx2 chromobox 2 (Synonyms: M33) | |
Results | Reference |
1* | J:47794 Hashimoto N, Brock HW, Nomura M, Kyba M, Hodgson J, Fujita Y, Takihara Y, Shimada K, Higashinakagawa T, RAE28, BMI1, and M33 are members of heterogeneous multimeric mammalian Polycomb group complexes. Biochem Biophys Res Commun. 1998 Apr 17;245(2):356-65 |
2* | J:118493 Katoh-Fukui Y, Owaki A, Toyama Y, Kusaka M, Shinohara Y, Maekawa M, Toshimori K, Morohashi K, Mouse Polycomb M33 is required for splenic vascular and adrenal gland formation through regulating Ad4BP/SF1 expression. Blood. 2005 Sep 1;106(5):1612-20 |
1 | J:783 Pearce JJ, Singh PB, Gaunt SJ, The mouse has a Polycomb-like chromobox gene. Development. 1992 Apr;114(4):921-9 |
Cbx3 chromobox 3 (Synonyms: heterochromatin protein 1 gamma, HP1g, M32) | |
Results | Reference |
1 | J:230288 Oshiro H, Hirabayashi Y, Furuta Y, Okabe S, Gotoh Y, Up-regulation of HP1gamma expression during neuronal maturation promotes axonal and dendritic development in mouse embryonic neocortex. Genes Cells. 2015 Feb;20(2):108-20 |
1 | J:194101 Yamaguchi S, Hong K, Liu R, Shen L, Inoue A, Diep D, Zhang K, Zhang Y, Tet1 controls meiosis by regulating meiotic gene expression. Nature. 2012 Dec 20;492(7429):443-7 |
Cbx4 chromobox 4 (Synonyms: MPc2, PC2) | |
Results | Reference |
1 | J:194053 Liu B, Liu YF, Du YR, Mardaryev AN, Yang W, Chen H, Xu ZM, Xu CQ, Zhang XR, Botchkarev VA, Zhang Y, Xu GL, Cbx4 regulates the proliferation of thymic epithelial cells and thymus function. Development. 2013 Feb;140(4):780-8 |
2 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
Cbx5 chromobox 5 (Synonyms: 2610029O15Rik, heterochromatin protein 1 alpha, HP1, Hp1a, HP1a, Hp1alpha) | |
Results | Reference |
1* | J:347585 Leon NY, Le TNU, Garvie A, Wong LH, Bagheri-Fam S, Harley VR, Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. iScience. 2024 May 17;27(5):109629 |
1 | J:252201 Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A, p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct;137(10):2157-2167 |
1* | J:55698 Remboutsika E, Lutz Y, Gansmuller A, Vonesch JL, Losson R, Chambon P, The putative nuclear receptor mediator TIF1alpha is tightly associated with euchromatin. J Cell Sci. 1999 Jun;112(Pt 11):1671-83 |
Cby1 chibby family member 1, beta catenin antagonist (Synonyms: 1110014P06Rik, arb1, Pgea1, PGEA14) | |
Results | Reference |
1 | J:166685 Love D, Li FQ, Burke MC, Cyge B, Ohmitsu M, Cabello J, Larson JE, Brody SL, Cohen JC, Takemaru K, Altered lung morphogenesis, epithelial cell differentiation and mechanics in mice deficient in the Wnt/beta-catenin antagonist Chibby. PLoS One. 2010;5(10):e13600 |
Ccdc39 coiled-coil domain containing 39 (Synonyms: 4921507O14Rik, b2b1304Clo, b2b1735Clo, b2b2025.1Clo, D3Ertd789e, prh) | |
Results | Reference |
1* | J:253968 Abdelhamed Z, Vuong SM, Hill L, Shula C, Timms A, Beier D, Campbell K, Mangano FT, Stottmann RW, Goto J, A mutation in Ccdc39 causes neonatal hydrocephalus with abnormal motile cilia development in mice. Development. 2018 Jan 9;145(1):dev154500 |
Ccdc40 coiled-coil domain containing 40 (Synonyms: B930008I02Rik) | |
Results | Reference |
1 | J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6 |
Ccdc80 coiled-coil domain containing 80 (Synonyms: 2610001E17Rik, DRO1, Ssg1, Urb) | |
Results | Reference |
1* | J:92004 Liu Y, Monticone M, Tonachini L, Mastrogiacomo M, Marigo V, Cancedda R, Castagnola P, URB expression in human bone marrow stromal cells and during mouse development. Biochem Biophys Res Commun. 2004 Sep 17;322(2):497-507 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Ccdc88c coiled-coil domain containing 88C (Synonyms: 0610010D24Rik, Daple) | |
Results | Reference |
1 | J:306060 Kindt KS, Akturk A, Jarysta A, Day M, Beirl A, Flonard M, Tarchini B, EMX2-GPR156-Galphai reverses hair cell orientation in mechanosensory epithelia. Nat Commun. 2021 May 17;12(1):2861 |
1* | J:253585 Siletti K, Tarchini B, Hudspeth AJ, Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11170-E11179 |
Ccdc115 coiled-coil domain containing 115 (Synonyms: 2310061I09Rik, Ccp1) | |
Results | Reference |
2* | J:105883 Pellicano F, Inglis-Broadgate SL, Pante G, Ansorge W, Iwata T, Expression of coiled-coil protein 1, a novel gene downstream of FGF2, in the developing brain. Gene Expr Patterns. 2006 Mar;6(3):285-93 |
Ccdc136 coiled-coil domain containing 136 (Synonyms: 4921511K06Rik, MGC:8047) | |
Results | Reference |
1* | J:249375 Smiley S, Nickerson PE, Comanita L, Daftarian N, El-Sehemy A, Tsai EL, Matan-Lithwick S, Yan K, Thurig S, Touahri Y, Dixit R, Aavani T, De Repentingy Y, Baker A, Tsilfidis C, Biernaskie J, Sauve Y, Schuurmans C, Kothary R, Mears AJ, Wallace VA, Establishment of a cone photoreceptor transplantation platform based on a novel cone-GFP reporter mouse line. Sci Rep. 2016 Mar 11;6:22867 |
Ccdc141 coiled-coil domain containing 141 (Synonyms: 2610301F02Rik, CAMDI, ENSMUSG00000075261) | |
Results | Reference |
2* | J:167582 Fukuda T, Sugita S, Inatome R, Yanagi S, CAMDI, a novel disrupted in schizophrenia 1 (DISC1)-binding protein, is required for radial migration. J Biol Chem. 2010 Dec 24;285(52):40554-61 |
Ccdc186 coiled-coil domain containing 186 (Synonyms: 1810028B20Rik, A630007B06Rik, Otg1) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Cck cholecystokinin | |
Results | Reference |
1 | J:119559 Bouwman J, Spijker S, Schut D, Wachtler B, Ylstra B, Smit AB, Verhage M, Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse. J Neurochem. 2006 Oct;99(1):84-96 |
1* | J:74080 Del Rio JA, Martinez A, Auladell C, Soriano E, Developmental history of the subplate and developing white matter in the murine neocortex. Neuronal organization and relationship with the main afferent systems at embryonic and perinatal stages. Cereb Cortex. 2000 Aug;10(8):784-801 |
1 | J:57954 Lay JM, Gillespie PJ, Samuelson LC, Murine prenatal expression of cholecystokinin in neural crest, enteric neurons, and enteroendocrine cells. Dev Dyn. 1999 Oct;216(2):190-200 |
1 | J:310537 Mesman S, Smidt MP, Tcf12 Is Involved in Early Cell-Fate Determination and Subset Specification of Midbrain Dopamine Neurons. Front Mol Neurosci. 2017;10:353 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
1* | J:41496 Vitale M, Vashishtha A, Linzer E, Powell DJ, Friedman JM, Molecular cloning of the mouse CCK gene: expression in different brain regions and during cortical development. Nucleic Acids Res. 1991 Jan 11;19(1):169-77 |
1 | J:319016 Yan R, Huang T, Xie Z, Xia G, Qian H, Zhao X, Cheng L, Lmx1b controls peptide phenotypes in serotonergic and dopaminergic neurons. Acta Biochim Biophys Sin (Shanghai). 2013 May;45(5):345-52 |
Cckar cholecystokinin A receptor | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Cckbr cholecystokinin B receptor (Synonyms: CCK2/gastrin, CCK2R, CCK-B/gastrin receptor, CCKR-2) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Ccl3 C-C motif chemokine ligand 3 (Synonyms: CCL3, G0S19-1, LD78alpha, macrophage inflammatory protein-1alpha, Mip1a, MIP1-(a), MIP-1 alpha, MIP1-alpha, MIP-1alpha, Scya3) | |
Results | Reference |
1* | J:289776 Mao G, Kang Y, Lin R, Hu S, Zhang Z, Li H, Liao W, Zhang Z, Long Non-coding RNA HOTTIP Promotes CCL3 Expression and Induces Cartilage Degradation by Sponging miR-455-3p. Front Cell Dev Biol. 2019;7:161 |
Ccl5 C-C motif chemokine ligand 5 (Synonyms: MuRantes, RANTES, Scya5, SISd, TCP228) | |
Results | Reference |
1 | J:269295 Kang TB, Jeong JS, Yang SH, Kovalenko A, Wallach D, Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3. Cell Death Differ. 2018 Jun;25(6):1107-1117 |
2* | J:74341 Schiltz JF, Kesari K, Ashar HR, Chada K, Hmgi-c-independent Activation of MuRantes in Vivo. Cell Growth Differ. 2002 Jan;13(1):39-45 |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
Ccl12 C-C motif chemokine ligand 12 (Synonyms: MCP-5, Scya12) | |
Results | Reference |
1 | J:187608 Longobardi L, Li T, Myers TJ, O'Rear L, Ozkan H, Li Y, Contaldo C, Spagnoli A, TGF-beta type II receptor/MCP-5 axis: at the crossroad between joint and growth plate development. Dev Cell. 2012 Jul 17;23(1):71-81 |
Ccl21a C-C motif chemokine ligand 21 (serine) (Synonyms: 6CKBAC2, 6Ckine, ALP, CKb9, Exodus-2, Gm1987, Scya21, Scya21b, SLC, Tca4) | |
Results | Reference |
1 | J:146244 Zuklys S, Gill J, Keller MP, Hauri-Hohl M, Zhanybekova S, Balciunaite G, Na KJ, Jeker LT, Hafen K, Tsukamoto N, Amagai T, Taketo MM, Krenger W, Hollander GA, Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. J Immunol. 2009 Mar 1;182(5):2997-3007 |
Ccl21b C-C motif chemokine ligand 21B (leucine) (Synonyms: 6CKBAC1, 6Ckine, CKb9, Exodus-2, Scya21, Scya21a, SLC, TCA4) | |
Results | Reference |
1 | J:146244 Zuklys S, Gill J, Keller MP, Hauri-Hohl M, Zhanybekova S, Balciunaite G, Na KJ, Jeker LT, Hafen K, Tsukamoto N, Amagai T, Taketo MM, Krenger W, Hollander GA, Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. J Immunol. 2009 Mar 1;182(5):2997-3007 |
Ccl21c C-C motif chemokine ligand 21C (leucine) (Synonyms: CKb9, exodus-2, Scya21c, SLC, TCA4) | |
Results | Reference |
1 | J:146244 Zuklys S, Gill J, Keller MP, Hauri-Hohl M, Zhanybekova S, Balciunaite G, Na KJ, Jeker LT, Hafen K, Tsukamoto N, Amagai T, Taketo MM, Krenger W, Hollander GA, Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. J Immunol. 2009 Mar 1;182(5):2997-3007 |
Ccl25 C-C motif chemokine ligand 25 (Synonyms: CKb15, Scya25, TECK) | |
Results | Reference |
1 | J:146244 Zuklys S, Gill J, Keller MP, Hauri-Hohl M, Zhanybekova S, Balciunaite G, Na KJ, Jeker LT, Hafen K, Tsukamoto N, Amagai T, Taketo MM, Krenger W, Hollander GA, Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. J Immunol. 2009 Mar 1;182(5):2997-3007 |
Ccn1 cellular communication network factor 1 (Synonyms: CCN1, Cyr61) | |
Results | Reference |
1 | J:40574 Kireeva ML, Latinkic BV, Kolesnikova TV, Chen CC, Yang GP, Abler AS , Lau LF, Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development. Exp Cell Res. 1997 May 25;233(1):63-77 |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
1* | J:2790 O'Brien TP, Lau LF, Expression of the growth factor-inducible immediate early gene cyr61 correlates with chondrogenesis during mouse embryonic development. Cell Growth Differ. 1992 Sep;3(9):645-54 |
1 | J:329315 Sheldon C, Farley A, Ma Q, Pu WT, Lin Z, Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development. Cells. 2022 Sep 10;11(18) |
Ccn2 cellular communication network factor 2 (Synonyms: Ccn2, Ctgf, Fisp12, Hcs24, hypertrophic chondrocyte-specific gene product 24) | |
Results | Reference |
1* | J:93808 Chuva de Sousa Lopes SM, Feijen A, Korving J, Korchynskyi O, Larsson J, Karlsson S, ten Dijke P, Lyons KM, Goldschmeding R, Doevendans P, Mummery CL, Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction. Dev Dyn. 2004 Nov;231(3):542-50 |
1 | J:145696 Crawford LA, Guney MA, Oh YA, Deyoung RA, Valenzuela DM, Murphy AJ, Yancopoulos GD, Lyons KM, Brigstock DR, Economides A, Gannon M, Connective Tissue Growth Factor (CTGF) Inactivation Leads to Defects in Islet Cell Lineage Allocation and {beta}-Cell Proliferation during Embryogenesis. Mol Endocrinol. 2009 Mar;23(3):324-36 |
1* | J:83516 Friedrichsen S, Heuer H, Christ S, Winckler M, Brauer D, Bauer K, Raivich G, CTGF expression during mouse embryonic development. Cell Tissue Res. 2003 May;312(2):175-88 |
1* | J:84136 Heuer H, Christ S, Friedrichsen S, Brauer D, Winckler M, Bauer K, Raivich G, Connective tissue growth factor: a novel marker of layer VII neurons in the rat cerebral cortex. Neuroscience. 2003;119(1):43-52 |
1 | J:188305 Ishijima M, Suzuki N, Hozumi K, Matsunobu T, Kosaki K, Kaneko H, Hassell JR, Arikawa-Hirasawa E, Yamada Y, Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation. Matrix Biol. 2012 May;31(4):234-45 |
1 | J:83260 Ivkovic S, Yoon BS, Popoff SN, Safadi FF, Libuda DE, Stephenson RC, Daluiski A, Lyons KM, Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development. Development. 2003 Jun;130(12):2779-91 |
1 | J:304850 Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernandez-Baldovinos J, Zhou L, Hoss C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Grone HJ, Graumann PL, Niessen CM, Offermanns S, Wickstrom SA, Worzfeld T, Mechanochemical control of epidermal stem cell divisions by B-plexins. Nat Commun. 2021 Feb 26;12(1):1308 |
1 | J:40574 Kireeva ML, Latinkic BV, Kolesnikova TV, Chen CC, Yang GP, Abler AS , Lau LF, Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development. Exp Cell Res. 1997 May 25;233(1):63-77 |
1* | J:257228 Li S, Pan Y, Differential expression of transforming growth factor-beta1, connective tissue growth factor, phosphorylated-SMAD2/3 and phosphorylated-ERK1/2 during mouse tooth development. J Mol Histol. 2017 Dec;48(5-6):347-355 |
2* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
2* | J:306471 Niki Y, Kobayashi Y, Moriyama K, Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth. Gene Expr Patterns. 2021 Jun;40:119182 |
1 | J:204753 Parada C, Li J, Iwata J, Suzuki A, Chai Y, CTGF mediates Smad-dependent transforming growth factor beta signaling to regulate mesenchymal cell proliferation during palate development. Mol Cell Biol. 2013 Sep;33(17):3482-93 |
1 | J:329315 Sheldon C, Farley A, Ma Q, Pu WT, Lin Z, Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development. Cells. 2022 Sep 10;11(18) |
1 | J:316099 Tran CM, Fujita N, Huang BL, Ong JR, Lyons KM, Shapiro IM, Risbud MV, Hypoxia-inducible factor (HIF)-1alpha and CCN2 form a regulatory circuit in hypoxic nucleus pulposus cells: CCN2 suppresses HIF-1alpha level and transcriptional activity. J Biol Chem. 2013 May 3;288(18):12654-66 |
2 | J:102996 Yamaai T, Nakanishi T, Asano M, Nawachi K, Yoshimichi G, Ohyama K, Komori T, Sugimoto T, Takigawa M, Gene expression of connective tissue growth factor (CTGF/CCN2) in calcifying tissues of normal and cbfa1-null mutant mice in late stage of embryonic development. J Bone Miner Metab. 2005;23(4):280-8 |
1* | J:239627 Yamaai T, Takigawa M, Gene Expression Analysis of CCN Proteins: Whole-Mount In Situ Hybridization of Ccn2 in Developing Calcified Tissues. Methods Mol Biol. 2017;1489:11-19 |
Ccn3 cellular communication network factor 3 (Synonyms: C130088N23Rik, CCN3, Nov) | |
Results | Reference |
1 | J:135676 Heath E, Tahri D, Andermarcher E, Schofield P, Fleming S, Boulter CA, Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene. BMC Dev Biol. 2008;8:18 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:155442 Kawaki H, Kubota S, Suzuki A, Lazar N, Yamada T, Matsumura T, Ohgawara T, Maeda T, Perbal B, Lyons KM, Takigawa M, Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage. J Bone Miner Res. 2008 Nov;23(11):1751-64 |
1 | J:65675 Natarajan D, Andermarcher E, Schofield PN, Boulter CA, Mouse nov gene is expressed in hypaxial musculature and cranial structures derived from neural crest cells and placodes. Dev Dyn. 2000 Nov;219(3):417-25 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Ccn4 cellular communication network factor 4 (Synonyms: CCN4, Elm1, Wisp1) | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Ccna1 cyclin A1 | |
Results | Reference |
1 | J:102162 Cicero S, Herrup K, Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci. 2005 Oct 19;25(42):9658-68 |
1 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:190540 Ikenishi A, Okayama H, Iwamoto N, Yoshitome S, Tane S, Nakamura K, Obayashi T, Hayashi T, Takeuchi T, Cell cycle regulation in mouse heart during embryonic and postnatal stages. Dev Growth Differ. 2012 Oct;54(8):731-8 |
1 | J:105554 Porse BT, Pedersen TA, Hasemann MS, Schuster MB, Kirstetter P, Luedde T, Damgaard I, Kurz E, Schjerling CK, Nerlov C, The proline-histidine-rich CDK2/CDK4 interaction region of C/EBPalpha is dispensable for C/EBPalpha-mediated growth regulation in vivo. Mol Cell Biol. 2006 Feb;26(3):1028-37 |
Ccna2 cyclin A2 (Synonyms: Ccn-1, Ccn1, Ccna, Cyca, CycA2) | |
Results | Reference |
1 | J:207285 Berman SD, Yuan TL, Miller ES, Lee EY, Caron A, Lees JA, The retinoblastoma protein tumor suppressor is important for appropriate osteoblast differentiation and bone development. Mol Cancer Res. 2008 Sep;6(9):1440-51 |
1* | J:108720 Berthet C, Klarmann KD, Hilton MB, Suh HC, Keller JR, Kiyokawa H, Kaldis P, Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation. Dev Cell. 2006 May;10(5):563-73 |
1 | J:102162 Cicero S, Herrup K, Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci. 2005 Oct 19;25(42):9658-68 |
1 | J:216295 Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC, FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. 2014 Nov 1;395(1):50-61 |
1 | J:190540 Ikenishi A, Okayama H, Iwamoto N, Yoshitome S, Tane S, Nakamura K, Obayashi T, Hayashi T, Takeuchi T, Cell cycle regulation in mouse heart during embryonic and postnatal stages. Dev Growth Differ. 2012 Oct;54(8):731-8 |
1 | J:101325 Persson JL, Zhang Q, Wang XY, Ravnik SE, Muhlrad S, Wolgemuth DJ, Distinct roles for the mammalian A-type cyclins during oogenesis. Reproduction. 2005 Oct;130(4):411-22 |
1 | J:105554 Porse BT, Pedersen TA, Hasemann MS, Schuster MB, Kirstetter P, Luedde T, Damgaard I, Kurz E, Schjerling CK, Nerlov C, The proline-histidine-rich CDK2/CDK4 interaction region of C/EBPalpha is dispensable for C/EBPalpha-mediated growth regulation in vivo. Mol Cell Biol. 2006 Feb;26(3):1028-37 |
1 | J:31138 Ravnik SE, Wolgemuth DJ, The developmentally restricted pattern of expression in the male germ line of a murine cyclin A, cyclin A2, suggests roles in both mitotic and meiotic cell cycles. Dev Biol. 1996 Jan 10;173(1):69-78 |
Ccnb1 cyclin B1 (Synonyms: Ccnb1-rs13, Cycb-4, MGC:18763) | |
Results | Reference |
1* | J:3021 Chapman DL, Wolgemuth DJ, Identification of a mouse B-type cyclin which exhibits developmentally regulated expression in the germ line. Mol Reprod Dev. 1992 Nov;33(3):259-69 |
2* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:216295 Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC, FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. 2014 Nov 1;395(1):50-61 |
1 | J:190540 Ikenishi A, Okayama H, Iwamoto N, Yoshitome S, Tane S, Nakamura K, Obayashi T, Hayashi T, Takeuchi T, Cell cycle regulation in mouse heart during embryonic and postnatal stages. Dev Growth Differ. 2012 Oct;54(8):731-8 |
2 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
1 | J:187391 Pacal M, Bremner R, Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Dev Dyn. 2012 Oct;241(10):1525-44 |
1 | J:329315 Sheldon C, Farley A, Ma Q, Pu WT, Lin Z, Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development. Cells. 2022 Sep 10;11(18) |
1* | J:272566 Yang R, Wang H, Kang B, Chen B, Shi Y, Yang S, Sun L, Liu Y, Xiao W, Zhang T, Yang J, Zhang Y, Zhu M, Xu P, Chang Y, Jia Y, Huang Y, CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235 |
1* | J:26610 Zhao J, Nornes HO, Neuman T, Expression of Rb, E2F1, cdc2, and D, and B cyclins in developing spinal cord. Neurosci Lett. 1995 Apr 28;190(1):49-52 |
Ccnb1ip1 cyclin B1 interacting protein 1 (Synonyms: Hei10, LOC239083, mei4) | |
Results | Reference |
1 | J:361445 Ito M, Yun Y, Kulkarni DS, Lee S, Sandhu S, Nunez B, Hu L, Lee K, Lim N, Hirota RM, Prendergast R, Huang C, Huang I, Hunter N, Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis. Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2412961121 |
Ccnb2 cyclin B2 (Synonyms: CycB2) | |
Results | Reference |
1* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1* | J:26610 Zhao J, Nornes HO, Neuman T, Expression of Rb, E2F1, cdc2, and D, and B cyclins in developing spinal cord. Neurosci Lett. 1995 Apr 28;190(1):49-52 |
Ccnb3 cyclin B3 | |
Results | Reference |
1* | J:242348 Soh YQS, Mikedis MM, Kojima M, Godfrey AK, de Rooij DG, Page DC, Meioc maintains an extended meiotic prophase I in mice. PLoS Genet. 2017 Apr;13(4):e1006704 |
Ccnd1 cyclin D1 (Synonyms: bcl-1, cD1, CycD1, Cyl-1, PRAD1) | |
Results | Reference |
2 | J:90567 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 2004 May 1;18(9):1072-87 |
1 | J:176604 Bell SM, Zhang L, Mendell A, Xu Y, Haitchi HM, Lessard JL, Whitsett JA, Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. Dev Biol. 2011 Oct 1;358(1):79-90 |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1* | J:108720 Berthet C, Klarmann KD, Hilton MB, Suh HC, Keller JR, Kiyokawa H, Kaldis P, Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation. Dev Cell. 2006 May;10(5):563-73 |
1 | J:223109 Choi JJ, Ting CT, Trogrlic L, Milevski SV, Familari M, Martinez G, de Iongh RU, A role for smoothened during murine lens and cornea development. PLoS One. 2014;9(9):e108037 |
1 | J:102162 Cicero S, Herrup K, Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci. 2005 Oct 19;25(42):9658-68 |
1* | J:80994 Ciemerych MA, Kenney AM, Sicinska E, Kalaszczynska I, Bronson RT, Rowitch DH, Gardner H, Sicinski P, Development of mice expressing a single D-type cyclin. Genes Dev. 2002 Dec 15;16(24):3277-89 |
1 | J:124435 Dyer MA, Cepko CL, p27Kip1 and p57Kip2 regulate proliferation in distinct retinal progenitor cell populations. J Neurosci. 2001 Jun 15;21(12):4259-71 |
1 | J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82 |
1 | J:176438 Esteve P, Sandonis A, Ibanez C, Shimono A, Guerrero I, Bovolenta P, Secreted frizzled-related proteins are required for Wnt/{beta}-catenin signalling activation in the vertebrate optic cup. Development. 2011 Oct;138(19):4179-84 |
1 | J:216295 Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC, FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. 2014 Nov 1;395(1):50-61 |
3 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:237540 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R, The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development. 2016 Nov 15;143(22):4182-4192 |
1 | J:217375 Heavner WE, Andoniadou CL, Pevny LH, Establishment of the neurogenic boundary of the mouse retina requires cooperation of SOX2 and WNT signaling. Neural Dev. 2014;9:27 |
1 | J:160335 Huang X, Liu J, Ketova T, Fleming JT, Grover VK, Cooper MK, Litingtung Y, Chiang C, Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8422-7 |
1 | J:231474 Hung IH, Schoenwolf GC, Lewandoski M, Ornitz DM, A combined series of Fgf9 and Fgf18 mutant alleles identifies unique and redundant roles in skeletal development. Dev Biol. 2016 Mar 1;411(1):72-84 |
1 | J:190540 Ikenishi A, Okayama H, Iwamoto N, Yoshitome S, Tane S, Nakamura K, Obayashi T, Hayashi T, Takeuchi T, Cell cycle regulation in mouse heart during embryonic and postnatal stages. Dev Growth Differ. 2012 Oct;54(8):731-8 |
2 | J:153633 Ito T, Yadav N, Lee J, Furumatsu T, Yamashita S, Yoshida K, Taniguchi N, Hashimoto M, Tsuchiya M, Ozaki T, Lotz M, Bedford MT, Asahara H, Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC Dev Biol. 2009;9:47 |
1 | J:196835 Kerr CL, Huang J, Williams T, West-Mays JA, Activation of the hedgehog signaling pathway in the developing lens stimulates ectopic FoxE3 expression and disruption in fiber cell differentiation. Invest Ophthalmol Vis Sci. 2012 Jun;53(7):3316-30 |
1 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
1 | J:208421 Klimova L, Kozmik Z, Stage-dependent requirement of neuroretinal Pax6 for lens and retina development. Development. 2014 Mar;141(6):1292-302 |
2 | J:201110 Komada M, Iguchi T, Takeda T, Ishibashi M, Sato M, Smoothened controls cyclin D2 expression and regulates the generation of intermediate progenitors in the developing cortex. Neurosci Lett. 2013 Jun 28;547:87-91 |
1 | J:167233 Lee YC, Chang CJ, Bali D, Chen YT, Yan YT, Glycogen-branching enzyme deficiency leads to abnormal cardiac development: novel insights into glycogen storage disease IV. Hum Mol Genet. 2011 Feb 1;20(3):455-65 |
1 | J:306027 Li H, Kurtzeborn K, Kupari J, Gui Y, Siefker E, Lu B, Matlik K, Olfat S, Montano-Rodriguez AR, Huh SH, Costantini F, Andressoo JO, Kuure S, Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF. Development. 2021 May 15;148(10):dev197475 |
1* | J:294282 Li L, Ruan X, Wen C, Chen P, Liu W, Zhu L, Xiang P, Zhang X, Wei Q, Hou L, Yin B, Yuan J, Qiang B, Shu P, Peng X, The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019 Jul 16;28(3):698-711.e5 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1* | J:325180 Ma M, Zhou J, Ma Z, Chen H, Li L, Hou L, Yin B, Qiang B, Shu P, Peng X, The Ash2l SDI Domain Is Required to Maintain the Stability and Binding of DPY30. Cells. 2022 Apr 25;11(9) |
1 | J:261834 Maskell LJ, Qamar K, Babakr AA, Hawkins TA, Heads RJ, Budhram-Mahadeo VS, Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart. Cell Death Dis. 2017 Jun 8;8(6):e2861 |
1 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1* | J:86666 Michno K, Boras-Granic K, Mill P, Hui CC, Hamel PA, Shh expression is required for embryonic hair follicle but not mammary gland development. Dev Biol. 2003 Dec 1;264(1):153-65 |
2 | J:171273 Nakajima K, Inagawa M, Uchida C, Okada K, Tane S, Kojima M, Kubota M, Noda M, Ogawa S, Shirato H, Sato M, Suzuki-Migishima R, Hino T, Satoh Y, Kitagawa M, Takeuchi T, Coordinated regulation of differentiation and proliferation of embryonic cardiomyocytes by a jumonji (Jarid2)-cyclin D1 pathway. Development. 2011 May;138(9):1771-82 |
1 | J:206963 Orieux G, Picault L, Slembrouck A, Roger JE, Guillonneau X, Sahel JA, Saule S, McPherson JP, Goureau O, Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells. J Neurosci. 2014 Jan 22;34(4):1530-41 |
1 | J:91004 Panhuysen M, Vogt Weisenhorn DM, Blanquet V, Brodski C, Heinzmann U, Beisker W, Wurst W, Effects of Wnt1 signaling on proliferation in the developing mid-/hindbrain region. Mol Cell Neurosci. 2004 May;26(1):101-11 |
1 | J:115956 Pogoriler J, Millen K, Utset M, Du W, Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation. Development. 2006 Oct;133(19):3929-37 |
1 | J:255488 Premarathne S, Murtaza M, Matigian N, Jolly LA, Wood SA, Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors. Sci Rep. 2017 Aug 14;7(1):8109 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1* | J:32244 Sun W, Lee DK, Lee CC, Kim K, Differential expression of D-type G1 cyclins during mouse development and liver regeneration in vivo. Mol Reprod Dev. 1996 Apr;43(4):414-20 |
1 | J:48539 Sunters A, McCluskey J, Grigoriadis AE, Control of cell cycle gene expression in bone development and during c-Fos-induced osteosarcoma formation. Dev Genet. 1998;22(4):386-97 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
1 | J:99501 Wang J, Ito T, Udaka N, Okudela K, Yazawa T, Kitamura H, PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung. Tissue Cell. 2005 Feb;37(1):25-35 |
1* | J:272566 Yang R, Wang H, Kang B, Chen B, Shi Y, Yang S, Sun L, Liu Y, Xiao W, Zhang T, Yang J, Zhang Y, Zhu M, Xu P, Chang Y, Jia Y, Huang Y, CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235 |
1* | J:120114 Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY, A biphasic pattern of gene expression during mouse retina development. BMC Dev Biol. 2006;6:48 |
1* | J:136711 Zhao H, Yang T, Madakashira BP, Thiels CA, Bechtle CA, Garcia CM, Zhang H, Yu K, Ornitz DM, Beebe DC, Robinson ML, Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. Dev Biol. 2008 Jun 15;318(2):276-88 |
1* | J:26610 Zhao J, Nornes HO, Neuman T, Expression of Rb, E2F1, cdc2, and D, and B cyclins in developing spinal cord. Neurosci Lett. 1995 Apr 28;190(1):49-52 |
1 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
1 | J:354246 Zhu S, Huo S, Wang Z, Huang C, Li C, Song H, Yang X, He R, Ding C, Qiu M, Zhu XJ, Follistatin controls the number of murine teeth by limiting TGF-beta signaling. iScience. 2024 Sep 20;27(9):110785 |
Ccnd2 cyclin D2 (Synonyms: 2600016F06Rik, cD2, Vin-1, Vin1) | |
Results | Reference |
1 | J:102162 Cicero S, Herrup K, Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci. 2005 Oct 19;25(42):9658-68 |
1* | J:80994 Ciemerych MA, Kenney AM, Sicinska E, Kalaszczynska I, Bronson RT, Rowitch DH, Gardner H, Sicinski P, Development of mice expressing a single D-type cyclin. Genes Dev. 2002 Dec 15;16(24):3277-89 |
1 | J:216295 Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC, FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. 2014 Nov 1;395(1):50-61 |
2 | J:201110 Komada M, Iguchi T, Takeda T, Ishibashi M, Sato M, Smoothened controls cyclin D2 expression and regulates the generation of intermediate progenitors in the developing cortex. Neurosci Lett. 2013 Jun 28;547:87-91 |
1 | J:311844 Landin MA, Nygard S, Shabestari MG, Babaie E, Reseland JE, Osmundsen H, Mapping the global mRNA transcriptome during development of the murine first molar. Front Genet. 2015;6:47 |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
2 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
1 | J:241892 Marcucci F, Murcia-Belmonte V, Wang Q, Coca Y, Ferreiro-Galve S, Kuwajima T, Khalid S, Ross ME, Mason C, Herrera E, The Ciliary Margin Zone of the Mammalian Retina Generates Retinal Ganglion Cells. Cell Rep. 2016 Dec 20;17(12):3153-3164 |
1* | J:182715 Monahan P, Himes AD, Parfieniuk A, Raetzman LT, p21, an important mediator of quiescence during pituitary tumor formation, is dispensable for normal pituitary development during embryogenesis. Mech Dev. 2012 Jan-Feb;128(11-12):640-52 |
1 | J:157341 Monahan P, Rybak S, Raetzman LT, The notch target gene HES1 regulates cell cycle inhibitor expression in the developing pituitary. Endocrinology. 2009 Sep;150(9):4386-94 |
1 | J:115956 Pogoriler J, Millen K, Utset M, Du W, Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation. Development. 2006 Oct;133(19):3929-37 |
1 | J:30450 Ross ME, Carter ML, Lee JH, MN20, a D2 cyclin, is transiently expressed in selected neural populations during embryogenesis. J Neurosci. 1996 Jan;16(1):210-9 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
1 | J:255944 Wang Q, Marcucci F, Cerullo I, Mason C, Ipsilateral and Contralateral Retinal Ganglion Cells Express Distinct Genes during Decussation at the Optic Chiasm. eNeuro. 2016 Nov-Dec;3(6):ENEURO.0169-16.2016 |
1 | J:96246 Ward RD, Raetzman LT, Suh H, Stone BM, Nasonkin IO, Camper SA, Role of PROP1 in pituitary gland growth. Mol Endocrinol. 2005 Mar;19(3):698-710 |
1 | J:305176 Wei Y, Han X, Zhao C, PDK1 regulates the survival of the developing cortical interneurons. Mol Brain. 2020 May 4;13(1):65 |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
1 | J:264522 Youngblood JL, Coleman TF, Davis SW, Regulation of Pituitary Progenitor Differentiation by beta-Catenin. Endocrinology. 2018 Sep 1;159(9):3287-3305 |
1* | J:136711 Zhao H, Yang T, Madakashira BP, Thiels CA, Bechtle CA, Garcia CM, Zhang H, Yu K, Ornitz DM, Beebe DC, Robinson ML, Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. Dev Biol. 2008 Jun 15;318(2):276-88 |
1* | J:26610 Zhao J, Nornes HO, Neuman T, Expression of Rb, E2F1, cdc2, and D, and B cyclins in developing spinal cord. Neurosci Lett. 1995 Apr 28;190(1):49-52 |
Ccnd3 cyclin D3 (Synonyms: 9230106B05Rik) | |
Results | Reference |
1 | J:102162 Cicero S, Herrup K, Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci. 2005 Oct 19;25(42):9658-68 |
1* | J:80994 Ciemerych MA, Kenney AM, Sicinska E, Kalaszczynska I, Bronson RT, Rowitch DH, Gardner H, Sicinski P, Development of mice expressing a single D-type cyclin. Genes Dev. 2002 Dec 15;16(24):3277-89 |
1 | J:124435 Dyer MA, Cepko CL, p27Kip1 and p57Kip2 regulate proliferation in distinct retinal progenitor cell populations. J Neurosci. 2001 Jun 15;21(12):4259-71 |
1 | J:217375 Heavner WE, Andoniadou CL, Pevny LH, Establishment of the neurogenic boundary of the mouse retina requires cooperation of SOX2 and WNT signaling. Neural Dev. 2014;9:27 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
2 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
1* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1* | J:32244 Sun W, Lee DK, Lee CC, Kim K, Differential expression of D-type G1 cyclins during mouse development and liver regeneration in vivo. Mol Reprod Dev. 1996 Apr;43(4):414-20 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Ccne1 cyclin E1 (Synonyms: CycE1, cyclin E) | |
Results | Reference |
1 | J:207285 Berman SD, Yuan TL, Miller ES, Lee EY, Caron A, Lees JA, The retinoblastoma protein tumor suppressor is important for appropriate osteoblast differentiation and bone development. Mol Cancer Res. 2008 Sep;6(9):1440-51 |
1* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1* | J:168656 Ikeda Y, Matsunaga Y, Takiguchi M, Ikeda MA, Expression of cyclin E in postmitotic neurons during development and in the adult mouse brain. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):64-71 |
1 | J:190540 Ikenishi A, Okayama H, Iwamoto N, Yoshitome S, Tane S, Nakamura K, Obayashi T, Hayashi T, Takeuchi T, Cell cycle regulation in mouse heart during embryonic and postnatal stages. Dev Growth Differ. 2012 Oct;54(8):731-8 |
2 | J:201110 Komada M, Iguchi T, Takeda T, Ishibashi M, Sato M, Smoothened controls cyclin D2 expression and regulates the generation of intermediate progenitors in the developing cortex. Neurosci Lett. 2013 Jun 28;547:87-91 |
1 | J:166777 Lavado A, Lagutin OV, Chow LM, Baker SJ, Oliver G, Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. PLoS Biol. 2010;8(8) |
1* | J:294282 Li L, Ruan X, Wen C, Chen P, Liu W, Zhu L, Xiang P, Zhang X, Wei Q, Hou L, Yin B, Yuan J, Qiang B, Shu P, Peng X, The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019 Jul 16;28(3):698-711.e5 |
1 | J:171254 Matsumoto A, Onoyama I, Sunabori T, Kageyama R, Okano H, Nakayama KI, Fbxw7-dependent Degradation of Notch Is Required for Control of 'Stemness' and Neuronal-Glial Differentiation in Neural Stem Cells. J Biol Chem. 2011 Apr 15;286(15):13754-64 |
1* | J:182715 Monahan P, Himes AD, Parfieniuk A, Raetzman LT, p21, an important mediator of quiescence during pituitary tumor formation, is dispensable for normal pituitary development during embryogenesis. Mech Dev. 2012 Jan-Feb;128(11-12):640-52 |
1 | J:178882 Odajima J, Wills ZP, Ndassa YM, Terunuma M, Kretschmannova K, Deeb TZ, Geng Y, Gawrzak S, Quadros IM, Newman J, Das M, Jecrois ME, Yu Q, Li N, Bienvenu F, Moss SJ, Greenberg ME, Marto JA, Sicinski P, Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation. Dev Cell. 2011 Oct 18;21(4):655-68 |
1 | J:48539 Sunters A, McCluskey J, Grigoriadis AE, Control of cell cycle gene expression in bone development and during c-Fos-induced osteosarcoma formation. Dev Genet. 1998;22(4):386-97 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Ccne2 cyclin E2 | |
Results | Reference |
1 | J:166777 Lavado A, Lagutin OV, Chow LM, Baker SJ, Oliver G, Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. PLoS Biol. 2010;8(8) |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
Ccng1 cyclin G1 (Synonyms: cyclin G) | |
Results | Reference |
1 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
Ccno cyclin O (Synonyms: Ccnu, Ung2) | |
Results | Reference |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
1* | J:358447 Wang L, Gao L, Chen Y, Xu B, Transcriptional regulation of CCNO during the formation of multiple motile cilia. Biochem Biophys Res Commun. 2024 Nov 26;735:150428 |
Ccp110 centriolar coiled coil protein 110 (Synonyms: 6330503K22Rik, CP110) | |
Results | Reference |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
Ccpg1 cell cycle progression 1 (Synonyms: 1700030B06Rik, 1810073J13Rik, 9430028F23Rik, D9Ertd392e) | |
Results | Reference |
1* | J:120114 Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY, A biphasic pattern of gene expression during mouse retina development. BMC Dev Biol. 2006;6:48 |
Ccr2 C-C motif chemokine receptor 2 (Synonyms: CC-CKR-2, CCR2A, CCR2B, CKR2, CKR2A, CKR2B, Cmkbr2) | |
Results | Reference |
1 | J:257184 Leid J, Carrelha J, Boukarabila H, Epelman S, Jacobsen SE, Lavine KJ, Primitive Embryonic Macrophages are Required for Coronary Development and Maturation. Circ Res. 2016 May 13;118(10):1498-511 |
Ccr4 C-C motif chemokine receptor 4 (Synonyms: CC CKR-4, Cmkbr4) | |
Results | Reference |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
Cd3e CD3 antigen, epsilon polypeptide (Synonyms: CD3, CD3epsilon, T3e) | |
Results | Reference |
1* | J:58554 Dear TN, Boehm T, Diverse mRNA expression patterns of the mouse calpain genes Capn5, Capn6 and Capn11 during development. Mech Dev. 1999 Dec;89(1-2):201-9 |
1 | J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47 |
Cd4 CD4 antigen (Synonyms: L3T4, Ly-4) | |
Results | Reference |
1 | J:159868 Benezech C, White A, Mader E, Serre K, Parnell S, Pfeffer K, Ware CF, Anderson G, Caamano JH, Ontogeny of stromal organizer cells during lymph node development. J Immunol. 2010 Apr 15;184(8):4521-30 |
2 | J:269938 Bovay E, Sabine A, Prat-Luri B, Kim S, Son K, Willrodt AH, Olsson C, Halin C, Kiefer F, Betsholtz C, Jeon NL, Luther SA, Petrova TV, Multiple roles of lymphatic vessels in peripheral lymph node development. J Exp Med. 2018 Nov 5;215(11):2760-2777 |
1 | J:87395 Eberl G, Marmon S, Sunshine MJ, Rennert PD, Choi Y, Littman DR, An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat Immunol. 2004 Jan;5(1):64-73 |
1* | J:67917 Honda K, Nakano H, Yoshida H, Nishikawa S, Rennert P, Ikuta K, Tamechika M, Yamaguchi K, Fukumoto T, Chiba T, Nishikawa SI, Molecular basis for hematopoietic/mesenchymal interaction during initiation of peyer's patch organogenesis. J Exp Med. 2001 Mar 5;193(5):621-30 |
1 | J:336858 Vallecillo-Garcia P, Orgeur M, Comai G, Poehle-Kronnawitter S, Fischer C, Gloger M, Dumas CE, Giesecke-Thiel C, Sauer S, Tajbakhsh S, Hopken UE, Stricker S, A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation. Immunity. 2023 Jun 13;56(6):1204-1219.e8 |
1 | J:157747 van de Pavert SA, Olivier BJ, Goverse G, Vondenhoff MF, Greuter M, Beke P, Kusser K, Hopken UE, Lipp M, Niederreither K, Blomhoff R, Sitnik K, Agace WW, Randall TD, de Jonge WJ, Mebius RE, Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation. Nat Immunol. 2009 Nov;10(11):1193-9 |
1 | J:120816 Veiga-Fernandes H, Coles MC, Foster KE, Patel A, Williams A, Natarajan D, Barlow A, Pachnis V, Kioussis D, Tyrosine kinase receptor RET is a key regulator of Peyer's patch organogenesis. Nature. 2007 Mar 29;446(7135):547-51 |
1 | J:137812 Vondenhoff MF, Desanti GE, Cupedo T, Bertrand JY, Cumano A, Kraal G, Mebius RE, Golub R, Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner. J Leukoc Biol. 2008 Jul;84(1):152-61 |
1 | J:150308 Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009 May 1;182(9):5439-45 |
1 | J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34 |
Cd14 CD14 antigen | |
Results | Reference |
1 | J:340406 Lai Y, Guo Y, Liao C, Mao C, Liu J, Ren C, Yang W, Luo L, Chen W, Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development. Sci Rep. 2023 Sep 13;13(1):15170 |
Cd19 CD19 antigen | |
Results | Reference |
1 | J:137872 Suzuki K, Tanaka M, Watanabe N, Saito S, Nonaka H, Miyajima A, p75 Neurotrophin receptor is a marker for precursors of stellate cells and portal fibroblasts in mouse fetal liver. Gastroenterology. 2008 Jul;135(1):270-281.e3 |
Cd24a CD24a antigen (Synonyms: cluster of differentiation 24, heat stable antigen, HSA, Ly-52, nectadrin) | |
Results | Reference |
1 | J:34238 Calaora V, Chazal G, Nielsen PJ, Rougon G, Moreau H, mCD24 expression in the developing mouse brain and in zones of secondary neurogenesis in the adult. Neuroscience. 1996 Jul;73(2):581-94 |
1 | J:55511 Cram DS, McIntosh A, Oxbrow L, Johnston AM, DeAizpurua HJ, Differential mRNA display analysis of two related but functionally distinct rat insulinoma (RIN) cell lines: identification of CD24 and its expression in the developing pancreas. Differentiation. 1999 May;64(4):237-46 |
1* | J:59927 Guerriero A, Langmuir PB, Spain LM, Scott EW, PU.1 is required for myeloid-derived but not lymphoid-derived dendritic cells. Blood. 2000 Feb 1;95(3):879-85 |
Cd34 CD34 antigen | |
Results | Reference |
1 | J:66277 Beauchamp JR, Heslop L, Yu DS, Tajbakhsh S, Kelly RG, Wernig A, Buckingham ME, Partridge TA, Zammit PS, Expression of CD34 and myf5 defines the majority of quiescent adult skeletal muscle satellite cells. J Cell Biol. 2000 Dec 11;151(6):1221-34 |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:332508 Gao M, Liu X, Guo P, Wang J, Li J, Wang W, Stoddart MJ, Grad S, Li Z, Wu H, Li B, He Z, Zhou G, Liu S, Zhu W, Chen D, Zou X, Zhou Z, Deciphering postnatal limb development at single-cell resolution. iScience. 2023 Jan 20;26(1):105808 |
1 | J:299239 Qin X, Jiang Q, Nagano K, Moriishi T, Miyazaki T, Komori H, Ito K, Mark KV, Sakane C, Kaneko H, Komori T, Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts. PLoS Genet. 2020 Nov;16(11):e1009169 |
1 | J:338451 Shintani A, Fukai S, Nobusawa R, Taniguchi K, Hatatani T, Nagai H, Sakai T, Yoshimura T, Miyasaka M, Hayasaka H, Dach1 transcription factor regulates the expression of peripheral node addressin and lymphocyte trafficking in lymph nodes. Curr Res Immunol. 2022;3:175-185 |
1 | J:222173 Solano ME, Kowal MK, O'Rourke GE, Horst AK, Modest K, Plosch T, Barikbin R, Remus CC, Berger RG, Jago C, Ho H, Sass G, Parker VJ, Lydon JP, DeMayo FJ, Hecher K, Karimi K, Arck PC, Progesterone and HMOX-1 promote fetal growth by CD8+ T cell modulation. J Clin Invest. 2015 Apr;125(4):1726-38 |
1 | J:239521 Stzepourginski I, Nigro G, Jacob JM, Dulauroy S, Sansonetti PJ, Eberl G, Peduto L, CD34+ mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E506-E513 |
1* | J:231834 Vanhoutteghem A, Delhomme B, Herve F, Nondier I, Petit JM, Araki M, Araki K, Djian P, The importance of basonuclin 2 in adult mice and its relation to basonuclin 1. Mech Dev. 2016 May;140:53-73 |
1 | J:247907 Yao J, Guihard PJ, Wu X, Blazquez-Medela AM, Spencer MJ, Jumabay M, Tontonoz P, Fogelman AM, Bostrom KI, Yao Y, Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. J Cell Biol. 2017 Oct 02;216(10):3369-3385 |
Cd44 CD44 antigen (Synonyms: HERMES, Ly-24, Pgp-1) | |
Results | Reference |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1 | J:157519 Desai VD, Wang Y, Simirskii VN, Duncan MK, CD44 expression is developmentally regulated in the mouse lens and increases in the lens epithelium after injury. Differentiation. 2010 Feb;79(2):111-9 |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:144651 Farkas LM, Haffner C, Giger T, Khaitovich P, Nowick K, Birchmeier C, Paabo S, Huttner WB, Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex. Neuron. 2008 Oct 9;60(1):40-55 |
1 | J:283354 Guiu J, Hannezo E, Yui S, Demharter S, Ulyanchenko S, Maimets M, Jorgensen A, Perlman S, Lundvall L, Mamsen LS, Larsen A, Olesen RH, Andersen CY, Thuesen LL, Hare KJ, Pers TH, Khodosevich K, Simons BD, Jensen KB, Tracing the origin of adult intestinal stem cells. Nature. 2019 Jun;570(7759):107-111 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:347618 Qin T, So KKH, Hui CC, Sham MH, Ptch1 is essential for cochlear marginal cell differentiation and stria vascularis formation. Cell Rep. 2024 Apr 23;43(4):114083 |
1 | J:323119 Renauld JM, Khan V, Basch ML, Intermediate Cells of Dual Embryonic Origin Follow a Basal to Apical Gradient of Ingression Into the Lateral Wall of the Cochlea. Front Cell Dev Biol. 2022;10:867153 |
1* | J:18156 Sretavan DW, Feng L, Pure E, Reichardt LF, Embryonic neurons of the developing optic chiasm express L1 and CD44, cell surface molecules with opposing effects on retinal axon growth. Neuron. 1994 May;12(5):957-75 |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
1 | J:356826 Wuelling M, Neu C, Thiesen AM, Kitanovski S, Cao Y, Lange A, Westendorf AM, Hoffmann D, Vortkamp A, Epigenetic Mechanisms Mediating Cell State Transitions in Chondrocytes. J Bone Miner Res. 2021 May;36(5):968-985 |
Cd63 CD63 antigen (Synonyms: ME491, Tspan30) | |
Results | Reference |
1* | J:297164 Nie X, Zheng J, Cruciger M, Yang P, Mao JJ, mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev Biol. 2020 Nov 1;467(1-2):77-87 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Cd68 CD68 antigen (Synonyms: gp110, Lamp4, macrosialin, Scard1) | |
Results | Reference |
1 | J:273194 Anderson SR, Zhang J, Steele MR, Romero CO, Kautzman AG, Schafer DP, Vetter ML, Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia. J Neurosci. 2019 Mar 13;39(11):2025-2040 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:257184 Leid J, Carrelha J, Boukarabila H, Epelman S, Jacobsen SE, Lavine KJ, Primitive Embryonic Macrophages are Required for Coronary Development and Maturation. Circ Res. 2016 May 13;118(10):1498-511 |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1 | J:339241 Liu, K., Intercellular genetic tracing of cardiac endothelium in the developing heart. Dev Cell. 2023 Aug 21;58(16):1502-1512 |
1 | J:231970 Stevens SM, Gise Av, VanDusen N, Zhou B, Pu WT, Epicardium is required for cardiac seeding by yolk sac macrophages, precursors of resident macrophages of the adult heart. Dev Biol. 2016 May 15;413(2):153-9 |
1* | J:282278 Zhou Y, Bennett TM, Shiels A, A charged multivesicular body protein (CHMP4B) is required for lens growth and differentiation. Differentiation. 2019 Sep - Oct;109:16-27 |
Cd74 CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated) (Synonyms: CLIP, Ii) | |
Results | Reference |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
Cd79a CD79A antigen (immunoglobulin-associated alpha) (Synonyms: Cd79a, Iga, Ig alpha, Ig-alpha, Igalpha, Ly-54, Ly54, mb-1) | |
Results | Reference |
1 | J:332498 Tran Nguyen Truc L, Matsuda S, Takenouchi A, Tran Thuy Huong Q, Kotani Y, Miyazaki T, Kanda H, Yoshizawa K, Tsukaguchi H, Mechanism of cystogenesis by Cd79a-driven, conditional mTOR activation in developing mouse nephrons. Sci Rep. 2023 Jan 10;13(1):508 |
Cd81 CD81 antigen (Synonyms: Tapa-1, Tapa1, Tspan28) | |
Results | Reference |
1* | J:2032 Andria ML, Barsh GS, Levy S, Expression of TAPA-1 in preimplantation mouse embryos. Biochem Biophys Res Commun. 1992 Aug 14;186(3):1201-6 |
Cd86 CD86 antigen (Synonyms: B70, B7-2, B7.2, Cd28l2, Ly-58, Ly58, MB7-2) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Cd109 CD109 antigen (Synonyms: 9930012E15Rik, Gov platelet alloantigens) | |
Results | Reference |
1 | J:342844 Harvey AB, Wolters RA, Deepe RN, Tarolli HG, Drummond JR, Trouten A, Zandi A, Barth JL, Mukherjee R, Romeo MJ, Vaena SG, Tao G, Muise-Helmericks R, Ramos PS, Norris RA, Wessels A, Epicardial deletion of Sox9 leads to myxomatous valve degeneration and identifies Cd109 as a novel gene associated with valve development. J Mol Cell Cardiol. 2023 Nov 5;186:16-30 |
Cd248 CD248 antigen, endosialin (Synonyms: 2610111G01Rik, Cd164l1, Tem1) | |
Results | Reference |
1* | J:171497 Huang HP, Hong CL, Kao CY, Lin SW, Lin SR, Wu HL, Shi GY, You LR, Wu CL, Yu IS, Gene targeting and expression analysis of mouse Tem1/endosialin using a lacZ reporter. Gene Expr Patterns. 2011 Jun-Jul;11(5-6):316-26 |
Cd320 CD320 antigen (Synonyms: 425O18-1, 8D6, D17Ertd716e, NG29, TCblR, VLDL) | |
Results | Reference |
1* | J:199961 Lai SC, Nakayama Y, Sequeira JM, Wlodarczyk BJ, Cabrera RM, Finnell RH, Bottiglieri T, Quadros EV, The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system. FASEB J. 2013 Jun;27(6):2468-75 |
Cdc20 cell division cycle 20 (Synonyms: 2310042N09Rik, p55CDC) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
1 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Cdc25a cell division cycle 25A (Synonyms: D9Ertd393e) | |
Results | Reference |
1* | J:26754 Wickramasinghe D, Becker S, Ernst MK, Resnick JL, Centanni JM, Tessarollo L, Grabel LB, Donovan PJ, Two CDC25 homologues are differentially expressed during mouse development. Development. 1995 Jul;121(7):2047-56 |
Cdc25b cell division cycle 25B | |
Results | Reference |
1 | J:353313 Roussat M, Jungas T, Audouard C, Omerani S, Medevielle F, Agius E, Davy A, Pituello F, Bel-Vialar S, Control of G(2) Phase Duration by CDC25B Modulates the Switch from Direct to Indirect Neurogenesis in the Neocortex. J Neurosci. 2023 Feb 15;43(7):1154-1165 |
Cdc25c cell division cycle 25C (Synonyms: Cdc25) | |
Results | Reference |
1 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
1* | J:26789 Wu S, Wolgemuth DJ, The distinct and developmentally regulated patterns of expression of members of the mouse Cdc25 gene family suggest differential functions during gametogenesis. Dev Biol. 1995 Jul;170(1):195-206 |
1* | J:332876 Zhou X, Lu D, Yi W, Xu D, Downregulation of CDC25C in NPCs Disturbed Cortical Neurogenesis. Int J Mol Sci. 2023 Jan 12;24(2) |
Cdc42 cell division cycle 42 | |
Results | Reference |
1 | J:79013 Hayashi K, Ohshima T, Mikoshiba K, Pak1 is involved in dendrite initiation as a downstream effector of rac1 in cortical neurons. Mol Cell Neurosci. 2002 Aug;20(4):579 |
1 | J:167714 Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, Chen H, Haneline LS, Chan RJ, Schwartz RJ, Field LJ, Atkinson SJ, Shou W, Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development. 2011 Jan;138(2):303-15 |
1 | J:197886 Peng X, Lin Q, Liu Y, Jin Y, Druso JE, Antonyak MA, Guan JL, Cerione RA, Inactivation of Cdc42 in embryonic brain results in hydrocephalus with ependymal cell defects in mice. Protein Cell. 2013 Mar;4(3):231-42 |
1 | J:316121 Wang JR, Wang CJ, Xu CY, Wu XK, Hong D, Shi W, Gong Y, Chen HX, Long F, Wu XM, Signaling Cascades Governing Cdc42-Mediated Chondrogenic Differentiation and Mensenchymal Condensation. Genetics. 2016 Mar;202(3):1055-69 |
Cdc42ep1 CDC42 effector protein 1 (Synonyms: 1810058K22Rik, Borg5, CEP1, MSE55) | |
Results | Reference |
1 | J:310382 Liu Z, Vong QP, Liu C, Zheng Y, Borg5 is required for angiogenesis by regulating persistent directional migration of the cardiac microvascular endothelial cells. Mol Biol Cell. 2014 Mar;25(6):841-51 |
Cdc45 cell division cycle 45 (Synonyms: Cdc45l) | |
Results | Reference |
1* | J:53820 Shaikh TH, Gottlieb S, Sellinger B, Chen F, Roe BA, Oakey RJ, Emanuel BS, Budarf ML, Characterization of CDC45L: a gene in the 22q11.2 deletion region expressed during murine and human development. Mamm Genome. 1999 Mar;10(3):322-6 |
Cdc73 cell division cycle 73, Paf1/RNA polymerase II complex component (Synonyms: 8430414L16Rik, C130030P16Rik, Hrpt2, MGC:29274, MGC:36559) | |
Results | Reference |
1* | J:135255 Wang P, Bowl MR, Bender S, Peng J, Farber L, Chen J, Ali A, Zhang Z, Alberts AS, Thakker RV, Shilatifard A, Williams BO, Teh BT, Parafibromin, a component of the human PAF complex, regulates growth factors and is required for embryonic development and survival in adult mice. Mol Cell Biol. 2008 May;28(9):2930-40 |
Cdca7 cell division cycle associated 7 (Synonyms: 2310021G01Rik, JPO1) | |
Results | Reference |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
Cdh1 cadherin 1 (Synonyms: E-cad, Ecad, E-cadherin, L-CAM, UM, uvomorulin) | |
Results | Reference |
1 | J:359451 Amato CM, Xu X, Yao HH, An extragenital cell population contributes to urethra closure during mouse penis development. Sci Adv. 2024 Dec 6;10(49):eadp0673 |
1 | J:321578 Ang PS, Matrongolo MJ, Tischfield MA, The growth and expansion of meningeal lymphatic networks are affected in craniosynostosis. Development. 2022 Jan 1;149(1):dev200065 |
1* | J:69761 Angres B, Kim L, Jung R, Gessner R, Tauber R, LI-cadherin gene expression during mouse intestinal development. Dev Dyn. 2001 Jun;221(2):182-93 |
1 | J:150973 Antoniou A, Raynaud P, Cordi S, Zong Y, Tronche F, Stanger BZ, Jacquemin P, Pierreux CE, Clotman F, Lemaigre FP, Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology. 2009 Jun;136(7):2325-33 |
1 | J:228518 Arya P, Rainey MA, Bhattacharyya S, Mohapatra BC, George M, Kuracha MR, Storck MD, Band V, Govindarajan V, Band H, The endocytic recycling regulatory protein EHD1 Is required for ocular lens development. Dev Biol. 2015 Dec 1;408(1):41-55 |
1 | J:341713 Aure MH, Symonds JM, Villapudua CU, Dodge JT, Werner S, Knosp WM, Hoffman MP, FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation. Nat Commun. 2023 Oct 14;14(1):6485 |
1 | J:346910 Ayyangar U, Karkhanis A, Tay H, Afandi AFB, Bhattacharjee O, Ks L, Lee SH, Chan J, Raghavan S, Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin. EMBO J. 2024 Apr;43(7):1113-1134 |
1 | J:226938 Bagherie-Lachidan M, Reginensi A, Pan Q, Zaveri HP, Scott DA, Blencowe BJ, Helmbacher F, McNeill H, Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool. Development. 2015 Aug 1;142(15):2564-73 |
1 | J:263981 Benhamouche-Trouillet S, O'Loughlin E, Liu CH, Polacheck W, Fitamant J, McKee M, El-Bardeesy N, Chen CS, McClatchey AI, Proliferation-independent role of NF2 (merlin) in limiting biliary morphogenesis. Development. 2018 Apr 30;145(9):dev162123 |
1* | J:306328 Bhattarai SR, Begum S, Popow R, Ezratty EJ, The ciliary GTPase Arl3 maintains tissue architecture by directing planar spindle orientation during epidermal morphogenesis. Development. 2019 May 10;146(9):dev161885 |
1 | J:106993 Briancon N, Weiss MC, In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping. EMBO J. 2006 Mar 22;25(6):1253-62 |
1 | J:331471 Brownfield DG, de Arce AD, Ghelfi E, Gillich A, Desai TJ, Krasnow MA, Alveolar cell fate selection and lifelong maintenance of AT2 cells by FGF signaling. Nat Commun. 2022 Nov 21;13(1):7137 |
1 | J:307544 Burtscher I, Tarquis-Medina M, Salinno C, Schirge S, Beckenbauer J, Bakhti M, Lickert H, Generation of a Novel Nkx6-1 Venus Fusion Reporter Mouse Line. Int J Mol Sci. 2021 Mar 26;22(7) |
2 | J:235730 Byrd KM, Lough KJ, Patel JH, Descovich CP, Curtis TA, Williams SE, LGN plays distinct roles in oral epithelial stratification, filiform papilla morphogenesis and hair follicle development. Development. 2016 Aug 1;143(15):2803-17 |
1 | J:196836 Cammas L, Wolfe J, Choi SY, Dedhar S, Beggs HE, Integrin-linked kinase deletion in the developing lens leads to capsule rupture, impaired fiber migration and non-apoptotic epithelial cell death. Invest Ophthalmol Vis Sci. 2012;53(6):3067-81 |
1 | J:177402 Carpentier R, Suner RE, van Hul N, Kopp JL, Beaudry JB, Cordi S, Antoniou A, Raynaud P, Lepreux S, Jacquemin P, Leclercq IA, Sander M, Lemaigre FP, Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells. Gastroenterology. 2011 Oct;141(4):1432-1438.e4 |
2 | J:192176 Casanova JC, Travisano S, de la Pompa JL, Epithelial-to-mesenchymal transition in epicardium is independent of snail1. Genesis. 2013 Jan;51(1):32-40 |
2 | J:202949 Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J, Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18042-51 |
1 | J:194489 Chen SR, Chen M, Wang XN, Zhang J, Wen Q, Ji SY, Zheng QS, Gao F, Liu YX, The wilms tumor gene, wt1, maintains testicular cord integrity by regulating the expression of col4a1 and col4a2. Biol Reprod. 2013;88(3):56 |
1 | J:223109 Choi JJ, Ting CT, Trogrlic L, Milevski SV, Familari M, Martinez G, de Iongh RU, A role for smoothened during murine lens and cornea development. PLoS One. 2014;9(9):e108037 |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1 | J:272608 Cohen I, Zhao D, Menon G, Nakayama M, Koseki H, Zheng D, Ezhkova E, PRC1 preserves epidermal tissue integrity independently of PRC2. Genes Dev. 2019 Jan 1;33(1-2):55-60 |
1* | J:332642 Cohen-Gulkar M, David A, Messika-Gold N, Eshel M, Ovadia S, Zuk-Bar N, Idelson M, Cohen-Tayar Y, Reubinoff B, Ziv T, Shamay M, Elkon R, Ashery-Padan R, The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration. PLoS Biol. 2023 Jan;21(1):e3001924 |
1 | J:283675 Comai G, Heude E, Mella S, Paisant S, Pala F, Gallardo M, Langa F, Kardon G, Gopalakrishnan S, Tajbakhsh S, A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle. Elife. 2019 Sep 19;8:e47460 |
1 | J:167041 Cook MS, Munger SC, Nadeau JH, Capel B, Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background. Development. 2011 Jan;138(1):23-32 |
1* | J:291486 Daniel E, Barlow HR, Sutton GI, Gu X, Htike Y, Cowdin MA, Cleaver O, Cyp26b1 is an essential regulator of distal airway epithelial differentiation during lung development. Development. 2020 Feb 20;147(4):dev181560 |
1 | J:119857 Desmots F, Russell HR, Lee Y, Boyd K, McKinnon PJ, The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development. Mol Cell Biol. 2005 Dec;25(23):10329-37 |
1 | J:145627 Devenport D, Fuchs E, Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol. 2008 Nov;10(11):1257-68 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1 | J:242729 Ding X, Bloch W, Iden S, Ruegg MA, Hall MN, Leptin M, Partridge L, Eming SA, mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation. Nat Commun. 2016 Oct 27;7:13226 |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82 |
1 | J:316977 Endale M, Ahlfeld S, Bao E, Chen X, Green J, Bess Z, Weirauch MT, Xu Y, Perl AK, Temporal, spatial, and phenotypical changes of PDGFRalpha expressing fibroblasts during late lung development. Dev Biol. 2017 May 15;425(2):161-175 |
1 | J:267596 Escot S, Willnow D, Naumann H, Di Francescantonio S, Spagnoli FM, Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors. Nat Commun. 2018 Nov 30;9(1):5082 |
1 | J:132812 Fauquier T, Rizzoti K, Dattani M, Lovell-Badge R, Robinson IC, SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2907-12 |
1* | J:47740 Fausser JL, Schlepp O, Aberdam D, Meneguzzi G, Ruch JV, Lesot H, Localization of antigens associated with adherens junctions, desmosomes, and hemidesmosomes during murine molar morphogenesis. Differentiation. 1998 May;63(1):1-11 |
1 | J:226950 Fogelgren B, Polgar N, Lui VH, Lee AJ, Tamashiro KK, Napoli JA, Walton CB, Zuo X, Lipschutz JH, Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions. PLoS One. 2015;10(6):e0129346 |
1 | J:339855 Gannoun L, De Schrevel C, Belle M, Dauguet N, Achouri Y, Loriot A, Vanderaa C, Cordi S, Dili A, Heremans Y, Rooman I, Leclercq IA, Jacquemin P, Gatto L, Lemaigre FP, Axon guidance genes control hepatic artery development. Development. 2023 Aug 15;150(16):dev201642 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:192856 George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE, Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol. 2012 Dec;32(24):5116-28 |
1* | J:317799 Gervais EM, Sequeira SJ, Wang W, Abraham S, Kim JH, Leonard D, DeSantis KA, Larsen M, Par-1b is required for morphogenesis and differentiation of myoepithelial cells during salivary gland development. Organogenesis. 2016 Oct;12(4):194-216 |
1 | J:316093 Golden EJ, Larson ED, Shechtman LA, Trahan GD, Gaillard D, Fellin TJ, Scott JK, Jones KL, Barlow LA, Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function. Elife. 2021 May 19;10:e64013 |
1 | J:178336 Grosse AS, Pressprich MF, Curley LB, Hamilton KL, Margolis B, Hildebrand JD, Gumucio DL, Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis. Development. 2011 Oct;138(20):4423-32 |
2 | J:283354 Guiu J, Hannezo E, Yui S, Demharter S, Ulyanchenko S, Maimets M, Jorgensen A, Perlman S, Lundvall L, Mamsen LS, Larsen A, Olesen RH, Andersen CY, Thuesen LL, Hare KJ, Pers TH, Khodosevich K, Simons BD, Jensen KB, Tracing the origin of adult intestinal stem cells. Nature. 2019 Jun;570(7759):107-111 |
1 | J:301041 Guo D, Ru J, Mao F, Ouyang H, Ju R, Wu K, Liu Y, Liu C, Ontogenesis of the tear drainage system requires Prickle1-driven polarized basement membrane deposition. Development. 2020 Nov 30;147(22):dev191726 |
1 | J:222425 Harada M, Omori A, Nakahara C, Nakagata N, Akita K, Yamada G, Tissue-specific roles of FGF signaling in external genitalia development. Dev Dyn. 2015 Jun;244(6):759-73 |
1* | J:348284 Hassan D, Chen J, CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair. Nat Commun. 2024 May 16;15(1):4148 |
1* | J:238590 Hayashi K, Ikari T, Sugiyama G, Sugiura T, Ohyama Y, Kumamaru W, Shirasuna K, Mori Y, Involvement of the T-box transcription factor Brachyury in early-stage embryonic mouse salivary gland. Biochem Biophys Res Commun. 2016 Sep 02;477(4):814-9 |
1 | J:326201 Hayashi T, Eto K, Kadoya Y, Downregulation of ten-eleven translocation-2 triggers epithelial differentiation during organogenesis. Differentiation. 2022 May-Jun;125:45-53 |
1 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:219824 Hendley AM, Provost E, Bailey JM, Wang YJ, Cleveland MH, Blake D, Bittman RW, Roeser JC, Maitra A, Reynolds AB, Leach SD, p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas. Dev Biol. 2015 Mar 1;399(1):41-53 |
1 | J:200722 Hick AC, Delmarcelle AS, Bouquet M, Klotz S, Copetti T, Forez C, Van Der Smissen P, Sonveaux P, Collet JF, Feron O, Courtoy PJ, Pierreux CE, Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiation. Dev Biol. 2013 Sep 1;381(1):227-40 |
1* | J:156021 Hick AC, van Eyll JM, Cordi S, Forez C, Passante L, Kohara H, Nagasawa T, Vanderhaeghen P, Courtoy PJ, Rousseau GG, Lemaigre FP, Pierreux CE, Mechanism of primitive duct formation in the pancreas and submandibular glands: a role for SDF-1. BMC Dev Biol. 2009;9:66 |
1 | J:300508 Hilliard SA, Li Y, Dixon A, El-Dahr SS, Mdm4 controls ureteric bud branching via regulation of p53 activity. Mech Dev. 2020 Sep;163:103616 |
1* | J:207609 Hilliard SA, Yao X, El-Dahr SS, Mdm2 is required for maintenance of the nephrogenic niche. Dev Biol. 2014 Mar 1;387(1):1-14 |
1 | J:31205 Hirai Y, Nose A, Kobayashi S, Takeichi M, Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis. II. Skin morphogenesis. Development. 1989 Feb;105(2):271-7 |
1 | J:166890 Hofmann JJ, Zovein AC, Koh H, Radtke F, Weinmaster G, Iruela-Arispe ML, Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome. Development. 2010 Dec;137(23):4061-72 |
1 | J:28082 Holmberg M, Leonardsson G, Ny T, The species-specific differences in the cAMP regulation of the tissue-type plasminogen activator gene between rat, mouse and human is caused by a one-nucleotide substitution in the cAMP-responsive element of the promoters. Eur J Biochem. 1995 Jul 15;231(2):466-74 |
1 | J:239651 Hurtado R, Zewdu R, Mtui J, Liang C, Aho R, Kurylo C, Selleri L, Herzlinger D, Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning. Development. 2015 Aug 01;142(15):2653-64 |
1 | J:349163 Huycke TR, Hakkinen TJ, Miyazaki H, Srivastava V, Barruet E, McGinnis CS, Kalantari A, Cornwall-Scoones J, Vaka D, Zhu Q, Jo H, Oria R, Weaver VM, DeGrado WF, Thomson M, Garikipati K, Boffelli D, Klein OD, Gartner ZJ, Patterning and folding of intestinal villi by active mesenchymal dewetting. Cell. 2024 Jun 6;187(12):3072-3089.e20 |
1 | J:291050 Ide S, Finer G, Maezawa Y, Onay T, Souma T, Scott R, Ide K, Akimoto Y, Li C, Ye M, Zhao X, Baba Y, Minamizuka T, Jin J, Takemoto M, Yokote K, Quaggin SE, Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development. J Am Soc Nephrol. 2018 Dec;29(12):2795-2808 |
1 | J:197573 Itoh Y, Moriyama Y, Hasegawa T, Endo TA, Toyoda T, Gotoh Y, Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition-like mechanism. Nat Neurosci. 2013 Apr;16(4):416-25 |
1 | J:188056 Jameson SA, Lin YT, Capel B, Testis development requires the repression of Wnt4 by Fgf signaling. Dev Biol. 2012 Oct 1;370(1):24-32 |
2* | J:82378 Jamora C, DasGupta R, Kocieniewski P, Fuchs E, Links between signal transduction, transcription and adhesion in epithelial bud development. Nature. 2003 Mar 20;422(6929):317-22 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:304850 Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernandez-Baldovinos J, Zhou L, Hoss C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Grone HJ, Graumann PL, Niessen CM, Offermanns S, Wickstrom SA, Worzfeld T, Mechanochemical control of epidermal stem cell divisions by B-plexins. Nat Commun. 2021 Feb 26;12(1):1308 |
2 | J:173588 Kanazawa T, Ichii O, Otsuka S, Namiki Y, Hashimoto Y, Kon Y, Hepatocyte nuclear factor 4 alpha is associated with mesenchymal-epithelial transition in developing kidneys of C57BL/6 mice. J Vet Med Sci. 2011 May;73(5):601-7 |
1 | J:154990 Kang HS, Kim YS, ZeRuth G, Beak JY, Gerrish K, Kilic G, Sosa-Pineda B, Jensen J, Foley J, Jetten AM, Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression. Mol Cell Biol. 2009 Dec;29(24):6366-79 |
2* | J:266596 Kersbergen A, Best SA, Dworkin S, Ah-Cann C, de Vries ME, Asselin-Labat ML, Ritchie ME, Jane SM, Sutherland KD, Lung morphogenesis is orchestrated through Grainyhead-like 2 (Grhl2) transcriptional programs. Dev Biol. 2018 Nov 1;443(1):1-9 |
1 | J:268349 Kim HT, Yin W, Jin YJ, Panza P, Gunawan F, Grohmann B, Buettner C, Sokol AM, Preussner J, Guenther S, Kostin S, Ruppert C, Bhagwat AM, Ma X, Graumann J, Looso M, Guenther A, Adelstein RS, Offermanns S, Stainier DYR, Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease. Nat Commun. 2018 Nov 2;9(1):4600 |
1 | J:282804 Kim HT, Yin W, Nakamichi Y, Panza P, Grohmann B, Buettner C, Guenther S, Ruppert C, Kobayashi Y, Guenther A, Stainier DYR, WNT/RYK signaling restricts goblet cell differentiation during lung development and repair. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25697-25706 |
1 | J:266265 Kishimoto K, Tamura M, Nishita M, Minami Y, Yamaoka A, Abe T, Shigeta M, Morimoto M, Synchronized mesenchymal cell polarization and differentiation shape the formation of the murine trachea and esophagus. Nat Commun. 2018 Jul 19;9(1):2816 |
1 | J:240472 Kumar N, Srivillibhuthur M, Joshi S, Walton KD, Zhou A, Faller WJ, Perekatt AO, Sansom OJ, Gumucio DL, Xing J, Bonder EM, Gao N, White E, Verzi MP, A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis. Development. 2016 Oct 15;143(20):3711-3722 |
2 | J:257613 Kuony A, Michon F, Epithelial Markers aSMA, Krt14, and Krt19 Unveil Elements of Murine Lacrimal Gland Morphogenesis and Maturation. Front Physiol. 2017;8:739 |
1* | J:316578 Lade A, Ranganathan S, Luo J, Monga SP, Calpain induces N-terminal truncation of beta-catenin in normal murine liver development: diagnostic implications in hepatoblastomas. J Biol Chem. 2012 Jun 29;287(27):22789-98 |
1 | J:332513 Laporte E, De Vriendt S, Hoekx J, Vankelecom H, Interleukin-6 is dispensable in pituitary normal development and homeostasis but needed for pituitary stem cell activation following local injury. Front Endocrinol (Lausanne). 2022;13:1092063 |
2 | J:237343 Laresgoiti U, Nikolic MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL, Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016 Oct 15;143(20):3686-3699 |
1* | J:250161 Lee AJ, Polgar N, Napoli JA, Lui VH, Tamashiro KK, Fujimoto BA, Thompson KS, Fogelgren B, Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy. Sci Rep. 2016 Aug 11;6:31137 |
1 | J:301558 Lee DH, Olson AW, Wang J, Kim WK, Mi J, Zeng H, Le V, Aldahl J, Hiroto A, Wu X, Sun Z, Androgen action in cell fate and communication during prostate development at single-cell resolution. Development. 2021 Jan 11;148(1):dev196048 |
1 | J:199510 Lee J, Andreeva A, Sipe CW, Liu L, Cheng A, Lu X, PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium. Curr Biol. 2012 Jun 5;22(11):956-66 |
1* | J:293624 Lee S, Sears MJ, Zhang Z, Li H, Salhab I, Krebs P, Xing Y, Nah HD, Williams T, Carstens RP, Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk. Development. 2020 Apr 30;147(21):dev187369 |
1 | J:264403 Li Q, Jiao J, Li H, Wan H, Zheng C, Cai J, Bao S, Histone arginine methylation by Prmt5 is required for lung branching morphogenesis through repression of BMP signaling. J Cell Sci. 2018 Jul 25;131(14):jcs217406 |
1 | J:189074 Li ZJ, Nieuwenhuis E, Nien W, Zhang X, Zhang J, Puviindran V, Wainwright BJ, Kim PC, Hui CC, Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis. Development. 2012 Nov;139(22):4152-61 |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1 | J:317416 Liu J, Qi Y, Chao J, Sathuvalli P, Y Lee L, Li S, CREG1 promotes lysosomal biogenesis and function. Autophagy. 2021 Dec;17(12):4249-4265 |
1* | J:131173 Liu Y, El-Naggar S, Darling DS, Higashi Y, Dean DC, Zeb1 links epithelial-mesenchymal transition and cellular senescence. Development. 2008 Feb;135(3):579-88 |
1 | J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134 |
1 | J:315454 Loscertales M, Nicolaou F, Jeanne M, Longoni M, Gould DB, Sun Y, Maalouf FI, Nagy N, Donahoe PK, Type IV collagen drives alveolar epithelial-endothelial association and the morphogenetic movements of septation. BMC Biol. 2016 Jul 13;14:59 |
1 | J:294113 Lough KJ, Byrd KM, Descovich CP, Spitzer DC, Bergman AJ, Beaudoin GM 3rd, Reichardt LF, Williams SE, Telophase correction refines division orientation in stratified epithelia. Elife. 2019 Dec 13;8:e49249 |
1* | J:346057 Lu D, Zhi Y, Su H, Lin X, Lin J, Shi Y, Yi W, Hong C, Zhang T, Fu Z, Chen LY, Zhao Z, Li R, Xu Z, Chen W, Wang N, Xu D, ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells. Cell Rep. 2024 Feb 24;43(3):113818 |
1 | J:91298 Lu X, Borchers AG, Jolicoeur C, Rayburn H, Baker JC, Tessier-Lavigne M, PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates. Nature. 2004 Jul 1;430(6995):93-8 |
1 | J:203797 Maatouk DM, Mork L, Chassot AA, Chaboissier MC, Capel B, Disruption of mitotic arrest precedes precocious differentiation and transdifferentiation of pregranulosa cells in the perinatal Wnt4 mutant ovary. Dev Biol. 2013 Nov 15;383(2):295-306 |
1 | J:321068 Maimets M, Pedersen MT, Guiu J, Dreier J, Thodberg M, Antoku Y, Schweiger PJ, Rib L, Bressan RB, Miao Y, Garcia KC, Sandelin A, Serup P, Jensen KB, Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling. Nat Commun. 2022 Feb 7;13(1):715 |
2 | J:207861 Manthey AL, Lachke SA, FitzGerald PG, Mason RW, Scheiblin DA, McDonald JH, Duncan MK, Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development. Mech Dev. 2014 Feb;131:86-110 |
1 | J:239657 Mao Y, Francis-West P, Irvine KD, Fat4/Dchs1 signaling between stromal and cap mesenchyme cells influences nephrogenesis and ureteric bud branching. Development. 2015 Aug 01;142(15):2574-85 |
1 | J:166573 Martinez-Estrada OM, Lettice LA, Essafi A, Guadix JA, Slight J, Velecela V, Hall E, Reichmann J, Devenney PS, Hohenstein P, Hosen N, Hill RE, Munoz-Chapuli R, Hastie ND, Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin. Nat Genet. 2010 Jan;42(1):89-93 |
1 | J:330583 McKey J, Anbarci DN, Bunce C, Ontiveros AE, Behringer RR, Capel B, Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii. Elife. 2022 Sep 27;11:e81088 |
1* | J:316269 Mehta V, Schmitz CT, Keil KP, Joshi PS, Abler LL, Lin TM, Taketo MM, Sun X, Vezina CM, Beta-catenin (CTNNB1) induces Bmp expression in urogenital sinus epithelium and participates in prostatic bud initiation and patterning. Dev Biol. 2013 Apr 15;376(2):125-35 |
1* | J:218202 Mellas RE, Kim H, Osinski J, Sadibasic S, Gronostajski RM, Cho M, Baker OJ, NFIB Regulates Embryonic Development of Submandibular Glands. J Dent Res. 2015 Feb;94(2):312-9 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1 | J:333797 Min KW, Kim N, Lee JH, Sung Y, Kim M, Lee EJ, Kim JM, Kim JH, Lee J, Cho W, Yang JM, Kim N, Kim J, Lee CJ, Park YG, Lee SH, Lee HW, Kim JW, Visuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant. Exp Mol Med. 2023 Feb;55(2):385-400 |
1 | J:352884 Miura A, Sarmah H, Tanaka J, Hwang Y, Sawada A, Shimamura Y, Otoshi T, Kondo Y, Fang Y, Shimizu D, Ninish Z, Suer JL, Dubois NC, Davis J, Toyooka S, Wu J, Que J, Hawkins FJ, Lin CS, Mori M, Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes the generation of the whole lung. Elife. 2023 Oct 20;12 |
1 | J:321073 Mollo MR, Antonini D, Mitchell K, Fortugno P, Costanzo A, Dixon J, Brancati F, Missero C, p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis. Exp Dermatol. 2015 Feb;24(2):114-9 |
1* | J:203768 Mustata RC, Vasile G, Fernandez-Vallone V, Strollo S, Lefort A, Libert F, Monteyne D, Perez-Morga D, Vassart G, Garcia MI, Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium. Cell Rep. 2013 Oct 31;5(2):421-32 |
2* | J:77927 Muto S, Aiba A, Saito Y, Nakao K, Nakamura K, Tomita K, Kitamura T, Kurabayashi M, Nagai R, Higashihara E, Harris PC, Katsuki M, Horie S, Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant. Hum Mol Genet. 2002 Jul 15;11(15):1731-42 |
1 | J:182928 Nagarajan P, Chin SS, Wang D, Liu S, Sinha S, Garrett-Sinha LA, Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators. J Cell Sci. 2010 Oct 15;123(Pt 20):3566-75 |
1* | J:132157 Nakamura T, de Vega S, Fukumoto S, Jimenez L, Unda F, Yamada Y, Transcription factor epiprofin is essential for tooth morphogenesis by regulating epithelial cell fate and tooth number. J Biol Chem. 2008 Feb 22;283(8):4825-33 |
1 | J:309402 Nakamura T, Jimenez-Rojo L, Koyama E, Pacifici M, de Vega S, Iwamoto M, Fukumoto S, Unda F, Yamada Y, Epiprofin Regulates Enamel Formation and Tooth Morphogenesis by Controlling Epithelial-Mesenchymal Interactions During Tooth Development. J Bone Miner Res. 2017 Mar;32(3):601-610 |
1 | J:120229 Narlis M, Grote D, Gaitan Y, Boualia SK, Bouchard M, Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney. J Am Soc Nephrol. 2007 Apr;18(4):1121-9 |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
1* | J:137610 Nimura M, Udagawa J, Otani H, Adrenocorticotropic hormone affects nonapoptotic cell death of undifferentiated germ cells in the fetal mouse testis: in vivo study by exo utero transplantation of corticotropic tumor cells into embryos. Congenit Anom (Kyoto). 2008 Jun;48(2):81-6 |
1 | J:58408 Nishimura EK, Yoshida H, Kunisada T, Nishikawa SI, Regulation of E- and P-cadherin expression correlated with melanocyte migration and diversification. Dev Biol. 1999 Nov 15;215(2):155-66 |
1 | J:253982 Norlin S, Parekh V, Edlund H, The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival. Development. 2018 Jan 3;145(1):dev154468 |
1 | J:284168 Nyeng P, Heilmann S, Lof-Ohlin ZM, Pettersson NF, Hermann FM, Reynolds AB, Semb H, p120ctn-Mediated Organ Patterning Precedes and Determines Pancreatic Progenitor Fate. Dev Cell. 2019 Apr 8;49(1):31-47.e9 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
1 | J:264647 O'Brien LL, Guo Q, Bahrami-Samani E, Park JS, Hasso SM, Lee YJ, Fang A, Kim AD, Guo J, Hong TM, Peterson KA, Lozanoff S, Raviram R, Ren B, Fogelgren B, Smith AD, Valouev A, McMahon AP, Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies. PLoS Genet. 2018 Jan;14(1):e1007181 |
1 | J:48599 Obara N, Suzuki Y, Nagai Y, Takeda M, Expression of E- and P-cadherin during tooth morphogenesis and cytodifferentiation of ameloblasts. Anat Embryol (Berl). 1998 Jun;197(6):469-75 |
1 | J:242339 Ohayon D, Garces A, Joly W, Soukkarieh C, Takagi T, Sabourin JC, Agius E, Darling DS, De Santa Barbara P, Higashi Y, Stolt CC, Hugnot JP, Richardson WD, Carroll P, Pattyn A, Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Cell Rep. 2016 Nov 01;17(6):1473-1481 |
1 | J:328944 Olbertova K, Hrckulak D, Kriz V, Jesionek W, Kubovciak J, Esner M, Korinek V, Buchtova M, Role of LGR5-positive mesenchymal cells in craniofacial development. Front Cell Dev Biol. 2022;10:810527 |
1 | J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461 |
1 | J:171374 Osorio KM, Lilja KC, Tumbar T, Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol. 2011 Apr 4;193(1):235-50 |
1 | J:353578 Paramore SV, Goodwin K, Fowler EW, Devenport D, Nelson CM, Mesenchymal Vangl1 and Vangl2 facilitate airway elongation and widening independently of the planar cell polarity complex. Development. 2024 Aug 15;151(16):dev202692 |
1 | J:348633 Paramore SV, Trenado-Yuste C, Sharan R, Nelson CM, Devenport D, Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation. Dev Cell. 2024 May 20;59(10):1302-1316.e5 |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
1* | J:89197 Patterson LT, Potter SS, Atlas of Hox gene expression in the developing kidney. Dev Dyn. 2004 Apr;229(4):771-9 |
1 | J:191071 Petzold KM, Naumann H, Spagnoli FM, Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas. Development. 2013 Jan 1;140(1):126-35 |
1 | J:197599 Pitetti JL, Calvel P, Romero Y, Conne B, Truong V, Papaioannou MD, Schaad O, Docquier M, Herrera PL, Wilhelm D, Nef S, Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice. PLoS Genet. 2013;9(1):e1003160 |
1 | J:146606 Pritchard C, Mecham B, Dumpit R, Coleman I, Bhattacharjee M, Chen Q, Sikes RA, Nelson PS, Conserved gene expression programs integrate mammalian prostate development and tumorigenesis. Cancer Res. 2009 Mar 1;69(5):1739-47 |
1* | J:258304 Pui HP, Saga Y, NANOS2 acts as an intrinsic regulator of gonocytes-to-spermatogonia transition in the murine testes. Mech Dev. 2018 Feb;149:27-40 |
2 | J:124218 Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan YN, Rakic P, Sestan N, Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci. 2007 Jul;10(7):819-27 |
1 | J:202984 Rockich BE, Hrycaj SM, Shih HP, Nagy MS, Ferguson MA, Kopp JL, Sander M, Wellik DM, Spence JR, Sox9 plays multiple roles in the lung epithelium during branching morphogenesis. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4456-64 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1 | J:298302 Ru J, Guo D, Fan J, Zhang J, Ju R, Ouyang H, Wei L, Liu Y, Liu C, Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis. Invest Ophthalmol Vis Sci. 2020 Nov 2;61(13):6 |
1 | J:256217 Rubsam M, Mertz AF, Kubo A, Marg S, Jungst C, Goranci-Buzhala G, Schauss AC, Horsley V, Dufresne ER, Moser M, Ziegler W, Amagai M, Wickstrom SA, Niessen CM, E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning. Nat Commun. 2017 Nov 1;8(1):1250 |
1 | J:266746 Rudkouskaya A, Welch I, Dagnino L, ILK modulates epithelial polarity and matrix formation in hair follicles. Mol Biol Cell. 2014 Mar;25(5):620-32 |
1* | J:280280 Rutledge EA, Parvez RK, Short KM, Smyth IM, McMahon AP, Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease. Dev Biol. 2019 Oct 15;454(2):156-169 |
1 | J:138247 Saburi S, Hester I, Fischer E, Pontoglio M, Eremina V, Gessler M, Quaggin SE, Harrison R, Mount R, McNeill H, Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nat Genet. 2008 Aug;40(8):1010-5 |
1* | J:146871 Sadakata H, Okazawa H, Sato T, Supriatna Y, Ohnishi H, Kusakari S, Murata Y, Ito T, Nishiyama U, Minegishi T, Harada A, Matozaki T, SAP-1 is a microvillus-specific protein tyrosine phosphatase that modulates intestinal tumorigenesis. Genes Cells. 2009 Mar;14(3):295-308 |
1 | J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356 |
1 | J:361603 Scavuzzo MA, Szlachcic WJ, Hill MC, Ziojla NM, Teaw J, Carlson JC, Tiessen J, Chmielowiec J, Martin JF, Borowiak M, Pancreatic organogenesis mapped through space and time. Exp Mol Med. 2025 Feb;57(1):204-220 |
1 | J:191793 Schnatwinkel C, Niswander L, Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice. PLoS One. 2012;7(9):e44871 |
1 | J:243381 Serafimidis I, Rodriguez-Aznar E, Lesche M, Yoshioka K, Takuwa Y, Dahl A, Pan D, Gavalas A, Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. PLoS Biol. 2017 Mar;15(3):e2000949 |
1 | J:338071 Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn LJ, Rosenthal B, Gurtler M, Estanboulieh RR, Shvartsman D, Gifford DK, Trapnell C, Melton D, A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets. Cell. 2019 Feb 7;176(4):790-804.e13 |
1* | J:31208 Shimoyama Y, Yoshida T, Terada M, Shimosato Y, Abe O, Hirohashi S, Molecular cloning of a human Ca2+-dependent cell-cell adhesion molecule homologous to mouse placental cadherin: its low expression in human placental tissues. J Cell Biol. 1989 Oct;109(4 Pt 1):1787-94 |
1* | J:335071 Siddam AD, Duot M, Coomson SY, Anand D, Aryal S, Weatherbee BAT, Audic Y, Paillard L, Lachke SA, High-Throughput Transcriptomics of Celf1 Conditional Knockout Lens Identifies Downstream Networks Linked to Cataract Pathology. Cells. 2023 Apr 1;12(7) |
1 | J:122566 Simirskii VN, Wang Y, Duncan MK, Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype. Dev Biol. 2007 Jun 15;306(2):658-68 |
2* | J:96963 Stemmler MP, Hecht A, Kemler R, E-cadherin intron 2 contains cis-regulatory elements essential for gene expression. Development. 2005 Mar;132(5):965-76 |
1 | J:361958 Straube P, Beckers A, Jany UWH, Bergmann F, Ludtke TH, Rudat C, Trowe MO, Peters I, Klopf MG, Mamo TM, Kispert A, Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter. Development. 2025 Feb 1;152(3) |
1 | J:154910 Sugiyama Y, Akimoto K, Robinson ML, Ohno S, Quinlan RA, A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol. 2009 Dec 15;336(2):246-56 |
1 | J:309439 Tang Y, Yang G, Zhang J, Li X, Zhang C, Wang Y, Xu J, Chen Y, Teng Y, Yang X, E-cadherin is Required for the Homeostasis of Lgr5(+) Gastric Antral Stem Cells. Int J Biol Sci. 2019;15(1):34-43 |
1 | J:159209 Tornqvist G, Sandberg A, Hagglund AC, Carlsson L, Cyclic expression of lhx2 regulates hair formation. PLoS Genet. 2010;6(4):e1000904 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
2 | J:178162 Trowe MO, Maier H, Petry M, Schweizer M, Schuster-Gossler K, Kispert A, Impaired stria vascularis integrity upon loss of E-cadherin in basal cells. Dev Biol. 2011 Nov 1;359(1):95-107 |
1 | J:266598 Ustiyan V, Bolte C, Zhang Y, Han L, Xu Y, Yutzey KE, Zorn AM, Kalin TV, Shannon JM, Kalinichenko VV, FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme. Dev Biol. 2018 Nov 1;443(1):50-63 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:302296 Vong KI, Ma TC, Li B, Leung TCN, Nong W, Ngai SM, Hui JHL, Jiang L, Kwan KM, SOX9-COL9A3-dependent regulation of choroid plexus epithelial polarity governs blood-cerebrospinal fluid barrier integrity. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2009568118 |
1 | J:338452 Wang D, Li H, Chandel NS, Dou Y, Yi R, MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters. Nat Commun. 2023 Jul 21;14(1):4404 |
2 | J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26 |
1 | J:340973 Wojahn I, Ludtke TH, Christoffels VM, Trowe MO, Kispert A, TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung. Respir Res. 2019 Dec 23;20(1):292 |
1 | J:301042 Wright D, Kiso M, Saga Y, Genetic and structural analysis of the in vivo functional redundancy between murine NANOS2 and NANOS3. Development. 2021 Jan 11;148(1):dev191916 |
1 | J:362739 Wu Y, Qin K, Xu Y, Rajhans S, Vo T, Lopez KM, Liu J, Nipper MH, Deng J, Yin X, Ramjit LR, Ye Z, Luan Y, Arda HE, Wang P, Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation. Elife. 2024 Jul 25;13 |
1 | J:313628 Xi L, Carroll T, Matos I, Luo JD, Polak L, Pasolli HA, Jaffrey SR, Fuchs E, m6A RNA methylation impacts fate choices during skin morphogenesis. Elife. 2020 Aug 26;9:e56980 |
1 | J:342871 Xiang J, Pompetti AJ, Faranda AP, Wang Y, Novo SG, Li DW, Duncan MK, ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment. Cells. 2023 Nov 16;12(22) |
2 | J:317033 Xie C, Abrams SR, Herranz-Perez V, Garcia-Verdugo JM, Reiter JF, Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity. Dev Cell. 2021 Dec 20;56(24):3334-3348.e6 |
1* | J:146829 Yamada W, Nagao K, Horikoshi K, Fujikura A, Ikeda E, Inagaki Y, Kakitani M, Tomizuka K, Miyazaki H, Suda T, Takubo K, Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun. 2009 Apr 10;381(3):453-8 |
1 | J:141958 Yang SH, Andl T, Grachtchouk V, Wang A, Liu J, Syu LJ, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA, Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta-catenin signaling. Nat Genet. 2008 Sep 1;40(9):1130-5 |
1 | J:242896 Yao C, Carraro G, Konda B, Guan X, Mizuno T, Chiba N, Kostelny M, Kurkciyan A, David G, McQualter JL, Stripp BR, Sin3a regulates epithelial progenitor cell fate during lung development. Development. 2017 Jul 15;144(14):2618-2628 |
1 | J:280538 Yeganeh B, Lee J, Ermini L, Lok I, Ackerley C, Post M, Autophagy is required for lung development and morphogenesis. J Clin Invest. 2019 Jun 4;129(7):2904-2919 |
1 | J:271268 Yui S, Azzolin L, Maimets M, Pedersen MT, Fordham RP, Hansen SL, Larsen HL, Guiu J, Alves MRP, Rundsten CF, Johansen JV, Li Y, Madsen CD, Nakamura T, Watanabe M, Nielsen OH, Schweiger PJ, Piccolo S, Jensen KB, YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration. Cell Stem Cell. 2018 Jan 4;22(1):35-49.e7 |
1 | J:332095 Zhang K, Yao E, Chuang E, Chen B, Chuang EY, Chuang PT, mTORC1 signaling facilitates differential stem cell differentiation to shape the developing murine lung and is associated with mitochondrial capacity. Nat Commun. 2022 Nov 25;13(1):7252 |
1 | J:125580 Zhang L, Deng M, Kao CW, Kao WW, Xia Y, MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis. Mol Vis. 2003 Nov 3;9:584-93 |
1 | J:225082 Zhang LJ, Bhattacharya S, Leid M, Ganguli-Indra G, Indra AK, Ctip2 is a dynamic regulator of epidermal proliferation and differentiation by integrating EGFR and Notch signaling. J Cell Sci. 2012 Dec 1;125(Pt 23):5733-44 |
1 | J:146244 Zuklys S, Gill J, Keller MP, Hauri-Hohl M, Zhanybekova S, Balciunaite G, Na KJ, Jeker LT, Hafen K, Tsukamoto N, Amagai T, Taketo MM, Krenger W, Hollander GA, Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. J Immunol. 2009 Mar 1;182(5):2997-3007 |
Cdh2 cadherin 2 (Synonyms: Ncad, N-CAD, N-cadherin) | |
Results | Reference |
1 | J:278104 Acebedo AR, Suzuki K, Hino S, Alcantara MC, Sato Y, Haga H, Matsumoto KI, Nakao M, Shimamura K, Takeo T, Nakagata N, Miyagawa S, Nishinakamura R, Adelstein RS, Yamada G, Mesenchymal actomyosin contractility is required for androgen-driven urethral masculinization in mice. Commun Biol. 2019;2:95 |
1 | J:321578 Ang PS, Matrongolo MJ, Tischfield MA, The growth and expansion of meningeal lymphatic networks are affected in craniosynostosis. Development. 2022 Jan 1;149(1):dev200065 |
1 | J:313612 Arimura N, Okada M, Taya S, Dewa KI, Tsuzuki A, Uetake H, Miyashita S, Hashizume K, Shimaoka K, Egusa S, Nishioka T, Yanagawa Y, Yamakawa K, Inoue YU, Inoue T, Kaibuchi K, Hoshino M, DSCAM regulates delamination of neurons in the developing midbrain. Sci Adv. 2020 Sep;6(36) |
1 | J:228518 Arya P, Rainey MA, Bhattacharyya S, Mohapatra BC, George M, Kuracha MR, Storck MD, Band V, Govindarajan V, Band H, The endocytic recycling regulatory protein EHD1 Is required for ocular lens development. Dev Biol. 2015 Dec 1;408(1):41-55 |
1 | J:194489 Chen SR, Chen M, Wang XN, Zhang J, Wen Q, Ji SY, Zheng QS, Gao F, Liu YX, The wilms tumor gene, wt1, maintains testicular cord integrity by regulating the expression of col4a1 and col4a2. Biol Reprod. 2013;88(3):56 |
1* | J:225905 Dash S, Dang CA, Beebe DC, Lachke SA, Deficiency of the RNA binding protein caprin2 causes lens defects and features of peters anomaly. Dev Dyn. 2015 Oct;244(10):1313-27 |
1 | J:198427 Dudok JJ, Sanz AS, Lundvig DM, Wijnholds J, MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. J Neurosci. 2013 May 8;33(19):8518-27 |
1 | J:172287 Esteve P, Sandonis A, Cardozo M, Malapeira J, Ibanez C, Crespo I, Marcos S, Gonzalez-Garcia S, Toribio ML, Arribas J, Shimono A, Guerrero I, Bovolenta P, SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis. Nat Neurosci. 2011 May;14(5):562-9 |
1 | J:301041 Guo D, Ru J, Mao F, Ouyang H, Ju R, Wu K, Liu Y, Liu C, Ontogenesis of the tear drainage system requires Prickle1-driven polarized basement membrane deposition. Development. 2020 Nov 30;147(22):dev191726 |
1 | J:238096 Houlihan SL, Lanctot AA, Guo Y, Feng Y, Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis. Elife. 2016 Sep 24;5:e17823 |
1* | J:283394 Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S, Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162 |
1 | J:197573 Itoh Y, Moriyama Y, Hasegawa T, Endo TA, Toyoda T, Gotoh Y, Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition-like mechanism. Nat Neurosci. 2013 Apr;16(4):416-25 |
1* | J:220858 Kim JY, Song JY, Karnam S, Park JY, Lee JJ, Kim S, Cho SH, Common and distinctive localization patterns of Crumbs polarity complex proteins in the mammalian eye. Gene Expr Patterns. 2015 Jan;17(1):31-7 |
1 | J:299736 Laszlo ZI, Lele Z, Zoldi M, Miczan V, Mogor F, Simon GM, Mackie K, Kacskovics I, Cravatt BF, Katona I, ABHD4-dependent developmental anoikis safeguards the embryonic brain. Nat Commun. 2020 Aug 31;11(1):4363 |
1 | J:292113 Lin YN, Lee YS, Li SK, Tang TK, Loss of CPAP in developing mouse brain and its functional implication for human primary microcephaly. J Cell Sci. 2020 Jun 24;133(12):jcs243592 |
2 | J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134 |
1 | J:97478 Lu S, Borst DE, Horowits R, N-RAP expression during mouse heart development. Dev Dyn. 2005 May;233(1):201-12 |
2 | J:207861 Manthey AL, Lachke SA, FitzGerald PG, Mason RW, Scheiblin DA, McDonald JH, Duncan MK, Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development. Mech Dev. 2014 Feb;131:86-110 |
1 | J:220152 Marcos S, Nieto-Lopez F, Sandonis A, Cardozo MJ, Di Marco F, Esteve P, Bovolenta P, Secreted frizzled related proteins modulate pathfinding and fasciculation of mouse retina ganglion cell axons by direct and indirect mechanisms. J Neurosci. 2015 Mar 18;35(11):4729-40 |
1 | J:235675 Martinez-Garay I, Gil-Sanz C, Franco SJ, Espinosa A, Molnar Z, Mueller U, Cadherin 2/4 signaling via PTP1B and catenins is crucial for nucleokinesis during radial neuronal migration in the neocortex. Development. 2016 Jun 15;143(12):2121-34 |
1 | J:331057 Parichha A, Datta D, Suresh V, Chatterjee M, Holtzman MJ, Tole S, Dentate gyrus morphogenesis is regulated by beta-catenin function in hem-derived fimbrial glia. Development. 2022 Nov 1;149(21):dev200953 |
1 | J:137807 Phillips HM, Rhee HJ, Murdoch JN, Hildreth V, Peat JD, Anderson RH, Copp AJ, Chaudhry B, Henderson DJ, Disruption of planar cell polarity signaling results in congenital heart defects and cardiomyopathy attributable to early cardiomyocyte disorganization. Circ Res. 2007 Jul 20;101(2):137-45 |
2 | J:124218 Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan YN, Rakic P, Sestan N, Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci. 2007 Jul;10(7):819-27 |
2 | J:213479 Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, Yoshida N, PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Cereb Cortex. 2013 Aug;23(8):1824-35 |
1 | J:110263 Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM, Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat Neurosci. 2006 Jun;9(6):787-97 |
1 | J:163275 Snyder EM, Small CL, Bomgardner D, Xu B, Evanoff R, Griswold MD, Hinton BT, Gene expression in the efferent ducts, epididymis, and vas deferens during embryonic development of the mouse. Dev Dyn. 2010 Sep;239(9):2479-91 |
1 | J:206876 Song JY, Park R, Kim JY, Hughes L, Lu L, Kim S, Johnson RL, Cho SH, Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev Biol. 2014 Feb 15;386(2):281-90 |
1 | J:154910 Sugiyama Y, Akimoto K, Robinson ML, Ohno S, Quinlan RA, A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol. 2009 Dec 15;336(2):246-56 |
1 | J:326480 Terry BK, Park R, Cho SH, Crino PB, Kim S, Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex. Hum Mol Genet. 2022 Jun 22;31(12):1979-1996 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1* | J:336871 Toonen JA, Ronchetti A, Sidjanin DJ, A Disintegrin and Metalloproteinase10 (ADAM10) Regulates NOTCH Signaling during Early Retinal Development. PLoS One. 2016;11(5):e0156184 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:242341 Zhang J, Upadhya D, Lu L, Reneker LW, Fibroblast growth factor receptor 2 (FGFR2) is required for corneal epithelial cell proliferation and differentiation during embryonic development. PLoS One. 2015;10(1):e0117089 |
1 | J:146244 Zuklys S, Gill J, Keller MP, Hauri-Hohl M, Zhanybekova S, Balciunaite G, Na KJ, Jeker LT, Hafen K, Tsukamoto N, Amagai T, Taketo MM, Krenger W, Hollander GA, Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. J Immunol. 2009 Mar 1;182(5):2997-3007 |
Cdh3 cadherin 3 (Synonyms: Cadp, Pcad, P-cadherin) | |
Results | Reference |
1 | J:188155 Bharti K, Gasper M, Ou J, Brucato M, Clore-Gronenborn K, Pickel J, Arnheiter H, A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development. PLoS Genet. 2012 Jul;8(7):e1002757 |
1 | J:145627 Devenport D, Fuchs E, Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol. 2008 Nov;10(11):1257-68 |
1* | J:239434 Fleger-Weckmann A, Ustun Y, Kloepper J, Paus R, Bloch W, Chen ZL, Wegner J, Sorokin L, Langbein L, Eckes B, Zigrino P, Krieg T, Nischt R, Deletion of the epidermis derived laminin gamma1 chain leads to defects in the regulation of late hair morphogenesis. Matrix Biol. 2016 Dec;56:42-56 |
1 | J:202029 Folgueras AR, Guo X, Pasolli HA, Stokes N, Polak L, Zheng D, Fuchs E, Architectural niche organization by LHX2 is linked to hair follicle stem cell function. Cell Stem Cell. 2013 Sep 5;13(3):314-27 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:31205 Hirai Y, Nose A, Kobayashi S, Takeichi M, Expression and role of E- and P-cadherin adhesion molecules in embryonic histogenesis. II. Skin morphogenesis. Development. 1989 Feb;105(2):271-7 |
1 | J:193958 Huh SH, Narhi K, Lindfors PH, Haara O, Yang L, Ornitz DM, Mikkola ML, Fgf20 governs formation of primary and secondary dermal condensations in developing hair follicles. Genes Dev. 2013 Feb 15;27(4):450-8 |
1* | J:82378 Jamora C, DasGupta R, Kocieniewski P, Fuchs E, Links between signal transduction, transcription and adhesion in epithelial bud development. Nature. 2003 Mar 20;422(6929):317-22 |
1 | J:189074 Li ZJ, Nieuwenhuis E, Nien W, Zhang X, Zhang J, Puviindran V, Wainwright BJ, Kim PC, Hui CC, Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis. Development. 2012 Nov;139(22):4152-61 |
1 | J:352165 Lin Y, Tang W, Huang P, Wang Z, Duan L, Jia C, Sun R, Liu L, Shen J, Denticleless E3 ubiquitin protein ligase (DTL) maintains the proliferation and differentiation of epidermis and hair follicles during skin development. Dev Dyn. 2024 Jul;253(7):635-647 |
1 | J:182928 Nagarajan P, Chin SS, Wang D, Liu S, Sinha S, Garrett-Sinha LA, Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators. J Cell Sci. 2010 Oct 15;123(Pt 20):3566-75 |
1 | J:326948 Ng KJ, Lim J, Tan YN, Quek D, Lim Z, Pantelireis N, Clavel C, Sox2 in the dermal papilla regulates hair follicle pigmentation. Cell Rep. 2022 Jul 19;40(3):111100 |
1 | J:207286 Nowak JA, Polak L, Pasolli HA, Fuchs E, Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell. 2008 Jul 3;3(1):33-43 |
1 | J:48599 Obara N, Suzuki Y, Nagai Y, Takeda M, Expression of E- and P-cadherin during tooth morphogenesis and cytodifferentiation of ameloblasts. Anat Embryol (Berl). 1998 Jun;197(6):469-75 |
1 | J:149989 Richardson GD, Bazzi H, Fantauzzo KA, Waters JM, Crawford H, Hynd P, Christiano AM, Jahoda CA, KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin. Development. 2009 Jul;136(13):2153-64 |
1 | J:266746 Rudkouskaya A, Welch I, Dagnino L, ILK modulates epithelial polarity and matrix formation in hair follicles. Mol Biol Cell. 2014 Mar;25(5):620-32 |
1* | J:31208 Shimoyama Y, Yoshida T, Terada M, Shimosato Y, Abe O, Hirohashi S, Molecular cloning of a human Ca2+-dependent cell-cell adhesion molecule homologous to mouse placental cadherin: its low expression in human placental tissues. J Cell Biol. 1989 Oct;109(4 Pt 1):1787-94 |
1 | J:313628 Xi L, Carroll T, Matos I, Luo JD, Polak L, Pasolli HA, Jaffrey SR, Fuchs E, m6A RNA methylation impacts fate choices during skin morphogenesis. Elife. 2020 Aug 26;9:e56980 |
1 | J:141958 Yang SH, Andl T, Grachtchouk V, Wang A, Liu J, Syu LJ, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA, Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta-catenin signaling. Nat Genet. 2008 Sep 1;40(9):1130-5 |
Cdh4 cadherin 4 (Synonyms: Rcad, R-Cadh, R-cadherin) | |
Results | Reference |
1 | J:137605 Manuel M, Pratt T, Liu M, Jeffery G, Price DJ, Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance. BMC Dev Biol. 2008;8:59 |
1 | J:235675 Martinez-Garay I, Gil-Sanz C, Franco SJ, Espinosa A, Molnar Z, Mueller U, Cadherin 2/4 signaling via PTP1B and catenins is crucial for nucleokinesis during radial neuronal migration in the neocortex. Development. 2016 Jun 15;143(12):2121-34 |
1* | J:29896 Sjodin A, Dahl U, Semb H, Mouse R-cadherin: expression during the organogenesis of pancreas and gastrointestinal tract. Exp Cell Res. 1995 Dec;221(2):413-25 |
Cdh5 cadherin 5 (Synonyms: 7B4/cadherin-5, CD144, VEC, VEcad, VE-Cad, VE-cadherin, VECD) | |
Results | Reference |
2 | J:253618 Bonney S, Siegenthaler JA, Differential Effects of Retinoic Acid Concentrations in Regulating Blood-Brain Barrier Properties. eNeuro. 2017 May-Jun;4(3):ENEURO.0378-16.2017 |
1* | J:30623 Breier G, Breviario F, Caveda L, Berthier R, Schnurch H, Gotsch U, Vestweber D, Risau W, Dejana E, Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system. (Errata: vol. 88(3):1129-33). Blood. 1996 Jan 15;87(2):630-41 |
1* | J:243789 Chang AH, Raftrey BC, D'Amato G, Surya VN, Poduri A, Chen HI, Goldstone AB, Woo J, Fuller GG, Dunn AR, Red-Horse K, DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12-CXCR4 signaling axis. Genes Dev. 2017 Aug 04;31(13):1308-1324 |
2 | J:217615 Chen HI, Poduri A, Numi H, Kivela R, Saharinen P, McKay AS, Raftrey B, Churko J, Tian X, Zhou B, Wu JC, Alitalo K, Red-Horse K, VEGF-C and aortic cardiomyocytes guide coronary artery stem development. J Clin Invest. 2014 Nov;124(11):4899-914 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1 | J:204443 Egan CM, Nyman U, Skotte J, Streubel G, Turner S, O'Connell DJ, Rraklli V, Dolan MJ, Chadderton N, Hansen K, Farrar GJ, Helin K, Holmberg J, Bracken AP, CHD5 is required for neurogenesis and has a dual role in facilitating gene expression and polycomb gene repression. Dev Cell. 2013 Aug 12;26(3):223-36 |
1 | J:362521 Guo XL, Wang YD, Liu YJ, Chu L, Zhu H, Hu Y, Wu RY, Xie HY, Yu J, Li SP, Xiong CY, Li RY, Ke F, Chen L, Chen GQ, Chen L, Bai F, Enver T, Li GH, Li HF, Hong DL, Fetal hepatocytes protect the HSPC genome via fetuin-A. Nature. 2025 Jan;637(8045):402-411 |
1 | J:239651 Hurtado R, Zewdu R, Mtui J, Liang C, Aho R, Kurylo C, Selleri L, Herzlinger D, Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning. Development. 2015 Aug 01;142(15):2653-64 |
1 | J:199291 Jiang M, Ku WY, Fu J, Offermanns S, Hsu W, Que J, Gpr177 regulates pulmonary vasculature development. Development. 2013 Sep;140(17):3589-94 |
1 | J:334530 Li SY, Bhandary B, Gu X, DeFalco T, Perivascular cells support folliculogenesis in the developing ovary. Proc Natl Acad Sci U S A. 2022 Oct 11;119(41):e2213026119 |
1 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
1 | J:339241 Liu, K., Intercellular genetic tracing of cardiac endothelium in the developing heart. Dev Cell. 2023 Aug 21;58(16):1502-1512 |
1 | J:317975 Lu P, Wang Y, Liu Y, Wang Y, Wu B, Zheng D, Harvey RP, Zhou B, Perinatal angiogenesis from pre-existing coronary vessels via DLL4-NOTCH1 signalling. Nat Cell Biol. 2021 Sep;23(9):967-977 |
1 | J:284120 Mahamud MR, Geng X, Ho YC, Cha B, Kim Y, Ma J, Chen L, Myers G, Camper S, Mustacich D, Witte M, Choi D, Hong YK, Chen H, Varshney G, Engel JD, Wang S, Kim TH, Lim KC, Srinivasan RS, GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126. Development. 2019 Nov 5;146(21):dev184218 |
1 | J:352884 Miura A, Sarmah H, Tanaka J, Hwang Y, Sawada A, Shimamura Y, Otoshi T, Kondo Y, Fang Y, Shimizu D, Ninish Z, Suer JL, Dubois NC, Davis J, Toyooka S, Wu J, Que J, Hawkins FJ, Lin CS, Mori M, Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes the generation of the whole lung. Elife. 2023 Oct 20;12 |
1 | J:207212 Oh WJ, Gu C, Establishment of neurovascular congruency in the mouse whisker system by an independent patterning mechanism. Neuron. 2013 Oct 16;80(2):458-69 |
1 | J:317613 Patnaik SR, Kretschmer V, Brucker L, Schneider S, Volz AK, Oancea-Castillo LDR, May-Simera HL, Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation. Cell Mol Life Sci. 2019 Feb;76(4):757-775 |
2 | J:281274 Qu X, Violette K, Sewell-Loftin MK, Soslow J, Saint-Jean L, Hinton RB, Merryman WD, Baldwin HS, Loss of flow responsive Tie1 results in ImpairedAortic valve remodeling. Dev Biol. 2019 Nov 1;455(1):73-84 |
1 | J:181330 Sabine A, Agalarov Y, Maby-El Hajjami H, Jaquet M, Hagerling R, Pollmann C, Bebber D, Pfenniger A, Miura N, Dormond O, Calmes JM, Adams RH, Makinen T, Kiefer F, Kwak BR, Petrova TV, Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation. Dev Cell. 2012 Feb 14;22(2):430-45 |
1 | J:245878 Sharma B, Ho L, Ford GH, Chen HI, Goldstone AB, Woo YJ, Quertermous T, Reversade B, Red-Horse K, Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts. Dev Cell. 2017 Sep 25;42(6):655-666.e3 |
1* | J:341715 Sui Y, Kou S, Ge K, Cao J, Liu C, Zhang H, Expression analysis of plvap in mouse heart development, homeostasis and injury. Gene Expr Patterns. 2023 Sep 28;50:119343 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:361664 Vitali HE, Kuschel B, Sherpa C, Jones BW, Jacob N, Madiha SA, Elliott S, Dziennik E, Kreun L, Conatser C, Bhetwal BP, Sharma B, Hypoxia regulate developmental coronary angiogenesis potentially through VEGF-R2- and SOX17-mediated signaling. Dev Dyn. 2025 Feb;254(2):174-188 |
1 | J:229606 Volz KS, Jacobs AH, Chen HI, Poduri A, McKay AS, Riordan DP, Kofler N, Kitajewski J, Weissman I, Red-Horse K, Pericytes are progenitors for coronary artery smooth muscle. Elife. 2015;4:e10036 |
1 | J:137812 Vondenhoff MF, Desanti GE, Cupedo T, Bertrand JY, Cumano A, Kraal G, Mebius RE, Golub R, Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner. J Leukoc Biol. 2008 Jul;84(1):152-61 |
1 | J:150308 Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009 May 1;182(9):5439-45 |
1 | J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:278463 Yang Y, Cha B, Motawe ZY, Srinivasan RS, Scallan JP, VE-Cadherin Is Required for Lymphatic Valve Formation and Maintenance. Cell Rep. 2019;28(9):2397-2412 |
1 | J:184806 Yao LC, Baluk P, Srinivasan RS, Oliver G, McDonald DM, Plasticity of button-like junctions in the endothelium of airway lymphatics in development and inflammation. Am J Pathol. 2012 Jun;180(6):2561-75 |
1 | J:306543 Yu Z, Zeng J, Wang J, Cui Y, Song X, Zhang Y, Cheng X, Hou N, Teng Y, Lan Y, Chen Y, Yang X, Hepatocyte growth factor-regulated tyrosine kinase substrate is essential for endothelial cell polarity and cerebrovascular stability. Cardiovasc Res. 2021 Jan 21;117(2):533-546 |
Cdh6 cadherin 6 (Synonyms: cad6, K-cadherin) | |
Results | Reference |
1* | J:208419 Basta JM, Robbins L, Kiefer SM, Dorsett D, Rauchman M, Sall1 balances self-renewal and differentiation of renal progenitor cells. Development. 2014 Mar;141(5):1047-58 |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1* | J:79830 Garel S, Yun K, Grosschedl R, Rubenstein JL, The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development. 2002 Dec;129(24):5621-34 |
1 | J:46909 Inoue T, Tanaka T, Suzuki SC, Takeichi M, Cadherin-6 in the developing mouse brain: expression along restricted connection systems and synaptic localization suggest a potential role in neuronal circuitry. Dev Dyn. 1998 Apr;211(4):338-51 |
1* | J:186285 Lefkovics K, Mayer M, Bercsenyi K, Szabo G, Lele Z, Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy. J Comp Neurol. 2012 May 1;520(7):1387-1405 |
1 | J:78452 Marthiens V, Padilla F, Lambert M, Mege RM, Complementary Expression and Regulation of Cadherins 6 and 11 during Specific Steps of Motoneuron Differentiation. Mol Cell Neurosci. 2002 Jul;20(3):458-75 |
1 | J:235675 Martinez-Garay I, Gil-Sanz C, Franco SJ, Espinosa A, Molnar Z, Mueller U, Cadherin 2/4 signaling via PTP1B and catenins is crucial for nucleokinesis during radial neuronal migration in the neocortex. Development. 2016 Jun 15;143(12):2121-34 |
2* | J:48958 Padilla F, Broders F, Nicolet M, Mege RM, Cadherins M, 11, and 6 expression patterns suggest complementary roles in mouse neuromuscular axis development. Mol Cell Neurosci. 1998 Jul;11(4):217-33 |
Cdh7 cadherin 7, type 2 (Synonyms: 9330156F07Rik, CDH7L1) | |
Results | Reference |
1* | J:186285 Lefkovics K, Mayer M, Bercsenyi K, Szabo G, Lele Z, Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy. J Comp Neurol. 2012 May 1;520(7):1387-1405 |
Cdh8 cadherin 8 (Synonyms: cad8) | |
Results | Reference |
1 | J:127387 Armentano M, Chou SJ, Tomassy GS, Leingartner A, O'Leary DD, Studer M, COUP-TFI regulates the balance of cortical patterning between frontal/motor and sensory areas. Nat Neurosci. 2007 Oct;10(10):1277-86 |
1* | J:184357 Dye CA, El Shawa H, Huffman KJ, A lifespan analysis of intraneocortical connections and gene expression in the mouse I. Cereb Cortex. 2011 Jun;21(6):1311-30 |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:44591 Garel S, Marin F, Grosschedl R, Charnay P, Ebf1 controls early cell differentiation in the embryonic striatum. Development. 1999 Dec;126(23):5285-94 |
1* | J:79830 Garel S, Yun K, Grosschedl R, Rubenstein JL, The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development. 2002 Dec;129(24):5621-34 |
2 | J:208050 Huang TN, Chuang HC, Chou WH, Chen CY, Wang HF, Chou SJ, Hsueh YP, Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality. Nat Neurosci. 2014 Feb;17(2):240-7 |
1* | J:186285 Lefkovics K, Mayer M, Bercsenyi K, Szabo G, Lele Z, Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy. J Comp Neurol. 2012 May 1;520(7):1387-1405 |
1* | J:114661 Lyu YL, Lin CP, Azarova AM, Cai L, Wang JC, Liu LF, Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Mol Cell Biol. 2006 Nov;26(21):7929-41 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
Cdh9 cadherin 9 (Synonyms: T1-cadherin) | |
Results | Reference |
1* | J:186285 Lefkovics K, Mayer M, Bercsenyi K, Szabo G, Lele Z, Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy. J Comp Neurol. 2012 May 1;520(7):1387-1405 |
Cdh10 cadherin 10 (Synonyms: A830016G23Rik, C030003B10Rik, C030011H18Rik, T2-cadherin) | |
Results | Reference |
1* | J:186285 Lefkovics K, Mayer M, Bercsenyi K, Szabo G, Lele Z, Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy. J Comp Neurol. 2012 May 1;520(7):1387-1405 |
Cdh11 cadherin 11 (Synonyms: Cad11, OB-cadherin, osteoblast-cadherin) | |
Results | Reference |
1* | J:25269 Hoffmann I, Balling R, Cloning and expression analysis of a novel mesodermally expressed cadherin. Dev Biol. 1995 May;169(1):337-46 |
1* | J:34538 Kimura Y, Matsunami H, Takeichi M, Expression of cadherin-11 delineates boundaries, neuromeres, and nuclei in the developing mouse brain. Dev Dyn. 1996 Aug;206(4):455-62 |
2* | J:316202 Kiyama Y, Kikkawa YS, Kinoshita M, Matsumoto Y, Kondo K, Fujimoto C, Iwasaki S, Yamasoba T, Manabe T, The adhesion molecule cadherin 11 is essential for acquisition of normal hearing ability through middle ear development in the mouse. Lab Invest. 2018 Nov;98(11):1364-1374 |
1* | J:186285 Lefkovics K, Mayer M, Bercsenyi K, Szabo G, Lele Z, Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy. J Comp Neurol. 2012 May 1;520(7):1387-1405 |
1 | J:235675 Martinez-Garay I, Gil-Sanz C, Franco SJ, Espinosa A, Molnar Z, Mueller U, Cadherin 2/4 signaling via PTP1B and catenins is crucial for nucleokinesis during radial neuronal migration in the neocortex. Development. 2016 Jun 15;143(12):2121-34 |
2* | J:48958 Padilla F, Broders F, Nicolet M, Mege RM, Cadherins M, 11, and 6 expression patterns suggest complementary roles in mouse neuromuscular axis development. Mol Cell Neurosci. 1998 Jul;11(4):217-33 |
1 | J:182304 Ross SE, McCord AE, Jung C, Atan D, Mok SI, Hemberg M, Kim TK, Salogiannis J, Hu L, Cohen S, Lin Y, Harrar D, McInnes RR, Greenberg ME, Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly. Neuron. 2012 Jan 26;73(2):292-303 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Cdh12 cadherin 12 (Synonyms: Br-cadherin) | |
Results | Reference |
1* | J:186285 Lefkovics K, Mayer M, Bercsenyi K, Szabo G, Lele Z, Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy. J Comp Neurol. 2012 May 1;520(7):1387-1405 |
1* | J:164032 Mayer M, Bercsenyi K, Geczi K, Szabo G, Lele Z, Expression of two type II cadherins, Cdh12 and Cdh22 in the developing and adult mouse brain. Gene Expr Patterns. 2010 October - December;10(7-8):351-360 |
Cdh13 cadherin 13 (Synonyms: 4932416G01Rik, Tcad, T-cadherin) | |
Results | Reference |
1 | J:235675 Martinez-Garay I, Gil-Sanz C, Franco SJ, Espinosa A, Molnar Z, Mueller U, Cadherin 2/4 signaling via PTP1B and catenins is crucial for nucleokinesis during radial neuronal migration in the neocortex. Development. 2016 Jun 15;143(12):2121-34 |
Cdh15 cadherin 15 (Synonyms: Cdh14, Mcad, M cadherin) | |
Results | Reference |
1 | J:66277 Beauchamp JR, Heslop L, Yu DS, Tajbakhsh S, Kelly RG, Wernig A, Buckingham ME, Partridge TA, Zammit PS, Expression of CD34 and myf5 defines the majority of quiescent adult skeletal muscle satellite cells. J Cell Biol. 2000 Dec 11;151(6):1221-34 |
3 | J:36170 Cifuentes-Diaz C, Goudou D, Padilla F, Facchinetti P, Nicolet M, Mege RM, Rieger F, M-cadherin distribution in the mouse adult neuromuscular system suggests a role in muscle innervation. Eur J Neurosci. 1996 Aug;8(8):1666-76 |
1* | J:23910 Cifuentes-Diaz C, Nicolet M, Alameddine H, Goudou D, Dehaupas M, Rieger F, Mege RM, M-cadherin localization in developing adult and regenerating mouse skeletal muscle: possible involvement in secondary myogenesis. Mech Dev. 1995 Mar;50(1):85-97 |
1 | J:198427 Dudok JJ, Sanz AS, Lundvig DM, Wijnholds J, MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. J Neurosci. 2013 May 8;33(19):8518-27 |
2* | J:48958 Padilla F, Broders F, Nicolet M, Mege RM, Cadherins M, 11, and 6 expression patterns suggest complementary roles in mouse neuromuscular axis development. Mol Cell Neurosci. 1998 Jul;11(4):217-33 |
Cdh17 cadherin 17 (Synonyms: BILL-cadherin, HPT-1, LI-cadherin) | |
Results | Reference |
1* | J:69761 Angres B, Kim L, Jung R, Gessner R, Tauber R, LI-cadherin gene expression during mouse intestinal development. Dev Dyn. 2001 Jun;221(2):182-93 |
Cdh18 cadherin 18 (Synonyms: B230220E17Rik) | |
Results | Reference |
1* | J:186285 Lefkovics K, Mayer M, Bercsenyi K, Szabo G, Lele Z, Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy. J Comp Neurol. 2012 May 1;520(7):1387-1405 |
Cdh19 cadherin 19, type 2 | |
Results | Reference |
1* | J:186285 Lefkovics K, Mayer M, Bercsenyi K, Szabo G, Lele Z, Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy. J Comp Neurol. 2012 May 1;520(7):1387-1405 |
Cdh20 cadherin 20 (Synonyms: Cdh7) | |
Results | Reference |
1* | J:186285 Lefkovics K, Mayer M, Bercsenyi K, Szabo G, Lele Z, Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy. J Comp Neurol. 2012 May 1;520(7):1387-1405 |
Cdh22 cadherin 22 (Synonyms: PB-cadherin) | |
Results | Reference |
1* | J:56108 Kitajima K, Koshimizu U, Nakamura T, Expression of a novel type of classic cadherin, PB-cadherin in developing brain and limb buds. Dev Dyn. 1999 Jul;215(3):206-14 |
1* | J:186285 Lefkovics K, Mayer M, Bercsenyi K, Szabo G, Lele Z, Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy. J Comp Neurol. 2012 May 1;520(7):1387-1405 |
1* | J:164032 Mayer M, Bercsenyi K, Geczi K, Szabo G, Lele Z, Expression of two type II cadherins, Cdh12 and Cdh22 in the developing and adult mouse brain. Gene Expr Patterns. 2010 October - December;10(7-8):351-360 |
Cdh23 cadherin related 23 (otocadherin) (Synonyms: 4930542A03Rik, ahl, bob, mdfw, nmf112, nmf181, nmf252, sals, USH1D) | |
Results | Reference |
1 | J:80836 Boeda B, El-Amraoui A, Bahloul A, Goodyear R, Daviet L, Blanchard S, Perfettini I, Fath KR, Shorte S, Reiners J, Houdusse A, Legrain P, Wolfrum U, Richardson G, Petit C, Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle. EMBO J. 2002 Dec 16;21(24):6689-99 |
1 | J:98268 Lagziel A, Ahmed ZM, Schultz JM, Morell RJ, Belyantseva IA, Friedman TB, Spatiotemporal pattern and isoforms of cadherin 23 in wild type and waltzer mice during inner ear hair cell development. Dev Biol. 2005 Apr 15;280(2):295-306 |
1 | J:263485 Lagziel A, Overlack N, Bernstein SL, Morell RJ, Wolfrum U, Friedman TB, Expression of cadherin 23 isoforms is not conserved: implications for a mouse model of Usher syndrome type 1D. Mol Vis. 2009 Sep 12;15:1843-57 |
1 | J:135991 Lefevre G, Michel V, Weil D, Lepelletier L, Bizard E, Wolfrum U, Hardelin JP, Petit C, A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth. Development. 2008 Apr;135(8):1427-37 |
Cdh24 cadherin-like 24 (Synonyms: 1700040A22Rik, cadherin 14-like, ENSMUSG00000022188, EY-cadherin, MGC:67331) | |
Results | Reference |
1* | J:186285 Lefkovics K, Mayer M, Bercsenyi K, Szabo G, Lele Z, Comparative analysis of type II classic cadherin mRNA distribution patterns in the developing and adult mouse somatosensory cortex and hippocampus suggests significant functional redundancy. J Comp Neurol. 2012 May 1;520(7):1387-1405 |
Cdk1 cyclin dependent kinase 1
(Synonyms:
Cdc2, Cdc2a, p34 | |
Results | Reference |
1* | J:108720 Berthet C, Klarmann KD, Hilton MB, Suh HC, Keller JR, Kiyokawa H, Kaldis P, Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation. Dev Cell. 2006 May;10(5):563-73 |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:216295 Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC, FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. 2014 Nov 1;395(1):50-61 |
1 | J:190540 Ikenishi A, Okayama H, Iwamoto N, Yoshitome S, Tane S, Nakamura K, Obayashi T, Hayashi T, Takeuchi T, Cell cycle regulation in mouse heart during embryonic and postnatal stages. Dev Growth Differ. 2012 Oct;54(8):731-8 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
1 | J:329315 Sheldon C, Farley A, Ma Q, Pu WT, Lin Z, Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development. Cells. 2022 Sep 10;11(18) |
1* | J:26610 Zhao J, Nornes HO, Neuman T, Expression of Rb, E2F1, cdc2, and D, and B cyclins in developing spinal cord. Neurosci Lett. 1995 Apr 28;190(1):49-52 |
Cdk2 cyclin dependent kinase 2 (Synonyms: A630093N05Rik) | |
Results | Reference |
1* | J:108720 Berthet C, Klarmann KD, Hilton MB, Suh HC, Keller JR, Kiyokawa H, Kaldis P, Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation. Dev Cell. 2006 May;10(5):563-73 |
2* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1* | J:168656 Ikeda Y, Matsunaga Y, Takiguchi M, Ikeda MA, Expression of cyclin E in postmitotic neurons during development and in the adult mouse brain. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):64-71 |
1 | J:190540 Ikenishi A, Okayama H, Iwamoto N, Yoshitome S, Tane S, Nakamura K, Obayashi T, Hayashi T, Takeuchi T, Cell cycle regulation in mouse heart during embryonic and postnatal stages. Dev Growth Differ. 2012 Oct;54(8):731-8 |
1 | J:178882 Odajima J, Wills ZP, Ndassa YM, Terunuma M, Kretschmannova K, Deeb TZ, Geng Y, Gawrzak S, Quadros IM, Newman J, Das M, Jecrois ME, Yu Q, Li N, Bienvenu F, Moss SJ, Greenberg ME, Marto JA, Sicinski P, Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation. Dev Cell. 2011 Oct 18;21(4):655-68 |
1 | J:48539 Sunters A, McCluskey J, Grigoriadis AE, Control of cell cycle gene expression in bone development and during c-Fos-induced osteosarcoma formation. Dev Genet. 1998;22(4):386-97 |
Cdk2ap1 cyclin dependent kinase 2 associated protein 1 (Synonyms: Doc1, DORC1, p12, ST19) | |
Results | Reference |
1* | J:120114 Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY, A biphasic pattern of gene expression during mouse retina development. BMC Dev Biol. 2006;6:48 |
Cdk4 cyclin dependent kinase 4
(Synonyms:
Crk3, p34 | |
Results | Reference |
1* | J:108720 Berthet C, Klarmann KD, Hilton MB, Suh HC, Keller JR, Kiyokawa H, Kaldis P, Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation. Dev Cell. 2006 May;10(5):563-73 |
1 | J:216295 Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC, FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. 2014 Nov 1;395(1):50-61 |
1 | J:190540 Ikenishi A, Okayama H, Iwamoto N, Yoshitome S, Tane S, Nakamura K, Obayashi T, Hayashi T, Takeuchi T, Cell cycle regulation in mouse heart during embryonic and postnatal stages. Dev Growth Differ. 2012 Oct;54(8):731-8 |
1 | J:311844 Landin MA, Nygard S, Shabestari MG, Babaie E, Reseland JE, Osmundsen H, Mapping the global mRNA transcriptome during development of the murine first molar. Front Genet. 2015;6:47 |
1 | J:171273 Nakajima K, Inagawa M, Uchida C, Okada K, Tane S, Kojima M, Kubota M, Noda M, Ogawa S, Shirato H, Sato M, Suzuki-Migishima R, Hino T, Satoh Y, Kitagawa M, Takeuchi T, Coordinated regulation of differentiation and proliferation of embryonic cardiomyocytes by a jumonji (Jarid2)-cyclin D1 pathway. Development. 2011 May;138(9):1771-82 |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
1* | J:32244 Sun W, Lee DK, Lee CC, Kim K, Differential expression of D-type G1 cyclins during mouse development and liver regeneration in vivo. Mol Reprod Dev. 1996 Apr;43(4):414-20 |
1 | J:48539 Sunters A, McCluskey J, Grigoriadis AE, Control of cell cycle gene expression in bone development and during c-Fos-induced osteosarcoma formation. Dev Genet. 1998;22(4):386-97 |
1* | J:305372 Tian H, She Z, Gao X, Wang W, Tian H, MicroRNA-31 regulates dental epithelial cell proliferation by targeting Satb2. Biochem Biophys Res Commun. 2020 Nov 5;532(2):321-328 |
1* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
1 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
Cdk5 cyclin dependent kinase 5 (Synonyms: Crk6) | |
Results | Reference |
1 | J:59870 Han SH, Morgan JI, Comparison of munc-18 and cdk5 expression in the nervous system during mouse embryogenesis. Neuroscience. 1999;94(3):955-64 |
1* | J:168656 Ikeda Y, Matsunaga Y, Takiguchi M, Ikeda MA, Expression of cyclin E in postmitotic neurons during development and in the adult mouse brain. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):64-71 |
1 | J:20997 Ino H, Ishizuka T, Chiba T, Tatibana M, Expression of CDK5 (PSSALRE kinase), a neural cdc2-related protein kinase, in the mature and developing mouse central and peripheral nervous systems. Brain Res. 1994 Oct 24;661(1-2):196-206 |
3 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
1 | J:178882 Odajima J, Wills ZP, Ndassa YM, Terunuma M, Kretschmannova K, Deeb TZ, Geng Y, Gawrzak S, Quadros IM, Newman J, Das M, Jecrois ME, Yu Q, Li N, Bienvenu F, Moss SJ, Greenberg ME, Marto JA, Sicinski P, Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation. Dev Cell. 2011 Oct 18;21(4):655-68 |
1 | J:77999 Sugitani Y, Nakai S, Minowa O, Nishi M, Jishage K, Kawano H, Mori K, Ogawa M, Noda T, Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. Genes Dev. 2002 Jul 15;16(14):1760-5 |
2 | J:16556 Tsai LH, Takahashi T, Caviness VS Jr, Harlow E, Activity and expression pattern of cyclin-dependent kinase 5 in the embryonic mouse nervous system. Development. 1993 Dec;119(4):1029-40 |
1 | J:159853 Zhang J, Li H, Yabut O, Fitzpatrick H, D'Arcangelo G, Herrup K, Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex. J Neurosci. 2010 Apr 14;30(15):5219-28 |
1 | J:219874 Zhou J, Li H, Li X, Zhang G, Niu Y, Yuan Z, Herrup K, Zhang YW, Bu G, Xu H, Zhang J, The roles of Cdk5-mediated subcellular localization of FOXO1 in neuronal death. J Neurosci. 2015 Feb 11;35(6):2624-35 |
Cdk5r1 cyclin dependent kinase 5, regulatory subunit 1 (Synonyms: D11Bwg0379e, p25, p35) | |
Results | Reference |
2 | J:107294 Chang Y, Ostling P, Akerfelt M, Trouillet D, Rallu M, Gitton Y, El Fatimy R, Fardeau V, Le Crom S, Morange M, Sistonen L, Mezger V, Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expression. Genes Dev. 2006 Apr 1;20(7):836-47 |
1* | J:168656 Ikeda Y, Matsunaga Y, Takiguchi M, Ikeda MA, Expression of cyclin E in postmitotic neurons during development and in the adult mouse brain. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):64-71 |
1 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
1 | J:178882 Odajima J, Wills ZP, Ndassa YM, Terunuma M, Kretschmannova K, Deeb TZ, Geng Y, Gawrzak S, Quadros IM, Newman J, Das M, Jecrois ME, Yu Q, Li N, Bienvenu F, Moss SJ, Greenberg ME, Marto JA, Sicinski P, Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation. Dev Cell. 2011 Oct 18;21(4):655-68 |
1* | J:67864 Ohshima T, Ogawa M, Veeranna, Hirasawa M, Longenecker G, Ishiguro K, Pant HC, Brady RO, Kulkarni AB, Mikoshiba K, Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain. Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2764-9 |
2 | J:77999 Sugitani Y, Nakai S, Minowa O, Nishi M, Jishage K, Kawano H, Mori K, Ogawa M, Noda T, Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. Genes Dev. 2002 Jul 15;16(14):1760-5 |
1 | J:159853 Zhang J, Li H, Yabut O, Fitzpatrick H, D'Arcangelo G, Herrup K, Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex. J Neurosci. 2010 Apr 14;30(15):5219-28 |
Cdk5r2 cyclin dependent kinase 5, regulatory subunit 2 (Synonyms: B230310J22Rik, p39) | |
Results | Reference |
2 | J:107294 Chang Y, Ostling P, Akerfelt M, Trouillet D, Rallu M, Gitton Y, El Fatimy R, Fardeau V, Le Crom S, Morange M, Sistonen L, Mezger V, Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expression. Genes Dev. 2006 Apr 1;20(7):836-47 |
1* | J:67864 Ohshima T, Ogawa M, Veeranna, Hirasawa M, Longenecker G, Ishiguro K, Pant HC, Brady RO, Kulkarni AB, Mikoshiba K, Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain. Proc Natl Acad Sci U S A. 2001 Feb 27;98(5):2764-9 |
Cdk5rap3 CDK5 regulatory subunit associated protein 3 (Synonyms: 1810007E24Rik, C53, HSF-27, IC53, MGC:8303, MST016, OK/SW-cl.114) | |
Results | Reference |
2* | J:272566 Yang R, Wang H, Kang B, Chen B, Shi Y, Yang S, Sun L, Liu Y, Xiao W, Zhang T, Yang J, Zhang Y, Zhu M, Xu P, Chang Y, Jia Y, Huang Y, CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235 |
Cdk6 cyclin dependent kinase 6 (Synonyms: Crk2) | |
Results | Reference |
1* | J:108720 Berthet C, Klarmann KD, Hilton MB, Suh HC, Keller JR, Kiyokawa H, Kaldis P, Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation. Dev Cell. 2006 May;10(5):563-73 |
1* | J:199186 Juuri E, Saito K, Lefebvre S, Michon F, Establishment of crown-root domain borders in mouse incisor. Gene Expr Patterns. 2013 Oct;13(7):255-64 |
1* | J:305376 Li B, Wang Z, Yang F, Huang J, Hu X, Deng S, Tian M, Si X, miR449a5p suppresses CDK6 expression to inhibit cardiomyocyte proliferation. Mol Med Rep. 2021 Jan;23(1) |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
1 | J:48539 Sunters A, McCluskey J, Grigoriadis AE, Control of cell cycle gene expression in bone development and during c-Fos-induced osteosarcoma formation. Dev Genet. 1998;22(4):386-97 |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
Cdk11b cyclin dependent kinase 11B (Synonyms: Cdc2l1, Cdc2l2, CDK11-p110, CDK11-p46, CDK11-p58, PITSLRE proteins) | |
Results | Reference |
3* | J:40068 Kidd VJ, Luo W, Xiang JL, Tu F, Easton J, McCune S, Snead ML, Regulated expression of a cell division control-related protein kinase during development. Cell Growth Differ. 1991 Feb;2(2):85-93 |
Cdk12 cyclin dependent kinase 12 (Synonyms: 1810022J16Rik, Crk7, Crkrs, D11Ertd752e) | |
Results | Reference |
1* | J:217121 Chen HR, Lin GT, Huang CK, Fann MJ, Cdk12 and Cdk13 regulate axonal elongation through a common signaling pathway that modulates Cdk5 expression. Exp Neurol. 2014 Nov;261:10-21 |
Cdk13 cyclin dependent kinase 13 (Synonyms: 2310015O17Rik, Cdc2l5) | |
Results | Reference |
1* | J:217121 Chen HR, Lin GT, Huang CK, Fann MJ, Cdk12 and Cdk13 regulate axonal elongation through a common signaling pathway that modulates Cdk5 expression. Exp Neurol. 2014 Nov;261:10-21 |
1 | J:350438 Hampl M, Jandova N, Luskova D, Novakova M, Szotkowska T, Cada S, Prochazka J, Kohoutek J, Buchtova M, Early embryogenesis in CHDFIDD mouse model reveals facial clefts and altered cranial neurogenesis. Dis Model Mech. 2024 Jun 1;17(6) |
Cdk14 cyclin dependent kinase 14 (Synonyms: mKIAA0834, Pftk1) | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Cdkl3 cyclin dependent kinase like 3 (Synonyms: B230379H01Rik, MGC:28957) | |
Results | Reference |
1* | J:137359 Dubos A, Pannetier S, Hanauer A, Inactivation of the CDKL3 gene at 5q31.1 by a balanced t(X;5) translocation associated with nonspecific mild mental retardation. Am J Med Genet A. 2008 May 15;146A(10):1267-79 |
Cdkl5 cyclin dependent kinase like 5 (Synonyms: Stk9) | |
Results | Reference |
1* | J:142562 Rusconi L, Salvatoni L, Giudici L, Bertani I, Kilstrup-Nielsen C, Broccoli V, Landsberger N, CDKL5 expression is modulated during neuronal development and its subcellular distribution is tightly regulated by the C-terminal tail. J Biol Chem. 2008 Oct 31;283(44):30101-11 |
Cdkn1a cyclin dependent kinase inhibitor 1A
(Synonyms:
CAP20, CDKI, Cdkn1, CIP1, mda6, P21, p21Cip1, p21WAF, p21 | |
Results | Reference |
2 | J:46753 Bloch-Zupan A, Leveillard T, Gorry P, Fausser JL, Ruch JV, Expression of p21(WAF1/CIP1) during mouse odontogenesis. Eur J Oral Sci. 1998 Jan;106 Suppl 1:104-11 |
1 | J:175458 Bren-Mattison Y, Hausburg M, Olwin BB, Growth of limb muscle is dependent on skeletal-derived Indian hedgehog. Dev Biol. 2011 Aug 15;356(2):486-95 |
1* | J:166613 Cao H, Florez S, Amen M, Huynh T, Skobe Z, Baldini A, Amendt BA, Tbx1 regulates progenitor cell proliferation in the dental epithelium by modulating Pitx2 activation of p21. Dev Biol. 2010 Nov 15;347(2):289-300 |
2* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:179734 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS, Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Dev Dyn. 2012 Feb;241(2):303-14 |
1 | J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82 |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
1 | J:216295 Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC, FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. 2014 Nov 1;395(1):50-61 |
1 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:305202 Gualtieri A, Kyprianou N, Gregory LC, Vignola ML, Nicholson JG, Tan R, Inoue SI, Scagliotti V, Casado P, Blackburn J, Abollo-Jimenez F, Marinelli E, Besser REJ, Hogler W, Karen Temple I, Davies JH, Gagunashvili A, Robinson ICAF, Camper SA, Davis SW, Cutillas PR, Gevers EF, Aoki Y, Dattani MT, Gaston-Massuet C, Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans. Nat Commun. 2021 Apr 1;12(1):2028 |
1 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
1* | J:62578 Hettmann T, Barton K, Leiden JM, Microphthalmia due to p53-mediated apoptosis of anterior lens epithelial cells in mice lacking the CREB-2 transcription factor. Dev Biol. 2000 Jun 1;222(1):110-23 |
2 | J:214032 Ishida K, Yuge Y, Hanaoka M, Yasukawa M, Minami Y, Ogawa M, Masumoto KH, Shigeyoshi Y, Saito M, Tsuji T, Gadd45g regulates dental epithelial cell proliferation through p38 MAPK-mediated p21 expression. Genes Cells. 2013 Aug;18(8):660-71 |
1 | J:361142 Ke X, van Soldt B, Vlahos L, Zhou Y, Qian J, George J, Capdevila C, Glass I, Yan K, Califano A, Cardoso WV, Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate. Dev Cell. 2024 Dec 9; |
1 | J:51084 Keranen SV, Aberg T, Kettunen P, Thesleff I, Jernvall J, Association of developmental regulatory genes with the development of different molar tooth shapes in two species of rodents. Dev Genes Evol. 1998 Nov;208(9):477-86 |
1* | J:231259 Krill KT, Gurdziel K, Heaton JH, Simon DP, Hammer GD, Dicer deficiency reveals microRNAs predicted to control gene expression in the developing adrenal cortex. Mol Endocrinol. 2013 May;27(5):754-68 |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
1 | J:261049 Leone DP, Srinivasan K, Brakebusch C, McConnell SK, The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain. Dev Neurobiol. 2010 Aug;70(9):659-78 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1 | J:98518 Mantela J, Jiang Z, Ylikoski J, Fritzsch B, Zacksenhaus E, Pirvola U, The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear. Development. 2005 May;132(10):2377-88 |
1 | J:255932 Mario Gonzalez-Meljem J, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Neda Mousavy-Gharavy S, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Pedro Martinez-Barbera J, Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. Nat Commun. 2017 Nov 28;8(1):1819 |
1 | J:210514 Martinez P, Ferrara-Romeo I, Flores JM, Blasco MA, Essential role for the TRF2 telomere protein in adult skin homeostasis. Aging Cell. 2014 Aug;13(4):656-68 |
1 | J:185038 Martinez P, Flores JM, Blasco MA, 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response. J Cell Biol. 2012 Apr 16;197(2):283-300 |
1* | J:182715 Monahan P, Himes AD, Parfieniuk A, Raetzman LT, p21, an important mediator of quiescence during pituitary tumor formation, is dispensable for normal pituitary development during embryogenesis. Mech Dev. 2012 Jan-Feb;128(11-12):640-52 |
1 | J:97328 Nishio S, Hatano M, Nagata M, Horie S, Koike T, Tokuhisa T, Mochizuki T, Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation. J Clin Invest. 2005 Apr 1;115(4):910-918 |
1 | J:180027 Restivo G, Nguyen BC, Dziunycz P, Ristorcelli E, Ryan RJ, Ozuysal OY, Di Piazza M, Radtke F, Dixon MJ, Hofbauer GF, Lefort K, Dotto GP, IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes. EMBO J. 2011 Nov 16;30(22):4571-85 |
1 | J:321171 Safwan-Zaiter H, Wagner N, Michiels JF, Wagner KD, Dynamic Spatiotemporal Expression Pattern of the Senescence-Associated Factor p16Ink4a in Development and Aging. Cells. 2022 Feb 4;11(3) |
1* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1* | J:249296 Spiller CM, Wilhelm D, Koopman P, Retinoblastoma 1 protein modulates XY germ cell entry into G1/G0 arrest during fetal development in mice. Biol Reprod. 2010 Feb;82(2):433-43 |
1 | J:205284 Storer M, Mas A, Robert-Moreno A, Pecoraro M, Ortells MC, Di Giacomo V, Yosef R, Pilpel N, Krizhanovsky V, Sharpe J, Keyes WM, Senescence is a developmental mechanism that contributes to embryonic growth and patterning. Cell. 2013 Nov 21;155(5):1119-30 |
1 | J:186876 Sugiyama N, Tsukiyama T, Yamaguchi TP, Yokoyama T, The canonical Wnt signaling pathway is not involved in renal cyst development in the kidneys of inv mutant mice. Kidney Int. 2011 May;79(9):957-65 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
1 | J:211957 Tane S, Ikenishi A, Okayama H, Iwamoto N, Nakayama KI, Takeuchi T, CDK inhibitors, p21(Cip1) and p27(Kip1), participate in cell cycle exit of mammalian cardiomyocytes. Biochem Biophys Res Commun. 2014 Jan 17;443(3):1105-9 |
1 | J:333324 Tominaga K, Sakashita E, Kasashima K, Kuroiwa K, Nagao Y, Iwamori N, Endo H, Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells. Int J Mol Sci. 2023 Jan 20;24(3) |
1 | J:99501 Wang J, Ito T, Udaka N, Okudela K, Yazawa T, Kitamura H, PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung. Tissue Cell. 2005 Feb;37(1):25-35 |
1 | J:91704 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Wankell M, Werner S, Thesleff I, Modulation of activin/bone morphogenetic protein signaling by follistatin is required for the morphogenesis of mouse molar teeth. Dev Dyn. 2004 Sep;231(1):98-108 |
1 | J:94518 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Werner S, Thesleff I, Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation. Dev Cell. 2004 Nov;7(5):719-30 |
1 | J:339368 Yao F, Huang S, Liu J, Tan C, Xu M, Wang D, Huang M, Zhu Y, Huang X, He S, Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis. Cell Death Dis. 2023 Aug 23;14(8):543 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
1 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
Cdkn1b cyclin dependent kinase inhibitor 1B (Synonyms: p27, p27Kip1) | |
Results | Reference |
1* | J:108720 Berthet C, Klarmann KD, Hilton MB, Suh HC, Keller JR, Kiyokawa H, Kaldis P, Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation. Dev Cell. 2006 May;10(5):563-73 |
1 | J:54260 Beumer TL, Kiyokawa H, Roepers-Gajadien HL, van den Bos LA, Lock TM, Gademan IS, Rutgers DH, Koff A, de Rooij DG, Regulatory role of p27kip1 in the mouse and human testis. Endocrinology. 1999 Apr;140(4):1834-40 |
1 | J:83482 Chen P, Zindy F, Abdala C, Liu F, Li X, Roussel MF, Segil N, Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d. Nat Cell Biol. 2003 May;5(5):422-6 |
1 | J:124435 Dyer MA, Cepko CL, p27Kip1 and p57Kip2 regulate proliferation in distinct retinal progenitor cell populations. J Neurosci. 2001 Jun 15;21(12):4259-71 |
1 | J:216295 Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC, FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. 2014 Nov 1;395(1):50-61 |
1 | J:151321 Glickstein SB, Monaghan JA, Koeller HB, Jones TK, Ross ME, Cyclin D2 is critical for intermediate progenitor cell proliferation in the embryonic cortex. J Neurosci. 2009 Jul 29;29(30):9614-24 |
1 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
1 | J:180774 Grimsley-Myers CM, Sipe CW, Wu DK, Lu X, Redundant functions of Rac GTPases in inner ear morphogenesis. Dev Biol. 2012 Feb 15;362(2):172-86 |
1 | J:305202 Gualtieri A, Kyprianou N, Gregory LC, Vignola ML, Nicholson JG, Tan R, Inoue SI, Scagliotti V, Casado P, Blackburn J, Abollo-Jimenez F, Marinelli E, Besser REJ, Hogler W, Karen Temple I, Davies JH, Gagunashvili A, Robinson ICAF, Camper SA, Davis SW, Cutillas PR, Gevers EF, Aoki Y, Dattani MT, Gaston-Massuet C, Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans. Nat Commun. 2021 Apr 1;12(1):2028 |
1* | J:231673 Gustin SE, Hogg K, Stringer JM, Rastetter RH, Pelosi E, Miles DC, Sinclair AH, Wilhelm D, Western PS, WNT/beta-catenin and p27/FOXL2 differentially regulate supporting cell proliferation in the developing ovary. Dev Biol. 2016 Apr 15;412(2):250-60 |
1 | J:133208 Hammerle B, Elizalde C, Tejedor FJ, The spatio-temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrk1A in the developing mouse brain suggests distinct sequential roles in neuronal development. Eur J Neurosci. 2008 Mar;27(5):1061-74 |
1 | J:98458 Kiernan AE, Pelling AL, Leung KK, Tang AS, Bell DM, Tease C, Lovell-Badge R, Steel KP, Cheah KS, Sox2 is required for sensory organ development in the mammalian inner ear. Nature. 2005 Apr 21;434(7036):1031-5 |
1 | J:156489 Krentz AD, Murphy MW, Kim S, Cook MS, Capel B, Zhu R, Matin A, Sarver AL, Parker KL, Griswold MD, Looijenga LH, Bardwell VJ, Zarkower D, The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22323-8 |
1* | J:294282 Li L, Ruan X, Wen C, Chen P, Liu W, Zhu L, Xiang P, Zhang X, Wei Q, Hou L, Yin B, Yuan J, Qiang B, Shu P, Peng X, The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019 Jul 16;28(3):698-711.e5 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:203797 Maatouk DM, Mork L, Chassot AA, Chaboissier MC, Capel B, Disruption of mitotic arrest precedes precocious differentiation and transdifferentiation of pregranulosa cells in the perinatal Wnt4 mutant ovary. Dev Biol. 2013 Nov 15;383(2):295-306 |
2 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
1 | J:157341 Monahan P, Rybak S, Raetzman LT, The notch target gene HES1 regulates cell cycle inhibitor expression in the developing pituitary. Endocrinology. 2009 Sep;150(9):4386-94 |
1* | J:74094 Nagahama H, Hatakeyama S, Nakayama K, Nagata M, Tomita K, Nakayama K, Spatial and temporal expression patterns of the cyclin-dependent kinase (CDK) inhibitors p27Kip1 and p57Kip2 during mouse development. Anat Embryol (Berl). 2001 Feb;203(2):77-87 |
1 | J:286655 Sakamoto S, Tateya T, Omori K, Kageyama R, Id genes are required for morphogenesis and cellular patterning in the developing mammalian cochlea. Dev Biol. 2020 Apr 15;460(2):164-175 |
1 | J:261250 Siddam AD, Gautier-Courteille C, Perez-Campos L, Anand D, Kakrana A, Dang CA, Legagneux V, Mereau A, Viet J, Gross JM, Paillard L, Lachke SA, The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development. PLoS Genet. 2018 Mar;14(3):e1007278 |
1* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1* | J:249296 Spiller CM, Wilhelm D, Koopman P, Retinoblastoma 1 protein modulates XY germ cell entry into G1/G0 arrest during fetal development in mice. Biol Reprod. 2010 Feb;82(2):433-43 |
1 | J:343554 Sun Q, Li J, Ma J, Zheng Y, Ju R, Li X, Ren X, Huang L, Chen R, Tan X, Luo L, JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development. Invest Ophthalmol Vis Sci. 2023 Dec 1;64(15):15 |
1 | J:48539 Sunters A, McCluskey J, Grigoriadis AE, Control of cell cycle gene expression in bone development and during c-Fos-induced osteosarcoma formation. Dev Genet. 1998;22(4):386-97 |
1 | J:211957 Tane S, Ikenishi A, Okayama H, Iwamoto N, Nakayama KI, Takeuchi T, CDK inhibitors, p21(Cip1) and p27(Kip1), participate in cell cycle exit of mammalian cardiomyocytes. Biochem Biophys Res Commun. 2014 Jan 17;443(3):1105-9 |
1 | J:112461 Tang LS, Alger HM, Pereira FA, COUP-TFI controls Notch regulation of hair cell and support cell differentiation. Development. 2006 Sep;133(18):3683-93 |
2 | J:320759 Yamauchi Y, Nita A, Nishiyama M, Muto Y, Shimizu H, Nakatsumi H, Nakayama KI, Skp2 contributes to cell cycle progression in trophoblast stem cells and to placental development. Genes Cells. 2020 Jun;25(6):427-438 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
1* | J:136711 Zhao H, Yang T, Madakashira BP, Thiels CA, Bechtle CA, Garcia CM, Zhang H, Yu K, Ornitz DM, Beebe DC, Robinson ML, Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. Dev Biol. 2008 Jun 15;318(2):276-88 |
1 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
Cdkn1c cyclin dependent kinase inhibitor 1C (Synonyms: CDKI, Kip2, p57Kip2) | |
Results | Reference |
1 | J:188254 Budry L, Balsalobre A, Gauthier Y, Khetchoumian K, L'honore A, Vallette S, Brue T, Figarella-Branger D, Meij B, Drouin J, The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling. Genes Dev. 2012 Oct 15;26(20):2299-310 |
1* | J:171072 Carre A, Rachdi L, Tron E, Richard B, Castanet M, Schlumberger M, Bidart JM, Szinnai G, Polak M, Hes1 is required for appropriate morphogenesis and differentiation during mouse thyroid gland development. PLoS One. 2011;6(2):e16752 |
1 | J:223109 Choi JJ, Ting CT, Trogrlic L, Milevski SV, Familari M, Martinez G, de Iongh RU, A role for smoothened during murine lens and cornea development. PLoS One. 2014;9(9):e108037 |
1 | J:229227 Colasante G, Simonet JC, Calogero R, Crispi S, Sessa A, Cho G, Golden JA, Broccoli V, ARX regulates cortical intermediate progenitor cell expansion and upper layer neuron formation through repression of Cdkn1c. Cereb Cortex. 2015 Feb;25(2):322-35 |
2 | J:63217 Dyer MA, Cepko CL, p57(Kip2) regulates progenitor cell proliferation and amacrine interneuron development in the mouse retina. Development. 2000 Aug;127(16):3593-605 |
1 | J:202337 Estrada KD, Wang W, Retting KN, Chien CT, Elkhoury FF, Heuchel R, Lyons KM, Smad7 regulates terminal maturation of chondrocytes in the growth plate. Dev Biol. 2013 Oct 15;382(2):375-84 |
1 | J:79882 Fitzpatrick GV, Soloway PD, Higgins MJ, Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1. Nat Genet. 2002 Nov;32(3):426-31 |
1 | J:216295 Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC, FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. 2014 Nov 1;395(1):50-61 |
1 | J:305202 Gualtieri A, Kyprianou N, Gregory LC, Vignola ML, Nicholson JG, Tan R, Inoue SI, Scagliotti V, Casado P, Blackburn J, Abollo-Jimenez F, Marinelli E, Besser REJ, Hogler W, Karen Temple I, Davies JH, Gagunashvili A, Robinson ICAF, Camper SA, Davis SW, Cutillas PR, Gevers EF, Aoki Y, Dattani MT, Gaston-Massuet C, Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans. Nat Commun. 2021 Apr 1;12(1):2028 |
1 | J:146280 Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H, C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57. PLoS One. 2009;4(2):e4543 |
1* | J:141989 Kirjavainen A, Sulg M, Heyd F, Alitalo K, Yla-Herttuala S, Moroy T, Petrova TV, Pirvola U, Prox1 interacts with Atoh1 and Gfi1, and regulates cellular differentiation in the inner ear sensory epithelia. Dev Biol. 2008 Oct 1;322(1):33-45 |
1 | J:208421 Klimova L, Kozmik Z, Stage-dependent requirement of neuroretinal Pax6 for lens and retina development. Development. 2014 Mar;141(6):1292-302 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1* | J:239146 Mademtzoglou D, Alonso-Martin S, Chang TH, Bismuth K, Drayton-Libotte B, Aurade F, Relaix F, A p57 conditional mutant allele that allows tracking of p57-expressing cells. Genesis. 2017 Apr;55(4) |
2 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
1 | J:179730 Mairet-Coello G, Tury A, Van Buskirk E, Robinson K, Genestine M, Dicicco-Bloom E, p57KIP2 regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortex. Development. 2012 Feb;139(3):475-87 |
1 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
1 | J:178174 Matsumoto A, Susaki E, Onoyama I, Nakayama K, Hoshino M, Nakayama KI, Deregulation of the p57-E2F1-p53 axis results in nonobstructive hydrocephalus and cerebellar malformation in mice. Mol Cell Biol. 2011 Oct;31(20):4176-92 |
1 | J:157341 Monahan P, Rybak S, Raetzman LT, The notch target gene HES1 regulates cell cycle inhibitor expression in the developing pituitary. Endocrinology. 2009 Sep;150(9):4386-94 |
1 | J:318774 Monemdjou R, Vasheghani F, Fahmi H, Perez G, Blati M, Taniguchi N, Lotz M, St-Arnaud R, Pelletier JP, Martel-Pelletier J, Beier F, Kapoor M, Association of cartilage-specific deletion of peroxisome proliferator-activated receptor gamma with abnormal endochondral ossification and impaired cartilage growth and development in a murine model. Arthritis Rheum. 2012 May;64(5):1551-61 |
1* | J:74094 Nagahama H, Hatakeyama S, Nakayama K, Nagata M, Tomita K, Nakayama K, Spatial and temporal expression patterns of the cyclin-dependent kinase (CDK) inhibitors p27Kip1 and p57Kip2 during mouse development. Anat Embryol (Berl). 2001 Feb;203(2):77-87 |
2* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
1 | J:93878 Salas M, John R, Saxena A, Barton S, Frank D, Fitzpatrick G, Higgins MJ, Tycko B, Placental growth retardation due to loss of imprinting of Phlda2. Mech Dev. 2004 Oct;121(10):1199-210 |
1 | J:206876 Song JY, Park R, Kim JY, Hughes L, Lu L, Kim S, Johnson RL, Cho SH, Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev Biol. 2014 Feb 15;386(2):281-90 |
1* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1* | J:249296 Spiller CM, Wilhelm D, Koopman P, Retinoblastoma 1 protein modulates XY germ cell entry into G1/G0 arrest during fetal development in mice. Biol Reprod. 2010 Feb;82(2):433-43 |
1 | J:205284 Storer M, Mas A, Robert-Moreno A, Pecoraro M, Ortells MC, Di Giacomo V, Yosef R, Pilpel N, Krizhanovsky V, Sharpe J, Keyes WM, Senescence is a developmental mechanism that contributes to embryonic growth and patterning. Cell. 2013 Nov 21;155(5):1119-30 |
1 | J:154910 Sugiyama Y, Akimoto K, Robinson ML, Ohno S, Quinlan RA, A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol. 2009 Dec 15;336(2):246-56 |
1 | J:343554 Sun Q, Li J, Ma J, Zheng Y, Ju R, Li X, Ren X, Huang L, Chen R, Tan X, Luo L, JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development. Invest Ophthalmol Vis Sci. 2023 Dec 1;64(15):15 |
1 | J:211957 Tane S, Ikenishi A, Okayama H, Iwamoto N, Nakayama KI, Takeuchi T, CDK inhibitors, p21(Cip1) and p27(Kip1), participate in cell cycle exit of mammalian cardiomyocytes. Biochem Biophys Res Commun. 2014 Jan 17;443(3):1105-9 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
2 | J:232408 Van De Pette M, Tunster SJ, McNamara GI, Shelkovnikova T, Millership S, Benson L, Peirson S, Christian M, Vidal-Puig A, John RM, Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome. PLoS Genet. 2016 Mar;12(3):e1005916 |
2 | J:320759 Yamauchi Y, Nita A, Nishiyama M, Muto Y, Shimizu H, Nakatsumi H, Nakayama KI, Skp2 contributes to cell cycle progression in trophoblast stem cells and to placental development. Genes Cells. 2020 Jun;25(6):427-438 |
1* | J:136711 Zhao H, Yang T, Madakashira BP, Thiels CA, Bechtle CA, Garcia CM, Zhang H, Yu K, Ornitz DM, Beebe DC, Robinson ML, Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. Dev Biol. 2008 Jun 15;318(2):276-88 |
Cdkn2a cyclin dependent kinase inhibitor 2A
(Synonyms:
Arf, ARF-INK4a, Ink4a/Arf, INK4a-ARF, MTS1, p16, p16INK4a, p19 | |
Results | Reference |
1 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:305202 Gualtieri A, Kyprianou N, Gregory LC, Vignola ML, Nicholson JG, Tan R, Inoue SI, Scagliotti V, Casado P, Blackburn J, Abollo-Jimenez F, Marinelli E, Besser REJ, Hogler W, Karen Temple I, Davies JH, Gagunashvili A, Robinson ICAF, Camper SA, Davis SW, Cutillas PR, Gevers EF, Aoki Y, Dattani MT, Gaston-Massuet C, Activating mutations in BRAF disrupt the hypothalamo-pituitary axis leading to hypopituitarism in mice and humans. Nat Commun. 2021 Apr 1;12(1):2028 |
1 | J:192707 He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, Pu WT, Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res. 2012 Feb 3;110(3):406-15 |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
1 | J:255932 Mario Gonzalez-Meljem J, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Neda Mousavy-Gharavy S, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Pedro Martinez-Barbera J, Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. Nat Commun. 2017 Nov 28;8(1):1819 |
2 | J:321171 Safwan-Zaiter H, Wagner N, Michiels JF, Wagner KD, Dynamic Spatiotemporal Expression Pattern of the Senescence-Associated Factor p16Ink4a in Development and Aging. Cells. 2022 Feb 4;11(3) |
1* | J:249296 Spiller CM, Wilhelm D, Koopman P, Retinoblastoma 1 protein modulates XY germ cell entry into G1/G0 arrest during fetal development in mice. Biol Reprod. 2010 Feb;82(2):433-43 |
1 | J:205284 Storer M, Mas A, Robert-Moreno A, Pecoraro M, Ortells MC, Di Giacomo V, Yosef R, Pilpel N, Krizhanovsky V, Sharpe J, Keyes WM, Senescence is a developmental mechanism that contributes to embryonic growth and patterning. Cell. 2013 Nov 21;155(5):1119-30 |
1 | J:48539 Sunters A, McCluskey J, Grigoriadis AE, Control of cell cycle gene expression in bone development and during c-Fos-induced osteosarcoma formation. Dev Genet. 1998;22(4):386-97 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
1 | J:225537 Zhang J, Taylor RJ, La Torre A, Wilken MS, Cox KE, Reh TA, Vetter ML, Ezh2 maintains retinal progenitor proliferation, transcriptional integrity, and the timing of late differentiation. Dev Biol. 2015 Jul 15;403(2):128-38 |
1 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
Cdkn2b cyclin dependent kinase inhibitor 2B (Synonyms: MTS2, p15, p15INK4b) | |
Results | Reference |
1 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:192707 He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, Pu WT, Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res. 2012 Feb 3;110(3):406-15 |
1 | J:184521 Koss M, Bolze A, Brendolan A, Saggese M, Capellini TD, Bojilova E, Boisson B, Prall OW, Elliott DA, Solloway M, Lenti E, Hidaka C, Chang CP, Mahlaoui N, Harvey RP, Casanova JL, Selleri L, Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module. Dev Cell. 2012 May 15;22(5):913-26 |
1* | J:249296 Spiller CM, Wilhelm D, Koopman P, Retinoblastoma 1 protein modulates XY germ cell entry into G1/G0 arrest during fetal development in mice. Biol Reprod. 2010 Feb;82(2):433-43 |
1 | J:205284 Storer M, Mas A, Robert-Moreno A, Pecoraro M, Ortells MC, Di Giacomo V, Yosef R, Pilpel N, Krizhanovsky V, Sharpe J, Keyes WM, Senescence is a developmental mechanism that contributes to embryonic growth and patterning. Cell. 2013 Nov 21;155(5):1119-30 |
Cdkn2c cyclin dependent kinase inhibitor 2C (Synonyms: INK4c, p18, p18INK4c) | |
Results | Reference |
1 | J:216295 Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC, FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. 2014 Nov 1;395(1):50-61 |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
Cdkn2d cyclin dependent kinase inhibitor 2D (Synonyms: INK4d, INK4d, p19, p19INK4d) | |
Results | Reference |
1 | J:83482 Chen P, Zindy F, Abdala C, Liu F, Li X, Roussel MF, Segil N, Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d. Nat Cell Biol. 2003 May;5(5):422-6 |
1 | J:166789 Dong Y, Sui L, Yamaguchi F, Kamitori K, Hirata Y, Hossain MA, Suzuki A, Holley MC, Tokuda M, Phosphatase and tensin homolog deleted on chromosome 10 regulates sensory cell proliferation and differentiation of hair bundles in the mammalian cochlea. Neuroscience. 2010 Nov 10;170(4):1304-13 |
1 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
1 | J:321171 Safwan-Zaiter H, Wagner N, Michiels JF, Wagner KD, Dynamic Spatiotemporal Expression Pattern of the Senescence-Associated Factor p16Ink4a in Development and Aging. Cells. 2022 Feb 4;11(3) |
1 | J:205284 Storer M, Mas A, Robert-Moreno A, Pecoraro M, Ortells MC, Di Giacomo V, Yosef R, Pilpel N, Krizhanovsky V, Sharpe J, Keyes WM, Senescence is a developmental mechanism that contributes to embryonic growth and patterning. Cell. 2013 Nov 21;155(5):1119-30 |
1 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
Cdon cell adhesion molecule-related/down-regulated by oncogenes (Synonyms: CAM-related/down-regulated by oncogenes, CDO) | |
Results | Reference |
1* | J:267598 Castiglioni I, Caccia R, Garcia-Manteiga JM, Ferri G, Caretti G, Molineris I, Nishioka K, Gabellini D, The Trithorax protein Ash1L promotes myoblast fusion by activating Cdon expression. Nat Commun. 2018 Nov 28;9(1):5026 |
2 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1* | J:82221 Cole F, Krauss RS, Microform Holoprosencephaly in Mice that Lack the Ig Superfamily Member Cdon. Curr Biol. 2003 Mar 4;13(5):411-5 |
1 | J:304642 Dupacova N, Antosova B, Paces J, Kozmik Z, Meis homeobox genes control progenitor competence in the retina. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2013136118 |
1 | J:346064 Leung AOW, Poon ACH, Wang X, Feng C, Chen P, Zheng Z, To MK, Chan WCW, Cheung M, Chan D, Suppression of apoptosis impairs phalangeal joint formation in the pathogenesis of brachydactyly type A1. Nat Commun. 2024 Mar 12;15(1):2229 |
1 | J:109070 Zhang W, Yi MJ, Chen X, Cole F, Krauss RS, Kang JS, Cortical thinning and hydrocephalus in mice lacking the immunoglobulin superfamily member CDO. Mol Cell Biol. 2006 May;26(10):3764-72 |
Cdsn corneodesmosin | |
Results | Reference |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
1 | J:182938 Sevilla LM, Bayo P, Latorre V, Sanchis A, Perez P, Glucocorticoid receptor regulates overlapping and differential gene subsets in developing and adult skin. Mol Endocrinol. 2010 Nov;24(11):2166-78 |
Cdx1 caudal type homeobox 1 (Synonyms: Cdx, Cdx-1) | |
Results | Reference |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1* | J:9557 Duprey P, Chowdhury K, Dressler GR, Balling R, Simon D, Guenet JL, Gruss P, A mouse gene homologous to the Drosophila gene caudal is expressed in epithelial cells from the embryonic intestine. Genes Dev. 1988 Dec;2(12A):1647-54 |
1 | J:164807 Joo JH, Taxter TJ, Munguba GC, Kim YH, Dhaduvai K, Dunn NW, Degan WJ, Oh SP, Sugrue SP, Pinin modulates expression of an intestinal homeobox gene, Cdx2, and plays an essential role for small intestinal morphogenesis. Dev Biol. 2010 Sep 15;345(2):191-203 |
Cdx2 caudal type homeobox 2 (Synonyms: Cdx-2) | |
Results | Reference |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1 | J:164807 Joo JH, Taxter TJ, Munguba GC, Kim YH, Dhaduvai K, Dunn NW, Degan WJ, Oh SP, Sugrue SP, Pinin modulates expression of an intestinal homeobox gene, Cdx2, and plays an essential role for small intestinal morphogenesis. Dev Biol. 2010 Sep 15;345(2):191-203 |
1* | J:275007 Kumar N, Tsai YH, Chen L, Zhou A, Banerjee KK, Saxena M, Huang S, Toke NH, Xing J, Shivdasani RA, Spence JR, Verzi MP, The lineage-specific transcription factor CDX2 navigates dynamic chromatin to control distinct stages of intestine development. Development. 2019 Mar 1;146(5):dev172189 |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
1 | J:65118 Silberg DG, Swain GP, Suh ER, Traber PG, Cdx1 and cdx2 expression during intestinal development. Gastroenterology. 2000 Oct;119(4):961-71 |
Ceacam1 CEA cell adhesion molecule 1 (Synonyms: Bgp, Bgp1, Cc1, C-CAM, CD66a, Cea-1, Cea1, Cea-7, Cea7, Hv-2, Hv2, mCEA1, Mhv-1, MHVR1, mmCGM1, mmCGM2) | |
Results | Reference |
1* | J:33703 Daniels E, Letourneau S, Turbide C, Kuprina N, Rudinskaya T, Yazova AC, Holmes KV, Dveksler GS, Beauchemin N, Biliary glycoprotein 1 expression during embryogenesis: correlation with events of epithelial differentiation, mesenchymal-epithelial interactions, absorption, and myogenesis. Dev Dyn. 1996 Jul;206(3):272-90 |
1* | J:32555 Huang JQ, Turbide C, Daniels E, Jothy S, Beauchemin N, Spatiotemporal expression of murine carcinoembryonic antigen (CEA) gene family members during mouse embryogenesis. Development. 1990 Oct;110(2):573-88 |
1 | J:222173 Solano ME, Kowal MK, O'Rourke GE, Horst AK, Modest K, Plosch T, Barikbin R, Remus CC, Berger RG, Jago C, Ho H, Sass G, Parker VJ, Lydon JP, DeMayo FJ, Hecher K, Karimi K, Arck PC, Progesterone and HMOX-1 promote fetal growth by CD8+ T cell modulation. J Clin Invest. 2015 Apr;125(4):1726-38 |
Ceacam9 CEA cell adhesion molecule 9 (Synonyms: Cea-5, Cea5, mmCGM8) | |
Results | Reference |
1* | J:81004 Finkenzeller D, Fischer B, Lutz S, Schrewe H, Shimizu T, Zimmermann W, Carcinoembryonic antigen-related cell adhesion molecule 10 expressed specifically early in pregnancy in the decidua is dispensable for normal murine development. Mol Cell Biol. 2003 Jan;23(1):272-9 |
Ceacam10 CEA cell adhesion molecule 10 (Synonyms: Bgp3, Cea10) | |
Results | Reference |
1* | J:81004 Finkenzeller D, Fischer B, Lutz S, Schrewe H, Shimizu T, Zimmermann W, Carcinoembryonic antigen-related cell adhesion molecule 10 expressed specifically early in pregnancy in the decidua is dispensable for normal murine development. Mol Cell Biol. 2003 Jan;23(1):272-9 |
1* | J:199706 Li SH, Lee RK, Hsiao YL, Chen YH, Demonstration of a glycoprotein derived from the Ceacam10 gene in mouse seminal vesicle secretions. Biol Reprod. 2005 Sep;73(3):546-53 |
Ceacam11 CEA cell adhesion molecule 11 (Synonyms: 1600015D01Rik, Ceacam11-C1, Ceacam11-C3, Ceacam11-C4) | |
Results | Reference |
1* | J:75062 Kataoka K, Takata Y, Nakajima A, Saito S, Huh N, A carcinoembryonic antigen family cDNA from mouse placenta encoding a protein with a rare domain composition. Placenta. 2000 Sep;21(7):610-4 |
Cebpa CCAAT/enhancer binding protein alpha (Synonyms: Cebp, C/ebpalpha, C/EBP alpha) | |
Results | Reference |
1 | J:200565 Antony N, Weir JR, McDougall AR, Mantamadiotis T, Meikle PJ, Cole TJ, Bird AD, cAMP response element binding protein1 is essential for activation of steroyl co-enzyme a desaturase 1 (Scd1) in mouse lung type II epithelial cells. PLoS One. 2013;8(4):e59763 |
1 | J:89611 Asaki T, Konishi M, Miyake A, Kato S, Tomizawa M, Itoh N, Roles of fibroblast growth factor 10 (Fgf10) in adipogenesis in vivo. Mol Cell Endocrinol. 2004 Apr 15;218(1-2):119-28 |
1 | J:121202 Berg T, Didon L, Nord M, Ectopic expression of C/EBPalpha in the lung epithelium disrupts late lung development. Am J Physiol Lung Cell Mol Physiol. 2006 Oct;291(4):L683-93 |
1 | J:180979 Besnard V, Wert SE, Ikegami M, Xu Y, Heffner C, Murray SA, Donahue LR, Whitsett JA, Maternal synchronization of gestational length and lung maturation. PLoS One. 2011;6(11):e26682 |
1* | J:76945 Carmona MC, Iglesias R, Obregon MJ, Darlington GJ, Villarroya F, Giralt M, Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein alpha. J Biol Chem. 2002 Jun 14;277(24):21489-98 |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
1* | J:348284 Hassan D, Chen J, CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair. Nat Commun. 2024 May 16;15(1):4148 |
2* | J:239792 Hong KY, Bae H, Park I, Park DY, Kim KH, Kubota Y, Cho ES, Kim H, Adams RH, Yoo OJ, Koh GY, Perilipin+ embryonic preadipocytes actively proliferate along growing vasculatures for adipose expansion. Development. 2015 Aug 01;142(15):2623-32 |
1* | J:89458 Jochheim A, Hillemann T, Kania G, Scharf J, Attaran M, Manns MP, Wobus AM, Ott M, Quantitative gene expression profiling reveals a fetal hepatic phenotype of murine ES-derived hepatocytes. Int J Dev Biol. 2004 Feb;48(1):23-9 |
1* | J:331303 Kantzer CG, Yang W, Grommisch D, Patikl KV, Mak KH, Shirokova V, Genander M, ID1 and CEBPA coordinate epidermal progenitor cell differentiation. Development. 2022 Nov;149(22) |
1 | J:32954 Kuo CF, Xanthopoulos KG, Darnell JE Jr, Fetal and adult localization of C/EBP: evidence for combinatorial action of transcription factors in cell-specific gene expression. Development. 1990 Jun;109(2):473-81 |
1 | J:111670 Kyrmizi I, Hatzis P, Katrakili N, Tronche F, Gonzalez FJ, Talianidis I, Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev. 2006 Aug 15;20(16):2293-305 |
2 | J:237343 Laresgoiti U, Nikolic MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL, Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016 Oct 15;143(20):3686-3699 |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
1* | J:46862 Oesterreicher TJ, Leeper LL, Finegold MJ, Darlington GJ, Henning SJ, Intestinal maturation in mice lacking CCAAT/enhancer-binding protein alpha (C/EPBalpha). Biochem J. 1998 Mar 15;330(Pt 3):1165-71 |
1* | J:141842 Tomita T, Kido T, Kurotani R, Iemura S, Sterneck E, Natsume T, Vinson C, Kimura S, CAATT/enhancer-binding proteins alpha and delta interact with NKX2-1 to synergistically activate mouse secretoglobin 3A2 gene expression. J Biol Chem. 2008 Sep 12;283(37):25617-27 |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
1 | J:114400 Yamasaki H, Sada A, Iwata T, Niwa T, Tomizawa M, Xanthopoulos KG, Koike T, Shiojiri N, Suppression of C/EBP{alpha} expression in periportal hepatoblasts may stimulate biliary cell differentiation through increased Hnf6 and Hnf1b expression. Development. 2006 Nov;133(21):4233-43 |
1* | J:272566 Yang R, Wang H, Kang B, Chen B, Shi Y, Yang S, Sun L, Liu Y, Xiao W, Zhang T, Yang J, Zhang Y, Zhu M, Xu P, Chang Y, Jia Y, Huang Y, CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235 |
Cebpb CCAAT/enhancer binding protein beta (Synonyms: C/EBPbeta, C/EBP BETA, CRP2, IL-6DBP, LAP, LIP, Nfil6, NF-IL6, NF-M) | |
Results | Reference |
1 | J:89611 Asaki T, Konishi M, Miyake A, Kato S, Tomizawa M, Itoh N, Roles of fibroblast growth factor 10 (Fgf10) in adipogenesis in vivo. Mol Cell Endocrinol. 2004 Apr 15;218(1-2):119-28 |
1* | J:76945 Carmona MC, Iglesias R, Obregon MJ, Darlington GJ, Villarroya F, Giralt M, Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein alpha. J Biol Chem. 2002 Jun 14;277(24):21489-98 |
1 | J:146280 Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H, C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57. PLoS One. 2009;4(2):e4543 |
1* | J:239792 Hong KY, Bae H, Park I, Park DY, Kim KH, Kubota Y, Cho ES, Kim H, Adams RH, Yoo OJ, Koh GY, Perilipin+ embryonic preadipocytes actively proliferate along growing vasculatures for adipose expansion. Development. 2015 Aug 01;142(15):2623-32 |
1* | J:46862 Oesterreicher TJ, Leeper LL, Finegold MJ, Darlington GJ, Henning SJ, Intestinal maturation in mice lacking CCAAT/enhancer-binding protein alpha (C/EPBalpha). Biochem J. 1998 Mar 15;330(Pt 3):1165-71 |
1* | J:209518 Ushijima T, Okazaki K, Tsushima H, Iwamoto Y, CCAAT/enhancer-binding protein beta regulates the repression of type II collagen expression during the differentiation from proliferative to hypertrophic chondrocytes. J Biol Chem. 2014 Jan 31;289(5):2852-63 |
Cebpd CCAAT/enhancer binding protein delta | |
Results | Reference |
1* | J:76945 Carmona MC, Iglesias R, Obregon MJ, Darlington GJ, Villarroya F, Giralt M, Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein alpha. J Biol Chem. 2002 Jun 14;277(24):21489-98 |
1 | J:146280 Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H, C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57. PLoS One. 2009;4(2):e4543 |
1* | J:46862 Oesterreicher TJ, Leeper LL, Finegold MJ, Darlington GJ, Henning SJ, Intestinal maturation in mice lacking CCAAT/enhancer-binding protein alpha (C/EPBalpha). Biochem J. 1998 Mar 15;330(Pt 3):1165-71 |
1* | J:76819 Porter D, Lahti-Domenici J, Torres-Arzayus M, Chin L, Polyak K, Expression of high in normal-1 (HIN-1) and uteroglobin related protein-1 (UGRP-1) in adult and developing tissues. Mech Dev. 2002 Jun;114(1-2):201 |
1* | J:141842 Tomita T, Kido T, Kurotani R, Iemura S, Sterneck E, Natsume T, Vinson C, Kimura S, CAATT/enhancer-binding proteins alpha and delta interact with NKX2-1 to synergistically activate mouse secretoglobin 3A2 gene expression. J Biol Chem. 2008 Sep 12;283(37):25617-27 |
Cecr2 CECR2, histone acetyl-lysine reader (Synonyms: 2610101O16Rik, 2810409N01Rik, cat eye syndrome chromosome region, candidate 2, Gtl4, mKIAA1740) | |
Results | Reference |
1* | J:197015 Thompson PJ, Norton KA, Niri FH, Dawe CE, McDermid HE, CECR2 is involved in spermatogenesis and forms a complex with SNF2H in the testis. J Mol Biol. 2012 Feb 3;415(5):793-806 |
Cela1 chymotrypsin-like elastase family, member 1 (Synonyms: 1810009A17Rik, 1810062B19Rik, Ela-1, Ela1, PC-TsF) | |
Results | Reference |
1 | J:125691 Masui T, Long Q, Beres TM, Magnuson MA, Macdonald RJ, Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex. Genes Dev. 2007 Oct 15;21(20):2629-43 |
1 | J:119908 Wells JM, Esni F, Boivin GP, Aronow BJ, Stuart W, Combs C, Sklenka A, Leach SD, Lowy AM, Wnt/beta-catenin signaling is required for development of the exocrine pancreas. BMC Dev Biol. 2007;7:4 |
Cela2a chymotrypsin-like elastase family, member 2A (Synonyms: Ela-2, Ela2, Ela2a) | |
Results | Reference |
2* | J:50645 Petrucco S, Wellauer PK, Hagenbuchle O, The DNA-binding activity of transcription factor PTF1 parallels the synthesis of pancreas-specific mRNAs during mouse development. Mol Cell Biol. 1990 Jan;10(1):254-64 |
Celf1 CUGBP, Elav-like family member 1 (Synonyms: 1600010O03Rik, Brunol2, CUG-BP, Cugbp1, CUG-BP1, D2Wsu101e) | |
Results | Reference |
1 | J:261250 Siddam AD, Gautier-Courteille C, Perez-Campos L, Anand D, Kakrana A, Dang CA, Legagneux V, Mereau A, Viet J, Gross JM, Paillard L, Lachke SA, The RNA-binding protein Celf1 post-transcriptionally regulates p27Kip1 and Dnase2b to control fiber cell nuclear degradation in lens development. PLoS Genet. 2018 Mar;14(3):e1007278 |
Celf3 CUGBP, Elav-like family member 3 (Synonyms: 4930415M08Rik, BRUNOL1, CAGH4, ERDA4, Tnrc4) | |
Results | Reference |
1 | J:230219 Ishizuka A, Hasegawa Y, Ishida K, Yanaka K, Nakagawa S, Formation of nuclear bodies by the lncRNA Gomafu-associating proteins Celf3 and SF1. Genes Cells. 2014 Sep;19(9):704-21 |
Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 (Synonyms: Adgrc1, crash, Crsh, Scy) | |
Results | Reference |
1 | J:264107 Ghimire SR, Ratzan EM, Deans MR, A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea. Development. 2018 Jun 14;145(12):dev159012 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1 | J:348633 Paramore SV, Trenado-Yuste C, Sharan R, Nelson CM, Devenport D, Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation. Dev Cell. 2024 May 20;59(10):1302-1316.e5 |
Celsr2 cadherin, EGF LAG seven-pass G-type receptor 2 (Synonyms: Adgrc2, EGFL2, flamingo, mfmi1) | |
Results | Reference |
1 | J:212241 Boutin C, Labedan P, Dimidschstein J, Richard F, Cremer H, Andre P, Yang Y, Montcouquiol M, Goffinet AM, Tissir F, A dual role for planar cell polarity genes in ciliated cells. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):E3129-38 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
Celsr3 cadherin, EGF LAG seven-pass G-type receptor 3 (Synonyms: Adgrc3, flamingo, Fmi1, mKIAA0812) | |
Results | Reference |
1 | J:264107 Ghimire SR, Ratzan EM, Deans MR, A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea. Development. 2018 Jun 14;145(12):dev159012 |
1 | J:197538 Sasselli V, Boesmans W, Vanden Berghe P, Tissir F, Goffinet AM, Pachnis V, Planar cell polarity genes control the connectivity of enteric neurons. J Clin Invest. 2013 Apr 1;123(4):1763-72 |
Cemip2 cell migration inducing hyaluronidase 2 (Synonyms: 3110012M15Rik, mKIAA1412, Tmem2) | |
Results | Reference |
1* | J:346912 Huang H, Hu X, Wu J, Song C, Tian Z, Jiang B, Hyaluronan degradation by HYAL2 is essential for odontoblastic differentiation and migration of mouse dental papilla cells. Matrix Biol. 2024 Mar 13; |
1* | J:341326 Nag P, Inubushi T, Sasaki JI, Murotani T, Kusano S, Nakanishi Y, Shiraishi Y, Kurosaka H, Imazato S, Yamaguchi Y, Yamashiro T, Tmem2 Deficiency Leads to Enamel Hypoplasia and Soft Enamel in Mouse. J Dent Res. 2023 Sep;102(10):1162-1171 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Cend1 cell cycle exit and neuronal differentiation 1 (Synonyms: 1500001H12Rik, BM88) | |
Results | Reference |
1* | J:101287 Koutmani Y, Hurel C, Patsavoudi E, Hack M, Gotz M, Thomaidou D, Matsas R, BM88 is an early marker of proliferating precursor cells that will differentiate into the neuronal lineage. Eur J Neurosci. 2004 Nov;20(10):2509-23 |
Cenpa centromere protein A (Synonyms: Cenp-A, centrosomin A) | |
Results | Reference |
1* | J:347585 Leon NY, Le TNU, Garvie A, Wong LH, Bagheri-Fam S, Harley VR, Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. iScience. 2024 May 17;27(5):109629 |
1* | J:242348 Soh YQS, Mikedis MM, Kojima M, Godfrey AK, de Rooij DG, Page DC, Meioc maintains an extended meiotic prophase I in mice. PLoS Genet. 2017 Apr;13(4):e1006704 |
Cenpf centromere protein F (Synonyms: 6530404A22Rik, Lek1, mitosin) | |
Results | Reference |
2* | J:55850 Goodwin RL, Pabon-Pena LM, Foster GC, Bader D, The cloning and analysis of LEK1 identifies variations in the LEK/centromere protein F/mitosin gene family. J Biol Chem. 1999 Jun 25;274(26):18597-604 |
2 | J:290729 Grundl M, Walz S, Hauf L, Schwab M, Werner KM, Spahr S, Schulte C, Maric HM, Ade CP, Gaubatz S, Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes. PLoS Genet. 2020 May;16(5):e1008818 |
Cep43 centrosomal protein 43 (Synonyms: 4930553O10Rik, Fgfr1op, Fop) | |
Results | Reference |
1* | J:265810 Cabaud O, Roubin R, Comte A, Bascunana V, Serge A, Sedjai F, Birnbaum D, Rosnet O, Acquaviva C, Mutation of FOP/FGFR1OP in mice recapitulates human short rib-polydactyly ciliopathy. Hum Mol Genet. 2018 Oct 1;27(19):3377-3391 |
Cep55 centrosomal protein 55 (Synonyms: 1200008O12Rik, 2700032M20Rik) | |
Results | Reference |
1 | J:314161 Rashidieh B, Shohayeb B, Bain AL, Fortuna PRJ, Sinha D, Burgess A, Mills R, Adams RC, Lopez JA, Blumbergs P, Finnie J, Kalimutho M, Piper M, Hudson JE, Ng DCH, Khanna KK, Cep55 regulation of PI3K/Akt signaling is required for neocortical development and ciliogenesis. PLoS Genet. 2021 Oct;17(10):e1009334 |
1 | J:287102 Tedeschi A, Almagro J, Renshaw MJ, Messal HA, Behrens A, Petronczki M, Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions. Nat Commun. 2020 Apr 8;11(1):1746 |
Cep97 centrosomal protein 97 (Synonyms: 2810403B08Rik, 4932439K18Rik, E130116N02Rik, Lrriq2) | |
Results | Reference |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
Cep120 centrosomal protein 120 (Synonyms: Ccdc100) | |
Results | Reference |
1 | J:126953 Xie Z, Moy LY, Sanada K, Zhou Y, Buchman JJ, Tsai LH, Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool. Neuron. 2007 Oct 4;56(1):79-93 |
Cep135 centrosomal protein 135 (Synonyms: Cep4, LOC381644, MGC:86039) | |
Results | Reference |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
Cep192 centrosomal protein 192 (Synonyms: 4631422C13Rik, D430014P18Rik) | |
Results | Reference |
1 | J:338889 Siguero-Alvarez M, Salguero-Jimenez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sanchez-Saez F, Pineiro-Sabaris R, Felipe-Medina N, Torroja C, Gomez MJ, Sabater-Molina M, Escriba R, Richaud-Patin I, Iglesias-Garcia O, Sbroggio M, Callejas S, O'Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibanez B, Monserrat L, Perez-Pomares JM, Sanchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL, A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation. 2023 Jan 3;147(1):47-65 |
Cer1 cerberus 1, DAN family BMP antagonist (Synonyms: cer-1, Cerberus-like, Cerl, Cerl1, Cerr1) | |
Results | Reference |
1 | J:73145 Lu MM, Yang H, Zhang L, Shu W, Blair DG, Morrisey EE, The bone morphogenic protein antagonist gremlin regulates proximal-distal patterning of the lung. Dev Dyn. 2001 Dec;222(4):667-80 |
Cers1 ceramide synthase 1 (Synonyms: CerS1, Lass1, to, Uog-1) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Cers2 ceramide synthase 2 (Synonyms: 0610013I17Rik, CerS2, Lass2, Trh3) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Cers3 ceramide synthase 3 (Synonyms: 4930550L11Rik, CerS3, Lass3, LOC233330, related to TRH3, T3L) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Cers4 ceramide synthase 4 (Synonyms: 2900019C14Rik, CerS4, Lass4, Trh1) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Cers5 ceramide synthase 5 (Synonyms: 2310081H14Rik, CerS5, Lass5, Trh4) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Cers6 ceramide synthase 6 (Synonyms: 4732462C07Rik, CerS6, Lass6, similar to TRH1, T1L) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Ces1d carboxylesterase 1D (Synonyms: Ces3, TGH) | |
Results | Reference |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Cetn3 centrin 3 (Synonyms: MmCEN3) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Cfap20 cilia and flagella associated protein 20 (Synonyms: 2600014O15Rik, Gtl3, T10-2A2) | |
Results | Reference |
1* | J:34146 Rijkers T, Ruther U, Sequence and expression pattern of an evolutionarily conserved transcript identified by gene trapping. Biochim Biophys Acta. 1996 Jul 17;1307(3):294-300 |
Cfap43 cilia and flagella associated protein 43 (Synonyms: 4632415N18Rik, 4930428C11Rik, 4930463G05Rik, D19Ertd652e, Wdr96) | |
Results | Reference |
1 | J:286555 Rachev E, Schuster-Gossler K, Fuhl F, Ott T, Tveriakhina L, Beckers A, Hegermann J, Boldt K, Mai M, Kremmer E, Ueffing M, Blum M, Gossler A, CFAP43 modulates ciliary beating in mouse and Xenopus. Dev Biol. 2020 Mar 15;459(2):109-125 |
Cfap52 cilia and flagella associated protein 52 (Synonyms: 1700019F09Rik, 4933417B11Rik, Wdr16) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Cfap53 cilia and flagella associated protein 53 (Synonyms: 4933415I03Rik, Ccdc11) | |
Results | Reference |
2 | J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6 |
Cfap92 cilia and flagella associated protein 92 (Synonyms: 1810020O05Rik) | |
Results | Reference |
1* | J:99372 van der Zwaag B, Burbach JP, Scharfe C, Oefner PJ, Brunner HG, Padberg GW, van Bokhoven H, Identifying new candidate genes for hereditary facial paresis on chromosome 3q21-q22 by RNA in situ hybridization in mouse. Genomics. 2005 Jul;86(1):55-67 |
Cfap100 cilia and flagella associated protein 100 (Synonyms: C030041G11Rik, C230069K22Rik, Ccdc37) | |
Results | Reference |
1* | J:99372 van der Zwaag B, Burbach JP, Scharfe C, Oefner PJ, Brunner HG, Padberg GW, van Bokhoven H, Identifying new candidate genes for hereditary facial paresis on chromosome 3q21-q22 by RNA in situ hybridization in mouse. Genomics. 2005 Jul;86(1):55-67 |
Cfap144 cilia and flagella associated protein 144 (Synonyms: 3100002J23Rik, Fam183b) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Cfap161 cilia and flagella associated protein 161 (Synonyms: 1700026D08Rik) | |
Results | Reference |
2* | J:307371 Beckers A, Fuhl F, Ott T, Boldt K, Brislinger MM, Walentek P, Schuster-Gossler K, Hegermann J, Alten L, Kremmer E, Przykopanski A, Serth K, Ueffing M, Blum M, Gossler A, The highly conserved FOXJ1 target CFAP161 is dispensable for motile ciliary function in mouse and Xenopus. Sci Rep. 2021 Jun 25;11(1):13333 |
Cfap206 cilia and flagella associated protein 206 (Synonyms: 1700003M02Rik) | |
Results | Reference |
1* | J:293391 Beckers A, Adis C, Schuster-Gossler K, Tveriakhina L, Ott T, Fuhl F, Hegermann J, Boldt K, Serth K, Rachev E, Alten L, Kremmer E, Ueffing M, Blum M, Gossler A, The FOXJ1 target Cfap206 is required for sperm motility, mucociliary clearance of the airways and brain development. Development. 2020 Jun 15;147(21):dev188052 |
Cfh complement component factor h (Synonyms: Mud-1, Sas-1, Sas1) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Cfl1 cofilin 1, non-muscle (Synonyms: Cof, cofilin, n-cofilin) | |
Results | Reference |
1* | J:96452 Gurniak CB, Perlas E, Witke W, The actin depolymerizing factor n-cofilin is essential for neural tube morphogenesis and neural crest cell migration. Dev Biol. 2005 Feb 1;278(1):231-41 |
1* | J:314903 Jiang X, Lv J, Zhou R, Xiang X, The effect of cofilin 1 expression and phosphorylation dynamics on cell fate determination and neuron maturation in neural stem cells. Neurosci Lett. 2021 Nov 1;764:136292 |
1* | J:157948 Jiang XS, Wassif CA, Backlund PS, Song L, Holtzclaw LA, Li Z, Yergey AL, Porter FD, Activation of Rho GTPases in Smith-Lemli-Opitz syndrome: pathophysiological and clinical implications. Hum Mol Genet. 2010 Apr 1;19(7):1347-57 |
1 | J:311844 Landin MA, Nygard S, Shabestari MG, Babaie E, Reseland JE, Osmundsen H, Mapping the global mRNA transcriptome during development of the murine first molar. Front Genet. 2015;6:47 |
1* | J:235617 Xiang X, Li S, Zhuang X, Shi L, Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways. FEBS Lett. 2016 Sep;590(17):2940-55 |
Cftr cystic fibrosis transmembrane conductance regulator (Synonyms: Abcc7) | |
Results | Reference |
3 | J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005 |
Cga glycoprotein hormones, alpha subunit (Synonyms: aGSU, alpha-GSU, alphaGSU, alphaSU, GPHalpha, Tsha) | |
Results | Reference |
1 | J:30290 Andersen B, Pearse RV 2nd, Jenne K, Sornson M, Lin SC, Bartke A, Rosenfeld MG, The Ames dwarf gene is required for Pit-1 gene activation. Dev Biol. 1995 Dec;172(2):495-503 |
1 | J:233385 Castinetti F, Brinkmeier ML, Mortensen AH, Vella KR, Gergics P, Brue T, Hollenberg AN, Gan L, Camper SA, ISL1 Is Necessary for Maximal Thyrotrope Response to Hypothyroidism. Mol Endocrinol. 2015 Oct;29(10):1510-21 |
1* | J:73085 Dasen JS, Barbera JP, Herman TS, Connell SO, Olson L, Ju B, Tollkuhn J, Baek SH, Rose DW, Rosenfeld MG, Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 1;15(23):3193-207 |
1 | J:70561 Dasen JS, O'Connell SM, Flynn SE, Treier M, Gleiberman AS, Szeto DP, Hooshmand F, Aggarwal AK, Rosenfeld MG, Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types. Cell. 1999 May 28;97(5):587-98 |
1* | J:143548 Himes AD, Raetzman LT, Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1. Dev Biol. 2009 Jan 1;325(1):151-61 |
1* | J:19457 Japon MA, Rubinstein M, Low MJ, In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development. J Histochem Cytochem. 1994 Aug;42(8):1117-25 |
1 | J:89087 Lamolet B, Poulin G, Chu K, Guillemot F, Tsai MJ, Drouin J, Tpit-independent function of NeuroD1(BETA2) in pituitary corticotroph differentiation. Mol Endocrinol. 2004 Apr;18(4):995-1003 |
2* | J:228711 Lanctot C, Gauthier Y, Drouin J, Pituitary homeobox 1 (Ptx1) is differentially expressed during pituitary development. Endocrinology. 1999 Mar;140(3):1416-22 |
1 | J:332513 Laporte E, De Vriendt S, Hoekx J, Vankelecom H, Interleukin-6 is dispensable in pituitary normal development and homeostasis but needed for pituitary stem cell activation following local injury. Front Endocrinol (Lausanne). 2022;13:1092063 |
1* | J:33102 Lin C, Lin SC, Chang CP, Rosenfeld MG, Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth [see comments]. Nature. 1992 Dec 24-31;360(6406):765-8 |
1 | J:17223 Lin SC, Li S, Drolet DW, Rosenfeld MG, Pituitary ontogeny of the Snell dwarf mouse reveals Pit-1-independent and Pit-1-dependent origins of the thyrotrope. Development. 1994 Mar;120(3):515-22 |
1 | J:114149 Pope C, McNeilly JR, Coutts S, Millar M, Anderson RA, McNeilly AS, Gonadotrope and thyrotrope development in the human and mouse anterior pituitary gland. Dev Biol. 2006 Sep 1;297(1):172-81 |
1* | J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20 |
1 | J:81212 Quirk CC, Seachrist DD, Nilson JH, Embryonic Expression of the Luteinizing Hormone beta Gene Appears to Be Coupled to the Transient Appearance of p8, a High Mobility Group-related Transcription Factor. J Biol Chem. 2003 Jan 17;278(3):1680-5 |
Chac1 ChaC, cation transport regulator 1 (Synonyms: 1810008K03Rik, Botch) | |
Results | Reference |
2* | J:184017 Chi Z, Zhang J, Tokunaga A, Harraz MM, Byrne ST, Dolinko A, Xu J, Blackshaw S, Gaiano N, Dawson TM, Dawson VL, Botch promotes neurogenesis by antagonizing Notch. Dev Cell. 2012 Apr 17;22(4):707-20 |
1 | J:172737 Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RA, Peterson AS, Solloway MJ, Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol. 2011 May 30;193(5):935-51 |
Chat choline O-acetyltransferase (Synonyms: B230380D24Rik) | |
Results | Reference |
1 | J:92351 Burau K, Stenull I, Huber K, Misawa H, Berse B, Unsicker K, Ernsberger U, c-ret regulates cholinergic properties in mouse sympathetic neurons: evidence from mutant mice. Eur J Neurosci. 2004 Jul;20(2):353-62 |
1 | J:330829 Cabirol MJ, Cardoit L, Courtand G, Mayeur ME, Simmers J, Pascual O, Thoby-Brisson M, Microglia shape the embryonic development of mammalian respiratory networks. Elife. 2022 Nov 2;11:e80352 |
1 | J:163224 Garcia-Lopez M, Abellan A, Legaz I, Rubenstein JL, Puelles L, Medina L, Histogenetic compartments of the mouse centromedial and extended amygdala based on gene expression patterns during development. J Comp Neurol. 2008 Jan 1;506(1):46-74 |
1 | J:306265 Hao MM, Fung C, Boesmans W, Lowette K, Tack J, Vanden Berghe P, Development of the intrinsic innervation of the small bowel mucosa and villi. Am J Physiol Gastrointest Liver Physiol. 2020 Jan 1;318(1):G53-G65 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
1 | J:182013 Lopes R, Verhey van Wijk N, Neves G, Pachnis V, Transcription factor LIM homeobox 7 (Lhx7) maintains subtype identity of cholinergic interneurons in the mammalian striatum. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3119-24 |
1 | J:37118 McEvilly RJ, Erkman L, Luo L, Sawchenko PE, Ryan AF, Rosenfeld MG, Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature. 1996 Dec 12;384(6609):574-7 |
1 | J:286923 Nasirova N, Quina LA, Agosto-Marlin IM, Ramirez JM, Lambe EK, Turner EE, Dual recombinase fate mapping reveals a transient cholinergic phenotype in multiple populations of developing glutamatergic neurons. J Comp Neurol. 2020 Feb 1;528(2):283-307 |
1 | J:176239 Pombero A, Bueno C, Saglietti L, Rodenas M, Guimera J, Bulfone A, Martinez S, Pallial origin of basal forebrain cholinergic neurons in the nucleus basalis of Meynert and horizontal limb of the diagonal band nucleus. Development. 2011 Oct;138(19):4315-26 |
1* | J:224572 Pombero A, Martinez S, The alpha2-subunit of the nicotinic cholinergic receptor is specifically expressed in medial subpallium-derived cells of mammalian amygdala. J Comp Neurol. 2015 Aug 1;523(11):1608-21 |
1 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
Chd1l chromodomain helicase DNA binding protein 1-like (Synonyms: 4432404A22Rik, Snf2p) | |
Results | Reference |
1* | J:302850 Liu M, Chen L, Ma NF, Chow RK, Li Y, Song Y, Chan TH, Fang S, Yang X, Xi S, Jiang L, Li Y, Zeng TT, Li Y, Yuan YF, Guan XY, CHD1L promotes lineage reversion of hepatocellular carcinoma through opening chromatin for key developmental transcription factors. Hepatology. 2016 May;63(5):1544-59 |
Chd3 chromodomain helicase DNA binding protein 3 (Synonyms: 2600010P09Rik, Chd7, Mi-2 alpha, Prp7, Prp9-1) | |
Results | Reference |
1 | J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39 |
Chd4 chromodomain helicase DNA binding protein 4 (Synonyms: 9530019N15Rik, D6Ertd380e, MGC:11769, Mi-2beta) | |
Results | Reference |
1 | J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39 |
1 | J:135131 Kashiwagi M, Morgan BA, Georgopoulos K, The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny. Development. 2007 Apr;134(8):1571-82 |
2 | J:198821 Sparmann A, Xie Y, Verhoeven E, Vermeulen M, Lancini C, Gargiulo G, Hulsman D, Mann M, Knoblich JA, van Lohuizen M, The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation. EMBO J. 2013 May 29;32(11):1598-612 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
1 | J:300882 Xu H, Fame RM, Sadegh C, Sutin J, Naranjo C, Della Syau, Cui J, Shipley FB, Vernon A, Gao F, Zhang Y, Holtzman MJ, Heiman M, Warf BC, Lin PY, Lehtinen MK, Choroid plexus NKCC1 mediates cerebrospinal fluid clearance during mouse early postnatal development. Nat Commun. 2021 Jan 19;12(1):447 |
Chd7 chromodomain helicase DNA binding protein 7 (Synonyms: A730019I05Rik, Cycn, Cyn, Dz, Edy, Flo, GENA 47, Gena 52, GENA 60, Lda, Mt, Obt, Todo, WBE1, Whi) | |
Results | Reference |
2 | J:314588 Ahmed M, Moon R, Prajapati RS, James E, Albert Basson M, Streit A, The chromatin remodelling factor Chd7 protects auditory neurons and sensory hair cells from stress-induced degeneration. Commun Biol. 2021 Nov 3;4(1):1260 |
1 | J:310063 Balendran V, Skidmore JM, Ritter KE, Gao J, Cimerman J, Beyer LA, Hurd EA, Raphael Y, Martin DM, Chromatin remodeler CHD7 is critical for cochlear morphogenesis and neurosensory patterning. Dev Biol. 2021 Sep;477:11-21 |
1* | J:161880 Bergman JE, Bosman EA, van Ravenswaaij-Arts CM, Steel KP, Study of smell and reproductive organs in a mouse model for CHARGE syndrome. Eur J Hum Genet. 2010 Feb;18(2):171-7 |
1* | J:104123 Bosman EA, Penn AC, Ambrose JC, Kettleborough R, Stemple DL, Steel KP, Multiple mutations in mouse Chd7 provide models for CHARGE syndrome. Hum Mol Genet. 2005 Nov 15;14(22):3463-76 |
1 | J:242933 Whittaker DE, Riegman KL, Kasah S, Mohan C, Yu T, Sala BP, Hebaishi H, Caruso A, Marques AC, Michetti C, Smachetti ME, Shah A, Sabbioni M, Kulhanci O, Tee WW, Reinberg D, Scattoni ML, Volk H, McGonnell I, Wardle FC, Fernandes C, Basson MA, The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression. J Clin Invest. 2017 Mar 01;127(3):874-887 |
Chd8 chromodomain helicase DNA binding protein 8 (Synonyms: 5830451P18Rik, Duplin, mKIAA1564) | |
Results | Reference |
1* | J:92968 Nishiyama M, Nakayama K, Tsunematsu R, Tsukiyama T, Kikuchi A, Nakayama KI, Early embryonic death in mice lacking the beta-catenin-binding protein Duplin. Mol Cell Biol. 2004 Oct;24(19):8386-94 |
1 | J:250811 Platt RJ, Zhou Y, Slaymaker IM, Shetty AS, Weisbach NR, Kim JA, Sharma J, Desai M, Sood S, Kempton HR, Crabtree GR, Feng G, Zhang F, Chd8 Mutation Leads to Autistic-like Behaviors and Impaired Striatal Circuits. Cell Rep. 2017 Apr 11;19(2):335-350 |
Chd9 chromodomain helicase DNA binding protein 9 (Synonyms: 1810014J18Rik, 9030205D12Rik, A330063D19Rik, AD013, mKIAA0308) | |
Results | Reference |
1* | J:306243 Shur I, Socher R, Benayahu D, In vivo association of CReMM/CHD9 with promoters in osteogenic cells. J Cell Physiol. 2006 May;207(2):374-8 |
Chek1 checkpoint kinase 1 (Synonyms: Chk1) | |
Results | Reference |
1 | J:181920 Lee Y, Shull ER, Frappart PO, Katyal S, Enriquez-Rios V, Zhao J, Russell HR, Brown EJ, McKinnon PJ, ATR maintains select progenitors during nervous system development. EMBO J. 2012 Mar 7;31(5):1177-89 |
1 | J:185038 Martinez P, Flores JM, Blasco MA, 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response. J Cell Biol. 2012 Apr 16;197(2):283-300 |
Chek2 checkpoint kinase 2 (Synonyms: CHK2, Rad53) | |
Results | Reference |
1 | J:181920 Lee Y, Shull ER, Frappart PO, Katyal S, Enriquez-Rios V, Zhao J, Russell HR, Brown EJ, McKinnon PJ, ATR maintains select progenitors during nervous system development. EMBO J. 2012 Mar 7;31(5):1177-89 |
Chga chromogranin A (Synonyms: ChrA) | |
Results | Reference |
1 | J:305792 Ansarullah, Jain C, Far FF, Homberg S, Wissmiller K, von Hahn FG, Raducanu A, Schirge S, Sterr M, Bilekova S, Siehler J, Wiener J, Oppenlander L, Morshedi A, Bastidas-Ponce A, Collden G, Irmler M, Beckers J, Feuchtinger A, Grzybek M, Ahlbrecht C, Feederle R, Plettenburg O, Muller TD, Meier M, Tschop MH, Coskun U, Lickert H, Inceptor counteracts insulin signalling in beta-cells to control glycaemia. Nature. 2021 Feb;590(7845):326-331 |
1 | J:283354 Guiu J, Hannezo E, Yui S, Demharter S, Ulyanchenko S, Maimets M, Jorgensen A, Perlman S, Lundvall L, Mamsen LS, Larsen A, Olesen RH, Andersen CY, Thuesen LL, Hare KJ, Pers TH, Khodosevich K, Simons BD, Jensen KB, Tracing the origin of adult intestinal stem cells. Nature. 2019 Jun;570(7759):107-111 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
1 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
2 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
2 | J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461 |
1 | J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356 |
1 | J:338071 Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn LJ, Rosenthal B, Gurtler M, Estanboulieh RR, Shvartsman D, Gifford DK, Trapnell C, Melton D, A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets. Cell. 2019 Feb 7;176(4):790-804.e13 |
1 | J:284493 Sharon N, Vanderhooft J, Straubhaar J, Mueller J, Chawla R, Zhou Q, Engquist EN, Trapnell C, Gifford DK, Melton DA, Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development. Cell Rep. 2019 May 21;27(8):2281-2291.e5 |
Chgb chromogranin B (Synonyms: Scg-1, secretogranin I) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1* | J:281311 Nakano Y, Wiechert S, Banfi B, Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8 |
1 | J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12) |
Chil3 chitinase-like 3 (Synonyms: Chi3l3, Ym1) | |
Results | Reference |
1* | J:170267 Chaignat E, Yahya-Graison EA, Henrichsen CN, Chrast J, Schutz F, Pradervand S, Reymond A, Copy number variation modifies expression time courses. Genome Res. 2011 Jan;21(1):106-13 |
2 | J:77900 Hung SI, Chang AC, Kato I, Chang NC, Transient expression of Ym1, a heparin-binding lectin, during developmental hematopoiesis and inflammation. J Leukoc Biol. 2002 Jul;72(1):72-82 |
Chl1 cell adhesion molecule L1-like (Synonyms: A530023M13Rik, CALL, close homolog of L1, LICAM2) | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
2 | J:130566 Wright AG, Demyanenko GP, Powell A, Schachner M, Enriquez-Barreto L, Tran TS, Polleux F, Maness PF, Close homolog of L1 and neuropilin 1 mediate guidance of thalamocortical axons at the ventral telencephalon. J Neurosci. 2007 Dec 12;27(50):13667-79 |
Chmp2a charged multivesicular body protein 2A (Synonyms: 1500016L11Rik, chromatin modifying protein 2A) | |
Results | Reference |
1* | J:339600 Hermosilla Aguayo V, Martin P, Tian N, Zheng J, Aho R, Losa M, Selleri L, ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42 |
Chmp4b charged multivesicular body protein 4B (Synonyms: 2010012F05Rik, chromatin modifying protein 4B, Snf7-2) | |
Results | Reference |
1* | J:339600 Hermosilla Aguayo V, Martin P, Tian N, Zheng J, Aho R, Losa M, Selleri L, ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42 |
Chmp6 charged multivesicular body protein 6 (Synonyms: 2400004G01Rik, chromatin modifying protein 6) | |
Results | Reference |
1* | J:339600 Hermosilla Aguayo V, Martin P, Tian N, Zheng J, Aho R, Losa M, Selleri L, ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42 |
Chmp7 charged multivesicular body protein 7 (Synonyms: 4930596K11Rik, 6330407G04Rik, CHMP family, member 7) | |
Results | Reference |
1* | J:339600 Hermosilla Aguayo V, Martin P, Tian N, Zheng J, Aho R, Losa M, Selleri L, ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42 |
Chn1 chimerin 1 (Synonyms: 0610007I19Rik, 0710001E19Rik, 1700112L09Rik, 2900046J01Rik, alpha1 chimaerin, alpha2 chimaerin, ARHGAP2) | |
Results | Reference |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Chpf chondroitin polymerizing factor (Synonyms: 1700028N03Rik, D1Bwg1363e) | |
Results | Reference |
1* | J:120970 Sakai K, Kimata K, Sato T, Gotoh M, Narimatsu H, Shinomiya K, Watanabe H, Chondroitin sulfate N-acetylgalactosaminyltransferase-1 plays a critical role in chondroitin sulfate synthesis in cartilage. J Biol Chem. 2007 Feb 9;282(6):4152-61 |
Chpf2 chondroitin polymerizing factor 2 (Synonyms: 2010209O12Rik) | |
Results | Reference |
1* | J:120970 Sakai K, Kimata K, Sato T, Gotoh M, Narimatsu H, Shinomiya K, Watanabe H, Chondroitin sulfate N-acetylgalactosaminyltransferase-1 plays a critical role in chondroitin sulfate synthesis in cartilage. J Biol Chem. 2007 Feb 9;282(6):4152-61 |
Chrd chordin (Synonyms: Chd) | |
Results | Reference |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
Chrdl1 chordin-like 1 (Synonyms: CHL1, Nrln1, ventroptin-alpha, verntroptin-beta, VOPT) | |
Results | Reference |
1 | J:131661 Rizzolio F, Bione S, Sala C, Tribioli C, Ciccone R, Zuffardi O, di Iorgi N, Maghnie M, Toniolo D, Highly conserved non-coding sequences and the 18q critical region for short stature: a common mechanism of disease?. PLoS One. 2008;3(1):e1460 |
Chrm1 cholinergic receptor, muscarinic 1, CNS (Synonyms: AW495047, Chrm-1, M1, M1R, muscarinic acetylcholine receptor 1) | |
Results | Reference |
1 | J:26554 Lammerding-Koppel M, Greiner-Schroder A, Drews U, Muscarinic receptors in the prenatal mouse embryo. Comparison of M35-immunohistochemistry with [3H]quinuclidinyl benzylate autoradiography. Histochem Cell Biol. 1995 Apr;103(4):301-10 |
Chrm2 cholinergic receptor, muscarinic 2, cardiac (Synonyms: AChR M2, Chrm-2, M2, muscarinic acetylcholine receptor 2) | |
Results | Reference |
1 | J:26554 Lammerding-Koppel M, Greiner-Schroder A, Drews U, Muscarinic receptors in the prenatal mouse embryo. Comparison of M35-immunohistochemistry with [3H]quinuclidinyl benzylate autoradiography. Histochem Cell Biol. 1995 Apr;103(4):301-10 |
Chrm3 cholinergic receptor, muscarinic 3, cardiac (Synonyms: Chrm-3, M3R, muscarinic acetylcholine receptor 3) | |
Results | Reference |
1 | J:26554 Lammerding-Koppel M, Greiner-Schroder A, Drews U, Muscarinic receptors in the prenatal mouse embryo. Comparison of M35-immunohistochemistry with [3H]quinuclidinyl benzylate autoradiography. Histochem Cell Biol. 1995 Apr;103(4):301-10 |
Chrm4 cholinergic receptor, muscarinic 4 (Synonyms: Chrm-4, muscarinic acetylcholine receptor 4) | |
Results | Reference |
1 | J:26554 Lammerding-Koppel M, Greiner-Schroder A, Drews U, Muscarinic receptors in the prenatal mouse embryo. Comparison of M35-immunohistochemistry with [3H]quinuclidinyl benzylate autoradiography. Histochem Cell Biol. 1995 Apr;103(4):301-10 |
1 | J:238868 Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z, The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 2016 Aug 02;16(5):1431-44 |
Chrm5 cholinergic receptor, muscarinic 5 (Synonyms: M5R, muscarinic acetylcholine receptor 5) | |
Results | Reference |
1 | J:26554 Lammerding-Koppel M, Greiner-Schroder A, Drews U, Muscarinic receptors in the prenatal mouse embryo. Comparison of M35-immunohistochemistry with [3H]quinuclidinyl benzylate autoradiography. Histochem Cell Biol. 1995 Apr;103(4):301-10 |
Chrna1 cholinergic receptor nicotinic alpha 1 subunit (Synonyms: Achr-1, Acra) | |
Results | Reference |
1 | J:126807 Hippenmeyer S, Huber RM, Ladle DR, Murphy K, Arber S, ETS transcription factor Erm controls subsynaptic gene expression in skeletal muscles. Neuron. 2007 Sep 6;55(5):726-40 |
1 | J:134988 Liu Y, Padgett D, Takahashi M, Li H, Sayeed A, Teichert RW, Olivera BM, McArdle JJ, Green WN, Lin W, Essential roles of the acetylcholine receptor {gamma}-subunit in neuromuscular synaptic patterning. Development. 2008 Jun;135(11):1957-67 |
Chrna2 cholinergic receptor nicotinic alpha 2 subunit (Synonyms: Acra-2, Acra2, MGC:18795) | |
Results | Reference |
1* | J:224572 Pombero A, Martinez S, The alpha2-subunit of the nicotinic cholinergic receptor is specifically expressed in medial subpallium-derived cells of mammalian amygdala. J Comp Neurol. 2015 Aug 1;523(11):1608-21 |
Chrna3 cholinergic receptor, nicotinic, alpha polypeptide 3 (Synonyms: (a)3, A730007P14Rik, Acra-3, Acra3, alpha 3, neuronal nicotinic acetylcholine receptor, alpha 3 subunit) | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Chrna7 cholinergic receptor, nicotinic, alpha polypeptide 7 (Synonyms: Acra7, alpha7, alpha7-nAChR, alpha7 nicotinic receptor) | |
Results | Reference |
1 | J:223161 Gahring LC, Myers E, Palumbos S, Rogers SW, Nicotinic receptor Alpha7 expression during mouse adrenal gland development. PLoS One. 2014;9(8):e103861 |
1 | J:101308 Reynolds PR, Hoidal JR, Temporal-spatial expression and transcriptional regulation of alpha7 nicotinic acetylcholine receptor by thyroid transcription factor-1 and early growth response factor-1 during murine lung development. J Biol Chem. 2005 Sep 16;280(37):32548-54 |
1* | J:222345 Rogers SW, Gahring LC, Nicotinic receptor Alpha7 expression during tooth morphogenesis reveals functional pleiotropy. PLoS One. 2012;7(5):e36467 |
Chrnb1 cholinergic receptor nicotinic beta 1 subunit (Synonyms: Achr-2, AChR beta, Acrb) | |
Results | Reference |
1 | J:37005 Noakes PG, Phillips WD, Hanley TA, Sanes JR, Merlie JP, 43K protein and acetylcholine receptors colocalize during the initial stages of neuromuscular synapse formation in vivo. Dev Biol. 1991;155(1):275-80 |
Chrnb4 cholinergic receptor, nicotinic, beta polypeptide 4 (Synonyms: Acrb-4, Acrb4) | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Chrnd cholinergic receptor, nicotinic, delta polypeptide (Synonyms: Achr-4, Acrd) | |
Results | Reference |
1 | J:37005 Noakes PG, Phillips WD, Hanley TA, Sanes JR, Merlie JP, 43K protein and acetylcholine receptors colocalize during the initial stages of neuromuscular synapse formation in vivo. Dev Biol. 1991;155(1):275-80 |
Chrne cholinergic receptor, nicotinic, epsilon polypeptide (Synonyms: AChrepsilon, Acre) | |
Results | Reference |
1 | J:134988 Liu Y, Padgett D, Takahashi M, Li H, Sayeed A, Teichert RW, Olivera BM, McArdle JJ, Green WN, Lin W, Essential roles of the acetylcholine receptor {gamma}-subunit in neuromuscular synaptic patterning. Development. 2008 Jun;135(11):1957-67 |
Chrng cholinergic receptor, nicotinic, gamma polypeptide (Synonyms: Achr-3, Acrg) | |
Results | Reference |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1 | J:37005 Noakes PG, Phillips WD, Hanley TA, Sanes JR, Merlie JP, 43K protein and acetylcholine receptors colocalize during the initial stages of neuromuscular synapse formation in vivo. Dev Biol. 1991;155(1):275-80 |
Chsy1 chondroitin sulfate synthase 1 (Synonyms: mKIAA0990, skt) | |
Results | Reference |
1* | J:120970 Sakai K, Kimata K, Sato T, Gotoh M, Narimatsu H, Shinomiya K, Watanabe H, Chondroitin sulfate N-acetylgalactosaminyltransferase-1 plays a critical role in chondroitin sulfate synthesis in cartilage. J Biol Chem. 2007 Feb 9;282(6):4152-61 |
Chsy3 chondroitin sulfate synthase 3 (Synonyms: 4833446K15Rik) | |
Results | Reference |
1* | J:120970 Sakai K, Kimata K, Sato T, Gotoh M, Narimatsu H, Shinomiya K, Watanabe H, Chondroitin sulfate N-acetylgalactosaminyltransferase-1 plays a critical role in chondroitin sulfate synthesis in cartilage. J Biol Chem. 2007 Feb 9;282(6):4152-61 |
Chtop chromatin target of PRMT1 (Synonyms: 2500003M10Rik, Fop, friend of Prmt1) | |
Results | Reference |
1* | J:156247 van Dijk TB, Gillemans N, Stein C, Fanis P, Demmers J, van de Corput M, Essers J, Grosveld F, Bauer UM, Philipsen S, Friend of Prmt1, a novel chromatin target of protein arginine methyltransferases. Mol Cell Biol. 2010 Jan;30(1):260-72 |
Chuk conserved helix-loop-helix ubiquitous kinase (Synonyms: Chuk1, IkappaB kinase alpha, IKK 1, IKK-1, IKK1, IKK[a], IKK alpha, IKK-alpha, IKKalpha) | |
Results | Reference |
1 | J:234343 Kawasaki M, Kawasaki K, Oommen S, Blackburn J, Watanabe M, Nagai T, Kitamura A, Maeda T, Liu B, Schmidt-Ullrich R, Akiyama T, Inoue J, Hammond NL, Sharpe PT, Ohazama A, Regional regulation of Filiform tongue papillae development by Ikkalpha/Irf6. Dev Dyn. 2016 Sep;245(9):937-46 |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
Cic capicua transcriptional repressor (Synonyms: 1200010B10Rik, mKIAA0306) | |
Results | Reference |
1 | J:240674 Lu HC, Tan Q, Rousseaux MW, Wang W, Kim JY, Richman R, Wan YW, Yeh SY, Patel JM, Liu X, Lin T, Lee Y, Fryer JD, Han J, Chahrour M, Finnell RH, Lei Y, Zurita-Jimenez ME, Ahimaz P, Anyane-Yeboa K, Van Maldergem L, Lehalle D, Jean-Marcais N, Mosca-Boidron AL, Thevenon J, Cousin MA, Bro DE, Lanpher BC, Klee EW, Alexander N, Bainbridge MN, Orr HT, Sillitoe RV, Ljungberg MC, Liu Z, Schaaf CP, Zoghbi HY, Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nat Genet. 2017 Apr;49(4):527-536 |
Cidea cell death-inducing DNA fragmentation factor, alpha subunit-like effector A | |
Results | Reference |
1 | J:324530 Fonseca TL, Russo SC, Luongo C, Salvatore D, Bianco AC, Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 May 1;163(5) |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
Cilk1 ciliogenesis associated kinase 1 (Synonyms: 2210420N10Rik, Ick) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Cilp cartilage intermediate layer protein, nucleotide pyrophosphohydrolase (Synonyms: C130036G17Rik) | |
Results | Reference |
1* | J:177564 Bernardo BC, Belluoccio D, Rowley L, Little CB, Hansen U, Bateman JF, Cartilage Intermediate Layer Protein 2 (CILP-2) Is Expressed in Articular and Meniscal Cartilage and Down-regulated in Experimental Osteoarthritis. J Biol Chem. 2011 Oct 28;286(43):37758-67 |
Cilp2 cartilage intermediate layer protein 2 (Synonyms: 1110031K21Rik, CLIP-2) | |
Results | Reference |
1* | J:177564 Bernardo BC, Belluoccio D, Rowley L, Little CB, Hansen U, Bateman JF, Cartilage Intermediate Layer Protein 2 (CILP-2) Is Expressed in Articular and Meniscal Cartilage and Down-regulated in Experimental Osteoarthritis. J Biol Chem. 2011 Oct 28;286(43):37758-67 |
Cish cytokine inducible SH2-containing protein (Synonyms: Cis, CIS1, cytokine-inducible SH2 protein, F23) | |
Results | Reference |
1* | J:257927 Fairchild CL, Hino K, Han JS, Miltner AM, Peinado Allina G, Brown CE, Burns ME, La Torre A, Simo S, RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3):dev155283 |
1 | J:62883 Polizzotto MN, Bartlett PF, Turnley AM, Expression of 'suppressor of cytokine signalling' (SOCS) genes in the developing and adult mouse nervous system. J Comp Neurol. 2000 Jul 24;423(2):348-58 |
Cit citron (Synonyms: C030025P15Rik, Cit-k, citron kinase, citron-N, CRIK, CRIK-SK) | |
Results | Reference |
1 | J:102817 Di Cunto F, Ferrara L, Curtetti R, Imarisio S, Guazzone S, Broccoli V, Bulfone A, Altruda F, Vercelli A, Silengo L, Role of citron kinase in dendritic morphogenesis of cortical neurons. Brain Res Bull. 2003 May 30;60(4):319-27 |
3 | J:77297 Di Cunto F, Imarisio S, Hirsch E, Broccoli V, Bulfone A, Migheli A, Atzori C, Turco E, Triolo R, Dotto GP, Silengo L, Altruda F, Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis. Neuron. 2000 Oct;28(1):115-27 |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 (Synonyms: Msg1) | |
Results | Reference |
1 | J:315767 Ahn SY, Kim Y, Kim ST, Swat W, Miner JH, Scaffolding proteins DLG1 and CASK cooperate to maintain the nephron progenitor population during kidney development. J Am Soc Nephrol. 2013 Jun;24(7):1127-38 |
1 | J:321428 Kruber P, Angay O, Winkler A, Bosl MR, Kneitz S, Heinze KG, Gessler M, Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation. Int J Cancer. 2019 Mar 15;144(6):1391-1400 |
2* | J:193906 Murphy AJ, de Caestecker C, Pierce J, Boyle SC, Ayers GD, Zhao Z, Libes JM, Correa H, Walter T, Huppert SS, Perantoni AO, de Caestecker MP, Lovvorn HN 3rd, CITED1 expression in liver development and hepatoblastoma. Neoplasia. 2012 Dec;14(12):1153-63 |
Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (Synonyms: Mrg1, Msg2, p35srj) | |
Results | Reference |
1 | J:140378 Qu X, Lam E, Doughman YQ, Chen Y, Chou YT, Lam M, Turakhia M, Dunwoodie SL, Watanabe M, Xu B, Duncan SA, Yang YC, Cited2, a coactivator of HNF4alpha, is essential for liver development. EMBO J. 2007 Oct 31;26(21):4445-56 |
1* | J:136063 Xu B, Qu X, Gu S, Doughman YQ, Watanabe M, Dunwoodie SL, Yang YC, Cited2 is required for fetal lung maturation. Dev Biol. 2008 May 1;317(1):95-105 |
Ckb creatine kinase, brain (Synonyms: B-CK, Ck-3) | |
Results | Reference |
1* | J:56670 Washabaugh CH, Ontell MP, Kant JA, Ontell M, Creatine kinase transcript accumulation: effect of nerve during muscle development. Dev Dyn. 1999 Aug;215(4):285-96 |
Ckm creatine kinase, muscle (Synonyms: Ckmm, M-CK, MCK) | |
Results | Reference |
1 | J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1* | J:52277 Lu J, Webb R, Richardson JA, Olson EN, MyoR: a muscle-restricted basic helix-loop-helix transcription factor that antagonizes the actions of MyoD. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):552-7 |
1 | J:160383 Messina G, Biressi S, Monteverde S, Magli A, Cassano M, Perani L, Roncaglia E, Tagliafico E, Starnes L, Campbell CE, Grossi M, Goldhamer DJ, Gronostajski RM, Cossu G, Nfix regulates fetal-specific transcription in developing skeletal muscle. Cell. 2010 Feb 19;140(4):554-66 |
1 | J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97 |
1 | J:361958 Straube P, Beckers A, Jany UWH, Bergmann F, Ludtke TH, Rudat C, Trowe MO, Peters I, Klopf MG, Mamo TM, Kispert A, Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter. Development. 2025 Feb 1;152(3) |
1* | J:56670 Washabaugh CH, Ontell MP, Kant JA, Ontell M, Creatine kinase transcript accumulation: effect of nerve during muscle development. Dev Dyn. 1999 Aug;215(4):285-96 |
Ckmt2 creatine kinase, mitochondrial 2 (Synonyms: 2300008A19Rik, ScCKmit) | |
Results | Reference |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Cks1b CDC28 protein kinase 1b (Synonyms: 2410005G18Rik, 2610005D03Rik, Cks1) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
Cks2 CDC28 protein kinase regulatory subunit 2 (Synonyms: 1110038L14Rik, CKSHS2) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
Clasp2 CLIP associating protein 2 (Synonyms: 1500004F14Rik, 8030404L10Rik, CLASP2, CLASP2alpha, CLASP2beta, CLASP2gamma, mKIAA0627) | |
Results | Reference |
2 | J:269775 Dillon GM, Tyler WA, Omuro KC, Kambouris J, Tyminski C, Henry S, Haydar TF, Beffert U, Ho A, CLASP2 Links Reelin to the Cytoskeleton during Neocortical Development. Neuron. 2017 Mar 22;93(6):1344-1358.e5 |
Clca3a1 chloride channel accessory 3A1 (Synonyms: Clca1) | |
Results | Reference |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Clca3a2 chloride channel accessory 3A2 (Synonyms: Clca2) | |
Results | Reference |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Clcf1 cardiotrophin-like cytokine factor 1 (Synonyms: Bsf3, CLC, NNT-1/BSF-3) | |
Results | Reference |
2* | J:99504 de Bovis B, Derouet D, Gauchat JF, Elson G, Gascan H, Delapeyriere O, clc is co-expressed with clf or cntfr in developing mouse muscles. Cell Commun Signal. 2005 Jan 31;3(1):1 |
Clcn5 chloride channel, voltage-sensitive 5 (Synonyms: 5430408K11Rik, Clc4-1, Clc5, ClC-5, Clcn4-1, D930009B12Rik, DXImx42e, Sfc13) | |
Results | Reference |
2 | J:154841 Jouret F, Igarashi T, Gofflot F, Wilson PD, Karet FE, Thakker RV, Devuyst O, Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5. Kidney Int. 2004 Jan;65(1):198-208 |
Clcn7 chloride channel, voltage-sensitive 7 (Synonyms: ClC-7) | |
Results | Reference |
2 | J:67273 Kornak U, Kasper D, Bosl MR, Kaiser E, Schweizer M, Schulz A, Friedrich W, Delling G, Jentsch TJ, Loss of the ClC-7 chloride channel leads to osteopetrosis in mice and man. Cell. 2001 Jan 26;104(2):205-15 |
Clcnkb chloride channel, voltage-sensitive Kb (Synonyms: Clck2, ClC-K2, Clcnk1l, Clcnk2) | |
Results | Reference |
1 | J:249431 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ, Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6:e26851 |
Cldn1 claudin 1 | |
Results | Reference |
3* | J:93085 Hashizume A, Ueno T, Furuse M, Tsukita S, Nakanishi Y, Hieda Y, Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn. 2004 Oct;231(2):425-31 |
1 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1* | J:107229 Ohta H, Adachi H, Inaba M, Developmental changes in the expression of tight junction protein claudins in murine metanephroi and embryonic kidneys. J Vet Med Sci. 2006 Feb;68(2):149-55 |
1* | J:117802 Troy TC, Li Y, O'malley L, Turksen K, The temporal and spatial expression of Claudins in epidermal development and the accelerated program of epidermal differentiation in K14-CaSR transgenic mice. Gene Expr Patterns. 2007 Feb;7(4):423-30 |
1 | J:302296 Vong KI, Ma TC, Li B, Leung TCN, Nong W, Ngai SM, Hui JHL, Jiang L, Kwan KM, SOX9-COL9A3-dependent regulation of choroid plexus epithelial polarity governs blood-cerebrospinal fluid barrier integrity. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2009568118 |
1 | J:199582 Youssef G, Gerner L, Naeem AS, Ralph O, Ono M, O'Neill CA, O'Shaughnessy RF, Rab3Gap1 mediates exocytosis of Claudin-1 and tight junction formation during epidermal barrier acquisition. Dev Biol. 2013 Aug 15;380(2):274-85 |
Cldn2 claudin 2 | |
Results | Reference |
3* | J:93085 Hashizume A, Ueno T, Furuse M, Tsukita S, Nakanishi Y, Hieda Y, Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn. 2004 Oct;231(2):425-31 |
1* | J:107229 Ohta H, Adachi H, Inaba M, Developmental changes in the expression of tight junction protein claudins in murine metanephroi and embryonic kidneys. J Vet Med Sci. 2006 Feb;68(2):149-55 |
1* | J:117802 Troy TC, Li Y, O'malley L, Turksen K, The temporal and spatial expression of Claudins in epidermal development and the accelerated program of epidermal differentiation in K14-CaSR transgenic mice. Gene Expr Patterns. 2007 Feb;7(4):423-30 |
Cldn3 claudin 3 (Synonyms: Cpetr2) | |
Results | Reference |
2 | J:253618 Bonney S, Siegenthaler JA, Differential Effects of Retinoic Acid Concentrations in Regulating Blood-Brain Barrier Properties. eNeuro. 2017 May-Jun;4(3):ENEURO.0378-16.2017 |
3* | J:93085 Hashizume A, Ueno T, Furuse M, Tsukita S, Nakanishi Y, Hieda Y, Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn. 2004 Oct;231(2):425-31 |
1 | J:290414 Li J, Gordon J, Chen ELY, Xiao S, Wu L, Zuniga-Pflucker JC, Manley NR, NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development. Development. 2020 Jun 22;147(12):dev178988 |
1 | J:293206 Munoz JJ, Tobajas E, Juara S, Montero S, Zapata AG, FoxN1 mediates thymic cortex-medulla differentiation through modifying a developmental pattern based on epithelial tubulogenesis. Histochem Cell Biol. 2019 Dec;152(6):397-413 |
1* | J:107229 Ohta H, Adachi H, Inaba M, Developmental changes in the expression of tight junction protein claudins in murine metanephroi and embryonic kidneys. J Vet Med Sci. 2006 Feb;68(2):149-55 |
1* | J:117802 Troy TC, Li Y, O'malley L, Turksen K, The temporal and spatial expression of Claudins in epidermal development and the accelerated program of epidermal differentiation in K14-CaSR transgenic mice. Gene Expr Patterns. 2007 Feb;7(4):423-30 |
Cldn4 claudin 4 (Synonyms: Cpetr, Cpetr1) | |
Results | Reference |
3* | J:93085 Hashizume A, Ueno T, Furuse M, Tsukita S, Nakanishi Y, Hieda Y, Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn. 2004 Oct;231(2):425-31 |
2* | J:266596 Kersbergen A, Best SA, Dworkin S, Ah-Cann C, de Vries ME, Asselin-Labat ML, Ritchie ME, Jane SM, Sutherland KD, Lung morphogenesis is orchestrated through Grainyhead-like 2 (Grhl2) transcriptional programs. Dev Biol. 2018 Nov 1;443(1):1-9 |
1 | J:290414 Li J, Gordon J, Chen ELY, Xiao S, Wu L, Zuniga-Pflucker JC, Manley NR, NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development. Development. 2020 Jun 22;147(12):dev178988 |
1 | J:293206 Munoz JJ, Tobajas E, Juara S, Montero S, Zapata AG, FoxN1 mediates thymic cortex-medulla differentiation through modifying a developmental pattern based on epithelial tubulogenesis. Histochem Cell Biol. 2019 Dec;152(6):397-413 |
1* | J:107229 Ohta H, Adachi H, Inaba M, Developmental changes in the expression of tight junction protein claudins in murine metanephroi and embryonic kidneys. J Vet Med Sci. 2006 Feb;68(2):149-55 |
Cldn5 claudin 5 (Synonyms: Tmvcf) | |
Results | Reference |
2 | J:253618 Bonney S, Siegenthaler JA, Differential Effects of Retinoic Acid Concentrations in Regulating Blood-Brain Barrier Properties. eNeuro. 2017 May-Jun;4(3):ENEURO.0378-16.2017 |
1 | J:308918 Geng X, Yanagida K, Akwii RG, Choi D, Chen L, Ho Y, Cha B, Mahamud MR, Berman de Ruiz K, Ichise H, Chen H, Wythe JD, Mikelis CM, Hla T, Srinivasan RS, S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling. JCI Insight. 2020 Jul 23;5(14) |
3* | J:93085 Hashizume A, Ueno T, Furuse M, Tsukita S, Nakanishi Y, Hieda Y, Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn. 2004 Oct;231(2):425-31 |
1 | J:257839 Li S, Kumar T P, Joshee S, Kirschstein T, Subburaju S, Khalili JS, Kloepper J, Du C, Elkhal A, Szabo G, Jain RK, Kohling R, Vasudevan A, Endothelial cell-derived GABA signaling modulates neuronal migration and postnatal behavior. Cell Res. 2018 Feb;28(2):221-248 |
1 | J:284120 Mahamud MR, Geng X, Ho YC, Cha B, Kim Y, Ma J, Chen L, Myers G, Camper S, Mustacich D, Witte M, Choi D, Hong YK, Chen H, Varshney G, Engel JD, Wang S, Kim TH, Lim KC, Srinivasan RS, GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126. Development. 2019 Nov 5;146(21):dev184218 |
1* | J:167709 Todorovic V, Finnegan E, Freyer L, Zilberberg L, Ota M, Rifkin DB, Long form of latent TGF-beta binding protein 1 (Ltbp1L) regulates cardiac valve development. Dev Dyn. 2011 Jan;240(1):176-87 |
1* | J:117802 Troy TC, Li Y, O'malley L, Turksen K, The temporal and spatial expression of Claudins in epidermal development and the accelerated program of epidermal differentiation in K14-CaSR transgenic mice. Gene Expr Patterns. 2007 Feb;7(4):423-30 |
Cldn6 claudin 6 | |
Results | Reference |
3* | J:93085 Hashizume A, Ueno T, Furuse M, Tsukita S, Nakanishi Y, Hieda Y, Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn. 2004 Oct;231(2):425-31 |
2* | J:316194 Jimenez FR, Lewis JB, Belgique ST, Wood TT, Reynolds PR, Developmental lung expression and transcriptional regulation of claudin-6 by TTF-1, Gata-6, and FoxA2. Respir Res. 2014 Jun 26;15:70 |
1* | J:117802 Troy TC, Li Y, O'malley L, Turksen K, The temporal and spatial expression of Claudins in epidermal development and the accelerated program of epidermal differentiation in K14-CaSR transgenic mice. Gene Expr Patterns. 2007 Feb;7(4):423-30 |
Cldn7 claudin 7 | |
Results | Reference |
3* | J:93085 Hashizume A, Ueno T, Furuse M, Tsukita S, Nakanishi Y, Hieda Y, Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn. 2004 Oct;231(2):425-31 |
Cldn8 claudin 8 | |
Results | Reference |
3* | J:93085 Hashizume A, Ueno T, Furuse M, Tsukita S, Nakanishi Y, Hieda Y, Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn. 2004 Oct;231(2):425-31 |
1* | J:107229 Ohta H, Adachi H, Inaba M, Developmental changes in the expression of tight junction protein claudins in murine metanephroi and embryonic kidneys. J Vet Med Sci. 2006 Feb;68(2):149-55 |
Cldn9 claudin 9 (Synonyms: nmf329) | |
Results | Reference |
1* | J:93085 Hashizume A, Ueno T, Furuse M, Tsukita S, Nakanishi Y, Hieda Y, Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn. 2004 Oct;231(2):425-31 |
1* | J:116647 Ohazama A, Sharpe PT, Expression of claudins in murine tooth development. Dev Dyn. 2007 Jan;236(1):290-4 |
Cldn10 claudin 10 (Synonyms: 6720456I16Rik, Cldn10a, Cldn10b, D14Ertd728e) | |
Results | Reference |
2 | J:341713 Aure MH, Symonds JM, Villapudua CU, Dodge JT, Werner S, Knosp WM, Hoffman MP, FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation. Nat Commun. 2023 Oct 14;14(1):6485 |
3* | J:93085 Hashizume A, Ueno T, Furuse M, Tsukita S, Nakanishi Y, Hieda Y, Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn. 2004 Oct;231(2):425-31 |
1 | J:326201 Hayashi T, Eto K, Kadoya Y, Downregulation of ten-eleven translocation-2 triggers epithelial differentiation during organogenesis. Differentiation. 2022 May-Jun;125:45-53 |
1* | J:116647 Ohazama A, Sharpe PT, Expression of claudins in murine tooth development. Dev Dyn. 2007 Jan;236(1):290-4 |
1* | J:107229 Ohta H, Adachi H, Inaba M, Developmental changes in the expression of tight junction protein claudins in murine metanephroi and embryonic kidneys. J Vet Med Sci. 2006 Feb;68(2):149-55 |
1 | J:335569 Winningham AH, Camper SA, Pituitary Stem Cell Regulation by Zeb2 and BMP Signaling. Endocrinology. 2023 Jan 9;164(3) |
Cldn11 claudin 11 (Synonyms: oligodendrocyte-specific protein, Osp, Otm) | |
Results | Reference |
3* | J:93085 Hashizume A, Ueno T, Furuse M, Tsukita S, Nakanishi Y, Hieda Y, Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn. 2004 Oct;231(2):425-31 |
1* | J:116647 Ohazama A, Sharpe PT, Expression of claudins in murine tooth development. Dev Dyn. 2007 Jan;236(1):290-4 |
1* | J:107229 Ohta H, Adachi H, Inaba M, Developmental changes in the expression of tight junction protein claudins in murine metanephroi and embryonic kidneys. J Vet Med Sci. 2006 Feb;68(2):149-55 |
1* | J:117802 Troy TC, Li Y, O'malley L, Turksen K, The temporal and spatial expression of Claudins in epidermal development and the accelerated program of epidermal differentiation in K14-CaSR transgenic mice. Gene Expr Patterns. 2007 Feb;7(4):423-30 |
Cldn12 claudin 12 | |
Results | Reference |
1* | J:93085 Hashizume A, Ueno T, Furuse M, Tsukita S, Nakanishi Y, Hieda Y, Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn. 2004 Oct;231(2):425-31 |
Cldn16 claudin 16 (Synonyms: claudin-16, paracellin-1, PCLN1) | |
Results | Reference |
2* | J:107229 Ohta H, Adachi H, Inaba M, Developmental changes in the expression of tight junction protein claudins in murine metanephroi and embryonic kidneys. J Vet Med Sci. 2006 Feb;68(2):149-55 |
Cldn18 claudin 18 | |
Results | Reference |
1 | J:252735 Jiang M, Li H, Zhang Y, Yang Y, Lu R, Liu K, Lin S, Lan X, Wang H, Wu H, Zhu J, Zhou Z, Xu J, Lee DK, Zhang L, Lee YC, Yuan J, Abrams JA, Wang TC, Sepulveda AR, Wu Q, Chen H, Sun X, She J, Chen X, Que J, Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus. Nature. 2017 Oct 26;550(7677):529-533 |
1* | J:72106 Niimi T, Nagashima K, Ward JM, Minoo P, Zimonjic DB, Popescu NC, Kimura S, claudin-18, a Novel Downstream Target Gene for the T/EBP/NKX2.1 Homeodomain Transcription Factor, Encodes Lung- and Stomach-Specific Isoforms through Alternative Splicing. Mol Cell Biol. 2001 Nov;21(21):7380-90 |
1* | J:117802 Troy TC, Li Y, O'malley L, Turksen K, The temporal and spatial expression of Claudins in epidermal development and the accelerated program of epidermal differentiation in K14-CaSR transgenic mice. Gene Expr Patterns. 2007 Feb;7(4):423-30 |
Clec3b C-type lectin domain family 3, member b (Synonyms: Tna) | |
Results | Reference |
1 | J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132 |
3* | J:49427 Wewer UM, Iba K, Durkin ME, Nielsen FC, Loechel F, Gilpin BJ, Kuang W, Engvall E, Albrechtsen R, Tetranectin is a novel marker for myogenesis during embryonic development, muscle regeneration, and muscle cell differentiation in vitro. Dev Biol. 1998 Aug 15;200(2):247-59 |
Clec4f C-type lectin domain family 4, member f (Synonyms: Clecsf13, D18063, kupffer cell receptor) | |
Results | Reference |
2* | J:203199 Yang CY, Chen JB, Tsai TF, Tsai YC, Tsai CY, Liang PH, Hsu TL, Wu CY, Netea MG, Wong CH, Hsieh SL, CLEC4F is an inducible C-type lectin in F4/80-positive cells and is involved in alpha-galactosylceramide presentation in liver. PLoS One. 2013;8(6):e65070 |
Clec7a C-type lectin domain family 7, member a (Synonyms: beta-glucan receptor, beta-GR, BGR, Clecsf12, dectin-1) | |
Results | Reference |
1 | J:226941 Akerberg BN, Sarangam ML, Stankunas K, Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Dev Biol. 2015 Nov 1;407(1):158-72 |
Clec11a C-type lectin domain family 11, member a (Synonyms: Clecsf3, Scgf) | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Clec18a C-type lectin domain family 18, member A (Synonyms: Mrcl) | |
Results | Reference |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
Clic4 chloride intracellular channel 4 (Synonyms: D0Jmb3, mc3s5, mtCLIC) | |
Results | Reference |
1* | J:213573 Padmakumar V, Masiuk KE, Luger D, Lee C, Coppola V, Tessarollo L, Hoover SB, Karavanova I, Buonanno A, Simpson RM, Yuspa SH, Detection of differential fetal and adult expression of chloride intracellular channel 4 (CLIC4) protein by analysis of a green fluorescent protein knock-in mouse line. BMC Dev Biol. 2014;14:24 |
Clic5 chloride intracellular channel 5 (Synonyms: 5730531E12Rik, nmf318) | |
Results | Reference |
1* | J:112741 Gagnon LH, Longo-Guess CM, Berryman M, Shin JB, Saylor KW, Yu H, Gillespie PG, Johnson KR, The chloride intracellular channel protein CLIC5 is expressed at high levels in hair cell stereocilia and is essential for normal inner ear function. J Neurosci. 2006 Oct 4;26(40):10188-98 |
Clic6 chloride intracellular channel 6 (Synonyms: 5730466J16Rik, CLIC1L) | |
Results | Reference |
1* | J:160194 Shaw L, Johnson PA, Kimber SJ, Gene expression profiling of the developing mouse kidney and embryo. In Vitro Cell Dev Biol Anim. 2010 Feb;46(2):155-65 |
Clip2 CAP-GLY domain containing linker protein 2 (Synonyms: CLIP-115, Cyln2, WSCR4) | |
Results | Reference |
1* | J:45192 De Zeeuw CI, Hoogenraad CC, Goedknegt E, Hertzberg E, Neubauer A, Grosveld F, Galjart N, CLIP-115, a novel brain-specific cytoplasmic linker protein, mediates the localization of dendritic lamellar bodies. Neuron. 1997 Dec;19(6):1187-99 |
Clmn calmin (Synonyms: 9330188N17Rik) | |
Results | Reference |
2* | J:69942 Ishisaki Z, Takaishi M, Furuta I, Huh Nh, Calmin, a protein with calponin homology and transmembrane domains expressed in maturing spermatogenic cells. Genomics. 2001 Jun 1;74(2):172-9 |
Clock clock circadian regulator (Synonyms: 5330400M04Rik, bHLHe8, KAT13D, mKIAA0334) | |
Results | Reference |
2* | J:325107 Cao X, Yan Y, Luo X, Yang X, Cui H, Yang Y, Li H, Analyses of the circadian clock genes expression in whole embryos and maternal major tissues of mice. J Mol Histol. 2022 Apr;53(2):473-482 |
1* | J:158725 Dolatshad H, Cary AJ, Davis FC, Differential expression of the circadian clock in maternal and embryonic tissues of mice. PLoS One. 2010;5(3):e9855 |
1* | J:161413 Ratajczak CK, Herzog ED, Muglia LJ, Clock gene expression in gravid uterus and extra-embryonic tissues during late gestation in the mouse. Reprod Fertil Dev. 2010;22(5):743-50 |
2 | J:329949 Yuan H, Xie B, Yu X, Lin C, Li M, Zhang Y, Zou X, Lu M, Zhao M, Wen X, A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development. Front Physiol. 2022;13:981311 |
Clpp caseinolytic mitochondrial matrix peptidase proteolytic subunit (Synonyms: D17Wsu160e) | |
Results | Reference |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
Clrn1 clarin 1 (Synonyms: A130002D11Rik, clarin-1, USH3, Ush3a) | |
Results | Reference |
1 | J:150215 Geng R, Geller SF, Hayashi T, Ray CA, Reh TA, Bermingham-McDonogh O, Jones SM, Wright CG, Melki S, Imanishi Y, Palczewski K, Alagramam KN, Flannery JG, Usher syndrome IIIA gene clarin-1 is essential for hair cell function and associated neural activation. Hum Mol Genet. 2009 Aug 1;18(15):2748-60 |
Clstn1 calsyntenin 1 (Synonyms: 1810034E21Rik, alcadein alpha, calsyntenin-1, Cst-1) | |
Results | Reference |
1* | J:167050 Khan QE, Press CM, Sehic A, Landin MA, Risnes S, Osmundsen H, Expression of prion gene and presence of prion protein during development of mouse molar tooth germ. Eur J Oral Sci. 2010 Dec;118(6):559-65 |
Clstn2 calsyntenin 2 (Synonyms: 2900042C18Rik, CS2, Cst-2, CSTN2) | |
Results | Reference |
1 | J:152858 Garcia-Ortiz JE, Pelosi E, Omari S, Nedorezov T, Piao Y, Karmazin J, Uda M, Cao A, Cole SW, Forabosco A, Schlessinger D, Ottolenghi C, Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Dev Biol. 2009;9:36 |
Cltb clathrin light chain B (Synonyms: 2310046E19Rik) | |
Results | Reference |
1 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
Cltc clathrin heavy chain (Synonyms: CHC) | |
Results | Reference |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1 | J:216175 Cerqueira DM, Tran U, Romaker D, Abreu JG, Wessely O, Sterol carrier protein 2 regulates proximal tubule size in the Xenopus pronephric kidney by modulating lipid rafts. Dev Biol. 2014 Oct 1;394(1):54-64 |
Clu clusterin (Synonyms: ApoJ, Apolipoprotein J, Cli, complement lysis inhibitor, D14Ucla3, Sgp-2, Sgp2, SP-40, Sugp-2, testosterone repressed prostate message-2) | |
Results | Reference |
1* | J:14159 French LE, Chonn A, Ducrest D, Baumann B, Belin D, Wohlwend A, Kiss JZ, Sappino AP, Tschopp J, Schifferli JA, Murine clusterin: molecular cloning and mRNA localization of a gene associated with epithelial differentiation processes during embryogenesis. J Cell Biol. 1993 Sep;122(5):1119-30 |
1* | J:167050 Khan QE, Press CM, Sehic A, Landin MA, Risnes S, Osmundsen H, Expression of prion gene and presence of prion protein during development of mouse molar tooth germ. Eur J Oral Sci. 2010 Dec;118(6):559-65 |
1 | J:188148 Landin MA, Shabestari M, Babaie E, Reseland JE, Osmundsen H, Gene Expression Profiling during Murine Tooth Development. Front Genet. 2012;3:139 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1 | J:135340 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia. BMC Dev Biol. 2008;8:2 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Cluh clustered mitochondria homolog (Synonyms: 1300001I01Rik) | |
Results | Reference |
2* | J:249661 Schatton D, Pla-Martin D, Marx MC, Hansen H, Mourier A, Nemazanyy I, Pessia A, Zentis P, Corona T, Kondylis V, Barth E, Schauss AC, Velagapudi V, Rugarli EI, CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol. 2017 Mar 06;216(3):675-693 |
Cma1 chymase 1, mast cell (Synonyms: Mcp-5, Mcp5, Mcpt5, MMCP-5) | |
Results | Reference |
2* | J:113235 Abraham D, Oster H, Huber M, Leitges M, The expression pattern of three mast cell specific proteases during mouse development. Mol Immunol. 2007 Feb;44(5):732-40 |
Cmklr1 chemerin chemokine-like receptor 1 (Synonyms: ChemR23, Gpcr27) | |
Results | Reference |
1* | J:39842 Methner A, Hermey G, Schinke B, Hermans-Borgmeyer I, A novel G protein-coupled receptor with homology to neuropeptide and chemoattractant receptors expressed during bone development. Biochem Biophys Res Commun. 1997 Apr 17;233(2):336-42 |
1* | J:319569 Ohira T, Spear D, Azimi N, Andreeva V, Yelick PC, Chemerin-ChemR23 signaling in tooth development. J Dent Res. 2012 Dec;91(12):1147-53 |
Cnbp cellular nucleic acid binding protein (Synonyms: Znf9) | |
Results | Reference |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Cnga2 cyclic nucleotide gated channel alpha 2 (Synonyms: Cnca, Cncg4, OCNC1) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Cnmd chondromodulin (Synonyms: Bricd3, Chmd, ChM-I, Chondromodulin 1, Lect1) | |
Results | Reference |
1 | J:188305 Ishijima M, Suzuki N, Hozumi K, Matsunobu T, Kosaki K, Kaneko H, Hassell JR, Arikawa-Hirasawa E, Yamada Y, Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation. Matrix Biol. 2012 May;31(4):234-45 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:182340 Michikami I, Fukushi T, Tanaka M, Egusa H, Maeda Y, Ooshima T, Wakisaka S, Abe M, Kruppel-like factor 4 regulates membranous and endochondral ossification. Exp Cell Res. 2012 Feb 15;318(4):311-25 |
2 | J:236002 Miura S, Kondo J, Takimoto A, Sano-Takai H, Guo L, Shukunami C, Tanaka H, Hiraki Y, The N-terminal cleavage of chondromodulin-I in growth-plate cartilage at the hypertrophic and calcified zones during bone development. PLoS One. 2014;9(4):e94239 |
2 | J:135068 Shukunami C, Takimoto A, Miura S, Nishizaki Y, Hiraki Y, Chondromodulin-I and tenomodulin are differentially expressed in the avascular mesenchyme during mouse and chick development. Cell Tissue Res. 2008 Apr;332(1):111-22 |
1 | J:274387 Yoshimoto Y, Takimoto A, Watanabe H, Hiraki Y, Kondoh G, Shukunami C, Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system. Sci Rep. 2017 Mar 22;7:45010 |
1 | J:115162 Yoshioka M, Yuasa S, Matsumura K, Kimura K, Shiomi T, Kimura N, Shukunami C, Okada Y, Mukai M, Shin H, Yozu R, Sata M, Ogawa S, Hiraki Y, Fukuda K, Chondromodulin-I maintains cardiac valvular function by preventing angiogenesis. Nat Med. 2006 Oct;12(10):1151-9 |
Cnn1 calponin 1 (Synonyms: calponin h1, CN, CnnI) | |
Results | Reference |
1 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
Cnn2 calponin 2 (Synonyms: Calpo2, h2-calponin) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Cnn3 calponin 3, acidic (Synonyms: 1600014M03Rik, Calpo3) | |
Results | Reference |
1 | J:289176 Maddala R, Mongan M, Xia Y, Rao PV, Calponin-3 deficiency augments contractile activity, plasticity, fibrogenic response and Yap/Taz transcriptional activation in lens epithelial cells and explants. Sci Rep. 2020 Jan 28;10(1):1295 |
1 | J:109567 Shen WB, Plachez C, Mongi AS, Richards LJ, Identification of candidate genes at the corticoseptal boundary during development. Gene Expr Patterns. 2006 Jun;6(5):471-81 |
Cnot3 CCR4-NOT transcription complex, subunit 3 (Synonyms: A930039N10Rik, MGC:40675) | |
Results | Reference |
1* | J:272586 Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, Yamamoto T, Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019 Feb 15;146(4):dev168146 |
Cnr1 cannabinoid receptor 1 (Synonyms: CB1, CB1R) | |
Results | Reference |
1 | J:192580 Diaz-Alonso J, Aguado T, Wu CS, Palazuelos J, Hofmann C, Garcez P, Guillemot F, Lu HC, Lutz B, Guzman M, Galve-Roperh I, The CB(1) cannabinoid receptor drives corticospinal motor neuron differentiation through the Ctip2/Satb2 transcriptional regulation axis. J Neurosci. 2012 Nov 21;32(47):16651-65 |
3 | J:165476 Keimpema E, Barabas K, Morozov YM, Tortoriello G, Torii M, Cameron G, Yanagawa Y, Watanabe M, Mackie K, Harkany T, Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding. J Neurosci. 2010 Oct 20;30(42):13992-4007 |
1 | J:227268 Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Bjorklund P, Mackie K, Di Marzo V, Hokfelt TG, Dobrzyn A, Harkany T, Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6185-94 |
2 | J:137203 Mulder J, Aguado T, Keimpema E, Barabas K, Ballester Rosado CJ, Nguyen L, Monory K, Marsicano G, Di Marzo V, Hurd YL, Guillemot F, Mackie K, Lutz B, Guzman M, Lu HC, Galve-Roperh I, Harkany T, Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning. Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8760-5 |
2 | J:143244 Vitalis T, Laine J, Simon A, Roland A, Leterrier C, Lenkei Z, The type 1 cannabinoid receptor is highly expressed in embryonic cortical projection neurons and negatively regulates neurite growth in vitro. Eur J Neurosci. 2008 Nov;28(9):1705-18 |
1 | J:171771 Wu CS, Zhu J, Wager-Miller J, Wang S, O'Leary D, Monory K, Lutz B, Mackie K, Lu HC, Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. Eur J Neurosci. 2010 Sep;32(5):693-706 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
Cnrip1 cannabinoid receptor interacting protein 1 (Synonyms: 1500041B16Rik, 3110054C06Rik, 5330437A18Rik) | |
Results | Reference |
1 | J:165476 Keimpema E, Barabas K, Morozov YM, Tortoriello G, Torii M, Cameron G, Yanagawa Y, Watanabe M, Mackie K, Harkany T, Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding. J Neurosci. 2010 Oct 20;30(42):13992-4007 |
Cntf ciliary neurotrophic factor | |
Results | Reference |
1 | J:105646 Oberle S, Schober A, Meyer V, Holtmann B, Henderson C, Sendtner M, Unsicker K, Loss of leukemia inhibitory factor receptor beta or cardiotrophin-1 causes similar deficits in preganglionic sympathetic neurons and adrenal medulla. J Neurosci. 2006 Feb 8;26(6):1823-32 |
1 | J:314320 Wang H, Kane AW, Lee C, Ahn S, Gli3 repressor controls cell fates and cell adhesion for proper establishment of neurogenic niche. Cell Rep. 2014 Aug 21;8(4):1093-104 |
Cntfr ciliary neurotrophic factor receptor (Synonyms: Cntfralpha) | |
Results | Reference |
2* | J:99504 de Bovis B, Derouet D, Gauchat JF, Elson G, Gascan H, Delapeyriere O, clc is co-expressed with clf or cntfr in developing mouse muscles. Cell Commun Signal. 2005 Jan 31;3(1):1 |
1 | J:105646 Oberle S, Schober A, Meyer V, Holtmann B, Henderson C, Sendtner M, Unsicker K, Loss of leukemia inhibitory factor receptor beta or cardiotrophin-1 causes similar deficits in preganglionic sympathetic neurons and adrenal medulla. J Neurosci. 2006 Feb 8;26(6):1823-32 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:314320 Wang H, Kane AW, Lee C, Ahn S, Gli3 repressor controls cell fates and cell adhesion for proper establishment of neurogenic niche. Cell Rep. 2014 Aug 21;8(4):1093-104 |
Cntn1 contactin 1 (Synonyms: CNTN, F3cam, usl) | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Cntn2 contactin 2 (Synonyms: axonin, D130012K04Rik, TAG-1, TAG1, Tax) | |
Results | Reference |
1 | J:121201 Chen L, Liao G, Waclaw RR, Burns KA, Linquist D, Campbell K, Zheng Y, Kuan CY, Rac1 controls the formation of midline commissures and the competency of tangential migration in ventral telencephalic neurons. J Neurosci. 2007 Apr 4;27(14):3884-93 |
1 | J:311814 Eom TY, Stanco A, Guo J, Wilkins G, Deslauriers D, Yan J, Monckton C, Blair J, Oon E, Perez A, Salas E, Oh A, Ghukasyan V, Snider WD, Rubenstein JL, Anton ES, Differential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration. Dev Cell. 2014 Dec 22;31(6):677-89 |
1 | J:157201 Eto K, Kawauchi T, Osawa M, Tabata H, Nakajima K, Role of dual leucine zipper-bearing kinase (DLK/MUK/ZPK) in axonal growth. Neurosci Res. 2010 Jan;66(1):37-45 |
1 | J:215584 Gil-Sanz C, Landeira B, Ramos C, Costa MR, Muller U, Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon. J Neurosci. 2014 Aug 6;34(32):10475-87 |
1 | J:330742 Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM, In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022 Oct 17;132(20):e156955 |
1 | J:105160 Guenette S, Chang Y, Hiesberger T, Richardson JA, Eckman CB, Eckman EA, Hammer RE, Herz J, Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. EMBO J. 2006 Jan 25;25(2):420-31 |
1 | J:119019 Gutin G, Fernandes M, Palazzolo L, Paek H, Yu K, Ornitz DM, McConnell SK, Hebert JM, FGF signalling generates ventral telencephalic cells independently of SHH. Development. 2006 Aug;133(15):2937-46 |
1* | J:91247 Hirata T, Suda Y, Nakao K, Narimatsu M, Hirano T, Hibi M, Zinc finger gene fez-like functions in the formation of subplate neurons and thalamocortical axons. Dev Dyn. 2004 Jul;230(3):546-56 |
2 | J:208050 Huang TN, Chuang HC, Chou WH, Chen CY, Wang HF, Chou SJ, Hsueh YP, Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality. Nat Neurosci. 2014 Feb;17(2):240-7 |
1 | J:94593 Inaki K, Nishimura S, Nakashiba T, Itohara S, Yoshihara Y, Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules. J Comp Neurol. 2004 Nov 15;479(3):243-56 |
1 | J:338359 Kaur N, Han W, Li Z, Madrigal MP, Shim S, Pochareddy S, Gulden FO, Li M, Xu X, Xing X, Takeo Y, Li Z, Lu K, Imamura Kawasawa Y, Ballester-Lurbe B, Moreno-Bravo JA, Chedotal A, Terrado J, Perez-Roger I, Koleske AJ, Sestan N, Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold. Neuron. 2020 Sep 23;107(6):1197-1211.e9 |
1* | J:99710 Kudo C, Ajioka I, Hirata Y, Nakajima K, Expression profiles of EphA3 at both the RNA and protein level in the developing mammalian forebrain. J Comp Neurol. 2005 Jul 4;487(3):255-69 |
1* | J:104312 Li HP, Oohira A, Ogawa M, Kawamura K, Kawano H, Aberrant trajectory of thalamocortical axons associated with abnormal localization of neurocan immunoreactivity in the cerebral neocortex of reeler mutant mice. Eur J Neurosci. 2005 Dec;22(11):2689-96 |
1* | J:69842 Lustig M, Erskine L, Mason CA, Grumet M, Sakurai T, Nr-CAM expression in the developing mouse nervous system: ventral midline structures, specific fiber tracts, and neuropilar regions. J Comp Neurol. 2001 May 21;434(1):13-28 |
1 | J:104532 Mendes SW, Henkemeyer M, Liebl DJ, Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J Neurosci. 2006 Jan 18;26(3):882-92 |
1 | J:238369 Mihalas AB, Elsen GE, Bedogni F, Daza RA, Ramos-Laguna KA, Arnold SJ, Hevner RF, Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity. Cell Rep. 2016 Jun 28;16(1):92-105 |
1* | J:74494 Nakashiba T, Nishimura S, Ikeda T, Itohara S, Complementary expression and neurite outgrowth activity of netrin-G subfamily members. Mech Dev. 2002 Feb;111(1-2):47-60 |
1 | J:110263 Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM, Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat Neurosci. 2006 Jun;9(6):787-97 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
1* | J:104160 Tole S, Gutin G, Bhatnagar L, Remedios R, Hebert JM, Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev Biol. 2006 Jan 1;289(1):141-51 |
1 | J:207603 Veleva-Rotse BO, Smart JL, Baas AF, Edmonds B, Zhao ZM, Brown A, Klug LR, Hansen K, Reilly G, Gardner AP, Subbiah K, Gaucher EA, Clevers H, Barnes AP, STRAD pseudokinases regulate axogenesis and LKB1 stability. Neural Dev. 2014;9:5 |
1* | J:18717 Wolfer DP, Henehan-Beatty A, Stoeckli ET, Sonderegger P, Lipp HP, Distribution of TAG-1/axonin-1 in fibre tracts and migratory streams of the developing mouse nervous system. J Comp Neurol. 1994 Jul 1;345(1):1-32 |
1 | J:294199 Zhu Y, Hirata T, Mackay F, Murakami F, Chemokine receptor CXCR7 non-cell-autonomously controls pontine neuronal migration and nucleus formation. Sci Rep. 2020 Jul 16;10(1):11830 |
Cntn3 contactin 3 (Synonyms: Pang) | |
Results | Reference |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Cntn5 contactin 5 (Synonyms: 6720426O10Rik, A830025P08Rik, LOC244683, NB-2) | |
Results | Reference |
1* | J:320376 Kleijer KTE, van Nieuwenhuize D, Spierenburg HA, Gregorio-Jordan S, Kas MJH, Burbach JPH, Structural abnormalities in the primary somatosensory cortex and a normal behavioral profile in Contactin-5 deficient mice. Cell Adh Migr. 2018 Jan 2;12(1):5-18 |
1 | J:180006 Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T, NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54 |
Cntn6 contactin 6 (Synonyms: NB-3) | |
Results | Reference |
1 | J:183955 Huang Z, Yu Y, Shimoda Y, Watanabe K, Liu Y, Loss of neural recognition molecule NB-3 delays the normal projection and terminal branching of developing corticospinal tract axons in the mouse. J Comp Neurol. 2012 Apr 15;520(6):1227-45 |
1* | J:271026 Zuko A, Oguro-Ando A, Post H, Taggenbrock RL, van Dijk RE, Altelaar AF, Heck AJ, Petrenko AG, van der Zwaag B, Shimoda Y, Pasterkamp RJ, Burbach JP, Association of Cell Adhesion Molecules Contactin-6 and Latrophilin-1 Regulates Neuronal Apoptosis. Front Mol Neurosci. 2016;9:143 |
Cntnap3 contactin associated protein-like 3 | |
Results | Reference |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
Cntnap4 contactin associated protein-like 4 (Synonyms: Caspr4, E130114F09Rik) | |
Results | Reference |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Cobl cordon-bleu WH2 repeat (Synonyms: C530045F18Rik, mKIAA0633) | |
Results | Reference |
1 | J:329940 Juan AM, Foong YH, Thorvaldsen JL, Lan Y, Leu NA, Rurik JG, Li L, Krapp C, Rosier CL, Epstein JA, Bartolomei MS, Tissue-specific Grb10/Ddc insulator drives allelic architecture for cardiac development. Mol Cell. 2022 Oct 6;82(19):3613-3631.e7 |
Coch cochlin (Synonyms: Coch-5B2, D12H14S564E) | |
Results | Reference |
1 | J:82307 Hulander M, Kiernan AE, Blomqvist SR, Carlsson P, Samuelsson EJ, Johansson BR, Steel KP, Enerback S, Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice. Development. 2003 May;130(9):2013-25 |
Col1a1 collagen, type I, alpha 1 (Synonyms: Col1a-1, Cola-1, Cola1, Mov-13) | |
Results | Reference |
2 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
2 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
1* | J:56413 Bachner D, Ahrens M, Betat N, Schroder D, Gross G, Developmental expression analysis of murine autotaxin (ATX). Mech Dev. 1999 Jun;84(1-2):121-5 |
1* | J:51222 Bachner D, Ahrens M, Schroder D, Hoffmann A, Lauber J, Betat N, Steinert P, Flohe L, Gross G, Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T1/2). Dev Dyn. 1998 Dec;213(4):398-411 |
1 | J:155396 Bellon E, Luyten FP, Tylzanowski P, delta-EF1 is a negative regulator of Ihh in the developing growth plate. J Cell Biol. 2009 Nov 30;187(5):685-99 |
2 | J:237340 Ben Shoham A, Rot C, Stern T, Krief S, Akiva A, Dadosh T, Sabany H, Lu Y, Kadler KE, Zelzer E, Deposition of collagen type I onto skeletal endothelium reveals a new role for blood vessels in regulating bone morphology. Development. 2016 Nov 01;143(21):3933-3943 |
1 | J:189073 Benazet JD, Pignatti E, Nugent A, Unal E, Laurent F, Zeller R, Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds. Development. 2012 Nov;139(22):4250-60 |
2 | J:311884 Berthet E, Chen C, Butcher K, Schneider RA, Alliston T, Amirtharajah M, Smad3 binds Scleraxis and Mohawk and regulates tendon matrix organization. J Orthop Res. 2013 Sep;31(9):1475-83 |
1 | J:183485 Chen D, Jarrell A, Guo C, Lang R, Atit R, Dermal beta-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation. Development. 2012 Apr;139(8):1522-33 |
1 | J:223357 Chen Q, Zhang L, de Crombrugghe B, Krahe R, Mesenchyme-specific overexpression of nucleolar protein 66 in mice inhibits skeletal growth and bone formation. FASEB J. 2015 Jun;29(6):2555-65 |
2* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1* | J:317044 Chen Y, Yang S, Lovisa S, Ambrose CG, McAndrews KM, Sugimoto H, Kalluri R, Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogenesis and Osteogenesis Imperfecta. Nat Commun. 2021 Dec 10;12(1):7199 |
2* | J:309441 Chien C, Pryce B, Tufa SF, Keene DR, Huang AH, Optimizing a 3D model system for molecular manipulation of tenogenesis. Connect Tissue Res. 2018 Jul;59(4):295-308 |
1 | J:218538 Coskun S, Chao H, Vasavada H, Heydari K, Gonzales N, Zhou X, de Crombrugghe B, Hirschi KK, Development of the fetal bone marrow niche and regulation of HSC quiescence and homing ability by emerging osteolineage cells. Cell Rep. 2014 Oct 23;9(2):581-90 |
1* | J:89221 Dacquin R, Mee PJ, Kawaguchi J, Olmsted-Davis EA, Gallagher JA, Nichols J, Lee K, Karsenty G, Smith A, Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar. Dev Dyn. 2004 Apr;229(4):826-34 |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1 | J:210100 Di Rocco F, Biosse Duplan M, Heuze Y, Kaci N, Komla-Ebri D, Munnich A, Mugniery E, Benoist-Lasselin C, Legeai-Mallet L, FGFR3 mutation causes abnormal membranous ossification in achondroplasia. Hum Mol Genet. 2014 Jun 1;23(11):2914-25 |
1 | J:237001 Duan X, Bradbury SR, Olsen BR, Berendsen AD, VEGF stimulates intramembranous bone formation during craniofacial skeletal development. Matrix Biol. 2016 May-Jul;52-54:127-40 |
1 | J:194118 Fantauzzo KA, Kurban M, Levy B, Christiano AM, Trps1 and its target gene Sox9 regulate epithelial proliferation in the developing hair follicle and are associated with hypertrichosis. PLoS Genet. 2012;8(11):e1003002 |
1 | J:312814 Fernandez Vallone V, Leprovots M, Ribatallada-Soriano D, Gerbier R, Lefort A, Libert F, Vassart G, Garcia MI, LGR5 controls extracellular matrix production by stem cells in the developing intestine. EMBO Rep. 2020 Jul 3;21(7):e49224 |
2* | J:166807 Fortunati D, Reppe S, Fjeldheim AK, Nielsen M, Gautvik VT, Gautvik KM, Periostin is a collagen associated bone matrix protein regulated by parathyroid hormone. Matrix Biol. 2010 Sep;29(7):594-601 |
1 | J:347133 Funato N, Srivastava D, Shibata S, Yanagisawa H, TBX1 Regulates Chondrocyte Maturation in the Spheno-occipital Synchondrosis. J Dent Res. 2020 Sep;99(10):1182-1191 |
2 | J:185118 Galli GG, Honnens de Lichtenberg K, Carrara M, Hans W, Wuelling M, Mentz B, Multhaupt HA, Fog CK, Jensen KT, Rappsilber J, Vortkamp A, Coulton L, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Calogero RA, Couchman JR, Lund AH, Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone. PLoS Genet. 2012 May;8(5):e1002711 |
1 | J:151466 Gamer LW, Cox K, Carlo JM, Rosen V, Overexpression of BMP3 in the developing skeleton alters endochondral bone formation resulting in spontaneous rib fractures. Dev Dyn. 2009 Aug 3;238(9):2374-2381 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1* | J:85546 Gill SE, Pape MC, Khokha R, Watson AJ, Leco KJ, A null mutation for tissue inhibitor of metalloproteinases-3 (Timp-3) impairs murine bronchiole branching morphogenesis. Dev Biol. 2003 Sep 15;261(2):313-23 |
1 | J:98430 Glass DA 2nd, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G, Canonical wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell. 2005 May;8(5):751-64 |
2 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
2 | J:195895 Hanson KP, Jung JP, Tran QA, Hsu SP, Iida R, Ajeti V, Campagnola PJ, Eliceiri KW, Squirrell JM, Lyons GE, Ogle BM, Spatial and temporal analysis of extracellular matrix proteins in the developing murine heart: a blueprint for regeneration. Tissue Eng Part A. 2013 May;19(9-10):1132-43 |
1* | J:163483 He G, Tavella S, Hanley KP, Self M, Oliver G, Grifone R, Hanley N, Ward C, Bobola N, Inactivation of Six2 in mouse identifies a novel genetic mechanism controlling development and growth of the cranial base. Dev Biol. 2010 Aug 15;344(2):720-30 |
1 | J:114686 Hinoi E, Bialek P, Chen YT, Rached MT, Groner Y, Behringer RR, Ornitz DM, Karsenty G, Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes Dev. 2006 Nov 1;20(21):2937-42 |
1 | J:267950 Holzman MA, Bergmann JM, Feldman M, Landry-Truchon K, Jeannotte L, Mansfield JH, HOXA5 protein expression and genetic fate mapping show lineage restriction in the developing musculoskeletal system. Int J Dev Biol. 2018;62(11-12):785-796 |
1 | J:237341 Houben A, Kostanova-Poliakova D, Weissenbock M, Graf J, Teufel S, von der Mark K, Hartmann C, beta-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis. Development. 2016 Oct 15;143(20):3826-3838 |
1 | J:231474 Hung IH, Schoenwolf GC, Lewandoski M, Ornitz DM, A combined series of Fgf9 and Fgf18 mutant alleles identifies unique and redundant roles in skeletal development. Dev Biol. 2016 Mar 1;411(1):72-84 |
1 | J:122952 Hung IH, Yu K, Lavine KJ, Ornitz DM, FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. Dev Biol. 2007 Jul 15;307(2):300-13 |
2 | J:242713 Ikeda Y, Zabbarova I, Schaefer CM, Bushnell D, De Groat WC, Kanai A, Bates CM, Fgfr2 is integral for bladder mesenchyme patterning and function. Am J Physiol Renal Physiol. 2017 Apr 01;312(4):F607-F618 |
1 | J:155543 Inose H, Ochi H, Kimura A, Fujita K, Xu R, Sato S, Iwasaki M, Sunamura S, Takeuchi Y, Fukumoto S, Saito K, Nakamura T, Siomi H, Ito H, Arai Y, Shinomiya K, Takeda S, A microRNA regulatory mechanism of osteoblast differentiation. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20794-9 |
1 | J:119288 Jacob AL, Smith C, Partanen J, Ornitz DM, Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation. Dev Biol. 2006 Aug 15;296(2):315-28 |
1 | J:306540 Jiang D, Correa-Gallegos D, Christ S, Stefanska A, Liu J, Ramesh P, Rajendran V, De Santis MM, Wagner DE, Rinkevich Y, Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring. Nat Cell Biol. 2018 Apr;20(4):422-431 |
1* | J:300574 Jiang Q, Qin X, Yoshida CA, Komori H, Yamana K, Ohba S, Hojo H, Croix BS, Kawata-Matsuura VKS, Komori T, Antxr1, Which is a Target of Runx2, Regulates Chondrocyte Proliferation and Apoptosis. Int J Mol Sci. 2020 Mar 31;21(7):2425 |
1 | J:143940 Kimura H, Kwan KM, Zhang Z, Deng JM, Darnay BG, Behringer RR, Nakamura T, de Crombrugghe B, Akiyama H, Cthrc1 is a positive regulator of osteoblastic bone formation. PLoS One. 2008;3(9):e3174 |
1 | J:319475 Liao C, Lu M, Hong Y, Mao C, Chen J, Ren C, Lin M, Chen W, Osteogenic and angiogenic profiles of the palatal process of the maxilla and the palatal process of the palatine bone. J Anat. 2022 Feb;240(2):385-397 |
1 | J:175747 Liu W, Watson SS, Lan Y, Keene DR, Ovitt CE, Liu H, Schweitzer R, Jiang R, The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis. Mol Cell Biol. 2010 Oct;30(20):4797-807 |
1 | J:119882 Liu Z, Lavine KJ, Hung IH, Ornitz DM, FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate. Dev Biol. 2007 Feb 1;302(1):80-91 |
1 | J:125095 Lu J, Lian G, Lenkinski R, De Grand A, Vaid RR, Bryce T, Stasenko M, Boskey A, Walsh C, Sheen V, Filamin B mutations cause chondrocyte defects in skeletal development. Hum Mol Genet. 2007 Jul 15;16(14):1661-75 |
1 | J:152843 Luo J, Zhou W, Zhou X, Li D, Weng J, Yi Z, Cho SG, Li C, Yi T, Wu X, Li XY, de Crombrugghe B, Hook M, Liu M, Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development. 2009 Aug;136(16):2747-56 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1* | J:74493 Maes C, Carmeliet P, Moermans K, Stockmans I, Smets N, Collen D, Bouillon R, Carmeliet G, Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF(164) and VEGF(188). Mech Dev. 2002 Feb;111(1-2):61-73 |
1* | J:34539 Marvulli D, Volpin D, Bressan GM, Spatial and temporal changes of type VI collagen expression during mouse development. Dev Dyn. 1996 Aug;206(4):447-54 |
1 | J:197791 Masago Y, Hosoya A, Kawasaki K, Kawano S, Nasu A, Toguchida J, Fujita K, Nakamura H, Kondoh G, Nagata K, The molecular chaperone Hsp47 is essential for cartilage and endochondral bone formation. J Cell Sci. 2012 Mar 1;125(Pt 5):1118-28 |
1 | J:296737 Matsuura VKSK, Yoshida CA, Komori H, Sakane C, Yamana K, Jiang Q, Komori T, Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice. Int J Mol Sci. 2020 Apr 12;21(8):2682 |
1 | J:88344 Miao D, Liu H, Plut P, Niu M, Huo R, Goltzman D, Henderson JE, Impaired endochondral bone development and osteopenia in Gli2-deficient mice. Exp Cell Res. 2004 Mar 10;294(1):210-22 |
1 | J:149225 Miclea RL, Karperien M, Bosch CA, van der Horst G, van der Valk MA, Kobayashi T, Kronenberg HM, Rawadi G, Akcakaya P, Lowik CW, Fodde R, Wit JM, Robanus-Maandag EC, Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors. BMC Dev Biol. 2009;9:26 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:74344 Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B, The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 2002 Jan 11;108(1):17-29 |
1* | J:74179 Nikaido T, Yokoya S, Mori T, Hagino S, Iseki K, Zhang Y, Takeuchi M, Takaki H, Kikuchi S, Wanaka A, Expression of the novel transcription factor OASIS, which belongs to the CREB/ATF family, in mouse embryo with special reference to bone development. Histochem Cell Biol. 2001 Aug;116(2):141-8 |
1 | J:165333 Nishikawa K, Nakashima T, Takeda S, Isogai M, Hamada M, Kimura A, Kodama T, Yamaguchi A, Owen MJ, Takahashi S, Takayanagi H, Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation. J Clin Invest. 2010 Oct 1;120(10):3455-65 |
2 | J:232190 Noda K, Kitami M, Kitami K, Kaku M, Komatsu Y, Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development. Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2589-97 |
2 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1 | J:258274 Patra D, DeLassus E, Mueller J, Abou-Ezzi G, Sandell LJ, Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice. Biol Open. 2018 Feb 22;7(2):bio032094 |
1 | J:40590 Perala M, Savontaus M, Metsaranta M, Vuorio E, Developmental regulation of mRNA species for types II, IX and XI collagens during mouse embryogenesis. Biochem J. 1997 May 15;324(Pt 1):209-16 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
1* | J:356701 Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD, Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr;91(4):387-93 |
1 | J:299239 Qin X, Jiang Q, Nagano K, Moriishi T, Miyazaki T, Komori H, Ito K, Mark KV, Sakane C, Kaneko H, Komori T, Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts. PLoS Genet. 2020 Nov;16(11):e1009169 |
1* | J:320343 Randilini A, Fujikawa K, Shibata S, An in situ hybridization study of decorin and biglycan mRNA in mouse osteoblasts in vivo. Anat Sci Int. 2021 Mar;96(2):265-272 |
1* | J:73681 Saika S, Saika S, Liu CY, Azhar M, Sanford LP, Doetschman T, Gendron RL, Kao CW, Kao WW, TGFbeta2 in corneal morphogenesis during mouse embryonic development. Dev Biol. 2001 Dec 15;240(2):419-32 |
1* | J:7142 Schnieke A, Harbers K, Jaenisch R, Embryonic lethal mutation in mice induced by retrovirus insertion into the alpha 1(I) collagen gene. Nature. 1983 Jul 28-Aug 3;304(5924):315-20 |
1* | J:143455 Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Al Awqati Q, Ballabio A, Karsenty G, Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification. Genes Dev. 2008 Oct 1;22(19):2645-50 |
1* | J:146224 Staverosky JA, Pryce BA, Watson SS, Schweitzer R, Tubulin polymerization-promoting protein family member 3, Tppp3, is a specific marker of the differentiating tendon sheath and synovial joints. Dev Dyn. 2009 Mar;238(3):685-92 |
1 | J:191584 Sueyoshi T, Yamamoto K, Akiyama H, Conditional deletion of Tgfbr2 in hypertrophic chondrocytes delays terminal chondrocyte differentiation. Matrix Biol. 2012 Jul;31(6):352-9 |
1 | J:333326 Suh J, Kim NK, Shim W, Lee SH, Kim HJ, Moon E, Sesaki H, Jang JH, Kim JE, Lee YS, Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab. 2023 Feb 7;35(2):345-360.e7 |
1 | J:238410 Sun C, Berry WL, Olson LE, PDGFRalpha controls the balance of stromal and adipogenic cells during adipose tissue organogenesis. Development. 2017 Jan 01;144(1):83-94 |
1 | J:287435 Sun P, He L, Jia K, Yue Z, Li S, Jin Y, Li Z, Siwko S, Xue F, Su J, Liu M, Luo J, Regulation of body length and bone mass by Gpr126/Adgrg6. Sci Adv. 2020 Mar;6(12):eaaz0368 |
1* | J:67784 Takeda S, Bonnamy JP, Owen MJ, Ducy P, Karsenty G, Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. Genes Dev. 2001 Feb 15;15(4):467-81 |
2* | J:36919 Tanaka Y, Kobayashi K, Kita M, Masuda H, Kinoshita S, Nagata K, Imanishi J, Expression of 47 kDa heat shock protein (HSP47) during development of mouse cornea. Exp Eye Res. 1996 Oct;63(4):383-93 |
1 | J:125052 Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H, Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification. Mol Cell Biol. 2007 Aug;27(16):5650-63 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1 | J:302296 Vong KI, Ma TC, Li B, Leung TCN, Nong W, Ngai SM, Hui JHL, Jiang L, Kwan KM, SOX9-COL9A3-dependent regulation of choroid plexus epithelial polarity governs blood-cerebrospinal fluid barrier integrity. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2009568118 |
1 | J:354236 Wada S, Ideno H, Nakashima K, Komatsu K, Demura N, Tomonari H, Kimura H, Tachibana M, Nifuji A, The histone H3K9 methyltransferase G9a regulates tendon formation during development. Sci Rep. 2024 Sep 5;14(1):20771 |
1* | J:320688 Wada S, Ideno H, Shimada A, Kamiunten T, Nakamura Y, Nakashima K, Kimura H, Shinkai Y, Tachibana M, Nifuji A, H3K9MTase G9a is essential for the differentiation and growth of tenocytes in vitro. Histochem Cell Biol. 2015 Jul;144(1):13-20 |
1* | J:341382 Wu B, Wu B, Benkaci S, Shi L, Lu P, Park T, Morrow BE, Wang Y, Zhou B, Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development. J Am Heart Assoc. 2023 Sep 19;12(18):e029683 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1 | J:331058 Xu J, Liu H, Lan Y, Jiang R, The transcription factors Foxf1 and Foxf2 integrate the SHH, HGF and TGFbeta signaling pathways to drive tongue organogenesis. Development. 2022 Nov 1;149(21):dev200667 |
1* | J:307192 Yadav PS, Feng S, Cong Q, Kim H, Liu Y, Yang Y, Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118 |
1 | J:320311 Yang L, Gu S, Ye W, Song Y, Chen Y, Augmented Indian hedgehog signaling in cranial neural crest cells leads to craniofacial abnormalities and dysplastic temporomandibular joint in mice. Cell Tissue Res. 2016 Apr;364(1):105-15 |
1 | J:274387 Yoshimoto Y, Takimoto A, Watanabe H, Hiraki Y, Kondoh G, Shukunami C, Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system. Sci Rep. 2017 Mar 22;7:45010 |
1* | J:28954 Yoshioka H, Iyama K, Inoguchi K, Khaleduzzaman M, Ninomiya Y, Ramirez F, Developmental pattern of expression of the mouse alpha 1 (XI) collagen gene (Col11a1). Dev Dyn. 1995 Sep;204(1):41-7 |
1* | J:334015 Yoshioka H, Komura S, Kuramitsu N, Goto A, Hasegawa T, Amizuka N, Ishimoto T, Ozasa R, Nakano T, Imai Y, Akiyama H, Deletion of Tfam in Prx1-Cre expressing limb mesenchyme results in spontaneous bone fractures. J Bone Miner Metab. 2022 Sep;40(5):839-852 |
2 | J:329949 Yuan H, Xie B, Yu X, Lin C, Li M, Zhang Y, Zou X, Lu M, Zhao M, Wen X, A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development. Front Physiol. 2022;13:981311 |
1* | J:75934 Zelzer E, McLean W, Ng YS, Fukai N, Reginato AM, Lovejoy S, D'Amore PA, Olsen BR, Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development. 2002 Apr;129(8):1893-904 |
1 | J:358835 Zhang J, Gao J, Zeng X, Wang Z, Chen C, Rong C, Li S, Cai L, Wang L, Zhang L, Tian Z, A novel Cdc42-YAP-fibronectin signaling axis regulates ameloblast differentiation during early enamel formation. Biochim Biophys Acta Mol Basis Dis. 2024 Nov 14;1871(2):167570 |
2 | J:125580 Zhang L, Deng M, Kao CW, Kao WW, Xia Y, MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis. Mol Vis. 2003 Nov 3;9:584-93 |
Col1a2 collagen, type I, alpha 2 (Synonyms: Col1a-2, Cola-2, Cola2) | |
Results | Reference |
2 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
1* | J:272619 Aydogdu N, Rudat C, Trowe MO, Kaiser M, Ludtke TH, Taketo MM, Christoffels VM, Moon A, Kispert A, TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827 |
1 | J:189073 Benazet JD, Pignatti E, Nugent A, Unal E, Laurent F, Zeller R, Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds. Development. 2012 Nov;139(22):4250-60 |
1 | J:311884 Berthet E, Chen C, Butcher K, Schneider RA, Alliston T, Amirtharajah M, Smad3 binds Scleraxis and Mohawk and regulates tendon matrix organization. J Orthop Res. 2013 Sep;31(9):1475-83 |
1 | J:359854 Cano-Carrillo S, Garcia-Padilla C, Aranega AE, Lozano-Velasco E, Franco D, Mef2c- and Nkx2-5-Divergent Transcriptional Regulation of Chick WT1_76127 and Mouse Gm14014 lncRNAs and Their Implication in Epicardial Cell Migration. Int J Mol Sci. 2024 Nov 30;25(23) |
1* | J:317044 Chen Y, Yang S, Lovisa S, Ambrose CG, McAndrews KM, Sugimoto H, Kalluri R, Type-I collagen produced by distinct fibroblast lineages reveals specific function during embryogenesis and Osteogenesis Imperfecta. Nat Commun. 2021 Dec 10;12(1):7199 |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1 | J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767 |
1 | J:210100 Di Rocco F, Biosse Duplan M, Heuze Y, Kaci N, Komla-Ebri D, Munnich A, Mugniery E, Benoist-Lasselin C, Legeai-Mallet L, FGFR3 mutation causes abnormal membranous ossification in achondroplasia. Hum Mol Genet. 2014 Jun 1;23(11):2914-25 |
1 | J:237001 Duan X, Bradbury SR, Olsen BR, Berendsen AD, VEGF stimulates intramembranous bone formation during craniofacial skeletal development. Matrix Biol. 2016 May-Jul;52-54:127-40 |
2 | J:185118 Galli GG, Honnens de Lichtenberg K, Carrara M, Hans W, Wuelling M, Mentz B, Multhaupt HA, Fog CK, Jensen KT, Rappsilber J, Vortkamp A, Coulton L, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Calogero RA, Couchman JR, Lund AH, Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone. PLoS Genet. 2012 May;8(5):e1002711 |
1 | J:151466 Gamer LW, Cox K, Carlo JM, Rosen V, Overexpression of BMP3 in the developing skeleton alters endochondral bone formation resulting in spontaneous rib fractures. Dev Dyn. 2009 Aug 3;238(9):2374-2381 |
1* | J:85546 Gill SE, Pape MC, Khokha R, Watson AJ, Leco KJ, A null mutation for tissue inhibitor of metalloproteinases-3 (Timp-3) impairs murine bronchiole branching morphogenesis. Dev Biol. 2003 Sep 15;261(2):313-23 |
1 | J:98430 Glass DA 2nd, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G, Canonical wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell. 2005 May;8(5):751-64 |
1 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:195895 Hanson KP, Jung JP, Tran QA, Hsu SP, Iida R, Ajeti V, Campagnola PJ, Eliceiri KW, Squirrell JM, Lyons GE, Ogle BM, Spatial and temporal analysis of extracellular matrix proteins in the developing murine heart: a blueprint for regeneration. Tissue Eng Part A. 2013 May;19(9-10):1132-43 |
1 | J:122952 Hung IH, Yu K, Lavine KJ, Ornitz DM, FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. Dev Biol. 2007 Jul 15;307(2):300-13 |
1 | J:306540 Jiang D, Correa-Gallegos D, Christ S, Stefanska A, Liu J, Ramesh P, Rajendran V, De Santis MM, Wagner DE, Rinkevich Y, Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring. Nat Cell Biol. 2018 Apr;20(4):422-431 |
1 | J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522 |
1 | J:188148 Landin MA, Shabestari M, Babaie E, Reseland JE, Osmundsen H, Gene Expression Profiling during Murine Tooth Development. Front Genet. 2012;3:139 |
1 | J:319475 Liao C, Lu M, Hong Y, Mao C, Chen J, Ren C, Lin M, Chen W, Osteogenic and angiogenic profiles of the palatal process of the maxilla and the palatal process of the palatine bone. J Anat. 2022 Feb;240(2):385-397 |
1 | J:175747 Liu W, Watson SS, Lan Y, Keene DR, Ovitt CE, Liu H, Schweitzer R, Jiang R, The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis. Mol Cell Biol. 2010 Oct;30(20):4797-807 |
1 | J:119882 Liu Z, Lavine KJ, Hung IH, Ornitz DM, FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate. Dev Biol. 2007 Feb 1;302(1):80-91 |
1 | J:125095 Lu J, Lian G, Lenkinski R, De Grand A, Vaid RR, Bryce T, Stasenko M, Boskey A, Walsh C, Sheen V, Filamin B mutations cause chondrocyte defects in skeletal development. Hum Mol Genet. 2007 Jul 15;16(14):1661-75 |
1 | J:88344 Miao D, Liu H, Plut P, Niu M, Huo R, Goltzman D, Henderson JE, Impaired endochondral bone development and osteopenia in Gli2-deficient mice. Exp Cell Res. 2004 Mar 10;294(1):210-22 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1* | J:73681 Saika S, Saika S, Liu CY, Azhar M, Sanford LP, Doetschman T, Gendron RL, Kao CW, Kao WW, TGFbeta2 in corneal morphogenesis during mouse embryonic development. Dev Biol. 2001 Dec 15;240(2):419-32 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1 | J:311811 Trowe MO, Airik R, Weiss AC, Farin HF, Foik AB, Bettenhausen E, Schuster-Gossler K, Taketo MM, Kispert A, Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter. Development. 2012 Sep;139(17):3099-108 |
1* | J:284147 Velecela V, Torres-Cano A, Garcia-Melero A, Ramiro-Pareta M, Muller-Sanchez C, Segarra-Mondejar M, Chau YY, Campos-Bonilla B, Reina M, Soriano FX, Hastie ND, Martinez FO, Martinez-Estrada OM, Epicardial cell shape and maturation are regulated by Wt1 via transcriptional control of Bmp4. Development. 2019 Oct 17;146(20):dev178723 |
1* | J:341382 Wu B, Wu B, Benkaci S, Shi L, Lu P, Park T, Morrow BE, Wang Y, Zhou B, Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development. J Am Heart Assoc. 2023 Sep 19;12(18):e029683 |
1 | J:331058 Xu J, Liu H, Lan Y, Jiang R, The transcription factors Foxf1 and Foxf2 integrate the SHH, HGF and TGFbeta signaling pathways to drive tongue organogenesis. Development. 2022 Nov 1;149(21):dev200667 |
1 | J:320311 Yang L, Gu S, Ye W, Song Y, Chen Y, Augmented Indian hedgehog signaling in cranial neural crest cells leads to craniofacial abnormalities and dysplastic temporomandibular joint in mice. Cell Tissue Res. 2016 Apr;364(1):105-15 |
1 | J:358835 Zhang J, Gao J, Zeng X, Wang Z, Chen C, Rong C, Li S, Cai L, Wang L, Zhang L, Tian Z, A novel Cdc42-YAP-fibronectin signaling axis regulates ameloblast differentiation during early enamel formation. Biochim Biophys Acta Mol Basis Dis. 2024 Nov 14;1871(2):167570 |
2 | J:125580 Zhang L, Deng M, Kao CW, Kao WW, Xia Y, MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis. Mol Vis. 2003 Nov 3;9:584-93 |
Col2a1 collagen, type II, alpha 1 (Synonyms: Col2, Col2a, Col2a-1, Del1, Lpk, M100413, M100856, Rgsc413, Rgsc856) | |
Results | Reference |
1 | J:124269 Abzhanov A, Rodda SJ, McMahon AP, Tabin CJ, Regulation of skeletogenic differentiation in cranial dermal bone. Development. 2007 Sep;134(17):3133-44 |
1 | J:90567 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 2004 May 1;18(9):1072-87 |
1 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
1* | J:4067 Andrikopoulos K, Suzuki HR, Solursh M, Ramirez F, Localization of pro-alpha 2(V) collagen transcripts in the tissues of the developing mouse embryo. Dev Dyn. 1992 Oct;195(2):113-20 |
1 | J:284333 Arai HN, Sato F, Yamamoto T, Woltjen K, Kiyonari H, Yoshimoto Y, Shukunami C, Akiyama H, Kist R, Sehara-Fujisawa A, Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate. Cell Rep. 2019 Oct 15;29(3):603-616.e5 |
1 | J:67299 Arikawa-Hirasawa E, Watanabe H, Takami H, Hassell JR, Yamada Y, Perlecan is essential for cartilage and cephalic development. Nat Genet. 1999 Nov;23(3):354-8 |
1 | J:119152 Arnold MA, Kim Y, Czubryt MP, Phan D, McAnally J, Qi X, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN, MEF2C transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell. 2007 Mar;12(3):377-89 |
1* | J:56413 Bachner D, Ahrens M, Betat N, Schroder D, Gross G, Developmental expression analysis of murine autotaxin (ATX). Mech Dev. 1999 Jun;84(1-2):121-5 |
1 | J:155396 Bellon E, Luyten FP, Tylzanowski P, delta-EF1 is a negative regulator of Ihh in the developing growth plate. J Cell Biol. 2009 Nov 30;187(5):685-99 |
1 | J:189073 Benazet JD, Pignatti E, Nugent A, Unal E, Laurent F, Zeller R, Smad4 is required to induce digit ray primordia and to initiate the aggregation and differentiation of chondrogenic progenitors in mouse limb buds. Development. 2012 Nov;139(22):4250-60 |
1 | J:156015 Blitz E, Viukov S, Sharir A, Shwartz Y, Galloway JL, Pryce BA, Johnson RL, Tabin CJ, Schweitzer R, Zelzer E, Bone ridge patterning during musculoskeletal assembly is mediated through SCX regulation of Bmp4 at the tendon-skeleton junction. Dev Cell. 2009 Dec;17(6):861-73 |
2* | J:32246 Cheah KS, Lau ET, Au PK, Tam PP, Expression of the mouse alpha 1(II) collagen gene is not restricted to cartilage during development. Development. 1991 Apr;111(4):945-53 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:251599 Chen W, Chen L, Zhang Z, Meng F, Huang G, Sheng P, Zhang Z, Liao W, MicroRNA-455-3p modulates cartilage development and degeneration through modification of histone H3 acetylation. Biochim Biophys Acta. 2016 Dec;1863(12):2881-2891 |
2* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:232617 Chen Z, Yue SX, Zhou G, Greenfield EM, Murakami S, ERK1 and ERK2 regulate chondrocyte terminal differentiation during endochondral bone formation. J Bone Miner Res. 2015 May;30(5):765-74 |
1* | J:309441 Chien C, Pryce B, Tufa SF, Keene DR, Huang AH, Optimizing a 3D model system for molecular manipulation of tenogenesis. Connect Tissue Res. 2018 Jul;59(4):295-308 |
1 | J:327334 Choi KY, Lee SW, Park MH, Bae YC, Shin HI, Nam S, Kim YJ, Kim HJ, Ryoo HM, Spatio-temporal expression patterns of Runx2 isoforms in early skeletogenesis. Exp Mol Med. 2002 Dec 31;34(6):426-33 |
1 | J:107668 Cobb J, Dierich A, Huss-Garcia Y, Duboule D, A mouse model for human short-stature syndromes identifies Shox2 as an upstream regulator of Runx2 during long-bone development. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4511-5 |
1* | J:89221 Dacquin R, Mee PJ, Kawaguchi J, Olmsted-Davis EA, Gallagher JA, Nichols J, Lee K, Karsenty G, Smith A, Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar. Dev Dyn. 2004 Apr;229(4):826-34 |
1 | J:230611 Dierker T, Bachvarova V, Krause Y, Li JP, Kjellen L, Seidler DG, Vortkamp A, Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones. Matrix Biol. 2016 Jan;49:82-92 |
1 | J:237001 Duan X, Bradbury SR, Olsen BR, Berendsen AD, VEGF stimulates intramembranous bone formation during craniofacial skeletal development. Matrix Biol. 2016 May-Jul;52-54:127-40 |
1 | J:293351 Eyal S, Kult S, Rubin S, Krief S, Felsenthal N, Pineault KM, Leshkowitz D, Salame TM, Addadi Y, Wellik DM, Zelzer E, Bone morphology is regulated modularly by global and regional genetic programs. Development. 2019 Jul 26;146(14):dev167882 |
1 | J:272612 Eyal S, Rubin S, Krief S, Levin L, Zelzer E, Common cellular origin and diverging developmental programs for different sesamoid bones. Development. 2019 Feb 28;146(4):dev167452 |
1* | J:360528 Fritzsch B, Weng X, Yamoah EN, Qin T, Hui CC, Lebron-Mora L, Pavlinkova G, Sham MH, Irx3/5 Null Deletion in Mice Blocks Cochlea-Saccule Segregation and Disrupts the Auditory Tonotopic Map. J Comp Neurol. 2024 Dec;532(12):e70008 |
1 | J:74145 Gori F, Schipani E, Demay MB, Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development. J Cell Biochem. 2001 Apr 2-27;82(1):46-57 |
2* | J:215404 Hering TM, Wirthlin L, Ravindran S, McAlinden A, Changes in type II procollagen isoform expression during chondrogenesis by disruption of an alternative 5' splice site within Col2a1 exon 2. Matrix Biol. 2014 Jun;36:51-63 |
1 | J:104933 Hilton MJ, Gutierrez L, Martinez DA, Wells DE, EXT1 regulates chondrocyte proliferation and differentiation during endochondral bone development. Bone. 2005 Mar;36(3):379-86 |
1 | J:114686 Hinoi E, Bialek P, Chen YT, Rached MT, Groner Y, Behringer RR, Ornitz DM, Karsenty G, Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes Dev. 2006 Nov 1;20(21):2937-42 |
1 | J:260150 Hisanaga S, Miyake M, Taniuchi S, Oyadomari M, Morimoto M, Sato R, Hirose J, Mizuta H, Oyadomari S, PERK-mediated translational control is required for collagen secretion in chondrocytes. Sci Rep. 2018 Jan 15;8(1):773 |
1 | J:196289 Huegel J, Mundy C, Sgariglia F, Nygren P, Billings PC, Yamaguchi Y, Koyama E, Pacifici M, Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: A mechanism likely deranged in Hereditary Multiple Exostoses. Dev Biol. 2013 May 1;377(1):100-12 |
1 | J:231474 Hung IH, Schoenwolf GC, Lewandoski M, Ornitz DM, A combined series of Fgf9 and Fgf18 mutant alleles identifies unique and redundant roles in skeletal development. Dev Biol. 2016 Mar 1;411(1):72-84 |
1 | J:109399 Ichikawa Y, Sumi M, Ohwatari N, Komori T, Sumi T, Shibata H, Furuichi T, Yamaguchi A, Nakamura T, Evaluation of 9.4-T MR microimaging in assessing normal and defective fetal bone development: comparison of MR imaging and histological findings. Bone. 2004 Apr;34(4):619-28 |
2* | J:194983 Ideno H, Shimada A, Imaizumi K, Kimura H, Abe M, Nakashima K, Nifuji A, Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development. Gene Expr Patterns. 2013 Mar-Apr;13(3-4):84-90 |
1 | J:81856 Ihanamaki T, Saamanen AM, Suominen J, Pelliniemi LJ, Harley V, Vuorio E, Salminen H, Expression of Sox9 and type IIA procollagen during ocular development and aging in transgenic Del1 mice with a mutation in the type II collagen gene. Eur J Ophthalmol. 2002 Nov-Dec;12(6):450-8 |
1 | J:80671 Ihanamaki T, Salminen H, Saamanen AM, Sandberg-Lall M, Vuorio E, Pelliniemi LJ, Ultrastructural characterization of developmental and degenerative vitreo-retinal changes in the eyes of transgenic mice with a deletion mutation in type II collagen gene. Curr Eye Res. 2002 Jun;24(6):439-50 |
1* | J:140470 Imuta Y, Nishioka N, Kiyonari H, Sasaki H, Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124). Dev Dyn. 2008 Dec 18;238(1):210-222 |
1 | J:153633 Ito T, Yadav N, Lee J, Furumatsu T, Yamashita S, Yoshida K, Taniguchi N, Hashimoto M, Tsuchiya M, Ozaki T, Lotz M, Bedford MT, Asahara H, Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC Dev Biol. 2009;9:47 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:233766 Jiang Q, Qin X, Kawane T, Komori H, Matsuo Y, Taniuchi I, Ito K, Izumi S, Komori T, Cbfb2 Isoform Dominates More Potent Cbfb1 and Is Required for Skeletal Development. J Bone Miner Res. 2016 Jul;31(7):1391-404 |
1* | J:300574 Jiang Q, Qin X, Yoshida CA, Komori H, Yamana K, Ohba S, Hojo H, Croix BS, Kawata-Matsuura VKS, Komori T, Antxr1, Which is a Target of Runx2, Regulates Chondrocyte Proliferation and Apoptosis. Int J Mol Sci. 2020 Mar 31;21(7):2425 |
1 | J:148688 Kahn J, Shwartz Y, Blitz E, Krief S, Sharir A, Breitel DA, Rattenbach R, Relaix F, Maire P, Rountree RB, Kingsley DM, Zelzer E, Muscle contraction is necessary to maintain joint progenitor cell fate. Dev Cell. 2009 May;16(5):734-43 |
1 | J:143089 Kanauchi Y, Takahara M, Harada M, Ogino T, Growth of severely hypoplastic phalanges and metacarpals in symbrachydactyly: an experimental study in mice. J Hand Surg Am. 2008 Nov;33(9):1589-96 |
1 | J:295492 Kawai M, Herrmann D, Fuchs A, Cheng S, Ferrer-Vaquer A, Gotz R, Driller K, Neubuser A, Ohura K, Fgfr1 conditional-knockout in neural crest cells induces heterotopic chondrogenesis and osteogenesis in mouse frontal bones. Med Mol Morphol. 2019 Sep;52(3):156-163 |
2 | J:155442 Kawaki H, Kubota S, Suzuki A, Lazar N, Yamada T, Matsumura T, Ohgawara T, Maeda T, Perbal B, Lyons KM, Takigawa M, Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage. J Bone Miner Res. 2008 Nov;23(11):1751-64 |
1 | J:143940 Kimura H, Kwan KM, Zhang Z, Deng JM, Darnay BG, Behringer RR, Nakamura T, de Crombrugghe B, Akiyama H, Cthrc1 is a positive regulator of osteoblastic bone formation. PLoS One. 2008;3(9):e3174 |
1* | J:158147 Kinoshita M, Era T, Jakt LM, Nishikawa S, The novel protein kinase Vlk is essential for stromal function of mesenchymal cells. Development. 2009 Jun;136(12):2069-79 |
1 | J:348423 Kitamura A, Yamamoto M, Hirouchi H, Watanabe G, Taniguchi S, Sekiya S, Ishizuka S, Jeong J, Higa K, Yamashita S, Abe S, Downregulation of SOX9 expression in developing entheses adjacent to intramembranous bone. PLoS One. 2024;19(5):e0301080 |
1 | J:140779 Kolpakova-Hart E, Nicolae C, Zhou J, Olsen BR, Col2-Cre recombinase is co-expressed with endogenous type II collagen in embryonic renal epithelium and drives development of polycystic kidney disease following inactivation of ciliary genes. Matrix Biol. 2008 Jul;27(6):505-12 |
1 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
2* | J:184499 Lewis R, Ravindran S, Wirthlin L, Traeger G, Fernandes RJ, McAlinden A, Disruption of the developmentally-regulated Col2a1 pre-mRNA alternative splicing switch in a transgenic knock-in mouse model. Matrix Biol. 2012 Apr;31(3):214-26 |
1 | J:208830 Lin SS, Tzeng BH, Lee KR, Smith RJ, Campbell KP, Chen CC, Cav3.2 T-type calcium channel is required for the NFAT-dependent Sox9 expression in tracheal cartilage. Proc Natl Acad Sci U S A. 2014 May 13;111(19):E1990-8 |
1 | J:352094 Liu C, Zhou N, Li N, Xu T, Chen X, Zhou H, Xie A, Liu H, Zhu L, Wang S, Xiao J, Disrupted tenogenesis in masseter as a potential cause of micrognathia. Int J Oral Sci. 2022 Oct 18;14(1):50 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1 | J:125095 Lu J, Lian G, Lenkinski R, De Grand A, Vaid RR, Bryce T, Stasenko M, Boskey A, Walsh C, Sheen V, Filamin B mutations cause chondrocyte defects in skeletal development. Hum Mol Genet. 2007 Jul 15;16(14):1661-75 |
1 | J:152843 Luo J, Zhou W, Zhou X, Li D, Weng J, Yi Z, Cho SG, Li C, Yi T, Wu X, Li XY, de Crombrugghe B, Hook M, Liu M, Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development. 2009 Aug;136(16):2747-56 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1 | J:233282 Maes C, Araldi E, Haigh K, Khatri R, Van Looveren R, Giaccia AJ, Haigh JJ, Carmeliet G, Schipani E, VEGF-independent cell-autonomous functions of HIF-1alpha regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival. J Bone Miner Res. 2012 Mar;27(3):596-609 |
1 | J:193853 Makino Y, Takahashi Y, Tanabe R, Tamamura Y, Watanabe T, Haraikawa M, Hamagaki M, Hata K, Kanno J, Yoneda T, Saga Y, Goseki-Sone M, Kaneko K, Yamaguchi A, Iimura T, Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone. 2013 Mar;53(1):248-58 |
1 | J:197791 Masago Y, Hosoya A, Kawasaki K, Kawano S, Nasu A, Toguchida J, Fujita K, Nakamura H, Kondoh G, Nagata K, The molecular chaperone Hsp47 is essential for cartilage and endochondral bone formation. J Cell Sci. 2012 Mar 1;125(Pt 5):1118-28 |
1 | J:91587 Mates L, Nicolae C, Morgelin M, Deak F, Kiss I, Aszodi A, Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities. Matrix Biol. 2004 Jun;23(3):195-204 |
1 | J:296737 Matsuura VKSK, Yoshida CA, Komori H, Sakane C, Yamana K, Jiang Q, Komori T, Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice. Int J Mol Sci. 2020 Apr 12;21(8):2682 |
1 | J:149225 Miclea RL, Karperien M, Bosch CA, van der Horst G, van der Valk MA, Kobayashi T, Kronenberg HM, Rawadi G, Akcakaya P, Lowik CW, Fodde R, Wit JM, Robanus-Maandag EC, Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors. BMC Dev Biol. 2009;9:26 |
1 | J:205339 Mis EK, Liem KF Jr, Kong Y, Schwartz NB, Domowicz M, Weatherbee SD, Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length. Dev Biol. 2014 Jan 1;385(1):67-82 |
1 | J:318774 Monemdjou R, Vasheghani F, Fahmi H, Perez G, Blati M, Taniguchi N, Lotz M, St-Arnaud R, Pelletier JP, Martel-Pelletier J, Beier F, Kapoor M, Association of cartilage-specific deletion of peroxisome proliferator-activated receptor gamma with abnormal endochondral ossification and impaired cartilage growth and development in a murine model. Arthritis Rheum. 2012 May;64(5):1551-61 |
1 | J:170582 Mundy C, Yasuda T, Kinumatsu T, Yamaguchi Y, Iwamoto M, Enomoto-Iwamoto M, Koyama E, Pacifici M, Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine. Dev Biol. 2011 Mar 1;351(1):70-81 |
1 | J:316165 Nakamura E, Hata K, Takahata Y, Kurosaka H, Abe M, Abe T, Kihara M, Komori T, Kobayashi S, Murakami T, Inubushi T, Yamashiro T, Yamamoto S, Akiyama H, Kawaguchi M, Sakata N, Nishimura R, Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice. Commun Biol. 2021 Nov 3;4(1):1258 |
1 | J:85095 Nakashima K, de Crombrugghe B, Transcriptional mechanisms in osteoblast differentiation and bone formation. Trends Genet. 2003 Aug;19(8):458-66 |
1* | J:74344 Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B, The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 2002 Jan 11;108(1):17-29 |
1 | J:255459 Nara M, Kitamura K, Yamamoto M, Nagakura R, Mitomo K, Matsunaga S, Abe S, Developmental mechanism of muscle-tendon-bone complex in the fetal soft palate. Arch Oral Biol. 2017 Oct;82:71-78 |
3* | J:14821 Ng LJ, Tam PP, Cheah KS, Preferential expression of alternatively spliced mRNAs encoding type II procollagen with a cysteine-rich amino-propeptide in differentiating cartilage and nonchondrogenic tissues during early mouse development. Dev Biol. 1993 Oct;159(2):403-17 |
1* | J:38926 Ng LJ, Wheatley S, Muscat GE, Conway-Campbell J, Bowles J, Wright E , Bell DM , Tam PP , Cheah KS , Koopman P, SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse. Dev Biol. 1997 Mar 1;183(1):108-21 |
1* | J:317046 Niebler S, Schubert T, Hunziker EB, Bosserhoff AK, Activating enhancer binding protein 2 epsilon (AP-2epsilon)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development. Arthritis Res Ther. 2015 May 12;17:119 |
1 | J:316655 Oh SK, Shin JO, Baek JI, Lee J, Bae JW, Ankamerddy H, Kim MJ, Huh TL, Ryoo ZY, Kim UK, Bok J, Lee KY, Pannexin 3 is required for normal progression of skeletal development in vertebrates. FASEB J. 2015 Nov;29(11):4473-84 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1* | J:265842 Palagano E, Zuccarini G, Prontera P, Borgatti R, Stangoni G, Elisei S, Mantero S, Menale C, Forlino A, Uva P, Oppo M, Vezzoni P, Villa A, Merlo GR, Sobacchi C, Mutations in the Neuroblastoma Amplified Sequence gene in a family affected by Acrofrontofacionasal Dysostosis type 1. Bone. 2018 Sep;114:125-136 |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
1 | J:258274 Patra D, DeLassus E, Mueller J, Abou-Ezzi G, Sandell LJ, Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice. Biol Open. 2018 Feb 22;7(2):bio032094 |
1 | J:84742 Pavlov MI, Sautier JM, Oboeuf M, Asselin A, Berdal A, Chondrogenic differentiation during midfacial development in the mouse: in vivo and in vitro studies. Biol Cell. 2003;95(2):75-86 |
1 | J:40590 Perala M, Savontaus M, Metsaranta M, Vuorio E, Developmental regulation of mRNA species for types II, IX and XI collagens during mouse embryogenesis. Biochem J. 1997 May 15;324(Pt 1):209-16 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
1* | J:199462 Probst S, Zeller R, Zuniga A, The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development. Differentiation. 2013 Apr-Jun;85(4-5):121-30 |
1 | J:128917 Provot S, Nachtrab G, Paruch J, Chen AP, Silva A, Kronenberg HM, A-raf and B-raf are dispensable for normal endochondral bone development, and parathyroid hormone-related peptide suppresses extracellular signal-regulated kinase activation in hypertrophic chondrocytes. Mol Cell Biol. 2008 Jan;28(1):344-57 |
1 | J:219841 Qin X, Jiang Q, Matsuo Y, Kawane T, Komori H, Moriishi T, Taniuchi I, Ito K, Kawai Y, Rokutanda S, Izumi S, Komori T, Cbfb regulates bone development by stabilizing runx family proteins. J Bone Miner Res. 2015 Apr;30(4):706-14 |
1 | J:299239 Qin X, Jiang Q, Nagano K, Moriishi T, Miyazaki T, Komori H, Ito K, Mark KV, Sakane C, Kaneko H, Komori T, Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts. PLoS Genet. 2020 Nov;16(11):e1009169 |
1* | J:84724 Rahkonen O, Savontaus M, Abdelwahid E, Vuorio E, Jokinen E, Expression patterns of cartilage collagens and Sox9 during mouse heart development. Histochem Cell Biol. 2003 Aug;120(2):103-10 |
1 | J:238878 Ray A, Singh PN, Sohaskey ML, Harland RM, Bandyopadhyay A, Precise spatial restriction of BMP signaling is essential for articular cartilage differentiation. Development. 2015 Mar 15;142(6):1169-79 |
1 | J:76480 Robledo RF, Rajan L, Li X, Lufkin T, The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev. 2002 May 1;16(9):1089-101 |
1* | J:116229 Roulet M, Ruggiero F, Karsenty G, Leguellec D, A comprehensive study of the spatial and temporal expression of the col5a1 gene in mouse embryos: a clue for understanding collagen V function in developing connective tissues. Cell Tissue Res. 2007 Feb;327(2):323-32 |
1 | J:124105 Ruiz-Perez VL, Blair HJ, Rodriguez-Andres ME, Blanco MJ, Wilson A, Liu YN, Miles C, Peters H, Goodship JA, Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. Development. 2007 Aug;134(16):2903-12 |
1 | J:142447 Sato S, Kimura A, Ozdemir J, Asou Y, Miyazaki M, Jinno T, Ae K, Liu X, Osaki M, Takeuchi Y, Fukumoto S, Kawaguchi H, Haro H, Shinomiya K, Karsenty G, Takeda S, The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration: Findings in murine models and in human disease. Arthritis Rheum. 2008 Sep;58(9):2764-75 |
3* | J:39853 Savontaus M, Ihanamaki T, Metsaranta M, Vuorio E, Sandberg-Lall M, Localization of type II collagen mRNA isoforms in the developing eyes of normal and transgenic mice with a mutation in type II collagen gene. Invest Ophthalmol Vis Sci. 1997 Apr;38(5):930-42 |
1* | J:44842 Savontaus M, Metsaranta M, Vuorio E, Mutation in type II collagen gene disturbs spinal development and gene expression patterns in transgenic Del1 mice. Lab Invest. 1997 Dec;77(6):591-600 |
1* | J:37148 Savontaus M, Metsranta M, Vuorio E, Retarded skeletal development in transgenic mice with a type II collagen mutation. Am J Pathol. 1996 Dec;149(6):2169-82 |
2 | J:95068 Savontaus M, Rintala-Jamsa M, Morko J, Ronning O, Metsaranta M, Vuorio E, Abnormal craniofacial development and expression patterns of extracellular matrix components in transgenic Del1 mice harboring a deletion mutation in the type II collagen gene. Orthod Craniofac Res. 2004 Nov;7(4):216-26 |
1* | J:207837 Schmid R, Bosserhoff AK, Redundancy in regulation of chondrogenesis in MIA/CD-RAP-deficient mice. Mech Dev. 2014 Feb;131:24-34 |
1 | J:279005 Schroeder N, Wuelling M, Hoffmann D, Brand-Saberi B, Vortkamp A, Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bones. PLoS One. 2019;14(8):e0218230 |
1* | J:143455 Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Al Awqati Q, Ballabio A, Karsenty G, Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification. Genes Dev. 2008 Oct 1;22(19):2645-50 |
1* | J:83132 Settle SH Jr, Rountree RB, Sinha A, Thacker A, Higgins K, Kingsley DM, Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes. Dev Biol. 2003 Feb 1;254(1):116-30 |
1* | J:45403 Shibata S, Fukada K, Suzuki S, Yamashita Y, Immunohistochemistry of collagen types II and X, and enzyme-histochemistry of alkaline phosphatase in the developing condylar cartilage of the fetal mouse mandible. J Anat. 1997 Nov;191(Pt 4):561-70 |
1 | J:141868 Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H, Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9. J Biol Chem. 2008 Sep 5;283(36):24682-9 |
1 | J:119736 Shiota M, Heike T, Haruyama M, Baba S, Tsuchiya A, Fujino H, Kobayashi H, Kato T, Umeda K, Yoshimoto M, Nakahata T, Isolation and characterization of bone marrow-derived mesenchymal progenitor cells with myogenic and neuronal properties. Exp Cell Res. 2007 Mar 10;313(5):1008-23 |
1 | J:253985 Singh PNP, Yadav US, Azad K, Goswami P, Kinare V, Bandyopadhyay A, NFIA and GATA3 are crucial regulators of embryonic articular cartilage differentiation. Development. 2018 Jan 17;145(2):dev156554 |
2 | J:95959 Smith N, Dong Y, Lian JB, Pratap J, Kingsley PD, van Wijnen AJ, Stein JL, Schwarz EM, O'keefe RJ, Stein GS, Drissi MH, Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. J Cell Physiol. 2005 Apr;203(1):133-43 |
1 | J:134924 Spagnoli A, O'Rear L, Chandler RL, Granero-Molto F, Mortlock DP, Gorska AE, Weis JA, Longobardi L, Chytil A, Shimer K, Moses HL, TGF-beta signaling is essential for joint morphogenesis. J Cell Biol. 2007 Jun 18;177(6):1105-17 |
1* | J:57297 St-Jacques B, Hammerschmidt M, McMahon AP, Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation [published erratum appears in Genes Dev 1999 Oct 1;13(19):2617]. Genes Dev. 1999 Aug 15;13(16):2072-86 |
1* | J:146224 Staverosky JA, Pryce BA, Watson SS, Schweitzer R, Tubulin polymerization-promoting protein family member 3, Tppp3, is a specific marker of the differentiating tendon sheath and synovial joints. Dev Dyn. 2009 Mar;238(3):685-92 |
1 | J:191584 Sueyoshi T, Yamamoto K, Akiyama H, Conditional deletion of Tgfbr2 in hypertrophic chondrocytes delays terminal chondrocyte differentiation. Matrix Biol. 2012 Jul;31(6):352-9 |
1* | J:139013 Takatalo M, Jarvinen E, Laitinen S, Thesleff I, Ronnholm R, Expression of the novel Golgi protein GoPro49 is developmentally regulated during mesenchymal differentiation. Dev Dyn. 2008 Aug;237(8):2243-55 |
1* | J:67784 Takeda S, Bonnamy JP, Owen MJ, Ducy P, Karsenty G, Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. Genes Dev. 2001 Feb 15;15(4):467-81 |
1* | J:62593 Tanaka K, Matsumoto Y, Nakatani F, Iwamoto Y, Yamada Y, A zinc finger transcription factor, alphaA-crystallin binding protein 1, is a negative regulator of the chondrocyte-specific enhancer of the alpha1(II) collagen gene. (Retraction and replacement of Figures 1D and 7 appear in 2006; 26(13):5202). Mol Cell Biol. 2000 Jun;20(12):4428-35 |
1 | J:84273 Terpstra L, Prud'homme J, Arabian A, Takeda S, Karsenty G, Dedhar S, St-Arnaud R, Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes. J Cell Biol. 2003 Jul 7;162(1):139-48 |
1 | J:112372 Tsumaki N, Nakase T, Miyaji T, Kakiuchi M, Kimura T, Ochi T, Yoshikawa H, Bone morphogenetic protein signals are required for cartilage formation and differently regulate joint development during skeletogenesis. J Bone Miner Res. 2002 May;17(5):898-906 |
1* | J:209518 Ushijima T, Okazaki K, Tsushima H, Iwamoto Y, CCAAT/enhancer-binding protein beta regulates the repression of type II collagen expression during the differentiation from proliferative to hypertrophic chondrocytes. J Biol Chem. 2014 Jan 31;289(5):2852-63 |
1 | J:172689 Wang M, Jin H, Tang D, Huang S, Zuscik MJ, Chen D, Smad1 plays an essential role in bone development and postnatal bone formation. Osteoarthritis Cartilage. 2011 Jun;19(6):751-62 |
1* | J:154906 Wang W, Lian N, Li L, Moss HE, Wang W, Perrien DS, Elefteriou F, Yang X, Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription. Development. 2009 Dec;136(24):4143-53 |
1 | J:177115 Wang Y, Liu C, Rohr J, Liu H, He F, Yu J, Sun C, Li L, Gu S, Chen Y, Tissue interaction is required for glenoid fossa development during temporomandibular joint formation. Dev Dyn. 2011 Nov;240(11):2466-73 |
1 | J:113656 Wang Y, Nishida S, Sakata T, Elalieh HZ, Chang W, Halloran BP, Doty SB, Bikle DD, Insulin-like growth factor-I is essential for embryonic bone development. Endocrinology. 2006 Oct;147(10):4753-61 |
1 | J:101174 Wang Y, Xiao R, Yang F, Karim BO, Iacovelli AJ, Cai J, Lerner CP, Richtsmeier JT, Leszl JM, Hill CA, Yu K, Ornitz DM, Elisseeff J, Huso DL, Jabs EW, Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse. Development. 2005 Aug;132(15):3537-48 |
1* | J:200760 Wang Y, Zheng Y, Chen D, Chen Y, Enhanced BMP signaling prevents degeneration and leads to endochondral ossification of Meckel's cartilage in mice. Dev Biol. 2013 Sep 15;381(2):301-11 |
1 | J:172737 Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RA, Peterson AS, Solloway MJ, Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol. 2011 May 30;193(5):935-51 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1 | J:281388 Xu J, Huang Z, Wang W, Tan X, Li H, Zhang Y, Tian W, Hu T, Chen YP, FGF8 Signaling Alters the Osteogenic Cell Fate in the Hard Palate. J Dent Res. 2018 May;97(5):589-596 |
1* | J:307192 Yadav PS, Feng S, Cong Q, Kim H, Liu Y, Yang Y, Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118 |
1* | J:99592 Yamaguchi K, Matsuo N, Sumiyoshi H, Fujimoto N, Iyama KI, Yanagisawa S, Yoshioka H, Pro-alpha3(V) collagen chain is expressed in bone and its basic N-terminal peptide adheres to osteosarcoma cells. Matrix Biol. 2005 Jun;24(4):283-94 |
1 | J:320311 Yang L, Gu S, Ye W, Song Y, Chen Y, Augmented Indian hedgehog signaling in cranial neural crest cells leads to craniofacial abnormalities and dysplastic temporomandibular joint in mice. Cell Tissue Res. 2016 Apr;364(1):105-15 |
1 | J:360708 Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K, Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase. Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2320070121 |
1* | J:28954 Yoshioka H, Iyama K, Inoguchi K, Khaleduzzaman M, Ninomiya Y, Ramirez F, Developmental pattern of expression of the mouse alpha 1 (XI) collagen gene (Col11a1). Dev Dyn. 1995 Sep;204(1):41-7 |
1 | J:202210 Zhang X, Ting K, Pathmanathan D, Ko T, Chen W, Chen F, Lee H, James AW, Siu RK, Shen J, Culiat CT, Soo C, Calvarial cleidocraniodysplasia-like defects with ENU-induced Nell-1 deficiency. J Craniofac Surg. 2012 Jan;23(1):61-6 |
1 | J:172282 Zhou ZQ, Shung CY, Ota S, Akiyama H, Keene DR, Hurlin PJ, Sequential and coordinated actions of c-Myc and N-Myc control appendicular skeletal development. PLoS One. 2011;6(4):e18795 |
Col3a1 collagen, type III, alpha 1 (Synonyms: Col3a-1, Tsk-2, Tsk2) | |
Results | Reference |
1 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
2 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:195895 Hanson KP, Jung JP, Tran QA, Hsu SP, Iida R, Ajeti V, Campagnola PJ, Eliceiri KW, Squirrell JM, Lyons GE, Ogle BM, Spatial and temporal analysis of extracellular matrix proteins in the developing murine heart: a blueprint for regeneration. Tissue Eng Part A. 2013 May;19(9-10):1132-43 |
2 | J:242713 Ikeda Y, Zabbarova I, Schaefer CM, Bushnell D, De Groat WC, Kanai A, Bates CM, Fgfr2 is integral for bladder mesenchyme patterning and function. Am J Physiol Renal Physiol. 2017 Apr 01;312(4):F607-F618 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:176019 Luo R, Jeong SJ, Jin Z, Strokes N, Li S, Piao X, G protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and lamination. Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12925-30 |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
1 | J:40590 Perala M, Savontaus M, Metsaranta M, Vuorio E, Developmental regulation of mRNA species for types II, IX and XI collagens during mouse embryogenesis. Biochem J. 1997 May 15;324(Pt 1):209-16 |
1* | J:284147 Velecela V, Torres-Cano A, Garcia-Melero A, Ramiro-Pareta M, Muller-Sanchez C, Segarra-Mondejar M, Chau YY, Campos-Bonilla B, Reina M, Soriano FX, Hastie ND, Martinez FO, Martinez-Estrada OM, Epicardial cell shape and maturation are regulated by Wt1 via transcriptional control of Bmp4. Development. 2019 Oct 17;146(20):dev178723 |
Col4a1 collagen, type IV, alpha 1 (Synonyms: alpha1(IV) collagen, Bru, Col4a-1, Del(8)44H, Del(8)Bru44H, Raw, Svc) | |
Results | Reference |
2 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
1 | J:150527 Bai X, Dilworth DJ, Weng YC, Gould DB, Developmental distribution of collagen IV isoforms and relevance to ocular diseases. Matrix Biol. 2009 May;28(4):194-201 |
1 | J:327292 Bakhti M, Bastidas-Ponce A, Tritschler S, Czarnecki O, Tarquis-Medina M, Nedvedova E, Jaki J, Willmann SJ, Scheibner K, Cota P, Salinno C, Boldt K, Horn N, Ueffing M, Burtscher I, Theis FJ, Coskun U, Lickert H, Synaptotagmin-13 orchestrates pancreatic endocrine cell egression and islet morphogenesis. Nat Commun. 2022 Aug 4;13(1):4540 |
1* | J:253196 Dubail J, Vasudevan D, Wang LW, Earp SE, Jenkins MW, Haltiwanger RS, Apte SS, Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome. Sci Rep. 2016 Sep 30;6:33974 |
1* | J:30369 Enders GC, Kahsai TZ, Lian G, Funabiki K, Killen PD, Hudson BG, Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis. Biol Reprod. 1995 Dec;53(6):1489-99 |
1 | J:195895 Hanson KP, Jung JP, Tran QA, Hsu SP, Iida R, Ajeti V, Campagnola PJ, Eliceiri KW, Squirrell JM, Lyons GE, Ogle BM, Spatial and temporal analysis of extracellular matrix proteins in the developing murine heart: a blueprint for regeneration. Tissue Eng Part A. 2013 May;19(9-10):1132-43 |
2 | J:347708 Lartey NL, van der Ent M, Alonzo R, Chen D, King PD, A temporally-restricted pattern of endothelial cell collagen 4 alpha 1 expression during embryonic development determined with a novel knockin Col4a1-P2A-eGFP mouse line. Genesis. 2024 Feb;62(1):e23539 |
2 | J:315454 Loscertales M, Nicolaou F, Jeanne M, Longoni M, Gould DB, Sun Y, Maalouf FI, Nagy N, Donahoe PK, Type IV collagen drives alveolar epithelial-endothelial association and the morphogenetic movements of septation. BMC Biol. 2016 Jul 13;14:59 |
1 | J:241849 Ma S, Santhosh D, Kumar T P, Huang Z, A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis. Dev Cell. 2017 May 22;41(4):366-381.e4 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:251718 Pietila I, Prunskaite-Hyyrylainen R, Kaisto S, Tika E, van Eerde AM, Salo AM, Garma L, Miinalainen I, Feitz WF, Bongers EM, Juffer A, Knoers NV, Renkema KY, Myllyharju J, Vainio SJ, Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning. PLoS One. 2016;11(1):e0147171 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:361964 Wang M, Liu H, Zhang M, Niu X, Sun M, Wang F, Ni Y, Hong T, Zhang W, Dang S, The secreted protease ADAMTS18 links early isoform transformation and maturation of glomerular basement membrane macromolecules to the integrity of the glomerular filtration barrier. Biochem Biophys Res Commun. 2025 Mar 1;750:151386 |
1* | J:33225 Wu JE, Santoro SA, Differential expression of integrin alpha subunits supports distinct roles during lung branching morphogenesis. Dev Dyn. 1996 Jun;206(2):169-81 |
Col4a2 collagen, type IV, alpha 2 (Synonyms: Col4a-2, MGC:7371) | |
Results | Reference |
1 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
1 | J:150527 Bai X, Dilworth DJ, Weng YC, Gould DB, Developmental distribution of collagen IV isoforms and relevance to ocular diseases. Matrix Biol. 2009 May;28(4):194-201 |
1* | J:30369 Enders GC, Kahsai TZ, Lian G, Funabiki K, Killen PD, Hudson BG, Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis. Biol Reprod. 1995 Dec;53(6):1489-99 |
1 | J:185218 Hall-Glenn F, De Young RA, Huang BL, van Handel B, Hofmann JJ, Chen TT, Choi A, Ong JR, Benya PD, Mikkola H, Iruela-Arispe ML, Lyons KM, CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PLoS One. 2012;7(2):e30562 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:251718 Pietila I, Prunskaite-Hyyrylainen R, Kaisto S, Tika E, van Eerde AM, Salo AM, Garma L, Miinalainen I, Feitz WF, Bongers EM, Juffer A, Knoers NV, Renkema KY, Myllyharju J, Vainio SJ, Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning. PLoS One. 2016;11(1):e0147171 |
1 | J:35512 Rothman TP, Chen J, Howard MJ, Costantini F, Schuchardt A, Pachnis V, Gershon MD, Increased expression of laminin-1 and collagen (IV) subunits in the aganglionic bowel of ls/ls, but not c-ret -/- mice. Dev Biol. 1996 Sep 15;178(2):498-513 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1* | J:33225 Wu JE, Santoro SA, Differential expression of integrin alpha subunits supports distinct roles during lung branching morphogenesis. Dev Dyn. 1996 Jun;206(2):169-81 |
Col4a3 collagen, type IV, alpha 3 (Synonyms: alpha3(IV), tumstatin) | |
Results | Reference |
1 | J:150527 Bai X, Dilworth DJ, Weng YC, Gould DB, Developmental distribution of collagen IV isoforms and relevance to ocular diseases. Matrix Biol. 2009 May;28(4):194-201 |
1* | J:30369 Enders GC, Kahsai TZ, Lian G, Funabiki K, Killen PD, Hudson BG, Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis. Biol Reprod. 1995 Dec;53(6):1489-99 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:251718 Pietila I, Prunskaite-Hyyrylainen R, Kaisto S, Tika E, van Eerde AM, Salo AM, Garma L, Miinalainen I, Feitz WF, Bongers EM, Juffer A, Knoers NV, Renkema KY, Myllyharju J, Vainio SJ, Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning. PLoS One. 2016;11(1):e0147171 |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
Col4a4 collagen, type IV, alpha 4 (Synonyms: [a]4(IV), E130010M05Rik) | |
Results | Reference |
1 | J:150527 Bai X, Dilworth DJ, Weng YC, Gould DB, Developmental distribution of collagen IV isoforms and relevance to ocular diseases. Matrix Biol. 2009 May;28(4):194-201 |
1 | J:306061 Damen M, Wirtz L, Soroka E, Khatif H, Kukat C, Simons BD, Bazzi H, High proliferation and delamination during skin epidermal stratification. Nat Commun. 2021 May 28;12(1):3227 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
Col4a5 collagen, type IV, alpha 5 | |
Results | Reference |
1 | J:150527 Bai X, Dilworth DJ, Weng YC, Gould DB, Developmental distribution of collagen IV isoforms and relevance to ocular diseases. Matrix Biol. 2009 May;28(4):194-201 |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
Col4a6 collagen, type IV, alpha 6 | |
Results | Reference |
1 | J:150527 Bai X, Dilworth DJ, Weng YC, Gould DB, Developmental distribution of collagen IV isoforms and relevance to ocular diseases. Matrix Biol. 2009 May;28(4):194-201 |
1 | J:263002 Komori T, Ono M, Hara ES, Ueda J, Nguyen HTT, Nguyen HT, Yonezawa T, Maeba T, Kimura-Ono A, Takarada T, Momota R, Maekawa K, Kuboki T, Oohashi T, Type IV collagen alpha6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium. Sci Rep. 2018 Feb 8;8(1):2612 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
1* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
Col5a1 collagen, type V, alpha 1 | |
Results | Reference |
1 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
1 | J:175747 Liu W, Watson SS, Lan Y, Keene DR, Ovitt CE, Liu H, Schweitzer R, Jiang R, The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis. Mol Cell Biol. 2010 Oct;30(20):4797-807 |
1* | J:116229 Roulet M, Ruggiero F, Karsenty G, Leguellec D, A comprehensive study of the spatial and temporal expression of the col5a1 gene in mouse embryos: a clue for understanding collagen V function in developing connective tissues. Cell Tissue Res. 2007 Feb;327(2):323-32 |
1* | J:310487 Xiang C, Frietze KK, Bi Y, Li Y, Dal Pozzo V, Pal S, Alexander N, Baubet V, D'Acunto V, Mason CE, Davuluri RV, Dahmane N, RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons. Mol Cell Biol. 2021 Jun 23;41(7):e0052620 |
3* | J:99592 Yamaguchi K, Matsuo N, Sumiyoshi H, Fujimoto N, Iyama KI, Yanagisawa S, Yoshioka H, Pro-alpha3(V) collagen chain is expressed in bone and its basic N-terminal peptide adheres to osteosarcoma cells. Matrix Biol. 2005 Jun;24(4):283-94 |
Col5a2 collagen, type V, alpha 2 (Synonyms: 1110014L14Rik) | |
Results | Reference |
1* | J:4067 Andrikopoulos K, Suzuki HR, Solursh M, Ramirez F, Localization of pro-alpha 2(V) collagen transcripts in the tissues of the developing mouse embryo. Dev Dyn. 1992 Oct;195(2):113-20 |
1 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
1 | J:175747 Liu W, Watson SS, Lan Y, Keene DR, Ovitt CE, Liu H, Schweitzer R, Jiang R, The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis. Mol Cell Biol. 2010 Oct;30(20):4797-807 |
Col5a3 collagen, type V, alpha 3 (Synonyms: Pro-alpha3(V)) | |
Results | Reference |
3* | J:99592 Yamaguchi K, Matsuo N, Sumiyoshi H, Fujimoto N, Iyama KI, Yanagisawa S, Yoshioka H, Pro-alpha3(V) collagen chain is expressed in bone and its basic N-terminal peptide adheres to osteosarcoma cells. Matrix Biol. 2005 Jun;24(4):283-94 |
Col6a1 collagen, type VI, alpha 1 (Synonyms: Col6a-1) | |
Results | Reference |
1 | J:141191 Braghetta P, Ferrari A, Fabbro C, Bizzotto D, Volpin D, Bonaldo P, Bressan GM, An enhancer required for transcription of the Col6a1 gene in muscle connective tissue is induced by signals released from muscle cells. Exp Cell Res. 2008 Nov 15;314(19):3508-18 |
1* | J:46232 Klewer SE, Krob SL, Kolker SJ, Kitten GT, Expression of type VI collagen in the developing mouse heart. Dev Dyn. 1998 Mar;211(3):248-55 |
2* | J:34539 Marvulli D, Volpin D, Bressan GM, Spatial and temporal changes of type VI collagen expression during mouse development. Dev Dyn. 1996 Aug;206(4):447-54 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1* | J:284147 Velecela V, Torres-Cano A, Garcia-Melero A, Ramiro-Pareta M, Muller-Sanchez C, Segarra-Mondejar M, Chau YY, Campos-Bonilla B, Reina M, Soriano FX, Hastie ND, Martinez FO, Martinez-Estrada OM, Epicardial cell shape and maturation are regulated by Wt1 via transcriptional control of Bmp4. Development. 2019 Oct 17;146(20):dev178723 |
Col6a2 collagen, type VI, alpha 2 (Synonyms: Col6a-2) | |
Results | Reference |
1* | J:46232 Klewer SE, Krob SL, Kolker SJ, Kitten GT, Expression of type VI collagen in the developing mouse heart. Dev Dyn. 1998 Mar;211(3):248-55 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Col6a3 collagen, type VI, alpha 3 (Synonyms: Col6a-3) | |
Results | Reference |
1 | J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132 |
1* | J:46232 Klewer SE, Krob SL, Kolker SJ, Kitten GT, Expression of type VI collagen in the developing mouse heart. Dev Dyn. 1998 Mar;211(3):248-55 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Col6a4 collagen, type VI, alpha 4 (Synonyms: 1110001D15Rik, Dvwa, EG235580, Vwa6) | |
Results | Reference |
1* | J:173590 Nakajima M, Miyamoto Y, Ikegawa S, Cloning and characterization of the osteoarthritis-associated gene DVWA. J Bone Miner Metab. 2011 May;29(3):300-8 |
Col7a1 collagen, type VII, alpha 1 | |
Results | Reference |
1* | J:117883 Chiotaki R, Petrou P, Giakoumaki E, Pavlakis E, Sitaru C, Chalepakis G, Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development. Gene Expr Patterns. 2007 Feb;7(4):381-8 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Col8a1 collagen, type VIII, alpha 1 (Synonyms: Col8a-1) | |
Results | Reference |
2* | J:35224 Iruela-Arispe ML, Sage EH, Expression of type VIII collagen during morphogenesis of the chicken and mouse heart. Dev Biol. 1991 Mar;144(1):107-18 |
Col8a2 collagen, type VIII, alpha 2 | |
Results | Reference |
2* | J:35224 Iruela-Arispe ML, Sage EH, Expression of type VIII collagen during morphogenesis of the chicken and mouse heart. Dev Biol. 1991 Mar;144(1):107-18 |
Col9a1 collagen, type IX, alpha 1 (Synonyms: Col9a-1) | |
Results | Reference |
1 | J:194035 Kan A, Tabin CJ, c-Jun is required for the specification of joint cell fates. Genes Dev. 2013 Mar 1;27(5):514-24 |
2 | J:16153 Liu CY, Olsen BR, Kao WW, Developmental patterns of two alpha 1(IX) collagen mRNA isoforms in mouse. Dev Dyn. 1993 Oct;198(2):150-7 |
1 | J:193853 Makino Y, Takahashi Y, Tanabe R, Tamamura Y, Watanabe T, Haraikawa M, Hamagaki M, Hata K, Kanno J, Yoneda T, Saga Y, Goseki-Sone M, Kaneko K, Yamaguchi A, Iimura T, Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone. 2013 Mar;53(1):248-58 |
2 | J:40590 Perala M, Savontaus M, Metsaranta M, Vuorio E, Developmental regulation of mRNA species for types II, IX and XI collagens during mouse embryogenesis. Biochem J. 1997 May 15;324(Pt 1):209-16 |
1* | J:84724 Rahkonen O, Savontaus M, Abdelwahid E, Vuorio E, Jokinen E, Expression patterns of cartilage collagens and Sox9 during mouse heart development. Histochem Cell Biol. 2003 Aug;120(2):103-10 |
1* | J:44842 Savontaus M, Metsaranta M, Vuorio E, Mutation in type II collagen gene disturbs spinal development and gene expression patterns in transgenic Del1 mice. Lab Invest. 1997 Dec;77(6):591-600 |
1* | J:37148 Savontaus M, Metsranta M, Vuorio E, Retarded skeletal development in transgenic mice with a type II collagen mutation. Am J Pathol. 1996 Dec;149(6):2169-82 |
1 | J:95068 Savontaus M, Rintala-Jamsa M, Morko J, Ronning O, Metsaranta M, Vuorio E, Abnormal craniofacial development and expression patterns of extracellular matrix components in transgenic Del1 mice harboring a deletion mutation in the type II collagen gene. Orthod Craniofac Res. 2004 Nov;7(4):216-26 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1 | J:48562 Wai AW, Ng LJ, Watanabe H, Yamada Y, Tam PP, Cheah KS, Disrupted expression of matrix genes in the growth plate of the mouse cartilage matrix deficiency (cmd) mutant. Dev Genet. 1998;22(4):349-58 |
Col9a2 collagen, type IX, alpha 2 (Synonyms: Col9a-2) | |
Results | Reference |
2 | J:40590 Perala M, Savontaus M, Metsaranta M, Vuorio E, Developmental regulation of mRNA species for types II, IX and XI collagens during mouse embryogenesis. Biochem J. 1997 May 15;324(Pt 1):209-16 |
1* | J:84724 Rahkonen O, Savontaus M, Abdelwahid E, Vuorio E, Jokinen E, Expression patterns of cartilage collagens and Sox9 during mouse heart development. Histochem Cell Biol. 2003 Aug;120(2):103-10 |
1 | J:302296 Vong KI, Ma TC, Li B, Leung TCN, Nong W, Ngai SM, Hui JHL, Jiang L, Kwan KM, SOX9-COL9A3-dependent regulation of choroid plexus epithelial polarity governs blood-cerebrospinal fluid barrier integrity. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2009568118 |
Col9a3 collagen, type IX, alpha 3 | |
Results | Reference |
2 | J:40590 Perala M, Savontaus M, Metsaranta M, Vuorio E, Developmental regulation of mRNA species for types II, IX and XI collagens during mouse embryogenesis. Biochem J. 1997 May 15;324(Pt 1):209-16 |
1 | J:67267 Perera EM, Martin H, Seeherunvong T, Kos L, Hughes IA, Hawkins JR, Berkovitz GD, Tescalcin, a novel gene encoding a putative EF-hand Ca(2+)-binding protein, Col9a3, and renin are expressed in the mouse testis during the early stages of gonadal differentiation. Endocrinology. 2001 Jan;142(1):455-63 |
1* | J:84724 Rahkonen O, Savontaus M, Abdelwahid E, Vuorio E, Jokinen E, Expression patterns of cartilage collagens and Sox9 during mouse heart development. Histochem Cell Biol. 2003 Aug;120(2):103-10 |
1 | J:302296 Vong KI, Ma TC, Li B, Leung TCN, Nong W, Ngai SM, Hui JHL, Jiang L, Kwan KM, SOX9-COL9A3-dependent regulation of choroid plexus epithelial polarity governs blood-cerebrospinal fluid barrier integrity. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2009568118 |
Col10a1 collagen, type X, alpha 1 (Synonyms: Col10, Col10a-1) | |
Results | Reference |
1 | J:90567 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 2004 May 1;18(9):1072-87 |
1* | J:75699 Albrecht AN, Schwabe GC, Stricker S, Boddrich A, Wanker EE, Mundlos S, The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67 |
2 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
1 | J:67299 Arikawa-Hirasawa E, Watanabe H, Takami H, Hassell JR, Yamada Y, Perlecan is essential for cartilage and cephalic development. Nat Genet. 1999 Nov;23(3):354-8 |
1 | J:119152 Arnold MA, Kim Y, Czubryt MP, Phan D, McAnally J, Qi X, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN, MEF2C transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell. 2007 Mar;12(3):377-89 |
1 | J:337598 Au TYK, Yip RKH, Wynn SL, Tan TY, Fu A, Geng YH, Szeto IYY, Niu B, Yip KY, Cheung MCH, Lovell-Badge R, Cheah KSE, Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog-Wnt signaling, causing campomelia. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2208623119 |
1 | J:155396 Bellon E, Luyten FP, Tylzanowski P, delta-EF1 is a negative regulator of Ihh in the developing growth plate. J Cell Biol. 2009 Nov 30;187(5):685-99 |
1* | J:85724 Bendall AJ, Hu G, Levi G, Abate-Shen C, Dlx5 regulates chondrocyte differentiation at multiple stages. Int J Dev Biol. 2003 Jun;47(5):335-44 |
1 | J:196913 Bertrand J, Stange R, Hidding H, Echtermeyer F, Nalesso G, Godmann L, Timmen M, Bruckner P, Dell'Accio F, Raschke MJ, Pap T, Dreier R, Syndecan 4 supports bone fracture repair, but not fetal skeletal development, in mice. Arthritis Rheum. 2013 Mar;65(3):743-52 |
1* | J:168038 Bimonte S, De Angelis A, Quagliata L, Giusti F, Tammaro R, Dallai R, Ascenzi MG, Diez-Roux G, Franco B, Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol. 2011 Jan 15;349(2):179-91 |
1* | J:237308 Biosse Duplan M, Komla-Ebri D, Heuze Y, Estibals V, Gaudas E, Kaci N, Benoist-Lasselin C, Zerah M, Kramer I, Kneissel M, Porta DG, Di Rocco F, Legeai-Mallet L, Meckel's and condylar cartilages anomalies in achondroplasia result in defective development and growth of the mandible. Hum Mol Genet. 2016 Jul 15;25(14):2997-3010 |
1 | J:156015 Blitz E, Viukov S, Sharir A, Shwartz Y, Galloway JL, Pryce BA, Johnson RL, Tabin CJ, Schweitzer R, Zelzer E, Bone ridge patterning during musculoskeletal assembly is mediated through SCX regulation of Bmp4 at the tendon-skeleton junction. Dev Cell. 2009 Dec;17(6):861-73 |
1 | J:90403 Boulet AM, Capecchi MR, Multiple roles of Hoxa11 and Hoxd11 in the formation of the mammalian forelimb zeugopod. Development. 2004 Jan;131(2):299-309 |
1* | J:248190 Chen K, Quan H, Chen G, Xiao D, Spatio-temporal expression patterns of Wnt signaling pathway during the development of temporomandibular condylar cartilage. Gene Expr Patterns. 2017 Nov;25-26:149-158 |
2* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:232617 Chen Z, Yue SX, Zhou G, Greenfield EM, Murakami S, ERK1 and ERK2 regulate chondrocyte terminal differentiation during endochondral bone formation. J Bone Miner Res. 2015 May;30(5):765-74 |
1 | J:327334 Choi KY, Lee SW, Park MH, Bae YC, Shin HI, Nam S, Kim YJ, Kim HJ, Ryoo HM, Spatio-temporal expression patterns of Runx2 isoforms in early skeletogenesis. Exp Mol Med. 2002 Dec 31;34(6):426-33 |
1 | J:107668 Cobb J, Dierich A, Huss-Garcia Y, Duboule D, A mouse model for human short-stature syndromes identifies Shox2 as an upstream regulator of Runx2 during long-bone development. Proc Natl Acad Sci U S A. 2006 Mar 21;103(12):4511-5 |
1* | J:66902 Colnot C, Sidhu SS, Balmain N, Poirier F, Uncoupling of chondrocyte death and vascular invasion in mouse galectin 3 null mutant bones. Dev Biol. 2001 Jan 1;229(1):203-14 |
1* | J:89221 Dacquin R, Mee PJ, Kawaguchi J, Olmsted-Davis EA, Gallagher JA, Nichols J, Lee K, Karsenty G, Smith A, Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar. Dev Dyn. 2004 Apr;229(4):826-34 |
1 | J:210100 Di Rocco F, Biosse Duplan M, Heuze Y, Kaci N, Komla-Ebri D, Munnich A, Mugniery E, Benoist-Lasselin C, Legeai-Mallet L, FGFR3 mutation causes abnormal membranous ossification in achondroplasia. Hum Mol Genet. 2014 Jun 1;23(11):2914-25 |
1 | J:230611 Dierker T, Bachvarova V, Krause Y, Li JP, Kjellen L, Seidler DG, Vortkamp A, Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones. Matrix Biol. 2016 Jan;49:82-92 |
1 | J:317276 Dittmann K, Wuelling M, Uhmann A, Dullin C, Hahn H, Schweyer S, Vortkamp A, Wienands J, Inactivation of patched1 in murine chondrocytes causes spinal fusion without inflammation. Arthritis Rheumatol. 2014 Apr;66(4):831-40 |
1* | J:195901 Ehlen H, Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues. J Bone Miner Res. 2013;28(2):246-59 |
2 | J:202337 Estrada KD, Wang W, Retting KN, Chien CT, Elkhoury FF, Heuchel R, Lyons KM, Smad7 regulates terminal maturation of chondrocytes in the growth plate. Dev Biol. 2013 Oct 15;382(2):375-84 |
1* | J:26819 Gack S, Vallon R, Schmidt J, Grigoriadis A, Tuckermann J, Schenkel J, Weiher H, Wagner EF, Angel P, Expression of interstitial collagenase during skeletal development of the mouse is restricted to osteoblast-like cells and hypertrophic chondrocytes. Cell Growth Differ. 1995 Jun;6(6):759-67 |
1 | J:151466 Gamer LW, Cox K, Carlo JM, Rosen V, Overexpression of BMP3 in the developing skeleton alters endochondral bone formation resulting in spontaneous rib fractures. Dev Dyn. 2009 Aug 3;238(9):2374-2381 |
1 | J:111426 Ganss B, Kobayashi H, The zinc finger transcription factor Zfp60 is a negative regulator of cartilage differentiation. J Bone Miner Res. 2002 Dec;17(12):2151-60 |
1* | J:138379 Gu S, Wei N, Yu L, Fei J, Chen Y, Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice. Mech Dev. 2008 Aug;125(8):729-42 |
1 | J:150187 Guo X, Mak KK, Taketo MM, Yang Y, The Wnt/beta-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturation. PLoS One. 2009;4(6):e6067 |
1 | J:159025 Hattori T, Muller C, Gebhard S, Bauer E, Pausch F, Schlund B, Bosl MR, Hess A, Surmann-Schmitt C, von der Mark H, de Crombrugghe B, von der Mark K, SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification. Development. 2010 Mar;137(6):901-11 |
1* | J:163483 He G, Tavella S, Hanley KP, Self M, Oliver G, Grifone R, Hanley N, Ward C, Bobola N, Inactivation of Six2 in mouse identifies a novel genetic mechanism controlling development and growth of the cranial base. Dev Biol. 2010 Aug 15;344(2):720-30 |
1 | J:236411 He X, Ohba S, Hojo H, McMahon AP, AP-1 family members act with Sox9 to promote chondrocyte hypertrophy. Development. 2016 Aug 15;143(16):3012-23 |
1 | J:104933 Hilton MJ, Gutierrez L, Martinez DA, Wells DE, EXT1 regulates chondrocyte proliferation and differentiation during endochondral bone development. Bone. 2005 Mar;36(3):379-86 |
1 | J:114686 Hinoi E, Bialek P, Chen YT, Rached MT, Groner Y, Behringer RR, Ornitz DM, Karsenty G, Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes Dev. 2006 Nov 1;20(21):2937-42 |
1 | J:146280 Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H, C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57. PLoS One. 2009;4(2):e4543 |
1 | J:237341 Houben A, Kostanova-Poliakova D, Weissenbock M, Graf J, Teufel S, von der Mark K, Hartmann C, beta-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis. Development. 2016 Oct 15;143(20):3826-3838 |
2 | J:175769 Hsu SH, Zhang X, Yu C, Li ZJ, Wunder JS, Hui CC, Alman BA, Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu. Development. 2011 Sep;138(17):3791-801 |
1 | J:94274 Hu H, Hilton MJ, Tu X, Yu K, Ornitz DM, Long F, Sequential roles of Hedgehog and Wnt signaling in osteoblast development. Development. 2005 Jan;132(1):49-60 |
1 | J:231474 Hung IH, Schoenwolf GC, Lewandoski M, Ornitz DM, A combined series of Fgf9 and Fgf18 mutant alleles identifies unique and redundant roles in skeletal development. Dev Biol. 2016 Mar 1;411(1):72-84 |
1 | J:109399 Ichikawa Y, Sumi M, Ohwatari N, Komori T, Sumi T, Shibata H, Furuichi T, Yamaguchi A, Nakamura T, Evaluation of 9.4-T MR microimaging in assessing normal and defective fetal bone development: comparison of MR imaging and histological findings. Bone. 2004 Apr;34(4):619-28 |
2* | J:194983 Ideno H, Shimada A, Imaizumi K, Kimura H, Abe M, Nakashima K, Nifuji A, Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development. Gene Expr Patterns. 2013 Mar-Apr;13(3-4):84-90 |
1* | J:103991 Ijiri K, Zerbini LF, Peng H, Correa RG, Lu B, Walsh N, Zhao Y, Taniguchi N, Huang XL, Otu H, Wang H, Wang JF, Komiya S, Ducy P, Rahman MU, Flavell RA, Gravallese EM, Oettgen P, Libermann TA, Goldring MB, A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation. J Biol Chem. 2005 Nov 18;280(46):38544-55 |
1 | J:188132 Ikeda K, Tsukui T, Imazawa Y, Horie-Inoue K, Inoue S, Conditional expression of constitutively active estrogen receptor alpha in chondrocytes impairs longitudinal bone growth in mice. Biochem Biophys Res Commun. 2012 Sep 7;425(4):912-7 |
1 | J:153633 Ito T, Yadav N, Lee J, Furumatsu T, Yamashita S, Yoshida K, Taniguchi N, Hashimoto M, Tsuchiya M, Ozaki T, Lotz M, Bedford MT, Asahara H, Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC Dev Biol. 2009;9:47 |
1 | J:83260 Ivkovic S, Yoon BS, Popoff SN, Safadi FF, Libuda DE, Stephenson RC, Daluiski A, Lyons KM, Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development. Development. 2003 Jun;130(12):2779-91 |
1 | J:119288 Jacob AL, Smith C, Partanen J, Ornitz DM, Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation. Dev Biol. 2006 Aug 15;296(2):315-28 |
1 | J:233766 Jiang Q, Qin X, Kawane T, Komori H, Matsuo Y, Taniuchi I, Ito K, Izumi S, Komori T, Cbfb2 Isoform Dominates More Potent Cbfb1 and Is Required for Skeletal Development. J Bone Miner Res. 2016 Jul;31(7):1391-404 |
1* | J:300574 Jiang Q, Qin X, Yoshida CA, Komori H, Yamana K, Ohba S, Hojo H, Croix BS, Kawata-Matsuura VKS, Komori T, Antxr1, Which is a Target of Runx2, Regulates Chondrocyte Proliferation and Apoptosis. Int J Mol Sci. 2020 Mar 31;21(7):2425 |
1 | J:94393 Karreth F, Hoebertz A, Scheuch H, Eferl R, Wagner EF, The AP1 transcription factor Fra2 is required for efficient cartilage development. Development. 2004 Nov;131(22):5717-25 |
2 | J:155442 Kawaki H, Kubota S, Suzuki A, Lazar N, Yamada T, Matsumura T, Ohgawara T, Maeda T, Perbal B, Lyons KM, Takigawa M, Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage. J Bone Miner Res. 2008 Nov;23(11):1751-64 |
1* | J:160585 Kesper DA, Didt-Koziel L, Vortkamp A, Gli2 activator function in preosteoblasts is sufficient to mediate Ihh-dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification. Dev Dyn. 2010 Jun;239(6):1818-26 |
1 | J:143940 Kimura H, Kwan KM, Zhang Z, Deng JM, Darnay BG, Behringer RR, Nakamura T, de Crombrugghe B, Akiyama H, Cthrc1 is a positive regulator of osteoblastic bone formation. PLoS One. 2008;3(9):e3174 |
1* | J:158147 Kinoshita M, Era T, Jakt LM, Nishikawa S, The novel protein kinase Vlk is essential for stromal function of mesenchymal cells. Development. 2009 Jun;136(12):2069-79 |
1 | J:92212 Koziel L, Kunath M, Kelly OG, Vortkamp A, Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification. Dev Cell. 2004 Jun;6(6):801-13 |
1 | J:102948 Koziel L, Wuelling M, Schneider S, Vortkamp A, Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation. Development. 2005 Dec;132(23):5249-60 |
1 | J:102448 Kugimiya F, Kawaguchi H, Kamekura S, Chikuda H, Ohba S, Yano F, Ogata N, Katagiri T, Harada Y, Azuma Y, Nakamura K, Chung UI, Involvement of endogenous bone morphogenetic protein (BMP) 2 and BMP6 in bone formation. J Biol Chem. 2005 Oct 21;280(42):35704-12 |
1* | J:81315 Kunath M, Ludecke HJ, Vortkamp A, Expression of Trps1 during mouse embryonic development. Mech Dev. 2002 Dec;119 Suppl 1:S117-20 |
1 | J:80669 Kundu M, Javed A, Jeon JP, Horner A, Shum L, Eckhaus M, Muenke M, Lian JB, Yang Y, Nuckolls GH, Stein GS, Liu PP, Cbfbeta interacts with Runx2 and has a critical role in bone development. Nat Genet. 2002 Dec;32(4):639-44 |
1* | J:56909 Lanske B, Amling M, Neff L, Guiducci J, Baron R, Kronenberg HM, Ablation of the PTHrP gene or the PTH/PTHrP receptor gene leads to distinct abnormalities in bone development. J Clin Invest. 1999 Aug;104(4):399-407 |
1* | J:331874 Lee H, Kim DW, Deletion of ATAD3A inhibits osteogenesis by impairing mitochondria structure and function in pre-osteoblast. Dev Dyn. 2022 Dec;251(12):1982-2000 |
1* | J:60156 Lee K, Lanske B, Karaplis AC, Deeds JD, Kohno H, Nissenson RA, Kronenberg HM, Segre GV, Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development. Endocrinology. 1996 Nov;137(11):5109-18 |
1 | J:268341 Lee SY, Abel ED, Long F, Glucose metabolism induced by Bmp signaling is essential for murine skeletal development. Nat Commun. 2018 Nov 16;9(1):4831 |
1 | J:316483 Leek CC, Soulas JM, Bhattacharya I, Ganji E, Locke RC, Smith MC, Bhavsar JD, Polson SW, Ornitz DM, Killian ML, Deletion of Fibroblast growth factor 9 globally and in skeletal muscle results in enlarged tuberosities at sites of deltoid tendon attachments. Dev Dyn. 2021 Dec;250(12):1778-1795 |
1 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
1* | J:236167 Li J, Manickam G, Ray S, Oh CD, Yasuda H, Moffatt P, Murshed M, Smpd3 Expression in both Chondrocytes and Osteoblasts Is Required for Normal Endochondral Bone Development. Mol Cell Biol. 2016 Sep 1;36(17):2282-99 |
1* | J:355649 Li Q, Jiang S, Lei K, Han H, Chen Y, Lin W, Xiong Q, Qi X, Gan X, Sheng R, Wang Y, Zhang Y, Ma J, Li T, Lin S, Zhou C, Chen D, Yuan Q, Metabolic rewiring during bone development underlies tRNA m7G-associated primordial dwarfism. J Clin Invest. 2024 Sep 10;134(20) |
1 | J:88635 Long F, Chung UI, Ohba S, McMahon J, Kronenberg HM, McMahon AP, Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development. 2004 Mar;131(6):1309-18 |
1* | J:67153 Long F, Schipani E, Asahara H, Kronenberg H, Montminy M, The CREB family of activators is required for endochondral bone development. Development. 2001 Feb;128(4):541-50 |
1 | J:125095 Lu J, Lian G, Lenkinski R, De Grand A, Vaid RR, Bryce T, Stasenko M, Boskey A, Walsh C, Sheen V, Filamin B mutations cause chondrocyte defects in skeletal development. Hum Mol Genet. 2007 Jul 15;16(14):1661-75 |
1 | J:152843 Luo J, Zhou W, Zhou X, Li D, Weng J, Yi Z, Cho SG, Li C, Yi T, Wu X, Li XY, de Crombrugghe B, Hook M, Liu M, Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development. 2009 Aug;136(16):2747-56 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1* | J:85738 MacLean HE, Kim JI, Glimcher MJ, Wang J, Kronenberg HM, Glimcher LH, Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development. Dev Biol. 2003 Oct 1;262(1):51-63 |
1* | J:93152 Maclean HE, Kronenberg HM, Expression of Stra13 during mouse endochondral bone development. Gene Expr Patterns. 2004 Oct;4(6):633-6 |
1 | J:233282 Maes C, Araldi E, Haigh K, Khatri R, Van Looveren R, Giaccia AJ, Haigh JJ, Carmeliet G, Schipani E, VEGF-independent cell-autonomous functions of HIF-1alpha regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival. J Bone Miner Res. 2012 Mar;27(3):596-609 |
1 | J:193853 Makino Y, Takahashi Y, Tanabe R, Tamamura Y, Watanabe T, Haraikawa M, Hamagaki M, Hata K, Kanno J, Yoneda T, Saga Y, Goseki-Sone M, Kaneko K, Yamaguchi A, Iimura T, Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone. 2013 Mar;53(1):248-58 |
1 | J:152912 Matsumoto K, Li Y, Jakuba C, Sugiyama Y, Sayo T, Okuno M, Dealy CN, Toole BP, Takeda J, Yamaguchi Y, Kosher RA, Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb. Development. 2009 Aug;136(16):2825-35 |
1 | J:296737 Matsuura VKSK, Yoshida CA, Komori H, Sakane C, Yamana K, Jiang Q, Komori T, Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice. Int J Mol Sci. 2020 Apr 12;21(8):2682 |
1 | J:121301 Mau E, Whetstone H, Yu C, Hopyan S, Wunder JS, Alman BA, PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms. Dev Biol. 2007 May 1;305(1):28-39 |
1 | J:149225 Miclea RL, Karperien M, Bosch CA, van der Horst G, van der Valk MA, Kobayashi T, Kronenberg HM, Rawadi G, Akcakaya P, Lowik CW, Fodde R, Wit JM, Robanus-Maandag EC, Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors. BMC Dev Biol. 2009;9:26 |
1 | J:205339 Mis EK, Liem KF Jr, Kong Y, Schwartz NB, Domowicz M, Weatherbee SD, Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length. Dev Biol. 2014 Jan 1;385(1):67-82 |
1 | J:318774 Monemdjou R, Vasheghani F, Fahmi H, Perez G, Blati M, Taniguchi N, Lotz M, St-Arnaud R, Pelletier JP, Martel-Pelletier J, Beier F, Kapoor M, Association of cartilage-specific deletion of peroxisome proliferator-activated receptor gamma with abnormal endochondral ossification and impaired cartilage growth and development in a murine model. Arthritis Rheum. 2012 May;64(5):1551-61 |
1 | J:170582 Mundy C, Yasuda T, Kinumatsu T, Yamaguchi Y, Iwamoto M, Enomoto-Iwamoto M, Koyama E, Pacifici M, Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine. Dev Biol. 2011 Mar 1;351(1):70-81 |
1 | J:316165 Nakamura E, Hata K, Takahata Y, Kurosaka H, Abe M, Abe T, Kihara M, Komori T, Kobayashi S, Murakami T, Inubushi T, Yamashiro T, Yamamoto S, Akiyama H, Kawaguchi M, Sakata N, Nishimura R, Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice. Commun Biol. 2021 Nov 3;4(1):1258 |
1* | J:74344 Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B, The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 2002 Jan 11;108(1):17-29 |
1 | J:136877 Napierala D, Sam K, Morello R, Zheng Q, Munivez E, Shivdasani RA, Lee B, Uncoupling of chondrocyte differentiation and perichondrial mineralization underlies the skeletal dysplasia in tricho-rhino-phalangeal syndrome. Hum Mol Genet. 2008 Jul 15;17(14):2244-54 |
1* | J:317046 Niebler S, Schubert T, Hunziker EB, Bosserhoff AK, Activating enhancer binding protein 2 epsilon (AP-2epsilon)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development. Arthritis Res Ther. 2015 May 12;17:119 |
1 | J:316655 Oh SK, Shin JO, Baek JI, Lee J, Bae JW, Ankamerddy H, Kim MJ, Huh TL, Ryoo ZY, Kim UK, Bok J, Lee KY, Pannexin 3 is required for normal progression of skeletal development in vertebrates. FASEB J. 2015 Nov;29(11):4473-84 |
2 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1* | J:265842 Palagano E, Zuccarini G, Prontera P, Borgatti R, Stangoni G, Elisei S, Mantero S, Menale C, Forlino A, Uva P, Oppo M, Vezzoni P, Villa A, Merlo GR, Sobacchi C, Mutations in the Neuroblastoma Amplified Sequence gene in a family affected by Acrofrontofacionasal Dysostosis type 1. Bone. 2018 Sep;114:125-136 |
1 | J:258274 Patra D, DeLassus E, Mueller J, Abou-Ezzi G, Sandell LJ, Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice. Biol Open. 2018 Feb 22;7(2):bio032094 |
1 | J:40590 Perala M, Savontaus M, Metsaranta M, Vuorio E, Developmental regulation of mRNA species for types II, IX and XI collagens during mouse embryogenesis. Biochem J. 1997 May 15;324(Pt 1):209-16 |
1* | J:254498 Poulet B, Liu K, Plumb D, Vo P, Shah M, Staines K, Sampson A, Nakamura H, Nagase H, Carriero A, Shefelbine S, Pitsillides AA, Bou-Gharios G, Overexpression of TIMP-3 in Chondrocytes Produces Transient Reduction in Growth Plate Length but Permanently Reduces Adult Bone Quality and Quantity. PLoS One. 2016;11(12):e0167971 |
1* | J:199462 Probst S, Zeller R, Zuniga A, The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development. Differentiation. 2013 Apr-Jun;85(4-5):121-30 |
1 | J:128917 Provot S, Nachtrab G, Paruch J, Chen AP, Silva A, Kronenberg HM, A-raf and B-raf are dispensable for normal endochondral bone development, and parathyroid hormone-related peptide suppresses extracellular signal-regulated kinase activation in hypertrophic chondrocytes. Mol Cell Biol. 2008 Jan;28(1):344-57 |
1* | J:356701 Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD, Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr;91(4):387-93 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1 | J:219841 Qin X, Jiang Q, Matsuo Y, Kawane T, Komori H, Moriishi T, Taniuchi I, Ito K, Kawai Y, Rokutanda S, Izumi S, Komori T, Cbfb regulates bone development by stabilizing runx family proteins. J Bone Miner Res. 2015 Apr;30(4):706-14 |
1 | J:299239 Qin X, Jiang Q, Nagano K, Moriishi T, Miyazaki T, Komori H, Ito K, Mark KV, Sakane C, Kaneko H, Komori T, Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts. PLoS Genet. 2020 Nov;16(11):e1009169 |
1* | J:130163 Ratzka A, Kalus I, Moser M, Dierks T, Mundlos S, Vortkamp A, Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development. Dev Dyn. 2008 Feb;237(2):339-53 |
1 | J:102870 Razzaque MS, Soegiarto DW, Chang D, Long F, Lanske B, Conditional deletion of Indian hedgehog from collagen type 2alpha1-expressing cells results in abnormal endochondral bone formation. J Pathol. 2005 Dec;207(4):453-61 |
1 | J:76480 Robledo RF, Rajan L, Li X, Lufkin T, The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev. 2002 May 1;16(9):1089-101 |
1 | J:124105 Ruiz-Perez VL, Blair HJ, Rodriguez-Andres ME, Blanco MJ, Wilson A, Liu YN, Miles C, Peters H, Goodship JA, Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. Development. 2007 Aug;134(16):2903-12 |
1 | J:142447 Sato S, Kimura A, Ozdemir J, Asou Y, Miyazaki M, Jinno T, Ae K, Liu X, Osaki M, Takeuchi Y, Fukumoto S, Kawaguchi H, Haro H, Shinomiya K, Karsenty G, Takeda S, The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration: Findings in murine models and in human disease. Arthritis Rheum. 2008 Sep;58(9):2764-75 |
1* | J:37148 Savontaus M, Metsranta M, Vuorio E, Retarded skeletal development in transgenic mice with a type II collagen mutation. Am J Pathol. 1996 Dec;149(6):2169-82 |
2 | J:95068 Savontaus M, Rintala-Jamsa M, Morko J, Ronning O, Metsaranta M, Vuorio E, Abnormal craniofacial development and expression patterns of extracellular matrix components in transgenic Del1 mice harboring a deletion mutation in the type II collagen gene. Orthod Craniofac Res. 2004 Nov;7(4):216-26 |
1* | J:207837 Schmid R, Bosserhoff AK, Redundancy in regulation of chondrogenesis in MIA/CD-RAP-deficient mice. Mech Dev. 2014 Feb;131:24-34 |
1 | J:279005 Schroeder N, Wuelling M, Hoffmann D, Brand-Saberi B, Vortkamp A, Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bones. PLoS One. 2019;14(8):e0218230 |
1* | J:143455 Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Al Awqati Q, Ballabio A, Karsenty G, Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification. Genes Dev. 2008 Oct 1;22(19):2645-50 |
2* | J:76140 Shibata S, Fukada K, Suzuki S, Ogawa T, Yamashita Y, In situ hybridization and immunohistochemistry of bone sialoprotein and secreted phosphoprotein 1 (osteopontin) in the developing mouse mandibular condylar cartilage compared with limb bud cartilage. J Anat. 2002 Mar;200(Pt 3):309-20 |
1* | J:45403 Shibata S, Fukada K, Suzuki S, Yamashita Y, Immunohistochemistry of collagen types II and X, and enzyme-histochemistry of alkaline phosphatase in the developing condylar cartilage of the fetal mouse mandible. J Anat. 1997 Nov;191(Pt 4):561-70 |
1 | J:150837 Shim JH, Greenblatt MB, Xie M, Schneider MD, Zou W, Zhai B, Gygi S, Glimcher LH, TAK1 is an essential regulator of BMP signalling in cartilage. EMBO J. 2009 Jul 22;28(14):2028-41 |
1 | J:141868 Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H, Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9. J Biol Chem. 2008 Sep 5;283(36):24682-9 |
2 | J:95959 Smith N, Dong Y, Lian JB, Pratap J, Kingsley PD, van Wijnen AJ, Stein JL, Schwarz EM, O'keefe RJ, Stein GS, Drissi MH, Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. J Cell Physiol. 2005 Apr;203(1):133-43 |
1* | J:80666 Smits P, Li P, Mandel J, Zhang Z, Deng JM, Behringer RR, de Croumbrugghe B, Lefebvre V, The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001 Aug;1(2):277-90 |
1 | J:134924 Spagnoli A, O'Rear L, Chandler RL, Granero-Molto F, Mortlock DP, Gorska AE, Weis JA, Longobardi L, Chytil A, Shimer K, Moses HL, TGF-beta signaling is essential for joint morphogenesis. J Cell Biol. 2007 Jun 18;177(6):1105-17 |
1* | J:57297 St-Jacques B, Hammerschmidt M, McMahon AP, Indian hedgehog signaling regulates proliferation and differentiation of chondrocytes and is essential for bone formation [published erratum appears in Genes Dev 1999 Oct 1;13(19):2617]. Genes Dev. 1999 Aug 15;13(16):2072-86 |
1 | J:191584 Sueyoshi T, Yamamoto K, Akiyama H, Conditional deletion of Tgfbr2 in hypertrophic chondrocytes delays terminal chondrocyte differentiation. Matrix Biol. 2012 Jul;31(6):352-9 |
1* | J:67784 Takeda S, Bonnamy JP, Owen MJ, Ducy P, Karsenty G, Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. Genes Dev. 2001 Feb 15;15(4):467-81 |
1* | J:62593 Tanaka K, Matsumoto Y, Nakatani F, Iwamoto Y, Yamada Y, A zinc finger transcription factor, alphaA-crystallin binding protein 1, is a negative regulator of the chondrocyte-specific enhancer of the alpha1(II) collagen gene. (Retraction and replacement of Figures 1D and 7 appear in 2006; 26(13):5202). Mol Cell Biol. 2000 Jun;20(12):4428-35 |
1 | J:84273 Terpstra L, Prud'homme J, Arabian A, Takeda S, Karsenty G, Dedhar S, St-Arnaud R, Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes. J Cell Biol. 2003 Jul 7;162(1):139-48 |
1 | J:326699 Tosun B, Wolff LI, Houben A, Nutt S, Hartmann C, Osteoclasts and Macrophages-Their Role in Bone Marrow Cavity Formation During Mouse Embryonic Development. J Bone Miner Res. 2022 Jun 11; |
1 | J:112372 Tsumaki N, Nakase T, Miyaji T, Kakiuchi M, Kimura T, Ochi T, Yoshikawa H, Bone morphogenetic protein signals are required for cartilage formation and differently regulate joint development during skeletogenesis. J Bone Miner Res. 2002 May;17(5):898-906 |
1 | J:52419 Tsumaki N, Tanaka K, Arikawa-Hirasawa E, Nakase T, Kimura T, Thomas JT, Ochi T, Luyten FP, Yamada Y, Role of CDMP-1 in skeletal morphogenesis: promotion of mesenchymal cell recruitment and chondrocyte differentiation. J Cell Biol. 1999 Jan 11;144(1):161-73 |
2 | J:264124 Tsushima H, Tang YJ, Puviindran V, Hsu SC, Nadesan P, Yu C, Zhang H, Mirando AJ, Hilton MJ, Alman BA, Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis. Development. 2018 Jul 9;145(13):dev162396 |
1* | J:209518 Ushijima T, Okazaki K, Tsushima H, Iwamoto Y, CCAAT/enhancer-binding protein beta regulates the repression of type II collagen expression during the differentiation from proliferative to hypertrophic chondrocytes. J Biol Chem. 2014 Jan 31;289(5):2852-63 |
1 | J:112002 van der Weyden L, Wei L, Luo J, Yang X, Birk DE, Adams DJ, Bradley A, Chen Q, Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis. Am J Pathol. 2006 Aug;169(2):515-27 |
1* | J:104555 Viviano BL, Silverstein L, Pflederer C, Paine-Saunders S, Mills K, Saunders S, Altered hematopoiesis in glypican-3-deficient mice results in decreased osteoclast differentiation and a delay in endochondral ossification. Dev Biol. 2005 Jun 1;282(1):152-62 |
1 | J:122563 Wang G, Woods A, Agoston H, Ulici V, Glogauer M, Beier F, Genetic ablation of Rac1 in cartilage results in chondrodysplasia. Dev Biol. 2007 Jun 15;306(2):612-23 |
1* | J:154906 Wang W, Lian N, Li L, Moss HE, Wang W, Perrien DS, Elefteriou F, Yang X, Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription. Development. 2009 Dec;136(24):4143-53 |
1 | J:177115 Wang Y, Liu C, Rohr J, Liu H, He F, Yu J, Sun C, Li L, Gu S, Chen Y, Tissue interaction is required for glenoid fossa development during temporomandibular joint formation. Dev Dyn. 2011 Nov;240(11):2466-73 |
1* | J:200760 Wang Y, Zheng Y, Chen D, Chen Y, Enhanced BMP signaling prevents degeneration and leads to endochondral ossification of Meckel's cartilage in mice. Dev Biol. 2013 Sep 15;381(2):301-11 |
1* | J:195062 Watanabe T, Oyama T, Asada M, Harada D, Ito Y, Inagawa M, Suzuki Y, Sugano S, Katsube K, Karsenty G, Komori T, Kitagawa M, Asahara H, MAML1 enhances the transcriptional activity of Runx2 and plays a role in bone development. PLoS Genet. 2013 Jan;9(1):e1003132 |
1 | J:236410 Watson EC, Koenig MN, Grant ZL, Whitehead L, Trounson E, Dewson G, Coultas L, Apoptosis regulates endothelial cell number and capillary vessel diameter but not vessel regression during retinal angiogenesis. Development. 2016 Aug 15;143(16):2973-82 |
1 | J:172737 Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RA, Peterson AS, Solloway MJ, Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol. 2011 May 30;193(5):935-51 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1* | J:307192 Yadav PS, Feng S, Cong Q, Kim H, Liu Y, Yang Y, Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118 |
1 | J:102996 Yamaai T, Nakanishi T, Asano M, Nawachi K, Yoshimichi G, Ohyama K, Komori T, Sugimoto T, Takigawa M, Gene expression of connective tissue growth factor (CTGF/CCN2) in calcifying tissues of normal and cbfa1-null mutant mice in late stage of embryonic development. J Bone Miner Metab. 2005;23(4):280-8 |
1 | J:320311 Yang L, Gu S, Ye W, Song Y, Chen Y, Augmented Indian hedgehog signaling in cranial neural crest cells leads to craniofacial abnormalities and dysplastic temporomandibular joint in mice. Cell Tissue Res. 2016 Apr;364(1):105-15 |
2* | J:213921 Yang L, Tsang KY, Tang HC, Chan D, Cheah KS, Hypertrophic chondrocytes can become osteoblasts and osteocytes in endochondral bone formation. Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):12097-102 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
1 | J:360708 Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K, Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase. Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2320070121 |
1 | J:233350 Zhang F, Xu L, Xu L, Xu Q, Li D, Yang Y, Karsenty G, Chen CD, JMJD3 promotes chondrocyte proliferation and hypertrophy during endochondral bone formation in mice. J Mol Cell Biol. 2015 Feb;7(1):23-34 |
1 | J:202210 Zhang X, Ting K, Pathmanathan D, Ko T, Chen W, Chen F, Lee H, James AW, Siu RK, Shen J, Culiat CT, Soo C, Calvarial cleidocraniodysplasia-like defects with ENU-induced Nell-1 deficiency. J Craniofac Surg. 2012 Jan;23(1):61-6 |
1 | J:87592 Zhou HM, Weskamp G, Chesneau V, Sahin U, Vortkamp A, Horiuchi K, Chiusaroli R, Hahn R, Wilkes D, Fisher P, Baron R, Manova K, Basson CT, Hempstead B, Blobel CP, Essential role for ADAM19 in cardiovascular morphogenesis. Mol Cell Biol. 2004 Jan;24(1):96-104 |
1 | J:172282 Zhou ZQ, Shung CY, Ota S, Akiyama H, Keene DR, Hurlin PJ, Sequential and coordinated actions of c-Myc and N-Myc control appendicular skeletal development. PLoS One. 2011;6(4):e18795 |
1 | J:155388 Zhu H, Bendall AJ, Dlx5 Is a cell autonomous regulator of chondrocyte hypertrophy in mice and functionally substitutes for Dlx6 during endochondral ossification. PLoS One. 2009;4(11):e8097 |
Col11a1 collagen, type XI, alpha 1 (Synonyms: C530001D20Rik) | |
Results | Reference |
2* | J:74112 Iyama K, Sumiyoshi H, Khaleduzzaman M, Matsuo N, Ninomiya Y, Yoshioka H, Differential expression of two exons of the alpha1(XI) collagen gene (Col11a1) in the mouse embryo. Matrix Biol. 2001 Feb;20(1):53-61 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1 | J:40590 Perala M, Savontaus M, Metsaranta M, Vuorio E, Developmental regulation of mRNA species for types II, IX and XI collagens during mouse embryogenesis. Biochem J. 1997 May 15;324(Pt 1):209-16 |
1* | J:84724 Rahkonen O, Savontaus M, Abdelwahid E, Vuorio E, Jokinen E, Expression patterns of cartilage collagens and Sox9 during mouse heart development. Histochem Cell Biol. 2003 Aug;120(2):103-10 |
1* | J:37148 Savontaus M, Metsranta M, Vuorio E, Retarded skeletal development in transgenic mice with a type II collagen mutation. Am J Pathol. 1996 Dec;149(6):2169-82 |
1* | J:28954 Yoshioka H, Iyama K, Inoguchi K, Khaleduzzaman M, Ninomiya Y, Ramirez F, Developmental pattern of expression of the mouse alpha 1 (XI) collagen gene (Col11a1). Dev Dyn. 1995 Sep;204(1):41-7 |
Col11a2 collagen, type XI, alpha 2 | |
Results | Reference |
1 | J:157869 Hamada Y, Sumiyoshi H, Matsuo N, Yun-Feng W, Nakashima M, Yanagisawa S, Yoshioka H, The pro-alpha2(XI) collagen gene is expressed in odontoblasts. Biochem Biophys Res Commun. 2010 Feb 5;392(2):166-70 |
1* | J:140470 Imuta Y, Nishioka N, Kiyonari H, Sasaki H, Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124). Dev Dyn. 2008 Dec 18;238(1):210-222 |
1* | J:142326 Iwai T, Murai J, Yoshikawa H, Tsumaki N, Smad7 Inhibits chondrocyte differentiation at multiple steps during endochondral bone formation and down-regulates p38 MAPK pathways. J Biol Chem. 2008 Oct 3;283(40):27154-64 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1 | J:34087 Lui VCH, Ng LJ, Sat EWY, Nicholls J, Cheah KSE, Extensive alternative splicing within the amino-propeptide coding domain of alpha2(XI) procollagen mRNAs. Expression of transcripts encoding truncated pro-alpha chains. J Biol Chem. 1996 Jul 12;271(28):16945-51 |
2 | J:142312 Murai J, Ikegami D, Okamoto M, Yoshikawa H, Tsumaki N, Insulation of the ubiquitous Rxrb promoter from the cartilage-specific adjacent gene, Col11a2. J Biol Chem. 2008 Oct 10;283(41):27677-87 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1 | J:52419 Tsumaki N, Tanaka K, Arikawa-Hirasawa E, Nakase T, Kimura T, Thomas JT, Ochi T, Luyten FP, Yamada Y, Role of CDMP-1 in skeletal morphogenesis: promotion of mesenchymal cell recruitment and chondrocyte differentiation. J Cell Biol. 1999 Jan 11;144(1):161-73 |
Col12a1 collagen, type XII, alpha 1 | |
Results | Reference |
1* | J:11916 Oh SP, Griffith CM, Hay ED, Olsen BR, Tissue-specific expression of type XII collagen during mouse embryonic development. Dev Dyn. 1993 Jan;196(1):37-46 |
Col13a1 collagen, type XIII, alpha 1 | |
Results | Reference |
1 | J:296800 Munezane H, Oizumi H, Wakabayashi T, Nishio S, Hirasawa T, Sato T, Harada A, Yoshida T, Eguchi T, Yamanashi Y, Hashimoto T, Iwatsubo T, Roles of Collagen XXV and Its Putative Receptors PTPsigma/delta in Intramuscular Motor Innervation and Congenital Cranial Dysinnervation Disorder. Cell Rep. 2019 Dec 24;29(13):4362-4376.e6 |
1 | J:74151 Sund M, Vaisanen T, Kaukinen S, Ilves M, Tu H, Autio-Harmainen H, Rauvala H, Pihlajaniemi T, Distinct expression of type XIII collagen in neuronal structures and other tissues during mouse development. Matrix Biol. 2001 Jul;20(4):215-31 |
Col15a1 collagen, type XV, alpha 1 | |
Results | Reference |
1* | J:79414 Muona A, Eklund L, Vaisanen T, Pihlajaniemi T, Developmentally regulated expression of type XV collagen correlates with abnormalities in Col15a1(-/-) mice. Matrix Biol. 2002 Jan;21(1):89-102 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Col17a1 collagen, type XVII, alpha 1 (Synonyms: BP180, Bpag, Bpag2, BPAg2) | |
Results | Reference |
1 | J:338452 Wang D, Li H, Chandel NS, Dou Y, Yi R, MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters. Nat Commun. 2023 Jul 21;14(1):4404 |
Col18a1 collagen, type XVIII, alpha 1 (Synonyms: endostatin) | |
Results | Reference |
1 | J:335626 Castillo V, Diaz-Astudillo P, Corrales-Orovio R, San Martin S, Egana JT, Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin. Cells. 2023 Apr 22;12(9) |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:81999 Miosge N, Simniok T, Sprysch P, Herken R, The collagen type XVIII endostatin domain is co-localized with perlecan in basement membranes in vivo. J Histochem Cytochem. 2003 Mar;51(3):285-96 |
2* | J:332639 Rinta-Jaskari MM, Naillat F, Ruotsalainen HJ, Koivunen JT, Sasaki T, Pietila I, Elamaa HP, Kaur I, Manninen A, Vainio SJ, Pihlajaniemi TA, Temporally and Spatially Regulated Collagen XVIII Isoforms Are Involved in Ureteric Tree Development Via the TSP1-like Domain. Matrix Biol. 2023 Jan 6; |
1 | J:349014 Rinta-Jaskari MM, Naillat F, Ruotsalainen HJ, Ronkainen VP, Heljasvaara R, Akram SU, Izzi V, Miinalainen I, Vainio SJ, Pihlajaniemi TA, Collagen XVIII regulates extracellular matrix integrity in the developing nephrons and impacts nephron progenitor cell behavior. Matrix Biol. 2024 May 22; |
1 | J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10) |
Col19a1 collagen, type XIX, alpha 1 | |
Results | Reference |
1 | J:67329 Sumiyoshi H, Laub F, Yoshioka H, Ramirez F, Embryonic expression of type XIX collagen is transient and confined to muscle cells. Dev Dyn. 2001 Feb;220(2):155-62 |
1 | J:92510 Sumiyoshi H, Mor N, Lee SY, Doty S, Henderson S, Tanaka S, Yoshioka H, Rattan S, Ramirez F, Esophageal muscle physiology and morphogenesis require assembly of a collagen XIX-rich basement membrane zone. J Cell Biol. 2004 Aug 16;166(4):591-600 |
Col20a1 collagen, type XX, alpha 1 (Synonyms: 1700051I12Rik) | |
Results | Reference |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Col22a1 collagen, type XXII, alpha 1 (Synonyms: 2310067L16Rik, C80743) | |
Results | Reference |
1 | J:333369 Lipp SN, Jacobson KR, Colling HA, Tuttle TG, Miles DT, McCreery KP, Calve S, Mechanical loading is required for initiation of extracellular matrix deposition at the developing murine myotendinous junction. Matrix Biol. 2023 Feb;116:28-48 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Col23a1 collagen, type XXIII, alpha 1 (Synonyms: 2810458L13Rik) | |
Results | Reference |
1 | J:226941 Akerberg BN, Sarangam ML, Stankunas K, Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Dev Biol. 2015 Nov 1;407(1):158-72 |
Col24a1 collagen, type XXIV, alpha 1 (Synonyms: 5430404K19Rik) | |
Results | Reference |
1* | J:86359 Koch M, Laub F, Zhou P, Hahn RA, Tanaka S, Burgeson RE, Gerecke DR, Ramirez F, Gordon MK, Collagen XXIV, a vertebrate fibrillar collagen with structural features of invertebrate collagens: selective expression in developing cornea and bone. J Biol Chem. 2003 Oct 31;278(44):43236-44 |
Col25a1 collagen, type XXV, alpha 1 (Synonyms: 2700062B08Rik) | |
Results | Reference |
1 | J:296800 Munezane H, Oizumi H, Wakabayashi T, Nishio S, Hirasawa T, Sato T, Harada A, Yoshida T, Eguchi T, Yamanashi Y, Hashimoto T, Iwatsubo T, Roles of Collagen XXV and Its Putative Receptors PTPsigma/delta in Intramuscular Motor Innervation and Congenital Cranial Dysinnervation Disorder. Cell Rep. 2019 Dec 24;29(13):4362-4376.e6 |
Col28a1 collagen, type XXVIII, alpha 1 | |
Results | Reference |
1* | J:167409 Grimal S, Puech S, Wagener R, Venteo S, Carroll P, Fichard-Carroll A, Collagen XXVIII is a distinctive component of the peripheral nervous system nodes of ranvier and surrounds nonmyelinating glial cells. Glia. 2010 Dec;58(16):1977-87 |
Commd7 COMM domain containing 7 (Synonyms: 2310010I22Rik, mU3) | |
Results | Reference |
1* | J:83990 Ishida C, Ura K, Hirao A, Sasaki H, Toyoda A, Sakaki Y, Niwa H, Li E, Kaneda Y, Genomic organization and promoter analysis of the Dnmt3b gene. Gene. 2003 May 22;310:151-9 |
Comp cartilage oligomeric matrix protein (Synonyms: thrombospondin-5, TSP5) | |
Results | Reference |
1* | J:174146 Heinonen J, Taipaleenmaki H, Roering P, Takatalo M, Harkness L, Sandholm J, Uusitalo-Jarvinen H, Kassem M, Kiviranta I, Laitala-Leinonen T, Saamanen AM, Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes. Osteoarthritis Cartilage. 2011 Aug;19(8):1026-35 |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Cop1 COP1, E3 ubiquitin ligase (Synonyms: Cop1, Rfwd2) | |
Results | Reference |
1 | J:267072 Newton K, Dugger DL, Sengupta-Ghosh A, Ferrando RE, Chu F, Tao J, Lam W, Haller S, Chan S, Sa S, Dunlap D, Eastham-Anderson J, Ngu H, Hung J, French DM, Webster JD, Bolon B, Liu J, Reja R, Kummerfeld S, Chen YJ, Modrusan Z, Lewcock JW, Dixit VM, Ubiquitin ligase COP1 coordinates transcriptional programs that control cell type specification in the developing mouse brain. Proc Natl Acad Sci U S A. 2018 Oct 30;115(44):11244-11249 |
Copg2os2 coatomer protein complex, subunit gamma 2, opposite strand 2 (Synonyms: Copg2as2, Lb9, Mit1) | |
Results | Reference |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
Cops5 COP9 signalosome subunit 5 (Synonyms: COP9 complex S5, CSN5, Jab1, JUN activation binding protein, Sgn5) | |
Results | Reference |
1* | J:90626 Carrabino S, Carminati E, Talarico D, Pardi R, Bianchi E, Expression pattern of the JAB1/CSN5 gene during murine embryogenesis: colocalization with NEDD8. Gene Expr Patterns. 2004 Jul;4(4):423-31 |
Corin corin, serine peptidase (Synonyms: Lrp4) | |
Results | Reference |
1 | J:152844 Driskell RR, Giangreco A, Jensen KB, Mulder KW, Watt FM, Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis. Development. 2009 Aug;136(16):2815-23 |
1* | J:130426 Enshell-Seijffers D, Lindon C, Morgan BA, The serine protease Corin is a novel modifier of the Agouti pathway. Development. 2008 Jan;135(2):217-25 |
1 | J:193958 Huh SH, Narhi K, Lindfors PH, Haara O, Yang L, Ornitz DM, Mikkola ML, Fgf20 governs formation of primary and secondary dermal condensations in developing hair follicles. Genes Dev. 2013 Feb 15;27(4):450-8 |
Coro1a coronin, actin binding protein 1A (Synonyms: Clabp, coronin 1, Lmb3, p57) | |
Results | Reference |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Coro1c coronin, actin binding protein 1C (Synonyms: coronin 3, CRN2) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Coro6 coronin 6 (Synonyms: clipin E) | |
Results | Reference |
1* | J:259125 Yang J, Hung LH, Licht T, Kostin S, Looso M, Khrameeva E, Bindereif A, Schneider A, Braun T, RBM24 is a major regulator of muscle-specific alternative splicing. Dev Cell. 2014 Oct 13;31(1):87-99 |
Cox4i1 cytochrome c oxidase subunit 4I1 (Synonyms: Cox4, Cox4a, COXIV) | |
Results | Reference |
1* | J:76945 Carmona MC, Iglesias R, Obregon MJ, Darlington GJ, Villarroya F, Giralt M, Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein alpha. J Biol Chem. 2002 Jun 14;277(24):21489-98 |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
1* | J:305946 Xu M, Yao J, Shi Y, Yi H, Zhao W, Lin X, Yang Z, The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026 |
Cox7a1 cytochrome c oxidase subunit 7A1 (Synonyms: COX7A, COX7AH, COX7AH, COX7AM) | |
Results | Reference |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Cox8a cytochrome c oxidase subunit 8A (Synonyms: COX8L, COX VIII-L) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
Cox8b cytochrome c oxidase subunit 8B (Synonyms: COX8H, COX VIII-H) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
1 | J:324530 Fonseca TL, Russo SC, Luongo C, Salvatore D, Bianco AC, Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 May 1;163(5) |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
1* | J:236180 Zhou H, Black SM, Benson TW, Weintraub NL, Chen W, Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is Not Required for Brown Adipogenesis but Regulates Brown Adipose Tissue Development and Function. Mol Cell Biol. 2016 Aug 1;36(15):2027-38 |
Cp ceruloplasmin (Synonyms: D3Ertd555e) | |
Results | Reference |
1* | J:268912 Ducharme P, Zarruk JG, David S, Paquin J, The ferroxidase ceruloplasmin influences Reelin processing, cofilin phosphorylation and neuronal organization in the developing brain. Mol Cell Neurosci. 2018 Oct;92:104-113 |
Cpa1 carboxypeptidase A1, pancreatic (Synonyms: 0910001L12Rik) | |
Results | Reference |
1 | J:346123 Darrigrand JF, Salowka A, Torres-Cano A, Tapia-Rojo R, Zhu T, Garcia-Manyes S, Spagnoli FM, Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner. Dev Cell. 2024 Feb 5;59(3):326-338.e5 |
1 | J:191071 Petzold KM, Naumann H, Spagnoli FM, Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas. Development. 2013 Jan 1;140(1):126-35 |
1 | J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356 |
1 | J:147764 Svensson P, Bergqvist I, Norlin S, Edlund H, MFng is dispensable for mouse pancreas development and function. Mol Cell Biol. 2009 Apr;29(8):2129-38 |
1 | J:186391 Tao J, Zhu M, Wang H, Afelik S, Vasievich MP, Chen XW, Zhu G, Jensen J, Ginsburg D, Zhang B, SEC23B is required for the maintenance of murine professional secretory tissues. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):E2001-9 |
Cpa2 carboxypeptidase A2, pancreatic | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
1 | J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356 |
Cpa3 carboxypeptidase A3, mast cell (Synonyms: mast cell carboxypeptidase A, MC-CPA, mMC-CPA) | |
Results | Reference |
1* | J:31166 Jippo T, Mizuno H, Xu Z, Nomura S, Yamamoto M, Kitamura Y, Abundant expression of transcription factor GATA-2 in proliferating but not in differentiated mast cells in tissues of mice: demonstration by in situ hybridization. Blood. 1996 Feb 1;87(3):993-8 |
Cpe carboxypeptidase E (Synonyms: carboxypeptidase H, CPH, Cph-1, Cph1, NF-alpha1) | |
Results | Reference |
2* | J:237213 Selvaraj P, Xiao L, Lee C, Murthy SR, Cawley NX, Lane M, Merchenthaler I, Ahn S, Loh YP, Neurotrophic Factor-alpha1: A Key Wnt-beta-Catenin Dependent Anti-Proliferation Factor and ERK-Sox9 Activated Inducer of Embryonic Neural Stem Cell Differentiation to Astrocytes in Neurodevelopment. Stem Cells. 2017 Mar;35(3):557-571 |
1* | J:285908 Xiao L, Yang X, Sharma VK, Loh YP, Cloning, gene regulation, and neuronal proliferation functions of novel N-terminal-truncated carboxypeptidase E/neurotrophic factor-alphal variants in embryonic mouse brain. FASEB J. 2019 Jan;33(1):808-820 |
Cpeb1 cytoplasmic polyadenylation element binding protein 1 | |
Results | Reference |
1 | J:83946 Tay J, Hodgman R, Sarkissian M, Richter JD, Regulated CPEB phosphorylation during meiotic progression suggests a mechanism for temporal control of maternal mRNA translation. Genes Dev. 2003 Jun 15;17(12):1457-62 |
Cpn1 carboxypeptidase N, polypeptide 1 (Synonyms: 0610011F20Rik, 50 kDa, CPN) | |
Results | Reference |
3* | J:91319 Matthews KW, Drouin SM, Liu C, Martin JF, Skidgel RA, Wetsel RA, Expression of the third complement component (C3) and carboxypeptidase N small subunit (CPN1) during mouse embryonic development. Dev Comp Immunol. 2004 May 17;28(6):647-55 |
Cpne5 copine V (Synonyms: A830083G22Rik, MGC:47475) | |
Results | Reference |
1* | J:139991 Ding X, Jin Y, Wu Y, Wu Y, Wu H, Xiong L, Song X, Liu S, Fan W, Fan M, Localization and cellular distribution of CPNE5 in embryonic mouse brain. Brain Res. 2008 Aug 11;1224:20-8 |
2 | J:330742 Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM, In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022 Oct 17;132(20):e156955 |
2* | J:306155 Goodyer WR, Beyersdorf BM, Paik DT, Tian L, Li G, Buikema JW, Chirikian O, Choi S, Venkatraman S, Adams EL, Tessier-Lavigne M, Wu JC, Wu SM, Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution. Circ Res. 2019 Aug 2;125(4):379-397 |
Cps1 carbamoyl-phosphate synthetase 1 (Synonyms: 4732433M03Rik, CPS, CPSase I, D1Ucla3) | |
Results | Reference |
2* | J:262663 Burke ZD, Reed KR, Yeh SW, Meniel V, Sansom OJ, Clarke AR, Tosh D, Spatiotemporal regulation of liver development by the Wnt/beta-catenin pathway. Sci Rep. 2018 Feb 9;8(1):2735 |
Cpt1a carnitine palmitoyltransferase 1a, liver (Synonyms: Cpt1, CPTI, L-CPT I) | |
Results | Reference |
1 | J:244845 Wong BW, Wang X, Zecchin A, Thienpont B, Cornelissen I, Kalucka J, Garcia-Caballero M, Missiaen R, Huang H, Bruning U, Blacher S, Vinckier S, Goveia J, Knobloch M, Zhao H, Dierkes C, Shi C, Hagerling R, Moral-Darde V, Wyns S, Lippens M, Jessberger S, Fendt SM, Luttun A, Noel A, Kiefer F, Ghesquiere B, Moons L, Schoonjans L, Dewerchin M, Eelen G, Lambrechts D, Carmeliet P, The role of fatty acid beta-oxidation in lymphangiogenesis. Nature. 2017 Feb 02;542(7639):49-54 |
Cpt1b carnitine palmitoyltransferase 1b, muscle (Synonyms: Cpt1, M-CPT I, M-CPTI) | |
Results | Reference |
1* | J:65091 Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP, Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest. 2000 Oct;106(7):847-56 |
Cpxm1 carboxypeptidase X, M14 family member 1 (Synonyms: Cpx-1) | |
Results | Reference |
1* | J:53201 Lei Y, Xin X, Morgan D, Pintar JE, Fricker LD, Identification of mouse CPX-1, a novel member of the metallocarboxypeptidase gene family with highest similarity to CPX-2. DNA Cell Biol. 1999 Feb;18(2):175-85 |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Crabp1 cellular retinoic acid binding protein I (Synonyms: Crabp-1, CrabpI, Rbp-5) | |
Results | Reference |
1 | J:20940 Bloch-Zupan A, Decimo D, Loriot M, Mark MP, Ruch JV, Expression of nuclear retinoic acid receptors during mouse odontogenesis. Differentiation. 1994 Sep;57(3):195-203 |
1* | J:32533 Dencker L, Annerwall E, Busch C, Eriksson U, Localization of specific retinoid-binding sites and expression of cellular retinoic-acid-binding protein (CRABP) in the early mouse embryo. Development. 1990 Oct;110(2):343-52 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:44591 Garel S, Marin F, Grosschedl R, Charnay P, Ebf1 controls early cell differentiation in the embryonic striatum. Development. 1999 Dec;126(23):5285-94 |
1 | J:121381 Hu P, Zhang M, Napoli JL, Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal. Biochim Biophys Acta. 2007 Apr;1770(4):694-705 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:89666 Romand R, Sapin V, Ghyselinck NB, Avan P, Le Calvez S, Dolle P, Chambon P, Mark M, Spatio-temporal distribution of cellular retinoid binding protein gene transcripts in the developing and the adult cochlea. Morphological and functional consequences in CRABP- and CRBPI-null mutant mice. Eur J Neurosci. 2000 Aug;12(8):2793-804 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1* | J:16894 Yamagata T, Momoi MY, Yanagisawa M, Kumagai H, Yamakado M, Momoi T, Changes of the expression and distribution of retinoic acid receptors during neurogenesis in mouse embryos. Brain Res Dev Brain Res. 1994 Feb 18;77(2):163-76 |
Crabp2 cellular retinoic acid binding protein II (Synonyms: Crabp-2, CrabpII) | |
Results | Reference |
1 | J:321578 Ang PS, Matrongolo MJ, Tischfield MA, The growth and expansion of meningeal lymphatic networks are affected in craniosynostosis. Development. 2022 Jan 1;149(1):dev200065 |
1 | J:20940 Bloch-Zupan A, Decimo D, Loriot M, Mark MP, Ruch JV, Expression of nuclear retinoic acid receptors during mouse odontogenesis. Differentiation. 1994 Sep;57(3):195-203 |
1* | J:20074 Giguere V, Lyn S, Yip P, Siu CH, Amin S, Molecular cloning of cDNA encoding a second cellular retinoic acid-binding protein. Proc Natl Acad Sci U S A. 1990 Aug;87(16):6233-7 |
1 | J:229100 Goto M, Hojo M, Ando M, Kita A, Kitagawa M, Ohtsuka T, Kageyama R, Miyamoto S, Hes1 and Hes5 are required for differentiation of pituicytes and formation of the neurohypophysis in pituitary development. Brain Res. 2015 Nov 2;1625:206-17 |
1 | J:121381 Hu P, Zhang M, Napoli JL, Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal. Biochim Biophys Acta. 2007 Apr;1770(4):694-705 |
1 | J:89666 Romand R, Sapin V, Ghyselinck NB, Avan P, Le Calvez S, Dolle P, Chambon P, Mark M, Spatio-temporal distribution of cellular retinoid binding protein gene transcripts in the developing and the adult cochlea. Morphological and functional consequences in CRABP- and CRBPI-null mutant mice. Eur J Neurosci. 2000 Aug;12(8):2793-804 |
Crb1 crumbs family member 1, photoreceptor morphogenesis associated (Synonyms: 7530426H14Rik, A930008G09Rik) | |
Results | Reference |
1* | J:73806 den Hollander AI, Ghiani M, de Kok YJ, Wijnholds J, Ballabio A, Cremers FP, Broccoli V, Isolation of Crb1, a mouse homologue of Drosophila crumbs, and analysis of its expression pattern in eye and brain. Mech Dev. 2002 Jan;110(1-2):203-7 |
1* | J:283394 Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S, Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162 |
1* | J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347 |
Crb2 crumbs family member 2 | |
Results | Reference |
1* | J:283394 Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S, Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162 |
1* | J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347 |
Crb3 crumbs family member 3 | |
Results | Reference |
1* | J:283394 Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S, Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162 |
1* | J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347 |
1 | J:239794 Szymaniak AD, Mahoney JE, Cardoso WV, Varelas X, Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap. Dev Cell. 2015 Aug 10;34(3):283-96 |
1 | J:302296 Vong KI, Ma TC, Li B, Leung TCN, Nong W, Ngai SM, Hui JHL, Jiang L, Kwan KM, SOX9-COL9A3-dependent regulation of choroid plexus epithelial polarity governs blood-cerebrospinal fluid barrier integrity. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2009568118 |
Creb1 cAMP responsive element binding protein 1 (Synonyms: 2310001E10Rik, 3526402H21Rik, Creb, Creb-1) | |
Results | Reference |
1* | J:171712 Bird AD, Flecknoe SJ, Tan KH, Olsson PF, Antony N, Mantamadiotis T, Hooper SB, Cole TJ, cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development. PLoS One. 2011;6(3):e17843 |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1 | J:353354 Desiderio S, Schwaller F, Tartour K, Padmanabhan K, Lewin GR, Carroll P, Marmigere F, Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2. Elife. 2024 Feb 22;12 |
1 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1 | J:336092 Knowles SJ, Stafford AM, Zaman T, Angara K, Williams MR, Newbern JM, Vogt D, Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs. Development. 2023 May 15;150(10):dev201371 |
1* | J:272498 Landeira BS, Santana TTDS, Araujo JAM, Tabet EI, Tannous BA, Schroeder T, Costa MR, Activity-Independent Effects of CREB on Neuronal Survival and Differentiation during Mouse Cerebral Cortex Development. Cereb Cortex. 2018 Feb 1;28(2):538-548 |
1 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
1 | J:109567 Shen WB, Plachez C, Mongi AS, Richards LJ, Identification of candidate genes at the corticoseptal boundary during development. Gene Expr Patterns. 2006 Jun;6(5):471-81 |
Creb3l1 cAMP responsive element binding protein 3-like 1 (Synonyms: BBF-2 (drosophila) homolog, MGC:25246, Oasis) | |
Results | Reference |
2 | J:83512 Hikake T, Mori T, Iseki K, Hagino S, Zhang Y, Takagi H, Yokoya S, Wanaka A, Comparison of expression patterns between CREB family transcription factor OASIS and proteoglycan core protein genes during murine tooth development. Anat Embryol (Berl). 2003 Apr;206(5):373-80 |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
1* | J:74179 Nikaido T, Yokoya S, Mori T, Hagino S, Iseki K, Zhang Y, Takeuchi M, Takaki H, Kikuchi S, Wanaka A, Expression of the novel transcription factor OASIS, which belongs to the CREB/ATF family, in mouse embryo with special reference to bone development. Histochem Cell Biol. 2001 Aug;116(2):141-8 |
2 | J:205632 Saito A, Kanemoto S, Kawasaki N, Asada R, Iwamoto H, Oki M, Miyagi H, Izumi S, Sanosaka T, Nakashima K, Imaizumi K, Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun. 2012;3:967 |
Creb3l2 cAMP responsive element binding protein 3-like 2 (Synonyms: BBF2H7, C530025K05Rik) | |
Results | Reference |
1 | J:158241 Saito A, Hino S, Murakami T, Kanemoto S, Kondo S, Saitoh M, Nishimura R, Yoneda T, Furuichi T, Ikegawa S, Ikawa M, Okabe M, Imaizumi K, Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis. Nat Cell Biol. 2009 Oct;11(10):1197-204 |
Creb3l3 cAMP responsive element binding protein 3-like 3 (Synonyms: CREB-H, D10Bur1e) | |
Results | Reference |
1* | J:154372 Li X, Udager AM, Hu C, Qiao XT, Richards N, Gumucio DL, Dynamic patterning at the pylorus: Formation of an epithelial intestine-stomach boundary in late fetal life. Dev Dyn. 2009 Oct 29;238(12):3205-3217 |
1* | J:140018 Luebke-Wheeler J, Zhang K, Battle M, Si-Tayeb K, Garrison W, Chhinder S, Li J, Kaufman RJ, Duncan SA, Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H. Hepatology. 2008 Oct;48(4):1242-50 |
Creb5 cAMP responsive element binding protein 5 (Synonyms: 9430076C15Rik, Crebpa, D430026C09Rik) | |
Results | Reference |
1 | J:331689 Zhang CH, Gao Y, Hung HH, Zhuo Z, Grodzinsky AJ, Lassar AB, Creb5 coordinates synovial joint formation with the genesis of articular cartilage. Nat Commun. 2022 Nov 26;13(1):7295 |
Crebbp CREB binding protein (Synonyms: CBP, KAT3A) | |
Results | Reference |
1* | J:147999 Chen G, Zhu J, Lv T, Wu G, Sun H, Huang X, Tian J, Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts. J Biomed Sci. 2009;16:24 |
1 | J:181099 Chen Z, Gao B, Zhou X, Expression patterns of histone acetyltransferases p300 and CBP during murine tooth development. In Vitro Cell Dev Biol Anim. 2012 Jan;48(1):61-8 |
1 | J:331267 de Thonel A, Ahlskog JK, Daupin K, Dubreuil V, Berthelet J, Chaput C, Pires G, Leonetti C, Abane R, Barris LC, Leray I, Aalto AL, Naceri S, Cordonnier M, Benasolo C, Sanial M, Duchateau A, Vihervaara A, Puustinen MC, Miozzo F, Fergelot P, Lebigot E, Verloes A, Gressens P, Lacombe D, Gobbo J, Garrido C, Westerheide SD, David L, Petitjean M, Taboureau O, Rodrigues-Lima F, Passemard S, Saberan-Djoneidi D, Nguyen L, Lancaster M, Sistonen L, Mezger V, CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder. Nat Commun. 2022 Nov 16;13(1):7002 |
1* | J:189008 Jia Y, Viswakarma N, Crawford SE, Sarkar J, Sambasiva Rao M, Karpus WJ, Kanwar YS, Zhu YJ, Reddy JK, Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. Mech Dev. 2012 Sep;129(9-12):193-207 |
1 | J:263867 Merk DJ, Ohli J, Merk ND, Thatikonda V, Morrissy S, Schoof M, Schmid SN, Harrison L, Filser S, Ahlfeld J, Erkek S, Raithatha K, Andreska T, Weisshaar M, Launspach M, Neumann JE, Shakarami M, Plenker D, Marra MA, Li Y, Mungall AJ, Moore RA, Ma Y, Jones SJM, Lutz B, Ertl-Wagner B, Rossi A, Wagener R, Siebert R, Jung A, Eberhart CG, Lach B, Sendtner M, Pfister SM, Taylor MD, Chavez L, Kool M, Schuller U, Opposing Effects of CREBBP Mutations Govern the Phenotype of Rubinstein-Taybi Syndrome and Adult SHH Medulloblastoma. Dev Cell. 2018 Mar 26;44(6):709-724.e6 |
1* | J:60120 Partanen M, Motoyama J, Hui CC, Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis. Int J Dev Biol. 1999 Sep;43(6):487-94 |
1 | J:296487 Schoof M, Launspach M, Holdhof D, Nguyen L, Engel V, Filser S, Peters F, Immenschuh J, Hellwig M, Niesen J, Mall V, Ertl-Wagner B, Hagel C, Spohn M, Lutz B, Sedlacik J, Indenbirken D, Merk DJ, Schuller U, The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration. Acta Neuropathol Commun. 2019 Dec 5;7(1):199 |
1* | J:300844 Takagi T, Higashi Y, Asai M, Ishii S, Introduction of a de novo Creb-binding protein gene mutation in sperm to produce a Rubinstein-Taybi syndrome model using inbred C57BL/6 mice. Brain Res. 2020 Dec 15;1749:147140 |
Crebzf CREB/ATF bZIP transcription factor (Synonyms: 1110034C16Rik, 6330417B10Rik, LAZip, LAZipII, Zf) | |
Results | Reference |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Creg1 cellular repressor of E1A-stimulated genes 1 (Synonyms: Creg) | |
Results | Reference |
1 | J:317416 Liu J, Qi Y, Chao J, Sathuvalli P, Y Lee L, Li S, CREG1 promotes lysosomal biogenesis and function. Autophagy. 2021 Dec;17(12):4249-4265 |
Creg2 cellular repressor of E1A-stimulated genes 2 (Synonyms: A830098L22Rik) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Crh corticotropin releasing hormone (Synonyms: corticotropin releasing factor, corticotropin-releasing factor, CRF, LOC383938) | |
Results | Reference |
1 | J:18319 Keegan CE, Herman JP, Karolyi IJ, O'Shea KS, Camper SA, Seasholtz AF, Differential expression of corticotropin-releasing hormone in developing mouse embryos and adult brain. Endocrinology. 1994 Jun;134(6):2547-55 |
1 | J:134188 Reichardt HM, Schutz G, Feedback control of glucocorticoid production is established during fetal development. Mol Med. 1996 Nov;2(6):735-44 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
2* | J:168512 Simard M, Cote M, Provost PR, Tremblay Y, Expression of genes related to the hypothalamic-pituitary-adrenal axis in murine fetal lungs in late gestation. Reprod Biol Endocrinol. 2010;8:134 |
1* | J:286599 Song NN, Ma P, Zhang Q, Zhang L, Wang H, Zhang L, Zhu L, He CH, Mao B, Ding YQ, Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199 |
Crhbp corticotropin releasing hormone binding protein (Synonyms: CRH-BP) | |
Results | Reference |
2* | J:168512 Simard M, Cote M, Provost PR, Tremblay Y, Expression of genes related to the hypothalamic-pituitary-adrenal axis in murine fetal lungs in late gestation. Reprod Biol Endocrinol. 2010;8:134 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Crhr1 corticotropin releasing hormone receptor 1 (Synonyms: CRF1R, CRF 1 receptor, CRFR1, CRF-R1alpha) | |
Results | Reference |
1 | J:88219 King JS, Bishop GA, Localization of the type 1 corticotropin releasing factor receptor (CRF-R1) in the embryonic mouse cerebellum. J Neurocytol. 2003 Mar;32(3):305-16 |
1* | J:308609 Sararols P, Stevant I, Neirijnck Y, Rebourcet D, Darbey A, Curley MK, Kuhne F, Dermitzakis E, Smith LB, Nef S, Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells. Front Cell Dev Biol. 2021;9:695546 |
2* | J:168512 Simard M, Cote M, Provost PR, Tremblay Y, Expression of genes related to the hypothalamic-pituitary-adrenal axis in murine fetal lungs in late gestation. Reprod Biol Endocrinol. 2010;8:134 |
Crhr2 corticotropin releasing hormone receptor 2 (Synonyms: CRF 2 receptor, Crfr2, CRF-R2, CRFR2alpha, CRFR2beta, CRH-R2) | |
Results | Reference |
2* | J:168512 Simard M, Cote M, Provost PR, Tremblay Y, Expression of genes related to the hypothalamic-pituitary-adrenal axis in murine fetal lungs in late gestation. Reprod Biol Endocrinol. 2010;8:134 |
Crim1 cysteine rich transmembrane BMP regulator 1 | |
Results | Reference |
1 | J:250155 Iyer S, Chou FY, Wang R, Chiu HS, Raju VK, Little MH, Thomas WG, Piper M, Pennisi DJ, Crim1 has cell-autonomous and paracrine roles during embryonic heart development. Sci Rep. 2016 Jan 29;6:19832 |
1* | J:117237 Pennisi DJ, Wilkinson L, Kolle G, Sohaskey ML, Gillinder K, Piper MJ, McAvoy JW, Lovicu FJ, Little MH, Crim1(KST264/KST264) mice display a disruption of the Crim1 gene resulting in perinatal lethality with defects in multiple organ systems. Dev Dyn. 2007 Feb;236(2):502-11 |
Cripto cripto, EGF-CFC family member (Synonyms: CR1, Tdgf1) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:21479 Johnson SE, Rothstein JL, Knowles BB, Expression of epidermal growth factor family gene members in early mouse development. Dev Dyn. 1994 Nov;201(3):216-26 |
1* | J:320172 Souquet B, Tourpin S, Messiaen S, Moison D, Habert R, Livera G, Nodal signaling regulates the entry into meiosis in fetal germ cells. Endocrinology. 2012 May;153(5):2466-73 |
1* | J:316962 Spiller CM, Gillis AJ, Burnet G, Stoop H, Koopman P, Bowles J, Looijenga LH, Cripto: Expression, epigenetic regulation and potential diagnostic use in testicular germ cell tumors. Mol Oncol. 2016 Apr;10(4):526-37 |
Crispld2 cysteine-rich secretory protein LCCL domain containing 2 (Synonyms: 1810049K24Rik, coffeecrisp, Lgl1) | |
Results | Reference |
1* | J:279119 Seow BKL, McDougall ARA, Short KL, Wallace MJ, Hooper SB, Cole TJ, Identification of Betamethasone-Regulated Target Genes and Cell Pathways in Fetal Rat Lung Mesenchymal Fibroblasts. Endocrinology. 2019 Aug 1;160(8):1868-1884 |
Crk v-crk avian sarcoma virus CT10 oncogene homolog (Synonyms: Crk-I, Crk-II, Crk-III, Crko, proto-oncogene c-crk) | |
Results | Reference |
1* | J:29533 de Jong R, Haataja L, Voncken JW, Heisterkamp N, Groffen J, Tyrosine phosphorylation of murine Crkl. Oncogene. 1995 Oct 19;11(8):1469-74 |
1 | J:145031 Feng L, Cooper JA, Dual functions of Dab1 during brain development. Mol Cell Biol. 2009 Jan;29(2):324-32 |
Crkl v-crk avian sarcoma virus CT10 oncogene homolog-like (Synonyms: 1110025F07Rik, Crkol, snoop) | |
Results | Reference |
1* | J:29533 de Jong R, Haataja L, Voncken JW, Heisterkamp N, Groffen J, Tyrosine phosphorylation of murine Crkl. Oncogene. 1995 Oct 19;11(8):1469-74 |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
1 | J:132843 Yip YP, Kronstadt-O'Brien P, Capriotti C, Cooper JA, Yip JW, Migration of sympathetic preganglionic neurons in the spinal cord is regulated by Reelin-dependent Dab1 tyrosine phosphorylation and CrkL. J Comp Neurol. 2007 Jun 1;502(4):635-43 |
Crlf1 cytokine receptor-like factor 1 (Synonyms: CLF-1, CRLM3, cytokine receptor like molecule 3) | |
Results | Reference |
2* | J:99504 de Bovis B, Derouet D, Gauchat JF, Elson G, Gascan H, Delapeyriere O, clc is co-expressed with clf or cntfr in developing mouse muscles. Cell Commun Signal. 2005 Jan 31;3(1):1 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Crmp1 collapsin response mediator protein 1 (Synonyms: DRP-1, Ulip3) | |
Results | Reference |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
2 | J:116689 Yamashita N, Uchida Y, Ohshima T, Hirai S, Nakamura F, Taniguchi M, Mikoshiba K, Honnorat J, Kolattukudy P, Thomasset N, Takei K, Takahashi T, Goshima Y, Collapsin response mediator protein 1 mediates reelin signaling in cortical neuronal migration. J Neurosci. 2006 Dec 20;26(51):13357-62 |
2 | J:293780 Yamazaki Y, Nagai J, Akinaga S, Koga Y, Hasegawa M, Takahashi M, Yamashita N, Kolattukudy P, Goshima Y, Ohshima T, Phosphorylation of CRMP2 is required for migration and positioning of Purkinje cells: Redundant roles of CRMP1 and CRMP4. Brain Res. 2020 Jun 1;1736:146762 |
Crnde colorectal neoplasia differentially expressed, non-protein coding (Synonyms: 4933436C20Rik) | |
Results | Reference |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
Crnn cornulin (Synonyms: LOC381457) | |
Results | Reference |
1* | J:215938 Mlitz V, Strasser B, Jaeger K, Hermann M, Ghannadan M, Buchberger M, Alibardi L, Tschachler E, Eckhart L, Trichohyalin-like proteins have evolutionarily conserved roles in the morphogenesis of skin appendages. J Invest Dermatol. 2014 Nov;134(11):2685-92 |
Crtc2 CREB regulated transcription coactivator 2 (Synonyms: 4632407F12Rik) | |
Results | Reference |
1 | J:363706 Ruan X, Hu K, Yang Y, Yang R, Tseng E, Kang B, Kauffman A, Zhong R, Zhang X, Cell-Type-Specific Splicing of Transcription Regulators and Ptbp1 by Rbfox1/2/3 in the Developing Neocortex. J Neurosci. 2025 Feb 12;45(7) |
Crx cone-rod homeobox (Synonyms: Crx1) | |
Results | Reference |
1* | J:169188 Bandah-Rozenfeld D, Mizrahi-Meissonnier L, Farhy C, Obolensky A, Chowers I, Pe'er J, Merin S, Ben-Yosef T, Ashery-Padan R, Banin E, Sharon D, Homozygosity mapping reveals null mutations in FAM161A as a cause of autosomal-recessive retinitis pigmentosa. Am J Hum Genet. 2010 Sep 10;87(3):382-91 |
1 | J:341148 Bosze B, Suarez-Navarro J, Cajias I, Brzezinski Iv JA, Brown NL, Notch pathway mutants do not equivalently perturb mouse embryonic retinal development. PLoS Genet. 2023 Sep;19(9):e1010928 |
1 | J:176438 Esteve P, Sandonis A, Ibanez C, Shimono A, Guerrero I, Bovolenta P, Secreted frizzled-related proteins are required for Wnt/{beta}-catenin signalling activation in the vertebrate optic cup. Development. 2011 Oct;138(19):4179-84 |
1 | J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489 |
2 | J:285747 Liu S, Liu X, Li S, Huang X, Qian H, Jin K, Xiang M, Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5016-5027 |
1 | J:214082 Maurer KA, Riesenberg AN, Brown NL, Notch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina. Development. 2014 Aug;141(16):3243-54 |
1 | J:142509 Oron-Karni V, Farhy C, Elgart M, Marquardt T, Remizova L, Yaron O, Xie Q, Cvekl A, Ashery-Padan R, Dual requirement for Pax6 in retinal progenitor cells. Development. 2008 Dec;135(24):4037-47 |
1 | J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77 |
1 | J:281878 Yook C, Kim K, Kim D, Kang H, Kim SG, Kim E, Kim SY, A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice. Front Mol Neurosci. 2019;12:241 |
1 | J:309104 Zheng MH, Shi M, Pei Z, Gao F, Han H, Ding YQ, The transcription factor RBP-J is essential for retinal cell differentiation and lamination. Mol Brain. 2009 Dec 18;2:38 |
Crxos cone-rod homeobox, opposite strand (Synonyms: Crxos1, Egam1) | |
Results | Reference |
3 | J:180846 Saito K, Ogawa A, Toyofuku K, Hosoi Y, Soma M, Iha M, Kasuga K, Kojima I, Kobayashi M, Relationships between homeoprotein EGAM1C and the expression of the placental prolactin gene family in mouse placentae and trophoblast stem cells. Reproduction. 2011 Feb;141(2):259-68 |
Cry1 cryptochrome circadian regulator 1 (Synonyms: Phll1) | |
Results | Reference |
1* | J:158725 Dolatshad H, Cary AJ, Davis FC, Differential expression of the circadian clock in maternal and embryonic tissues of mice. PLoS One. 2010;5(3):e9855 |
1* | J:161413 Ratajczak CK, Herzog ED, Muglia LJ, Clock gene expression in gravid uterus and extra-embryonic tissues during late gestation in the mouse. Reprod Fertil Dev. 2010;22(5):743-50 |
2 | J:329949 Yuan H, Xie B, Yu X, Lin C, Li M, Zhang Y, Zou X, Lu M, Zhao M, Wen X, A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development. Front Physiol. 2022;13:981311 |
Cry2 cryptochrome circadian regulator 2 (Synonyms: D130054K12Rik) | |
Results | Reference |
1* | J:161413 Ratajczak CK, Herzog ED, Muglia LJ, Clock gene expression in gravid uterus and extra-embryonic tissues during late gestation in the mouse. Reprod Fertil Dev. 2010;22(5):743-50 |
Cryaa crystallin, alpha A (Synonyms: Acry-1, alpha-A-crystallin, Crya-1, Crya1, DAcry-1) | |
Results | Reference |
1 | J:228518 Arya P, Rainey MA, Bhattacharyya S, Mohapatra BC, George M, Kuracha MR, Storck MD, Band V, Govindarajan V, Band H, The endocytic recycling regulatory protein EHD1 Is required for ocular lens development. Dev Biol. 2015 Dec 1;408(1):41-55 |
1 | J:30314 Chow RL, Roux GD, Roghani M, Palmer MA, Rifkin DB, Moscatelli DA, Lang RA, FGF suppresses apoptosis and induces differentiation of fibre cells in the mouse lens. Development. 1995 Dec;121(12):4383-93 |
1* | J:56095 Kawauchi S, Takahashi S, Nakajima O, Ogino H, Morita M, Nishizawa M, Yasuda K, Yamamoto M, Regulation of lens fiber cell differentiation by transcription factor c-Maf. J Biol Chem. 1999 Jul 2;274(27):19254-60 |
1* | J:270646 Limi S, Senecal A, Coleman R, Lopez-Jones M, Guo P, Polumbo C, Singer RH, Skoultchi AI, Cvekl A, Transcriptional burst fraction and size dynamics during lens fiber cell differentiation and detailed insights into the denucleation process. J Biol Chem. 2018 Aug 24;293(34):13176-13190 |
2 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
1* | J:23615 Morgenbesser SD, Schreiber-Agus N, Bidder M, Mahon KA, Overbeek PA, Horner J, DePinho RA, Contrasting roles for c-Myc and L-Myc in the regulation of cellular growth and differentiation in vivo. EMBO J. 1995 Feb 15;14(4):743-56 |
Cryab crystallin, alpha B (Synonyms: alpha B-crystallin, Crya-2, Crya2, HspB5) | |
Results | Reference |
1* | J:37520 Benjamin IJ, Shelton J, Garry DJ, Richardson JA, Temporospatial expression of the small HSP/alpha B-crystallin in cardiac and skeletal muscle during mouse development. Dev Dyn. 1997 Jan;208(1):75-84 |
1* | J:56095 Kawauchi S, Takahashi S, Nakajima O, Ogino H, Morita M, Nishizawa M, Yasuda K, Yamamoto M, Regulation of lens fiber cell differentiation by transcription factor c-Maf. J Biol Chem. 1999 Jul 2;274(27):19254-60 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
Cryba1 crystallin, beta A1 (Synonyms: BA3/A1, Cryb) | |
Results | Reference |
1* | J:56095 Kawauchi S, Takahashi S, Nakajima O, Ogino H, Morita M, Nishizawa M, Yasuda K, Yamamoto M, Regulation of lens fiber cell differentiation by transcription factor c-Maf. J Biol Chem. 1999 Jul 2;274(27):19254-60 |
1* | J:270646 Limi S, Senecal A, Coleman R, Lopez-Jones M, Guo P, Polumbo C, Singer RH, Skoultchi AI, Cvekl A, Transcriptional burst fraction and size dynamics during lens fiber cell differentiation and detailed insights into the denucleation process. J Biol Chem. 2018 Aug 24;293(34):13176-13190 |
Crybb1 crystallin, beta B1 (Synonyms: 3110006K12Rik) | |
Results | Reference |
2* | J:34072 Duncan MK, Li X, Ogino H, Yasuda K, Piatigorsky J, Developmental regulation of the chicken beta B1-crystallin promoter in transgenic mice. Mech Dev. 1996 Jun;57(1):79-89 |
2 | J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134 |
1 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
Crybb2 crystallin, beta B2 (Synonyms: Aey2, betaB2-crystallin, Cryb-2) | |
Results | Reference |
2 | J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134 |
1 | J:201986 Sun M, Holter SM, Stepan J, Garrett L, Genius J, Kremmer E, Hrabe de Angelis M, Wurst W, Lie DC, Bally-Cuif L, Eder M, Rujescu D, Graw J, Crybb2 coding for betaB2-crystallin affects sensorimotor gating and hippocampal function. Mamm Genome. 2013 Oct;24(9-10):333-48 |
Crybb3 crystallin, beta B3 | |
Results | Reference |
2 | J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134 |
Cryg crystallin gamma complex | |
Results | Reference |
1 | J:228518 Arya P, Rainey MA, Bhattacharyya S, Mohapatra BC, George M, Kuracha MR, Storck MD, Band V, Govindarajan V, Band H, The endocytic recycling regulatory protein EHD1 Is required for ocular lens development. Dev Biol. 2015 Dec 1;408(1):41-55 |
1* | J:225905 Dash S, Dang CA, Beebe DC, Lachke SA, Deficiency of the RNA binding protein caprin2 causes lens defects and features of peters anomaly. Dev Dyn. 2015 Oct;244(10):1313-27 |
1* | J:253196 Dubail J, Vasudevan D, Wang LW, Earp SE, Jenkins MW, Haltiwanger RS, Apte SS, Impaired ADAMTS9 secretion: A potential mechanism for eye defects in Peters Plus Syndrome. Sci Rep. 2016 Sep 30;6:33974 |
1 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
1* | J:335071 Siddam AD, Duot M, Coomson SY, Anand D, Aryal S, Weatherbee BAT, Audic Y, Paillard L, Lachke SA, High-Throughput Transcriptomics of Celf1 Conditional Knockout Lens Identifies Downstream Networks Linked to Cataract Pathology. Cells. 2023 Apr 1;12(7) |
1 | J:122566 Simirskii VN, Wang Y, Duncan MK, Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype. Dev Biol. 2007 Jun 15;306(2):658-68 |
1 | J:343554 Sun Q, Li J, Ma J, Zheng Y, Ju R, Li X, Ren X, Huang L, Chen R, Tan X, Luo L, JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development. Invest Ophthalmol Vis Sci. 2023 Dec 1;64(15):15 |
1 | J:345586 Wazin F, Lovicu FJ, Conditional Ablation of Spred1 and Spred2 in the Eye Lens Negatively Impacts Its Development and Growth. Cells. 2024 Feb 6;13(4) |
Cryga crystallin, gamma A (Synonyms: Cryg-4, DGcry-4, Secc) | |
Results | Reference |
1* | J:56095 Kawauchi S, Takahashi S, Nakajima O, Ogino H, Morita M, Nishizawa M, Yasuda K, Yamamoto M, Regulation of lens fiber cell differentiation by transcription factor c-Maf. J Biol Chem. 1999 Jul 2;274(27):19254-60 |
1* | J:270646 Limi S, Senecal A, Coleman R, Lopez-Jones M, Guo P, Polumbo C, Singer RH, Skoultchi AI, Cvekl A, Transcriptional burst fraction and size dynamics during lens fiber cell differentiation and detailed insights into the denucleation process. J Biol Chem. 2018 Aug 24;293(34):13176-13190 |
1 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
Crygb crystallin, gamma B (Synonyms: Cryg-3, DGcry-3) | |
Results | Reference |
1* | J:56095 Kawauchi S, Takahashi S, Nakajima O, Ogino H, Morita M, Nishizawa M, Yasuda K, Yamamoto M, Regulation of lens fiber cell differentiation by transcription factor c-Maf. J Biol Chem. 1999 Jul 2;274(27):19254-60 |
1 | J:350084 Zhang L, Liu X, Li W, Liu K, Zhang J, Liu X, Wang J, Integrative transcriptomic profiling of ncRNAs and mRNAs in developing mouse lens. Front Genet. 2024;15:1405715 |
Crygc crystallin, gamma C (Synonyms: Cryg-5) | |
Results | Reference |
1* | J:56095 Kawauchi S, Takahashi S, Nakajima O, Ogino H, Morita M, Nishizawa M, Yasuda K, Yamamoto M, Regulation of lens fiber cell differentiation by transcription factor c-Maf. J Biol Chem. 1999 Jul 2;274(27):19254-60 |
1 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
Crygd crystallin, gamma D (Synonyms: Aey4, Cryg-1, DGcry-1) | |
Results | Reference |
1* | J:56095 Kawauchi S, Takahashi S, Nakajima O, Ogino H, Morita M, Nishizawa M, Yasuda K, Yamamoto M, Regulation of lens fiber cell differentiation by transcription factor c-Maf. J Biol Chem. 1999 Jul 2;274(27):19254-60 |
1 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Cryge crystallin, gamma E (Synonyms: Cryg-6) | |
Results | Reference |
1* | J:56095 Kawauchi S, Takahashi S, Nakajima O, Ogino H, Morita M, Nishizawa M, Yasuda K, Yamamoto M, Regulation of lens fiber cell differentiation by transcription factor c-Maf. J Biol Chem. 1999 Jul 2;274(27):19254-60 |
Crygf crystallin, gamma F (Synonyms: 3110001K11Rik, Cryg-2, DGcry-2, Len-2) | |
Results | Reference |
1* | J:56095 Kawauchi S, Takahashi S, Nakajima O, Ogino H, Morita M, Nishizawa M, Yasuda K, Yamamoto M, Regulation of lens fiber cell differentiation by transcription factor c-Maf. J Biol Chem. 1999 Jul 2;274(27):19254-60 |
Crym crystallin, mu | |
Results | Reference |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:98698 Muzio L, Mallamaci A, Foxg1 confines Cajal-Retzius neuronogenesis and hippocampal morphogenesis to the dorsomedial pallium. J Neurosci. 2005 Apr 27;25(17):4435-41 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Cs citrate synthase (Synonyms: 2610511A05Rik, 9030605P22Rik, ahl4, Cis) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
Csdc2 cold shock domain containing C2, RNA binding | |
Results | Reference |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
Csf1 colony stimulating factor 1 (macrophage) (Synonyms: BAP025, colony-stimulating factor-1, CSF-1, Csfm, M-CSF) | |
Results | Reference |
1 | J:29130 Hofstetter W, Wetterwald A, Cecchini MG, Mueller C, Felix R, Detection of transcripts and binding sites for colony-stimulating factor-1 during bone development. Bone. 1995 Aug;17(2):145-51 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:299239 Qin X, Jiang Q, Nagano K, Moriishi T, Miyazaki T, Komori H, Ito K, Mark KV, Sakane C, Kaneko H, Komori T, Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts. PLoS Genet. 2020 Nov;16(11):e1009169 |
1* | J:33690 Roth P, Stanley ER, Colony stimulating factor-1 expression is developmentally regulated in the mouse. J Leukoc Biol. 1996 Jun;59(6):817-23 |
Csf1r colony stimulating factor 1 receptor (Synonyms: CD115, CSF-1R, Csfmr, Fim-2, Fim2, Fms, M-CSFR) | |
Results | Reference |
1* | J:264675 Fransen MF, Benonisson H, van Maren WW, Sow HS, Breukel C, Linssen MM, Claassens JWC, Brouwers C, van der Kaa J, Camps M, Kleinovink JW, Vonk KK, van Heiningen S, Klar N, van Beek L, van Harmelen V, Daxinger L, Nandakumar KS, Holmdahl R, Coward C, Lin Q, Hirose S, Salvatori D, van Hall T, van Kooten C, Mastroeni P, Ossendorp F, Verbeek JS, A Restricted Role for FcgammaR in the Regulation of Adaptive Immunity. J Immunol. 2018 Apr 15;200(8):2615-2626 |
1 | J:189052 Hoeffel G, Wang Y, Greter M, See P, Teo P, Malleret B, Leboeuf M, Low D, Oller G, Almeida F, Choy SH, Grisotto M, Renia L, Conway SJ, Stanley ER, Chan JK, Ng LG, Samokhvalov IM, Merad M, Ginhoux F, Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages. J Exp Med. 2012 Jun 4;209(6):1167-81 |
2 | J:340406 Lai Y, Guo Y, Liao C, Mao C, Liu J, Ren C, Yang W, Luo L, Chen W, Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development. Sci Rep. 2023 Sep 13;13(1):15170 |
1 | J:276880 Motch Perrine SM, Wu M, Stephens NB, Kriti D, van Bakel H, Jabs EW, Richtsmeier JT, Mandibular dysmorphology due to abnormal embryonic osteogenesis in FGFR2-related craniosynostosis mice. Dis Model Mech. 2019 May 30;12(5):dmm038513 |
Csf2 colony stimulating factor 2 (granulocyte-macrophage) (Synonyms: Csfgm, Gm-CSf, GMCSF, MGI-IGM) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:44503 Montgomery RA, Dallman MJ, Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny. Cytokine. 1997 Oct;9(10):717-26 |
1* | J:55762 Montgomery RA, Dallman MJ, Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J Immunol. 1991 Jul 15;147(2):554-60 |
Csf3 colony stimulating factor 3 (granulocyte) (Synonyms: Csfg, G-CSF, MGI-IG) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:158984 Shimoji K, Yuasa S, Onizuka T, Hattori F, Tanaka T, Hara M, Ohno Y, Chen H, Egasgira T, Seki T, Yae K, Koshimizu U, Ogawa S, Fukuda K, G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs. Cell Stem Cell. 2010 Mar 5;6(3):227-37 |
Csf3r colony stimulating factor 3 receptor (Synonyms: Cd114, Csfgr, G-CSFR) | |
Results | Reference |
1 | J:158984 Shimoji K, Yuasa S, Onizuka T, Hattori F, Tanaka T, Hara M, Ohno Y, Chen H, Egasgira T, Seki T, Yae K, Koshimizu U, Ogawa S, Fukuda K, G-CSF promotes the proliferation of developing cardiomyocytes in vivo and in derivation from ESCs and iPSCs. Cell Stem Cell. 2010 Mar 5;6(3):227-37 |
Csgalnact1 chondroitin sulfate N-acetylgalactosaminyltransferase 1 (Synonyms: 4732435N03Rik, CSGalNAcT-1) | |
Results | Reference |
1* | J:120970 Sakai K, Kimata K, Sato T, Gotoh M, Narimatsu H, Shinomiya K, Watanabe H, Chondroitin sulfate N-acetylgalactosaminyltransferase-1 plays a critical role in chondroitin sulfate synthesis in cartilage. J Biol Chem. 2007 Feb 9;282(6):4152-61 |
Csgalnact2 chondroitin sulfate N-acetylgalactosaminyltransferase 2 (Synonyms: 4632415D10Rik, Galnact2) | |
Results | Reference |
1* | J:120970 Sakai K, Kimata K, Sato T, Gotoh M, Narimatsu H, Shinomiya K, Watanabe H, Chondroitin sulfate N-acetylgalactosaminyltransferase-1 plays a critical role in chondroitin sulfate synthesis in cartilage. J Biol Chem. 2007 Feb 9;282(6):4152-61 |
Csk c-src tyrosine kinase | |
Results | Reference |
1* | J:91730 Verma-Kurvari S, Parada LF, Identification of tyrosine kinases expressed in the male mouse gubernaculum during development. Dev Dyn. 2004 Aug;230(4):660-5 |
Csn1s1 casein alpha s1 (Synonyms: Csna) | |
Results | Reference |
1 | J:356957 Rogers RL, Van Seuningen I, Gould J, Hertzog PJ, Naylor MJ, Pritchard MA, Transcript profiling of Elf5+/- mammary glands during pregnancy identifies novel targets of Elf5. PLoS One. 2010 Oct 7;5(10):e13150 |
Csn2 casein beta (Synonyms: CSN2, Csnb) | |
Results | Reference |
1 | J:356957 Rogers RL, Van Seuningen I, Gould J, Hertzog PJ, Naylor MJ, Pritchard MA, Transcript profiling of Elf5+/- mammary glands during pregnancy identifies novel targets of Elf5. PLoS One. 2010 Oct 7;5(10):e13150 |
Csnk1a1 casein kinase 1, alpha 1 (Synonyms: 2610208K14Rik, 4632404G05Rik, 5430427P18Rik, CK1a) | |
Results | Reference |
1 | J:353442 Luo X, Zhang D, Zheng J, Liu H, Sun L, Guo H, Wang L, Cui S, Casein kinase 1alpha mediates estradiol secretion via CYP19A1 expression in mouse ovarian granulosa cells. BMC Biol. 2024 Aug 26;22(1):176 |
Csnk1d casein kinase 1, delta (Synonyms: 1200006A05Rik) | |
Results | Reference |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
Csnk1g3 casein kinase 1, gamma 3 (Synonyms: 3300002K07Rik, C330049O21Rik) | |
Results | Reference |
1* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
Csnk2a1 casein kinase 2, alpha 1 polypeptide (Synonyms: CK2, Csnk2a1-rs4) | |
Results | Reference |
1 | J:162581 Huillard E, Ziercher L, Blond O, Wong M, Deloulme JC, Souchelnytskyi S, Baudier J, Cochet C, Buchou T, Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalon. Mol Cell Biol. 2010 Jun;30(11):2737-49 |
2* | J:16996 Mestres P, Boldyreff B, Ebensperger C, Hameister H, Issinger OG, Expression of casein kinase 2 during mouse embryogenesis. Acta Anat (Basel). 1994;149(1):13-20 |
Csnk2b casein kinase 2, beta polypeptide | |
Results | Reference |
1 | J:162581 Huillard E, Ziercher L, Blond O, Wong M, Deloulme JC, Souchelnytskyi S, Baudier J, Cochet C, Buchou T, Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalon. Mol Cell Biol. 2010 Jun;30(11):2737-49 |
2* | J:16996 Mestres P, Boldyreff B, Ebensperger C, Hameister H, Issinger OG, Expression of casein kinase 2 during mouse embryogenesis. Acta Anat (Basel). 1994;149(1):13-20 |
Cspg4 chondroitin sulfate proteoglycan 4 (Synonyms: 4732461B14Rik, AN2, Cspg4a, NG2) | |
Results | Reference |
1 | J:237340 Ben Shoham A, Rot C, Stern T, Krief S, Akiva A, Dadosh T, Sabany H, Lu Y, Kadler KE, Zelzer E, Deposition of collagen type I onto skeletal endothelium reveals a new role for blood vessels in regulating bone morphology. Development. 2016 Nov 01;143(21):3933-3943 |
3 | J:196361 Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnani MG, Messina G, Cossu G, Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory. Dev Cell. 2013 Mar 25;24(6):586-99 |
1 | J:227058 Chen D, Wang X, Liang D, Gordon J, Mittal A, Manley N, Degenhardt K, Astrof S, Fibronectin signals through integrin alpha5beta1 to regulate cardiovascular development in a cell type-specific manner. Dev Biol. 2015 Nov 15;407(2):195-210 |
1 | J:159507 D'Amico G, Korhonen EA, Waltari M, Saharinen P, Laakkonen P, Alitalo K, Loss of endothelial Tie1 receptor impairs lymphatic vessel development-brief report. Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):207-9 |
1 | J:172287 Esteve P, Sandonis A, Cardozo M, Malapeira J, Ibanez C, Crespo I, Marcos S, Gonzalez-Garcia S, Toribio ML, Arribas J, Shimono A, Guerrero I, Bovolenta P, SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis. Nat Neurosci. 2011 May;14(5):562-9 |
1 | J:228882 Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS, Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016 Jan 1;409(1):218-33 |
1* | J:308556 Goss G, Rognoni E, Salameti V, Watt FM, Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair. Front Cell Dev Biol. 2021;9:675080 |
1 | J:185218 Hall-Glenn F, De Young RA, Huang BL, van Handel B, Hofmann JJ, Chen TT, Choi A, Ong JR, Benya PD, Mikkola H, Iruela-Arispe ML, Lyons KM, CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PLoS One. 2012;7(2):e30562 |
1 | J:293063 Hamashima T, Ishii Y, Nguyen LQ, Okuno N, Sang Y, Matsushima T, Kurashige Y, Takebayashi H, Mori H, Fujimori T, Yamamoto S, Sasahara M, Oligodendrogenesis and Myelin Formation in the Forebrain Require Platelet-derived Growth Factor Receptor-alpha. Neuroscience. 2020 Jun 1;436:11-26 |
1* | J:231833 Hashimoto R, Hori K, Owa T, Miyashita S, Dewa K, Masuyama N, Sakai K, Hayase Y, Seto Y, Inoue YU, Inoue T, Ichinohe N, Kawaguchi Y, Akiyama H, Koizumi S, Hoshino M, Origins of oligodendrocytes in the cerebellum, whose development is controlled by the transcription factor, Sox9. Mech Dev. 2016 May;140:25-40 |
1 | J:162581 Huillard E, Ziercher L, Blond O, Wong M, Deloulme JC, Souchelnytskyi S, Baudier J, Cochet C, Buchou T, Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalon. Mol Cell Biol. 2010 Jun;30(11):2737-49 |
1 | J:239651 Hurtado R, Zewdu R, Mtui J, Liang C, Aho R, Kurylo C, Selleri L, Herzlinger D, Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning. Development. 2015 Aug 01;142(15):2653-64 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:269506 Minocha S, Valloton D, Brunet I, Eichmann A, Hornung JP, Lebrand C, NG2 glia are required for vessel network formation during embryonic development. Elife. 2015 Dec 10;4:e09102 |
1 | J:329397 Nadeem T, Bommareddy A, Bolarinwa L, Cuervo H, Pericyte dynamics in the mouse germinal matrix angiogenesis. FASEB J. 2022 Jun;36(6):e22339 |
1 | J:149138 Norrmen C, Ivanov KI, Cheng J, Zangger N, Delorenzi M, Jaquet M, Miura N, Puolakkainen P, Horsley V, Hu J, Augustin HG, Yla-Herttuala S, Alitalo K, Petrova TV, FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1. J Cell Biol. 2009 May 4;185(3):439-57 |
1 | J:292237 Roostalu U, Aldeiri B, Albertini A, Humphreys N, Simonsen-Jackson M, Wong JKF, Cossu G, Distinct Cellular Mechanisms Underlie Smooth Muscle Turnover in Vascular Development and Repair. Circ Res. 2018 Jan 19;122(2):267-281 |
1 | J:228291 Shinmyo Y, Asrafuzzaman Riyadh M, Ahmed G, Bin Naser I, Hossain M, Takebayashi H, Kawasaki H, Ohta K, Tanaka H, Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex. Nat Commun. 2015;6:10232 |
1 | J:84301 Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M, The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 2003 Jul 1;17(13):1677-89 |
1 | J:116148 Stolt CC, Schlierf A, Lommes P, Hillgartner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M, SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell. 2006 Nov;11(5):697-709 |
1 | J:135133 Sugimori M, Nagao M, Bertrand N, Parras CM, Guillemot F, Nakafuku M, Combinatorial actions of patterning and HLH transcription factors in the spatiotemporal control of neurogenesis and gliogenesis in the developing spinal cord. Development. 2007 Apr;134(8):1617-29 |
1 | J:208012 Zhang B, Xiao W, Qiu H, Zhang F, Moniz HA, Jaworski A, Condac E, Gutierrez-Sanchez G, Heiss C, Clugston RD, Azadi P, Greer JJ, Bergmann C, Moremen KW, Li D, Linhardt RJ, Esko JD, Wang L, Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia. J Clin Invest. 2014 Jan 2;124(1):209-21 |
Csrp1 cysteine and glycine-rich protein 1 (Synonyms: CRP1) | |
Results | Reference |
1 | J:53325 Henderson JR, Macalma T, Brown D, Richardson JA, Olson EN, Beckerle MC, The LIM protein, CRP1, is a smooth muscle marker. Dev Dyn. 1999 Mar;214(3):229-38 |
Csrp2 cysteine and glycine-rich protein 2 (Synonyms: Crp2, SmLim) | |
Results | Reference |
1 | J:73721 Henderson JR, Brown D, Richardson JA, Olson EN, Beckerle MC, Expression of the gene encoding the LIM protein CRP2: a developmental profile. J Histochem Cytochem. 2002 Jan;50(1):107-11 |
1* | J:32734 Jain MK, Fujita KP, Hsieh CM, Endege WO, Sibinga NE, Yet SF, Kashiki S, Lee WS, Perrella MA, Haber E, Lee ME, Molecular cloning and characterization of SmLIM, a developmentally regulated LIM protein preferentially expressed in aortic smooth muscle cells. J Biol Chem. 1996 Apr 26;271(17):10194-9 |
Cst3 cystatin C (Synonyms: CysC) | |
Results | Reference |
2* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:274409 Masuda T, Sankowski R, Staszewski O, Bottcher C, Amann L, Sagar, Scheiwe C, Nessler S, Kunz P, van Loo G, Coenen VA, Reinacher PC, Michel A, Sure U, Gold R, Grun D, Priller J, Stadelmann C, Prinz M, Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution. Nature. 2019 Feb;566(7744):388-392 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Cst9 cystatin 9 (Synonyms: cresp, M12, testatin) | |
Results | Reference |
1* | J:87821 Olesen C, Moller M, Byskov AG, Tesmin transcription is regulated differently during male and female meiosis. Mol Reprod Dev. 2004 Jan;67(1):116-26 |
1 | J:356085 Wang J, Tian GG, Zheng Z, Li B, Xing Q, Wu J, Comprehensive Transcriptomic Analysis of Mouse Gonadal Development Involving Sexual Differentiation, Meiosis and Gametogenesis. Biol Proced Online. 2019;21:20 |
Cstb cystatin B (Synonyms: Stfb) | |
Results | Reference |
2 | J:294878 Di Matteo F, Pipicelli F, Kyrousi C, Tovecci I, Penna E, Crispino M, Chambery A, Russo R, Ayo-Martin AC, Giordano M, Hoffmann A, Ciusani E, Canafoglia L, Gotz M, Di Giaimo R, Cappello S, Cystatin B is essential for proliferation and interneuron migration in individuals with EPM1 epilepsy. EMBO Mol Med. 2020 Jun 8;12(6):e11419 |
Ctcf CCCTC-binding factor | |
Results | Reference |
1 | J:291604 Li J, Zhang T, Ramakrishnan A, Fritzsch B, Xu J, Wong EYM, Loh YE, Ding J, Shen L, Xu PX, Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium. Nucleic Acids Res. 2020 Apr 6;48(6):2880-2896 |
1 | J:206929 Watson LA, Wang X, Elbert A, Kernohan KD, Galjart N, Berube NG, Dual Effect of CTCF Loss on Neuroprogenitor Differentiation and Survival. J Neurosci. 2014 Feb 19;34(8):2860-70 |
Ctdsp2 CTD small phosphatase 2 (Synonyms: D10Ertd73e, OS4, SCP2) | |
Results | Reference |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
Ctf1 cardiotrophin 1 (Synonyms: CT-1) | |
Results | Reference |
1 | J:105646 Oberle S, Schober A, Meyer V, Holtmann B, Henderson C, Sendtner M, Unsicker K, Loss of leukemia inhibitory factor receptor beta or cardiotrophin-1 causes similar deficits in preganglionic sympathetic neurons and adrenal medulla. J Neurosci. 2006 Feb 8;26(6):1823-32 |
1 | J:314320 Wang H, Kane AW, Lee C, Ahn S, Gli3 repressor controls cell fates and cell adhesion for proper establishment of neurogenic niche. Cell Rep. 2014 Aug 21;8(4):1093-104 |
Cthrc1 collagen triple helix repeat containing 1 (Synonyms: 1110014B07Rik) | |
Results | Reference |
1 | J:226941 Akerberg BN, Sarangam ML, Stankunas K, Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Dev Biol. 2015 Nov 1;407(1):158-72 |
3 | J:143940 Kimura H, Kwan KM, Zhang Z, Deng JM, Darnay BG, Behringer RR, Nakamura T, de Crombrugghe B, Akiyama H, Cthrc1 is a positive regulator of osteoblastic bone formation. PLoS One. 2008;3(9):e3174 |
1 | J:159810 Leclair RJ, Wang Q, Benson MA, Prudovsky I, Lindner V, Intracellular localization of Cthrc1 characterizes differentiated smooth muscle. Arterioscler Thromb Vasc Biol. 2008 Jul;28(7):1332-8 |
Ctnna1 catenin alpha 1 (Synonyms: 2010010M04Rik, alpha E catenin, alpha(E)-catenin, catenin (cadherin associated protein), alpha 1, Catna1) | |
Results | Reference |
1* | J:48097 Cifuentes-Diaz C, Goudou D, Mege RM, Velasco E, Nicolet M, Herrenknecht K, Rubin L, Rieger F, Distinct location and prevalence of alpha-, beta-catenins and gamma-catenin/plakoglobin in developing and denervated skeletal muscle. Cell Adhes Commun. 1998 Mar;5(2):161-76 |
2 | J:294113 Lough KJ, Byrd KM, Descovich CP, Spitzer DC, Bergman AJ, Beaudoin GM 3rd, Reichardt LF, Williams SE, Telophase correction refines division orientation in stratified epithelia. Elife. 2019 Dec 13;8:e49249 |
1 | J:258447 Maddala R, Rao PV, Switching of alpha-Catenin From Epithelial to Neuronal Type During Lens Epithelial Cell Differentiation. Invest Ophthalmol Vis Sci. 2017 Jul 1;58(9):3445-3455 |
2 | J:124218 Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan YN, Rakic P, Sestan N, Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci. 2007 Jul;10(7):819-27 |
1 | J:206876 Song JY, Park R, Kim JY, Hughes L, Lu L, Kim S, Johnson RL, Cho SH, Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev Biol. 2014 Feb 15;386(2):281-90 |
2 | J:106946 Stocker AM, Chenn A, Differential expression of alpha-E-catenin and alpha-N-catenin in the developing cerebral cortex. Brain Res. 2006 Feb 16;1073-1074:151-8 |
Ctnna2 catenin alpha 2 (Synonyms: alpha N-catenin, alpha(N)-catenin, Catna, Catna2, chp) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
1* | J:114661 Lyu YL, Lin CP, Azarova AM, Cai L, Wang JC, Liu LF, Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Mol Cell Biol. 2006 Nov;26(21):7929-41 |
1 | J:258447 Maddala R, Rao PV, Switching of alpha-Catenin From Epithelial to Neuronal Type During Lens Epithelial Cell Differentiation. Invest Ophthalmol Vis Sci. 2017 Jul 1;58(9):3445-3455 |
2 | J:106946 Stocker AM, Chenn A, Differential expression of alpha-E-catenin and alpha-N-catenin in the developing cerebral cortex. Brain Res. 2006 Feb 16;1073-1074:151-8 |
1* | J:18004 Uchida N, Shimamura K, Miyatani S, Copeland NG, Gilbert DJ, Jenkins NA, Takeichi M, Mouse alpha N-catenin: two isoforms, specific expression in the nervous system, and chromosomal localization of the gene. Dev Biol. 1994 May;163(1):75-85 |
Ctnnb1 catenin beta 1 (Synonyms: beta catenin, beta-catenin, Bfc, catenin (cadherin associated protein), beta 1, Catnb) | |
Results | Reference |
2 | J:239479 Arora H, Boulberdaa M, Qureshi R, Bitirim V, Messadeq N, Dolle P, Nebigil CG, Prokineticin receptor 1 is required for mesenchymal-epithelial transition in kidney development. FASEB J. 2016 Aug;30(8):2733-40 |
1 | J:196665 Arvanitis DN, Behar A, Tryoen-Toth P, Bush JO, Jungas T, Vitale N, Davy A, Ephrin B1 maintains apical adhesion of neural progenitors. Development. 2013 May;140(10):2082-92 |
1 | J:337598 Au TYK, Yip RKH, Wynn SL, Tan TY, Fu A, Geng YH, Szeto IYY, Niu B, Yip KY, Cheung MCH, Lovell-Badge R, Cheah KSE, Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog-Wnt signaling, causing campomelia. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2208623119 |
1 | J:212241 Boutin C, Labedan P, Dimidschstein J, Richard F, Cremer H, Andre P, Yang Y, Montcouquiol M, Goffinet AM, Tissir F, A dual role for planar cell polarity genes in ciliated cells. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):E3129-38 |
1 | J:127546 Brinkmeier ML, Potok MA, Davis SW, Camper SA, TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors. Dev Biol. 2007 Nov 15;311(2):396-407 |
2* | J:262663 Burke ZD, Reed KR, Yeh SW, Meniel V, Sansom OJ, Clarke AR, Tosh D, Spatiotemporal regulation of liver development by the Wnt/beta-catenin pathway. Sci Rep. 2018 Feb 9;8(1):2735 |
1 | J:192176 Casanova JC, Travisano S, de la Pompa JL, Epithelial-to-mesenchymal transition in epicardium is independent of snail1. Genesis. 2013 Jan;51(1):32-40 |
1 | J:134687 Chang H, Gao F, Guillou F, Taketo MM, Huff V, Behringer RR, Wt1 negatively regulates {beta}-catenin signaling during testis development. Development. 2008 May;135(10):1875-85 |
2* | J:248190 Chen K, Quan H, Chen G, Xiao D, Spatio-temporal expression patterns of Wnt signaling pathway during the development of temporomandibular condylar cartilage. Gene Expr Patterns. 2017 Nov;25-26:149-158 |
1* | J:77897 Chenn A, Walsh CA, Regulation of cerebral cortical size by control of cell cycle exit in neural precursors. Science. 2002 Jul 19;297(5580):365-9 |
1* | J:48097 Cifuentes-Diaz C, Goudou D, Mege RM, Velasco E, Nicolet M, Herrenknecht K, Rubin L, Rieger F, Distinct location and prevalence of alpha-, beta-catenins and gamma-catenin/plakoglobin in developing and denervated skeletal muscle. Cell Adhes Commun. 1998 Mar;5(2):161-76 |
1 | J:217500 Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D, Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60 |
1 | J:98427 Day TF, Guo X, Garrett-Beal L, Yang Y, Wnt/beta-Catenin Signaling in Mesenchymal Progenitors Controls Osteoblast and Chondrocyte Differentiation during Vertebrate Skeletogenesis. Dev Cell. 2005 May;8(5):739-50 |
1 | J:220324 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C, Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 1;142(5):871-82 |
1 | J:198427 Dudok JJ, Sanz AS, Lundvig DM, Wijnholds J, MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. J Neurosci. 2013 May 8;33(19):8518-27 |
1 | J:176438 Esteve P, Sandonis A, Ibanez C, Shimono A, Guerrero I, Bovolenta P, Secreted frizzled-related proteins are required for Wnt/{beta}-catenin signalling activation in the vertebrate optic cup. Development. 2011 Oct;138(19):4179-84 |
1* | J:47740 Fausser JL, Schlepp O, Aberdam D, Meneguzzi G, Ruch JV, Lesot H, Localization of antigens associated with adherens junctions, desmosomes, and hemidesmosomes during murine molar morphogenesis. Differentiation. 1998 May;63(1):1-11 |
1 | J:163382 Foronjy R, Imai K, Shiomi T, Mercer B, Sklepkiewicz P, Thankachen J, Bodine P, D'Armiento J, The divergent roles of secreted frizzled related protein-1 (SFRP1) in lung morphogenesis and emphysema. Am J Pathol. 2010 Aug;177(2):598-607 |
1 | J:206763 Gan Q, Lee A, Suzuki R, Yamagami T, Stokes A, Nguyen BC, Pleasure D, Wang J, Chen HW, Zhou CJ, Pax6 mediates ss-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells. Stem Cells. 2014 Jan;32(1):45-58 |
1 | J:356109 Ge W, Tan SJ, Wang SH, Li L, Sun XF, Shen W, Wang X, Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development. Theranostics. 2020;10(17):7581-7598 |
1* | J:260471 Gerhardt B, Leesman L, Burra K, Snowball J, Rosenzweig R, Guzman N, Ambalavanan M, Sinner D, Notum attenuates Wnt/beta-catenin signaling to promote tracheal cartilage patterning. Dev Biol. 2018 Apr 1;436(1):14-27 |
1 | J:167212 Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ, Subtypes of medulloblastoma have distinct developmental origins. Nature. 2010 Dec 23;468(7327):1095-9 |
1 | J:349032 Gobel C, Schoof M, Holdhof D, Spohn M, Schuller U, SMARCA4 Loss and Mutated beta-Catenin Induce Proliferative Lesions in the Murine Embryonic Cerebellum. J Neurosci. 2024 Apr 10;44(15) |
1 | J:199943 Golovchenko S, Hattori T, Hartmann C, Gebhardt M, Gebhard S, Hess A, Pausch F, Schlund B, von der Mark K, Deletion of beta catenin in hypertrophic growth plate chondrocytes impairs trabecular bone formation. Bone. 2013 Jul;55(1):102-12 |
1* | J:95254 Grove M, Demyanenko G, Echarri A, Zipfel PA, Quiroz ME, Rodriguiz RM, Playford M, Martensen SA, Robinson MR, Wetsel WC, Maness PF, Pendergast AM, ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory. Mol Cell Biol. 2004 Dec;24(24):10905-22 |
1 | J:180109 Guntur AR, Rosen CJ, Naski MC, N-cadherin adherens junctions mediate osteogenesis through PI3K signaling. Bone. 2012 Jan;50(1):54-62 |
1 | J:222425 Harada M, Omori A, Nakahara C, Nakagata N, Akita K, Yamada G, Tissue-specific roles of FGF signaling in external genitalia development. Dev Dyn. 2015 Jun;244(6):759-73 |
1 | J:197815 Hashimoto S, Chen H, Que J, Brockway BL, Drake JA, Snyder JC, Randell SH, Stripp BR, beta-Catenin-SOX2 signaling regulates the fate of developing airway epithelium. J Cell Sci. 2012 Feb 15;125(Pt 4):932-42 |
1 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:237341 Houben A, Kostanova-Poliakova D, Weissenbock M, Graf J, Teufel S, von der Mark K, Hartmann C, beta-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis. Development. 2016 Oct 15;143(20):3826-3838 |
1 | J:94274 Hu H, Hilton MJ, Tu X, Yu K, Ornitz DM, Long F, Sequential roles of Hedgehog and Wnt signaling in osteoblast development. Development. 2005 Jan;132(1):49-60 |
1* | J:283394 Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S, Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162 |
1* | J:280430 Janeckova E, Feng J, Li J, Rodriguez G, Chai Y, Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development. PLoS One. 2019;14(10):e0223879 |
1 | J:334107 Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J, Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice. Hum Mol Genet. 2022 Oct 10;31(20):3504-3520 |
1 | J:324237 Kajimoto M, Suzuki K, Ueda Y, Fujimoto K, Takeo T, Nakagata N, Hyuga T, Isono K, Yamada G, Androgen/Wnt/beta-catenin signal axis augments cell proliferation of the mouse erectile tissue, corpus cavernosum. Congenit Anom (Kyoto). 2022 May;62(3):123-133 |
1 | J:294228 Kalailingam P, Wang KQ, Toh XR, Nguyen TQ, Chandrakanthan M, Hasan Z, Habib C, Schif A, Radio FC, Dallapiccola B, Weiss K, Nguyen LN, Deficiency of MFSD7c results in microcephaly-associated vasculopathy in Fowler syndrome. J Clin Invest. 2020 Aug 3;130(8):4081-4093 |
1* | J:266596 Kersbergen A, Best SA, Dworkin S, Ah-Cann C, de Vries ME, Asselin-Labat ML, Ritchie ME, Jane SM, Sutherland KD, Lung morphogenesis is orchestrated through Grainyhead-like 2 (Grhl2) transcriptional programs. Dev Biol. 2018 Nov 1;443(1):1-9 |
1 | J:138575 Kim AC, Reuter AL, Zubair M, Else T, Serecky K, Bingham NC, Lavery GG, Parker KL, Hammer GD, Targeted disruption of beta-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex. Development. 2008 Aug;135(15):2593-602 |
1* | J:117138 Kimura T, Nakamura T, Murayama K, Umehara H, Yamano N, Watanabe S, Taketo MM, Nakano T, The stabilization of beta-catenin leads to impaired primordial germ cell development via aberrant cell cycle progression. Dev Biol. 2006 Dec 15;300(2):545-53 |
1 | J:266265 Kishimoto K, Tamura M, Nishita M, Minami Y, Yamaoka A, Abe T, Shigeta M, Morimoto M, Synchronized mesenchymal cell polarization and differentiation shape the formation of the murine trachea and esophagus. Nat Commun. 2018 Jul 19;9(1):2816 |
1* | J:99710 Kudo C, Ajioka I, Hirata Y, Nakajima K, Expression profiles of EphA3 at both the RNA and protein level in the developing mammalian forebrain. J Comp Neurol. 2005 Jul 4;487(3):255-69 |
2* | J:316578 Lade A, Ranganathan S, Luo J, Monga SP, Calpain induces N-terminal truncation of beta-catenin in normal murine liver development: diagnostic implications in hepatoblastomas. J Biol Chem. 2012 Jun 29;287(27):22789-98 |
1 | J:254235 Lanctot AA, Guo Y, Le Y, Edens BM, Nowakowski RS, Feng Y, Loss of Brap Results in Premature G1/S Phase Transition and Impeded Neural Progenitor Differentiation. Cell Rep. 2017 Aug 1;20(5):1148-1160 |
1 | J:317151 Lavado A, Gangwar R, Pare J, Wan S, Fan Y, Cao X, YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development. Dev Biol. 2021 Dec;480:39-49 |
1 | J:199510 Lee J, Andreeva A, Sipe CW, Liu L, Cheng A, Lu X, PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium. Curr Biol. 2012 Jun 5;22(11):956-66 |
1 | J:174742 Lehtinen MK, Zappaterra MW, Chen X, Yang YJ, Hill AD, Lun M, Maynard T, Gonzalez D, Kim S, Ye P, D'Ercole AJ, Wong ET, LaMantia AS, Walsh CA, The cerebrospinal fluid provides a proliferative niche for neural progenitor cells. Neuron. 2011 Mar 10;69(5):893-905 |
1 | J:190580 Lei Z, Maeda T, Tamura A, Nakamura T, Yamazaki Y, Shiratori H, Yashiro K, Tsukita S, Hamada H, EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins. Dev Biol. 2012 Nov 15;371(2):136-45 |
1 | J:261049 Leone DP, Srinivasan K, Brakebusch C, McConnell SK, The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain. Dev Neurobiol. 2010 Aug;70(9):659-78 |
1 | J:189074 Li ZJ, Nieuwenhuis E, Nien W, Zhang X, Zhang J, Puviindran V, Wainwright BJ, Kim PC, Hui CC, Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis. Development. 2012 Nov;139(22):4152-61 |
2 | J:277670 Liu J, Zhou Y, Liu Y, Li L, Chen Y, Liu Y, Feng Y, Yosypiv IV, Song R, Peng H, (Pro)renin receptor regulates lung development via the Wnt/beta-catenin signaling pathway. Am J Physiol Lung Cell Mol Physiol. 2019 Aug 1;317(2):L202-L211 |
1 | J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134 |
1* | J:175083 Lorenz A, Deutschmann M, Ahlfeld J, Prix C, Koch A, Smits R, Fodde R, Kretzschmar HA, Schuller U, Severe alterations of cerebellar cortical development after constitutive activation of wnt signaling in granule neuron precursors. Mol Cell Biol. 2011 Aug;31(16):3326-38 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1 | J:156474 Maes C, Goossens S, Bartunkova S, Drogat B, Coenegrachts L, Stockmans I, Moermans K, Nyabi O, Haigh K, Naessens M, Haenebalcke L, Tuckermann JP, Tjwa M, Carmeliet P, Mandic V, David JP, Behrens A, Nagy A, Carmeliet G, Haigh JJ, Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones. EMBO J. 2010 Jan 20;29(2):424-41 |
1 | J:255932 Mario Gonzalez-Meljem J, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Neda Mousavy-Gharavy S, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Pedro Martinez-Barbera J, Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. Nat Commun. 2017 Nov 28;8(1):1819 |
1 | J:235675 Martinez-Garay I, Gil-Sanz C, Franco SJ, Espinosa A, Molnar Z, Mueller U, Cadherin 2/4 signaling via PTP1B and catenins is crucial for nucleokinesis during radial neuronal migration in the neocortex. Development. 2016 Jun 15;143(12):2121-34 |
1 | J:153980 Matsushita T, Chan YY, Kawanami A, Balmes G, Landreth GE, Murakami S, Extracellular signal-regulated kinase 1 (ERK1) and ERK2 play essential roles in osteoblast differentiation and in supporting osteoclastogenesis. Mol Cell Biol. 2009 Nov;29(21):5843-57 |
1 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
1 | J:149225 Miclea RL, Karperien M, Bosch CA, van der Horst G, van der Valk MA, Kobayashi T, Kronenberg HM, Rawadi G, Akcakaya P, Lowik CW, Fodde R, Wit JM, Robanus-Maandag EC, Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors. BMC Dev Biol. 2009;9:26 |
1 | J:85946 Mucenski ML, Wert SE, Nation JM, Loudy DE, Huelsken J, Birchmeier W, Morrisey EE, Whitsett JA, beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis. J Biol Chem. 2003 Oct 10;278(41):40231-8 |
1* | J:77927 Muto S, Aiba A, Saito Y, Nakao K, Nakamura K, Tomita K, Kitamura T, Kurabayashi M, Nagai R, Higashihara E, Harris PC, Katsuki M, Horie S, Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant. Hum Mol Genet. 2002 Jul 15;11(15):1731-42 |
1* | J:297164 Nie X, Zheng J, Cruciger M, Yang P, Mao JJ, mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev Biol. 2020 Nov 1;467(1-2):77-87 |
1* | J:112945 Okubo T, Pevny LH, Hogan BL, Sox2 is required for development of taste bud sensory cells. Genes Dev. 2006 Oct 1;20(19):2654-9 |
1 | J:328944 Olbertova K, Hrckulak D, Kriz V, Jesionek W, Kubovciak J, Esner M, Korinek V, Buchtova M, Role of LGR5-positive mesenchymal cells in craniofacial development. Front Cell Dev Biol. 2022;10:810527 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
2 | J:255488 Premarathne S, Murtaza M, Matigian N, Jolly LA, Wood SA, Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors. Sci Rep. 2017 Aug 14;7(1):8109 |
2 | J:124218 Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan YN, Rakic P, Sestan N, Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci. 2007 Jul;10(7):819-27 |
1 | J:201523 Ray S, Foote HP, Lechler T, beta-Catenin protects the epidermis from mechanical stresses. J Cell Biol. 2013 Jul 8;202(1):45-52 |
1* | J:73292 Ridanpaa M, Fodde R, Kielman M, Dynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structures. Mech Dev. 2001 Dec;109(2):173-81 |
1 | J:202984 Rockich BE, Hrycaj SM, Shih HP, Nagy MS, Ferguson MA, Kopp JL, Sander M, Wellik DM, Spence JR, Sox9 plays multiple roles in the lung epithelium during branching morphogenesis. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4456-64 |
1* | J:310127 Ruan X, Liu G, Zhou J, Chen P, Sun C, Liu W, Wu C, Hou L, Yin B, Qiang B, Shu P, Peng X, Zbed3 Is Indispensable for Wnt Signaling Regulation of Cortical Layers Formation in Developing Brain. Cereb Cortex. 2021 Jul 29;31(9):4078-4091 |
1 | J:181330 Sabine A, Agalarov Y, Maby-El Hajjami H, Jaquet M, Hagerling R, Pollmann C, Bebber D, Pfenniger A, Miura N, Dormond O, Calmes JM, Adams RH, Makinen T, Kiefer F, Kwak BR, Petrova TV, Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation. Dev Cell. 2012 Feb 14;22(2):430-45 |
1 | J:92210 Saotome I, Curto M, McClatchey AI, Ezrin is essential for epithelial organization and villus morphogenesis in the developing intestine. Dev Cell. 2004 Jun;6(6):855-64 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:187998 Shung CY, Ota S, Zhou ZQ, Keene DR, Hurlin PJ, Disruption of a Sox9-beta-catenin circuit by mutant Fgfr3 in thanatophoric dysplasia type II. Hum Mol Genet. 2012 Nov 1;21(21):4628-44 |
1 | J:237499 Sima J, Piao Y, Chen Y, Schlessinger D, Molecular dynamics of Dkk4 modulates Wnt action and regulates meibomian gland development. Development. 2016 Dec 15;143(24):4723-4735 |
1 | J:206876 Song JY, Park R, Kim JY, Hughes L, Lu L, Kim S, Johnson RL, Cho SH, Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev Biol. 2014 Feb 15;386(2):281-90 |
1* | J:229895 Sugiyama Y, Shelley EJ, Yoder BK, Kozmik Z, May-Simera HL, Beales PL, Lovicu FJ, McAvoy JW, Non-essential role for cilia in coordinating precise alignment of lens fibres. Mech Dev. 2016 Feb;139:10-7 |
1 | J:144194 Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72 |
1 | J:213914 Tong CK, Han YG, Shah JK, Obernier K, Guinto CD, Alvarez-Buylla A, Primary cilia are required in a unique subpopulation of neural progenitors. Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):12438-43 |
1* | J:336871 Toonen JA, Ronchetti A, Sidjanin DJ, A Disintegrin and Metalloproteinase10 (ADAM10) Regulates NOTCH Signaling during Early Retinal Development. PLoS One. 2016;11(5):e0156184 |
1 | J:266598 Ustiyan V, Bolte C, Zhang Y, Han L, Xu Y, Yutzey KE, Zorn AM, Kalin TV, Shannon JM, Kalinichenko VV, FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme. Dev Biol. 2018 Nov 1;443(1):50-63 |
1* | J:76569 van Noort M, Meeldijk J, van der Zee R, Destree O, Clevers H, Wnt signaling controls the phosphorylation status of beta-catenin. J Biol Chem. 2002 May 17;277(20):17901-5 |
2 | J:139368 Wang G, Krishnamurthy K, Chiang YW, Dasgupta S, Bieberich E, Regulation of neural progenitor cell motility by ceramide and potential implications for mouse brain development. J Neurochem. 2008 Jul;106(2):718-33 |
1 | J:303486 Wang J, Li T, Wang JL, Xu Z, Meng W, Wu QF, Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions. Cell Rep. 2020 Dec 15;33(11):108495 |
1 | J:153606 Wodarczyk C, Rowe I, Chiaravalli M, Pema M, Qian F, Boletta A, A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus. PLoS One. 2009;4(9):e7137 |
3 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1 | J:362739 Wu Y, Qin K, Xu Y, Rajhans S, Vo T, Lopez KM, Liu J, Nipper MH, Deng J, Yin X, Ramjit LR, Ye Z, Luan Y, Arda HE, Wang P, Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation. Elife. 2024 Jul 25;13 |
1 | J:342339 Xia M, Wu M, Li Y, Liu Y, Jia G, Lou Y, Ma J, Gao Q, Xie M, Chen Y, He Y, Li H, Li W, Varying mechanical forces drive sensory epithelium formation. Sci Adv. 2023 Nov 3;9(44):eadf2664 |
1 | J:338913 Xiang J, Guo J, Zhang S, Wu H, Chen YG, Wang J, Li B, Liu H, A stromal lineage maintains crypt structure and villus homeostasis in the intestinal stem cell niche. BMC Biol. 2023 Aug 8;21(1):169 |
1* | J:146829 Yamada W, Nagao K, Horikoshi K, Fujikura A, Ikeda E, Inagaki Y, Kakitani M, Tomizuka K, Miyazaki H, Suda T, Takubo K, Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun. 2009 Apr 10;381(3):453-8 |
1 | J:141958 Yang SH, Andl T, Grachtchouk V, Wang A, Liu J, Syu LJ, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA, Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta-catenin signaling. Nat Genet. 2008 Sep 1;40(9):1130-5 |
1 | J:264522 Youngblood JL, Coleman TF, Davis SW, Regulation of Pituitary Progenitor Differentiation by beta-Catenin. Endocrinology. 2018 Sep 1;159(9):3287-3305 |
1 | J:125580 Zhang L, Deng M, Kao CW, Kao WW, Xia Y, MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis. Mol Vis. 2003 Nov 3;9:584-93 |
1 | J:299730 Zhang L, Jing H, Li H, Chen W, Luo B, Zhang H, Dong Z, Li L, Su H, Xiong WC, Mei L, Neddylation is critical to cortical development by regulating Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26448-26459 |
1 | J:362758 Zhang L, Li Y, Hu Y, Chen M, Cen C, Chen M, Lin L, Zhou J, Wang M, Cui X, Tang F, Gao F, Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression. FASEB J. 2022 Feb;36(2):e22131 |
1* | J:105879 Zhang TJ, Hoffman BG, Ruiz de Algara T, Helgason CD, SAGE reveals expression of Wnt signalling pathway members during mouse prostate development. Gene Expr Patterns. 2006 Mar;6(3):310-24 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
1 | J:146244 Zuklys S, Gill J, Keller MP, Hauri-Hohl M, Zhanybekova S, Balciunaite G, Na KJ, Jeker LT, Hafen K, Tsukamoto N, Amagai T, Taketo MM, Krenger W, Hollander GA, Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. J Immunol. 2009 Mar 1;182(5):2997-3007 |
Ctnnd1 catenin delta 1 (Synonyms: catenin (cadherin associated protein), delta 1, Catns, Ctnnd, mKIAA0384, P120, p120-catenin) | |
Results | Reference |
1 | J:238285 Adolphe C, Junker JP, Lyubimova A, van Oudenaarden A, Wainwright B, Patched Receptors Sense, Interpret, and Establish an Epidermal Hedgehog Signaling Gradient. J Invest Dermatol. 2017 Jan;137(1):179-186 |
1 | J:346123 Darrigrand JF, Salowka A, Torres-Cano A, Tapia-Rojo R, Zhu T, Garcia-Manyes S, Spagnoli FM, Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner. Dev Cell. 2024 Feb 5;59(3):326-338.e5 |
1 | J:198427 Dudok JJ, Sanz AS, Lundvig DM, Wijnholds J, MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. J Neurosci. 2013 May 8;33(19):8518-27 |
1 | J:180109 Guntur AR, Rosen CJ, Naski MC, N-cadherin adherens junctions mediate osteogenesis through PI3K signaling. Bone. 2012 Jan;50(1):54-62 |
1 | J:219824 Hendley AM, Provost E, Bailey JM, Wang YJ, Cleveland MH, Blake D, Bittman RW, Roeser JC, Maitra A, Reynolds AB, Leach SD, p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas. Dev Biol. 2015 Mar 1;399(1):41-53 |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
1 | J:284168 Nyeng P, Heilmann S, Lof-Ohlin ZM, Pettersson NF, Hermann FM, Reynolds AB, Semb H, p120ctn-Mediated Organ Patterning Precedes and Determines Pancreatic Progenitor Fate. Dev Cell. 2019 Apr 8;49(1):31-47.e9 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
Ctnnd2 catenin delta 2 (Synonyms: catenin (cadherin associated protein), delta 2, Catnd2, neurojugin, Nprap) | |
Results | Reference |
1* | J:43456 Paffenholz R, Franke WW, Identification and localization of a neurally expressed member of the plakoglobin/armadillo multigene family. Differentiation. 1997 Aug;61(5):293-304 |
Cts6 cathepsin 6 (Synonyms: 1600022N02Rik) | |
Results | Reference |
2* | J:63830 Nakajima A, Kataoka K, Takata Y, Huh Nh, Cathepsin-6, a novel cysteine proteinase showing homology with and co-localized expression with cathepsin J/P in the labyrinthine layer of mouse placenta. Biochem J. 2000 Aug 1;349 Pt 3:689-92 |
Ctsb cathepsin B (Synonyms: CB) | |
Results | Reference |
1* | J:315095 Bando Y, Yamamoto M, Sakiyama K, Inoue K, Takizawa S, Owada Y, Iseki S, Kondo H, Amano O, Expression of epidermal fatty acid binding protein (E-FABP) in septoclasts in the growth plate cartilage of mice. J Mol Histol. 2014 Oct;45(5):507-18 |
1 | J:274409 Masuda T, Sankowski R, Staszewski O, Bottcher C, Amann L, Sagar, Scheiwe C, Nessler S, Kunz P, van Loo G, Coenen VA, Reinacher PC, Michel A, Sure U, Gold R, Grun D, Priller J, Stadelmann C, Prinz M, Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution. Nature. 2019 Feb;566(7744):388-392 |
1 | J:326699 Tosun B, Wolff LI, Houben A, Nutt S, Hartmann C, Osteoclasts and Macrophages-Their Role in Bone Marrow Cavity Formation During Mouse Embryonic Development. J Bone Miner Res. 2022 Jun 11; |
Ctsd cathepsin D (Synonyms: CatD, CD) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:150394 Jouret F, Auzanneau C, Debaix H, Wada GH, Pretto C, Marbaix E, Karet FE, Courtoy PJ, Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. J Am Soc Nephrol. 2005 Nov;16(11):3235-46 |
1 | J:311844 Landin MA, Nygard S, Shabestari MG, Babaie E, Reseland JE, Osmundsen H, Mapping the global mRNA transcriptome during development of the murine first molar. Front Genet. 2015;6:47 |
Ctsj cathepsin J (Synonyms: Cat P, CATP, CatRLP, Ctsp, rat gene/Cathepsin L-related protein) | |
Results | Reference |
1* | J:63830 Nakajima A, Kataoka K, Takata Y, Huh Nh, Cathepsin-6, a novel cysteine proteinase showing homology with and co-localized expression with cathepsin J/P in the labyrinthine layer of mouse placenta. Biochem J. 2000 Aug 1;349 Pt 3:689-92 |
Ctsk cathepsin K (Synonyms: catK, Cat K) | |
Results | Reference |
1 | J:237341 Houben A, Kostanova-Poliakova D, Weissenbock M, Graf J, Teufel S, von der Mark K, Hartmann C, beta-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis. Development. 2016 Oct 15;143(20):3826-3838 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:340406 Lai Y, Guo Y, Liao C, Mao C, Liu J, Ren C, Yang W, Luo L, Chen W, Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development. Sci Rep. 2023 Sep 13;13(1):15170 |
2* | J:54282 Li YP, Chen W, Characterization of mouse cathepsin K gene, the gene promoter, and the gene expression. J Bone Miner Res. 1999 Apr;14(4):487-99 |
2* | J:35370 Rantakokko J, Aro HT, Savontaus M, Vuorio E, Mouse cathepsin K: cDNA cloning and predominant expression of the gene in osteoclasts, and in some hypertrophying chondrocytes during mouse development. FEBS Lett. 1996 Sep 16;393(2-3):307-13 |
1 | J:263575 Ruiz P, Martin-Millan M, Gonzalez-Martin MC, Almeida M, Gonzalez-Macias J, Ros MA, CathepsinKCre mediated deletion of betacatenin results in dramatic loss of bone mass by targeting both osteoclasts and osteoblastic cells. Sci Rep. 2016 Nov 2;6:36201 |
1 | J:326699 Tosun B, Wolff LI, Houben A, Nutt S, Hartmann C, Osteoclasts and Macrophages-Their Role in Bone Marrow Cavity Formation During Mouse Embryonic Development. J Bone Miner Res. 2022 Jun 11; |
1 | J:292430 Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, Zhang X, Zhou Y, Yadav PS, Lin J, Wu N, Zhao L, Huang D, Zhou S, Su P, Yang Y, Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ss-catenin. Elife. 2020 Mar 18;9:e52779 |
Ctsl cathepsin L (Synonyms: 1190035F06Rik, Cat L, major excreted protein, MEP) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Ctsq cathepsin Q (Synonyms: 1600010J02Rik) | |
Results | Reference |
1 | J:180242 Dupressoir A, Vernochet C, Harper F, Guegan J, Dessen P, Pierron G, Heidmann T, A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1164-73 |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
1 | J:123073 Kruger I, Vollmer M, Simmons DG, Elsasser HP, Philipsen S, Suske G, Sp1/Sp3 compound heterozygous mice are not viable: Impaired erythropoiesis and severe placental defects. Dev Dyn. 2007 Aug;236(8):2235-44 |
1* | J:260526 Min S, Natale BV, Natale DRC, Temporal and spatial expression of glyceraldehyde 3-phosphate dehydrogenase (Gapdh) in the mouse placenta. Placenta. 2017 Sep;57:170-174 |
1 | J:122534 Simmons DG, Fortier AL, Cross JC, Diverse subtypes and developmental origins of trophoblast giant cells in the mouse placenta. Dev Biol. 2007 Apr 15;304(2):567-78 |
Ctxnd1 cortexin domain containing 1 (Synonyms: C77713, Gm2115) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Cubn cubilin (Synonyms: D2Wsu88e, intrinsic factor-cobalamin receptor) | |
Results | Reference |
1 | J:306107 Niborski LL, Paces-Fessy M, Ricci P, Bourgeois A, Magalhaes P, Kuzma-Kuzniarska M, Lesaulnier C, Reczko M, Declercq E, Zurbig P, Doucet A, Umbhauer M, Cereghini S, Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model. Dis Model Mech. 2021 May 1;14(5):dmm047498 |
Cul3 cullin 3 | |
Results | Reference |
2 | J:306063 Morandell J, Schwarz LA, Basilico B, Tasciyan S, Dimchev G, Nicolas A, Sommer C, Kreuzinger C, Dotter CP, Knaus LS, Dobler Z, Cacci E, Schur FKM, Danzl JG, Novarino G, Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development. Nat Commun. 2021 May 24;12(1):3058 |
Cul4a cullin 4A (Synonyms: 2810470J21Rik) | |
Results | Reference |
1 | J:312461 Yin Y, Zhu L, Li Q, Zhou P, Ma L, Cullin4 E3 Ubiquitin Ligases Regulate Male Gonocyte Migration, Proliferation and Blood-Testis Barrier Homeostasis. Cells. 2021 Oct 13;10(10) |
Cul4b cullin 4B (Synonyms: 2700050M05Rik) | |
Results | Reference |
1 | J:312461 Yin Y, Zhu L, Li Q, Zhou P, Ma L, Cullin4 E3 Ubiquitin Ligases Regulate Male Gonocyte Migration, Proliferation and Blood-Testis Barrier Homeostasis. Cells. 2021 Oct 13;10(10) |
Cul5 cullin 5 (Synonyms: 4921514I20Rik, 8430423K24Rik, C030032G03Rik, C330021I08Rik, VACM-1) | |
Results | Reference |
1 | J:158726 Campos Y, Qiu X, Zanoteli E, Moshiach S, Vergani N, Bongiovanni A, Harris AJ, d'Azzo A, Ozz-E3 ubiquitin ligase targets sarcomeric embryonic myosin heavy chain during muscle development. PLoS One. 2010;5(3):e9866 |
1* | J:257927 Fairchild CL, Hino K, Han JS, Miltner AM, Peinado Allina G, Brown CE, Burns ME, La Torre A, Simo S, RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3):dev155283 |
1* | J:266809 Hino K, Simo S, Cooper JA, Comparative Analysis of cul5 and rbx2 Expression in the Developing and Adult Murine Brain and Their Essentiality During Mouse Embryogenesis. Dev Dyn. 2018 Nov;247(11):1227-1236 |
Cux1 cut-like homeobox 1 (Synonyms: CDP, Cutl1, Cux, Cux-1) | |
Results | Reference |
1 | J:178862 Alfano C, Viola L, Heng JI, Pirozzi M, Clarkson M, Flore G, De Maio A, Schedl A, Guillemot F, Studer M, COUP-TFI promotes radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression. Development. 2011 Nov;138(21):4685-97 |
1* | J:137337 Cadieux C, Harada R, Paquet M, Cote O, Trudel M, Nepveu A, Bouchard M, Polycystic kidneys caused by sustained expression of Cux1 isoform p75. J Biol Chem. 2008 May 16;283(20):13817-24 |
1 | J:324533 Calderon L, Weiss FD, Beagan JA, Oliveira MS, Georgieva R, Wang YF, Carroll TS, Dharmalingam G, Gong W, Tossell K, de Paola V, Whilding C, Ungless MA, Fisher AG, Phillips-Cremins JE, Merkenschlager M, Cohesin-dependence of neuronal gene expression relates to chromatin loop length. Elife. 2022 Apr 26;11:e76539 |
1 | J:228026 Capecchi MR, Pozner A, ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination. Nat Commun. 2015;6:8763 |
1 | J:198427 Dudok JJ, Sanz AS, Lundvig DM, Wijnholds J, MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. J Neurosci. 2013 May 8;33(19):8518-27 |
1 | J:269420 Franz H, Villarreal A, Heidrich S, Videm P, Kilpert F, Mestres I, Calegari F, Backofen R, Manke T, Vogel T, DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex. Nucleic Acids Res. 2019 Jan 10;47(1):168-183 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:101055 Kuo G, Arnaud L, Kronstad-O'Brien P, Cooper JA, Absence of Fyn and Src causes a reeler-like phenotype. J Neurosci. 2005 Sep 14;25(37):8578-86 |
1 | J:297798 Li L, Ghorbani M, Weisz-Hubshman M, Rousseau J, Thiffault I, Schnur RE, Breen C, Oegema R, Weiss MM, Waisfisz Q, Welner S, Kingston H, Hills JA, Boon EM, Basel-Salmon L, Konen O, Goldberg-Stern H, Bazak L, Tzur S, Jin J, Bi X, Bruccoleri M, McWalter K, Cho MT, Scarano M, Schaefer GB, Brooks SS, Hughes SS, van Gassen KLI, van Hagen JM, Pandita TK, Agrawal PB, Campeau PM, Yang XJ, Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability. J Clin Invest. 2020 Mar 2;130(3):1431-1445 |
1 | J:306873 Li L, Jin J, Yang XJ, Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells. iScience. 2019 Oct 25;20:148-167 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:203478 Myshrall TD, Moore SA, Ostendorf AP, Satz JS, Kowalczyk T, Nguyen H, Daza RA, Lau C, Campbell KP, Hevner RF, Dystroglycan on radial glia end feet is required for pial basement membrane integrity and columnar organization of the developing cerebral cortex. J Neuropathol Exp Neurol. 2012 Dec;71(12):1047-63 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1* | J:231073 Oishi K, Aramaki M, Nakajima K, Mutually repressive interaction between Brn1/2 and Rorb contributes to the establishment of neocortical layer 2/3 and layer 4. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3371-6 |
1 | J:269511 Roy A, Skibo J, Kalume F, Ni J, Rankin S, Lu Y, Dobyns WB, Mills GB, Zhao JJ, Baker SJ, Millen KJ, Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy. Elife. 2015 Dec 3;4:e12703 |
1* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
1 | J:215740 Shinohara R, Thumkeo D, Kamijo H, Kaneko N, Sawamoto K, Watanabe K, Takebayashi H, Kiyonari H, Ishizaki T, Furuyashiki T, Narumiya S, A role for mDia, a Rho-regulated actin nucleator, in tangential migration of interneuron precursors. Nat Neurosci. 2012 Mar;15(3):373-80, S1-2 |
1* | J:324710 Stanton-Turcotte D, Hsu K, Moore SA, Yamada M, Fawcett JP, Iulianella A, Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development. J Neurosci. 2022 May 11;42(19):3931-3948 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
1* | J:15712 Valarche I, Tissier-Seta JP, Hirsch MR, Martinez S, Goridis C, Brunet JF, The mouse homeodomain protein Phox2 regulates Ncam promoter activity in concert with Cux/CDP and is a putative determinant of neurotransmitter phenotype. Development. 1993 Nov;119(3):881-96 |
2* | J:34996 Vanden Heuvel GB, Bodmer R, McConnell KR, Nagami GT, Igarashi P, Expression of a cut-related homeobox gene in developing and polycystic mouse kidney. Kidney Int. 1996 Aug;50(2):453-61 |
1 | J:141958 Yang SH, Andl T, Grachtchouk V, Wang A, Liu J, Syu LJ, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA, Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta-catenin signaling. Nat Genet. 2008 Sep 1;40(9):1130-5 |
1 | J:343098 Zhou Z, Pan Y, Zhou S, Wang S, Zhang D, Cao Y, Jiang X, Li J, Zhu L, Zhao L, Gu S, Lin G, Dong Z, Sun HX, Single-cell analysis reveals specific neuronal transition during mouse corticogenesis. Front Cell Dev Biol. 2023;11:1209320 |
Cux2 cut-like homeobox 2 (Synonyms: 1700051K22Rik, Cutl2, Cux-2, Cux2, ENSMUSG00000072641) | |
Results | Reference |
1 | J:178862 Alfano C, Viola L, Heng JI, Pirozzi M, Clarkson M, Flore G, De Maio A, Schedl A, Guillemot F, Studer M, COUP-TFI promotes radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression. Development. 2011 Nov;138(21):4685-97 |
1 | J:178481 Bachy I, Franck MC, Li L, Abdo H, Pattyn A, Ernfors P, The transcription factor Cux2 marks development of an A-delta sublineage of TrkA sensory neurons. Dev Biol. 2011 Dec 1;360(1):77-86 |
1* | J:233823 Capaldo E, Iulianella A, Cux2 serves as a novel lineage marker of granule cell layer neurons from the rhombic lip in mouse and chick embryos. Dev Dyn. 2016 Aug;245(8):881-96 |
1 | J:269420 Franz H, Villarreal A, Heidrich S, Videm P, Kilpert F, Mestres I, Calegari F, Backofen R, Manke T, Vogel T, DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex. Nucleic Acids Res. 2019 Jan 10;47(1):168-183 |
1* | J:166980 Ishikawa T, Gotoh N, Murayama C, Abe T, Iwashita M, Matsuzaki F, Suzuki T, Yamamoto T, IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons. Dev Dyn. 2011 Jan;240(1):96-107 |
1 | J:306873 Li L, Jin J, Yang XJ, Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells. iScience. 2019 Oct 25;20:148-167 |
1 | J:35343 Quaggin SE, Heuvel GBV, Golden K, Bodmer R, Igarashi P, Primary structure, neural-specific expression, and chromosomal localization of Cux-2, a second murine homeobox gene related to Drosophila cut. J Biol Chem. 1996 Sep 13;271(37):22624-34 |
1* | J:143543 Vogel T, Gruss P, Expression of Leukaemia associated transcription factor Af9/Mllt3 in the cerebral cortex of the mouse. Gene Expr Patterns. 2009 Feb;9(2):83-93 |
1 | J:184434 Xiang C, Baubet V, Pal S, Holderbaum L, Tatard V, Jiang P, Davuluri RV, Dahmane N, RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion. Cell Death Differ. 2012 Apr;19(4):692-702 |
1 | J:319651 Yamada M, Clark J, McClelland C, Capaldo E, Ray A, Iulianella A, Cux2 activity defines a subpopulation of perinatal neurogenic progenitors in the hippocampus. Hippocampus. 2015 Feb;25(2):253-67 |
1* | J:157752 Zimmer C, Tiveron MC, Bodmer R, Cremer H, Dynamics of Cux2 expression suggests that an early pool of SVZ precursors is fated to become upper cortical layer neurons. Cereb Cortex. 2004 Dec;14(12):1408-20 |
Cx3cl1 C-X3-C motif chemokine ligand 1 (Synonyms: CX3C, D8Bwg0439e, fractalkine, neurotactin, Scyd1) | |
Results | Reference |
2* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
Cx3cr1 C-X3-C motif chemokine receptor 1 | |
Results | Reference |
1 | J:273194 Anderson SR, Zhang J, Steele MR, Romero CO, Kautzman AG, Schafer DP, Vetter ML, Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia. J Neurosci. 2019 Mar 13;39(11):2025-2040 |
1 | J:302542 Cahill TJ, Sun X, Ravaud C, Villa Del Campo C, Klaourakis K, Lupu IE, Lord AM, Browne C, Jacobsen SEW, Greaves DR, Jackson DG, Cowley SA, James W, Choudhury RP, Vieira JM, Riley PR, Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart. Development. 2021 Feb 3;148(3):dev194563 |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
1* | J:263986 De S, Van Deren D, Peden E, Hockin M, Boulet A, Titen S, Capecchi MR, Two distinct ontogenies confer heterogeneity to mouse brain microglia. Development. 2018 Jul 4;145(13):dev152306 |
1* | J:264675 Fransen MF, Benonisson H, van Maren WW, Sow HS, Breukel C, Linssen MM, Claassens JWC, Brouwers C, van der Kaa J, Camps M, Kleinovink JW, Vonk KK, van Heiningen S, Klar N, van Beek L, van Harmelen V, Daxinger L, Nandakumar KS, Holmdahl R, Coward C, Lin Q, Hirose S, Salvatori D, van Hall T, van Kooten C, Mastroeni P, Ossendorp F, Verbeek JS, A Restricted Role for FcgammaR in the Regulation of Adaptive Immunity. J Immunol. 2018 Apr 15;200(8):2615-2626 |
1* | J:260124 Goldmann T, Wieghofer P, Jordao MJ, Prutek F, Hagemeyer N, Frenzel K, Amann L, Staszewski O, Kierdorf K, Krueger M, Locatelli G, Hochgerner H, Zeiser R, Epelman S, Geissmann F, Priller J, Rossi FM, Bechmann I, Kerschensteiner M, Linnarsson S, Jung S, Prinz M, Origin, fate and dynamics of macrophages at central nervous system interfaces. Nat Immunol. 2016 Jul;17(7):797-805 |
1* | J:333946 Hattori Y, Kato D, Murayama F, Koike S, Asai H, Yamasaki A, Naito Y, Kawaguchi A, Konishi H, Prinz M, Masuda T, Wake H, Miyata T, CD206(+) macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia. Cell Rep. 2023 Feb 7;42(2):112092 |
1 | J:287499 Hattori Y, Naito Y, Tsugawa Y, Nonaka S, Wake H, Nagasawa T, Kawaguchi A, Miyata T, Transient microglial absence assists postmigratory cortical neurons in proper differentiation. Nat Commun. 2020 Apr 2;11(1):1631 |
1 | J:189052 Hoeffel G, Wang Y, Greter M, See P, Teo P, Malleret B, Leboeuf M, Low D, Oller G, Almeida F, Choy SH, Grisotto M, Renia L, Conway SJ, Stanley ER, Chan JK, Ng LG, Samokhvalov IM, Merad M, Ginhoux F, Adult Langerhans cells derive predominantly from embryonic fetal liver monocytes with a minor contribution of yolk sac-derived macrophages. J Exp Med. 2012 Jun 4;209(6):1167-81 |
2 | J:257184 Leid J, Carrelha J, Boukarabila H, Epelman S, Jacobsen SE, Lavine KJ, Primitive Embryonic Macrophages are Required for Coronary Development and Maturation. Circ Res. 2016 May 13;118(10):1498-511 |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1 | J:330324 Masuda T, Amann L, Monaco G, Sankowski R, Staszewski O, Krueger M, Del Gaudio F, He L, Paterson N, Nent E, Fernandez-Klett F, Yamasaki A, Frosch M, Fliegauf M, Bosch LFP, Ulupinar H, Hagemeyer N, Schreiner D, Dorrier C, Tsuda M, Grothe C, Joutel A, Daneman R, Betsholtz C, Lendahl U, Knobeloch KP, Lammermann T, Priller J, Kierdorf K, Prinz M, Specification of CNS macrophage subsets occurs postnatally in defined niches. Nature. 2022 Apr;604(7907):740-748 |
1 | J:354190 Morimoto K, Takahashi R, Takahashi G, Miyajima M, Nakajima K, Maternal immunoglobulins are distributed in the offspring's brain to support the maintenance of cortical interneurons in the postnatal period. Inflamm Regen. 2024 May 15;44(1):24 |
1 | J:260094 Stremmel C, Schuchert R, Wagner F, Thaler R, Weinberger T, Pick R, Mass E, Ishikawa-Ankerhold HC, Margraf A, Hutter S, Vagnozzi R, Klapproth S, Frampton J, Yona S, Scheiermann C, Molkentin JD, Jeschke U, Moser M, Sperandio M, Massberg S, Geissmann F, Schulz C, Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nat Commun. 2018 Jan 8;9(1):75 |
Cxadr coxsackie virus and adenovirus receptor (Synonyms: 2610206D03Rik, CAR, MCAR, MCVADR) | |
Results | Reference |
1 | J:99585 Asher DR, Cerny AM, Weiler SR, Horner JW, Keeler ML, Neptune MA, Jones SN, Bronson RT, Depinho RA, Finberg RW, Coxsackievirus and adenovirus receptor is essential for cardiomyocyte development. Genesis. 2005 Jun;42(2):77-85 |
2* | J:177174 Honda T, Saitoh H, Masuko M, Katagiri-Abe T, Tominaga K, Kozakai I, Kobayashi K, Kumanishi T, Watanabe YG, Odani S, Kuwano R, The coxsackievirus-adenovirus receptor protein as a cell adhesion molecule in the developing mouse brain. Brain Res Mol Brain Res. 2000 Apr 14;77(1):19-28 |
1 | J:83763 Hotta Y, Honda T, Naito M, Kuwano R, Developmental distribution of coxsackie virus and adenovirus receptor localized in the nervous system. Brain Res Dev Brain Res. 2003 Jun 12;143(1):1-13 |
1* | J:100943 Mirza M, Raschperger E, Philipson L, Pettersson RF, Sollerbrant K, The cell surface protein coxsackie- and adenovirus receptor (CAR) directly associates with the Ligand-of-Numb Protein-X2 (LNX2). Exp Cell Res. 2005 Sep 10;309(1):110-20 |
Cxcl1 C-X-C motif chemokine ligand 1 (Synonyms: Fsp, Gro1, KC, KC/GRO-alpha, Mgsa, N51, Scyb1) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Cxcl2 C-X-C motif chemokine ligand 2 (Synonyms: CINC-2a, Gro2, GROb, Mgsa-b, Mip2, MIP-2, MIP-2a, Scyb, Scyb2) | |
Results | Reference |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1 | J:135431 Salminen A, Paananen R, Vuolteenaho R, Metsola J, Ojaniemi M, Autio-Harmainen H, Hallman M, Maternal endotoxin-induced preterm birth in mice: fetal responses in toll-like receptors, collectins, and cytokines. Pediatr Res. 2008 Mar;63(3):280-6 |
Cxcl3 C-X-C motif chemokine ligand 3 (Synonyms: Dcip1) | |
Results | Reference |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
Cxcl5 C-X-C motif chemokine ligand 5 (Synonyms: AMCF-II, Cxcl6, ENA-78, GCP-2, granulocyte chemotactic protein-2, LIX, Scyb5, Scyb6) | |
Results | Reference |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
Cxcl9 C-X-C motif chemokine ligand 9 (Synonyms: CMK, crg-10, Mig, Scyb9) | |
Results | Reference |
1 | J:307825 Fisher AL, Sangkhae V, Balusikova K, Palaskas NJ, Ganz T, Nemeth E, Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy. Nat Commun. 2021 Jun 29;12(1):4026 |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
Cxcl10 C-X-C motif chemokine ligand 10 (Synonyms: C7, CRG-2, gIP-10, Ifi10, INP10, IP-10, IP10, mob-1, Scyb10) | |
Results | Reference |
1 | J:312814 Fernandez Vallone V, Leprovots M, Ribatallada-Soriano D, Gerbier R, Lefort A, Libert F, Vassart G, Garcia MI, LGR5 controls extracellular matrix production by stem cells in the developing intestine. EMBO Rep. 2020 Jul 3;21(7):e49224 |
1 | J:288683 Gacem N, Kavo A, Zerad L, Richard L, Mathis S, Kapur RP, Parisot M, Amiel J, Dufour S, de la Grange P, Pingault V, Vallat JM, Bondurand N, ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. Nat Commun. 2020 Jan 10;11(1):198 |
1 | J:269295 Kang TB, Jeong JS, Yang SH, Kovalenko A, Wallach D, Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3. Cell Death Differ. 2018 Jun;25(6):1107-1117 |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
Cxcl11 chemokine (C-X-C motif) ligand 11 (Synonyms: betaR1, b-R1, H174, IP9, I-TAC, ITAC, Scyb11, SCYB9B) | |
Results | Reference |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1 | J:124878 Sierro F, Biben C, Martinez-Munoz L, Mellado M, Ransohoff RM, Li M, Woehl B, Leung H, Groom J, Batten M, Harvey RP, Martinez-A C, Mackay CR, Mackay F, Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14759-64 |
Cxcl12 C-X-C motif chemokine ligand 12 (Synonyms: PBSF, PBSF/SDF-1, Scyb12, Sdf1, SDF-1, Sdf1a, Sdf1b, TLSF-a, TLSF-b, TPAR1) | |
Results | Reference |
1 | J:225279 Arno B, Grassivaro F, Rossi C, Bergamaschi A, Castiglioni V, Furlan R, Greter M, Favaro R, Comi G, Becher B, Martino G, Muzio L, Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex. Nat Commun. 2014;5:5611 |
1* | J:120667 Bouzin C, Clotman F, Renauld JC, Lemaigre FP, Rousseau GG, The onecut transcription factor hepatocyte nuclear factor-6 controls B lymphopoiesis in fetal liver. J Immunol. 2003 Aug 1;171(3):1297-303 |
1 | J:239363 Cavallero S, Shen H, Yi C, Lien CL, Kumar SR, Sucov HM, CXCL12 Signaling Is Essential for Maturation of the Ventricular Coronary Endothelial Plexus and Establishment of Functional Coronary Circulation. Dev Cell. 2015 May 26;33(4):469-77 |
2* | J:243789 Chang AH, Raftrey BC, D'Amato G, Surya VN, Poduri A, Chen HI, Goldstone AB, Woo J, Fuller GG, Dunn AR, Red-Horse K, DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12-CXCR4 signaling axis. Genes Dev. 2017 Aug 04;31(13):1308-1324 |
2 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1* | J:95331 Daniel D, Rossel M, Seki T, Konig N, Stromal cell-derived factor-1 (SDF-1) expression in embryonic mouse cerebral cortex starts in the intermediate zone close to the pallial-subpallial boundary and extends progressively towards the cortical hem. Gene Expr Patterns. 2005 Feb;5(3):317-22 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1 | J:333567 Gonzalez-Meljem JM, Ivins S, Andoniadou CL, Le Tissier P, Scambler P, Martinez-Barbera JP, An expression and function analysis of the CXCR4/SDF-1 signalling axis during pituitary gland development. PLoS One. 2023;18(2):e0280001 |
1 | J:189818 Haege S, Einer C, Thiele S, Mueller W, Nietzsche S, Lupp A, Mackay F, Schulz S, Stumm R, CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney. PLoS One. 2012;7(8):e42814 |
1 | J:287499 Hattori Y, Naito Y, Tsugawa Y, Nonaka S, Wake H, Nagasawa T, Kawaguchi A, Miyata T, Transient microglial absence assists postmigratory cortical neurons in proper differentiation. Nat Commun. 2020 Apr 2;11(1):1631 |
1 | J:108714 Holt JE, Jackson A, Roman SD, Aitken RJ, Koopman P, McLaughlin EA, CXCR4/SDF1 interaction inhibits the primordial to primary follicle transition in the neonatal mouse ovary. Dev Biol. 2006 May 15;293(2):449-60 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:325446 Lepiemme F, Stoufflet J, Javier-Torrent M, Mazzucchelli G, Silva CG, Nguyen L, Oligodendrocyte precursors guide interneuron migration by unidirectional contact repulsion. Science. 2022 May 20;376(6595):eabn6204 |
1 | J:131835 Li G, Adesnik H, Li J, Long J, Nicoll RA, Rubenstein JL, Pleasure SJ, Regional distribution of cortical interneurons and development of inhibitory tone are regulated by Cxcl12/Cxcr4 signaling. J Neurosci. 2008 Jan 30;28(5):1085-98 |
1 | J:143512 Li G, Kataoka H, Coughlin SR, Pleasure SJ, Identification of a transient subpial neurogenic zone in the developing dentate gyrus and its regulation by Cxcl12 and reelin signaling. Development. 2009 Jan;136(2):327-35 |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1 | J:132219 Lopez-Bendito G, Sanchez-Alcaniz JA, Pla R, Borrell V, Pico E, Valdeolmillos M, Marin O, Chemokine signaling controls intracortical migration and final distribution of GABAergic interneurons. J Neurosci. 2008 Feb 13;28(7):1613-24 |
1 | J:273473 McKey J, Bunce C, Batchvarov IS, Ornitz DM, Capel B, Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5570-5575 |
1 | J:204198 Memi F, Abe P, Cariboni A, MacKay F, Parnavelas JG, Stumm R, CXC chemokine receptor 7 (CXCR7) affects the migration of GnRH neurons by regulating CXCL12 availability. J Neurosci. 2013 Oct 30;33(44):17527-37 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1* | J:34750 Nagasawa T, Hirota S, Tachibana K, Takakura N, Nishikawa S, Kitamura Y, Yoshida N, Kikutani H, Kishimoto T, Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1. Nature. 1996 Aug 15;382(6592):635-8 |
1* | J:203016 Ojeda AF, Munjaal RP, Lwigale PY, Expression of CXCL12 and CXCL14 during eye development in chick and mouse. Gene Expr Patterns. 2013 Dec;13(8):303-10 |
1 | J:241853 Parisot J, Flore G, Bertacchi M, Studer M, COUP-TFI mitotically regulates production and migration of dentate granule cells and modulates hippocampal Cxcr4 expression. Development. 2017 Jun 01;144(11):2045-2058 |
1 | J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34 |
1* | J:138246 Rueda P, Balabanian K, Lagane B, Staropoli I, Chow K, Levoye A, Laguri C, Sadir R, Delaunay T, Izquierdo E, Pablos JL, Lendinez E, Caruz A, Franco D, Baleux F, Lortat-Jacob H, Arenzana-Seisdedos F, The CXCL12gamma chemokine displays unprecedented structural and functional properties that make it a paradigm of chemoattractant proteins. PLoS One. 2008;3(7):e2543 |
1* | J:283877 Sanchez-Alcaniz JA, Haege S, Mueller W, Pla R, Mackay F, Schulz S, Lopez-Bendito G, Stumm R, Marin O, Cxcr7 controls neuronal migration by regulating chemokine responsiveness. Neuron. 2011 Jan 13;69(1):77-90 |
1 | J:163753 Sessa A, Mao CA, Colasante G, Nini A, Klein WH, Broccoli V, Tbr2-positive intermediate (basal) neuronal progenitors safeguard cerebral cortex expansion by controlling amplification of pallial glutamatergic neurons and attraction of subpallial GABAergic interneurons. Genes Dev. 2010 Aug 15;24(16):1816-26 |
1 | J:124878 Sierro F, Biben C, Martinez-Munoz L, Mellado M, Ransohoff RM, Li M, Woehl B, Leung H, Groom J, Batten M, Harvey RP, Martinez-A C, Mackay CR, Mackay F, Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14759-64 |
1 | J:154033 Torres R, Ramirez JC, A chemokine targets the nucleus: Cxcl12-gamma isoform localizes to the nucleolus in adult mouse heart. PLoS One. 2009;4(10):e7570 |
1 | J:304564 Venkataramanappa S, Schutz D, Saaber F, Kumar PA, Abe P, Schulz S, Stumm R, The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS Genet. 2021 Mar;17(3):e1009441 |
1 | J:102920 Vilz TO, Moepps B, Engele J, Molly S, Littman DR, Schilling K, The SDF-1/CXCR4 pathway and the development of the cerebellar system. Eur J Neurosci. 2005 Oct;22(8):1831-9 |
1 | J:204963 Yang S, Edman LC, Sanchez-Alcaniz JA, Fritz N, Bonilla S, Hecht J, Uhlen P, Pleasure SJ, Villaescusa JC, Marin O, Arenas E, Cxcl12/Cxcr4 signaling controls the migration and process orientation of A9-A10 dopaminergic neurons. Development. 2013 Nov;140(22):4554-64 |
3 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Cxcl13 C-X-C motif chemokine ligand 13 (Synonyms: 4631412M08Rik, ANGIE2, BCA-1, BLC, Scyb13) | |
Results | Reference |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
Cxcl14 C-X-C motif chemokine ligand 14 (Synonyms: 1110031L23Rik, 1200006I23Rik, BRAK, Kec, MIP-2g, Scyb14) | |
Results | Reference |
1 | J:202633 Cao Q, Chen H, Deng Z, Yue J, Chen Q, Cao Y, Ning L, Lei X, Duan E, Genetic deletion of Cxcl14 in mice alters uterine NK cells. Biochem Biophys Res Commun. 2013 Jun 14;435(4):664-70 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
3* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1* | J:203016 Ojeda AF, Munjaal RP, Lwigale PY, Expression of CXCL12 and CXCL14 during eye development in chick and mouse. Gene Expr Patterns. 2013 Dec;13(8):303-10 |
1 | J:326535 Petitpre C, Faure L, Uhl P, Fontanet P, Filova I, Pavlinkova G, Adameyko I, Hadjab S, Lallemend F, Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification. Nat Commun. 2022 Jul 5;13(1):3878 |
1 | J:282590 Wei S, Du H, Li Z, Tao G, Xu Z, Song X, Shang Z, Su Z, Chen H, Wen Y, Liu G, You Y, Zhang Z, Yang Z, Transcription factors Sp8 and Sp9 regulate the development of caudal ganglionic eminence-derived cortical interneurons. J Comp Neurol. 2019 Dec 1;527(17):2860-2874 |
2* | J:345228 Zhang Y, Jin Y, Li J, Yan Y, Wang T, Wang X, Li Z, Qin X, CXCL14 as a Key Regulator of Neuronal Development: Insights from Its Receptor and Multi-Omics Analysis. Int J Mol Sci. 2024 Jan 29;25(3) |
Cxcl15 C-X-C motif chemokine ligand 15 (Synonyms: Il8, lungkine, Scyb15, weche) | |
Results | Reference |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
Cxcl16 C-X-C motif chemokine ligand 16 (Synonyms: 0910001K24Rik, Scavenger Receptor, SR-PSOX, SR-PSOX/CXCL16) | |
Results | Reference |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
Cxcl17 C-X-C motif chemokine ligand 17 (Synonyms: MGC:37641) | |
Results | Reference |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
Cxcr3 C-X-C motif chemokine receptor 3 (Synonyms: Cd183, Cmkar3, Cxcr3) | |
Results | Reference |
1* | J:293511 Suttorp CM, Cremers NA, van Rheden R, Regan RF, Helmich P, van Kempen S, Kuijpers-Jagtman AM, Wagener FADTG, Chemokine Signaling during Midline Epithelial Seam Disintegration Facilitates Palatal Fusion. Front Cell Dev Biol. 2017;5:94 |
Cxcr4 C-X-C motif chemokine receptor 4 (Synonyms: b2b220Clo, CD184, Cmkar4, fusin, PB-CKR, Sdf1r) | |
Results | Reference |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
2 | J:189818 Haege S, Einer C, Thiele S, Mueller W, Nietzsche S, Lupp A, Mackay F, Schulz S, Stumm R, CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney. PLoS One. 2012;7(8):e42814 |
1 | J:275470 Hirata K, Kodama S, Nakano Y, Minaki-Nakagawa Y, Aoyama Y, Sakikubo M, Goto T, Yoshida M, Masui T, Yamamoto T, Uemoto S, Kawaguchi Y, Exocrine tissue-driven TFF2 prevents apoptotic cell death of endocrine lineage during pancreas organogenesis. Sci Rep. 2019 Feb 7;9(1):1636 |
1 | J:108714 Holt JE, Jackson A, Roman SD, Aitken RJ, Koopman P, McLaughlin EA, CXCR4/SDF1 interaction inhibits the primordial to primary follicle transition in the neonatal mouse ovary. Dev Biol. 2006 May 15;293(2):449-60 |
1 | J:239364 Ivins S, Chappell J, Vernay B, Suntharalingham J, Martineau A, Mohun TJ, Scambler PJ, The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development. Dev Cell. 2015 May 26;33(4):455-68 |
1* | J:199186 Juuri E, Saito K, Lefebvre S, Michon F, Establishment of crown-root domain borders in mouse incisor. Gene Expr Patterns. 2013 Oct;13(7):255-64 |
1 | J:131835 Li G, Adesnik H, Li J, Long J, Nicoll RA, Rubenstein JL, Pleasure SJ, Regional distribution of cortical interneurons and development of inhibitory tone are regulated by Cxcl12/Cxcr4 signaling. J Neurosci. 2008 Jan 30;28(5):1085-98 |
1 | J:143512 Li G, Kataoka H, Coughlin SR, Pleasure SJ, Identification of a transient subpial neurogenic zone in the developing dentate gyrus and its regulation by Cxcl12 and reelin signaling. Development. 2009 Jan;136(2):327-35 |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1 | J:132219 Lopez-Bendito G, Sanchez-Alcaniz JA, Pla R, Borrell V, Pico E, Valdeolmillos M, Marin O, Chemokine signaling controls intracortical migration and final distribution of GABAergic interneurons. J Neurosci. 2008 Feb 13;28(7):1613-24 |
1 | J:204198 Memi F, Abe P, Cariboni A, MacKay F, Parnavelas JG, Stumm R, CXC chemokine receptor 7 (CXCR7) affects the migration of GnRH neurons by regulating CXCL12 availability. J Neurosci. 2013 Oct 30;33(44):17527-37 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:241853 Parisot J, Flore G, Bertacchi M, Studer M, COUP-TFI mitotically regulates production and migration of dentate granule cells and modulates hippocampal Cxcr4 expression. Development. 2017 Jun 01;144(11):2045-2058 |
1 | J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34 |
2* | J:283877 Sanchez-Alcaniz JA, Haege S, Mueller W, Pla R, Mackay F, Schulz S, Lopez-Bendito G, Stumm R, Marin O, Cxcr7 controls neuronal migration by regulating chemokine responsiveness. Neuron. 2011 Jan 13;69(1):77-90 |
1 | J:215784 Sennett R, Rezza A, Dauber KL, Clavel C, Rendl M, Cxcr4 is transiently expressed in both epithelial and mesenchymal compartments of nascent hair follicles but is not required for follicle formation. Exp Dermatol. 2014 Oct;23(10):748-50 |
1 | J:124878 Sierro F, Biben C, Martinez-Munoz L, Mellado M, Ransohoff RM, Li M, Woehl B, Leung H, Groom J, Batten M, Harvey RP, Martinez-A C, Mackay CR, Mackay F, Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14759-64 |
1 | J:327277 Venkataramanappa S, Saaber F, Abe P, Schutz D, Kumar PA, Stumm R, Cxcr4 and Ackr3 regulate allocation of caudal ganglionic eminence-derived interneurons to superficial cortical layers. Cell Rep. 2022 Aug 2;40(5):111157 |
1 | J:308907 Verheijen N, Suttorp CM, van Rheden REM, Regan RF, Helmich MPAC, Kuijpers-Jagtman AM, Wagener FADTG, CXCL12-CXCR4 Interplay Facilitates Palatal Osteogenesis in Mice. Front Cell Dev Biol. 2020;8:771 |
1 | J:102920 Vilz TO, Moepps B, Engele J, Molly S, Littman DR, Schilling K, The SDF-1/CXCR4 pathway and the development of the cerebellar system. Eur J Neurosci. 2005 Oct;22(8):1831-9 |
1 | J:221658 Vithayathil J, Pucilowska J, Goodnough LH, Atit RP, Landreth GE, Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation. J Neurosci. 2015 Apr 29;35(17):6836-48 |
2 | J:204963 Yang S, Edman LC, Sanchez-Alcaniz JA, Fritz N, Bonilla S, Hecht J, Uhlen P, Pleasure SJ, Villaescusa JC, Marin O, Arenas E, Cxcl12/Cxcr4 signaling controls the migration and process orientation of A9-A10 dopaminergic neurons. Development. 2013 Nov;140(22):4554-64 |
3 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Cyb5d2 cytochrome b5 domain containing 2 (Synonyms: 9330151E16Rik, neuferricin) | |
Results | Reference |
1 | J:282790 Ogawa Y, Sasanuma Y, Shitara S, Koshizuka A, Okada R, Sakuraba H, Oishi K, Abnormal organization during neurodevelopment in a mouse model of Sandhoff disease. Neurosci Res. 2019 Jul 21; |
Cyfip1 cytoplasmic FMR1 interacting protein 1 (Synonyms: E030028J09Rik, l(7)1Rl, l7Rl1, P140SRA-1, pl-1, Shyc, Sra-1) | |
Results | Reference |
1* | J:49729 Koster F, Schinke B, Niemann S, Hermans-Borgmeyer I, Identification of shyc, a novel gene expressed in the murine developing and adult nervous system. Neurosci Lett. 1998 Aug 7;252(1):69-71 |
1* | J:161575 van der Zwaag B, Staal WG, Hochstenbach R, Poot M, Spierenburg HA, de Jonge MV, Verbeek NE, van 't Slot R, van Es MA, Staal FJ, Freitag CM, Buizer-Voskamp JE, Nelen MR, van den Berg LH, van Amstel HK, van Engeland H, Burbach JP, A co-segregating microduplication of chromosome 15q11.2 pinpoints two risk genes for autism spectrum disorder. Am J Med Genet B Neuropsychiatr Genet. 2010 Jun 5;153B(4):960-6 |
1 | J:180006 Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T, NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54 |
Cyfip2 cytoplasmic FMR1 interacting protein 2 (Synonyms: 1500004I01Rik, 6430511D02Rik, mKIAA1168, Pir121) | |
Results | Reference |
1 | J:180006 Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T, NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54 |
1 | J:274819 Zhang Y, Kang H, Lee Y, Kim Y, Lee B, Kim JY, Jin C, Kim S, Kim H, Han K, Smaller Body Size, Early Postnatal Lethality, and Cortical Extracellular Matrix-Related Gene Expression Changes of Cyfip2-Null Embryonic Mice. Front Mol Neurosci. 2018;11:482 |
1* | J:323721 Zhang Y, Kang HR, Han K, Differential cell-type-expression of CYFIP1 and CYFIP2 in the adult mouse hippocampus. Anim Cells Syst (Seoul). 2019;23(6):380-383 |
Cygb cytoglobin (Synonyms: 3110001K20Rik, Staap) | |
Results | Reference |
1* | J:116359 Mammen PP, Shelton JM, Ye Q, Kanatous SB, McGrath AJ, Richardson JA, Garry DJ, Cytoglobin is a stress-responsive hemoprotein expressed in the developing and adult brain. J Histochem Cytochem. 2006 Dec;54(12):1349-61 |
Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 (Synonyms: cytochrome P450 subfamily I, polypeptide 1, P450-1) | |
Results | Reference |
1 | J:142539 Vezina CM, Allgeier SH, Moore RW, Lin TM, Bemis JC, Hardin HA, Gasiewicz TA, Peterson RE, Dioxin causes ventral prostate agenesis by disrupting dorsoventral patterning in developing mouse prostate. Toxicol Sci. 2008 Dec;106(2):488-96 |
Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 | |
Results | Reference |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:142539 Vezina CM, Allgeier SH, Moore RW, Lin TM, Bemis JC, Hardin HA, Gasiewicz TA, Peterson RE, Dioxin causes ventral prostate agenesis by disrupting dorsoventral patterning in developing mouse prostate. Toxicol Sci. 2008 Dec;106(2):488-96 |
Cyp2b19 cytochrome P450, family 2, subfamily b, polypeptide 19 | |
Results | Reference |
1* | J:51300 Keeney DS, Skinner C, Travers JB, Capdevila JH, Nanney LB, King LE Jr, Waterman MR, Differentiating keratinocytes express a novel cytochrome P450 enzyme, CYP2B19, having arachidonate monooxygenase activity. J Biol Chem. 1998 Nov 27;273(48):32071-9 |
Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 (Synonyms: Cyp2e) | |
Results | Reference |
1* | J:188100 Zhang W, Lu D, Dong W, Zhang L, Zhang X, Quan X, Ma C, Lian H, Zhang L, Expression of CYP2E1 increases oxidative stress and induces apoptosis of cardiomyocytes in transgenic mice. FEBS J. 2011 May;278(9):1484-92 |
Cyp2f2 cytochrome P450, family 2, subfamily f, polypeptide 2 (Synonyms: Cyp2f) | |
Results | Reference |
1 | J:188519 Guha A, Vasconcelos M, Cai Y, Yoneda M, Hinds A, Qian J, Li G, Dickel L, Johnson JE, Kimura S, Guo J, McMahon J, McMahon AP, Cardoso WV, Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12592-7 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 (Synonyms: Cyp3a, IIIAm1, Pcn) | |
Results | Reference |
1* | J:317552 Casey SC, Blumberg B, The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver. Mol Endocrinol. 2012 Jun;26(6):916-25 |
Cyp3a16 cytochrome P450, family 3, subfamily a, polypeptide 16 | |
Results | Reference |
1* | J:317552 Casey SC, Blumberg B, The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver. Mol Endocrinol. 2012 Jun;26(6):916-25 |
Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 (Synonyms: cholesterol side chain cleavage, cscc, Cyp11a, D9Ertd411e, P450scc, Scc) | |
Results | Reference |
1* | J:42236 Ikeda Y, Shen WH, Ingraham HA, Parker KL, Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases. Mol Endocrinol. 1994 May;8(5):654-62 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:31107 Keeney DS, Perspectives in steroid hydroxylase gene expression: novel sites of expression during embryonic development. Endocr Res. 1995 Feb-May;21(1-2):103-7 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1 | J:174885 Miyagawa S, Matsumaru D, Murashima A, Omori A, Satoh Y, Haraguchi R, Motoyama J, Iguchi T, Nakagata N, Hui CC, Yamada G, The role of sonic hedgehog-gli2 pathway in the masculinization of external genitalia. Endocrinology. 2011 Jul;152(7):2894-903 |
2 | J:136019 Nishida H, Miyagawa S, Vieux-Rochas M, Morini M, Ogino Y, Suzuki K, Nakagata N, Choi HS, Levi G, Yamada G, Positive regulation of steroidogenic acute regulatory protein gene expression through the interaction between Dlx and GATA-4 for testicular steroidogenesis. Endocrinology. 2008 May;149(5):2090-7 |
1 | J:197599 Pitetti JL, Calvel P, Romero Y, Conne B, Truong V, Papaioannou MD, Schaad O, Docquier M, Herrera PL, Wilhelm D, Nef S, Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice. PLoS Genet. 2013;9(1):e1003160 |
1* | J:62908 Venihaki M, Carrigan A, Dikkes P, Majzoub JA, Circadian rise in maternal glucocorticoid prevents pulmonary dysplasia in fetal mice with adrenal insufficiency. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7336-41 |
1* | J:333014 Wartenberg P, Farkas I, Csillag V, Colledge WH, Hrabovszky E, Boehm U, Sexually Dimorphic Neurosteroid Synthesis Regulates Neuronal Activity in the Murine Brain. J Neurosci. 2021 Nov 3;41(44):9177-9191 |
1 | J:251156 Wen Q, Wang Y, Tang J, Cheng CY, Liu YX, Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development. PLoS One. 2016;11(12):e0167920 |
Cyp11b1 cytochrome P450, family 11, subfamily b, polypeptide 1 (Synonyms: Cyp11b, Cyp11b-1) | |
Results | Reference |
1* | J:210262 Boucher E, Provost PR, Tremblay Y, Ontogeny of adrenal-like glucocorticoid synthesis pathway and of 20alpha-hydroxysteroid dehydrogenase in the mouse lung. BMC Res Notes. 2014;7:119 |
1 | J:315113 Hafner R, Bohnenpoll T, Rudat C, Schultheiss TM, Kispert A, Fgfr2 is required for the expansion of the early adrenocortical primordium. Mol Cell Endocrinol. 2015 Sep 15;413:168-77 |
1* | J:62908 Venihaki M, Carrigan A, Dikkes P, Majzoub JA, Circadian rise in maternal glucocorticoid prevents pulmonary dysplasia in fetal mice with adrenal insufficiency. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7336-41 |
1 | J:320691 Yadav VK, Berger JM, Singh P, Nagarajan P, Karsenty G, Embryonic osteocalcin signaling determines lifelong adrenal steroidogenesis and homeostasis in the mouse. J Clin Invest. 2022 Feb 15;132(4):e153752 |
Cyp11b2 cytochrome P450, family 11, subfamily b, polypeptide 2 (Synonyms: aldosterone synthase, Cyp11b, Cyp11b-2, steroid-11-beta-hydroxylase) | |
Results | Reference |
1 | J:320691 Yadav VK, Berger JM, Singh P, Nagarajan P, Karsenty G, Embryonic osteocalcin signaling determines lifelong adrenal steroidogenesis and homeostasis in the mouse. J Clin Invest. 2022 Feb 15;132(4):e153752 |
Cyp17a1 cytochrome P450, family 17, subfamily a, polypeptide 1 (Synonyms: Cyp17, p450c17, steroid 17-alpha hydroxylase) | |
Results | Reference |
1 | J:147876 Barsoum IB, Bingham NC, Parker KL, Jorgensen JS, Yao HH, Activation of the Hedgehog pathway in the mouse fetal ovary leads to ectopic appearance of fetal Leydig cells and female pseudohermaphroditism. Dev Biol. 2009 May 1;329(1):96-103 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:31107 Keeney DS, Perspectives in steroid hydroxylase gene expression: novel sites of expression during embryonic development. Endocr Res. 1995 Feb-May;21(1-2):103-7 |
1* | J:29760 Keeney DS, Jenkins CM, Waterman MR, Developmentally regulated expression of adrenal 17 alpha-hydroxylase cytochrome P450 in the mouse embryo. Endocrinology. 1995 Nov;136(11):4872-9 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1* | J:21125 Lee CH, Taketo T, Normal onset, but prolonged expression, of Sry gene in the B6.YDOM sex-reversed mouse gonad. Dev Biol. 1994 Oct;165(2):442-52 |
1 | J:237537 Liu C, Rodriguez K, Yao HH, Mapping lineage progression of somatic progenitor cells in the mouse fetal testis. Development. 2016 Oct 15;143(20):3700-3710 |
2 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1 | J:205146 Praktiknjo SD, Llamas B, Scott-Boyer MP, Picard S, Robert F, Langlais D, Haibe-Kains B, Faubert D, Silversides DW, Deschepper CF, Novel effects of chromosome Y on cardiac regulation, chromatin remodeling, and neonatal programming in male mice. Endocrinology. 2013 Dec;154(12):4746-56 |
1* | J:333014 Wartenberg P, Farkas I, Csillag V, Colledge WH, Hrabovszky E, Boehm U, Sexually Dimorphic Neurosteroid Synthesis Regulates Neuronal Activity in the Murine Brain. J Neurosci. 2021 Nov 3;41(44):9177-9191 |
Cyp19a1 cytochrome P450, family 19, subfamily a, polypeptide 1 (Synonyms: Ar, ArKO, aromatase, Cyp19, Int-5, Int5, p450arom) | |
Results | Reference |
1* | J:43805 Abe-Dohmae S, Takagi Y, Harada N, Autonomous expression of aromatase during development of mouse brain is modulated by neurotransmitters. J Steroid Biochem Mol Biol. 1997 Apr;61(3-6):299-306 |
1* | J:21125 Lee CH, Taketo T, Normal onset, but prolonged expression, of Sry gene in the B6.YDOM sex-reversed mouse gonad. Dev Biol. 1994 Oct;165(2):442-52 |
1* | J:333014 Wartenberg P, Farkas I, Csillag V, Colledge WH, Hrabovszky E, Boehm U, Sexually Dimorphic Neurosteroid Synthesis Regulates Neuronal Activity in the Murine Brain. J Neurosci. 2021 Nov 3;41(44):9177-9191 |
Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 (Synonyms: 21-hydroxylase, 21-OH, 21OH, 21OHA, Cyp21, Oh21-1, Oh21-1) | |
Results | Reference |
1* | J:163555 Huang CC, Yao HH, Inactivation of Dicer1 in Steroidogenic factor 1-positive cells reveals tissue-specific requirement for Dicer1 in adrenal, testis, and ovary. BMC Dev Biol. 2010;10:66 |
1 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
Cyp24a1 cytochrome P450, family 24, subfamily a, polypeptide 1 (Synonyms: 24-OHase, 25-hydroxyvitamin D-24-hydroxylase, CP24, Cyp24) | |
Results | Reference |
1* | J:111272 Chau H, El-Maadawy S, McKee MD, Tenenhouse HS, Renal calcification in mice homozygous for the disrupted type IIa Na/Pi cotransporter gene Npt2. J Bone Miner Res. 2003 Apr;18(4):644-57 |
Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 (Synonyms: Cyp26, MGC:13860, P450RA, P450RAI, RAH, retinoic acid hydrolase) | |
Results | Reference |
1* | J:167740 Alfano G, Conte I, Caramico T, Avellino R, Arno B, Pizzo MT, Tanimoto N, Beck SC, Huber G, Dolle P, Seeliger MW, Banfi S, Vax2 regulates retinoic acid distribution and cone opsin expression in the vertebrate eye. Development. 2011 Jan;138(2):261-71 |
1 | J:121381 Hu P, Zhang M, Napoli JL, Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal. Biochim Biophys Acta. 2007 Apr;1770(4):694-705 |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
1* | J:62941 Malpel S, Mendelsohn C, Cardoso WV, Regulation of retinoic acid signaling during lung morphogenesis. Development. 2000 Jul;127(14):3057-67 |
1* | J:134349 Vezina CM, Allgeier SH, Fritz WA, Moore RW, Strerath M, Bushman W, Peterson RE, Retinoic acid induces prostatic bud formation. Dev Dyn. 2008 May;237(5):1321-33 |
Cyp26b1 cytochrome P450, family 26, subfamily b, polypeptide 1 (Synonyms: CP26, P450RAI-2, retinoic acid B1) | |
Results | Reference |
1* | J:73809 Abu-Abed S, MacLean G, Fraulob V, Chambon P, Petkovich M, Dolle P, Differential expression of the retinoic acid-metabolizing enzymes CYP26A1 and CYP26B1 during murine organogenesis. Mech Dev. 2002 Jan;110(1-2):173-7 |
1 | J:179634 Chassot AA, Gregoire EP, Lavery R, Taketo MM, de Rooij DG, Adams IR, Chaboissier MC, RSPO1/beta-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary. PLoS One. 2011;6(10):e25641 |
1* | J:302398 Edelsztein NY, Kashimada K, Schteingart HF, Rey RA, CYP26B1 declines postnatally in Sertoli cells independently of androgen action in the mouse testis. Mol Reprod Dev. 2020 Jan;87(1):66-77 |
1 | J:121381 Hu P, Zhang M, Napoli JL, Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal. Biochim Biophys Acta. 2007 Apr;1770(4):694-705 |
1 | J:256526 Kuerbitz J, Arnett M, Ehrman S, Williams MT, Vorhees CV, Fisher SE, Garratt AN, Muglia LJ, Waclaw RR, Campbell K, Loss of Intercalated Cells (ITCs) in the Mouse Amygdala of Tshz1 Mutants Correlates with Fear, Depression, and Social Interaction Phenotypes. J Neurosci. 2018 Jan 31;38(5):1160-1177 |
1 | J:284900 Larsen R, Proue A, Scott EP, Christiansen M, Nakagawa Y, The Thalamus Regulates Retinoic Acid Signaling and Development of Parvalbumin Interneurons in Postnatal Mouse Prefrontal Cortex. eNeuro. 2019 Jan-Feb;6(1):ENEURO.0018-19.2019 |
1 | J:246806 Li Y, Zhang L, Hu Y, Chen M, Han F, Qin Y, Chen M, Cui X, Duo S, Tang F, Gao F, beta-Catenin directs the transformation of testis Sertoli cells to ovarian granulosa-like cells by inducing Foxl2 expression. J Biol Chem. 2017 Oct 27;292(43):17577-17586 |
1 | J:316129 Login H, Butowt R, Bohm S, Activity-dependent and graded BACE1 expression in the olfactory epithelium is mediated by the retinoic acid metabolizing enzyme CYP26B1. Brain Struct Funct. 2015 Jul;220(4):2143-57 |
1 | J:158526 Naillat F, Prunskaite-Hyyrylainen R, Pietila I, Sormunen R, Jokela T, Shan J, Vainio SJ, Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development. Hum Mol Genet. 2010 Apr 15;19(8):1539-50 |
2 | J:192641 Okano J, Levy C, Lichti U, Sun HW, Yuspa SH, Sakai Y, Morasso MI, Cutaneous retinoic acid levels determine hair follicle development and downgrowth. J Biol Chem. 2012 Nov 16;287(47):39304-15 |
1* | J:134349 Vezina CM, Allgeier SH, Fritz WA, Moore RW, Strerath M, Bushman W, Peterson RE, Retinoic acid induces prostatic bud formation. Dev Dyn. 2008 May;237(5):1321-33 |
Cyp26c1 cytochrome P450, family 26, subfamily c, polypeptide 1 (Synonyms: EG546726) | |
Results | Reference |
1* | J:167740 Alfano G, Conte I, Caramico T, Avellino R, Arno B, Pizzo MT, Tanimoto N, Beck SC, Huber G, Dolle P, Seeliger MW, Banfi S, Vax2 regulates retinoic acid distribution and cone opsin expression in the vertebrate eye. Development. 2011 Jan;138(2):261-71 |
1* | J:85714 Tahayato A, Dolle P, Petkovich M, Cyp26C1 encodes a novel retinoic acid-metabolizing enzyme expressed in the hindbrain, inner ear, first branchial arch and tooth buds during murine development. Gene Expr Patterns. 2003 Aug;3(4):449-54 |
Cyp27b1 cytochrome P450, family 27, subfamily b, polypeptide 1 (Synonyms: 1alpha(OH)ase, 25-hydroxyvitamin D3 1alpha-hydroxylase, 25(OH)D 1alpha-hydroxylase, Cp2b, Cyp1, Cyp27b, Cyp40, P450c1, P450VD1alpha, Pddr, Vdd1, Vddr, VddrI) | |
Results | Reference |
1* | J:111272 Chau H, El-Maadawy S, McKee MD, Tenenhouse HS, Renal calcification in mice homozygous for the disrupted type IIa Na/Pi cotransporter gene Npt2. J Bone Miner Res. 2003 Apr;18(4):644-57 |
Cyria CYFIP related Rac1 interactor A (Synonyms: 2410157M17Rik, D12Ertd553e, Fam49a) | |
Results | Reference |
1* | J:350102 Yu Y, Zuo X, He M, Gao J, Fu Y, Qin C, Meng L, Wang W, Song Y, Cheng Y, Zhou F, Chen G, Zheng X, Wang X, Liang B, Zhu Z, Fu X, Sheng Y, Hao J, Liu Z, Yan H, Mangold E, Ruczinski I, Liu J, Marazita ML, Ludwig KU, Beaty TH, Zhang X, Sun L, Bian Z, Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity. Nat Commun. 2017 Feb 24;8:14364 |
Cys1 cystin 1 (Synonyms: 2900006B19Rik, ck) | |
Results | Reference |
1 | J:125042 Pierreux CE, Poll AV, Kemp CR, Clotman F, Maestro MA, Cordi S, Ferrer J, Leyns L, Rousseau GG, Lemaigre FP, The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. Gastroenterology. 2006 Feb;130(2):532-41 |
2* | J:161877 Tao B, Bu S, Yang Z, Siroky B, Kappes JC, Kispert A, Guay-Woodford LM, Cystin localizes to primary cilia via membrane microdomains and a targeting motif. J Am Soc Nephrol. 2009 Dec;20(12):2570-80 |
Cyth3 cytohesin 3 (Synonyms: cytohesin 3, Grp1, Pscd3) | |
Results | Reference |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
D030025E07Rik RIKEN cDNA D030025E07 gene (Synonyms: Playrr, Plyrr) | |
Results | Reference |
1* | J:330442 Garcia-Padilla C, Dominguez JN, Lodde V, Munk R, Abdelmohsen K, Gorospe M, Jimenez-Sabado V, Ginel A, Hove-Madsen L, Aranega AE, Franco D, Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation. FASEB J. 2022 Jan;36(1):e22051 |
D430004P15Rik Riken cDNA D430004P15 gene | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
D430041D05Rik RIKEN cDNA D430041D05 gene (Synonyms: 9630056G07Rik, G2) | |
Results | Reference |
1* | J:58552 Gawin B, Niederfuhr A, Schumacher N, Hummerich H, Little PF, Gessler M, A 7.5 Mb sequence-ready PAC contig and gene expression map of human chromosome 11p13-p14.1. Genome Res. 1999 Nov;9(11):1074-86 |
D630008O14Rik RIKEN cDNA D630008O14 gene (Synonyms: D630044D05Rik) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
D630024D03Rik RIKEN cDNA D630024D03 gene | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
D630029K05Rik RIKEN cDNA D630029K05 gene | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
D630045J12Rik RIKEN cDNA D630045J12 gene (Synonyms: mKIAA1549) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
D930028M14Rik RIKEN cDNA D930028M14 gene (Synonyms: EG434147) | |
Results | Reference |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
Daam1 dishevelled associated activator of morphogenesis 1 (Synonyms: 1700066F09Rik, 2310028E21Rik) | |
Results | Reference |
1* | J:93596 Kida Y, Shiraishi T, Ogura T, Identification of chick and mouse Daam1 and Daam2 genes and their expression patterns in the central nervous system. Brain Res Dev Brain Res. 2004 Oct 15;153(1):143-50 |
2 | J:167714 Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, Chen H, Haneline LS, Chan RJ, Schwartz RJ, Field LJ, Atkinson SJ, Shou W, Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development. 2011 Jan;138(2):303-15 |
Daam2 dishevelled associated activator of morphogenesis 2 (Synonyms: 2310016D11Rik) | |
Results | Reference |
1 | J:259892 Campbell DP, Chrysostomou E, Doetzlhofer A, Canonical Notch signaling plays an instructive role in auditory supporting cell development. Sci Rep. 2016 Jan 20;6:19484 |
1* | J:93596 Kida Y, Shiraishi T, Ogura T, Identification of chick and mouse Daam1 and Daam2 genes and their expression patterns in the central nervous system. Brain Res Dev Brain Res. 2004 Oct 15;153(1):143-50 |
Dab1 disabled 1 (Synonyms: C630028C02Rik) | |
Results | Reference |
1 | J:109820 Arnaud L, Ballif BA, Forster E, Cooper JA, Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development. Curr Biol. 2003 Jan 8;13(1):9-17 |
1* | J:90089 Ballif BA, Arnaud L, Arthur WT, Guris D, Imamoto A, Cooper JA, Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons. Curr Biol. 2004 Apr 6;14(7):606-10 |
1 | J:126745 Borrell V, Pujadas L, Simo S, Dura D, Sole M, Cooper JA, Del Rio JA, Soriano E, Reelin and mDab1 regulate the development of hippocampal connections. Mol Cell Neurosci. 2007 Oct;36(2):158-73 |
1* | J:138800 De Gasperi R, Gama Sosa MA, Wen PH, Li J, Perez GM, Curran T, Elder GA, Cortical development in the presenilin-1 null mutant mouse fails after splitting of the preplate and is not due to a failure of reelin-dependent signaling. Dev Dyn. 2008 Sep;237(9):2405-14 |
2* | J:265269 Dhananjaya D, Hung KY, Tarn WY, RBM4 Modulates Radial Migration via Alternative Splicing of Dab1 during Cortex Development. Mol Cell Biol. 2018 Jun 15;38(12) |
1* | J:257927 Fairchild CL, Hino K, Han JS, Miltner AM, Peinado Allina G, Brown CE, Burns ME, La Torre A, Simo S, RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3):dev155283 |
1 | J:145031 Feng L, Cooper JA, Dual functions of Dab1 during brain development. Mol Cell Biol. 2009 Jan;29(2):324-32 |
2 | J:174747 Franco SJ, Martinez-Garay I, Gil-Sanz C, Harkins-Perry SR, Muller U, Reelin regulates cadherin function via Dab1/Rap1 to control neuronal migration and lamination in the neocortex. Neuron. 2011 Feb 10;69(3):482-97 |
2* | J:186654 Gao Z, Poon HY, Li L, Li X, Palmesino E, Glubrecht DD, Colwill K, Dutta I, Kania A, Pawson T, Godbout R, Splice-mediated motif switching regulates disabled-1 phosphorylation and SH2 domain interactions. Mol Cell Biol. 2012 Jul;32(14):2794-808 |
1* | J:74239 Herrick TM, Cooper JA, A hypomorphic allele of dab1 reveals regional differences in reelin-Dab1 signaling during brain development. Development. 2002 Feb 1;129(3):787-96 |
1 | J:91679 Herrick TM, Cooper JA, High affinity binding of Dab1 to Reelin receptors promotes normal positioning of upper layer cortical plate neurons. Brain Res Mol Brain Res. 2004 Jul 26;126(2):121-8 |
2 | J:153525 Hurtado-Chong A, Yusta-Boyo MJ, Vergano-Vera E, Bulfone A, de Pablo F, Vicario-Abejon C, IGF-I promotes neuronal migration and positioning in the olfactory bulb and the exit of neuroblasts from the subventricular zone. Eur J Neurosci. 2009 Sep;30(5):742-55 |
1 | J:299731 Kohno T, Ishii K, Hirota Y, Honda T, Makino M, Kawasaki T, Nakajima K, Hattori M, Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner. J Neurosci. 2020 Oct 21;40(43):8248-8261 |
1 | J:101055 Kuo G, Arnaud L, Kronstad-O'Brien P, Cooper JA, Absence of Fyn and Src causes a reeler-like phenotype. J Neurosci. 2005 Sep 14;25(37):8578-86 |
1* | J:91057 Louvi A, Sisodia SS, Grove EA, Presenilin 1 in migration and morphogenesis in the central nervous system. Development. 2004 Jul;131(13):3093-105 |
1* | J:82121 Luque JM, Morante-Oria J, Fairen A, Localization of ApoER2, VLDLR and Dab1 in radial glia: groundwork for a new model of reelin action during cortical development. Brain Res Dev Brain Res. 2003 Feb 16;140(2):195-203 |
1 | J:232899 Moon UY, Park JY, Park R, Cho JY, Hughes LJ, McKenna J 3rd, Goetzl L, Cho SH, Crino PB, Gambello MJ, Kim S, Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex. Cell Rep. 2015 Aug 11;12(6):965-78 |
1 | J:250180 Nakagawa N, Yagi H, Kato K, Takematsu H, Oka S, Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy. Sci Rep. 2015 Jun 10;5:11163 |
1 | J:240398 Ogino H, Hisanaga A, Kohno T, Kondo Y, Okumura K, Kamei T, Sato T, Asahara H, Tsuiji H, Fukata M, Hattori M, Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin. J Neurosci. 2017 Mar 22;37(12):3181-3191 |
1* | J:56295 Ohshima T, Gilmore EC, Longenecker G, Jacobowitz DM, Brady RO, Herrup K, Kulkarni AB, Migration defects of cdk5(-/-) neurons in the developing cerebellum is cell autonomous. J Neurosci. 1999 Jul 15;19(14):6017-26 |
1* | J:120590 Ohshima T, Suzuki H, Morimura T, Ogawa M, Mikoshiba K, Modulation of Reelin signaling by Cyclin-dependent kinase 5. Brain Res. 2007 Apr 6;1140:84-95 |
1 | J:85055 Petrone A, Battaglia F, Wang C, Dusa A, Su J, Zagzag D, Bianchi R, Casaccia-Bonnefil P, Arancio O, Sap J, Receptor protein tyrosine phosphatase alpha is essential for hippocampal neuronal migration and long-term potentiation. EMBO J. 2003 Aug 15;22(16):4121-31 |
4 | J:50400 Rice DS, Sheldon M, D'Arcangelo G, Nakajima K, Goldowitz D, Curran T, Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain. Development. 1998 Sep;125(18):3719-29 |
1 | J:171375 Senturk A, Pfennig S, Weiss A, Burk K, Acker-Palmer A, Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration. Nature. 2011 Apr 21;472(7343):356-60 |
2 | J:77999 Sugitani Y, Nakai S, Minowa O, Nishi M, Jishage K, Kawano H, Mori K, Ogawa M, Noda T, Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. Genes Dev. 2002 Jul 15;16(14):1760-5 |
2 | J:116689 Yamashita N, Uchida Y, Ohshima T, Hirai S, Nakamura F, Taniguchi M, Mikoshiba K, Honnorat J, Kolattukudy P, Thomasset N, Takei K, Takahashi T, Goshima Y, Collapsin response mediator protein 1 mediates reelin signaling in cortical neuronal migration. J Neurosci. 2006 Dec 20;26(51):13357-62 |
1 | J:163165 Yano M, Hayakawa-Yano Y, Mele A, Darnell RB, Nova2 regulates neuronal migration through an RNA switch in disabled-1 signaling. Neuron. 2010 Jun 24;66(6):848-58 |
1 | J:132843 Yip YP, Kronstadt-O'Brien P, Capriotti C, Cooper JA, Yip JW, Migration of sympathetic preganglionic neurons in the spinal cord is regulated by Reelin-dependent Dab1 tyrosine phosphorylation and CrkL. J Comp Neurol. 2007 Jun 1;502(4):635-43 |
Dab2 disabled 2, mitogen-responsive phosphoprotein (Synonyms: 5730435J12Rik, D15Wsu122e, D630005B22Rik, p96) | |
Results | Reference |
1* | J:140134 Cheung KK, Mok SC, Rezaie P, Chan WY, Dynamic expression of Dab2 in the mouse embryonic central nervous system. BMC Dev Biol. 2008;8:76 |
Dab2ip disabled 2 interacting protein (Synonyms: 2310011D08Rik, AIP1, mKIAA1743) | |
Results | Reference |
2 | J:85094 Homayouni R, Magdaleno S, Keshvara L, Rice DS, Curran T, Interaction of Disabled-1 and the GTPase activating protein Dab2IP in mouse brain. Brain Res Mol Brain Res. 2003 Jul 23;115(2):121-9 |
1 | J:191935 Lee GH, Kim SH, Homayouni R, D'Arcangelo G, Dab2ip regulates neuronal migration and neurite outgrowth in the developing neocortex. PLoS One. 2012;7(10):e46592 |
Dach1 dachshund family transcription factor 1 (Synonyms: D6, Dac, E130112M23Rik) | |
Results | Reference |
1 | J:81143 Backman M, Machon O, Van Den Bout CJ, Krauss S, Targeted disruption of mouse Dach1 results in postnatal lethality. Dev Dyn. 2003 Jan;226(1):139-44 |
1* | J:243789 Chang AH, Raftrey BC, D'Amato G, Surya VN, Poduri A, Chen HI, Goldstone AB, Woo J, Fuller GG, Dunn AR, Red-Horse K, DACH1 stimulates shear stress-guided endothelial cell migration and coronary artery growth through the CXCL12-CXCR4 signaling axis. Genes Dev. 2017 Aug 04;31(13):1308-1324 |
2* | J:52628 Davis RJ, Shen W, Heanue TA, Mardon G, Mouse Dach, a homologue of Drosophila dachshund, is expressed in the developing retina, brain and limbs. Dev Genes Evol. 1999 Sep;209(9):526-36 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1 | J:245878 Sharma B, Ho L, Ford GH, Chen HI, Goldstone AB, Woo YJ, Quertermous T, Reversade B, Red-Horse K, Alternative Progenitor Cells Compensate to Rebuild the Coronary Vasculature in Elabela- and Apj-Deficient Hearts. Dev Cell. 2017 Sep 25;42(6):655-666.e3 |
1 | J:338451 Shintani A, Fukai S, Nobusawa R, Taniguchi K, Hatatani T, Nagai H, Sakai T, Yoshimura T, Miyasaka M, Hayasaka H, Dach1 transcription factor regulates the expression of peripheral node addressin and lymphocyte trafficking in lymph nodes. Curr Res Immunol. 2022;3:175-185 |
1 | J:361664 Vitali HE, Kuschel B, Sherpa C, Jones BW, Jacob N, Madiha SA, Elliott S, Dziennik E, Kreun L, Conatser C, Bhetwal BP, Sharma B, Hypoxia regulate developmental coronary angiogenesis potentially through VEGF-R2- and SOX17-mediated signaling. Dev Dyn. 2025 Feb;254(2):174-188 |
Dact1 dishevelled-binding antagonist of beta-catenin 1 (Synonyms: Dapper1, Frd1, Frodo, Frodo1, THYEX3) | |
Results | Reference |
1* | J:111589 Fisher DA, Kivimae S, Hoshino J, Suriben R, Martin PM, Baxter N, Cheyette BN, Three Dact gene family members are expressed during embryonic development and in the adult brains of mice. Dev Dyn. 2006 Jul 31;235(9):2620-2630 |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
1* | J:158779 Kettunen P, Kivimae S, Keshari P, Klein OD, Cheyette BN, Luukko K, Dact1-3 mRNAs exhibit distinct expression domains during tooth development. Gene Expr Patterns. 2010 Feb-Mar;10(2-3):140-3 |
Dact2 dishevelled-binding antagonist of beta-catenin 2 (Synonyms: 2900084M21Rik, dapper2, Dpr2, Frd2) | |
Results | Reference |
1* | J:111589 Fisher DA, Kivimae S, Hoshino J, Suriben R, Martin PM, Baxter N, Cheyette BN, Three Dact gene family members are expressed during embryonic development and in the adult brains of mice. Dev Dyn. 2006 Jul 31;235(9):2620-2630 |
1* | J:158779 Kettunen P, Kivimae S, Keshari P, Klein OD, Cheyette BN, Luukko K, Dact1-3 mRNAs exhibit distinct expression domains during tooth development. Gene Expr Patterns. 2010 Feb-Mar;10(2-3):140-3 |
1* | J:210788 Li X, Florez S, Wang J, Cao H, Amendt BA, Dact2 represses PITX2 transcriptional activation and cell proliferation through Wnt/beta-catenin signaling during odontogenesis. PLoS One. 2013;8(1):e54868 |
Dact3 dishevelled-binding antagonist of beta-catenin 3 (Synonyms: EG666671) | |
Results | Reference |
1* | J:111589 Fisher DA, Kivimae S, Hoshino J, Suriben R, Martin PM, Baxter N, Cheyette BN, Three Dact gene family members are expressed during embryonic development and in the adult brains of mice. Dev Dyn. 2006 Jul 31;235(9):2620-2630 |
1* | J:158779 Kettunen P, Kivimae S, Keshari P, Klein OD, Cheyette BN, Luukko K, Dact1-3 mRNAs exhibit distinct expression domains during tooth development. Gene Expr Patterns. 2010 Feb-Mar;10(2-3):140-3 |
Dag1 dystroglycan 1 (Synonyms: alpha-dystroglycan, beta-dystroglycan, D9Wsu13e, DG, dystrophin associated glycoprotein 1) | |
Results | Reference |
1 | J:248927 Clements R, Turk R, Campbell KP, Wright KM, Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development. J Neurosci. 2017 Aug 30;37(35):8559-8574 |
1 | J:220324 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C, Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 1;142(5):871-82 |
1* | J:361965 Fujimoto T, Mori M, Tonosaki M, Yaoi T, Nakano K, Okamura T, Itoh K, Characterization of Dystrophin Dp71 Expression and Interaction Partners in Embryonic Brain Development: Implications for Duchenne/Becker Muscular Dystrophy. Mol Neurobiol. 2025 Jan 6; |
1 | J:250521 Hecht JH, Siegenthaler JA, Patterson KP, Pleasure SJ, Primary cellular meningeal defects cause neocortical dysplasia and dyslamination. Ann Neurol. 2010 Oct;68(4):454-64 |
Dagla diacylglycerol lipase, alpha (Synonyms: Nsddr) | |
Results | Reference |
3 | J:165476 Keimpema E, Barabas K, Morozov YM, Tortoriello G, Torii M, Cameron G, Yanagawa Y, Watanabe M, Mackie K, Harkany T, Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding. J Neurosci. 2010 Oct 20;30(42):13992-4007 |
1 | J:227268 Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Bjorklund P, Mackie K, Di Marzo V, Hokfelt TG, Dobrzyn A, Harkany T, Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6185-94 |
1 | J:171771 Wu CS, Zhu J, Wager-Miller J, Wang S, O'Leary D, Monory K, Lutz B, Mackie K, Lu HC, Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. Eur J Neurosci. 2010 Sep;32(5):693-706 |
Daglb diacylglycerol lipase, beta (Synonyms: E330036I19Rik) | |
Results | Reference |
2 | J:165476 Keimpema E, Barabas K, Morozov YM, Tortoriello G, Torii M, Cameron G, Yanagawa Y, Watanabe M, Mackie K, Harkany T, Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding. J Neurosci. 2010 Oct 20;30(42):13992-4007 |
1 | J:137203 Mulder J, Aguado T, Keimpema E, Barabas K, Ballester Rosado CJ, Nguyen L, Monory K, Marsicano G, Di Marzo V, Hurd YL, Guillemot F, Mackie K, Lutz B, Guzman M, Lu HC, Galve-Roperh I, Harkany T, Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning. Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8760-5 |
Dancr differentiation antagonizing non-protein coding RNA (Synonyms: 2700023E23Rik) | |
Results | Reference |
1* | J:212084 Herriges MJ, Swarr DT, Morley MP, Rathi KS, Peng T, Stewart KM, Morrisey EE, Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development. Genes Dev. 2014 Jun 15;28(12):1363-79 |
Dao D-amino acid oxidase (Synonyms: DAO, Dao-1, Dao1) | |
Results | Reference |
1 | J:307596 De Rosa A, Mastrostefano F, Di Maio A, Nuzzo T, Saitoh Y, Katane M, Isidori AM, Caputo V, Marotta P, Falco G, De Stefano ME, Homma H, Usiello A, Errico F, Prenatal expression of D-aspartate oxidase causes early cerebral D-aspartate depletion and influences brain morphology and cognitive functions at adulthood. Amino Acids. 2020 Apr;52(4):597-617 |
Daxx Fas death domain-associated protein | |
Results | Reference |
1* | J:347585 Leon NY, Le TNU, Garvie A, Wong LH, Bagheri-Fam S, Harley VR, Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. iScience. 2024 May 17;27(5):109629 |
Dazl deleted in azoospermia-like (Synonyms: Dazla, Daz-like, Tpx-2, Tpx2) | |
Results | Reference |
1 | J:343469 Ding Y, He Z, Sha Y, Kee K, Li L, Eif4enif1 haploinsufficiency disrupts oocyte mitochondrial dynamics and leads to subfertility. Development. 2023 Dec 1;150(23):dev202151 |
1 | J:307864 Horisawa-Takada Y, Kodera C, Takemoto K, Sakashita A, Horisawa K, Maeda R, Shimada R, Usuki S, Fujimura S, Tani N, Matsuura K, Akiyama T, Suzuki A, Niwa H, Tachibana M, Ohba T, Katabuchi H, Namekawa SH, Araki K, Ishiguro KI, Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis. Nat Commun. 2021 Jun 1;12(1):3184 |
1 | J:326085 Huang TC, Wang YF, Vazquez-Ferrer E, Theofel I, Requena CE, Hanna CW, Kelsey G, Hajkova P, Sex-specific chromatin remodelling safeguards transcription in germ cells. Nature. 2021 Dec;600(7890):737-742 |
1* | J:64334 Nadler JJ, Braun RE, Fanconi anemia complementation group C is required for proliferation of murine primordial germ cells [letter]. Genesis. 2000 Jul;27(3):117-23 |
1* | J:87821 Olesen C, Moller M, Byskov AG, Tesmin transcription is regulated differently during male and female meiosis. Mol Reprod Dev. 2004 Jan;67(1):116-26 |
1* | J:42612 Ruggiu M, Speed R, Taggart M, McKay SJ, Kilanowski F, Saunders P , Dorin J , Cooke HJ, The mouse Dazla gene encodes a cytoplasmic protein essential for gametogenesis. Nature. 1997 Sep 4;389(6646):73-7 |
1* | J:47337 Seligman J, Page DC, The Dazh gene is expressed in male and female embryonic gonads before germ cell sex differentiation. Biochem Biophys Res Commun. 1998 Apr 28;245(3):878-82 |
1* | J:242348 Soh YQS, Mikedis MM, Kojima M, Godfrey AK, de Rooij DG, Page DC, Meioc maintains an extended meiotic prophase I in mice. PLoS Genet. 2017 Apr;13(4):e1006704 |
1 | J:306228 Song HW, Dann CT, McCarrey JR, Meistrich ML, Cornwall GA, Wilkinson MF, Dynamic expression pattern and subcellular localization of the Rhox10 homeobox transcription factor during early germ cell development. Reproduction. 2012 May;143(5):611-24 |
1 | J:362758 Zhang L, Li Y, Hu Y, Chen M, Cen C, Chen M, Lin L, Zhou J, Wang M, Cui X, Tang F, Gao F, Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression. FASEB J. 2022 Feb;36(2):e22131 |
Dbh dopamine beta hydroxylase | |
Results | Reference |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1 | J:166770 Coppola E, d'Autreaux F, Rijli FM, Brunet JF, Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation. Development. 2010 Dec;137(24):4211-20 |
1 | J:223161 Gahring LC, Myers E, Palumbos S, Rogers SW, Nicotinic receptor Alpha7 expression during mouse adrenal gland development. PLoS One. 2014;9(8):e103861 |
1* | J:46409 Hirsch MR, Tiveron MC, Guillemot F, Brunet JF, Goridis C, Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system. Development. 1998 Feb;125(4):599-608 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
1 | J:152424 Jacob J, Storm R, Castro DS, Milton C, Pla P, Guillemot F, Birchmeier C, Briscoe J, Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain. Development. 2009 Jul;136(14):2477-85 |
1 | J:123685 Saarimaki-Vire J, Peltopuro P, Lahti L, Naserke T, Blak AA, Vogt Weisenhorn DM, Yu K, Ornitz DM, Wurst W, Partanen J, Fibroblast growth factor receptors cooperate to regulate neural progenitor properties in the developing midbrain and hindbrain. J Neurosci. 2007 Aug 8;27(32):8581-92 |
1 | J:173638 Schmidt M, Huber L, Majdazari A, Schutz G, Williams T, Rohrer H, The transcription factors AP-2beta and AP-2alpha are required for survival of sympathetic progenitors and differentiated sympathetic neurons. Dev Biol. 2011 Jul 1;355(1):89-100 |
1 | J:142435 Shi M, Guo C, Dai JX, Ding YQ, DCC is required for the tangential migration of noradrenergic neurons in locus coeruleus of mouse brain. Mol Cell Neurosci. 2008 Dec;39(4):529-38 |
1 | J:198880 Shi M, Hu ZL, Zheng MH, Song NN, Huang Y, Zhao G, Han H, Ding YQ, Notch-Rbpj signaling is required for the development of noradrenergic neurons in the mouse locus coeruleus. J Cell Sci. 2012 Sep 15;125(Pt 18):4320-32 |
1 | J:320700 Shtukmaster S, Narasimhan P, El Faitwri T, Stubbusch J, Ernsberger U, Rohrer H, Unsicker K, Huber K, MiR-124 is differentially expressed in derivatives of the sympathoadrenal cell lineage and promotes neurite elongation in chromaffin cells. Cell Tissue Res. 2016 Aug;365(2):225-32 |
1* | J:286599 Song NN, Ma P, Zhang Q, Zhang L, Wang H, Zhang L, Zhu L, He CH, Mao B, Ding YQ, Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199 |
2 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
1 | J:201069 Stubbusch J, Narasimhan P, Huber K, Unsicker K, Rohrer H, Ernsberger U, Synaptic protein and pan-neuronal gene expression and their regulation by Dicer-dependent mechanisms differ between neurons and neuroendocrine cells. Neural Dev. 2013 Aug 20;8(1):16 |
1 | J:208894 VanDusen NJ, Vincentz JW, Firulli BA, Howard MJ, Rubart M, Firulli AB, Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal death. Dev Biol. 2014 Apr 15;388(2):149-58 |
Dbi diazepam binding inhibitor (Synonyms: Acbp, diazepam-binding inhibitor, endozepine, EP) | |
Results | Reference |
1 | J:329939 Everlien I, Yen TY, Liu YC, Di Marco B, Vazquez-Marin J, Centanin L, Alfonso J, Monyer H, Diazepam binding inhibitor governs neurogenesis of excitatory and inhibitory neurons during embryonic development via GABA signaling. Neuron. 2022 Oct 5;110(19):3139-3153.e6 |
Dbn1 drebrin 1 (Synonyms: drebrin A, drebrin E2) | |
Results | Reference |
1 | J:312372 Karnam S, Maddala R, Stiber JA, Rao PV, Drebrin, an actin-binding protein, is required for lens morphogenesis and growth. Dev Dyn. 2021 Nov;250(11):1600-1617 |
1* | J:214682 Wei Z, Sun M, Liu X, Zhang J, Jin Y, Rufy3, a protein specifically expressed in neurons, interacts with actin-bundling protein Fascin to control the growth of axons. J Neurochem. 2014 Sep;130(5):678-92 |
Dbnl drebrin-like (Synonyms: ABP1, mAbp1, SH3P7) | |
Results | Reference |
1* | J:273015 Inoue S, Hayashi K, Fujita K, Tagawa K, Okazawa H, Kubo KI, Nakajima K, Drebrin-like (Dbnl) Controls Neuronal Migration via Regulating N-Cadherin Expression in the Developing Cerebral Cortex. J Neurosci. 2019 Jan 23;39(4):678-691 |
Dbp D site albumin promoter binding protein | |
Results | Reference |
1* | J:161413 Ratajczak CK, Herzog ED, Muglia LJ, Clock gene expression in gravid uterus and extra-embryonic tissues during late gestation in the mouse. Reprod Fertil Dev. 2010;22(5):743-50 |
Dbt dihydrolipoamide branched chain transacylase E2 (Synonyms: BCKAD E2, D3Wsu60e, dihydrolipoyllysine-residue (2-methylpropanoyl)transferase, dihydrolipoyl transacylase) | |
Results | Reference |
1* | J:48080 Doering CB, Coursey C, Spangler W, Danner DJ, Murine branched chain alpha-ketoacid dehydrogenase kinase; cDNA cloning, tissue distribution, and temporal expression during embryonic development. Gene. 1998 Jun 8;212(2):213-9 |
Dbx1 developing brain homeobox 1 (Synonyms: Dbx, Mmox C) | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1 | J:327338 Sartoretti MM, Campetella CA, Lanuza GM, Dbx1 controls the development of astrocytes of the intermediate spinal cord by modulating Notch signaling. Development. 2022 Aug 1;149(15):dev200750 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:132518 Vue TY, Aaker J, Taniguchi A, Kazemzadeh C, Skidmore JM, Martin DM, Martin JF, Treier M, Nakagawa Y, Characterization of progenitor domains in the developing mouse thalamus. J Comp Neurol. 2007 Nov 1;505(1):73-91 |
Dbx2 developing brain homeobox 2 (Synonyms: 9430056A22Rik, LOC383001) | |
Results | Reference |
1 | J:314124 Gao Y, Duque-Wilckens N, Aljazi MB, Wu Y, Moeser AJ, Mias GI, Robison AJ, He J, Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors. Commun Biol. 2021 Jun 18;4(1):756 |
Dcaf5 DDB1 and CUL4 associated factor 5 (Synonyms: 9430020B07Rik, BCRG2, BCRP2, mKIAA1824, Wdr22) | |
Results | Reference |
1 | J:346895 Guo P, Lim RC, Rajawasam K, Trinh T, Sun H, Zhang H, A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis. Elife. 2024 Feb 12;13 |
Dcc DCC netrin 1 receptor (Synonyms: C030036D22Rik, deleted in colorectal carcinoma, Igdcc1) | |
Results | Reference |
1* | J:65295 Barallobre MJ, Del Rio JA, Alcantara S, Borrell V, Aguado F, Ruiz M, Carmona MA, Martin M, Fabre M, Yuste R, Tessier-Lavigne M, Soriano E, Aberrant development of hippocampal circuits and altered neural activity in netrin 1-deficient mice. Development. 2000 Nov;127(22):4797-810 |
1* | J:60855 Birgbauer E, Cowan CA, Sretavan DW, Henkemeyer M, Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina. Development. 2000 Mar;127(6):1231-41 |
1* | J:121833 Bonnin A, Torii M, Wang L, Rakic P, Levitt P, Serotonin modulates the response of embryonic thalamocortical axons to netrin-1. Nat Neurosci. 2007 May;10(5):588-97 |
1 | J:297714 Brignani S, Raj DDA, Schmidt ERE, Dudukcu O, Adolfs Y, De Ruiter AA, Rybiczka-Tesulov M, Verhagen MG, van der Meer C, Broekhoven MH, Moreno-Bravo JA, Grossouw LM, Dumontier E, Cloutier JF, Chedotal A, Pasterkamp RJ, Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development. Neuron. 2020 Aug 19;107(4):684-702.e9 |
1* | J:308673 Company V, Andreu-Cervera A, Madrigal MP, Andres B, Almagro-Garcia F, Chedotal A, Lopez-Bendito G, Martinez S, Echevarria D, Moreno-Bravo JA, Puelles E, Netrin 1-Mediated Role of the Substantia Nigra Pars Compacta and Ventral Tegmental Area in the Guidance of the Medial Habenular Axons. Front Cell Dev Biol. 2021;9:682067 |
3* | J:30261 Cooper HM, Armes P, Britto J, Gad J, Wilks AF, Cloning of the mouse homologue of the deleted in colorectal cancer gene (mDCC) and its expression in the developing mouse embryo. Oncogene. 1995 Dec 7;11(11):2243-54 |
2* | J:84360 Dalvin S, Anselmo MA, Prodhan P, Komatsuzaki K, Schnitzer JJ, Kinane TB, Expression of Netrin-1 and its two receptors DCC and UNC5H2 in the developing mouse lung. Gene Expr Patterns. 2003 Jun;3(3):279-83 |
1 | J:58438 Deiner MS, Sretavan DW, Altered midline axon pathways and ectopic neurons in the developing hypothalamus of netrin-1- and DCC-deficient mice. J Neurosci. 1999 Nov 15;19(22):9900-12 |
1 | J:152844 Driskell RR, Giangreco A, Jensen KB, Mulder KW, Watt FM, Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis. Development. 2009 Aug;136(16):2815-23 |
1 | J:54722 Engelkamp D, Rashbass P, Seawright A, van Heyningen V, Role of Pax6 in development of the cerebellar system. Development. 1999 Aug;126(16):3585-96 |
2* | J:62806 Gad JM, Keeling SL, Shu T, Richards LJ, Cooper HM, The spatial and temporal expression patterns of netrin receptors, DCC and neogenin, in the developing mouse retina. Exp Eye Res. 2000 Jun;70(6):711-22 |
1* | J:45336 Gad JM, Keeling SL, Wilks AF, Tan SS, Cooper HM, The expression patterns of guidance receptors, DCC and Neogenin, are spatially and temporally distinct throughout mouse embryogenesis. Dev Biol. 1997 Dec 15;192(2):258-73 |
1 | J:278733 Hossain MM, Tsuzuki T, Sakakibara K, Imaizumi F, Ikegaya A, Inagaki M, Takahashi I, Ito T, Takamatsu H, Kumanogoh A, Negishi T, Yukawa K, PlexinA1 is crucial for the midline crossing of callosal axons during corpus callosum development in BALB/cAJ mice. PLoS One. 2019;14(8):e0221440 |
1 | J:94593 Inaki K, Nishimura S, Nakashiba T, Itohara S, Yoshihara Y, Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules. J Comp Neurol. 2004 Nov 15;479(3):243-56 |
1 | J:348685 Masuda A, Nishida K, Ajima R, Saga Y, Bakhtan M, Klar A, Hirata T, Zhu Y, A global gene regulatory program and its region-specific regulator partition neurons into commissural and ipsilateral projection types. Sci Adv. 2024 May 24;10(21):eadk2149 |
1* | J:278827 Murcia-Belmonte V, Coca Y, Vegar C, Negueruela S, de Juan Romero C, Valino AJ, Sala S, DaSilva R, Kania A, Borrell V, Martinez LM, Erskine L, Herrera E, A Retino-retinal Projection Guided by Unc5c Emerged in Species with Retinal Waves. Curr Biol. 2019 Apr 1;29(7):1149-1160.e4 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
2 | J:140549 Ratcliffe EM, Setru SU, Chen JJ, Li ZS, D'Autreaux F, Gershon MD, Netrin/DCC-mediated attraction of vagal sensory axons to the fetal mouse gut. J Comp Neurol. 2006 Oct 10;498(5):567-80 |
1 | J:125013 Schmid T, Kruger M, Braun T, NSCL-1 and -2 control the formation of precerebellar nuclei by orchestrating the migration of neuronal precursor cells. J Neurochem. 2007 Sep;102(6):2061-72 |
1 | J:215618 Schmidt ER, Brignani S, Adolfs Y, Lemstra S, Demmers J, Vidaki M, Donahoo AL, Lillevali K, Vasar E, Richards LJ, Karagogeos D, Kolk SM, Pasterkamp RJ, Subdomain-mediated axon-axon signaling and chemoattraction cooperate to regulate afferent innervation of the lateral habenula. Neuron. 2014 Jul 16;83(2):372-87 |
1 | J:166950 Shi M, Zheng MH, Liu ZR, Hu ZL, Huang Y, Chen JY, Zhao G, Han H, Ding YQ, DCC is specifically required for the survival of retinal ganglion and displaced amacrine cells in the developing mouse retina. Dev Biol. 2010 Dec 1;348(1):87-96 |
1 | J:110263 Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM, Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat Neurosci. 2006 Jun;9(6):787-97 |
1* | J:104160 Tole S, Gutin G, Bhatnagar L, Remedios R, Hebert JM, Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev Biol. 2006 Jan 1;289(1):141-51 |
1 | J:103328 Waage-Baudet H, Dunty WC Jr, Dehart DB, Hiller S, Sulik KK, Immunohistochemical and microarray analyses of a mouse model for the smith-lemli-opitz syndrome. Dev Neurosci. 2005;27(6):378-96 |
1 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
1 | J:294199 Zhu Y, Hirata T, Mackay F, Murakami F, Chemokine receptor CXCR7 non-cell-autonomously controls pontine neuronal migration and nucleus formation. Sci Rep. 2020 Jul 16;10(1):11830 |
Dchs1 dachsous cadherin related 1 (Synonyms: 3110041P15Rik, C130033F22Rik) | |
Results | Reference |
1 | J:293199 Crespo-Enriquez I, Hodgson T, Zakaria S, Cadoni E, Shah M, Allen S, Al-Khishali A, Mao Y, Yiu A, Petzold J, Villagomez-Olea G, Pitsillides AA, Irvine KD, Francis-West P, Dchs1-Fat4 regulation of osteogenic differentiation in mouse. Development. 2019 Jul 29;146(14):dev176776 |
Dclk1 doublecortin-like kinase 1 (Synonyms: 1700113D08Rik, 2810480F11Rik, Click-I, CPG16, Dcamkl1, Dcl, DCLK, mKIAA0369) | |
Results | Reference |
1 | J:186296 Saqui-Salces M, Keeley TM, Grosse AS, Qiao XT, El-Zaatari M, Gumucio DL, Samuelson LC, Merchant JL, Gastric tuft cells express DCLK1 and are expanded in hyperplasia. Histochem Cell Biol. 2011 Aug;136(2):191-204 |
1* | J:133440 Tuy FP, Saillour Y, Kappeler C, Chelly J, Francis F, Alternative transcripts of Dclk1 and Dclk2 and their expression in doublecortin knockout mice. Dev Neurosci. 2008;30(1-3):171-86 |
1 | J:202498 Zou W, Greenblatt MB, Brady N, Lotinun S, Zhai B, de Rivera H, Singh A, Sun J, Gygi SP, Baron R, Glimcher LH, Jones DC, The microtubule-associated protein DCAMKL1 regulates osteoblast function via repression of Runx2. J Exp Med. 2013 Aug 26;210(9):1793-806 |
Dclk2 doublecortin-like kinase 2 (Synonyms: 6330415M09Rik, Click-II, Dcamkl2) | |
Results | Reference |
1* | J:133440 Tuy FP, Saillour Y, Kappeler C, Chelly J, Francis F, Alternative transcripts of Dclk1 and Dclk2 and their expression in doublecortin knockout mice. Dev Neurosci. 2008;30(1-3):171-86 |
Dcn decorin (Synonyms: DC, SLRR1B) | |
Results | Reference |
2 | J:185118 Galli GG, Honnens de Lichtenberg K, Carrara M, Hans W, Wuelling M, Mentz B, Multhaupt HA, Fog CK, Jensen KT, Rappsilber J, Vortkamp A, Coulton L, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Calogero RA, Couchman JR, Lund AH, Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone. PLoS Genet. 2012 May;8(5):e1002711 |
1 | J:83512 Hikake T, Mori T, Iseki K, Hagino S, Zhang Y, Takagi H, Yokoya S, Wanaka A, Comparison of expression patterns between CREB family transcription factor OASIS and proteoglycan core protein genes during murine tooth development. Anat Embryol (Berl). 2003 Apr;206(5):373-80 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:175747 Liu W, Watson SS, Lan Y, Keene DR, Ovitt CE, Liu H, Schweitzer R, Jiang R, The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis. Mol Cell Biol. 2010 Oct;30(20):4797-807 |
1* | J:320343 Randilini A, Fujikawa K, Shibata S, An in situ hybridization study of decorin and biglycan mRNA in mouse osteoblasts in vivo. Anat Sci Int. 2021 Mar;96(2):265-272 |
1* | J:284147 Velecela V, Torres-Cano A, Garcia-Melero A, Ramiro-Pareta M, Muller-Sanchez C, Segarra-Mondejar M, Chau YY, Campos-Bonilla B, Reina M, Soriano FX, Hastie ND, Martinez FO, Martinez-Estrada OM, Epicardial cell shape and maturation are regulated by Wt1 via transcriptional control of Bmp4. Development. 2019 Oct 17;146(20):dev178723 |
Dcp1a decapping mRNA 1A (Synonyms: 1110066A22Rik, 4930568L04Rik, D14Ertd817e, Mitc1, SMIF) | |
Results | Reference |
1 | J:184034 De Fazio S, Bartonicek N, Di Giacomo M, Abreu-Goodger C, Sankar A, Funaya C, Antony C, Moreira PN, Enright AJ, O'Carroll D, The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements. Nature. 2011 Dec 8;480(7376):259-63 |
1 | J:230058 Suzuki A, Niimi Y, Shinmyozu K, Zhou Z, Kiso M, Saga Y, Dead end1 is an essential partner of NANOS2 for selective binding of target RNAs in male germ cell development. EMBO Rep. 2016 Jan;17(1):37-46 |
Dcp2 decapping mRNA 2 (Synonyms: 2410015D23Rik, 5730537H01Rik) | |
Results | Reference |
1* | J:346062 Perez RC, Yang X, Familari M, Martinez G, Lovicu FJ, Hime GR, de Iongh RU, TOB1 and TOB2 mark distinct RNA processing granules in differentiating lens fiber cells. J Mol Histol. 2024 Feb;55(1):121-138 |
1* | J:166846 Song MG, Li Y, Kiledjian M, Multiple mRNA decapping enzymes in mammalian cells. Mol Cell. 2010 Nov 12;40(3):423-32 |
1 | J:157579 Suzuki A, Igarashi K, Aisaki K, Kanno J, Saga Y, NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3594-9 |
Dct dopachrome tautomerase (Synonyms: TRP-2, TRP2, tyrosinase-related protein-2, Tyrp-2, Tyrp2) | |
Results | Reference |
1 | J:197180 Buniello A, Hardisty-Hughes RE, Pass JC, Bober E, Smith RJ, Steel KP, Headbobber: a combined morphogenetic and cochleosaccular mouse model to study 10qter deletions in human deafness. PLoS One. 2013;8(2):e56274 |
1 | J:288683 Gacem N, Kavo A, Zerad L, Richard L, Mathis S, Kapur RP, Parisot M, Amiel J, Dufour S, de la Grange P, Pingault V, Vallat JM, Bondurand N, ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. Nat Commun. 2020 Jan 10;11(1):198 |
2 | J:185553 Hari L, Miescher I, Shakhova O, Suter U, Chin L, Taketo M, Richardson WD, Kessaris N, Sommer L, Temporal control of neural crest lineage generation by Wnt/beta-catenin signaling. Development. 2012 Jun;139(12):2107-17 |
1* | J:13562 Hodgkinson CA, Moore KJ, Nakayama A, Steingrimsson E, Copeland NG, Jenkins NA, Arnheiter H, Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein. Cell. 1993 Jul 30;74(2):395-404 |
1 | J:139051 Inoue-Narita T, Hamada K, Sasaki T, Hatakeyama S, Fujita S, Kawahara K, Sasaki M, Kishimoto H, Eguchi S, Kojima I, Beermann F, Kimura T, Osawa M, Itami S, Mak TW, Nakano T, Manabe M, Suzuki A, Pten deficiency in melanocytes results in resistance to hair graying and susceptibility to carcinogen-induced melanomagenesis. Cancer Res. 2008 Jul 15;68(14):5760-8 |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
1* | J:46130 Nakayama A, Nguyen MT, Chen CC, Opdecamp K, Hodgkinson CA, Arnheiter H, Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently. Mech Dev. 1998 Jan;70(1-2):155-66 |
1 | J:357839 Nasim S, Abujamra BA, Chaparro D, Nogueira PDS, Riva A, Hutcheson JD, Kos L, Multiple cell types including melanocytes contribute to elastogenesis in the developing murine aortic valve. Sci Rep. 2024 Oct 26;14(1):25481 |
1 | J:19441 Pavan WJ, Tilghman SM, Piebald lethal (sl) acts early to disrupt the development of neural crest-derived melanocytes. Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7159-63 |
1* | J:70836 Romand R, Albuisson E, Niederreither K, Fraulob V, Chambon P, Dolle P, Specific expression of the retinoic acid-synthesizing enzyme RALDH2 during mouse inner ear development. Mech Dev. 2001 Aug;106(1-2):185-9 |
1* | J:31646 Steel KP, Davidson DR, Jackson IJ, TRP-2/DT, a new early melanoblast marker, shows that steel growth factor (c-kit ligand) is a survival factor. Development. 1992 Aug;115(4):1111-9 |
1 | J:282279 Ustun Y, Reibetanz M, Brachvogel B, Nischt R, Eckes B, Zigrino P, Krieg T, Dual role of laminin511 in regulating melanocyte migration and differentiation. Matrix Biol. 2019 Jul;80:59-71 |
Dctn1 dynactin 1
(Synonyms:
Glued, p150, p150 | |
Results | Reference |
1 | J:294113 Lough KJ, Byrd KM, Descovich CP, Spitzer DC, Bergman AJ, Beaudoin GM 3rd, Reichardt LF, Williams SE, Telophase correction refines division orientation in stratified epithelia. Elife. 2019 Dec 13;8:e49249 |
Dcx doublecortin (Synonyms: Dbct, lissencephaly, X-linked (doublecortin)) | |
Results | Reference |
1 | J:181188 Aoki H, Hara A, Era T, Kunisada T, Yamada Y, Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development. 2012 Feb;139(4):667-77 |
1* | J:333828 Blommers M, Stanton-Turcotte D, Iulianella A, Retinal neuroblast migration and ganglion cell layer organization require the cytoskeletal-interacting protein Mllt11. Dev Dyn. 2023 Feb;252(2):305-319 |
1 | J:88495 Chae TH, Kim S, Marz KE, Hanson PI, Walsh CA, The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate. Nat Genet. 2004 Mar;36(3):264-70 |
1* | J:242692 Coulthard LG, Hawksworth OA, Li R, Balachandran A, Lee JD, Sepehrband F, Kurniawan N, Jeanes A, Simmons DG, Wolvetang E, Woodruff TM, Complement C5aR1 Signaling Promotes Polarization and Proliferation of Embryonic Neural Progenitor Cells through PKCzeta. J Neurosci. 2017 May 31;37(22):5395-5407 |
1 | J:94756 Feng Y, Walsh CA, Mitotic spindle regulation by Nde1 controls cerebral cortical size. Neuron. 2004 Oct 14;44(2):279-93 |
2* | J:56086 Francis F, Koulakoff A, Boucher D, Chafey P, Schaar B, Vinet MC, Friocourt G, McDonnell N, Reiner O, Kahn A, McConnell SK, Berwald-Netter Y, Denoulet P, Chelly J, Doublecortin is a developmentally regulated, microtubule-associated protein expressed in migrating and differentiating neurons. Neuron. 1999 Jun;23(2):247-56 |
1 | J:166928 Hoeck JD, Jandke A, Blake SM, Nye E, Spencer-Dene B, Brandner S, Behrens A, Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun. Nat Neurosci. 2010 Nov;13(11):1365-72 |
1 | J:108229 Kappeler C, Saillour Y, Baudoin JP, Tuy FP, Alvarez C, Houbron C, Gaspar P, Hamard G, Chelly J, Metin C, Francis F, Branching and nucleokinesis defects in migrating interneurons derived from doublecortin knockout mice. Hum Mol Genet. 2006 May 1;15(9):1387-400 |
1 | J:234375 Kim H, Jang WY, Kang MC, Jeong J, Choi M, Sung Y, Park S, Kwon W, Jang S, Kim MO, Kim SH, Ryoo ZY, TET1 contributes to neurogenesis onset time during fetal brain development in mice. Biochem Biophys Res Commun. 2016 Mar 18;471(4):437-43 |
1* | J:347773 Kim HY, Kang B, Lee PR, Kim K, Hong GS, Expression patterns of Piezo1 in the developing mouse forebrain. Brain Struct Funct. 2024 Apr;229(3):759-773 |
1 | J:254235 Lanctot AA, Guo Y, Le Y, Edens BM, Nowakowski RS, Feng Y, Loss of Brap Results in Premature G1/S Phase Transition and Impeded Neural Progenitor Differentiation. Cell Rep. 2017 Aug 1;20(5):1148-1160 |
1 | J:227268 Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Bjorklund P, Mackie K, Di Marzo V, Hokfelt TG, Dobrzyn A, Harkany T, Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6185-94 |
1 | J:192488 McLoughlin HS, Fineberg SK, Ghosh LL, Tecedor L, Davidson BL, Dicer is required for proliferation, viability, migration and differentiation in corticoneurogenesis. Neuroscience. 2012 Oct 25;223:285-95 |
1 | J:272073 Nicola Z, Fabel K, Kempermann G, Development of the adult neurogenic niche in the hippocampus of mice. Front Neuroanat. 2015;9:53 |
1 | J:135129 Ohshima T, Hirasawa M, Tabata H, Mutoh T, Adachi T, Suzuki H, Saruta K, Iwasato T, Itohara S, Hashimoto M, Nakajima K, Ogawa M, Kulkarni AB, Mikoshiba K, Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex. Development. 2007 Jun;134(12):2273-82 |
1 | J:187391 Pacal M, Bremner R, Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Dev Dyn. 2012 Oct;241(10):1525-44 |
1 | J:300967 Pajovic S, Siddaway R, Bridge T, Sheth J, Rakopoulos P, Kim B, Ryall S, Agnihotri S, Phillips L, Yu M, Li C, Milos S, Patel P, Srikanthan D, Huang A, Hawkins C, Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer. Nat Commun. 2020 Dec 4;11(1):6216 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:204287 Stegeman S, Jolly LA, Premarathne S, Gecz J, Richards LJ, Mackay-Sim A, Wood SA, Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFbeta-mediated axonogenesis. PLoS One. 2013;8(7):e68287 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1 | J:77999 Sugitani Y, Nakai S, Minowa O, Nishi M, Jishage K, Kawano H, Mori K, Ogawa M, Noda T, Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. Genes Dev. 2002 Jul 15;16(14):1760-5 |
1 | J:360973 Tang I, Nisal A, Reed A, Ware TB, Johansen A, Zaki MS, Cravatt BF, Gleeson JG, Lipidomic profiling of mouse brain and human neuron cultures reveals a role for Mboat7 in mTOR-dependent neuronal migration. Sci Transl Med. 2025 Jan;17(779):eadp5247 |
1 | J:309451 Vinsland E, Baskaran P, Mihaylov SR, Hobbs C, Wood H, Bouybayoune I, Shah K, Houart C, Tee AR, Murn J, Fernandes C, Bateman JM, The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021 Aug 11;11(1):16299 |
1* | J:353555 Wang W, Yin C, Wen S, Liu Z, Wang B, Zeng B, Sun L, Zhou X, Zhong S, Zhang J, Ma W, Wu Q, Wang X, DCX knockout ferret reveals a neurogenic mechanism in cortical development. Cell Rep. 2024 Aug 27;43(8):114508 |
1 | J:285763 Xu M, Han X, Liu R, Li Y, Qi C, Yang Z, Zhao C, Gao J, PDK1 Deficit Impairs the Development of the Dentate Gyrus in Mice. Cereb Cortex. 2019 Mar 1;29(3):1185-1198 |
1 | J:264125 Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z, SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. Development. 2018 Jul 23;145(14):dev165456 |
1 | J:363160 Yuizumi N, Harada Y, Kuniya T, Sunabori T, Koike M, Wakabayashi M, Ishihama Y, Suzuki Y, Kawaguchi D, Gotoh Y, Maintenance of neural stem-progenitor cells by the lysosomal biosynthesis regulators TFEB and TFE3 in the embryonic mouse telencephalon. Stem Cells. 2021 Jul;39(7):929-944 |
Ddb1 damage specific DNA binding protein 1 (Synonyms: damage-specific DNA-binding protein, DNA repair, DNA repair protein, p127-Ddb1) | |
Results | Reference |
1 | J:125911 Cang Y, Zhang J, Nicholas SA, Kim AL, Zhou P, Goff SP, DDB1 is essential for genomic stability in developing epidermis. Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2733-7 |
Ddc dopa decarboxylase (Synonyms: Aadc, aromatic L-amino acid decarboxylase) | |
Results | Reference |
1 | J:324028 Bonthuis PJ, Steinwand S, Stacher Horndli CN, Emery J, Huang WC, Kravitz S, Ferris E, Gregg C, Noncanonical genomic imprinting in the monoamine system determines naturalistic foraging and brain-adrenal axis functions. Cell Rep. 2022 Mar 8;38(10):110500 |
1 | J:152424 Jacob J, Storm R, Castro DS, Milton C, Pla P, Guillemot F, Birchmeier C, Briscoe J, Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain. Development. 2009 Jul;136(14):2477-85 |
1 | J:329940 Juan AM, Foong YH, Thorvaldsen JL, Lan Y, Leu NA, Rurik JG, Li L, Krapp C, Rosier CL, Epstein JA, Bartolomei MS, Tissue-specific Grb10/Ddc insulator drives allelic architecture for cardiac development. Mol Cell. 2022 Oct 6;82(19):3613-3631.e7 |
1* | J:308675 Prickett AR, Montibus B, Barkas N, Amante SM, Franco MM, Cowley M, Puszyk W, Shannon MF, Irving MD, Madon-Simon M, Ward A, Schulz R, Baldwin HS, Oakey RJ, Imprinted Gene Expression and Function of the Dopa Decarboxylase Gene in the Developing Heart. Front Cell Dev Biol. 2021;9:676543 |
1* | J:286599 Song NN, Ma P, Zhang Q, Zhang L, Wang H, Zhang L, Zhu L, He CH, Mao B, Ding YQ, Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199 |
Ddi1 DNA-damage inducible 1 (Synonyms: 1700011N24Rik) | |
Results | Reference |
2* | J:261900 Ramirez J, Lectez B, Osinalde N, Siva M, Elu N, Aloria K, Prochazkova M, Perez C, Martinez-Hernandez J, Barrio R, Saskova KG, Arizmendi JM, Mayor U, Quantitative proteomics reveals neuronal ubiquitination of Rngo/Ddi1 and several proteasomal subunits by Ube3a, accounting for the complexity of Angelman syndrome. Hum Mol Genet. 2018 Jun 1;27(11):1955-1971 |
Ddi2 DNA-damage inducible protein 2 (Synonyms: 1110056G13Rik, 1700027M01Rik, 9130022E05Rik) | |
Results | Reference |
1* | J:261900 Ramirez J, Lectez B, Osinalde N, Siva M, Elu N, Aloria K, Prochazkova M, Perez C, Martinez-Hernandez J, Barrio R, Saskova KG, Arizmendi JM, Mayor U, Quantitative proteomics reveals neuronal ubiquitination of Rngo/Ddi1 and several proteasomal subunits by Ube3a, accounting for the complexity of Angelman syndrome. Hum Mol Genet. 2018 Jun 1;27(11):1955-1971 |
Ddit3 DNA-damage inducible transcript 3 (Synonyms: C/EBP homoologous protein 10, chop, CHOP-10, CHOP10, gadd153) | |
Results | Reference |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
1 | J:211963 Kawakami T, Yoshimi M, Kadota Y, Inoue M, Sato M, Suzuki S, Prolonged endoplasmic reticulum stress alters placental morphology and causes low birth weight. Toxicol Appl Pharmacol. 2014 Mar 1;275(2):134-44 |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
1 | J:265679 Wang B, Joo JH, Mount R, Teubner BJW, Krenzer A, Ward AL, Ichhaporia VP, Adams EJ, Khoriaty R, Peters ST, Pruett-Miller SM, Zakharenko SS, Ginsburg D, Kundu M, The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018 Aug 1;128(8):3319-3332 |
1 | J:172737 Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RA, Peterson AS, Solloway MJ, Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol. 2011 May 30;193(5):935-51 |
1 | J:342871 Xiang J, Pompetti AJ, Faranda AP, Wang Y, Novo SG, Li DW, Duncan MK, ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment. Cells. 2023 Nov 16;12(22) |
Ddit4 DNA-damage-inducible transcript 4 (Synonyms: 5830413E08Rik, Dig2, REDD1, Rtp801) | |
Results | Reference |
1 | J:170677 Malagelada C, Lopez-Toledano MA, Willett RT, Jin ZH, Shelanski ML, Greene LA, RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration. J Neurosci. 2011 Mar 2;31(9):3186-96 |
1* | J:186462 Notini AJ, McClive PJ, Meachem SJ, van den Bergen JA, Western PS, Gustin SE, Harley VR, Koopman P, Sinclair AH, Redd1 is a novel marker of testis development but is not required for normal male reproduction. Sex Dev. 2012;6(5):223-30 |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
Ddo D-aspartate oxidase (Synonyms: 5330420D20Rik, 5730402C02Rik) | |
Results | Reference |
1 | J:307596 De Rosa A, Mastrostefano F, Di Maio A, Nuzzo T, Saitoh Y, Katane M, Isidori AM, Caputo V, Marotta P, Falco G, De Stefano ME, Homma H, Usiello A, Errico F, Prenatal expression of D-aspartate oxidase causes early cerebral D-aspartate depletion and influences brain morphology and cognitive functions at adulthood. Amino Acids. 2020 Apr;52(4):597-617 |
Ddr1 discoidin domain receptor family, member 1 (Synonyms: Cak, CD167a) | |
Results | Reference |
2* | J:32743 Perez JL, Jing SQ, Wong TW, Identification of two isoforms of the Cak receptor kinase that are coexpressed in breast tumor cell lines. Oncogene. 1996 Apr 4;12(7):1469-77 |
Ddr2 discoidin domain receptor family, member 2 (Synonyms: Ntrkr3) | |
Results | Reference |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
1 | J:146619 Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong TT, Shaw RM, Srivastava D, Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell. 2009 Feb;16(2):233-44 |
1 | J:327295 Mohamed FF, Ge C, Cowling RT, Lucas D, Hallett SA, Ono N, Binrayes AA, Greenberg B, Franceschi RT, The collagen receptor, discoidin domain receptor 2, functions in Gli1-positive skeletal progenitors and chondrocytes to control bone development. Bone Res. 2022 Feb 9;10(1):11 |
1 | J:334575 Mohamed FF, Ge C, Hallett SA, Bancroft AC, Cowling RT, Ono N, Binrayes AA, Greenberg B, Levi B, Kaartinen VM, Franceschi RT, Control of craniofacial development by the collagen receptor, discoidin domain receptor 2. Elife. 2023 Jan 19;12 |
Ddrgk1 DDRGK domain containing 1 (Synonyms: 1110001I20Rik, 2600009E05Rik) | |
Results | Reference |
1* | J:272566 Yang R, Wang H, Kang B, Chen B, Shi Y, Yang S, Sun L, Liu Y, Xiao W, Zhang T, Yang J, Zhang Y, Zhu M, Xu P, Chang Y, Jia Y, Huang Y, CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235 |
Ddx1 DEAD box helicase 1 (Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 1) | |
Results | Reference |
1* | J:186654 Gao Z, Poon HY, Li L, Li X, Palmesino E, Glubrecht DD, Colwill K, Dutta I, Kania A, Pawson T, Godbout R, Splice-mediated motif switching regulates disabled-1 phosphorylation and SH2 domain interactions. Mol Cell Biol. 2012 Jul;32(14):2794-808 |
Ddx3x DEAD box helicase 3, X-linked (Synonyms: D1Pas1-rs2, Ddx3, DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked, embryonic RNA helicase, Fin14) | |
Results | Reference |
1 | J:231798 Chen CY, Chan CH, Chen CM, Tsai YS, Tsai TY, Wu Lee YH, You LR, Targeted inactivation of murine Ddx3x: essential roles of Ddx3x in placentation and embryogenesis. Hum Mol Genet. 2016 July 15;25(14):2905-2922 |
1 | J:292736 Lennox AL, Hoye ML, Jiang R, Johnson-Kerner BL, Suit LA, Venkataramanan S, Sheehan CJ, Alsina FC, Fregeau B, Aldinger KA, Moey C, Lobach I, Afenjar A, Babovic-Vuksanovic D, Bezieau S, Blackburn PR, Bunt J, Burglen L, Campeau PM, Charles P, Chung BHY, Cogne B, Curry C, D'Agostino MD, Di Donato N, Faivre L, Heron D, Innes AM, Isidor B, Keren B, Kimball A, Klee EW, Kuentz P, Kury S, Martin-Coignard D, Mirzaa G, Mignot C, Miyake N, Matsumoto N, Fujita A, Nava C, Nizon M, Rodriguez D, Blok LS, Thauvin-Robinet C, Thevenon J, Vincent M, Ziegler A, Dobyns W, Richards LJ, Barkovich AJ, Floor SN, Silver DL, Sherr EH, Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development. Neuron. 2020 May 6;106(3):404-420.e8 |
1 | J:296045 Patmore DM, Jassim A, Nathan E, Gilbertson RJ, Tahan D, Hoffmann N, Tong Y, Smith KS, Kanneganti TD, Suzuki H, Taylor MD, Northcott P, Gilbertson RJ, DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma. Dev Cell. 2020 Aug 24;54(4):455-470.e5 |
Ddx4 DEAD box helicase 4 (Synonyms: DEAD (Asp-Glu-Ala-Asp) box polypeptide 4, Mvh, mvh / m'vasa, VASA) | |
Results | Reference |
1* | J:308859 Akter MS, Hada M, Shikata D, Watanabe G, Ogura A, Matoba S, CRISPR/Cas9-based genetic screen of SCNT-reprogramming resistant genes identifies critical genes for male germ cell development in mice. Sci Rep. 2021 Jul 29;11(1):15438 |
1 | J:275626 Anamthathmakula P, Miryala CSJ, Moreci RS, Kyathanahalli C, Hassan SS, Condon JC, Jeyasuria P, Steroidogenic Factor 1 (Nr5a1) is Required for Sertoli Cell Survival Post Sex Determination. Sci Rep. 2019 Mar 14;9(1):4452 |
1* | J:253477 Bailey AS, Batista PJ, Gold RS, Chen YG, de Rooij DG, Chang HY, Fuller MT, The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline. Elife. 2017 Oct 31;6:e26116 |
1 | J:179634 Chassot AA, Gregoire EP, Lavery R, Taketo MM, de Rooij DG, Adams IR, Chaboissier MC, RSPO1/beta-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary. PLoS One. 2011;6(10):e25641 |
1 | J:305337 Chen M, Wang Y, Lin L, Dong F, Wu H, Bao S, Gao F, PRMT7 is involved in regulation of germ cell proliferation during embryonic stage. Biochem Biophys Res Commun. 2020 Dec 17;533(4):938-944 |
1 | J:194489 Chen SR, Chen M, Wang XN, Zhang J, Wen Q, Ji SY, Zheng QS, Gao F, Liu YX, The wilms tumor gene, wt1, maintains testicular cord integrity by regulating the expression of col4a1 and col4a2. Biol Reprod. 2013;88(3):56 |
1 | J:167041 Cook MS, Munger SC, Nadeau JH, Capel B, Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background. Development. 2011 Jan;138(1):23-32 |
1 | J:184034 De Fazio S, Bartonicek N, Di Giacomo M, Abreu-Goodger C, Sankar A, Funaya C, Antony C, Moreira PN, Enright AJ, O'Carroll D, The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements. Nature. 2011 Dec 8;480(7376):259-63 |
1 | J:194500 Deguchi K, Nagamatsu G, Miyachi H, Kato Y, Morita S, Kimura H, Kitano S, Hatada I, Saga Y, Tachibana M, Shinkai Y, Posttranscriptional regulation of histone lysine methyltransferase GLP in embryonic male mouse germ cells. Biol Reprod. 2013 Feb;88(2):36 |
1* | J:21929 Fujiwara Y, Komiya T, Kawabata H, Sato M, Fujimoto H, Furusawa M, Noce T, Isolation of a DEAD-family protein gene that encodes a murine homolog of Drosophila vasa and its specific expression in germ cell lineage. Proc Natl Acad Sci U S A. 1994 Dec 6;91(25):12258-62 |
1* | J:354187 Hayashi Y, Kaneko J, Ito-Matsuoka Y, Takehara A, Funakoshi M, Maezawa S, Shirane K, Furuya S, Matsui Y, Control of epigenomic landscape and development of fetal male germ cells through L-serine metabolism. iScience. 2024 Sep 20;27(9):110702 |
1 | J:208416 Holt JE, Pye V, Boon E, Stewart JL, Garcia-Higuera I, Moreno S, Rodriguez R, Jones KT, McLaughlin EA, The APC/C activator FZR1 is essential for meiotic prophase I in mice. Development. 2014 Mar;141(6):1354-65 |
1 | J:326085 Huang TC, Wang YF, Vazquez-Ferrer E, Theofel I, Requena CE, Hanna CW, Kelsey G, Hajkova P, Sex-specific chromatin remodelling safeguards transcription in germ cells. Nature. 2021 Dec;600(7890):737-742 |
1 | J:203322 Hussain S, Tuorto F, Menon S, Blanco S, Cox C, Flores JV, Watt S, Kudo NR, Lyko F, Frye M, The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiation. Mol Cell Biol. 2013 Apr;33(8):1561-70 |
1 | J:289708 Jiang X, Yin S, Fan S, Bao J, Jiao Y, Ali A, Iqbal F, Xu J, Zhang Y, Shi Q, Npat-dependent programmed Sertoli cell proliferation is indispensable for testis cord development and germ cell mitotic arrest. FASEB J. 2019 Aug;33(8):9075-9086 |
1 | J:219506 Kim S, Gunesdogan U, Zylicz JJ, Hackett JA, Cougot D, Bao S, Lee C, Dietmann S, Allen GE, Sengupta R, Surani MA, PRMT5 protects genomic integrity during global DNA demethylation in primordial germ cells and preimplantation embryos. Mol Cell. 2014 Nov 20;56(4):564-79 |
1* | J:117138 Kimura T, Nakamura T, Murayama K, Umehara H, Yamano N, Watanabe S, Taketo MM, Nakano T, The stabilization of beta-catenin leads to impaired primordial germ cell development via aberrant cell cycle progression. Dev Biol. 2006 Dec 15;300(2):545-53 |
1 | J:82464 Kimura T, Suzuki A, Fujita Y, Yomogida K, Lomeli H, Asada N, Ikeuchi M, Nagy A, Mak TW, Nakano T, Conditional loss of PTEN leads to testicular teratoma and enhances embryonic germ cell production. Development. 2003 Apr;130(8):1691-700 |
1* | J:133713 Kuntz S, Kieffer E, Bianchetti L, Lamoureux N, Fuhrmann G, Viville S, Tex19, a mammalian-specific protein with a restricted expression in pluripotent stem cells and germ line. Stem Cells. 2008 Mar;26(3):734-44 |
2* | J:159518 Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Takamatsu K, Chuma S, Kojima-Kita K, Shiromoto Y, Asada N, Toyoda A, Fujiyama A, Totoki Y, Shibata T, Kimura T, Nakatsuji N, Noce T, Sasaki H, Nakano T, MVH in piRNA processing and gene silencing of retrotransposons. Genes Dev. 2010 May;24(9):887-92 |
2 | J:154048 Li H, MacLean G, Cameron D, Clagett-Dame M, Petkovich M, Cyp26b1 expression in murine Sertoli cells is required to maintain male germ cells in an undifferentiated state during embryogenesis. PLoS One. 2009;4(10):e7501 |
1* | J:173838 Manuylov NL, Zhou B, Ma Q, Fox SC, Pu WT, Tevosian SG, Conditional ablation of Gata4 and Fog2 genes in mice reveals their distinct roles in mammalian sexual differentiation. Dev Biol. 2011 May 15;353(2):229-41 |
1 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1 | J:158526 Naillat F, Prunskaite-Hyyrylainen R, Pietila I, Sormunen R, Jokela T, Shan J, Vainio SJ, Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development. Hum Mol Genet. 2010 Apr 15;19(8):1539-50 |
1 | J:326570 Niu W, Spradling AC, Mouse oocytes develop in cysts with the help of nurse cells. Cell. 2022 Jul 7;185(14):2576-2590.e12 |
1 | J:225677 Pastor WA, Stroud H, Nee K, Liu W, Pezic D, Manakov S, Lee SA, Moissiard G, Zamudio N, Bourc'his D, Aravin AA, Clark AT, Jacobsen SE, MORC1 represses transposable elements in the mouse male germline. Nat Commun. 2014;5:5795 |
1* | J:326026 Prokopuk L, Jarred EG, Blucher RO, McLaughlin EA, Stringer JM, Western PS, An essential role for Polycomb Repressive Complex 2 in the mouse ovary. Reproduction. 2022 Feb 17;163(3):167-182 |
1* | J:241573 Pui HP, Saga Y, Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling. Mech Dev. 2017 Apr;144(Pt B):125-139 |
1* | J:258304 Pui HP, Saga Y, NANOS2 acts as an intrinsic regulator of gonocytes-to-spermatogonia transition in the murine testes. Mech Dev. 2018 Feb;149:27-40 |
1 | J:216158 Rastetter RH, Bernard P, Palmer JS, Chassot AA, Chen H, Western PS, Ramsay RG, Chaboissier MC, Wilhelm D, Marker genes identify three somatic cell types in the fetal mouse ovary. Dev Biol. 2014 Oct 15;394(2):242-52 |
2* | J:231047 Rios-Rojas C, Spiller C, Bowles J, Koopman P, Germ cells influence cord formation and leydig cell gene expression during mouse testis development. Dev Dyn. 2016 Apr;245(4):433-44 |
1* | J:134998 Sarraj MA, Chua HK, Umbers A, Loveland KL, Findlay JK, Stenvers KL, Differential expression of TGFBR3 (betaglycan) in mouse ovary and testis during gonadogenesis. Growth Factors. 2007 Oct;25(5):334-45 |
1 | J:307649 Satirapod C, Wang N, MacDonald JA, Sun M, Woods DC, Tilly JL, Estrogen regulation of germline stem cell differentiation as a mechanism contributing to female reproductive aging. Aging (Albany NY). 2020 Apr 17;12(8):7313-7333 |
1* | J:277128 Shiromoto Y, Kuramochi-Miyagawa S, Nagamori I, Chuma S, Arakawa T, Nishimura T, Hasuwa H, Tachibana T, Ikawa M, Nakano T, GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice. Biol Reprod. 2019 Jul 1;101(1):248-256 |
1* | J:242348 Soh YQS, Mikedis MM, Kojima M, Godfrey AK, de Rooij DG, Page DC, Meioc maintains an extended meiotic prophase I in mice. PLoS Genet. 2017 Apr;13(4):e1006704 |
2* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1* | J:249296 Spiller CM, Wilhelm D, Koopman P, Retinoblastoma 1 protein modulates XY germ cell entry into G1/G0 arrest during fetal development in mice. Biol Reprod. 2010 Feb;82(2):433-43 |
1* | J:180844 Strauss TJ, Castrillon DH, Hammes SR, GATA-like protein-1 (GLP-1) is required for normal germ cell development during embryonic oogenesis. Reproduction. 2011 Feb;141(2):173-81 |
1 | J:230058 Suzuki A, Niimi Y, Shinmyozu K, Zhou Z, Kiso M, Saga Y, Dead end1 is an essential partner of NANOS2 for selective binding of target RNAs in male germ cell development. EMBO Rep. 2016 Jan;17(1):37-46 |
1 | J:123269 Tachibana M, Nozaki M, Takeda N, Shinkai Y, Functional dynamics of H3K9 methylation during meiotic prophase progression. EMBO J. 2007 Jul 25;26(14):3346-59 |
2* | J:299510 Wang JJ, Ge W, Zhai QY, Liu JC, Sun XW, Liu WX, Li L, Lei CZ, Dyce PW, De Felici M, Shen W, Single-cell transcriptome landscape of ovarian cells during primordial follicle assembly in mice. PLoS Biol. 2020 Dec;18(12):e3001025 |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
1* | J:198004 Xu J, Gridley T, Notch2 is required in somatic cells for breakdown of ovarian germ-cell nests and formation of primordial follicles. BMC Biol. 2013;11:13 |
1* | J:109159 Yamaguchi YL, Tanaka SS, Kasa M, Yasuda K, Tam PP, Matsui Y, Expression of low density lipoprotein receptor-related protein 4 (Lrp4) gene in the mouse germ cells. Gene Expr Patterns. 2006 Aug;6(6):607-612 |
1 | J:312461 Yin Y, Zhu L, Li Q, Zhou P, Ma L, Cullin4 E3 Ubiquitin Ligases Regulate Male Gonocyte Migration, Proliferation and Blood-Testis Barrier Homeostasis. Cells. 2021 Oct 13;10(10) |
1 | J:362758 Zhang L, Li Y, Hu Y, Chen M, Cen C, Chen M, Lin L, Zhou J, Wang M, Cui X, Tang F, Gao F, Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression. FASEB J. 2022 Feb;36(2):e22131 |
1 | J:316098 Zhao J, Lu P, Wan C, Huang Y, Cui M, Yang X, Hu Y, Zheng Y, Dong J, Wang M, Zhang S, Liu Z, Bian S, Wang X, Wang R, Ren S, Wang D, Yao Z, Chang G, Tang F, Zhao XY, Cell-fate transition and determination analysis of mouse male germ cells throughout development. Nat Commun. 2021 Nov 25;12(1):6839 |
Ddx5 DEAD box helicase 5 (Synonyms: 2600009A06Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 5, Hlr1, p68) | |
Results | Reference |
1 | J:160411 Joo JH, Kim YH, Dunn NW, Sugrue SP, Disruption of mouse corneal epithelial differentiation by conditional inactivation of pnn. Invest Ophthalmol Vis Sci. 2010 Apr;51(4):1927-34 |
Ddx6 DEAD-box helicase 6 (Synonyms: 1110001P04Rik, C430015D01Rik, DEAD (Asp-Glu-Ala-Asp) box polypeptide 6, E230023J21Rik, HLR2, mRCK/P54, p54, rck) | |
Results | Reference |
1 | J:157579 Suzuki A, Igarashi K, Aisaki K, Kanno J, Saga Y, NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3594-9 |
1 | J:169934 Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A, Hoki Y, Fujiyama A, Shibata T, Sado T, Noce T, Nakano T, Nakatsuji N, Lin H, Sasaki H, MITOPLD Is a Mitochondrial Protein Essential for Nuage Formation and piRNA Biogenesis in the Mouse Germline. Dev Cell. 2011 Mar 15;20(3):364-75 |
Deaf1 DEAF1, transcription factor (Synonyms: C230009B13Rik, NUDR, suppressin) | |
Results | Reference |
1* | J:88168 Hahm K, Sum EY, Fujiwara Y, Lindeman GJ, Visvader JE, Orkin SH, Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1. Mol Cell Biol. 2004 Mar;24(5):2074-82 |
Defa1 defensin, alpha 1 (Synonyms: cryptdin-1, Defcr1) | |
Results | Reference |
1* | J:150374 Garcia MI, Ghiani M, Lefort A, Libert F, Strollo S, Vassart G, LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine. Dev Biol. 2009 Jul 1;331(1):58-67 |
Defa5 defensin, alpha, 5 (Synonyms: Defcr5) | |
Results | Reference |
1* | J:150374 Garcia MI, Ghiani M, Lefort A, Libert F, Strollo S, Vassart G, LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine. Dev Biol. 2009 Jul 1;331(1):58-67 |
Defa29 defensin, alpha, 29 (Synonyms: 2010300L12Rik, 2010319H24Rik, CRS1C-2, Defa-rs1) | |
Results | Reference |
1* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
Defb1 defensin beta 1 (Synonyms: mBD-1) | |
Results | Reference |
1 | J:182938 Sevilla LM, Bayo P, Latorre V, Sanchis A, Perez P, Glucocorticoid receptor regulates overlapping and differential gene subsets in developing and adult skin. Mol Endocrinol. 2010 Nov;24(11):2166-78 |
Defb19 defensin beta 19 (Synonyms: Tdl) | |
Results | Reference |
1* | J:78164 Yamamoto M, Matsui Y, Testis-specific expression of a novel mouse defensin-like gene, Tdl. Mech Dev. 2002 Aug;116(1-2):217-21 |
Degs1 delta 4-desaturase, sphingolipid 1 (Synonyms: Des1, Mdes) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Depp1 DEPP1 autophagy regulator (Synonyms: 8430408G22Rik, Depp) | |
Results | Reference |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
Des desmin | |
Results | Reference |
1 | J:219809 Afelik S, Pool B, Schmerr M, Penton C, Jensen J, Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development. Dev Biol. 2015 Mar 15;399(2):204-17 |
1* | J:74504 Amano O, Yamane A, Shimada M, Koshimizu U, Nakamura T, Iseki S, Hepatocyte growth factor is essential for migration of myogenic cells and promotes their proliferation during the early periods of tongue morphogenesis in mouse embryos. Dev Dyn. 2002 Mar;223(2):169-79 |
1 | J:263978 Ariza L, Canete A, Rojas A, Munoz-Chapuli R, Carmona R, Role of the Wilms' tumor suppressor gene Wt1 in pancreatic development. Dev Dyn. 2018 Apr 30; |
1* | J:84903 Bolcato-Bellemin AL, Lefebvre O, Arnold C, Sorokin L, Miner JH, Kedinger M, Simon-Assmann P, Laminin alpha5 chain is required for intestinal smooth muscle development. Dev Biol. 2003 Aug 15;260(2):376-90 |
1 | J:283675 Comai G, Heude E, Mella S, Paisant S, Pala F, Gallardo M, Langa F, Kardon G, Gopalakrishnan S, Tajbakhsh S, A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle. Elife. 2019 Sep 19;8:e47460 |
1* | J:24100 Dahl E, Winterhager E, Traub O, Willecke K, Expression of gap junction genes, connexin40 and connexin43, during fetal mouse development. Anat Embryol (Berl). 1995 Mar;191(3):267-78 |
1 | J:155846 de Lange FJ, Moorman AF, Anderson RH, Manner J, Soufan AT, de Gier-de Vries C, Schneider MD, Webb S, van den Hoff MJ, Christoffels VM, Lineage and morphogenetic analysis of the cardiac valves. Circ Res. 2004 Sep 17;95(6):645-54 |
1 | J:185218 Hall-Glenn F, De Young RA, Huang BL, van Handel B, Hofmann JJ, Chen TT, Choi A, Ong JR, Benya PD, Mikkola H, Iruela-Arispe ML, Lyons KM, CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PLoS One. 2012;7(2):e30562 |
1 | J:105090 Heimann P, Kuschel T, Jockusch H, Elimination by necrosis, not apoptosis, of embryonic extraocular muscles in the muscular dysgenesis mutant of the mouse. Cell Tissue Res. 2004 Feb;315(2):243-7 |
1 | J:20328 Hellstrom M, Kal n M, Lindahl P, Abramsson A, Betsholtz C, Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development. 1999 Jun;126(14):3047-55 |
1 | J:221983 Heude E, Bellessort B, Fontaine A, Hamazaki M, Treier AC, Treier M, Levi G, Narboux-Neme N, Etiology of craniofacial malformations in mouse models of blepharophimosis, ptosis and epicanthus inversus syndrome. Hum Mol Genet. 2015 Mar 15;24(6):1670-81 |
1 | J:60987 Kablar B, Tajbakhsh S, Rudnicki MA, Transdifferentiation of esophageal smooth to skeletal muscle is myogenic bHLH factor-dependent. Development. 2000 Apr;127(8):1627-39 |
1* | J:98918 Kassar-Duchossoy L, Giacone E, Gayraud-Morel B, Jory A, Gomes D, Tajbakhsh S, Pax3/Pax7 mark a novel population of primitive myogenic cells during development. Genes Dev. 2005 Jun 15;19(12):1426-31 |
1 | J:348423 Kitamura A, Yamamoto M, Hirouchi H, Watanabe G, Taniguchi S, Sekiya S, Ishizuka S, Jeong J, Higa K, Yamashita S, Abe S, Downregulation of SOX9 expression in developing entheses adjacent to intramembranous bone. PLoS One. 2024;19(5):e0301080 |
1* | J:59925 Miner JH, Li C, Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane. Dev Biol. 2000 Jan 15;217(2):278-89 |
1 | J:329397 Nadeem T, Bommareddy A, Bolarinwa L, Cuervo H, Pericyte dynamics in the mouse germinal matrix angiogenesis. FASEB J. 2022 Jun;36(6):e22339 |
1 | J:255459 Nara M, Kitamura K, Yamamoto M, Nagakura R, Mitomo K, Matsunaga S, Abe S, Developmental mechanism of muscle-tendon-bone complex in the fetal soft palate. Arch Oral Biol. 2017 Oct;82:71-78 |
1 | J:263065 Ogawa T, Li Y, Lua I, Hartner A, Asahina K, Isolation of a unique hepatic stellate cell population expressing integrin alpha8 from embryonic mouse livers. Dev Dyn. 2018 Jun;247(6):867-881 |
1 | J:200747 Tonami K, Hata S, Ojima K, Ono Y, Kurihara Y, Amano T, Sato T, Kawamura Y, Kurihara H, Sorimachi H, Calpain-6 deficiency promotes skeletal muscle development and regeneration. PLoS Genet. 2013 Aug;9(8):e1003668 |
1 | J:331473 Tran V, Nahle S, Robert A, Desanlis I, Killoran R, Ehresmann S, Thibault MP, Barford D, Ravichandran KS, Sauvageau M, Smith MJ, Kmita M, Cote JF, Biasing the conformation of ELMO2 reveals that myoblast fusion can be exploited to improve muscle regeneration. Nat Commun. 2022 Nov 18;13(1):7077 |
1* | J:61155 Valdez MR, Richardson JA, Klein WH, Olson EN, Failure of Myf5 to support myogenic differentiation without myogenin, MyoD, and MRF4. Dev Biol. 2000 Mar 15;219(2):287-98 |
1 | J:239983 Walton KD, Whidden M, Kolterud A, Shoffner SK, Czerwinski MJ, Kushwaha J, Parmar N, Chandhrasekhar D, Freddo AM, Schnell S, Gumucio DL, Villification in the mouse: Bmp signals control intestinal villus patterning. Development. 2016 Feb 01;143(3):427-36 |
1 | J:241565 Zhang Q, Vashisht AA, O'Rourke J, Corbel SY, Moran R, Romero A, Miraglia L, Zhang J, Durrant E, Schmedt C, Sampath SC, Sampath SC, The microprotein Minion controls cell fusion and muscle formation. Nat Commun. 2017 Jun 01;8:15664 |
1 | J:163662 Zhang Y, Li S, Yuan L, Tian Y, Weidenfeld J, Yang J, Liu F, Chokas AL, Morrisey EE, Foxp1 coordinates cardiomyocyte proliferation through both cell-autonomous and nonautonomous mechanisms. Genes Dev. 2010 Aug 15;24(16):1746-57 |
Desi2 desumoylating isopeptidase 2 (Synonyms: 5830417C01Rik, Fam152a, Pppde1) | |
Results | Reference |
1* | J:183741 Cai P, Xia X, Li F, Cui Y, Yang Q, Chen M, PNAS4 knockout does not induce obviously neurocytes apoptosis and abnormal development in mice brain. Mol Biol Rep. 2012 Jan;39(1):621-8 |
Deup1 deuterosome assembly protein 1 (Synonyms: 4933401K09Rik, Ccdc67) | |
Results | Reference |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
Dgat1 diacylglycerol O-acyltransferase 1 (Synonyms: D15Ertd23e) | |
Results | Reference |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
Dgat2 diacylglycerol O-acyltransferase 2 (Synonyms: 0610010B06Rik) | |
Results | Reference |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
Dgkd diacylglycerol kinase, delta (Synonyms: dgkd-2, DGKdelta) | |
Results | Reference |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
Dgkq diacylglycerol kinase, theta (Synonyms: 110kDa, Dagk4, DAGK7, Dgkd, Dgk theta) | |
Results | Reference |
1* | J:204604 Ueda S, Tu-Sekine B, Yamanoue M, Raben DM, Shirai Y, The expression of diacylglycerol kinase theta during the organogenesis of mouse embryos. BMC Dev Biol. 2013;13:35 |
Dglucy D-glutamate cyclase (Synonyms: 9030617O03Rik) | |
Results | Reference |
1* | J:241368 Ariyoshi M, Katane M, Hamase K, Miyoshi Y, Nakane M, Hoshino A, Okawa Y, Mita Y, Kaimoto S, Uchihashi M, Fukai K, Ono K, Tateishi S, Hato D, Yamanaka R, Honda S, Fushimura Y, Iwai-Kanai E, Ishihara N, Mita M, Homma H, Matoba S, D-Glutamate is metabolized in the heart mitochondria. Sci Rep. 2017 Mar 07;7:43911 |
Dhcr24 24-dehydrocholesterol reductase (Synonyms: 2310076D10Rik, 3-beta-hydroxysterol delta-24 reductase, 5830417J06Rik, mKIAA0018, seladin-1) | |
Results | Reference |
1* | J:112056 Tint GS, Yu H, Shang Q, Xu G, Patel SB, The use of the Dhcr7 knockout mouse to accurately determine the origin of fetal sterols. J Lipid Res. 2006 Jul;47(7):1535-41 |
Dhh desert hedgehog | |
Results | Reference |
1 | J:152858 Garcia-Ortiz JE, Pelosi E, Omari S, Nedorezov T, Piao Y, Karmazin J, Uda M, Cao A, Cole SW, Forabosco A, Schlessinger D, Ottolenghi C, Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Dev Biol. 2009;9:36 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1* | J:106304 Jeays-Ward K, Dandonneau M, Swain A, Wnt4 is required for proper male as well as female sexual development. Dev Biol. 2004 Dec 15;276(2):431-40 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
1 | J:246806 Li Y, Zhang L, Hu Y, Chen M, Han F, Qin Y, Chen M, Cui X, Duo S, Tang F, Gao F, beta-Catenin directs the transformation of testis Sertoli cells to ovarian granulosa-like cells by inducing Foxl2 expression. J Biol Chem. 2017 Oct 27;292(43):17577-17586 |
1 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1 | J:163175 Rice DP, Connor EC, Veltmaat JM, Lana-Elola E, Veistinen L, Tanimoto Y, Bellusci S, Rice R, Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation. Hum Mol Genet. 2010 Sep 1;19(17):3457-67 |
1 | J:167067 Seidel K, Ahn CP, Lyons D, Nee A, Ting K, Brownell I, Cao T, Carano RA, Curran T, Schober M, Fuchs E, Joyner A, Martin GR, de Sauvage FJ, Klein OD, Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor. Development. 2010 Nov;137(22):3753-61 |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
Dhrs3 dehydrogenase/reductase 3 (Synonyms: dehydrogenase/reductase (SDR family) member 3, retSDR1, Rsdr1) | |
Results | Reference |
1* | J:51222 Bachner D, Ahrens M, Schroder D, Hoffmann A, Lauber J, Betat N, Steinert P, Flohe L, Gross G, Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T1/2). Dev Dyn. 1998 Dec;213(4):398-411 |
Dhx36 DEAH-box helicase 36 (Synonyms: 2810407E23Rik, Ddx36, mKIAA1488, RHAU) | |
Results | Reference |
1* | J:265627 Nie J, Jiang M, Zhang X, Tang H, Jin H, Huang X, Yuan B, Zhang C, Lai JC, Nagamine Y, Pan D, Wang W, Yang Z, Post-transcriptional Regulation of Nkx2-5 by RHAU in Heart Development. Cell Rep. 2015 Oct 27;13(4):723-732 |
Diaph1 diaphanous related formin 1 (Synonyms: D18Wsu154e, Dia1, Diap1, Drf1, mDia1, p140mDia) | |
Results | Reference |
1* | J:244564 Lin Q, Ponnusamy R, Widagdo J, Choi JA, Ge W, Probst C, Buckley T, Lou M, Bredy TW, Fanselow MS, Ye K, Sun YE, MicroRNA-mediated disruption of dendritogenesis during a critical period of development influences cognitive capacity later in life. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9188-9193 |
Diaph2 diaphanous related formin 2 (Synonyms: Dia3, Diap2, E430022I22Rik, mDia3) | |
Results | Reference |
1* | J:332881 Chiereghin C, Robusto M, Lewis MA, Caetano S, Massa V, Castorina P, Ambrosetti U, Steel KP, Duga S, Asselta R, Solda G, In-depth genetic and molecular characterization of diaphanous related formin 2 (DIAPH2) and its role in the inner ear. PLoS One. 2023;18(1):e0273586 |
Dicer1 dicer 1, ribonuclease type III (Synonyms: 1110006F08Rik, D12Ertd7e, Dicer1, mKIAA0928) | |
Results | Reference |
2 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1 | J:294413 Croizier S, Park S, Maillard J, Bouret SG, Central Dicer-miR-103/107 controls developmental switch of POMC progenitors into NPY neurons and impacts glucose homeostasis. Elife. 2018 Oct 12;7:e40429 |
1* | J:203415 Flemr M, Malik R, Franke V, Nejepinska J, Sedlacek R, Vlahovicek K, Svoboda P, A retrotransposon-driven dicer isoform directs endogenous small interfering RNA production in mouse oocytes. Cell. 2013 Nov 7;155(4):807-16 |
1* | J:160269 Michon F, Tummers M, Kyyronen M, Frilander MJ, Thesleff I, Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol. 2010 Apr 15;340(2):355-68 |
1 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
1* | J:239256 Zheng L, Tu Q, Meng S, Zhang L, Yu L, Song J, Hu Y, Sui L, Zhang J, Dard M, Cheng J, Murray D, Tang Y, Lian JB, Stein GS, Chen J, Runx2/DICER/miRNA Pathway in Regulating Osteogenesis. J Cell Physiol. 2017 Jan;232(1):182-91 |
Dio2 deiodinase, iodothyronine, type II | |
Results | Reference |
1 | J:324530 Fonseca TL, Russo SC, Luongo C, Salvatore D, Bianco AC, Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 May 1;163(5) |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
Dio3 deiodinase, iodothyronine type III | |
Results | Reference |
1 | J:324530 Fonseca TL, Russo SC, Luongo C, Salvatore D, Bianco AC, Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 May 1;163(5) |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
1* | J:299191 Kitazawa M, Hayashi S, Imamura M, Takeda S, Oishi Y, Kaneko-Ishino T, Ishino F, Deficiency and overexpression of Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Kagami-Ogata syndromes. Development. 2020 Sep 2;147(21):dev185918 |
1 | J:216177 Labialle S, Marty V, Bortolin-Cavaille ML, Hoareau-Osman M, Pradere JP, Valet P, Martin PG, Cavaille J, The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation. EMBO J. 2014 Oct 1;33(19):2216-30 |
1* | J:218428 Martinez ME, Charalambous M, Saferali A, Fiering S, Naumova AK, St Germain D, Ferguson-Smith AC, Hernandez A, Genomic imprinting variations in the mouse type 3 deiodinase gene between tissues and brain regions. Mol Endocrinol. 2014 Nov;28(11):1875-86 |
1* | J:151815 Ng L, Hernandez A, He W, Ren T, Srinivas M, Ma M, Galton VA, St Germain DL, Forrest D, A protective role for type 3 deiodinase, a thyroid hormone-inactivating enzyme, in cochlear development and auditory function. Endocrinology. 2009 Apr;150(4):1952-60 |
1 | J:159022 Ng L, Lyubarsky A, Nikonov SS, Ma M, Srinivas M, Kefas B, St Germain DL, Hernandez A, Pugh EN Jr, Forrest D, Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors. J Neurosci. 2010 Mar 3;30(9):3347-57 |
1 | J:108133 Sekita Y, Wagatsuma H, Irie M, Kobayashi S, Kohda T, Matsuda J, Yokoyama M, Ogura A, Schuster-Gossler K, Gossler A, Ishino F, Kaneko-Ishino T, Aberrant regulation of imprinted gene expression in Gtl2lacZ mice. Cytogenet Genome Res. 2006;113(1-4):223-9 |
1* | J:166176 Zhou Y, Cheunsuchon P, Nakayama Y, Lawlor MW, Zhong Y, Rice KA, Zhang L, Zhang X, Gordon FE, Lidov HG, Bronson RT, Klibanski A, Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. Development. 2010 Aug;137(16):2643-52 |
Dio3os deiodinase, iodothyronine type III, opposite strand (Synonyms: Dio3as, Dio3os) | |
Results | Reference |
1* | J:105770 Tierling S, Dalbert S, Schoppenhorst S, Tsai CE, Oliger S, Ferguson-Smith AC, Paulsen M, Walter J, High-resolution map and imprinting analysis of the Gtl2-Dnchc1 domain on mouse chromosome 12. Genomics. 2006 Feb;87(2):225-35 |
Dip2a disco interacting protein 2 homolog A (Synonyms: 4931420H10Rik, Dip2, Kiaa0184-hp, mKIAA0184) | |
Results | Reference |
2* | J:280803 Ma J, Zhang LQ, He ZX, He XX, Wang YJ, Jian YL, Wang X, Zhang BB, Su C, Lu J, Huang BQ, Zhang Y, Wang GY, Guo WX, Qiu DL, Mei L, Xiong WC, Zheng YW, Zhu XJ, Autism candidate gene DIP2A regulates spine morphogenesis via acetylation of cortactin. PLoS Biol. 2019 Oct;17(10):e3000461 |
Dipk2a divergent protein kinase domain 2A (Synonyms: 1190002N15Rik, GoPro49) | |
Results | Reference |
1* | J:139013 Takatalo M, Jarvinen E, Laitinen S, Thesleff I, Ronnholm R, Expression of the novel Golgi protein GoPro49 is developmentally regulated during mesenchymal differentiation. Dev Dyn. 2008 Aug;237(8):2243-55 |
Disc1 disrupted in schizophrenia 1 | |
Results | Reference |
1* | J:94923 Schurov IL, Handford EJ, Brandon NJ, Whiting PJ, Expression of disrupted in schizophrenia 1 (DISC1) protein in the adult and developing mouse brain indicates its role in neurodevelopment. Mol Psychiatry. 2004 Dec;9(12):1100-10 |
Disp1 dispatched RND transporter family member 1 (Synonyms: 1190008H24Rik, DispA) | |
Results | Reference |
1* | J:79831 Kawakami T, Kawcak T, Li YJ, Zhang W, Hu Y, Chuang PT, Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling. Development. 2002 Dec;129(24):5753-65 |
Dkc1 dyskeratosis congenita 1, dyskerin | |
Results | Reference |
1* | J:63601 Heiss NS, Bachner D, Salowsky R, Kolb A, Kioschis P, Poustka A, Gene structure and expression of the mouse dyskeratosis congenita gene, dkc1. Genomics. 2000 Jul 15;67(2):153-63 |
Dkk1 dickkopf WNT signaling pathway inhibitor 1 (Synonyms: mdkk-1) | |
Results | Reference |
1 | J:76477 Andl T, Reddy ST, Gaddapara T, Millar SE, WNT Signals Are Required for the Initiation of Hair Follicle Development. Dev Cell. 2002 May;2(5):643-53 |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:254639 Chen L, Martino V, Dombkowski A, Williams T, West-Mays J, Gage PJ, AP-2beta Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development. Invest Ophthalmol Vis Sci. 2016 Mar;57(3):1072-81 |
1 | J:111051 Cui CY, Hashimoto T, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9142-7 |
1* | J:97457 Fjeld K, Kettunen P, Furmanek T, Kvinnsland IH, Luukko K, Dynamic expression of Wnt signaling-related Dickkopf1, -2, and -3 mRNAs in the developing mouse tooth. Dev Dyn. 2005 May;233(1):161-6 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1 | J:178499 Joeng KS, Schumacher CA, Zylstra-Diegel CR, Long F, Williams BO, Lrp5 and Lrp6 redundantly control skeletal development in the mouse embryo. Dev Biol. 2011 Nov 15;359(2):222-9 |
1 | J:143588 Kamiya N, Ye L, Kobayashi T, Mochida Y, Yamauchi M, Kronenberg HM, Feng JQ, Mishina Y, BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development. 2008 Nov;135(22):3801-11 |
1 | J:171428 Li J, Huang X, Xu X, Mayo J, Bringas P Jr, Jiang R, Wang S, Chai Y, SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis. Development. 2011 May;138(10):1977-89 |
1 | J:114081 Li J, Sarosi I, Cattley RC, Pretorius J, Asuncion F, Grisanti M, Morony S, Adamu S, Geng Z, Qiu W, Kostenuik P, Lacey DL, Simonet WS, Bolon B, Qian X, Shalhoub V, Ominsky MS, Zhu Ke H, Li X, Richards WG, Dkk1-mediated inhibition of Wnt signaling in bone results in osteopenia. Bone. 2006 Oct;39(4):754-66 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:153980 Matsushita T, Chan YY, Kawanami A, Balmes G, Landreth GE, Murakami S, Extracellular signal-regulated kinase 1 (ERK1) and ERK2 play essential roles in osteoblast differentiation and in supporting osteoclastogenesis. Mol Cell Biol. 2009 Nov;29(21):5843-57 |
1* | J:173975 Nie X, Dkk1, -2, and -3 expression in mouse craniofacial development. J Mol Histol. 2005 Jun;36(5):367-72 |
1 | J:112197 Nie X, Luukko K, Fjeld K, Kvinnsland IH, Kettunen P, Developmental expression of Dkk1-3 and Mmp9 and apoptosis in cranial base of mice. J Mol Histol. 2005 Sep;36(6-7):419-26 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1* | J:172979 Potter SS, Hartman HA, Kwan KM, Behringer RR, Patterson LT, Laser capture-microarray analysis of Lim1 mutant kidney development. Genesis. 2007 Jul;45(7):432-9 |
1 | J:324528 Qu R, Gupta K, Dong D, Jiang Y, Landa B, Saez C, Strickland G, Levinsohn J, Weng PL, Taketo MM, Kluger Y, Myung P, Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients. Dev Cell. 2022 Apr 25;57(8):1053-1067.e5 |
1 | J:99391 Shu W, Guttentag S, Wang Z, Andl T, Ballard P, Lu MM, Piccolo S, Birchmeier W, Whitsett JA, Millar SE, Morrisey EE, Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung. Dev Biol. 2005 Jul 1;283(1):226-39 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1 | J:144194 Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72 |
1 | J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687 |
Dkk2 dickkopf WNT signaling pathway inhibitor 2 | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1* | J:97457 Fjeld K, Kettunen P, Furmanek T, Kvinnsland IH, Luukko K, Dynamic expression of Wnt signaling-related Dickkopf1, -2, and -3 mRNAs in the developing mouse tooth. Dev Dyn. 2005 May;233(1):161-6 |
1 | J:239666 Hagglund AC, Jones I, Carlsson L, A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development. Dis Model Mech. 2017 Mar 01;10(3):245-257 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:324237 Kajimoto M, Suzuki K, Ueda Y, Fujimoto K, Takeo T, Nakagata N, Hyuga T, Isono K, Yamada G, Androgen/Wnt/beta-catenin signal axis augments cell proliferation of the mouse erectile tissue, corpus cavernosum. Congenit Anom (Kyoto). 2022 May;62(3):123-133 |
1 | J:143588 Kamiya N, Ye L, Kobayashi T, Mochida Y, Yamauchi M, Kronenberg HM, Feng JQ, Mishina Y, BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development. 2008 Nov;135(22):3801-11 |
1 | J:171428 Li J, Huang X, Xu X, Mayo J, Bringas P Jr, Jiang R, Wang S, Chai Y, SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis. Development. 2011 May;138(10):1977-89 |
1* | J:173975 Nie X, Dkk1, -2, and -3 expression in mouse craniofacial development. J Mol Histol. 2005 Jun;36(5):367-72 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
Dkk3 dickkopf WNT signaling pathway inhibitor 3 | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:259892 Campbell DP, Chrysostomou E, Doetzlhofer A, Canonical Notch signaling plays an instructive role in auditory supporting cell development. Sci Rep. 2016 Jan 20;6:19484 |
1* | J:97457 Fjeld K, Kettunen P, Furmanek T, Kvinnsland IH, Luukko K, Dynamic expression of Wnt signaling-related Dickkopf1, -2, and -3 mRNAs in the developing mouse tooth. Dev Dyn. 2005 May;233(1):161-6 |
1 | J:315856 Lu D, Bao D, Dong W, Liu N, Zhang X, Gao S, Ge W, Gao X, Zhang L, Dkk3 prevents familial dilated cardiomyopathy development through Wnt pathway. Lab Invest. 2016 Feb;96(2):239-48 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
Dkk4 dickkopf WNT signaling pathway inhibitor 4 (Synonyms: MGC:25705) | |
Results | Reference |
2 | J:121612 Bazzi H, Fantauzzo KA, Richardson GD, Jahoda CA, Christiano AM, The Wnt inhibitor, Dickkopf 4, is induced by canonical Wnt signaling during ectodermal appendage morphogenesis. Dev Biol. 2007 May 15;305(2):498-507 |
1 | J:111051 Cui CY, Hashimoto T, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9142-7 |
1 | J:217500 Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D, Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60 |
1* | J:347581 Khatif H, Bazzi H, Generation and characterization of a Dkk4-Cre knock-in mouse line. Genesis. 2024 Feb;62(1):e23532 |
1 | J:237499 Sima J, Piao Y, Chen Y, Schlessinger D, Molecular dynamics of Dkk4 modulates Wnt action and regulates meibomian gland development. Development. 2016 Dec 15;143(24):4723-4735 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
Dkkl1 dickkopf-like 1 (Synonyms: mSgy, SGY-1, SGY1, Soggy) | |
Results | Reference |
1* | J:58147 Krupnik VE, Sharp JD, Jiang C, Robison K, Chickering TW, Amaravadi L, Brown DE, Guyot D, Mays G, Leiby K, Chang B, Duong T, Goodearl AD, Gearing DP, Sokol SY, McCarthy SA, Functional and structural diversity of the human Dickkopf gene family. Gene. 1999 Oct 1;238(2):301-13 |
Dlg1 discs large MAGUK scaffold protein 1 (Synonyms: B130052P05Rik, Dlgh1, SAP97) | |
Results | Reference |
1 | J:114313 Naim E, Bernstein A, Bertram JF, Caruana G, Mutagenesis of the epithelial polarity gene, discs large 1, perturbs nephrogenesis in the developing mouse kidney. Kidney Int. 2005 Sep;68(3):955-65 |
Dlg4 discs large MAGUK scaffold protein 4 (Synonyms: Dlgh4, PSD-95, PSD95, SAP90, SAP90A) | |
Results | Reference |
1 | J:250166 Liu K, Lei R, Li Q, Wang XX, Wu Q, An P, Zhang J, Zhu M, Xu Z, Hong Y, Wang F, Shen Y, Li H, Li H, Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity. Sci Rep. 2016 Feb 16;6:21019 |
1 | J:178882 Odajima J, Wills ZP, Ndassa YM, Terunuma M, Kretschmannova K, Deeb TZ, Geng Y, Gawrzak S, Quadros IM, Newman J, Das M, Jecrois ME, Yu Q, Li N, Bienvenu F, Moss SJ, Greenberg ME, Marto JA, Sicinski P, Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation. Dev Cell. 2011 Oct 18;21(4):655-68 |
1 | J:97490 Porter K, Komiyama NH, Vitalis T, Kind PC, Grant SG, Differential expression of two NMDA receptor interacting proteins, PSD-95 and SynGAP during mouse development. Eur J Neurosci. 2005 Jan;21(2):351-62 |
Dlgap4 DLG associated protein 4 (Synonyms: DAP4, MGC:37636, mKIAA0964, PSD-95/SAP90 binding protein 4, SAP90/PSD-95-associated protein 4, Sapap4, WBP16) | |
Results | Reference |
1* | J:325117 Romero DM, Poirier K, Belvindrah R, Moutkine I, Houllier A, LeMoing AG, Petit F, Boland A, Collins SC, Soiza-Reilly M, Yalcin B, Chelly J, Deleuze JF, Bahi-Buisson N, Francis F, Novel role of the synaptic scaffold protein Dlgap4 in ventricular surface integrity and neuronal migration during cortical development. Nat Commun. 2022 May 18;13(1):2746 |
Dlgap5 DLG associated protein 5 (Synonyms: C86398, Dlg7, Hurp, mKIAA0008) | |
Results | Reference |
1* | J:142315 Tsai CY, Chou CK, Yang CW, Lai YC, Liang CC, Chen CM, Tsai TF, Hurp deficiency in mice leads to female infertility caused by an implantation defect. J Biol Chem. 2008 Sep 26;283(39):26302-6 |
Dlk1 delta like non-canonical Notch ligand 1 (Synonyms: DlkI, FA1, Peg9, pG2, pref-1, SCP1, ZOG) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1* | J:176749 Chen L, Qanie D, Jafari A, Taipaleenmaki H, Jensen CH, Saamanen AM, Sanz ML, Laborda J, Abdallah BM, Kassem M, Delta-like 1/fetal antigen-1 (Dlk1/FA1) is a novel regulator of chondrogenic cell differentiation via inhibition of the Akt kinase-dependent pathway. J Biol Chem. 2011 Sep 16;286(37):32140-9 |
1 | J:262635 Drake KA, Adam M, Mahoney R, Potter SS, Disruption of Hox9,10,11 function results in cellular level lineage infidelity in the kidney. Sci Rep. 2018 Apr 20;8(1):6306 |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
3 | J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109 |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
2* | J:277716 Garcia-Gallastegi P, Ruiz-Garcia A, Ibarretxe G, Rivero-Hinojosa S, Gonzalez-Siccha AD, Laborda J, Crende O, Unda F, Garcia-Ramirez JJ, Similarities and differences in tissue distribution of DLK1 and DLK2 during E16.5 mouse embryogenesis. Histochem Cell Biol. 2019 Jul;152(1):47-60 |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:218430 Kamimura S, Hatanaka Y, Hirasawa R, Matsumoto K, Oikawa M, Lee J, Matoba S, Mizutani E, Ogonuki N, Inoue K, Kohda T, Ishino F, Ogura A, Establishment of paternal genomic imprinting in mouse prospermatogonia analyzed by nuclear transfer. Biol Reprod. 2014 Nov;91(5):120 |
1* | J:299191 Kitazawa M, Hayashi S, Imamura M, Takeda S, Oishi Y, Kaneko-Ishino T, Ishino F, Deficiency and overexpression of Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Kagami-Ogata syndromes. Development. 2020 Sep 2;147(21):dev185918 |
1 | J:216177 Labialle S, Marty V, Bortolin-Cavaille ML, Hoareau-Osman M, Pradere JP, Valet P, Martin PG, Cavaille J, The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation. EMBO J. 2014 Oct 1;33(19):2216-30 |
1 | J:294283 Liang Q, Zheng Q, Zuo Y, Chen Y, Ma J, Ni P, Cheng J, SENP2 Suppresses Necdin Expression to Promote Brown Adipocyte Differentiation. Cell Rep. 2019 Aug 20;28(8):2004-2011.e4 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:108133 Sekita Y, Wagatsuma H, Irie M, Kobayashi S, Kohda T, Matsuda J, Yokoyama M, Ogura A, Schuster-Gossler K, Gossler A, Ishino F, Kaneko-Ishino T, Aberrant regulation of imprinted gene expression in Gtl2lacZ mice. Cytogenet Genome Res. 2006;113(1-4):223-9 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:21435 Smas CM, Sul HS, Pref-1, a protein containing EGF-like repeats, inhibits adipocyte differentiation. Cell. 1993 May 21;73(4):725-34 |
1* | J:83345 Tanimizu N, Nishikawa M, Saito H, Tsujimura T, Miyajima A, Isolation of hepatoblasts based on the expression of Dlk/Pref-1. J Cell Sci. 2003 May 1;116(Pt 9):1775-86 |
1 | J:320173 Traustadottir GA, Jensen CH, Thomassen M, Beck HC, Mortensen SB, Laborda J, Baladron V, Sheikh SP, Andersen DC, Evidence of non-canonical NOTCH signaling: Delta-like 1 homolog (DLK1) directly interacts with the NOTCH1 receptor in mammals. Cell Signal. 2016 Apr;28(4):246-54 |
1 | J:356826 Wuelling M, Neu C, Thiesen AM, Kitanovski S, Cao Y, Lange A, Westendorf AM, Hoffmann D, Vortkamp A, Epigenetic Mechanisms Mediating Cell State Transitions in Chondrocytes. J Bone Miner Res. 2021 May;36(5):968-985 |
1* | J:272566 Yang R, Wang H, Kang B, Chen B, Shi Y, Yang S, Sun L, Liu Y, Xiao W, Zhang T, Yang J, Zhang Y, Zhu M, Xu P, Chang Y, Jia Y, Huang Y, CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235 |
2 | J:107205 Yevtodiyenko A, Schmidt JV, Dlk1 expression marks developing endothelium and sites of branching morphogenesis in the mouse embryo and placenta. Dev Dyn. 2006 Apr;235(4):1115-23 |
1* | J:166176 Zhou Y, Cheunsuchon P, Nakayama Y, Lawlor MW, Zhong Y, Rice KA, Zhang L, Zhang X, Gordon FE, Lidov HG, Bronson RT, Klibanski A, Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. Development. 2010 Aug;137(16):2643-52 |
Dlk2 delta like non-canonical Notch ligand 2 (Synonyms: Egfl9) | |
Results | Reference |
2* | J:277716 Garcia-Gallastegi P, Ruiz-Garcia A, Ibarretxe G, Rivero-Hinojosa S, Gonzalez-Siccha AD, Laborda J, Crende O, Unda F, Garcia-Ramirez JJ, Similarities and differences in tissue distribution of DLK1 and DLK2 during E16.5 mouse embryogenesis. Histochem Cell Biol. 2019 Jul;152(1):47-60 |
1* | J:259674 Xu W, Wang Y, Zhao H, Fan B, Guo K, Cai M, Zhang S, Delta-like 2 negatively regulates chondrogenic differentiation. J Cell Physiol. 2018 Sep;233(9):6574-6582 |
Dll1 delta like canonical Notch ligand 1 (Synonyms: Delta1) | |
Results | Reference |
1 | J:213529 Braune EB, Schuster-Gossler K, Lyszkiewicz M, Serth K, Preusse K, Madlung J, Macek B, Krueger A, Gossler A, S/T phosphorylation of DLL1 is required for full ligand activity in vitro but dispensable for DLL1 function in vivo during embryonic patterning and marginal zone B cell development. Mol Cell Biol. 2014 Apr;34(7):1221-33 |
1 | J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489 |
1 | J:63320 Favier B, Fliniaux I, Thelu J, Viallet JP, Demarchez M, Jahoda CA, Dhouailly D, Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators. Dev Dyn. 2000 Jul;218(3):426-37 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1 | J:183603 Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A, Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res. 2011 Apr 1;108(7):813-23 |
1 | J:104840 Grishina IB, Kim SY, Ferrara C, Makarenkova HP, Walden PD, BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling. Dev Biol. 2005 Dec 15;288(2):334-47 |
1 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
2 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:64088 Ito T, Udaka N, Yazawa T, Okudela K, Hayashi H, Sudo T, Guillemot F, Kageyama R, Kitamura H, Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development. 2000 Sep;127(18):3913-21 |
1 | J:143172 Kawaguchi D, Yoshimatsu T, Hozumi K, Gotoh Y, Selection of differentiating cells by different levels of delta-like 1 among neural precursor cells in the developing mouse telencephalon. Development. 2008 Dec;135(23):3849-58 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1* | J:67157 McCright B, Gao X, Shen L, Lozier J, Lan Y, Maguire M, Herzlinger D, Weinmaster G, Jiang R, Gridley T, Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development. 2001 Feb;128(4):491-502 |
1 | J:51928 Mitsiadis TA, Hirsinger E, Lendahl U, Goridis C, Delta-notch signaling in odontogenesis: correlation with cytodifferentiation and evidence for feedback regulation. Dev Biol. 1998 Dec 15;204(2):420-31 |
1* | J:56415 Morrison A, Hodgetts C, Gossler A, Hrabe de Angelis M, Lewis J, Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear. Mech Dev. 1999 Jun;84(1-2):169-72 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
2 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:330615 Rim JH, Noh B, Koh YI, Joo SY, Oh KS, Kim K, Kim JA, Kim DH, Kim HY, Yoo JE, Lee ST, Bok JW, Lee MG, Jung J, Choi JY, Gee HY, Differential genetic diagnoses of adult post-lingual hearing loss according to the audiogram pattern and novel candidate gene evaluation. Hum Genet. 2022 Apr;141(3-4):915-927 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1 | J:213069 Vanorny DA, Prasasya RD, Chalpe AJ, Kilen SM, Mayo KE, Notch signaling regulates ovarian follicle formation and coordinates follicular growth. Mol Endocrinol. 2014 Apr;28(4):499-511 |
1 | J:110232 Yoshimatsu T, Kawaguchi D, Oishi K, Takeda K, Akira S, Masuyama N, Gotoh Y, Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex. Development. 2006 Jul;133(13):2553-63 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Dll3 delta like canonical Notch ligand 3 | |
Results | Reference |
1 | J:63320 Favier B, Fliniaux I, Thelu J, Viallet JP, Demarchez M, Jahoda CA, Dhouailly D, Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators. Dev Dyn. 2000 Jul;218(3):426-37 |
1 | J:44591 Garel S, Marin F, Grosschedl R, Charnay P, Ebf1 controls early cell differentiation in the embryonic striatum. Development. 1999 Dec;126(23):5285-94 |
1 | J:183603 Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A, Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res. 2011 Apr 1;108(7):813-23 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1* | J:67157 McCright B, Gao X, Shen L, Lozier J, Lan Y, Maguire M, Herzlinger D, Weinmaster G, Jiang R, Gridley T, Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development. 2001 Feb;128(4):491-502 |
1 | J:213069 Vanorny DA, Prasasya RD, Chalpe AJ, Kilen SM, Mayo KE, Notch signaling regulates ovarian follicle formation and coordinates follicular growth. Mol Endocrinol. 2014 Apr;28(4):499-511 |
Dll4 delta like canonical Notch ligand 4 (Synonyms: Delta4) | |
Results | Reference |
1* | J:99531 Benedito R, Duarte A, Expression of Dll4 during mouse embryogenesis suggests multiple developmental roles. Gene Expr Patterns. 2005 Aug;5(6):750-5 |
1 | J:196361 Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnani MG, Messina G, Cossu G, Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory. Dev Cell. 2013 Mar 25;24(6):586-99 |
1 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1 | J:308918 Geng X, Yanagida K, Akwii RG, Choi D, Chen L, Ho Y, Cha B, Mahamud MR, Berman de Ruiz K, Ichise H, Chen H, Wythe JD, Mikelis CM, Hla T, Srinivasan RS, S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling. JCI Insight. 2020 Jul 23;5(14) |
1 | J:183603 Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A, Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res. 2011 Apr 1;108(7):813-23 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:317975 Lu P, Wang Y, Liu Y, Wang Y, Wu B, Zheng D, Harvey RP, Zhou B, Perinatal angiogenesis from pre-existing coronary vessels via DLL4-NOTCH1 signalling. Nat Cell Biol. 2021 Sep;23(9):967-977 |
1* | J:73841 Mailhos C, Modlich U, Lewis J, Harris A, Bicknell R, Ish-Horowicz D, Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis. Differentiation. 2001 Dec;69(2-3):135-44 |
1 | J:65693 Rao PK, Dorsch M, Chickering T, Zheng G, Jiang C, Goodearl A, Kadesch T, McCarthy S, Isolation and characterization of the notch ligand delta4. Exp Cell Res. 2000 Nov 1;260(2):379-86 |
2 | J:299728 Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL, Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. Elife. 2019 Dec 4;8:e49977 |
1 | J:213069 Vanorny DA, Prasasya RD, Chalpe AJ, Kilen SM, Mayo KE, Notch signaling regulates ovarian follicle formation and coordinates follicular growth. Mol Endocrinol. 2014 Apr;28(4):499-511 |
2 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:193198 Wu B, Zhang Z, Lui W, Chen X, Wang Y, Chamberlain AA, Moreno-Rodriguez RA, Markwald RR, O'Rourke BP, Sharp DJ, Zheng D, Lenz J, Baldwin HS, Chang CP, Zhou B, Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling. Cell. 2012 Nov 21;151(5):1083-96 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Dlx1 distal-less homeobox 1 (Synonyms: DII B, Dlx, Dlx-1) | |
Results | Reference |
1* | J:66790 Anderson SA, Marin O, Horn C, Jennings K, Rubenstein JL, Distinct cortical migrations from the medial and lateral ganglionic eminences. Development. 2001 Feb;128(3):353-63 |
1 | J:286635 Chen SY, Lu KM, Ko HA, Huang TH, Hao JH, Yan YT, Chang SL, Evans SM, Liu FC, Parcellation of the striatal complex into dorsal and ventral districts. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7418-7429 |
1 | J:95327 de Melo J, Du G, Fonseca M, Gillespie LA, Turk WJ, Rubenstein JL, Eisenstat DD, Dlx1 and Dlx2 function is necessary for terminal differentiation and survival of late-born retinal ganglion cells in the developing mouse retina. Development. 2005 Jan;132(2):311-22 |
1 | J:44591 Garel S, Marin F, Grosschedl R, Charnay P, Ebf1 controls early cell differentiation in the embryonic striatum. Development. 1999 Dec;126(23):5285-94 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:82656 Hevner RF, Neogi T, Englund C, Daza RA, Fink A, Cajal-Retzius cells in the mouse: transcription factors, neurotransmitters, and birthdays suggest a pallial origin. Brain Res Dev Brain Res. 2003 Mar 14;141(1-2):39-53 |
1 | J:99239 Kroll TT, O'Leary DD, Ventralized dorsal telencephalic progenitors in Pax6 mutant mice generate GABA interneurons of a lateral ganglionic eminence fate. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7374-9 |
1* | J:123566 Le TN, Du G, Fonseca M, Zhou QP, Wigle JT, Eisenstat DD, Dlx homeobox genes promote cortical interneuron migration from the basal forebrain by direct repression of the semaphorin receptor neuropilin-2. J Biol Chem. 2007 Jun 29;282(26):19071-81 |
2 | J:263715 Lee B, Kim J, An T, Kim S, Patel EM, Raber J, Lee SK, Lee S, Lee JW, Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons. Nat Commun. 2018 May 23;9(1):2026 |
1 | J:244498 Lee B, Lee M, Song S, Loi LD, Lam DT, Yoon J, Baek K, Curtis DJ, Jeong Y, Specification of neurotransmitter identity by Tal1 in thalamic nuclei. Dev Dyn. 2017 Oct;246(10):749-758 |
1 | J:237344 Lee B, Lee S, Lee SK, Lee JW, The LIM-homeobox transcription factor Isl1 plays crucial roles in the development of multiple arcuate nucleus neurons. Development. 2016 Oct 15;143(20):3763-3773 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1 | J:240536 Martin-Ibanez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Garcia-Diaz Barriga G, Edel MJ, Vicario-Abejon C, Alberch J, Girault JA, Chan S, Kastner P, Canals JM, Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017 Apr 15;144(8):1566-1577 |
1 | J:151894 Oishi K, Watatani K, Itoh Y, Okano H, Guillemot F, Nakajima K, Gotoh Y, Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):13064-9 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:218837 Song H, Lee B, Pyun D, Guimera J, Son Y, Yoon J, Baek K, Wurst W, Jeong Y, Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation. Dev Biol. 2015 Feb 15;398(2):280-91 |
1* | J:64588 Toresson H, Potter SS, Campbell K, Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for pax6 and gsh2. Development. 2000 Oct;127(20):4361-71 |
1* | J:287411 Tran HN, Park W, Seong S, Jeong JE, Nguyen QH, Yoon J, Baek K, Jeong Y, Tcf7l2 transcription factor is required for the maintenance, but not the initial specification, of the neurotransmitter identity in the caudal thalamus. Dev Dyn. 2020 May;249(5):646-655 |
1 | J:159849 Wang Y, Dye CA, Sohal V, Long JE, Estrada RC, Roztocil T, Lufkin T, Deisseroth K, Baraban SC, Rubenstein JL, Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneurons. J Neurosci. 2010 Apr 14;30(15):5334-45 |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
1 | J:89175 Woodside KJ, Shen H, Muntzel C, Daller JA, Sommers CL, Love PE, Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes. Gene Expr Patterns. 2004 May;4(3):315-20 |
1 | J:264125 Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z, SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. Development. 2018 Jul 23;145(14):dev165456 |
1 | J:329949 Yuan H, Xie B, Yu X, Lin C, Li M, Zhang Y, Zou X, Lu M, Zhao M, Wen X, A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development. Front Physiol. 2022;13:981311 |
2 | J:312485 Zhang Q, Zhang L, Huang Y, Ma P, Mao B, Ding YQ, Song NN, Satb2 regulates the development of dopaminergic neurons in the arcuate nucleus by Dlx1. Cell Death Dis. 2021 Sep 25;12(10):879 |
1* | J:62179 Zhao Z, Stock D, Buchanan A, Weiss K, Expression of Dlx genes during the development of the murine dentition. Dev Genes Evol. 2000 May;210(5):270-5 |
Dlx2 distal-less homeobox 2 (Synonyms: DII A, Dlx-2, Tes-1) | |
Results | Reference |
1 | J:114919 Carney RS, Alfonso TB, Cohen D, Dai H, Nery S, Stoica B, Slotkin J, Bregman BS, Fishell G, Corbin JG, Cell migration along the lateral cortical stream to the developing basal telencephalic limbic system. J Neurosci. 2006 Nov 8;26(45):11562-74 |
1 | J:286635 Chen SY, Lu KM, Ko HA, Huang TH, Hao JH, Yan YT, Chang SL, Evans SM, Liu FC, Parcellation of the striatal complex into dorsal and ventral districts. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7418-7429 |
1 | J:95327 de Melo J, Du G, Fonseca M, Gillespie LA, Turk WJ, Rubenstein JL, Eisenstat DD, Dlx1 and Dlx2 function is necessary for terminal differentiation and survival of late-born retinal ganglion cells in the developing mouse retina. Development. 2005 Jan;132(2):311-22 |
1 | J:172162 de Melo J, Zhou QP, Zhang Q, Zhang S, Fonseca M, Wigle JT, Eisenstat DD, Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development. Nucleic Acids Res. 2008 Feb;36(3):872-84 |
1* | J:125023 French CA, Groszer M, Preece C, Coupe AM, Rajewsky K, Fisher SE, Generation of mice with a conditional Foxp2 null allele. Genesis. 2007 Jul;45(7):440-6 |
2 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:293063 Hamashima T, Ishii Y, Nguyen LQ, Okuno N, Sang Y, Matsushima T, Kurashige Y, Takebayashi H, Mori H, Fujimori T, Yamamoto S, Sasahara M, Oligodendrogenesis and Myelin Formation in the Forebrain Require Platelet-derived Growth Factor Receptor-alpha. Neuroscience. 2020 Jun 1;436:11-26 |
1 | J:81763 Hebert JM, Lin M, Partanen J, Rossant J, McConnell SK, FGF signaling through FGFR1 is required for olfactory bulb morphogenesis. Development. 2003 Mar;130(6):1101-11 |
1 | J:82656 Hevner RF, Neogi T, Englund C, Daza RA, Fink A, Cajal-Retzius cells in the mouse: transcription factors, neurotransmitters, and birthdays suggest a pallial origin. Brain Res Dev Brain Res. 2003 Mar 14;141(1-2):39-53 |
1 | J:336092 Knowles SJ, Stafford AM, Zaman T, Angara K, Williams MR, Newbern JM, Vogt D, Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs. Development. 2023 May 15;150(10):dev201371 |
1 | J:99239 Kroll TT, O'Leary DD, Ventralized dorsal telencephalic progenitors in Pax6 mutant mice generate GABA interneurons of a lateral ganglionic eminence fate. Proc Natl Acad Sci U S A. 2005 May 17;102(20):7374-9 |
2* | J:127151 Kwakowsky A, Schwirtlich M, Zhang Q, Eisenstat DD, Erdelyi F, Baranyi M, Katarova ZD, Szabo G, GAD isoforms exhibit distinct spatiotemporal expression patterns in the developing mouse lens: Correlation with Dlx2 and Dlx5. Dev Dyn. 2007 Dec;236(12):3532-44 |
1* | J:123566 Le TN, Du G, Fonseca M, Zhou QP, Wigle JT, Eisenstat DD, Dlx homeobox genes promote cortical interneuron migration from the basal forebrain by direct repression of the semaphorin receptor neuropilin-2. J Biol Chem. 2007 Jun 29;282(26):19071-81 |
1 | J:263715 Lee B, Kim J, An T, Kim S, Patel EM, Raber J, Lee SK, Lee S, Lee JW, Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons. Nat Commun. 2018 May 23;9(1):2026 |
1 | J:240536 Martin-Ibanez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Garcia-Diaz Barriga G, Edel MJ, Vicario-Abejon C, Alberch J, Girault JA, Chan S, Kastner P, Canals JM, Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017 Apr 15;144(8):1566-1577 |
1* | J:102348 Nery S, Corbin JG, Fishell G, Dlx2 progenitor migration in wild type and Nkx2.1 mutant telencephalon. Cereb Cortex. 2003 Sep;13(9):895-903 |
1* | J:66506 Pleasure SJ, Anderson S, Hevner R, Bagri A, Marin O, Lowenstein DH, Rubenstein JL, Cell migration from the ganglionic eminences is required for the development of hippocampal GABAergic interneurons. Neuron. 2000 Dec;28(3):727-40 |
1* | J:2278 Porteus MH, Brice AE, Bulfone A, Usdin TB, Ciaranello RD, Rubenstein JL, Isolation and characterization of a library of cDNA clones that are preferentially expressed in the embryonic telencephalon. Brain Res Mol Brain Res. 1992 Jan;12(1-3):7-22 |
1* | J:21409 Porteus MH, Bulfone A, Liu JK, Puelles L, Lo LC, Rubenstein JL, DLX-2, MASH-1, and MAP-2 expression and bromodeoxyuridine incorporation define molecularly distinct cell populations in the embryonic mouse forebrain. J Neurosci. 1994 Nov;14(11 Pt 1):6370-83 |
1* | J:22210 Robinson GW, Mahon KA, Differential and overlapping expression domains of Dlx-2 and Dlx-3 suggest distinct roles for Distal-less homeobox genes in craniofacial development. Mech Dev. 1994 Dec;48(3):199-215 |
1* | J:639 Robinson GW, Wray S, Mahon KA, Spatially restricted expression of a member of a new family of murine Distal-less homeobox genes in the developing forebrain. New Biol. 1991 Dec;3(12):1183-94 |
1 | J:168035 Shikata Y, Okada T, Hashimoto M, Ellis T, Matsumaru D, Shiroishi T, Ogawa M, Wainwright B, Motoyama J, Ptch1-mediated dosage-dependent action of Shh signaling regulates neural progenitor development at late gestational stages. Dev Biol. 2011 Jan 15;349(2):147-59 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1* | J:30205 Thomas BL, Porteus MH, Rubenstein JL, Sharpe PT, The spatial localization of Dlx-2 during tooth development. Connect Tissue Res. 1995;32(1-4):27-34 |
1* | J:64588 Toresson H, Potter SS, Campbell K, Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for pax6 and gsh2. Development. 2000 Oct;127(20):4361-71 |
1 | J:86254 Vyas A, Saha B, Lai E, Tole S, Paleocortex is specified in mice in which dorsal telencephalic patterning is severely disrupted. J Comp Neurol. 2003 Nov 24;466(4):545-53 |
1 | J:238248 Wang L, Hou S, Han YG, Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex. Nat Neurosci. 2016 Jul;19(7):888-96 |
1 | J:159849 Wang Y, Dye CA, Sohal V, Long JE, Estrada RC, Roztocil T, Lufkin T, Deisseroth K, Baraban SC, Rubenstein JL, Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneurons. J Neurosci. 2010 Apr 14;30(15):5334-45 |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
1 | J:89175 Woodside KJ, Shen H, Muntzel C, Daller JA, Sommers CL, Love PE, Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes. Gene Expr Patterns. 2004 May;4(3):315-20 |
1 | J:264125 Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z, SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. Development. 2018 Jul 23;145(14):dev165456 |
1 | J:270427 Yabut OR, Fernandez G, Huynh T, Yoon K, Pleasure SJ, Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis. Cell Rep. 2015 Sep 29;12(12):2021-34 |
1 | J:241572 Zhang Q, Zagozewski J, Cheng S, Dixit R, Zhang S, de Melo J, Mu X, Klein WH, Brown NL, Wigle JT, Schuurmans C, Eisenstat DD, Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina. Development. 2017 May 01;144(9):1698-1711 |
1* | J:62179 Zhao Z, Stock D, Buchanan A, Weiss K, Expression of Dlx genes during the development of the murine dentition. Dev Genes Evol. 2000 May;210(5):270-5 |
Dlx3 distal-less homeobox 3 (Synonyms: Dlx-3) | |
Results | Reference |
1 | J:225092 Duverger O, Isaac J, Zah A, Hwang J, Berdal A, Lian JB, Morasso MI, In vivo impact of Dlx3 conditional inactivation in neural crest-derived craniofacial bones. J Cell Physiol. 2013 Mar;228(3):654-64 |
1 | J:104509 Ghoul-Mazgar S, Hotton D, Lezot F, Blin-Wakkach C, Asselin A, Sautier JM, Berdal A, Expression pattern of Dlx3 during cell differentiation in mineralized tissues. Bone. 2005 Dec;37(6):799-809 |
2 | J:140203 Hwang J, Mehrani T, Millar SE, Morasso MI, Dlx3 is a crucial regulator of hair follicle differentiation and cycling. Development. 2008 Sep;135(18):3149-59 |
1* | J:230169 Isaac J, Erthal J, Gordon J, Duverger O, Sun HW, Lichtler AC, Stein GS, Lian JB, Morasso MI, DLX3 regulates bone mass by targeting genes supporting osteoblast differentiation and mineral homeostasis in vivo. Cell Death Differ. 2014 Sep;21(9):1365-76 |
1* | J:52247 Morasso MI, Grinberg A, Robinson G, Sargent TD, Mahon KA, Placental failure in mice lacking the homeobox gene Dlx3. Proc Natl Acad Sci U S A. 1999 Jan 5;96(1):162-7 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
2* | J:22210 Robinson GW, Mahon KA, Differential and overlapping expression domains of Dlx-2 and Dlx-3 suggest distinct roles for Distal-less homeobox genes in craniofacial development. Mech Dev. 1994 Dec;48(3):199-215 |
1 | J:89175 Woodside KJ, Shen H, Muntzel C, Daller JA, Sommers CL, Love PE, Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes. Gene Expr Patterns. 2004 May;4(3):315-20 |
1* | J:62179 Zhao Z, Stock D, Buchanan A, Weiss K, Expression of Dlx genes during the development of the murine dentition. Dev Genes Evol. 2000 May;210(5):270-5 |
Dlx4 distal-less homeobox 4 (Synonyms: DII D, Dlx-4, Dlx7) | |
Results | Reference |
1* | J:62179 Zhao Z, Stock D, Buchanan A, Weiss K, Expression of Dlx genes during the development of the murine dentition. Dev Genes Evol. 2000 May;210(5):270-5 |
Dlx5 distal-less homeobox 5 | |
Results | Reference |
1 | J:56557 Acampora D, Merlo GR, Paleari L, Zerega B, Postiglione MP, Mantero S, Bober E, Barbieri O, Simeone A, Levi G, Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5. Development. 1999 Sep;126(17):3795-809 |
1 | J:307093 Amato CM, Yao HH, Developmental and sexual dimorphic atlas of the prenatal mouse external genitalia at the single-cell level. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2103856118 |
1 | J:227622 Bellessort B, Le Cardinal M, Bachelot A, Narboux-Neme N, Garagnani P, Pirazzini C, Barbieri O, Mastracci L, Jonchere V, Duvernois-Berthet E, Fontaine A, Alfama G, Levi G, Dlx5 and Dlx6 control uterine adenogenesis during post-natal maturation: possible consequences for endometriosis. Hum Mol Genet. 2016 Jan 1;25(1):97-108 |
1* | J:85724 Bendall AJ, Hu G, Levi G, Abate-Shen C, Dlx5 regulates chondrocyte differentiation at multiple stages. Int J Dev Biol. 2003 Jun;47(5):335-44 |
1 | J:286635 Chen SY, Lu KM, Ko HA, Huang TH, Hao JH, Yan YT, Chang SL, Evans SM, Liu FC, Parcellation of the striatal complex into dorsal and ventral districts. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7418-7429 |
1 | J:304355 Garcia-Calero E, Lopez-Gonzalez L, Martinez-de-la-Torre M, Fan CM, Puelles L, Sim1-expressing cells illuminate the origin and course of migration of the nucleus of the lateral olfactory tract in the mouse amygdala. Brain Struct Funct. 2021 Mar;226(2):519-562 |
1 | J:163224 Garcia-Lopez M, Abellan A, Legaz I, Rubenstein JL, Puelles L, Medina L, Histogenetic compartments of the mouse centromedial and extended amygdala based on gene expression patterns during development. J Comp Neurol. 2008 Jan 1;506(1):46-74 |
1 | J:44591 Garel S, Marin F, Grosschedl R, Charnay P, Ebf1 controls early cell differentiation in the embryonic striatum. Development. 1999 Dec;126(23):5285-94 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:82656 Hevner RF, Neogi T, Englund C, Daza RA, Fink A, Cajal-Retzius cells in the mouse: transcription factors, neurotransmitters, and birthdays suggest a pallial origin. Brain Res Dev Brain Res. 2003 Mar 14;141(1-2):39-53 |
1* | J:127151 Kwakowsky A, Schwirtlich M, Zhang Q, Eisenstat DD, Erdelyi F, Baranyi M, Katarova ZD, Szabo G, GAD isoforms exhibit distinct spatiotemporal expression patterns in the developing mouse lens: Correlation with Dlx2 and Dlx5. Dev Dyn. 2007 Dec;236(12):3532-44 |
1 | J:83383 Levi G, Puche AC, Mantero S, Barbieri O, Trombino S, Paleari L, Egeo A, Merlo GR, The Dlx5 homeodomain gene is essential for olfactory development and connectivity in the mouse. Mol Cell Neurosci. 2003 Apr;22(4):530-43 |
1 | J:240536 Martin-Ibanez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Garcia-Diaz Barriga G, Edel MJ, Vicario-Abejon C, Alberch J, Girault JA, Chan S, Kastner P, Canals JM, Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017 Apr 15;144(8):1566-1577 |
1 | J:327110 Mullen RD, Bellessort B, Levi G, Behringer RR, Distal-less homeobox genes Dlx5/6 regulate Mullerian duct regression. Front Endocrinol (Lausanne). 2022;13:916173 |
2 | J:136019 Nishida H, Miyagawa S, Vieux-Rochas M, Morini M, Ogino Y, Suzuki K, Nakagata N, Choi HS, Levi G, Yamada G, Positive regulation of steroidogenic acute regulatory protein gene expression through the interaction between Dlx and GATA-4 for testicular steroidogenesis. Endocrinology. 2008 May;149(5):2090-7 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:357469 Sivori M, Dempsey B, Chettouh Z, Boismoreau F, Ayerdi M, et al., The pelvic organs receive no parasympathetic innervation. Elife. 2024;15 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1* | J:245930 Sugii H, Grimaldi A, Li J, Parada C, Vu-Ho T, Feng J, Jing J, Yuan Y, Guo Y, Maeda H, Chai Y, The Dlx5-FGF10 signaling cascade controls cranial neural crest and myoblast interaction during oropharyngeal patterning and development. Development. 2017 Nov 01;144(21):4037-4045 |
1* | J:64588 Toresson H, Potter SS, Campbell K, Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for pax6 and gsh2. Development. 2000 Oct;127(20):4361-71 |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
1 | J:89175 Woodside KJ, Shen H, Muntzel C, Daller JA, Sommers CL, Love PE, Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes. Gene Expr Patterns. 2004 May;4(3):315-20 |
1* | J:87163 Zhang Z, Song Y, Zhang X, Tang J, Chen J, Chen Y, Msx1/Bmp4 genetic pathway regulates mammalian alveolar bone formation via induction of Dlx5 and Cbfa1. Mech Dev. 2003 Dec;120(12):1469-79 |
1* | J:62179 Zhao Z, Stock D, Buchanan A, Weiss K, Expression of Dlx genes during the development of the murine dentition. Dev Genes Evol. 2000 May;210(5):270-5 |
1* | J:157752 Zimmer C, Tiveron MC, Bodmer R, Cremer H, Dynamics of Cux2 expression suggests that an early pool of SVZ precursors is fated to become upper cortical layer neurons. Cereb Cortex. 2004 Dec;14(12):1408-20 |
Dlx6 distal-less homeobox 6 | |
Results | Reference |
1 | J:44591 Garel S, Marin F, Grosschedl R, Charnay P, Ebf1 controls early cell differentiation in the embryonic striatum. Development. 1999 Dec;126(23):5285-94 |
1 | J:82656 Hevner RF, Neogi T, Englund C, Daza RA, Fink A, Cajal-Retzius cells in the mouse: transcription factors, neurotransmitters, and birthdays suggest a pallial origin. Brain Res Dev Brain Res. 2003 Mar 14;141(1-2):39-53 |
1 | J:240536 Martin-Ibanez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Garcia-Diaz Barriga G, Edel MJ, Vicario-Abejon C, Alberch J, Girault JA, Chan S, Kastner P, Canals JM, Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017 Apr 15;144(8):1566-1577 |
1 | J:327110 Mullen RD, Bellessort B, Levi G, Behringer RR, Distal-less homeobox genes Dlx5/6 regulate Mullerian duct regression. Front Endocrinol (Lausanne). 2022;13:916173 |
2 | J:136019 Nishida H, Miyagawa S, Vieux-Rochas M, Morini M, Ogino Y, Suzuki K, Nakagata N, Choi HS, Levi G, Yamada G, Positive regulation of steroidogenic acute regulatory protein gene expression through the interaction between Dlx and GATA-4 for testicular steroidogenesis. Endocrinology. 2008 May;149(5):2090-7 |
1* | J:64588 Toresson H, Potter SS, Campbell K, Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for pax6 and gsh2. Development. 2000 Oct;127(20):4361-71 |
1 | J:89175 Woodside KJ, Shen H, Muntzel C, Daller JA, Sommers CL, Love PE, Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes. Gene Expr Patterns. 2004 May;4(3):315-20 |
1* | J:62179 Zhao Z, Stock D, Buchanan A, Weiss K, Expression of Dlx genes during the development of the murine dentition. Dev Genes Evol. 2000 May;210(5):270-5 |
Dlx6os1 distal-less homeobox 6, opposite strand 1 (Synonyms: A230055N17Rik, Dlx6as1, Dlx6os1, Evf-1, Evf1, Evf1/2, Evf-2, Evf2, mEvf-1, Shhrs) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Dmbt1 deleted in malignant brain tumors 1 (Synonyms: CRP-[a], CRP-[b], Crpd, ebnerin, gp300, hensin, MUCLIN, vomeroglandin) | |
Results | Reference |
2* | J:30445 De Lisle RC, Isom KS, Expression of sulfated gp300 and changes in glycosylation during pancreatic development. J Histochem Cytochem. 1996 Jan;44(1):57-66 |
Dmbx1 diencephalon/mesencephalon homeobox 1 (Synonyms: Atx, Cdmx, Dmbx1, Mbx, Otx3) | |
Results | Reference |
1* | J:76815 Broccoli V, Colombo E, Cossu G, Dmbx1 is a paired-box containing gene specifically expressed in the caudal most brain structures. Mech Dev. 2002 Jun;114(1-2):219 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:78146 Zhang Y, Miki T, Iwanaga T, Koseki Y, Okuno M, Sunaga Y, Ozaki N, Yano H, Koseki H, Seino S, Identification, tissue expression, and functional characterization of Otx3, a novel member of the Otx family. J Biol Chem. 2002 Aug 2;277(31):28065-9 |
Dmc1 DNA meiotic recombinase 1 (Synonyms: Dmc1, Dmc1h, Mei11, sgdp) | |
Results | Reference |
1 | J:211663 Fukuda T, Fukuda N, Agostinho A, Hernandez-Hernandez A, Kouznetsova A, Hoog C, STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. EMBO J. 2014 Jun 2;33(11):1243-55 |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
1* | J:86170 Menke DB, Koubova J, Page DC, Sexual differentiation of germ cells in XX mouse gonads occurs in an anterior-to-posterior wave. Dev Biol. 2003 Oct 15;262(2):303-12 |
1* | J:242348 Soh YQS, Mikedis MM, Kojima M, Godfrey AK, de Rooij DG, Page DC, Meioc maintains an extended meiotic prophase I in mice. PLoS Genet. 2017 Apr;13(4):e1006704 |
1 | J:281207 Vazquez BN, Blengini CS, Hernandez Y, Serrano L, Schindler K, SIRT7 promotes chromosome synapsis during prophase I of female meiosis. Chromosoma. 2019 Sep;128(3):369-383 |
1 | J:362758 Zhang L, Li Y, Hu Y, Chen M, Cen C, Chen M, Lin L, Zhou J, Wang M, Cui X, Tang F, Gao F, Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression. FASEB J. 2022 Feb;36(2):e22131 |
Dmd dystrophin, muscular dystrophy (Synonyms: Dp427, Dp71, Duchenne muscular dystrophy, dys, mdx, pke, X-linked muscular dystrophy) | |
Results | Reference |
1* | J:361965 Fujimoto T, Mori M, Tonosaki M, Yaoi T, Nakano K, Okamura T, Itoh K, Characterization of Dystrophin Dp71 Expression and Interaction Partners in Embryonic Brain Development: Implications for Duchenne/Becker Muscular Dystrophy. Mol Neurobiol. 2025 Jan 6; |
1 | J:334506 Gleneadie HJ, Fernandez-Ruiz B, Sardini A, Van de Pette M, Dimond A, Prinjha RK, McGinty J, French PMW, Bagci H, Merkenschlager M, Fisher AG, Endogenous bioluminescent reporters reveal a sustained increase in utrophin gene expression upon EZH2 and ERK1/2 inhibition. Commun Biol. 2023 Mar 25;6(1):318 |
Dmkn dermokine (Synonyms: 1110014F24Rik, cI-36, dermokine, Dmkn, sk30, sk89) | |
Results | Reference |
1* | J:119780 Bazzi H, Fantauzzo KA, Richardson GD, Jahoda CA, Christiano AM, Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression. Dev Dyn. 2007 Mar 1;236(4):961-970 |
1 | J:91454 Matsui T, Hayashi-Kisumi F, Kinoshita Y, Katahira S, Morita K, Miyachi Y, Ono Y, Imai T, Tanigawa Y, Komiya T, Tsukita S, Identification of novel keratinocyte-secreted peptides dermokine-alpha/-beta and a new stratified epithelium-secreted protein gene complex on human chromosome 19q13.1. Genomics. 2004 Aug;84(2):384-97 |
2 | J:91898 Moffatt P, Salois P, St-Amant N, Gaumond MH, Lanctot C, Identification of a conserved cluster of skin-specific genes encoding secreted proteins. Gene. 2004 Jun 9;334:123-31 |
Dmp1 dentin matrix protein 1 | |
Results | Reference |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
1* | J:111429 Feng JQ, Zhang J, Dallas SL, Lu Y, Chen S, Tan X, Owen M, Harris SE, MacDougall M, Dentin matrix protein 1, a target molecule for Cbfa1 in bone, is a unique bone marker gene. J Bone Miner Res. 2002 Oct;17(10):1822-31 |
3* | J:227060 Fujikawa K, Yokohama-Tamaki T, Morita T, Baba O, Qin C, Shibata S, An in situ hybridization study of perlecan, DMP1, and MEPE in developing condylar cartilage of the fetal mouse mandible and limb bud cartilage. Eur J Histochem. 2015;59(3):2553 |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1 | J:197592 Kyono A, Avishai N, Ouyang Z, Landreth GE, Murakami S, FGF and ERK signaling coordinately regulate mineralization-related genes and play essential roles in osteocyte differentiation. J Bone Miner Metab. 2012 Jan;30(1):19-30 |
1 | J:314657 Lin S, Zhang Q, Cao Z, Lu Y, Zhang H, Yan K, Liu Y, McKee MD, Qin C, Chen Z, Feng JQ, Constitutive nuclear expression of dentin matrix protein 1 fails to rescue the Dmp1-null phenotype. J Biol Chem. 2014 Aug 1;289(31):21533-43 |
1* | J:307192 Yadav PS, Feng S, Cong Q, Kim H, Liu Y, Yang Y, Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118 |
1 | J:329949 Yuan H, Xie B, Yu X, Lin C, Li M, Zhang Y, Zou X, Lu M, Zhao M, Wen X, A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development. Front Physiol. 2022;13:981311 |
2* | J:336094 Zheng H, Zhang X, Fu J, Xue Y, Chen Z, Yang G, Chen Y, Chen D, Yuan G, CHIP inhibits odontoblast differentiation through promoting DLX3 polyubiquitylation and degradation. Development. 2023 May 15;150(10):dev200848 |
Dmpk dystrophia myotonica-protein kinase (Synonyms: DM, Dm15) | |
Results | Reference |
1* | J:138797 Harmon EB, Harmon ML, Larsen TD, Paulson AF, Perryman MB, Myotonic dystrophy protein kinase is expressed in embryonic myocytes and is required for myotube formation. Dev Dyn. 2008 Sep;237(9):2353-66 |
1* | J:23408 Jansen G, Bartolomei M, Kalscheuer V, Merkx G, Wormskamp N, Mariman E, Smeets D, Ropers HH, Wieringa B, No imprinting involved in the expression of DM-kinase mRNAs in mouse and human tissues. Hum Mol Genet. 1993 Aug;2(8):1221-7 |
1* | J:85713 Kanadia RN, Urbinati CR, Crusselle VJ, Luo D, Lee YJ, Harrison JK, Oh SP, Swanson MS, Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3. Gene Expr Patterns. 2003 Aug;3(4):459-62 |
1* | J:43635 Laurent A, Pinset C, Aurade F, Vidaud M, Montarras D, Expression of myotonic dystrophy protein kinase gene during in vivo and in vitro mouse myogenesis. Cell Mol Biol (Noisy-Le-Grand). 1997 Sep;43(6):881-8 |
Dmrt1 doublesex and mab-3 related transcription factor 1 | |
Results | Reference |
1* | J:60422 De Grandi A, Calvari V, Bertini V, Bulfone A, Peverali G, Camerino G, Borsani G, Guioli S, The expression pattern of a mouse doublesex-related gene is consistent with a role in gonadal differentiation. Mech Dev. 2000 Feb;90(2):323-6 |
1* | J:297658 Kulibin AY, Malolina EA, Formation of the rete testis during mouse embryonic development. Dev Dyn. 2020 Aug 27; |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
Dmrt3 doublesex and mab-3 related transcription factor 3 | |
Results | Reference |
1* | J:321845 Bernhardt N, Memic F, Velica A, Tran MA, Vieillard J, Sayyab S, Chersa T, Andersson L, Whelan PJ, Boije H, Kullander K, Hop Mice Display Synchronous Hindlimb Locomotion and a Ventrally Fused Lumbar Spinal Cord Caused by a Point Mutation in Ttc26. eNeuro. 2022 Mar-Apr;9(2):ENEURO.0518-21.2022 |
2 | J:315293 Kumamoto T, Toma K, Gunadi, McKenna WL, Kasukawa T, Katzman S, Chen B, Hanashima C, Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013 Mar 28;3(3):931-45 |
1 | J:287023 Schnerwitzki D, Perry S, Ivanova A, Caixeta FV, Cramer P, Gunther S, Weber K, Tafreshiha A, Becker L, Vargas Panesso IL, Klopstock T, Hrabe de Angelis M, Schmidt M, Kullander K, Englert C, Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord. Life Sci Alliance. 2018 Aug;1(4):e201800106 |
Dmrta1 doublesex and mab-3 related transcription factor like family A1 (Synonyms: Dmrt4) | |
Results | Reference |
2 | J:315293 Kumamoto T, Toma K, Gunadi, McKenna WL, Kasukawa T, Katzman S, Chen B, Hanashima C, Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013 Mar 28;3(3):931-45 |
Dmrta2 doublesex and mab-3 related transcription factor like family A2 (Synonyms: Dmrt5) | |
Results | Reference |
1* | J:215770 Poulain M, Frydman N, Tourpin S, Mucsynski V, Souquet B, Benachi A, Habert R, Rouiller-Fabre V, Livera G, Involvement of doublesex and mab-3-related transcription factors in human female germ cell development demonstrated by xenograft and interference RNA strategies. Mol Hum Reprod. 2014 Oct;20(10):960-71 |
1 | J:287604 Ratie L, Desmaris E, Garcia-Moreno F, Hoerder-Suabedissen A, Kelman A, Theil T, Bellefroid EJ, Molnar Z, Loss of Dmrt5 Affects the Formation of the Subplate and Early Corticogenesis. Cereb Cortex. 2020 May 14;30(5):3296-3312 |
Dmrtc2 doublesex and mab-3 related transcription factor like family C2 (Synonyms: 4933432E21Rik, Dmrt7) | |
Results | Reference |
1* | J:82502 Kim S, Kettlewell JR, Anderson RC, Bardwell VJ, Zarkower D, Sexually dimorphic expression of multiple doublesex-related genes in the embryonic mouse gonad. Gene Expr Patterns. 2003 Mar;3(1):77-82 |
Dmwd dystrophia myotonica-containing WD repeat motif (Synonyms: 59, Dm9, DMR-N9) | |
Results | Reference |
1* | J:25210 Jansen G, Bachner D, Coerwinkel M, Wormskamp N, Hameister H, Wieringa B, Structural organization and developmental expression pattern of the mouse WD-repeat gene DMR-N9 immediately upstream of the myotonic dystrophy locus. Hum Mol Genet. 1995 May;4(5):843-52 |
Dmxl2 Dmx-like 2 (Synonyms: 6430411K14Rik, E130119P06Rik) | |
Results | Reference |
1 | J:271760 Gobe C, Elzaiat M, Meunier N, Andre M, Sellem E, Congar P, Jouneau L, Allais-Bonnet A, Naciri I, Passet B, Pailhoux E, Pannetier M, Dual role of DMXL2 in olfactory information transmission and the first wave of spermatogenesis. PLoS Genet. 2019 Feb;15(2):e1007909 |
Dnaaf1 dynein, axonemal assembly factor 1 (Synonyms: 4930457P18Rik, Lrrc50, m4Bei) | |
Results | Reference |
1* | J:158467 Loges NT, Olbrich H, Becker-Heck A, Haffner K, Heer A, Reinhard C, Schmidts M, Kispert A, Zariwala MA, Leigh MW, Knowles MR, Zentgraf H, Seithe H, Nurnberg G, Nurnberg P, Reinhardt R, Omran H, Deletions and point mutations of LRRC50 cause primary ciliary dyskinesia due to dynein arm defects. Am J Hum Genet. 2009 Dec;85(6):883-9 |
Dnah8 dynein, axonemal, heavy chain 8 (Synonyms: Dnahc8, Hst6.7b, P1-Loop) | |
Results | Reference |
1 | J:335572 Chen Z, Lei Y, Finnell RH, Ding Y, Su Z, Wang Y, Xie H, Chen F, Whole-exome sequencing study of hypospadias. iScience. 2023 May 19;26(5):106663 |
Dnah9 dynein, axonemal, heavy chain 9 (Synonyms: D11Ertd686e, Dnahc9) | |
Results | Reference |
1 | J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6 |
Dnah11 dynein, axonemal, heavy chain 11 (Synonyms: avc4, b2b1203Clo, b2b1279Clo, b2b1289Clo, b2b1727Clo, b2b598Clo, Dnahc11, lrd) | |
Results | Reference |
1 | J:44093 Supp DM, Witte DP, Potter SS, Brueckner M, Mutation of an axonemal dynein affects left-right asymmetry in inversus viscerum mice. Nature. 1997 Oct 30;389(6654):963-6 |
Dnai3 dynein axonemal intermediate chain 3 (Synonyms: 4931433A13Rik, IC140, Ida7, Wdr63) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 (Synonyms: Dnajc3, Dnajc3a, Dnajc3b, mp58, p58IPK, Prkri) | |
Results | Reference |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
Dnali1 dynein, axonemal, light intermediate polypeptide 1 (Synonyms: 1700023A09Rik) | |
Results | Reference |
1* | J:253968 Abdelhamed Z, Vuong SM, Hill L, Shula C, Timms A, Beier D, Campbell K, Mangano FT, Stottmann RW, Goto J, A mutation in Ccdc39 causes neonatal hydrocephalus with abnormal motile cilia development in mice. Development. 2018 Jan 9;145(1):dev154500 |
Dnd1 DND microRNA-mediated repression inhibitor 1 (Synonyms: MGC:41452, RBMS4, Ter) | |
Results | Reference |
1 | J:334114 Ruthig VA, Hatkevich T, Hardy J, Friedersdorf MB, Mayere C, Nef S, Keene JD, Capel B, The RNA binding protein DND1 is elevated in a subpopulation of pro-spermatogonia and targets chromatin modifiers and translational machinery during late gestation. PLoS Genet. 2023 Mar;19(3):e1010656 |
1 | J:334500 Ruthig VA, Yokonishi T, Friedersdorf MB, Batchvarova S, Hardy J, Garness JA, Keene JD, Capel B, A transgenic DND1GFP fusion allele reports in vivo expression and RNA-binding targets in undifferentiated mouse germ cells. Biol Reprod. 2021 Apr 1;104(4):861-874 |
1 | J:230058 Suzuki A, Niimi Y, Shinmyozu K, Zhou Z, Kiso M, Saga Y, Dead end1 is an essential partner of NANOS2 for selective binding of target RNAs in male germ cell development. EMBO Rep. 2016 Jan;17(1):37-46 |
Dner delta/notch-like EGF repeat containing (Synonyms: A930026D19Rik, BET, MGC:39059) | |
Results | Reference |
2* | J:319916 Du J, Wang X, Zhang X, Zhang X, Jiang H, DNER modulates the length, polarity and synaptogenesis of spiral ganglion neurons via the Notch signaling pathway. Mol Med Rep. 2018 Feb;17(2):2357-2365 |
Dnm1 dynamin 1 (Synonyms: dynamin 1, Ftfl) | |
Results | Reference |
1* | J:56117 Noakes PG, Chin D, Kim SS, Liang S, Phillips WD, Expression and localisation of dynamin and syntaxin during neural development and neuromuscular synapse formation. J Comp Neurol. 1999 Aug 9;410(4):531-40 |
Dnm1l dynamin 1-like (Synonyms: 6330417M19Rik, Dnmlp1, Drp1, python) | |
Results | Reference |
1 | J:224310 Ishihara T, Ban-Ishihara R, Maeda M, Matsunaga Y, Ichimura A, Kyogoku S, Aoki H, Katada S, Nakada K, Nomura M, Mizushima N, Mihara K, Ishihara N, Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development. Mol Cell Biol. 2015 Jan;35(1):211-23 |
1 | J:333326 Suh J, Kim NK, Shim W, Lee SH, Kim HJ, Moon E, Sesaki H, Jang JH, Kim JE, Lee YS, Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab. 2023 Feb 7;35(2):345-360.e7 |
Dnm2 dynamin 2 (Synonyms: b2b2159Clo, Dyn2) | |
Results | Reference |
1* | J:211544 Koutsopoulos OS, Kretz C, Weller CM, Roux A, Mojzisova H, Bohm J, Koch C, Toussaint A, Heckel E, Stemkens D, Ter Horst SA, Thibault C, Koch M, Mehdi SQ, Bijlsma EK, Mandel JL, Vermot J, Laporte J, Dynamin 2 homozygous mutation in humans with a lethal congenital syndrome. Eur J Hum Genet. 2013 Jun;21(6):637-42 |
Dnm3 dynamin 3 (Synonyms: 9630020E24Rik, B230343F03Rik, mKIAA0820) | |
Results | Reference |
1* | J:99344 Loebel DA, Tsoi B, Wong N, Tam PP, A conserved noncoding intronic transcript at the mouse Dnm3 locus. Genomics. 2005 Jun;85(6):782-9 |
Dnm3os dynamin 3, opposite strand (Synonyms: 6030416H16Rik, Hag2, Npn1, P/L01) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
1* | J:99344 Loebel DA, Tsoi B, Wong N, Tam PP, A conserved noncoding intronic transcript at the mouse Dnm3 locus. Genomics. 2005 Jun;85(6):782-9 |
Dnmbp dynamin binding protein (Synonyms: 2410003L07Rik, 2410003M15Rik, Tuba) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
Dnmt1 DNA methyltransferase 1 (Synonyms: Cxxc9, Dnmt1o, MommeD2, MTase) | |
Results | Reference |
1 | J:224084 Elliott EN, Sheaffer KL, Schug J, Stappenbeck TS, Kaestner KH, Dnmt1 is essential to maintain progenitors in the perinatal intestinal epithelium. Development. 2015 Jun 15;142(12):2163-72 |
1 | J:92186 La Salle S, Mertineit C, Taketo T, Moens PB, Bestor TH, Trasler JM, Windows for sex-specific methylation marked by DNA methyltransferase expression profiles in mouse germ cells. Dev Biol. 2004 Apr 15;268(2):403-15 |
1* | J:50138 Niederreither K, Harbers M, Chambon P, Dolle P, Expression of T:G mismatch-specific thymidine-DNA glycosylase and DNA methyl transferase genes during development and tumorigenesis. Oncogene. 1998 Sep 24;17(12):1577-85 |
2 | J:79935 Sakai Y, Suetake I, Itoh K, Mizugaki M, Tajima S, Yamashina S, Expression of DNA methyltransferase (Dnmt1) in testicular germ cells during development of mouse embryo. Cell Struct Funct. 2001 Dec;26(6):685-91 |
Dnmt3a DNA methyltransferase 3A | |
Results | Reference |
1 | J:155865 Aravin AA, van der Heijden GW, Castaneda J, Vagin VV, Hannon GJ, Bortvin A, Cytoplasmic compartmentalization of the fetal piRNA pathway in mice. PLoS Genet. 2009 Dec;5(12):e1000764 |
2* | J:133343 Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Totoki Y, Toyoda A, Ikawa M, Asada N, Kojima K, Yamaguchi Y, Ijiri TW, Hata K, Li E, Matsuda Y, Kimura T, Okabe M, Sakaki Y, Sasaki H, Nakano T, DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev. 2008 Apr 1;22(7):908-17 |
1 | J:180117 Nasonkin IO, Lazo K, Hambright D, Brooks M, Fariss R, Swaroop A, Distinct nuclear localization patterns of DNA methyltransferases in developing and mature mammalian retina. J Comp Neurol. 2011 Jul 1;519(10):1914-30 |
1* | J:48528 Okano M, Xie S, Li E, Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases [letter]. Nat Genet. 1998 Jul;19(3):219-20 |
1 | J:256852 Rinaldi L, Avgustinova A, Martin M, Datta D, Solanas G, Prats N, Benitah SA, Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-gamma. Elife. 2017 Apr 20;6:e21697 |
1 | J:294778 Sun H, Zhao X, Zhang C, Zhang Z, Lun J, Liao W, Zhang Z, MiR-455-3p inhibits the degenerate process of chondrogenic differentiation through modification of DNA methylation. Cell Death Dis. 2018 May 1;9(5):537 |
1* | J:79524 Watanabe D, Suetake I, Tada T, Tajima S, Stage- and cell-specific expression of Dnmt3a and Dnmt3b during embryogenesis. Mech Dev. 2002 Oct;118(1-2):187 |
Dnmt3b DNA methyltransferase 3B | |
Results | Reference |
1 | J:305337 Chen M, Wang Y, Lin L, Dong F, Wu H, Bao S, Gao F, PRMT7 is involved in regulation of germ cell proliferation during embryonic stage. Biochem Biophys Res Commun. 2020 Dec 17;533(4):938-944 |
1* | J:83990 Ishida C, Ura K, Hirao A, Sasaki H, Toyoda A, Sakaki Y, Niwa H, Li E, Kaneda Y, Genomic organization and promoter analysis of the Dnmt3b gene. Gene. 2003 May 22;310:151-9 |
1 | J:180117 Nasonkin IO, Lazo K, Hambright D, Brooks M, Fariss R, Swaroop A, Distinct nuclear localization patterns of DNA methyltransferases in developing and mature mammalian retina. J Comp Neurol. 2011 Jul 1;519(10):1914-30 |
1* | J:48528 Okano M, Xie S, Li E, Cloning and characterization of a family of novel mammalian DNA (cytosine-5) methyltransferases [letter]. Nat Genet. 1998 Jul;19(3):219-20 |
1* | J:79524 Watanabe D, Suetake I, Tada T, Tajima S, Stage- and cell-specific expression of Dnmt3a and Dnmt3b during embryogenesis. Mech Dev. 2002 Oct;118(1-2):187 |
1* | J:93502 Watanabe D, Suetake I, Tajima S, Hanaoka K, Expression of Dnmt3b in mouse hematopoietic progenitor cells and spermatogonia at specific stages. Gene Expr Patterns. 2004 Nov;5(1):43-9 |
Dnmt3l DNA methyltransferase 3-like (Synonyms: D6Ertd14e, ecat7) | |
Results | Reference |
1 | J:155865 Aravin AA, van der Heijden GW, Castaneda J, Vagin VV, Hannon GJ, Bortvin A, Cytoplasmic compartmentalization of the fetal piRNA pathway in mice. PLoS Genet. 2009 Dec;5(12):e1000764 |
1* | J:207604 Duffie R, Ajjan S, Greenberg MV, Zamudio N, Escamilla del Arenal M, Iranzo J, Okamoto I, Barbaux S, Fauque P, Bourc'his D, The Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals. Genes Dev. 2014 Mar 1;28(5):463-78 |
1 | J:252799 Itou D, Shiromoto Y, Yukiho SY, Ishii C, Nishimura T, Ogonuki N, Ogura A, Hasuwa H, Fujihara Y, Kuramochi-Miyagawa S, Nakano T, Induction of DNA methylation by artificial piRNA production in male germ cells. Curr Biol. 2015 Mar 30;25(7):901-6 |
1 | J:188056 Jameson SA, Lin YT, Capel B, Testis development requires the repression of Wnt4 by Fgf signaling. Dev Biol. 2012 Oct 1;370(1):24-32 |
2* | J:133343 Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Totoki Y, Toyoda A, Ikawa M, Asada N, Kojima K, Yamaguchi Y, Ijiri TW, Hata K, Li E, Matsuda Y, Kimura T, Okabe M, Sakaki Y, Sasaki H, Nakano T, DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev. 2008 Apr 1;22(7):908-17 |
1 | J:363950 Lee S, Kuramochi-Miyagawa S, Nagamori I, Nakano T, Effects of transgene insertion loci and copy number on Dnmt3L gene silencing through antisense transgene-derived PIWI-interacting RNAs. RNA. 2022;28(5):683-696 |
1* | J:209131 Saba R, Wu Q, Saga Y, CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways. Dev Biol. 2014 May 15;389(2):173-81 |
1 | J:362758 Zhang L, Li Y, Hu Y, Chen M, Cen C, Chen M, Lin L, Zhou J, Wang M, Cui X, Tang F, Gao F, Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression. FASEB J. 2022 Feb;36(2):e22131 |
Dnpep aspartyl aminopeptidase | |
Results | Reference |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
Dock1 dedicator of cytokinesis 1 (Synonyms: 9130006G06Rik, b2b3190Clo, D630004B07Rik, Dock180) | |
Results | Reference |
1* | J:302867 Laurin M, Dumouchel A, Fukui Y, Cote JF, The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo. Small GTPases. 2013 Oct-Dec;4(4):221-30 |
Dok5 docking protein 5 (Synonyms: 2700055C10Rik) | |
Results | Reference |
1 | J:201759 Pan Y, Zhang J, Liu W, Shu P, Yin B, Yuan J, Qiang B, Peng X, Dok5 is involved in the signaling pathway of neurotrophin-3 against TrkC-induced apoptosis. Neurosci Lett. 2013 Oct 11;553:46-51 |
Dok6 docking protein 6 (Synonyms: Dok-6) | |
Results | Reference |
1 | J:345844 Guo Y, Xiang P, Sun X, Liu W, Zhou J, Yin B, Hou L, Qiang B, Li H, Shu P, Peng X, Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy. Signal Transduct Target Ther. 2024 Feb 14;9(1):32 |
Donson downstream neighbor of SON (Synonyms: 1110025J21Rik, Donson, ORF60) | |
Results | Reference |
1 | J:304564 Venkataramanappa S, Schutz D, Saaber F, Kumar PA, Abe P, Schulz S, Stumm R, The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS Genet. 2021 Mar;17(3):e1009441 |
Dop1a DOP1 leucine zipper like protein A (Synonyms: B130005I07Rik, D9Ertd809e, Dopey1) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Dot1l DOT1 like histone lysine methyltransferase (Synonyms: KMT4, mDot1) | |
Results | Reference |
1 | J:332132 Cattaneo P, Hayes MGB, Baumgarten N, Hecker D, Peruzzo S, Aslan GS, Kunderfranco P, Larcher V, Zhang L, Contu R, Fonseca G, Spinozzi S, Chen J, Condorelli G, Dimmeler S, Schulz MH, Heinz S, Guimaraes-Camboa N, Evans SM, DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal. Nat Commun. 2022 Dec 2;13(1):7444 |
2 | J:269420 Franz H, Villarreal A, Heidrich S, Videm P, Kilpert F, Mestres I, Calegari F, Backofen R, Manke T, Vogel T, DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex. Nucleic Acids Res. 2019 Jan 10;47(1):168-183 |
1 | J:168140 Nguyen AT, Xiao B, Neppl RL, Kallin EM, Li J, Chen T, Wang DZ, Xiao X, Zhang Y, DOT1L regulates dystrophin expression and is critical for cardiac function. Genes Dev. 2011 Feb 1;25(3):263-74 |
Dpep3 dipeptidase 3 (Synonyms: 1700018F16Rik, MBD-3) | |
Results | Reference |
1* | J:243535 Yoshitake H, Yanagida M, Maruyama M, Takamori K, Hasegawa A, Araki Y, Molecular characterization and expression of dipeptidase 3, a testis-specific membrane-bound dipeptidase: complex formation with TEX101, a germ-cell-specific antigen in the mouse testis. J Reprod Immunol. 2011 Aug;90(2):202-13 |
Dpf1 double PHD fingers 1 (Synonyms: Neud4, neuro-d4) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
2 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
Dpf2 double PHD fingers 2 (Synonyms: 2210010M07Rik, Baf45d, Req, requiem, ubi-d4) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
Dpf3 double PHD fingers 3 (Synonyms: 2810403B03Rik, cer-d4, CERD4, Gm18872) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
1* | J:138780 Lange M, Kaynak B, Forster UB, Tonjes M, Fischer JJ, Grimm C, Schlesinger J, Just S, Dunkel I, Krueger T, Mebus S, Lehrach H, Lurz R, Gobom J, Rottbauer W, Abdelilah-Seyfried S, Sperling S, Regulation of muscle development by DPF3, a novel histone acetylation and methylation reader of the BAF chromatin remodeling complex. Genes Dev. 2008 Sep 1;22(17):2370-84 |
1 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
Dpp4 dipeptidylpeptidase 4 (Synonyms: Cd26, Dpp-4, THAM) | |
Results | Reference |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:342314 Jun S, Angueira AR, Fein EC, Tan JME, Weller AH, Cheng L, Batmanov K, Ishibashi J, Sakers AP, Stine RR, Seale P, Control of murine brown adipocyte development by GATA6. Dev Cell. 2023 Nov 6;58(21):2195-2205.e5 |
Dppa2 developmental pluripotency associated 2 (Synonyms: 2410088E07Rik, ECAT15-2) | |
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1* | J:116231 Maldonado-Saldivia J, van den Bergen J, Krouskos M, Gilchrist M, Lee C, Li R, Sinclair AH, Surani MA, Western PS, Dppa2 and Dppa4 Are Closely Linked SAP Motif Genes Restricted to Pluripotent Cells and the Germ Line. Stem Cells. 2007 Jan;25(1):19-28 |
Dppa3 developmental pluripotency-associated 3 (Synonyms: 2410075G02Rik, PGC7, stella) | |
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1* | J:76228 Sato M, Kimura T, Kurokawa K, Fujita Y, Abe K, Masuhara M, Yasunaga T, Ryo A, Yamamoto M, Nakano T, Identification of PGC7, a new gene expressed specifically in preimplantation embryos and germ cells. Mech Dev. 2002 Apr;113(1):91-4 |
Dppa4 developmental pluripotency associated 4 (Synonyms: 2410091M23Rik, ECAT15-1) | |
Results | Reference |
1* | J:116231 Maldonado-Saldivia J, van den Bergen J, Krouskos M, Gilchrist M, Lee C, Li R, Sinclair AH, Surani MA, Western PS, Dppa2 and Dppa4 Are Closely Linked SAP Motif Genes Restricted to Pluripotent Cells and the Germ Line. Stem Cells. 2007 Jan;25(1):19-28 |
Dppa5a developmental pluripotency associated 5A (Synonyms: Dppa5, ecat2, Esg1) | |
Results | Reference |
1* | J:115671 Tanaka TS, Lopez de Silanes I, Sharova LV, Akutsu H, Yoshikawa T, Amano H, Yamanaka S, Gorospe M, Ko MS, Esg1, expressed exclusively in preimplantation embryos, germline, and embryonic stem cells, is a putative RNA-binding protein with broad RNA targets. Dev Growth Differ. 2006 Aug;48(6):381-90 |
Dpt dermatopontin (Synonyms: 1810032B19Rik, 5033416F05Rik, early quiescence protein-1, EQ-1) | |
Results | Reference |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1 | J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522 |
Dpysl2 dihydropyrimidinase-like 2 (Synonyms: Crmp2, DRP2, TOAD-64, Ulip2) | |
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2* | J:47185 Kamata T, Subleski M, Hara Y, Yuhki N, Kung H, Copeland NG, Jenkins NA, Yoshimura T, Modi W, Copeland TD, Isolation and characterization of a bovine neural specific protein (CRMP-2) cDNA homologous to unc-33, a C. elegans gene implicated in axonal outgrowth and guidance. Brain Res Mol Brain Res. 1998 Mar 1;54(2):219-36 |
2 | J:293780 Yamazaki Y, Nagai J, Akinaga S, Koga Y, Hasegawa M, Takahashi M, Yamashita N, Kolattukudy P, Goshima Y, Ohshima T, Phosphorylation of CRMP2 is required for migration and positioning of Purkinje cells: Redundant roles of CRMP1 and CRMP4. Brain Res. 2020 Jun 1;1736:146762 |
Dpysl3 dihydropyrimidinase-like 3 (Synonyms: 9430041P20Rik, CRMP-4, CRMP4, TUC4, Ulip, Ulip1) | |
Results | Reference |
1* | J:226894 Niisato E, Nagai J, Yamashita N, Abe T, Kiyonari H, Goshima Y, Ohshima T, CRMP4 suppresses apical dendrite bifurcation of CA1 pyramidal neurons in the mouse hippocampus. Dev Neurobiol. 2012 Nov;72(11):1447-57 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
2 | J:293780 Yamazaki Y, Nagai J, Akinaga S, Koga Y, Hasegawa M, Takahashi M, Yamashita N, Kolattukudy P, Goshima Y, Ohshima T, Phosphorylation of CRMP2 is required for migration and positioning of Purkinje cells: Redundant roles of CRMP1 and CRMP4. Brain Res. 2020 Jun 1;1736:146762 |
Dpysl4 dihydropyrimidinase-like 4 (Synonyms: Crmp3, CRMP-3, DPY4, Drp-4, Ulip4, unc-33-like phosphoprotein 4) | |
Results | Reference |
1* | J:288330 Yasukawa M, Ishida K, Yuge Y, Hanaoka M, Minami Y, Ogawa M, Sasaki T, Saito M, Tsuji T, Dpysl4 is involved in tooth germ morphogenesis through growth regulation, polarization and differentiation of dental epithelial cells. Int J Biol Sci. 2013;9(4):382-90 |
Dpysl5 dihydropyrimidinase-like 5 (Synonyms: CRAM, Crmp5, CRMP-5) | |
Results | Reference |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Draxin dorsal inhibitory axon guidance protein (Synonyms: 2610109H07Rik, Neucrin) | |
Results | Reference |
1 | J:235552 Chinn GA, Hirokawa KE, Chuang TM, Urbina C, Patel F, Fong J, Funatsu N, Monuki ES, Agenesis of the Corpus Callosum Due to Defective Glial Wedge Formation in Lhx2 Mutant Mice. Cereb Cortex. 2015 Sep;25(9):2707-18 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Drc1 dynein regulatory complex subunit 1 (Synonyms: b2b1654Clo, Ccdc164, Gm1060, LOC381738) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Drc3 dynein regulatory complex subunit 3 (Synonyms: 4930449E07Rik, Lrrc48, m6Bei) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Drd1 dopamine receptor D1 (Synonyms: C030036C15Rik, D1 receptor, Drd-1, Drd1a, Gpcr15) | |
Results | Reference |
1 | J:361228 Li Z, Shang Z, Sun M, Jiang X, Tian Y, Yang L, Wang Z, Su Z, Liu G, Li X, You Y, Yang Z, Xu Z, Zhang Z, Transcription factor Sp9 is a negative regulator of D1-type MSN development. Cell Death Discov. 2022 Jun 30;8(1):301 |
1 | J:106280 Li ZS, Schmauss C, Cuenca A, Ratcliffe E, Gershon MD, Physiological modulation of intestinal motility by enteric dopaminergic neurons and the D2 receptor: analysis of dopamine receptor expression, location, development, and function in wild-type and knock-out mice. J Neurosci. 2006 Mar 8;26(10):2798-807 |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
1 | J:238868 Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z, The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 2016 Aug 02;16(5):1431-44 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
Drd2 dopamine receptor D2 (Synonyms: D2R, D2 receptor, Drd-2) | |
Results | Reference |
1* | J:32756 Fishburn CS, Bedford M, Lonai P, Fuchs S, Early expression of D3 dopamine receptors in murine embryonic development. FEBS Lett. 1996 Mar 4;381(3):257-61 |
1 | J:361228 Li Z, Shang Z, Sun M, Jiang X, Tian Y, Yang L, Wang Z, Su Z, Liu G, Li X, You Y, Yang Z, Xu Z, Zhang Z, Transcription factor Sp9 is a negative regulator of D1-type MSN development. Cell Death Discov. 2022 Jun 30;8(1):301 |
1 | J:106280 Li ZS, Schmauss C, Cuenca A, Ratcliffe E, Gershon MD, Physiological modulation of intestinal motility by enteric dopaminergic neurons and the D2 receptor: analysis of dopamine receptor expression, location, development, and function in wild-type and knock-out mice. J Neurosci. 2006 Mar 8;26(10):2798-807 |
1 | J:350099 Song X, Chen H, Shang Z, Du H, Li Z, Wen Y, Liu G, Qi D, You Y, Yang Z, Zhang Z, Xu Z, Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons. Neurosci Bull. 2021 Jul;37(7):985-998 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
3 | J:238868 Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z, The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 2016 Aug 02;16(5):1431-44 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
Drd3 dopamine receptor D3 (Synonyms: D3R, D3 receptor) | |
Results | Reference |
1* | J:32756 Fishburn CS, Bedford M, Lonai P, Fuchs S, Early expression of D3 dopamine receptors in murine embryonic development. FEBS Lett. 1996 Mar 4;381(3):257-61 |
1 | J:106280 Li ZS, Schmauss C, Cuenca A, Ratcliffe E, Gershon MD, Physiological modulation of intestinal motility by enteric dopaminergic neurons and the D2 receptor: analysis of dopamine receptor expression, location, development, and function in wild-type and knock-out mice. J Neurosci. 2006 Mar 8;26(10):2798-807 |
Drd4 dopamine receptor D4 (Synonyms: D4R, Drd-4) | |
Results | Reference |
1 | J:106280 Li ZS, Schmauss C, Cuenca A, Ratcliffe E, Gershon MD, Physiological modulation of intestinal motility by enteric dopaminergic neurons and the D2 receptor: analysis of dopamine receptor expression, location, development, and function in wild-type and knock-out mice. J Neurosci. 2006 Mar 8;26(10):2798-807 |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Drd5 dopamine receptor D5 (Synonyms: D5R, Drd1b, DRD1b, Drd-5, Gpcr1) | |
Results | Reference |
1 | J:106280 Li ZS, Schmauss C, Cuenca A, Ratcliffe E, Gershon MD, Physiological modulation of intestinal motility by enteric dopaminergic neurons and the D2 receptor: analysis of dopamine receptor expression, location, development, and function in wild-type and knock-out mice. J Neurosci. 2006 Mar 8;26(10):2798-807 |
1 | J:160518 Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, Jenkins RB, Tihan T, Vandenberg SR, James CD, Tanaka K, Taylor MD, Weiss WA, Chesler L, Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010 May 15;24(10):1059-72 |
Drgx dorsal root ganglia homeobox (Synonyms: Drg11, Prrxl1) | |
Results | Reference |
1* | J:84873 Ding YQ, Yin J, Xu HM, Jacquin MF, Chen ZF, Formation of whisker-related principal sensory nucleus-based lemniscal pathway requires a paired homeodomain transcription factor, Drg11. J Neurosci. 2003 Aug 13;23(19):7246-54 |
1 | J:76658 Gross MK, Dottori M, Goulding M, Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord. Neuron. 2002 May 16;34(4):535-49 |
1 | J:76655 Qian Y, Shirasawa S, Chen CL, Cheng L, Ma Q, Proper development of relay somatic sensory neurons and D2/D4 interneurons requires homeobox genes Rnx/Tlx-3 and Tlx-1. Genes Dev. 2002 May 15;16(10):1220-33 |
1* | J:160590 Rebelo S, Reguenga C, Lopes C, Lima D, Prrxl1 is required for the generation of a subset of nociceptive glutamatergic superficial spinal dorsal horn neurons. Dev Dyn. 2010 Jun;239(6):1684-94 |
1* | J:207190 Regadas I, Matos MR, Monteiro FA, Gomez-Skarmeta JL, Lima D, Bessa J, Casares F, Reguenga C, Several cis-regulatory elements control mRNA stability, translation efficiency, and expression pattern of Prrxl1 (paired related homeobox protein-like 1). J Biol Chem. 2013 Dec 20;288(51):36285-301 |
1 | J:212287 Soares-dos-Reis R, Pessoa AS, Matos MR, Falcao M, Mendes VM, Manadas B, Monteiro FA, Lima D, Reguenga C, Ser(1)(1)(9) phosphorylation modulates the activity and conformation of PRRXL1, a homeodomain transcription factor. Biochem J. 2014 May 1;459(3):441-53 |
1 | J:207050 Zhao X, Huang H, Chen Y, Liu Y, Zhang Z, Ma Q, Qiu M, Dynamic expression of secreted Frizzled-related protein 3 (sFRP3) in the developing mouse spinal cord and dorsal root ganglia. Neuroscience. 2013 Sep 17;248:594-601 |
Drosha drosha, ribonuclease type III (Synonyms: 1110013A17Rik, Etohi2, Rnasen) | |
Results | Reference |
1* | J:160269 Michon F, Tummers M, Kyyronen M, Frilander MJ, Thesleff I, Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol. 2010 Apr 15;340(2):355-68 |
Dsc1 desmocollin 1 (Synonyms: 1110020A10Rik, Dsc1a, Dsc1b) | |
Results | Reference |
1* | J:44442 King IA, Angst BD, Hunt DM, Kruger M, Arnemann J, Buxton RS, Hierarchical expression of desmosomal cadherins during stratified epithelial morphogenesis in the mouse. Differentiation. 1997 Nov;62(2):83-96 |
2 | J:35511 King IA, O'Brien TJ, Buxton RS, Expression of the skin-type desmosomal cadherin DSC1 is closely linked to the keratinization of epithelial tissues during mouse development. J Invest Dermatol. 1996 Oct;107(4):531-8 |
Dsc2 desmocollin 2 (Synonyms: Dsc2a, Dsc2b) | |
Results | Reference |
1* | J:44442 King IA, Angst BD, Hunt DM, Kruger M, Arnemann J, Buxton RS, Hierarchical expression of desmosomal cadherins during stratified epithelial morphogenesis in the mouse. Differentiation. 1997 Nov;62(2):83-96 |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Dsc3 desmocollin 3 (Synonyms: 5430426I24Rik) | |
Results | Reference |
1 | J:44061 Chidgey MA, Yue KK, Gould S, Byrne C, Garrod DR, Changing pattern of desmocollin 3 expression accompanies epidermal organisation during skin development. Dev Dyn. 1997 Nov;210(3):315-27 |
1 | J:105239 Den Z, Cheng X, Merched-Sauvage M, Koch PJ, Desmocollin 3 is required for pre-implantation development of the mouse embryo. J Cell Sci. 2006 Feb 1;119(Pt 3):482-9 |
1* | J:44442 King IA, Angst BD, Hunt DM, Kruger M, Arnemann J, Buxton RS, Hierarchical expression of desmosomal cadherins during stratified epithelial morphogenesis in the mouse. Differentiation. 1997 Nov;62(2):83-96 |
1 | J:202875 Tokonzaba E, Chen J, Cheng X, Den Z, Ganeshan R, Muller EJ, Koch PJ, Plakoglobin as a regulator of desmocollin gene expression. J Invest Dermatol. 2013 Dec;133(12):2732-40 |
Dscam DS cell adhesion molecule (Synonyms: 4932410A21Rik, Down syndrome cell adhesion molecule) | |
Results | Reference |
1 | J:313612 Arimura N, Okada M, Taya S, Dewa KI, Tsuzuki A, Uetake H, Miyashita S, Hashizume K, Shimaoka K, Egusa S, Nishioka T, Yanagawa Y, Yamakawa K, Inoue YU, Inoue T, Kaibuchi K, Hoshino M, DSCAM regulates delamination of neurons in the developing midbrain. Sci Adv. 2020 Sep;6(36) |
1 | J:297714 Brignani S, Raj DDA, Schmidt ERE, Dudukcu O, Adolfs Y, De Ruiter AA, Rybiczka-Tesulov M, Verhagen MG, van der Meer C, Broekhoven MH, Moreno-Bravo JA, Grossouw LM, Dumontier E, Cloutier JF, Chedotal A, Pasterkamp RJ, Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development. Neuron. 2020 Aug 19;107(4):684-702.e9 |
1 | J:240943 Bruce FM, Brown S, Smith JN, Fuerst PG, Erskine L, DSCAM promotes axon fasciculation and growth in the developing optic pathway. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1702-1707 |
1 | J:320476 Chen P, Liu Z, Zhang Q, Lin D, Song L, Liu J, Jiao HF, Lai X, Zou S, Wang S, Zhou T, Li BM, Zhu L, Pan BX, Fei E, DSCAM Deficiency Leads to Premature Spine Maturation and Autism-like Behaviors. J Neurosci. 2022 Jan 26;42(4):532-551 |
1 | J:192581 Maynard KR, Stein E, DSCAM contributes to dendrite arborization and spine formation in the developing cerebral cortex. J Neurosci. 2012 Nov 21;32(47):16637-50 |
1 | J:304361 Mitsogiannis MD, Pancho A, Aerts T, Sachse SM, Vanlaer R, Noterdaeme L, Schmucker D, Seuntjens E, Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration. Front Cell Dev Biol. 2020;8:624181 |
1* | J:45496 Yamakawat K, Huot YK, Haendelt MA, Hubert R, Chen XN, Lyons GE, Korenberg JR, DSCAM: a novel member of the immunoglobulin superfamily maps in a Down syndrome region and is involved in the development of the nervous system. Hum Mol Genet. 1998 Feb;7(2):227-37 |
Dscaml1 DS cell adhesion molecule like 1 (Synonyms: 4921507G06Rik, 4930435C18Rik, mKIAA1132) | |
Results | Reference |
2 | J:304361 Mitsogiannis MD, Pancho A, Aerts T, Sachse SM, Vanlaer R, Noterdaeme L, Schmucker D, Seuntjens E, Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration. Front Cell Dev Biol. 2020;8:624181 |
Dsg1a desmoglein 1 alpha (Synonyms: Dsg1) | |
Results | Reference |
1* | J:47740 Fausser JL, Schlepp O, Aberdam D, Meneguzzi G, Ruch JV, Lesot H, Localization of antigens associated with adherens junctions, desmosomes, and hemidesmosomes during murine molar morphogenesis. Differentiation. 1998 May;63(1):1-11 |
1* | J:44442 King IA, Angst BD, Hunt DM, Kruger M, Arnemann J, Buxton RS, Hierarchical expression of desmosomal cadherins during stratified epithelial morphogenesis in the mouse. Differentiation. 1997 Nov;62(2):83-96 |
1 | J:35511 King IA, O'Brien TJ, Buxton RS, Expression of the skin-type desmosomal cadherin DSC1 is closely linked to the keratinization of epithelial tissues during mouse development. J Invest Dermatol. 1996 Oct;107(4):531-8 |
Dsg2 desmoglein 2 (Synonyms: D18Ertd293e) | |
Results | Reference |
1* | J:47740 Fausser JL, Schlepp O, Aberdam D, Meneguzzi G, Ruch JV, Lesot H, Localization of antigens associated with adherens junctions, desmosomes, and hemidesmosomes during murine molar morphogenesis. Differentiation. 1998 May;63(1):1-11 |
1* | J:44442 King IA, Angst BD, Hunt DM, Kruger M, Arnemann J, Buxton RS, Hierarchical expression of desmosomal cadherins during stratified epithelial morphogenesis in the mouse. Differentiation. 1997 Nov;62(2):83-96 |
Dsg3 desmoglein 3 | |
Results | Reference |
1* | J:44442 King IA, Angst BD, Hunt DM, Kruger M, Arnemann J, Buxton RS, Hierarchical expression of desmosomal cadherins during stratified epithelial morphogenesis in the mouse. Differentiation. 1997 Nov;62(2):83-96 |
Dsp desmoplakin (Synonyms: 2300002E22Rik, 5730453H04Rik, DP, rul) | |
Results | Reference |
2 | J:104324 Hirschy A, Schatzmann F, Ehler E, Perriard JC, Establishment of cardiac cytoarchitecture in the developing mouse heart. Dev Biol. 2006 Jan 15;289(2):430-41 |
1 | J:182873 Jheon AH, Mostowfi P, Snead ML, Ihrie RA, Sone E, Pramparo T, Attardi LD, Klein OD, PERP regulates enamel formation via effects on cell-cell adhesion and gene expression. J Cell Sci. 2011 Mar 1;124(Pt 5):745-54 |
1* | J:325976 Piprek RP, Rams-Pociecha I, Zdanowski R, Kloc M, Kubiak JZ, Desmoplakin (Dsp) conditional knockout in NR5A1+ somatic cells affects germ cell survival in developing mouse gonads. Reproduction. 2022 Feb 24;163(4):199-207 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
1 | J:125580 Zhang L, Deng M, Kao CW, Kao WW, Xia Y, MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis. Mol Vis. 2003 Nov 3;9:584-93 |
Dspp dentin sialophosphoprotein (Synonyms: Dmp3, Dpp, Dsp) | |
Results | Reference |
1* | J:113417 Alvares K, Kanwar YS, Veis A, Expression and potential role of dentin phosphophoryn (DPP) in mouse embryonic tissues involved in epithelial-mesenchymal interactions and branching morphogenesis. Dev Dyn. 2006 Nov;235(11):2980-90 |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
1 | J:157869 Hamada Y, Sumiyoshi H, Matsuo N, Yun-Feng W, Nakashima M, Yanagisawa S, Yoshioka H, The pro-alpha2(XI) collagen gene is expressed in odontoblasts. Biochem Biophys Res Commun. 2010 Feb 5;392(2):166-70 |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
1* | J:237005 Verdelis K, Szabo-Rogers HL, Xu Y, Chong R, Kang R, Cusack BJ, Jani P, Boskey AL, Qin C, Beniash E, Accelerated enamel mineralization in Dspp mutant mice. Matrix Biol. 2016 May-Jul;52-54:246-59 |
1 | J:329949 Yuan H, Xie B, Yu X, Lin C, Li M, Zhang Y, Zou X, Lu M, Zhao M, Wen X, A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development. Front Physiol. 2022;13:981311 |
2* | J:336094 Zheng H, Zhang X, Fu J, Xue Y, Chen Z, Yang G, Chen Y, Chen D, Yuan G, CHIP inhibits odontoblast differentiation through promoting DLX3 polyubiquitylation and degradation. Development. 2023 May 15;150(10):dev200848 |
1 | J:316215 Zhou N, Li N, Liu J, Wang Y, Gao J, Wu Y, Chen X, Liu C, Xiao J, Persistent Wnt/beta-catenin signaling in mouse epithelium induces the ectopic Dspp expression in cheek mesenchyme. Organogenesis. 2019;15(1):1-12 |
Dst dystonin (Synonyms: 2310001O04Rik, A830042E19Rik, ah, athetoid, Bpag, Bpag1, BPAG1, BPAG1-n, bullous pemphigoid antigen 1, bullous pemphigoid antigen 1, Macf2, mKIAA0728, nmf203, nmf339) | |
Results | Reference |
1 | J:31811 Bernier G, Brown A, Dalpe G, De Repentigny Y, Mathieu M, Kothary R, Dystonin expression in the developing nervous system predominates in the neurons that degenerate in dystonia musculorum mutant mice. Mol Cell Neurosci. 1995 Dec;6(6):509-20 |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1* | J:47740 Fausser JL, Schlepp O, Aberdam D, Meneguzzi G, Ruch JV, Lesot H, Localization of antigens associated with adherens junctions, desmosomes, and hemidesmosomes during murine molar morphogenesis. Differentiation. 1998 May;63(1):1-11 |
1 | J:79981 Leonova EV, Lomax MI, Expression of the mouse Macf2 gene during inner ear development. Brain Res Mol Brain Res. 2002 Sep 30;105(1-2):67-78 |
Dstyk dual serine/threonine and tyrosine protein kinase (Synonyms: A930019K20Rik, C430014H23Rik) | |
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1* | J:118530 Peng J, Dong W, Chen Y, Mo R, Cheng JF, Hui CC, Mohandas N, Huang CH, Dusty protein kinases: primary structure, gene evolution, tissue specific expression and unique features of the catalytic domain. Biochim Biophys Acta. 2006 Nov-Dec;1759(11-12):562-72 |
Dtl denticleless E3 ubiquitin protein ligase (Synonyms: 2810047L02Rik, 5730564G15Rik) | |
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2 | J:352165 Lin Y, Tang W, Huang P, Wang Z, Duan L, Jia C, Sun R, Liu L, Shen J, Denticleless E3 ubiquitin protein ligase (DTL) maintains the proliferation and differentiation of epidermis and hair follicles during skin development. Dev Dyn. 2024 Jul;253(7):635-647 |
1* | J:118159 Liu CL, Yu IS, Pan HW, Lin SW, Hsu HC, L2dtl is essential for cell survival and nuclear division in early mouse embryonic development. J Biol Chem. 2007 Jan 12;282(2):1109-18 |
Dtna dystrobrevin alpha (Synonyms: 2210407P21Rik, 87K protein, A0, a-DB-1, adbn, alpha-dystrobrevin, Dtn) | |
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1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1 | J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12) |
Dtx1 deltex 1, E3 ubiquitin ligase (Synonyms: Fxit1) | |
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1* | J:73301 Mitsiadis TA, Gayet O, Zhang N, Carroll P, Expression of Deltex1 during mouse embryogenesis: comparison with Notch1, 2 and 3 expression. Mech Dev. 2001 Dec;109(2):399-403 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Dtx4 deltex 4, E3 ubiquitin ligase (Synonyms: RNF155) | |
Results | Reference |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Dubr Dppa2 upstream binding RNA (Synonyms: 5330426P16Rik, Dum) | |
Results | Reference |
1* | J:331896 Huang J, Jiang B, Li GW, Zheng D, Li M, Xie X, Pan Y, Wei M, Liu X, Jiang X, Zhang X, Yang L, Bao L, Wang B, m(6)A-modified lincRNA Dubr is required for neuronal development by stabilizing YTHDF1/3 and facilitating mRNA translation. Cell Rep. 2022 Nov 22;41(8):111693 |
Dusp1 dual specificity phosphatase 1 (Synonyms: 3CH134, erp, mkp-1, MKP1, Ptpn16) | |
Results | Reference |
1 | J:15758 Carrasco D, Bravo R, Expression of the nontransmembrane tyrosine phosphatase gene erp during mouse organogenesis. Cell Growth Differ. 1993 Oct;4(10):849-59 |
Dusp4 dual specificity phosphatase 4 (Synonyms: 2700078F24Rik, E130306H24Rik, MKP2) | |
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1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Dusp6 dual specificity phosphatase 6 (Synonyms: 1300019I03Rik, MKP-3, MKP3, PYST1) | |
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1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:163484 Lin MH, Chang KW, Lin SC, Miner JH, Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling. Dev Biol. 2010 Aug 15;344(2):707-19 |
1* | J:130480 Urness LD, Li C, Wang X, Mansour SL, Expression of ERK signaling inhibitors Dusp6, Dusp7, and Dusp9 during mouse ear development. Dev Dyn. 2008 Jan;237(1):163-9 |
Dusp9 dual specificity phosphatase 9 (Synonyms: Mpk4, Pyst3) | |
Results | Reference |
1* | J:130480 Urness LD, Li C, Wang X, Mansour SL, Expression of ERK signaling inhibitors Dusp6, Dusp7, and Dusp9 during mouse ear development. Dev Dyn. 2008 Jan;237(1):163-9 |
Dusp10 dual specificity phosphatase 10 (Synonyms: 2610306G15Rik, MKP-5, MKP5) | |
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1 | J:263373 Williams MA, Biguetti C, Romero-Bustillos M, Maheshwari K, Dinckan N, Cavalla F, Liu X, Silva R, Akyalcin S, Uyguner ZO, Vieira AR, Amendt BA, Fakhouri WD, Letra A, Colorectal Cancer-Associated Genes Are Associated with Tooth Agenesis and May Have a Role in Tooth Development. Sci Rep. 2018 Feb 14;8(1):2979 |
Dusp14 dual specificity phosphatase 14 (Synonyms: 1110014C10Rik, 2310042C07Rik, D11Ertd395e, Mkp6, MKP-L) | |
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2* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Duxbl1 double homeobox B-like 1 (Synonyms: 1110051B16Rik, Duxbl, Duxl) | |
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1 | J:156944 Wu SL, Tsai MS, Wong SH, Hsieh-Li HM, Tsai TS, Chang WT, Huang SL, Chiu CC, Wang SH, Characterization of genomic structures and expression profiles of three tandem repeats of a mouse double homeobox gene: Duxbl. Dev Dyn. 2010 Jan 8;239(3):927-940 |
Duxbl2 double homeobox B-like 2 (Synonyms: Gm10394) | |
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1 | J:156944 Wu SL, Tsai MS, Wong SH, Hsieh-Li HM, Tsai TS, Chang WT, Huang SL, Chiu CC, Wang SH, Characterization of genomic structures and expression profiles of three tandem repeats of a mouse double homeobox gene: Duxbl. Dev Dyn. 2010 Jan 8;239(3):927-940 |
Duxbl3 double homeobox B-like 3 (Synonyms: Gm10391) | |
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1 | J:156944 Wu SL, Tsai MS, Wong SH, Hsieh-Li HM, Tsai TS, Chang WT, Huang SL, Chiu CC, Wang SH, Characterization of genomic structures and expression profiles of three tandem repeats of a mouse double homeobox gene: Duxbl. Dev Dyn. 2010 Jan 8;239(3):927-940 |
Dvl1 dishevelled segment polarity protein 1 | |
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1 | J:21483 Sussman DJ, Klingensmith J, Salinas P, Adams PS, Nusse R, Perrimon N, Isolation and characterization of a mouse homolog of the Drosophila segment polarity gene dishevelled. Dev Biol. 1994 Nov;166(1):73-86 |
Dvl2 dishevelled segment polarity protein 2 | |
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1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:167714 Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, Chen H, Haneline LS, Chan RJ, Schwartz RJ, Field LJ, Atkinson SJ, Shou W, Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development. 2011 Jan;138(2):303-15 |
1 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
1* | J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20 |
Dync1h1 dynein cytoplasmic 1 heavy chain 1 (Synonyms: 9930018I23Rik, Dnchc1, Dnec1, dynein heavy chain, retrograde transport, Loa, MAP1C, mKIAA0325, Swl) | |
Results | Reference |
1 | J:334512 He S, Gillies JP, Zang JL, Cordoba-Beldad CM, Yamamoto I, Fujiwara Y, Grantham J, DeSantis ME, Shibuya H, Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity. Nat Commun. 2023 Mar 27;14(1):1715 |
1 | J:108133 Sekita Y, Wagatsuma H, Irie M, Kobayashi S, Kohda T, Matsuda J, Yokoyama M, Ogura A, Schuster-Gossler K, Gossler A, Ishino F, Kaneko-Ishino T, Aberrant regulation of imprinted gene expression in Gtl2lacZ mice. Cytogenet Genome Res. 2006;113(1-4):223-9 |
2* | J:105770 Tierling S, Dalbert S, Schoppenhorst S, Tsai CE, Oliger S, Ferguson-Smith AC, Paulsen M, Walter J, High-resolution map and imprinting analysis of the Gtl2-Dnchc1 domain on mouse chromosome 12. Genomics. 2006 Feb;87(2):225-35 |
Dync1i2 dynein cytoplasmic 1 intermediate chain 2 (Synonyms: 3110079H08Rik, Dncic2) | |
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1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Dynll1 dynein light chain LC8-type 1 (Synonyms: 8kDa LC, DLC8, Dnclc1, Pin) | |
Results | Reference |
1 | J:334512 He S, Gillies JP, Zang JL, Cordoba-Beldad CM, Yamamoto I, Fujiwara Y, Grantham J, DeSantis ME, Shibuya H, Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity. Nat Commun. 2023 Mar 27;14(1):1715 |
1* | J:186112 Jurado S, Conlan LA, Baker EK, Ng JL, Tenis N, Hoch NC, Gleeson K, Smeets M, Izon D, Heierhorst J, ATM substrate Chk2-interacting Zn2+ finger (ASCIZ) Is a bi-functional transcriptional activator and feedback sensor in the regulation of dynein light chain (DYNLL1) expression. J Biol Chem. 2012 Jan 27;287(5):3156-64 |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Dynll2 dynein light chain LC8-type 2 (Synonyms: 1700064A15Rik, 6720463E02Rik) | |
Results | Reference |
1 | J:334512 He S, Gillies JP, Zang JL, Cordoba-Beldad CM, Yamamoto I, Fujiwara Y, Grantham J, DeSantis ME, Shibuya H, Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity. Nat Commun. 2023 Mar 27;14(1):1715 |
Dynlrb1 dynein light chain roadblock-type 1 (Synonyms: 2010012N15Rik, 2010320M17Rik, Dncl2a, DNLC2A, km23-1) | |
Results | Reference |
1 | J:334512 He S, Gillies JP, Zang JL, Cordoba-Beldad CM, Yamamoto I, Fujiwara Y, Grantham J, DeSantis ME, Shibuya H, Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity. Nat Commun. 2023 Mar 27;14(1):1715 |
Dynlrb2 dynein light chain roadblock-type 2 (Synonyms: 1700009A04Rik, Dncl2b, DNLC2B) | |
Results | Reference |
1 | J:334512 He S, Gillies JP, Zang JL, Cordoba-Beldad CM, Yamamoto I, Fujiwara Y, Grantham J, DeSantis ME, Shibuya H, Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity. Nat Commun. 2023 Mar 27;14(1):1715 |
Dynlt1b dynein light chain Tctex-type 1B (Synonyms: Dynlt1, Tctex-1, Tctex1) | |
Results | Reference |
1* | J:161097 Gauthier-Fisher A, Lin DC, Greeve M, Kaplan DR, Rottapel R, Miller FD, Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells. Nat Neurosci. 2009 Jun;12(6):735-44 |
Dynlt1c dynein light chain Tctex-type 1C (Synonyms: Dynlt1d) | |
Results | Reference |
1 | J:334512 He S, Gillies JP, Zang JL, Cordoba-Beldad CM, Yamamoto I, Fujiwara Y, Grantham J, DeSantis ME, Shibuya H, Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity. Nat Commun. 2023 Mar 27;14(1):1715 |
Dynlt3 dynein light chain Tctex-type 3 (Synonyms: 2310075M16Rik, Tcte1l) | |
Results | Reference |
1 | J:334512 He S, Gillies JP, Zang JL, Cordoba-Beldad CM, Yamamoto I, Fujiwara Y, Grantham J, DeSantis ME, Shibuya H, Distinct dynein complexes defined by DYNLRB1 and DYNLRB2 regulate mitotic and male meiotic spindle bipolarity. Nat Commun. 2023 Mar 27;14(1):1715 |
Dyrk1a dual-specificity tyrosine phosphorylation regulated kinase 1a (Synonyms: 2310043O08Rik, D16Ertd272e, D16Ertd493e, Dyrk, Mnbh) | |
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2 | J:133208 Hammerle B, Elizalde C, Tejedor FJ, The spatio-temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrk1A in the developing mouse brain suggests distinct sequential roles in neuronal development. Eur J Neurosci. 2008 Mar;27(5):1061-74 |
Dyrk2 dual-specificity tyrosine phosphorylation regulated kinase 2 (Synonyms: 1810038L18Rik) | |
Results | Reference |
1 | J:312414 Yogosawa S, Ohkido M, Horii T, Okazaki Y, Nakayama J, Yoshida S, Toyokuni S, Hatada I, Morimoto M, Yoshida K, Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient. Commun Biol. 2021 Oct 20;4(1):1204 |
E2f1 E2F transcription factor 1 (Synonyms: E2F-1) | |
Results | Reference |
1* | J:88220 Amasaki H, Ogawa M, Nagasao J, Mutoh K, Ichihara N, Asari M, Shiota K, Distributional changes of BrdU, PCNA, E2F1 and PAL31 molecules in developing murine palatal rugae. Ann Anat. 2003 Dec;185(6):517-23 |
1* | J:108720 Berthet C, Klarmann KD, Hilton MB, Suh HC, Keller JR, Kiyokawa H, Kaldis P, Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation. Dev Cell. 2006 May;10(5):563-73 |
1* | J:42771 Dagnino L, Fry CJ, Bartley SM, Farnham P, Gallie BL, Phillips RA, Expression patterns of the E2F family of transcription factors during mouse nervous system development. Mech Dev. 1997 Aug;66(1-2):13-25 |
1 | J:89720 Fajas L, Annicotte JS, Miard S, Sarruf D, Watanabe M, Auwerx J, Impaired pancreatic growth, beta cell mass, and beta cell function in E2F1 (-/- )mice. J Clin Invest. 2004 May;113(9):1288-95 |
1* | J:63376 Kusek JC, Greene RM, Nugent P, Pisano MM, Expression of the E2F family of transcription factors during murine development. Int J Dev Biol. 2000 Apr;44(3):267-77 |
2* | J:31363 Tevosian SG, Paulson KE, Bronson R, Yee AS, Expression of the E2F-1/DP-1 transcription factor in murine development. Cell Growth Differ. 1996 Jan;7(1):43-52 |
1 | J:159853 Zhang J, Li H, Yabut O, Fitzpatrick H, D'Arcangelo G, Herrup K, Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex. J Neurosci. 2010 Apr 14;30(15):5219-28 |
1* | J:26610 Zhao J, Nornes HO, Neuman T, Expression of Rb, E2F1, cdc2, and D, and B cyclins in developing spinal cord. Neurosci Lett. 1995 Apr 28;190(1):49-52 |
E2f2 E2F transcription factor 2 | |
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1* | J:40858 Dagnino L, Fry CJ, Bartley SM, Farnham P, Gallie BL, Phillips RA, Expression patterns of the E2F family of transcription factors during murine epithelial development. Cell Growth Differ. 1997 May;8(5):553-63 |
1* | J:63376 Kusek JC, Greene RM, Nugent P, Pisano MM, Expression of the E2F family of transcription factors during murine development. Int J Dev Biol. 2000 Apr;44(3):267-77 |
1* | J:359452 Pang Y, Ruan X, Liu W, Hou L, Yin B, Shu P, Peng X, MicroRNA-495 Modulates Neuronal Layer Fate Determination by Targeting Tcf4. Int J Biol Sci. 2024;20(15):6207-6221 |
1 | J:159853 Zhang J, Li H, Yabut O, Fitzpatrick H, D'Arcangelo G, Herrup K, Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex. J Neurosci. 2010 Apr 14;30(15):5219-28 |
E2f3 E2F transcription factor 3 (Synonyms: E2f3a, E2F3b, mKIAA0075) | |
Results | Reference |
1* | J:63376 Kusek JC, Greene RM, Nugent P, Pisano MM, Expression of the E2F family of transcription factors during murine development. Int J Dev Biol. 2000 Apr;44(3):267-77 |
1 | J:159853 Zhang J, Li H, Yabut O, Fitzpatrick H, D'Arcangelo G, Herrup K, Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex. J Neurosci. 2010 Apr 14;30(15):5219-28 |
E2f4 E2F transcription factor 4 (Synonyms: 2010111M04Rik) | |
Results | Reference |
1* | J:63376 Kusek JC, Greene RM, Nugent P, Pisano MM, Expression of the E2F family of transcription factors during murine development. Int J Dev Biol. 2000 Apr;44(3):267-77 |
2* | J:176112 van Amerongen MJ, Diehl F, Novoyatleva T, Patra C, Engel FB, E2F4 is required for cardiomyocyte proliferation. Cardiovasc Res. 2010 Apr 1;86(1):92-102 |
1 | J:159853 Zhang J, Li H, Yabut O, Fitzpatrick H, D'Arcangelo G, Herrup K, Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex. J Neurosci. 2010 Apr 14;30(15):5219-28 |
E2f5 E2F transcription factor 5 (Synonyms: E2F-5) | |
Results | Reference |
1* | J:40858 Dagnino L, Fry CJ, Bartley SM, Farnham P, Gallie BL, Phillips RA, Expression patterns of the E2F family of transcription factors during murine epithelial development. Cell Growth Differ. 1997 May;8(5):553-63 |
1* | J:63376 Kusek JC, Greene RM, Nugent P, Pisano MM, Expression of the E2F family of transcription factors during murine development. Int J Dev Biol. 2000 Apr;44(3):267-77 |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
2* | J:105760 Swetloff A, Ferretti P, Changes in E2F5 intracellular localization in mouse and human choroid plexus epithelium with development. Int J Dev Biol. 2005;49(7):859-65 |
1 | J:159853 Zhang J, Li H, Yabut O, Fitzpatrick H, D'Arcangelo G, Herrup K, Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex. J Neurosci. 2010 Apr 14;30(15):5219-28 |
E2f6 E2F transcription factor 6 (Synonyms: EMA) | |
Results | Reference |
1* | J:63376 Kusek JC, Greene RM, Nugent P, Pisano MM, Expression of the E2F family of transcription factors during murine development. Int J Dev Biol. 2000 Apr;44(3):267-77 |
E2f7 E2F transcription factor 7 (Synonyms: A630014C11Rik, D10Ertd739e, E2F7) | |
Results | Reference |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
1 | J:159853 Zhang J, Li H, Yabut O, Fitzpatrick H, D'Arcangelo G, Herrup K, Cdk5 suppresses the neuronal cell cycle by disrupting the E2F1-DP1 complex. J Neurosci. 2010 Apr 14;30(15):5219-28 |
E230032D23Rik RIKEN cDNA E230032D23 gene | |
Results | Reference |
1* | J:186763 Esperon Ede L, Cordier G, Engel N, A genomic reservoir for Tnfrsf genes is developmentally regulated and imprinted in the mouse. Epigenetics. 2012 Jun 1;7(6):626-34 |
Ebf1 early B cell factor 1 (Synonyms: O/E-1, Olf-1, Olf1) | |
Results | Reference |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:76658 Gross MK, Dottori M, Goulding M, Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord. Neuron. 2002 May 16;34(4):535-49 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:164295 Jin K, Jiang H, Mo Z, Xiang M, Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors. J Neurosci. 2010 Sep 8;30(36):11902-16 |
2 | J:354051 Kagoshima H, Ohnishi H, Yamamoto R, Yasumoto A, Tona Y, Nakagawa T, Omori K, Yamamoto N, EBF1 Limits the Numbers of Cochlear Hair and Supporting Cells and Forms the Scala Tympani and Spiral Limbus during Inner Ear Development. J Neurosci. 2024 Feb 14;44(7) |
1 | J:361228 Li Z, Shang Z, Sun M, Jiang X, Tian Y, Yang L, Wang Z, Su Z, Liu G, Li X, You Y, Yang Z, Xu Z, Zhang Z, Transcription factor Sp9 is a negative regulator of D1-type MSN development. Cell Death Discov. 2022 Jun 30;8(1):301 |
1 | J:240536 Martin-Ibanez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Garcia-Diaz Barriga G, Edel MJ, Vicario-Abejon C, Alberch J, Girault JA, Chan S, Kastner P, Canals JM, Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017 Apr 15;144(8):1566-1577 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:226687 Morello F, Prasad AA, Rehberg K, Vieira de Sa R, Anton-Bolanos N, Leyva-Diaz E, Adolfs Y, Tissir F, Lopez-Bendito G, Pasterkamp RJ, Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development. J Neurosci. 2015 Oct 21;35(42):14205-19 |
1 | J:78037 Muzio L, DiBenedetto B, Stoykova A, Boncinelli E, Gruss P, Mallamaci A, Conversion of cerebral cortex into basal ganglia in Emx2(-/-) Pax6(Sey/Sey) double-mutant mice. Nat Neurosci. 2002 Aug;5(8):737-45 |
1 | J:328873 Shang Z, Yang L, Wang Z, Tian Y, Gao Y, Su Z, Guo R, Li W, Liu G, Li X, Yang Z, Li Z, Zhang Z, The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity. Front Cell Dev Biol. 2022;10:948331 |
1 | J:350099 Song X, Chen H, Shang Z, Du H, Li Z, Wen Y, Liu G, Qi D, You Y, Yang Z, Zhang Z, Xu Z, Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons. Neurosci Bull. 2021 Jul;37(7):985-998 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
1 | J:78453 Wang SS, Betz AG, Reed RR, Cloning of a Novel Olf-1/EBF-like Gene, O/E-4, by Degenerate Oligo-based Direct Selection. Mol Cell Neurosci. 2002 Jul;20(3):404-14 |
1 | J:264125 Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z, SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. Development. 2018 Jul 23;145(14):dev165456 |
2 | J:195329 Zee T, Boller S, Gyory I, Makinistoglu MP, Tuckermann JP, Grosschedl R, Karsenty G, The transcription factor early B-cell factor 1 regulates bone formation in an osteoblast-nonautonomous manner. FEBS Lett. 2013 Mar 18;587(6):711-6 |
1 | J:238868 Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z, The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 2016 Aug 02;16(5):1431-44 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
Ebf2 early B cell factor 2 (Synonyms: D14Ggc1e, Mmot1, O/E-3) | |
Results | Reference |
1* | J:314181 Holzman MA, Ryckman A, Finkelstein TM, Landry-Truchon K, Schindler KA, Bergmann JM, Jeannotte L, Mansfield JH, HOXA5 Participates in Brown Adipose Tissue and Epaxial Skeletal Muscle Patterning and in Brown Adipocyte Differentiation. Front Cell Dev Biol. 2021;9:632303 |
1 | J:164295 Jin K, Jiang H, Mo Z, Xiang M, Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors. J Neurosci. 2010 Sep 8;30(36):11902-16 |
1 | J:104946 Kieslinger M, Folberth S, Dobreva G, Dorn T, Croci L, Erben R, Consalez GG, Grosschedl R, EBF2 regulates osteoblast-dependent differentiation of osteoclasts. Dev Cell. 2005 Dec;9(6):757-67 |
1 | J:165655 Kieslinger M, Hiechinger S, Dobreva G, Consalez GG, Grosschedl R, Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner. Cell Stem Cell. 2010 Oct 8;7(4):496-507 |
2 | J:315293 Kumamoto T, Toma K, Gunadi, McKenna WL, Kasukawa T, Katzman S, Chen B, Hanashima C, Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013 Mar 28;3(3):931-45 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1 | J:78453 Wang SS, Betz AG, Reed RR, Cloning of a Novel Olf-1/EBF-like Gene, O/E-4, by Degenerate Oligo-based Direct Selection. Mol Cell Neurosci. 2002 Jul;20(3):404-14 |
1 | J:242450 Yang Q, Liu S, Yin M, Yin Y, Zhou G, Zhou J, Ebf2 is required for development of dopamine neurons in the midbrain periaqueductal gray matter of mouse. Dev Neurobiol. 2015 Nov;75(11):1282-94 |
Ebf3 early B cell factor 3 (Synonyms: 3110018A08Rik, O/E-2, Olf-1/EBF-like 2) | |
Results | Reference |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:164295 Jin K, Jiang H, Mo Z, Xiang M, Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors. J Neurosci. 2010 Sep 8;30(36):11902-16 |
2* | J:309086 Jin S, Kim J, Willert T, Klein-Rodewald T, Garcia-Dominguez M, Mosqueira M, Fink R, Esposito I, Hofbauer LC, Charnay P, Kieslinger M, Ebf factors and MyoD cooperate to regulate muscle relaxation via Atp2a1. Nat Commun. 2014 May 2;5:3793 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:357469 Sivori M, Dempsey B, Chettouh Z, Boismoreau F, Ayerdi M, et al., The pelvic organs receive no parasympathetic innervation. Elife. 2024;15 |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
1 | J:78453 Wang SS, Betz AG, Reed RR, Cloning of a Novel Olf-1/EBF-like Gene, O/E-4, by Degenerate Oligo-based Direct Selection. Mol Cell Neurosci. 2002 Jul;20(3):404-14 |
Ebf4 early B cell factor 4 (Synonyms: O/E-4, Olf-1/EBF-like 4) | |
Results | Reference |
1 | J:164295 Jin K, Jiang H, Mo Z, Xiang M, Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors. J Neurosci. 2010 Sep 8;30(36):11902-16 |
1 | J:78453 Wang SS, Betz AG, Reed RR, Cloning of a Novel Olf-1/EBF-like Gene, O/E-4, by Degenerate Oligo-based Direct Selection. Mol Cell Neurosci. 2002 Jul;20(3):404-14 |
Ecm1 extracellular matrix protein 1 (Synonyms: p85) | |
Results | Reference |
2* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Ecm2 extracellular matrix protein 2, female organ and adipocyte specific (Synonyms: 9030618O22Rik, tenonectin) | |
Results | Reference |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Ect2 ect2 oncogene | |
Results | Reference |
1 | J:290729 Grundl M, Walz S, Hauf L, Schwab M, Werner KM, Spahr S, Schulte C, Maric HM, Ade CP, Gaubatz S, Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes. PLoS Genet. 2020 May;16(5):e1008818 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Eda ectodysplasin-A (Synonyms: Ed1, EDA1, Eda-A1, Eda-A2) | |
Results | Reference |
1 | J:111051 Cui CY, Hashimoto T, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9142-7 |
1 | J:217500 Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D, Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:105968 Jaskoll T, Zhou YM, Trump G, Melnick M, Ectodysplasin receptor-mediated signaling is essential for embryonic submandibular salivary gland development. Anat Rec A Discov Mol Cell Evol Biol. 2003 Apr;271(2):322-31 |
1 | J:147576 Kunisada M, Cui CY, Piao Y, Ko MS, Schlessinger D, Requirement for Shh and Fox family genes at different stages in sweat gland development. Hum Mol Genet. 2009 May 15;18(10):1769-78 |
1* | J:278247 Kuony A, Ikkala K, Kalha S, Magalhaes AC, Pirttiniemi A, Michon F, Ectodysplasin-A signaling is a key integrator in the lacrimal gland-cornea feedback loop. Development. 2019 Jul 16;146(14):dev176693 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
Edar ectodysplasin-A receptor | |
Results | Reference |
1 | J:267642 Biggs LC, Makela OJ, Myllymaki SM, Das Roy R, Narhi K, Pispa J, Mustonen T, Mikkola ML, Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation. Elife. 2018 Jul 31;7:e36468 |
2 | J:217500 Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D, Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:334122 Glover JD, Sudderick ZR, Shih BB, Batho-Samblas C, Charlton L, Krause AL, Anderson C, Riddell J, Balic A, Li J, Klika V, Woolley TE, Gaffney EA, Corsinotti A, Anderson RA, Johnston LJ, Brown SJ, Wang S, Chen Y, Crichton ML, Headon DJ, The developmental basis of fingerprint pattern formation and variation. Cell. 2023 Mar 2;186(5):940-956.e20 |
1 | J:105968 Jaskoll T, Zhou YM, Trump G, Melnick M, Ectodysplasin receptor-mediated signaling is essential for embryonic submandibular salivary gland development. Anat Rec A Discov Mol Cell Evol Biol. 2003 Apr;271(2):322-31 |
1* | J:187370 Keil KP, Mehta V, Abler LL, Joshi PS, Schmitz CT, Vezina CM, Visualization and quantification of mouse prostate development by in situ hybridization. Differentiation. 2012 Oct;84(3):232-9 |
1 | J:147576 Kunisada M, Cui CY, Piao Y, Ko MS, Schlessinger D, Requirement for Shh and Fox family genes at different stages in sweat gland development. Hum Mol Genet. 2009 May 15;18(10):1769-78 |
1* | J:278247 Kuony A, Ikkala K, Kalha S, Magalhaes AC, Pirttiniemi A, Michon F, Ectodysplasin-A signaling is a key integrator in the lacrimal gland-cornea feedback loop. Development. 2019 Jul 16;146(14):dev176693 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1* | J:222345 Rogers SW, Gahring LC, Nicotinic receptor Alpha7 expression during tooth morphogenesis reveals functional pleiotropy. PLoS One. 2012;7(5):e36467 |
1 | J:215784 Sennett R, Rezza A, Dauber KL, Clavel C, Rendl M, Cxcr4 is transiently expressed in both epithelial and mesenchymal compartments of nascent hair follicles but is not required for follicle formation. Exp Dermatol. 2014 Oct;23(10):748-50 |
1 | J:359522 Villeneuve C, Hashmi A, Ylivinkka I, Lawson-Keister E, Miroshnikova YA, Perez-Gonzalez C, Myllymaki SM, Bertillot F, Yadav B, Zhang T, Matic Vignjevic D, Mikkola ML, Manning ML, Wickstrom SA, Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture. Nat Cell Biol. 2024 Feb;26(2):207-218 |
Edaradd EDAR associated via death domain (Synonyms: 1810032E07Rik, 5830469M23Rik, EDAR (ectodysplasin-A receptor)-associated death domain) | |
Results | Reference |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
Edil3 EGF-like repeats and discoidin I-like domains 3 (Synonyms: Del-1, Del1, developmental endothelial locus-1) | |
Results | Reference |
2 | J:134127 Hidai C, Kawana M, Habu K, Kazama H, Kawase Y, Iwata T, Suzuki H, Quertermous T, Kokubun S, Overexpression of the Del1 gene causes dendritic branching in the mouse mesentery. Anat Rec A Discov Mol Cell Evol Biol. 2005 Dec;287(2):1165-75 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Edn1 endothelin 1 (Synonyms: ET-1) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Edn3 endothelin 3 (Synonyms: 114-CH19, 114CH19, tmgc48) | |
Results | Reference |
1* | J:52925 Leibl MA, Ota T, Woodward MN, Kenny SE, Lloyd DA, Vaillant CR, Edgar DH, Expression of endothelin 3 by mesenchymal cells of embryonic mouse caecum [see comments]. Gut. 1999 Feb;44(2):246-52 |
Ednra endothelin receptor type A (Synonyms: AEA001, ETa, ET-AR, Gpcr10, Mhdaaea1) | |
Results | Reference |
1* | J:111223 Kitano Y, Kurihara H, Kurihara Y, Maemura K, Ryo Y, Yazaki Y, Harii K, Gene expression of bone matrix proteins and endothelin receptors in endothelin-1-deficient mice revealed by in situ hybridization. J Bone Miner Res. 1998 Feb;13(2):237-44 |
Ednrb endothelin receptor type B (Synonyms: ETb, ETR-b, Sox10m1) | |
Results | Reference |
1 | J:297312 Gillich A, Zhang F, Farmer CG, Travaglini KJ, Tan SY, Gu M, Zhou B, Feinstein JA, Krasnow MA, Metzger RJ, Capillary cell-type specialization in the alveolus. Nature. 2020 Oct;586(7831):785-789 |
1* | J:111223 Kitano Y, Kurihara H, Kurihara Y, Maemura K, Ryo Y, Yazaki Y, Harii K, Gene expression of bone matrix proteins and endothelin receptors in endothelin-1-deficient mice revealed by in situ hybridization. J Bone Miner Res. 1998 Feb;13(2):237-44 |
Eea1 early endosome antigen 1 (Synonyms: A430109M19Rik, B230358H09Rik, ZFYVE2) | |
Results | Reference |
1 | J:241068 Lucitti JL, Sealock R, Buckley BK, Zhang H, Xiao L, Dudley AC, Faber JE, Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke. Stroke. 2016 Dec;47(12):3022-3031 |
Eed embryonic ectoderm development (Synonyms: l(7)5Rn, l7Rn5) | |
Results | Reference |
1 | J:35419 Schumacher A, Faust C, Magnuson T, Positional cloning of a global regulator of anterior-posterior patterning in mice. Nature. 1996 Sep 19;383(6597):250-3 |
Eef1a1 eukaryotic translation elongation factor 1 alpha 1 (Synonyms: MGC:18758, MGC:27859, MGC:7551, MGC:8115, MGC:8209) | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Eef2 eukaryotic translation elongation factor 2 (Synonyms: Ef-2) | |
Results | Reference |
1 | J:349721 Borisova E, Newman AG, Couce Iglesias M, Dannenberg R, Schaub T, Qin B, Rusanova A, Brockmann M, Koch J, Daniels M, Turko P, Jahn O, Kaplan DR, Rosario M, Iwawaki T, Spahn CMT, Rosenmund C, Meierhofer D, Kraushar ML, Tarabykin V, Ambrozkiewicz MC, Protein translation rate determines neocortical neuron fate. Nat Commun. 2024 Jun 7;15(1):4879 |
Efcab7 EF-hand calcium binding domain 7 (Synonyms: MGC:28352) | |
Results | Reference |
1* | J:129949 Cui CY, Kunisada M, Esibizione D, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet. 2007 Nov 1;16(21):2583-90 |
Efemp1 epidermal growth factor-containing fibulin-like extracellular matrix protein 1 | |
Results | Reference |
1* | J:85715 Ehlermann J, Weber S, Pfisterer P, Schorle H, Cloning, expression and characterization of the murine Efemp1, a gene mutated in Doyne-Honeycomb retinal dystrophy. Gene Expr Patterns. 2003 Aug;3(4):441-7 |
Efemp2 epidermal growth factor-containing fibulin-like extracellular matrix protein 2 (Synonyms: 0610011K11Rik, Fbln4, fibulin 4, fibulin-4, MBP1) | |
Results | Reference |
1 | J:154659 Horiguchi M, Inoue T, Ohbayashi T, Hirai M, Noda K, Marmorstein LY, Yabe D, Takagi K, Akama TO, Kita T, Kimura T, Nakamura T, Fibulin-4 conducts proper elastogenesis via interaction with cross-linking enzyme lysyl oxidase. Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19029-34 |
Efna1 ephrin A1 (Synonyms: B61, EFL-1, Epl1, Eplg1, Lerk1, LERK-1) | |
Results | Reference |
1 | J:95080 Luukko K, Loes S, Kvinnsland IH, Kettunen P, Expression of ephrin-A ligands and EphA receptors in the developing mouse tooth and its supporting tissues. Cell Tissue Res. 2005 Jan;319(1):143-52 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1* | J:231672 Xavier GM, Miletich I, Cobourne MT, Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue. Front Physiol. 2016;7:60 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Efna2 ephrin A2 (Synonyms: Cek7-L, Elf-1, Ephrin-A2, ephrin A6, Epl6, LERK-6) | |
Results | Reference |
1* | J:79830 Garel S, Yun K, Grosschedl R, Rubenstein JL, The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development. 2002 Dec;129(24):5621-34 |
2 | J:256260 Homman-Ludiye J, Kwan WC, de Souza MJ, Rodger J, Bourne JA, Ephrin-A2 regulates excitatory neuron differentiation and interneuron migration in the developing neocortex. Sci Rep. 2017 Sep 18;7(1):11813 |
1 | J:95080 Luukko K, Loes S, Kvinnsland IH, Kettunen P, Expression of ephrin-A ligands and EphA receptors in the developing mouse tooth and its supporting tissues. Cell Tissue Res. 2005 Jan;319(1):143-52 |
1 | J:144134 Merrill AE, Bochukova EG, Brugger SM, Ishii M, Pilz DT, Wall SA, Lyons KM, Wilkie AO, Maxson RE Jr, Cell mixing at a neural crest-mesoderm boundary and deficient ephrin-Eph signaling in the pathogenesis of craniosynostosis. Hum Mol Genet. 2006 Apr 15;15(8):1319-28 |
1* | J:87768 Niederkofler V, Salie R, Sigrist M, Arber S, Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. J Neurosci. 2004 Jan 28;24(4):808-18 |
1 | J:153504 Torii M, Hashimoto-Torii K, Levitt P, Rakic P, Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling. Nature. 2009 Sep 24;461(7263):524-8 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1* | J:231672 Xavier GM, Miletich I, Cobourne MT, Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue. Front Physiol. 2016;7:60 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Efna3 ephrin A3 (Synonyms: EFL-2, Ehk1-L, Epl3, LERK-3) | |
Results | Reference |
1 | J:153504 Torii M, Hashimoto-Torii K, Levitt P, Rakic P, Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling. Nature. 2009 Sep 24;461(7263):524-8 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1* | J:231672 Xavier GM, Miletich I, Cobourne MT, Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue. Front Physiol. 2016;7:60 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Efna4 ephrin A4 (Synonyms: EFL-4, Epl4, LERK-4) | |
Results | Reference |
1 | J:144134 Merrill AE, Bochukova EG, Brugger SM, Ishii M, Pilz DT, Wall SA, Lyons KM, Wilkie AO, Maxson RE Jr, Cell mixing at a neural crest-mesoderm boundary and deficient ephrin-Eph signaling in the pathogenesis of craniosynostosis. Hum Mol Genet. 2006 Apr 15;15(8):1319-28 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Efna5 ephrin A5 (Synonyms: AL-1, EFL-5, Ephrin-A5, Epl7, LERK-7, RAGS) | |
Results | Reference |
1* | J:74241 Barbieri AM, Broccoli V, Bovolenta P, Alfano G, Marchitiello A, Mocchetti C, Crippa L, Bulfone A, Marigo V, Ballabio A, Banfi S, Vax2 inactivation in mouse determines alteration of the eye dorsal-ventral axis, misrouting of the optic fibres and eye coloboma. Development. 2002 Feb;129(3):805-13 |
2* | J:154889 Deschamps C, Faideau M, Jaber M, Gaillard A, Prestoz L, Expression of ephrinA5 during development and potential involvement in the guidance of the mesostriatal pathway. Exp Neurol. 2009 Oct;219(2):466-80 |
1* | J:334135 Deschamps C, Morel M, Janet T, Page G, Jaber M, Gaillard A, Prestoz L, EphrinA5 protein distribution in the developing mouse brain. BMC Neurosci. 2010 Aug 25;11:105 |
1* | J:184357 Dye CA, El Shawa H, Huffman KJ, A lifespan analysis of intraneocortical connections and gene expression in the mouse I. Cereb Cortex. 2011 Jun;21(6):1311-30 |
1* | J:79830 Garel S, Yun K, Grosschedl R, Rubenstein JL, The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development. 2002 Dec;129(24):5621-34 |
2 | J:217584 Gerstmann K, Pensold D, Symmank J, Khundadze M, Hubner CA, Bolz J, Zimmer G, Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions. Development. 2015 Jan 1;142(1):140-50 |
1 | J:81763 Hebert JM, Lin M, Partanen J, Rossant J, McConnell SK, FGF signaling through FGFR1 is required for olfactory bulb morphogenesis. Development. 2003 Mar;130(6):1101-11 |
1 | J:95080 Luukko K, Loes S, Kvinnsland IH, Kettunen P, Expression of ephrin-A ligands and EphA receptors in the developing mouse tooth and its supporting tissues. Cell Tissue Res. 2005 Jan;319(1):143-52 |
1* | J:87768 Niederkofler V, Salie R, Sigrist M, Arber S, Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. J Neurosci. 2004 Jan 28;24(4):808-18 |
1* | J:138785 Passante L, Gaspard N, Degraeve M, Frisen J, Kullander K, De Maertelaer V, Vanderhaeghen P, Temporal regulation of ephrin/Eph signalling is required for the spatial patterning of the mammalian striatum. Development. 2008 Oct;135(19):3281-90 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1 | J:153504 Torii M, Hashimoto-Torii K, Levitt P, Rakic P, Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling. Nature. 2009 Sep 24;461(7263):524-8 |
1 | J:180170 Triplett JW, Pfeiffenberger C, Yamada J, Stafford BK, Sweeney NT, Litke AM, Sher A, Koulakov AA, Feldheim DA, Competition is a driving force in topographic mapping. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19060-5 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
1 | J:144429 Yumoto N, Wakatsuki S, Kurisaki T, Hara Y, Osumi N, Frisen J, Sehara-Fujisawa A, Meltrin beta/ADAM19 interacting with EphA4 in developing neural cells participates in formation of the neuromuscular junction. PLoS One. 2008;3(10):e3322 |
Efnb1 ephrin B1 (Synonyms: Cek5-L, Cek5 ligand, EFL-3, Elk-L, Epl2, Eplg2, Lerk2, LERK-2, Stra1) | |
Results | Reference |
1* | J:60855 Birgbauer E, Cowan CA, Sretavan DW, Henkemeyer M, Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina. Development. 2000 Mar;127(6):1231-41 |
1* | J:150043 Bush JO, Soriano P, Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Genes Dev. 2009 Jul 1;23(13):1586-99 |
1 | J:68850 Lu Q, Sun EE, Klein RS, Flanagan JG, Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction. Cell. 2001 Apr 6;105(1):69-79 |
1 | J:104532 Mendes SW, Henkemeyer M, Liebl DJ, Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J Neurosci. 2006 Jan 18;26(3):882-92 |
2 | J:310398 Mire E, Hocine M, Bazellieres E, Jungas T, Davy A, Chauvet S, Mann F, Developmental Upregulation of Ephrin-B1 Silences Sema3C/Neuropilin-1 Signaling during Post-crossing Navigation of Corpus Callosum Axons. Curr Biol. 2018 Jun 4;28(11):1768-1782.e4 |
1* | J:37095 Orioli D, Henkemeyer M, Lemke G, Klein R, Pawson T, Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J. 1996 15;15(22):6035-49 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
2* | J:68841 Stuckmann I, Weigmann A, Shevchenko A, Mann M, Huttner WB, Ephrin B1 is expressed on neuroepithelial cells in correlation with neocortical neurogenesis. J Neurosci. 2001 Apr 15;21(8):2726-37 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
Efnb2 ephrin B2 (Synonyms: ELF-2, Epl5, Eplg5, Htk-L, Lerk5, LERK-5, NLERK-1) | |
Results | Reference |
1 | J:240790 Aghajanian H, Cho YK, Manderfield LJ, Herling MR, Gupta M, Ho VC, Li L, Degenhardt K, Aharonov A, Tzahor E, Epstein JA, Coronary vasculature patterning requires a novel endothelial ErbB2 holoreceptor. Nat Commun. 2016 Jun 30;7:12038 |
1* | J:74241 Barbieri AM, Broccoli V, Bovolenta P, Alfano G, Marchitiello A, Mocchetti C, Crippa L, Bulfone A, Marigo V, Ballabio A, Banfi S, Vax2 inactivation in mouse determines alteration of the eye dorsal-ventral axis, misrouting of the optic fibres and eye coloboma. Development. 2002 Feb;129(3):805-13 |
1* | J:60855 Birgbauer E, Cowan CA, Sretavan DW, Henkemeyer M, Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina. Development. 2000 Mar;127(6):1231-41 |
1 | J:315303 Bouche E, Romero-Ortega MI, Henkemeyer M, Catchpole T, Leemhuis J, Frotscher M, May P, Herz J, Bock HH, Reelin induces EphB activation. Cell Res. 2013 Apr;23(4):473-90 |
1 | J:267128 Chalothorn D, Faber JE, Formation and maturation of the native cerebral collateral circulation. J Mol Cell Cardiol. 2010 Aug;49(2):251-9 |
1 | J:179898 Coate TM, Raft S, Zhao X, Ryan AK, Crenshaw EB 3rd, Kelley MW, Otic Mesenchyme Cells Regulate Spiral Ganglion Axon Fasciculation through a Pou3f4/EphA4 Signaling Pathway. Neuron. 2012 Jan 12;73(1):49-63 |
1 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1 | J:157054 Egawa G, Osawa M, Uemura A, Miyachi Y, Nishikawa S, Transient expression of ephrin b2 in perinatal skin is required for maintenance of keratinocyte homeostasis. J Invest Dermatol. 2009 Oct;129(10):2386-95 |
1* | J:85445 Herrera E, Brown L, Aruga J, Rachel RA, Dolen G, Mikoshiba K, Brown S, Mason CA, Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell. 2003 Sep 5;114(5):545-57 |
1* | J:289438 Kischel A, Audouard C, Fawal MA, Davy A, Ephrin-B2 paces neuronal production in the developing neocortex. BMC Dev Biol. 2020 May 13;20(1):12 |
1 | J:194149 Le Bras B, Chatzopoulou E, Heydon K, Martinez S, Ikenaka K, Prestoz L, Spassky N, Zalc B, Thomas JL, Oligodendrocyte development in the embryonic brain: the contribution of the plp lineage. Int J Dev Biol. 2005;49(2-3):209-20 |
1 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
1 | J:119936 Manuel M, Georgala PA, Carr CB, Chanas S, Kleinjan DA, Martynoga B, Mason JO, Molinek M, Pinson J, Pratt T, Quinn JC, Simpson TI, Tyas DA, van Heyningen V, West JD, Price DJ, Controlled overexpression of Pax6 in vivo negatively autoregulates the Pax6 locus, causing cell-autonomous defects of late cortical progenitor proliferation with little effect on cortical arealization. Development. 2007 Feb;134(3):545-55 |
1* | J:284089 Mattiske D, Behringer RR, Overbeek PA, Pask AJ, A novel long non-coding RNA, Leat1, causes reduced anogenital distance and fertility in female mice. Differentiation. 2019 Dec 4;112:1-6 |
1 | J:104532 Mendes SW, Henkemeyer M, Liebl DJ, Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J Neurosci. 2006 Jan 18;26(3):882-92 |
1 | J:355222 Nord C, Jones I, Garcia-Maestre M, Hagglund AC, Carlsson L, Reduced mTORC1-signaling in progenitor cells leads to retinal lamination deficits. Dev Dyn. 2024 Oct;253(10):922-939 |
1* | J:37095 Orioli D, Henkemeyer M, Lemke G, Klein R, Pawson T, Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J. 1996 15;15(22):6035-49 |
1* | J:138785 Passante L, Gaspard N, Degraeve M, Frisen J, Kullander K, De Maertelaer V, Vanderhaeghen P, Temporal regulation of ephrin/Eph signalling is required for the spatial patterning of the mammalian striatum. Development. 2008 Oct;135(19):3281-90 |
1* | J:92062 Pratt T, Tian NM, Simpson TI, Mason JO, Price DJ, The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse. Development. 2004 Aug;131(15):3773-84 |
1 | J:223566 Raft S, Coate TM, Kelley MW, Crenshaw EB 3rd, Wu DK, Pou3f4-mediated regulation of ephrin-b2 controls temporal bone development in the mouse. PLoS One. 2014;9(10):e109043 |
1* | J:86844 Takahashi T, Takahashi K, Gerety S, Wang H, Anderson DJ, Daniel TO, Temporally compartmentalized expression of ephrin-B2 during renal glomerular development. J Am Soc Nephrol. 2001 Dec;12(12):2673-82 |
1 | J:299728 Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL, Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. Elife. 2019 Dec 4;8:e49977 |
1* | J:233757 Treffy RW, Collins D, Hoshino N, Ton S, Katsevman GA, Oleksiak M, Runge EM, Cho D, Russo M, Spec A, Gomulka J, Henkemeyer M, Rochlin MW, Ephrin-B/EphB Signaling Is Required for Normal Innervation of Lingual Gustatory Papillae. Dev Neurosci. 2016;38(2):124-38 |
1 | J:180170 Triplett JW, Pfeiffenberger C, Yamada J, Stafford BK, Sweeney NT, Litke AM, Sher A, Koulakov AA, Feldheim DA, Competition is a driving force in topographic mapping. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19060-5 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1* | J:231672 Xavier GM, Miletich I, Cobourne MT, Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue. Front Physiol. 2016;7:60 |
Efnb3 ephrin B3 (Synonyms: EFL-6, ELF-3, Elk-L3, Epl8, LERK-8, NLERK-2) | |
Results | Reference |
1 | J:315303 Bouche E, Romero-Ortega MI, Henkemeyer M, Catchpole T, Leemhuis J, Frotscher M, May P, Herz J, Bock HH, Reelin induces EphB activation. Cell Res. 2013 Apr;23(4):473-90 |
1 | J:104532 Mendes SW, Henkemeyer M, Liebl DJ, Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J Neurosci. 2006 Jan 18;26(3):882-92 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
Efs embryonal Fyn-associated substrate | |
Results | Reference |
1 | J:339438 Wong W, Estep JA, Treptow AM, Rajabli N, Jahncke JN, Ubina T, Wright KM, Riccomagno MM, An adhesion signaling axis involving Dystroglycan, beta1-Integrin, and Cas adaptor proteins regulates the establishment of the cortical glial scaffold. PLoS Biol. 2023 Aug;21(8):e3002212 |
Egf epidermal growth factor | |
Results | Reference |
1 | J:143845 Davy A, Soriano P, Ephrin-B2 forward signaling regulates somite patterning and neural crest cell development. Dev Biol. 2007 Apr 1;304(1):182-93 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
2 | J:38205 Kashimata M, Gresik EW, Epidermal growth factor system is a physiological regulator of development of the mouse fetal submandibular gland and regulates expression of the alpha6-integrin subunit. Dev Dyn. 1997 Feb;208(2):149-61 |
1* | J:70072 Kronmiller JE, Upholt WB, Kollar EJ, Expression of epidermal growth factor mRNA in the developing mouse mandibular process. Arch Oral Biol. 1991;36(6):405-10 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1* | J:130339 Minami S, Iwamoto R, Mekada E, HB-EGF decelerates cell proliferation synergistically with TGFalpha in perinatal distal lung development. Dev Dyn. 2008 Jan;237(1):247-58 |
1 | J:18097 Shigeta H, Taga M, Katoh A, Minaguchi H, Ontogenesis and Distribution of Epidermal Growth Factor Immunoreactivity and Binding Activity in the Mouse Fetal and Neonatal Tissues. Endocr J. 1993;40(6):641-647 |
1 | J:69793 Snead ML, Luo W, Oliver P, Nakamura M, Don-Wheeler G, Bessem C, Bell GI, Rall LB, Slavkin HC, Localization of epidermal growth factor precursor in tooth and lung during embryonic mouse development. Dev Biol. 1989 Aug;134(2):420-9 |
1 | J:93433 Weston CR, Wong A, Hall JP, Goad ME, Flavell RA, Davis RJ, The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis. Proc Natl Acad Sci U S A. 2004 Oct 28;101(39):14114-9 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Egfl6 EGF-like-domain, multiple 6 (Synonyms: Maeg) | |
Results | Reference |
1* | J:65644 Buchner G, Broccoli V, Bulfone A, Orfanelli U, Gattuso C, Ballabio A, Franco B, MAEG, an EGF-repeat containing gene, is a new marker associated with dermatome specification and morphogenesis of its derivatives. Mech Dev. 2000 Nov;98(1-2):179-82 |
2 | J:170886 Fujiwara H, Ferreira M, Donati G, Marciano DK, Linton JM, Sato Y, Hartner A, Sekiguchi K, Reichardt LF, Watt FM, The basement membrane of hair follicle stem cells is a muscle cell niche. Cell. 2011 Feb 18;144(4):577-89 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Egflam EGF-like, fibronectin type III and laminin G domains (Synonyms: nectican, pikachurin) | |
Results | Reference |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Egfr epidermal growth factor receptor (Synonyms: 9030024J15Rik, avian erythroblastic leukemia viral (v-erb-b) oncogene homolog, Erbb, Errb1, Wa5) | |
Results | Reference |
1* | J:36353 Berkowitz EA, Seroogy KB, Schroeder JA, Russell WE, Evans EP, Riedel RF, Phillips HK, Harrison CA, Lee DC, Luetteke NC, Characterization of the mouse transforming growth factor alpha gene: its expression during eyelid development and in waved 1 tissues. Cell Growth Differ. 1996 Sep;7(9):1271-82 |
1 | J:179734 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS, Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Dev Dyn. 2012 Feb;241(2):303-14 |
1 | J:141339 Dackor J, Strunk KE, Wehmeyer MM, Threadgill DW, Altered trophoblast proliferation is insufficient to account for placental dysfunction in Egfr null embryos. Placenta. 2007 Nov-Dec;28(11-12):1211-8 |
1* | J:356177 Ge W, Sun YC, Qiao T, Liu HX, He TR, Wang JJ, Chen CL, Cheng SF, Dyce PW, De Felici M, Shen W, Murine skin-derived multipotent papillary dermal fibroblast progenitors show germline potential in vitro. Stem Cell Res Ther. 2023 Feb 3;14(1):17 |
1* | J:44484 Gresik EW, Kashimata M, Kadoya Y, Mathews R, Minami N, Yamashina S, Expression of epidermal growth factor receptor in fetal mouse submandibular gland detected by a biotinyltyramide-based catalyzed signal amplification method. J Histochem Cytochem. 1997 Dec;45(12):1651-7 |
1 | J:306458 Jeong D, Lozano Casasbuenas D, Gengatharan A, Edwards K, Saghatelyan A, Kaplan DR, Miller FD, Yuzwa SA, LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex. Cell Rep. 2020 Oct 13;33(2):108257 |
1 | J:99502 Jimenez-Farfan D, Guevara J, Zenteno E, Malagon H, Hernandez-Guerrero JC, EGF-R and erbB-2 in murine tooth development after ethanol exposure. Birth Defects Res A Clin Mol Teratol. 2005 Feb;73(2):65-71 |
2 | J:38205 Kashimata M, Gresik EW, Epidermal growth factor system is a physiological regulator of development of the mouse fetal submandibular gland and regulates expression of the alpha6-integrin subunit. Dev Dyn. 1997 Feb;208(2):149-61 |
1* | J:200550 Le Pichon CE, Dominguez SL, Solanoy H, Ngu H, Lewin-Koh N, Chen M, Eastham-Anderson J, Watts R, Scearce-Levie K, EGFR inhibitor erlotinib delays disease progression but does not extend survival in the SOD1 mouse model of ALS. PLoS One. 2013;8(4):e62342 |
1 | J:348857 Li Z, Liu G, Yang L, Sun M, Zhang Z, Xu Z, Gao Y, Jiang X, Su Z, Li X, Yang Z, BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period. Protein Cell. 2024 Jan 3;15(1):21-35 |
1* | J:174485 Lillien L, Gulacsi A, Environmental signals elicit multiple responses in dorsal telencephalic progenitors by threshold-dependent mechanisms. Cereb Cortex. 2006 Jul;16 Suppl 1:i74-81 |
1 | J:163484 Lin MH, Chang KW, Lin SC, Miner JH, Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling. Dev Biol. 2010 Aug 15;344(2):707-19 |
1 | J:102070 Liu J, Nethery D, Kern JA, Neuregulin-1 induces branching morphogenesis in the developing lung through a P13K signal pathway. Exp Lung Res. 2004 Sep;30(6):465-78 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1* | J:77927 Muto S, Aiba A, Saito Y, Nakao K, Nakamura K, Tomita K, Kitamura T, Kurabayashi M, Nagai R, Higashihara E, Harris PC, Katsuki M, Horie S, Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant. Hum Mol Genet. 2002 Jul 15;11(15):1731-42 |
1 | J:187102 Ortega MC, Bribian A, Peregrin S, Gil MT, Marin O, de Castro F, Neuregulin-1/ErbB4 signaling controls the migration of oligodendrocyte precursor cells during development. Exp Neurol. 2012 Jun;235(2):610-20 |
1 | J:161760 Provost PR, Simard M, Tremblay Y, A link between lung androgen metabolism and the emergence of mature epithelial type II cells. Am J Respir Crit Care Med. 2004 Aug 1;170(3):296-305 |
1 | J:256217 Rubsam M, Mertz AF, Kubo A, Marg S, Jungst C, Goranci-Buzhala G, Schauss AC, Horsley V, Dufresne ER, Moser M, Ziegler W, Amagai M, Wickstrom SA, Niessen CM, E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning. Nat Commun. 2017 Nov 1;8(1):1250 |
1 | J:18097 Shigeta H, Taga M, Katoh A, Minaguchi H, Ontogenesis and Distribution of Epidermal Growth Factor Immunoreactivity and Binding Activity in the Mouse Fetal and Neonatal Tissues. Endocr J. 1993;40(6):641-647 |
1 | J:124878 Sierro F, Biben C, Martinez-Munoz L, Mellado M, Ransohoff RM, Li M, Woehl B, Leung H, Groom J, Batten M, Harvey RP, Martinez-A C, Mackay CR, Mackay F, Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14759-64 |
1 | J:178367 Slamon DJ, Cline MJ, Expression of cellular oncogenes during embryonic and fetal development of the mouse. Proc Natl Acad Sci U S A. 1984 Nov;81(22):7141-5 |
1 | J:354182 Sun M, Gao Y, Li Z, Yang L, Liu G, Xu Z, Guo R, You Y, Yang Z, ERK signaling expands mammalian cortical radial glial cells and extends the neurogenic period. Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2314802121 |
1 | J:93433 Weston CR, Wong A, Hall JP, Goad ME, Flavell RA, Davis RJ, The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis. Proc Natl Acad Sci U S A. 2004 Oct 28;101(39):14114-9 |
3 | J:225082 Zhang LJ, Bhattacharya S, Leid M, Ganguli-Indra G, Indra AK, Ctip2 is a dynamic regulator of epidermal proliferation and differentiation by integrating EGFR and Notch signaling. J Cell Sci. 2012 Dec 1;125(Pt 23):5733-44 |
Egln3 egl-9 family hypoxia-inducible factor 3 (Synonyms: 2610021G09Rik, Hif-p4h-3, Phd3, SM-20) | |
Results | Reference |
1* | J:60099 Moschella MC, Menzies K, Tsao L, Lieb MA, Kohtz JD, Kohtz DS, Taubman MB, SM-20 is a novel growth factor-responsive gene regulated during skeletal muscle development and differentiation. Gene Expr. 1999;8(1):59-66 |
Egr1 early growth response 1 (Synonyms: A530045N19Rik, Egr-1, ETR103, Krox-1, Krox-24, Krox24, NGF1-A, NGFI-A, NGFIA, TIS8, Zenk, Zfp-6, Zif268) | |
Results | Reference |
1 | J:71816 Ayadi A, Zheng H, Sobieszczuk P, Buchwalter G, Moerman P, Alitalo K, Wasylyk B, Net-targeted mutant mice develop a vascular phenotype and up-regulate egr-1. EMBO J. 2001 Sep 17;20(18):5139-52 |
1 | J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1 | J:279339 Hou PS, Miyoshi G, Hanashima C, Sensory cortex wiring requires preselection of short- and long-range projection neurons through an Egr-Foxg1-COUP-TFI network. Nat Commun. 2019 Aug 8;10(1):3581 |
1* | J:34982 Karavanova I, Vainio S, Thesleff I, Transient and recurrent expression of the Egr-1 gene in epithelial and mesenchymal cells during tooth morphogenesis suggests involvement in tissue interactions and in determination of cell fate. Mech Dev. 1992 Nov;39(1-2):41-50 |
1 | J:308781 Lejard V, Blais F, Guerquin MJ, Bonnet A, Bonnin MA, Havis E, Malbouyres M, Bidaud CB, Maro G, Gilardi-Hebenstreit P, Rossert J, Ruggiero F, Duprez D, EGR1 and EGR2 involvement in vertebrate tendon differentiation. J Biol Chem. 2011 Feb 18;286(7):5855-67 |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
1* | J:28114 Rackley RR, Kessler PM, Campbell C, Williams BR, In situ expression of the early growth response gene-1 during murine nephrogenesis. J Urol. 1995 Aug;154(2 Pt 2):700-5 |
1 | J:346405 Vitureira N, Andres R, Perez-Martinez E, Martinez A, Bribian A, Blasi J, Chelliah S, Lopez-Domenech G, De Castro F, Burgaya F, McNagny K, Soriano E, Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation. PLoS One. 2010 Aug 10;5(8):e12003 |
2 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
Egr2 early growth response 2 (Synonyms: Egr-2, Krox-20, Krox20, NGF1-B, Zfp-25) | |
Results | Reference |
1 | J:193143 Bouchoucha YX, Charnay P, Gilardi-Hebenstreit P, Ablation of Egr2-positive cells in male mouse anterior pituitary leads to atypical isolated GH deficiency. Endocrinology. 2013 Jan;154(1):270-82 |
1 | J:279339 Hou PS, Miyoshi G, Hanashima C, Sensory cortex wiring requires preselection of short- and long-range projection neurons through an Egr-Foxg1-COUP-TFI network. Nat Commun. 2019 Aug 8;10(1):3581 |
1 | J:308781 Lejard V, Blais F, Guerquin MJ, Bonnet A, Bonnin MA, Havis E, Malbouyres M, Bidaud CB, Maro G, Gilardi-Hebenstreit P, Rossert J, Ruggiero F, Duprez D, EGR1 and EGR2 involvement in vertebrate tendon differentiation. J Biol Chem. 2011 Feb 18;286(7):5855-67 |
1 | J:30822 Levi G, Topilko P, Schneider-Maunoury S, Lasagna M, Mantero S, Cancedda R, Charnay P, Defective bone formation in Krox-20 mutant mice. Development. 1996 Jan;122(1):113-20 |
1 | J:43515 Riethmacher D, Sonnenberg-Riethmacher E, Brinkmann V, Yamaai T , Lewin GR , Birchmeier C, Severe neuropathies in mice with targeted mutations in the ErbB3 receptor. Nature. 1997 Oct 16;389(6652):725-30 |
1* | J:9604 Wilkinson DG, Bhatt S, Chavrier P, Bravo R, Charnay P, Segment-specific expression of a zinc-finger gene in the developing nervous system of the mouse. Nature. 1989 Feb 2;337(6206):461-4 |
Egr3 early growth response 3 (Synonyms: Pilot) | |
Results | Reference |
1 | J:99702 Albert Y, Whitehead J, Eldredge L, Carter J, Gao X, Tourtellotte WG, Transcriptional regulation of myotube fate specification and intrafusal muscle fiber morphogenesis. J Cell Biol. 2005 Apr 25;169(2):257-68 |
1 | J:333392 Cao R, Chen P, Wang H, Jing H, Zhang H, Xing G, Luo B, Pan J, Yu Z, Xiong WC, Mei L, Intrafusal-fiber LRP4 for muscle spindle formation and maintenance in adult and aged animals. Nat Commun. 2023 Feb 10;14(1):744 |
1 | J:80793 Hippenmeyer S, Shneider NA, Birchmeier C, Burden SJ, Jessell TM, Arber S, A role for neuregulin1 signaling in muscle spindle differentiation. Neuron. 2002 Dec 19;36(6):1035-49 |
Ehd1 EH-domain containing 1 (Synonyms: Past1, RME-1) | |
Results | Reference |
1 | J:228518 Arya P, Rainey MA, Bhattacharyya S, Mohapatra BC, George M, Kuracha MR, Storck MD, Band V, Govindarajan V, Band H, The endocytic recycling regulatory protein EHD1 Is required for ocular lens development. Dev Biol. 2015 Dec 1;408(1):41-55 |
1* | J:259558 Bhattacharyya S, Rainey MA, Arya P, Dutta S, George M, Storck MD, McComb RD, Muirhead D, Todd GL, Gould K, Datta K, Gelineau-van Waes J, Band V, Band H, Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Sci Rep. 2016 Feb 17;6:20727 |
Ehd2 EH-domain containing 2 (Synonyms: C130052H20Rik, MGC:25606, MGC:38650) | |
Results | Reference |
1 | J:228518 Arya P, Rainey MA, Bhattacharyya S, Mohapatra BC, George M, Kuracha MR, Storck MD, Band V, Govindarajan V, Band H, The endocytic recycling regulatory protein EHD1 Is required for ocular lens development. Dev Biol. 2015 Dec 1;408(1):41-55 |
1* | J:259558 Bhattacharyya S, Rainey MA, Arya P, Dutta S, George M, Storck MD, McComb RD, Muirhead D, Todd GL, Gould K, Datta K, Gelineau-van Waes J, Band V, Band H, Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Sci Rep. 2016 Feb 17;6:20727 |
Ehd3 EH-domain containing 3 (Synonyms: Ehd2) | |
Results | Reference |
1 | J:228518 Arya P, Rainey MA, Bhattacharyya S, Mohapatra BC, George M, Kuracha MR, Storck MD, Band V, Govindarajan V, Band H, The endocytic recycling regulatory protein EHD1 Is required for ocular lens development. Dev Biol. 2015 Dec 1;408(1):41-55 |
1* | J:259558 Bhattacharyya S, Rainey MA, Arya P, Dutta S, George M, Storck MD, McComb RD, Muirhead D, Todd GL, Gould K, Datta K, Gelineau-van Waes J, Band V, Band H, Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Sci Rep. 2016 Feb 17;6:20727 |
Ehd4 EH-domain containing 4 (Synonyms: 2210022F10Rik) | |
Results | Reference |
1 | J:228518 Arya P, Rainey MA, Bhattacharyya S, Mohapatra BC, George M, Kuracha MR, Storck MD, Band V, Govindarajan V, Band H, The endocytic recycling regulatory protein EHD1 Is required for ocular lens development. Dev Biol. 2015 Dec 1;408(1):41-55 |
1* | J:259558 Bhattacharyya S, Rainey MA, Arya P, Dutta S, George M, Storck MD, McComb RD, Muirhead D, Todd GL, Gould K, Datta K, Gelineau-van Waes J, Band V, Band H, Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development. Sci Rep. 2016 Feb 17;6:20727 |
Ehmt1 euchromatic histone methyltransferase 1 (Synonyms: 9230102N17Rik, KMT1D, mKIAA1876) | |
Results | Reference |
1 | J:173973 Benlhabib H, Mendelson CR, Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia. Mol Cell Biol. 2011 May;31(10):1949-58 |
2 | J:194500 Deguchi K, Nagamatsu G, Miyachi H, Kato Y, Morita S, Kimura H, Kitano S, Hatada I, Saga Y, Tachibana M, Shinkai Y, Posttranscriptional regulation of histone lysine methyltransferase GLP in embryonic male mouse germ cells. Biol Reprod. 2013 Feb;88(2):36 |
3* | J:194983 Ideno H, Shimada A, Imaizumi K, Kimura H, Abe M, Nakashima K, Nifuji A, Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development. Gene Expr Patterns. 2013 Mar-Apr;13(3-4):84-90 |
1 | J:204470 Inagawa M, Nakajima K, Makino T, Ogawa S, Kojima M, Ito S, Ikenishi A, Hayashi T, Schwartz RJ, Nakamura K, Obayashi T, Tachibana M, Shinkai Y, Maeda K, Miyagawa-Tomita S, Takeuchi T, Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis. Mech Dev. 2013 Nov-Dec;130(11-12):519-31 |
Ehmt2 euchromatic histone lysine N-methyltransferase 2 (Synonyms: Bat8, D17Ertd710e, G9a, KMT1C, NG36) | |
Results | Reference |
1 | J:173973 Benlhabib H, Mendelson CR, Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia. Mol Cell Biol. 2011 May;31(10):1949-58 |
1 | J:194500 Deguchi K, Nagamatsu G, Miyachi H, Kato Y, Morita S, Kimura H, Kitano S, Hatada I, Saga Y, Tachibana M, Shinkai Y, Posttranscriptional regulation of histone lysine methyltransferase GLP in embryonic male mouse germ cells. Biol Reprod. 2013 Feb;88(2):36 |
1* | J:292270 Ideno H, Nakashima K, Komatsu K, Araki R, Abe M, Arai Y, Kimura H, Shinkai Y, Tachibana M, Nifuji A, G9a is involved in the regulation of cranial bone formation through activation of Runx2 function during development. Bone. 2020 Aug;137:115332 |
3* | J:194983 Ideno H, Shimada A, Imaizumi K, Kimura H, Abe M, Nakashima K, Nifuji A, Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development. Gene Expr Patterns. 2013 Mar-Apr;13(3-4):84-90 |
1 | J:204470 Inagawa M, Nakajima K, Makino T, Ogawa S, Kojima M, Ito S, Ikenishi A, Hayashi T, Schwartz RJ, Nakamura K, Obayashi T, Tachibana M, Shinkai Y, Maeda K, Miyagawa-Tomita S, Takeuchi T, Histone H3 lysine 9 methyltransferases, G9a and GLP are essential for cardiac morphogenesis. Mech Dev. 2013 Nov-Dec;130(11-12):519-31 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
1* | J:320688 Wada S, Ideno H, Shimada A, Kamiunten T, Nakamura Y, Nakashima K, Kimura H, Shinkai Y, Tachibana M, Nifuji A, H3K9MTase G9a is essential for the differentiation and growth of tenocytes in vitro. Histochem Cell Biol. 2015 Jul;144(1):13-20 |
Eif1b eukaryotic translation initiation factor 1B (Synonyms: 1500010M16Rik, 3110001N14Rik) | |
Results | Reference |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Eif2a eukaryotic translation initiation factor 2A (Synonyms: D3Ertd194e) | |
Results | Reference |
1 | J:158314 Firtina Z, Danysh BP, Bai X, Gould DB, Kobayashi T, Duncan MK, Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract. J Biol Chem. 2009 Dec 18;284(51):35872-84 |
1* | J:168632 Firtina Z, Duncan MK, Unfolded Protein Response (UPR) is activated during normal lens development. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):135-43 |
1 | J:158241 Saito A, Hino S, Murakami T, Kanemoto S, Kondo S, Saitoh M, Nishimura R, Yoneda T, Furuichi T, Ikegawa S, Ikawa M, Okabe M, Imaizumi K, Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis. Nat Cell Biol. 2009 Oct;11(10):1197-204 |
1 | J:206302 Saito A, Kanemoto S, Zhang Y, Asada R, Hino K, Imaizumi K, Chondrocyte proliferation regulated by secreted luminal domain of ER stress transducer BBF2H7/CREB3L2. Mol Cell. 2014 Jan 9;53(1):127-39 |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
1 | J:342871 Xiang J, Pompetti AJ, Faranda AP, Wang Y, Novo SG, Li DW, Duncan MK, ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment. Cells. 2023 Nov 16;12(22) |
1 | J:128422 Zhang X, Szabo E, Michalak M, Opas M, Endoplasmic reticulum stress during the embryonic development of the central nervous system in the mouse. Int J Dev Neurosci. 2007 Nov;25(7):455-63 |
Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 (Synonyms: PERK) | |
Results | Reference |
2* | J:294896 Aryal YP, Lee ES, Kim TY, Sung S, Kim JY, An SY, Jung JK, Ha JH, Suh JY, Yamamoto H, Sohn WJ, Cho SW, Lee Y, An CH, Kim JY, Stage-specific expression patterns of ER stress-related molecules in mice molars: Implications for tooth development. Gene Expr Patterns. 2020 Sep;37:119130 |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
1 | J:158314 Firtina Z, Danysh BP, Bai X, Gould DB, Kobayashi T, Duncan MK, Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract. J Biol Chem. 2009 Dec 18;284(51):35872-84 |
1* | J:168632 Firtina Z, Duncan MK, Unfolded Protein Response (UPR) is activated during normal lens development. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):135-43 |
Eif3c eukaryotic translation initiation factor 3, subunit C (Synonyms: 110kDa, 3230401O13Rik, Eif3s8, NIPIL(A3), Xs, Xsl) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Eif3h eukaryotic translation initiation factor 3, subunit H (Synonyms: 1110008A16Rik, 9430017H16Rik, EIF3-gamma, EIF3-P40, Eif3s3) | |
Results | Reference |
1* | J:344233 Wu C, Liu H, Zhan Z, Zhang X, Zhang M, You J, Ma J, Unveiling dysregulated lncRNAs and networks in non-syndromic cleft lip with or without cleft palate pathogenesis. Sci Rep. 2024 Jan 10;14(1):1047 |
Eif3i eukaryotic translation initiation factor 3, subunit I (Synonyms: 36kDa, D4Ertd632e, Eif3s2, TRIP-1) | |
Results | Reference |
1* | J:196769 Ramachandran A, Ravindran S, George A, Localization of transforming growth factor beta receptor II interacting protein-1 in bone and teeth: implications in matrix mineralization. J Histochem Cytochem. 2012 Apr;60(4):323-37 |
Eif3k eukaryotic translation initiation factor 3, subunit K (Synonyms: 1200009C21Rik, eIF3K, Eif3s12) | |
Results | Reference |
1* | J:356303 Zhao Y, Zheng D, Cvekl A, A comprehensive spatial-temporal transcriptomic analysis of differentiating nascent mouse lens epithelial and fiber cells. Exp Eye Res. 2018 Oct;175:56-72 |
Eif4a1 eukaryotic translation initiation factor 4A1 (Synonyms: Eif4, initiation factor eIF-4A long form) | |
Results | Reference |
1 | J:349721 Borisova E, Newman AG, Couce Iglesias M, Dannenberg R, Schaub T, Qin B, Rusanova A, Brockmann M, Koch J, Daniels M, Turko P, Jahn O, Kaplan DR, Rosario M, Iwawaki T, Spahn CMT, Rosenmund C, Meierhofer D, Kraushar ML, Tarabykin V, Ambrozkiewicz MC, Protein translation rate determines neocortical neuron fate. Nat Commun. 2024 Jun 7;15(1):4879 |
1* | J:299510 Wang JJ, Ge W, Zhai QY, Liu JC, Sun XW, Liu WX, Li L, Lei CZ, Dyce PW, De Felici M, Shen W, Single-cell transcriptome landscape of ovarian cells during primordial follicle assembly in mice. PLoS Biol. 2020 Dec;18(12):e3001025 |
Eif4ebp1 eukaryotic translation initiation factor 4E binding protein 1 (Synonyms: 4e-bp1, PHAS-I) | |
Results | Reference |
1 | J:242729 Ding X, Bloch W, Iden S, Ruegg MA, Hall MN, Leptin M, Partridge L, Eming SA, mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation. Nat Commun. 2016 Oct 27;7:13226 |
1 | J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410 |
1 | J:309451 Vinsland E, Baskaran P, Mihaylov SR, Hobbs C, Wood H, Bouybayoune I, Shah K, Houart C, Tee AR, Murn J, Fernandes C, Bateman JM, The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021 Aug 11;11(1):16299 |
Eif4ebp2 eukaryotic translation initiation factor 4E binding protein 2 (Synonyms: 2810011I19Rik, 4E-BP2, PHAS-II) | |
Results | Reference |
1 | J:309451 Vinsland E, Baskaran P, Mihaylov SR, Hobbs C, Wood H, Bouybayoune I, Shah K, Houart C, Tee AR, Murn J, Fernandes C, Bateman JM, The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021 Aug 11;11(1):16299 |
Eif4enif1 eukaryotic translation initiation factor 4E nuclear import factor 1 (Synonyms: 2610509L04Rik, A930019J01Rik, Clast4, D11Ertd166e) | |
Results | Reference |
1 | J:343469 Ding Y, He Z, Sha Y, Kee K, Li L, Eif4enif1 haploinsufficiency disrupts oocyte mitochondrial dynamics and leads to subfertility. Development. 2023 Dec 1;150(23):dev202151 |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Eif5a eukaryotic translation initiation factor 5A (Synonyms: D19Wsu54e) | |
Results | Reference |
2* | J:163363 Parreiras-E-Silva LT, Luchessi AD, Reis RI, Oliver C, Jamur MC, Ramos RG, Oliveira EB, Curi R, Costa-Neto CM, Evidences of a role for eukaryotic translation initiation factor 5A (eIF5A) in mouse embryogenesis and cell differentiation. J Cell Physiol. 2010 Nov;225(2):500-5 |
Elac2 elaC ribonuclease Z 2 (Synonyms: 1110017O07Rik, D11Wsu80e, tRNase Z(L)) | |
Results | Reference |
1* | J:333712 Liang J, Liang J, Tan Q, Wang Z, ELAC2 Functions as a Key Gene in the Early Development of Placental Formation Based on WGCNA. Cells. 2023 Feb 14;12(4) |
Elapor1 endosome-lysosome associated apoptosis and autophagy regulator 1 (Synonyms: 5330417C22Rik, Iir, Inceptor) | |
Results | Reference |
1 | J:305792 Ansarullah, Jain C, Far FF, Homberg S, Wissmiller K, von Hahn FG, Raducanu A, Schirge S, Sterr M, Bilekova S, Siehler J, Wiener J, Oppenlander L, Morshedi A, Bastidas-Ponce A, Collden G, Irmler M, Beckers J, Feuchtinger A, Grzybek M, Ahlbrecht C, Feederle R, Plettenburg O, Muller TD, Meier M, Tschop MH, Coskun U, Lickert H, Inceptor counteracts insulin signalling in beta-cells to control glycaemia. Nature. 2021 Feb;590(7845):326-331 |
Elavl1 ELAV like RNA binding protein 1 (Synonyms: 2410055N02Rik, ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R), Hua, HuR, W91709) | |
Results | Reference |
2* | J:66029 Gouble A, Morello D, Synchronous and regulated expression of two AU-binding proteins, AUF1 and HuR, throughout murine development. Oncogene. 2000 Nov 9;19(47):5377-84 |
1* | J:234972 McDermott BT, Ellis S, Bou-Gharios G, Clegg PD, Tew SR, RNA binding proteins regulate anabolic and catabolic gene expression in chondrocytes. Osteoarthritis Cartilage. 2016 Jul;24(7):1263-73 |
1* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
2 | J:341968 Weber AI, Parthasarathy S, Borisova E, Epifanova E, Preussner M, Rusanova A, Ambrozkiewicz MC, Bessa P, Newman AG, Muller L, Schaal H, Heyd F, Tarabykin V, Srsf1 and Elavl1 act antagonistically on neuronal fate choice in the developing neocortex by controlling TrkC receptor isoform expression. Nucleic Acids Res. 2023 Oct 27;51(19):10218-10237 |
Elavl2 ELAV like RNA binding protein 1 (Synonyms: Hub, mel-N1) | |
Results | Reference |
1 | J:282136 Kato Y, Iwamori T, Ninomiya Y, Kohda T, Miyashita J, Sato M, Saga Y, ELAVL2-directed RNA regulatory network drives the formation of quiescent primordial follicles. EMBO Rep. 2019 Dec 5;20(12):e48251 |
1 | J:187391 Pacal M, Bremner R, Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Dev Dyn. 2012 Oct;241(10):1525-44 |
1* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
2 | J:307191 Wu M, Deng Q, Lei X, Du Y, Shen Y, Elavl2 Regulates Retinal Function Via Modulating the Differentiation of Amacrine Cells Subtype. Invest Ophthalmol Vis Sci. 2021 Jun 1;62(7):1 |
2 | J:354849 Wutikeli H, Yu Y, Zhang T, Cao J, Nawy S, Shen Y, Role of Elavl-like RNA-binding protein in retinal development and signal transduction. Biochim Biophys Acta Mol Basis Dis. 2024 Sep 20;1871(1):167518 |
Elavl3 ELAV like RNA binding protein 3 (Synonyms: 2600009P04Rik, Huc, mHuC) | |
Results | Reference |
1 | J:237540 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R, The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development. 2016 Nov 15;143(22):4182-4192 |
1 | J:330584 Hamnett R, Dershowitz LB, Sampathkumar V, Wang Z, Gomez-Frittelli J, De Andrade V, Kasthuri N, Druckmann S, Kaltschmidt JA, Regional cytoarchitecture of the adult and developing mouse enteric nervous system. Curr Biol. 2022 Oct 24;32(20):4483-4492.e5 |
1 | J:306265 Hao MM, Fung C, Boesmans W, Lowette K, Tack J, Vanden Berghe P, Development of the intrinsic innervation of the small bowel mucosa and villi. Am J Physiol Gastrointest Liver Physiol. 2020 Jan 1;318(1):G53-G65 |
1 | J:308791 Kameneva P, Artemov AV, Kastriti ME, Faure L, Olsen TK, Otte J, Erickson A, Semsch B, Andersson ER, Ratz M, Frisen J, Tischler AS, de Krijger RR, Bouderlique T, Akkuratova N, Vorontsova M, Gusev O, Fried K, Sundstrom E, Mei S, Kogner P, Baryawno N, Kharchenko PV, Adameyko I, Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin. Nat Genet. 2021 May;53(5):694-706 |
1 | J:330583 McKey J, Anbarci DN, Bunce C, Ontiveros AE, Behringer RR, Capel B, Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii. Elife. 2022 Sep 27;11:e81088 |
1 | J:273473 McKey J, Bunce C, Batchvarov IS, Ornitz DM, Capel B, Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5570-5575 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:332403 Miller SR, Perera SN, Benito C, Stott SR, Baker CV, Evidence for a Notch1-mediated transition during olfactory ensheathing cell development. J Anat. 2016 Sep;229(3):369-83 |
1 | J:187391 Pacal M, Bremner R, Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Dev Dyn. 2012 Oct;241(10):1525-44 |
1 | J:155110 Puig I, Champeval D, De Santa Barbara P, Jaubert F, Lyonnet S, Larue L, Deletion of Pten in the mouse enteric nervous system induces ganglioneuromatosis and mimics intestinal pseudoobstruction. J Clin Invest. 2009 Dec;119(12):3586-96 |
Elavl4 ELAV like RNA binding protein 4 (Synonyms: Hud) | |
Results | Reference |
1 | J:217584 Gerstmann K, Pensold D, Symmank J, Khundadze M, Hubner CA, Bolz J, Zimmer G, Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions. Development. 2015 Jan 1;142(1):140-50 |
1 | J:330584 Hamnett R, Dershowitz LB, Sampathkumar V, Wang Z, Gomez-Frittelli J, De Andrade V, Kasthuri N, Druckmann S, Kaltschmidt JA, Regional cytoarchitecture of the adult and developing mouse enteric nervous system. Curr Biol. 2022 Oct 24;32(20):4483-4492.e5 |
1 | J:306265 Hao MM, Fung C, Boesmans W, Lowette K, Tack J, Vanden Berghe P, Development of the intrinsic innervation of the small bowel mucosa and villi. Am J Physiol Gastrointest Liver Physiol. 2020 Jan 1;318(1):G53-G65 |
1 | J:308791 Kameneva P, Artemov AV, Kastriti ME, Faure L, Olsen TK, Otte J, Erickson A, Semsch B, Andersson ER, Ratz M, Frisen J, Tischler AS, de Krijger RR, Bouderlique T, Akkuratova N, Vorontsova M, Gusev O, Fried K, Sundstrom E, Mei S, Kogner P, Baryawno N, Kharchenko PV, Adameyko I, Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin. Nat Genet. 2021 May;53(5):694-706 |
1 | J:330583 McKey J, Anbarci DN, Bunce C, Ontiveros AE, Behringer RR, Capel B, Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii. Elife. 2022 Sep 27;11:e81088 |
1 | J:273473 McKey J, Bunce C, Batchvarov IS, Ornitz DM, Capel B, Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5570-5575 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:332403 Miller SR, Perera SN, Benito C, Stott SR, Baker CV, Evidence for a Notch1-mediated transition during olfactory ensheathing cell development. J Anat. 2016 Sep;229(3):369-83 |
1 | J:187391 Pacal M, Bremner R, Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Dev Dyn. 2012 Oct;241(10):1525-44 |
1 | J:155110 Puig I, Champeval D, De Santa Barbara P, Jaubert F, Lyonnet S, Larue L, Deletion of Pten in the mouse enteric nervous system induces ganglioneuromatosis and mimics intestinal pseudoobstruction. J Clin Invest. 2009 Dec;119(12):3586-96 |
2 | J:354849 Wutikeli H, Yu Y, Zhang T, Cao J, Nawy S, Shen Y, Role of Elavl-like RNA-binding protein in retinal development and signal transduction. Biochim Biophys Acta Mol Basis Dis. 2024 Sep 20;1871(1):167518 |
Elf3 E74-like factor 3 (Synonyms: ESE-1, ESX, jen) | |
Results | Reference |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
1* | J:65402 Yoshida N, Yoshida S, Araie M, Handa H, Nabeshima Y, Ets family transcription factor ESE-1 is expressed in corneal epithelial cells and is involved in their differentiation. Mech Dev. 2000 Oct;97(1-2):27-34 |
Elf5 E74-like factor 5 (Synonyms: ESE-2) | |
Results | Reference |
1 | J:241013 Grassmeyer J, Mukherjee M, deRiso J, Hettinger C, Bailey M, Sinha S, Visvader JE, Zhao H, Fogarty E, Surendran K, Elf5 is a principal cell lineage specific transcription factor in the kidney that contributes to Aqp2 and Avpr2 gene expression. Dev Biol. 2017 Apr 01;424(1):77-89 |
2* | J:266596 Kersbergen A, Best SA, Dworkin S, Ah-Cann C, de Vries ME, Asselin-Labat ML, Ritchie ME, Jane SM, Sutherland KD, Lung morphogenesis is orchestrated through Grainyhead-like 2 (Grhl2) transcriptional programs. Dev Biol. 2018 Nov 1;443(1):1-9 |
1 | J:139210 Metzger DE, Stahlman MT, Shannon JM, Misexpression of ELF5 disrupts lung branching and inhibits epithelial differentiation. Dev Biol. 2008 Aug 1;320(1):149-60 |
1* | J:120879 Metzger DE, Xu Y, Shannon JM, Elf5 is an epithelium-specific, fibroblast growth factor-sensitive transcription factor in the embryonic lung. Dev Dyn. 2007 May;236(5):1175-92 |
2 | J:356957 Rogers RL, Van Seuningen I, Gould J, Hertzog PJ, Naylor MJ, Pritchard MA, Transcript profiling of Elf5+/- mammary glands during pregnancy identifies novel targets of Elf5. PLoS One. 2010 Oct 7;5(10):e13150 |
1 | J:182938 Sevilla LM, Bayo P, Latorre V, Sanchis A, Perez P, Glucocorticoid receptor regulates overlapping and differential gene subsets in developing and adult skin. Mol Endocrinol. 2010 Nov;24(11):2166-78 |
Elk1 ELK1, member of ETS oncogene family (Synonyms: Elk-1) | |
Results | Reference |
1 | J:216228 Inoue S, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y, New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet. 2014 Dec 15;23(24):6553-66 |
1 | J:161774 Wang S, Turner EE, Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity. J Neurosci. 2010 Jul 7;30(27):9224-7 |
Elk3 ELK3, member of ETS oncogene family (Synonyms: D430049E23Rik, Erp, Net, Sap-2) | |
Results | Reference |
1* | J:69389 Ayadi A, Suelves M, Dolle P, Wasylyk B, Net, an Ets ternary complex transcription factor, is expressed in sites of vasculogenesis, angiogenesis, and chondrogenesis during mouse development. Mech Dev. 2001 Apr;102(1-2):205-8 |
2 | J:71816 Ayadi A, Zheng H, Sobieszczuk P, Buchwalter G, Moerman P, Alitalo K, Wasylyk B, Net-targeted mutant mice develop a vascular phenotype and up-regulate egr-1. EMBO J. 2001 Sep 17;20(18):5139-52 |
Ell elongation factor RNA polymerase II (Synonyms: eleven-nineteen lysine-rich leukemia gene, Ell1, Men) | |
Results | Reference |
1* | J:38608 Thirman MJ, Diskin EB, Bin SS, Ip HS, Miller JM, Simon MC, Developmental analysis and subcellular localization of the murine homologue of ELL. Proc Natl Acad Sci U S A. 1997 Feb 18;94(4):1408-13 |
Elmo1 engulfment and cell motility 1 (Synonyms: 6330578D22Rik, C230095H21Rik, CED-12) | |
Results | Reference |
1 | J:126582 Cobos I, Borello U, Rubenstein JL, Dlx transcription factors promote migration through repression of axon and dendrite growth. Neuron. 2007 Jun 21;54(6):873-88 |
Eln elastin (Synonyms: E030024M20Rik, tropoelastin) | |
Results | Reference |
1 | J:159978 Gao Z, Kim GH, Mackinnon AC, Flagg AE, Bassett B, Earley JU, Svensson EC, Ets1 is required for proper migration and differentiation of the cardiac neural crest. Development. 2010 May;137(9):1543-51 |
1* | J:85546 Gill SE, Pape MC, Khokha R, Watson AJ, Leco KJ, A null mutation for tissue inhibitor of metalloproteinases-3 (Timp-3) impairs murine bronchiole branching morphogenesis. Dev Biol. 2003 Sep 15;261(2):313-23 |
2 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
2 | J:195895 Hanson KP, Jung JP, Tran QA, Hsu SP, Iida R, Ajeti V, Campagnola PJ, Eliceiri KW, Squirrell JM, Lyons GE, Ogle BM, Spatial and temporal analysis of extracellular matrix proteins in the developing murine heart: a blueprint for regeneration. Tissue Eng Part A. 2013 May;19(9-10):1132-43 |
1* | J:267460 Hrycaj SM, Marty-Santos L, Cebrian C, Rasky AJ, Ptaschinski C, Lukacs NW, Wellik DM, Hox5 genes direct elastin network formation during alveologenesis by regulating myofibroblast adhesion. Proc Natl Acad Sci U S A. 2018 Nov 6;115(45):E10605-E10614 |
1* | J:43767 Lindahl P, Karlsson L, Hellstrom M, Gebre-Medhin S, Willetts K, Heath JK, Betsholtz C, Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development. Development. 1997 Oct;124(20):3943-53 |
1 | J:357839 Nasim S, Abujamra BA, Chaparro D, Nogueira PDS, Riva A, Hutcheson JD, Kos L, Multiple cell types including melanocytes contribute to elastogenesis in the developing murine aortic valve. Sci Rep. 2024 Oct 26;14(1):25481 |
1* | J:110736 Wendel DP, Taylor DG, Albertine KH, Keating MT, Li DY, Impaired distal airway development in mice lacking elastin. Am J Respir Cell Mol Biol. 2000 Sep;23(3):320-6 |
1* | J:341382 Wu B, Wu B, Benkaci S, Shi L, Lu P, Park T, Morrow BE, Wang Y, Zhou B, Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development. J Am Heart Assoc. 2023 Sep 19;12(18):e029683 |
Eloa elongin A (Synonyms: Tceb3) | |
Results | Reference |
1* | J:119126 Miyata K, Yasukawa T, Fukuda M, Takeuchi T, Yamazaki K, Sakumi K, Tamamori-Adachi M, Ohnishi Y, Ohtsuki Y, Nakabeppu Y, Kitajima S, Onishi S, Aso T, Induction of apoptosis and cellular senescence in mice lacking transcription elongation factor, Elongin A. Cell Death Differ. 2007 Apr;14(4):716-26 |
Elob elongin B (Synonyms: 0610040H15Rik, 18 kDa, elongin B, Tceb2) | |
Results | Reference |
1 | J:158726 Campos Y, Qiu X, Zanoteli E, Moshiach S, Vergani N, Bongiovanni A, Harris AJ, d'Azzo A, Ozz-E3 ubiquitin ligase targets sarcomeric embryonic myosin heavy chain during muscle development. PLoS One. 2010;5(3):e9866 |
Eloc elongin C (Synonyms: 2610301I15Rik, Tceb1) | |
Results | Reference |
1 | J:158726 Campos Y, Qiu X, Zanoteli E, Moshiach S, Vergani N, Bongiovanni A, Harris AJ, d'Azzo A, Ozz-E3 ubiquitin ligase targets sarcomeric embryonic myosin heavy chain during muscle development. PLoS One. 2010;5(3):e9866 |
Elovl3 ELOVL fatty acid elongase 3 (Synonyms: Cig30, CIN-2, elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3) | |
Results | Reference |
1 | J:324530 Fonseca TL, Russo SC, Luongo C, Salvatore D, Bianco AC, Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 May 1;163(5) |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
Elp1 elongator complex protein 1 (Synonyms: 3110040G09Rik, C78473, IKAP, Ikbkap) | |
Results | Reference |
1 | J:360776 Di Michele M, Attina A, Roux PF, Tabet I, Laguesse S, Florido J, Houdeville M, Choquet A, Encislai B, Arena G, De Blasio C, Wendling O, Frenois FX, Papon L, Stuani L, Fuentes M, Jahannault Talignani C, Rousseau M, Guegan J, Buscail Y, Dupre P, Michaud HA, Rodier G, Bellvert F, Kulyk H, Ferraro Peyret C, Mathieu H, Close P, Rapino F, Chaveroux C, Pirot N, Rubio L, Torro A, Sorg T, Ango F, Hirtz C, Compan V, Lebigot E, Legati A, Ghezzi D, Nguyen L, David A, Sardet C, Lacroix M, Le Cam L, E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development. Nat Commun. 2025 Jan 2;16(1):67 |
1* | J:188923 Dietrich P, Alli S, Shanmugasundaram R, Dragatsis I, IKAP expression levels modulate disease severity in a mouse model of familial dysautonomia. Hum Mol Genet. 2012 Dec 1;21(23):5078-90 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
Elp2 elongator acetyltransferase complex subunit 2 (Synonyms: Stat3-interacting protein, Statip1, StIP1) | |
Results | Reference |
1 | J:360776 Di Michele M, Attina A, Roux PF, Tabet I, Laguesse S, Florido J, Houdeville M, Choquet A, Encislai B, Arena G, De Blasio C, Wendling O, Frenois FX, Papon L, Stuani L, Fuentes M, Jahannault Talignani C, Rousseau M, Guegan J, Buscail Y, Dupre P, Michaud HA, Rodier G, Bellvert F, Kulyk H, Ferraro Peyret C, Mathieu H, Close P, Rapino F, Chaveroux C, Pirot N, Rubio L, Torro A, Sorg T, Ango F, Hirtz C, Compan V, Lebigot E, Legati A, Ghezzi D, Nguyen L, David A, Sardet C, Lacroix M, Le Cam L, E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development. Nat Commun. 2025 Jan 2;16(1):67 |
Elp3 elongator acetyltransferase complex subunit 3 (Synonyms: 2610507P14Rik, KAT9) | |
Results | Reference |
1 | J:360776 Di Michele M, Attina A, Roux PF, Tabet I, Laguesse S, Florido J, Houdeville M, Choquet A, Encislai B, Arena G, De Blasio C, Wendling O, Frenois FX, Papon L, Stuani L, Fuentes M, Jahannault Talignani C, Rousseau M, Guegan J, Buscail Y, Dupre P, Michaud HA, Rodier G, Bellvert F, Kulyk H, Ferraro Peyret C, Mathieu H, Close P, Rapino F, Chaveroux C, Pirot N, Rubio L, Torro A, Sorg T, Ango F, Hirtz C, Compan V, Lebigot E, Legati A, Ghezzi D, Nguyen L, David A, Sardet C, Lacroix M, Le Cam L, E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development. Nat Commun. 2025 Jan 2;16(1):67 |
1 | J:280869 Freeman S, Mateo Sanchez S, Pouyo R, Van Lerberghe PB, Hanon K, Thelen N, Thiry M, Morelli G, Van Hees L, Laguesse S, Chariot A, Nguyen L, Delacroix L, Malgrange B, Proteostasis is essential during cochlear development for neuron survival and hair cell polarity. EMBO Rep. 2019 Sep;20(9):e47097 |
Elp4 elongator acetyltransferase complex subunit 4 (Synonyms: A330107A17Rik, Paxneb) | |
Results | Reference |
1 | J:360776 Di Michele M, Attina A, Roux PF, Tabet I, Laguesse S, Florido J, Houdeville M, Choquet A, Encislai B, Arena G, De Blasio C, Wendling O, Frenois FX, Papon L, Stuani L, Fuentes M, Jahannault Talignani C, Rousseau M, Guegan J, Buscail Y, Dupre P, Michaud HA, Rodier G, Bellvert F, Kulyk H, Ferraro Peyret C, Mathieu H, Close P, Rapino F, Chaveroux C, Pirot N, Rubio L, Torro A, Sorg T, Ango F, Hirtz C, Compan V, Lebigot E, Legati A, Ghezzi D, Nguyen L, David A, Sardet C, Lacroix M, Le Cam L, E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development. Nat Commun. 2025 Jan 2;16(1):67 |
Emc1 ER membrane protein complex subunit 1 (Synonyms: C230096C10Rik, mKIAA0090) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Emc3 ER membrane protein complex subunit 3 (Synonyms: 0610039A15Rik, Tmem111) | |
Results | Reference |
1* | J:332497 Tang X, Wei W, Snowball JM, Nakayasu ES, Bell SM, Ansong C, Lin X, Whitsett JA, EMC3 regulates mesenchymal cell survival via control of the mitotic spindle assembly. iScience. 2023 Jan 20;26(1):105667 |
Emc4 ER membrane protein complex subunit 4 (Synonyms: 2610318K02Rik, Tmem85) | |
Results | Reference |
1* | J:332497 Tang X, Wei W, Snowball JM, Nakayasu ES, Bell SM, Ansong C, Lin X, Whitsett JA, EMC3 regulates mesenchymal cell survival via control of the mitotic spindle assembly. iScience. 2023 Jan 20;26(1):105667 |
Emcn endomucin (Synonyms: 0610012K22Rik) | |
Results | Reference |
1 | J:263978 Ariza L, Canete A, Rojas A, Munoz-Chapuli R, Carmona R, Role of the Wilms' tumor suppressor gene Wt1 in pancreatic development. Dev Dyn. 2018 Apr 30; |
1 | J:237340 Ben Shoham A, Rot C, Stern T, Krief S, Akiva A, Dadosh T, Sabany H, Lu Y, Kadler KE, Zelzer E, Deposition of collagen type I onto skeletal endothelium reveals a new role for blood vessels in regulating bone morphology. Development. 2016 Nov 01;143(21):3933-3943 |
1 | J:269938 Bovay E, Sabine A, Prat-Luri B, Kim S, Son K, Willrodt AH, Olsson C, Halin C, Kiefer F, Betsholtz C, Jeon NL, Luther SA, Petrova TV, Multiple roles of lymphatic vessels in peripheral lymph node development. J Exp Med. 2018 Nov 5;215(11):2760-2777 |
1 | J:302542 Cahill TJ, Sun X, Ravaud C, Villa Del Campo C, Klaourakis K, Lupu IE, Lord AM, Browne C, Jacobsen SEW, Greaves DR, Jackson DG, Cowley SA, James W, Choudhury RP, Vieira JM, Riley PR, Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart. Development. 2021 Feb 3;148(3):dev194563 |
1 | J:254639 Chen L, Martino V, Dombkowski A, Williams T, West-Mays J, Gage PJ, AP-2beta Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development. Invest Ophthalmol Vis Sci. 2016 Mar;57(3):1072-81 |
1 | J:333725 Chiang IKN, Graus MS, Kirschnick N, Davidson T, Luu W, Harwood R, Jiang K, Li B, Wong YY, Moustaqil M, Lesieur E, Skoczylas R, Kouskoff V, Kazenwadel J, Arriola-Martinez L, Sierecki E, Gambin Y, Alitalo K, Kiefer F, Harvey NL, Francois M, The blood vasculature instructs lymphatic patterning in a SOX7-dependent manner. EMBO J. 2023 Mar 1;42(5):e109032 |
1 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1 | J:205408 Delalande JM, Natarajan D, Vernay B, Finlay M, Ruhrberg C, Thapar N, Burns AJ, Vascularisation is not necessary for gut colonisation by enteric neural crest cells. Dev Biol. 2014 Jan 15;385(2):220-9 |
1 | J:207561 Dellinger MT, Meadows SM, Wynne K, Cleaver O, Brekken RA, Vascular endothelial growth factor receptor-2 promotes the development of the lymphatic vasculature. PLoS One. 2013;8(9):e74686 |
1 | J:316977 Endale M, Ahlfeld S, Bao E, Chen X, Green J, Bess Z, Weirauch MT, Xu Y, Perl AK, Temporal, spatial, and phenotypical changes of PDGFRalpha expressing fibroblasts during late lung development. Dev Biol. 2017 May 15;425(2):161-175 |
1 | J:333567 Gonzalez-Meljem JM, Ivins S, Andoniadou CL, Le Tissier P, Scambler P, Martinez-Barbera JP, An expression and function analysis of the CXCR4/SDF-1 signalling axis during pituitary gland development. PLoS One. 2023;18(2):e0280001 |
1 | J:264149 Goto S, Onishi A, Misaki K, Yonemura S, Sugita S, Ito H, Ohigashi Y, Ema M, Sakaguchi H, Nishida K, Takahashi M, Neural retina-specific Aldh1a1 controls dorsal choroidal vascular development via Sox9 expression in retinal pigment epithelial cells. Elife. 2018 Apr 3;7:e32358 |
1 | J:239364 Ivins S, Chappell J, Vernay B, Suntharalingham J, Martineau A, Mohun TJ, Scambler PJ, The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development. Dev Cell. 2015 May 26;33(4):455-68 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:222246 Klotz L, Norman S, Vieira JM, Masters M, Rohling M, Dube KN, Bollini S, Matsuzaki F, Carr CA, Riley PR, Cardiac lymphatics are heterogeneous in origin and respond to injury. Nature. 2015 Jun 4;522(7554):62-7 |
1 | J:250555 Langen UH, Pitulescu ME, Kim JM, Enriquez-Gasca R, Sivaraj KK, Kusumbe AP, Singh A, Di Russo J, Bixel MG, Zhou B, Sorokin L, Vaquerizas JM, Adams RH, Cell-matrix signals specify bone endothelial cells during developmental osteogenesis. Nat Cell Biol. 2017 Mar;19(3):189-201 |
1* | J:331874 Lee H, Kim DW, Deletion of ATAD3A inhibits osteogenesis by impairing mitochondria structure and function in pre-osteoblast. Dev Dyn. 2022 Dec;251(12):1982-2000 |
1 | J:268341 Lee SY, Abel ED, Long F, Glucose metabolism induced by Bmp signaling is essential for murine skeletal development. Nat Commun. 2018 Nov 16;9(1):4831 |
1 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
1 | J:322701 Liu Y, Chen Q, Jeong HW, Koh BI, Watson EC, Xu C, Stehling M, Zhou B, Adams RH, A specialized bone marrow microenvironment for fetal haematopoiesis. Nat Commun. 2022 Mar 14;13(1):1327 |
1 | J:335167 Lu P, Wu B, Wang Y, Russell M, Liu Y, Bernard DJ, Zheng D, Zhou B, Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis. Dev Cell. 2023 Mar 29; |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1* | J:148803 McCulloch DR, Le Goff C, Bhatt S, Dixon LJ, Sandy JD, Apte SS, Adamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues. Gene Expr Patterns. 2009 Jun;9(5):314-23 |
2 | J:214759 McKenna CC, Ojeda AF, Spurlin J 3rd, Kwiatkowski S, Lwigale PY, Sema3A maintains corneal avascularity during development by inhibiting Vegf induced angioblast migration. Dev Biol. 2014 Jul 15;391(2):241-50 |
1 | J:211806 Outeda P, Huso DL, Fisher SA, Halushka MK, Kim H, Qian F, Germino GG, Watnick T, Polycystin signaling is required for directed endothelial cell migration and lymphatic development. Cell Rep. 2014 May 8;7(3):634-44 |
1 | J:286013 Outhwaite JE, Patel J, Simmons DG, Secondary Placental Defects in Cxadr Mutant Mice. Front Physiol. 2019;10:622 |
1 | J:264119 Pichol-Thievend C, Betterman KL, Liu X, Ma W, Skoczylas R, Lesieur E, Bos FL, Schulte D, Schulte-Merker S, Hogan BM, Oliver G, Harvey NL, Francois M, A blood capillary plexus-derived population of progenitor cells contributes to genesis of the dermal lymphatic vasculature during embryonic development. Development. 2018 May 17;145(10):dev160184 |
1 | J:235606 Ramo K, Sugamura K, Craige S, Keaney JF, Davis RJ, Suppression of ischemia in arterial occlusive disease by JNK-promoted native collateral artery development. Elife. 2016;5:e18414 |
1* | J:231047 Rios-Rojas C, Spiller C, Bowles J, Koopman P, Germ cells influence cord formation and leydig cell gene expression during mouse testis development. Dev Dyn. 2016 Apr;245(4):433-44 |
1 | J:296443 Rondon-Galeano M, Skoczylas R, Bower NI, Simons C, Gordon E, Francois M, Koltowska K, Hogan BM, MAFB modulates the maturation of lymphatic vascular networks in mice. Dev Dyn. 2020 Oct;249(10):1201-1216 |
1 | J:338019 Shi W, Scialdone AP, Emerson JI, Mei L, Wasson LK, Davies HA, Seidman CE, Seidman JG, Cook JG, Conlon FL, Missense Mutation in Human CHD4 Causes Ventricular Noncompaction by Repressing ADAMTS1. Circ Res. 2023 Jun 23;133(1):48-67 |
1 | J:338889 Siguero-Alvarez M, Salguero-Jimenez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sanchez-Saez F, Pineiro-Sabaris R, Felipe-Medina N, Torroja C, Gomez MJ, Sabater-Molina M, Escriba R, Richaud-Patin I, Iglesias-Garcia O, Sbroggio M, Callejas S, O'Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibanez B, Monserrat L, Perez-Pomares JM, Sanchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL, A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation. 2023 Jan 3;147(1):47-65 |
1 | J:363523 Sun X, Malandraki-Miller S, Kennedy T, Bassat E, Klaourakis K, Zhao J, Gamen E, Vieira JM, Tzahor E, Riley PR, The extracellular matrix protein agrin is essential for epicardial epithelial-to-mesenchymal transition during heart development. Development. 2021 May 1;148(9) |
1 | J:326699 Tosun B, Wolff LI, Houben A, Nutt S, Hartmann C, Osteoclasts and Macrophages-Their Role in Bone Marrow Cavity Formation During Mouse Embryonic Development. J Bone Miner Res. 2022 Jun 11; |
1 | J:299728 Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL, Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. Elife. 2019 Dec 4;8:e49977 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:361729 Yang G, He Q, Guo X, Li RY, Lin J, Lang Y, Tao W, Liu W, Lin H, Xing S, Qi Y, Xie Z, Han JJ, Zhou B, Teng Y, Yang X, Identification of the metaphyseal skeletal stem cell building trabecular bone. Sci Adv. 2024 Feb 23;10(8):eadl2238 |
1 | J:261328 Zou J, Ma W, Li J, Littlejohn R, Zhou H, Kim IM, Fulton DJR, Chen W, Weintraub NL, Zhou J, Su H, Neddylation mediates ventricular chamber maturation through repression of Hippo signaling. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4101-E4110 |
Emd emerin | |
Results | Reference |
1 | J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088 |
Emg1 EMG1 N1-specific pseudouridine methyltransferase (Synonyms: Grcc2f) | |
Results | Reference |
1* | J:230556 Armistead J, Patel N, Wu X, Hemming R, Chowdhury B, Basra GS, Del Bigio MR, Ding H, Triggs-Raine B, Growth arrest in the ribosomopathy, Bowen-Conradi syndrome, is due to dramatically reduced cell proliferation and a defect in mitotic progression. Biochim Biophys Acta. 2015 May;1852(5):1029-37 |
Emilin1 elastin microfibril interfacer 1 (Synonyms: 5830419M17Rik, EMILIN-1, gp115) | |
Results | Reference |
2* | J:81597 Braghetta P, Ferrari A, de Gemmis P, Zanetti M, Volpin D, Bonaldo P, Bressan GM, Expression of the EMILIN-1 gene during mouse development. Matrix Biol. 2002 Nov;21(7):603-9 |
1 | J:206101 Danussi C, Del Bel Belluz L, Pivetta E, Modica TM, Muro A, Wassermann B, Doliana R, Sabatelli P, Colombatti A, Spessotto P, EMILIN1/alpha9beta1 integrin interaction is crucial in lymphatic valve formation and maintenance. Mol Cell Biol. 2013 Nov;33(22):4381-94 |
Emilin2 elastin microfibril interfacer 2 (Synonyms: basilin, FOAP-10) | |
Results | Reference |
2* | J:88794 Braghetta P, Ferrari A, De Gemmis P, Zanetti M, Volpin D, Bonaldo P, Bressan GM, Overlapping, complementary and site-specific expression pattern of genes of the EMILIN/Multimerin family. Matrix Biol. 2004 Jan;22(7):549-56 |
Emilin3 elastin microfibril interfacer 3 (Synonyms: 1110013O17Rik, Emilin5, EMILIN-T) | |
Results | Reference |
1* | J:316162 Schiavinato A, Becker AK, Zanetti M, Corallo D, Milanetto M, Bizzotto D, Bressan G, Guljelmovic M, Paulsson M, Wagener R, Braghetta P, Bonaldo P, EMILIN-3, peculiar member of elastin microfibril interface-located protein (EMILIN) family, has distinct expression pattern, forms oligomeric assemblies, and serves as transforming growth factor beta (TGF-beta) antagonist. J Biol Chem. 2012 Mar 30;287(14):11498-515 |
Emp1 epithelial membrane protein 1 | |
Results | Reference |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
Emp2 epithelial membrane protein 2 (Synonyms: Xmp) | |
Results | Reference |
1 | J:243365 Williams CJ, Chu A, Jefferson WN, Casero D, Sudhakar D, Khurana N, Hogue CP, Aryasomayajula C, Patel P, Sullivan P, Padilla-Banks E, Mohandessi S, Janzen C, Wadehra M, Epithelial membrane protein 2 (EMP2) deficiency alters placental angiogenesis, mimicking features of human placental insufficiency. J Pathol. 2017 Jun;242(2):246-259 |
Emx1 empty spiracles homeobox 1 | |
Results | Reference |
1 | J:183848 Benadiba C, Magnani D, Niquille M, Morle L, Valloton D, Nawabi H, Ait-Lounis A, Otsmane B, Reith W, Theil T, Hornung JP, Lebrand C, Durand B, The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development. PLoS Genet. 2012 Mar;8(3):e1002606 |
1* | J:34633 Briata P, Di Blas E, Gulisano M, Mallamaci A, Iannone R, Boncinelli E, Corte G, EMX1 homeoprotein is expressed in cell nuclei of the developing cerebral cortex and in the axons of the olfactory sensory neurons. Mech Dev. 1996 Jul;57(2):169-80 |
1 | J:63713 Cecchi C, Boncinelli E, Emx homeogenes and mouse brain development. Trends Neurosci. 2000 Aug;23(8):347-52 |
1 | J:83383 Levi G, Puche AC, Mantero S, Barbieri O, Trombino S, Paleari L, Egeo A, Merlo GR, The Dlx5 homeodomain gene is essential for olfactory development and connectivity in the mouse. Mol Cell Neurosci. 2003 Apr;22(4):530-43 |
1* | J:226755 Lim JW, Donahoo AL, Bunt J, Edwards TJ, Fenlon LR, Liu Y, Zhou J, Moldrich RX, Piper M, Gobius I, Bailey TL, Wray NR, Kessaris N, Poo MM, Rubenstein JL, Richards LJ, EMX1 regulates NRP1-mediated wiring of the mouse anterior cingulate cortex. Development. 2015 Nov 1;142(21):3746-57 |
1 | J:196051 Moldrich RX, Gobius I, Pollak T, Zhang J, Ren T, Brown L, Mori S, De Juan Romero C, Britanova O, Tarabykin V, Richards LJ, Molecular regulation of the developing commissural plate. J Comp Neurol. 2010 Sep 15;518(18):3645-61 |
1* | J:38397 Yoshida M, Suda Y, Matsuo I, Miyamoto N, Takeda N, Kuratani S, Aizawa S, Emx1 and Emx2 functions in development of dorsal telencephalon. Development. 1997 Jan;124(1):101-11 |
Emx2 empty spiracles homeobox 2 (Synonyms: Pdo) | |
Results | Reference |
1 | J:355647 Bugacov H, Der B, Briantseva BM, Guo Q, Kim S, Lindstrom NO, McMahon AP, Dose-dependent responses to canonical Wnt transcriptional complexes in the regulation of mammalian nephron progenitors. Development. 2024 Sep 15;151(18) |
1 | J:63713 Cecchi C, Boncinelli E, Emx homeogenes and mouse brain development. Trends Neurosci. 2000 Aug;23(8):347-52 |
1 | J:218288 Falcone C, Filippis C, Granzotto M, Mallamaci A, Emx2 expression levels in NSCs modulate astrogenesis rates by regulating EgfR and Fgf9. Glia. 2015 Mar;63(3):412-22 |
1 | J:314124 Gao Y, Duque-Wilckens N, Aljazi MB, Wu Y, Moeser AJ, Mias GI, Robison AJ, He J, Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors. Commun Biol. 2021 Jun 18;4(1):756 |
1 | J:330450 Ji YR, Tona Y, Wafa T, Christman ME, Tourney ED, Jiang T, Ohta S, Cheng H, Fitzgerald T, Fritzsch B, Jones SM, Cullen KE, Wu DK, Function of bidirectional sensitivity in the otolith organs established by transcription factor Emx2. Nat Commun. 2022 Oct 24;13(1):6330 |
1* | J:78716 Lopez-Bendito G, Chan CH, Mallamaci A, Parnavelas J, Molnar Z, Role of Emx2 in the development of the reciprocal connectivity between cortex and thalamus. J Comp Neurol. 2002 Sep 16;451(2):153-69 |
1* | J:221341 Lun MP, Johnson MB, Broadbelt KG, Watanabe M, Kang YJ, Chau KF, Springel MW, Malesz A, Sousa AM, Pletikos M, Adelita T, Calicchio ML, Zhang Y, Holtzman MJ, Lidov HG, Sestan N, Steen H, Monuki ES, Lehtinen MK, Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production. J Neurosci. 2015 Mar 25;35(12):4903-16 |
1* | J:51432 Mallamaci A, Iannone R, Briata P, Pintonello L, Mercurio S, Boncinelli E, Corte G, EMX2 protein in the developing mouse brain and olfactory area. Mech Dev. 1998 Oct;77(2):165-72 |
1* | J:40605 Miyamoto N, Yoshida M, Kuratani S, Matsuo I, Aizawa S, Defects of urogenital development in mice lacking Emx2. Development. 1997 May;124(9):1653-64 |
1 | J:89093 Rhodes CR, Parkinson N, Tsai H, Brooker D, Mansell S, Spurr N, Hunter AJ, Steel KP, Brown SD, The homeobox gene Emx2 underlies middle ear and inner ear defects in the deaf mouse mutant pardon. J Neurocytol. 2003 Nov;32(9):1143-54 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:98620 Tole S, Remedios R, Saha B, Stoykova A, Selective requirement of Pax6, but not Emx2, in the specification and development of several nuclei of the amygdaloid complex. J Neurosci. 2005 Mar 9;25(10):2753-60 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
1* | J:38397 Yoshida M, Suda Y, Matsuo I, Miyamoto N, Takeda N, Kuratani S, Aizawa S, Emx1 and Emx2 functions in development of dorsal telencephalon. Development. 1997 Jan;124(1):101-11 |
2 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
En1 engrailed 1 (Synonyms: En-1, engrailed-1, Mo-en.1) | |
Results | Reference |
1 | J:119323 Atit R, Sgaier SK, Mohamed OA, Taketo MM, Dufort D, Joyner AL, Niswander L, Conlon RA, Beta-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse. Dev Biol. 2006 Aug 1;296(1):164-76 |
1* | J:31313 Davis CA, Joyner AL, Expression patterns of the homeo box-containing genes En-1 and En-2 and the proto-oncogene int-1 diverge during mouse development. Genes Dev. 1988 Dec;2(12B):1736-44 |
2 | J:358820 Dudukcu O, Raj DDA, van de Haar LL, Grossouw LM, Linders LE, Garritsen O, Adolfs Y, van Kronenburg NCH, Broekhoven MH, Kapteijns THW, Meye FJ, Pasterkamp RJ, Molecular diversity and migration of GABAergic neurons in the developing ventral midbrain. iScience. 2024 Nov 15;27(11):111239 |
1* | J:331872 Johnson GL, Glasser MB, Charles JF, Duryea J, Lehoczky JA, En1 and Lmx1b do not recapitulate embryonic dorsal-ventral limb patterning functions during mouse digit tip regeneration. Cell Rep. 2022 Nov 22;41(8):111701 |
1* | J:8126 Joyner AL, Kornberg T, Coleman KG, Cox DR, Martin GR, Expression during embryogenesis of a mouse gene with sequence homology to the Drosophila engrailed gene. Cell. 1985 Nov;43(1):29-37 |
1* | J:9012 Joyner AL, Martin GR, En-1 and En-2, two mouse genes with sequence homology to the Drosophila engrailed gene: expression during embryogenesis [published erratum appears in Genes Dev 1987 Jul;1(5):521]. Genes Dev. 1987 Mar;1(1):29-38 |
1* | J:199186 Juuri E, Saito K, Lefebvre S, Michon F, Establishment of crown-root domain borders in mouse incisor. Gene Expr Patterns. 2013 Oct;13(7):255-64 |
1 | J:70191 Pierani A, Moran-Rivard L, Sunshine MJ, Littman DR, Goulding M, Jessell TM, Control of interneuron fate in the developing spinal cord by the progenitor homeodomain protein Dbx1. Neuron. 2001 Feb;29(2):367-84 |
1* | J:336866 Puelles L, Hidalgo-Sanchez M, The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer. Int J Mol Sci. 2023 Jun 5;24(11) |
1* | J:161576 Zhong SC, Chen XS, Cai QY, Luo X, Chen XH, Liu J, Yao ZX, Dynamic expression and heterogeneous intracellular location of En-1 during late mouse embryonic development. Cells Tissues Organs. 2010;191(4):289-300 |
En2 engrailed 2 (Synonyms: En-2) | |
Results | Reference |
1* | J:9012 Joyner AL, Martin GR, En-1 and En-2, two mouse genes with sequence homology to the Drosophila engrailed gene: expression during embryogenesis [published erratum appears in Genes Dev 1987 Jul;1(5):521]. Genes Dev. 1987 Mar;1(1):29-38 |
Enah ENAH actin regulator (Synonyms: Mena, Ndpp1) | |
Results | Reference |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
Enam enamelin (Synonyms: abte) | |
Results | Reference |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
2 | J:188148 Landin MA, Shabestari M, Babaie E, Reseland JE, Osmundsen H, Gene Expression Profiling during Murine Tooth Development. Front Genet. 2012;3:139 |
Enc1 ectodermal-neural cortex 1 (Synonyms: Nrpb, PIG10) | |
Results | Reference |
1 | J:39574 Hernandez MC, Andres-Barquin PJ, Martinez S, Bulfone A, Rubenstein JL , Israel MA, ENC-1: a novel mammalian kelch-related gene specifically expressed in the nervous system encodes an actin-binding protein. J Neurosci. 1997 May 1;17(9):3038-51 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Eng endoglin (Synonyms: CD105, Endo) | |
Results | Reference |
1 | J:231798 Chen CY, Chan CH, Chen CM, Tsai YS, Tsai TY, Wu Lee YH, You LR, Targeted inactivation of murine Ddx3x: essential roles of Ddx3x in placentation and embryogenesis. Hum Mol Genet. 2016 July 15;25(14):2905-2922 |
1 | J:308976 He DD, Tang XT, Dong W, Cui G, Peng G, Yin X, Chen Y, Jing N, Zhou BO, C-KIT Expression Distinguishes Fetal from Postnatal Skeletal Progenitors. Stem Cell Reports. 2020 Apr 14;14(4):614-630 |
Eno1 enolase 1, alpha non-neuron (Synonyms: 2-phospho-D-glycerate hydrolase, alpha-enolase, c-Myc promoter binding protein, Eno-1, MBP-1) | |
Results | Reference |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
Eno2 enolase 2, gamma neuronal (Synonyms: D6Ertd375e, Eno-2, NSE) | |
Results | Reference |
1 | J:44100 Rich KA, Zhan Y, Blanks JC, Migration and synaptogenesis of cone photoreceptors in the developing mouse retina. J Comp Neurol. 1997 Nov 10;388(1):47-63 |
1 | J:64148 Vannucchi MG, Faussone-Pellegrini MS, Synapse formation during neuron differentiation: An in situ study of the myenteric plexus during murine embryonic life. J Comp Neurol. 2000 Sep 25;425(3):369-81 |
1* | J:36520 Wakisaka S, Miyawaki Y, Youn SH, Kato J, Kurisu K, Protein gene-product 9.5 in developing mouse circumvallate papilla: comparison with neuron-specific enolase and calcitonin gene-related peptide. Anat Embryol (Berl). 1996 Oct;194(4):365-72 |
Eno3 enolase 3, beta muscle (Synonyms: Eno-3) | |
Results | Reference |
1 | J:160383 Messina G, Biressi S, Monteverde S, Magli A, Cassano M, Perani L, Roncaglia E, Tagliafico E, Starnes L, Campbell CE, Grossi M, Goldhamer DJ, Gronostajski RM, Cossu G, Nfix regulates fetal-specific transcription in developing skeletal muscle. Cell. 2010 Feb 19;140(4):554-66 |
1 | J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97 |
Enpp1 ectonucleotide pyrophosphatase/phosphodiesterase 1 (Synonyms: 4833416E15Rik, CD203c, E-NPP1, Ly-41, NPP1, Npps, PC-1, Pca, Pca-1, Pdnp1, twy) | |
Results | Reference |
1 | J:276880 Motch Perrine SM, Wu M, Stephens NB, Kriti D, van Bakel H, Jabs EW, Richtsmeier JT, Mandibular dysmorphology due to abnormal embryonic osteogenesis in FGFR2-related craniosynostosis mice. Dis Model Mech. 2019 May 30;12(5):dmm038513 |
Enpp2 ectonucleotide pyrophosphatase/phosphodiesterase 2 (Synonyms: ATX, Autotaxin, Npps2, PD-Ialpha, Pdnp2) | |
Results | Reference |
1 | J:226941 Akerberg BN, Sarangam ML, Stankunas K, Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Dev Biol. 2015 Nov 1;407(1):158-72 |
1* | J:56413 Bachner D, Ahrens M, Betat N, Schroder D, Gross G, Developmental expression analysis of murine autotaxin (ATX). Mech Dev. 1999 Jun;84(1-2):121-5 |
1* | J:51222 Bachner D, Ahrens M, Schroder D, Hoffmann A, Lauber J, Betat N, Steinert P, Flohe L, Gross G, Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T1/2). Dev Dyn. 1998 Dec;213(4):398-411 |
Entpd4 ectonucleoside triphosphate diphosphohydrolase 4 (Synonyms: 1200014F22Rik, A430102M06Rik, Lysal1, mKIAA0392) | |
Results | Reference |
1* | J:129949 Cui CY, Kunisada M, Esibizione D, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet. 2007 Nov 1;16(21):2583-90 |
Eomes eomesodermin (Synonyms: Tbr2) | |
Results | Reference |
1 | J:225279 Arno B, Grassivaro F, Rossi C, Bergamaschi A, Castiglioni V, Furlan R, Greter M, Favaro R, Comi G, Becher B, Martino G, Muzio L, Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex. Nat Commun. 2014;5:5611 |
1 | J:299451 Atkins A, Xu MJ, Li M, Rogers NP, Pryzhkova MV, Jordan PW, SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. Elife. 2020 Nov 17;9:e61171 |
1 | J:305458 Bertacchi M, Romano AL, Loubat A, Tran Mau-Them F, Willems M, Faivre L, Khau van Kien P, Perrin L, Devillard F, Sorlin A, Kuentz P, Philippe C, Garde A, Neri F, Di Giaimo R, Oliviero S, Cappello S, D'Incerti L, Frassoni C, Studer M, NR2F1 regulates regional progenitor dynamics in the mouse neocortex and cortical gyrification in BBSOAS patients. EMBO J. 2020 Jul 1;39(13):e104163 |
1 | J:356256 Bertino F, Mukherjee D, Bonora M, Bagowski C, Nardelli J, Metani L, Zanin Venturini DI, Chianese D, Santander N, Salaroglio IC, Hentschel A, Quarta E, Genova T, McKinney AA, Allocco AL, Fiorito V, Petrillo S, Ammirata G, De Giorgio F, Dennis E, Allington G, Maier F, Shoukier M, Gloning KP, Munaron L, Mussano F, Salsano E, Pareyson D, di Rocco M, Altruda F, Panagiotakos G, Kahle KT, Gressens P, Riganti C, Pinton PP, Roos A, Arnold T, Tolosano E, Chiabrando D, Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus. Cell Rep Med. 2024 Jul 16;5(7):101647 |
1 | J:203970 Betancourt J, Katzman S, Chen B, Nuclear factor one B regulates neural stem cell differentiation and axonal projection of corticofugal neurons. J Comp Neurol. 2014 Jan 1;522(1):6-35 |
1 | J:278765 Bittermann E, Abdelhamed Z, Liegel RP, Menke C, Timms A, Beier DR, Stottmann RW, Differential requirements of tubulin genes in mammalian forebrain development. PLoS Genet. 2019 Aug;15(8):e1008243 |
1 | J:316182 Blume M, Inoguchi F, Sugiyama T, Owada Y, Osumi N, Aimi Y, Taki K, Katsuyama Y, Dab1 contributes differently to the morphogenesis of the hippocampal subdivisions. Dev Growth Differ. 2017 Oct;59(8):657-673 |
1 | J:234630 Bonney S, Harrison-Uy S, Mishra S, MacPherson AM, Choe Y, Li D, Jaminet SC, Fruttiger M, Pleasure SJ, Siegenthaler JA, Diverse Functions of Retinoic Acid in Brain Vascular Development. J Neurosci. 2016 Jul 20;36(29):7786-801 |
1* | J:55094 Bulfone A, Martinez S, Marigo V, Campanella M, Basile A, Quaderi N, Gattuso C, Rubenstein JL, Ballabio A, Expression pattern of the Tbr2 (Eomesodermin) gene during mouse and chick brain development. Mech Dev. 1999 Jun;84(1-2):133-8 |
1 | J:353339 Butts JC, Wu SR, Durham MA, Dhindsa RS, Revelli JP, Ljungberg MC, Saulnier O, McLaren ME, Taylor MD, Zoghbi HY, A single-cell transcriptomic map of the developing Atoh1 lineage identifies neural fate decisions and neuronal diversity in the hindbrain. Dev Cell. 2024 Aug 19;59(16):2171-2188.e7 |
1 | J:182669 Cappello S, Bohringer CR, Bergami M, Conzelmann KK, Ghanem A, Tomassy GS, Arlotta P, Mainardi M, Allegra M, Caleo M, van Hengel J, Brakebusch C, Gotz M, A radial glia-specific role of RhoA in double cortex formation. Neuron. 2012 Mar 8;73(5):911-24 |
1 | J:264379 Cardenas A, Villalba A, de Juan Romero C, Pico E, Kyrousi C, Tzika AC, Tessier-Lavigne M, Ma L, Drukker M, Cappello S, Borrell V, Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels. Cell. 2018 Jul 26;174(3):590-606.e21 |
1 | J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5 |
1* | J:318768 Carpentieri JA, Di Cicco A, Lampic M, Andreau D, Del Maestro L, El Marjou F, Coquand L, Bahi-Buisson N, Brault JB, Baffet AD, Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly. Nat Commun. 2022 Jan 10;13(1):16 |
1 | J:300487 Chai G, Webb A, Li C, Antaki D, Lee S, Breuss MW, Lang N, Stanley V, Anzenberg P, Yang X, Marshall T, Gaffney P, Wierenga KJ, Chung BH, Tsang MH, Pais LS, Lovgren AK, VanNoy GE, Rehm HL, Mirzaa G, Leon E, Diaz J, Neumann A, Kalverda AP, Manfield IW, Parry DA, Logan CV, Johnson CA, Bonthron DT, Valleley EMA, Issa MY, Abdel-Ghafar SF, Abdel-Hamid MS, Jennings P, Zaki MS, Sheridan E, Gleeson JG, Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 Jan 20;109(2):241-256.e9 |
1 | J:127045 Chakrabarti L, Galdzicki Z, Haydar TF, Defects in embryonic neurogenesis and initial synapse formation in the forebrain of the Ts65Dn mouse model of Down syndrome. J Neurosci. 2007 Oct 24;27(43):11483-95 |
1 | J:282264 Chen P, Zhang T, Yuan Z, Shen B, Chen L, Expression of the RNA methyltransferase Nsun5 is essential for developing cerebral cortex. Mol Brain. 2019 Aug 28;12(1):74 |
1 | J:346633 Cheng J, Wang Z, Tang M, Zhang W, Li G, Tan S, Mu C, Hu M, Zhang D, Jia X, Wen Y, Guo H, Xu D, Liu L, Li J, Xia K, Li F, Duan R, Xu Z, Yuan L, KCTD10 regulates brain development by destabilizing brain disorder-associated protein KCTD13. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2315707121 |
1 | J:158610 Coffinier C, Chang SY, Nobumori C, Tu Y, Farber EA, Toth JI, Fong LG, Young SG, Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5076-81 |
1 | J:346120 Cornejo F, Franchini N, Cortes BI, Elgueta D, Cancino GI, Neural conditional ablation of the protein tyrosine phosphatase receptor Delta PTPRD impairs gliogenesis in the developing mouse brain cortex. Front Cell Dev Biol. 2024;12:1357862 |
1 | J:235557 Diaz-Alonso J, Aguado T, de Salas-Quiroga A, Ortega Z, Guzman M, Galve-Roperh I, CB1 Cannabinoid Receptor-Dependent Activation of mTORC1/Pax6 Signaling Drives Tbr2 Expression and Basal Progenitor Expansion in the Developing Mouse Cortex. Cereb Cortex. 2015 Sep;25(9):2395-408 |
1 | J:198427 Dudok JJ, Sanz AS, Lundvig DM, Wijnholds J, MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. J Neurosci. 2013 May 8;33(19):8518-27 |
1 | J:180242 Dupressoir A, Vernochet C, Harper F, Guegan J, Dessen P, Pierron G, Heidmann T, A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1164-73 |
1 | J:95876 Englund C, Fink A, Lau C, Pham D, Daza RA, Bulfone A, Kowalczyk T, Hevner RF, Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex. J Neurosci. 2005 Jan 5;25(1):247-51 |
1 | J:112207 Englund C, Kowalczyk T, Daza RA, Dagan A, Lau C, Rose MF, Hevner RF, Unipolar brush cells of the cerebellum are produced in the rhombic lip and migrate through developing white matter. J Neurosci. 2006 Sep 6;26(36):9184-95 |
1* | J:78160 Faedo A, Ficara F, Ghiani M, Aiuti A, Rubenstein JL, Bulfone A, Developmental expression of the T-box transcription factor T-bet/Tbx21 during mouse embryogenesis. Mech Dev. 2002 Aug;116(1-2):157-60 |
1 | J:144651 Farkas LM, Haffner C, Giger T, Khaitovich P, Nowick K, Birchmeier C, Paabo S, Huttner WB, Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex. Neuron. 2008 Oct 9;60(1):40-55 |
1 | J:211816 Fei JF, Haffner C, Huttner WB, 3' UTR-dependent, miR-92-mediated restriction of Tis21 expression maintains asymmetric neural stem cell division to ensure proper neocortex size. Cell Rep. 2014 Apr 24;7(2):398-411 |
1 | J:250440 Ferguson R, Serafeimidou-Pouliou E, Subramanian V, Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation. J Anat. 2016 Dec;229(6):871-891 |
1 | J:106708 Fink AJ, Englund C, Daza RA, Pham D, Lau C, Nivison M, Kowalczyk T, Hevner RF, Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip. J Neurosci. 2006 Mar 15;26(11):3066-76 |
1 | J:269420 Franz H, Villarreal A, Heidrich S, Videm P, Kilpert F, Mestres I, Calegari F, Backofen R, Manke T, Vogel T, DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex. Nucleic Acids Res. 2019 Jan 10;47(1):168-183 |
1 | J:229060 Franzoni E, Booker SA, Parthasarathy S, Rehfeld F, Grosser S, Srivatsa S, Fuchs HR, Tarabykin V, Vida I, Wulczyn FG, miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6. Elife. 2015;4 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:206763 Gan Q, Lee A, Suzuki R, Yamagami T, Stokes A, Nguyen BC, Pleasure D, Wang J, Chen HW, Zhou CJ, Pax6 mediates ss-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells. Stem Cells. 2014 Jan;32(1):45-58 |
2 | J:217584 Gerstmann K, Pensold D, Symmank J, Khundadze M, Hubner CA, Bolz J, Zimmer G, Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions. Development. 2015 Jan 1;142(1):140-50 |
1 | J:215584 Gil-Sanz C, Landeira B, Ramos C, Costa MR, Muller U, Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon. J Neurosci. 2014 Aug 6;34(32):10475-87 |
1 | J:286645 Gilet JG, Ivanova EL, Trofimova D, Rudolf G, Meziane H, Broix L, Drouot N, Courraud J, Skory V, Voulleminot P, Osipenko M, Bahi-Buisson N, Yalcin B, Birling MC, Hinckelmann MV, Kwok BH, Allingham JS, Chelly J, Conditional switching of KIF2A mutation provides new insights into cortical malformation pathogeny. Hum Mol Genet. 2020 Mar 27;29(5):766-784 |
1 | J:151321 Glickstein SB, Monaghan JA, Koeller HB, Jones TK, Ross ME, Cyclin D2 is critical for intermediate progenitor cell proliferation in the embryonic cortex. J Neurosci. 2009 Jul 29;29(30):9614-24 |
1 | J:231665 Goodliffe JW, Olmos-Serrano JL, Aziz NM, Pennings JL, Guedj F, Bianchi DW, Haydar TF, Absence of Prenatal Forebrain Defects in the Dp(16)1Yey/+ Mouse Model of Down Syndrome. J Neurosci. 2016 Mar 9;36(10):2926-44 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
1 | J:176240 Hand R, Polleux F, Neurogenin2 regulates the initial axon guidance of cortical pyramidal neurons projecting medially to the corpus callosum. Neural Dev. 2011;6:30 |
1 | J:287499 Hattori Y, Naito Y, Tsugawa Y, Nonaka S, Wake H, Nagasawa T, Kawaguchi A, Miyata T, Transient microglial absence assists postmigratory cortical neurons in proper differentiation. Nat Commun. 2020 Apr 2;11(1):1631 |
1 | J:340417 Hendrikse LD, Haldipur P, Saulnier O, Millman J, Sjoboen AH, Erickson AW, Ong W, Gordon V, Coudiere-Morrison L, Mercier AL, Shokouhian M, Suarez RA, Ly M, Borlase S, Scott DS, Vladoiu MC, Farooq H, Sirbu O, Nakashima T, Nambu S, Funakoshi Y, Bahcheli A, Diaz-Mejia JJ, Golser J, Bach K, Phuong-Bao T, Skowron P, Wang EY, Kumar SA, Balin P, Visvanathan A, Lee JJY, Ayoub R, Chen X, Chen X, Mungall KL, Luu B, Berube P, Wang YC, Pfister SM, Kim SK, Delattre O, Bourdeaut F, Doz F, Masliah-Planchon J, Grajkowska WA, Loukides J, Dirks P, Fevre-Montange M, Jouvet A, French PJ, Kros JM, Zitterbart K, Bailey SD, Eberhart CG, Rao AAN, Giannini C, Olson JM, Garami M, Hauser P, Phillips JJ, Ra YS, de Torres C, Mora J, Li KKW, Ng HK, Poon WS, Pollack IF, Lopez-Aguilar E, Gillespie GY, Van Meter TE, Shofuda T, Vibhakar R, Thompson RC, Cooper MK, Rubin JB, Kumabe T, Jung S, Lach B, Iolascon A, Ferrucci V, de Antonellis P, Zollo M, Cinalli G, Robinson S, Stearns DS, Van Meir EG, Porrati P, Finocchiaro G, Massimino M, Carlotti CG, Faria CC, Roussel MF, Boop F, Chan JA, Aldinger KA, Razavi F, Silvestri E, McLendon RE, Thompson EM, Ansari M, Garre ML, Chico F, Eguia P, Perezpena M, Morrissy AS, Cavalli FMG, Wu X, Daniels C, Rich JN, Jones SJM, Moore RA, Marra MA, Huang X, Reimand J, Sorensen PH, Wechsler-Reya RJ, Weiss WA, Pugh TJ, Garzia L, Kleinman CL, Stein LD, Jabado N, Malkin D, Ayrault O, Golden JA, Ellison DW, Doble B, Ramaswamy V, Werbowetski-Ogilvie TE, Suzuki H, Millen KJ, Taylor MD, Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. 2022 Sep;609(7929):1021-1028 |
1 | J:196059 Hodge RD, Garcia AJ 3rd, Elsen GE, Nelson BR, Mussar KE, Reiner SL, Ramirez JM, Hevner RF, Tbr2 expression in Cajal-Retzius cells and intermediate neuronal progenitors is required for morphogenesis of the dentate gyrus. J Neurosci. 2013 Feb 27;33(9):4165-80 |
1 | J:238096 Houlihan SL, Lanctot AA, Guo Y, Feng Y, Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis. Elife. 2016 Sep 24;5:e17823 |
1 | J:253242 Hu XL, Chen G, Zhang S, Zheng J, Wu J, Bai QR, Wang Y, Li J, Wang H, Feng H, Li J, Sun X, Xia Q, Yang F, Hang J, Qi C, Phoenix TN, Temple S, Shen Q, Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells. Neuron. 2017 Jul 19;95(2):309-325.e6 |
1* | J:171479 Hutton SR, Pevny LH, SOX2 expression levels distinguish between neural progenitor populations of the developing dorsal telencephalon. Dev Biol. 2011 Apr 1;352(1):40-7 |
1 | J:217499 Iwashita M, Kataoka N, Toida K, Kosodo Y, Systematic profiling of spatiotemporal tissue and cellular stiffness in the developing brain. Development. 2014 Oct;141(19):3793-8 |
1 | J:205043 Janisch KM, Vock VM, Fleming MS, Shrestha A, Grimsley-Myers CM, Rasoul BA, Neale SA, Cupp TD, Kinchen JM, Liem KF Jr, Dwyer ND, The vertebrate-specific Kinesin-6, Kif20b, is required for normal cytokinesis of polarized cortical stem cells and cerebral cortex size. Development. 2013 Dec;140(23):4672-82 |
1 | J:334107 Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J, Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice. Hum Mol Genet. 2022 Oct 10;31(20):3504-3520 |
1 | J:249035 Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M, McGillewie L, Bar S, Minocha S, Chevalier C, Po C, Chelly J, Mandel JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, Herault Y, Collins SC, Friant S, Godin JD, Yalcin B, WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9308-E9317 |
1* | J:347773 Kim HY, Kang B, Lee PR, Kim K, Hong GS, Expression patterns of Piezo1 in the developing mouse forebrain. Brain Struct Funct. 2024 Apr;229(3):759-773 |
1 | J:222255 Knock E, Pereira J, Lombard PD, Dimond A, Leaford D, Livesey FJ, Hendrich B, The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex. Neural Dev. 2015;10:13 |
1 | J:201110 Komada M, Iguchi T, Takeda T, Ishibashi M, Sato M, Smoothened controls cyclin D2 expression and regulates the generation of intermediate progenitors in the developing cortex. Neurosci Lett. 2013 Jun 28;547:87-91 |
1* | J:163966 Kowalczyk T, Pontious A, Englund C, Daza RA, Bedogni F, Hodge R, Attardo A, Bell C, Huttner WB, Hevner RF, Intermediate neuronal progenitors (basal progenitors) produce pyramidal-projection neurons for all layers of cerebral cortex. Cereb Cortex. 2009 Oct;19(10):2439-50 |
1 | J:343097 Kurabayashi N, Fujii K, Otobe Y, Hiroki S, Hiratsuka M, Yoshitane H, Kazuki Y, Takao K, Neocortical neuronal production and maturation defects in the TcMAC21 mouse model of Down syndrome. iScience. 2023 Dec 15;26(12):108379 |
1 | J:158681 Kuwahara A, Hirabayashi Y, Knoepfler PS, Taketo MM, Sakai J, Kodama T, Gotoh Y, Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex. Development. 2010 Apr;137(7):1035-44 |
1 | J:254235 Lanctot AA, Guo Y, Le Y, Edens BM, Nowakowski RS, Feng Y, Loss of Brap Results in Premature G1/S Phase Transition and Impeded Neural Progenitor Differentiation. Cell Rep. 2017 Aug 1;20(5):1148-1160 |
1 | J:317151 Lavado A, Gangwar R, Pare J, Wan S, Fan Y, Cao X, YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development. Dev Biol. 2021 Dec;480:39-49 |
1 | J:261049 Leone DP, Srinivasan K, Brakebusch C, McConnell SK, The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain. Dev Neurobiol. 2010 Aug;70(9):659-78 |
1 | J:306873 Li L, Jin J, Yang XJ, Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells. iScience. 2019 Oct 25;20:148-167 |
2* | J:294282 Li L, Ruan X, Wen C, Chen P, Liu W, Zhu L, Xiang P, Zhang X, Wei Q, Hou L, Yin B, Yuan J, Qiang B, Shu P, Peng X, The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019 Jul 16;28(3):698-711.e5 |
1* | J:297829 Li W, Shen W, Zhang B, Tian K, Li Y, Mu L, Luo Z, Zhong X, Wu X, Liu Y, Zhou Y, Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b. Protein Cell. 2020 Mar;11(3):161-186 |
2* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1 | J:348287 Liang XG, Hoang K, Meyerink BL, Kc P, Paraiso K, Wang L, Jones IR, Zhang Y, Katzman S, Finn TS, Tsyporin J, Qu F, Chen Z, Visel A, Kriegstein A, Shen Y, Pilaz LJ, Chen B, A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex. Proc Natl Acad Sci U S A. 2024 May 14;121(20):e2321711121 |
1 | J:348634 Lin L, Zhao J, Kubota N, Li Z, Lam YL, Nguyen LP, Yang L, Pokharel SP, Blue SM, Yee BA, Chen R, Yeo GW, Chen CW, Chen L, Zheng S, Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size. Neuron. 2024 Apr 22; |
1 | J:160533 Lizarraga SB, Margossian SP, Harris MH, Campagna DR, Han AP, Blevins S, Mudbhary R, Barker JE, Walsh CA, Fleming MD, Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors. Development. 2010 Jun;137(11):1907-17 |
1 | J:240674 Lu HC, Tan Q, Rousseaux MW, Wang W, Kim JY, Richman R, Wan YW, Yeh SY, Patel JM, Liu X, Lin T, Lee Y, Fryer JD, Han J, Chahrour M, Finnell RH, Lei Y, Zurita-Jimenez ME, Ahimaz P, Anyane-Yeboa K, Van Maldergem L, Lehalle D, Jean-Marcais N, Mosca-Boidron AL, Thevenon J, Cousin MA, Bro DE, Lanpher BC, Klee EW, Alexander N, Bainbridge MN, Orr HT, Sillitoe RV, Ljungberg MC, Liu Z, Schaaf CP, Zoghbi HY, Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nat Genet. 2017 Apr;49(4):527-536 |
1 | J:336095 Lupan BM, Solecki RA, Musso CM, Alsina FC, Silver DL, The exon junction complex component EIF4A3 is essential for mouse and human cortical progenitor mitosis and neurogenesis. Development. 2023 May 15;150(10) |
1 | J:362502 Lv Y, Zou W, Li L, Zhang S, Liang J, Pu J, Jiao J, IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex. Adv Sci (Weinh). 2025 Mar 7;:e2501593 |
1* | J:333071 Ma H, Su L, Xia W, Wang W, Tan G, Jiao J, MacroH2A1.2 deficiency leads to neural stem cell differentiation defects and autism-like behaviors. EMBO Rep. 2021 Jul 5;22(7):e52150 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:179730 Mairet-Coello G, Tury A, Van Buskirk E, Robinson K, Genestine M, Dicicco-Bloom E, p57KIP2 regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortex. Development. 2012 Feb;139(3):475-87 |
1 | J:156171 Manuel M, Martynoga B, Yu T, West JD, Mason JO, Price DJ, The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice. Development. 2010 Feb;137(3):487-97 |
1 | J:328992 Manuel M, Tan KB, Kozic Z, Molinek M, Marcos TS, Razak MFA, Dobolyi D, Dobie R, Henderson BEP, Henderson NC, Chan WK, Daw MI, Mason JO, Price DJ, Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals. PLoS Biol. 2022 Sep;20(9):e3001563 |
2 | J:130570 Mao CA, Kiyama T, Pan P, Furuta Y, Hadjantonakis AK, Klein WH, Eomesodermin, a target gene of Pou4f2, is required for retinal ganglion cell and optic nerve development in the mouse. Development. 2008 Jan;135(2):271-80 |
1* | J:257918 Massimino L, Flores-Garcia L, Di Stefano B, Colasante G, Icoresi-Mazzeo C, Zaghi M, Hamilton BA, Sessa A, TBR2 antagonizes retinoic acid dependent neuronal differentiation by repressing Zfp423 during corticogenesis. Dev Biol. 2018 Feb 15;434(2):231-248 |
1 | J:341276 Matrongolo MJ, Ho-Nguyen KT, Jain M, Ang PS, Reddy A, Schaper S, Tischfield MA, Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice. Development. 2023 Sep 15;150(18):dev201381 |
1 | J:171254 Matsumoto A, Onoyama I, Sunabori T, Kageyama R, Okano H, Nakayama KI, Fbxw7-dependent Degradation of Notch Is Required for Control of 'Stemness' and Neuronal-Glial Differentiation in Neural Stem Cells. J Biol Chem. 2011 Apr 15;286(15):13754-64 |
1 | J:286398 Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, Furuse T, Shibuya H, Yasuda Y, Yamamori H, Fujimoto M, Nagayasu K, Yamamoto K, Kitagawa K, Miura H, Gotoda-Nishimura N, Igarashi H, Hayashida M, Baba M, Kondo M, Hasebe S, Ueshima K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Iguchi T, Sato M, Yamaguchi S, Tamura M, Wakana S, Yoshiki A, Watabe AM, Okano H, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T, Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes. Nat Commun. 2020 Feb 26;11(1):859 |
1 | J:306233 Mesman S, Bakker R, Smidt MP, Tcf4 is required for correct brain development during embryogenesis. Mol Cell Neurosci. 2020 Jul;106:103502 |
1 | J:331478 Monko T, Rebertus J, Stolley J, Salton SR, Nakagawa Y, Thalamocortical axons regulate neurogenesis and laminar fates in the early sensory cortex. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2201355119 |
1 | J:346596 Mubuchi A, Takechi M, Nishio S, Matsuda T, Itoh Y, Sato C, Kitajima K, Kitagawa H, Miyata S, Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons. Elife. 2024 Mar 21;12 |
1 | J:335191 Munz M, Bharioke A, Kosche G, Moreno-Juan V, Brignall A, Rodrigues TM, Graff-Meyer A, Ulmer T, Haeuselmann S, Pavlinic D, Ledergerber N, Gross-Scherf B, Rozsa B, Krol J, Picelli S, Cowan CS, Roska B, Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex. Cell. 2023 Apr 27;186(9):1930-1949.e31 |
1 | J:309437 Nakagawa N, Li J, Yabuno-Nakagawa K, Eom TY, Cowles M, Mapp T, Taylor R, Anton ES, APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017 Aug 15;31(16):1679-1692 |
1 | J:330740 Narayanan R, Pham L, Kerimoglu C, Watanabe T, Castro Hernandez R, Sokpor G, Ulmke PA, Kiszka KA, Tonchev AB, Rosenbusch J, Seong RH, Teichmann U, Frahm J, Fischer A, Bonn S, Stoykova A, Staiger JF, Tuoc T, Chromatin Remodeling BAF155 Subunit Regulates the Genesis of Basal Progenitors in Developing Cortex. iScience. 2018 Jun 29;4:109-126 |
1 | J:272073 Nicola Z, Fabel K, Kempermann G, Development of the adult neurogenic niche in the hippocampus of mice. Front Neuroanat. 2015;9:53 |
1 | J:240892 Nitarska J, Smith JG, Sherlock WT, Hillege MM, Nott A, Barshop WD, Vashisht AA, Wohlschlegel JA, Mitter R, Riccio A, A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development. Cell Rep. 2016 Nov 01;17(6):1683-1698 |
1 | J:285050 Ochi S, Imaizumi Y, Shimojo H, Miyachi H, Kageyama R, Oscillatory expression of Hes1 regulates cell proliferation and neuronal differentiation in the embryonic brain. Development. 2020 Feb 26;147(4):dev182204 |
1 | J:354217 Ohyama K, Shinohara HM, Takayama N, Ogawa R, Omura S, Hayashida M, Takahashi T, Differentiation stage-specific expression of transcriptional regulators for epithelial mesenchymal transition in dentate granule progenitors. Front Neurosci. 2024;18:1425849 |
1 | J:150768 Okado H, Ohtaka-Maruyama C, Sugitani Y, Fukuda Y, Ishida R, Hirai S, Miwa A, Takahashi A, Aoki K, Mochida K, Suzuki O, Honda T, Nakajima K, Ogawa M, Terashima T, Matsuda J, Kawano H, Kasai M, The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Dev Biol. 2009 Jul 15;331(2):140-51 |
1 | J:331057 Parichha A, Datta D, Suresh V, Chatterjee M, Holtzman MJ, Tole S, Dentate gyrus morphogenesis is regulated by beta-catenin function in hem-derived fimbrial glia. Development. 2022 Nov 1;149(21):dev200953 |
1 | J:320719 Parichha A, Suresh V, Chatterjee M, Kshirsagar A, Ben-Reuven L, Olender T, Taketo MM, Radosevic V, Bobic-Rasonja M, Trnski S, Holtzman MJ, Jovanov-Milosevic N, Reiner O, Tole S, Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate. Nat Commun. 2022 Feb 2;13(1):633 |
1 | J:241853 Parisot J, Flore G, Bertacchi M, Studer M, COUP-TFI mitotically regulates production and migration of dentate granule cells and modulates hippocampal Cxcr4 expression. Development. 2017 Jun 01;144(11):2045-2058 |
1 | J:287008 Pearson CA, Moore DM, Tucker HO, Dekker JD, Hu H, Miquelajauregui A, Novitch BG, Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates. Cell Rep. 2020 Feb 11;30(6):1964-1981.e3 |
1* | J:360369 Pelenyi A, Atterton C, Jones J, Currey L, Al-Khalily M, Wright L, Kurniawan ND, Thor S, Piper M, Expression of the Hippo pathway effector, TEAD1, within the developing murine forebrain. Gene Expr Patterns. 2024 Dec;54:119384 |
2 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:287604 Ratie L, Desmaris E, Garcia-Moreno F, Hoerder-Suabedissen A, Kelman A, Theil T, Bellefroid EJ, Molnar Z, Loss of Dmrt5 Affects the Formation of the Subplate and Early Corticogenesis. Cereb Cortex. 2020 May 14;30(5):3296-3312 |
1 | J:217395 Ritchie K, Watson LA, Davidson B, Jiang Y, Berube NG, ATRX is required for maintenance of the neuroprogenitor cell pool in the embryonic mouse brain. Biol Open. 2014;3(12):1158-63 |
1 | J:187684 Rodriguez M, Choi J, Park S, Sockanathan S, Gde2 regulates cortical neuronal identity by controlling the timing of cortical progenitor differentiation. Development. 2012 Oct;139(20):3870-9 |
1 | J:353313 Roussat M, Jungas T, Audouard C, Omerani S, Medevielle F, Agius E, Davy A, Pituello F, Bel-Vialar S, Control of G(2) Phase Duration by CDC25B Modulates the Switch from Direct to Indirect Neurogenesis in the Neocortex. J Neurosci. 2023 Feb 15;43(7):1154-1165 |
1 | J:341708 Saha S, Jungas TT, Ohayon D, Audouard C, Ye T, Fawal MA, Davy A, Dihydrofolate reductase activity controls neurogenic transitions in the developing neocortex. Development. 2023 Oct 15;150(20):dev201696 |
1 | J:154951 Sahara S, O'Leary DD, Fgf10 regulates transition period of cortical stem cell differentiation to radial glia controlling generation of neurons and basal progenitors. Neuron. 2009 Jul 16;63(1):48-62 |
1 | J:137882 Samuels IS, Karlo JC, Faruzzi AN, Pickering K, Herrup K, Sweatt JD, Saitta SC, Landreth GE, Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function. J Neurosci. 2008 Jul 2;28(27):6983-95 |
1 | J:241756 Sanchez-Camacho C, Ortega JA, Ocana I, Alcantara S, Bovolenta P, Appropriate Bmp7 levels are required for the differentiation of midline guidepost cells involved in corpus callosum formation. Dev Neurobiol. 2011 May;71(5):337-50 |
1 | J:154601 Seuntjens E, Nityanandam A, Miquelajauregui A, Debruyn J, Stryjewska A, Goebbels S, Nave KA, Huylebroeck D, Tarabykin V, Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors. Nat Neurosci. 2009 Nov;12(11):1373-80 |
1 | J:278483 Shi L, Qalieh A, Lam MM, Keil JM, Kwan KY, Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion. Nat Commun. 2019 Jun 13;10(1):2588 |
1 | J:213479 Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, Yoshida N, PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Cereb Cortex. 2013 Aug;23(8):1824-35 |
1* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
1 | J:283783 Shu P, Wu C, Ruan X, Liu W, Hou L, Fu H, Wang M, Liu C, Zeng Y, Chen P, Yin B, Yuan J, Qiang B, Peng X, Zhong W, Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell. 2019 Jun 3;49(5):764-785.e4 |
1 | J:159625 Silver DL, Watkins-Chow DE, Schreck KC, Pierfelice TJ, Larson DM, Burnetti AJ, Liaw HJ, Myung K, Walsh CA, Gaiano N, Pavan WJ, The exon junction complex component Magoh controls brain size by regulating neural stem cell division. Nat Neurosci. 2010 May;13(5):551-8 |
1* | J:324710 Stanton-Turcotte D, Hsu K, Moore SA, Yamada M, Fawcett JP, Iulianella A, Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development. J Neurosci. 2022 May 11;42(19):3931-3948 |
1 | J:159839 Stevens HE, Smith KM, Maragnoli ME, Fagel D, Borok E, Shanabrough M, Horvath TL, Vaccarino FM, Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits. J Neurosci. 2010 Apr 21;30(16):5590-602 |
1 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
1* | J:203065 Sugiyama T, Osumi N, Katsuyama Y, The germinal matrices in the developing dentate gyrus are composed of neuronal progenitors at distinct differentiation stages. Dev Dyn. 2013 Dec;242(12):1442-53 |
1 | J:216104 Sugiyama T, Osumi N, Katsuyama Y, A novel cell migratory zone in the developing hippocampal formation. J Comp Neurol. 2014 Oct 15;522(15):3520-38 |
1 | J:320749 Sun YY, Chen WJ, Huang ZP, Yang G, Wu ML, Xu DE, Yang WL, Luo YC, Xiao ZC, Xu RX, Ma QH, TRIM32 Deficiency Impairs the Generation of Pyramidal Neurons in Developing Cerebral Cortex. Cells. 2022 Jan 28;11(3) |
2 | J:188109 Tan SL, Nishi M, Ohtsuka T, Matsui T, Takemoto K, Kamio-Miura A, Aburatani H, Shinkai Y, Kageyama R, Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development. Development. 2012 Oct;139(20):3806-16 |
1 | J:360973 Tang I, Nisal A, Reed A, Ware TB, Johansen A, Zaki MS, Cravatt BF, Gleeson JG, Lipidomic profiling of mouse brain and human neuron cultures reveals a role for Mboat7 in mTOR-dependent neuronal migration. Sci Transl Med. 2025 Jan;17(779):eadp5247 |
1 | J:191783 Teissier A, Waclaw RR, Griveau A, Campbell K, Pierani A, Tangentially migrating transient glutamatergic neurons control neurogenesis and maintenance of cerebral cortical progenitor pools. Cereb Cortex. 2012 Feb;22(2):403-16 |
1 | J:279607 Tonchev AB, Tuoc TC, Rosenthal EH, Studer M, Stoykova A, Zbtb20 modulates the sequential generation of neuronal layers in developing cortex. Mol Brain. 2016 Jun 9;9(1):65 |
1 | J:268904 Tripathy R, Leca I, van Dijk T, Weiss J, van Bon BW, Sergaki MC, Gstrein T, Breuss M, Tian G, Bahi-Buisson N, Paciorkowski AR, Pagnamenta AT, Wenninger-Weinzierl A, Martinez-Reza MF, Landler L, Lise S, Taylor JC, Terrone G, Vitiello G, Del Giudice E, Brunetti-Pierri N, D'Amico A, Reymond A, Voisin N, Bernstein JA, Farrelly E, Kini U, Leonard TA, Valence S, Burglen L, Armstrong L, Hiatt SM, Cooper GM, Aldinger KA, Dobyns WB, Mirzaa G, Pierson TM, Baas F, Chelly J, Cowan NJ, Keays DA, Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations. Neuron. 2018 Dec 19;100(6):1354-1368.e5 |
1* | J:314103 Ulmke PA, Sakib MS, Ditte P, Sokpor G, Kerimoglu C, Pham L, Xie Y, Mao X, Rosenbusch J, Teichmann U, Nguyen HP, Fischer A, Eichele G, Staiger JF, Tuoc T, Molecular Profiling Reveals Involvement of ESCO2 in Intermediate Progenitor Cell Maintenance in the Developing Mouse Cortex. Stem Cell Reports. 2021 Apr 13;16(4):968-984 |
1 | J:293532 Vaid S, Camp JG, Hersemann L, Eugster Oegema C, Heninger AK, Winkler S, Brandl H, Sarov M, Treutlein B, Huttner WB, Namba T, A novel population of Hopx-dependent basal radial glial cells in the developing mouse neocortex. Development. 2018 Oct 18;145(20):dev169276 |
1 | J:304564 Venkataramanappa S, Schutz D, Saaber F, Kumar PA, Abe P, Schulz S, Stumm R, The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS Genet. 2021 Mar;17(3):e1009441 |
1 | J:309451 Vinsland E, Baskaran P, Mihaylov SR, Hobbs C, Wood H, Bouybayoune I, Shah K, Houart C, Tee AR, Murn J, Fernandes C, Bateman JM, The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021 Aug 11;11(1):16299 |
1 | J:221658 Vithayathil J, Pucilowska J, Goodnough LH, Atit RP, Landreth GE, Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation. J Neurosci. 2015 Apr 29;35(17):6836-48 |
1* | J:143543 Vogel T, Gruss P, Expression of Leukaemia associated transcription factor Af9/Mllt3 in the cerebral cortex of the mouse. Gene Expr Patterns. 2009 Feb;9(2):83-93 |
1* | J:316179 Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y, An epigenetic circuit controls neurogenic programs during neocortex development. Development. 2021;148:dev199772 |
1 | J:265679 Wang B, Joo JH, Mount R, Teubner BJW, Krenzer A, Ward AL, Ichhaporia VP, Adams EJ, Khoriaty R, Peters ST, Pruett-Miller SM, Zakharenko SS, Ginsburg D, Kundu M, The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018 Aug 1;128(8):3319-3332 |
1 | J:303486 Wang J, Li T, Wang JL, Xu Z, Meng W, Wu QF, Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions. Cell Rep. 2020 Dec 15;33(11):108495 |
1 | J:339243 Wang J, Wang A, Tian K, Hua X, Zhang B, Zheng Y, Kong X, Li W, Xu L, Wang J, Li Z, Liu Y, Zhou Y, A Ctnnb1 enhancer regulates neocortical neurogenesis by controlling the abundance of intermediate progenitors. Cell Discov. 2022 Aug 2;8(1):74 |
1 | J:363654 Wang J, Zhang J, Li J, Gao Q, Chen J, Jia C, Gu X, Cortex-Specific Tmem169 Deficiency Induces Defects in Cortical Neuron Development and Autism-Like Behaviors in Mice. J Neurosci. 2025 Feb 26;45(9) |
1 | J:238248 Wang L, Hou S, Han YG, Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex. Nat Neurosci. 2016 Jul;19(7):888-96 |
1 | J:334078 Wang L, Park JY, Liu F, Olesen KM, Hou S, Peng JC, Infield J, Levesque AC, Wang YD, Jin H, Fan Y, Connelly PJ, Pruett-Miller SM, Hu MG, Hinds PW, Han YG, A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2206147119 |
1 | J:206929 Watson LA, Wang X, Elbert A, Kernohan KD, Galjart N, Berube NG, Dual Effect of CTCF Loss on Neuroprogenitor Differentiation and Survival. J Neurosci. 2014 Feb 19;34(8):2860-70 |
1 | J:227426 Wiegreffe C, Simon R, Peschkes K, Kling C, Strehle M, Cheng J, Srivatsa S, Liu P, Jenkins NA, Copeland NG, Tarabykin V, Britsch S, Bcl11a (Ctip1) Controls Migration of Cortical Projection Neurons through Regulation of Sema3c. Neuron. 2015 Jul 15;87(2):311-25 |
1 | J:325764 Xia Y, Zhang Y, Xu M, Zou X, Gao J, Ji MH, Chen G, Presenilin enhancer 2 is crucial for the transition of apical progenitors into neurons but into not basal progenitors in the developing hippocampus. Development. 2022 May 15;149(10):dev200272 |
1 | J:273281 Xu D, Yao M, Wang Y, Yuan L, Hoeck JD, Yu J, Liu L, Yeap YYC, Zhang W, Zhang F, Feng Y, Ma T, Wang Y, Ng DCH, Niu X, Su B, Behrens A, Xu Z, MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis. PLoS Biol. 2018 Dec;16(12):e2006613 |
1 | J:285763 Xu M, Han X, Liu R, Li Y, Qi C, Yang Z, Zhao C, Gao J, PDK1 Deficit Impairs the Development of the Dentate Gyrus in Mice. Cereb Cortex. 2019 Mar 1;29(3):1185-1198 |
1 | J:270427 Yabut OR, Fernandez G, Huynh T, Yoon K, Pleasure SJ, Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis. Cell Rep. 2015 Sep 29;12(12):2021-34 |
1 | J:282462 Yabut OR, Ng HX, Fernandez G, Yoon K, Kuhn J, Pleasure SJ, Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors. J Dev Biol. 2016 Dec;4(4) |
1* | J:214315 Yamada M, Clark J, Iulianella A, MLLT11/AF1q is differentially expressed in maturing neurons during development. Gene Expr Patterns. 2014 Jul;15(2):80-7 |
1 | J:345074 Yamanaka T, Kurosawa M, Yoshida A, Shimogori T, Hiyama A, Maity SN, Hattori N, Matsui H, Nukina N, The transcription factor NF-YA is crucial for neural progenitor maintenance during brain development. J Biol Chem. 2024 Jan 8;300(2):105629 |
1 | J:177905 Yamasaki T, Kawasaki H, Arakawa S, Shimizu K, Shimizu S, Reiner O, Okano H, Nishina S, Azuma N, Penninger JM, Katada T, Nishina H, Stress-Activated Protein Kinase MKK7 Regulates Axon Elongation in the Developing Cerebral Cortex. J Neurosci. 2011 Nov 16;31(46):16872-16883 |
1 | J:339368 Yao F, Huang S, Liu J, Tan C, Xu M, Wang D, Huang M, Zhu Y, Huang X, He S, Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis. Cell Death Dis. 2023 Aug 23;14(8):543 |
1 | J:224155 You L, Yan K, Zhou J, Zhao H, Bertos NR, Park M, Wang E, Yang XJ, The lysine acetyltransferase activator Brpf1 governs dentate gyrus development through neural stem cells and progenitors. PLoS Genet. 2015 Mar;11(3):e1005034 |
1 | J:363160 Yuizumi N, Harada Y, Kuniya T, Sunabori T, Koike M, Wakabayashi M, Ishihama Y, Suzuki Y, Kawaguchi D, Gotoh Y, Maintenance of neural stem-progenitor cells by the lysosomal biosynthesis regulators TFEB and TFE3 in the embryonic mouse telencephalon. Stem Cells. 2021 Jul;39(7):929-944 |
1 | J:341689 Zhang B, Zhao C, Shen W, Li W, Zheng Y, Kong X, Wang J, Wu X, Zeng T, Liu Y, Zhou Y, KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors. Nat Commun. 2023 Oct 14;14(1):6489 |
1 | J:334113 Zhang F, Yoon K, Zhang DY, Kim NS, Ming GL, Song H, Epitranscriptomic regulation of cortical neurogenesis via Mettl8-dependent mitochondrial tRNA m(3)C modification. Cell Stem Cell. 2023 Mar 2;30(3):300-311.e11 |
1 | J:299730 Zhang L, Jing H, Li H, Chen W, Luo B, Zhang H, Dong Z, Li L, Su H, Xiong WC, Mei L, Neddylation is critical to cortical development by regulating Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26448-26459 |
1 | J:328995 Zhang SF, Dai SK, Du HZ, Wang H, Li XG, Tang Y, Liu CM, The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis. Stem Cell Reports. 2022 Sep 13;17(9):2064-2080 |
2 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
1 | J:324298 Zhou J, Liu G, Zhang X, Wu C, Ma M, Wu J, Hou L, Yin B, Qiang B, Shu P, Peng X, Comparison of the Spatiotemporal Expression Patterns of Three Cre Lines, Emx1IRES-Cre, D6-Cre and hGFAP-Cre, Commonly Used in Neocortical Development Research. Cereb Cortex. 2022 Apr 5;32(8):1668-1681 |
Ep300 E1A binding protein p300 (Synonyms: KAT3B, p300) | |
Results | Reference |
1* | J:147999 Chen G, Zhu J, Lv T, Wu G, Sun H, Huang X, Tian J, Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts. J Biomed Sci. 2009;16:24 |
1 | J:181099 Chen Z, Gao B, Zhou X, Expression patterns of histone acetyltransferases p300 and CBP during murine tooth development. In Vitro Cell Dev Biol Anim. 2012 Jan;48(1):61-8 |
1 | J:331267 de Thonel A, Ahlskog JK, Daupin K, Dubreuil V, Berthelet J, Chaput C, Pires G, Leonetti C, Abane R, Barris LC, Leray I, Aalto AL, Naceri S, Cordonnier M, Benasolo C, Sanial M, Duchateau A, Vihervaara A, Puustinen MC, Miozzo F, Fergelot P, Lebigot E, Verloes A, Gressens P, Lacombe D, Gobbo J, Garrido C, Westerheide SD, David L, Petitjean M, Taboureau O, Rodrigues-Lima F, Passemard S, Saberan-Djoneidi D, Nguyen L, Lancaster M, Sistonen L, Mezger V, CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder. Nat Commun. 2022 Nov 16;13(1):7002 |
1* | J:60120 Partanen M, Motoyama J, Hui CC, Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis. Int J Dev Biol. 1999 Sep;43(6):487-94 |
1* | J:47301 Yao TP, Oh SP, Fuchs M, Zhou ND, Ch'ng LE, Newsome D, Bronson RT , Li E , Livingston DM , Eckner R, Gene dosage-dependent embryonic development and proliferation defects in mice lacking the transcriptional integrator p300. Cell. 1998 May 1;93(3):361-72 |
Epas1 endothelial PAS domain protein 1 (Synonyms: bHLHe73, HIF2A, HIF-2alpha, Hif like protein, HLF, HRF, hypoxia inducible transcription factor 2alpha, MOP2) | |
Results | Reference |
1* | J:180152 Bridges JP, Lin S, Ikegami M, Shannon JM, Conditional hypoxia inducible factor-1alpha induction in embryonic pulmonary epithelium impairs maturation and augments lymphangiogenesis. Dev Biol. 2012 Feb 1;362(1):24-41 |
1 | J:77480 Compernolle V, Brusselmans K, Acker T, Hoet P, Tjwa M, Beck H, Plaisance S, Dor Y, Keshet E, Lupu F, Nemery B, Dewerchin M, Van Veldhoven P, Plate K, Moons L, Collen D, Carmeliet P, Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice. Nat Med. 2002 Jul;8(7):702-10 |
1 | J:302486 Jiang X, Tian W, Granucci EJ, Tu AB, Kim D, Dahms P, Pasupneti S, Peng G, Kim Y, Lim AH, Espinoza FH, Cribb M, Dixon JB, Rockson SG, Semenza GL, Nicolls MR, Decreased lymphatic HIF-2alpha accentuates lymphatic remodeling in lymphedema. J Clin Invest. 2020 Oct 1;130(10):5562-5575 |
1* | J:331512 Kimura S, Takeshita N, Oyanagi T, Seki D, Jiang W, Hidaka K, Fukumoto S, Takahashi I, Takano-Yamamoto T, HIF-2alpha Inhibits Ameloblast Differentiation via Hey2 in Tooth Development. J Dent Res. 2022 Dec;101(13):1637-1644 |
Epb41 erythrocyte membrane protein band 4.1 (Synonyms: 4.1R, D4Ertd442e, Elp-1, Elp1, Epb4.1) | |
Results | Reference |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
Epb42 erythrocyte membrane protein band 4.2 (Synonyms: Epb4.2) | |
Results | Reference |
2* | J:45320 Zhu L, Kahwash SB, Chang LS, Developmental expression of mouse erythrocyte protein 4.2 mRNA: evidence for specific expression in erythroid cells. Blood. 1998 Jan 15;91(2):695-705 |
Epcam epithelial cell adhesion molecule (Synonyms: CD326, EGP-2, Egp314, Ep-CAM, EpCAM, EpCAM1, GA733-2, gp40, Ly74, panepithelial glycoprotein 314, Tacstd1, TROP1) | |
Results | Reference |
1 | J:241637 Azzarelli R, Hurley C, Sznurkowska MK, Rulands S, Hardwick L, Gamper I, Ali F, McCracken L, Hindley C, McDuff F, Nestorowa S, Kemp R, Jones K, Gottgens B, Huch M, Evan G, Simons BD, Winton D, Philpott A, Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation. Dev Cell. 2017 May 08;41(3):274-286.e5 |
1 | J:361670 Defamie V, Aliar K, Sarkar S, Vyas F, Shetty R, Reddy Narala S, Fang H, Saw S, Tharmapalan P, Sanchez O, Knox JJ, Waterhouse PD, Khokha R, Metalloproteinase inhibitors regulate biliary progenitor cells through sDLK1 in organoid models of liver injury. J Clin Invest. 2024 Dec 19;135(3) |
1* | J:189751 Hara T, Shitara S, Imai K, Miyachi H, Kitano S, Yao H, Tani-ichi S, Ikuta K, Identification of IL-7-producing cells in primary and secondary lymphoid organs using IL-7-GFP knock-in mice. J Immunol. 2012 Aug 15;189(4):1577-84 |
1 | J:332247 Huang XT, Li T, Li T, Xing S, Tian JZ, Ding YF, Cai SL, Yang YS, Wood C, Yang JS, Yang WJ, Embryogenic stem cell-derived intestinal crypt fission directs de novo crypt genesis. Cell Rep. 2022 Dec 13;41(11):111796 |
2 | J:346767 Lan Q, Trela E, Lindstrom R, Satta JP, Kaczynska B, Christensen MM, Holzenberger M, Jernvall J, Mikkola ML, Mesenchyme instructs growth while epithelium directs branching in the mouse mammary gland. Elife. 2024 Mar 5;13 |
2 | J:321068 Maimets M, Pedersen MT, Guiu J, Dreier J, Thodberg M, Antoku Y, Schweiger PJ, Rib L, Bressan RB, Miao Y, Garcia KC, Sandelin A, Serup P, Jensen KB, Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling. Nat Commun. 2022 Feb 7;13(1):715 |
1 | J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461 |
2 | J:345231 Satta JP, Lan Q, Taketo MM, Mikkola ML, Stabilization of Epithelial beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis. J Invest Dermatol. 2023 Dec 28; |
1 | J:353338 Satta JP, Lindstrom R, Myllymaki SM, Lan Q, Trela E, Prunskaite-Hyyrylainen R, Kaczynska B, Voutilainen M, Kuure S, Vainio SJ, Mikkola ML, Exploring the principles of embryonic mammary gland branching morphogenesis. Development. 2024 Aug 1;151(15):dev202179 |
1* | J:152812 Tanaka M, Okabe M, Suzuki K, Kamiya Y, Tsukahara Y, Saito S, Miyajima A, Mouse hepatoblasts at distinct developmental stages are characterized by expression of EpCAM and DLK1: drastic change of EpCAM expression during liver development. Mech Dev. 2009 Aug-Sep;126(8-9):665-76 |
1 | J:271268 Yui S, Azzolin L, Maimets M, Pedersen MT, Fordham RP, Hansen SL, Larsen HL, Guiu J, Alves MRP, Rundsten CF, Johansen JV, Li Y, Madsen CD, Nakamura T, Watanabe M, Nielsen OH, Schweiger PJ, Piccolo S, Jensen KB, YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration. Cell Stem Cell. 2018 Jan 4;22(1):35-49.e7 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Epdr1 ependymin related 1 (Synonyms: Epdr1, Epdr2, MERP-1, MERP-2, MERP2, Ucc1) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Epgn epithelial mitogen (Synonyms: 2310069M11Rik, epigen) | |
Results | Reference |
1* | J:316873 Kochupurakkal BS, Harari D, Di-Segni A, Maik-Rachline G, Lyass L, Gur G, Kerber G, Citri A, Lavi S, Eilam R, Chalifa-Caspi V, Eshhar Z, Pikarsky E, Pinkas-Kramarski R, Bacus SS, Yarden Y, Epigen, the last ligand of ErbB receptors, reveals intricate relationships between affinity and mitogenicity. J Biol Chem. 2005 Mar 4;280(9):8503-12 |
1 | J:163484 Lin MH, Chang KW, Lin SC, Miner JH, Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling. Dev Biol. 2010 Aug 15;344(2):707-19 |
Epha1 Eph receptor A1 (Synonyms: 5730453L17Rik, Eph, Esk) | |
Results | Reference |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1* | J:231672 Xavier GM, Miletich I, Cobourne MT, Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue. Front Physiol. 2016;7:60 |
1 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
Epha2 Eph receptor A2 (Synonyms: Eck, Myk2, Sek-2, Sek2) | |
Results | Reference |
1 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
2 | J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134 |
1 | J:95080 Luukko K, Loes S, Kvinnsland IH, Kettunen P, Expression of ephrin-A ligands and EphA receptors in the developing mouse tooth and its supporting tissues. Cell Tissue Res. 2005 Jan;319(1):143-52 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1* | J:231672 Xavier GM, Miletich I, Cobourne MT, Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue. Front Physiol. 2016;7:60 |
Epha3 Eph receptor A3 (Synonyms: Cek4, End3, Hek, Hek4, Mek4, Tyro4) | |
Results | Reference |
1 | J:72872 Bain G, Mansergh FC, Wride MA, Hance JE, Isogawa A, Rancourt SL, Ray WJ, Yoshimura Y, Tsuzuki T, Gottlieb DI, Rancourt DE, ES cell neural differentiation reveals a substantial number of novel ESTs. Funct Integr Genomics. 2000 Sep;1(2):127-139 |
1* | J:154889 Deschamps C, Faideau M, Jaber M, Gaillard A, Prestoz L, Expression of ephrinA5 during development and potential involvement in the guidance of the mesostriatal pathway. Exp Neurol. 2009 Oct;219(2):466-80 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
4* | J:99710 Kudo C, Ajioka I, Hirata Y, Nakajima K, Expression profiles of EphA3 at both the RNA and protein level in the developing mammalian forebrain. J Comp Neurol. 2005 Jul 4;487(3):255-69 |
1 | J:95080 Luukko K, Loes S, Kvinnsland IH, Kettunen P, Expression of ephrin-A ligands and EphA receptors in the developing mouse tooth and its supporting tissues. Cell Tissue Res. 2005 Jan;319(1):143-52 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1* | J:231672 Xavier GM, Miletich I, Cobourne MT, Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue. Front Physiol. 2016;7:60 |
Epha4 Eph receptor A4 (Synonyms: 2900005C20Rik, Cek8, Hek8, rb, Sek, Sek1, Tyro1) | |
Results | Reference |
2 | J:179898 Coate TM, Raft S, Zhao X, Ryan AK, Crenshaw EB 3rd, Kelley MW, Otic Mesenchyme Cells Regulate Spiral Ganglion Axon Fasciculation through a Pou3f4/EphA4 Signaling Pathway. Neuron. 2012 Jan 12;73(1):49-63 |
1 | J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400 |
1 | J:44591 Garel S, Marin F, Grosschedl R, Charnay P, Ebf1 controls early cell differentiation in the embryonic striatum. Development. 1999 Dec;126(23):5285-94 |
1* | J:79830 Garel S, Yun K, Grosschedl R, Rubenstein JL, The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development. 2002 Dec;129(24):5621-34 |
2 | J:217584 Gerstmann K, Pensold D, Symmank J, Khundadze M, Hubner CA, Bolz J, Zimmer G, Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions. Development. 2015 Jan 1;142(1):140-50 |
1 | J:330742 Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM, In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022 Oct 17;132(20):e156955 |
1 | J:76573 Karam SD, Dottori M, Ogawa K, Henderson JT, Boyd AW, Pasquale EB, Bothwell M, EphA4 is not required for Purkinje cell compartmentation. Brain Res Dev Brain Res. 2002 Apr 30;135(1-2):29-38 |
1 | J:95080 Luukko K, Loes S, Kvinnsland IH, Kettunen P, Expression of ephrin-A ligands and EphA receptors in the developing mouse tooth and its supporting tissues. Cell Tissue Res. 2005 Jan;319(1):143-52 |
1 | J:104532 Mendes SW, Henkemeyer M, Liebl DJ, Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J Neurosci. 2006 Jan 18;26(3):882-92 |
1* | J:138785 Passante L, Gaspard N, Degraeve M, Frisen J, Kullander K, De Maertelaer V, Vanderhaeghen P, Temporal regulation of ephrin/Eph signalling is required for the spatial patterning of the mammalian striatum. Development. 2008 Oct;135(19):3281-90 |
1 | J:109567 Shen WB, Plachez C, Mongi AS, Richards LJ, Identification of candidate genes at the corticoseptal boundary during development. Gene Expr Patterns. 2006 Jun;6(5):471-81 |
2* | J:206575 Steinecke A, Gampe C, Zimmer G, Rudolph J, Bolz J, EphA/ephrin A reverse signaling promotes the migration of cortical interneurons from the medial ganglionic eminence. Development. 2014 Jan;141(2):460-71 |
1 | J:153504 Torii M, Hashimoto-Torii K, Levitt P, Rakic P, Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling. Nature. 2009 Sep 24;461(7263):524-8 |
1 | J:302307 Tran-Anh K, Zhang J, Nguyen-Minh VT, Fujita H, Hirata T, Sugihara I, Common Origin of the Cerebellar Dual Somatotopic Areas Revealed by Tracking Embryonic Purkinje Cell Clusters with Birthdate Tagging. eNeuro. 2020 Nov/Dec;7(6):ENEURO.0251-20.2020 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1* | J:251975 Vibulyaseck S, Fujita H, Luo Y, Tran AK, Oh-Nishi A, Ono Y, Hirano S, Sugihara I, Spatial rearrangement of Purkinje cell subsets forms the transverse and longitudinal compartmentalization in the mouse embryonic cerebellum. J Comp Neurol. 2017 Oct 1;525(14):2971-2990 |
1* | J:231672 Xavier GM, Miletich I, Cobourne MT, Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue. Front Physiol. 2016;7:60 |
1 | J:159315 Xie Z, Ma X, Ji W, Zhou G, Lu Y, Xiang Z, Wang YX, Zhang L, Hu Y, Ding YQ, Zhang WJ, Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6510-5 |
Epha5 Eph receptor A5 (Synonyms: bsk, Cek7, Ehk1, Els1, Hek7, Rek7) | |
Results | Reference |
1* | J:74241 Barbieri AM, Broccoli V, Bovolenta P, Alfano G, Marchitiello A, Mocchetti C, Crippa L, Bulfone A, Marigo V, Ballabio A, Banfi S, Vax2 inactivation in mouse determines alteration of the eye dorsal-ventral axis, misrouting of the optic fibres and eye coloboma. Development. 2002 Feb;129(3):805-13 |
1* | J:154889 Deschamps C, Faideau M, Jaber M, Gaillard A, Prestoz L, Expression of ephrinA5 during development and potential involvement in the guidance of the mesostriatal pathway. Exp Neurol. 2009 Oct;219(2):466-80 |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:153504 Torii M, Hashimoto-Torii K, Levitt P, Rakic P, Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling. Nature. 2009 Sep 24;461(7263):524-8 |
1 | J:180170 Triplett JW, Pfeiffenberger C, Yamada J, Stafford BK, Sweeney NT, Litke AM, Sher A, Koulakov AA, Feldheim DA, Competition is a driving force in topographic mapping. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19060-5 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1* | J:231672 Xavier GM, Miletich I, Cobourne MT, Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue. Front Physiol. 2016;7:60 |
Epha6 Eph receptor A6 (Synonyms: Ehk2, Hek12, m-ehk2) | |
Results | Reference |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:180170 Triplett JW, Pfeiffenberger C, Yamada J, Stafford BK, Sweeney NT, Litke AM, Sher A, Koulakov AA, Feldheim DA, Competition is a driving force in topographic mapping. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19060-5 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1* | J:231672 Xavier GM, Miletich I, Cobourne MT, Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue. Front Physiol. 2016;7:60 |
Epha7 Eph receptor A7 (Synonyms: Cek11, Ebk, Ehk3, Hek11, Mdk1, MDK1) | |
Results | Reference |
2 | J:22410 Ciossek T, Millauer B, Ullrich A, Identification of alternatively spliced mRNAs encoding variants of MDK1, a novel receptor tyrosine kinase expressed in the murine nervous system. Oncogene. 1995 Jan 5;10(1):97-108 |
1* | J:184357 Dye CA, El Shawa H, Huffman KJ, A lifespan analysis of intraneocortical connections and gene expression in the mouse I. Cereb Cortex. 2011 Jun;21(6):1311-30 |
1* | J:79830 Garel S, Yun K, Grosschedl R, Rubenstein JL, The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development. 2002 Dec;129(24):5621-34 |
1 | J:199727 Lokmane L, Proville R, Narboux-Neme N, Gyory I, Keita M, Mailhes C, Lena C, Gaspar P, Grosschedl R, Garel S, Sensory map transfer to the neocortex relies on pretarget ordering of thalamic axons. Curr Biol. 2013 May 6;23(9):810-6 |
1 | J:95080 Luukko K, Loes S, Kvinnsland IH, Kettunen P, Expression of ephrin-A ligands and EphA receptors in the developing mouse tooth and its supporting tissues. Cell Tissue Res. 2005 Jan;319(1):143-52 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1 | J:153504 Torii M, Hashimoto-Torii K, Levitt P, Rakic P, Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling. Nature. 2009 Sep 24;461(7263):524-8 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1* | J:231672 Xavier GM, Miletich I, Cobourne MT, Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue. Front Physiol. 2016;7:60 |
Epha8 Eph receptor A8 (Synonyms: Eek, EphA8, Hek3) | |
Results | Reference |
1 | J:162837 Islam S, Loizides AM, Fialkovich JJ, Grand RJ, Montgomery RK, Developmental expression of Eph and ephrin family genes in mammalian small intestine. Dig Dis Sci. 2010 Sep;55(9):2478-88 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1* | J:231672 Xavier GM, Miletich I, Cobourne MT, Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue. Front Physiol. 2016;7:60 |
Ephb1 Eph receptor B1 (Synonyms: C130099E04Rik, Cek6, Elk, Elkh, Hek6, Net) | |
Results | Reference |
1* | J:60855 Birgbauer E, Cowan CA, Sretavan DW, Henkemeyer M, Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina. Development. 2000 Mar;127(6):1231-41 |
1 | J:315303 Bouche E, Romero-Ortega MI, Henkemeyer M, Catchpole T, Leemhuis J, Frotscher M, May P, Herz J, Bock HH, Reelin induces EphB activation. Cell Res. 2013 Apr;23(4):473-90 |
2 | J:184158 Chenaux G, Henkemeyer M, Forward signaling by EphB1/EphB2 interacting with ephrin-B ligands at the optic chiasm is required to form the ipsilateral projection. Eur J Neurosci. 2011 Nov;34(10):1620-33 |
1* | J:134680 Garcia-Frigola C, Carreres MI, Vegar C, Mason C, Herrera E, Zic2 promotes axonal divergence at the optic chiasm midline by EphB1-dependent and -independent mechanisms. Development. 2008 May;135(10):1833-41 |
1 | J:70744 Huang EJ, Liu W, Fritzsch B, Bianchi LM, Reichardt LF, Xiang M, Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons. Development. 2001 Jul;128(13):2421-32 |
1 | J:104532 Mendes SW, Henkemeyer M, Liebl DJ, Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J Neurosci. 2006 Jan 18;26(3):882-92 |
1 | J:272212 Robichaux MA, Chenaux G, Ho HY, Soskis MJ, Greenberg ME, Henkemeyer M, Cowan CW, EphB1 and EphB2 intracellular domains regulate the formation of the corpus callosum and anterior commissure. Dev Neurobiol. 2016 Apr;76(4):405-20 |
1 | J:176056 Thakar S, Chenaux G, Henkemeyer M, Critical roles for EphB and ephrin-B bidirectional signalling in retinocollicular mapping. Nat Commun. 2011;2:431 |
1* | J:142507 Tian NM, Pratt T, Price DJ, Foxg1 regulates retinal axon pathfinding by repressing an ipsilateral program in nasal retina and by causing optic chiasm cells to exert a net axonal growth-promoting activity. Development. 2008 Dec;135(24):4081-9 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1 | J:122943 Williams SE, Grumet M, Colman DR, Henkemeyer M, Mason CA, Sakurai T, A role for Nr-CAM in the patterning of binocular visual pathways. Neuron. 2006 May 18;50(4):535-47 |
1* | J:231672 Xavier GM, Miletich I, Cobourne MT, Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue. Front Physiol. 2016;7:60 |
1 | J:202407 Xiao Y, Woo WM, Nagao K, Li W, Terunuma A, Mukouyama YS, Oro AE, Vogel JC, Brownell I, Perivascular hair follicle stem cells associate with a venule annulus. J Invest Dermatol. 2013 Oct;133(10):2324-31 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
1 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
1 | J:199791 Young TR, Bourke M, Zhou X, Oohashi T, Sawatari A, Fassler R, Leamey CA, Ten-m2 Is Required for the Generation of Binocular Visual Circuits. J Neurosci. 2013 Jul 24;33(30):12490-509 |
Ephb2 Eph receptor B2 (Synonyms: Cek5, Drt, Erk, eteck, Hek5, Nuk, Prkm5, Qek5, Sek3, Tyro5) | |
Results | Reference |
1* | J:74241 Barbieri AM, Broccoli V, Bovolenta P, Alfano G, Marchitiello A, Mocchetti C, Crippa L, Bulfone A, Marigo V, Ballabio A, Banfi S, Vax2 inactivation in mouse determines alteration of the eye dorsal-ventral axis, misrouting of the optic fibres and eye coloboma. Development. 2002 Feb;129(3):805-13 |
1* | J:60855 Birgbauer E, Cowan CA, Sretavan DW, Henkemeyer M, Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina. Development. 2000 Mar;127(6):1231-41 |
1 | J:315303 Bouche E, Romero-Ortega MI, Henkemeyer M, Catchpole T, Leemhuis J, Frotscher M, May P, Herz J, Bock HH, Reelin induces EphB activation. Cell Res. 2013 Apr;23(4):473-90 |
1* | J:150043 Bush JO, Soriano P, Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Genes Dev. 2009 Jul 1;23(13):1586-99 |
1* | J:34200 Henkemeyer M, Orioli D, Henderson JT, Saxton TM, Roder J, Pawson T, Klein R, Nuk controls pathfinding of commissural axons in the mammalian central nervous system. Cell. 1996 Jul 12;86(1):35-46 |
1 | J:70744 Huang EJ, Liu W, Fritzsch B, Bianchi LM, Reichardt LF, Xiang M, Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons. Development. 2001 Jul;128(13):2421-32 |
1 | J:104532 Mendes SW, Henkemeyer M, Liebl DJ, Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J Neurosci. 2006 Jan 18;26(3):882-92 |
1* | J:37095 Orioli D, Henkemeyer M, Lemke G, Klein R, Pawson T, Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J. 1996 15;15(22):6035-49 |
1* | J:92062 Pratt T, Tian NM, Simpson TI, Mason JO, Price DJ, The winged helix transcription factor Foxg1 facilitates retinal ganglion cell axon crossing of the ventral midline in the mouse. Development. 2004 Aug;131(15):3773-84 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
1* | J:233757 Treffy RW, Collins D, Hoshino N, Ton S, Katsevman GA, Oleksiak M, Runge EM, Cho D, Russo M, Spec A, Gomulka J, Henkemeyer M, Rochlin MW, Ephrin-B/EphB Signaling Is Required for Normal Innervation of Lingual Gustatory Papillae. Dev Neurosci. 2016;38(2):124-38 |
1 | J:180170 Triplett JW, Pfeiffenberger C, Yamada J, Stafford BK, Sweeney NT, Litke AM, Sher A, Koulakov AA, Feldheim DA, Competition is a driving force in topographic mapping. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19060-5 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1 | J:166759 Villasenor A, Chong DC, Henkemeyer M, Cleaver O, Epithelial dynamics of pancreatic branching morphogenesis. Development. 2010 Dec;137(24):4295-305 |
1 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
1 | J:316215 Zhou N, Li N, Liu J, Wang Y, Gao J, Wu Y, Chen X, Liu C, Xiao J, Persistent Wnt/beta-catenin signaling in mouse epithelium induces the ectopic Dspp expression in cheek mesenchyme. Organogenesis. 2019;15(1):1-12 |
Ephb3 Eph receptor B3 (Synonyms: Cek10, Etk2, HEK2, MDK5, Sek4, Tyro6) | |
Results | Reference |
1* | J:60855 Birgbauer E, Cowan CA, Sretavan DW, Henkemeyer M, Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina. Development. 2000 Mar;127(6):1231-41 |
2* | J:29979 Ciossek T, Lerch MM, Ullrich A, Cloning, characterization, and differential expression of MDK2 and MDK5, two novel receptor tyrosine kinases of the eck/eph family. Oncogene. 1995 Nov 16;11(10):2085-95 |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:104532 Mendes SW, Henkemeyer M, Liebl DJ, Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J Neurosci. 2006 Jan 18;26(3):882-92 |
2* | J:37095 Orioli D, Henkemeyer M, Lemke G, Klein R, Pawson T, Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J. 1996 15;15(22):6035-49 |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1 | J:166759 Villasenor A, Chong DC, Henkemeyer M, Cleaver O, Epithelial dynamics of pancreatic branching morphogenesis. Development. 2010 Dec;137(24):4295-305 |
1 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
Ephb4 Eph receptor B4 (Synonyms: b2b2412Clo, Htk, MDK2, Myk1, Tyro11) | |
Results | Reference |
1 | J:240790 Aghajanian H, Cho YK, Manderfield LJ, Herling MR, Gupta M, Ho VC, Li L, Degenhardt K, Aharonov A, Tzahor E, Epstein JA, Coronary vasculature patterning requires a novel endothelial ErbB2 holoreceptor. Nat Commun. 2016 Jun 30;7:12038 |
2* | J:29979 Ciossek T, Lerch MM, Ullrich A, Cloning, characterization, and differential expression of MDK2 and MDK5, two novel receptor tyrosine kinases of the eck/eph family. Oncogene. 1995 Nov 16;11(10):2085-95 |
1 | J:185218 Hall-Glenn F, De Young RA, Huang BL, van Handel B, Hofmann JJ, Chen TT, Choi A, Ong JR, Benya PD, Mikkola H, Iruela-Arispe ML, Lyons KM, CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PLoS One. 2012;7(2):e30562 |
1 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
2 | J:299728 Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL, Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. Elife. 2019 Dec 4;8:e49977 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:193198 Wu B, Zhang Z, Lui W, Chen X, Wang Y, Chamberlain AA, Moreno-Rodriguez RA, Markwald RR, O'Rourke BP, Sharp DJ, Zheng D, Lenz J, Baldwin HS, Chang CP, Zhou B, Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling. Cell. 2012 Nov 21;151(5):1083-96 |
1* | J:231672 Xavier GM, Miletich I, Cobourne MT, Ephrin Ligands and Eph Receptors Show Regionally Restricted Expression in the Developing Palate and Tongue. Front Physiol. 2016;7:60 |
Ephb6 Eph receptor B6 (Synonyms: Cekl, Mep) | |
Results | Reference |
1 | J:70744 Huang EJ, Liu W, Fritzsch B, Bianchi LM, Reichardt LF, Xiang M, Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons. Development. 2001 Jul;128(13):2421-32 |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
1* | J:79747 Shimoyama M, Matsuoka H, Nagata A, Iwata N, Tamekane A, Okamura A, Gomyo H, Ito M, Jishage K, Kamada N, Suzuki H, Tetsuo Noda T, Matsui T, Developmental expression of EphB6 in the thymus: lessons from EphB6 knockout mice. Biochem Biophys Res Commun. 2002 Oct 18;298(1):87 |
1* | J:105961 van Eyll JM, Passante L, Pierreux CE, Lemaigre FP, Vanderhaeghen P, Rousseau GG, Eph receptors and their ephrin ligands are expressed in developing mouse pancreas. Gene Expr Patterns. 2006 Apr;6(4):353-9 |
Epo erythropoietin | |
Results | Reference |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
1 | J:222261 Tan KS, Inoue T, Kulkeaw K, Tanaka Y, Lai MI, Sugiyama D, Localized SCF and IGF-1 secretion enhances erythropoiesis in the spleen of murine embryos. Biol Open. 2015;4(5):596-607 |
1* | J:285404 Ueda T, Yokota T, Okuzaki D, Uno Y, Mashimo T, Kubota Y, Sudo T, Ishibashi T, Shingai Y, Doi Y, Ozawa T, Nakai R, Tanimura A, Ichii M, Ezoe S, Shibayama H, Oritani K, Kanakura Y, Endothelial Cell-Selective Adhesion Molecule Contributes to the Development of Definitive Hematopoiesis in the Fetal Liver. Stem Cell Reports. 2019 Dec 10;13(6):992-1005 |
1* | J:39822 Zimmermann F, Rich IN, Mammalian homeobox B6 expression can be correlated with erythropoietin production sites and erythropoiesis during development, but not with hematopoietic or nonhematopoietic stem cell populations. Blood. 1997 Apr 15;89(8):2723-35 |
Epor erythropoietin receptor | |
Results | Reference |
1* | J:358134 Soma S, Murakami K, Fukuchi Y, Kunimoto H, Nakajima H, O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. Stem Cells. 2024 Jan 13;42(1):55-63 |
1* | J:285404 Ueda T, Yokota T, Okuzaki D, Uno Y, Mashimo T, Kubota Y, Sudo T, Ishibashi T, Shingai Y, Doi Y, Ozawa T, Nakai R, Tanimura A, Ichii M, Ezoe S, Shibayama H, Oritani K, Kanakura Y, Endothelial Cell-Selective Adhesion Molecule Contributes to the Development of Definitive Hematopoiesis in the Fetal Liver. Stem Cell Reports. 2019 Dec 10;13(6):992-1005 |
3* | J:216780 Zafiriou MP, Noack C, Unsold B, Didie M, Pavlova E, Fischer HJ, Reichardt HM, Bergmann MW, El-Armouche A, Zimmermann WH, Zelarayan LC, Erythropoietin responsive cardiomyogenic cells contribute to heart repair post myocardial infarction. Stem Cells. 2014 Sep;32(9):2480-91 |
Eppk1 epiplakin 1 (Synonyms: EPIPL1, EPPK) | |
Results | Reference |
1* | J:170660 Matsuo A, Yoshida T, Yasukawa T, Miki R, Kume K, Kume S, Epiplakin1 is expressed in the cholangiocyte lineage cells in normal liver and adult progenitor cells in injured liver. Gene Expr Patterns. 2011 Mar-Apr;11(3-4):255-62 |
Eps8 epidermal growth factor receptor pathway substrate 8 | |
Results | Reference |
1* | J:90061 Offenhauser N, Borgonovo A, Disanza A, Romano P, Ponzanelli I, Iannolo G, Di Fiore PP, Scita G, The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway. Mol Biol Cell. 2004 Jan;15(1):91-8 |
1 | J:271898 Tadenev ALD, Akturk A, Devanney N, Mathur PD, Clark AM, Yang J, Tarchini B, GPSM2-GNAI Specifies the Tallest Stereocilia and Defines Hair Bundle Row Identity. Curr Biol. 2019 Feb 19; |
Eps8l1 EPS8-like 1 (Synonyms: 2310051G19Rik, 4632407K17Rik, DRC3, EPS8R1) | |
Results | Reference |
1* | J:90061 Offenhauser N, Borgonovo A, Disanza A, Romano P, Ponzanelli I, Iannolo G, Di Fiore PP, Scita G, The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway. Mol Biol Cell. 2004 Jan;15(1):91-8 |
Eps8l2 EPS8-like 2 | |
Results | Reference |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1* | J:90061 Offenhauser N, Borgonovo A, Disanza A, Romano P, Ponzanelli I, Iannolo G, Di Fiore PP, Scita G, The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway. Mol Biol Cell. 2004 Jan;15(1):91-8 |
Eps8l3 EPS8-like 3 | |
Results | Reference |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1* | J:90061 Offenhauser N, Borgonovo A, Disanza A, Romano P, Ponzanelli I, Iannolo G, Di Fiore PP, Scita G, The eps8 family of proteins links growth factor stimulation to actin reorganization generating functional redundancy in the Ras/Rac pathway. Mol Biol Cell. 2004 Jan;15(1):91-8 |
Epyc epiphycan (Synonyms: Dspg3, epiphycan, PG-Lb, SLRR3B) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Erbb2 erb-b2 receptor tyrosine kinase 2 (Synonyms: c-erbB2, c-neu, ErbB-2, HER-2, HER2, l11Jus8, mKIAA3023, Neu, Neu oncogene) | |
Results | Reference |
1 | J:179734 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS, Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Dev Dyn. 2012 Feb;241(2):303-14 |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1 | J:147689 Fisher MC, Clinton GM, Maihle NJ, Dealy CN, Requirement for ErbB2/ErbB signaling in developing cartilage and bone. Dev Growth Differ. 2007 Aug;49(6):503-13 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
1 | J:99502 Jimenez-Farfan D, Guevara J, Zenteno E, Malagon H, Hernandez-Guerrero JC, EGF-R and erbB-2 in murine tooth development after ethanol exposure. Birth Defects Res A Clin Mol Teratol. 2005 Feb;73(2):65-71 |
1 | J:102070 Liu J, Nethery D, Kern JA, Neuregulin-1 induces branching morphogenesis in the developing lung through a P13K signal pathway. Exp Lung Res. 2004 Sep;30(6):465-78 |
1 | J:187102 Ortega MC, Bribian A, Peregrin S, Gil MT, Marin O, de Castro F, Neuregulin-1/ErbB4 signaling controls the migration of oligodendrocyte precursor cells during development. Exp Neurol. 2012 Jun;235(2):610-20 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:74258 Stolt CC, Rehberg S, Ader M, Lommes P, Riethmacher D, Schachner M, Bartsch U, Wegner M, Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev. 2002 Jan 15;16(2):165-70 |
1* | J:335824 Xu Z, Gao Z, Fu H, Zeng Y, Jin Y, Xu B, Zhang Y, Pan Z, Chen X, Zhang X, Wang X, Yan H, Yang X, Yang B, He Q, Luo P, PTX3 from vascular endothelial cells contributes to trastuzumab-induced cardiac complications. Cardiovasc Res. 2023 May 22;119(5):1250-1264 |
Erbb3 erb-b2 receptor tyrosine kinase 3 (Synonyms: Erbb-3, Erbb3r, HER3) | |
Results | Reference |
1 | J:179734 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS, Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Dev Dyn. 2012 Feb;241(2):303-14 |
1 | J:102070 Liu J, Nethery D, Kern JA, Neuregulin-1 induces branching morphogenesis in the developing lung through a P13K signal pathway. Exp Lung Res. 2004 Sep;30(6):465-78 |
1 | J:187102 Ortega MC, Bribian A, Peregrin S, Gil MT, Marin O, de Castro F, Neuregulin-1/ErbB4 signaling controls the migration of oligodendrocyte precursor cells during development. Exp Neurol. 2012 Jun;235(2):610-20 |
1 | J:356085 Wang J, Tian GG, Zheng Z, Li B, Xing Q, Wu J, Comprehensive Transcriptomic Analysis of Mouse Gonadal Development Involving Sexual Differentiation, Meiosis and Gametogenesis. Biol Proced Online. 2019;21:20 |
Erbb4 erb-b2 receptor tyrosine kinase 4 (Synonyms: ErbB4, Her4) | |
Results | Reference |
1 | J:84095 Bao J, Wolpowitz D, Role LW, Talmage DA, Back signaling by the Nrg-1 intracellular domain. J Cell Biol. 2003 Jun 23;161(6):1133-41 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:126582 Cobos I, Borello U, Rubenstein JL, Dlx transcription factors promote migration through repression of axon and dendrite growth. Neuron. 2007 Jun 21;54(6):873-88 |
1 | J:179734 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS, Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Dev Dyn. 2012 Feb;241(2):303-14 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1* | J:80421 Huotari MA, Miettinen PJ, Palgi J, Koivisto T, Ustinov J, Harari D, Yarden Y, Otonkoski T, ErbB signaling regulates lineage determination of developing pancreatic islet cells in embryonic organ culture. Endocrinology. 2002 Nov;143(11):4437-46 |
1 | J:256526 Kuerbitz J, Arnett M, Ehrman S, Williams MT, Vorhees CV, Fisher SE, Garratt AN, Muglia LJ, Waclaw RR, Campbell K, Loss of Intercalated Cells (ITCs) in the Mouse Amygdala of Tshz1 Mutants Correlates with Fear, Depression, and Social Interaction Phenotypes. J Neurosci. 2018 Jan 31;38(5):1160-1177 |
1 | J:246806 Li Y, Zhang L, Hu Y, Chen M, Han F, Qin Y, Chen M, Cui X, Duo S, Tang F, Gao F, beta-Catenin directs the transformation of testis Sertoli cells to ovarian granulosa-like cells by inducing Foxl2 expression. J Biol Chem. 2017 Oct 27;292(43):17577-17586 |
1 | J:102070 Liu J, Nethery D, Kern JA, Neuregulin-1 induces branching morphogenesis in the developing lung through a P13K signal pathway. Exp Lung Res. 2004 Sep;30(6):465-78 |
4 | J:187102 Ortega MC, Bribian A, Peregrin S, Gil MT, Marin O, de Castro F, Neuregulin-1/ErbB4 signaling controls the migration of oligodendrocyte precursor cells during development. Exp Neurol. 2012 Jun;235(2):610-20 |
1 | J:197638 van den Berghe V, Stappers E, Vandesande B, Dimidschstein J, Kroes R, Francis A, Conidi A, Lesage F, Dries R, Cazzola S, Berx G, Kessaris N, Vanderhaeghen P, van Ijcken W, Grosveld FG, Goossens S, Haigh JJ, Fishell G, Goffinet A, Aerts S, Huylebroeck D, Seuntjens E, Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1. Neuron. 2013 Jan 9;77(1):70-82 |
2 | J:180153 Veikkolainen V, Naillat F, Railo A, Chi L, Manninen A, Hohenstein P, Hastie N, Vainio S, Elenius K, ErbB4 Modulates Tubular Cell Polarity and Lumen Diameter during Kidney Development. J Am Soc Nephrol. 2012 Jan;23(1):112-22 |
1 | J:356085 Wang J, Tian GG, Zheng Z, Li B, Xing Q, Wu J, Comprehensive Transcriptomic Analysis of Mouse Gonadal Development Involving Sexual Differentiation, Meiosis and Gametogenesis. Biol Proced Online. 2019;21:20 |
Erc2 ELKS/RAB6-interacting/CAST family member 2 (Synonyms: CAST, D14Ertd171e, ELKS2alpha) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1* | J:281311 Nakano Y, Wiechert S, Banfi B, Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8 |
1 | J:331893 Yang J, Zhang L, Li Y, Chen M, Identifying key m(6)A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses. Front Genet. 2022;13:974357 |
Ercc3 excision repair cross-complementing rodent repair deficiency, complementation group 3 (Synonyms: XPB) | |
Results | Reference |
1* | J:301228 Laugel-Haushalter V, Langer A, Marrie J, Fraulob V, Schuhbaur B, Koch-Phillips M, Dolle P, Bloch-Zupan A, From the transcription of genes involved in ectodermal dysplasias to the understanding of associated dental anomalies. Mol Syndromol. 2012 Oct;3(4):158-68 |
Ereg epiregulin (Synonyms: EPR) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:130339 Minami S, Iwamoto R, Mekada E, HB-EGF decelerates cell proliferation synergistically with TGFalpha in perinatal distal lung development. Dev Dyn. 2008 Jan;237(1):247-58 |
Erg ETS transcription factor (Synonyms: D030036I24Rik) | |
Results | Reference |
1 | J:217615 Chen HI, Poduri A, Numi H, Kivela R, Saharinen P, McKay AS, Raftrey B, Churko J, Tian X, Zhou B, Wu JC, Alitalo K, Red-Horse K, VEGF-C and aortic cardiomyocytes guide coronary artery stem development. J Clin Invest. 2014 Nov;124(11):4899-914 |
1 | J:160493 Dy P, Smits P, Silvester A, Penzo-Mendez A, Dumitriu B, Han Y, de la Motte CA, Kingsley DM, Lefebvre V, Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. Dev Biol. 2010 May 15;341(2):346-59 |
1 | J:264149 Goto S, Onishi A, Misaki K, Yonemura S, Sugita S, Ito H, Ohigashi Y, Ema M, Sakaguchi H, Nishida K, Takahashi M, Neural retina-specific Aldh1a1 controls dorsal choroidal vascular development via Sox9 expression in retinal pigment epithelial cells. Elife. 2018 Apr 3;7:e32358 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
1 | J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132 |
1 | J:297253 Vila Ellis L, Cain MP, Hutchison V, Flodby P, Crandall ED, Borok Z, Zhou B, Ostrin EJ, Wythe JD, Chen J, Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung. Dev Cell. 2020 Mar 9;52(5):617-630.e6 |
1 | J:306543 Yu Z, Zeng J, Wang J, Cui Y, Song X, Zhang Y, Cheng X, Hou N, Teng Y, Lan Y, Chen Y, Yang X, Hepatocyte growth factor-regulated tyrosine kinase substrate is essential for endothelial cell polarity and cerebrovascular stability. Cardiovasc Res. 2021 Jan 21;117(2):533-546 |
Ergic3 ERGIC and golgi 3 (Synonyms: 2310015B14Rik, CGI-54, D2Ucla1, NY-BR-84, Sdbcag84) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Ern1 endoplasmic reticulum to nucleus signalling 1 (Synonyms: 9030414B18Rik, Ire1a, Ire1alpha, Ire1p) | |
Results | Reference |
2* | J:294896 Aryal YP, Lee ES, Kim TY, Sung S, Kim JY, An SY, Jung JK, Ha JH, Suh JY, Yamamoto H, Sohn WJ, Cho SW, Lee Y, An CH, Kim JY, Stage-specific expression patterns of ER stress-related molecules in mice molars: Implications for tooth development. Gene Expr Patterns. 2020 Sep;37:119130 |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
Ero1a endoplasmic reticulum oxidoreductase 1 alpha (Synonyms: Ero1l) | |
Results | Reference |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
Errfi1 ERBB receptor feedback inhibitor 1 (Synonyms: 1300002F13Rik, Mig-6, RALT) | |
Results | Reference |
1* | J:153715 Jin N, Cho SN, Raso MG, Wistuba I, Smith Y, Yang Y, Kurie JM, Yen R, Evans CM, Ludwig T, Jeong JW, DeMayo FJ, Mig-6 is required for appropriate lung development and to ensure normal adult lung homeostasis. Development. 2009 Oct;136(19):3347-56 |
Esm1 endothelial cell-specific molecule 1 (Synonyms: 0610042H23Rik) | |
Results | Reference |
1* | J:305967 Abid MR, Yi X, Yano K, Shih SC, Aird WC, Vascular endocan is preferentially expressed in tumor endothelium. Microvasc Res. 2006 Nov;72(3):136-45 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
Esr1 estrogen receptor 1 (alpha) (Synonyms: ER[a], ERa, ER-alpha, ERalpha, ESR, Estr, Estra, Nr3a1) | |
Results | Reference |
1* | J:141806 Barle EL, Pogacnik A, Zabavnik J, Expression of oestrogen receptor alpha during development of the skeleton in mice fetuses: immunohistochemical study. Anat Histol Embryol. 2008 Dec;37(6):408-14 |
1* | J:85725 Beyer C, Kuppers E, Karolczak M, Trotter A, Ontogenetic expression of estrogen and progesterone receptors in the mouse lung. Biol Neonate. 2003;84(1):59-63 |
1 | J:124101 Fan X, Kim HJ, Warner M, Gustafsson JA, Estrogen receptor beta is essential for sprouting of nociceptive primary afferents and for morphogenesis and maintenance of the dorsal horn interneurons. Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13696-701 |
1 | J:207602 Kumar D, Freese M, Drexler D, Hermans-Borgmeyer I, Marquardt A, Boehm U, Murine arcuate nucleus kisspeptin neurons communicate with GnRH neurons in utero. J Neurosci. 2014 Mar 5;34(10):3756-66 |
1 | J:226927 Kumar D, Periasamy V, Freese M, Voigt A, Boehm U, In Utero Development of Kisspeptin/GnRH Neural Circuitry in Male Mice. Endocrinology. 2015 Sep;156(9):3084-90 |
1* | J:54203 Lemmen JG, Broekhof JL, Kuiper GG, Gustafsson JA, van der Saag PT, van der Burg B, Expression of estrogen receptor alpha and beta during mouse embryogenesis. Mech Dev. 1999 Mar;81(1-2):163-7 |
2 | J:86854 Moe-Behrens GH, Klinger FG, Eskild W, Grotmol T, Haugen TB, De Felici M, Akt/PTEN Signaling Mediates Estrogen-Dependent Proliferation of Primordial Germ Cells in Vitro. Mol Endocrinol. 2003 Dec;17(12):2630-8 |
1 | J:361601 Park CJ, Oh JE, Lin P, Zhou S, Bunnell M, Bikorimana E, Spinella MJ, Lim HJ, Ko CJ, A Dynamic Shift in Estrogen Receptor Expression During Granulosa Cell Differentiation in the Ovary. Endocrinology. 2025 Jan 6;166(2) |
1* | J:333014 Wartenberg P, Farkas I, Csillag V, Colledge WH, Hrabovszky E, Boehm U, Sexually Dimorphic Neurosteroid Synthesis Regulates Neuronal Activity in the Murine Brain. J Neurosci. 2021 Nov 3;41(44):9177-9191 |
1* | J:3341 Wu TC, Wang L, Wan YJ, Expression of estrogen receptor gene in mouse oocyte and during embryogenesis. Mol Reprod Dev. 1992 Dec;33(4):407-12 |
1* | J:176585 Zheng Z, Cohn MJ, Developmental basis of sexually dimorphic digit ratios. Proc Natl Acad Sci U S A. 2011 Sep 27;108(39):16289-94 |
1 | J:156703 Zhou B, von Gise A, Ma Q, Hu YW, Pu WT, Genetic fate mapping demonstrates contribution of epicardium-derived cells to the annulus fibrosis of the mammalian heart. Dev Biol. 2010 Feb 15;338(2):251-61 |
Esr2 estrogen receptor 2 (beta) (Synonyms: ER beta, ERbeta, Estrb, oestrogen receptor beta) | |
Results | Reference |
1* | J:85725 Beyer C, Kuppers E, Karolczak M, Trotter A, Ontogenetic expression of estrogen and progesterone receptors in the mouse lung. Biol Neonate. 2003;84(1):59-63 |
1 | J:124101 Fan X, Kim HJ, Warner M, Gustafsson JA, Estrogen receptor beta is essential for sprouting of nociceptive primary afferents and for morphogenesis and maintenance of the dorsal horn interneurons. Proc Natl Acad Sci U S A. 2007 Aug 21;104(34):13696-701 |
1* | J:118243 Fan X, Warner M, Gustafsson JA, Estrogen receptor beta expression in the embryonic brain regulates development of calretinin-immunoreactive GABAergic interneurons. Proc Natl Acad Sci U S A. 2006 Dec 19;103(51):19338-43 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1* | J:54203 Lemmen JG, Broekhof JL, Kuiper GG, Gustafsson JA, van der Saag PT, van der Burg B, Expression of estrogen receptor alpha and beta during mouse embryogenesis. Mech Dev. 1999 Mar;81(1-2):163-7 |
1 | J:361601 Park CJ, Oh JE, Lin P, Zhou S, Bunnell M, Bikorimana E, Spinella MJ, Lim HJ, Ko CJ, A Dynamic Shift in Estrogen Receptor Expression During Granulosa Cell Differentiation in the Ovary. Endocrinology. 2025 Jan 6;166(2) |
Esrp1 epithelial splicing regulatory protein 1 (Synonyms: 2210008M09Rik, MGC:25805, Rbm35a) | |
Results | Reference |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
Esrra estrogen related receptor, alpha (Synonyms: Err1, ERRalpha, Estrra, Nr3b1) | |
Results | Reference |
1 | J:86854 Moe-Behrens GH, Klinger FG, Eskild W, Grotmol T, Haugen TB, De Felici M, Akt/PTEN Signaling Mediates Estrogen-Dependent Proliferation of Primordial Germ Cells in Vitro. Mol Endocrinol. 2003 Dec;17(12):2630-8 |
1* | J:42858 Sladek R, Bader JA, Giguere V, The orphan nuclear receptor estrogen-related receptor alpha is a transcriptional regulator of the human medium-chain acyl coenzyme A dehydrogenase gene. Mol Cell Biol. 1997 Sep;17(9):5400-9 |
Esrrb estrogen related receptor, beta (Synonyms: Err2, ERR2, ERRb, Estrrb) | |
Results | Reference |
1* | J:139287 Collin RW, Kalay E, Tariq M, Peters T, van der Zwaag B, Venselaar H, Oostrik J, Lee K, Ahmed ZM, Caylan R, Li Y, Spierenburg HA, Eyupoglu E, Heister A, Riazuddin S, Bahat E, Ansar M, Arslan S, Wollnik B, Brunner HG, Cremers CW, Karaguzel A, Ahmad W, Cremers FP, Vriend G, Friedman TB, Riazuddin S, Leal SM, Kremer H, Mutations of ESRRB encoding estrogen-related receptor beta cause autosomal-recessive nonsyndromic hearing impairment DFNB35. Am J Hum Genet. 2008 Jan;82(1):125-38 |
2* | J:89092 Mitsunaga K, Araki K, Mizusaki H, Morohashi K, Haruna K, Nakagata N, Giguere V, Yamamura K, Abe K, Loss of PGC-specific expression of the orphan nuclear receptor ERR-beta results in reduction of germ cell number in mouse embryos. Mech Dev. 2004 Mar;121(3):237-46 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1* | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Esrrg estrogen-related receptor gamma (Synonyms: ERR3, Errg, estrogen-related receptor 3, mKIAA0832, NR3B3) | |
Results | Reference |
1* | J:168796 Berry R, Harewood L, Pei L, Fisher M, Brownstein D, Ross A, Alaynick WA, Moss J, Hastie ND, Hohenstein P, Davies JA, Evans RM, Fitzpatrick DR, Esrrg functions in early branch generation of the ureteric bud and is essential for normal development of the renal papilla. Hum Mol Genet. 2011 Mar 1;20(5):917-26 |
1* | J:65399 Hermans-Borgmeyer I, Susens U, Borgmeyer U, Developmental expression of the estrogen receptor-related receptor gamma in the nervous system during mouse embryogenesis. Mech Dev. 2000 Oct;97(1-2):197-9 |
Esx1 extraembryonic, spermatogenesis, homeobox 1 (Synonyms: Spx1) | |
Results | Reference |
1 | J:180242 Dupressoir A, Vernochet C, Harper F, Guegan J, Dessen P, Pierron G, Heidmann T, A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1164-73 |
Ets1 E26 avian leukemia oncogene 1, 5' domain (Synonyms: Ets-1, MGC:18571, p42Ets-1, p51Ets-1, Tpl1, vs) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
1 | J:18770 Maroulakou IG, Papas TS, Green JE, Differential expression of ets-1 and ets-2 proto-oncogenes during murine embryogenesis. Oncogene. 1994 Jun;9(6):1551-65 |
1* | J:303715 Woodruff ED, Gutierrez GC, Van Otterloo E, Williams T, Cohn MJ, Anomalous incisor morphology indicates tissue-specific roles for Tfap2a and Tfap2b in tooth development. Dev Biol. 2021 Apr;472:67-74 |
Ets2 E26 avian leukemia oncogene 2, 3' domain (Synonyms: Ets-2) | |
Results | Reference |
1 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
1 | J:18770 Maroulakou IG, Papas TS, Green JE, Differential expression of ets-1 and ets-2 proto-oncogenes during murine embryogenesis. Oncogene. 1994 Jun;9(6):1551-65 |
1 | J:161774 Wang S, Turner EE, Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity. J Neurosci. 2010 Jul 7;30(27):9224-7 |
1* | J:354443 Zhang B, Zhu Y, Zhang Z, Wu F, Ma X, Sheng W, Dai R, Guo Z, Yan W, Hao L, Huang G, Ma D, Hao B, Ma J, SMC3 contributes to heart development by regulating super-enhancer associated genes. Exp Mol Med. 2024 Aug;56(8):1826-1842 |
Etv1 ets variant 1 (Synonyms: ER81, Etsrp81) | |
Results | Reference |
1* | J:130196 Alfonsi F, Filippi P, Salaun D, deLapeyriere O, Durbec P, LIFR beta plays a major role in neuronal identity determination and glial differentiation in the mouse facial nucleus. Dev Biol. 2008 Jan 1;313(1):267-78 |
1 | J:78232 Arber S, Ladle DR, Lin JH, Frank E, Jessell TM, ETS gene Er81 controls the formation of functional connections between group Ia sensory afferents and motor neurons. Cell. 2000 May 26;101(5):485-98 |
1 | J:309450 Doeppner TR, Herz J, Bahr M, Tonchev AB, Stoykova A, Zbtb20 Regulates Developmental Neurogenesis in the Olfactory Bulb and Gliogenesis After Adult Brain Injury. Mol Neurobiol. 2019 Jan;56(1):567-582 |
1 | J:160656 Eng SR, Dykes IM, Lanier J, Fedtsova N, Turner EE, POU-domain factor Brn3a regulates both distinct and common programs of gene expression in the spinal and trigeminal sensory ganglia. Neural Dev. 2007;2:3 |
1 | J:235934 Fleming MS, Li JJ, Ramos D, Li T, Talmage DA, Abe SI, Arber S, Luo W, A RET-ER81-NRG1 Signaling Pathway Drives the Development of Pacinian Corpuscles. J Neurosci. 2016 Oct 5;36(40):10337-10355 |
1 | J:355142 Gomez-Del Arco P, Isern J, Jimenez-Carretero D, Lopez-Maderuelo D, Pineiro-Sabaris R, El Abdellaoui-Soussi F, Torroja C, Vera-Pedrosa ML, Grima-Terren M, Benguria A, Simon-Chica A, Queiro-Palou A, Dopazo A, Sanchez-Cabo F, Jalife J, de la Pompa JL, Filgueiras-Rama D, Munoz-Canoves P, Redondo JM, The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development. Nat Commun. 2024 Oct 4;15(1):8602 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:87404 Hanashima C, Li SC, Shen L, Lai E, Fishell G, Foxg1 suppresses early cortical cell fate. Science. 2004 Jan 2;303(5654):56-9 |
2 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1 | J:216228 Inoue S, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y, New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet. 2014 Dec 15;23(24):6553-66 |
1* | J:166980 Ishikawa T, Gotoh N, Murayama C, Abe T, Iwashita M, Matsuzaki F, Suzuki T, Yamamoto T, IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons. Dev Dyn. 2011 Jan;240(1):96-107 |
1 | J:293331 Martinez-Chavez E, Scheerer C, Wizenmann A, Blaess S, The zinc-finger transcription factor GLI3 is a regulator of precerebellar neuronal migration. Development. 2018 Dec 17;145(24):dev166033 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
2 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1* | J:107207 Sedy J, Tseng S, Walro JM, Grim M, Kucera J, ETS transcription factor ER81 is required for the Pacinian corpuscle development. Dev Dyn. 2006 Apr;235(4):1081-9 |
1 | J:239700 Shekhar A, Lin X, Liu FY, Zhang J, Mo H, Bastarache L, Denny JC, Cox NJ, Delmar M, Roden DM, Fishman GI, Park DS, Transcription factor ETV1 is essential for rapid conduction in the heart. J Clin Invest. 2016 Dec 01;126(12):4444-4459 |
1* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
3 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1 | J:150808 Tuoc TC, Radyushkin K, Tonchev AB, Pinon MC, Ashery-Padan R, Molnar Z, Davidoff MS, Stoykova A, Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice. J Neurosci. 2009 Jul 1;29(26):8335-49 |
1 | J:107576 Waclaw RR, Allen ZJ 2nd, Bell SM, Erdelyi F, Szabo G, Potter SS, Campbell K, The zinc finger transcription factor Sp8 regulates the generation and diversity of olfactory bulb interneurons. Neuron. 2006 Feb 16;49(4):503-16 |
1 | J:161774 Wang S, Turner EE, Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity. J Neurosci. 2010 Jul 7;30(27):9224-7 |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
1 | J:184434 Xiang C, Baubet V, Pal S, Holderbaum L, Tatard V, Jiang P, Davuluri RV, Dahmane N, RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion. Cell Death Differ. 2012 Apr;19(4):692-702 |
Etv4 ets variant 4 (Synonyms: Pea-3, Pea3) | |
Results | Reference |
1 | J:99702 Albert Y, Whitehead J, Eldredge L, Carter J, Gao X, Tourtellotte WG, Transcriptional regulation of myotube fate specification and intrafusal muscle fiber morphogenesis. J Cell Biol. 2005 Apr 25;169(2):257-68 |
1 | J:78232 Arber S, Ladle DR, Lin JH, Frank E, Jessell TM, ETS gene Er81 controls the formation of functional connections between group Ia sensory afferents and motor neurons. Cell. 2000 May 26;101(5):485-98 |
1 | J:197913 de Nooij JC, Doobar S, Jessell TM, Etv1 inactivation reveals proprioceptor subclasses that reflect the level of NT3 expression in muscle targets. Neuron. 2013 Mar 20;77(6):1055-68 |
1 | J:259186 Heng X, Guo Q, Leung AW, Li JY, Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6:e23253 |
1 | J:80793 Hippenmeyer S, Shneider NA, Birchmeier C, Burden SJ, Jessell TM, Arber S, A role for neuregulin1 signaling in muscle spindle differentiation. Neuron. 2002 Dec 19;36(6):1035-49 |
1 | J:216228 Inoue S, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y, New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet. 2014 Dec 15;23(24):6553-66 |
1* | J:280430 Janeckova E, Feng J, Li J, Rodriguez G, Chai Y, Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development. PLoS One. 2019;14(10):e0223879 |
1 | J:130572 Klein OD, Lyons DB, Balooch G, Marshall GW, Basson MA, Peterka M, Boran T, Peterkova R, Martin GR, An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development. 2008 Jan;135(2):377-85 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1 | J:161774 Wang S, Turner EE, Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity. J Neurosci. 2010 Jul 7;30(27):9224-7 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
Etv5 ets variant 5 (Synonyms: 1110005E01Rik, 8430401F14Rik, erm) | |
Results | Reference |
1 | J:259186 Heng X, Guo Q, Leung AW, Li JY, Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6:e23253 |
1 | J:126807 Hippenmeyer S, Huber RM, Ladle DR, Murphy K, Arber S, ETS transcription factor Erm controls subsynaptic gene expression in skeletal muscles. Neuron. 2007 Sep 6;55(5):726-40 |
1 | J:80793 Hippenmeyer S, Shneider NA, Birchmeier C, Burden SJ, Jessell TM, Arber S, A role for neuregulin1 signaling in muscle spindle differentiation. Neuron. 2002 Dec 19;36(6):1035-49 |
1 | J:250152 Hu X, Tang Z, Li Y, Liu W, Zhang S, Wang B, Tian Y, Zhao Y, Ran H, Liu W, Feng GS, Shuai J, Wang H, Lu Z, Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice. Sci Rep. 2015 Aug 12;5:12982 |
1 | J:216228 Inoue S, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y, New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet. 2014 Dec 15;23(24):6553-66 |
1* | J:280430 Janeckova E, Feng J, Li J, Rodriguez G, Chai Y, Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development. PLoS One. 2019;14(10):e0223879 |
1 | J:130572 Klein OD, Lyons DB, Balooch G, Marshall GW, Basson MA, Peterka M, Boran T, Peterkova R, Martin GR, An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development. 2008 Jan;135(2):377-85 |
1 | J:218941 Meier F, Giesert F, Delic S, Faus-Kessler T, Matheus F, Simeone A, Holter SM, Kuhn R, Weisenhorn DM, Wurst W, Prakash N, FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS One. 2014;9(7):e101124 |
1 | J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
1 | J:161774 Wang S, Turner EE, Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity. J Neurosci. 2010 Jul 7;30(27):9224-7 |
1 | J:168036 Wells KL, Mou C, Headon DJ, Tucker AS, Defects and rescue of the minor salivary glands in Eda pathway mutants. Dev Biol. 2011 Jan 15;349(2):137-46 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
Eva1a eva-1 homolog A, regulator of programmed cell death (Synonyms: Fam176a, MGC:25911, MGC:37042, Tmem166) | |
Results | Reference |
3 | J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410 |
Evc EvC ciliary complex subunit 1 (Synonyms: Ellis van Creveld gene syndrome) | |
Results | Reference |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
Evc2 EvC ciliary complex subunit 2 (Synonyms: 1110017L09Rik, Ellis van Creveld syndrome 2, Lbn, limbin) | |
Results | Reference |
1* | J:316640 Badri MK, Zhang H, Ohyama Y, Venkitapathi S, Alamoudi A, Kamiya N, Takeda H, Ray M, Scott G, Tsuji T, Kunieda T, Mishina Y, Mochida Y, Expression of Evc2 in craniofacial tissues and craniofacial bone defects in Evc2 knockout mouse. Arch Oral Biol. 2016 Aug;68:142-52 |
1* | J:301228 Laugel-Haushalter V, Langer A, Marrie J, Fraulob V, Schuhbaur B, Koch-Phillips M, Dolle P, Bloch-Zupan A, From the transcription of genes involved in ectodermal dysplasias to the understanding of associated dental anomalies. Mol Syndromol. 2012 Oct;3(4):158-68 |
Evx1 even-skipped homeobox 1 (Synonyms: Evx-1) | |
Results | Reference |
2 | J:70191 Pierani A, Moran-Rivard L, Sunshine MJ, Littman DR, Goulding M, Jessell TM, Control of interneuron fate in the developing spinal cord by the progenitor homeodomain protein Dbx1. Neuron. 2001 Feb;29(2):367-84 |
1 | J:287023 Schnerwitzki D, Perry S, Ivanova A, Caixeta FV, Cramer P, Gunther S, Weber K, Tafreshiha A, Becker L, Vargas Panesso IL, Klopstock T, Hrabe de Angelis M, Schmidt M, Kullander K, Englert C, Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord. Life Sci Alliance. 2018 Aug;1(4):e201800106 |
Evx2 even-skipped homeobox 2 (Synonyms: Evx-2) | |
Results | Reference |
2 | J:70191 Pierani A, Moran-Rivard L, Sunshine MJ, Littman DR, Goulding M, Jessell TM, Control of interneuron fate in the developing spinal cord by the progenitor homeodomain protein Dbx1. Neuron. 2001 Feb;29(2):367-84 |
Ewsr1 Ewing sarcoma breakpoint region 1 (Synonyms: Ews) | |
Results | Reference |
1* | J:70044 Melot T, Dauphinot L, Sevenet N, Radvanyi F, Delattre O, Characterization of a new brain-specific isoform of the EWS oncoprotein. Eur J Biochem. 2001 Jun;268(12):3483-9 |
Exoc1 exocyst complex component 1 (Synonyms: 2810407P21Rik, A730011E05Rik, SEC3, Sec3l1, Sec3p) | |
Results | Reference |
1* | J:250161 Lee AJ, Polgar N, Napoli JA, Lui VH, Tamashiro KK, Fujimoto BA, Thompson KS, Fogelgren B, Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy. Sci Rep. 2016 Aug 11;6:31137 |
Exoc3l2 exocyst complex component 3-like 2 (Synonyms: 4933417E01Rik, Gm19857) | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
Exoc5 exocyst complex component 5 (Synonyms: PRO1912, SEC10, Sec10l1) | |
Results | Reference |
1* | J:250161 Lee AJ, Polgar N, Napoli JA, Lui VH, Tamashiro KK, Fujimoto BA, Thompson KS, Fogelgren B, Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy. Sci Rep. 2016 Aug 11;6:31137 |
Ext1 exostosin glycosyltransferase 1 | |
Results | Reference |
1 | J:42532 Lin X, Wells D, Isolation of the mouse cDNA homologous to the human EXT1 gene responsible for Hereditary Multiple Exostoses. DNA Seq. 1997;7(3-4):199-202 |
1 | J:170582 Mundy C, Yasuda T, Kinumatsu T, Yamaguchi Y, Iwamoto M, Enomoto-Iwamoto M, Koyama E, Pacifici M, Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine. Dev Biol. 2011 Mar 1;351(1):70-81 |
1* | J:63309 Stickens D, Brown D, Evans GA, EXT genes are differentially expressed in bone and cartilage during mouse embryogenesis. Dev Dyn. 2000 Jul;218(3):452-64 |
Ext2 exostosin glycosyltransferase 2 | |
Results | Reference |
1* | J:63309 Stickens D, Brown D, Evans GA, EXT genes are differentially expressed in bone and cartilage during mouse embryogenesis. Dev Dyn. 2000 Jul;218(3):452-64 |
1* | J:120114 Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY, A biphasic pattern of gene expression during mouse retina development. BMC Dev Biol. 2006;6:48 |
Extl1 exostosin-like glycosyltransferase 1 (Synonyms: D430033M16Rik) | |
Results | Reference |
1* | J:63309 Stickens D, Brown D, Evans GA, EXT genes are differentially expressed in bone and cartilage during mouse embryogenesis. Dev Dyn. 2000 Jul;218(3):452-64 |
Extl3 exostosin-like glycosyltransferase 3 (Synonyms: 2900009G18Rik) | |
Results | Reference |
1* | J:306144 Osman NM, Kagohashi Y, Udagawa J, Otani H, Alpha1,4-N-acetylglucosaminyltransferase encoding gene EXTL3 expression pattern in mouse adult and developing tissues with special attention to the pancreas. Anat Embryol (Berl). 2003 Dec;207(4-5):333-41 |
1* | J:91466 Osman NM, Naora H, Otani H, Glycosyltransferase encoding gene EXTL3 is differentially expressed in the developing and adult mouse cerebral cortex. Brain Res Dev Brain Res. 2004 Jul 19;151(1-2):111-7 |
Eya1 EYA transcriptional coactivator and phosphatase 1 (Synonyms: bor) | |
Results | Reference |
1* | J:181471 Ahmed M, Wong EY, Sun J, Xu J, Wang F, Xu PX, Eya1-six1 interaction is sufficient to induce hair cell fate in the cochlea by activating atoh1 expression in cooperation with sox2. Dev Cell. 2012 Feb 14;22(2):377-90 |
1* | J:184001 Ahmed M, Xu J, Xu PX, EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear. Development. 2012 Jun;139(11):1965-77 |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
1 | J:170236 El-Hashash AH, Al Alam D, Turcatel G, Bellusci S, Warburton D, Eyes absent 1 (Eya1) is a critical coordinator of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. Dev Biol. 2011 Feb 1;350(1):112-26 |
1 | J:51285 Kalatzis V, Sahly I, El-Amraoui A, Petit C, Eya1 expression in the developing ear and kidney: towards the understanding of the pathogenesis of Branchio-Oto-Renal (BOR) syndrome. Dev Dyn. 1998 Dec;213(4):486-99 |
1* | J:38379 Xu PX, Woo I, Her H, Beier DR, Maas RL, Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode. Development. 1997 Jan;124(1):219-31 |
1* | J:140027 Zou D, Erickson C, Kim EH, Jin D, Fritzsch B, Xu PX, Eya1 gene dosage critically affects the development of sensory epithelia in the mammalian inner ear. Hum Mol Genet. 2008 Nov 1;17(21):3340-56 |
Eya2 EYA transcriptional coactivator and phosphatase 2 | |
Results | Reference |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
2 | J:315293 Kumamoto T, Toma K, Gunadi, McKenna WL, Kasukawa T, Katzman S, Chen B, Hanashima C, Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013 Mar 28;3(3):931-45 |
1 | J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005 |
1* | J:38379 Xu PX, Woo I, Her H, Beier DR, Maas RL, Mouse Eya homologues of the Drosophila eyes absent gene require Pax6 for expression in lens and nasal placode. Development. 1997 Jan;124(1):219-31 |
1* | J:335760 Zhang T, Xu PX, The role of Eya1 and Eya2 in the taste system of mice from embryonic stage to adulthood. Front Cell Dev Biol. 2023;11:1126968 |
Ezh1 enhancer of zeste 1 polycomb repressive complex 2 subunit (Synonyms: mKIAA0388) | |
Results | Reference |
1 | J:185237 Chen L, Ma Y, Kim EY, Yu W, Schwartz RJ, Qian L, Wang J, Conditional ablation of Ezh2 in murine hearts reveals its essential roles in endocardial cushion formation, cardiomyocyte proliferation and survival. PLoS One. 2012;7(2):e31005 |
1 | J:192707 He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, Pu WT, Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res. 2012 Feb 3;110(3):406-15 |
Ezh2 enhancer of zeste 2 polycomb repressive complex 2 subunit (Synonyms: Enx-1, Enx1h, KMT6) | |
Results | Reference |
1 | J:185237 Chen L, Ma Y, Kim EY, Yu W, Schwartz RJ, Qian L, Wang J, Conditional ablation of Ezh2 in murine hearts reveals its essential roles in endocardial cushion formation, cardiomyocyte proliferation and survival. PLoS One. 2012;7(2):e31005 |
1 | J:193244 Di Meglio T, Kratochwil CF, Vilain N, Loche A, Vitobello A, Yonehara K, Hrycaj SM, Roska B, Peters AH, Eichmann A, Wellik D, Ducret S, Rijli FM, Ezh2 orchestrates topographic migration and connectivity of mouse precerebellar neurons. Science. 2013 Jan 11;339(6116):204-7 |
2 | J:220467 Galvis LA, Holik AZ, Short KM, Pasquet J, Lun AT, Blewitt ME, Smyth IM, Ritchie ME, Asselin-Labat ML, Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung. Development. 2015 Apr 15;142(8):1458-69 |
1 | J:346895 Guo P, Lim RC, Rajawasam K, Trinh T, Sun H, Zhang H, A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis. Elife. 2024 Feb 12;13 |
1 | J:192707 He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, Pu WT, Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res. 2012 Feb 3;110(3):406-15 |
1* | J:179371 He A, Shen X, Ma Q, Cao J, von Gise A, Zhou P, Wang G, Marquez VE, Orkin SH, Pu WT, PRC2 directly methylates GATA4 and represses its transcriptional activity. Genes Dev. 2012 Jan 1;26(1):37-42 |
2* | J:32835 Hobert O, Sures I, Ciossek T, Fuchs M, Ullrich A, Isolation and developmental expression analysis of Enx-1, a novel mouse Polycomb group gene. Mech Dev. 1996 Apr;55(2):171-84 |
1 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1* | J:174145 Ningxia Z, Shuyan L, Zhongjing S, Ling C, Tianzhong M, Lifeng W, Yan Y, Leili L, Xiancai C, Haibin C, The expression pattern of polycomb group protein ezh2 during mouse embryogenesis. Anat Rec (Hoboken). 2011 Jul;294(7):1150-7 |
3 | J:252201 Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A, p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct;137(10):2157-2167 |
1* | J:353281 Rybiczka-Tesulov M, Garritsen O, Veno MT, Wieg L, Dijk RV, Rahimi K, Gomes-Duarte A, Wit M, van de Haar LL, Michels L, van Kronenburg NCH, van der Meer C, Kjems J, Vangoor VR, Pasterkamp RJ, Circular RNAs regulate neuron size and migration of midbrain dopamine neurons during development. Nat Commun. 2024 Aug 8;15(1):6773 |
2* | J:267242 Shi X, Zhang Z, Zhan X, Cao M, Satoh T, Akira S, Shpargel K, Magnuson T, Li Q, Wang R, Wang C, Ge K, Wu J, An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth. Nat Commun. 2014 Nov 5;5:5425 |
1 | J:217677 Snitow ME, Li S, Morley MP, Rathi K, Lu MM, Kadzik RS, Stewart KM, Morrisey EE, Ezh2 represses the basal cell lineage during lung endoderm development. Development. 2015 Jan 1;142(1):108-17 |
2* | J:251843 Zhao L, Li J, Ma Y, Wang J, Pan W, Gao K, Zhang Z, Lu T, Ruan Y, Yue W, Zhao S, Wang L, Zhang D, Ezh2 is involved in radial neuronal migration through regulating Reelin expression in cerebral cortex. Sci Rep. 2015 Oct 26;5:15484 |
Ezr ezrin (Synonyms: cytovillin, ezrin, p81, Vil2) | |
Results | Reference |
1 | J:220324 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C, Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 1;142(5):871-82 |
1 | J:200722 Hick AC, Delmarcelle AS, Bouquet M, Klotz S, Copetti T, Forez C, Van Der Smissen P, Sonveaux P, Collet JF, Feron O, Courtoy PJ, Pierreux CE, Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiation. Dev Biol. 2013 Sep 1;381(1):227-40 |
1 | J:87186 Huang T, You Y, Spoor MS, Richer EJ, Kudva VV, Paige RC, Seiler MP, Liebler JM, Zabner J, Plopper CG, Brody SL, Foxj1 is required for apical localization of ezrin in airway epithelial cells. J Cell Sci. 2003 Dec 15;116(Pt 24):4935-45 |
1* | J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347 |
1 | J:237697 Maurya DK, Henriques T, Marini M, Pedemonte N, Galietta LJ, Rock JR, Harfe BD, Menini A, Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice. PLoS One. 2015;10(6):e0129171 |
1 | J:214064 Tarchini B, Jolicoeur C, Cayouette M, A molecular blueprint at the apical surface establishes planar asymmetry in cochlear hair cells. Dev Cell. 2013 Oct 14;27(1):88-102 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:346405 Vitureira N, Andres R, Perez-Martinez E, Martinez A, Bribian A, Blasi J, Chelliah S, Lopez-Domenech G, De Castro F, Burgaya F, McNagny K, Soriano E, Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation. PLoS One. 2010 Aug 10;5(8):e12003 |
F2 coagulation factor II (Synonyms: Cf-2, Cf2, FII, prothrombin, thrombin) | |
Results | Reference |
1* | J:262230 Lacombe J, Rishavy MA, Berkner KL, Ferron M, VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo. JCI Insight. 2018 Jan 11;3(1) |
1* | J:16414 Soifer SJ, Peters KG, O'Keefe J, Coughlin SR, Disparate temporal expression of the prothrombin and thrombin receptor genes during mouse development. Am J Pathol. 1994 Jan;144(1):60-9 |
F2r coagulation factor II thrombin receptor (Synonyms: Cf2r, Par1, protease-activated receptor 1, thrombin receptor, ThrR) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:16414 Soifer SJ, Peters KG, O'Keefe J, Coughlin SR, Disparate temporal expression of the prothrombin and thrombin receptor genes during mouse development. Am J Pathol. 1994 Jan;144(1):60-9 |
F2rl1 F2R like trypsin receptor 1 (Synonyms: coagulation factor II (thrombin) receptor-like 1, Gpcr11, Par2, PAR-2, Protease-activated receptor-2, proteinase-activated receptor-2) | |
Results | Reference |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
F3 coagulation factor III, tissue factor (Synonyms: CD142, Cf-3, Cf3, TF, tissue factor) | |
Results | Reference |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
1* | J:16414 Soifer SJ, Peters KG, O'Keefe J, Coughlin SR, Disparate temporal expression of the prothrombin and thrombin receptor genes during mouse development. Am J Pathol. 1994 Jan;144(1):60-9 |
F7 coagulation factor VII (Synonyms: Cf7, FVII) | |
Results | Reference |
1* | J:262230 Lacombe J, Rishavy MA, Berkner KL, Ferron M, VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo. JCI Insight. 2018 Jan 11;3(1) |
F9 coagulation factor IX (Synonyms: Cf-9, Cf9) | |
Results | Reference |
1* | J:262230 Lacombe J, Rishavy MA, Berkner KL, Ferron M, VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo. JCI Insight. 2018 Jan 11;3(1) |
F10 coagulation factor X (Synonyms: AI194738, Cf10, fX) | |
Results | Reference |
1* | J:262230 Lacombe J, Rishavy MA, Berkner KL, Ferron M, VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo. JCI Insight. 2018 Jan 11;3(1) |
F11r F11 receptor (Synonyms: BV11 antigen, ESTM33, JAM-1, JAM-A, Jcam1, Ly106) | |
Results | Reference |
1* | J:129577 Kang LI, Wang Y, Suckow AT, Czymmek KJ, Cooke VG, Naik UP, Duncan MK, Deletion of JAM-A causes morphological defects in the corneal epithelium. Int J Biochem Cell Biol. 2007;39(3):576-85 |
1 | J:112136 Sakaguchi T, Nishimoto M, Miyagi S, Iwama A, Morita Y, Iwamori N, Nakauchi H, Kiyonari H, Muramatsu M, Okuda A, Putative 'stemness' gene jam-B is not required for maintenance of stem cell state in embryonic, neural, or hematopoietic stem cells. Mol Cell Biol. 2006 Sep;26(17):6557-70 |
F730043M19Rik RIKEN cDNA F730043M19 gene | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
F930015N05Rik RIKEN cDNA F930015N05 gene | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Fa2h fatty acid 2-hydroxylase (Synonyms: Faxdc1, G630055L08Rik) | |
Results | Reference |
1* | J:175386 Maier H, Meixner M, Hartmann D, Sandhoff R, Wang-Eckhardt L, Zoller I, Gieselmann V, Eckhardt M, Normal fur development and sebum production depends on fatty acid 2-hydroxylase expression in sebaceous glands. J Biol Chem. 2011 Jul 22;286(29):25922-34 |
Fabp1 fatty acid binding protein 1, liver (Synonyms: Fabpl, L-FABP, MGC:13855) | |
Results | Reference |
1 | J:122635 Bosse T, Fialkovich JJ, Piaseckyj CM, Beuling E, Broekman H, Grand RJ, Montgomery RK, Krasinski SD, Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development. Am J Physiol Gastrointest Liver Physiol. 2007 May;292(5):G1302-14 |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
Fabp2 fatty acid binding protein 2, intestinal (Synonyms: Fabpi, Fabpi, I-FABP) | |
Results | Reference |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
Fabp4 fatty acid binding protein 4, adipocyte (Synonyms: 422/aP2, ALBP/Ap2, Ap2, Lbpl) | |
Results | Reference |
1 | J:89611 Asaki T, Konishi M, Miyake A, Kato S, Tomizawa M, Itoh N, Roles of fibroblast growth factor 10 (Fgf10) in adipogenesis in vivo. Mol Cell Endocrinol. 2004 Apr 15;218(1-2):119-28 |
2 | J:215751 Makkar A, Mishima T, Chang G, Scifres C, Sadovsky Y, Fatty acid binding protein-4 is expressed in the mouse placental labyrinth, yet is dispensable for placental triglyceride accumulation and fetal growth. Placenta. 2014 Oct;35(10):802-7 |
1 | J:107381 Nadra K, Anghel SI, Joye E, Tan NS, Basu-Modak S, Trono D, Wahli W, Desvergne B, Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta. Mol Cell Biol. 2006 Apr;26(8):3266-81 |
1 | J:269446 Salguero-Jimenez A, Grego-Bessa J, D'Amato G, Jimenez-Borreguero LJ, de la Pompa JL, Myocardial Notch1-Rbpj deletion does not affect NOTCH signaling, heart development or function. PLoS One. 2018;13(12):e0203100 |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Fabp5 fatty acid binding protein 5, epidermal (Synonyms: Fabpe E-FABP, Klbp, mal1, Unknown Klbp, keratinocyte lipid binding protein) | |
Results | Reference |
1* | J:315095 Bando Y, Yamamoto M, Sakiyama K, Inoue K, Takizawa S, Owada Y, Iseki S, Kondo H, Amano O, Expression of epidermal fatty acid binding protein (E-FABP) in septoclasts in the growth plate cartilage of mice. J Mol Histol. 2014 Oct;45(5):507-18 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:325090 Sakashita H, Bando Y, Nagasaka A, Sakiyama K, Onozawa G, Taira F, Ogasawara Y, Owada Y, Sakashita H, Amano O, Spatial and chronological localization of septoclasts in the mouse Meckel's cartilage. Histochem Cell Biol. 2022 May;157(5):569-580 |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
Fabp6 fatty acid binding protein 6 (Synonyms: gastrotropin, I-15P, I-BABP, ILBP3, Illbp) | |
Results | Reference |
1 | J:20318 Crossman MW, Hauft SM, Gordon JI, The mouse ileal lipid-binding protein gene: a model for studying axial patterning during gut morphogenesis. J Cell Biol. 1994 Sep;126(6):1547-64 |
Fabp7 fatty acid binding protein 7, brain (Synonyms: B-FABP, BFABP, Blbp) | |
Results | Reference |
1 | J:218066 Amaya DA, Wegner M, Stolt CC, Chehrehasa F, Ekberg JA, St John JA, Radial glia phagocytose axonal debris from degenerating overextending axons in the developing olfactory bulb. J Comp Neurol. 2015 Feb 1;523(2):183-96 |
1* | J:89775 Anthony TE, Klein C, Fishell G, Heintz N, Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron. 2004 Mar 25;41(6):881-90 |
1* | J:199435 Barraud P, St John JA, Stolt CC, Wegner M, Baker CV, Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Biol Open. 2013 Jul 15;2(7):750-9 |
1 | J:199451 Brunne B, Franco S, Bouche E, Herz J, Howell BW, Pahle J, Muller U, May P, Frotscher M, Bock HH, Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by reelin signaling mutant mice. Glia. 2013 Aug;61(8):1347-63 |
1 | J:167274 Brunne B, Zhao S, Derouiche A, Herz J, May P, Frotscher M, Bock HH, Origin, maturation, and astroglial transformation of secondary radial glial cells in the developing dentate gyrus. Glia. 2010 Oct;58(13):1553-69 |
1 | J:73073 Chapouton P, Schuurmans C, Guillemot F, Gotz M, The transcription factor neurogenin 2 restricts cell migration from the cortex to the striatum. Development. 2001 Dec;128(24):5149-59 |
1 | J:182705 Choe Y, Siegenthaler JA, Pleasure SJ, A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Neuron. 2012 Feb 23;73(4):698-712 |
2* | J:17847 Feng L, Hatten ME, Heintz N, Brain lipid-binding protein (BLBP): a novel signaling system in the developing mammalian CNS. Neuron. 1994 Apr;12(4):895-908 |
1 | J:62563 Gaiano N, Nye JS, Fishell G, Radial glial identity is promoted by Notch1 signaling in the murine forebrain. Neuron. 2000 May;26(2):395-404 |
1* | J:51429 Gotz M, Stoykova A, Gruss P, Pax6 controls radial glia differentiation in the cerebral cortex. Neuron. 1998 Nov;21(5):1031-44 |
1 | J:126335 Hack I, Hellwig S, Junghans D, Brunne B, Bock HH, Zhao S, Frotscher M, Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons. Development. 2007 Nov;134(21):3883-91 |
1* | J:84752 Hartfuss E, Forster E, Bock HH, Hack MA, Leprince P, Luque JM, Herz J, Frotscher M, Gotz M, Reelin signaling directly affects radial glia morphology and biochemical maturation. Development. 2003 Oct;130(19):4597-609 |
1 | J:67408 Hartfuss E, Galli R, Heins N, Gotz M, Characterization of CNS precursor subtypes and radial glia. Dev Biol. 2001 Jan 1;229(1):15-30 |
1 | J:259186 Heng X, Guo Q, Leung AW, Li JY, Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6:e23253 |
1 | J:166928 Hoeck JD, Jandke A, Blake SM, Nye E, Spencer-Dene B, Brandner S, Behrens A, Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun. Nat Neurosci. 2010 Nov;13(11):1365-72 |
1 | J:253242 Hu XL, Chen G, Zhang S, Zheng J, Wu J, Bai QR, Wang Y, Li J, Wang H, Feng H, Li J, Sun X, Xia Q, Yang F, Hang J, Qi C, Phoenix TN, Temple S, Shen Q, Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells. Neuron. 2017 Jul 19;95(2):309-325.e6 |
1 | J:173761 Hu ZL, Shi M, Huang Y, Zheng MH, Pei Z, Chen JY, Han H, Ding YQ, The role of the transcription factor Rbpj in the development of dorsal root ganglia. Neural Dev. 2011;6:14 |
1 | J:315092 Hu ZL, Zhang X, Shi M, Tian ZW, Huang Y, Chen JY, Ding YQ, Delayed but not loss of gliogenesis in Rbpj-deficient trigeminal ganglion. Int J Clin Exp Pathol. 2013;6(7):1261-71 |
1 | J:160335 Huang X, Liu J, Ketova T, Fleming JT, Grover VK, Cooper MK, Litingtung Y, Chiang C, Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8422-7 |
1* | J:283394 Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S, Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162 |
1 | J:356145 Khouri-Farah N, Guo Q, Morgan K, Shin J, Li JYH, Integrated single-cell transcriptomic and epigenetic study of cell state transition and lineage commitment in embryonic mouse cerebellum. Sci Adv. 2022 Apr;8(13):eabl9156 |
1 | J:168981 Kim JJ, Gill PS, Rotin L, van Eede M, Henkelman RM, Hui CC, Rosenblum ND, Suppressor of Fused Controls Mid-Hindbrain Patterning and Cerebellar Morphogenesis via GLI3 Repressor. J Neurosci. 2011 Feb 2;31(5):1825-36 |
1* | J:199301 Lavado A, He Y, Pare J, Neale G, Olson EN, Giovannini M, Cao X, Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34 |
1 | J:191367 Lee Y, Katyal S, Downing SM, Zhao J, Russell HR, McKinnon PJ, Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors. Nat Neurosci. 2012 Jun;15(6):819-26 |
1 | J:205567 Li K, Leung AW, Guo Q, Yang W, Li JY, Shp2-Dependent ERK Signaling Is Essential for Induction of Bergmann Glia and Foliation of the Cerebellum. J Neurosci. 2014 Jan 15;34(3):922-31 |
1 | J:136385 Li S, Jin Z, Koirala S, Bu L, Xu L, Hynes RO, Walsh CA, Corfas G, Piao X, GPR56 regulates pial basement membrane integrity and cortical lamination. J Neurosci. 2008 May 28;28(22):5817-26 |
1 | J:328234 Li Y, Fan T, Li X, Liu L, Mao F, Li Y, Miao Z, Zeng C, Song W, Pan J, Zhou S, Wang H, Wang Y, Sun ZS, Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors. Cell Rep. 2022 Aug 30;40(9):111289 |
1 | J:302828 Liu R, Yang Y, Shen J, Chen H, Zhang Q, Ba R, Wei Y, Li KC, Zhang X, Zhao C, Fstl1 is involved in the regulation of radial glial scaffold development. Mol Brain. 2015 Sep 17;8:53 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1* | J:327955 Mapps AA, Boehm E, Beier C, Keenan WT, Langel J, Liu M, Thomsen MB, Hattar S, Zhao H, Tampakakis E, Kuruvilla R, Satellite glia modulate sympathetic neuron survival, activity, and autonomic function. Elife. 2022 Aug 23;11:e74295 |
1 | J:218941 Meier F, Giesert F, Delic S, Faus-Kessler T, Matheus F, Simeone A, Holter SM, Kuhn R, Weisenhorn DM, Wurst W, Prakash N, FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS One. 2014;9(7):e101124 |
1 | J:186443 Muller Smith K, Williamson TL, Schwartz ML, Vaccarino FM, Impaired motor coordination and disrupted cerebellar architecture in Fgfr1 and Fgfr2 double knockout mice. Brain Res. 2012 Jun 15;1460:12-24 |
1 | J:182762 Mundell NA, Plank JL, LeGrone AW, Frist AY, Zhu L, Shin MK, Southard-Smith EM, Labosky PA, Enteric nervous system specific deletion of Foxd3 disrupts glial cell differentiation and activates compensatory enteric progenitors. Dev Biol. 2012 Mar 15;363(2):373-87 |
1 | J:200905 Munoz DM, Singh S, Tung T, Agnihotri S, Nagy A, Guha A, Zadeh G, Hawkins C, Differential transformation capacity of neuro-glial progenitors during development. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14378-83 |
1 | J:272073 Nicola Z, Fabel K, Kempermann G, Development of the adult neurogenic niche in the hippocampus of mice. Front Neuroanat. 2015;9:53 |
1* | J:166449 Nishino J, Saunders TL, Sagane K, Morrison SJ, Lgi4 promotes the proliferation and differentiation of glial lineage cells throughout the developing peripheral nervous system. J Neurosci. 2010 Nov 10;30(45):15228-40 |
1 | J:331057 Parichha A, Datta D, Suresh V, Chatterjee M, Holtzman MJ, Tole S, Dentate gyrus morphogenesis is regulated by beta-catenin function in hem-derived fimbrial glia. Development. 2022 Nov 1;149(21):dev200953 |
1 | J:241853 Parisot J, Flore G, Bertacchi M, Studer M, COUP-TFI mitotically regulates production and migration of dentate granule cells and modulates hippocampal Cxcr4 expression. Development. 2017 Jun 01;144(11):2045-2058 |
1 | J:255488 Premarathne S, Murtaza M, Matigian N, Jolly LA, Wood SA, Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors. Sci Rep. 2017 Aug 14;7(1):8109 |
1* | J:268254 Rich CA, Perera SN, Andratschke J, Stolt CC, Buehler DP, Southard-Smith EM, Wegner M, Britsch S, Baker CVH, Olfactory ensheathing cells abutting the embryonic olfactory bulb express Frzb, whose deletion disrupts olfactory axon targeting. Glia. 2018 Dec;66(12):2617-2631 |
1 | J:187684 Rodriguez M, Choi J, Park S, Sockanathan S, Gde2 regulates cortical neuronal identity by controlling the timing of cortical progenitor differentiation. Development. 2012 Oct;139(20):3870-9 |
1 | J:205632 Saito A, Kanemoto S, Kawasaki N, Asada R, Iwamoto H, Oki M, Miyagi H, Izumi S, Sanosaka T, Nakashima K, Imaizumi K, Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun. 2012;3:967 |
1 | J:84301 Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M, The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 2003 Jul 1;17(13):1677-89 |
1 | J:191783 Teissier A, Waclaw RR, Griveau A, Campbell K, Pierani A, Tangentially migrating transient glutamatergic neurons control neurogenesis and maintenance of cerebral cortical progenitor pools. Cereb Cortex. 2012 Feb;22(2):403-16 |
1 | J:224366 Uesaka T, Nagashimada M, Enomoto H, Neuronal Differentiation in Schwann Cell Lineage Underlies Postnatal Neurogenesis in the Enteric Nervous System. J Neurosci. 2015 Jul 8;35(27):9879-88 |
1 | J:304564 Venkataramanappa S, Schutz D, Saaber F, Kumar PA, Abe P, Schulz S, Stumm R, The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS Genet. 2021 Mar;17(3):e1009441 |
1 | J:81003 Young HM, Bergner AJ, Muller T, Acquisition of neuronal and glial markers by neural crest-derived cells in the mouse intestine. J Comp Neurol. 2003 Jan 27;456(1):1-11 |
1 | J:316159 Yu Q, Du M, Zhang W, Liu L, Gao Z, Chen W, Gu Y, Zhu K, Niu X, Sun Q, Wang L, Mesenteric Neural Crest Cells Are the Embryological Basis of Skip Segment Hirschsprung's Disease. Cell Mol Gastroenterol Hepatol. 2021;12(1):1-24 |
1 | J:287863 Zeng F, Ma X, Zhu L, Xu Q, Zeng Y, Gao Y, Li G, Guo T, Zhang H, Tang X, Wang Z, Ye Z, Zheng L, Zhang H, Zheng Q, Li K, Lu J, Qi X, Luo H, Zhang X, Wang Z, Zhou Y, Yao Y, Ke R, Zhou Y, Liu Y, Sun H, Huang T, Shao Z, Xu H, Wang X, The deubiquitinase USP6 affects memory and synaptic plasticity through modulating NMDA receptor stability. PLoS Biol. 2019 Dec;17(12):e3000525 |
2 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
Fadd Fas associated via death domain (Synonyms: Mort1/FADD) | |
Results | Reference |
1 | J:94928 De Paepe ME, Mao Q, Embree-Ku M, Rubin LP, Luks FI, Fas/FasL-mediated apoptosis in perinatal murine lungs. Am J Physiol Lung Cell Mol Physiol. 2004 Oct;287(4):L730-42 |
Fads2 fatty acid desaturase 2 (Synonyms: 2900042M13Rik, Fads2a) | |
Results | Reference |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
Fah fumarylacetoacetate hydrolase (Synonyms: swst) | |
Results | Reference |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
Fam20c FAM20C, golgi associated secretory pathway kinase (Synonyms: DMP4, MGC:7673) | |
Results | Reference |
2* | J:170017 Wang X, Hao J, Xie Y, Sun Y, Hernandez B, Yamoah AK, Prasad M, Zhu Q, Feng JQ, Qin C, Expression of FAM20C in the osteogenesis and odontogenesis of mouse. J Histochem Cytochem. 2010 Nov;58(11):957-67 |
Fam83h family with sequence similarity 83, member H | |
Results | Reference |
1* | J:156254 Lee MJ, Lee SK, Lee KE, Kang HY, Jung HS, Kim JW, Expression patterns of the Fam83h gene during murine tooth development. Arch Oral Biol. 2009 Sep;54(9):846-50 |
Fam107a family with sequence similarity 107, member A (Synonyms: DRR1) | |
Results | Reference |
1* | J:159225 Asano Y, Kishida S, Mu P, Sakamoto K, Murohara T, Kadomatsu K, DRR1 is expressed in the developing nervous system and downregulated during neuroblastoma carcinogenesis. Biochem Biophys Res Commun. 2010 Apr 9;394(3):829-35 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Fam161a family with sequence similarity 161, member A (Synonyms: 4930430E16Rik) | |
Results | Reference |
1* | J:169188 Bandah-Rozenfeld D, Mizrahi-Meissonnier L, Farhy C, Obolensky A, Chowers I, Pe'er J, Merin S, Ben-Yosef T, Ashery-Padan R, Banin E, Sharon D, Homozygosity mapping reveals null mutations in FAM161A as a cause of autosomal-recessive retinitis pigmentosa. Am J Hum Genet. 2010 Sep 10;87(3):382-91 |
Fam210b family with sequence similarity 210, member B (Synonyms: 2010011I20Rik) | |
Results | Reference |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Fam220a family with sequence similarity 220, member A (Synonyms: 1500026F15Rik, 2810453I06Rik) | |
Results | Reference |
1* | J:354403 Ren F, Su F, Ning H, Wang Y, Geng Y, Feng Y, Wang Y, Zhang Y, Jin Z, Li Y, Jia B, Chang Z, SIPAR negatively regulates STAT3 signaling and inhibits progression of melanoma. Cell Signal. 2013 Nov;25(11):2272-80 |
Fam222a family with sequence similarity 222, member A (Synonyms: BC057022) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Fanca Fanconi anemia, complementation group A | |
Results | Reference |
1 | J:56258 Abu-Issa R, Eichele G, Youssoufian H, Expression of the Fanconi anemia group A gene (Fanca) during mouse embryogenesis. Blood. 1999 Jul 15;94(2):818-24 |
1* | J:64334 Nadler JJ, Braun RE, Fanconi anemia complementation group C is required for proliferation of murine primordial germ cells [letter]. Genesis. 2000 Jul;27(3):117-23 |
Fancc Fanconi anemia, complementation group C (Synonyms: Facc) | |
Results | Reference |
1* | J:64334 Nadler JJ, Braun RE, Fanconi anemia complementation group C is required for proliferation of murine primordial germ cells [letter]. Genesis. 2000 Jul;27(3):117-23 |
Fancd2 Fanconi anemia, complementation group D2 (Synonyms: 2410150O07Rik) | |
Results | Reference |
1 | J:299451 Atkins A, Xu MJ, Li M, Rogers NP, Pryzhkova MV, Jordan PW, SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. Elife. 2020 Nov 17;9:e61171 |
Fancg Fanconi anemia, complementation group G (Synonyms: Xrcc9) | |
Results | Reference |
1* | J:64334 Nadler JJ, Braun RE, Fanconi anemia complementation group C is required for proliferation of murine primordial germ cells [letter]. Genesis. 2000 Jul;27(3):117-23 |
Far2 fatty acyl CoA reductase 2 (Synonyms: MGC:67167, Mlstd1) | |
Results | Reference |
2* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Fas Fas cell surface death receptor (Synonyms: APO-1, CD95, TNFR6, Tnfrsf6) | |
Results | Reference |
2 | J:94928 De Paepe ME, Mao Q, Embree-Ku M, Rubin LP, Luks FI, Fas/FasL-mediated apoptosis in perinatal murine lungs. Am J Physiol Lung Cell Mol Physiol. 2004 Oct;287(4):L730-42 |
1 | J:111004 Fleck M, Zhou T, Tatsuta T, Yang P, Wang Z, Mountz JD, Fas/Fas ligand signaling during gestational T cell development. J Immunol. 1998 Apr 15;160(8):3766-75 |
1 | J:32512 French LE, Hahne M, Viard I, Radlgruber G, Zanone R, Becker K, Muller C, Tschopp J, Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover. J Cell Biol. 1996 Apr;133(2):335-43 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1* | J:358134 Soma S, Murakami K, Fukuchi Y, Kunimoto H, Nakajima H, O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. Stem Cells. 2024 Jan 13;42(1):55-63 |
Fasl Fas ligand (Synonyms: APT1LG1, CD178, CD95L, Fasl, Fas-L, Tnfsf6) | |
Results | Reference |
1 | J:94928 De Paepe ME, Mao Q, Embree-Ku M, Rubin LP, Luks FI, Fas/FasL-mediated apoptosis in perinatal murine lungs. Am J Physiol Lung Cell Mol Physiol. 2004 Oct;287(4):L730-42 |
1 | J:111004 Fleck M, Zhou T, Tatsuta T, Yang P, Wang Z, Mountz JD, Fas/Fas ligand signaling during gestational T cell development. J Immunol. 1998 Apr 15;160(8):3766-75 |
2 | J:32512 French LE, Hahne M, Viard I, Radlgruber G, Zanone R, Becker K, Muller C, Tschopp J, Fas and Fas ligand in embryos and adult mice: ligand expression in several immune-privileged tissues and coexpression in adult tissues characterized by apoptotic cell turnover. J Cell Biol. 1996 Apr;133(2):335-43 |
1* | J:358134 Soma S, Murakami K, Fukuchi Y, Kunimoto H, Nakajima H, O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. Stem Cells. 2024 Jan 13;42(1):55-63 |
Fasn fatty acid synthase (Synonyms: A630082H08Rik, FAS) | |
Results | Reference |
2 | J:200565 Antony N, Weir JR, McDougall AR, Mantamadiotis T, Meikle PJ, Cole TJ, Bird AD, cAMP response element binding protein1 is essential for activation of steroyl co-enzyme a desaturase 1 (Scd1) in mouse lung type II epithelial cells. PLoS One. 2013;8(4):e59763 |
1* | J:190090 Hasegawa S, Kume H, Iinuma S, Yamasaki M, Takahashi N, Fukui T, Acetoacetyl-CoA synthetase is essential for normal neuronal development. Biochem Biophys Res Commun. 2012 Oct 19;427(2):398-403 |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
1 | J:53721 Muglia LJ, Bae DS, Brown TT, Vogt SK, Alvarez JG, Sunday ME, Majzoub JA, Proliferation and differentiation defects during lung development in corticotropin-releasing hormone-deficient mice. Am J Respir Cell Mol Biol. 1999 Feb;20(2):181-8 |
Fat1 FAT atypical cadherin 1 (Synonyms: 2310038E12Rik, Fath, mFat1) | |
Results | Reference |
1* | J:60701 Cox B, Hadjantonakis AK, Collins JE, Magee AI, Cloning and expression throughout mouse development of mfat1, a homologue of the Drosophila tumour suppressor gene fat. Dev Dyn. 2000 Mar;217(3):233-40 |
Fat3 FAT atypical cadherin 3 (Synonyms: 9430076A06Rik, D430038H04Rik, LOC234973, LOC382129) | |
Results | Reference |
1 | J:320846 Aviles EC, Krol A, Henle SJ, Burroughs-Garcia J, Deans MR, Goodrich LV, Fat3 acts through independent cytoskeletal effectors to coordinate asymmetric cell behaviors during polarized circuit assembly. Cell Rep. 2022 Feb 1;38(5):110307 |
1* | J:353281 Rybiczka-Tesulov M, Garritsen O, Veno MT, Wieg L, Dijk RV, Rahimi K, Gomes-Duarte A, Wit M, van de Haar LL, Michels L, van Kronenburg NCH, van der Meer C, Kjems J, Vangoor VR, Pasterkamp RJ, Circular RNAs regulate neuron size and migration of midbrain dopamine neurons during development. Nat Commun. 2024 Aug 8;15(1):6773 |
Fat4 FAT atypical cadherin 4 (Synonyms: 6030410K14Rik) | |
Results | Reference |
1 | J:293199 Crespo-Enriquez I, Hodgson T, Zakaria S, Cadoni E, Shah M, Allen S, Al-Khishali A, Mao Y, Yiu A, Petzold J, Villagomez-Olea G, Pitsillides AA, Irvine KD, Francis-West P, Dchs1-Fat4 regulation of osteogenic differentiation in mouse. Development. 2019 Jul 29;146(14):dev176776 |
1 | J:243807 Ragni CV, Diguet N, Le Garrec JF, Novotova M, Resende TP, Pop S, Charon N, Guillemot L, Kitasato L, Badouel C, Dufour A, Olivo-Marin JC, Trouve A, McNeill H, Meilhac SM, Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth. Nat Commun. 2017 Feb 27;8:14582 |
Fbl fibrillarin (Synonyms: RNU3IP1) | |
Results | Reference |
1 | J:160518 Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, Jenkins RB, Tihan T, Vandenberg SR, James CD, Tanaka K, Taylor MD, Weiss WA, Chesler L, Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010 May 15;24(10):1059-72 |
Fblim1 filamin binding LIM protein 1 (Synonyms: 2410043F08Rik, Cal, Fblp1, migfilin, migfilin(s)) | |
Results | Reference |
1 | J:279389 Miao Q, Hill MC, Chen F, Mo Q, Ku AT, Ramos C, Sock E, Lefebvre V, Nguyen H, SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair. Nat Commun. 2019 Sep 6;10(1):4042 |
1 | J:182886 Moik DV, Janbandhu VC, Fassler R, Loss of migfilin expression has no overt consequences on murine development and homeostasis. J Cell Sci. 2011 Feb 1;124(Pt 3):414-21 |
Fbln1 fibulin 1 | |
Results | Reference |
2 | J:179734 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS, Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Dev Dyn. 2012 Feb;241(2):303-14 |
1 | J:217906 Cooley MA, Harikrishnan K, Oppel JA, Miler SF, Barth JL, Haycraft CJ, Reddy SV, Scott Argraves W, Fibulin-1 is required for bone formation and Bmp-2-mediated induction of Osterix. Bone. 2014 Dec;69:30-8 |
1* | J:119223 Kern CB, Twal WO, Mjaatvedt CH, Fairey SE, Toole BP, Iruela-Arispe ML, Argraves WS, Proteolytic cleavage of versican during cardiac cushion morphogenesis. Dev Dyn. 2006 Aug;235(8):2238-47 |
1* | J:102464 Lee NV, Rodriguez-Manzaneque JC, Thai SN, Twal WO, Luque A, Lyons KM, Argraves WS, Iruela-Arispe ML, Fibulin-1 acts as a cofactor for the matrix metalloprotease ADAMTS-1. J Biol Chem. 2005 Oct 14;280(41):34796-804 |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
2* | J:31657 Zhang HY, Timpl R, Sasaki T, Chu ML, Ekblom P, Fibulin-1 and fibulin-2 expression during organogenesis in the developing mouse embryo. Dev Dyn. 1996 Mar;205(3):348-64 |
Fbln2 fibulin 2 (Synonyms: 5730577E14Rik) | |
Results | Reference |
1* | J:272619 Aydogdu N, Rudat C, Trowe MO, Kaiser M, Ludtke TH, Taketo MM, Christoffels VM, Moon A, Kispert A, TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827 |
1 | J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522 |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
1 | J:311811 Trowe MO, Airik R, Weiss AC, Farin HF, Foik AB, Bettenhausen E, Schuster-Gossler K, Taketo MM, Kispert A, Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter. Development. 2012 Sep;139(17):3099-108 |
1 | J:22991 Zhang HY, Chu ML, Pan TC, Sasaki T, Timpl R, Ekblom P, Extracellular matrix protein fibulin-2 is expressed in the embryonic endocardial cushion tissue and is a prominent component of valves in adult heart. Dev Biol. 1995 Jan;167(1):18-26 |
Fbln5 fibulin 5 (Synonyms: EVEC) | |
Results | Reference |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
Fbn1 fibrillin 1 (Synonyms: Fib-1) | |
Results | Reference |
2 | J:221347 Hubmacher D, Wang LW, Mecham RP, Reinhardt DP, Apte SS, Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia - a novel mouse model providing insights into geleophysic dysplasia. Dis Model Mech. 2015 May 1;8(5):487-99 |
1 | J:295274 Oichi T, Taniguchi Y, Soma K, Oshima Y, Yano F, Mori Y, Chijimatsu R, Kim-Kaneyama JR, Tanaka S, Saito T, Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway. Cell Mol Life Sci. 2019 Dec;76(23):4795-4809 |
1 | J:214897 Shi Y, Tu Y, De Maria A, Mecham RP, Bassnett S, Development, composition, and structural arrangements of the ciliary zonule of the mouse. Invest Ophthalmol Vis Sci. 2013 Apr;54(4):2504-15 |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
1* | J:160041 Tsutsui K, Manabe R, Yamada T, Nakano I, Oguri Y, Keene DR, Sengle G, Sakai LY, Sekiguchi K, ADAMTSL-6 is a novel extracellular matrix protein that binds to fibrillin-1 and promotes fibrillin-1 fibril formation. J Biol Chem. 2010 Feb 12;285(7):4870-82 |
1 | J:361964 Wang M, Liu H, Zhang M, Niu X, Sun M, Wang F, Ni Y, Hong T, Zhang W, Dang S, The secreted protease ADAMTS18 links early isoform transformation and maturation of glomerular basement membrane macromolecules to the integrity of the glomerular filtration barrier. Biochem Biophys Res Commun. 2025 Mar 1;750:151386 |
1* | J:22526 Yin W, Smiley E, Germiller J, Sanguineti C, Lawton T, Pereira L, Ramirez F, Bonadio J, Primary structure and developmental expression of Fbn-1, the mouse fibrillin gene. J Biol Chem. 1995 Jan 27;270(4):1798-806 |
1* | J:25216 Zhang H, Hu W, Ramirez F, Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils. J Cell Biol. 1995 May;129(4):1165-76 |
Fbn2 fibrillin 2 (Synonyms: Fib-2, Sne, sy) | |
Results | Reference |
2 | J:221347 Hubmacher D, Wang LW, Mecham RP, Reinhardt DP, Apte SS, Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia - a novel mouse model providing insights into geleophysic dysplasia. Dis Model Mech. 2015 May 1;8(5):487-99 |
1 | J:324217 Mead TJ, Martin DR, Wang LW, Cain SA, Gulec C, Cahill E, Mauch J, Reinhardt D, Lo C, Baldock C, Apte SS, Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development. Elife. 2022 May 3;11:e71142 |
1 | J:295274 Oichi T, Taniguchi Y, Soma K, Oshima Y, Yano F, Mori Y, Chijimatsu R, Kim-Kaneyama JR, Tanaka S, Saito T, Adamts17 is involved in skeletogenesis through modulation of BMP-Smad1/5/8 pathway. Cell Mol Life Sci. 2019 Dec;76(23):4795-4809 |
1 | J:214897 Shi Y, Tu Y, De Maria A, Mecham RP, Bassnett S, Development, composition, and structural arrangements of the ciliary zonule of the mouse. Invest Ophthalmol Vis Sci. 2013 Apr;54(4):2504-15 |
1 | J:361964 Wang M, Liu H, Zhang M, Niu X, Sun M, Wang F, Ni Y, Hong T, Zhang W, Dang S, The secreted protease ADAMTS18 links early isoform transformation and maturation of glomerular basement membrane macromolecules to the integrity of the glomerular filtration barrier. Biochem Biophys Res Commun. 2025 Mar 1;750:151386 |
2 | J:296772 Yin W, Kim HT, Wang S, Gunawan F, Li R, Buettner C, Grohmann B, Sengle G, Sinner D, Offermanns S, Stainier DYR, Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis. Eur Respir J. 2019 Mar;53(3) |
1* | J:25216 Zhang H, Hu W, Ramirez F, Developmental expression of fibrillin genes suggests heterogeneity of extracellular microfibrils. J Cell Biol. 1995 May;129(4):1165-76 |
Fbp1 fructose bisphosphatase 1 (Synonyms: Fbp-2, Fbp3, FBPase brain isoform, FBPase liver) | |
Results | Reference |
1 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
Fbxo2 F-box protein 2 (Synonyms: Fbs1, FBX2, MGC:54895, NFB42, Prpl4) | |
Results | Reference |
2 | J:266597 Hartman BH, Bscke R, Ellwanger DC, Keymeulen S, Scheibinger M, Heller S, Fbxo2(VHC) mouse and embryonic stem cell reporter lines delineate in vitro-generated inner ear sensory epithelia cells and enable otic lineage selection and Cre-recombination. Dev Biol. 2018 Nov 1;443(1):64-77 |
1 | J:355958 Hartman BH, Durruthy-Durruthy R, Laske RD, Losorelli S, Heller S, Identification and characterization of mouse otic sensory lineage genes. Front Cell Neurosci. 2015;9:79 |
Fbxo11 F-box protein 11 (Synonyms: GENA 104, Jf) | |
Results | Reference |
1* | J:114851 Hardisty-Hughes RE, Tateossian H, Morse SA, Romero MR, Middleton A, Tymowska-Lalanne Z, Hunter AJ, Cheeseman M, Brown SD, A mutation in the F-box gene, Fbxo11, causes otitis media in the Jeff mouse. Hum Mol Genet. 2006 Nov 15;15(22):3273-9 |
1 | J:156253 Tateossian H, Hardisty-Hughes RE, Morse S, Romero MR, Hilton H, Dean C, Brown SD, Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant. Pathogenetics. 2009;2(1):5 |
Fbxo32 F-box protein 32 (Synonyms: 4833442G10Rik, atrogin-1, ATROGIN1, MAFbx) | |
Results | Reference |
1 | J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97 |
Fbxo47 F-box protein 47 (Synonyms: 2900052P03Rik, LOC380724) | |
Results | Reference |
1 | J:322322 Tanno N, Takemoto K, Takada-Horisawa Y, Shimada R, Fujimura S, Tani N, Takeda N, Araki K, Ishiguro KI, FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis. iScience. 2022 Apr 15;25(4):104008 |
Fcgr1 Fc receptor, IgG, high affinity I (Synonyms: CD64, FcgammaRI) | |
Results | Reference |
1* | J:264675 Fransen MF, Benonisson H, van Maren WW, Sow HS, Breukel C, Linssen MM, Claassens JWC, Brouwers C, van der Kaa J, Camps M, Kleinovink JW, Vonk KK, van Heiningen S, Klar N, van Beek L, van Harmelen V, Daxinger L, Nandakumar KS, Holmdahl R, Coward C, Lin Q, Hirose S, Salvatori D, van Hall T, van Kooten C, Mastroeni P, Ossendorp F, Verbeek JS, A Restricted Role for FcgammaR in the Regulation of Adaptive Immunity. J Immunol. 2018 Apr 15;200(8):2615-2626 |
Fcgr2b Fc receptor, IgG, low affinity IIb (Synonyms: CD32, F630109E10Rik, Fc gamma RIIB, FcgammaRIIB, Fcgr2, Fcgr2a, Fc[g]RII, FcgRII, Fcr-2, Fcr-3, Ly-17, LyM-1, Ly-m20) | |
Results | Reference |
1* | J:264675 Fransen MF, Benonisson H, van Maren WW, Sow HS, Breukel C, Linssen MM, Claassens JWC, Brouwers C, van der Kaa J, Camps M, Kleinovink JW, Vonk KK, van Heiningen S, Klar N, van Beek L, van Harmelen V, Daxinger L, Nandakumar KS, Holmdahl R, Coward C, Lin Q, Hirose S, Salvatori D, van Hall T, van Kooten C, Mastroeni P, Ossendorp F, Verbeek JS, A Restricted Role for FcgammaR in the Regulation of Adaptive Immunity. J Immunol. 2018 Apr 15;200(8):2615-2626 |
Fcgr3 Fc receptor, IgG, low affinity III (Synonyms: CD16, FcgammaRIII, Fcg receptor III) | |
Results | Reference |
1* | J:264675 Fransen MF, Benonisson H, van Maren WW, Sow HS, Breukel C, Linssen MM, Claassens JWC, Brouwers C, van der Kaa J, Camps M, Kleinovink JW, Vonk KK, van Heiningen S, Klar N, van Beek L, van Harmelen V, Daxinger L, Nandakumar KS, Holmdahl R, Coward C, Lin Q, Hirose S, Salvatori D, van Hall T, van Kooten C, Mastroeni P, Ossendorp F, Verbeek JS, A Restricted Role for FcgammaR in the Regulation of Adaptive Immunity. J Immunol. 2018 Apr 15;200(8):2615-2626 |
Fcgr4 Fc receptor, IgG, low affinity IV (Synonyms: 4833442P21Rik, CD16-2, FcgammaRIV, Fcgr3a) | |
Results | Reference |
1* | J:264675 Fransen MF, Benonisson H, van Maren WW, Sow HS, Breukel C, Linssen MM, Claassens JWC, Brouwers C, van der Kaa J, Camps M, Kleinovink JW, Vonk KK, van Heiningen S, Klar N, van Beek L, van Harmelen V, Daxinger L, Nandakumar KS, Holmdahl R, Coward C, Lin Q, Hirose S, Salvatori D, van Hall T, van Kooten C, Mastroeni P, Ossendorp F, Verbeek JS, A Restricted Role for FcgammaR in the Regulation of Adaptive Immunity. J Immunol. 2018 Apr 15;200(8):2615-2626 |
Fcna ficolin A (Synonyms: Fcn1, ficolin A) | |
Results | Reference |
1* | J:99055 Liu Y, Endo Y, Homma S, Kanno K, Yaginuma H, Fujita T, Ficolin A and ficolin B are expressed in distinct ontogenic patterns and cell types in the mouse. Mol Immunol. 2005 Jul;42(11):1265-73 |
Fcnb ficolin B | |
Results | Reference |
1* | J:99055 Liu Y, Endo Y, Homma S, Kanno K, Yaginuma H, Fujita T, Ficolin A and ficolin B are expressed in distinct ontogenic patterns and cell types in the mouse. Mol Immunol. 2005 Jul;42(11):1265-73 |
Fcor Foxo1 corepressor (Synonyms: 2400009B08Rik, FCoR) | |
Results | Reference |
1 | J:306907 Kodani N, Nakae J, Kobayashi M, Kikuchi O, Kitamura T, Itoh H, FCoR-Foxo1 Axis Regulates alpha-Cell Mass through Repression of Arx Expression. iScience. 2020 Jan 24;23(1):100798 |
Fdps farnesyl diphosphate synthetase (Synonyms: 6030492I17Rik, Fdpsl1, mKIAA1293) | |
Results | Reference |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
Fem1b fem 1 homolog b (Synonyms: mKIAA0396) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Fen1 flap structure specific endonuclease 1 | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
Fendrr Foxf1 adjacent non-coding developmental regulatory RNA (Synonyms: 1110050K14Rik, linc-Foxf1a) | |
Results | Reference |
1* | J:283316 Garcia-Padilla C, Dominguez JN, Aranega AE, Franco D, Differential chamber-specific expression and regulation of long non-coding RNAs during cardiac development. Biochim Biophys Acta Gene Regul Mech. 2019 Oct;1862(10):194435 |
1* | J:212084 Herriges MJ, Swarr DT, Morley MP, Rathi KS, Peng T, Stewart KM, Morrisey EE, Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development. Genes Dev. 2014 Jun 15;28(12):1363-79 |
Ferd3l Fer3 like bHLH transcription factor (Synonyms: bHLHa31, fer3, Mnato3, Nato3, N-twist) | |
Results | Reference |
1* | J:78770 Verzi MP, Anderson JP, Dodou E, Kelly KK, Greene SB, North BJ, Cripps RM, Black BL, N-twist, an evolutionarily conserved bHLH protein expressed in the developing CNS, functions as a transcriptional inhibitor. Dev Biol. 2002 Sep 1;249(1):174-90 |
Fermt1 fermitin family member 1 (Synonyms: 5830467P10Rik, Kindlin-1) | |
Results | Reference |
1* | J:114381 Ussar S, Wang HV, Linder S, Fassler R, Moser M, The Kindlins: subcellular localization and expression during murine development. Exp Cell Res. 2006 Oct 1;312(16):3142-51 |
1* | J:315735 Zhan J, Yang M, Zhang J, Guo Y, Liu W, Zhang H, Kindler syndrome protein Kindlin-1 is mainly expressed in adult tissues originating from ectoderm/endoderm. Sci China Life Sci. 2015 May;58(5):432-41 |
Fermt2 fermitin family member 2 (Synonyms: Kindlin-2, Mig2, Plekhc1) | |
Results | Reference |
1* | J:114381 Ussar S, Wang HV, Linder S, Fassler R, Moser M, The Kindlins: subcellular localization and expression during murine development. Exp Cell Res. 2006 Oct 1;312(16):3142-51 |
1 | J:224370 Wu C, Jiao H, Lai Y, Zheng W, Chen K, Qu H, Deng W, Song P, Zhu K, Cao H, Galson DL, Fan J, Im HJ, Liu Y, Chen J, Chen D, Xiao G, Kindlin-2 controls TGF-beta signalling and Sox9 expression to regulate chondrogenesis. Nat Commun. 2015;6:7531 |
Fermt3 fermitin family member 3 (Synonyms: C79673, Kindlin-3, MGC:36836, MGC:38286) | |
Results | Reference |
1* | J:114381 Ussar S, Wang HV, Linder S, Fassler R, Moser M, The Kindlins: subcellular localization and expression during murine development. Exp Cell Res. 2006 Oct 1;312(16):3142-51 |
Fes feline sarcoma oncogene (Synonyms: c-fes) | |
Results | Reference |
1 | J:178367 Slamon DJ, Cline MJ, Expression of cellular oncogenes during embryonic and fetal development of the mouse. Proc Natl Acad Sci U S A. 1984 Nov;81(22):7141-5 |
Fev FEV transcription factor, ETS family member (Synonyms: mPet-1, Pet1, Pex1) | |
Results | Reference |
1 | J:237535 Haugas M, Tikker L, Achim K, Salminen M, Partanen J, Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe. Development. 2016 Dec 01;143(23):4495-4508 |
1 | J:152424 Jacob J, Storm R, Castro DS, Milton C, Pla P, Guillemot F, Birchmeier C, Briscoe J, Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain. Development. 2009 Jul;136(14):2477-85 |
1 | J:191410 Ohta Y, Kosaka Y, Kishimoto N, Wang J, Smith SB, Honig G, Kim H, Gasa RM, Neubauer N, Liou A, Tecott LH, Deneris ES, German MS, Convergence of the insulin and serotonin programs in the pancreatic beta-cell. Diabetes. 2011 Dec;60(12):3208-16 |
1 | J:75806 Pfaar H, von Holst A, Vogt Weisenhorn DM, Brodski C, Guimera J, Wurst W, mPet-1, a mouse ETS-domain transcription factor, is expressed in central serotonergic neurons. Dev Genes Evol. 2002 Feb;212(1):43-6 |
1 | J:161774 Wang S, Turner EE, Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity. J Neurosci. 2010 Jul 7;30(27):9224-7 |
1* | J:116706 Zhao ZQ, Scott M, Chiechio S, Wang JS, Renner KJ, Gereau RW 4th, Johnson RL, Deneris ES, Chen ZF, Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity. J Neurosci. 2006 Dec 6;26(49):12781-8 |
Fez1 fasciculation and elongation protein zeta 1 (Synonyms: MGC:19293, UNC-76, UNC76, zygin I) | |
Results | Reference |
1* | J:139974 Sakae N, Yamasaki N, Kitaichi K, Fukuda T, Yamada M, Yoshikawa H, Hiranita T, Tatsumi Y, Kira J, Yamamoto T, Miyakawa T, Nakayama KI, Mice lacking the schizophrenia-associated protein FEZ1 manifest hyperactivity and enhanced responsiveness to psychostimulants. Hum Mol Genet. 2008 Oct 15;17(20):3191-203 |
Fezf1 Fez family zinc finger 1 (Synonyms: 3110069A13Rik, Fez, Zfp312-like) | |
Results | Reference |
1 | J:174726 Eckler MJ, McKenna WL, Taghvaei S, McConnell SK, Chen B, Fezf1 and Fezf2 are required for olfactory development and sensory neuron identity. J Comp Neurol. 2011 Jul 1;519(10):1829-46 |
1 | J:290493 Peng YR, James RE, Yan W, Kay JN, Kolodkin AL, Sanes JR, Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch. Neuron. 2020 Feb 5;105(3):464-474.e6 |
1 | J:311927 Suzuki-Kerr H, Iwagawa T, Sagara H, Mizota A, Suzuki Y, Watanabe S, Pivotal roles of Fezf2 in differentiation of cone OFF bipolar cells and functional maturation of cone ON bipolar cells in retina. Exp Eye Res. 2018 Jun;171:142-154 |
Fezf2 Fez family zinc finger 2 (Synonyms: Fez, Fezl, forebrain embryonic zinc finger, Zfp312) | |
Results | Reference |
1 | J:127387 Armentano M, Chou SJ, Tomassy GS, Leingartner A, O'Leary DD, Studer M, COUP-TFI regulates the balance of cortical patterning between frontal/motor and sensory areas. Nat Neurosci. 2007 Oct;10(10):1277-86 |
1 | J:104387 Chen JG, Rasin MR, Kwan KY, Sestan N, Zfp312 is required for subcortical axonal projections and dendritic morphology of deep-layer pyramidal neurons of the cerebral cortex. Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17792-7 |
1 | J:71409 Hashimoto H, Yabe T, Hirata T, Shimizu T, Bae Y, Yamanaka Y, Hirano T, Hibi M, Expression of the zinc finger gene fez-like in zebrafish forebrain. Mech Dev. 2000 Oct;97(1-2):191-5 |
2 | J:325428 Liu J, Yang M, Su M, Liu B, Zhou K, Sun C, Ba R, Yu B, Zhang B, Zhang Z, Fan W, Wang K, Zhong M, Han J, Zhao C, FOXG1 sequentially orchestrates subtype specification of postmitotic cortical projection neurons. Sci Adv. 2022 May 27;8(21):eabh3568 |
1 | J:192581 Maynard KR, Stein E, DSCAM contributes to dendrite arborization and spine formation in the developing cerebral cortex. J Neurosci. 2012 Nov 21;32(47):16637-50 |
1 | J:226916 McKenna WL, Ortiz-Londono CF, Mathew TK, Hoang K, Katzman S, Chen B, Mutual regulation between Satb2 and Fezf2 promotes subcerebral projection neuron identity in the developing cerebral cortex. Proc Natl Acad Sci U S A. 2015 Sep 15;112(37):11702-7 |
2* | J:232723 Qu C, Bian D, Li X, Xiao J, Wu C, Li Y, Jiang T, Zhou X, Qu J, Chen JG, Transient Expression of Fez Family Zinc Finger 2 Protein Regulates the Brn3b Gene in Developing Retinal Ganglion Cells. J Biol Chem. 2016 Apr 1;291(14):7661-8 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:311927 Suzuki-Kerr H, Iwagawa T, Sagara H, Mizota A, Suzuki Y, Watanabe S, Pivotal roles of Fezf2 in differentiation of cone OFF bipolar cells and functional maturation of cone ON bipolar cells in retina. Exp Eye Res. 2018 Jun;171:142-154 |
1 | J:188109 Tan SL, Nishi M, Ohtsuka T, Matsui T, Takemoto K, Kamio-Miura A, Aburatani H, Shinkai Y, Kageyama R, Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development. Development. 2012 Oct;139(20):3806-16 |
1 | J:306633 Tsyporin J, Tastad D, Ma X, Nehme A, Finn T, Huebner L, Liu G, Gallardo D, Makhamreh A, Roberts JM, Katzman S, Sestan N, McConnell SK, Yang Z, Qiu S, Chen B, Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons. Cell Rep. 2021 Jun;35 |
Fga fibrinogen alpha chain (Synonyms: ENSMUSG00000059807, Fib) | |
Results | Reference |
1* | J:65092 Ishiguro K, Kojima T, Kadomatsu K, Nakayama Y, Takagi A, Suzuki M, Takeda N, Ito M, Yamamoto K, Matsushita T, Kusugami K, Muramatsu T, Saito H, Complete antithrombin deficiency in mice results in embryonic lethality. J Clin Invest. 2000 Oct;106(7):873-8 |
Fgb fibrinogen beta chain (Synonyms: 2510049G14Rik) | |
Results | Reference |
1* | J:65092 Ishiguro K, Kojima T, Kadomatsu K, Nakayama Y, Takagi A, Suzuki M, Takeda N, Ito M, Yamamoto K, Matsushita T, Kusugami K, Muramatsu T, Saito H, Complete antithrombin deficiency in mice results in embryonic lethality. J Clin Invest. 2000 Oct;106(7):873-8 |
Fgd1 FYVE, RhoGEF and PH domain containing 1 (Synonyms: faciogenital dysplasia, ZFYVE3) | |
Results | Reference |
1 | J:63717 Gorski JL, Estrada L, Hu C, Liu Z, Skeletal-specific expression of fgd1 during bone formation and skeletal defects in faciogenital dysplasia (FGDY; aarskog syndrome). Dev Dyn. 2000 Aug;218(4):573-86 |
Fgf1 fibroblast growth factor 1 (Synonyms: Fgf-1, Fgfa, fibroblast growth factor 1 (acidic)) | |
Results | Reference |
1 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1 | J:67299 Arikawa-Hirasawa E, Watanabe H, Takami H, Hassell JR, Yamada Y, Perlecan is essential for cartilage and cephalic development. Nat Genet. 1999 Nov;23(3):354-8 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:117768 Nie X, Developmentally regulated expression of MSX1, MSX2 and Fgfs in the developing mouse cranial base. Angle Orthod. 2006 Nov;76(6):990-5 |
1 | J:167091 Nyeng P, Bjerke MA, Norgaard GA, Qu X, Kobberup S, Jensen J, Fibroblast growth factor 10 represses premature cell differentiation during establishment of the intestinal progenitor niche. Dev Biol. 2011 Jan 1;349(1):20-34 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
Fgf2 fibroblast growth factor 2 (Synonyms: bFGF, Fgf-2, Fgfb) | |
Results | Reference |
1 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1 | J:105236 Cam Y, Neumann MR, Oliver L, Raulais D, Janet T, Ruch JV, Immunolocalization of acidic and basic fibroblast growth factors during mouse odontogenesis. Int J Dev Biol. 1992 Sep;36(3):381-9 |
1 | J:185530 Chan KM, Wong HL, Jin G, Liu B, Cao R, Cao Y, Lehti K, Tryggvason K, Zhou Z, MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis. Dev Cell. 2012 Jun 12;22(6):1176-90 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:43065 Iseki S, Wilkie AO, Heath JK, Ishimaru T, Eto K, Morriss-Kay GM, Fgfr2 and osteopontin domains in the developing skull vault are mutually exclusive and can be altered by locally applied FGF2. Development. 1997 Sep;124(17):3375-84 |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1 | J:233640 Kyrylkova K, Iwaniec UT, Philbrick KA, Leid M, BCL11B regulates sutural patency in the mouse craniofacial skeleton. Dev Biol. 2016 Jul 15;415(2):251-60 |
1 | J:72550 Li C, Guo H, Xu X, Weinberg W, Deng CX, Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning. Dev Dyn. 2001 Nov;222(3):471-83 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:117768 Nie X, Developmentally regulated expression of MSX1, MSX2 and Fgfs in the developing mouse cranial base. Angle Orthod. 2006 Nov;76(6):990-5 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Fgf3 fibroblast growth factor 3 (Synonyms: Fgf-3, Int-2, Int-P) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:8441 Jakobovits A, Shackleford GM, Varmus HE, Martin GR, Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development. Proc Natl Acad Sci U S A. 1986 Oct;83(20):7806-10 |
1 | J:118173 Jarvinen E, Salazar-Ciudad I, Birchmeier W, Taketo MM, Jernvall J, Thesleff I, Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18627-32 |
1 | J:327415 Jing J, Feng J, Yuan Y, Guo T, Lei J, Pei F, Ho TV, Chai Y, Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022 Aug 16;13(1):4803 |
1 | J:65684 Kettunen P, Laurikkala J, Itaranta P, Vainio S, Itoh N, Thesleff I, Associations of FGF-3 and FGF-10 with signaling networks regulating tooth morphogenesis. Dev Dyn. 2000 Nov;219(3):322-32 |
1 | J:130572 Klein OD, Lyons DB, Balooch G, Marshall GW, Basson MA, Peterka M, Boran T, Peterkova R, Martin GR, An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development. 2008 Jan;135(2):377-85 |
1 | J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:167091 Nyeng P, Bjerke MA, Norgaard GA, Qu X, Kobberup S, Jensen J, Fibroblast growth factor 10 represses premature cell differentiation during establishment of the intestinal progenitor niche. Dev Biol. 2011 Jan 1;349(1):20-34 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1 | J:293345 Urness LD, Wang X, Doan H, Shumway N, Noyes CA, Gutierrez-Magana E, Lu R, Mansour SL, Spatial and temporal inhibition of FGFR2b ligands reveals continuous requirements and novel targets in mouse inner ear morphogenesis. Development. 2018 Dec 18;145(24):dev170142 |
1 | J:29475 Wilkinson DG, Bhatt S, McMahon AP, Expression pattern of the FGF-related proto-oncogene int-2 suggests multiple roles in fetal development. Development. 1989 Jan;105(1):131-6 |
2* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
2* | J:173972 Zhao H, Li S, Han D, Kaartinen V, Chai Y, Alk5-mediated transforming growth factor beta signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol. 2011 May;31(10):2079-89 |
Fgf4 fibroblast growth factor 4 (Synonyms: Fgf-4, Fgfk, Hst1, Hstf-1, kFGF) | |
Results | Reference |
2 | J:350005 Adasooriya D, Jeong JK, Kyeong M, Kan S, Kim J, Cho ES, Cho SW, Notum regulates the cusp and root patterns in mouse molar. Sci Rep. 2024 Jun 13;14(1):13633 |
1 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:214032 Ishida K, Yuge Y, Hanaoka M, Yasukawa M, Minami Y, Ogawa M, Masumoto KH, Shigeyoshi Y, Saito M, Tsuji T, Gadd45g regulates dental epithelial cell proliferation through p38 MAPK-mediated p21 expression. Genes Cells. 2013 Aug;18(8):660-71 |
1* | J:21056 Jernvall J, Kettunen P, Karavanova I, Martin LB, Thesleff I, Evidence for the role of the enamel knot as a control center in mammalian tooth cusp formation: non-dividing cells express growth stimulating Fgf-4 gene. Int J Dev Biol. 1994 Sep;38(3):463-9 |
1* | J:101382 Kassai Y, Munne P, Hotta Y, Penttila E, Kavanagh K, Ohbayashi N, Takada S, Thesleff I, Jernvall J, Itoh N, Regulation of mammalian tooth cusp patterning by ectodin. Science. 2005 Sep 23;309(5743):2067-70 |
1 | J:51084 Keranen SV, Aberg T, Kettunen P, Thesleff I, Jernvall J, Association of developmental regulatory genes with the development of different molar tooth shapes in two species of rodents. Dev Genes Evol. 1998 Nov;208(9):477-86 |
1 | J:46744 Kettunen P, Thesleff I, Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis. Dev Dyn. 1998 Mar;211(3):256-68 |
1 | J:233640 Kyrylkova K, Iwaniec UT, Philbrick KA, Leid M, BCL11B regulates sutural patency in the mouse craniofacial skeleton. Dev Biol. 2016 Jul 15;415(2):251-60 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:353047 Nevorankova P, Sulcova M, Kavkova M, Zimcik D, Balkova SM, Peleskova K, Kristekova D, Jakesova V, Zikmund T, Kaiser J, Hola LI, Kolar M, Buchtova M, Region-specific gene expression profiling of early mouse mandible uncovered SATB2 as a key molecule for teeth patterning. Sci Rep. 2024 Aug 6;14(1):18212 |
1 | J:135432 Nightingale SS, Western P, Hutson JM, The migrating gubernaculum grows like a 'limb bud'. J Pediatr Surg. 2008 Feb;43(2):387-90 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1 | J:140401 Xu X, Han J, Ito Y, Bringas P Jr, Deng C, Chai Y, Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-beta/BMP signaling during tooth and palate development. Dev Cell. 2008 Aug;15(2):322-9 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
Fgf5 fibroblast growth factor 5 (Synonyms: Fgf-5) | |
Results | Reference |
1 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
Fgf6 fibroblast growth factor 6 (Synonyms: Fgf-6) | |
Results | Reference |
1 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1* | J:12606 deLapeyriere O, Ollendorff V, Planche J, Ott MO, Pizette S, Coulier F, Birnbaum D, Expression of the Fgf6 gene is restricted to developing skeletal muscle in the mouse embryo. Development. 1993 Jun;118(2):601-11 |
1 | J:184019 Han D, Zhao H, Parada C, Hacia JG, Bringas P Jr, Chai Y, A TGFbeta-Smad4-Fgf6 signaling cascade controls myogenic differentiation and myoblast fusion during tongue development. Development. 2012 May;139(9):1640-50 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:356701 Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD, Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr;91(4):387-93 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
Fgf7 fibroblast growth factor 7 (Synonyms: Keratinocyte growth factor, Kgf) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:72550 Li C, Guo H, Xu X, Weinberg W, Deng CX, Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning. Dev Dyn. 2001 Nov;222(3):471-83 |
1 | J:213341 Li W, Lin CY, Shang C, Han P, Xiong Y, Lin CJ, Yang J, Selleri L, Chang CP, Pbx1 activates Fgf10 in the mesenchyme of developing lungs. Genesis. 2014 May;52(5):399-407 |
1* | J:16888 Mason IJ, Fuller-Pace F, Smith R, Dickson C, FGF-7 (keratinocyte growth factor) expression during mouse development suggests roles in myogenesis, forebrain regionalisation and epithelial-mesenchymal interactions. Mech Dev. 1994 Jan;45(1):15-30 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:167091 Nyeng P, Bjerke MA, Norgaard GA, Qu X, Kobberup S, Jensen J, Fibroblast growth factor 10 represses premature cell differentiation during establishment of the intestinal progenitor niche. Dev Biol. 2011 Jan 1;349(1):20-34 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
1 | J:161760 Provost PR, Simard M, Tremblay Y, A link between lung androgen metabolism and the emergence of mature epithelial type II cells. Am J Respir Crit Care Med. 2004 Aug 1;170(3):296-305 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
Fgf8 fibroblast growth factor 8 (Synonyms: Aigf, Fgf-8) | |
Results | Reference |
1 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1 | J:195145 Amaniti EM, Hasenpusch-Theil K, Li Z, Magnani D, Kessaris N, Mason JO, Theil T, Gli3 is required in Emx1(+) progenitors for the development of the corpus callosum. Dev Biol. 2013 Apr 15;376(2):113-24 |
4 | J:206944 Clegg JM, Conway CD, Howe KM, Price DJ, Mason JO, Turnbull JE, Basson MA, Pratt T, Heparan sulfotransferases Hs6st1 and Hs2st Keep Erk in check for mouse corpus callosum development. J Neurosci. 2014 Feb 5;34(6):2389-401 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1 | J:153202 Gerber SD, Steinberg F, Beyeler M, Villiger PM, Trueb B, The murine Fgfrl1 receptor is essential for the development of the metanephric kidney. Dev Biol. 2009 Nov 1;335(1):106-19 |
1 | J:240770 Gobius I, Morcom L, Suarez R, Bunt J, Bukshpun P, Reardon W, Dobyns WB, Rubenstein JL, Barkovich AJ, Sherr EH, Richards LJ, Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum. Cell Rep. 2016 Oct 11;17(3):735-747 |
1 | J:101176 Grieshammer U, Cebrian C, Ilagan R, Meyers E, Herzlinger D, Martin GR, FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons. Development. 2005 Sep;132(17):3847-57 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:152264 Koo SK, Hill JK, Hwang CH, Lin ZS, Millen KJ, Wu DK, Lmx1a maintains proper neurogenic, sensory, and non-sensory domains in the mammalian inner ear. Dev Biol. 2009 Sep 1;333(1):14-25 |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1 | J:239944 Lorenzen SM, Duggan A, Osipovich AB, Magnuson MA, Garcia-Anoveros J, Insm1 promotes neurogenic proliferation in delaminated otic progenitors. Mech Dev. 2015 Nov;138 Pt 3:233-45 |
1* | J:23751 MacArthur CA, Shankar DB, Shackleford GM, Fgf-8, activated by proviral insertion, cooperates with the Wnt-1 transgene in murine mammary tumorigenesis. J Virol. 1995 Apr;69(4):2501-7 |
1 | J:217046 Magnani D, Hasenpusch-Theil K, Benadiba C, Yu T, Basson MA, Price DJ, Lebrand C, Theil T, Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Cereb Cortex. 2014 Jan;24(1):186-98 |
1* | J:28252 Mahmood R, Bresnick J, Hornbruch A, Mahony C, Morton N, Colquhoun K, Martin P, Lumsden A, Dickson C, Mason I, A role for FGF-8 in the initiation and maintenance of vertebrate limb bud outgrowth. Curr Biol. 1995 Jul 1;5(7):797-806 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:120229 Narlis M, Grote D, Gaitan Y, Boualia SK, Bouchard M, Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney. J Am Soc Nephrol. 2007 Apr;18(4):1121-9 |
1 | J:135432 Nightingale SS, Western P, Hutson JM, The migrating gubernaculum grows like a 'limb bud'. J Pediatr Surg. 2008 Feb;43(2):387-90 |
1 | J:78879 Pirvola U, Ylikoski J, Trokovic R, Hebert JM, McConnell SK, Partanen J, FGFR1 is required for the development of the auditory sensory epithelium. Neuron. 2002 Aug 15;35(4):671-80 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1 | J:267715 Wiwatpanit T, Lorenzen SM, Cantu JA, Foo CZ, Hogan AK, Marquez F, Clancy JC, Schipma MJ, Cheatham MA, Duggan A, Garcia-Anoveros J, Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1. Nature. 2018 Nov;563(7733):691-695 |
1 | J:281388 Xu J, Huang Z, Wang W, Tan X, Li H, Zhang Y, Tian W, Hu T, Chen YP, FGF8 Signaling Alters the Osteogenic Cell Fate in the Hard Palate. J Dent Res. 2018 May;97(5):589-596 |
1* | J:56088 Xu J, Lawshe A, MacArthur CA, Ornitz DM, Genomic structure, mapping, activity and expression of fibroblast growth factor 17. Mech Dev. 1999 May;83(1-2):165-78 |
2* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
3 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
1* | J:165724 Yu S, Poe B, Schwarz M, Elliot SA, Albertine KH, Fenton S, Garg V, Moon AM, Fetal and postnatal lung defects reveal a novel and required role for Fgf8 in lung development. Dev Biol. 2010 Nov 1;347(1):92-108 |
1 | J:315014 Zhou C, Chen D, Ren J, Huang D, Li R, Luo H, Guan C, Cao Y, Wang W, FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex. J Cell Mol Med. 2021 Mar;25(6):3051-3062 |
Fgf9 fibroblast growth factor 9 (Synonyms: Eks, glia activating factor) | |
Results | Reference |
1* | J:57294 Colvin JS, Feldman B, Nadeau JH, Goldfarb M, Ornitz DM, Genomic organization and embryonic expression of the mouse fibroblast growth factor 9 gene. Dev Dyn. 1999 Sep;216(1):72-88 |
1 | J:216295 Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC, FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. 2014 Nov 1;395(1):50-61 |
1* | J:139637 Hotta Y, Sasaki S, Konishi M, Kinoshita H, Kuwahara K, Nakao K, Itoh N, Fgf16 is required for cardiomyocyte proliferation in the mouse embryonic heart. Dev Dyn. 2008 Sep 24;237(10):2947-2954 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:46744 Kettunen P, Thesleff I, Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis. Dev Dyn. 1998 Mar;211(3):256-68 |
1 | J:130572 Klein OD, Lyons DB, Balooch G, Marshall GW, Basson MA, Peterka M, Boran T, Peterkova R, Martin GR, An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development. 2008 Jan;135(2):377-85 |
1 | J:233640 Kyrylkova K, Iwaniec UT, Philbrick KA, Leid M, BCL11B regulates sutural patency in the mouse craniofacial skeleton. Dev Biol. 2016 Jul 15;415(2):251-60 |
1 | J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:117768 Nie X, Developmentally regulated expression of MSX1, MSX2 and Fgfs in the developing mouse cranial base. Angle Orthod. 2006 Nov;76(6):990-5 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
1 | J:93155 Pirvola U, Zhang X, Mantela J, Ornitz DM, Ylikoski J, Fgf9 signaling regulates inner ear morphogenesis through epithelial-mesenchymal interactions. Dev Biol. 2004 Sep 15;273(2):350-60 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1 | J:154601 Seuntjens E, Nityanandam A, Miquelajauregui A, Debruyn J, Stryjewska A, Goebbels S, Nave KA, Huylebroeck D, Tarabykin V, Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors. Nat Neurosci. 2009 Nov;12(11):1373-80 |
1* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
2* | J:173972 Zhao H, Li S, Han D, Kaartinen V, Chai Y, Alk5-mediated transforming growth factor beta signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol. 2011 May;31(10):2079-89 |
Fgf10 fibroblast growth factor 10 (Synonyms: AEY17, FGF-10, Gsfaey17) | |
Results | Reference |
1 | J:239948 Al Alam D, El Agha E, Sakurai R, Kheirollahi V, Moiseenko A, Danopoulos S, Shrestha A, Schmoldt C, Quantius J, Herold S, Chao CM, Tiozzo C, De Langhe S, Plikus MV, Thornton M, Grubbs B, Minoo P, Rehan VK, Bellusci S, Evidence for the involvement of fibroblast growth factor 10 in lipofibroblast formation during embryonic lung development. Development. 2015 Dec 01;142(23):4139-50 |
1 | J:89611 Asaki T, Konishi M, Miyake A, Kato S, Tomizawa M, Itoh N, Roles of fibroblast growth factor 10 (Fgf10) in adipogenesis in vivo. Mol Cell Endocrinol. 2004 Apr 15;218(1-2):119-28 |
1 | J:111051 Cui CY, Hashimoto T, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9142-7 |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
1 | J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:233686 Jia WJ, Jiang S, Tang QL, Shen D, Xue B, Ning W, Li CJ, Geranylgeranyl Diphosphate Synthase Modulates Fetal Lung Branching Morphogenesis Possibly through Controlling K-Ras Prenylation. Am J Pathol. 2016 Jun;186(6):1454-65 |
1 | J:65684 Kettunen P, Laurikkala J, Itaranta P, Vainio S, Itoh N, Thesleff I, Associations of FGF-3 and FGF-10 with signaling networks regulating tooth morphogenesis. Dev Dyn. 2000 Nov;219(3):322-32 |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1 | J:130572 Klein OD, Lyons DB, Balooch G, Marshall GW, Basson MA, Peterka M, Boran T, Peterkova R, Martin GR, An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development. 2008 Jan;135(2):377-85 |
1 | J:233640 Kyrylkova K, Iwaniec UT, Philbrick KA, Leid M, BCL11B regulates sutural patency in the mouse craniofacial skeleton. Dev Biol. 2016 Jul 15;415(2):251-60 |
1 | J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670 |
1 | J:72550 Li C, Guo H, Xu X, Weinberg W, Deng CX, Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning. Dev Dyn. 2001 Nov;222(3):471-83 |
3 | J:213341 Li W, Lin CY, Shang C, Han P, Xiong Y, Lin CJ, Yang J, Selleri L, Chang CP, Pbx1 activates Fgf10 in the mesenchyme of developing lungs. Genesis. 2014 May;52(5):399-407 |
1 | J:214993 Lin C, Chen MH, Yao E, Song H, Gacayan R, Hui CC, Chuang PT, Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development. Dev Biol. 2014 Aug 15;392(2):324-33 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1* | J:237227 May AJ, Headon D, Rice DP, Noble A, Tucker AS, FGF and EDA pathways control initiation and branching of distinct subsets of developing nasal glands. Dev Biol. 2016 Nov 15;419(2):348-356 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:266862 Morosan-Puopolo G, Balakrishnan-Renuka A, Yusuf F, Chen J, Dai F, Zoidl G, Ludtke TH, Kispert A, Theiss C, Abdelsabour-Khalaf M, Brand-Saberi B, Wnt11 is required for oriented migration of dermogenic progenitor cells from the dorsomedial lip of the avian dermomyotome. PLoS One. 2014;9(3):e92679 |
1 | J:218295 Mortensen AH, Schade V, Lamonerie T, Camper SA, Deletion of OTX2 in neural ectoderm delays anterior pituitary development. Hum Mol Genet. 2015 Feb 15;24(4):939-53 |
1 | J:167091 Nyeng P, Bjerke MA, Norgaard GA, Qu X, Kobberup S, Jensen J, Fibroblast growth factor 10 represses premature cell differentiation during establishment of the intestinal progenitor niche. Dev Biol. 2011 Jan 1;349(1):20-34 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
1 | J:72516 Pirvola U, Spencer-Dene B, Xing-Qun L, Kettunen P, Thesleff I, Fritzsch B, Dickson C, Ylikoski J, FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis. J Neurosci. 2000 Aug 15;20(16):6125-34 |
1 | J:78879 Pirvola U, Ylikoski J, Trokovic R, Hebert JM, McConnell SK, Partanen J, FGFR1 is required for the development of the auditory sensory epithelium. Neuron. 2002 Aug 15;35(4):671-80 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1 | J:154951 Sahara S, O'Leary DD, Fgf10 regulates transition period of cortical stem cell differentiation to radial glia controlling generation of neurons and basal progenitors. Neuron. 2009 Jul 16;63(1):48-62 |
1 | J:286655 Sakamoto S, Tateya T, Omori K, Kageyama R, Id genes are required for morphogenesis and cellular patterning in the developing mammalian cochlea. Dev Biol. 2020 Apr 15;460(2):164-175 |
2 | J:167739 Sala FG, Del Moral PM, Tiozzo C, Alam DA, Warburton D, Grikscheit T, Veltmaat JM, Bellusci S, FGF10 controls the patterning of the tracheal cartilage rings via Shh. Development. 2011 Jan;138(2):273-82 |
1 | J:236733 Shibuya M, Ikari T, Sugiyama G, Ohyama Y, Kumamaru W, Nagano K, Sugiura T, Shirasuna K, Mori Y, Efficient regulation of branching morphogenesis via fibroblast growth factor receptor 2c in early-stage embryonic mouse salivary glands. Differentiation. 2016 Oct - Nov;92(4):216-224 |
1* | J:64492 Suzuki K, Yamanishi K, Mori O, Kamikawa M, Andersen B, Kato S, Toyoda T, Yamada G, Defective terminal differentiation and hypoplasia of the epidermis in mice lacking the Fgf10 gene. FEBS Lett. 2000 Sep 8;481(1):53-6 |
1 | J:293345 Urness LD, Wang X, Doan H, Shumway N, Noyes CA, Gutierrez-Magana E, Lu R, Mansour SL, Spatial and temporal inhibition of FGFR2b ligands reveals continuous requirements and novel targets in mouse inner ear morphogenesis. Development. 2018 Dec 18;145(24):dev170142 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
1* | J:165724 Yu S, Poe B, Schwarz M, Elliot SA, Albertine KH, Fenton S, Garg V, Moon AM, Fetal and postnatal lung defects reveal a novel and required role for Fgf8 in lung development. Dev Biol. 2010 Nov 1;347(1):92-108 |
2* | J:173972 Zhao H, Li S, Han D, Kaartinen V, Chai Y, Alk5-mediated transforming growth factor beta signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol. 2011 May;31(10):2079-89 |
Fgf11 fibroblast growth factor 11 (Synonyms: Fhf3) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
Fgf12 fibroblast growth factor 12 (Synonyms: Fhf1) | |
Results | Reference |
1* | J:41392 Hartung H, Feldman B, Lovec H, Coulier F, Birnbaum D, Goldfarb M, Murine FGF-12 and FGF-13: expression in embryonic nervous system, connective tissue and heart. Mech Dev. 1997 Jun;64(1-2):31-9 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
Fgf13 fibroblast growth factor 13 (Synonyms: Fhf2) | |
Results | Reference |
1* | J:318018 DeStefano GM, Fantauzzo KA, Petukhova L, Kurban M, Tadin-Strapps M, Levy B, Warburton D, Cirulli ET, Han Y, Sun X, Shen Y, Shirazi M, Jobanputra V, Cepeda-Valdes R, Cesar Salas-Alanis J, Christiano AM, Position effect on FGF13 associated with X-linked congenital generalized hypertrichosis. Proc Natl Acad Sci U S A. 2013 May 7;110(19):7790-5 |
1* | J:41392 Hartung H, Feldman B, Lovec H, Coulier F, Birnbaum D, Goldfarb M, Murine FGF-12 and FGF-13: expression in embryonic nervous system, connective tissue and heart. Mech Dev. 1997 Jun;64(1-2):31-9 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
Fgf14 fibroblast growth factor 14 (Synonyms: Fhf4) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1* | J:60428 Wang Q, McEwen DG, Ornitz DM, Subcellular and developmental expression of alternatively spliced forms of fibroblast growth factor 14. Mech Dev. 2000 Feb;90(2):283-7 |
Fgf15 fibroblast growth factor 15 (Synonyms: FGF19) | |
Results | Reference |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1* | J:85711 Gimeno L, Brulet P, Martinez S, Study of Fgf15 gene expression in developing mouse brain. Gene Expr Patterns. 2003 Aug;3(4):473-81 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
Fgf16 fibroblast growth factor 16 | |
Results | Reference |
1* | J:139718 Hatch EP, Urness LD, Mansour SL, Fgf16(IRESCre) mice: a tool to inactivate genes expressed in inner ear cristae and spiral prominence epithelium. Dev Dyn. 2009 Feb;238(2):358-66 |
1* | J:139637 Hotta Y, Sasaki S, Konishi M, Kinoshita H, Kuwahara K, Nakao K, Itoh N, Fgf16 is required for cardiomyocyte proliferation in the mouse embryonic heart. Dev Dyn. 2008 Sep 24;237(10):2947-2954 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
Fgf17 fibroblast growth factor 17 | |
Results | Reference |
1 | J:121300 Cholfin JA, Rubenstein JL, Patterning of frontal cortex subdivisions by Fgf17. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7652-7 |
2 | J:272376 Clegg JM, Parkin HM, Mason JO, Pratt T, Heparan Sulfate Sulfation by Hs2st Restricts Astroglial Precursor Somal Translocation in Developing Mouse Forebrain by a Non-Cell-Autonomous Mechanism. J Neurosci. 2019 Feb 20;39(8):1386-1404 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:56088 Xu J, Lawshe A, MacArthur CA, Ornitz DM, Genomic structure, mapping, activity and expression of fibroblast growth factor 17. Mech Dev. 1999 May;83(1-2):165-78 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
3 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
Fgf18 fibroblast growth factor 18 (Synonyms: D130055P09Rik, FGF-18) | |
Results | Reference |
1 | J:185530 Chan KM, Wong HL, Jin G, Liu B, Cao R, Cao Y, Lehti K, Tryggvason K, Zhou Z, MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis. Dev Cell. 2012 Jun 12;22(6):1176-90 |
1 | J:332217 Feng J, Han X, Yuan Y, Cho CK, Janeckova E, Guo T, Pareek S, Rahman MS, Zheng B, Bi J, Jing J, Zhang M, Xu J, Ho TV, Chai Y, TGF-beta signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development. Elife. 2022 Dec 21;11 |
2* | J:76230 Hajihosseini MK, Heath JK, Expression patterns of fibroblast growth factors-18 and -20 in mouse embryos is suggestive of novel roles in calvarial and limb development. Mech Dev. 2002 Apr;113(1):79-83 |
1 | J:93900 Hasegawa H, Ashigaki S, Takamatsu M, Suzuki-Migishima R, Ohbayashi N, Itoh N, Takada S, Tanabe Y, Laminar patterning in the developing neocortex by temporally coordinated fibroblast growth factor signaling. J Neurosci. 2004 Oct 6;24(40):8711-9 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:233640 Kyrylkova K, Iwaniec UT, Philbrick KA, Leid M, BCL11B regulates sutural patency in the mouse craniofacial skeleton. Dev Biol. 2016 Jul 15;415(2):251-60 |
1 | J:316483 Leek CC, Soulas JM, Bhattacharya I, Ganji E, Locke RC, Smith MC, Bhavsar JD, Polson SW, Ornitz DM, Killian ML, Deletion of Fibroblast growth factor 9 globally and in skeletal muscle results in enlarged tuberosities at sites of deltoid tendon attachments. Dev Dyn. 2021 Dec;250(12):1778-1795 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:117768 Nie X, Developmentally regulated expression of MSX1, MSX2 and Fgfs in the developing mouse cranial base. Angle Orthod. 2006 Nov;76(6):990-5 |
1 | J:75880 Ohbayashi N, Shibayama M, Kurotaki Y, Imanishi M, Fujimori T, Itoh N, Takada S, FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev. 2002 Apr 1;16(7):870-9 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:143455 Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Al Awqati Q, Ballabio A, Karsenty G, Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification. Genes Dev. 2008 Oct 1;22(19):2645-50 |
1 | J:91986 Usui H, Shibayama M, Ohbayashi N, Konishi M, Takada S, Itoh N, Fgf18 is required for embryonic lung alveolar development. Biochem Biophys Res Commun. 2004 Sep 24;322(3):887-92 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
Fgf20 fibroblast growth factor 20 | |
Results | Reference |
1 | J:185582 Barak H, Huh SH, Chen S, Jeanpierre C, Martinovic J, Parisot M, Bole-Feysot C, Nitschke P, Salomon R, Antignac C, Ornitz DM, Kopan R, FGF9 and FGF20 Maintain the Stemness of Nephron Progenitors in Mice and Man. Dev Cell. 2012 Jun 12;22(6):1191-207 |
1 | J:252728 Elo T, Lindfors PH, Lan Q, Voutilainen M, Trela E, Ohlsson C, Huh SH, Ornitz DM, Poutanen M, Howard BA, Mikkola ML, Ectodysplasin target gene Fgf20 regulates mammary bud growth and ductal invasion and branching during puberty. Sci Rep. 2017 Jul 11;7(1):5049 |
1 | J:334122 Glover JD, Sudderick ZR, Shih BB, Batho-Samblas C, Charlton L, Krause AL, Anderson C, Riddell J, Balic A, Li J, Klika V, Woolley TE, Gaffney EA, Corsinotti A, Anderson RA, Johnston LJ, Brown SJ, Wang S, Chen Y, Crichton ML, Headon DJ, The developmental basis of fingerprint pattern formation and variation. Cell. 2023 Mar 2;186(5):940-956.e20 |
2* | J:314568 Haara O, Harjunmaa E, Lindfors PH, Huh SH, Fliniaux I, Aberg T, Jernvall J, Ornitz DM, Mikkola ML, Thesleff I, Ectodysplasin regulates activator-inhibitor balance in murine tooth development through Fgf20 signaling. Development. 2012 Sep;139(17):3189-99 |
1 | J:137155 Hayashi T, Ray CA, Bermingham-McDonogh O, Fgf20 is required for sensory epithelial specification in the developing cochlea. J Neurosci. 2008 Jun 4;28(23):5991-9 |
1* | J:139637 Hotta Y, Sasaki S, Konishi M, Kinoshita H, Kuwahara K, Nakao K, Itoh N, Fgf16 is required for cardiomyocyte proliferation in the mouse embryonic heart. Dev Dyn. 2008 Sep 24;237(10):2947-2954 |
1 | J:193958 Huh SH, Narhi K, Lindfors PH, Haara O, Yang L, Ornitz DM, Mikkola ML, Fgf20 governs formation of primary and secondary dermal condensations in developing hair follicles. Genes Dev. 2013 Feb 15;27(4):450-8 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1 | J:188114 Munnamalai V, Hayashi T, Bermingham-McDonogh O, Notch prosensory effects in the Mammalian cochlea are partially mediated by fgf20. J Neurosci. 2012 Sep 12;32(37):12876-84 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
Fgf21 fibroblast growth factor 21 | |
Results | Reference |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
Fgf22 fibroblast growth factor 22 (Synonyms: 2210414E06Rik) | |
Results | Reference |
2 | J:84622 Beyer TA, Werner S, Dickson C, Grose R, Fibroblast growth factor 22 and its potential role during skin development and repair. Exp Cell Res. 2003 Jul 15;287(2):228-36 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
Fgf23 fibroblast growth factor 23 | |
Results | Reference |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
Fgfbp1 fibroblast growth factor binding protein 1 (Synonyms: FGF-BP) | |
Results | Reference |
1* | J:40964 Kurtz A, Wang HL, Darwiche N, Harris V, Wellstein A, Expression of a binding protein for FGF is associated with epithelial development and skin carcinogenesis. Oncogene. 1997 Jun 5;14(22):2671-81 |
Fgfr1 fibroblast growth factor receptor 1 (Synonyms: Eask, Fgfr-1, FGFR-I, Flt-2, Fr1, Hspy) | |
Results | Reference |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
1* | J:203801 Amann R, Trueb B, Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1. Int J Mol Med. 2013 Nov;32(5):983-8 |
1 | J:91667 Antonopoulou I, Mavrogiannis LA, Wilkie AO, Morriss-Kay GM, Alx4 and Msx2 play phenotypically similar and additive roles in skull vault differentiation. J Anat. 2004 Jun;204(6):487-99 |
1* | J:168038 Bimonte S, De Angelis A, Quagliata L, Giusti F, Tammaro R, Dallai R, Ascenzi MG, Diez-Roux G, Franco B, Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol. 2011 Jan 15;349(2):179-91 |
1 | J:353439 de Jaime-Soguero A, Hattemer J, Bufe A, Haas A, van den Berg J, van Batenburg V, Das B, di Marco B, Androulaki S, Bohly N, Landry JJM, Schoell B, Rosa VS, Villacorta L, Baskan Y, Trapp M, Benes V, Chabes A, Shahbazi M, Jauch A, Engel U, Patrizi A, Sotillo R, van Oudenaarden A, Bageritz J, Alfonso J, Bastians H, Acebron SP, Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress. Nat Commun. 2024 Aug 28;15(1):7404 |
1 | J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767 |
1 | J:240770 Gobius I, Morcom L, Suarez R, Bunt J, Bukshpun P, Reardon W, Dobyns WB, Rubenstein JL, Barkovich AJ, Sherr EH, Richards LJ, Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum. Cell Rep. 2016 Oct 11;17(3):735-747 |
2* | J:236374 Goldie SJ, Arhatari BD, Anderson P, Auden A, Partridge DD, Jane SM, Dworkin S, Mice lacking the conserved transcription factor Grainyhead-like 3 (Grhl3) display increased apposition of the frontal and parietal bones during embryonic development. BMC Dev Biol. 2016 Oct 18;16(1):37 |
1 | J:101176 Grieshammer U, Cebrian C, Ilagan R, Meyers E, Herzlinger D, Martin GR, FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons. Development. 2005 Sep;132(17):3847-57 |
1 | J:315113 Hafner R, Bohnenpoll T, Rudat C, Schultheiss TM, Kispert A, Fgfr2 is required for the expansion of the early adrenocortical primordium. Mol Cell Endocrinol. 2015 Sep 15;413:168-77 |
1 | J:93900 Hasegawa H, Ashigaki S, Takamatsu M, Suzuki-Migishima R, Ohbayashi N, Itoh N, Takada S, Tanabe Y, Laminar patterning in the developing neocortex by temporally coordinated fibroblast growth factor signaling. J Neurosci. 2004 Oct 6;24(40):8711-9 |
1 | J:117235 Hayashi T, Cunningham D, Bermingham-McDonogh O, Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti. Dev Dyn. 2007 Feb;236(2):525-33 |
1* | J:156926 Hayashi T, Ray CA, Younkins C, Bermingham-McDonogh O, Expression patterns of FGF receptors in the developing mammalian cochlea. Dev Dyn. 2010 Feb 3;239(3):1019-1026 |
1 | J:160258 Holley M, Rhodes C, Kneebone A, Herde MK, Fleming M, Steel KP, Emx2 and early hair cell development in the mouse inner ear. Dev Biol. 2010 Apr 15;340(2):547-56 |
1 | J:119288 Jacob AL, Smith C, Partanen J, Ornitz DM, Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation. Dev Biol. 2006 Aug 15;296(2):315-28 |
1* | J:280430 Janeckova E, Feng J, Li J, Rodriguez G, Chai Y, Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development. PLoS One. 2019;14(10):e0223879 |
1* | J:61352 Johnson D, Iseki S, Wilkie AO, Morriss-Kay GM, Expression patterns of Twist and Fgfr1, -2 and -3 in the developing mouse coronal suture suggest a key role for twist in suture initiation and biogenesis. Mech Dev. 2000 Mar 1;91(1-2):341-5 |
1 | J:48564 Kettunen P, Karavanova I, Thesleff I, Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9. Dev Genet. 1998;22(4):374-85 |
1 | J:102948 Koziel L, Wuelling M, Schneider S, Vortkamp A, Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation. Development. 2005 Dec;132(23):5249-60 |
1 | J:233640 Kyrylkova K, Iwaniec UT, Philbrick KA, Leid M, BCL11B regulates sutural patency in the mouse craniofacial skeleton. Dev Biol. 2016 Jul 15;415(2):251-60 |
1 | J:74147 Lee S, Crisera CA, Erfani S, Maldonado TS, Lee JJ, Alkasab SL, Longaker MT, Immunolocalization of fibroblast growth factor receptors 1 and 2 in mouse palate development. Plast Reconstr Surg. 2001 Jun;107(7):1776-84; discussion 1785-6 |
1* | J:78262 Lin L, Taylor JS, Chan SO, Changes in expression of fibroblast growth factor receptors during development of the mouse retinofugal pathway. J Comp Neurol. 2002 Sep 9;451(1):22-32 |
1 | J:218941 Meier F, Giesert F, Delic S, Faus-Kessler T, Matheus F, Simeone A, Holter SM, Kuhn R, Weisenhorn DM, Wurst W, Prakash N, FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS One. 2014;9(7):e101124 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:75880 Ohbayashi N, Shibayama M, Kurotaki Y, Imanishi M, Fujimori T, Itoh N, Takada S, FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev. 2002 Apr 1;16(7):870-9 |
2 | J:131109 Ohkubo Y, Uchida AO, Shin D, Partanen J, Vaccarino FM, Fibroblast growth factor receptor 1 is required for the proliferation of hippocampal progenitor cells and for hippocampal growth in mouse. J Neurosci. 2004 Jul 7;24(27):6057-69 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
2* | J:1619 Peters KG, Werner S, Chen G, Williams LT, Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse. Development. 1992 Jan;114(1):233-43 |
1 | J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005 |
1 | J:78879 Pirvola U, Ylikoski J, Trokovic R, Hebert JM, McConnell SK, Partanen J, FGFR1 is required for the development of the auditory sensory epithelium. Neuron. 2002 Aug 15;35(4):671-80 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:356701 Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD, Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr;91(4):387-93 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1 | J:124105 Ruiz-Perez VL, Blair HJ, Rodriguez-Andres ME, Blanco MJ, Wilson A, Liu YN, Miles C, Peters H, Goodship JA, Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. Development. 2007 Aug;134(16):2903-12 |
1 | J:236733 Shibuya M, Ikari T, Sugiyama G, Ohyama Y, Kumamaru W, Nagano K, Sugiura T, Shirasuna K, Mori Y, Efficient regulation of branching morphogenesis via fibroblast growth factor receptor 2c in early-stage embryonic mouse salivary glands. Differentiation. 2016 Oct - Nov;92(4):216-224 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:110263 Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM, Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat Neurosci. 2006 Jun;9(6):787-97 |
1* | J:130737 Tagariello A, Luther J, Streiter M, Didt-Koziel L, Wuelling M, Surmann-Schmitt C, Stock M, Adam N, Vortkamp A, Winterpacht A, Ucma - A novel secreted factor represents a highly specific marker for distal chondrocytes. Matrix Biol. 2008 Jan;27(1):3-11 |
1 | J:149459 Wuelling M, Kaiser FJ, Buelens LA, Braunholz D, Shivdasani RA, Depping R, Vortkamp A, Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. Dev Biol. 2009 Apr 1;328(1):40-53 |
1 | J:281388 Xu J, Huang Z, Wang W, Tan X, Li H, Zhang Y, Tian W, Hu T, Chen YP, FGF8 Signaling Alters the Osteogenic Cell Fate in the Hard Palate. J Dent Res. 2018 May;97(5):589-596 |
2* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
Fgfr1op2 FGFR1 oncogene partner 2 (Synonyms: 1500031J01Rik) | |
Results | Reference |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
Fgfr2 fibroblast growth factor receptor 2 (Synonyms: Bek, Fgfr-2, Fgfr2b, Fgfr-7, Fgfr7, KGFRTr, svs) | |
Results | Reference |
1* | J:203801 Amann R, Trueb B, Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1. Int J Mol Med. 2013 Nov;32(5):983-8 |
1 | J:91667 Antonopoulou I, Mavrogiannis LA, Wilkie AO, Morriss-Kay GM, Alx4 and Msx2 play phenotypically similar and additive roles in skull vault differentiation. J Anat. 2004 Jun;204(6):487-99 |
1* | J:166178 Chen H, Yong W, Hinds TD Jr, Yang Z, Zhou Y, Sanchez ER, Shou W, Fkbp52 regulates androgen receptor transactivation activity and male urethra morphogenesis. J Biol Chem. 2010 Sep 3;285(36):27776-84 |
1 | J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767 |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:216295 Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC, FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. 2014 Nov 1;395(1):50-61 |
1 | J:240770 Gobius I, Morcom L, Suarez R, Bunt J, Bukshpun P, Reardon W, Dobyns WB, Rubenstein JL, Barkovich AJ, Sherr EH, Richards LJ, Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum. Cell Rep. 2016 Oct 11;17(3):735-747 |
1* | J:236374 Goldie SJ, Arhatari BD, Anderson P, Auden A, Partridge DD, Jane SM, Dworkin S, Mice lacking the conserved transcription factor Grainyhead-like 3 (Grhl3) display increased apposition of the frontal and parietal bones during embryonic development. BMC Dev Biol. 2016 Oct 18;16(1):37 |
1 | J:101176 Grieshammer U, Cebrian C, Ilagan R, Meyers E, Herzlinger D, Martin GR, FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons. Development. 2005 Sep;132(17):3847-57 |
1 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
1 | J:315113 Hafner R, Bohnenpoll T, Rudat C, Schultheiss TM, Kispert A, Fgfr2 is required for the expansion of the early adrenocortical primordium. Mol Cell Endocrinol. 2015 Sep 15;413:168-77 |
1 | J:93900 Hasegawa H, Ashigaki S, Takamatsu M, Suzuki-Migishima R, Ohbayashi N, Itoh N, Takada S, Tanabe Y, Laminar patterning in the developing neocortex by temporally coordinated fibroblast growth factor signaling. J Neurosci. 2004 Oct 6;24(40):8711-9 |
1* | J:156926 Hayashi T, Ray CA, Younkins C, Bermingham-McDonogh O, Expression patterns of FGF receptors in the developing mammalian cochlea. Dev Dyn. 2010 Feb 3;239(3):1019-1026 |
2* | J:43065 Iseki S, Wilkie AO, Heath JK, Ishimaru T, Eto K, Morriss-Kay GM, Fgfr2 and osteopontin domains in the developing skull vault are mutually exclusive and can be altered by locally applied FGF2. Development. 1997 Sep;124(17):3375-84 |
1* | J:280430 Janeckova E, Feng J, Li J, Rodriguez G, Chai Y, Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development. PLoS One. 2019;14(10):e0223879 |
1* | J:61352 Johnson D, Iseki S, Wilkie AO, Morriss-Kay GM, Expression patterns of Twist and Fgfr1, -2 and -3 in the developing mouse coronal suture suggest a key role for twist in suture initiation and biogenesis. Mech Dev. 2000 Mar 1;91(1-2):341-5 |
1 | J:48564 Kettunen P, Karavanova I, Thesleff I, Responsiveness of developing dental tissues to fibroblast growth factors: expression of splicing alternatives of FGFR1, -2, -3, and of FGFR4; and stimulation of cell proliferation by FGF-2, -4, -8, and -9. Dev Genet. 1998;22(4):374-85 |
1 | J:233640 Kyrylkova K, Iwaniec UT, Philbrick KA, Leid M, BCL11B regulates sutural patency in the mouse craniofacial skeleton. Dev Biol. 2016 Jul 15;415(2):251-60 |
1 | J:74147 Lee S, Crisera CA, Erfani S, Maldonado TS, Lee JJ, Alkasab SL, Longaker MT, Immunolocalization of fibroblast growth factor receptors 1 and 2 in mouse palate development. Plast Reconstr Surg. 2001 Jun;107(7):1776-84; discussion 1785-6 |
1 | J:72550 Li C, Guo H, Xu X, Weinberg W, Deng CX, Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning. Dev Dyn. 2001 Nov;222(3):471-83 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
2* | J:160674 Mai S, Wei K, Flenniken A, Adamson SL, Rossant J, Aubin JE, Gong SG, The missense mutation W290R in Fgfr2 causes developmental defects from aberrant IIIb and IIIc signaling. Dev Dyn. 2010 Jun;239(6):1888-900 |
1* | J:237227 May AJ, Headon D, Rice DP, Noble A, Tucker AS, FGF and EDA pathways control initiation and branching of distinct subsets of developing nasal glands. Dev Biol. 2016 Nov 15;419(2):348-356 |
1 | J:218941 Meier F, Giesert F, Delic S, Faus-Kessler T, Matheus F, Simeone A, Holter SM, Kuhn R, Weisenhorn DM, Wurst W, Prakash N, FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS One. 2014;9(7):e101124 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:167091 Nyeng P, Bjerke MA, Norgaard GA, Qu X, Kobberup S, Jensen J, Fibroblast growth factor 10 represses premature cell differentiation during establishment of the intestinal progenitor niche. Dev Biol. 2011 Jan 1;349(1):20-34 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
1 | J:75880 Ohbayashi N, Shibayama M, Kurotaki Y, Imanishi M, Fujimori T, Itoh N, Takada S, FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev. 2002 Apr 1;16(7):870-9 |
1 | J:131109 Ohkubo Y, Uchida AO, Shin D, Partanen J, Vaccarino FM, Fibroblast growth factor receptor 1 is required for the proliferation of hippocampal progenitor cells and for hippocampal growth in mouse. J Neurosci. 2004 Jul 7;24(27):6057-69 |
2* | J:1619 Peters KG, Werner S, Chen G, Williams LT, Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse. Development. 1992 Jan;114(1):233-43 |
1* | J:98380 Petiot A, Perriton CL, Dickson C, Cohn MJ, Development of the mammalian urethra is controlled by Fgfr2-IIIb. Development. 2005 May;132(10):2441-50 |
1 | J:72516 Pirvola U, Spencer-Dene B, Xing-Qun L, Kettunen P, Thesleff I, Fritzsch B, Dickson C, Ylikoski J, FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis. J Neurosci. 2000 Aug 15;20(16):6125-34 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:356701 Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD, Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr;91(4):387-93 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1 | J:284150 Roberts RR, Bobzin L, Teng CS, Pal D, Tuzon CT, Schweitzer R, Merrill AE, FGF signaling patterns cell fate at the interface between tendon and bone. Development. 2019 Aug 2;146(15):dev170241 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1* | J:83132 Settle SH Jr, Rountree RB, Sinha A, Thacker A, Higgins K, Kingsley DM, Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes. Dev Biol. 2003 Feb 1;254(1):116-30 |
1 | J:154601 Seuntjens E, Nityanandam A, Miquelajauregui A, Debruyn J, Stryjewska A, Goebbels S, Nave KA, Huylebroeck D, Tarabykin V, Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors. Nat Neurosci. 2009 Nov;12(11):1373-80 |
1 | J:236733 Shibuya M, Ikari T, Sugiyama G, Ohyama Y, Kumamaru W, Nagano K, Sugiura T, Shirasuna K, Mori Y, Efficient regulation of branching morphogenesis via fibroblast growth factor receptor 2c in early-stage embryonic mouse salivary glands. Differentiation. 2016 Oct - Nov;92(4):216-224 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1 | J:91986 Usui H, Shibayama M, Ohbayashi N, Konishi M, Takada S, Itoh N, Fgf18 is required for embryonic lung alveolar development. Biochem Biophys Res Commun. 2004 Sep 24;322(3):887-92 |
1 | J:281388 Xu J, Huang Z, Wang W, Tan X, Li H, Zhang Y, Tian W, Hu T, Chen YP, FGF8 Signaling Alters the Osteogenic Cell Fate in the Hard Palate. J Dent Res. 2018 May;97(5):589-596 |
2* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
2* | J:90391 Yu K, Xu J, Liu Z, Sosic D, Shao J, Olson EN, Towler DA, Ornitz DM, Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development. 2003 Jul;130(13):3063-74 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
Fgfr3 fibroblast growth factor receptor 3 (Synonyms: Fgfr-3, HBGFR, sam3) | |
Results | Reference |
1 | J:90567 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 2004 May 1;18(9):1072-87 |
2 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
1* | J:203801 Amann R, Trueb B, Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1. Int J Mol Med. 2013 Nov;32(5):983-8 |
1 | J:67299 Arikawa-Hirasawa E, Watanabe H, Takami H, Hassell JR, Yamada Y, Perlecan is essential for cartilage and cephalic development. Nat Genet. 1999 Nov;23(3):354-8 |
1* | J:168038 Bimonte S, De Angelis A, Quagliata L, Giusti F, Tammaro R, Dallai R, Ascenzi MG, Diez-Roux G, Franco B, Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol. 2011 Jan 15;349(2):179-91 |
1* | J:237308 Biosse Duplan M, Komla-Ebri D, Heuze Y, Estibals V, Gaudas E, Kaci N, Benoist-Lasselin C, Zerah M, Kramer I, Kneissel M, Porta DG, Di Rocco F, Legeai-Mallet L, Meckel's and condylar cartilages anomalies in achondroplasia result in defective development and growth of the mandible. Hum Mol Genet. 2016 Jul 15;25(14):2997-3010 |
1 | J:188176 Caparros-Martin JA, Valencia M, Reytor E, Pacheco M, Fernandez M, Perez-Aytes A, Gean E, Lapunzina P, Peters H, Goodship JA, Ruiz-Perez VL, The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia. Hum Mol Genet. 2013 Jan 1;22(1):124-39 |
1 | J:210100 Di Rocco F, Biosse Duplan M, Heuze Y, Kaci N, Komla-Ebri D, Munnich A, Mugniery E, Benoist-Lasselin C, Legeai-Mallet L, FGFR3 mutation causes abnormal membranous ossification in achondroplasia. Hum Mol Genet. 2014 Jun 1;23(11):2914-25 |
1 | J:230611 Dierker T, Bachvarova V, Krause Y, Li JP, Kjellen L, Seidler DG, Vortkamp A, Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones. Matrix Biol. 2016 Jan;49:82-92 |
1 | J:101176 Grieshammer U, Cebrian C, Ilagan R, Meyers E, Herzlinger D, Martin GR, FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons. Development. 2005 Sep;132(17):3847-57 |
1 | J:93900 Hasegawa H, Ashigaki S, Takamatsu M, Suzuki-Migishima R, Ohbayashi N, Itoh N, Takada S, Tanabe Y, Laminar patterning in the developing neocortex by temporally coordinated fibroblast growth factor signaling. J Neurosci. 2004 Oct 6;24(40):8711-9 |
1 | J:117235 Hayashi T, Cunningham D, Bermingham-McDonogh O, Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti. Dev Dyn. 2007 Feb;236(2):525-33 |
1* | J:156926 Hayashi T, Ray CA, Younkins C, Bermingham-McDonogh O, Expression patterns of FGF receptors in the developing mammalian cochlea. Dev Dyn. 2010 Feb 3;239(3):1019-1026 |
1* | J:280430 Janeckova E, Feng J, Li J, Rodriguez G, Chai Y, Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development. PLoS One. 2019;14(10):e0223879 |
1* | J:61352 Johnson D, Iseki S, Wilkie AO, Morriss-Kay GM, Expression patterns of Twist and Fgfr1, -2 and -3 in the developing mouse coronal suture suggest a key role for twist in suture initiation and biogenesis. Mech Dev. 2000 Mar 1;91(1-2):341-5 |
1 | J:102948 Koziel L, Wuelling M, Schneider S, Vortkamp A, Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation. Development. 2005 Dec;132(23):5249-60 |
1 | J:233640 Kyrylkova K, Iwaniec UT, Philbrick KA, Leid M, BCL11B regulates sutural patency in the mouse craniofacial skeleton. Dev Biol. 2016 Jul 15;415(2):251-60 |
1 | J:218941 Meier F, Giesert F, Delic S, Faus-Kessler T, Matheus F, Simeone A, Holter SM, Kuhn R, Weisenhorn DM, Wurst W, Prakash N, FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS One. 2014;9(7):e101124 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:205339 Mis EK, Liem KF Jr, Kong Y, Schwartz NB, Domowicz M, Weatherbee SD, Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length. Dev Biol. 2014 Jan 1;385(1):67-82 |
1* | J:85765 Nakajima A, Shimizu S, Moriya H, Yamazaki M, Expression of fibroblast growth factor receptor-3 (FGFR3), signal transducer and activator of transcription-1, and cyclin-dependent kinase inhibitor p21 during endochondral ossification: differential role of FGFR3 in skeletal development and fracture repair. Endocrinology. 2003 Oct;144(10):4659-68 |
1 | J:242339 Ohayon D, Garces A, Joly W, Soukkarieh C, Takagi T, Sabourin JC, Agius E, Darling DS, De Santa Barbara P, Higashi Y, Stolt CC, Hugnot JP, Richardson WD, Carroll P, Pattyn A, Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Cell Rep. 2016 Nov 01;17(6):1473-1481 |
1 | J:75880 Ohbayashi N, Shibayama M, Kurotaki Y, Imanishi M, Fujimori T, Itoh N, Takada S, FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev. 2002 Apr 1;16(7):870-9 |
1 | J:131109 Ohkubo Y, Uchida AO, Shin D, Partanen J, Vaccarino FM, Fibroblast growth factor receptor 1 is required for the proliferation of hippocampal progenitor cells and for hippocampal growth in mouse. J Neurosci. 2004 Jul 7;24(27):6057-69 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
2* | J:3825 Peters K, Ornitz D, Werner S, Williams L, Unique expression pattern of the FGF receptor 3 gene during mouse organogenesis. Dev Biol. 1993 Feb;155(2):423-30 |
1 | J:78879 Pirvola U, Ylikoski J, Trokovic R, Hebert JM, McConnell SK, Partanen J, FGFR1 is required for the development of the auditory sensory epithelium. Neuron. 2002 Aug 15;35(4):671-80 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:356701 Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD, Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr;91(4):387-93 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1 | J:76480 Robledo RF, Rajan L, Li X, Lufkin T, The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev. 2002 May 1;16(9):1089-101 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1 | J:124105 Ruiz-Perez VL, Blair HJ, Rodriguez-Andres ME, Blanco MJ, Wilson A, Liu YN, Miles C, Peters H, Goodship JA, Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. Development. 2007 Aug;134(16):2903-12 |
1* | J:143455 Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Al Awqati Q, Ballabio A, Karsenty G, Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification. Genes Dev. 2008 Oct 1;22(19):2645-50 |
1 | J:154601 Seuntjens E, Nityanandam A, Miquelajauregui A, Debruyn J, Stryjewska A, Goebbels S, Nave KA, Huylebroeck D, Tarabykin V, Sip1 regulates sequential fate decisions by feedback signaling from postmitotic neurons to progenitors. Nat Neurosci. 2009 Nov;12(11):1373-80 |
1 | J:236733 Shibuya M, Ikari T, Sugiyama G, Ohyama Y, Kumamaru W, Nagano K, Sugiura T, Shirasuna K, Mori Y, Efficient regulation of branching morphogenesis via fibroblast growth factor receptor 2c in early-stage embryonic mouse salivary glands. Differentiation. 2016 Oct - Nov;92(4):216-224 |
2 | J:187998 Shung CY, Ota S, Zhou ZQ, Keene DR, Hurlin PJ, Disruption of a Sox9-beta-catenin circuit by mutant Fgfr3 in thanatophoric dysplasia type II. Hum Mol Genet. 2012 Nov 1;21(21):4628-44 |
1* | J:80666 Smits P, Li P, Mandel J, Zhang Z, Deng JM, Behringer RR, de Croumbrugghe B, Lefebvre V, The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001 Aug;1(2):277-90 |
1 | J:84301 Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M, The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 2003 Jul 1;17(13):1677-89 |
1 | J:275375 Sun S, Zhu XJ, Huang H, Guo W, Tang T, Xie B, Xu X, Zhang Z, Shen Y, Dai ZM, Qiu M, WNT signaling represses astrogliogenesis via Ngn2-dependent direct suppression of astrocyte gene expression. Glia. 2019 Jul;67(7):1333-1343 |
1 | J:149459 Wuelling M, Kaiser FJ, Buelens LA, Braunholz D, Shivdasani RA, Depping R, Vortkamp A, Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. Dev Biol. 2009 Apr 1;328(1):40-53 |
1 | J:281388 Xu J, Huang Z, Wang W, Tan X, Li H, Zhang Y, Tian W, Hu T, Chen YP, FGF8 Signaling Alters the Osteogenic Cell Fate in the Hard Palate. J Dent Res. 2018 May;97(5):589-596 |
2* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
1 | J:223471 Zhao X, Chen Y, Zhu Q, Huang H, Teng P, Zheng K, Hu X, Xie B, Zhang Z, Sander M, Qiu M, Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor. PLoS One. 2014;9(10):e109171 |
1 | J:172282 Zhou ZQ, Shung CY, Ota S, Akiyama H, Keene DR, Hurlin PJ, Sequential and coordinated actions of c-Myc and N-Myc control appendicular skeletal development. PLoS One. 2011;6(4):e18795 |
Fgfr4 fibroblast growth factor receptor 4 (Synonyms: Fgfr-4) | |
Results | Reference |
1 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1* | J:203801 Amann R, Trueb B, Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1. Int J Mol Med. 2013 Nov;32(5):983-8 |
1 | J:101176 Grieshammer U, Cebrian C, Ilagan R, Meyers E, Herzlinger D, Martin GR, FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons. Development. 2005 Sep;132(17):3847-57 |
1 | J:184019 Han D, Zhao H, Parada C, Hacia JG, Bringas P Jr, Chai Y, A TGFbeta-Smad4-Fgf6 signaling cascade controls myogenic differentiation and myoblast fusion during tongue development. Development. 2012 May;139(9):1640-50 |
1 | J:137155 Hayashi T, Ray CA, Bermingham-McDonogh O, Fgf20 is required for sensory epithelial specification in the developing cochlea. J Neurosci. 2008 Jun 4;28(23):5991-9 |
1* | J:156926 Hayashi T, Ray CA, Younkins C, Bermingham-McDonogh O, Expression patterns of FGF receptors in the developing mammalian cochlea. Dev Dyn. 2010 Feb 3;239(3):1019-1026 |
1* | J:280430 Janeckova E, Feng J, Li J, Rodriguez G, Chai Y, Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development. PLoS One. 2019;14(10):e0223879 |
2 | J:2028 Korhonen J, Partanen J, Alitalo K, Expression of FGFR-4 mRNA in developing mouse tissues. Int J Dev Biol. 1992 Jun;36(2):323-9 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:356701 Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD, Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr;91(4):387-93 |
1 | J:236733 Shibuya M, Ikari T, Sugiyama G, Ohyama Y, Kumamaru W, Nagano K, Sugiura T, Shirasuna K, Mori Y, Efficient regulation of branching morphogenesis via fibroblast growth factor receptor 2c in early-stage embryonic mouse salivary glands. Differentiation. 2016 Oct - Nov;92(4):216-224 |
1* | J:11593 Stark KL, McMahon JA, McMahon AP, FGFR-4, a new member of the fibroblast growth factor receptor family, expressed in the definitive endoderm and skeletal muscle lineages of the mouse. Development. 1991 Oct;113(2):641-51 |
1 | J:281388 Xu J, Huang Z, Wang W, Tan X, Li H, Zhang Y, Tian W, Hu T, Chen YP, FGF8 Signaling Alters the Osteogenic Cell Fate in the Hard Palate. J Dent Res. 2018 May;97(5):589-596 |
2* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
Fgfrl1 fibroblast growth factor receptor-like 1 (Synonyms: FGFR5, FGFR5beta, FGFR5gamma, fibroblast growth factor receptor 5) | |
Results | Reference |
1* | J:203801 Amann R, Trueb B, Evidence that the novel receptor FGFRL1 signals indirectly via FGFR1. Int J Mol Med. 2013 Nov;32(5):983-8 |
2* | J:216142 Amann R, Wyder S, Slavotinek AM, Trueb B, The FgfrL1 receptor is required for development of slow muscle fibers. Dev Biol. 2014 Oct 15;394(2):228-41 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1 | J:153202 Gerber SD, Steinberg F, Beyeler M, Villiger PM, Trueb B, The murine Fgfrl1 receptor is essential for the development of the metanephric kidney. Dev Biol. 2009 Nov 1;335(1):106-19 |
1* | J:150712 Yaguchi Y, Yu T, Ahmed MU, Berry M, Mason I, Basson MA, Fibroblast growth factor (FGF) gene expression in the developing cerebellum suggests multiple roles for FGF signaling during cerebellar morphogenesis and development. Dev Dyn. 2009 Jun 19;238(8):2058-2072 |
Fgg fibrinogen gamma chain (Synonyms: 3010002H13Rik, gamma-fibrinogen) | |
Results | Reference |
1* | J:65092 Ishiguro K, Kojima T, Kadomatsu K, Nakayama Y, Takagi A, Suzuki M, Takeda N, Ito M, Yamamoto K, Matsushita T, Kusugami K, Muramatsu T, Saito H, Complete antithrombin deficiency in mice results in embryonic lethality. J Clin Invest. 2000 Oct;106(7):873-8 |
Fgr FGR proto-oncogene, Src family tyrosine kinase (Synonyms: Ali18, Mhdaali18) | |
Results | Reference |
1* | J:55945 Wang JP, Chuang SM, Shen CL, Chen ST, Expression of Src family during development of the mouse nervous system. Biomed Res. 1998 OCT;19(5):315-325 |
Fh1 fumarate hydratase 1 (Synonyms: fumarase) | |
Results | Reference |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
Fhl1 four and a half LIM domains 1 (Synonyms: KyoT, KyoT1, KyoT2) | |
Results | Reference |
1* | J:120114 Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY, A biphasic pattern of gene expression during mouse retina development. BMC Dev Biol. 2006;6:48 |
Fhl2 four and a half LIM domains 2 (Synonyms: SLIM3) | |
Results | Reference |
1* | J:313274 Du J, Wang Q, Wang L, Wang X, Yang P, The expression pattern of FHL2 during mouse molar development. J Mol Histol. 2012 Jun;43(3):289-95 |
1* | J:317089 Du J, Wang Q, Yang P, Wang X, FHL2 mediates tooth development and human dental pulp cell differentiation into odontoblasts, partially by interacting with Runx2. J Mol Histol. 2016 Apr;47(2):195-202 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Fhod3 formin homology 2 domain containing 3 (Synonyms: A930009H06Rik) | |
Results | Reference |
1* | J:249143 Fujimoto N, Kan-O M, Ushijima T, Kage Y, Tominaga R, Sumimoto H, Takeya R, Transgenic Expression of the Formin Protein Fhod3 Selectively in the Embryonic Heart: Role of Actin-Binding Activity of Fhod3 and Its Sarcomeric Localization during Myofibrillogenesis. PLoS One. 2016;11(2):e0148472 |
1 | J:256068 Ushijima T, Fujimoto N, Matsuyama S, Kan-O M, Kiyonari H, Shioi G, Kage Y, Yamasaki S, Takeya R, Sumimoto H, The actin-organizing formin protein Fhod3 is required for postnatal development and functional maintenance of the adult heart in mice. J Biol Chem. 2018 Jan 5;293(1):148-162 |
Figla folliculogenesis specific basic helix-loop-helix (Synonyms: bHLHc8, FIG alpha) | |
Results | Reference |
1 | J:297097 Sorrenti M, Klinger FG, Iona S, Rossi V, Marcozzi S, DE Felici M, Expression and possible roles of extracellular signal-related kinases 1-2 (ERK1-2) in mouse primordial germ cell development. J Reprod Dev. 2020 Oct 13;66(5):399-409 |
Fign fidgetin (Synonyms: Fgn) | |
Results | Reference |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Filip1 filamin A interacting protein 1 (Synonyms: 5730485H21Rik, FILIP) | |
Results | Reference |
1* | J:260692 Yagi H, Nagano T, Xie MJ, Ikeda H, Kuroda K, Komada M, Iguchi T, Tariqur RM, Morikubo S, Noguchi K, Murase K, Okabe M, Sato M, Filamin A-interacting protein (FILIP) is a region-specific modulator of myosin 2b and controls spine morphology and NMDA receptor accumulation. Sci Rep. 2014 Sep 15;4:6353 |
Fis1 fission, mitochondrial 1 (Synonyms: 2010003O14Rik, Ttc11) | |
Results | Reference |
1 | J:333326 Suh J, Kim NK, Shim W, Lee SH, Kim HJ, Moon E, Sesaki H, Jang JH, Kim JE, Lee YS, Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab. 2023 Feb 7;35(2):345-360.e7 |
Fjx1 four jointed box 1 | |
Results | Reference |
1 | J:102280 Rock R, Heinrich AC, Schumacher N, Gessler M, Fjx1: a notch-inducible secreted ligand with specific binding sites in developing mouse embryos and adult brain. Dev Dyn. 2005 Nov;234(3):602-12 |
1 | J:138247 Saburi S, Hester I, Fischer E, Pontoglio M, Eremina V, Gessler M, Quaggin SE, Harrison R, Mount R, McNeill H, Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nat Genet. 2008 Aug;40(8):1010-5 |
Fkbp1b FK506 binding protein 1b (Synonyms: 12.6kDa, calstabin2, FKBP12.6) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Fkbp2 FK506 binding protein 2 (Synonyms: 13kDa, mFKBP13, mFKBP2) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Fkbp5 FK506 binding protein 5 (Synonyms: D17Ertd592e, Dit1, FKBP51) | |
Results | Reference |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
2* | J:306453 Kajioka D, Suzuki K, Matsushita S, Hino S, Sato T, Takada S, Isono K, Takeo T, Kajimoto M, Nakagata N, Nakao M, Suyama M, DeFalco T, Miyagawa S, Yamada G, Sexual fate of murine external genitalia development: Conserved transcriptional competency for male-biased genes in both sexes. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2024067118 |
Fkbp6 FK506 binding protein 6 (Synonyms: 1700008G22Rik, D5Ertd724e) | |
Results | Reference |
1* | J:316637 Strogantsev R, Krueger F, Yamazawa K, Shi H, Gould P, Goldman-Roberts M, McEwen K, Sun B, Pedersen R, Ferguson-Smith AC, Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression. Genome Biol. 2015 May 30;16:112 |
Fkbp7 FK506 binding protein 7 (Synonyms: FKBP23) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Fktn fukutin (Synonyms: Fcmd, Fukutin) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
Flg filaggrin (Synonyms: fillagrin, ft, profilaggrin) | |
Results | Reference |
1 | J:233601 Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP, Harwood CA, Byrne C, O'Shaughnessy RF, Bergamaschi D, Constitutive Autophagy and Nucleophagy during Epidermal Differentiation. J Invest Dermatol. 2016 Jul;136(7):1460-70 |
1 | J:141601 Bayo P, Sanchis A, Bravo A, Cascallana JL, Buder K, Tuckermann J, Schutz G, Perez P, Glucocorticoid receptor is required for skin barrier competence. Endocrinology. 2008 Mar;149(3):1377-88 |
1 | J:272608 Cohen I, Zhao D, Menon G, Nakayama M, Koseki H, Zheng D, Ezhkova E, PRC1 preserves epidermal tissue integrity independently of PRC2. Genes Dev. 2019 Jan 1;33(1-2):55-60 |
1* | J:129949 Cui CY, Kunisada M, Esibizione D, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet. 2007 Nov 1;16(21):2583-90 |
1 | J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39 |
2* | J:103134 Fischer H, Rossiter H, Ghannadan M, Jaeger K, Barresi C, Declercq W, Tschachler E, Eckhart L, Caspase-14 but not caspase-3 is processed during the development of fetal mouse epidermis. Differentiation. 2005 Oct;73(8):406-13 |
1* | J:136080 Guttormsen J, Koster MI, Stevens JR, Roop DR, Williams T, Winger QA, Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice. Dev Biol. 2008 May 1;317(1):187-95 |
1* | J:180909 Hoste E, Kemperman P, Devos M, Denecker G, Kezic S, Yau N, Gilbert B, Lippens S, De Groote P, Roelandt R, Van Damme P, Gevaert K, Presland RB, Takahara H, Puppels G, Caspers P, Vandenabeele P, Declercq W, Caspase-14 is required for filaggrin degradation to natural moisturizing factors in the skin. J Invest Dermatol. 2011 Nov;131(11):2233-41 |
2 | J:83259 Jaubert J, Cheng J, Segre JA, Ectopic expression of kruppel like factor 4 (Klf4) accelerates formation of the epidermal permeability barrier. Development. 2003 Jun;130(12):2767-77 |
2* | J:73258 Makino T, Takaishi M, Morohashi M, Huh NH, Hornerin, a novel profilaggrin-like protein and differentiation-specific marker isolated from mouse skin. J Biol Chem. 2001 Dec 14;276(50):47445-52 |
1 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
2 | J:279389 Miao Q, Hill MC, Chen F, Mo Q, Ku AT, Ramos C, Sock E, Lefebvre V, Nguyen H, SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair. Nat Commun. 2019 Sep 6;10(1):4042 |
2 | J:122775 O'Shaughnessy RF, Welti JC, Cooke JC, Avilion AA, Monks B, Birnbaum MJ, Byrne C, AKT-dependent HspB1 (Hsp27) activity in epidermal differentiation. J Biol Chem. 2007 Jun 8;282(23):17297-305 |
1 | J:153617 O'Shaughnessy RF, Welti JC, Sully K, Byrne C, Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development. Development. 2009 Oct;136(20):3423-31 |
1 | J:192725 Okano J, Lichti U, Mamiya S, Aronova M, Zhang G, Yuspa SH, Hamada H, Sakai Y, Morasso MI, Increased retinoic acid levels through ablation of Cyp26b1 determine the processes of embryonic skin barrier formation and peridermal development. J Cell Sci. 2012 Apr 1;125(Pt 7):1827-36 |
1 | J:171374 Osorio KM, Lilja KC, Tumbar T, Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol. 2011 Apr 4;193(1):235-50 |
1 | J:196491 Torchia EC, Zhang L, Huebner AJ, Sen S, Roop DR, Aurora kinase-A deficiency during skin development impairs cell division and stratification. J Invest Dermatol. 2013 Jan;133(1):78-86 |
1 | J:114626 Yu Z, Lin KK, Bhandari A, Spencer JA, Xu X, Wang N, Lu Z, Gill GN, Roop DR, Wertz P, Andersen B, The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Dev Biol. 2006 Nov 1;299(1):122-36 |
2 | J:225082 Zhang LJ, Bhattacharya S, Leid M, Ganguli-Indra G, Indra AK, Ctip2 is a dynamic regulator of epidermal proliferation and differentiation by integrating EGFR and Notch signaling. J Cell Sci. 2012 Dec 1;125(Pt 23):5733-44 |
Fli1 Friend leukemia integration 1 (Synonyms: EWSR2, Fli-1, Sic1, SIC-1) | |
Results | Reference |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Flna filamin, alpha (Synonyms: ABP-280, actin-binding protein 280, Dilp2, F730004A14Rik, filamin-1, Fln1, GENA 379) | |
Results | Reference |
1 | J:125095 Lu J, Lian G, Lenkinski R, De Grand A, Vaid RR, Bryce T, Stasenko M, Boskey A, Walsh C, Sheen V, Filamin B mutations cause chondrocyte defects in skeletal development. Hum Mol Genet. 2007 Jul 15;16(14):1661-75 |
1* | J:117267 Sarkisian MR, Bartley CM, Chi H, Nakamura F, Hashimoto-Torii K, Torii M, Flavell RA, Rakic P, MEKK4 signaling regulates filamin expression and neuronal migration. Neuron. 2006 Dec 7;52(5):789-801 |
1 | J:79977 Sheen VL, Feng Y, Graham D, Takafuta T, Shapiro SS, Walsh CA, Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact. Hum Mol Genet. 2002 Nov 1;11(23):2845-54 |
2 | J:187673 Zhang J, Neal J, Lian G, Shi B, Ferland RJ, Sheen V, Brefeldin A-inhibited Guanine Exchange Factor 2 Regulates Filamin A Phosphorylation and Neuronal Migration. J Neurosci. 2012 Sep 5;32(36):12619-29 |
Flnb filamin, beta | |
Results | Reference |
1 | J:125095 Lu J, Lian G, Lenkinski R, De Grand A, Vaid RR, Bryce T, Stasenko M, Boskey A, Walsh C, Sheen V, Filamin B mutations cause chondrocyte defects in skeletal development. Hum Mol Genet. 2007 Jul 15;16(14):1661-75 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1* | J:117267 Sarkisian MR, Bartley CM, Chi H, Nakamura F, Hashimoto-Torii K, Torii M, Flavell RA, Rakic P, MEKK4 signaling regulates filamin expression and neuronal migration. Neuron. 2006 Dec 7;52(5):789-801 |
1 | J:79977 Sheen VL, Feng Y, Graham D, Takafuta T, Shapiro SS, Walsh CA, Filamin A and Filamin B are co-expressed within neurons during periods of neuronal migration and can physically interact. Hum Mol Genet. 2002 Nov 1;11(23):2845-54 |
Flnc filamin C, gamma (Synonyms: 1110055E19Rik, actin binding protein 280, Fln2) | |
Results | Reference |
1* | J:59239 Chiang W, Greaser ML, Lyons GE, Filamin isogene expression during mouse myogenesis. Dev Dyn. 2000 Jan;217(1):99-108 |
Flrt2 fibronectin leucine rich transmembrane protein 2 | |
Results | Reference |
2 | J:171515 Muller PS, Schulz R, Maretto S, Costello I, Srinivas S, Bikoff E, Robertson E, The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis. Development. 2011 Apr;138(7):1297-308 |
Flrt3 fibronectin leucine rich transmembrane protein 3 (Synonyms: 5530600M07Rik, C430047I10Rik, mKIAA1469) | |
Results | Reference |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
1 | J:171515 Muller PS, Schulz R, Maretto S, Costello I, Srinivas S, Bikoff E, Robertson E, The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis. Development. 2011 Apr;138(7):1297-308 |
1 | J:343098 Zhou Z, Pan Y, Zhou S, Wang S, Zhang D, Cao Y, Jiang X, Li J, Zhu L, Zhao L, Gu S, Lin G, Dong Z, Sun HX, Single-cell analysis reveals specific neuronal transition during mouse corticogenesis. Front Cell Dev Biol. 2023;11:1209320 |
Flt1 FMS-like tyrosine kinase 1 (Synonyms: Flt-1, sFlt1, vascular endothelial growth factor receptor-1, VEGFR-1, VEGFR1) | |
Results | Reference |
1 | J:71816 Ayadi A, Zheng H, Sobieszczuk P, Buchwalter G, Moerman P, Alitalo K, Wasylyk B, Net-targeted mutant mice develop a vascular phenotype and up-regulate egr-1. EMBO J. 2001 Sep 17;20(18):5139-52 |
3 | J:54038 He Y, Smith SK, Day KA, Clark DE, Licence DR, Charnock-Jones DS, Alternative splicing of vascular endothelial growth factor (VEGF)-R1 (FLT-1) pre-mRNA is important for the regulation of VEGF activity. Mol Endocrinol. 1999 Apr;13(4):537-45 |
1 | J:122952 Hung IH, Yu K, Lavine KJ, Ornitz DM, FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. Dev Biol. 2007 Jul 15;307(2):300-13 |
1* | J:258542 Hupe M, Li MX, Kneitz S, Davydova D, Yokota C, Kele-Olovsson J, Hot B, Stenman JM, Gessler M, Gene expression profiles of brain endothelial cells during embryonic development at bulk and single-cell levels. Sci Signal. 2017 Jul 11;10(487) |
1 | J:199291 Jiang M, Ku WY, Fu J, Offermanns S, Hsu W, Que J, Gpr177 regulates pulmonary vasculature development. Development. 2013 Sep;140(17):3589-94 |
1 | J:119882 Liu Z, Lavine KJ, Hung IH, Ornitz DM, FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate. Dev Biol. 2007 Feb 1;302(1):80-91 |
1* | J:231234 Luna RL, Kay VR, Ratsep MT, Khalaj K, Bidarimath M, Peterson N, Carmeliet P, Jin A, Croy BA, Placental growth factor deficiency is associated with impaired cerebral vascular development in mice. Mol Hum Reprod. 2016 Feb;22(2):130-42 |
1* | J:74493 Maes C, Carmeliet P, Moermans K, Stockmans I, Smets N, Collen D, Bouillon R, Carmeliet G, Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF(164) and VEGF(188). Mech Dev. 2002 Feb;111(1-2):61-73 |
1 | J:174102 Matsubara S, Takahashi T, Kimura AP, Localization and subcellular distribution of prolyl oligopeptidase in the mouse placenta. J Mol Histol. 2011 Jun;42(3):251-64 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
1 | J:150308 Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009 May 1;182(9):5439-45 |
1 | J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34 |
1* | J:75934 Zelzer E, McLean W, Ng YS, Fukai N, Reginato AM, Lovejoy S, D'Amore PA, Olsen BR, Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development. 2002 Apr;129(8):1893-904 |
1* | J:99650 Zhao L, Wang K, Ferrara N, Vu TH, Vascular endothelial growth factor co-ordinates proper development of lung epithelium and vasculature. Mech Dev. 2005 Jul-Aug;122(7-8):877-86 |
Flt3 FMS-like tyrosine kinase 3 (Synonyms: CD135, Flk-2, Flk2, Flt-3, wmfl) | |
Results | Reference |
1 | J:26783 deLapeyriere O, Naquet P, Planche J, Marchetto S, Rottapel R, Gambarelli D, Rosnet O, Birnbaum D, Expression of Flt3 tyrosine kinase receptor gene in mouse hematopoietic and nervous tissues. Differentiation. 1995 Jun;58(5):351-9 |
Flt4 FMS-like tyrosine kinase 4 (Synonyms: Flt-4, VEGFR-3, VEGFR3) | |
Results | Reference |
1 | J:71816 Ayadi A, Zheng H, Sobieszczuk P, Buchwalter G, Moerman P, Alitalo K, Wasylyk B, Net-targeted mutant mice develop a vascular phenotype and up-regulate egr-1. EMBO J. 2001 Sep 17;20(18):5139-52 |
1 | J:152968 Bazigou E, Xie S, Chen C, Weston A, Miura N, Sorokin L, Adams R, Muro AF, Sheppard D, Makinen T, Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis. Dev Cell. 2009 Aug;17(2):175-86 |
1 | J:344154 Carlantoni C, Liekfeld LMH, Hemkemeyer SA, Schreier D, Saygi C, Kurelic R, Cardarelli S, Kalucka J, Schulte C, Beerens M, Mailer RK, Schaffer TE, Naro F, Pellegrini M, Nikolaev VO, Renne T, Frye M, The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling. Dev Cell. 2023 Dec 23; |
1 | J:233304 Cha B, Geng X, Mahamud MR, Fu J, Mukherjee A, Kim Y, Jho EH, Kim TH, Kahn ML, Xia L, Dixon JB, Chen H, Srinivasan RS, Mechanotransduction activates canonical Wnt/beta-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves. Genes Dev. 2016 Jun 15;30(12):1454-69 |
2 | J:269779 Cha B, Geng X, Mahamud MR, Zhang JY, Chen L, Kim W, Jho EH, Kim Y, Choi D, Dixon JB, Chen H, Hong YK, Olson L, Kim TH, Merrill BJ, Davis MJ, Srinivasan RS, Complementary Wnt Sources Regulate Lymphatic Vascular Development via PROX1-Dependent Wnt/beta-Catenin Signaling. Cell Rep. 2018 Oct 16;25(3):571-584.e5 |
1 | J:301556 Cha B, Ho YC, Geng X, Mahamud MR, Chen L, Kim Y, Choi D, Kim TH, Randolph GJ, Cao X, Chen H, Srinivasan RS, YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling. Development. 2020 Dec 13;147(23):dev195453 |
1 | J:289355 Cho H, Kim J, Ahn JH, Hong YK, Makinen T, Lim DS, Koh GY, YAP and TAZ Negatively Regulate Prox1 During Developmental and Pathologic Lymphangiogenesis. Circ Res. 2019 Jan 18;124(2):225-242 |
1 | J:159507 D'Amico G, Korhonen EA, Waltari M, Saharinen P, Laakkonen P, Alitalo K, Loss of endothelial Tie1 receptor impairs lymphatic vessel development-brief report. Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):207-9 |
1 | J:93150 Dagenais SL, Hartsough RL, Erickson RP, Witte MH, Butler MG, Glover TW, Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome. Gene Expr Patterns. 2004 Oct;4(6):611-9 |
1 | J:359863 Do LNH, Delgado E, Lim CG, Bkhache M, Peluzzo AM, Hua Y, Oza M, Mohsin S, Chen H, Autieri MV, Kim S, Liu X, A neuro-lymphatic communication guides lymphatic development by CXCL12 and CXCR4 signaling. Development. 2024 Nov 15;151(22) |
1 | J:228882 Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS, Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016 Jan 1;409(1):218-33 |
1 | J:308918 Geng X, Yanagida K, Akwii RG, Choi D, Chen L, Ho Y, Cha B, Mahamud MR, Berman de Ruiz K, Ichise H, Chen H, Wythe JD, Mikelis CM, Hla T, Srinivasan RS, S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling. JCI Insight. 2020 Jul 23;5(14) |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1 | J:363177 Ho YC, Geng X, O'Donnell A, Ibarrola J, Fernandez-Celis A, Varshney R, Subramani K, Azartash-Namin ZJ, Kim J, Silasi R, Wylie-Sears J, Alvandi Z, Chen L, Cha B, Chen H, Xia L, Zhou B, Lupu F, Burkhart HM, Aikawa E, Olson LE, Ahamed J, Lopez-Andres N, Bischoff J, Yutzey KE, Srinivasan RS, PROX1 Inhibits PDGF-B Expression to Prevent Myxomatous Degeneration of Heart Valves. Circ Res. 2023 Sep;133(6):463-480 |
2 | J:302486 Jiang X, Tian W, Granucci EJ, Tu AB, Kim D, Dahms P, Pasupneti S, Peng G, Kim Y, Lim AH, Espinoza FH, Cribb M, Dixon JB, Rockson SG, Semenza GL, Nicolls MR, Decreased lymphatic HIF-2alpha accentuates lymphatic remodeling in lymphedema. J Clin Invest. 2020 Oct 1;130(10):5562-5575 |
1* | J:24352 Kaipainen A, Korhonen J, Mustonen T, van Hinsbergh VW, Fang GH, Dumont D, Breitman M, Alitalo K, Expression of the fms-like tyrosine kinase 4 gene becomes restricted to lymphatic endothelium during development. Proc Natl Acad Sci U S A. 1995 Apr 11;92(8):3566-70 |
1 | J:173649 Kanady JD, Dellinger MT, Munger SJ, Witte MH, Simon AM, Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax. Dev Biol. 2011 Jun 15;354(2):253-66 |
1 | J:87394 Karkkainen MJ, Haiko P, Sainio K, Partanen J, Taipale J, Petrova TV, Jeltsch M, Jackson DG, Talikka M, Rauvala H, Betsholtz C, Alitalo K, Vascular endothelial growth factor C is required for sprouting of the first lymphatic vessels from embryonic veins. Nat Immunol. 2004 Jan;5(1):74-80 |
1* | J:122404 Kim KE, Sung HK, Koh GY, Lymphatic development in mouse small intestine. Dev Dyn. 2007 Jul;236(7):2020-5 |
1 | J:222246 Klotz L, Norman S, Vieira JM, Masters M, Rohling M, Dube KN, Bollini S, Matsuzaki F, Carr CA, Riley PR, Cardiac lymphatics are heterogeneous in origin and respond to injury. Nature. 2015 Jun 4;522(7554):62-7 |
1 | J:342552 Kulikauskas MR, Oatley M, Yu T, Liu Z, Matsumura L, Kidder E, Ruter D, Bautch VL, Endothelial cell SMAD6 balances Alk1 function to regulate adherens junctions and hepatic vascular development. Development. 2023 Nov 1;150(21) |
1 | J:107096 Le Bras B, Barallobre MJ, Homman-Ludiye J, Ny A, Wyns S, Tammela T, Haiko P, Karkkainen MJ, Yuan L, Muriel MP, Chatzopoulou E, Breant C, Zalc B, Carmeliet P, Alitalo K, Eichmann A, Thomas JL, VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain. Nat Neurosci. 2006 Mar;9(3):340-8 |
2 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
1 | J:244674 Liu X, Pasula S, Song H, Tessneer KL, Dong Y, Hahn S, Yago T, Brophy ML, Chang B, Cai X, Wu H, McManus J, Ichise H, Georgescu C, Wren JD, Griffin C, Xia L, Srinivasan RS, Chen H, Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function. Sci Signal. 2014 Oct 14;7(347):ra97 |
2 | J:317975 Lu P, Wang Y, Liu Y, Wang Y, Wu B, Zheng D, Harvey RP, Zhou B, Perinatal angiogenesis from pre-existing coronary vessels via DLL4-NOTCH1 signalling. Nat Cell Biol. 2021 Sep;23(9):967-977 |
1 | J:335167 Lu P, Wu B, Wang Y, Russell M, Liu Y, Bernard DJ, Zheng D, Zhou B, Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis. Dev Cell. 2023 Mar 29; |
1 | J:316476 Ma W, Gil HJ, Liu X, Diebold LP, Morgan MA, Oxendine-Burns MJ, Gao P, Chandel NS, Oliver G, Mitochondrial respiration controls the Prox1-Vegfr3 feedback loop during lymphatic endothelial cell fate specification and maintenance. Sci Adv. 2021 Apr;7(18) |
1 | J:284120 Mahamud MR, Geng X, Ho YC, Cha B, Kim Y, Ma J, Chen L, Myers G, Camper S, Mustacich D, Witte M, Choi D, Hong YK, Chen H, Varshney G, Engel JD, Wang S, Kim TH, Lim KC, Srinivasan RS, GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126. Development. 2019 Nov 5;146(21):dev184218 |
1 | J:329978 Maruyama K, Miyagawa-Tomita S, Haneda Y, Kida M, Matsuzaki F, Imanaka-Yoshida K, Kurihara H, The cardiopharyngeal mesoderm contributes to lymphatic vessel development in mouse. Elife. 2022 Oct 5;11:e81515 |
1* | J:278916 Maruyama K, Miyagawa-Tomita S, Mizukami K, Matsuzaki F, Kurihara H, Isl1-expressing non-venous cell lineage contributes to cardiac lymphatic vessel development. Dev Biol. 2019 Aug 15;452(2):134-143 |
1 | J:306872 Maruyama K, Naemura K, Arima Y, Uchijima Y, Nagao H, Yoshihara K, Singh MK, Uemura A, Matsuzaki F, Yoshida Y, Kurihara Y, Miyagawa-Tomita S, Kurihara H, Semaphorin3E-PlexinD1 signaling in coronary artery and lymphatic vessel development with clinical implications in myocardial recovery. iScience. 2021 Apr 23;24(4):102305 |
1 | J:324254 Muley A, Kim Uh M, Salazar-De Simone G, Swaminathan B, James JM, Murtomaki A, Youn SW, McCarron JD, Kitajewski C, Gnarra Buethe M, Riitano G, Mukouyama YS, Kitajewski J, Shawber CJ, Unique functions for Notch4 in murine embryonic lymphangiogenesis. Angiogenesis. 2022 May;25(2):205-224 |
1 | J:231667 Munger SJ, Geng X, Srinivasan RS, Witte MH, Paul DL, Simon AM, Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice. Dev Biol. 2016 Apr 15;412(2):173-90 |
1 | J:275825 Norman TA Jr, Gower AC, Chen F, Fine A, Transcriptional landscape of pulmonary lymphatic endothelial cells during fetal gestation. PLoS One. 2019;14(5):e0216795 |
1 | J:149138 Norrmen C, Ivanov KI, Cheng J, Zangger N, Delorenzi M, Jaquet M, Miura N, Puolakkainen P, Horsley V, Hu J, Augustin HG, Yla-Herttuala S, Alitalo K, Petrova TV, FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1. J Cell Biol. 2009 May 4;185(3):439-57 |
1 | J:158668 Qu X, Tompkins K, Batts LE, Puri M, Baldwin S, Abnormal embryonic lymphatic vessel development in Tie1 hypomorphic mice. Development. 2010 Apr;137(8):1285-95 |
1 | J:181330 Sabine A, Agalarov Y, Maby-El Hajjami H, Jaquet M, Hagerling R, Pollmann C, Bebber D, Pfenniger A, Miura N, Dormond O, Calmes JM, Adams RH, Makinen T, Kiefer F, Kwak BR, Petrova TV, Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation. Dev Cell. 2012 Feb 14;22(2):430-45 |
1 | J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34 |
1 | J:237534 Wang Y, Baeyens N, Corti F, Tanaka K, Fang JS, Zhang J, Jin Y, Coon B, Hirschi KK, Schwartz MA, Simons M, Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development. Development. 2016 Dec 01;143(23):4441-4451 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:244845 Wong BW, Wang X, Zecchin A, Thienpont B, Cornelissen I, Kalucka J, Garcia-Caballero M, Missiaen R, Huang H, Bruning U, Blacher S, Vinckier S, Goveia J, Knobloch M, Zhao H, Dierkes C, Shi C, Hagerling R, Moral-Darde V, Wyns S, Lippens M, Jessberger S, Fendt SM, Luttun A, Noel A, Kiefer F, Ghesquiere B, Moons L, Schoonjans L, Dewerchin M, Eelen G, Lambrechts D, Carmeliet P, The role of fatty acid beta-oxidation in lymphangiogenesis. Nature. 2017 Feb 02;542(7639):49-54 |
1 | J:278463 Yang Y, Cha B, Motawe ZY, Srinivasan RS, Scallan JP, VE-Cadherin Is Required for Lymphatic Valve Formation and Maintenance. Cell Rep. 2019;28(9):2397-2412 |
Flvcr2 feline leukemia virus subgroup C cellular receptor 2 (Synonyms: CCT, Mfsd7c, MGC:19050) | |
Results | Reference |
1 | J:294228 Kalailingam P, Wang KQ, Toh XR, Nguyen TQ, Chandrakanthan M, Hasan Z, Habib C, Schif A, Radio FC, Dallapiccola B, Weiss K, Nguyen LN, Deficiency of MFSD7c results in microcephaly-associated vasculopathy in Fowler syndrome. J Clin Invest. 2020 Aug 3;130(8):4081-4093 |
Fmn1 formin 1 (Synonyms: Fmn, formin-1, ld, limb deformity) | |
Results | Reference |
1 | J:29274 Chan DC, Wynshaw-Boris A, Leder P, Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of fgf-4 and shh in the limb bud. Development. 1995 Oct;121(10):3151-62 |
Fmo2 flavin containing monooxygenase 2 (Synonyms: 2310008D08Rik, 2310042I22Rik, MGC:28212) | |
Results | Reference |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Fmo5 flavin containing monooxygenase 5 (Synonyms: 5033418D19Rik) | |
Results | Reference |
1* | J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903 |
Fmod fibromodulin (Synonyms: SLRR2E) | |
Results | Reference |
1 | J:335626 Castillo V, Diaz-Astudillo P, Corrales-Orovio R, San Martin S, Egana JT, Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin. Cells. 2023 Apr 22;12(9) |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:74145 Gori F, Schipani E, Demay MB, Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development. J Cell Biochem. 2001 Apr 2-27;82(1):46-57 |
1 | J:175747 Liu W, Watson SS, Lan Y, Keene DR, Ovitt CE, Liu H, Schweitzer R, Jiang R, The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis. Mol Cell Biol. 2010 Oct;30(20):4797-807 |
1 | J:193853 Makino Y, Takahashi Y, Tanabe R, Tamamura Y, Watanabe T, Haraikawa M, Hamagaki M, Hata K, Kanno J, Yoneda T, Saga Y, Goseki-Sone M, Kaneko K, Yamaguchi A, Iimura T, Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone. 2013 Mar;53(1):248-58 |
Fmr1 fragile X messenger ribonucleoprotein 1 (Synonyms: Fmr-1, FMRP, fragile X mental retardation 1) | |
Results | Reference |
2 | J:16233 Bachner D, Manca A, Steinbach P, Wohrle D, Just W, Vogel W, Hameister H, Poustka A, Enhanced expression of the murine FMR1 gene during germ cell proliferation suggests a special function in both the male and the female gonad. Hum Mol Genet. 1993 Dec;2(12):2043-50 |
1 | J:330390 Gura MA, Relovska S, Abt KM, Seymour KA, Wu T, Kaya H, Turner JMA, Fazzio TG, Freiman RN, TAF4b transcription networks regulating early oocyte differentiation. Development. 2022 Feb 1;149(3):dev200074 |
Fn1 fibronectin 1 (Synonyms: Fn, Fn-1) | |
Results | Reference |
1 | J:33496 Akhurst RJ, Lehnert SA, Faissner A, Duffie E, TGF beta in murine morphogenetic processes: the early embryo and cardiogenesis. Development. 1990 Apr;108(4):645-56 |
1 | J:331894 Alcantara MC, Suzuki K, Acebedo AR, Kajioka D, Hirohata S, Kaisho T, Hatano Y, Yamagata K, Takahashi S, Yamada G, Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice. iScience. 2022 Dec 22;25(12):105609 |
2 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
1* | J:152889 Aufderheide E, Chiquet-Ehrismann R, Ekblom P, Epithelial-mesenchymal interactions in the developing kidney lead to expression of tenascin in the mesenchyme. J Cell Biol. 1987 Jul;105(1):599-608 |
1 | J:237340 Ben Shoham A, Rot C, Stern T, Krief S, Akiva A, Dadosh T, Sabany H, Lu Y, Kadler KE, Zelzer E, Deposition of collagen type I onto skeletal endothelium reveals a new role for blood vessels in regulating bone morphology. Development. 2016 Nov 01;143(21):3933-3943 |
1 | J:267108 Cho E, Mysliwiec MR, Carlson CD, Ansari A, Schwartz RJ, Lee Y, Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development. J Biol Chem. 2018 Jul 27;293(30):11659-11673 |
1 | J:236425 Clay H, Wilsbacher LD, Wilson SJ, Duong DN, McDonald M, Lam I, Park KE, Chun J, Coughlin SR, Sphingosine 1-phosphate receptor-1 in cardiomyocytes is required for normal cardiac development. Dev Biol. 2016 Oct 1;418(1):157-65 |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1 | J:353622 Dinesh NEH, Baratang N, Rosseau J, Mohapatra R, Li L, Mahalingam R, Tiedemann K, Campeau PM, Reinhardt DP, Fibronectin Isoforms Promote Postnatal Skeletal Development. Matrix Biol. 2024 Aug 17; |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
2* | J:85546 Gill SE, Pape MC, Khokha R, Watson AJ, Leco KJ, A null mutation for tissue inhibitor of metalloproteinases-3 (Timp-3) impairs murine bronchiole branching morphogenesis. Dev Biol. 2003 Sep 15;261(2):313-23 |
1 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:185218 Hall-Glenn F, De Young RA, Huang BL, van Handel B, Hofmann JJ, Chen TT, Choi A, Ong JR, Benya PD, Mikkola H, Iruela-Arispe ML, Lyons KM, CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PLoS One. 2012;7(2):e30562 |
2 | J:195895 Hanson KP, Jung JP, Tran QA, Hsu SP, Iida R, Ajeti V, Campagnola PJ, Eliceiri KW, Squirrell JM, Lyons GE, Ogle BM, Spatial and temporal analysis of extracellular matrix proteins in the developing murine heart: a blueprint for regeneration. Tissue Eng Part A. 2013 May;19(9-10):1132-43 |
1* | J:238590 Hayashi K, Ikari T, Sugiyama G, Sugiura T, Ohyama Y, Kumamaru W, Shirasuna K, Mori Y, Involvement of the T-box transcription factor Brachyury in early-stage embryonic mouse salivary gland. Biochem Biophys Res Commun. 2016 Sep 02;477(4):814-9 |
1 | J:146619 Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong TT, Shaw RM, Srivastava D, Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell. 2009 Feb;16(2):233-44 |
1 | J:306540 Jiang D, Correa-Gallegos D, Christ S, Stefanska A, Liu J, Ramesh P, Rajendran V, De Santis MM, Wagner DE, Rinkevich Y, Two succeeding fibroblastic lineages drive dermal development and the transition from regeneration to scarring. Nat Cell Biol. 2018 Apr;20(4):422-431 |
1 | J:173588 Kanazawa T, Ichii O, Otsuka S, Namiki Y, Hashimoto Y, Kon Y, Hepatocyte nuclear factor 4 alpha is associated with mesenchymal-epithelial transition in developing kidneys of C57BL/6 mice. J Vet Med Sci. 2011 May;73(5):601-7 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1* | J:20745 Naruse I, Fukui Y, Keino H, Taniguchi M, The arrest of luteinizing hormone-releasing hormone neuronal migration in the genetic arhinencephalic mouse embryo (Pdn/Pdn). Brain Res Dev Brain Res. 1994 Sep 16;81(2):178-84 |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
1* | J:36691 Peters JH, Hynes RO, Fibronectin isoform distribution in the mouse. I. The alternatively spliced EIIIB, EIIIA, and V segments show widespread codistribution in the developing mouse embryo. Cell Adhes Commun. 1996 Aug;4(2):103-25 |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
1 | J:188834 Shen D, Li J, Lepore JJ, Anderson TJ, Sinha S, Lin AY, Cheng L, Cohen ED, Roberts JD Jr, Dedhar S, Parmacek MS, Gerszten RE, Aortic aneurysm generation in mice with targeted deletion of integrin-linked kinase in vascular smooth muscle cells. Circ Res. 2011 Sep 2;109(6):616-28 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
1* | J:115860 Tada T, Widayati DT, Fukuta K, Morphological study of the transition of haematopoietic sites in the developing mouse during the peri-natal period. Anat Histol Embryol. 2006 Aug;35(4):235-40 |
1 | J:85775 Wagner TE, Frevert CW, Herzog EL, Schnapp LM, Expression of the integrin subunit alpha8 in murine lung development. J Histochem Cytochem. 2003 Oct;51(10):1307-15 |
1* | J:321805 Wang L, Sun M, Zhang Q, Dang S, Zhang W, ADAMTS18 regulates early branching morphogenesis of lacrimal gland and has a significant association with the risk of dry eye in mice. Exp Eye Res. 2022 Feb 28;218:109020 |
1 | J:361964 Wang M, Liu H, Zhang M, Niu X, Sun M, Wang F, Ni Y, Hong T, Zhang W, Dang S, The secreted protease ADAMTS18 links early isoform transformation and maturation of glomerular basement membrane macromolecules to the integrity of the glomerular filtration barrier. Biochem Biophys Res Commun. 2025 Mar 1;750:151386 |
1 | J:297072 Wurmser M, Chaverot N, Madani R, Sakai H, Negroni E, Demignon J, Saint-Pierre B, Mouly V, Amthor H, Tapscott S, Birchmeier C, Tajbakhsh S, Le Grand F, Sotiropoulos A, Maire P, SIX1 and SIX4 homeoproteins regulate PAX7+ progenitor cell properties during fetal epaxial myogenesis. Development. 2020 Oct 9;147(19):dev185975 |
1* | J:146829 Yamada W, Nagao K, Horikoshi K, Fujikura A, Ikeda E, Inagaki Y, Kakitani M, Tomizuka K, Miyazaki H, Suda T, Takubo K, Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun. 2009 Apr 10;381(3):453-8 |
1 | J:241335 Yang Y, Enis D, Zheng H, Chia S, Yang J, Chen M, Dhillon V, Papayannapoulou T, Kahn ML, Cell Adhesion Mediated by VCAM-ITGalpha9 Interactions Enables Lymphatic Development. Arterioscler Thromb Vasc Biol. 2015 May;35(5):1179-89 |
1 | J:296772 Yin W, Kim HT, Wang S, Gunawan F, Li R, Buettner C, Grohmann B, Sengle G, Sinner D, Offermanns S, Stainier DYR, Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis. Eur Respir J. 2019 Mar;53(3) |
1 | J:358835 Zhang J, Gao J, Zeng X, Wang Z, Chen C, Rong C, Li S, Cai L, Wang L, Zhang L, Tian Z, A novel Cdc42-YAP-fibronectin signaling axis regulates ameloblast differentiation during early enamel formation. Biochim Biophys Acta Mol Basis Dis. 2024 Nov 14;1871(2):167570 |
Fndc1 fibronectin type III domain containing 1 (Synonyms: 1110027O12Rik) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Fndc3b fibronectin type III domain containing 3B (Synonyms: 1600019O04Rik, fad104) | |
Results | Reference |
1 | J:178426 Kishimoto K, Nishizuka M, Ueda T, Kajita K, Ugawa S, Shimada S, Osada S, Imagawa M, Indispensable role of factor for adipocyte differentiation 104 (fad104) in lung maturation. Exp Cell Res. 2011 Sep 10;317(15):2110-23 |
Fndc3c1 fibronectin type III domain containing 3C1 (Synonyms: LOC333564) | |
Results | Reference |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
Fndc5 fibronectin type III domain containing 5 (Synonyms: 1500001L03Rik, PeP, Pxp) | |
Results | Reference |
1* | J:312359 Li X, Zhu X, Wu H, Van Dyke TE, Xu X, Morgan EF, Fu W, Liu C, Tu Q, Huang D, Chen J, Roles and Mechanisms of Irisin in Attenuating Pathological Features of Osteoarthritis. Front Cell Dev Biol. 2021;9:703670 |
Folr1 folate receptor alpha (Synonyms: FBP1, folate-binding protein 1, folate receptor [a], Folbp-1, Folbp1) | |
Results | Reference |
2 | J:214694 Kur E, Mecklenburg N, Cabrera RM, Willnow TE, Hammes A, LRP2 mediates folate uptake in the developing neural tube. J Cell Sci. 2014 May 15;127(Pt 10):2261-8 |
Fos FBJ osteosarcoma oncogene (Synonyms: c-fos, cFos, D12Rfj1) | |
Results | Reference |
1 | J:219809 Afelik S, Pool B, Schmerr M, Penton C, Jensen J, Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development. Dev Biol. 2015 Mar 15;399(2):204-17 |
1 | J:71816 Ayadi A, Zheng H, Sobieszczuk P, Buchwalter G, Moerman P, Alitalo K, Wasylyk B, Net-targeted mutant mice develop a vascular phenotype and up-regulate egr-1. EMBO J. 2001 Sep 17;20(18):5139-52 |
1* | J:23980 Carrasco D, Bravo R, Tissue-specific expression of the fos-related transcription factor fra-2 during mouse development. Oncogene. 1995 Mar 16;10(6):1069-79 |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
1 | J:7235 Muller R, Verma IM, Adamson ED, Expression of c-onc genes: c-fos transcripts accumulate to high levels during development of mouse placenta, yolk sac and amnion. EMBO J. 1983;2(5):679-84 |
1 | J:93107 Shirai K, Saika S, Okada Y, Senba E, Ohnishi Y, Expression of c-Fos and c-Jun in developing mouse lens. Ophthalmic Res. 2004 Jul-Aug;36(4):226-30 |
1 | J:214381 Spiegel I, Mardinly AR, Gabel HW, Bazinet JE, Couch CH, Tzeng CP, Harmin DA, Greenberg ME, Npas4 regulates excitatory-inhibitory balance within neural circuits through cell-type-specific gene programs. Cell. 2014 May 22;157(5):1216-29 |
1 | J:48539 Sunters A, McCluskey J, Grigoriadis AE, Control of cell cycle gene expression in bone development and during c-Fos-induced osteosarcoma formation. Dev Genet. 1998;22(4):386-97 |
Fosl1 fos-like antigen 1 (Synonyms: fra-1, Fra1) | |
Results | Reference |
1* | J:23980 Carrasco D, Bravo R, Tissue-specific expression of the fos-related transcription factor fra-2 during mouse development. Oncogene. 1995 Mar 16;10(6):1069-79 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:65292 Schreiber M, Wang Z, Jochum W, Fetka I, Elliott C, Wagner EF, Placental vascularisation requires the AP-1 component fra1. Development. 2000 Nov;127(22):4937-48 |
Fosl2 fos-like antigen 2 (Synonyms: Fra-2) | |
Results | Reference |
3* | J:23980 Carrasco D, Bravo R, Tissue-specific expression of the fos-related transcription factor fra-2 during mouse development. Oncogene. 1995 Mar 16;10(6):1069-79 |
Foxa1 forkhead box A1 (Synonyms: Hnf-3a, Hnf3a, Tcf-3a, Tcf3a) | |
Results | Reference |
1* | J:16244 Ang SL, Wierda A, Wong D, Stevens KA, Cascio S, Rossant J, Zaret KS, The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins. Development. 1993 Dec;119(4):1301-15 |
1 | J:176604 Bell SM, Zhang L, Mendell A, Xu Y, Haitchi HM, Lessard JL, Whitsett JA, Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. Dev Biol. 2011 Oct 1;358(1):79-90 |
2 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:309359 Brinkmeier ML, Bando H, Camarano AC, Fujio S, Yoshimoto K, de Souza FS, Camper SA, Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. J Clin Invest. 2020 Aug 3;130(8):4501-4515 |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1 | J:143476 Gao N, Lelay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH, Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development. Genes Dev. 2008 Dec 15;22(24):3435-48 |
1 | J:316093 Golden EJ, Larson ED, Shechtman LA, Trahan GD, Gaillard D, Fellin TJ, Scott JK, Jones KL, Barlow LA, Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function. Elife. 2021 May 19;10:e64013 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1 | J:199291 Jiang M, Ku WY, Fu J, Offermanns S, Hsu W, Que J, Gpr177 regulates pulmonary vasculature development. Development. 2013 Sep;140(17):3589-94 |
1* | J:17631 Kaestner KH, Hiemisch H, Luckow B, Schutz G, The HNF-3 gene family of transcription factors in mice: gene structure, cDNA sequence, and mRNA distribution. Genomics. 1994 Apr;20(3):377-85 |
1* | J:306453 Kajioka D, Suzuki K, Matsushita S, Hino S, Sato T, Takada S, Isono K, Takeo T, Kajimoto M, Nakagata N, Nakao M, Suyama M, DeFalco T, Miyagawa S, Yamada G, Sexual fate of murine external genitalia development: Conserved transcriptional competency for male-biased genes in both sexes. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2024067118 |
1 | J:147576 Kunisada M, Cui CY, Piao Y, Ko MS, Schlessinger D, Requirement for Shh and Fox family genes at different stages in sweat gland development. Hum Mol Genet. 2009 May 15;18(10):1769-78 |
1 | J:308430 Lopez-Gonzalez L, Alonso A, Garcia-Calero E, de Puelles E, Puelles L, Tangential Intrahypothalamic Migration of the Mouse Ventral Premamillary Nucleus and Fgf8 Signaling. Front Cell Dev Biol. 2021;9:676121 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Foxa2 forkhead box A2 (Synonyms: Hnf-3b, Hnf3b, HNF3-beta, HNF3beta, Tcf-3b, Tcf3b) | |
Results | Reference |
1 | J:359451 Amato CM, Xu X, Yao HH, An extragenital cell population contributes to urethra closure during mouse penis development. Sci Adv. 2024 Dec 6;10(49):eadp0673 |
1* | J:16244 Ang SL, Wierda A, Wong D, Stevens KA, Cascio S, Rossant J, Zaret KS, The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins. Development. 1993 Dec;119(4):1301-15 |
1 | J:180979 Besnard V, Wert SE, Ikegami M, Xu Y, Heffner C, Murray SA, Donahue LR, Whitsett JA, Maternal synchronization of gestational length and lung maturation. PLoS One. 2011;6(11):e26682 |
2* | J:104973 Besnard V, Wert SE, Kaestner KH, Whitsett JA, Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1. Am J Physiol Lung Cell Mol Physiol. 2005 Nov;289(5):L750-9 |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:282102 Canizares MA, Albors AR, Singer G, Suttie N, Gorkic M, Felts P, Storey KG, Multiple steps characterise ventricular layer attrition to form the ependymal cell lining of the adult mouse spinal cord central canal. J Anat. 2019 Oct 31; |
1 | J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82 |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1 | J:143476 Gao N, Lelay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH, Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development. Genes Dev. 2008 Dec 15;22(24):3435-48 |
1 | J:316093 Golden EJ, Larson ED, Shechtman LA, Trahan GD, Gaillard D, Fellin TJ, Scott JK, Jones KL, Barlow LA, Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function. Elife. 2021 May 19;10:e64013 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1* | J:212084 Herriges MJ, Swarr DT, Morley MP, Rathi KS, Peng T, Stewart KM, Morrisey EE, Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development. Genes Dev. 2014 Jun 15;28(12):1363-79 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1 | J:199291 Jiang M, Ku WY, Fu J, Offermanns S, Hsu W, Que J, Gpr177 regulates pulmonary vasculature development. Development. 2013 Sep;140(17):3589-94 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1* | J:17631 Kaestner KH, Hiemisch H, Luckow B, Schutz G, The HNF-3 gene family of transcription factors in mice: gene structure, cDNA sequence, and mRNA distribution. Genomics. 1994 Apr;20(3):377-85 |
1 | J:111670 Kyrmizi I, Hatzis P, Katrakili N, Tronche F, Gonzalez FJ, Talianidis I, Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev. 2006 Aug 15;20(16):2293-305 |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
1 | J:219800 Lungova V, Verheyden JM, Herriges J, Sun X, Thibeault SL, Ontogeny of the mouse vocal fold epithelium. Dev Biol. 2015 Mar 15;399(2):263-82 |
1 | J:121421 Shu W, Lu MM, Zhang Y, Tucker PW, Zhou D, Morrisey EE, Foxp2 and Foxp1 cooperatively regulate lung and esophagus development. Development. 2007 May;134(10):1991-2000 |
1* | J:332497 Tang X, Wei W, Snowball JM, Nakayasu ES, Bell SM, Ansong C, Lin X, Whitsett JA, EMC3 regulates mesenchymal cell survival via control of the mitotic spindle assembly. iScience. 2023 Jan 20;26(1):105667 |
1 | J:215769 Wang DH, Tiwari A, Kim ME, Clemons NJ, Regmi NL, Hodges WA, Berman DM, Montgomery EA, Watkins DN, Zhang X, Zhang Q, Jie C, Spechler SJ, Souza RF, Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia. J Clin Invest. 2014 Sep 2;124(9):3767-80 |
1* | J:201764 Yamamoto K, Matsuoka TA, Kawashima S, Takebe S, Kubo N, Miyatsuka T, Kaneto H, Shimomura I, A novel function of Onecut1 protein as a negative regulator of MafA gene expression. J Biol Chem. 2013 Jul 26;288(30):21648-58 |
1* | J:165724 Yu S, Poe B, Schwarz M, Elliot SA, Albertine KH, Fenton S, Garg V, Moon AM, Fetal and postnatal lung defects reveal a novel and required role for Fgf8 in lung development. Dev Biol. 2010 Nov 1;347(1):92-108 |
Foxa3 forkhead box A3 (Synonyms: Hnf-3g, Hnf3g, Tcf-3g, Tcf3g) | |
Results | Reference |
1 | J:181435 Gupta D, Harvey SA, Kaminski N, Swamynathan SK, Mouse conjunctival forniceal gene expression during postnatal development and its regulation by Kruppel-like factor 4. Invest Ophthalmol Vis Sci. 2011 Jul;52(8):4951-62 |
1* | J:17631 Kaestner KH, Hiemisch H, Luckow B, Schutz G, The HNF-3 gene family of transcription factors in mice: gene structure, cDNA sequence, and mRNA distribution. Genomics. 1994 Apr;20(3):377-85 |
Foxb1 forkhead box B1 (Synonyms: C43, Fkh5, Foxb1a, Foxb1b, Hfh-e5.1, Mf3, TWH) | |
Results | Reference |
1 | J:53741 Alvarez-Bolado G, Cecconi F, Wehr R, Gruss P, The fork head transcription factor Fkh5/Mf3 is a developmental marker gene for superior colliculus layers and derivatives of the hindbrain somatic afferent zone. Brain Res Dev Brain Res. 1999 Feb 5;112(2):205-15 |
1* | J:16244 Ang SL, Wierda A, Wong D, Stevens KA, Cascio S, Rossant J, Zaret KS, The formation and maintenance of the definitive endoderm lineage in the mouse: involvement of HNF3/forkhead proteins. Development. 1993 Dec;119(4):1301-15 |
1* | J:14165 Kaestner KH, Lee KH, Schlondorff J, Hiemisch H, Monaghan AP, Schutz G, Six members of the mouse forkhead gene family are developmentally regulated. Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7628-31 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
2 | J:172723 Szabo NE, Zhao T, Cankaya M, Stoykova A, Zhou X, Alvarez-Bolado G, Interaction between Axons and Specific Populations of Surrounding Cells Is Indispensable for Collateral Formation in the Mammillary System. PLoS One. 2011;6(5):e20315 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Foxb2 forkhead box B2 (Synonyms: Fkh4) | |
Results | Reference |
1* | J:14165 Kaestner KH, Lee KH, Schlondorff J, Hiemisch H, Monaghan AP, Schutz G, Six members of the mouse forkhead gene family are developmentally regulated. Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7628-31 |
Foxc1 forkhead box C1 (Synonyms: fkh-1, fkh1, Fkh1, FREAC3, frkhda, Mf1, Mf4) | |
Results | Reference |
2 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
1 | J:273024 DiNuoscio G, Atit RP, Wnt/beta-catenin signaling in the mouse embryonic cranial mesenchyme is required to sustain the emerging differentiated meningeal layers. Genesis. 2019 Jan;57(1):e23279 |
1* | J:86790 Gitler AD, Lu MM, Jiang YQ, Epstein JA, Gruber PJ, Molecular markers of cardiac endocardial cushion development. Dev Dyn. 2003 Dec;228(4):643-50 |
1 | J:134970 Inoue T, Ogawa M, Mikoshiba K, Aruga J, Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly. J Neurosci. 2008 Apr 30;28(18):4712-25 |
1* | J:14165 Kaestner KH, Lee KH, Schlondorff J, Hiemisch H, Monaghan AP, Schutz G, Six members of the mouse forkhead gene family are developmentally regulated. Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7628-31 |
1* | J:56425 Kidson SH, Kume T, Deng K, Winfrey V, Hogan BL, The forkhead/winged-helix gene, Mf1, is necessary for the normal development of the cornea and formation of the anterior chamber in the mouse eye. Dev Biol. 1999 Jul 15;211(2):306-22 |
1 | J:341276 Matrongolo MJ, Ho-Nguyen KT, Jain M, Ang PS, Reddy A, Schaper S, Tischfield MA, Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice. Development. 2023 Sep 15;150(18):dev201381 |
2 | J:107208 Mattiske D, Sommer P, Kidson SH, Hogan BL, The role of the forkhead transcription factor, Foxc1, in the development of the mouse lacrimal gland. Dev Dyn. 2006 Apr;235(4):1074-80 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Foxc2 forkhead box C2 (Synonyms: Fkh14, Hfhbf3, Mfh1, MFH-1) | |
Results | Reference |
2 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
1 | J:269938 Bovay E, Sabine A, Prat-Luri B, Kim S, Son K, Willrodt AH, Olsson C, Halin C, Kiefer F, Betsholtz C, Jeon NL, Luther SA, Petrova TV, Multiple roles of lymphatic vessels in peripheral lymph node development. J Exp Med. 2018 Nov 5;215(11):2760-2777 |
1 | J:233304 Cha B, Geng X, Mahamud MR, Fu J, Mukherjee A, Kim Y, Jho EH, Kim TH, Kahn ML, Xia L, Dixon JB, Chen H, Srinivasan RS, Mechanotransduction activates canonical Wnt/beta-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves. Genes Dev. 2016 Jun 15;30(12):1454-69 |
1 | J:301556 Cha B, Ho YC, Geng X, Mahamud MR, Chen L, Kim Y, Choi D, Kim TH, Randolph GJ, Cao X, Chen H, Srinivasan RS, YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling. Development. 2020 Dec 13;147(23):dev195453 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:93150 Dagenais SL, Hartsough RL, Erickson RP, Witte MH, Butler MG, Glover TW, Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome. Gene Expr Patterns. 2004 Oct;4(6):611-9 |
1 | J:228882 Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS, Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016 Jan 1;409(1):218-33 |
1* | J:86790 Gitler AD, Lu MM, Jiang YQ, Epstein JA, Gruber PJ, Molecular markers of cardiac endocardial cushion development. Dev Dyn. 2003 Dec;228(4):643-50 |
1 | J:341378 Iyer D, Mastrogiacomo DM, Li K, Banerjee R, Yang Y, Scallan JP, eNOS Regulates Lymphatic Valve Specification by Controlling beta-Catenin Signaling During Embryogenesis in Mice. Arterioscler Thromb Vasc Biol. 2023 Sep 28; |
1* | J:33548 Kaestner KH, Bleckmann SC, Monaghan AP, Schlondorff J, Mincheva A, Lichter P, Schutz G, Clustered arrangement of winged helix genes fkh-6 and MFH-1: possible implications for mesoderm development. Development. 1996 Jun;122(6):1751-8 |
2 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
1 | J:262023 Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K, Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling. Circ Res. 2017 Apr 14;120(8):1276-1288 |
1 | J:149138 Norrmen C, Ivanov KI, Cheng J, Zangger N, Delorenzi M, Jaquet M, Miura N, Puolakkainen P, Horsley V, Hu J, Augustin HG, Yla-Herttuala S, Alitalo K, Petrova TV, FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1. J Cell Biol. 2009 May 4;185(3):439-57 |
2 | J:256746 Wang X, Shan X, Gregory-Evans CY, A mouse model of aniridia reveals the in vivo downstream targets of Pax6 driving iris and ciliary body development in the eye. Biochim Biophys Acta. 2017 Jan;1863(1):60-67 |
1 | J:350084 Zhang L, Liu X, Li W, Liu K, Zhang J, Liu X, Wang J, Integrative transcriptomic profiling of ncRNAs and mRNAs in developing mouse lens. Front Genet. 2024;15:1405715 |
Foxd1 forkhead box D1 (Synonyms: BF-2, FREAC4, Hfh10, Hfhbf2) | |
Results | Reference |
1 | J:262819 Bohnenpoll T, Feraric S, Nattkemper M, Weiss AC, Rudat C, Meuser M, Trowe MO, Kispert A, Diversification of Cell Lineages in Ureter Development. J Am Soc Nephrol. 2017 Jun;28(6):1792-1801 |
1 | J:101176 Grieshammer U, Cebrian C, Ilagan R, Meyers E, Herzlinger D, Martin GR, FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons. Development. 2005 Sep;132(17):3847-57 |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
1 | J:33767 Hatini V, Huh SO, Herzlinger D, Soares VC, Lai E, Essential role of stromal mesenchyme in kidney morphogenesis revealed by targeted disruption of Winged Helix transcription factor BF-2. Genes Dev. 1996 Jun 15;10(12):1467-78 |
1* | J:20922 Hatini V, Tao W, Lai E, Expression of winged helix genes, BF-1 and BF-2, define adjacent domains within the developing forebrain and retina. J Neurobiol. 1994 Oct;25(10):1293-309 |
1 | J:94392 Herrera E, Marcus R, Li S, Williams SE, Erskine L, Lai E, Mason C, Foxd1 is required for proper formation of the optic chiasm. Development. 2004 Nov;131(22):5727-39 |
1 | J:95358 Levinson RS, Batourina E, Choi C, Vorontchikhina M, Kitajewski J, Mendelsohn CL, Foxd1-dependent signals control cellularity in the renal capsule, a structure required for normal renal development. Development. 2005 Feb;132(3):529-39 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
1 | J:185279 Paces-Fessy M, Fabre M, Lesaulnier C, Cereghini S, Hnf1b and Pax2 cooperate to control different pathways in kidney and ureter morphogenesis. Hum Mol Genet. 2012 Jul 15;21(14):3143-55 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:142507 Tian NM, Pratt T, Price DJ, Foxg1 regulates retinal axon pathfinding by repressing an ipsilateral program in nasal retina and by causing optic chiasm cells to exert a net axonal growth-promoting activity. Development. 2008 Dec;135(24):4081-9 |
Foxd3 forkhead box D3 (Synonyms: CWH3, Genesis, Hfh2) | |
Results | Reference |
2 | J:182762 Mundell NA, Plank JL, LeGrone AW, Frist AY, Zhu L, Shin MK, Southard-Smith EM, Labosky PA, Enteric nervous system specific deletion of Foxd3 disrupts glial cell differentiation and activates compensatory enteric progenitors. Dev Biol. 2012 Mar 15;363(2):373-87 |
1 | J:178995 Stam FJ, Hendricks TJ, Zhang J, Geiman EJ, Francius C, Labosky PA, Clotman F, Goulding M, Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program. Development. 2012 Jan;139(1):179-90 |
Foxd4 forkhead box D4 (Synonyms: Fkh2, FREAC5) | |
Results | Reference |
1* | J:14165 Kaestner KH, Lee KH, Schlondorff J, Hiemisch H, Monaghan AP, Schutz G, Six members of the mouse forkhead gene family are developmentally regulated. Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7628-31 |
1* | J:30127 Kaestner KH, Monaghan AP, Kern H, Ang SL, Weitz S, Lichter P, Schutz G, The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization. J Biol Chem. 1995 Dec 15;270(50):30029-35 |
Foxe1 forkhead box E1 (Synonyms: thyroid transcription factor 2, Titf2) | |
Results | Reference |
1 | J:326201 Hayashi T, Eto K, Kadoya Y, Downregulation of ten-eleven translocation-2 triggers epithelial differentiation during organogenesis. Differentiation. 2022 May-Jun;125:45-53 |
Foxe3 forkhead box E3 (Synonyms: FREAC8, rct) | |
Results | Reference |
1* | J:63706 Brownell I, Dirksen M, Jamrich M, Forkhead Foxe3 maps to the dysgenetic lens locus and is critical in lens development and differentiation. Genesis. 2000 Jun;27(2):81-93 |
1 | J:223109 Choi JJ, Ting CT, Trogrlic L, Milevski SV, Familari M, Martinez G, de Iongh RU, A role for smoothened during murine lens and cornea development. PLoS One. 2014;9(9):e108037 |
1* | J:225905 Dash S, Dang CA, Beebe DC, Lachke SA, Deficiency of the RNA binding protein caprin2 causes lens defects and features of peters anomaly. Dev Dyn. 2015 Oct;244(10):1313-27 |
1 | J:235665 He S, Limi S, McGreal RS, Xie Q, Brennan LA, Kantorow WL, Kokavec J, Majumdar R, Hou H Jr, Edelmann W, Liu W, Ashery-Padan R, Zavadil J, Kantorow M, Skoultchi AI, Stopka T, Cvekl A, Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation. Development. 2016 Jun 1;143(11):1937-47 |
1 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
2 | J:207861 Manthey AL, Lachke SA, FitzGerald PG, Mason RW, Scheiblin DA, McDonald JH, Duncan MK, Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development. Mech Dev. 2014 Feb;131:86-110 |
1 | J:131815 Pontoriero GF, Deschamps P, Ashery-Padan R, Wong R, Yang Y, Zavadil J, Cvekl A, Sullivan S, Williams T, West-Mays JA, Cell autonomous roles for AP-2alpha in lens vesicle separation and maintenance of the lens epithelial cell phenotype. Dev Dyn. 2008 Mar;237(3):602-17 |
1 | J:343554 Sun Q, Li J, Ma J, Zheng Y, Ju R, Li X, Ren X, Huang L, Chen R, Tan X, Luo L, JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development. Invest Ophthalmol Vis Sci. 2023 Dec 1;64(15):15 |
1 | J:342871 Xiang J, Pompetti AJ, Faranda AP, Wang Y, Novo SG, Li DW, Duncan MK, ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment. Cells. 2023 Nov 16;12(22) |
Foxf1 forkhead box F1 (Synonyms: Foxf1, Foxf1a, Freac-1, FREAC1, Hfh8, HFH-8) | |
Results | Reference |
1* | J:212084 Herriges MJ, Swarr DT, Morley MP, Rathi KS, Peng T, Stewart KM, Morrisey EE, Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development. Genes Dev. 2014 Jun 15;28(12):1363-79 |
1 | J:199291 Jiang M, Ku WY, Fu J, Offermanns S, Hsu W, Que J, Gpr177 regulates pulmonary vasculature development. Development. 2013 Sep;140(17):3589-94 |
1 | J:327415 Jing J, Feng J, Yuan Y, Guo T, Lei J, Pei F, Ho TV, Chai Y, Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022 Aug 16;13(1):4803 |
1* | J:45679 Peterson RS, Lim L, Ye H, Zhou H, Overdier DG, Costa RH, The winged helix transcriptional activator HFH-8 is expressed in the mesoderm of the primitive streak stage of mouse embryos and its cellular derivatives. Mech Dev. 1997 Dec;69(1-2):53-69 |
1 | J:266598 Ustiyan V, Bolte C, Zhang Y, Han L, Xu Y, Yutzey KE, Zorn AM, Kalin TV, Shannon JM, Kalinichenko VV, FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme. Dev Biol. 2018 Nov 1;443(1):50-63 |
Foxf2 forkhead box F2 (Synonyms: Fkh20, FREAC2, LUN) | |
Results | Reference |
1 | J:279187 Bolte C, Ren X, Tomley T, Ustiyan V, Pradhan A, Hoggatt A, Kalin TV, Herring BP, Kalinichenko VV, Forkhead box F2 regulation of platelet-derived growth factor and myocardin/serum response factor signaling is essential for intestinal development. J Biol Chem. 2015 Mar 20;290(12):7563-75 |
Foxg1 forkhead box G1 (Synonyms: 2900064B05Rik, Bf1, BF-1, Hfh9, Hfhbf1) | |
Results | Reference |
1 | J:341148 Bosze B, Suarez-Navarro J, Cajias I, Brzezinski Iv JA, Brown NL, Notch pathway mutants do not equivalently perturb mouse embryonic retinal development. PLoS Genet. 2023 Sep;19(9):e1010928 |
3 | J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5 |
1 | J:133461 Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH, Schier AF, Dulac C, Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 2008 Jan 10;57(1):41-55 |
2 | J:136319 Duggan CD, Demaria S, Baudhuin A, Stafford D, Ngai J, Foxg1 is required for development of the vertebrate olfactory system. J Neurosci. 2008 May 14;28(20):5229-39 |
1 | J:329946 Erickson KR, Farmer R, Merritt JK, Miletic Lanaghan Z, Does MD, Ramadass K, Landman BA, Cutting LE, Neul JL, Behavioral and brain anatomical analysis of Foxg1 heterozygous mice. PLoS One. 2022;17(10):e0266861 |
1* | J:320429 Falcone C, Santo M, Liuzzi G, Cannizzaro N, Grudina C, Valencic E, Peruzzotti-Jametti L, Pluchino S, Mallamaci A, Foxg1 Antagonizes Neocortical Stem Cell Progression to Astrogenesis. Cereb Cortex. 2019 Dec 17;29(12):4903-4918 |
1* | J:112208 Fotaki V, Yu T, Zaki PA, Mason JO, Price DJ, Abnormal positioning of diencephalic cell types in neocortical tissue in the dorsal telencephalon of mice lacking functional Gli3. J Neurosci. 2006 Sep 6;26(36):9282-92 |
1 | J:314124 Gao Y, Duque-Wilckens N, Aljazi MB, Wu Y, Moeser AJ, Mias GI, Robison AJ, He J, Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors. Commun Biol. 2021 Jun 18;4(1):756 |
1 | J:119019 Gutin G, Fernandes M, Palazzolo L, Paek H, Yu K, Ornitz DM, McConnell SK, Hebert JM, FGF signalling generates ventral telencephalic cells independently of SHH. Development. 2006 Aug;133(15):2937-46 |
1* | J:20922 Hatini V, Tao W, Lai E, Expression of winged helix genes, BF-1 and BF-2, define adjacent domains within the developing forebrain and retina. J Neurobiol. 1994 Oct;25(10):1293-309 |
2* | J:62916 Hebert JM, McConnell SK, Targeting of cre to the Foxg1 (BF-1) locus mediates loxP recombination in the telencephalon and other developing head structures. Dev Biol. 2000 Jun 15;222(2):296-306 |
1 | J:325428 Liu J, Yang M, Su M, Liu B, Zhou K, Sun C, Ba R, Yu B, Zhang B, Zhang Z, Fan W, Wang K, Zhong M, Han J, Zhao C, FOXG1 sequentially orchestrates subtype specification of postmitotic cortical projection neurons. Sci Adv. 2022 May 27;8(21):eabh3568 |
1 | J:188355 Miyoshi G, Fishell G, Dynamic FoxG1 expression coordinates the integration of multipolar pyramidal neuron precursors into the cortical plate. Neuron. 2012 Jun 21;74(6):1045-58 |
1* | J:74240 Mui SH, Hindges R, O'Leary DD, Lemke G, Bertuzzi S, The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye. Development. 2002 Feb;129(3):797-804 |
1 | J:131109 Ohkubo Y, Uchida AO, Shin D, Partanen J, Vaccarino FM, Fibroblast growth factor receptor 1 is required for the proliferation of hippocampal progenitor cells and for hippocampal growth in mouse. J Neurosci. 2004 Jul 7;24(27):6057-69 |
4* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:154376 Stottmann RW, Tran PV, Turbe-Doan A, Beier DR, Ttc21b is required to restrict sonic hedgehog activity in the developing mouse forebrain. Dev Biol. 2009 Nov 1;335(1):166-78 |
3* | J:302089 Vezzali R, Weise SC, Hellbach N, Machado V, Heidrich S, Vogel T, The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons. Oncotarget. 2016 Jun 21;7(25):37436-37455 |
1* | J:180986 Wei Q, Condie BG, A focused in situ hybridization screen identifies candidate transcriptional regulators of thymic epithelial cell development and function. PLoS One. 2011;6(11):e26795 |
2 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Foxi1 forkhead box I1 (Synonyms: Fkh10, Hfh3, HFH-3) | |
Results | Reference |
1 | J:241013 Grassmeyer J, Mukherjee M, deRiso J, Hettinger C, Bailey M, Sinha S, Visvader JE, Zhao H, Fogarty E, Surendran K, Elf5 is a principal cell lineage specific transcription factor in the kidney that contributes to Aqp2 and Avpr2 gene expression. Dev Biol. 2017 Apr 01;424(1):77-89 |
1 | J:82307 Hulander M, Kiernan AE, Blomqvist SR, Carlsson P, Samuelsson EJ, Johansson BR, Steel KP, Enerback S, Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice. Development. 2003 May;130(9):2013-25 |
1 | J:223640 Vidarsson H, Westergren R, Heglind M, Blomqvist SR, Breton S, Enerback S, The forkhead transcription factor Foxi1 is a master regulator of vacuolar H-ATPase proton pump subunits in the inner ear, kidney and epididymis. PLoS One. 2009;4(2):e4471 |
Foxi2 forkhead box I2 (Synonyms: B130055A05Rik) | |
Results | Reference |
1* | J:104058 Wijchers PJ, Hoekman MF, Burbach JP, Smidt MP, Cloning and analysis of the murine Foxi2 transcription factor. Biochim Biophys Acta. 2005 Nov 10;1731(2):133-8 |
Foxi3 forkhead box I3 | |
Results | Reference |
1* | J:324129 Moreci RS, Lechler T, KIF18B is a cell type-specific regulator of spindle orientation in the epidermis. Mol Biol Cell. 2021 Nov 1;32(21):ar29 |
1 | J:238111 Shirokova V, Biggs LC, Jussila M, Ohyama T, Groves AK, Mikkola ML, Foxi3 Deficiency Compromises Hair Follicle Stem Cell Specification and Activation. Stem Cells. 2016 Jul;34(7):1896-908 |
Foxj1 forkhead box J1 (Synonyms: FKHL-13, Hfh4, HFH-4) | |
Results | Reference |
1* | J:253968 Abdelhamed Z, Vuong SM, Hill L, Shula C, Timms A, Beier D, Campbell K, Mangano FT, Stottmann RW, Goto J, A mutation in Ccdc39 causes neonatal hydrocephalus with abnormal motile cilia development in mice. Development. 2018 Jan 9;145(1):dev154500 |
1* | J:230806 Arbi M, Pefani DE, Kyrousi C, Lalioti ME, Kalogeropoulou A, Papanastasiou AD, Taraviras S, Lygerou Z, GemC1 controls multiciliogenesis in the airway epithelium. EMBO Rep. 2016 Mar;17(3):400-13 |
1* | J:171712 Bird AD, Flecknoe SJ, Tan KH, Olsson PF, Antony N, Mantamadiotis T, Hooper SB, Cole TJ, cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development. PLoS One. 2011;6(3):e17843 |
1 | J:309359 Brinkmeier ML, Bando H, Camarano AC, Fujio S, Yoshimoto K, de Souza FS, Camper SA, Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. J Clin Invest. 2020 Aug 3;130(8):4501-4515 |
2 | J:282102 Canizares MA, Albors AR, Singer G, Suttie N, Gorkic M, Felts P, Storey KG, Multiple steps characterise ventricular layer attrition to form the ependymal cell lining of the adult mouse spinal cord central canal. J Anat. 2019 Oct 31; |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
2* | J:25207 Hackett BP, Brody SL, Liang M, Zeitz ID, Bruns LA, Gitlin JD, Primary structure of hepatocyte nuclear factor/forkhead homologue 4 and characterization of gene expression in the developing respiratory and reproductive epithelium. Proc Natl Acad Sci U S A. 1995 May 9;92(10):4249-53 |
1* | J:306246 He M, Wu B, Ye W, Le DD, Sinclair AW, Padovano V, Chen Y, Li KX, Sit R, Tan M, Caplan MJ, Neff N, Jan YN, Darmanis S, Jan LY, Chloride channels regulate differentiation and barrier functions of the mammalian airway. Elife. 2020 Apr 14;9:e53085 |
1 | J:87186 Huang T, You Y, Spoor MS, Richer EJ, Kudva VV, Paige RC, Seiler MP, Liebler JM, Zabner J, Plopper CG, Brody SL, Foxj1 is required for apical localization of ezrin in airway epithelial cells. J Cell Sci. 2003 Dec 15;116(Pt 24):4935-45 |
1 | J:233686 Jia WJ, Jiang S, Tang QL, Shen D, Xue B, Ning W, Li CJ, Geranylgeranyl Diphosphate Synthase Modulates Fetal Lung Branching Morphogenesis Possibly through Controlling K-Ras Prenylation. Am J Pathol. 2016 Jun;186(6):1454-65 |
1 | J:308827 Kaiser K, Jang A, Kompanikova P, Lun MP, Prochazka J, Machon O, Dani N, Prochazkova M, Laurent B, Gyllborg D, van Amerongen R, Fame RM, Gupta S, Wu F, Barker RA, Bukova I, Sedlacek R, Kozmik Z, Arenas E, Lehtinen MK, Bryja V, MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus. Development. 2021 May 15;148(10):dev192054 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1* | J:310453 Kyrousi C, Arbi M, Pilz GA, Pefani DE, Lalioti ME, Ninkovic J, Gotz M, Lygerou Z, Taraviras S, Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche. Development. 2015 Nov 1;142(21):3661-74 |
1 | J:166685 Love D, Li FQ, Burke MC, Cyge B, Ohmitsu M, Cabello J, Larson JE, Brody SL, Cohen JC, Takemaru K, Altered lung morphogenesis, epithelial cell differentiation and mechanics in mice deficient in the Wnt/beta-catenin antagonist Chibby. PLoS One. 2010;5(10):e13600 |
1* | J:346057 Lu D, Zhi Y, Su H, Lin X, Lin J, Shi Y, Yi W, Hong C, Zhang T, Fu Z, Chen LY, Zhao Z, Li R, Xu Z, Chen W, Wang N, Xu D, ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells. Cell Rep. 2024 Feb 24;43(3):113818 |
1 | J:156690 Morimoto M, Liu Z, Cheng HT, Winters N, Bader D, Kopan R, Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate. J Cell Sci. 2010 Jan 15;123(Pt 2):213-24 |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
1* | J:105760 Swetloff A, Ferretti P, Changes in E2F5 intracellular localization in mouse and human choroid plexus epithelium with development. Int J Dev Biol. 2005;49(7):859-65 |
1 | J:55155 Tichelaar JW, Wert SE, Costa RH, Kimura S, Whitsett JA, HNF-3/forkhead homologue-4 (HFH-4) is expressed in ciliated epithelial cells in the developing mouse lung. J Histochem Cytochem. 1999 Jun;47(6):823-32 |
1* | J:141013 Venugopalan SR, Amen MA, Wang J, Wong L, Cavender AC, D'Souza RN, Akerlund M, Brody SL, Hjalt TA, Amendt BA, Novel expression and transcriptional regulation of FoxJ1 during oro-facial morphogenesis. Hum Mol Genet. 2008 Dec 1;17(23):3643-54 |
1 | J:312414 Yogosawa S, Ohkido M, Horii T, Okazaki Y, Nakayama J, Yoshida S, Toyokuni S, Hatada I, Morimoto M, Yoshida K, Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient. Commun Biol. 2021 Oct 20;4(1):1204 |
Foxk1 forkhead box K1 (Synonyms: A630048H08Rik, Mnf) | |
Results | Reference |
1* | J:42857 Yang Q, Bassel-Duby R, Williams RS, Transient expression of a winged-helix protein, MNF-beta, during myogenesis. Mol Cell Biol. 1997 Sep;17(9):5236-43 |
Foxk2 forkhead box K2 (Synonyms: 1110054H05Rik, 5730434B08Rik, Ilf1) | |
Results | Reference |
1 | J:105897 Wijchers PJ, Hoekman MF, Burbach JP, Smidt MP, Identification of forkhead transcription factors in cortical and dopaminergic areas of the adult murine brain. Brain Res. 2006 Jan 12;1068(1):23-33 |
Foxl1 forkhead box L1 (Synonyms: fkh-6, fkh6, Fkh6, FREAC7) | |
Results | Reference |
1* | J:33548 Kaestner KH, Bleckmann SC, Monaghan AP, Schlondorff J, Mincheva A, Lichter P, Schutz G, Clustered arrangement of winged helix genes fkh-6 and MFH-1: possible implications for mesoderm development. Development. 1996 Jun;122(6):1751-8 |
1* | J:14165 Kaestner KH, Lee KH, Schlondorff J, Hiemisch H, Monaghan AP, Schutz G, Six members of the mouse forkhead gene family are developmentally regulated. Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7628-31 |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
Foxl2 forkhead box L2 (Synonyms: Pfrk) | |
Results | Reference |
1 | J:359451 Amato CM, Xu X, Yao HH, An extragenital cell population contributes to urethra closure during mouse penis development. Sci Adv. 2024 Dec 6;10(49):eadp0673 |
1 | J:290897 Auguste A, Chassot AA, Gregoire EP, Renault L, Pannetier M, Treier M, Pailhoux E, Chaboissier MC, Loss of R-spondin1 and Foxl2 amplifies female-to-male sex reversal in XX mice. Sex Dev. 2011;5(6):304-17 |
1* | J:114716 Ellsworth BS, Egashira N, Haller JL, Butts DL, Cocquet J, Clay CM, Osamura RY, Camper SA, FOXL2 in the pituitary: molecular, genetic, and developmental analysis. Mol Endocrinol. 2006 Nov;20(11):2796-805 |
1 | J:152858 Garcia-Ortiz JE, Pelosi E, Omari S, Nedorezov T, Piao Y, Karmazin J, Uda M, Cao A, Cole SW, Forabosco A, Schlessinger D, Ottolenghi C, Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Dev Biol. 2009;9:36 |
1 | J:221983 Heude E, Bellessort B, Fontaine A, Hamazaki M, Treier AC, Treier M, Levi G, Narboux-Neme N, Etiology of craniofacial malformations in mouse models of blepharophimosis, ptosis and epicanthus inversus syndrome. Hum Mol Genet. 2015 Mar 15;24(6):1670-81 |
1* | J:168597 Kashimada K, Pelosi E, Chen H, Schlessinger D, Wilhelm D, Koopman P, FOXL2 and BMP2 act cooperatively to regulate follistatin gene expression during ovarian development. Endocrinology. 2011 Jan;152(1):272-80 |
1 | J:294981 Liu X, Castle V, Taketo T, Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development. Cell Death Dis. 2019 Oct 17;10(11):790 |
1 | J:84353 Loffler KA, Zarkower D, Koopman P, Etiology of ovarian failure in blepharophimosis ptosis epicanthus inversus syndrome: FOXL2 is a conserved, early-acting gene in vertebrate ovarian development. Endocrinology. 2003 Jul;144(7):3237-43 |
1* | J:173838 Manuylov NL, Zhou B, Ma Q, Fox SC, Pu WT, Tevosian SG, Conditional ablation of Gata4 and Fog2 genes in mice reveals their distinct roles in mammalian sexual differentiation. Dev Biol. 2011 May 15;353(2):229-41 |
1* | J:239654 Marongiu M, Marcia L, Pelosi E, Lovicu M, Deiana M, Zhang Y, Puddu A, Loi A, Uda M, Forabosco A, Schlessinger D, Crisponi L, FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice. BMC Dev Biol. 2015 Jul 02;15:27 |
1 | J:326550 Mayere C, Regard V, Perea-Gomez A, Bunce C, Neirijnck Y, Djari C, Bellido-Carreras N, Sararols P, Reeves R, Greenaway S, Simon M, Siggers P, Condrea D, Kuhne F, Gantar I, Tang F, Stevant I, Batti L, Ghyselinck NB, Wilhelm D, Greenfield A, Capel B, Chaboissier MC, Nef S, Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad. Sci Adv. 2022 May 27;8(21):eabm0972 |
1 | J:330583 McKey J, Anbarci DN, Bunce C, Ontiveros AE, Behringer RR, Capel B, Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii. Elife. 2022 Sep 27;11:e81088 |
1 | J:273473 McKey J, Bunce C, Batchvarov IS, Ornitz DM, Capel B, Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5570-5575 |
1 | J:361601 Park CJ, Oh JE, Lin P, Zhou S, Bunnell M, Bikorimana E, Spinella MJ, Lim HJ, Ko CJ, A Dynamic Shift in Estrogen Receptor Expression During Granulosa Cell Differentiation in the Ovary. Endocrinology. 2025 Jan 6;166(2) |
1 | J:197599 Pitetti JL, Calvel P, Romero Y, Conne B, Truong V, Papaioannou MD, Schaad O, Docquier M, Herrera PL, Wilhelm D, Nef S, Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice. PLoS Genet. 2013;9(1):e1003160 |
1* | J:326026 Prokopuk L, Jarred EG, Blucher RO, McLaughlin EA, Stringer JM, Western PS, An essential role for Polycomb Repressive Complex 2 in the mouse ovary. Reproduction. 2022 Feb 17;163(3):167-182 |
1 | J:216158 Rastetter RH, Bernard P, Palmer JS, Chassot AA, Chen H, Western PS, Ramsay RG, Chaboissier MC, Wilhelm D, Marker genes identify three somatic cell types in the fetal mouse ovary. Dev Biol. 2014 Oct 15;394(2):242-52 |
1* | J:180844 Strauss TJ, Castrillon DH, Hammes SR, GATA-like protein-1 (GLP-1) is required for normal germ cell development during embryonic oogenesis. Reproduction. 2011 Feb;141(2):173-81 |
1 | J:356085 Wang J, Tian GG, Zheng Z, Li B, Xing Q, Wu J, Comprehensive Transcriptomic Analysis of Mouse Gonadal Development Involving Sexual Differentiation, Meiosis and Gametogenesis. Biol Proced Online. 2019;21:20 |
Foxm1 forkhead box M1 (Synonyms: Fkh16, Foxm1b, HFH-11B, Mpm2, Trident, WIN) | |
Results | Reference |
1 | J:237816 Calderon MJ, Ploegman AG, Bailey B, Jung DO, Navratil AM, Ellsworth BS, Loss of Foxm1 Results in Reduced Somatotrope Cell Number during Mouse Embryogenesis. PLoS One. 2015;10(6):e0128942 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1 | J:206964 Wu X, Gu X, Han X, Du A, Jiang Y, Zhang X, Wang Y, Cao G, Zhao C, A novel function for Foxm1 in interkinetic nuclear migration in the developing telencephalon and anxiety-related behavior. J Neurosci. 2014 Jan 22;34(4):1510-22 |
Foxn1 forkhead box N1 (Synonyms: D11Bhm185e, Hfh11, whn) | |
Results | Reference |
1 | J:304609 Caprio C, Lania G, Bilio M, Ferrentino R, Chen L, Baldini A, EZH2 is required for parathyroid and thymic development through differentiation of the third pharyngeal pouch endoderm. Dis Model Mech. 2021 Feb 19;:dmm.046789 |
1 | J:309371 Chilukuri RV, Patel VK, Martinez M, Guyden JC, Samms MD, The Antigenic Determinant That Defines Thymic Nurse Cells Is Expressed by Thymic Epithelial Progenitor Cells. Front Cell Dev Biol. 2014 Apr 28;2(13) |
1* | J:58554 Dear TN, Boehm T, Diverse mRNA expression patterns of the mouse calpain genes Capn5, Capn6 and Capn11 during development. Mech Dev. 1999 Dec;89(1-2):201-9 |
1 | J:125817 Gordon J, Xiao S, Hughes B rd, Su DM, Navarre SP, Condie BG, Manley NR, Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus. BMC Dev Biol. 2007;7:69 |
1* | J:149208 Itoi M, Tsukamoto N, Amagai T, Expression of Dll4 and CCL25 in Foxn1-negative epithelial cells in the post-natal thymus. Int Immunol. 2007 Feb;19(2):127-32 |
1* | J:278361 Larsen BM, Cowan JE, Wang Y, Tanaka Y, Zhao Y, Voisin B, Constantinides MG, Nagao K, Belkaid Y, Awasthi P, Takahama Y, Bhandoola A, Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells. J Immunol. 2019 Aug 1;203(3):686-695 |
1* | J:301543 Li J, Lee YK, Fu W, Whalen AM, Estable MC, Raftery LA, White K, Weiner L, Brissette JL, Modeling by disruption and a selected-for partner for the nude locus. EMBO Rep. 2020 Dec 28;:e49804 |
1* | J:58632 Meier N, Dear TN, Boehm T, Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation. Mech Dev. 1999 Dec;89(1-2):215-21 |
1* | J:180986 Wei Q, Condie BG, A focused in situ hybridization screen identifies candidate transcriptional regulators of thymic epithelial cell development and function. PLoS One. 2011;6(11):e26795 |
2* | J:63747 Zuklys S, Balciunaite G, Agarwal A, Fasler-Kan E, Palmer E, Hollander GA, Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). J Immunol. 2000 Aug 15;165(4):1976-83 |
1 | J:146244 Zuklys S, Gill J, Keller MP, Hauri-Hohl M, Zhanybekova S, Balciunaite G, Na KJ, Jeker LT, Hafen K, Tsukamoto N, Amagai T, Taketo MM, Krenger W, Hollander GA, Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. J Immunol. 2009 Mar 1;182(5):2997-3007 |
Foxn4 forkhead box N4 | |
Results | Reference |
1 | J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489 |
1* | J:71345 Gouge A, Holt J, Hardy AP, Sowden JC, Smith HK, Foxn4 - a new member of the forkhead gene family is expressed in the retina. Mech Dev. 2001 Sep;107(1-2):203-6 |
1* | J:306246 He M, Wu B, Ye W, Le DD, Sinclair AW, Padovano V, Chen Y, Li KX, Sit R, Tan M, Caplan MJ, Neff N, Jan YN, Darmanis S, Jan LY, Chloride channels regulate differentiation and barrier functions of the mammalian airway. Elife. 2020 Apr 14;9:e53085 |
1* | J:171626 Li S, Xiang M, Foxn4 influences alveologenesis during lung development. Dev Dyn. 2011 Jun;240(6):1512-7 |
1 | J:354849 Wutikeli H, Yu Y, Zhang T, Cao J, Nawy S, Shen Y, Role of Elavl-like RNA-binding protein in retinal development and signal transduction. Biochim Biophys Acta Mol Basis Dis. 2024 Sep 20;1871(1):167518 |
Foxo1 forkhead box O1 (Synonyms: Afxh, FKHR, Fkhr1, Foxo1a) | |
Results | Reference |
2 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
1* | J:104161 Hoekman MF, Jacobs FM, Smidt MP, Burbach JP, Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain. Gene Expr Patterns. 2006 Jan;6(2):134-40 |
1 | J:240480 Kapali J, Kabat BE, Schmidt KL, Stallings CE, Tippy M, Jung DO, Edwards BS, Nantie LB, Raeztman LT, Navratil AM, Ellsworth BS, Foxo1 Is Required for Normal Somatotrope Differentiation. Endocrinology. 2016 Nov;157(11):4351-4363 |
1* | J:258304 Pui HP, Saga Y, NANOS2 acts as an intrinsic regulator of gonocytes-to-spermatogonia transition in the murine testes. Mech Dev. 2018 Feb;149:27-40 |
1 | J:308685 Scallan JP, Knauer LA, Hou H, Castorena-Gonzalez JA, Davis MJ, Yang Y, Foxo1 deletion promotes the growth of new lymphatic valves. J Clin Invest. 2021 Jul 15;131(14) |
1 | J:324529 Stallings CE, Kapali J, Evans BW, McGee SR, Ellsworth BS, FOXO Transcription Factors Are Required for Normal Somatotrope Function and Growth. Endocrinology. 2022 Feb 1;163(2) |
1 | J:208719 Tsai MJ, Yang-Yen HF, Chiang MK, Wang MJ, Wu SS, Chen SH, TCTP is essential for beta-cell proliferation and mass expansion during development and beta-cell adaptation in response to insulin resistance. Endocrinology. 2014 Feb;155(2):392-404 |
1* | J:171501 Villarejo-Balcells B, Guichard S, Rigby PW, Carvajal JJ, Expression pattern of the FoxO1 gene during mouse embryonic development. Gene Expr Patterns. 2011 Jun-Jul;11(5-6):299-308 |
1* | J:310487 Xiang C, Frietze KK, Bi Y, Li Y, Dal Pozzo V, Pal S, Alexander N, Baubet V, D'Acunto V, Mason CE, Davuluri RV, Dahmane N, RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons. Mol Cell Biol. 2021 Jun 23;41(7):e0052620 |
2 | J:219874 Zhou J, Li H, Li X, Zhang G, Niu Y, Yuan Z, Herrup K, Zhang YW, Bu G, Xu H, Zhang J, The roles of Cdk5-mediated subcellular localization of FOXO1 in neuronal death. J Neurosci. 2015 Feb 11;35(6):2624-35 |
Foxo3 forkhead box O3 (Synonyms: 1110048B16Rik, 2010203A17Rik, Fkhr2, FKHRL1, Foxo3a) | |
Results | Reference |
2 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
1* | J:104161 Hoekman MF, Jacobs FM, Smidt MP, Burbach JP, Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain. Gene Expr Patterns. 2006 Jan;6(2):134-40 |
1 | J:324529 Stallings CE, Kapali J, Evans BW, McGee SR, Ellsworth BS, FOXO Transcription Factors Are Required for Normal Somatotrope Function and Growth. Endocrinology. 2022 Feb 1;163(2) |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1* | J:299510 Wang JJ, Ge W, Zhai QY, Liu JC, Sun XW, Liu WX, Li L, Lei CZ, Dyce PW, De Felici M, Shen W, Single-cell transcriptome landscape of ovarian cells during primordial follicle assembly in mice. PLoS Biol. 2020 Dec;18(12):e3001025 |
1 | J:362758 Zhang L, Li Y, Hu Y, Chen M, Cen C, Chen M, Lin L, Zhou J, Wang M, Cui X, Tang F, Gao F, Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression. FASEB J. 2022 Feb;36(2):e22131 |
Foxo4 forkhead box O4 (Synonyms: afx, Afxh, Foxo4, Mllt7) | |
Results | Reference |
1 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
1 | J:324529 Stallings CE, Kapali J, Evans BW, McGee SR, Ellsworth BS, FOXO Transcription Factors Are Required for Normal Somatotrope Function and Growth. Endocrinology. 2022 Feb 1;163(2) |
Foxo6 forkhead box O6 | |
Results | Reference |
1* | J:104161 Hoekman MF, Jacobs FM, Smidt MP, Burbach JP, Spatial and temporal expression of FoxO transcription factors in the developing and adult murine brain. Gene Expr Patterns. 2006 Jan;6(2):134-40 |
1 | J:238795 Paap RH, Oosterbroek S, Wagemans CM, von Oerthel L, Schellevis RD, Vastenhouw-van der Linden AJ, Groot Koerkamp MJ, Hoekman MF, Smidt MP, FoxO6 affects Plxna4-mediated neuronal migration during mouse cortical development. Proc Natl Acad Sci U S A. 2016 Oct 24; |
1 | J:324529 Stallings CE, Kapali J, Evans BW, McGee SR, Ellsworth BS, FOXO Transcription Factors Are Required for Normal Somatotrope Function and Growth. Endocrinology. 2022 Feb 1;163(2) |
Foxp1 forkhead box P1 (Synonyms: 3110052D19Rik, 4932443N09Rik) | |
Results | Reference |
1 | J:237201 Espinosa-Medina I, Saha O, Boismoreau F, Chettouh Z, Rossi F, Richardson WD, Brunet JF, The sacral autonomic outflow is sympathetic. Science. 2016 Nov 18;354(6314):893-897 |
2* | J:83154 Ferland RJ, Cherry TJ, Preware PO, Morrisey EE, Walsh CA, Characterization of Foxp2 and Foxp1 mRNA and protein in the developing and mature brain. J Comp Neurol. 2003 May 26;460(2):266-79 |
1* | J:125023 French CA, Groszer M, Preece C, Coupe AM, Rajewsky K, Fisher SE, Generation of mice with a conditional Foxp2 null allele. Genesis. 2007 Jul;45(7):440-6 |
1* | J:237748 Li X, Xiao J, Frohlich H, Tu X, Li L, Xu Y, Cao H, Qu J, Rappold GA, Chen JG, Foxp1 regulates cortical radial migration and neuronal morphogenesis in developing cerebral cortex. PLoS One. 2015;10(5):e0127671 |
1* | J:82200 Lu MM, Li S, Yang H, Morrisey EE, Foxp4: a novel member of the Foxp subfamily of winged-helix genes co-expressed with Foxp1 and Foxp2 in pulmonary and gut tissues. Mech Dev. 2002 Dec;119 Suppl 1:S197-202 |
1 | J:226687 Morello F, Prasad AA, Rehberg K, Vieira de Sa R, Anton-Bolanos N, Leyva-Diaz E, Adolfs Y, Tissir F, Lopez-Bendito G, Pasterkamp RJ, Frizzled3 Controls Axonal Polarity and Intermediate Target Entry during Striatal Pathway Development. J Neurosci. 2015 Oct 21;35(42):14205-19 |
1 | J:363605 Ortiz A, Ayhan F, Khandelwal N, Outland E, Jankovic M, Harper M, Konopka G, Cell-type-specific roles of FOXP1 in the excitatory neuronal lineage during early neocortical murine development. Cell Rep. 2025 Mar 5;44(3):115384 |
2 | J:287008 Pearson CA, Moore DM, Tucker HO, Dekker JD, Hu H, Miquelajauregui A, Novitch BG, Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates. Cell Rep. 2020 Feb 11;30(6):1964-1981.e3 |
1* | J:227089 Pirson M, Knoops B, Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617 |
2 | J:236735 Precious SV, Kelly CM, Reddington AE, Vinh NN, Stickland RC, Pekarik V, Scherf C, Jeyasingham R, Glasbey J, Holeiter M, Jones L, Taylor MV, Rosser AE, FoxP1 marks medium spiny neurons from precursors to maturity and is required for their differentiation. Exp Neurol. 2016 Aug;282:9-18 |
1 | J:246732 Saller MM, Huettl RE, Hanuschick P, Amend AL, Alberton P, Aszodi A, Huber AB, The role of Sema3-Npn-1 signaling during diaphragm innervation and muscle development. J Cell Sci. 2016 Sep 01;129(17):3295-308 |
1* | J:70542 Shu W, Yang H, Zhang L, Lu MM, Morrisey EE, Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors. J Biol Chem. 2001 Jul 20;276(29):27488-97 |
1 | J:350099 Song X, Chen H, Shang Z, Du H, Li Z, Wen Y, Liu G, Qi D, You Y, Yang Z, Zhang Z, Xu Z, Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons. Neurosci Bull. 2021 Jul;37(7):985-998 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
2 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
1 | J:264125 Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z, SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. Development. 2018 Jul 23;145(14):dev165456 |
1 | J:334713 Zhang J, Roberts JM, Chang F, Schwakopf J, Vetter ML, Jarid2 promotes temporal progression of retinal progenitors via repression of Foxp1. Cell Rep. 2023 Mar 28;42(3):112237 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
1 | J:218833 Zhao H, Zhou W, Yao Z, Wan Y, Cao J, Zhang L, Zhao J, Li H, Zhou R, Li B, Wei G, Zhang Z, French CA, Dekker JD, Yang Y, Fisher SE, Tucker HO, Guo X, Foxp1/2/4 regulate endochondral ossification as a suppresser complex. Dev Biol. 2015 Feb 15;398(2):242-54 |
Foxp2 forkhead box P2 (Synonyms: 2810043D05Rik, D0Kist7) | |
Results | Reference |
1 | J:350469 Alderman PJ, Saxon D, Torrijos-Saiz LI, Sharief M, Page CE, Baroudi JK, Biagiotti SW, Butyrkin VA, Melamed A, Kuo CT, Vicini S, Garcia-Verdugo JM, Herranz-Perez V, Corbin JG, Sorrells SF, Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala. Neuron. 2024 Feb 21;112(4):574-592.e10 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1* | J:345409 Cook AG, Bishop TV, Crowe HR, Stevens DN, Reine L, Joyner AL, Lawton AK, Cell division angle predicts the level of tissue mechanics that tune the amount of cerebellar folding. Development. 2024 Feb 1;151(3):dev202184 |
1 | J:304642 Dupacova N, Antosova B, Paces J, Kozmik Z, Meis homeobox genes control progenitor competence in the retina. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2013136118 |
1 | J:144651 Farkas LM, Haffner C, Giger T, Khaitovich P, Nowick K, Birchmeier C, Paabo S, Huttner WB, Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex. Neuron. 2008 Oct 9;60(1):40-55 |
1 | J:211816 Fei JF, Haffner C, Huttner WB, 3' UTR-dependent, miR-92-mediated restriction of Tis21 expression maintains asymmetric neural stem cell division to ensure proper neocortex size. Cell Rep. 2014 Apr 24;7(2):398-411 |
2* | J:83154 Ferland RJ, Cherry TJ, Preware PO, Morrisey EE, Walsh CA, Characterization of Foxp2 and Foxp1 mRNA and protein in the developing and mature brain. J Comp Neurol. 2003 May 26;460(2):266-79 |
2* | J:125023 French CA, Groszer M, Preece C, Coupe AM, Rajewsky K, Fisher SE, Generation of mice with a conditional Foxp2 null allele. Genesis. 2007 Jul;45(7):440-6 |
1* | J:278498 Friocourt F, Kozulin P, Belle M, Suarez R, Di-Poi N, Richards LJ, Giacobini P, Chedotal A, Shared and differential features of Robo3 expression pattern in amniotes. J Comp Neurol. 2019 Aug 15;527(12):2009-2029 |
1* | J:180013 Fujita H, Sugihara I, FoxP2 expression in the cerebellum and inferior olive: Development of the transverse stripe-shaped expression pattern in the mouse cerebellar cortex. J Comp Neurol. 2012 Feb 15;520(3):656-77 |
1 | J:233661 Garcia-Calero E, Botella-Lopez A, Bahamonde O, Perez-Balaguer A, Martinez S, FoxP2 protein levels regulate cell morphology changes and migration patterns in the vertebrate developing telencephalon. Brain Struct Funct. 2016 Jul;221(6):2905-17 |
1 | J:308528 Hernandez Vasquez MN, Ulvmar MH, Gonzalez-Loyola A, Kritikos I, Sun Y, He L, Halin C, Petrova TV, Makinen T, Transcription factor FOXP2 is a flow-induced regulator of collecting lymphatic vessels. EMBO J. 2021 Jun 15;40(12):e107192 |
1 | J:277609 Kast RJ, Lanjewar AL, Smith CD, Levitt P, FOXP2 exhibits projection neuron class specific expression, but is not required for multiple aspects of cortical histogenesis. Elife. 2019 May 17;8:e42012 |
1 | J:84725 Lai CS, Gerrelli D, Monaco AP, Fisher SE, Copp AJ, FOXP2 expression during brain development coincides with adult sites of pathology in a severe speech and language disorder. Brain. 2003 Nov;126(Pt 11):2455-62 |
1* | J:82200 Lu MM, Li S, Yang H, Morrisey EE, Foxp4: a novel member of the Foxp subfamily of winged-helix genes co-expressed with Foxp1 and Foxp2 in pulmonary and gut tissues. Mech Dev. 2002 Dec;119 Suppl 1:S197-202 |
1 | J:348685 Masuda A, Nishida K, Ajima R, Saga Y, Bakhtan M, Klar A, Hirata T, Zhu Y, A global gene regulatory program and its region-specific regulator partition neurons into commissural and ipsilateral projection types. Sci Adv. 2024 May 24;10(21):eadk2149 |
1 | J:191793 Schnatwinkel C, Niswander L, Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice. PLoS One. 2012;7(9):e44871 |
1 | J:287023 Schnerwitzki D, Perry S, Ivanova A, Caixeta FV, Cramer P, Gunther S, Weber K, Tafreshiha A, Becker L, Vargas Panesso IL, Klopstock T, Hrabe de Angelis M, Schmidt M, Kullander K, Englert C, Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord. Life Sci Alliance. 2018 Aug;1(4):e201800106 |
1* | J:70542 Shu W, Yang H, Zhang L, Lu MM, Morrisey EE, Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors. J Biol Chem. 2001 Jul 20;276(29):27488-97 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1* | J:287411 Tran HN, Park W, Seong S, Jeong JE, Nguyen QH, Yoon J, Baek K, Jeong Y, Tcf7l2 transcription factor is required for the maintenance, but not the initial specification, of the neurotransmitter identity in the caudal thalamus. Dev Dyn. 2020 May;249(5):646-655 |
1 | J:302307 Tran-Anh K, Zhang J, Nguyen-Minh VT, Fujita H, Hirata T, Sugihara I, Common Origin of the Cerebellar Dual Somatotopic Areas Revealed by Tracking Embryonic Purkinje Cell Clusters with Birthdate Tagging. eNeuro. 2020 Nov/Dec;7(6):ENEURO.0251-20.2020 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1* | J:251975 Vibulyaseck S, Fujita H, Luo Y, Tran AK, Oh-Nishi A, Ono Y, Hirano S, Sugihara I, Spatial rearrangement of Purkinje cell subsets forms the transverse and longitudinal compartmentalization in the mouse embryonic cerebellum. J Comp Neurol. 2017 Oct 1;525(14):2971-2990 |
1 | J:177905 Yamasaki T, Kawasaki H, Arakawa S, Shimizu K, Shimizu S, Reiner O, Okano H, Nishina S, Azuma N, Penninger JM, Katada T, Nishina H, Stress-Activated Protein Kinase MKK7 Regulates Axon Elongation in the Developing Cerebral Cortex. J Neurosci. 2011 Nov 16;31(46):16872-16883 |
1* | J:162778 Yang Z, Hikosaka K, Sharkar MT, Tamakoshi T, Chandra A, Wang B, Itakura T, Xue X, Uezato T, Kimura W, Miura N, The mouse forkhead gene Foxp2 modulates expression of the lung genes. Life Sci. 2010 Jul 3;87(1-2):17-25 |
1 | J:218833 Zhao H, Zhou W, Yao Z, Wan Y, Cao J, Zhang L, Zhao J, Li H, Zhou R, Li B, Wei G, Zhang Z, French CA, Dekker JD, Yang Y, Fisher SE, Tucker HO, Guo X, Foxp1/2/4 regulate endochondral ossification as a suppresser complex. Dev Biol. 2015 Feb 15;398(2):242-54 |
Foxp4 forkhead box P4 (Synonyms: 1200010K03Rik, 2310007G05Rik) | |
Results | Reference |
1* | J:125023 French CA, Groszer M, Preece C, Coupe AM, Rajewsky K, Fisher SE, Generation of mice with a conditional Foxp2 null allele. Genesis. 2007 Jul;45(7):440-6 |
2* | J:82200 Lu MM, Li S, Yang H, Morrisey EE, Foxp4: a novel member of the Foxp subfamily of winged-helix genes co-expressed with Foxp1 and Foxp2 in pulmonary and gut tissues. Mech Dev. 2002 Dec;119 Suppl 1:S197-202 |
1 | J:218833 Zhao H, Zhou W, Yao Z, Wan Y, Cao J, Zhang L, Zhao J, Li H, Zhou R, Li B, Wei G, Zhang Z, French CA, Dekker JD, Yang Y, Fisher SE, Tucker HO, Guo X, Foxp1/2/4 regulate endochondral ossification as a suppresser complex. Dev Biol. 2015 Feb 15;398(2):242-54 |
Foxq1 forkhead box Q1 (Synonyms: Hfh1, HFH-1, Hfh1l, sa) | |
Results | Reference |
1 | J:49563 Frank S, Zoll B, Mouse HNF-3/fork head homolog-1-like gene: structure, chromosomal location, and expression in adult and embryonic kidney. DNA Cell Biol. 1998 Aug;17(8):679-88 |
1 | J:138249 Goering W, Adham IM, Pasche B, Manner J, Ochs M, Engel W, Zoll B, Impairment of gastric acid secretion and increase of embryonic lethality in Foxq1-deficient mice. Cytogenet Genome Res. 2008;121(2):88-95 |
Foxs1 forkhead box S1 (Synonyms: Fkh3, Fkhl18, FREAC10) | |
Results | Reference |
1* | J:14165 Kaestner KH, Lee KH, Schlondorff J, Hiemisch H, Monaghan AP, Schutz G, Six members of the mouse forkhead gene family are developmentally regulated. Proc Natl Acad Sci U S A. 1993 Aug 15;90(16):7628-31 |
1* | J:138911 Sato Y, Baba T, Zubair M, Miyabayashi K, Toyama Y, Maekawa M, Owaki A, Mizusaki H, Sawamura T, Toshimori K, Morohashi K, Katoh-Fukui Y, Importance of forkhead transcription factor Fkhl18 for development of testicular vasculature. Mol Reprod Dev. 2008 Sep;75(9):1361-71 |
Fras1 Fraser extracellular matrix complex subunit 1 (Synonyms: bl, E130113P14Rik, mKIAA1500) | |
Results | Reference |
1* | J:117883 Chiotaki R, Petrou P, Giakoumaki E, Pavlakis E, Sitaru C, Chalepakis G, Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development. Gene Expr Patterns. 2007 Feb;7(4):381-8 |
1 | J:125902 Koster MI, Dai D, Marinari B, Sano Y, Costanzo A, Karin M, Roop DR, p63 induces key target genes required for epidermal morphogenesis. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3255-60 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
2* | J:119509 Petrou P, Chiotaki R, Dalezios Y, Chalepakis G, Overlapping and divergent localization of Frem1 and Fras1 and its functional implications during mouse embryonic development. Exp Cell Res. 2007 Mar 10;313(5):910-20 |
1* | J:137010 Petrou P, Pavlakis E, Dalezios Y, Galanopoulos VK, Chalepakis G, Basement membrane distortions impair lung lobation and capillary organization in the mouse model for fraser syndrome. J Biol Chem. 2005 Mar 18;280(11):10350-6 |
1 | J:83746 Vrontou S, Petrou P, Meyer BI, Galanopoulos VK, Imai K, Yanagi M, Chowdhury K, Scambler PJ, Chalepakis G, Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice. Nat Genet. 2003 Jun;34(2):209-14 |
Frem1 Fras1 related extracellular matrix protein 1
(Synonyms:
crf11, eye | |
Results | Reference |
1* | J:117883 Chiotaki R, Petrou P, Giakoumaki E, Pavlakis E, Sitaru C, Chalepakis G, Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development. Gene Expr Patterns. 2007 Feb;7(4):381-8 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
2* | J:119509 Petrou P, Chiotaki R, Dalezios Y, Chalepakis G, Overlapping and divergent localization of Frem1 and Fras1 and its functional implications during mouse embryonic development. Exp Cell Res. 2007 Mar 10;313(5):910-20 |
1 | J:92613 Smyth I, Du X, Taylor MS, Justice MJ, Beutler B, Jackson IJ, The extracellular matrix gene Frem1 is essential for the normal adhesion of the embryonic epidermis. Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13560-5 |
1* | J:177282 Vissers LE, Cox TC, Maga AM, Short KM, Wiradjaja F, Janssen IM, Jehee F, Bertola D, Liu J, Yagnik G, Sekiguchi K, Kiyozumi D, van Bokhoven H, Marcelis C, Cunningham ML, Anderson PJ, Boyadjiev SA, Passos-Bueno MR, Veltman JA, Smyth I, Buckley MF, RoscioliT, Heterozygous mutations of FREM1 are associated with an increased risk of isolated metopic craniosynostosis in humans and mice. PLoS Genet. 2011 Sep;7(9):e1002278 |
Frem2 Fras1 related extracellular matrix protein 2 (Synonyms: 6030440P17Rik, 8430406N05Rik, b2b1562Clo, my, ne) | |
Results | Reference |
1* | J:117883 Chiotaki R, Petrou P, Giakoumaki E, Pavlakis E, Sitaru C, Chalepakis G, Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development. Gene Expr Patterns. 2007 Feb;7(4):381-8 |
Frem3 Fras1 related extracellular matrix protein 3 (Synonyms: LOC333315) | |
Results | Reference |
1* | J:117883 Chiotaki R, Petrou P, Giakoumaki E, Pavlakis E, Sitaru C, Chalepakis G, Spatiotemporal distribution of Fras1/Frem proteins during mouse embryonic development. Gene Expr Patterns. 2007 Feb;7(4):381-8 |
Frmd6 FERM domain containing 6 (Synonyms: 2610019M19Rik, 4930488L10Rik) | |
Results | Reference |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
Frmd7 FERM domain containing 7 (Synonyms: EG665849, LOC385354) | |
Results | Reference |
1* | J:156039 Self J, Haitchi HM, Griffiths H, Holgate ST, Davies DE, Lotery A, Frmd7 expression in developing mouse brain. Eye (Lond). 2010 Jan;24(1):165-9 |
Frs2 fibroblast growth factor receptor substrate 2 (Synonyms: C330018A15Rik, Frs2alpha, SNT1) | |
Results | Reference |
1* | J:69784 McDougall K, Kubu C, Verdi JM, Meakin SO, Developmental expression patterns of the signaling adapters FRS-2 and FRS-3 during early embryogenesis. Mech Dev. 2001 May;103(1-2):145-8 |
Frs3 fibroblast growth factor receptor substrate 3 (Synonyms: 4930417B13Rik, Frs2beta, MGC:25496, SNT2) | |
Results | Reference |
1* | J:69784 McDougall K, Kubu C, Verdi JM, Meakin SO, Developmental expression patterns of the signaling adapters FRS-2 and FRS-3 during early embryogenesis. Mech Dev. 2001 May;103(1-2):145-8 |
Frzb frizzled-related protein (Synonyms: fritz, Frp, frzb-1, Sfrp3) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1 | J:184011 John A, Brylka H, Wiegreffe C, Simon R, Liu P, Juttner R, Crenshaw EB 3rd, Luyten FP, Jenkins NA, Copeland NG, Birchmeier C, Britsch S, Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. Development. 2012 May;139(10):1831-41 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1* | J:268254 Rich CA, Perera SN, Andratschke J, Stolt CC, Buehler DP, Southard-Smith EM, Wegner M, Britsch S, Baker CVH, Olfactory ensheathing cells abutting the embryonic olfactory bulb express Frzb, whose deletion disrupts olfactory axon targeting. Glia. 2018 Dec;66(12):2617-2631 |
1 | J:207050 Zhao X, Huang H, Chen Y, Liu Y, Zhang Z, Ma Q, Qiu M, Dynamic expression of secreted Frizzled-related protein 3 (sFRP3) in the developing mouse spinal cord and dorsal root ganglia. Neuroscience. 2013 Sep 17;248:594-601 |
Fscn1 fascin actin-bundling protein 1 (Synonyms: Fan1, fascin-1) | |
Results | Reference |
1* | J:93153 De Arcangelis A, Georges-Labouesse E, Adams JC, Expression of fascin-1, the gene encoding the actin-bundling protein fascin-1, during mouse embryogenesis. Gene Expr Patterns. 2004 Oct;4(6):637-43 |
1 | J:279389 Miao Q, Hill MC, Chen F, Mo Q, Ku AT, Ramos C, Sock E, Lefebvre V, Nguyen H, SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair. Nat Commun. 2019 Sep 6;10(1):4042 |
1* | J:214682 Wei Z, Sun M, Liu X, Zhang J, Jin Y, Rufy3, a protein specifically expressed in neurons, interacts with actin-bundling protein Fascin to control the growth of axons. J Neurochem. 2014 Sep;130(5):678-92 |
Fshb follicle stimulating hormone beta (Synonyms: FSH, Fshbeta) | |
Results | Reference |
1* | J:19457 Japon MA, Rubinstein M, Low MJ, In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development. J Histochem Cytochem. 1994 Aug;42(8):1117-25 |
1 | J:140899 Million Passe CM, White CR, King MW, Quirk PL, Iovanna JL, Quirk CC, Loss of the protein NUPR1 (p8) leads to delayed LHB expression, delayed ovarian maturation, and testicular development of a sertoli-cell-only syndrome-like phenotype in mice. Biol Reprod. 2008 Oct;79(4):598-607 |
1 | J:108374 Vesper AH, Raetzman LT, Camper SA, Role of prophet of Pit1 (PROP1) in gonadotrope differentiation and puberty. Endocrinology. 2006 Apr;147(4):1654-63 |
Fst follistatin | |
Results | Reference |
1 | J:307093 Amato CM, Yao HH, Developmental and sexual dimorphic atlas of the prenatal mouse external genitalia at the single-cell level. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2103856118 |
1 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
1 | J:149988 Beites CL, Hollenbeck PL, Kim J, Lovell-Badge R, Lander AD, Calof AL, Follistatin modulates a BMP autoregulatory loop to control the size and patterning of sensory domains in the developing tongue. Development. 2009 Jul;136(13):2187-97 |
1 | J:327415 Jing J, Feng J, Yuan Y, Guo T, Lei J, Pei F, Ho TV, Chai Y, Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022 Aug 16;13(1):4803 |
1* | J:199186 Juuri E, Saito K, Lefebvre S, Michon F, Establishment of crown-root domain borders in mouse incisor. Gene Expr Patterns. 2013 Oct;13(7):255-64 |
1* | J:168597 Kashimada K, Pelosi E, Chen H, Schlessinger D, Wilhelm D, Koopman P, FOXL2 and BMP2 act cooperatively to regulate follistatin gene expression during ovarian development. Endocrinology. 2011 Jan;152(1):272-80 |
1 | J:147995 Kawauchi S, Kim J, Santos R, Wu HH, Lander AD, Calof AL, Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11. Development. 2009 May;136(9):1453-64 |
1 | J:336410 Koo HY, Kim MA, Min H, Hwang JY, Prajapati-DiNubila M, Kim KS, Matzuk MM, Park JW, Doetzlhofer A, Kim UK, Bok J, Follistatin regulates the specification of the apical cochlea responsible for low-frequency hearing in mammals. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2213099120 |
1 | J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670 |
1 | J:246806 Li Y, Zhang L, Hu Y, Chen M, Han F, Qin Y, Chen M, Cui X, Duo S, Tang F, Gao F, beta-Catenin directs the transformation of testis Sertoli cells to ovarian granulosa-like cells by inducing Foxl2 expression. J Biol Chem. 2017 Oct 27;292(43):17577-17586 |
1 | J:63347 Maldonado TS, Kadison AS, Crisera CA, Grau JB, Alkasab SL, Longaker MT, Gittes GK, Ontogeny of activin B and follistatin in developing embryonic mouse pancreas: implications for lineage selection. J Gastrointest Surg. 2000 May-Jun;4(3):269-75 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:160264 Nakatomi M, Wang XP, Key D, Lund JJ, Turbe-Doan A, Kist R, Aw A, Chen Y, Maas RL, Peters H, Genetic interactions between Pax9 and Msx1 regulate lip development and several stages of tooth morphogenesis. Dev Biol. 2010 Apr 15;340(2):438-49 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:288236 Takahashi M, Ikeda K, Ohmuraya M, Nakagawa Y, Sakuma T, Yamamoto T, Kawakami K, Six1 is required for signaling center formation and labial-lingual asymmetry in developing lower incisors. Dev Dyn. 2020 Apr 3; |
1 | J:91704 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Wankell M, Werner S, Thesleff I, Modulation of activin/bone morphogenetic protein signaling by follistatin is required for the morphogenesis of mouse molar teeth. Dev Dyn. 2004 Sep;231(1):98-108 |
1 | J:94518 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Werner S, Thesleff I, Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation. Dev Cell. 2004 Nov;7(5):719-30 |
1* | J:173972 Zhao H, Li S, Han D, Kaartinen V, Chai Y, Alk5-mediated transforming growth factor beta signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol. 2011 May;31(10):2079-89 |
Fstl1 follistatin-like 1 (Synonyms: TSC-36) | |
Results | Reference |
1 | J:302828 Liu R, Yang Y, Shen J, Chen H, Zhang Q, Ba R, Wei Y, Li KC, Zhang X, Zhao C, Fstl1 is involved in the regulation of radial glial scaffold development. Mol Brain. 2015 Sep 17;8:53 |
1 | J:176532 Sylva M, Li VS, Buffing AA, van Es JH, van den Born M, van der Velden S, Gunst Q, Koolstra JH, Moorman AF, Clevers H, van den Hoff MJ, The BMP antagonist follistatin-like 1 is required for skeletal and lung organogenesis. PLoS One. 2011;6(8):e22616 |
2 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
1* | J:152417 Yang Y, Liu J, Mao H, Hu YA, Yan Y, Zhao C, The expression pattern of Follistatin-like 1 in mouse central nervous system development. Gene Expr Patterns. 2009 Oct;9(7):532-40 |
Fstl3 follistatin-like 3 (Synonyms: E030038F23Rik, Flrg) | |
Results | Reference |
1 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
Fstl4 follistatin-like 4 (Synonyms: B230374F23Rik, SPIG1) | |
Results | Reference |
1 | J:223316 Sun LO, Brady CM, Cahill H, Al-Khindi T, Sakuta H, Dhande OS, Noda M, Huberman AD, Nathans J, Kolodkin AL, Functional assembly of accessory optic system circuitry critical for compensatory eye movements. Neuron. 2015 May 20;86(4):971-84 |
Fstl5 follistatin-like 5 (Synonyms: 9130207J01Rik) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Fubp1 far upstream element (FUSE) binding protein 1 (Synonyms: 9530027K12Rik, FBP, Fubp, Fubp4) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Fundc1 FUN14 domain containing 1 (Synonyms: 1500005J14Rik, 1810033P05Rik) | |
Results | Reference |
1 | J:356661 Esteban-Martinez L, Sierra-Filardi E, McGreal RS, Salazar-Roa M, Marino G, Seco E, Durand S, Enot D, Grana O, Malumbres M, Cvekl A, Cuervo AM, Kroemer G, Boya P, Programmed mitophagy is essential for the glycolytic switch during cell differentiation. EMBO J. 2017 Jun 14;36(12):1688-1706 |
Fus fused in sarcoma (Synonyms: D430004D17Rik, D930039C12Rik, hnRNP P2, pigpen, Tls, translocated in liposarcoma) | |
Results | Reference |
1* | J:85485 Alappat SR, Zhang M, Zhao X, Alliegro MA, Alliegro MC, Burdsal CA, Mouse pigpen encodes a nuclear protein whose expression is developmentally regulated during craniofacial morphogenesis. Dev Dyn. 2003 Sep;228(1):59-71 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Fut4 fucosyltransferase 4 (Synonyms: 3-fucosyl-N-acetyl-lactosamine epitope, FAL, FucT-IV, LeX, Ssea1, SSEA-1) | |
Results | Reference |
1* | J:87456 Fox N, Damjanov I, Martinez-Hernandez A, Knowles BB, Solter D, Immunohistochemical localization of the early embryonic antigen (SSEA-1) in postimplantation mouse embryos and fetal and adult tissues. Dev Biol. 1981 Apr 30;83(2):391-8 |
1 | J:329367 Kudo T, Fujii T, Ikegami S, Inokuchi K, Takayama Y, Ikehara Y, Nishihara S, Togayachi A, Takahashi S, Tachibana K, Yuasa S, Narimatsu H, Mice lacking alpha1,3-fucosyltransferase IX demonstrate disappearance of Lewis x structure in brain and increased anxiety-like behaviors. Glycobiology. 2007 Jan;17(1):1-9 |
1* | J:100603 Lin L, Cheung AW, Chan SO, Chiasmatic neurons in the ventral diencephalon of mouse embryos--changes in arrangement and heterogeneity in surface antigen expression. Brain Res Dev Brain Res. 2005 Aug 8;158(1-2):1-12 |
Fxn frataxin (Synonyms: Frda) | |
Results | Reference |
1* | J:43296 Jiralerspong S, Liu Y, Montermini L, Stifani S, Pandolfo M, Frataxin shows developmentally regulated tissue-specific expression in the mouse embryo. Neurobiol Dis. 1997;4(2):103-13 |
1* | J:42050 Koutnikova H, Campuzano V, Foury F, Dolle P, Cazzalini O, Koenig M, Studies of human, mouse and yeast homologues indicate a mitochondrial function for frataxin. Nat Genet. 1997 Aug;16(4):345-51 |
Fxr1 FMR1 autosomal homolog 1 (Synonyms: 1110050J02Rik, 9530073J07Rik, Fxr1h, Fxr1p) | |
Results | Reference |
1 | J:30134 Coy JF, Sedlacek Z, Bachner D, Hameister H, Joos S, Lichter P, Delius H, Poustka A, Highly conserved 3' UTR and expression pattern of FXR1 points to a divergent gene regulation of FXR1 and FMR1. Hum Mol Genet. 1995 Dec;4(12):2209-18 |
1* | J:259125 Yang J, Hung LH, Licht T, Kostin S, Looso M, Khrameeva E, Bindereif A, Schneider A, Braun T, RBM24 is a major regulator of muscle-specific alternative splicing. Dev Cell. 2014 Oct 13;31(1):87-99 |
Fxyd5 FXYD domain-containing ion transport regulator 5 (Synonyms: dysadherin, EF-8, Oit2) | |
Results | Reference |
1 | J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132 |
Fxyd7 FXYD domain-containing ion transport regulator 7 (Synonyms: 1110035I01Rik) | |
Results | Reference |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Fyn Fyn proto-oncogene (Synonyms: Src Kinase p59) | |
Results | Reference |
1 | J:101055 Kuo G, Arnaud L, Kronstad-O'Brien P, Cooper JA, Absence of Fyn and Src causes a reeler-like phenotype. J Neurosci. 2005 Sep 14;25(37):8578-86 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1* | J:55945 Wang JP, Chuang SM, Shen CL, Chen ST, Expression of Src family during development of the mouse nervous system. Biomed Res. 1998 OCT;19(5):315-325 |
1 | J:180006 Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T, NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54 |
Fzd1 frizzled class receptor 1 (Synonyms: Fz1, FZ-1) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
2 | J:311811 Trowe MO, Airik R, Weiss AC, Farin HF, Foik AB, Bettenhausen E, Schuster-Gossler K, Taketo MM, Kispert A, Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter. Development. 2012 Sep;139(17):3099-108 |
1 | J:99178 Wang Z, Shu W, Lu MM, Morrisey EE, Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5. Mol Cell Biol. 2005 Jun;25(12):5022-30 |
1* | J:105879 Zhang TJ, Hoffman BG, Ruiz de Algara T, Helgason CD, SAGE reveals expression of Wnt signalling pathway members during mouse prostate development. Gene Expr Patterns. 2006 Mar;6(3):310-24 |
1 | J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687 |
Fzd2 frizzled class receptor 2 (Synonyms: Fz10, Mfz10, Mfz10a) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1* | J:91248 Reddy ST, Andl T, Lu MM, Morrisey EE, Millar SE, Expression of frizzled genes in developing and postnatal hair follicles. J Invest Dermatol. 2004 Aug;123(2):275-82 |
Fzd3 frizzled class receptor 3 (Synonyms: D930050A07Rik, Fz3) | |
Results | Reference |
1 | J:169444 Armstrong A, Ryu YK, Chieco D, Kuruvilla R, Frizzled3 Is Required for Neurogenesis and Target Innervation during Sympathetic Nervous System Development. J Neurosci. 2011 Feb 16;31(7):2371-81 |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:280404 Ghimire SR, Deans MR, Frizzled3 and Frizzled6 Cooperate with Vangl2 to Direct Cochlear Innervation by Type II Spiral Ganglion Neurons. J Neurosci. 2019 Oct 9;39(41):8013-8023 |
1 | J:264107 Ghimire SR, Ratzan EM, Deans MR, A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea. Development. 2018 Jun 14;145(12):dev159012 |
1* | J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20 |
1 | J:197538 Sasselli V, Boesmans W, Vanden Berghe P, Tissir F, Goffinet AM, Pachnis V, Planar cell polarity genes control the connectivity of enteric neurons. J Clin Invest. 2013 Apr 1;123(4):1763-72 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Fzd4 frizzled class receptor 4 (Synonyms: Fz4) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
1* | J:91248 Reddy ST, Andl T, Lu MM, Morrisey EE, Millar SE, Expression of frizzled genes in developing and postnatal hair follicles. J Invest Dermatol. 2004 Aug;123(2):275-82 |
1 | J:99178 Wang Z, Shu W, Lu MM, Morrisey EE, Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5. Mol Cell Biol. 2005 Jun;25(12):5022-30 |
Fzd5 frizzled class receptor 5 (Synonyms: 5330434N09Rik, Fz5) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:136390 Liu C, Wang Y, Smallwood PM, Nathans J, An essential role for Frizzled5 in neuronal survival in the parafascicular nucleus of the thalamus. J Neurosci. 2008 May 28;28(22):5641-53 |
1 | J:350084 Zhang L, Liu X, Li W, Liu K, Zhang J, Liu X, Wang J, Integrative transcriptomic profiling of ncRNAs and mRNAs in developing mouse lens. Front Genet. 2024;15:1405715 |
Fzd6 frizzled class receptor 6 (Synonyms: Fz6) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1* | J:198837 Cui CY, Klar J, Georgii-Heming P, Frojmark AS, Baig SM, Schlessinger D, Dahl N, Frizzled6 deficiency disrupts the differentiation process of nail development. J Invest Dermatol. 2013 Aug;133(8):1990-7 |
1 | J:145627 Devenport D, Fuchs E, Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol. 2008 Nov;10(11):1257-68 |
1* | J:178042 Frojmark AS, Schuster J, Sobol M, Entesarian M, Kilander MB, Gabrikova D, Nawaz S, Baig SM, Schulte G, Klar J, Dahl N, Mutations in Frizzled 6 cause isolated autosomal-recessive nail dysplasia. Am J Hum Genet. 2011 Jun 10;88(6):852-60 |
1 | J:329316 Kunimoto K, Weiner AT, Axelrod JD, Vladar EK, Distinct overlapping functions for Prickle1 and Prickle2 in the polarization of the airway epithelium. Front Cell Dev Biol. 2022;10:976182 |
1* | J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20 |
Fzd7 frizzled class receptor 7 (Synonyms: Fz7) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:99178 Wang Z, Shu W, Lu MM, Morrisey EE, Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5. Mol Cell Biol. 2005 Jun;25(12):5022-30 |
1* | J:105879 Zhang TJ, Hoffman BG, Ruiz de Algara T, Helgason CD, SAGE reveals expression of Wnt signalling pathway members during mouse prostate development. Gene Expr Patterns. 2006 Mar;6(3):310-24 |
Fzd8 frizzled class receptor 8 (Synonyms: Fz8, mFZ8) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:181885 Liu C, Bakeri H, Li T, Swaroop A, Regulation of retinal progenitor expansion by Frizzled receptors: implications for microphthalmia and retinal coloboma. Hum Mol Genet. 2012 Apr 15;21(8):1848-60 |
1 | J:313267 Morenilla-Palao C, Lopez-Cascales MT, Lopez-Atalaya JP, Baeza D, Calvo-Diaz L, Barco A, Herrera E, A Zic2-regulated switch in a noncanonical Wnt/betacatenin pathway is essential for the formation of bilateral circuits. Sci Adv. 2020 Nov;6(46) |
1* | J:91248 Reddy ST, Andl T, Lu MM, Morrisey EE, Millar SE, Expression of frizzled genes in developing and postnatal hair follicles. J Invest Dermatol. 2004 Aug;123(2):275-82 |
1* | J:131546 Rinn JL, Wang JK, Allen N, Brugmann SA, Mikels AJ, Liu H, Ridky TW, Stadler HS, Nusse R, Helms JA, Chang HY, A dermal HOX transcriptional program regulates site-specific epidermal fate. Genes Dev. 2008 Feb 1;22(3):303-7 |
Fzd9 frizzled class receptor 9 (Synonyms: frizzled 9, Fz9, mfz9) | |
Results | Reference |
1 | J:236211 Aviles EC, Pinto C, Hanna P, Ojeda J, Perez V, De Ferrari GV, Zamorano P, Albistur M, Sandoval D, Henriquez JP, Frizzled-9 impairs acetylcholine receptor clustering in skeletal muscle cells. Front Cell Neurosci. 2014;8:110 |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1* | J:91248 Reddy ST, Andl T, Lu MM, Morrisey EE, Millar SE, Expression of frizzled genes in developing and postnatal hair follicles. J Invest Dermatol. 2004 Aug;123(2):275-82 |
2 | J:72321 Van Raay TJ, Wang YK, Stark MR, Rasmussen JT, Francke U, Vetter ML, Rao MS, frizzled 9 is expressed in neural precursor cells in the developing neural tube. Dev Genes Evol. 2001 Sep;211(8-9):453-7 |
Fzd10 frizzled class receptor 10 (Synonyms: Fz-10) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:217500 Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D, Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60 |
1 | J:99178 Wang Z, Shu W, Lu MM, Morrisey EE, Wnt7b activates canonical signaling in epithelial and vascular smooth muscle cells through interactions with Fzd1, Fzd10, and LRP5. Mol Cell Biol. 2005 Jun;25(12):5022-30 |
1* | J:144241 Yan Y, Li Y, Hu C, Gu X, Liu J, Hu YA, Yang Y, Wei Y, Zhao C, Expression of Frizzled10 in mouse central nervous system. Gene Expr Patterns. 2009 Mar;9(3):173-177 |
G0s2 G0/G1 switch gene 2 | |
Results | Reference |
1* | J:51222 Bachner D, Ahrens M, Schroder D, Hoffmann A, Lauber J, Betat N, Steinert P, Flohe L, Gross G, Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T1/2). Dev Dyn. 1998 Dec;213(4):398-411 |
G2e3 G2/M-phase specific E3 ubiquitin ligase (Synonyms: 6030408C04Rik, D930034K21Rik, mKIAA1333) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
G3bp2 G3BP stress granule assembly factor 2 (Synonyms: E430034L04Rik, G3BP, G3BP2) | |
Results | Reference |
1 | J:282136 Kato Y, Iwamori T, Ninomiya Y, Kohda T, Miyashita J, Sato M, Saga Y, ELAVL2-directed RNA regulatory network drives the formation of quiescent primordial follicles. EMBO Rep. 2019 Dec 5;20(12):e48251 |
2* | J:299510 Wang JJ, Ge W, Zhai QY, Liu JC, Sun XW, Liu WX, Li L, Lei CZ, Dyce PW, De Felici M, Shen W, Single-cell transcriptome landscape of ovarian cells during primordial follicle assembly in mice. PLoS Biol. 2020 Dec;18(12):e3001025 |
G6pc1 glucose-6-phosphatase catalytic subunit 1 (Synonyms: G6Pase, G6pc, G6pt, Glc-6-Pase, Glc-6-Pase-alpha) | |
Results | Reference |
1* | J:146970 Li T, Huang J, Jiang Y, Zeng Y, He F, Zhang MQ, Han Z, Zhang X, Multi-stage analysis of gene expression and transcription regulation in C57/B6 mouse liver development. Genomics. 2009 Mar;93(3):235-42 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
1* | J:272586 Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, Yamamoto T, Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019 Feb 15;146(4):dev168146 |
G6pc2 glucose-6-phosphatase, catalytic, 2 (Synonyms: G6pc-rs, IGRP, islet specific glucose-6-phosphatase) | |
Results | Reference |
1 | J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
G6pc3 glucose 6 phosphatase, catalytic, 3 (Synonyms: 0710001K01Rik) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
G6pdx glucose-6-phosphate dehydrogenase X-linked (Synonyms: G28A, G6pd, Gpdx) | |
Results | Reference |
2 | J:326543 Jiang A, Guo H, Jiang X, Tao J, Wu W, Liu H, G6PD Deficiency Is Crucial for Insulin Signaling Activation in Skeletal Muscle. Int J Mol Sci. 2022 Jul 4;23(13) |
Gaa glucosidase, alpha, acid (Synonyms: E430018M07Rik) | |
Results | Reference |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
Gab1 growth factor receptor bound protein 2-associated protein 1 | |
Results | Reference |
1 | J:310318 Li H, Tao C, Cai Z, Hertzler-Schaefer K, Collins TN, Wang F, Feng GS, Gotoh N, Zhang X, Frs2alpha and Shp2 signal independently of Gab to mediate FGF signaling in lens development. J Cell Sci. 2014 Feb 1;127(Pt 3):571-82 |
Gabarapl1 GABA type A receptor associated protein like 1 (Synonyms: 3110025G09Rik, 9130422N19Rik, Apg8l, Atg8l, GECI) | |
Results | Reference |
2* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
Gabarapl2 GABA type A receptor associated protein like 2 (Synonyms: 0610012F20Rik, 2900019O08Rik, GATE-16, Gef2) | |
Results | Reference |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
Gabbr1 gamma-aminobutyric acid type B receptor subunit 1 (Synonyms: GABAB1, GABAbR1) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Gabbr2 gamma-aminobutyric acid type B receptor subunit 2 (Synonyms: Gababr2, GB2, Gpr51, LOC242425) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
2* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Gabpb1 GA repeat binding protein, beta 1 (Synonyms: BABPB2, E4TF1, E4TF1-47, E4TF1-53, E4Tf1B, GABPB1-1, GABPB1-2, NRF2B1, NRF2B2) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Gabpb2 GA repeat binding protein, beta 2 (Synonyms: 1810015F01Rik, 9430006E19Rik, A430024B14Rik, Gabpb2-1) | |
Results | Reference |
1 | J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39 |
1 | J:206588 Mardaryev AN, Gdula MR, Yarker JL, Emelianov VN, Poterlowicz K, Sharov AA, Sharova TY, Scarpa JA, Chambon P, Botchkarev VA, Fessing MY, p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells. Development. 2014 Jan;141(1):101-11 |
Gabra1 gamma-aminobutyric acid type A receptor subunit alpha 1 (Synonyms: GABAA alpha 1, GABAAR alpha1, Gabra-1) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Gabra2 gamma-aminobutyric acid type A receptor subunit alpha 2 (Synonyms: C630048P16Rik, Gabra-2) | |
Results | Reference |
2 | J:25970 Chang CC, Luntz-Leybman V, Evans JE, Rotter A, Frostholm A, Developmental changes in the expression of gamma-aminobutyric acidA/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex. J Comp Neurol. 1995 Jun 12;356(4):615-28 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Gabra3 gamma-aminobutyric acid type A receptor subunit alpha 3 (Synonyms: Gabra-3) | |
Results | Reference |
2 | J:25970 Chang CC, Luntz-Leybman V, Evans JE, Rotter A, Frostholm A, Developmental changes in the expression of gamma-aminobutyric acidA/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex. J Comp Neurol. 1995 Jun 12;356(4):615-28 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Gabra4 gamma-aminobutyric acid type A receptor subunit alpha 4 (Synonyms: Gabra-4) | |
Results | Reference |
2 | J:25970 Chang CC, Luntz-Leybman V, Evans JE, Rotter A, Frostholm A, Developmental changes in the expression of gamma-aminobutyric acidA/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex. J Comp Neurol. 1995 Jun 12;356(4):615-28 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Gabra5 gamma-aminobutyric acid type A receptor subunit alpha 5 (Synonyms: A230018I05Rik) | |
Results | Reference |
2 | J:25970 Chang CC, Luntz-Leybman V, Evans JE, Rotter A, Frostholm A, Developmental changes in the expression of gamma-aminobutyric acidA/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex. J Comp Neurol. 1995 Jun 12;356(4):615-28 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Gabra6 gamma-aminobutyric acid type A receptor subunit alpha 6 (Synonyms: alpha6, GABA-ARalpha6, Gabra-6) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Gabrb1 gamma-aminobutyric acid type A receptor subunit beta 1 (Synonyms: B230208N19Rik, Gabrb-1) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Gabrb2 gamma-aminobutyric acid type A receptor subunit beta 2 (Synonyms: C030002O17Rik, C030021G16Rik, Gabrb-2) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Gabrb3 GABRB3, gamma-aminobutyric acid type A receptor subunit beta 3 (Synonyms: A230092K12Rik, beta3, Gabrb-3) | |
Results | Reference |
2 | J:25970 Chang CC, Luntz-Leybman V, Evans JE, Rotter A, Frostholm A, Developmental changes in the expression of gamma-aminobutyric acidA/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex. J Comp Neurol. 1995 Jun 12;356(4):615-28 |
1* | J:12553 Culiat CT, Stubbs L, Nicholls RD, Montgomery CS, Russell LB, Johnson DK, Rinchik EM, Concordance between isolated cleft palate in mice and alterations within a region including the gene encoding the beta 3 subunit of the type A gamma-aminobutyric acid receptor. Proc Natl Acad Sci U S A. 1993 Jun 1;90(11):5105-9 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
2* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Gabrd gamma-aminobutyric acid (GABA) A receptor, subunit delta | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Gabre gamma-aminobutyric acid (GABA) A receptor, subunit epsilon | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:52383 Tobet SA, Henderson RG, Whiting PJ, Sieghart W, Special relationship of gamma-aminobutyric acid to the ventromedial nucleus of the hypothalamus during embryonic development. J Comp Neurol. 1999 Mar 1;405(1):88-98 |
Gabrg1 gamma-aminobutyric acid type A receptor subunit gamma 1 (Synonyms: GabaA) | |
Results | Reference |
2 | J:25970 Chang CC, Luntz-Leybman V, Evans JE, Rotter A, Frostholm A, Developmental changes in the expression of gamma-aminobutyric acidA/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex. J Comp Neurol. 1995 Jun 12;356(4):615-28 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Gabrg2 gamma-aminobutyric acid type A receptor, subunit gamma 2 (Synonyms: GABAA-R, Gabrg-2, gamma2) | |
Results | Reference |
1 | J:25970 Chang CC, Luntz-Leybman V, Evans JE, Rotter A, Frostholm A, Developmental changes in the expression of gamma-aminobutyric acidA/benzodiazepine receptor subunit mRNAs in the murine inferior olivary complex. J Comp Neurol. 1995 Jun 12;356(4):615-28 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Gabrg3 gamma-aminobutyric acid type A receptor, subunit gamma 3 (Synonyms: B230362M20Rik, Gabrg-3) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Gabrp gamma-aminobutyric acid type A receptor subunit pi | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Gabrq gamma-aminobutyric acid type A receptor subunit theta | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Gabrr1 gamma-aminobutyric acid type A receptor subunit rho 1 (Synonyms: GABA-C) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Gabrr2 gamma-aminobutyric acid type A receptor subunit rho 2 | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Gabrr3 gamma-aminobutyric acid type A receptor subunit rho 3 | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Gad1 glutamate decarboxylase 1 (Synonyms: EP10, Gad-1, GAD25, GAD44, GAD67, Z49976) | |
Results | Reference |
2 | J:185533 Achim K, Peltopuro P, Lahti L, Li J, Salminen M, Partanen J, Distinct developmental origins and regulatory mechanisms for GABAergic neurons associated with dopaminergic nuclei in the ventral mesodiencephalic region. Development. 2012 Jul;139(13):2360-70 |
1 | J:225119 Aida T, Ito Y, Takahashi YK, Tanaka K, Overstimulation of NMDA receptors impairs early brain development in vivo. PLoS One. 2012;7(5):e36853 |
1 | J:50421 Alcantara S, Ruiz M, D'Arcangelo G, Ezan F, de Lecea L, Curran T , Sotelo C , Soriano E, Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse. J Neurosci. 1998 Oct 1;18(19):7779-99 |
2* | J:173124 Aujla PK, Bora A, Monahan P, Sweedler JV, Raetzman LT, The Notch effector gene Hes1 regulates migration of hypothalamic neurons, neuropeptide content and axon targeting to the pituitary. Dev Biol. 2011 May 1;353(1):61-71 |
1 | J:183848 Benadiba C, Magnani D, Niquille M, Morle L, Valloton D, Nawabi H, Ait-Lounis A, Otsmane B, Reith W, Theil T, Hornung JP, Lebrand C, Durand B, The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development. PLoS Genet. 2012 Mar;8(3):e1002606 |
1 | J:119559 Bouwman J, Spijker S, Schut D, Wachtler B, Ylstra B, Smit AB, Verhage M, Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse. J Neurochem. 2006 Oct;99(1):84-96 |
1 | J:300487 Chai G, Webb A, Li C, Antaki D, Lee S, Breuss MW, Lang N, Stanley V, Anzenberg P, Yang X, Marshall T, Gaffney P, Wierenga KJ, Chung BH, Tsang MH, Pais LS, Lovgren AK, VanNoy GE, Rehm HL, Mirzaa G, Leon E, Diaz J, Neumann A, Kalverda AP, Manfield IW, Parry DA, Logan CV, Johnson CA, Bonthron DT, Valleley EMA, Issa MY, Abdel-Ghafar SF, Abdel-Hamid MS, Jennings P, Zaki MS, Sheridan E, Gleeson JG, Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 Jan 20;109(2):241-256.e9 |
1 | J:90585 Cheng L, Arata A, Mizuguchi R, Qian Y, Karunaratne A, Gray PA, Arata S, Shirasawa S, Bouchard M, Luo P, Chen CL, Busslinger M, Goulding M, Onimaru H, Ma Q, Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates. Nat Neurosci. 2004 May;7(5):510-7 |
1* | J:98171 Cobos I, Broccoli V, Rubenstein JL, The vertebrate ortholog of Aristaless is regulated by Dlx genes in the developing forebrain. J Comp Neurol. 2005 Mar 14;483(3):292-303 |
1 | J:188332 Delogu A, Sellers K, Zagoraiou L, Bocianowska-Zbrog A, Mandal S, Guimera J, Rubenstein JL, Sugden D, Jessell T, Lumsden A, Subcortical visual shell nuclei targeted by ipRGCs develop from a Sox14+-GABAergic progenitor and require Sox14 to regulate daily activity rhythms. Neuron. 2012 Aug 23;75(4):648-62 |
1 | J:268511 Fujiyama T, Miyashita S, Tsuneoka Y, Kanemaru K, Kakizaki M, Kanno S, Ishikawa Y, Yamashita M, Owa T, Nagaoka M, Kawaguchi Y, Yanagawa Y, Magnuson MA, Muratani M, Shibuya A, Nabeshima YI, Yanagisawa M, Funato H, Hoshino M, Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain. Cell Rep. 2018 Jul 3;24(1):79-94 |
2 | J:104420 Glasgow SM, Henke RM, Macdonald RJ, Wright CV, Johnson JE, Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn. Development. 2005 Dec;132(24):5461-9 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:119019 Gutin G, Fernandes M, Palazzolo L, Paek H, Yu K, Ornitz DM, McConnell SK, Hebert JM, FGF signalling generates ventral telencephalic cells independently of SHH. Development. 2006 Aug;133(15):2937-46 |
1 | J:304874 Hatanaka Y, Matsumoto T, Yanagawa Y, Fujisawa H, Murakami F, Masu M, Distinct roles of neuropilin 1 signaling for radial and tangential extension of callosal axons. J Comp Neurol. 2009 May 20;514(3):215-25 |
1 | J:81763 Hebert JM, Lin M, Partanen J, Rossant J, McConnell SK, FGF signaling through FGFR1 is required for olfactory bulb morphogenesis. Development. 2003 Mar;130(6):1101-11 |
1 | J:170540 Jeong Y, Dolson DK, Waclaw RR, Matise MP, Sussel L, Campbell K, Kaestner KH, Epstein DJ, Spatial and temporal requirements for sonic hedgehog in the regulation of thalamic interneuron identity. Development. 2011 Feb;138(3):531-41 |
1 | J:336092 Knowles SJ, Stafford AM, Zaman T, Angara K, Williams MR, Newbern JM, Vogt D, Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs. Development. 2023 May 15;150(10):dev201371 |
1 | J:213853 Krocher T, Rockle I, Diederichs U, Weinhold B, Burkhardt H, Yanagawa Y, Gerardy-Schahn R, Hildebrandt H, A crucial role for polysialic acid in developmental interneuron migration and the establishment of interneuron densities in the mouse prefrontal cortex. Development. 2014 Aug;141(15):3022-32 |
3* | J:127151 Kwakowsky A, Schwirtlich M, Zhang Q, Eisenstat DD, Erdelyi F, Baranyi M, Katarova ZD, Szabo G, GAD isoforms exhibit distinct spatiotemporal expression patterns in the developing mouse lens: Correlation with Dlx2 and Dlx5. Dev Dyn. 2007 Dec;236(12):3532-44 |
1 | J:244498 Lee B, Lee M, Song S, Loi LD, Lam DT, Yoon J, Baek K, Curtis DJ, Jeong Y, Specification of neurotransmitter identity by Tal1 in thalamic nuclei. Dev Dyn. 2017 Oct;246(10):749-758 |
1 | J:328992 Manuel M, Tan KB, Kozic Z, Molinek M, Marcos TS, Razak MFA, Dobolyi D, Dobie R, Henderson BEP, Henderson NC, Chan WK, Daw MI, Mason JO, Price DJ, Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals. PLoS Biol. 2022 Sep;20(9):e3001563 |
1 | J:275078 Minocha S, Valloton D, Arsenijevic Y, Cardinaux JR, Guidi R, Hornung JP, Lebrand C, Nkx2.1 regulates the generation of telencephalic astrocytes during embryonic development. Sci Rep. 2017 Mar 7;7:43093 |
1 | J:304361 Mitsogiannis MD, Pancho A, Aerts T, Sachse SM, Vanlaer R, Noterdaeme L, Schmucker D, Seuntjens E, Subtle Roles of Down Syndrome Cell Adhesion Molecules in Embryonic Forebrain Development and Neuronal Migration. Front Cell Dev Biol. 2020;8:624181 |
1 | J:258875 Mona B, Uruena A, Kollipara RK, Ma Z, Borromeo MD, Chang JC, Johnson JE, Repression by PRDM13 is critical for generating precision in neuronal identity. Elife. 2017 Aug 29;6:e25787 |
1 | J:137203 Mulder J, Aguado T, Keimpema E, Barabas K, Ballester Rosado CJ, Nguyen L, Monory K, Marsicano G, Di Marzo V, Hurd YL, Guillemot F, Mackie K, Lutz B, Guzman M, Lu HC, Galve-Roperh I, Harkany T, Endocannabinoid signaling controls pyramidal cell specification and long-range axon patterning. Proc Natl Acad Sci U S A. 2008 Jun 24;105(25):8760-5 |
1 | J:154587 Niquille M, Garel S, Mann F, Hornung JP, Otsmane B, Chevalley S, Parras C, Guillemot F, Gaspar P, Yanagawa Y, Lebrand C, Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C. PLoS Biol. 2009 Oct;7(10):e1000230 |
1 | J:162166 Peltopuro P, Kala K, Partanen J, Distinct requirements for Ascl1 in subpopulations of midbrain GABAergic neurons. Dev Biol. 2010 Jul 1;343(1-2):63-70 |
1 | J:313294 Raucci F, Tiong JD, Wray S, P75 nerve growth factor receptors modulate development of GnRH neurons and olfactory ensheating cells. Front Neurosci. 2013;7:262 |
1 | J:184008 Sahara S, Yanagawa Y, O'Leary DD, Stevens CF, The fraction of cortical GABAergic neurons is constant from near the start of cortical neurogenesis to adulthood. J Neurosci. 2012 Apr 4;32(14):4755-61 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:218837 Song H, Lee B, Pyun D, Guimera J, Son Y, Yoon J, Baek K, Wurst W, Jeong Y, Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation. Dev Biol. 2015 Feb 15;398(2):280-91 |
1 | J:214381 Spiegel I, Mardinly AR, Gabel HW, Bazinet JE, Couch CH, Tzeng CP, Harmin DA, Greenberg ME, Npas4 regulates excitatory-inhibitory balance within neural circuits through cell-type-specific gene programs. Cell. 2014 May 22;157(5):1216-29 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1 | J:345248 Tran HN, Nguyen QH, Jeong Y, Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron fate and regulates differentiation of the dorsal midbrain into the inferior and superior colliculi. Front Cell Dev Biol. 2024;12:1336308 |
1* | J:287411 Tran HN, Park W, Seong S, Jeong JE, Nguyen QH, Yoon J, Baek K, Jeong Y, Tcf7l2 transcription factor is required for the maintenance, but not the initial specification, of the neurotransmitter identity in the caudal thalamus. Dev Dyn. 2020 May;249(5):646-655 |
1 | J:134530 Tsunekawa N, Yanagawa Y, Obata K, Development of GABAergic neurons from the ventricular zone in the superior colliculus of the mouse. Neurosci Res. 2005 Mar;51(3):243-51 |
1 | J:197638 van den Berghe V, Stappers E, Vandesande B, Dimidschstein J, Kroes R, Francis A, Conidi A, Lesage F, Dries R, Cazzola S, Berx G, Kessaris N, Vanderhaeghen P, van Ijcken W, Grosveld FG, Goossens S, Haigh JJ, Fishell G, Goffinet A, Aerts S, Huylebroeck D, Seuntjens E, Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1. Neuron. 2013 Jan 9;77(1):70-82 |
1 | J:193303 Vidaki M, Tivodar S, Doulgeraki K, Tybulewicz V, Kessaris N, Pachnis V, Karagogeos D, Rac1-dependent cell cycle exit of MGE precursors and GABAergic interneuron migration to the cortex. Cereb Cortex. 2012 Mar;22(3):680-92 |
1 | J:159849 Wang Y, Dye CA, Sohal V, Long JE, Estrada RC, Roztocil T, Lufkin T, Deisseroth K, Baraban SC, Rubenstein JL, Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneurons. J Neurosci. 2010 Apr 14;30(15):5334-45 |
1* | J:37331 Wray S, Fueshko SM, Kusano K, Gainer H, GABAergic neurons in the embryonic olfactory pit/vomeronasal organ: maintenance of functional GABAergic synapses in olfactory explants. Dev Biol. 1996 Dec 15;180(2):631-45 |
Gad2 glutamic acid decarboxylase 2 (Synonyms: 6330404F12Rik, Gad-2, GAD(65), GAD65) | |
Results | Reference |
1 | J:50421 Alcantara S, Ruiz M, D'Arcangelo G, Ezan F, de Lecea L, Curran T , Sotelo C , Soriano E, Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse. J Neurosci. 1998 Oct 1;18(19):7779-99 |
1 | J:300487 Chai G, Webb A, Li C, Antaki D, Lee S, Breuss MW, Lang N, Stanley V, Anzenberg P, Yang X, Marshall T, Gaffney P, Wierenga KJ, Chung BH, Tsang MH, Pais LS, Lovgren AK, VanNoy GE, Rehm HL, Mirzaa G, Leon E, Diaz J, Neumann A, Kalverda AP, Manfield IW, Parry DA, Logan CV, Johnson CA, Bonthron DT, Valleley EMA, Issa MY, Abdel-Ghafar SF, Abdel-Hamid MS, Jennings P, Zaki MS, Sheridan E, Gleeson JG, Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 Jan 20;109(2):241-256.e9 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:313341 Comer JD, Pan FC, Willet SG, Haldipur P, Millen KJ, Wright CV, Kaltschmidt JA, Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3. Front Neural Circuits. 2015;9:36 |
1* | J:125023 French CA, Groszer M, Preece C, Coupe AM, Rajewsky K, Fisher SE, Generation of mice with a conditional Foxp2 null allele. Genesis. 2007 Jul;45(7):440-6 |
1 | J:336092 Knowles SJ, Stafford AM, Zaman T, Angara K, Williams MR, Newbern JM, Vogt D, Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs. Development. 2023 May 15;150(10):dev201371 |
2* | J:127151 Kwakowsky A, Schwirtlich M, Zhang Q, Eisenstat DD, Erdelyi F, Baranyi M, Katarova ZD, Szabo G, GAD isoforms exhibit distinct spatiotemporal expression patterns in the developing mouse lens: Correlation with Dlx2 and Dlx5. Dev Dyn. 2007 Dec;236(12):3532-44 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:214381 Spiegel I, Mardinly AR, Gabel HW, Bazinet JE, Couch CH, Tzeng CP, Harmin DA, Greenberg ME, Npas4 regulates excitatory-inhibitory balance within neural circuits through cell-type-specific gene programs. Cell. 2014 May 22;157(5):1216-29 |
Gadd45a growth arrest and DNA-damage-inducible 45 alpha (Synonyms: Ddit1) | |
Results | Reference |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
2* | J:191765 Sarkisian MR, Siebzehnrubl D, Abnormal levels of Gadd45alpha in developing neocortex impair neurite outgrowth. PLoS One. 2012;7(9):e44207 |
1 | J:304969 Wu F, Bard JE, Kann J, Yergeau D, Sapkota D, Ge Y, Hu Z, Wang J, Liu T, Mu X, Single cell transcriptomics reveals lineage trajectory of retinal ganglion cells in wild-type and Atoh7-null retinas. Nat Commun. 2021 Mar 5;12(1):1465 |
Gadd45g growth arrest and DNA-damage-inducible 45 gamma (Synonyms: CR6, OIG37) | |
Results | Reference |
2 | J:214032 Ishida K, Yuge Y, Hanaoka M, Yasukawa M, Minami Y, Ogawa M, Masumoto KH, Shigeyoshi Y, Saito M, Tsuji T, Gadd45g regulates dental epithelial cell proliferation through p38 MAPK-mediated p21 expression. Genes Cells. 2013 Aug;18(8):660-71 |
Gal galanin and GMAP prepropeptide (Synonyms: Galn) | |
Results | Reference |
1 | J:142008 Huang M, Huang T, Xiang Y, Xie Z, Chen Y, Yan R, Xu J, Cheng L, Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons. Dev Biol. 2008 Jul 2;322(2):394-405 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
Galns galactosamine (N-acetyl)-6-sulfatase (Synonyms: N-acetylgalactosamine-6-sulfate sulfatase) | |
Results | Reference |
1* | J:160587 Ratzka A, Mundlos S, Vortkamp A, Expression patterns of sulfatase genes in the developing mouse embryo. Dev Dyn. 2010 Jun;239(6):1779-88 |
Galnt1 polypeptide N-acetylgalactosaminyltransferase 1 (Synonyms: ppGaNTase-T1) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:74107 Kingsley PD, Hagen KG, Maltby KM, Zara J, Tabak LA, Diverse spatial expression patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyl-transferase family member mRNAs during mouse development. Glycobiology. 2000 Dec;10(12):1317-23 |
1* | J:301707 Yoshida CA, Kawane T, Moriishi T, Purushothaman A, Miyazaki T, Komori H, Mori M, Qin X, Hashimoto A, Sugahara K, Yamana K, Takada K, Komori T, Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans. J Biol Chem. 2014 Sep 19;289(38):26584-96 |
Galnt2 polypeptide N-acetylgalactosaminyltransferase 2 (Synonyms: ppGaNTase-T2) | |
Results | Reference |
1* | J:74107 Kingsley PD, Hagen KG, Maltby KM, Zara J, Tabak LA, Diverse spatial expression patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyl-transferase family member mRNAs during mouse development. Glycobiology. 2000 Dec;10(12):1317-23 |
1* | J:301707 Yoshida CA, Kawane T, Moriishi T, Purushothaman A, Miyazaki T, Komori H, Mori M, Qin X, Hashimoto A, Sugahara K, Yamana K, Takada K, Komori T, Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans. J Biol Chem. 2014 Sep 19;289(38):26584-96 |
Galnt3 polypeptide N-acetylgalactosaminyltransferase 3 (Synonyms: ppGaNTase-T3) | |
Results | Reference |
1* | J:74107 Kingsley PD, Hagen KG, Maltby KM, Zara J, Tabak LA, Diverse spatial expression patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyl-transferase family member mRNAs during mouse development. Glycobiology. 2000 Dec;10(12):1317-23 |
1* | J:301707 Yoshida CA, Kawane T, Moriishi T, Purushothaman A, Miyazaki T, Komori H, Mori M, Qin X, Hashimoto A, Sugahara K, Yamana K, Takada K, Komori T, Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans. J Biol Chem. 2014 Sep 19;289(38):26584-96 |
Galnt4 polypeptide N-acetylgalactosaminyltransferase 4 (Synonyms: ppGaNTase-T4) | |
Results | Reference |
1* | J:74107 Kingsley PD, Hagen KG, Maltby KM, Zara J, Tabak LA, Diverse spatial expression patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyl-transferase family member mRNAs during mouse development. Glycobiology. 2000 Dec;10(12):1317-23 |
1* | J:301707 Yoshida CA, Kawane T, Moriishi T, Purushothaman A, Miyazaki T, Komori H, Mori M, Qin X, Hashimoto A, Sugahara K, Yamana K, Takada K, Komori T, Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans. J Biol Chem. 2014 Sep 19;289(38):26584-96 |
Galnt5 polypeptide N-acetylgalactosaminyltransferase 5 (Synonyms: ppGaNTase-T5) | |
Results | Reference |
1* | J:74107 Kingsley PD, Hagen KG, Maltby KM, Zara J, Tabak LA, Diverse spatial expression patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyl-transferase family member mRNAs during mouse development. Glycobiology. 2000 Dec;10(12):1317-23 |
1* | J:301707 Yoshida CA, Kawane T, Moriishi T, Purushothaman A, Miyazaki T, Komori H, Mori M, Qin X, Hashimoto A, Sugahara K, Yamana K, Takada K, Komori T, Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans. J Biol Chem. 2014 Sep 19;289(38):26584-96 |
Galnt6 polypeptide N-acetylgalactosaminyltransferase 6 (Synonyms: GalNAc-T6) | |
Results | Reference |
1* | J:301707 Yoshida CA, Kawane T, Moriishi T, Purushothaman A, Miyazaki T, Komori H, Mori M, Qin X, Hashimoto A, Sugahara K, Yamana K, Takada K, Komori T, Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans. J Biol Chem. 2014 Sep 19;289(38):26584-96 |
Galnt7 polypeptide N-acetylgalactosaminyltransferase 7 (Synonyms: ppGaNTase-T7) | |
Results | Reference |
1* | J:74107 Kingsley PD, Hagen KG, Maltby KM, Zara J, Tabak LA, Diverse spatial expression patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyl-transferase family member mRNAs during mouse development. Glycobiology. 2000 Dec;10(12):1317-23 |
1* | J:301707 Yoshida CA, Kawane T, Moriishi T, Purushothaman A, Miyazaki T, Komori H, Mori M, Qin X, Hashimoto A, Sugahara K, Yamana K, Takada K, Komori T, Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans. J Biol Chem. 2014 Sep 19;289(38):26584-96 |
Galnt10 polypeptide N-acetylgalactosaminyltransferase 10 (Synonyms: C330012K04Rik, GalNAc-T10, Galnt9) | |
Results | Reference |
1* | J:74107 Kingsley PD, Hagen KG, Maltby KM, Zara J, Tabak LA, Diverse spatial expression patterns of UDP-GalNAc:polypeptide N-acetylgalactosaminyl-transferase family member mRNAs during mouse development. Glycobiology. 2000 Dec;10(12):1317-23 |
1* | J:301707 Yoshida CA, Kawane T, Moriishi T, Purushothaman A, Miyazaki T, Komori H, Mori M, Qin X, Hashimoto A, Sugahara K, Yamana K, Takada K, Komori T, Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans. J Biol Chem. 2014 Sep 19;289(38):26584-96 |
Galnt11 polypeptide N-acetylgalactosaminyltransferase 11 (Synonyms: A430075I06Rik, E430002F06Rik) | |
Results | Reference |
1* | J:301707 Yoshida CA, Kawane T, Moriishi T, Purushothaman A, Miyazaki T, Komori H, Mori M, Qin X, Hashimoto A, Sugahara K, Yamana K, Takada K, Komori T, Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans. J Biol Chem. 2014 Sep 19;289(38):26584-96 |
Galnt12 polypeptide N-acetylgalactosaminyltransferase 12 (Synonyms: A630062B03Rik) | |
Results | Reference |
1* | J:301707 Yoshida CA, Kawane T, Moriishi T, Purushothaman A, Miyazaki T, Komori H, Mori M, Qin X, Hashimoto A, Sugahara K, Yamana K, Takada K, Komori T, Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans. J Biol Chem. 2014 Sep 19;289(38):26584-96 |
Galnt13 polypeptide N-acetylgalactosaminyltransferase 13 (Synonyms: pp-GalNAc-T13) | |
Results | Reference |
1* | J:301707 Yoshida CA, Kawane T, Moriishi T, Purushothaman A, Miyazaki T, Komori H, Mori M, Qin X, Hashimoto A, Sugahara K, Yamana K, Takada K, Komori T, Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans. J Biol Chem. 2014 Sep 19;289(38):26584-96 |
Galnt14 polypeptide N-acetylgalactosaminyltransferase 14 (Synonyms: 0610033M06Rik) | |
Results | Reference |
1* | J:301707 Yoshida CA, Kawane T, Moriishi T, Purushothaman A, Miyazaki T, Komori H, Mori M, Qin X, Hashimoto A, Sugahara K, Yamana K, Takada K, Komori T, Overexpression of Galnt3 in chondrocytes resulted in dwarfism due to the increase of mucin-type O-glycans and reduction of glycosaminoglycans. J Biol Chem. 2014 Sep 19;289(38):26584-96 |
Galr1 galanin receptor 1 (Synonyms: Galnr1) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Galr2 galanin receptor 2 (Synonyms: GalR2, mGalR) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Galr3 galanin receptor 3 (Synonyms: Galnr3) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Ganab alpha glucosidase 2 alpha neutral subunit (Synonyms: G2an, GluII, mKIAA0088) | |
Results | Reference |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
Gap43 growth associated protein 43 (Synonyms: B-50, Basp2, GAP-43, neuromodulin) | |
Results | Reference |
1 | J:84095 Bao J, Wolpowitz D, Role LW, Talmage DA, Back signaling by the Nrg-1 intracellular domain. J Cell Biol. 2003 Jun 23;161(6):1133-41 |
1 | J:137425 Blanchart A, Romaguera M, Garcia-Verdugo JM, de Carlos JA, Lopez-Mascaraque L, Synaptogenesis in the mouse olfactory bulb during glomerulus development. Eur J Neurosci. 2008 Jun;27(11):2838-46 |
1 | J:337815 Bunt J, Osinski JM, Lim JW, Vidovic D, Ye Y, Zalucki O, O'Connor TR, Harris L, Gronostajski RM, Richards LJ, Piper M, Combined allelic dosage of Nfia and Nfib regulates cortical development. Brain Neurosci Adv. 2017 Jan-Dec;1:2398212817739433 |
1 | J:240770 Gobius I, Morcom L, Suarez R, Bunt J, Bukshpun P, Reardon W, Dobyns WB, Rubenstein JL, Barkovich AJ, Sherr EH, Richards LJ, Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum. Cell Rep. 2016 Oct 11;17(3):735-747 |
1* | J:243644 Gobius I, Suarez R, Morcom L, Paolino A, Edwards TJ, Kozulin P, Richards LJ, Astroglial-mediated remodeling of the interhemispheric midline during telencephalic development is exclusive to eutherian mammals. Neural Dev. 2017 May 30;12(1):9 |
1* | J:263979 Harley RJ, Murdy JP, Wang Z, Kelly MC, Ropp TF, Park SH, Maness PF, Manis PB, Coate TM, Neuronal cell adhesion molecule (NrCAM) is expressed by sensory cells in the cochlea and is necessary for proper cochlear innervation and sensory domain patterning during development. Dev Dyn. 2018 Mar 14; |
1 | J:126807 Hippenmeyer S, Huber RM, Ladle DR, Murphy K, Arber S, ETS transcription factor Erm controls subsynaptic gene expression in skeletal muscles. Neuron. 2007 Sep 6;55(5):726-40 |
1* | J:91247 Hirata T, Suda Y, Nakao K, Narimatsu M, Hirano T, Hibi M, Zinc finger gene fez-like functions in the formation of subplate neurons and thalamocortical axons. Dev Dyn. 2004 Jul;230(3):546-56 |
2* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
1* | J:91307 Korteweg N, Maia AS, Verhage M, Burbach JP, Development of the mouse hypothalamo-neurohypophysial system in the munc18-1 null mutant that lacks regulated secretion. Eur J Neurosci. 2004 Jun;19(11):2944-52 |
1 | J:104532 Mendes SW, Henkemeyer M, Liebl DJ, Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J Neurosci. 2006 Jan 18;26(3):882-92 |
1 | J:196051 Moldrich RX, Gobius I, Pollak T, Zhang J, Ren T, Brown L, Mori S, De Juan Romero C, Britanova O, Tarabykin V, Richards LJ, Molecular regulation of the developing commissural plate. J Comp Neurol. 2010 Sep 15;518(18):3645-61 |
1* | J:76364 Pun S, Sigrist M, Santos AF, Ruegg MA, Sanes JR, Jessell TM, Arber S, Caroni P, An intrinsic distinction in neuromuscular junction assembly and maintenance in different skeletal muscles. Neuron. 2002 Apr 25;34(3):357-70 |
1* | J:77124 Shinozaki K, Miyagi T, Yoshida M, Miyata T, Ogawa M, Aizawa S, Suda Y, Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double mutant cerebral cortex. Development. 2002 Jul;129(14):3479-92 |
1 | J:110263 Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM, Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat Neurosci. 2006 Jun;9(6):787-97 |
1 | J:167943 Takeuchi H, Inokuchi K, Aoki M, Suto F, Tsuboi A, Matsuda I, Suzuki M, Aiba A, Serizawa S, Yoshihara Y, Fujisawa H, Sakano H, Sequential arrival and graded secretion of Sema3F by olfactory neuron axons specify map topography at the bulb. Cell. 2010 Jun 11;141(6):1056-67 |
1 | J:73913 Tisay KT, St John JA, Key B, Expression of specific glycoconjugates in both primary and secondary olfactory pathways in BALB/C mice. J Comp Neurol. 2002 Feb 11;443(3):213-25 |
1* | J:104160 Tole S, Gutin G, Bhatnagar L, Remedios R, Hebert JM, Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev Biol. 2006 Jan 1;289(1):141-51 |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
1* | J:184936 Unni DK, Piper M, Moldrich RX, Gobius I, Liu S, Fothergill T, Donahoo AL, Baisden JM, Cooper HM, Richards LJ, Multiple Slits regulate the development of midline glial populations and the corpus callosum. Dev Biol. 2012 May 1;365(1):36-49 |
1 | J:164874 Wang L, Vervoort V, Wallez Y, Core N, Cremer H, Pasquale EB, The SRC homology 2 domain protein Shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain. J Neurosci. 2010 Sep 29;30(39):13201-10 |
1 | J:302429 Wang Z, Jung JS, Inbar TC, Rangoussis KM, Faaborg-Andersen C, Coate TM, The Purinergic Receptor P2rx3 is Required for Spiral Ganglion Neuron Branch Refinement during Development. eNeuro. 2020 Jul/Aug;7(4):ENEURO.0179-20.2020 |
1 | J:174482 Watanabe Y, Inoue K, Okuyama-Yamamoto A, Nakai N, Nakatani J, Nibu K, Sato N, Iiboshi Y, Yusa K, Kondoh G, Takeda J, Terashima T, Takumi T, Fezf1 is required for penetration of the basal lamina by olfactory axons to promote olfactory development. J Comp Neurol. 2009 Aug 10;515(5):565-84 |
1 | J:308798 Wittmann MT, Katada S, Sock E, Kirchner P, Ekici AB, Wegner M, Nakashima K, Lie DC, Reis A, scRNA sequencing uncovers a TCF4-dependent transcription factor network regulating commissure development in mouse. Development. 2021 Jul 15;148(14):dev196022 |
Gapdh glyceraldehyde-3-phosphate dehydrogenase (Synonyms: Gapd) | |
Results | Reference |
1 | J:119559 Bouwman J, Spijker S, Schut D, Wachtler B, Ylstra B, Smit AB, Verhage M, Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse. J Neurochem. 2006 Oct;99(1):84-96 |
1* | J:134647 Honda JY, Kobayashi I, Kiyoshima T, Yamaza H, Xie M, Takahashi K, Enoki N, Nagata K, Nakashima A, Sakai H, Glycolytic enzyme Pgk1 is strongly expressed in the developing tooth germ of the mouse lower first molar. Histol Histopathol. 2008 Apr;23(4):423-32 |
1 | J:190424 Kraemer N, Neubert G, Issa L, Ninnemann O, Seiler AE, Kaindl AM, Reference genes in the developing murine brain and in differentiating embryonic stem cells. Neurol Res. 2012 Sep;34(7):664-8 |
2 | J:330439 Liu H, He L, Cheng Q, Luo W, Zhao T, Yang D, Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states. Int J Mol Med. 2022 Nov;50(5) |
1 | J:316972 Mehta A, Dobersch S, Dammann RH, Bellusci S, Ilinskaya ON, Braun T, Barreto G, Validation of Tuba1a as appropriate internal control for normalization of gene expression analysis during mouse lung development. Int J Mol Sci. 2015 Feb 25;16(3):4492-511 |
1 | J:317613 Patnaik SR, Kretschmer V, Brucker L, Schneider S, Volz AK, Oancea-Castillo LDR, May-Simera HL, Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation. Cell Mol Life Sci. 2019 Feb;76(4):757-775 |
1* | J:160194 Shaw L, Johnson PA, Kimber SJ, Gene expression profiling of the developing mouse kidney and embryo. In Vitro Cell Dev Biol Anim. 2010 Feb;46(2):155-65 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Gas1 growth arrest specific 1 (Synonyms: Gas-1) | |
Results | Reference |
2 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1 | J:346064 Leung AOW, Poon ACH, Wang X, Feng C, Chen P, Zheng Z, To MK, Chan WCW, Cheung M, Chan D, Suppression of apoptosis impairs phalangeal joint formation in the pathogenesis of brachydactyly type A1. Nat Commun. 2024 Mar 12;15(1):2229 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Gas2 growth arrest specific 2 (Synonyms: Gas-2) | |
Results | Reference |
1 | J:306028 Chen T, Rohacek AM, Caporizzo M, Nankali A, Smits JJ, Oostrik J, Lanting CP, Kucuk E, Gilissen C, van de Kamp JM, Pennings RJE, Rakowiecki SM, Kaestner KH, Ohlemiller KK, Oghalai JS, Kremer H, Prosser BL, Epstein DJ, Cochlear supporting cells require GAS2 for cytoskeletal architecture and hearing. Dev Cell. 2021 May 17;56(10):1526-1540.e7 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1 | J:251841 York JP, Ren YA, Zeng J, Bin Zhang, Wang F, Chen R, Liu J, Xia X, Zhang P, Growth Arrest Specific 2 (GAS2) is a Critical Mediator of Germ Cell Cyst Breakdown and Folliculogenesis in Mice. Sci Rep. 2016 Oct 13;6:34956 |
Gas2l3 growth arrest-specific 2 like 3 (Synonyms: 8430435B07Rik, LOC237436) | |
Results | Reference |
1* | J:244087 Stopp S, Grundl M, Fackler M, Malkmus J, Leone M, Naumann R, Frantz S, Wolf E, von Eyss B, Engel FB, Gaubatz S, Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during development. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):8029-8034 |
Gas6 growth arrest specific 6 (Synonyms: Gas-6, GAS 6, growth arrest-specific) | |
Results | Reference |
1 | J:356085 Wang J, Tian GG, Zheng Z, Li B, Xing Q, Wu J, Comprehensive Transcriptomic Analysis of Mouse Gonadal Development Involving Sexual Differentiation, Meiosis and Gametogenesis. Biol Proced Online. 2019;21:20 |
Gas8 growth arrest specific 8 (Synonyms: Gas11) | |
Results | Reference |
2 | J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6 |
Gast gastrin (Synonyms: GAS) | |
Results | Reference |
1 | J:119565 Boyer DF, Fujitani Y, Gannon M, Powers AC, Stein RW, Wright CV, Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression. Dev Biol. 2006 Oct 15;298(2):616-31 |
1 | J:272578 Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G, Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. Dev Cell. 2019 Jan 7;48(1):49-63.e7 |
1 | J:101154 Stanger BZ, Datar R, Murtaugh LC, Melton DA, Direct regulation of intestinal fate by Notch. Proc Natl Acad Sci U S A. 2005 Aug 30;102(35):12443-8 |
Gata1 GATA binding protein 1 (Synonyms: Gata-1, Gf-1) | |
Results | Reference |
1 | J:119284 Decker K, Goldman DC, Grasch CL, Sussel L, Gata6 is an important regulator of mouse pancreas development. Dev Biol. 2006 Oct 15;298(2):415-29 |
1* | J:271614 Gudmundsdottir B, Gudmundsson KO, Klarmann KD, Singh SK, Sun L, Singh S, Du Y, Coppola V, Stockwin L, Nguyen N, Tessarollo L, Thorsteinsson L, Sigurjonsson OE, Gudmundsson S, Rafnar T, Tisdale JF, Keller JR, POGZ Is Required for Silencing Mouse Embryonic beta-like Hemoglobin and Human Fetal Hemoglobin Expression. Cell Rep. 2018 Jun 12;23(11):3236-3248 |
1* | J:31166 Jippo T, Mizuno H, Xu Z, Nomura S, Yamamoto M, Kitamura Y, Abundant expression of transcription factor GATA-2 in proliferating but not in differentiated mast cells in tissues of mice: demonstration by in situ hybridization. Blood. 1996 Feb 1;87(3):993-8 |
1* | J:358134 Soma S, Murakami K, Fukuchi Y, Kunimoto H, Nakajima H, O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. Stem Cells. 2024 Jan 13;42(1):55-63 |
1* | J:285404 Ueda T, Yokota T, Okuzaki D, Uno Y, Mashimo T, Kubota Y, Sudo T, Ishibashi T, Shingai Y, Doi Y, Ozawa T, Nakai R, Tanimura A, Ichii M, Ezoe S, Shibayama H, Oritani K, Kanakura Y, Endothelial Cell-Selective Adhesion Molecule Contributes to the Development of Definitive Hematopoiesis in the Fetal Liver. Stem Cell Reports. 2019 Dec 10;13(6):992-1005 |
Gata2 GATA binding protein 2 (Synonyms: Gata-2) | |
Results | Reference |
1 | J:309359 Brinkmeier ML, Bando H, Camarano AC, Fujio S, Yoshimoto K, de Souza FS, Camper SA, Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. J Clin Invest. 2020 Aug 3;130(8):4501-4515 |
1 | J:70561 Dasen JS, O'Connell SM, Flynn SE, Treier M, Gleiberman AS, Szeto DP, Hooshmand F, Aggarwal AK, Rosenfeld MG, Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types. Cell. 1999 May 28;97(5):587-98 |
1 | J:119284 Decker K, Goldman DC, Grasch CL, Sussel L, Gata6 is an important regulator of mouse pancreas development. Dev Biol. 2006 Oct 15;298(2):415-29 |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
1 | J:228882 Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS, Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016 Jan 1;409(1):218-33 |
1* | J:163272 Haugas M, Lillevali K, Hakanen J, Salminen M, Gata2 is required for the development of inner ear semicircular ducts and the surrounding perilymphatic space. Dev Dyn. 2010 Sep;239(9):2452-69 |
1 | J:237535 Haugas M, Tikker L, Achim K, Salminen M, Partanen J, Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe. Development. 2016 Dec 01;143(23):4495-4508 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
2* | J:31166 Jippo T, Mizuno H, Xu Z, Nomura S, Yamamoto M, Kitamura Y, Abundant expression of transcription factor GATA-2 in proliferating but not in differentiated mast cells in tissues of mice: demonstration by in situ hybridization. Blood. 1996 Feb 1;87(3):993-8 |
1 | J:335167 Lu P, Wu B, Wang Y, Russell M, Liu Y, Bernard DJ, Zheng D, Zhou B, Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis. Dev Cell. 2023 Mar 29; |
1* | J:55464 Rivolta MN, Holley MC, GATA3 is downregulated during hair cell differentiation in the mouse cochlea. J Neurocytol. 1998 Sep;27(9):637-47 |
1 | J:357469 Sivori M, Dempsey B, Chettouh Z, Boismoreau F, Ayerdi M, et al., The pelvic organs receive no parasympathetic innervation. Elife. 2024;15 |
1 | J:342641 Tenney AP, Di Gioia SA, Webb BD, Chan WM, de Boer E, Garnai SJ, Barry BJ, Ray T, Kosicki M, Robson CD, Zhang Z, Collins TE, Gelber A, Pratt BM, Fujiwara Y, Varshney A, Lek M, Warburton PE, Van Ryzin C, Lehky TJ, Zalewski C, King KA, Brewer CC, Thurm A, Snow J, Facio FM, Narisu N, Bonnycastle LL, Swift A, Chines PS, Bell JL, Mohan S, Whitman MC, Staffieri SE, Elder JE, Demer JL, Torres A, Rachid E, Al-Haddad C, Boustany RM, Mackey DA, Brady AF, Fenollar-Cortes M, Fradin M, Kleefstra T, Padberg GW, Raskin S, Sato MT, Orkin SH, Parker SCJ, Hadlock TA, Vissers LELM, van Bokhoven H, Jabs EW, Collins FS, Pennacchio LA, Manoli I, Engle EC, Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis. Nat Genet. 2023 Jul;55(7):1149-1163 |
1 | J:297686 Watanabe-Asaka T, Hayashi M, Engel JD, Kawai Y, Moriguchi T, GATA2 functions in adrenal chromaffin cells. Genes Cells. 2020 Sep;25(9):607-614 |
3* | J:279388 Weiss AC, Bohnenpoll T, Kurz J, Blank P, Airik R, Ludtke TH, Kleppa MJ, Deuper L, Kaiser M, Mamo TM, Costa R, von Hahn T, Trowe MO, Kispert A, Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme. J Pathol. 2019 Aug;248(4):452-463 |
Gata3 GATA binding protein 3 (Synonyms: Gata-3, jal) | |
Results | Reference |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1 | J:166770 Coppola E, d'Autreaux F, Rijli FM, Brunet JF, Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation. Development. 2010 Dec;137(24):4211-20 |
1 | J:119006 de Guzman Strong C, Wertz PW, Wang C, Yang F, Meltzer PS, Andl T, Millar SE, Ho IC, Pai SY, Segre JA, Lipid defect underlies selective skin barrier impairment of an epidermal-specific deletion of Gata-3. J Cell Biol. 2006 Nov 20;175(4):661-70 |
1 | J:119284 Decker K, Goldman DC, Grasch CL, Sussel L, Gata6 is an important regulator of mouse pancreas development. Dev Biol. 2006 Oct 15;298(2):415-29 |
1 | J:237201 Espinosa-Medina I, Saha O, Boismoreau F, Chettouh Z, Rossi F, Richardson WD, Brunet JF, The sacral autonomic outflow is sympathetic. Science. 2016 Nov 18;354(6314):893-897 |
1 | J:237535 Haugas M, Tikker L, Achim K, Salminen M, Partanen J, Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe. Development. 2016 Dec 01;143(23):4495-4508 |
1 | J:332402 Hockman D, Adameyko I, Kaucka M, Barraud P, Otani T, Hunt A, Hartwig AC, Sock E, Waithe D, Franck MCM, Ernfors P, Ehinger S, Howard MJ, Brown N, Reese J, Baker CVH, Striking parallels between carotid body glomus cell and adrenal chromaffin cell development. Dev Biol. 2018 Dec 1;444 Suppl 1(Suppl 1):S308-S324 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:152264 Koo SK, Hill JK, Hwang CH, Lin ZS, Millen KJ, Wu DK, Lmx1a maintains proper neurogenic, sensory, and non-sensory domains in the mammalian inner ear. Dev Biol. 2009 Sep 1;333(1):14-25 |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
1* | J:114661 Lyu YL, Lin CP, Azarova AM, Cai L, Wang JC, Liu LF, Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Mol Cell Biol. 2006 Nov;26(21):7929-41 |
3 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
1* | J:266904 Martynova E, Bouchard M, Musil LS, Cvekl A, Identification of Novel Gata3 Distal Enhancers Active in Mouse Embryonic Lens. Dev Dyn. 2018 Nov;247(11):1186-1198 |
2 | J:221833 Prakash A, Udager AM, Saenz DA, Gumucio DL, Roles for Nkx2-5 and Gata3 in the ontogeny of the murine smooth muscle gastric ligaments. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 15;307(4):G430-6 |
1* | J:55464 Rivolta MN, Holley MC, GATA3 is downregulated during hair cell differentiation in the mouse cochlea. J Neurocytol. 1998 Sep;27(9):637-47 |
1 | J:173638 Schmidt M, Huber L, Majdazari A, Schutz G, Williams T, Rohrer H, The transcription factors AP-2beta and AP-2alpha are required for survival of sympathetic progenitors and differentiated sympathetic neurons. Dev Biol. 2011 Jul 1;355(1):89-100 |
1 | J:287023 Schnerwitzki D, Perry S, Ivanova A, Caixeta FV, Cramer P, Gunther S, Weber K, Tafreshiha A, Becker L, Vargas Panesso IL, Klopstock T, Hrabe de Angelis M, Schmidt M, Kullander K, Englert C, Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord. Life Sci Alliance. 2018 Aug;1(4):e201800106 |
1 | J:357469 Sivori M, Dempsey B, Chettouh Z, Boismoreau F, Ayerdi M, et al., The pelvic organs receive no parasympathetic innervation. Elife. 2024;15 |
1 | J:218837 Song H, Lee B, Pyun D, Guimera J, Son Y, Yoon J, Baek K, Wurst W, Jeong Y, Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation. Dev Biol. 2015 Feb 15;398(2):280-91 |
1 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
1 | J:338930 Tarnick J, Elhendawi M, Holland I, Chang Z, Davies JA, Innervation of the developing kidney in vivo and in vitro. Biol Open. 2023 Aug 15;12(8) |
1 | J:342641 Tenney AP, Di Gioia SA, Webb BD, Chan WM, de Boer E, Garnai SJ, Barry BJ, Ray T, Kosicki M, Robson CD, Zhang Z, Collins TE, Gelber A, Pratt BM, Fujiwara Y, Varshney A, Lek M, Warburton PE, Van Ryzin C, Lehky TJ, Zalewski C, King KA, Brewer CC, Thurm A, Snow J, Facio FM, Narisu N, Bonnycastle LL, Swift A, Chines PS, Bell JL, Mohan S, Whitman MC, Staffieri SE, Elder JE, Demer JL, Torres A, Rachid E, Al-Haddad C, Boustany RM, Mackey DA, Brady AF, Fenollar-Cortes M, Fradin M, Kleefstra T, Padberg GW, Raskin S, Sato MT, Orkin SH, Parker SCJ, Hadlock TA, Vissers LELM, van Bokhoven H, Jabs EW, Collins FS, Pennacchio LA, Manoli I, Engle EC, Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis. Nat Genet. 2023 Jul;55(7):1149-1163 |
1* | J:287411 Tran HN, Park W, Seong S, Jeong JE, Nguyen QH, Yoon J, Baek K, Jeong Y, Tcf7l2 transcription factor is required for the maintenance, but not the initial specification, of the neurotransmitter identity in the caudal thalamus. Dev Dyn. 2020 May;249(5):646-655 |
1 | J:228275 Udager AM, Prakash A, Saenz DA, Schinke M, Moriguchi T, Jay PY, Lim KC, Engel JD, Gumucio DL, Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3. Gastroenterology. 2014 Jan;146(1):157-65.e10 |
1 | J:297686 Watanabe-Asaka T, Hayashi M, Engel JD, Kawai Y, Moriguchi T, GATA2 functions in adrenal chromaffin cells. Genes Cells. 2020 Sep;25(9):607-614 |
1 | J:207904 Yu WM, Appler JM, Kim YH, Nishitani AM, Holt JR, Goodrich LV, A Gata3-Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearing. Elife. 2013;2:e01341 |
Gata3un Gata3 upstream neighbor (Synonyms: 9230102O04Rik, linc_Gata3) | |
Results | Reference |
1* | J:258363 Ushakov K, Koffler-Brill T, Rom A, Perl K, Ulitsky I, Avraham KB, Genome-wide identification and expression profiling of long non-coding RNAs in auditory and vestibular systems. Sci Rep. 2017 Aug 17;7(1):8637 |
Gata4 GATA binding protein 4 (Synonyms: Gata-4) | |
Results | Reference |
1 | J:153920 Agnihotri S, Wolf A, Picard D, Hawkins C, Guha A, GATA4 is a regulator of astrocyte cell proliferation and apoptosis in the human and murine central nervous system. Oncogene. 2009 Aug 27;28(34):3033-46 |
2 | J:122635 Bosse T, Fialkovich JJ, Piaseckyj CM, Beuling E, Broekman H, Grand RJ, Montgomery RK, Krasinski SD, Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development. Am J Physiol Gastrointest Liver Physiol. 2007 May;292(5):G1302-14 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
2 | J:119284 Decker K, Goldman DC, Grasch CL, Sussel L, Gata6 is an important regulator of mouse pancreas development. Dev Biol. 2006 Oct 15;298(2):415-29 |
1 | J:313347 DeLaForest A, Kohlnhofer BM, Franklin OD, Stavniichuk R, Thompson CA, Pulakanti K, Rao S, Battle MA, GATA4 Controls Epithelial Morphogenesis in the Developing Stomach to Promote Establishment of Glandular Columnar Epithelium. Cell Mol Gastroenterol Hepatol. 2021;12(4):1391-1413 |
1 | J:234748 Guemes M, Garcia AJ, Rigueur D, Runke S, Wang W, Zhao G, Mayorga VH, Atti E, Tetradis S, Peault B, Lyons K, Miranda-Carboni GA, Krum SA, GATA4 is essential for bone mineralization via ERalpha and TGFbeta/BMP pathways. J Bone Miner Res. 2014 Dec;29(12):2676-87 |
1* | J:231673 Gustin SE, Hogg K, Stringer JM, Rastetter RH, Pelosi E, Miles DC, Sinclair AH, Wilhelm D, Western PS, WNT/beta-catenin and p27/FOXL2 differentially regulate supporting cell proliferation in the developing ovary. Dev Biol. 2016 Apr 15;412(2):250-60 |
2 | J:224301 Harris JP, Bhakta M, Bezprozvannaya S, Wang L, Lubczyk C, Olson EN, Munshi NV, MyoR modulates cardiac conduction by repressing Gata4. Mol Cell Biol. 2015 Feb;35(4):649-61 |
2* | J:179371 He A, Shen X, Ma Q, Cao J, von Gise A, Zhou P, Wang G, Marquez VE, Orkin SH, Pu WT, PRC2 directly methylates GATA4 and represses its transcriptional activity. Genes Dev. 2012 Jan 1;26(1):37-42 |
1* | J:92209 Huang F, Wagner M, Siddiqui MA, Ablation of the CLP-1 gene leads to down-regulation of the HAND1 gene and abnormality of the left ventricle of the heart and fetal death. Mech Dev. 2004 Jun;121(6):559-72 |
1 | J:183651 Kim EY, Chen L, Ma Y, Yu W, Chang J, Moskowitz IP, Wang J, Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J Mol Cell Cardiol. 2012 Mar;52(3):638-49 |
1* | J:347585 Leon NY, Le TNU, Garvie A, Wong LH, Bagheri-Fam S, Harley VR, Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. iScience. 2024 May 17;27(5):109629 |
1 | J:246806 Li Y, Zhang L, Hu Y, Chen M, Han F, Qin Y, Chen M, Cui X, Duo S, Tang F, Gao F, beta-Catenin directs the transformation of testis Sertoli cells to ovarian granulosa-like cells by inducing Foxl2 expression. J Biol Chem. 2017 Oct 27;292(43):17577-17586 |
1 | J:338955 Maezawa S, Yukawa M, Hasegawa K, Sugiyama R, Iizuka M, Hu M, Sakashita A, Vidal M, Koseki H, Barski A, DeFalco T, Namekawa SH, PRC1 suppresses a female gene regulatory network to ensure testicular differentiation. Cell Death Dis. 2023 Aug 4;14(8):501 |
1* | J:173838 Manuylov NL, Zhou B, Ma Q, Fox SC, Pu WT, Tevosian SG, Conditional ablation of Gata4 and Fog2 genes in mice reveals their distinct roles in mammalian sexual differentiation. Dev Biol. 2011 May 15;353(2):229-41 |
1 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1 | J:158526 Naillat F, Prunskaite-Hyyrylainen R, Pietila I, Sormunen R, Jokela T, Shan J, Vainio SJ, Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development. Hum Mol Genet. 2010 Apr 15;19(8):1539-50 |
2 | J:171273 Nakajima K, Inagawa M, Uchida C, Okada K, Tane S, Kojima M, Kubota M, Noda M, Ogawa S, Shirato H, Sato M, Suzuki-Migishima R, Hino T, Satoh Y, Kitagawa M, Takeuchi T, Coordinated regulation of differentiation and proliferation of embryonic cardiomyocytes by a jumonji (Jarid2)-cyclin D1 pathway. Development. 2011 May;138(9):1771-82 |
1* | J:231047 Rios-Rojas C, Spiller C, Bowles J, Koopman P, Germ cells influence cord formation and leydig cell gene expression during mouse testis development. Dev Dyn. 2016 Apr;245(4):433-44 |
1 | J:301269 Sankoda N, Tanabe W, Tanaka A, Shibata H, Woltjen K, Chiba T, Haga H, Sakai Y, Mandai M, Yamamoto T, Yamada Y, Uemoto S, Kawaguchi Y, Epithelial expression of Gata4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice. Nat Commun. 2021 Jan 25;12(1):560 |
1 | J:98520 Takamoto N, You LR, Moses K, Chiang C, Zimmer WE, Schwartz RJ, Demayo FJ, Tsai MJ, Tsai SY, COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development. 2005 May;132(9):2179-89 |
3* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
1 | J:332220 Uchida A, Imaimatsu K, Suzuki H, Han X, Ushioda H, Uemura M, Imura-Kishi K, Hiramatsu R, Takase HM, Hirate Y, Ogura A, Kanai-Azuma M, Kudo A, Kanai Y, SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse. Nat Commun. 2022 Dec 21;13(1):7860 |
1* | J:49151 Viger RS, Mertineit C, Trasler JM, Nemer M, Transcription factor GATA-4 is expressed in a sexually dimorphic pattern during mouse gonadal development and is a potent activator of the Mullerian inhibiting substance promoter. Development. 1998 Jul;125(14):2665-75 |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
1 | J:187416 Wat MJ, Beck TF, Hernandez-Garcia A, Yu Z, Veenma D, Garcia M, Holder AM, Wat JJ, Chen Y, Mohila CA, Lally KP, Dickinson M, Tibboel D, de Klein A, Lee B, Scott DA, Mouse model reveals the role of SOX7 in the development of congenital diaphragmatic hernia associated with recurrent deletions of 8p23.1. Hum Mol Genet. 2012 Sep 15;21(18):4115-25 |
Gata5 GATA binding protein 5 | |
Results | Reference |
1 | J:119284 Decker K, Goldman DC, Grasch CL, Sussel L, Gata6 is an important regulator of mouse pancreas development. Dev Biol. 2006 Oct 15;298(2):415-29 |
1* | J:38927 Morrisey EE, Ip HS, Tang Z, Lu MM, Parmacek MS, GATA-5: a transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development. Dev Biol. 1997 Mar 1;183(1):21-36 |
Gata6 GATA binding protein 6 | |
Results | Reference |
1* | J:59167 Brewer A, Gove C, Davies A, McNulty C, Barrow D, Koutsourakis M, Farzaneh F, Pizzey J, Bomford A, Patient R, The human and mouse GATA-6 genes utilize two promoters and two initiation codons. J Biol Chem. 1999 Dec 31;274(53):38004-16 |
1* | J:81314 Brewer A, Nemer G, Gove C, Rawlins F, Nemer M, Patient R, Pizzey J, Widespread expression of an extended peptide sequence of GATA-6 during murine embryogenesis and non-equivalence of RNA and protein expression domains. Mech Dev. 2002 Dec;119 Suppl 1:S121-9 |
1 | J:119284 Decker K, Goldman DC, Grasch CL, Sussel L, Gata6 is an important regulator of mouse pancreas development. Dev Biol. 2006 Oct 15;298(2):415-29 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1* | J:212084 Herriges MJ, Swarr DT, Morley MP, Rathi KS, Peng T, Stewart KM, Morrisey EE, Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development. Genes Dev. 2014 Jun 15;28(12):1363-79 |
1 | J:342314 Jun S, Angueira AR, Fein EC, Tan JME, Weller AH, Cheng L, Batmanov K, Ishibashi J, Sakers AP, Stine RR, Seale P, Control of murine brown adipocyte development by GATA6. Dev Cell. 2023 Nov 6;58(21):2195-2205.e5 |
3 | J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522 |
1 | J:111670 Kyrmizi I, Hatzis P, Katrakili N, Tronche F, Gonzalez FJ, Talianidis I, Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev. 2006 Aug 15;20(16):2293-305 |
1 | J:317604 Liu F, Lu MM, Patel NN, Schillinger KJ, Wang T, Patel VV, GATA-Binding Factor 6 Contributes to Atrioventricular Node Development and Function. Circ Cardiovasc Genet. 2015 Apr;8(2):284-93 |
2 | J:191793 Schnatwinkel C, Niswander L, Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice. PLoS One. 2012;7(9):e44871 |
1 | J:121421 Shu W, Lu MM, Zhang Y, Tucker PW, Zhou D, Morrisey EE, Foxp2 and Foxp1 cooperatively regulate lung and esophagus development. Development. 2007 May;134(10):1991-2000 |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
2 | J:117072 Zhang Y, Rath N, Hannenhalli S, Wang Z, Cappola T, Kimura S, Atochina-Vasserman E, Lu MM, Beers MF, Morrisey EE, GATA and Nkx factors synergistically regulate tissue-specific gene expression and development in vivo. Development. 2007 Jan;134(1):189-98 |
Gata6os GATA binding protein 6, opposite strand (Synonyms: 1010001N08Rik, Gata6as, LncGata6) | |
Results | Reference |
1* | J:212084 Herriges MJ, Swarr DT, Morley MP, Rathi KS, Peng T, Stewart KM, Morrisey EE, Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development. Genes Dev. 2014 Jun 15;28(12):1363-79 |
Gatad2b GATA zinc finger domain containing 2B (Synonyms: C430014D17Rik, p66beta) | |
Results | Reference |
1 | J:344365 Abad C, Robayo MC, Muniz-Moreno MDM, Bernardi MT, Otero MG, Kosanovic C, Griswold AJ, Pierson TM, Walz K, Young JI, Gatad2b, associated with the neurodevelopmental syndrome GAND, plays a critical role in neurodevelopment and cortical patterning. Transl Psychiatry. 2024 Jan 18;14(1):33 |
Gatd3a glutamine amidotransferase like class 1 domain containing 3A (Synonyms: D10Jhu81e) | |
Results | Reference |
1 | J:343556 Kretschmer V, Schneider S, Matthiessen PA, Reichert D, Hotaling N, Glassser G, Lieberwirth I, Bharti K, De Cegli R, Conte I, Nandrot EF, May-Simera HL, Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration. PLoS Biol. 2023 Dec;21(12):e3002402 |
Gatm glycine amidinotransferase (L-arginine:glycine amidinotransferase) (Synonyms: 1810003P21Rik) | |
Results | Reference |
1* | J:83395 Sandell LL, Guan XJ, Ingram R, Tilghman SM, Gatm, a creatine synthesis enzyme, is imprinted in mouse placenta. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4622-7 |
Gba2 glucosidase beta 2 (Synonyms: bile acid) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Gbe1 1,4-alpha-glucan branching enzyme 1 (Synonyms: 2310045H19Rik, 2810426P10Rik, D16Ertd536e) | |
Results | Reference |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
Gbx1 gastrulation brain homeobox 1 (Synonyms: Gbx-1) | |
Results | Reference |
1 | J:201154 Meziane H, Fraulob V, Riet F, Krezel W, Selloum M, Geffarth M, Acampora D, Herault Y, Simeone A, Brand M, Dolle P, Rhinn M, The homeodomain factor Gbx1 is required for locomotion and cell specification in the dorsal spinal cord. PeerJ. 2013;1:e142 |
Gbx2 gastrulation brain homeobox 2 (Synonyms: Gbx-2, MMoxA, Stra7) | |
Results | Reference |
1* | J:121833 Bonnin A, Torii M, Wang L, Rakic P, Levitt P, Serotonin modulates the response of embryonic thalamocortical axons to netrin-1. Nat Neurosci. 2007 May;10(5):588-97 |
1* | J:286303 Buckley DM, Burroughs-Garcia J, Kriks S, Lewandoski M, Waters ST, Gbx1 and Gbx2 Are Essential for Normal Patterning and Development of Interneurons and Motor Neurons in the Embryonic Spinal Cord. J Dev Biol. 2020 Apr 1;8(2) |
1* | J:44718 Chapman G, Remiszewski JL, Webb GC, Schulz TC, Bottema CD, Rathjen PD, The mouse homeobox gene, Gbx2: genomic organization and expression in pluripotent cells in vitro and in vivo. Genomics. 1997 Dec 1;46(2):223-33 |
1 | J:189961 Chatterjee M, Li K, Chen L, Maisano X, Guo Q, Gan L, Li JY, Gbx2 regulates thalamocortical axon guidance by modifying the LIM and Robo codes. Development. 2012 Dec;139(24):4633-43 |
1 | J:147282 Chen L, Guo Q, Li JY, Transcription factor Gbx2 acts cell-nonautonomously to regulate the formation of lineage-restriction boundaries of the thalamus. Development. 2009 Apr;136(8):1317-26 |
1 | J:188332 Delogu A, Sellers K, Zagoraiou L, Bocianowska-Zbrog A, Mandal S, Guimera J, Rubenstein JL, Sugden D, Jessell T, Lumsden A, Subcortical visual shell nuclei targeted by ipRGCs develop from a Sox14+-GABAergic progenitor and require Sox14 to regulate daily activity rhythms. Neuron. 2012 Aug 23;75(4):648-62 |
1* | J:79830 Garel S, Yun K, Grosschedl R, Rubenstein JL, The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development. 2002 Dec;129(24):5621-34 |
1 | J:241012 Lee M, Yoon J, Song H, Lee B, Lam DT, Yoon J, Baek K, Clevers H, Jeong Y, Tcf7l2 plays crucial roles in forebrain development through regulation of thalamic and habenular neuron identity and connectivity. Dev Biol. 2017 Apr 01;424(1):62-76 |
1 | J:199727 Lokmane L, Proville R, Narboux-Neme N, Gyory I, Keita M, Mailhes C, Lena C, Gaspar P, Grosschedl R, Garel S, Sensory map transfer to the neocortex relies on pretarget ordering of thalamic axons. Curr Biol. 2013 May 6;23(9):810-6 |
1* | J:68840 Nakagawa Y, O'Leary DD, Combinatorial expression patterns of LIM-homeodomain and other regulatory genes parcellate developing thalamus. J Neurosci. 2001 Apr 15;21(8):2711-25 |
1 | J:296045 Patmore DM, Jassim A, Nathan E, Gilbertson RJ, Tahan D, Hoffmann N, Tong Y, Smith KS, Kanneganti TD, Suzuki H, Taylor MD, Northcott P, Gilbertson RJ, DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma. Dev Cell. 2020 Aug 24;54(4):455-470.e5 |
1* | J:287411 Tran HN, Park W, Seong S, Jeong JE, Nguyen QH, Yoon J, Baek K, Jeong Y, Tcf7l2 transcription factor is required for the maintenance, but not the initial specification, of the neurotransmitter identity in the caudal thalamus. Dev Dyn. 2020 May;249(5):646-655 |
1 | J:132518 Vue TY, Aaker J, Taniguchi A, Kazemzadeh C, Skidmore JM, Martin DM, Martin JF, Treier M, Nakagawa Y, Characterization of progenitor domains in the developing mouse thalamus. J Comp Neurol. 2007 Nov 1;505(1):73-91 |
1 | J:147427 Vue TY, Bluske K, Alishahi A, Yang LL, Koyano-Nakagawa N, Novitch B, Nakagawa Y, Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice. J Neurosci. 2009 Apr 8;29(14):4484-97 |
Gcg glucagon (Synonyms: GLP-1, Glu, glucagon-like peptide I, PPG) | |
Results | Reference |
1 | J:70719 Allen-Jennings AE, Hartman MG, Kociba GJ, Hai T, The roles of atf3 in glucose homeostasis. a transgenic mouse model with liver dysfunction and defects in endocrine pancreas. J Biol Chem. 2001 Aug 3;276(31):29507-14 |
2 | J:156329 Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L, Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. J Biol Chem. 2009 Nov 6;284(45):31236-48 |
1 | J:305792 Ansarullah, Jain C, Far FF, Homberg S, Wissmiller K, von Hahn FG, Raducanu A, Schirge S, Sterr M, Bilekova S, Siehler J, Wiener J, Oppenlander L, Morshedi A, Bastidas-Ponce A, Collden G, Irmler M, Beckers J, Feuchtinger A, Grzybek M, Ahlbrecht C, Feederle R, Plettenburg O, Muller TD, Meier M, Tschop MH, Coskun U, Lickert H, Inceptor counteracts insulin signalling in beta-cells to control glycaemia. Nature. 2021 Feb;590(7845):326-331 |
1 | J:119565 Boyer DF, Fujitani Y, Gannon M, Powers AC, Stein RW, Wright CV, Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression. Dev Biol. 2006 Oct 15;298(2):616-31 |
1 | J:116552 Brissova M, Shostak A, Shiota M, Wiebe PO, Poffenberger G, Kantz J, Chen Z, Carr C, Jerome WG, Chen J, Baldwin HS, Nicholson W, Bader DM, Jetton T, Gannon M, Powers AC, Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function. Diabetes. 2006 Nov;55(11):2974-85 |
1 | J:255164 Broche B, Ben Fradj S, Aguilar E, Sancerni T, Benard M, Makaci F, Berthault C, Scharfmann R, Alves-Guerra MC, Duvillie B, Mitochondrial Protein UCP2 Controls Pancreas Development. Diabetes. 2018 Jan;67(1):78-84 |
1 | J:200985 Cai EP, Wu X, Schroer SA, Elia AJ, Nostro MC, Zacksenhaus E, Woo M, Retinoblastoma tumor suppressor protein in pancreatic progenitors controls alpha- and beta-cell fate. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14723-8 |
1 | J:129103 Chao CS, Loomis ZL, Lee JE, Sussel L, Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells. Dev Biol. 2007 Dec 15;312(2):523-32 |
1 | J:105207 Chu K, Tsai MJ, Neuronatin, a downstream target of BETA2/NeuroD1 in the pancreas, is involved in glucose-mediated insulin secretion. Diabetes. 2005 Apr;54(4):1064-73 |
2 | J:220324 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C, Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 1;142(5):871-82 |
1 | J:119284 Decker K, Goldman DC, Grasch CL, Sussel L, Gata6 is an important regulator of mouse pancreas development. Dev Biol. 2006 Oct 15;298(2):415-29 |
1 | J:209744 Diaferia GR, Cirulli V, Biunno I, SEL1L regulates adhesion, proliferation and secretion of insulin by affecting integrin signaling. PLoS One. 2013;8(11):e79458 |
2 | J:119914 Doyle MJ, Loomis ZL, Sussel L, Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet. Development. 2007 Feb;134(3):515-23 |
1 | J:141158 Fontaniere S, Duvillie B, Scharfmann R, Carreira C, Wang ZQ, Zhang CX, Tumour suppressor menin is essential for development of the pancreatic endocrine cells. J Endocrinol. 2008 Nov;199(2):287-98 |
2* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1* | J:191140 Grigoryan M, Kedees MH, Guz Y, Teitelman G, Phenotype of entero-endocrine L cells becomes restricted during development. Dev Dyn. 2012 Dec;241(12):1986-92 |
1 | J:134078 Hezel AF, Gurumurthy S, Granot Z, Swisa A, Chu GC, Bailey G, Dor Y, Bardeesy N, Depinho RA, Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. Mol Cell Biol. 2008 Apr;28(7):2414-25 |
2* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
2 | J:257425 Kim DS, Song L, Wang J, Wu H, Gu G, Sugi Y, Li Z, Wang H, GRP94 Is an Essential Regulator of Pancreatic beta-Cell Development, Mass, and Function in Male Mice. Endocrinology. 2018 Feb 1;159(2):1062-1073 |
1 | J:112755 Kim HJ, Schleiffarth JR, Jessurun J, Sumanas S, Petryk A, Lin S, Ekker SC, Wnt5 signaling in vertebrate pancreas development. BMC Biol. 2005;3:23 |
1* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
1 | J:306907 Kodani N, Nakae J, Kobayashi M, Kikuchi O, Kitamura T, Itoh H, FCoR-Foxo1 Axis Regulates alpha-Cell Mass through Repression of Arx Expression. iScience. 2020 Jan 24;23(1):100798 |
1 | J:176201 Kordowich S, Collombat P, Mansouri A, Serup P, Arx and Nkx2.2 compound deficiency redirects pancreatic alpha- and beta-cell differentiation to a somatostatin/ghrelin co-expressing cell lineage. BMC Dev Biol. 2011;11:52 |
1 | J:272578 Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G, Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. Dev Cell. 2019 Jan 7;48(1):49-63.e7 |
2 | J:290417 Lorberbaum DS, Kishore S, Rosselot C, Sarbaugh D, Brooks EP, Aragon E, Xuan S, Simon O, Ghosh D, Mendelsohn C, Gadue P, Sussel L, Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human beta cell specification. Development. 2020 Jun 22;147(12):dev189977 |
1 | J:63347 Maldonado TS, Kadison AS, Crisera CA, Grau JB, Alkasab SL, Longaker MT, Gittes GK, Ontogeny of activin B and follistatin in developing embryonic mouse pancreas: implications for lineage selection. J Gastrointest Surg. 2000 May-Jun;4(3):269-75 |
1 | J:227268 Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Bjorklund P, Mackie K, Di Marzo V, Hokfelt TG, Dobrzyn A, Harkany T, Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6185-94 |
1 | J:62160 Miettinen PJ, Huotari M, Koivisto T, Ustinov J, Palgi J, Rasilainen S, Lehtonen E, Keski-Oja J, Otonkoski T, Impaired migration and delayed differentiation of pancreatic islet cells in mice lacking EGF-receptors. Development. 2000 Jun;127(12):2617-27 |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
1* | J:130176 Nammo T, Yamagata K, Tanaka T, Kodama T, Sladek FM, Fukui K, Katsube F, Sato Y, Miyagawa J, Shimomura I, Expression of HNF-4alpha (MODY1), HNF-1beta (MODY5), and HNF-1alpha (MODY3) proteins in the developing mouse pancreas. Gene Expr Patterns. 2008 Jan;8(2):96-106 |
1 | J:253982 Norlin S, Parekh V, Edlund H, The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival. Development. 2018 Jan 3;145(1):dev154468 |
1* | J:32017 Offield MF, Jetton TL, Labosky PA, Ray M, Stein RW, Magnuson MA, Hogan BL, Wright CV, PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development. 1996 Mar;122(3):983-95 |
1 | J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461 |
1 | J:246400 Paul L, Walker EM, Drosos Y, Cyphert HA, Neale G, Stein R, South J, Grosveld G, Herrera PL, Sosa-Pineda B, Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine beta-Cells. Diabetes. 2016 Mar;65(3):687-98 |
1 | J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356 |
1 | J:243381 Serafimidis I, Rodriguez-Aznar E, Lesche M, Yoshioka K, Takuwa Y, Dahl A, Pan D, Gavalas A, Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. PLoS Biol. 2017 Mar;15(3):e2000949 |
1 | J:141017 Seymour PA, Freude KK, Dubois CL, Shih HP, Patel NA, Sander M, A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation. Dev Biol. 2008 Nov 1;323(1):19-30 |
2 | J:338071 Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn LJ, Rosenthal B, Gurtler M, Estanboulieh RR, Shvartsman D, Gifford DK, Trapnell C, Melton D, A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets. Cell. 2019 Feb 7;176(4):790-804.e13 |
1 | J:151981 Spence JR, Lange AW, Lin SC, Kaestner KH, Lowy AM, Kim I, Whitsett JA, Wells JM, Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell. 2009 Jul;17(1):62-74 |
1 | J:147764 Svensson P, Bergqvist I, Norlin S, Edlund H, MFng is dispensable for mouse pancreas development and function. Mol Cell Biol. 2009 Apr;29(8):2129-38 |
1 | J:186391 Tao J, Zhu M, Wang H, Afelik S, Vasievich MP, Chen XW, Zhu G, Jensen J, Ginsburg D, Zhang B, SEC23B is required for the maintenance of murine professional secretory tissues. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):E2001-9 |
1 | J:307817 Theis A, Singer RA, Garofalo D, Paul A, Narayana A, Sussel L, Groucho co-repressor proteins regulate beta cell development and proliferation by repressing Foxa1 in the developing mouse pancreas. Development. 2021 Mar 24;148(6):dev192401 |
1 | J:333324 Tominaga K, Sakashita E, Kasashima K, Kuroiwa K, Nagao Y, Iwamori N, Endo H, Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells. Int J Mol Sci. 2023 Jan 20;24(3) |
1 | J:208719 Tsai MJ, Yang-Yen HF, Chiang MK, Wang MJ, Wu SS, Chen SH, TCTP is essential for beta-cell proliferation and mass expansion during development and beta-cell adaptation in response to insulin resistance. Endocrinology. 2014 Feb;155(2):392-404 |
1 | J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521 |
1 | J:225743 Um SH, Sticker-Jantscheff M, Chau GC, Vintersten K, Mueller M, Gangloff YG, Adams RH, Spetz JF, Elghazi L, Pfluger PT, Pende M, Bernal-Mizrachi E, Tauler A, Tschop MH, Thomas G, Kozma SC, S6K1 controls pancreatic beta cell size independently of intrauterine growth restriction. J Clin Invest. 2015 Jul 1;125(7):2736-47 |
1 | J:342871 Xiang J, Pompetti AJ, Faranda AP, Wang Y, Novo SG, Li DW, Duncan MK, ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment. Cells. 2023 Nov 16;12(22) |
1 | J:364195 Yang L, Yu XX, Wang X, Jin CT, Xu CR, The expression order determines the pioneer functions of NGN3 and NEUROD1 in pancreatic endocrine differentiation. Sci Adv. 2025 Mar 28;11(13):eadt4770 |
1 | J:174673 Yang YP, Thorel F, Boyer DF, Herrera PL, Wright CV, Context-specific {alpha}-to-{beta}-cell reprogramming by forced Pdx1 expression. Genes Dev. 2011 Aug 15;25(16):1680-5 |
1 | J:144661 Zhang W, Feng D, Li Y, Iida K, McGrath B, Cavener DR, PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis. Cell Metab. 2006 Dec;4(6):491-7 |
Gck glucokinase (Synonyms: Gls006, hexokinase 4, HK4, Hlb62, MODY2) | |
Results | Reference |
2* | J:132397 Cifuentes D, Martinez-Pons C, Garcia-Rocha M, Galina A, de Pouplana LR, Guinovart JJ, Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver. J Biol Chem. 2008 Feb 29;283(9):5642-9 |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
Gclc glutamate-cysteine ligase, catalytic subunit (Synonyms: D9Wsu168e, gamma GCS-HS, Glclc, GLCL-H) | |
Results | Reference |
4* | J:93103 Diaz D, Krejsa CM, White CC, Charleston JS, Kavanagh TJ, Effect of methylmercury on glutamate-cysteine ligase expression in the placenta and yolk sac during mouse development. Reprod Toxicol. 2004 Nov;19(1):117-29 |
1* | J:191045 Huebner AJ, Dai D, Morasso M, Schmidt EE, Schafer M, Werner S, Roop DR, Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero. Dev Cell. 2012 Dec 11;23(6):1238-46 |
2* | J:74071 Thompson SA, White CC, Krejsa CM, Eaton DL, Kavanagh TJ, Modulation of glutathione and glutamate-L-cysteine ligase by methylmercury during mouse development. Toxicol Sci. 2000 Sep;57(1):141-6 |
Gclm glutamate-cysteine ligase, modifier subunit (Synonyms: Gcmc, Glclr) | |
Results | Reference |
2* | J:93103 Diaz D, Krejsa CM, White CC, Charleston JS, Kavanagh TJ, Effect of methylmercury on glutamate-cysteine ligase expression in the placenta and yolk sac during mouse development. Reprod Toxicol. 2004 Nov;19(1):117-29 |
1* | J:74071 Thompson SA, White CC, Krejsa CM, Eaton DL, Kavanagh TJ, Modulation of glutathione and glutamate-L-cysteine ligase by methylmercury during mouse development. Toxicol Sci. 2000 Sep;57(1):141-6 |
Gcm1 glial cells missing homolog 1 (Synonyms: Gcm 1, Gcm1-rs1, Gcm a, GCMa, glial cell deficient, glide) | |
Results | Reference |
1 | J:180242 Dupressoir A, Vernochet C, Harper F, Guegan J, Dessen P, Pierron G, Heidmann T, A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1164-73 |
2* | J:79509 Hashemolhosseini S, Hadjihannas M, Stolt C, Haas C, Amann K, Wegner M, Restricted expression of mouse GCMa/Gcm1 in kidney and thymus. Mech Dev. 2002 Oct;118(1-2):175 |
1* | J:50339 Kim J, Jones BW, Zock C, Chen Z, Wang H, Goodman CS, Anderson DJ, Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12364-9 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
1 | J:205632 Saito A, Kanemoto S, Kawasaki N, Asada R, Iwamoto H, Oki M, Miyagi H, Izumi S, Sanosaka T, Nakashima K, Imaizumi K, Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun. 2012;3:967 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
Gcm2 glial cells missing homolog 2 (Synonyms: Gcm1-rs2) | |
Results | Reference |
1 | J:304609 Caprio C, Lania G, Bilio M, Ferrentino R, Chen L, Baldini A, EZH2 is required for parathyroid and thymic development through differentiation of the third pharyngeal pouch endoderm. Dis Model Mech. 2021 Feb 19;:dmm.046789 |
2* | J:50339 Kim J, Jones BW, Zock C, Chen Z, Wang H, Goodman CS, Anderson DJ, Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12364-9 |
1* | J:167511 Liu Z, Farley A, Chen L, Kirby BJ, Kovacs CS, Blackburn CC, Manley NR, Thymus-associated parathyroid hormone has two cellular origins with distinct endocrine and immunological functions. PLoS Genet. 2010;6(12):e1001251 |
Gcna germ cell nuclear acidic protein (Synonyms: Gcna1, Gm52429) | |
Results | Reference |
1* | J:133516 Alton M, Lau MP, Villemure M, Taketo T, The behavior of the X- and Y-chromosomes in the oocyte during meiotic prophase in the B6.Y(TIR)sex-reversed mouse ovary. Reproduction. 2008 Feb;135(2):241-52 |
1 | J:359451 Amato CM, Xu X, Yao HH, An extragenital cell population contributes to urethra closure during mouse penis development. Sci Adv. 2024 Dec 6;10(49):eadp0673 |
1 | J:134687 Chang H, Gao F, Guillou F, Taketo MM, Huff V, Behringer RR, Wt1 negatively regulates {beta}-catenin signaling during testis development. Development. 2008 May;135(10):1875-85 |
1* | J:305426 Du G, Oatley MJ, Law NC, Robbins C, Wu X, Oatley JM, Proper timing of a quiescence period in precursor prospermatogonia is required for stem cell pool establishment in the male germline. Development. 2021 May 1;148(9):dev194571 |
1* | J:18484 Enders GC, May JJ 2nd, Developmentally regulated expression of a mouse germ cell nuclear antigen examined from embryonic day 11 to adult in male and female mice. Dev Biol. 1994 Jun;163(2):331-40 |
1 | J:196310 Ene AC, Park S, Edelmann W, Taketo T, Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression. Dev Biol. 2013 May 1;377(1):213-23 |
1 | J:342170 Gura MA, Bartholomew MA, Abt KM, Relovska S, Seymour KA, Freiman RN, Transcription and chromatin regulation by TAF4b during cellular quiescence of developing prospermatogonia. Front Cell Dev Biol. 2023;11:1270408 |
1 | J:330390 Gura MA, Relovska S, Abt KM, Seymour KA, Wu T, Kaya H, Turner JMA, Fazzio TG, Freiman RN, TAF4b transcription networks regulating early oocyte differentiation. Development. 2022 Feb 1;149(3):dev200074 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1* | J:215225 Koubova J, Hu YC, Bhattacharyya T, Soh YQ, Gill ME, Goodheart ML, Hogarth CA, Griswold MD, Page DC, Retinoic acid activates two pathways required for meiosis in mice. PLoS Genet. 2014 Aug;10(8):e1004541 |
1 | J:294981 Liu X, Castle V, Taketo T, Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development. Cell Death Dis. 2019 Oct 17;10(11):790 |
1* | J:64334 Nadler JJ, Braun RE, Fanconi anemia complementation group C is required for proliferation of murine primordial germ cells [letter]. Genesis. 2000 Jul;27(3):117-23 |
1 | J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34 |
1* | J:72502 Perez-Armendariz EM, Lamoyi E, Mason JI, Cisneros-Armas D, Luu-The V, Bravo Moreno JF, Developmental regulation of connexin 43 expression in fetal mouse testicular cells. Anat Rec. 2001 Nov 1;264(3):237-46 |
1 | J:205334 Saba R, Kato Y, Saga Y, NANOS2 promotes male germ cell development independent of meiosis suppression. Dev Biol. 2014 Jan 1;385(1):32-40 |
1* | J:209131 Saba R, Wu Q, Saga Y, CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways. Dev Biol. 2014 May 15;389(2):173-81 |
1 | J:187029 Suzuki A, Saba R, Miyoshi K, Morita Y, Saga Y, Interaction between NANOS2 and the CCR4-NOT deadenylation complex is essential for male germ cell development in mouse. PLoS One. 2012;7(3):e33558 |
1 | J:306454 Tan K, Kim ME, Song HW, Skarbrevik D, Babajanian E, Bedrosian TA, Gage FH, Wilkinson MF, The Rhox gene cluster suppresses germline LINE1 transposition. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2024785118 |
1 | J:83946 Tay J, Hodgman R, Sarkissian M, Richter JD, Regulated CPEB phosphorylation during meiotic progression suggests a mechanism for temporal control of maternal mRNA translation. Genes Dev. 2003 Jun 15;17(12):1457-62 |
1 | J:102097 Tay J, Richter JD, Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice. Dev Cell. 2001 Aug;1(2):201-13 |
1 | J:32051 Wang D, Enders GC, Expression of a specific mouse germ cell nuclear antigen (GCNA1) by early embryonic testicular teratoma cells in 129/Sv-Sl/+ mice. Cancer Lett. 1996 Feb 27;100(1-2):31-6 |
1 | J:286995 Wang YQ, Cheng JM, Wen Q, Tang JX, Li J, Chen SR, Liu YX, An exploration of the role of Sertoli cells on fetal testis development using cell ablation strategy. Mol Reprod Dev. 2020 Feb;87(2):223-230 |
1 | J:223223 Wu Q, Fukuda K, Weinstein M, Graff JM, Saga Y, SMAD2 and p38 signaling pathways act in concert to determine XY primordial germ cell fate in mice. Development. 2015 Feb 1;142(3):575-86 |
1 | J:356758 Yamaguchi S, Hong K, Liu R, Inoue A, Shen L, Zhang K, Zhang Y, Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming. Cell Res. 2013 Mar;23(3):329-39 |
1 | J:194101 Yamaguchi S, Hong K, Liu R, Shen L, Inoue A, Diep D, Zhang K, Zhang Y, Tet1 controls meiosis by regulating meiotic gene expression. Nature. 2012 Dec 20;492(7429):443-7 |
1* | J:98712 Yamaguchi S, Kimura H, Tada M, Nakatsuji N, Tada T, Nanog expression in mouse germ cell development. Gene Expr Patterns. 2005 Jun;5(5):639-646 |
1* | J:124279 Zhang B, Jain S, Song H, Fu M, Heuckeroth RO, Erlich JM, Jay PY, Milbrandt J, Mice lacking sister chromatid cohesion protein PDS5B exhibit developmental abnormalities reminiscent of Cornelia de Lange syndrome. Development. 2007 Sep;134(17):3191-201 |
Gdf1 growth differentiation factor 1 (Synonyms: Gdf-1) | |
Results | Reference |
2* | J:317045 Cheng W, Li HL, Xi SY, Zhang XF, Zhu Y, Le Xing, Mo YX, Li MM, Kong FE, Zhu WJ, Chen XG, Cui HQ, Cao ZM, Gong YF, Tang YQ, Zhang Y, Guan XY, Ma NF, Liu M, Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma. Nat Commun. 2021 Dec 8;12(1):7142 |
1* | J:11181 Lee SJ, Expression of growth/differentiation factor 1 in the nervous system: conservation of a bicistronic structure. Proc Natl Acad Sci U S A. 1991 May 15;88(10):4250-4 |
1 | J:60755 Rankin CT, Bunton T, Lawler AM, Lee SJ, Regulation of left-right patterning in mice by growth/differentiation factor-1. Nat Genet. 2000 Mar;24(3):262-5 |
Gdf3 growth differentiation factor 3 (Synonyms: ecat9, Gdf-3, Vgr-2, Vgr2) | |
Results | Reference |
1* | J:3327 Jones CM, Simon-Chazottes D, Guenet JL, Hogan BL, Isolation of Vgr-2, a novel member of the transforming growth factor-beta-related gene family. Mol Endocrinol. 1992 Nov;6(11):1961-8 |
Gdf5 growth differentiation factor 5 (Synonyms: bp, brp, cartilage-derived morphogenetic protein-1, CDMP-1) | |
Results | Reference |
1* | J:75699 Albrecht AN, Schwabe GC, Stricker S, Boddrich A, Wanker EE, Mundlos S, The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67 |
1 | J:48000 Brunet LJ, McMahon JA, McMahon AP, Harland RM, Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton [see comments]. Science. 1998 May 29;280(5368):1455-7 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1 | J:160493 Dy P, Smits P, Silvester A, Penzo-Mendez A, Dumitriu B, Han Y, de la Motte CA, Kingsley DM, Lefebvre V, Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. Dev Biol. 2010 May 15;341(2):346-59 |
1 | J:272612 Eyal S, Rubin S, Krief S, Levin L, Zelzer E, Common cellular origin and diverging developmental programs for different sesamoid bones. Development. 2019 Feb 28;146(4):dev167452 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:132023 Hwang CH, Wu DK, Noggin heterozygous mice: an animal model for congenital conductive hearing loss in humans. Hum Mol Genet. 2008 Mar 15;17(6):844-53 |
1* | J:326033 Kim M, Koyama E, Saunders CM, Querido W, Pleshko N, Pacifici M, Synovial joint cavitation initiates with microcavities in interzone and is coupled to skeletal flexion and elongation in developing mouse embryo limbs. Biol Open. 2022 Jun 15;11(6):bio059381 |
1* | J:81315 Kunath M, Ludecke HJ, Vortkamp A, Expression of Trps1 during mouse embryonic development. Mech Dev. 2002 Dec;119 Suppl 1:S117-20 |
1 | J:346064 Leung AOW, Poon ACH, Wang X, Feng C, Chen P, Zheng Z, To MK, Chan WCW, Cheung M, Chan D, Suppression of apoptosis impairs phalangeal joint formation in the pathogenesis of brachydactyly type A1. Nat Commun. 2024 Mar 12;15(1):2229 |
1 | J:324217 Mead TJ, Martin DR, Wang LW, Cain SA, Gulec C, Cahill E, Mauch J, Reinhardt D, Lo C, Baldock C, Apte SS, Proteolysis of fibrillin-2 microfibrils is essential for normal skeletal development. Elife. 2022 May 3;11:e71142 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1 | J:238878 Ray A, Singh PN, Sohaskey ML, Harland RM, Bandyopadhyay A, Precise spatial restriction of BMP signaling is essential for articular cartilage differentiation. Development. 2015 Mar 15;142(6):1169-79 |
1 | J:96756 Rhee DK, Marcelino J, Baker M, Gong Y, Smits P, Lefebvre V, Jay GD, Stewart M, Wang H, Warman ML, Carpten JD, The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth. J Clin Invest. 2005 Mar;115(3):622-31 |
1* | J:273042 Rigueur D, Roberts RR, Bobzin L, Merrill AE, A requirement for Fgfr2 in middle ear development. Genesis. 2019 Jan;57(1):e23252 |
2* | J:83132 Settle SH Jr, Rountree RB, Sinha A, Thacker A, Higgins K, Kingsley DM, Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes. Dev Biol. 2003 Feb 1;254(1):116-30 |
1 | J:357740 Sorsby M, Almardini S, Alayyat A, Hughes A, Venkat S, Rahman M, Baker J, Rana R, Rosen V, Liu ES, The role of GDF5 in regulating enthesopathy development in the Hyp mouse model of XLH. J Bone Miner Res. 2024 Aug 21;39(8):1162-1173 |
1 | J:134924 Spagnoli A, O'Rear L, Chandler RL, Granero-Molto F, Mortlock DP, Gorska AE, Weis JA, Longobardi L, Chytil A, Shimer K, Moses HL, TGF-beta signaling is essential for joint morphogenesis. J Cell Biol. 2007 Jun 18;177(6):1105-17 |
1* | J:146224 Staverosky JA, Pryce BA, Watson SS, Schweitzer R, Tubulin polymerization-promoting protein family member 3, Tppp3, is a specific marker of the differentiating tendon sheath and synovial joints. Dev Dyn. 2009 Mar;238(3):685-92 |
1 | J:52419 Tsumaki N, Tanaka K, Arikawa-Hirasawa E, Nakase T, Kimura T, Thomas JT, Ochi T, Luyten FP, Yamada Y, Role of CDMP-1 in skeletal morphogenesis: promotion of mesenchymal cell recruitment and chondrocyte differentiation. J Cell Biol. 1999 Jan 11;144(1):161-73 |
1 | J:161451 Villavicencio-Lorini P, Kuss P, Friedrich J, Haupt J, Farooq M, Turkmen S, Duboule D, Hecht J, Mundlos S, Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. J Clin Invest. 2010 Jun 1;120(6):1994-2004 |
Gdf6 growth differentiation factor 6 (Synonyms: BMP13) | |
Results | Reference |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
2* | J:83132 Settle SH Jr, Rountree RB, Sinha A, Thacker A, Higgins K, Kingsley DM, Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes. Dev Biol. 2003 Feb 1;254(1):116-30 |
Gdf7 growth differentiation factor 7 (Synonyms: BMP12) | |
Results | Reference |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1* | J:83132 Settle SH Jr, Rountree RB, Sinha A, Thacker A, Higgins K, Kingsley DM, Multiple joint and skeletal patterning defects caused by single and double mutations in the mouse Gdf6 and Gdf5 genes. Dev Biol. 2003 Feb 1;254(1):116-30 |
Gdf9 growth differentiation factor 9 (Synonyms: Gdf-9) | |
Results | Reference |
1* | J:152501 Wang Y, Nicholls PK, Stanton PG, Harrison CA, Sarraj M, Gilchrist RB, Findlay JK, Farnworth PG, Extra-ovarian expression and activity of growth differentiation factor 9. J Endocrinol. 2009 Sep;202(3):419-30 |
Gdf10 growth differentiation factor 10 (Synonyms: Bmp3b) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
3 | J:214970 Mecklenburg N, Martinez-Lopez JE, Moreno-Bravo JA, Perez-Balaguer A, Puelles E, Martinez S, Growth and differentiation factor 10 (Gdf10) is involved in Bergmann glial cell development under Shh regulation. Glia. 2014 Oct;62(10):1713-23 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:56683 Zhao R, Lawler AM, Lee SJ, Characterization of GDF-10 expression patterns and null mice. Dev Biol. 1999 Aug 1;212(1):68-79 |
Gdf11 growth differentiation factor 11 (Synonyms: Bmp11) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:147995 Kawauchi S, Kim J, Santos R, Wu HH, Lander AD, Calof AL, Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11. Development. 2009 May;136(9):1453-64 |
Gdf15 growth differentiation factor 15 (Synonyms: macrophage inhibiting cytokine-1, MIC-1, NAG-1) | |
Results | Reference |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
2 | J:119728 Noorali S, Kurita T, Woolcock B, de Algara TR, Lo M, Paralkar V, Hoodless P, Vielkind J, Dynamics of expression of growth differentiation factor 15 in normal and PIN development in the mouse. Differentiation. 2007 Apr;75(4):325-36 |
Gdi1 GDP dissociation inhibitor 1 (Synonyms: GDIA, MGC:21593, Rab GDIalpha) | |
Results | Reference |
2* | J:24938 Bachner D, Sedlacek Z, Korn B, Hameister H, Poustka A, Expression patterns of two human genes coding for different rab GDP-dissociation inhibitors (GDIs), extremely conserved proteins involved in cellular transport. Hum Mol Genet. 1995 Apr;4(4):701-8 |
Gdi2 GDP dissociation inhibitor 2 (Synonyms: Gdi3, GDI-B, GDIB, GDI beta) | |
Results | Reference |
2* | J:24938 Bachner D, Sedlacek Z, Korn B, Hameister H, Poustka A, Expression patterns of two human genes coding for different rab GDP-dissociation inhibitors (GDIs), extremely conserved proteins involved in cellular transport. Hum Mol Genet. 1995 Apr;4(4):701-8 |
Gdnf glial cell line derived neurotrophic factor (Synonyms: glial cell line-derived neurotrophic factor) | |
Results | Reference |
1 | J:124898 Ai X, Kitazawa T, Do AT, Kusche-Gullberg M, Labosky PA, Emerson CP Jr, SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation. Development. 2007 Sep;134(18):3327-38 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
2 | J:196581 Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G, The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-beta signaling. Dev Biol. 2013 May 15;377(2):415-27 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:291050 Ide S, Finer G, Maezawa Y, Onay T, Souma T, Scott R, Ide K, Akimoto Y, Li C, Ye M, Zhao X, Baba Y, Minamizuka T, Jin J, Takemoto M, Yokote K, Quaggin SE, Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development. J Am Soc Nephrol. 2018 Dec;29(12):2795-2808 |
1 | J:246806 Li Y, Zhang L, Hu Y, Chen M, Han F, Qin Y, Chen M, Cui X, Duo S, Tang F, Gao F, beta-Catenin directs the transformation of testis Sertoli cells to ovarian granulosa-like cells by inducing Foxl2 expression. J Biol Chem. 2017 Oct 27;292(43):17577-17586 |
1 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
1 | J:120229 Narlis M, Grote D, Gaitan Y, Boualia SK, Bouchard M, Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney. J Am Soc Nephrol. 2007 Apr;18(4):1121-9 |
2 | J:223235 Park HJ, Bolton EC, Glial cell line-derived neurotrophic factor induces cell proliferation in the mouse urogenital sinus. Mol Endocrinol. 2015 Feb;29(2):289-306 |
1 | J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Gdpd2 glycerophosphodiester phosphodiesterase domain containing 2 (Synonyms: 9130017L10Rik, GDE3) | |
Results | Reference |
1 | J:291492 Dobrowolski M, Cave C, Levy-Myers R, Lee C, Park S, Choi BR, Xiao B, Yang W, Sockanathan S, GDE3 regulates oligodendrocyte precursor proliferation via release of soluble CNTFRalpha. Development. 2020 Jan 23;147(2):dev180695 |
Gemin2 gem nuclear organelle associated protein 2 (Synonyms: 1700012N19Rik, Sip1) | |
Results | Reference |
1 | J:182704 Weng Q, Chen Y, Wang H, Xu X, Yang B, He Q, Shou W, Chen Y, Higashi Y, van den Berghe V, Seuntjens E, Kernie SG, Bukshpun P, Sherr EH, Huylebroeck D, Lu QR, Dual-mode modulation of Smad signaling by Smad-interacting protein Sip1 is required for myelination in the central nervous system. Neuron. 2012 Feb 23;73(4):713-28 |
Gen1 GEN1, Holliday junction 5' flap endonuclease (Synonyms: 5830483C08Rik) | |
Results | Reference |
1* | J:309152 Wang X, Wang H, Liu J, Gong Y, Zhang C, Fang F, Li A, Wu X, Shen Q, Xu H, Gen1 mutation caused kidney hypoplasia and defective ureter-bladder connections in mice. Int J Biol Sci. 2020;16(9):1640-1647 |
Gfap glial fibrillary acidic protein | |
Results | Reference |
1 | J:195145 Amaniti EM, Hasenpusch-Theil K, Li Z, Magnani D, Kessaris N, Mason JO, Theil T, Gli3 is required in Emx1(+) progenitors for the development of the corpus callosum. Dev Biol. 2013 Apr 15;376(2):113-24 |
1 | J:181188 Aoki H, Hara A, Era T, Kunisada T, Yamada Y, Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development. 2012 Feb;139(4):667-77 |
1 | J:107695 Bagri A, Marin O, Plump AS, Mak J, Pleasure SJ, Rubenstein JL, Tessier-Lavigne M, Slit proteins prevent midline crossing and determine the dorsoventral position of major axonal pathways in the mammalian forebrain. Neuron. 2002 Jan 17;33(2):233-48 |
1 | J:109287 Balmer CW, LaMantia AS, Loss of Gli3 and Shh function disrupts olfactory axon trajectories. J Comp Neurol. 2004 May 3;472(3):292-307 |
1* | J:142365 Barry G, Piper M, Lindwall C, Moldrich R, Mason S, Little E, Sarkar A, Tole S, Gronostajski RM, Richards LJ, Specific glial populations regulate hippocampal morphogenesis. J Neurosci. 2008 Nov 19;28(47):12328-40 |
1 | J:183848 Benadiba C, Magnani D, Niquille M, Morle L, Valloton D, Nawabi H, Ait-Lounis A, Otsmane B, Reith W, Theil T, Hornung JP, Lebrand C, Durand B, The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development. PLoS Genet. 2012 Mar;8(3):e1002606 |
1 | J:199451 Brunne B, Franco S, Bouche E, Herz J, Howell BW, Pahle J, Muller U, May P, Frotscher M, Bock HH, Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by reelin signaling mutant mice. Glia. 2013 Aug;61(8):1347-63 |
1 | J:167274 Brunne B, Zhao S, Derouiche A, Herz J, May P, Frotscher M, Bock HH, Origin, maturation, and astroglial transformation of secondary radial glial cells in the developing dentate gyrus. Glia. 2010 Oct;58(13):1553-69 |
1 | J:337815 Bunt J, Osinski JM, Lim JW, Vidovic D, Ye Y, Zalucki O, O'Connor TR, Harris L, Gronostajski RM, Richards LJ, Piper M, Combined allelic dosage of Nfia and Nfib regulates cortical development. Brain Neurosci Adv. 2017 Jan-Dec;1:2398212817739433 |
1* | J:150043 Bush JO, Soriano P, Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Genes Dev. 2009 Jul 1;23(13):1586-99 |
1 | J:313961 Caramello A, Galichet C, Rizzoti K, Lovell-Badge R, Dentate gyrus development requires a cortical hem-derived astrocytic scaffold. Elife. 2021 Jan 4;10:e63904 |
1 | J:121201 Chen L, Liao G, Waclaw RR, Burns KA, Linquist D, Campbell K, Zheng Y, Kuan CY, Rac1 controls the formation of midline commissures and the competency of tangential migration in ventral telencephalic neurons. J Neurosci. 2007 Apr 4;27(14):3884-93 |
1 | J:182705 Choe Y, Siegenthaler JA, Pleasure SJ, A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Neuron. 2012 Feb 23;73(4):698-712 |
1 | J:169370 Conway CD, Howe KM, Nettleton NK, Price DJ, Mason JO, Pratt T, Heparan sulfate sugar modifications mediate the functions of slits and other factors needed for mouse forebrain commissure development. J Neurosci. 2011 Feb 9;31(6):1955-70 |
1* | J:361965 Fujimoto T, Mori M, Tonosaki M, Yaoi T, Nakano K, Okamura T, Itoh K, Characterization of Dystrophin Dp71 Expression and Interaction Partners in Embryonic Brain Development: Implications for Duchenne/Becker Muscular Dystrophy. Mol Neurobiol. 2025 Jan 6; |
1 | J:219427 Glasgow SM, Zhu W, Stolt CC, Huang TW, Chen F, LoTurco JJ, Neul JL, Wegner M, Mohila C, Deneen B, Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subtypes. Nat Neurosci. 2014 Oct;17(10):1322-9 |
1 | J:240770 Gobius I, Morcom L, Suarez R, Bunt J, Bukshpun P, Reardon W, Dobyns WB, Rubenstein JL, Barkovich AJ, Sherr EH, Richards LJ, Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum. Cell Rep. 2016 Oct 11;17(3):735-747 |
1* | J:243644 Gobius I, Suarez R, Morcom L, Paolino A, Edwards TJ, Kozulin P, Richards LJ, Astroglial-mediated remodeling of the interhemispheric midline during telencephalic development is exclusive to eutherian mammals. Neural Dev. 2017 May 30;12(1):9 |
1 | J:229411 Hakanen J, Salminen M, Defects in neural guidepost structures and failure to remove leptomeningeal cells from the septal midline behind the interhemispheric fusion defects in Netrin1 deficient mice. Int J Dev Neurosci. 2015 Dec;47(Pt B):206-15 |
1 | J:293063 Hamashima T, Ishii Y, Nguyen LQ, Okuno N, Sang Y, Matsushima T, Kurashige Y, Takebayashi H, Mori H, Fujimori T, Yamamoto S, Sasahara M, Oligodendrogenesis and Myelin Formation in the Forebrain Require Platelet-derived Growth Factor Receptor-alpha. Neuroscience. 2020 Jun 1;436:11-26 |
1 | J:181942 Hirai S, Miwa A, Ohtaka-Maruyama C, Kasai M, Okabe S, Hata Y, Okado H, RP58 controls neuron and astrocyte differentiation by downregulating the expression of Id1-4 genes in the developing cortex. EMBO J. 2012 Mar 7;31(5):1190-202 |
1 | J:212725 Hong S, Song MR, STAT3 but not STAT1 is required for astrocyte differentiation. PLoS One. 2014;9(1):e86851 |
1 | J:218888 Hong S, Song MR, Signal transducer and activator of transcription-3 maintains the stemness of radial glia at mid-neurogenesis. J Neurosci. 2015 Jan 21;35(3):1011-23 |
1* | J:320379 Ito H, Morishita R, Noda M, Iwamoto I, Nagata KI, Biochemical and morphological characterization of SEPT1 in mouse brain. Med Mol Morphol. 2020 Dec;53(4):221-228 |
1 | J:170546 Kaltezioti V, Kouroupi G, Oikonomaki M, Mantouvalou E, Stergiopoulos A, Charonis A, Rohrer H, Matsas R, Politis PK, Prox1 regulates the notch1-mediated inhibition of neurogenesis. PLoS Biol. 2010;8(12):e1000565 |
1 | J:209564 Karaca E, Weitzer S, Pehlivan D, Shiraishi H, Gogakos T, Hanada T, Jhangiani SN, Wiszniewski W, Withers M, Campbell IM, Erdin S, Isikay S, Franco LM, Gonzaga-Jauregui C, Gambin T, Gelowani V, Hunter JV, Yesil G, Koparir E, Yilmaz S, Brown M, Briskin D, Hafner M, Morozov P, Farazi TA, Bernreuther C, Glatzel M, Trattnig S, Friske J, Kronnerwetter C, Bainbridge MN, Gezdirici A, Seven M, Muzny DM, Boerwinkle E, Ozen M, Clausen T, Tuschl T, Yuksel A, Hess A, Gibbs RA, Martinez J, Penninger JM, Lupski JR, Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function. Cell. 2014 Apr 24;157(3):636-50 |
1 | J:126547 Ke Y, Zhang EE, Hagihara K, Wu D, Pang Y, Klein R, Curran T, Ranscht B, Feng GS, Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality. Mol Cell Biol. 2007 Oct;27(19):6706-17 |
1* | J:109511 Kimura I, Konishi M, Miyake A, Fujimoto M, Itoh N, Neudesin, a secreted factor, promotes neural cell proliferation and neuronal differentiation in mouse neural precursor cells. J Neurosci Res. 2006 Jun;83(8):1415-24 |
1 | J:166777 Lavado A, Lagutin OV, Chow LM, Baker SJ, Oliver G, Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. PLoS Biol. 2010;8(8) |
1 | J:217604 Lavado A, Ware M, Pare J, Cao X, The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Development. 2014 Nov;141(21):4182-93 |
1 | J:80913 Lee J, Wu Y, Qi Y, Xue H, Liu Y, Scheel D, German M, Qiu M, Guillemot F, Rao M, Neurogenin3 participates in gliogenesis in the developing vertebrate spinal cord. Dev Biol. 2003 Jan 1;253(1):84-98 |
1* | J:131173 Liu Y, El-Naggar S, Darling DS, Higashi Y, Dean DC, Zeb1 links epithelial-mesenchymal transition and cellular senescence. Development. 2008 Feb;135(3):579-88 |
1 | J:217046 Magnani D, Hasenpusch-Theil K, Benadiba C, Yu T, Basson MA, Price DJ, Lebrand C, Theil T, Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Cereb Cortex. 2014 Jan;24(1):186-98 |
1 | J:104532 Mendes SW, Henkemeyer M, Liebl DJ, Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J Neurosci. 2006 Jan 18;26(3):882-92 |
1 | J:198698 Meng L, Lin T, Peng G, Hsu JK, Lee S, Lin SY, Tsai RY, Nucleostemin deletion reveals an essential mechanism that maintains the genomic stability of stem and progenitor cells. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11415-20 |
1 | J:34807 Miyata T, Nakajima K, Aruga J, Takahashi S, Ikenaka K, Mikoshiba K, Ogawa M, Distribution of a reeler gene-related antigen in the developing cerebellum: an immunohistochemical study with an allogeneic antibody CR-50 on normal and reeler mice. J Comp Neurol. 1996 Aug 19;372(2):215-28 |
1 | J:341495 Mizukoshi T, Yamada S, Sakakibara SI, Spatiotemporal Regulation of De Novo and Salvage Purine Synthesis during Brain Development. eNeuro. 2023 Oct;10(10):ENEURO.0159-23.2023 |
1 | J:200905 Munoz DM, Singh S, Tung T, Agnihotri S, Nagy A, Guha A, Zadeh G, Hawkins C, Differential transformation capacity of neuro-glial progenitors during development. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14378-83 |
1 | J:272073 Nicola Z, Fabel K, Kempermann G, Development of the adult neurogenic niche in the hippocampus of mice. Front Neuroanat. 2015;9:53 |
1 | J:154587 Niquille M, Garel S, Mann F, Hornung JP, Otsmane B, Chevalley S, Parras C, Guillemot F, Gaspar P, Yanagawa Y, Lebrand C, Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C. PLoS Biol. 2009 Oct;7(10):e1000230 |
1 | J:242339 Ohayon D, Garces A, Joly W, Soukkarieh C, Takagi T, Sabourin JC, Agius E, Darling DS, De Santa Barbara P, Higashi Y, Stolt CC, Hugnot JP, Richardson WD, Carroll P, Pattyn A, Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Cell Rep. 2016 Nov 01;17(6):1473-1481 |
1 | J:131109 Ohkubo Y, Uchida AO, Shin D, Partanen J, Vaccarino FM, Fibroblast growth factor receptor 1 is required for the proliferation of hippocampal progenitor cells and for hippocampal growth in mouse. J Neurosci. 2004 Jul 7;24(27):6057-69 |
1 | J:300967 Pajovic S, Siddaway R, Bridge T, Sheth J, Rakopoulos P, Kim B, Ryall S, Agnihotri S, Phillips L, Yu M, Li C, Milos S, Patel P, Srikanthan D, Huang A, Hawkins C, Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer. Nat Commun. 2020 Dec 4;11(1):6216 |
1 | J:331057 Parichha A, Datta D, Suresh V, Chatterjee M, Holtzman MJ, Tole S, Dentate gyrus morphogenesis is regulated by beta-catenin function in hem-derived fimbrial glia. Development. 2022 Nov 1;149(21):dev200953 |
1 | J:246653 Park JC, Jeong WJ, Kim MY, Min D, Choi KY, Retinoic-acid-mediated HRas stabilization induces neuronal differentiation of neural stem cells during brain development. J Cell Sci. 2016 Aug 01;129(15):2997-3007 |
2 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:160038 Piper M, Moldrich RX, Lindwall C, Little E, Barry G, Mason S, Sunn N, Kurniawan ND, Gronostajski RM, Richards LJ, Multiple non-cell-autonomous defects underlie neocortical callosal dysgenesis in Nfib-deficient mice. Neural Dev. 2009;4:43 |
1 | J:236865 Ramesh V, Bayam E, Cernilogar FM, Bonapace IM, Schulze M, Riemenschneider MJ, Schotta G, Gotz M, Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration. Genes Dev. 2016 Oct 1;30(19):2199-2212 |
1 | J:124218 Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan YN, Rakic P, Sestan N, Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci. 2007 Jul;10(7):819-27 |
1 | J:313294 Raucci F, Tiong JD, Wray S, P75 nerve growth factor receptors modulate development of GnRH neurons and olfactory ensheating cells. Front Neurosci. 2013;7:262 |
1 | J:125330 Reis JL, Correia-Pinto J, Monteiro MP, Hutchins GM, In utero topographic analysis of astrocytes and neuronal cells in the spinal cord of mutant mice with myelomeningocele. J Neurosurg. 2007 Jun;106(6 Suppl):472-9 |
1 | J:98558 Rick M, Ramos Garrido SI, Herr C, Thal DR, Noegel AA, Clemen CS, Nuclear localization of Annexin A7 during murine brain development. BMC Neurosci. 2005 Apr 10;6(1):25 |
2 | J:205632 Saito A, Kanemoto S, Kawasaki N, Asada R, Iwamoto H, Oki M, Miyagi H, Izumi S, Sanosaka T, Nakashima K, Imaizumi K, Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun. 2012;3:967 |
1 | J:241756 Sanchez-Camacho C, Ortega JA, Ocana I, Alcantara S, Bovolenta P, Appropriate Bmp7 levels are required for the differentiation of midline guidepost cells involved in corpus callosum formation. Dev Neurobiol. 2011 May;71(5):337-50 |
2* | J:237213 Selvaraj P, Xiao L, Lee C, Murthy SR, Cawley NX, Lane M, Merchenthaler I, Ahn S, Loh YP, Neurotrophic Factor-alpha1: A Key Wnt-beta-Catenin Dependent Anti-Proliferation Factor and ERK-Sox9 Activated Inducer of Embryonic Neural Stem Cell Differentiation to Astrocytes in Neurodevelopment. Stem Cells. 2017 Mar;35(3):557-571 |
1 | J:241169 Stergiopoulos A, Politis PK, Nuclear receptor NR5A2 controls neural stem cell fate decisions during development. Nat Commun. 2016 Jul 22;7:12230 |
2 | J:275375 Sun S, Zhu XJ, Huang H, Guo W, Tang T, Xie B, Xu X, Zhang Z, Shen Y, Dai ZM, Qiu M, WNT signaling represses astrogliogenesis via Ngn2-dependent direct suppression of astrocyte gene expression. Glia. 2019 Jul;67(7):1333-1343 |
1* | J:104160 Tole S, Gutin G, Bhatnagar L, Remedios R, Hebert JM, Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev Biol. 2006 Jan 1;289(1):141-51 |
1* | J:184936 Unni DK, Piper M, Moldrich RX, Gobius I, Liu S, Fothergill T, Donahoo AL, Baisden JM, Cooper HM, Richards LJ, Multiple Slits regulate the development of midline glial populations and the corpus callosum. Dev Biol. 2012 May 1;365(1):36-49 |
1 | J:221658 Vithayathil J, Pucilowska J, Goodnough LH, Atit RP, Landreth GE, Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation. J Neurosci. 2015 Apr 29;35(17):6836-48 |
1 | J:308798 Wittmann MT, Katada S, Sock E, Kirchner P, Ekici AB, Wegner M, Nakashima K, Lie DC, Reis A, scRNA sequencing uncovers a TCF4-dependent transcription factor network regulating commissure development in mouse. Development. 2021 Jul 15;148(14):dev196022 |
1 | J:105927 Wu S, Wu Y, Capecchi MR, Motoneurons and oligodendrocytes are sequentially generated from neural stem cells but do not appear to share common lineage-restricted progenitors in vivo. Development. 2006 Feb;133(4):581-90 |
1 | J:285763 Xu M, Han X, Liu R, Li Y, Qi C, Yang Z, Zhao C, Gao J, PDK1 Deficit Impairs the Development of the Dentate Gyrus in Mice. Cereb Cortex. 2019 Mar 1;29(3):1185-1198 |
1 | J:152576 Ye F, Chen Y, Hoang T, Montgomery RL, Zhao XH, Bu H, Hu T, Taketo MM, van Es JH, Clevers H, Hsieh J, Bassel-Duby R, Olson EN, Lu QR, HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci. 2009 Jul;12(7):829-38 |
1 | J:224155 You L, Yan K, Zhou J, Zhao H, Bertos NR, Park M, Wang E, Yang XJ, The lysine acetyltransferase activator Brpf1 governs dentate gyrus development through neural stem cells and progenitors. PLoS Genet. 2015 Mar;11(3):e1005034 |
1 | J:271709 Zheng C, Chen D, Zhang Y, Bai Y, Huang S, Zheng D, Liang W, She S, Peng X, Wang P, Mo X, Song Q, Lv P, Huang J, Ye RD, Wang Y, FAM19A1 is a new ligand for GPR1 that modulates neural stem-cell proliferation and differentiation. FASEB J. 2018 May 25;:fj201800020RRR |
1 | J:324298 Zhou J, Liu G, Zhang X, Wu C, Ma M, Wu J, Hou L, Yin B, Qiang B, Shu P, Peng X, Comparison of the Spatiotemporal Expression Patterns of Three Cre Lines, Emx1IRES-Cre, D6-Cre and hGFAP-Cre, Commonly Used in Neocortical Development Research. Cereb Cortex. 2022 Apr 5;32(8):1668-1681 |
Gfi1 growth factor independent 1 transcription repressor (Synonyms: Gfi-1, Pal-1, Pal1) | |
Results | Reference |
1 | J:98458 Kiernan AE, Pelling AL, Leung KK, Tang AS, Bell DM, Tease C, Lovell-Badge R, Steel KP, Cheah KS, Sox2 is required for sensory organ development in the mammalian inner ear. Nature. 2005 Apr 21;434(7036):1031-5 |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
2* | J:297267 Tang Q, Xu M, Xu J, Xie X, Yang H, Gan L, Gfi1-GCE inducible Cre line for hair cell-specific gene manipulation in mouse inner ear. Genesis. 2019 Sep;57(9):e23304 |
2* | J:80025 Wallis D, Hamblen M, Zhou Y, Venken KJ, Schumacher A, Grimes HL, Zoghbi HY, Orkin SH, Bellen HJ, The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival. Development. 2003 Jan;130(1):221-32 |
1* | J:160668 Yang H, Gan J, Xie X, Deng M, Feng L, Chen X, Gao Z, Gan L, Gfi1-Cre knock-in mouse line: A tool for inner ear hair cell-specific gene deletion. Genesis. 2010 Apr 13;48(6):400-406 |
Gfra1 glial cell line derived neurotrophic factor family receptor alpha 1 (Synonyms: GDNFR-alpha, GFR alpha-1) | |
Results | Reference |
1 | J:64589 Baudet C, Mikaels A, Westphal H, Johansen J, Johansen TE, Ernfors P, Positive and negative interactions of GDNF, NTN and ART in developing sensory neuron subpopulations, and their collaboration with neurotrophins. Development. 2000 Oct;127(20):4335-44 |
1 | J:44407 Luukko K, Suvanto P, Saarma M, Thesleff I, Expression of GDNF and its receptors in developing tooth is developmentally regulated and suggests multiple roles in innervation and organogenesis. Dev Dyn. 1997 Dec;210(4):463-71 |
1* | J:57342 Nishino J, Mochida K, Ohfuji Y, Shimazaki T, Meno C, Ohishi S, Matsuda Y, Fujii H, Saijoh Y, Hamada H, GFR alpha3, a component of the artemin receptor, is required for migration and survival of the superior cervical ganglion. Neuron. 1999 Aug;23(4):725-36 |
1 | J:223235 Park HJ, Bolton EC, Glial cell line-derived neurotrophic factor induces cell proliferation in the mouse urogenital sinus. Mol Endocrinol. 2015 Feb;29(2):289-306 |
1 | J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34 |
1* | J:241573 Pui HP, Saga Y, Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling. Mech Dev. 2017 Apr;144(Pt B):125-139 |
1* | J:258304 Pui HP, Saga Y, NANOS2 acts as an intrinsic regulator of gonocytes-to-spermatogonia transition in the murine testes. Mech Dev. 2018 Feb;149:27-40 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:202753 Uesaka T, Nagashimada M, Enomoto H, GDNF signaling levels control migration and neuronal differentiation of enteric ganglion precursors. J Neurosci. 2013 Oct 9;33(41):16372-82 |
1 | J:224366 Uesaka T, Nagashimada M, Enomoto H, Neuronal Differentiation in Schwann Cell Lineage Underlies Postnatal Neurogenesis in the Enteric Nervous System. J Neurosci. 2015 Jul 8;35(27):9879-88 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
Gfra2 glial cell line derived neurotrophic factor family receptor alpha 2 (Synonyms: GFR alpha 2, GFR alpha-2) | |
Results | Reference |
1 | J:64589 Baudet C, Mikaels A, Westphal H, Johansen J, Johansen TE, Ernfors P, Positive and negative interactions of GDNF, NTN and ART in developing sensory neuron subpopulations, and their collaboration with neurotrophins. Development. 2000 Oct;127(20):4335-44 |
1 | J:330742 Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM, In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022 Oct 17;132(20):e156955 |
1* | J:57342 Nishino J, Mochida K, Ohfuji Y, Shimazaki T, Meno C, Ohishi S, Matsuda Y, Fujii H, Saijoh Y, Hamada H, GFR alpha3, a component of the artemin receptor, is required for migration and survival of the superior cervical ganglion. Neuron. 1999 Aug;23(4):725-36 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
Gfra3 glial cell line derived neurotrophic factor family receptor alpha 3 (Synonyms: GFR alpha-3, GFRalpha3) | |
Results | Reference |
1 | J:64589 Baudet C, Mikaels A, Westphal H, Johansen J, Johansen TE, Ernfors P, Positive and negative interactions of GDNF, NTN and ART in developing sensory neuron subpopulations, and their collaboration with neurotrophins. Development. 2000 Oct;127(20):4335-44 |
1* | J:57342 Nishino J, Mochida K, Ohfuji Y, Shimazaki T, Meno C, Ohishi S, Matsuda Y, Fujii H, Saijoh Y, Hamada H, GFR alpha3, a component of the artemin receptor, is required for migration and survival of the superior cervical ganglion. Neuron. 1999 Aug;23(4):725-36 |
1 | J:290493 Peng YR, James RE, Yan W, Kay JN, Kolodkin AL, Sanes JR, Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch. Neuron. 2020 Feb 5;105(3):464-474.e6 |
Ggcx gamma-glutamyl carboxylase (Synonyms: vitamin K-dependent carboxylase) | |
Results | Reference |
2* | J:262230 Lacombe J, Rishavy MA, Berkner KL, Ferron M, VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo. JCI Insight. 2018 Jan 11;3(1) |
Ggps1 geranylgeranyl diphosphate synthase 1 (Synonyms: 1810026C22Rik, 9530089B04Rik, GGPPS, GGPP synthase) | |
Results | Reference |
1 | J:336898 Edwards W, Greco TM, Miner GE, Barker NK, Herring L, Cohen S, Cristea IM, Conlon FL, Quantitative proteomic profiling identifies global protein network dynamics in murine embryonic heart development. Dev Cell. 2023 Jun 19;58(12):1087-1105.e4 |
3 | J:233686 Jia WJ, Jiang S, Tang QL, Shen D, Xue B, Ning W, Li CJ, Geranylgeranyl Diphosphate Synthase Modulates Fetal Lung Branching Morphogenesis Possibly through Controlling K-Ras Prenylation. Am J Pathol. 2016 Jun;186(6):1454-65 |
Gh growth hormone | |
Results | Reference |
1 | J:223814 Aujla PK, Bogdanovic V, Naratadam GT, Raetzman LT, Persistent expression of activated notch in the developing hypothalamus affects survival of pituitary progenitors and alters pituitary structure. Dev Dyn. 2015 Aug;244(8):921-34 |
1 | J:193143 Bouchoucha YX, Charnay P, Gilardi-Hebenstreit P, Ablation of Egr2-positive cells in male mouse anterior pituitary leads to atypical isolated GH deficiency. Endocrinology. 2013 Jan;154(1):270-82 |
1* | J:290740 Brachet C, Kozhemyakina EA, Boros E, Heinrichs C, Balikova I, Soblet J, Smits G, Vilain C, Mathers PH, Truncating RAX Mutations: Anophthalmia, Hypopituitarism, Diabetes Insipidus, and Cleft Palate in Mice and Men. J Clin Endocrinol Metab. 2019 Jul 1;104(7):2925-2930 |
1 | J:236889 Cao D, Ma X, Cai J, Luan J, Liu AJ, Yang R, Cao Y, Zhu X, Zhang H, Chen YX, Shi Y, Shi GX, Zou D, Cao X, Grusby MJ, Xie Z, Zhang WJ, ZBTB20 is required for anterior pituitary development and lactotrope specification. Nat Commun. 2016 Apr 15;7:11121 |
1* | J:73085 Dasen JS, Barbera JP, Herman TS, Connell SO, Olson L, Ju B, Tollkuhn J, Baek SH, Rose DW, Rosenfeld MG, Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 1;15(23):3193-207 |
1 | J:70561 Dasen JS, O'Connell SM, Flynn SE, Treier M, Gleiberman AS, Szeto DP, Hooshmand F, Aggarwal AK, Rosenfeld MG, Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types. Cell. 1999 May 28;97(5):587-98 |
1 | J:235668 Goldsmith S, Lovell-Badge R, Rizzoti K, SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitary. Development. 2016 Jul 1;143(13):2376-88 |
1* | J:143548 Himes AD, Raetzman LT, Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1. Dev Biol. 2009 Jan 1;325(1):151-61 |
1* | J:19457 Japon MA, Rubinstein M, Low MJ, In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development. J Histochem Cytochem. 1994 Aug;42(8):1117-25 |
2 | J:240480 Kapali J, Kabat BE, Schmidt KL, Stallings CE, Tippy M, Jung DO, Edwards BS, Nantie LB, Raeztman LT, Navratil AM, Ellsworth BS, Foxo1 Is Required for Normal Somatotrope Differentiation. Endocrinology. 2016 Nov;157(11):4351-4363 |
1 | J:89087 Lamolet B, Poulin G, Chu K, Guillemot F, Tsai MJ, Drouin J, Tpit-independent function of NeuroD1(BETA2) in pituitary corticotroph differentiation. Mol Endocrinol. 2004 Apr;18(4):995-1003 |
1* | J:33102 Lin C, Lin SC, Chang CP, Rosenfeld MG, Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth [see comments]. Nature. 1992 Dec 24-31;360(6406):765-8 |
1* | J:35230 Nguyen AP, Chandorkar A, Gupta C, The role of growth hormone in fetal mouse reproductive tract differentiation. Endocrinology. 1996 Sep;137(9):3659-66 |
1* | J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20 |
1* | J:33050 Sheng HZ, Zhadanov AB, Mosinger B Jr, Fujii T, Bertuzzi S, Grinberg A, Lee EJ, Huang SP, Mahon KA, Westphal H, Specification of pituitary cell lineages by the LIM homeobox gene Lhx3. Science. 1996 May 17;272(5264):1004-7 |
1 | J:217081 Skowronska-Krawczyk D, Ma Q, Schwartz M, Scully K, Li W, Liu Z, Taylor H, Tollkuhn J, Ohgi KA, Notani D, Kohwi Y, Kohwi-Shigematsu T, Rosenfeld MG, Required enhancer-matrin-3 network interactions for a homeodomain transcription program. Nature. 2014 Oct 9;514(7521):257-61 |
1 | J:107205 Yevtodiyenko A, Schmidt JV, Dlk1 expression marks developing endothelium and sites of branching morphogenesis in the mouse embryo and placenta. Dev Dyn. 2006 Apr;235(4):1115-23 |
1 | J:112960 Zhu X, Zhang J, Tollkuhn J, Ohsawa R, Bresnick EH, Guillemot F, Kageyama R, Rosenfeld MG, Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. Genes Dev. 2006 Oct 1;20(19):2739-53 |
Ghr growth hormone receptor (Synonyms: GHBP, GHR/BP) | |
Results | Reference |
1* | J:22633 Ilkbahar YN, Wu K, Thordarson G, Talamantes F, Expression and distribution of messenger ribonucleic acids for growth hormone (GH) receptor and GH-binding protein in mice during pregnancy. Endocrinology. 1995 Feb;136(2):386-92 |
2* | J:26722 Southard JN, Barrett BA, Bikbulatova L, Ilkbahar Y, Wu K, Talamantes F, Growth hormone (GH) receptor and GH-binding protein messenger ribonucleic acids with alternative 5'-untranslated regions are differentially expressed in mouse liver and placenta. Endocrinology. 1995 Jul;136(7):2913-21 |
Ghrh growth hormone releasing hormone (Synonyms: Ghrf) | |
Results | Reference |
1 | J:240480 Kapali J, Kabat BE, Schmidt KL, Stallings CE, Tippy M, Jung DO, Edwards BS, Nantie LB, Raeztman LT, Navratil AM, Ellsworth BS, Foxo1 Is Required for Normal Somatotrope Differentiation. Endocrinology. 2016 Nov;157(11):4351-4363 |
1 | J:263715 Lee B, Kim J, An T, Kim S, Patel EM, Raber J, Lee SK, Lee S, Lee JW, Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons. Nat Commun. 2018 May 23;9(1):2026 |
Ghrhr growth hormone releasing hormone receptor (Synonyms: Ghrfr) | |
Results | Reference |
1 | J:240480 Kapali J, Kabat BE, Schmidt KL, Stallings CE, Tippy M, Jung DO, Edwards BS, Nantie LB, Raeztman LT, Navratil AM, Ellsworth BS, Foxo1 Is Required for Normal Somatotrope Differentiation. Endocrinology. 2016 Nov;157(11):4351-4363 |
1* | J:33102 Lin C, Lin SC, Chang CP, Rosenfeld MG, Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth [see comments]. Nature. 1992 Dec 24-31;360(6406):765-8 |
Ghrl ghrelin (Synonyms: 2210006E23Rik, Ghr, m46, MTLRP, MTLRPAP) | |
Results | Reference |
1* | J:175542 Anderson KR, Singer RA, Balderes DA, Hernandez-Lagunas L, Johnson CW, Artinger KB, Sussel L, The L6 domain tetraspanin Tm4sf4 regulates endocrine pancreas differentiation and directed cell migration. Development. 2011 Aug;138(15):3213-24 |
2 | J:156329 Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L, Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. J Biol Chem. 2009 Nov 6;284(45):31236-48 |
1 | J:129103 Chao CS, Loomis ZL, Lee JE, Sussel L, Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells. Dev Biol. 2007 Dec 15;312(2):523-32 |
2 | J:119914 Doyle MJ, Loomis ZL, Sussel L, Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet. Development. 2007 Feb;134(3):515-23 |
1 | J:176201 Kordowich S, Collombat P, Mansouri A, Serup P, Arx and Nkx2.2 compound deficiency redirects pancreatic alpha- and beta-cell differentiation to a somatostatin/ghrelin co-expressing cell lineage. BMC Dev Biol. 2011;11:52 |
1 | J:272578 Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G, Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. Dev Cell. 2019 Jan 7;48(1):49-63.e7 |
2 | J:290417 Lorberbaum DS, Kishore S, Rosselot C, Sarbaugh D, Brooks EP, Aragon E, Xuan S, Simon O, Ghosh D, Mendelsohn C, Gadue P, Sussel L, Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human beta cell specification. Development. 2020 Jun 22;147(12):dev189977 |
2 | J:88639 Prado CL, Pugh-Bernard AE, Elghazi L, Sosa-Pineda B, Sussel L, Ghrelin cells replace insulin-producing beta cells in two mouse models of pancreas development. Proc Natl Acad Sci U S A. 2004 Mar 2;101(9):2924-9 |
1 | J:147764 Svensson P, Bergqvist I, Norlin S, Edlund H, MFng is dispensable for mouse pancreas development and function. Mol Cell Biol. 2009 Apr;29(8):2129-38 |
Ghsr growth hormone secretagogue receptor (Synonyms: C530020I22Rik, Ghsr1a) | |
Results | Reference |
1* | J:308824 de Guia RM, Hassing AS, Ma T, Plucinska K, Holst B, Gerhart-Hines Z, Emanuelli B, Treebak JT, Ablation of Nampt in AgRP neurons leads to neurodegeneration and impairs fasting- and ghrelin-mediated food intake. FASEB J. 2021 May;35(5):e21450 |
Gigyf2 GRB10 interacting GYF protein 2 (Synonyms: 2610016F01Rik, A830080H02Rik, mKIAA0642, Tnrc15) | |
Results | Reference |
1* | J:353281 Rybiczka-Tesulov M, Garritsen O, Veno MT, Wieg L, Dijk RV, Rahimi K, Gomes-Duarte A, Wit M, van de Haar LL, Michels L, van Kronenburg NCH, van der Meer C, Kjems J, Vangoor VR, Pasterkamp RJ, Circular RNAs regulate neuron size and migration of midbrain dopamine neurons during development. Nat Commun. 2024 Aug 8;15(1):6773 |
Gip gastric inhibitory polypeptide (Synonyms: glucose-dependent insulinotropic polypeptide) | |
Results | Reference |
1 | J:119565 Boyer DF, Fujitani Y, Gannon M, Powers AC, Stein RW, Wright CV, Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression. Dev Biol. 2006 Oct 15;298(2):616-31 |
1* | J:191140 Grigoryan M, Kedees MH, Guz Y, Teitelman G, Phenotype of entero-endocrine L cells becomes restricted during development. Dev Dyn. 2012 Dec;241(12):1986-92 |
Gipc1 GIPC PDZ domain containing family, member 1 (Synonyms: Glut1CIP, neurophilin1-IP, Rgs19ip1, Semcap1, synectin, TaxIP2, TIP-2) | |
Results | Reference |
1* | J:94017 Zhang Y, Chittenden T, Simons M, Characterization of synectin expression and promoter activity. Gene. 2004 Nov 10;342(1):29-34 |
Gja1 gap junction protein, alpha 1 (Synonyms: alpha 1 connexin, Cnx43, connexin 43, connexin43, Cx43, Cx43alpha1, Gja-1) | |
Results | Reference |
1 | J:331266 Abou Nader N, Menard A, Levasseur A, St-Jean G, Boerboom D, Zamberlam G, Boyer A, Targeted Disruption of Lats1 and Lats2 in Mice Impairs Testis Development and Alters Somatic Cell Fate. Int J Mol Sci. 2022 Nov 5;23(21) |
2* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
1 | J:321578 Ang PS, Matrongolo MJ, Tischfield MA, The growth and expansion of meningeal lymphatic networks are affected in craniosynostosis. Development. 2022 Jan 1;149(1):dev200065 |
1 | J:149014 Bakker ML, Boukens BJ, Mommersteeg MT, Brons JF, Wakker V, Moorman AF, Christoffels VM, Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system. Circ Res. 2008 Jun 6;102(11):1340-9 |
1 | J:277168 Bohuslavova R, Cerychova R, Papousek F, Olejnickova V, Bartos M, Gorlach A, Kolar F, Sedmera D, Semenza GL, Pavlinkova G, HIF-1alpha is required for development of the sympathetic nervous system. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13414-13423 |
1 | J:131962 Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ, Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2111-6 |
1* | J:44410 Choudhry R, Pitts JD, Hodgins MB, Changing patterns of gap junctional intercellular communication and connexin distribution in mouse epidermis and hair follicles during embryonic development. Dev Dyn. 1997 Dec;210(4):417-30 |
1 | J:88394 Cohen-Salmon M, Maxeiner S, Kruger O, Theis M, Willecke K, Petit C, Expression of the connexin43- and connexin45-encoding genes in the developing and mature mouse inner ear. Cell Tissue Res. 2004 Apr;316(1):15-22 |
2* | J:24100 Dahl E, Winterhager E, Traub O, Willecke K, Expression of gap junction genes, connexin40 and connexin43, during fetal mouse development. Anat Embryol (Berl). 1995 Mar;191(3):267-78 |
1* | J:104850 Fushiki S, Perez Velazquez JL, Zhang L, Bechberger JF, Carlen PL, Naus CC, Changes in neuronal migration in neocortex of connexin43 null mutant mice. J Neuropathol Exp Neurol. 2003 Mar;62(3):304-14 |
1 | J:321161 Gerner L, Youssef G, O'Shaughnessy RF, The protein phosphatase 2A regulatory subunit Ppp2r2a is required for Connexin-43 dephosphorlyation during epidermal barrier acquisition. Exp Dermatol. 2013 Nov;22(11):754-6 |
1 | J:330742 Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM, In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022 Oct 17;132(20):e156955 |
1 | J:250657 Greulich F, Trowe MO, Leffler A, Stoetzer C, Farin HF, Kispert A, Misexpression of Tbx18 in cardiac chambers of fetal mice interferes with chamber-specific developmental programs but does not induce a pacemaker-like gene signature. J Mol Cell Cardiol. 2016 Aug;97:140-9 |
1 | J:173586 Hahurij ND, Kolditz DP, Bokenkamp R, Markwald RR, Schalij MJ, Poelmann RE, Gittenberger-DE Groot AC, Blom NA, Accessory atrioventricular myocardial pathways in mouse heart development: substrate for supraventricular tachycardias. Pediatr Res. 2011 Jul;70(1):37-43 |
2 | J:104324 Hirschy A, Schatzmann F, Ehler E, Perriard JC, Establishment of cardiac cytoarchitecture in the developing mouse heart. Dev Biol. 2006 Jan 15;289(2):430-41 |
1 | J:173649 Kanady JD, Dellinger MT, Munger SJ, Witte MH, Simon AM, Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax. Dev Biol. 2011 Jun 15;354(2):253-66 |
2 | J:112199 Le M, Li Z, Cilley RE, Donahue H, Chinoy MR, Connexin 43 gene expression in mice with cardiopulmonary developmental defects. Front Biosci. 2006;11:3014-25 |
2 | J:330697 Liu S, Lan Y, Zhao Y, Zhang Q, Lin T, Lin K, Guo J, Yan Y, Expression of connexin 43 protein in cardiomyocytes of heart failure mouse model. Front Cardiovasc Med. 2022;9:1028558 |
1 | J:341276 Matrongolo MJ, Ho-Nguyen KT, Jain M, Ang PS, Reddy A, Schaper S, Tischfield MA, Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice. Development. 2023 Sep 15;150(18):dev201381 |
1 | J:231667 Munger SJ, Geng X, Srinivasan RS, Witte MH, Paul DL, Simon AM, Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice. Dev Biol. 2016 Apr 15;412(2):173-90 |
1* | J:203768 Mustata RC, Vasile G, Fernandez-Vallone V, Strollo S, Lefort A, Libert F, Monteyne D, Perez-Morga D, Vassart G, Garcia MI, Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium. Cell Rep. 2013 Oct 31;5(2):421-32 |
1* | J:72502 Perez-Armendariz EM, Lamoyi E, Mason JI, Cisneros-Armas D, Luu-The V, Bravo Moreno JF, Developmental regulation of connexin 43 expression in fetal mouse testicular cells. Anat Rec. 2001 Nov 1;264(3):237-46 |
2* | J:82568 Perez-Armendariz EM, Saez JC, Bravo-Moreno JF, Lopez-Olmos V, Enders GC, Villalpando I, Connexin43 is expressed in mouse fetal ovary. Anat Rec A Discov Mol Cell Evol Biol. 2003 Apr;271(2):360-7 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
1 | J:122566 Simirskii VN, Wang Y, Duncan MK, Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype. Dev Biol. 2007 Jun 15;306(2):658-68 |
1* | J:93582 von Maltzahn J, Euwens C, Willecke K, Sohl G, The novel mouse connexin39 gene is expressed in developing striated muscle fibers. J Cell Sci. 2004 Oct 15;117(Pt 22):5381-92 |
1 | J:172698 von Maltzahn J, Wulf V, Matern G, Willecke K, Connexin39 deficient mice display accelerated myogenesis and regeneration of skeletal muscle. Exp Cell Res. 2011 May 1;317(8):1169-78 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:46473 Ya J, Erdtsieck-Ernste EB, de Boer PA, van Kempen MJ, Jongsma H , Gros D , Moorman AF , Lamers WH, Heart defects in connexin43-deficient mice. Circ Res. 1998 Feb 23;82(3):360-6 |
Gja3 gap junction protein, alpha 3 (Synonyms: alpha 3 connexin, connexin 46, Cx46, Gja-3) | |
Results | Reference |
1 | J:181527 Chaible LM, Sanches DS, Cogliati B, Mennecier G, Dagli ML, Delayed osteoblastic differentiation and bone development in Cx43 knockout mice. Toxicol Pathol. 2011 Dec;39(7):1046-55 |
1 | J:343554 Sun Q, Li J, Ma J, Zheng Y, Ju R, Li X, Ren X, Huang L, Chen R, Tan X, Luo L, JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development. Invest Ophthalmol Vis Sci. 2023 Dec 1;64(15):15 |
Gja4 gap junction protein, alpha 4 (Synonyms: Cnx37, connexin 37, Cx37, Gja-4) | |
Results | Reference |
1 | J:228882 Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS, Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016 Jan 1;409(1):218-33 |
3* | J:62767 Haefliger JA, Polikar R, Schnyder G, Burdet M, Sutter E, Pexieder T, Nicod P, Meda P, Connexin37 in normal and pathological development of mouse heart and great arteries. Dev Dyn. 2000 Jun;218(2):331-44 |
1 | J:173649 Kanady JD, Dellinger MT, Munger SJ, Witte MH, Simon AM, Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax. Dev Biol. 2011 Jun 15;354(2):253-66 |
1 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
1 | J:231667 Munger SJ, Geng X, Srinivasan RS, Witte MH, Paul DL, Simon AM, Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice. Dev Biol. 2016 Apr 15;412(2):173-90 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
Gja5 gap junction protein, alpha 5 (Synonyms: connexin 40, Cx40, Gja-5) | |
Results | Reference |
1 | J:149014 Bakker ML, Boukens BJ, Mommersteeg MT, Brons JF, Wakker V, Moorman AF, Christoffels VM, Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system. Circ Res. 2008 Jun 6;102(11):1340-9 |
1 | J:131962 Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ, Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2111-6 |
1 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1* | J:264603 Da Silva F, Massa F, Motamedi FJ, Vidal V, Rocha AS, Gregoire EP, Cai CL, Wagner KD, Schedl A, Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4. Dev Biol. 2018 Sep 1;441(1):42-51 |
2* | J:24100 Dahl E, Winterhager E, Traub O, Willecke K, Expression of gap junction genes, connexin40 and connexin43, during fetal mouse development. Anat Embryol (Berl). 1995 Mar;191(3):267-78 |
1 | J:211437 de la Rosa AJ, Dominguez JN, Sedmera D, Sankova B, Hove-Madsen L, Franco D, Aranega AE, Functional suppression of Kcnq1 leads to early sodium channel remodelling and cardiac conduction system dysmorphogenesis. Cardiovasc Res. 2013 Jun 1;98(3):504-14 |
1 | J:308786 Delgado C, Bu L, Zhang J, Liu FY, Sall J, Liang FX, Furley AJ, Fishman GI, Neural cell adhesion molecule is required for ventricular conduction system development. Development. 2021 Jun 1;148(11):dev199431 |
1 | J:119145 Franco D, Meilhac SM, Christoffels VM, Kispert A, Buckingham M, Kelly RG, Left and right ventricular contributions to the formation of the interventricular septum in the mouse heart. Dev Biol. 2006 Jun 15;294(2):366-75 |
1 | J:355142 Gomez-Del Arco P, Isern J, Jimenez-Carretero D, Lopez-Maderuelo D, Pineiro-Sabaris R, El Abdellaoui-Soussi F, Torroja C, Vera-Pedrosa ML, Grima-Terren M, Benguria A, Simon-Chica A, Queiro-Palou A, Dopazo A, Sanchez-Cabo F, Jalife J, de la Pompa JL, Filgueiras-Rama D, Munoz-Canoves P, Redondo JM, The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development. Nat Commun. 2024 Oct 4;15(1):8602 |
1 | J:330742 Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM, In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022 Oct 17;132(20):e156955 |
1* | J:306155 Goodyer WR, Beyersdorf BM, Paik DT, Tian L, Li G, Buikema JW, Chirikian O, Choi S, Venkatraman S, Adams EL, Tessier-Lavigne M, Wu JC, Wu SM, Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution. Circ Res. 2019 Aug 2;125(4):379-397 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
1 | J:250657 Greulich F, Trowe MO, Leffler A, Stoetzer C, Farin HF, Kispert A, Misexpression of Tbx18 in cardiac chambers of fetal mice interferes with chamber-specific developmental programs but does not induce a pacemaker-like gene signature. J Mol Cell Cardiol. 2016 Aug;97:140-9 |
1 | J:204126 Liang X, Wang G, Lin L, Lowe J, Zhang Q, Bu L, Chen Y, Chen J, Sun Y, Evans SM, HCN4 dynamically marks the first heart field and conduction system precursors. Circ Res. 2013 Aug 2;113(4):399-407 |
2 | J:316536 Lubkemeier I, Andrie R, Lickfett L, Bosen F, Stockigt F, Dobrowolski R, Draffehn AM, Fregeac J, Schultze JL, Bukauskas FF, Schrickel JW, Willecke K, The Connexin40A96S mutation from a patient with atrial fibrillation causes decreased atrial conduction velocities and sustained episodes of induced atrial fibrillation in mice. J Mol Cell Cardiol. 2013 Dec;65:19-32 |
1 | J:306259 Luo W, Garcia-Gonzalez I, Fernandez-Chacon M, Casquero-Garcia V, Sanchez-Munoz MS, Muhleder S, Garcia-Ortega L, Andrade J, Potente M, Benedito R, Arterialization requires the timely suppression of cell growth. Nature. 2021 Jan;589(7842):437-441 |
1 | J:141338 Mommersteeg MT, Brown NA, Prall OW, de Gier-de Vries C, Harvey RP, Moorman AF, Christoffels VM, Pitx2c and Nkx2-5 are required for the formation and identity of the pulmonary myocardium. Circ Res. 2007 Oct 26;101(9):902-9 |
1 | J:262023 Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K, Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling. Circ Res. 2017 Apr 14;120(8):1276-1288 |
1 | J:269446 Salguero-Jimenez A, Grego-Bessa J, D'Amato G, Jimenez-Borreguero LJ, de la Pompa JL, Myocardial Notch1-Rbpj deletion does not affect NOTCH signaling, heart development or function. PLoS One. 2018;13(12):e0203100 |
1 | J:202658 Sankova B, Benes J Jr, Krejci E, Dupays L, Theveniau-Ruissy M, Miquerol L, Sedmera D, The effect of connexin40 deficiency on ventricular conduction system function during development. Cardiovasc Res. 2012 Sep 1;95(4):469-79 |
1 | J:151368 Theveniau-Ruissy M, Dandonneau M, Mesbah K, Ghez O, Mattei MG, Miquerol L, Kelly RG, The del22q11.2 candidate gene Tbx1 controls regional outflow tract identity and coronary artery patterning. Circ Res. 2008 Jul 18;103(2):142-8 |
1 | J:299728 Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL, Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. Elife. 2019 Dec 4;8:e49977 |
1* | J:93582 von Maltzahn J, Euwens C, Willecke K, Sohl G, The novel mouse connexin39 gene is expressed in developing striated muscle fibers. J Cell Sci. 2004 Oct 15;117(Pt 22):5381-92 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:46473 Ya J, Erdtsieck-Ernste EB, de Boer PA, van Kempen MJ, Jongsma H , Gros D , Moorman AF , Lamers WH, Heart defects in connexin43-deficient mice. Circ Res. 1998 Feb 23;82(3):360-6 |
Gja8 gap junction protein, alpha 8 (Synonyms: Aey5, alpha 8 connexin, Cnx50, connexin 50, Cx50, dcm, Lop10) | |
Results | Reference |
2 | J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134 |
1 | J:343554 Sun Q, Li J, Ma J, Zheng Y, Ju R, Li X, Ren X, Huang L, Chen R, Tan X, Luo L, JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development. Invest Ophthalmol Vis Sci. 2023 Dec 1;64(15):15 |
Gja10 gap junction protein, alpha 10 (Synonyms: connexin-57, Cx-57, Cx57, Cx59) | |
Results | Reference |
1 | J:90294 Hombach S, Janssen-Bienhold U, Sohl G, Schubert T, Bussow H, Ott T, Weiler R, Willecke K, Functional expression of connexin57 in horizontal cells of the mouse retina. Eur J Neurosci. 2004 May;19(10):2633-40 |
Gjb2 gap junction protein, beta 2 (Synonyms: connexin 26, Cx26, Gjb-2) | |
Results | Reference |
1* | J:44410 Choudhry R, Pitts JD, Hodgins MB, Changing patterns of gap junctional intercellular communication and connexin distribution in mouse epidermis and hair follicles during embryonic development. Dev Dyn. 1997 Dec;210(4):417-30 |
1 | J:108850 Djalilian AR, McGaughey D, Patel S, Seo EY, Yang C, Cheng J, Tomic M, Sinha S, Ishida-Yamamoto A, Segre JA, Connexin 26 regulates epidermal barrier and wound remodeling and promotes psoriasiform response. J Clin Invest. 2006 May;116(5):1243-53 |
1 | J:180242 Dupressoir A, Vernochet C, Harper F, Guegan J, Dessen P, Pierron G, Heidmann T, A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1164-73 |
1 | J:171693 Kim HM, Wangemann P, Epithelial cell stretching and luminal acidification lead to a retarded development of stria vascularis and deafness in mice lacking pendrin. PLoS One. 2011;6(3):e17949 |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Gjb3 gap junction protein, beta 3 (Synonyms: Cnx31, connexin 31, Cx31, D4Wsu144e, Gjb-3) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
Gjb6 gap junction protein, beta 6 (Synonyms: connexin 30, Cx30, D14Bwg0506e) | |
Results | Reference |
1 | J:180242 Dupressoir A, Vernochet C, Harper F, Guegan J, Dessen P, Pierron G, Heidmann T, A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1164-73 |
1 | J:193630 Fujimoto A, Kurban M, Nakamura M, Farooq M, Fujikawa H, Kibbi AG, Ito M, Dahdah M, Matta M, Diab H, Shimomura Y, GJB6, of which mutations underlie Clouston syndrome, is a potential direct target gene of p63. J Dermatol Sci. 2013 Feb;69(2):159-66 |
Gjc1 gap junction protein, gamma 1 (Synonyms: C130009G16Rik, connexin 45, Cx45, Gja-7, Gja7) | |
Results | Reference |
1 | J:181527 Chaible LM, Sanches DS, Cogliati B, Mennecier G, Dagli ML, Delayed osteoblastic differentiation and bone development in Cx43 knockout mice. Toxicol Pathol. 2011 Dec;39(7):1046-55 |
1 | J:131962 Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ, Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2111-6 |
1 | J:88394 Cohen-Salmon M, Maxeiner S, Kruger O, Theis M, Willecke K, Petit C, Expression of the connexin43- and connexin45-encoding genes in the developing and mature mouse inner ear. Cell Tissue Res. 2004 Apr;316(1):15-22 |
1 | J:46473 Ya J, Erdtsieck-Ernste EB, de Boer PA, van Kempen MJ, Jongsma H , Gros D , Moorman AF , Lamers WH, Heart defects in connexin43-deficient mice. Circ Res. 1998 Feb 23;82(3):360-6 |
Gjc2 gap junction protein, gamma 2 (Synonyms: B230382L12Rik, connexin 47, Cx47, Gja12) | |
Results | Reference |
1 | J:173649 Kanady JD, Dellinger MT, Munger SJ, Witte MH, Simon AM, Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax. Dev Biol. 2011 Jun 15;354(2):253-66 |
1 | J:231667 Munger SJ, Geng X, Srinivasan RS, Witte MH, Paul DL, Simon AM, Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice. Dev Biol. 2016 Apr 15;412(2):173-90 |
Gjd3 gap junction protein, delta 3 (Synonyms: connexin 30.2, connexin-30.2, cx30.2, Gja11, Gjc1) | |
Results | Reference |
1 | J:224301 Harris JP, Bhakta M, Bezprozvannaya S, Wang L, Lubczyk C, Olson EN, Munshi NV, MyoR modulates cardiac conduction by repressing Gata4. Mol Cell Biol. 2015 Feb;35(4):649-61 |
Gjd4 gap junction protein, delta 4 (Synonyms: 9430022F06Rik, connexin 39, Cx39) | |
Results | Reference |
4* | J:93582 von Maltzahn J, Euwens C, Willecke K, Sohl G, The novel mouse connexin39 gene is expressed in developing striated muscle fibers. J Cell Sci. 2004 Oct 15;117(Pt 22):5381-92 |
1 | J:172698 von Maltzahn J, Wulf V, Matern G, Willecke K, Connexin39 deficient mice display accelerated myogenesis and regeneration of skeletal muscle. Exp Cell Res. 2011 May 1;317(8):1169-78 |
Glb1 galactosidase, beta 1 (Synonyms: Bge, Bgl, Bgl-e, Bgl-s, Bgl-t, Bgs, Bgt, C130097A14Rik) | |
Results | Reference |
1 | J:177806 Cho J, Shen H, Yu H, Li H, Cheng T, Lee SB, Lee BC, Ewing sarcoma gene Ews regulates hematopoietic stem cell senescence. Blood. 2011 Jan 27;117(4):1156-66 |
1 | J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90 |
1 | J:255932 Mario Gonzalez-Meljem J, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Neda Mousavy-Gharavy S, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Pedro Martinez-Barbera J, Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. Nat Commun. 2017 Nov 28;8(1):1819 |
Glcci1 glucocorticoid induced transcript 1 (Synonyms: 2310047L21Rik, A130036A18Rik, Fam117c, GIG18, Tssn1) | |
Results | Reference |
2* | J:252114 Kohli V, Nardini D, Ehrman LA, Waclaw RR, Characterization of Glcci1 expression in a subpopulation of lateral ganglionic eminence progenitors in the mouse telencephalon. Dev Dyn. 2018 Jan;247(1):222-228 |
Glce glucuronyl C5-epimerase (Synonyms: 1110017N23Rik, C130034A12Rik, heparan sulfate-glucuronic acid C5-epimerase, Hsepi) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Gldn gliomedin (Synonyms: CRG-L2, Crlg2) | |
Results | Reference |
1 | J:327415 Jing J, Feng J, Yuan Y, Guo T, Lei J, Pei F, Ho TV, Chai Y, Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022 Aug 16;13(1):4803 |
Glg1 golgi apparatus protein 1 (Synonyms: CFR, CFR-1, ESL-1, MG-160, MG160, Selel) | |
Results | Reference |
1* | J:28191 Antony C, Huchet M, Changeux JP, Cartaud J, Developmental regulation of membrane traffic organization during synaptogenesis in mouse diaphragm muscle. J Cell Biol. 1995 Aug;130(4):959-68 |
1 | J:163721 Yang T, Mendoza-Londono R, Lu H, Tao J, Li K, Keller B, Jiang MM, Shah R, Chen Y, Bertin TK, Engin F, Dabovic B, Rifkin DB, Hicks J, Jamrich M, Beaudet AL, Lee B, E-selectin ligand-1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-beta. J Clin Invest. 2010 Jul 1;120(7):2474-85 |
Gli1 GLI-Kruppel family member GLI1 (Synonyms: Zfp-5, Zfp5) | |
Results | Reference |
1 | J:346119 Amano K, Okuzaki D, Kitaoka Y, Kato S, Fujiwara M, Tanaka S, Iida S, Pth1r in Neural Crest Cells Regulates Nasal Cartilage Differentiation. J Dent Res. 2024 Mar;103(3):308-317 |
1 | J:307093 Amato CM, Yao HH, Developmental and sexual dimorphic atlas of the prenatal mouse external genitalia at the single-cell level. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2103856118 |
1 | J:337598 Au TYK, Yip RKH, Wynn SL, Tan TY, Fu A, Geng YH, Szeto IYY, Niu B, Yip KY, Cheung MCH, Lovell-Badge R, Cheah KSE, Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog-Wnt signaling, causing campomelia. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2208623119 |
1 | J:176604 Bell SM, Zhang L, Mendell A, Xu Y, Haitchi HM, Lessard JL, Whitsett JA, Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. Dev Biol. 2011 Oct 1;358(1):79-90 |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1* | J:168038 Bimonte S, De Angelis A, Quagliata L, Giusti F, Tammaro R, Dallai R, Ascenzi MG, Diez-Roux G, Franco B, Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol. 2011 Jan 15;349(2):179-91 |
1 | J:188176 Caparros-Martin JA, Valencia M, Reytor E, Pacheco M, Fernandez M, Perez-Aytes A, Gean E, Lapunzina P, Peters H, Goodship JA, Ruiz-Perez VL, The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia. Hum Mol Genet. 2013 Jan 1;22(1):124-39 |
1 | J:135168 Capurro MI, Xu P, Shi W, Li F, Jia A, Filmus J, Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding. Dev Cell. 2008 May;14(5):700-11 |
3 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1* | J:150375 Cobourne MT, Xavier GM, Depew M, Hagan L, Sealby J, Webster Z, Sharpe PT, Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome. Dev Biol. 2009 Jul 1;331(1):38-49 |
1 | J:111051 Cui CY, Hashimoto T, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9142-7 |
1 | J:317276 Dittmann K, Wuelling M, Uhmann A, Dullin C, Hahn H, Schweyer S, Vortkamp A, Wienands J, Inactivation of patched1 in murine chondrocytes causes spinal fusion without inflammation. Arthritis Rheumatol. 2014 Apr;66(4):831-40 |
1 | J:160493 Dy P, Smits P, Silvester A, Penzo-Mendez A, Dumitriu B, Han Y, de la Motte CA, Kingsley DM, Lefebvre V, Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. Dev Biol. 2010 May 15;341(2):346-59 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1* | J:42454 Grindley JC, Bellusci S, Perkins D, Hogan BL, Evidence for the involvement of the Gli gene family in embryonic mouse lung development. Dev Biol. 1997 Aug 15;188(2):337-48 |
1 | J:237540 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R, The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development. 2016 Nov 15;143(22):4182-4192 |
1* | J:231595 Gurdziel K, Vogt KR, Walton KD, Schneider GK, Gumucio DL, Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. Dev Dyn. 2016 May;245(5):614-26 |
1 | J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132 |
1 | J:175769 Hsu SH, Zhang X, Yu C, Li ZJ, Wunder JS, Hui CC, Alman BA, Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu. Development. 2011 Sep;138(17):3791-801 |
1 | J:152851 Huang X, Ketova T, Fleming JT, Wang H, Dey SK, Litingtung Y, Chiang C, Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus. Development. 2009 Aug;136(15):2535-43 |
2 | J:160335 Huang X, Liu J, Ketova T, Fleming JT, Grover VK, Cooper MK, Litingtung Y, Chiang C, Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8422-7 |
1* | J:17485 Hui CC, Slusarski D, Platt KA, Holmgren R, Joyner AL, Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development. Dev Biol. 1994 Apr;162(2):402-13 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
2* | J:280430 Janeckova E, Feng J, Li J, Rodriguez G, Chai Y, Dynamic activation of Wnt, Fgf, and Hh signaling during soft palate development. PLoS One. 2019;14(10):e0223879 |
1 | J:282774 Jia X, Min L, Zhu S, Zhang S, Huang X, Loss of sonic hedgehog gene leads to muscle development disorder and megaesophagus in mice. FASEB J. 2018 Oct;32(10):5703-5715 |
1 | J:260962 Kamiunten T, Ideno H, Shimada A, Arai Y, Terashima T, Tomooka Y, Nakamura Y, Nakashima K, Kimura H, Shinkai Y, Tachibana M, Nifuji A, Essential roles of G9a in cell proliferation and differentiation during tooth development. Exp Cell Res. 2017 Aug 15;357(2):202-210 |
1* | J:160585 Kesper DA, Didt-Koziel L, Vortkamp A, Gli2 activator function in preosteoblasts is sufficient to mediate Ihh-dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification. Dev Dyn. 2010 Jun;239(6):1818-26 |
2 | J:155826 King P, Paul A, Laufer E, Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21185-90 |
2 | J:151258 Kolterud A, Grosse AS, Zacharias WJ, Walton KD, Kretovich KE, Madison BB, Waghray M, Ferris JE, Hu C, Merchant JL, Dlugosz AA, Kottmann AH, Gumucio DL, Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning. Gastroenterology. 2009 Aug;137(2):618-28 |
1 | J:307764 Kothandapani A, Larsen MC, Lee J, Jorgensen JS, Jefcoate CR, Distinctive functioning of STARD1 in the fetal Leydig cells compared to adult Leydig and adrenal cells. Impact of Hedgehog signaling via the primary cilium. Mol Cell Endocrinol. 2021 Jul 1;531:111265 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1 | J:102948 Koziel L, Wuelling M, Schneider S, Vortkamp A, Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation. Development. 2005 Dec;132(23):5249-60 |
1 | J:147576 Kunisada M, Cui CY, Piao Y, Ko MS, Schlessinger D, Requirement for Shh and Fox family genes at different stages in sweat gland development. Hum Mol Genet. 2009 May 15;18(10):1769-78 |
1 | J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670 |
1 | J:78990 Lamm ML, Catbagan WS, Laciak RJ, Barnett DH, Hebner CM, Gaffield W, Walterhouse D, Iannaccone P, Bushman W, Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation. Dev Biol. 2002 Sep 15;249(2):349-66 |
2 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
1 | J:316483 Leek CC, Soulas JM, Bhattacharya I, Ganji E, Locke RC, Smith MC, Bhavsar JD, Polson SW, Ornitz DM, Killian ML, Deletion of Fibroblast growth factor 9 globally and in skeletal muscle results in enlarged tuberosities at sites of deltoid tendon attachments. Dev Dyn. 2021 Dec;250(12):1778-1795 |
2* | J:154372 Li X, Udager AM, Hu C, Qiao XT, Richards N, Gumucio DL, Dynamic patterning at the pylorus: Formation of an epithelial intestine-stomach boundary in late fetal life. Dev Dyn. 2009 Oct 29;238(12):3205-3217 |
2 | J:214993 Lin C, Chen MH, Yao E, Song H, Gacayan R, Hui CC, Chuang PT, Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development. Dev Biol. 2014 Aug 15;392(2):324-33 |
1 | J:237537 Liu C, Rodriguez K, Yao HH, Mapping lineage progression of somatic progenitor cells in the mouse fetal testis. Development. 2016 Oct 15;143(20):3700-3710 |
1 | J:348792 Mead TJ, Bhutada S, Foulcer SJ, Peruzzi N, Nelson CM, Seifert DE, Larkin J, Tran-Lundmark K, Filmus J, Apte SS, Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development. Matrix Biol. 2024 May 13; |
1 | J:205339 Mis EK, Liem KF Jr, Kong Y, Schwartz NB, Domowicz M, Weatherbee SD, Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length. Dev Biol. 2014 Jan 1;385(1):67-82 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1 | J:144348 Ohazama A, Johnson EB, Ota MS, Choi HJ, Porntaveetus T, Oommen S, Itoh N, Eto K, Gritli-Linde A, Herz J, Sharpe PT, Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One. 2008;3(12):e4092 |
2 | J:183783 Ortega MC, Cases O, Merchan P, Kozyraki R, Clemente D, de Castro F, Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development. Glia. 2012 May;60(6):851-66 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1 | J:179464 Paul A, Laufer E, Endogenous biotin as a marker of adrenocortical cells with steroidogenic potential. Mol Cell Endocrinol. 2011 Apr 10;336(1-2):133-40 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1 | J:335097 Qin T, Ho CC, Wang B, Hui CC, Sham MH, Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2206571119 |
1 | J:177268 Radzikinas K, Aven L, Jiang Z, Tran T, Paez-Cortez J, Boppidi K, Lu J, Fine A, Ai X, A Shh/miR-206/BDNF Cascade Coordinates Innervation and Formation of Airway Smooth Muscle. J Neurosci. 2011 Oct 26;31(43):15407-15 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1 | J:266746 Rudkouskaya A, Welch I, Dagnino L, ILK modulates epithelial polarity and matrix formation in hair follicles. Mol Biol Cell. 2014 Mar;25(5):620-32 |
1 | J:124105 Ruiz-Perez VL, Blair HJ, Rodriguez-Andres ME, Blanco MJ, Wilson A, Liu YN, Miles C, Peters H, Goodship JA, Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. Development. 2007 Aug;134(16):2903-12 |
1* | J:267242 Shi X, Zhang Z, Zhan X, Cao M, Satoh T, Akira S, Shpargel K, Magnuson T, Li Q, Wang R, Wang C, Ge K, Wu J, An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth. Nat Commun. 2014 Nov 5;5:5425 |
1 | J:290878 Sun X, Are A, Annusver K, Sivan U, Jacob T, Dalessandri T, Joost S, Fullgrabe A, Gerling M, Kasper M, Coordinated hedgehog signaling induces new hair follicles in adult skin. Elife. 2020 Mar 17;9:e46756 |
1 | J:160518 Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, Jenkins RB, Tihan T, Vandenberg SR, James CD, Tanaka K, Taylor MD, Weiss WA, Chesler L, Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010 May 15;24(10):1059-72 |
1* | J:113421 Szczepny A, Hime GR, Loveland KL, Expression of hedgehog signalling components in adult mouse testis. Dev Dyn. 2006 Nov;235(11):3063-70 |
1* | J:269344 Teng CS, Ting MC, Farmer DT, Brockop M, Maxson RE, Crump JG, Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome. Elife. 2018 Oct 25;7:e37024 |
1 | J:324690 Wang H, Zheng C, Lu W, He T, Fan J, Wang C, Jie Q, Chan D, Cheah KSE, Yang L, Hedgehog signaling orchestrates cartilage-to-bone transition independently of Smoothened. Matrix Biol. 2022 Apr 23; |
1* | J:154906 Wang W, Lian N, Li L, Moss HE, Wang W, Perrien DS, Elefteriou F, Yang X, Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription. Development. 2009 Dec;136(24):4143-53 |
1 | J:270427 Yabut OR, Fernandez G, Huynh T, Yoon K, Pleasure SJ, Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis. Cell Rep. 2015 Sep 29;12(12):2021-34 |
1 | J:282462 Yabut OR, Ng HX, Fernandez G, Yoon K, Kuhn J, Pleasure SJ, Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors. J Dev Biol. 2016 Dec;4(4) |
1 | J:320691 Yadav VK, Berger JM, Singh P, Nagarajan P, Karsenty G, Embryonic osteocalcin signaling determines lifelong adrenal steroidogenesis and homeostasis in the mouse. J Clin Invest. 2022 Feb 15;132(4):e153752 |
1 | J:360708 Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K, Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase. Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2320070121 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
Gli2 GLI-Kruppel family member GLI2 | |
Results | Reference |
1 | J:176604 Bell SM, Zhang L, Mendell A, Xu Y, Haitchi HM, Lessard JL, Whitsett JA, Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. Dev Biol. 2011 Oct 1;358(1):79-90 |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1 | J:173367 Ezratty EJ, Stokes N, Chai S, Shah AS, Williams SE, Fuchs E, A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development. Cell. 2011 Jun 24;145(7):1129-41 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1* | J:42454 Grindley JC, Bellusci S, Perkins D, Hogan BL, Evidence for the involvement of the Gli gene family in embryonic mouse lung development. Dev Biol. 1997 Aug 15;188(2):337-48 |
1 | J:112460 Hatsell SJ, Cowin P, Gli3-mediated repression of Hedgehog targets is required for normal mammary development. Development. 2006 Sep;133(18):3661-70 |
1* | J:17485 Hui CC, Slusarski D, Platt KA, Holmgren R, Joyner AL, Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development. Dev Biol. 1994 Apr;162(2):402-13 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1* | J:160585 Kesper DA, Didt-Koziel L, Vortkamp A, Gli2 activator function in preosteoblasts is sufficient to mediate Ihh-dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification. Dev Dyn. 2010 Jun;239(6):1818-26 |
1 | J:151258 Kolterud A, Grosse AS, Zacharias WJ, Walton KD, Kretovich KE, Madison BB, Waghray M, Ferris JE, Hu C, Merchant JL, Dlugosz AA, Kottmann AH, Gumucio DL, Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning. Gastroenterology. 2009 Aug;137(2):618-28 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1 | J:102948 Koziel L, Wuelling M, Schneider S, Vortkamp A, Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation. Development. 2005 Dec;132(23):5249-60 |
1 | J:78990 Lamm ML, Catbagan WS, Laciak RJ, Barnett DH, Hebner CM, Gaffield W, Walterhouse D, Iannaccone P, Bushman W, Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation. Dev Biol. 2002 Sep 15;249(2):349-66 |
2 | J:254469 Li J, Wang S, Anderson C, Zhao F, Qin Y, Wu D, Wu X, Liu J, He X, Zhao J, Zhang J, Requirement of Smad4 from Ocular Surface Ectoderm for Retinal Development. PLoS One. 2016;11(8):e0159639 |
1 | J:121301 Mau E, Whetstone H, Yu C, Hopyan S, Wunder JS, Alman BA, PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms. Dev Biol. 2007 May 1;305(1):28-39 |
1 | J:348792 Mead TJ, Bhutada S, Foulcer SJ, Peruzzi N, Nelson CM, Seifert DE, Larkin J, Tran-Lundmark K, Filmus J, Apte SS, Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development. Matrix Biol. 2024 May 13; |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1 | J:144348 Ohazama A, Johnson EB, Ota MS, Choi HJ, Porntaveetus T, Oommen S, Itoh N, Eto K, Gritli-Linde A, Herz J, Sharpe PT, Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One. 2008;3(12):e4092 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1 | J:335097 Qin T, Ho CC, Wang B, Hui CC, Sham MH, Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2206571119 |
1* | J:113421 Szczepny A, Hime GR, Loveland KL, Expression of hedgehog signalling components in adult mouse testis. Dev Dyn. 2006 Nov;235(11):3063-70 |
1 | J:270427 Yabut OR, Fernandez G, Huynh T, Yoon K, Pleasure SJ, Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis. Cell Rep. 2015 Sep 29;12(12):2021-34 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
Gli3 GLI-Kruppel family member GLI3 (Synonyms: Bph, brachyphalangy) | |
Results | Reference |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
1* | J:42454 Grindley JC, Bellusci S, Perkins D, Hogan BL, Evidence for the involvement of the Gli gene family in embryonic mouse lung development. Dev Biol. 1997 Aug 15;188(2):337-48 |
1* | J:48569 Grove EA, Tole S, Limon J, Yip L, Ragsdale CW, The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice. Development. 1998 Jun;125(12):2315-25 |
1* | J:17485 Hui CC, Slusarski D, Platt KA, Holmgren R, Joyner AL, Expression of three mouse homologs of the Drosophila segment polarity gene cubitus interruptus, Gli, Gli-2, and Gli-3, in ectoderm- and mesoderm-derived tissues suggests multiple roles during postimplantation development. Dev Biol. 1994 Apr;162(2):402-13 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:151258 Kolterud A, Grosse AS, Zacharias WJ, Walton KD, Kretovich KE, Madison BB, Waghray M, Ferris JE, Hu C, Merchant JL, Dlugosz AA, Kottmann AH, Gumucio DL, Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning. Gastroenterology. 2009 Aug;137(2):618-28 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1 | J:102948 Koziel L, Wuelling M, Schneider S, Vortkamp A, Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation. Development. 2005 Dec;132(23):5249-60 |
1 | J:78990 Lamm ML, Catbagan WS, Laciak RJ, Barnett DH, Hebner CM, Gaffield W, Walterhouse D, Iannaccone P, Bushman W, Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation. Dev Biol. 2002 Sep 15;249(2):349-66 |
2 | J:254469 Li J, Wang S, Anderson C, Zhao F, Qin Y, Wu D, Wu X, Liu J, He X, Zhao J, Zhang J, Requirement of Smad4 from Ocular Surface Ectoderm for Retinal Development. PLoS One. 2016;11(8):e0159639 |
1 | J:348857 Li Z, Liu G, Yang L, Sun M, Zhang Z, Xu Z, Gao Y, Jiang X, Su Z, Li X, Yang Z, BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period. Protein Cell. 2024 Jan 3;15(1):21-35 |
1 | J:121301 Mau E, Whetstone H, Yu C, Hopyan S, Wunder JS, Alman BA, PTHrP regulates growth plate chondrocyte differentiation and proliferation in a Gli3 dependent manner utilizing hedgehog ligand dependent and independent mechanisms. Dev Biol. 2007 May 1;305(1):28-39 |
1 | J:170582 Mundy C, Yasuda T, Kinumatsu T, Yamaguchi Y, Iwamoto M, Enomoto-Iwamoto M, Koyama E, Pacifici M, Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine. Dev Biol. 2011 Mar 1;351(1):70-81 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1 | J:163175 Rice DP, Connor EC, Veltmaat JM, Lana-Elola E, Veistinen L, Tanimoto Y, Bellusci S, Rice R, Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation. Hum Mol Genet. 2010 Sep 1;19(17):3457-67 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:113421 Szczepny A, Hime GR, Loveland KL, Expression of hedgehog signalling components in adult mouse testis. Dev Dyn. 2006 Nov;235(11):3063-70 |
1* | J:42036 Tribioli C, Frasch M, Lufkin T, Bapx1: an evolutionary conserved homologue of the Drosophila bagpipe homeobox gene is expressed in splanchnic mesoderm and the embryonic skeleton. Mech Dev. 1997 Jul;65(1-2):145-62 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1 | J:263202 Ungewitter EK, Rotgers E, Kang HS, Lichti-Kaiser K, Li L, Grimm SA, Jetten AM, Yao HH, Loss of Glis3 causes dysregulation of retrotransposon silencing and germ cell demise in fetal mouse testis. Sci Rep. 2018 Jun 25;8(1):9662 |
2 | J:171423 Wang H, Ge G, Uchida Y, Luu B, Ahn S, Gli3 is required for maintenance and fate specification of cortical progenitors. J Neurosci. 2011 Apr 27;31(17):6440-8 |
2 | J:149459 Wuelling M, Kaiser FJ, Buelens LA, Braunholz D, Shivdasani RA, Depping R, Vortkamp A, Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. Dev Biol. 2009 Apr 1;328(1):40-53 |
1 | J:283400 Wuelling M, Schneider S, Schrother VA, Waterkamp C, Hoffmann D, Vortkamp A, Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of chondrocyte hypertrophy. Dev Biol. 2020 Jan 1;457(1):104-118 |
1 | J:270427 Yabut OR, Fernandez G, Huynh T, Yoon K, Pleasure SJ, Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis. Cell Rep. 2015 Sep 29;12(12):2021-34 |
2 | J:282462 Yabut OR, Ng HX, Fernandez G, Yoon K, Kuhn J, Pleasure SJ, Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors. J Dev Biol. 2016 Dec;4(4) |
Glis1 GLIS family zinc finger 1 (Synonyms: GliH1) | |
Results | Reference |
1* | J:80052 Nakashima M, Tanese N, Ito M, Auerbach W, Bai C, Furukawa T, Toyono T, Akamine A, Joyner AL, A novel gene, GliH1, with homology to the Gli zinc finger domain not required for mouse development. Mech Dev. 2002 Nov;119(1):21 |
Glis3 GLIS family zinc finger 3 (Synonyms: 4833409N03Rik, E330013K21Rik) | |
Results | Reference |
1 | J:352715 Kang HS, Grimm SA, Liao XH, Jetten AM, GLIS3 expression in the thyroid gland in relation to TSH signaling and regulation of gene expression. Cell Mol Life Sci. 2024 Jan 28;81(1):65 |
1 | J:154990 Kang HS, Kim YS, ZeRuth G, Beak JY, Gerrish K, Kilic G, Sosa-Pineda B, Jensen J, Foley J, Jetten AM, Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression. Mol Cell Biol. 2009 Dec;29(24):6366-79 |
Glmn glomulin, FKBP associated protein (Synonyms: 9330160J16Rik, Fap48, Fap68) | |
Results | Reference |
1* | J:89176 McIntyre BA, Brouillard P, Aerts V, Gutierrez-Roelens I, Vikkula M, Glomulin is predominantly expressed in vascular smooth muscle cells in the embryonic and adult mouse. Gene Expr Patterns. 2004 May;4(3):351-8 |
Glra1 glycine receptor, alpha 1 subunit (Synonyms: B230397M16Rik, nmf11, oscillator, ot) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Glra2 glycine receptor, alpha 2 subunit | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Glra3 glycine receptor, alpha 3 subunit | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Glra4 glycine receptor, alpha 4 subunit | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Glrb glycine receptor, beta subunit | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Glrx glutaredoxin (Synonyms: D13Wsu156e, Grx1, TTase) | |
Results | Reference |
1 | J:74095 Kobayashi M, Nakamura H, Yodoi J, Shiota K, Immunohistochemical localization of thioredoxin and glutaredoxin in mouse embryos and fetuses. Antioxid Redox Signal. 2000 Winter;2(4):653-63 |
1 | J:74208 Kobayashi M, Nakamura H, Yodoi J, Shiota K, Ontogenesis of anti-oxidative enzymes in mouse embryos and fetuses: an immunohistochemical study. Ital J Anat Embryol. 2001;106(2 Suppl 2):137-42 |
Glrx2 glutaredoxin 2 (Synonyms: 1700010P22Rik, Grx2, thioltransferase) | |
Results | Reference |
1 | J:74095 Kobayashi M, Nakamura H, Yodoi J, Shiota K, Immunohistochemical localization of thioredoxin and glutaredoxin in mouse embryos and fetuses. Antioxid Redox Signal. 2000 Winter;2(4):653-63 |
1 | J:74208 Kobayashi M, Nakamura H, Yodoi J, Shiota K, Ontogenesis of anti-oxidative enzymes in mouse embryos and fetuses: an immunohistochemical study. Ital J Anat Embryol. 2001;106(2 Suppl 2):137-42 |
Glul glutamate-ammonia ligase (Synonyms: Glns, GS) | |
Results | Reference |
2* | J:262663 Burke ZD, Reed KR, Yeh SW, Meniel V, Sansom OJ, Clarke AR, Tosh D, Spatiotemporal regulation of liver development by the Wnt/beta-catenin pathway. Sci Rep. 2018 Feb 9;8(1):2735 |
1 | J:219427 Glasgow SM, Zhu W, Stolt CC, Huang TW, Chen F, LoTurco JJ, Neul JL, Wegner M, Mohila C, Deneen B, Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subtypes. Nat Neurosci. 2014 Oct;17(10):1322-9 |
1 | J:84301 Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M, The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 2003 Jul 1;17(13):1677-89 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1* | J:120114 Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY, A biphasic pattern of gene expression during mouse retina development. BMC Dev Biol. 2006;6:48 |
Gm2a GM2 ganglioside activator protein | |
Results | Reference |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Gm5165 predicted gene 5165 | |
Results | Reference |
1 | J:331893 Yang J, Zhang L, Li Y, Chen M, Identifying key m(6)A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses. Front Genet. 2022;13:974357 |
Gm10419 predicted gene 10419 | |
Results | Reference |
1* | J:331896 Huang J, Jiang B, Li GW, Zheng D, Li M, Xie X, Pan Y, Wei M, Liu X, Jiang X, Zhang X, Yang L, Bao L, Wang B, m(6)A-modified lincRNA Dubr is required for neuronal development by stabilizing YTHDF1/3 and facilitating mRNA translation. Cell Rep. 2022 Nov 22;41(8):111693 |
Gm10544 predicted gene 10544 | |
Results | Reference |
1 | J:331893 Yang J, Zhang L, Li Y, Chen M, Identifying key m(6)A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses. Front Genet. 2022;13:974357 |
Gm11837 predicted gene 11837 | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Gm12371 predicted gene 12371 | |
Results | Reference |
1* | J:331896 Huang J, Jiang B, Li GW, Zheng D, Li M, Xie X, Pan Y, Wei M, Liu X, Jiang X, Zhang X, Yang L, Bao L, Wang B, m(6)A-modified lincRNA Dubr is required for neuronal development by stabilizing YTHDF1/3 and facilitating mRNA translation. Cell Rep. 2022 Nov 22;41(8):111693 |
Gm12678 predicted gene 12678 | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Gm12680 predicted gene 12680 | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Gm12962 predicted gene 12962 (Synonyms: Gm2430) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Gm12999 predicted gene 12999 | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Gm13855 predicted gene 13855 | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Gm14014 predicted gene 14014 | |
Results | Reference |
1 | J:359854 Cano-Carrillo S, Garcia-Padilla C, Aranega AE, Lozano-Velasco E, Franco D, Mef2c- and Nkx2-5-Divergent Transcriptional Regulation of Chick WT1_76127 and Mouse Gm14014 lncRNAs and Their Implication in Epicardial Cell Migration. Int J Mol Sci. 2024 Nov 30;25(23) |
Gm14133 predicted gene 14133 | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Gm15318 predicted gene 15318 | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Gm16010 predicted gene 16010 | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Gm16163 predicted gene 16163 | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Gm16310 predicted gene 16310 | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Gm17102 predicted gene 17102 | |
Results | Reference |
1* | J:331896 Huang J, Jiang B, Li GW, Zheng D, Li M, Xie X, Pan Y, Wei M, Liu X, Jiang X, Zhang X, Yang L, Bao L, Wang B, m(6)A-modified lincRNA Dubr is required for neuronal development by stabilizing YTHDF1/3 and facilitating mRNA translation. Cell Rep. 2022 Nov 22;41(8):111693 |
Gm17501 predicted gene, 17501 | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Gm17750 predicted gene, 17750 | |
Results | Reference |
1* | J:225478 Oliver PL, Chodroff RA, Gosal A, Edwards B, Cheung AF, Gomez-Rodriguez J, Elliot G, Garrett LJ, Lickiss T, Szele F, Green ED, Molnar Z, Ponting CP, Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype. Cereb Cortex. 2015 Oct;25(10):3572-85 |
Gm19265 predicted gene, 19265 | |
Results | Reference |
1 | J:331893 Yang J, Zhang L, Li Y, Chen M, Identifying key m(6)A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses. Front Genet. 2022;13:974357 |
Gm19656 predicted gene, 19656 (Synonyms: Gm44653) | |
Results | Reference |
1* | J:330442 Garcia-Padilla C, Dominguez JN, Lodde V, Munk R, Abdelmohsen K, Gorospe M, Jimenez-Sabado V, Ginel A, Hove-Madsen L, Aranega AE, Franco D, Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation. FASEB J. 2022 Jan;36(1):e22051 |
Gm20634 predicted gene 20634 | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Gm26803 predicted gene, 26803 | |
Results | Reference |
1* | J:225478 Oliver PL, Chodroff RA, Gosal A, Edwards B, Cheung AF, Gomez-Rodriguez J, Elliot G, Garrett LJ, Lickiss T, Szele F, Green ED, Molnar Z, Ponting CP, Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype. Cereb Cortex. 2015 Oct;25(10):3572-85 |
Gm30731 predicted gene, 30731 (Synonyms: lnc-pou3f2, Pnky) | |
Results | Reference |
1* | J:224225 Ramos AD, Andersen RE, Liu SJ, Nowakowski TJ, Hong SJ, Gertz CC, Salinas RD, Zarabi H, Kriegstein AR, Lim DA, The long noncoding RNA Pnky regulates neuronal differentiation of embryonic and postnatal neural stem cells. Cell Stem Cell. 2015 Apr 2;16(4):439-47 |
Gm34220 predicted gene, 34220 (Synonyms: Linc-YY1) | |
Results | Reference |
1* | J:228292 Zhou L, Sun K, Zhao Y, Zhang S, Wang X, Li Y, Lu L, Chen X, Chen F, Bao X, Zhu X, Wang L, Tang LY, Esteban MA, Wang CC, Jauch R, Sun H, Wang H, Linc-YY1 promotes myogenic differentiation and muscle regeneration through an interaction with the transcription factor YY1. Nat Commun. 2015;6:10026 |
Gm38999 predicted gene, 38999 | |
Results | Reference |
2 | J:346376 Zoch A, Konieczny G, Auchynnikava T, Stallmeyer B, Rotte N, Heep M, Berrens RV, Schito M, Kabayama Y, Schopp T, Kliesch S, Houston B, Nagirnaja L, O'Bryan MK, Aston KI, Conrad DF, Rappsilber J, Allshire RC, Cook AG, Tuttelmann F, O'Carroll D, C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line. Mol Cell. 2024 Mar 21;84(6):1021-1035.e11 |
Gm43190 predicted gene 43190 | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Gm44934 predicted gene 44934 | |
Results | Reference |
1* | J:330442 Garcia-Padilla C, Dominguez JN, Lodde V, Munk R, Abdelmohsen K, Gorospe M, Jimenez-Sabado V, Ginel A, Hove-Madsen L, Aranega AE, Franco D, Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation. FASEB J. 2022 Jan;36(1):e22051 |
Gm45188 predicted gene 45188 | |
Results | Reference |
1* | J:330442 Garcia-Padilla C, Dominguez JN, Lodde V, Munk R, Abdelmohsen K, Gorospe M, Jimenez-Sabado V, Ginel A, Hove-Madsen L, Aranega AE, Franco D, Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation. FASEB J. 2022 Jan;36(1):e22051 |
Gmcl1 germ cell-less, spermatogenesis associated 1 (Synonyms: 2810049L19Rik, Btbd13, Gcl, mglc-1) | |
Results | Reference |
1* | J:61448 Leatherman JL, Kaestner KH, Jongens TA, Identification of a mouse germ cell-less homologue with conserved activity in Drosophila. Mech Dev. 2000 Apr;92(2):145-53 |
Gmip Gem-interacting protein (Synonyms: 5031419I10Rik) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Gmnc geminin coiled-coil domain containing (Synonyms: Gm606, LOC239789, LOC385639) | |
Results | Reference |
1* | J:310453 Kyrousi C, Arbi M, Pilz GA, Pefani DE, Lalioti ME, Ninkovic J, Gotz M, Lygerou Z, Taraviras S, Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche. Development. 2015 Nov 1;142(21):3661-74 |
Gmnn geminin (Synonyms: Gem) | |
Results | Reference |
1* | J:230806 Arbi M, Pefani DE, Kyrousi C, Lalioti ME, Kalogeropoulou A, Papanastasiou AD, Taraviras S, Lygerou Z, GemC1 controls multiciliogenesis in the airway epithelium. EMBO Rep. 2016 Mar;17(3):400-13 |
1 | J:171716 Schultz KM, Banisadr G, Lastra RO, McGuire T, Kessler JA, Miller RJ, McGarry TJ, Geminin-deficient neural stem cells exhibit normal cell division and normal neurogenesis. PLoS One. 2011;6(3):e17736 |
Gna12 guanine nucleotide binding protein, alpha 12 (Synonyms: Galpha12) | |
Results | Reference |
1* | J:235617 Xiang X, Li S, Zhuang X, Shi L, Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways. FEBS Lett. 2016 Sep;590(17):2940-55 |
Gna13 guanine nucleotide binding protein, alpha 13 (Synonyms: Galpha13) | |
Results | Reference |
1* | J:235617 Xiang X, Li S, Zhuang X, Shi L, Arhgef1 negatively regulates neurite outgrowth through activation of RhoA signaling pathways. FEBS Lett. 2016 Sep;590(17):2940-55 |
Gnai1 G protein subunit alpha i1 (Synonyms: Gialpha1) | |
Results | Reference |
1 | J:239974 Lacomme M, Tarchini B, Boudreau-Pinsonneault C, Monat C, Cayouette M, The LGN protein promotes planar proliferative divisions in the neocortex but apicobasal asymmetric terminal divisions in the retina. Development. 2016 Feb 15;143(4):575-81 |
Gnai2 G protein subunit alpha i2 (Synonyms: Galphai2, Gia, Gnai-2) | |
Results | Reference |
1 | J:174520 Enomoto T, Ohmoto M, Iwata T, Uno A, Saitou M, Yamaguchi T, Kominami R, Matsumoto I, Hirota J, Bcl11b/Ctip2 Controls the Differentiation of Vomeronasal Sensory Neurons in Mice. J Neurosci. 2011 Jul 13;31(28):10159-10173 |
1 | J:239974 Lacomme M, Tarchini B, Boudreau-Pinsonneault C, Monat C, Cayouette M, The LGN protein promotes planar proliferative divisions in the neocortex but apicobasal asymmetric terminal divisions in the retina. Development. 2016 Feb 15;143(4):575-81 |
Gnai3 G protein subunit alpha i3 (Synonyms: Galphai3) | |
Results | Reference |
1 | J:235730 Byrd KM, Lough KJ, Patel JH, Descovich CP, Curtis TA, Williams SE, LGN plays distinct roles in oral epithelial stratification, filiform papilla morphogenesis and hair follicle development. Development. 2016 Aug 1;143(15):2803-17 |
1 | J:201606 Ezan J, Lasvaux L, Gezer A, Novakovic A, May-Simera H, Belotti E, Lhoumeau AC, Birnbaumer L, Beer-Hammer S, Borg JP, Le Bivic A, Nurnberg B, Sans N, Montcouquiol M, Primary cilium migration depends on G-protein signalling control of subapical cytoskeleton. Nat Cell Biol. 2013 Sep;15(9):1107-15 |
1 | J:239974 Lacomme M, Tarchini B, Boudreau-Pinsonneault C, Monat C, Cayouette M, The LGN protein promotes planar proliferative divisions in the neocortex but apicobasal asymmetric terminal divisions in the retina. Development. 2016 Feb 15;143(4):575-81 |
1* | J:253585 Siletti K, Tarchini B, Hudspeth AJ, Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11170-E11179 |
1 | J:271898 Tadenev ALD, Akturk A, Devanney N, Mathur PD, Clark AM, Yang J, Tarchini B, GPSM2-GNAI Specifies the Tallest Stereocilia and Defines Hair Bundle Row Identity. Curr Biol. 2019 Feb 19; |
Gnal guanine nucleotide binding protein, alpha stimulating, olfactory type (Synonyms: 2610011C15Rik, 9630020G10Rik, G alpha 10, Galphaolf, Gna10, Golf) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Gnao1 guanine nucleotide binding protein, alpha O (Synonyms: alphaO, Galphao, GO, Go alpha) | |
Results | Reference |
2* | J:306185 Akamine S, Okuzono S, Yamamoto H, Setoyama D, Sagata N, Ohgidani M, Kato TA, Ishitani T, Kato H, Masuda K, Matsushita Y, Ono H, Ishizaki Y, Sanefuji M, Saitsu H, Matsumoto N, Kang D, Kanba S, Nakabeppu Y, Sakai Y, Ohga S, GNAO1 organizes the cytoskeletal remodeling and firing of developing neurons. FASEB J. 2020 Dec;34(12):16601-16621 |
1 | J:174520 Enomoto T, Ohmoto M, Iwata T, Uno A, Saitou M, Yamaguchi T, Kominami R, Matsumoto I, Hirota J, Bcl11b/Ctip2 Controls the Differentiation of Vomeronasal Sensory Neurons in Mice. J Neurosci. 2011 Jul 13;31(28):10159-10173 |
1 | J:239974 Lacomme M, Tarchini B, Boudreau-Pinsonneault C, Monat C, Cayouette M, The LGN protein promotes planar proliferative divisions in the neocortex but apicobasal asymmetric terminal divisions in the retina. Development. 2016 Feb 15;143(4):575-81 |
1 | J:154741 Prince JE, Cho JH, Dumontier E, Andrews W, Cutforth T, Tessier-Lavigne M, Parnavelas J, Cloutier JF, Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. J Neurosci. 2009 Nov 11;29(45):14211-22 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Gnas GNAS complex locus (Synonyms: G alpha s, Galphas, Gnas1, Gnasxl, Gsa, Gs alpha, Gs-alpha, Nesp, Nesp55, Nespl, neuroendocrine-specific Golgi protein p55 isoform 1, Oedsml, P1, P2, P3, SCG6, XLalphas) | |
Results | Reference |
2 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
1 | J:257079 Tafaj O, Hann S, Ayturk U, Warman ML, Juppner H, Mice maintain predominantly maternal Galphas expression throughout life in brown fat tissue (BAT), but not other tissues. Bone. 2017 Oct;103:177-187 |
1 | J:35446 Williamson CM, Schofield J, Dutton ER, Seymour A, Beechey CV , Edwards YH , Peters J, Glomerular-specific imprinting of the mouse gsalpha gene: how does this relate to hormone resistance in albright hereditary osteodystrophy?. Genomics. 1996 1;36(2):280-7 |
Gnat1 G protein subunit alpha transducin 1 (Synonyms: Gnat-1, Ird1, Ird2, irdr, Tralpha, transducin) | |
Results | Reference |
1 | J:285747 Liu S, Liu X, Li S, Huang X, Qian H, Jin K, Xiang M, Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5016-5027 |
Gnat2 G protein subunit alpha transducin 2 (Synonyms: Gnat-2, Gt-2, Tcalpha) | |
Results | Reference |
1 | J:223559 Goetz JJ, Martin GM, Chowdhury R, Trimarchi JM, Onecut1 and Onecut2 play critical roles in the development of the mouse retina. PLoS One. 2014;9(10):e110194 |
Gnat3 G protein subunit alpha transducin 3 (Synonyms: alpha-gustducin, Ggust, Gtn) | |
Results | Reference |
1 | J:186296 Saqui-Salces M, Keeley TM, Grosse AS, Qiao XT, El-Zaatari M, Gumucio DL, Samuelson LC, Merchant JL, Gastric tuft cells express DCLK1 and are expanded in hyperplasia. Histochem Cell Biol. 2011 Aug;136(2):191-204 |
Gnb1 guanine nucleotide binding protein (G protein), beta 1 | |
Results | Reference |
1* | J:242591 Guo Y, He X, Zhao L, Liu L, Song H, Wang X, Xu J, Ju X, Guo W, Zhu X, Gbeta2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex. Cereb Cortex. 2017 Jun 01;27(6):3414-3426 |
Gnb2 guanine nucleotide binding protein (G protein), beta 2 | |
Results | Reference |
2* | J:242591 Guo Y, He X, Zhao L, Liu L, Song H, Wang X, Xu J, Ju X, Guo W, Zhu X, Gbeta2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex. Cereb Cortex. 2017 Jun 01;27(6):3414-3426 |
Gnb3 guanine nucleotide binding protein (G protein), beta 3 | |
Results | Reference |
1 | J:223559 Goetz JJ, Martin GM, Chowdhury R, Trimarchi JM, Onecut1 and Onecut2 play critical roles in the development of the mouse retina. PLoS One. 2014;9(10):e110194 |
1* | J:242591 Guo Y, He X, Zhao L, Liu L, Song H, Wang X, Xu J, Ju X, Guo W, Zhu X, Gbeta2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex. Cereb Cortex. 2017 Jun 01;27(6):3414-3426 |
Gnb4 guanine nucleotide binding protein (G protein), beta 4 (Synonyms: 6720453A21Rik) | |
Results | Reference |
1* | J:242591 Guo Y, He X, Zhao L, Liu L, Song H, Wang X, Xu J, Ju X, Guo W, Zhu X, Gbeta2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex. Cereb Cortex. 2017 Jun 01;27(6):3414-3426 |
Gnb5 guanine nucleotide binding protein (G protein), beta 5 (Synonyms: G beta 5, Gbeta5) | |
Results | Reference |
1* | J:242591 Guo Y, He X, Zhao L, Liu L, Song H, Wang X, Xu J, Ju X, Guo W, Zhu X, Gbeta2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex. Cereb Cortex. 2017 Jun 01;27(6):3414-3426 |
Gng13 guanine nucleotide binding protein (G protein), gamma 13 (Synonyms: Ggamma13) | |
Results | Reference |
2* | J:122468 Fujino A, Pieretti-Vanmarcke R, Wong A, Donahoe PK, Arango NA, Sexual dimorphism of g-protein subunit Gng13 expression in the cortical region of the developing mouse ovary. Dev Dyn. 2007 Jul;236(7):1991-6 |
Gnl3 guanine nucleotide binding protein nucleolar 3 (Synonyms: NS, nucleostemin) | |
Results | Reference |
1* | J:117454 Meng L, Yasumoto H, Tsai RY, Multiple controls regulate nucleostemin partitioning between nucleolus and nucleoplasm. J Cell Sci. 2006 Dec 15;119(Pt 24):5124-36 |
1 | J:80512 Tsai RY, McKay RD, A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells. Genes Dev. 2002 Dec 1;16(23):2991-3003 |
Gnpda1 glucosamine-6-phosphate deaminase 1 (Synonyms: glucose-6-phosphate isomerase, Gnp1, Gnpi, oscillin) | |
Results | Reference |
1 | J:140565 Sakakura Y, Shibui T, Irie K, Yajima T, Metabolic mode peculiar to Meckel's cartilage: immunohistochemical comparisons of hypoxia-inducible factor-1alpha and glucose transporters in developing endochondral bones in mice. Eur J Oral Sci. 2008 Jul;116(4):341-52 |
Gnpnat1 glucosamine-phosphate N-acetyltransferase 1 (Synonyms: EMeg32) | |
Results | Reference |
1* | J:61767 Boehmelt G, Fialka I, Brothers G, McGinley MD, Patterson SD, Mo R, Hui CC, Chung S, Huber LA, Mak TW, Iscove NN, Cloning and characterization of the murine glucosamine-6-phosphate acetyltransferase EMeg32. Differential expression and intracellular membrane association. J Biol Chem. 2000 Apr 28;275(17):12821-32 |
Gnrh1 gonadotropin releasing hormone 1 (Synonyms: LHRH, LNRH) | |
Results | Reference |
1* | J:199435 Barraud P, St John JA, Stolt CC, Wegner M, Baker CV, Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Biol Open. 2013 Jul 15;2(7):750-9 |
1 | J:187456 Berghard A, Hagglund AC, Bohm S, Carlsson L, Lhx2-dependent specification of olfactory sensory neurons is required for successful integration of olfactory, vomeronasal, and GnRH neurons. FASEB J. 2012 Aug;26(8):3464-72 |
1* | J:161880 Bergman JE, Bosman EA, van Ravenswaaij-Arts CM, Steel KP, Study of smell and reproductive organs in a mouse model for CHARGE syndrome. Eur J Hum Genet. 2010 Feb;18(2):171-7 |
1 | J:187711 Cariboni A, Andrews WD, Memi F, Ypsilanti AR, Zelina P, Chedotal A, Parnavelas JG, Slit2 and Robo3 modulate the migration of GnRH-secreting neurons. Development. 2012 Sep;139(18):3326-31 |
1 | J:127370 Cogliati T, Delgado-Romero P, Norwitz ER, Guduric-Fuchs J, Kaiser UB, Wray S, Kirsch IR, Pubertal Impairment in Nhlh2 Null Mice Is Associated with Hypothalamic and Pituitary Deficiencies. Mol Endocrinol. 2007 Dec;21(12):3013-3027 |
1* | J:47986 Dellovade TL, Pfaff DW, Schwanzel-Fukuda M, The gonadotropin-releasing hormone system does not develop in Small-Eye (Sey) mouse phenotype. Brain Res Dev Brain Res. 1998 May 15;107(2):233-40 |
2 | J:99936 Givens ML, Rave-Harel N, Goonewardena VD, Kurotani R, Berdy SE, Swan CH, Rubenstein JL, Robert B, Mellon PL, Developmental regulation of gonadotropin-releasing hormone gene expression by the MSX and DLX homeodomain protein families. J Biol Chem. 2005 May 13;280(19):19156-65 |
1 | J:93303 Kruger M, Ruschke K, Braun T, NSCL-1 and NSCL-2 synergistically determine the fate of GnRH-1 neurons and control necdin gene expression. EMBO J. 2004 Nov 27;23(21):4353-64 |
1 | J:207602 Kumar D, Freese M, Drexler D, Hermans-Borgmeyer I, Marquardt A, Boehm U, Murine arcuate nucleus kisspeptin neurons communicate with GnRH neurons in utero. J Neurosci. 2014 Mar 5;34(10):3756-66 |
1 | J:226927 Kumar D, Periasamy V, Freese M, Voigt A, Boehm U, In Utero Development of Kisspeptin/GnRH Neural Circuitry in Male Mice. Endocrinology. 2015 Sep;156(9):3084-90 |
1 | J:237344 Lee B, Lee S, Lee SK, Lee JW, The LIM-homeobox transcription factor Isl1 plays crucial roles in the development of multiple arcuate nucleus neurons. Development. 2016 Oct 15;143(20):3763-3773 |
1 | J:308970 Mancini A, Howard SR, Marelli F, Cabrera CP, Barnes MR, Sternberg MJ, Leprovots M, Hadjidemetriou I, Monti E, David A, Wehkalampi K, Oleari R, Lettieri A, Vezzoli V, Vassart G, Cariboni A, Bonomi M, Garcia MI, Guasti L, Dunkel L, LGR4 deficiency results in delayed puberty through impaired Wnt/beta-catenin signaling. JCI Insight. 2020 Jun 4;5(11) |
1 | J:204198 Memi F, Abe P, Cariboni A, MacKay F, Parnavelas JG, Stumm R, CXC chemokine receptor 7 (CXCR7) affects the migration of GnRH neurons by regulating CXCL12 availability. J Neurosci. 2013 Oct 30;33(44):17527-37 |
1* | J:264529 Miller SR, Benito C, Mirsky R, Jessen KR, Baker CVH, Neural crest Notch/Rbpj signaling regulates olfactory gliogenesis and neuronal migration. Genesis. 2018 Jun;56(6-7):e23215 |
1* | J:20745 Naruse I, Fukui Y, Keino H, Taniguchi M, The arrest of luteinizing hormone-releasing hormone neuronal migration in the genetic arhinencephalic mouse embryo (Pdn/Pdn). Brain Res Dev Brain Res. 1994 Sep 16;81(2):178-84 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1* | J:127117 Pitteloud N, Zhang C, Pignatelli D, Li JD, Raivio T, Cole LW, Plummer L, Jacobson-Dickman EE, Mellon PL, Zhou QY, Crowley WF Jr, Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism. Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17447-52 |
1 | J:313294 Raucci F, Tiong JD, Wray S, P75 nerve growth factor receptors modulate development of GnRH neurons and olfactory ensheating cells. Front Neurosci. 2013;7:262 |
1* | J:268254 Rich CA, Perera SN, Andratschke J, Stolt CC, Buehler DP, Southard-Smith EM, Wegner M, Britsch S, Baker CVH, Olfactory ensheathing cells abutting the embryonic olfactory bulb express Frzb, whose deletion disrupts olfactory axon targeting. Glia. 2018 Dec;66(12):2617-2631 |
1 | J:299740 Schmid T, Boehm U, Braun T, GnRH neurogenesis depends on embryonic pheromone receptor expression. Mol Cell Endocrinol. 2020 Dec 1;518:111030 |
1* | J:68905 Simonian SX, Herbison AE, Regulation of gonadotropin-releasing hormone (GnRH) gene expression during GnRH neuron migration in the mouse. Neuroendocrinology. 2001 Mar;73(3):149-56 |
1* | J:193307 Wray S, Nieburgs A, Elkabes S, Spatiotemporal cell expression of luteinizing hormone-releasing hormone in the prenatal mouse: evidence for an embryonic origin in the olfactory placode. Brain Res Dev Brain Res. 1989 Apr 1;46(2):309-18 |
Gns glucosamine (N-acetyl)-6-sulfatase (Synonyms: 2610016K11Rik, G6S) | |
Results | Reference |
1* | J:160587 Ratzka A, Mundlos S, Vortkamp A, Expression patterns of sulfatase genes in the developing mouse embryo. Dev Dyn. 2010 Jun;239(6):1779-88 |
Golga2 golgin A2 (Synonyms: GM130) | |
Results | Reference |
1 | J:343556 Kretschmer V, Schneider S, Matthiessen PA, Reichert D, Hotaling N, Glassser G, Lieberwirth I, Bharti K, De Cegli R, Conte I, Nandrot EF, May-Simera HL, Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration. PLoS Biol. 2023 Dec;21(12):e3002402 |
1* | J:205338 Kuss P, Kraft K, Stumm J, Ibrahim D, Vallecillo-Garcia P, Mundlos S, Stricker S, Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A. Dev Biol. 2014 Jan 1;385(1):83-93 |
1 | J:205339 Mis EK, Liem KF Jr, Kong Y, Schwartz NB, Domowicz M, Weatherbee SD, Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length. Dev Biol. 2014 Jan 1;385(1):67-82 |
1 | J:232190 Noda K, Kitami M, Kitami K, Kaku M, Komatsu Y, Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development. Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2589-97 |
1 | J:253982 Norlin S, Parekh V, Edlund H, The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival. Development. 2018 Jan 3;145(1):dev154468 |
1 | J:191793 Schnatwinkel C, Niswander L, Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice. PLoS One. 2012;7(9):e44871 |
1 | J:206876 Song JY, Park R, Kim JY, Hughes L, Lu L, Kim S, Johnson RL, Cho SH, Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev Biol. 2014 Feb 15;386(2):281-90 |
Gorab golgin, RAB6-interacting (Synonyms: NTKL-BP1, Scyl1bp1) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Gpa33 glycoprotein A33 transmembrane (Synonyms: 2010310L10Rik, 2210401D16Rik, A33 antigen) | |
Results | Reference |
2* | J:65650 Abud HE, Johnstone CN, Tebbutt NC, Heath JK, The murine A33 antigen is expressed at two distinct sites during development, the ICM of the blastocyst and the intestinal epithelium. Mech Dev. 2000 Nov;98(1-2):111-4 |
2* | J:64884 Johnstone CN, Tebbutt NC, Abud HE, White SJ, Stenvers KL, Hall NE, Cody SH, Whitehead RH, Catimel B, Nice EC, Burgess AW, Heath JK, Characterization of mouse A33 antigen, a definitive marker for basolateral surfaces of intestinal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2000 Sep;279(3):G500-10 |
Gpank1 G patch domain and ankyrin repeats 1 (Synonyms: Bat4, D17H6S54E, G5) | |
Results | Reference |
1 | J:239479 Arora H, Boulberdaa M, Qureshi R, Bitirim V, Messadeq N, Dolle P, Nebigil CG, Prokineticin receptor 1 is required for mesenchymal-epithelial transition in kidney development. FASEB J. 2016 Aug;30(8):2733-40 |
Gpat2 glycerol-3-phosphate acyltransferase 2, mitochondrial (Synonyms: A530057A03Rik, Gpat2) | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
2* | J:277128 Shiromoto Y, Kuramochi-Miyagawa S, Nagamori I, Chuma S, Arakawa T, Nishimura T, Hasuwa H, Tachibana T, Ikawa M, Nakano T, GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice. Biol Reprod. 2019 Jul 1;101(1):248-256 |
Gpc1 glypican 1 | |
Results | Reference |
1 | J:83512 Hikake T, Mori T, Iseki K, Hagino S, Zhang Y, Takagi H, Yokoya S, Wanaka A, Comparison of expression patterns between CREB family transcription factor OASIS and proteoglycan core protein genes during murine tooth development. Anat Embryol (Berl). 2003 Apr;206(5):373-80 |
1* | J:45209 Litwack ED, Ivins JK, Kumbasar A, Paine-Saunders S, Stipp CS, Lander AD, Expression of the heparan sulfate proteoglycan glypican-1 in the developing rodent. Dev Dyn. 1998 Jan;211(1):72-87 |
1 | J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10) |
Gpc2 glypican 2 cerebroglycan (Synonyms: 2410016G05Rik) | |
Results | Reference |
1 | J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10) |
Gpc3 glypican 3 (Synonyms: OCI-5) | |
Results | Reference |
1* | J:67732 Grisaru S, Cano-Gauci D, Tee J, Filmus J, Rosenblum ND, Glypican-3 modulates BMP- and FGF-mediated effects during renal branching morphogenesis. Dev Biol. 2001 Mar 1;231(1):31-46 |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
1* | J:187541 Schievenbusch S, Sauer E, Curth HM, Schulte S, Demir M, Toex U, Goeser T, Nierhoff D, Neighbor of punc e 11: expression pattern of the new hepatic stem/progenitor cell marker during murine liver development. Stem Cells Dev. 2012 Sep 20;21(14):2656-66 |
1 | J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10) |
Gpc4 glypican 4 (Synonyms: 9530073D23Rik, K-glypican) | |
Results | Reference |
1 | J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10) |
Gpc5 glypican 5 (Synonyms: A230034F01Rik) | |
Results | Reference |
1* | J:45209 Litwack ED, Ivins JK, Kumbasar A, Paine-Saunders S, Stipp CS, Lander AD, Expression of the heparan sulfate proteoglycan glypican-1 in the developing rodent. Dev Dyn. 1998 Jan;211(1):72-87 |
1 | J:45283 Saunders S, Paine-Saunders S, Lander AD, Expression of the cell surface proteoglycan glypican-5 is developmentally regulated in kidney, limb, and brain. Dev Biol. 1997 Oct 1;190(1):78-93 |
1 | J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10) |
Gpc6 glypican 6 (Synonyms: 6720429C22Rik) | |
Results | Reference |
3 | J:348792 Mead TJ, Bhutada S, Foulcer SJ, Peruzzi N, Nelson CM, Seifert DE, Larkin J, Tran-Lundmark K, Filmus J, Apte SS, Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development. Matrix Biol. 2024 May 13; |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
1 | J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10) |
Gpm6a glycoprotein m6a (Synonyms: Gpm6, M6A) | |
Results | Reference |
1* | J:26641 Baumrind NL, Parkinson D, Wayne DB, Heuser JE, Pearlman AL, EMA: a developmentally regulated cell-surface glycoprotein of CNS neurons that is concentrated at the leading edge of growth cones. Dev Dyn. 1992 Aug;194(4):311-25 |
1 | J:236770 Mita S, de Monasterio-Schrader P, Funfschilling U, Kawasaki T, Mizuno H, Iwasato T, Nave KA, Werner HB, Hirata T, Transcallosal Projections Require Glycoprotein M6-Dependent Neurite Growth and Guidance. Cereb Cortex. 2015 Nov;25(11):4111-25 |
Gpm6b glycoprotein m6b (Synonyms: Gpm6, M6B) | |
Results | Reference |
1* | J:26641 Baumrind NL, Parkinson D, Wayne DB, Heuser JE, Pearlman AL, EMA: a developmentally regulated cell-surface glycoprotein of CNS neurons that is concentrated at the leading edge of growth cones. Dev Dyn. 1992 Aug;194(4):311-25 |
1 | J:236770 Mita S, de Monasterio-Schrader P, Funfschilling U, Kawasaki T, Mizuno H, Iwasato T, Nave KA, Werner HB, Hirata T, Transcallosal Projections Require Glycoprotein M6-Dependent Neurite Growth and Guidance. Cereb Cortex. 2015 Nov;25(11):4111-25 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Gpr6 G protein-coupled receptor 6 | |
Results | Reference |
2 | J:238868 Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z, The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 2016 Aug 02;16(5):1431-44 |
Gpr12 G-protein coupled receptor 12 (Synonyms: Gpcr01, Gpcr12, Gpcr20) | |
Results | Reference |
1* | J:81917 Ignatov A, Lintzel J, Hermans-Borgmeyer I, Kreienkamp HJ, Joost P, Thomsen S, Methner A, Schaller HC, Role of the G-protein-coupled receptor GPR12 as high-affinity receptor for sphingosylphosphorylcholine and its expression and function in brain development. J Neurosci. 2003 Feb 1;23(3):907-14 |
Gpr19 G protein-coupled receptor 19 | |
Results | Reference |
1 | J:94920 Hoffmeister-Ullerich SA, Susens U, Schaller HC, The orphan G-protein-coupled receptor GPR19 is expressed predominantly in neuronal cells during mouse embryogenesis. Cell Tissue Res. 2004 Nov;318(2):459-63 |
Gpr37l1 G protein-coupled receptor 37-like 1 (Synonyms: CAG-18, D0Kist8) | |
Results | Reference |
1* | J:237193 Chaboub LS, Manalo JM, Lee HK, Glasgow SM, Chen F, Kawasaki Y, Akiyama T, Kuo CT, Creighton CJ, Mohila CA, Deneen B, Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury. J Neurosci. 2016 Nov 23;36(47):11904-11917 |
Gpr50 G-protein-coupled receptor 50 (Synonyms: H9) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Gpr55 G protein-coupled receptor 55 (Synonyms: CTFL, LOC227326) | |
Results | Reference |
1 | J:171771 Wu CS, Zhu J, Wager-Miller J, Wang S, O'Leary D, Monory K, Lutz B, Mackie K, Lu HC, Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. Eur J Neurosci. 2010 Sep;32(5):693-706 |
Gpr85 G protein-coupled receptor 85 (Synonyms: 2900026B03Rik) | |
Results | Reference |
1* | J:119281 Hellebrand S, Wittenberger T, Schaller HC, Hermans-Borgmeyer I, Gpr85, a novel member of the G-protein coupled receptor family, prominently expressed in the developing mouse cerebral cortex. Brain Res Gene Expr Patterns. 2001 Aug;1(1):13-6 |
Gpr143 G protein-coupled receptor 143 (Synonyms: Oa1) | |
Results | Reference |
2* | J:65992 Surace EM, Angeletti B, Ballabio A, Marigo V, Expression pattern of the ocular albinism type 1 (Oa1) gene in the murine retinal pigment epithelium. Invest Ophthalmol Vis Sci. 2000 Dec;41(13):4333-7 |
Gpr149 G protein-coupled receptor 149 (Synonyms: 9630018L10Rik, Ieda, PGR10, R35) | |
Results | Reference |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Gpr151 G protein-coupled receptor 151 (Synonyms: C130082O03Rik, GalRL, PGR7) | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Gpr156 G protein-coupled receptor 156 (Synonyms: Gababl) | |
Results | Reference |
2 | J:306060 Kindt KS, Akturk A, Jarysta A, Day M, Beirl A, Flonard M, Tarchini B, EMX2-GPR156-Galphai reverses hair cell orientation in mechanosensory epithelia. Nat Commun. 2021 May 17;12(1):2861 |
Gprasp1 G protein-coupled receptor associated sorting protein 1 (Synonyms: 2210415K24Rik, 3110031O14Rik, GASP1, mKIAA0443) | |
Results | Reference |
1* | J:210663 Zhou J, Goldberg EM, Leu NA, Zhou L, Coulter DA, Wang PJ, Respiratory failure, cleft palate and epilepsy in the mouse model of human Xq22.1 deletion syndrome. Hum Mol Genet. 2014 Jul 15;23(14):3823-9 |
Gprasp2 G protein-coupled receptor associated sorting protein 2 (Synonyms: 5330440H13Rik, GASP2, Prpl5) | |
Results | Reference |
1* | J:210663 Zhou J, Goldberg EM, Leu NA, Zhou L, Coulter DA, Wang PJ, Respiratory failure, cleft palate and epilepsy in the mouse model of human Xq22.1 deletion syndrome. Hum Mol Genet. 2014 Jul 15;23(14):3823-9 |
Gprc5a G protein-coupled receptor, family C, group 5, member A (Synonyms: Gprc5a, Rai3, Raig1) | |
Results | Reference |
1 | J:247780 Fujimoto J, Nunomura-Nakamura S, Liu Y, Lang W, McDowell T, Jakubek Y, Ezzeddine D, Kapere Ochieng J, Petersen J, Davies G, Fukuoka J, Wistuba II, Ehli E, Fowler J, Scheet P, Kadara H, Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a. Int J Cancer. 2017 Oct 15;141(8):1589-1599 |
2* | J:97487 Xu J, Tian J, Shapiro SD, Normal Lung Development in RAIG1-Deficient Mice Despite Unique Lung Epithelium-Specific Expression. Am J Respir Cell Mol Biol. 2005 May;32(5):381-7 |
Gprc5b G protein-coupled receptor, family C, group 5, member B (Synonyms: hypothetical protein, clone 2-63) | |
Results | Reference |
1* | J:97487 Xu J, Tian J, Shapiro SD, Normal Lung Development in RAIG1-Deficient Mice Despite Unique Lung Epithelium-Specific Expression. Am J Respir Cell Mol Biol. 2005 May;32(5):381-7 |
Gprc5c G protein-coupled receptor, family C, group 5, member C (Synonyms: 1110028I06Rik, 3200002M13Rik) | |
Results | Reference |
2* | J:97487 Xu J, Tian J, Shapiro SD, Normal Lung Development in RAIG1-Deficient Mice Despite Unique Lung Epithelium-Specific Expression. Am J Respir Cell Mol Biol. 2005 May;32(5):381-7 |
Gprc5d G protein-coupled receptor, family C, group 5, member D | |
Results | Reference |
1* | J:97487 Xu J, Tian J, Shapiro SD, Normal Lung Development in RAIG1-Deficient Mice Despite Unique Lung Epithelium-Specific Expression. Am J Respir Cell Mol Biol. 2005 May;32(5):381-7 |
Gpsm1 G-protein signalling modulator 1 (AGS3-like, C. elegans) (Synonyms: 1810037C22Rik, Ags3) | |
Results | Reference |
1 | J:239974 Lacomme M, Tarchini B, Boudreau-Pinsonneault C, Monat C, Cayouette M, The LGN protein promotes planar proliferative divisions in the neocortex but apicobasal asymmetric terminal divisions in the retina. Development. 2016 Feb 15;143(4):575-81 |
Gpsm2 G-protein signalling modulator 2 (AGS3-like, C. elegans) (Synonyms: 6230410J09Rik, LGN, Pins) | |
Results | Reference |
2 | J:235730 Byrd KM, Lough KJ, Patel JH, Descovich CP, Curtis TA, Williams SE, LGN plays distinct roles in oral epithelial stratification, filiform papilla morphogenesis and hair follicle development. Development. 2016 Aug 1;143(15):2803-17 |
1 | J:260456 Duteil D, Tourrette Y, Eberlin A, Willmann D, Patel D, Friedrichs N, Muller JM, Schule R, The histone acetyltransferase inhibitor Nir regulates epidermis development. Development. 2018 Mar 21;145(6):dev158543 |
1 | J:216288 Jones C, Qian D, Kim SM, Li S, Ren D, Knapp L, Sprinzak D, Avraham KB, Matsuzaki F, Chi F, Chen P, Ankrd6 is a mammalian functional homolog of Drosophila planar cell polarity gene diego and regulates coordinated cellular orientation in the mouse inner ear. Dev Biol. 2014 Nov 1;395(1):62-72 |
1 | J:239974 Lacomme M, Tarchini B, Boudreau-Pinsonneault C, Monat C, Cayouette M, The LGN protein promotes planar proliferative divisions in the neocortex but apicobasal asymmetric terminal divisions in the retina. Development. 2016 Feb 15;143(4):575-81 |
1 | J:294113 Lough KJ, Byrd KM, Descovich CP, Spitzer DC, Bergman AJ, Beaudoin GM 3rd, Reichardt LF, Williams SE, Telophase correction refines division orientation in stratified epithelia. Elife. 2019 Dec 13;8:e49249 |
2* | J:149860 Raji B, Dansault A, Vieira V, de la Houssaye G, Lacassagne E, Kobetz A, Arbogast L, Dufier JL, Blumer JB, Menasche M, Abitbol M, Analysis of partner of inscuteable (mPins) expression in the developing mouse eye. Mol Vis. 2008;14:2575-96 |
1 | J:271898 Tadenev ALD, Akturk A, Devanney N, Mathur PD, Clark AM, Yang J, Tarchini B, GPSM2-GNAI Specifies the Tallest Stereocilia and Defines Hair Bundle Row Identity. Curr Biol. 2019 Feb 19; |
1 | J:214064 Tarchini B, Jolicoeur C, Cayouette M, A molecular blueprint at the apical surface establishes planar asymmetry in cochlear hair cells. Dev Cell. 2013 Oct 14;27(1):88-102 |
2* | J:169194 Walsh T, Shahin H, Elkan-Miller T, Lee MK, Thornton AM, Roeb W, Abu Rayyan A, Loulus S, Avraham KB, King MC, Kanaan M, Whole exome sequencing and homozygosity mapping identify mutation in the cell polarity protein GPSM2 as the cause of nonsyndromic hearing loss DFNB82. Am J Hum Genet. 2010 Jul 9;87(1):90-4 |
1* | J:219386 Williams SE, Ratliff LA, Postiglione MP, Knoblich JA, Fuchs E, Par3-mInsc and Galphai3 cooperate to promote oriented epidermal cell divisions through LGN. Nat Cell Biol. 2014 Aug;16(8):758-69 |
Gpx1 glutathione peroxidase 1 (Synonyms: cellular GPx, CGPx, Gpx, GPx-1, GSHPx-1) | |
Results | Reference |
1 | J:100374 Baek IJ, Yon JM, Lee BJ, Yun YW, Yu WJ, Hong JT, Ahn B, Kim YB, Kim DJ, Kang JK, Nam SY, Expression pattern of cytosolic glutathione peroxidase (cGPx) mRNA during mouse embryogenesis. Anat Embryol (Berl). 2005 Apr;209(4):315-21 |
1* | J:186299 Baek IJ, Yon JM, Lee SR, Kim MR, Hong JT, Lee BJ, Yun YW, Nam SY, Differential expression of gastrointestinal glutathione peroxidase (GI-GPx) gene during mouse organogenesis. Anat Histol Embryol. 2011 Jun;40(3):210-8 |
1* | J:17746 de Haan JB, Tymms MJ, Cristiano F, Kola I, Expression of copper/zinc superoxide dismutase and glutathione peroxidase in organs of developing mouse embryos, fetuses, and neonates. Pediatr Res. 1994 Feb;35(2):188-96 |
1 | J:342871 Xiang J, Pompetti AJ, Faranda AP, Wang Y, Novo SG, Li DW, Duncan MK, ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment. Cells. 2023 Nov 16;12(22) |
Gpx2 glutathione peroxidase 2 (Synonyms: GI-GPx, GPx-GI, intestinal GPx) | |
Results | Reference |
2* | J:186299 Baek IJ, Yon JM, Lee SR, Kim MR, Hong JT, Lee BJ, Yun YW, Nam SY, Differential expression of gastrointestinal glutathione peroxidase (GI-GPx) gene during mouse organogenesis. Anat Histol Embryol. 2011 Jun;40(3):210-8 |
Gpx3 glutathione peroxidase 3 (Synonyms: EGPx, extracellular GPx, GPx, plasma GPx) | |
Results | Reference |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
4* | J:177879 Jung KY, Baek IJ, Yon JM, Lee SR, Kim MR, Lee BJ, Yun YW, Nam SY, Developmental expression of plasma glutathione peroxidase during mouse organogenesis. J Mol Histol. 2011 Dec;42(6):545-56 |
1* | J:46116 Kingsley PD, Whitin JC, Cohen HJ, Palis J, Developmental expression of extracellular glutathione peroxidase suggests antioxidant roles in deciduum, visceral yolk sac, and skin. Mol Reprod Dev. 1998 Apr;49(4):343-55 |
Gpx4 glutathione peroxidase 4 (Synonyms: 1700027O09Rik, mtPHGPx, PHGPx, phospholipid hydroperoxide glutathione peroxidase, snGPx, sperm nuclei glutathione peroxidase) | |
Results | Reference |
1* | J:114857 Borchert A, Wang CC, Ufer C, Schiebel H, Savaskan NE, Kuhn H, The role of phospholipid hydroperoxide glutathione peroxidase isoforms in murine embryogenesis. J Biol Chem. 2006 Jul 14;281(28):19655-64 |
1* | J:137422 Ufer C, Wang CC, Fahling M, Schiebel H, Thiele BJ, Billett EE, Kuhn H, Borchert A, Translational regulation of glutathione peroxidase 4 expression through guanine-rich sequence-binding factor 1 is essential for embryonic brain development. Genes Dev. 2008 Jul 1;22(13):1838-50 |
Gpx5 glutathione peroxidase 5 (Synonyms: Arep) | |
Results | Reference |
1* | J:138268 Zhang T, Chabory E, Britan A, Grignard E, Pitiot O, Saez F, Cadet R, Henry-Berger J, Vernet P, Drevet JR, GPX5, the selenium-independent glutathione peroxidase-encoding single copy gene is differentially expressed in mouse epididymis. Reprod Fertil Dev. 2008;20(5):615-25 |
Grb2 growth factor receptor bound protein 2 | |
Results | Reference |
1* | J:14183 Suen KL, Bustelo XR, Pawson T, Barbacid M, Molecular cloning of the mouse grb2 gene: differential interaction of the Grb2 adaptor protein with epidermal growth factor and nerve growth factor receptors. Mol Cell Biol. 1993 Sep;13(9):5500-12 |
Grb10 growth factor receptor bound protein 10 (Synonyms: 5730571D09Rik, maternally expressed gene 1, Meg1, mKIAA0207) | |
Results | Reference |
1 | J:329940 Juan AM, Foong YH, Thorvaldsen JL, Lan Y, Leu NA, Rurik JG, Li L, Krapp C, Rosier CL, Epstein JA, Bartolomei MS, Tissue-specific Grb10/Ddc insulator drives allelic architecture for cardiac development. Mol Cell. 2022 Oct 6;82(19):3613-3631.e7 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Grem1 gremlin 1, DAN family BMP antagonist (Synonyms: Cktsf1b1, Drm, Grem, gremlin) | |
Results | Reference |
1 | J:359451 Amato CM, Xu X, Yao HH, An extragenital cell population contributes to urethra closure during mouse penis development. Sci Adv. 2024 Dec 6;10(49):eadp0673 |
1* | J:154372 Li X, Udager AM, Hu C, Qiao XT, Richards N, Gumucio DL, Dynamic patterning at the pylorus: Formation of an epithelial intestine-stomach boundary in late fetal life. Dev Dyn. 2009 Oct 29;238(12):3205-3217 |
1 | J:286655 Sakamoto S, Tateya T, Omori K, Kageyama R, Id genes are required for morphogenesis and cellular patterning in the developing mammalian cochlea. Dev Biol. 2020 Apr 15;460(2):164-175 |
1 | J:239521 Stzepourginski I, Nigro G, Jacob JM, Dulauroy S, Sansonetti PJ, Eberl G, Peduto L, CD34+ mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E506-E513 |
1* | J:269344 Teng CS, Ting MC, Farmer DT, Brockop M, Maxson RE, Crump JG, Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome. Elife. 2018 Oct 25;7:e37024 |
Grem2 gremlin 2, DAN family BMP antagonist (Synonyms: Prdc) | |
Results | Reference |
1 | J:73145 Lu MM, Yang H, Zhang L, Shu W, Blair DG, Morrisey EE, The bone morphogenic protein antagonist gremlin regulates proximal-distal patterning of the lung. Dev Dyn. 2001 Dec;222(4):667-80 |
Grhl1 grainyhead like transcription factor 1 (Synonyms: LBP-32, p61 MGR, p70 MGR, Tcfcp2l2) | |
Results | Reference |
1* | J:112342 Auden A, Caddy J, Wilanowski T, Ting SB, Cunningham JM, Jane SM, Spatial and temporal expression of the Grainyhead-like transcription factor family during murine development. Gene Expr Patterns. 2006 Dec;6(8):964-70 |
1* | J:266596 Kersbergen A, Best SA, Dworkin S, Ah-Cann C, de Vries ME, Asselin-Labat ML, Ritchie ME, Jane SM, Sutherland KD, Lung morphogenesis is orchestrated through Grainyhead-like 2 (Grhl2) transcriptional programs. Dev Biol. 2018 Nov 1;443(1):1-9 |
Grhl2 grainyhead like transcription factor 2 (Synonyms: 0610015A08Rik, BOM, clft3, grainyheadlike, Tcfcp2l3) | |
Results | Reference |
1* | J:112342 Auden A, Caddy J, Wilanowski T, Ting SB, Cunningham JM, Jane SM, Spatial and temporal expression of the Grainyhead-like transcription factor family during murine development. Gene Expr Patterns. 2006 Dec;6(8):964-70 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1* | J:236149 Edwards W, Nantie LB, Raetzman LT, Identification of a novel progenitor cell marker, grainyhead-like 2 in the developing pituitary. Dev Dyn. 2016 Nov;245(11):1097-1106 |
2* | J:266596 Kersbergen A, Best SA, Dworkin S, Ah-Cann C, de Vries ME, Asselin-Labat ML, Ritchie ME, Jane SM, Sutherland KD, Lung morphogenesis is orchestrated through Grainyhead-like 2 (Grhl2) transcriptional programs. Dev Biol. 2018 Nov 1;443(1):1-9 |
1 | J:220468 Walentin K, Hinze C, Werth M, Haase N, Varma S, Morell R, Aue A, Potschke E, Warburton D, Qiu A, Barasch J, Purfurst B, Dieterich C, Popova E, Bader M, Dechend R, Staff AC, Yurtdas ZY, Kilic E, Schmidt-Ott KM, A Grhl2-dependent gene network controls trophoblast branching morphogenesis. Development. 2015 Mar 15;142(6):1125-36 |
Grhl3 grainyhead like transcription factor 3 (Synonyms: ct, Get1, nmf231, Som) | |
Results | Reference |
1* | J:112342 Auden A, Caddy J, Wilanowski T, Ting SB, Cunningham JM, Jane SM, Spatial and temporal expression of the Grainyhead-like transcription factor family during murine development. Gene Expr Patterns. 2006 Dec;6(8):964-70 |
1 | J:253570 Dworkin S, Auden A, Partridge DD, Daglas M, Medcalf RL, Mantamadiotis T, Georgy SR, Darido C, Jane SM, Ting SB, Grainyhead-like 3 (Grhl3) deficiency in brain leads to altered locomotor activity and decreased anxiety-like behaviors in aged mice. Dev Neurobiol. 2017 Jun;77(6):775-788 |
1* | J:236374 Goldie SJ, Arhatari BD, Anderson P, Auden A, Partridge DD, Jane SM, Dworkin S, Mice lacking the conserved transcription factor Grainyhead-like 3 (Grhl3) display increased apposition of the frontal and parietal bones during embryonic development. BMC Dev Biol. 2016 Oct 18;16(1):37 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1* | J:138857 Hislop NR, Caddy J, Ting SB, Auden A, Vasudevan S, King SL, Lindeman GJ, Visvader JE, Cunningham JM, Jane SM, Grhl3 and Lmo4 play coordinate roles in epidermal migration. Dev Biol. 2008 Sep 1;321(1):263-72 |
1* | J:266596 Kersbergen A, Best SA, Dworkin S, Ah-Cann C, de Vries ME, Asselin-Labat ML, Ritchie ME, Jane SM, Sutherland KD, Lung morphogenesis is orchestrated through Grainyhead-like 2 (Grhl2) transcriptional programs. Dev Biol. 2018 Nov 1;443(1):1-9 |
1 | J:267222 Kimura-Yoshida C, Mochida K, Nakaya MA, Mizutani T, Matsuo I, Cytoplasmic localization of GRHL3 upon epidermal differentiation triggers cell shape change for epithelial morphogenesis. Nat Commun. 2018 Oct 3;9(1):4059 |
1* | J:237529 Salazar VS, Ohte S, Capelo LP, Gamer L, Rosen V, Specification of osteoblast cell fate by canonical Wnt signaling requires Bmp2. Development. 2016 Dec 01;143(23):4352-4367 |
2* | J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903 |
Gria1 glutamate receptor, ionotropic, AMPA1 (alpha 1) (Synonyms: 2900051M01Rik, Glr-1, Glr1, GluA1, Glur-1, Glur1, GluR1, GluR-A, GluRA, HIPA1) | |
Results | Reference |
1* | J:315121 Feng T, Niu M, Ji C, Gao Y, Wen J, Bu G, Xu H, Zhang YW, SNX15 Regulates Cell Surface Recycling of APP and Abeta Generation. Mol Neurobiol. 2016 Aug;53(6):3690-3701 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:250166 Liu K, Lei R, Li Q, Wang XX, Wu Q, An P, Zhang J, Zhu M, Xu Z, Hong Y, Wang F, Shen Y, Li H, Li H, Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity. Sci Rep. 2016 Feb 16;6:21019 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1* | J:40542 Zhang C, Hammassaki-Britto DE, Britto LR, Duvoisin RM, Expression of glutamate receptor subunit genes during development of the mouse retina. Neuroreport. 1996 Dec 20;8(1):335-40 |
Gria2 glutamate receptor, ionotropic, AMPA2 (alpha 2) (Synonyms: GluA2, Glur-2, Glur2, GluR2, GluR-B) | |
Results | Reference |
1 | J:90585 Cheng L, Arata A, Mizuguchi R, Qian Y, Karunaratne A, Gray PA, Arata S, Shirasawa S, Bouchard M, Luo P, Chen CL, Busslinger M, Goulding M, Onimaru H, Ma Q, Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates. Nat Neurosci. 2004 May;7(5):510-7 |
2 | J:104420 Glasgow SM, Henke RM, Macdonald RJ, Wright CV, Johnson JE, Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn. Development. 2005 Dec;132(24):5461-9 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1 | J:130251 Hori K, Cholewa-Waclaw J, Nakada Y, Glasgow SM, Masui T, Henke RM, Wildner H, Martarelli B, Beres TM, Epstein JA, Magnuson MA, Macdonald RJ, Birchmeier C, Johnson JE, A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes Dev. 2008 Jan 15;22(2):166-78 |
1 | J:250166 Liu K, Lei R, Li Q, Wang XX, Wu Q, An P, Zhang J, Zhu M, Xu Z, Hong Y, Wang F, Shen Y, Li H, Li H, Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity. Sci Rep. 2016 Feb 16;6:21019 |
1* | J:40542 Zhang C, Hammassaki-Britto DE, Britto LR, Duvoisin RM, Expression of glutamate receptor subunit genes during development of the mouse retina. Neuroreport. 1996 Dec 20;8(1):335-40 |
Gria3 glutamate receptor, ionotropic, AMPA3 (alpha 3) (Synonyms: 2900064I19Rik, Glur-3, Glur3, GluR3, Gluralpha3) | |
Results | Reference |
2 | J:104420 Glasgow SM, Henke RM, Macdonald RJ, Wright CV, Johnson JE, Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn. Development. 2005 Dec;132(24):5461-9 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1 | J:130251 Hori K, Cholewa-Waclaw J, Nakada Y, Glasgow SM, Masui T, Henke RM, Wildner H, Martarelli B, Beres TM, Epstein JA, Magnuson MA, Macdonald RJ, Birchmeier C, Johnson JE, A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes Dev. 2008 Jan 15;22(2):166-78 |
1* | J:40542 Zhang C, Hammassaki-Britto DE, Britto LR, Duvoisin RM, Expression of glutamate receptor subunit genes during development of the mouse retina. Neuroreport. 1996 Dec 20;8(1):335-40 |
Gria4 glutamate receptor, ionotropic, AMPA4 (alpha 4) (Synonyms: Glur-4, Glur4, Gluralpha4, spkw1) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:40542 Zhang C, Hammassaki-Britto DE, Britto LR, Duvoisin RM, Expression of glutamate receptor subunit genes during development of the mouse retina. Neuroreport. 1996 Dec 20;8(1):335-40 |
Grik1 glutamate receptor, ionotropic, kainate 1 (Synonyms: A830007B11Rik, D16Ium24, D16Ium24e, GluK5, Glur-5, Glur5, Glurbeta1) | |
Results | Reference |
2* | J:193538 Cui S, Du P, Zhou X, Wang H, Developmental expression patterns of kainate receptors in the mouse spinal cord. Neuroreport. 2012 Dec 5;23(17):1012-6 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:40542 Zhang C, Hammassaki-Britto DE, Britto LR, Duvoisin RM, Expression of glutamate receptor subunit genes during development of the mouse retina. Neuroreport. 1996 Dec 20;8(1):335-40 |
Grik2 glutamate receptor, ionotropic, kainate 2 (beta 2) (Synonyms: C130030K03Rik, Glur-6, Glur6, Glurbeta2) | |
Results | Reference |
1 | J:90585 Cheng L, Arata A, Mizuguchi R, Qian Y, Karunaratne A, Gray PA, Arata S, Shirasawa S, Bouchard M, Luo P, Chen CL, Busslinger M, Goulding M, Onimaru H, Ma Q, Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates. Nat Neurosci. 2004 May;7(5):510-7 |
2* | J:193538 Cui S, Du P, Zhou X, Wang H, Developmental expression patterns of kainate receptors in the mouse spinal cord. Neuroreport. 2012 Dec 5;23(17):1012-6 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:40542 Zhang C, Hammassaki-Britto DE, Britto LR, Duvoisin RM, Expression of glutamate receptor subunit genes during development of the mouse retina. Neuroreport. 1996 Dec 20;8(1):335-40 |
Grik3 glutamate receptor, ionotropic, kainate 3 (Synonyms: Glur-7, Glur7) | |
Results | Reference |
2* | J:193538 Cui S, Du P, Zhou X, Wang H, Developmental expression patterns of kainate receptors in the mouse spinal cord. Neuroreport. 2012 Dec 5;23(17):1012-6 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:40542 Zhang C, Hammassaki-Britto DE, Britto LR, Duvoisin RM, Expression of glutamate receptor subunit genes during development of the mouse retina. Neuroreport. 1996 Dec 20;8(1):335-40 |
Grik4 glutamate receptor, ionotropic, kainate 4 (Synonyms: 6330551K01Rik, GluRgamma1, KA-1, KA1) | |
Results | Reference |
2* | J:193538 Cui S, Du P, Zhou X, Wang H, Developmental expression patterns of kainate receptors in the mouse spinal cord. Neuroreport. 2012 Dec 5;23(17):1012-6 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
2 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:45303 Tole S, Christian C, Grove EA, Early specification and autonomous development of cortical fields in the mouse hippocampus. Development. 1997 Dec;124(24):4959-70 |
1* | J:40542 Zhang C, Hammassaki-Britto DE, Britto LR, Duvoisin RM, Expression of glutamate receptor subunit genes during development of the mouse retina. Neuroreport. 1996 Dec 20;8(1):335-40 |
Grik5 glutamate receptor, ionotropic, kainate 5 (gamma 2) (Synonyms: GluRgamma2, KA2) | |
Results | Reference |
2* | J:193538 Cui S, Du P, Zhou X, Wang H, Developmental expression patterns of kainate receptors in the mouse spinal cord. Neuroreport. 2012 Dec 5;23(17):1012-6 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:40542 Zhang C, Hammassaki-Britto DE, Britto LR, Duvoisin RM, Expression of glutamate receptor subunit genes during development of the mouse retina. Neuroreport. 1996 Dec 20;8(1):335-40 |
Grin1 glutamate receptor, ionotropic, NMDA1 (zeta 1) (Synonyms: GluRzeta1, M100174, Nmdar, NMDAR1, NR1, Rgsc174) | |
Results | Reference |
1 | J:336861 Folorunso OO, Brown SE, Baruah J, Harvey TL, Jami SA, Radzishevsky I, Wolosker H, McNally JM, Gray JA, Vasudevan A, Balu DT, D-serine availability modulates prefrontal cortex inhibitory interneuron development and circuit maturation. Sci Rep. 2023 Jun 13;13(1):9595 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
3 | J:94801 Wang TF, Ding CN, Wang GS, Luo SC, Lin YL, Ruan Y, Hevner R, Rubenstein JL, Hsueh YP, Identification of Tbr-1/CASK complex target genes in neurons. J Neurochem. 2004 Dec;91(6):1483-92 |
Grin2a glutamate receptor, ionotropic, NMDA2A (epsilon 1) (Synonyms: GluN2A, GluRepsilon1, NMDAR2A, NR2A) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Grin2b glutamate receptor, ionotropic, NMDA2B (epsilon 2) (Synonyms: GluN2B, GluRepsilon2, Nmdar2b, NMDAR2B, NR2B) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
3 | J:94801 Wang TF, Ding CN, Wang GS, Luo SC, Lin YL, Ruan Y, Hevner R, Rubenstein JL, Hsueh YP, Identification of Tbr-1/CASK complex target genes in neurons. J Neurochem. 2004 Dec;91(6):1483-92 |
Grin2c glutamate receptor, ionotropic, NMDA2C (epsilon 3) (Synonyms: GluRepsilon3, NMDAR2C, NR2C) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Grin2d glutamate receptor, ionotropic, NMDA2D (epsilon 4) (Synonyms: GluN2D, GluRepsilon4, NMDAR2D, NR2D) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Grin3a glutamate receptor ionotropic, NMDA3A (Synonyms: A830097C19Rik, NMDAR-L, NR3A) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Grin3b glutamate receptor, ionotropic, NMDA3B (Synonyms: NR3B) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Grina glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding) (Synonyms: 1110025J15Rik, Tmbim3) | |
Results | Reference |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Grk2 G protein-coupled receptor kinase 2 (Synonyms: Adrbk-1, Adrbk1, Bark-1, beta-adrenergic receptor kinase-1, beta ARK, beta ARK1, betaARK1, beta-AR kinase-1) | |
Results | Reference |
1* | J:65649 Sefton M, Blanco MJ, Penela P, Mayor F, Nieto MA, Expression of the G protein-coupled receptor kinase 2 during early mouse embryogenesis. Mech Dev. 2000 Nov;98(1-2):127-31 |
Grm1 glutamate receptor, metabotropic 1 (Synonyms: 4930455H15Rik, Gprc1a, Grm1, mGluR1, nmf373, rcw) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:96195 Sato Y, Hirata T, Ogawa M, Fujisawa H, Requirement for early-generated neurons recognized by monoclonal antibody lot1 in the formation of lateral olfactory tract. J Neurosci. 1998 Oct 1;18(19):7800-10 |
Grm2 glutamate receptor, metabotropic 2 (Synonyms: 4930441L02Rik, Gprc1b, mGluR2) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Grm3 glutamate receptor, metabotropic 3 (Synonyms: 0710001G23Rik, Gprc1c, mGlu3, mGluR3) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Grm4 glutamate receptor, metabotropic 4 (Synonyms: Gprc1d, mGluR4) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Grm5 glutamate receptor, metabotropic 5 (Synonyms: 6430542K11Rik, Glu5R, Gprc1e, mGluR5) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Grm6 glutamate receptor, metabotropic 6 (Synonyms: mGluR6, nerg1, nob3) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Grm7 glutamate receptor, metabotropic 7 (Synonyms: 6330570A01Rik, E130018M02Rik, Gpr1g, mGlu7a receptor, mGluR7) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Grm8 glutamate receptor, metabotropic 8 (Synonyms: Gprc1h, mGluR8) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Grn granulin (Synonyms: acrogranulin, epithelin, PC cell-derived growth factor, Pgrn, progranulin) | |
Results | Reference |
1* | J:84942 Daniel R, Daniels E, He Z, Bateman A, Progranulin (acrogranin/PC cell-derived growth factor/granulin-epithelin precursor) is expressed in the placenta, epidermis, microvasculature, and brain during murine development. Dev Dyn. 2003 Aug;227(4):593-9 |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Grp gastrin releasing peptide (Synonyms: BLP, MGC:37475) | |
Results | Reference |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
Grpr gastrin releasing peptide receptor (Synonyms: bombesin receptor, GRP-R) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1 | J:201733 Xu Y, Lopes C, Wende H, Guo Z, Cheng L, Birchmeier C, Ma Q, Ontogeny of excitatory spinal neurons processing distinct somatic sensory modalities. J Neurosci. 2013 Sep 11;33(37):14738-48 |
1 | J:207050 Zhao X, Huang H, Chen Y, Liu Y, Zhang Z, Ma Q, Qiu M, Dynamic expression of secreted Frizzled-related protein 3 (sFRP3) in the developing mouse spinal cord and dorsal root ganglia. Neuroscience. 2013 Sep 17;248:594-601 |
Grsf1 G-rich RNA sequence binding factor 1 (Synonyms: D5Wsu31e) | |
Results | Reference |
1* | J:137422 Ufer C, Wang CC, Fahling M, Schiebel H, Thiele BJ, Billett EE, Kuhn H, Borchert A, Translational regulation of glutathione peroxidase 4 expression through guanine-rich sequence-binding factor 1 is essential for embryonic brain development. Genes Dev. 2008 Jul 1;22(13):1838-50 |
Gsc goosecoid homeobox (Synonyms: goosecoid) | |
Results | Reference |
1* | J:206666 Parry DA, Logan CV, Stegmann AP, Abdelhamed ZA, Calder A, Khan S, Bonthron DT, Clowes V, Sheridan E, Ghali N, Chudley AE, Dobbie A, Stumpel CT, Johnson CA, SAMS, a syndrome of short stature, auditory-canal atresia, mandibular hypoplasia, and skeletal abnormalities is a unique neurocristopathy caused by mutations in Goosecoid. Am J Hum Genet. 2013 Dec 5;93(6):1135-42 |
1 | J:347618 Qin T, So KKH, Hui CC, Sham MH, Ptch1 is essential for cochlear marginal cell differentiation and stria vascularis formation. Cell Rep. 2024 Apr 23;43(4):114083 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Gsk3a glycogen synthase kinase 3 alpha (Synonyms: 2700086H06Rik) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
1 | J:99501 Wang J, Ito T, Udaka N, Okudela K, Yazawa T, Kitamura H, PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung. Tissue Cell. 2005 Feb;37(1):25-35 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
Gsk3b glycogen synthase kinase 3 beta (Synonyms: 7330414F15Rik, 8430431H08Rik, GSK-3, GSK3, GSK-3beta) | |
Results | Reference |
1* | J:279271 Ellis K, Driver EC, Okano T, Lemons A, Kelley MW, GSK3 regulates hair cell fate in the developing mammalian cochlea. Dev Biol. 2019 Sep 15;453(2):191-205 |
1 | J:100687 Mill P, Mo R, Hu MC, Dagnino L, Rosenblum ND, Hui CC, Shh controls epithelial proliferation via independent pathways that converge on N-Myc. Dev Cell. 2005 Aug;9(2):293-303 |
1* | J:311540 Oliver BL, Young CA, Munnamalai V, Spatial and temporal expression of PORCN is highly dynamic in the developing mouse cochlea. Gene Expr Patterns. 2021 Sep 20;42:119214 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
1 | J:139368 Wang G, Krishnamurthy K, Chiang YW, Dasgupta S, Bieberich E, Regulation of neural progenitor cell motility by ceramide and potential implications for mouse brain development. J Neurochem. 2008 Jul;106(2):718-33 |
1 | J:99501 Wang J, Ito T, Udaka N, Okudela K, Yazawa T, Kitamura H, PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung. Tissue Cell. 2005 Feb;37(1):25-35 |
1 | J:305176 Wei Y, Han X, Zhao C, PDK1 regulates the survival of the developing cortical interneurons. Mol Brain. 2020 May 4;13(1):65 |
2 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1 | J:285763 Xu M, Han X, Liu R, Li Y, Qi C, Yang Z, Zhao C, Gao J, PDK1 Deficit Impairs the Development of the Dentate Gyrus in Mice. Cereb Cortex. 2019 Mar 1;29(3):1185-1198 |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
Gsn gelsolin | |
Results | Reference |
1 | J:56669 Arai M, Kwiatkowski DJ, Differential developmentally regulated expression of gelsolin family members in the mouse. Dev Dyn. 1999 Aug;215(4):297-307 |
Gstm6 glutathione S-transferase, mu 6 | |
Results | Reference |
2* | J:150223 Beverdam A, Svingen T, Bagheri-Fam S, Bernard P, McClive P, Robson M, Khojasteh MB, Salehi M, Sinclair AH, Harley VR, Koopman P, Sox9-dependent expression of Gstm6 in Sertoli cells during testis development in mice. Reproduction. 2009 Mar;137(3):481-6 |
1 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
Gstp1 glutathione S-transferase, pi 1 (Synonyms: Gst p-1, GstpiB) | |
Results | Reference |
1 | J:205632 Saito A, Kanemoto S, Kawasaki N, Asada R, Iwamoto H, Oki M, Miyagi H, Izumi S, Sanosaka T, Nakashima K, Imaizumi K, Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun. 2012;3:967 |
Gstp2 glutathione S-transferase, pi 2 (Synonyms: Gst-3, Gst3, Gst p-2, GSTpiA) | |
Results | Reference |
1 | J:205632 Saito A, Kanemoto S, Kawasaki N, Asada R, Iwamoto H, Oki M, Miyagi H, Izumi S, Sanosaka T, Nakashima K, Imaizumi K, Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun. 2012;3:967 |
Gsx1 GS homeobox 1 (Synonyms: Gsh-1, Gsh1) | |
Results | Reference |
1 | J:265822 Chapman H, Riesenberg A, Ehrman LA, Kohli V, Nardini D, Nakafuku M, Campbell K, Waclaw RR, Gsx transcription factors control neuronal versus glial specification in ventricular zone progenitors of the mouse lateral ganglionic eminence. Dev Biol. 2018 Oct 1;442(1):115-126 |
1* | J:72724 Toresson H, Campbell K, A role for Gsh1 in the developing striatum and olfactory bulb of Gsh2 mutant mice. Development. 2001 Dec;128(23):4769-80 |
2 | J:147161 Wang B, Waclaw RR, Allen ZJ 2nd, Guillemot F, Campbell K, Ascl1 is a required downstream effector of Gsx gene function in the embryonic mouse telencephalon. Neural Dev. 2009;4:5 |
Gsx2 GS homeobox 2 (Synonyms: Gsh-2, Gsh2) | |
Results | Reference |
1 | J:309450 Doeppner TR, Herz J, Bahr M, Tonchev AB, Stoykova A, Zbtb20 Regulates Developmental Neurogenesis in the Olfactory Bulb and Gliogenesis After Adult Brain Injury. Mol Neurobiol. 2019 Jan;56(1):567-582 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1* | J:252114 Kohli V, Nardini D, Ehrman LA, Waclaw RR, Characterization of Glcci1 expression in a subpopulation of lateral ganglionic eminence progenitors in the mouse telencephalon. Dev Dyn. 2018 Jan;247(1):222-228 |
1 | J:348287 Liang XG, Hoang K, Meyerink BL, Kc P, Paraiso K, Wang L, Jones IR, Zhang Y, Katzman S, Finn TS, Tsyporin J, Qu F, Chen Z, Visel A, Kriegstein A, Shen Y, Pilaz LJ, Chen B, A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex. Proc Natl Acad Sci U S A. 2024 May 14;121(20):e2321711121 |
2 | J:328992 Manuel M, Tan KB, Kozic Z, Molinek M, Marcos TS, Razak MFA, Dobolyi D, Dobie R, Henderson BEP, Henderson NC, Chan WK, Daw MI, Mason JO, Price DJ, Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals. PLoS Biol. 2022 Sep;20(9):e3001563 |
1 | J:240536 Martin-Ibanez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Garcia-Diaz Barriga G, Edel MJ, Vicario-Abejon C, Alberch J, Girault JA, Chan S, Kastner P, Canals JM, Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017 Apr 15;144(8):1566-1577 |
1 | J:168327 Pei Z, Wang B, Chen G, Nagao M, Nakafuku M, Campbell K, Homeobox genes Gsx1 and Gsx2 differentially regulate telencephalic progenitor maturation. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1675-80 |
1* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1* | J:64588 Toresson H, Potter SS, Campbell K, Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for pax6 and gsh2. Development. 2000 Oct;127(20):4361-71 |
2 | J:147161 Wang B, Waclaw RR, Allen ZJ 2nd, Guillemot F, Campbell K, Ascl1 is a required downstream effector of Gsx gene function in the embryonic mouse telencephalon. Neural Dev. 2009;4:5 |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
2 | J:264125 Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z, SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. Development. 2018 Jul 23;145(14):dev165456 |
1 | J:288251 Zhang Y, Liu G, Guo T, Liang XG, Du H, Yang L, Bhaduri A, Li X, Xu Z, Zhang Z, Li Z, He M, Tsyporin J, Kriegstein AR, Rubenstein JL, Yang Z, Chen B, Cortical Neural Stem Cell Lineage Progression Is Regulated by Extrinsic Signaling Molecule Sonic Hedgehog. Cell Rep. 2020 Mar 31;30(13):4490-4504.e4 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
Gt(ROSA)26Sor gene trap ROSA 26, Philippe Soriano (Synonyms: beta geo, Gtrgeo26, Gtrosa26, R26, ROSA26, Thumpd3as1) | |
Results | Reference |
1 | J:206321 Veniaminova NA, Vagnozzi AN, Kopinke D, Do TT, Murtaugh LC, Maillard I, Dlugosz AA, Reiter JF, Wong SY, Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. Development. 2013 Dec;140(24):4870-80 |
Gtf2b general transcription factor IIB (Synonyms: MGC:6859) | |
Results | Reference |
1* | J:168653 Sylvestersen KB, Herrera PL, Serup P, Rescan C, Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):105-11 |
Gtf2ird1 general transcription factor II I repeat domain-containing 1 (Synonyms: BEN, binding factor for early enhancer, Cream1, ESTM9, GTF3, MusTRD1, WBSCR11) | |
Results | Reference |
1* | J:85875 Bayarsaihan D, Bitchevaia N, Enkhmandakh B, Tussie-Luna MI, Leckman JF, Roy A, Ruddle F, Expression of BEN, a member of TFII-I family of transcription factors, during mouse pre- and postimplantation development. Gene Expr Patterns. 2003 Oct;3(5):579-89 |
Gtsf1 gametocyte specific factor 1 (Synonyms: 1700006H03Rik, Cue110) | |
Results | Reference |
1* | J:147416 Krotz SP, Ballow DJ, Choi Y, Rajkovic A, Expression and localization of the novel and highly conserved gametocyte-specific factor 1 during oogenesis and spermatogenesis. Fertil Steril. 2009 May;91(5 Suppl):2020-4 |
1* | J:127127 Yoshimura T, Miyazaki T, Toyoda S, Miyazaki S, Tashiro F, Yamato E, Miyazaki J, Gene expression pattern of Cue110: A member of the uncharacterized UPF0224 gene family preferentially expressed in germ cells. Gene Expr Patterns. 2007 Dec;8(1):27-35 |
Gtsf1l gametocyte specific factor 1-like (Synonyms: 2410116G06Rik) | |
Results | Reference |
1* | J:251285 Takemoto N, Yoshimura T, Miyazaki S, Tashiro F, Miyazaki J, Gtsf1l and Gtsf2 Are Specifically Expressed in Gonocytes and Spermatids but Are Not Essential for Spermatogenesis. PLoS One. 2016;11(3):e0150390 |
Gtsf2 gametocyte specific factor 2 (Synonyms: BC048502, MGC:58362) | |
Results | Reference |
1* | J:251285 Takemoto N, Yoshimura T, Miyazaki S, Tashiro F, Miyazaki J, Gtsf1l and Gtsf2 Are Specifically Expressed in Gonocytes and Spermatids but Are Not Essential for Spermatogenesis. PLoS One. 2016;11(3):e0150390 |
Gulo gulonolactone (L-) oxidase (Synonyms: L-gulono-gamma-lactone oxidase, MGC:29968, MGC:37793, MGC:37880, sfx) | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Gusb glucuronidase, beta (Synonyms: adipose storage deficiency, asd, g, Gur, Gus, Gus-r, Gus-s, Gus-t, Gus-u, Gut) | |
Results | Reference |
1 | J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90 |
Gyg1 glycogenin 1 (Synonyms: Gyg) | |
Results | Reference |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
Gys1 glycogen synthase 1, muscle (Synonyms: Gys3, MGS) | |
Results | Reference |
1* | J:132397 Cifuentes D, Martinez-Pons C, Garcia-Rocha M, Galina A, de Pouplana LR, Guinovart JJ, Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver. J Biol Chem. 2008 Feb 29;283(9):5642-9 |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
Gys2 glycogen synthase 2 (Synonyms: glycogen synthase, liver, LGS, MGC:29379) | |
Results | Reference |
1* | J:132397 Cifuentes D, Martinez-Pons C, Garcia-Rocha M, Galina A, de Pouplana LR, Guinovart JJ, Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver. J Biol Chem. 2008 Feb 29;283(9):5642-9 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
H2-Ab1 histocompatibility 2, class II antigen A, beta 1 (Synonyms: A beta, Abeta, H2-Ab, H-2Ab, Ia-2, Ia2, I-A, IAb, I-Abeta, Rmcs1) | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
H2-D1 histocompatibility 2, D region locus 1 (Synonyms: H-2D) | |
Results | Reference |
1 | J:192449 Liu J, Shen Y, Li M, Shi Q, Zhang A, Miao F, Liu J, Wu X, He Y, Zhang J, The expression pattern of classical MHC class I molecules in the development of mouse central nervous system. Neurochem Res. 2013 Feb;38(2):290-9 |
H2-M3 histocompatibility 2, M region locus 3 (Synonyms: H-2M3, Hmt, R4B2) | |
Results | Reference |
1* | J:225528 Liu J, Shen Y, Li M, Lv D, Zhang A, Peng Y, Miao F, Zhang J, Spatial-Temporal Expression of Non-classical MHC Class I Molecules in the C57 Mouse Brain. Neurochem Res. 2015 Jul;40(7):1487-96 |
H2-Q1 histocompatibility 2, Q region locus 1 (Synonyms: H-2Q1, Q1, Q1b, Q1d, Q1k) | |
Results | Reference |
1 | J:32567 Wang Q, Flaherty L, Developmental expression of the mouse MHC Q genes. Eur J Immunogenet. 1996 Apr;23(2):121-7 |
H2-Q4 histocompatibility 2, Q region locus 4 (Synonyms: H2-Gs10, H-2Q4, Qa-4, Qa4, Qat-4, Qb-1, Qb1) | |
Results | Reference |
1 | J:32567 Wang Q, Flaherty L, Developmental expression of the mouse MHC Q genes. Eur J Immunogenet. 1996 Apr;23(2):121-7 |
H2-Q6 histocompatibility 2, Q region locus 6 (Synonyms: 0610037M15Rik, H-2Q6, Qa-6, Qa6) | |
Results | Reference |
1 | J:32567 Wang Q, Flaherty L, Developmental expression of the mouse MHC Q genes. Eur J Immunogenet. 1996 Apr;23(2):121-7 |
H2-Q8 histocompatibility 2, Q region locus 8 (Synonyms: H-2Q8, Qa-8, Qa8) | |
Results | Reference |
1 | J:32567 Wang Q, Flaherty L, Developmental expression of the mouse MHC Q genes. Eur J Immunogenet. 1996 Apr;23(2):121-7 |
H2ac25 H2A clustered histone 25 (Synonyms: H2aw, Hist3h2a) | |
Results | Reference |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
H2ax H2A.X variant histone (Synonyms: gammaH2ax, H2afx, H2A.X, Hist5-2ax) | |
Results | Reference |
1 | J:227638 Alvarez S, Diaz M, Flach J, Rodriguez-Acebes S, Lopez-Contreras AJ, Martinez D, Canamero M, Fernandez-Capetillo O, Isern J, Passegue E, Mendez J, Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality. Nat Commun. 2015;6:8548 |
1 | J:324533 Calderon L, Weiss FD, Beagan JA, Oliveira MS, Georgieva R, Wang YF, Carroll TS, Dharmalingam G, Gong W, Tossell K, de Paola V, Whilding C, Ungless MA, Fisher AG, Phillips-Cremins JE, Merkenschlager M, Cohesin-dependence of neuronal gene expression relates to chromatin loop length. Elife. 2022 Apr 26;11:e76539 |
1 | J:300487 Chai G, Webb A, Li C, Antaki D, Lee S, Breuss MW, Lang N, Stanley V, Anzenberg P, Yang X, Marshall T, Gaffney P, Wierenga KJ, Chung BH, Tsang MH, Pais LS, Lovgren AK, VanNoy GE, Rehm HL, Mirzaa G, Leon E, Diaz J, Neumann A, Kalverda AP, Manfield IW, Parry DA, Logan CV, Johnson CA, Bonthron DT, Valleley EMA, Issa MY, Abdel-Ghafar SF, Abdel-Hamid MS, Jennings P, Zaki MS, Sheridan E, Gleeson JG, Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 Jan 20;109(2):241-256.e9 |
1 | J:179634 Chassot AA, Gregoire EP, Lavery R, Taketo MM, de Rooij DG, Adams IR, Chaboissier MC, RSPO1/beta-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary. PLoS One. 2011;6(10):e25641 |
1 | J:196310 Ene AC, Park S, Edelmann W, Taketo T, Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression. Dev Biol. 2013 May 1;377(1):213-23 |
1 | J:211663 Fukuda T, Fukuda N, Agostinho A, Hernandez-Hernandez A, Kouznetsova A, Hoog C, STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. EMBO J. 2014 Jun 2;33(11):1243-55 |
1 | J:208416 Holt JE, Pye V, Boon E, Stewart JL, Garcia-Higuera I, Moreno S, Rodriguez R, Jones KT, McLaughlin EA, The APC/C activator FZR1 is essential for meiotic prophase I in mice. Development. 2014 Mar;141(6):1354-65 |
1 | J:326085 Huang TC, Wang YF, Vazquez-Ferrer E, Theofel I, Requena CE, Hanna CW, Kelsey G, Hajkova P, Sex-specific chromatin remodelling safeguards transcription in germ cells. Nature. 2021 Dec;600(7890):737-742 |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
1* | J:231259 Krill KT, Gurdziel K, Heaton JH, Simon DP, Hammer GD, Dicer deficiency reveals microRNAs predicted to control gene expression in the developing adrenal cortex. Mol Endocrinol. 2013 May;27(5):754-68 |
1 | J:181920 Lee Y, Shull ER, Frappart PO, Katyal S, Enriquez-Rios V, Zhao J, Russell HR, Brown EJ, McKinnon PJ, ATR maintains select progenitors during nervous system development. EMBO J. 2012 Mar 7;31(5):1177-89 |
1* | J:347585 Leon NY, Le TNU, Garvie A, Wong LH, Bagheri-Fam S, Harley VR, Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. iScience. 2024 May 17;27(5):109629 |
1* | J:226736 Li X, Li L, Li J, Sipple J, Schick J, Mehta PA, Davies SM, Dasgupta B, Waclaw RR, Pang Q, Concomitant inactivation of foxo3a and fancc or fancd2 reveals a two-tier protection from oxidative stress-induced hydrocephalus. Antioxid Redox Signal. 2014 Oct 20;21(12):1675-92 |
1 | J:352165 Lin Y, Tang W, Huang P, Wang Z, Duan L, Jia C, Sun R, Liu L, Shen J, Denticleless E3 ubiquitin protein ligase (DTL) maintains the proliferation and differentiation of epidermis and hair follicles during skin development. Dev Dyn. 2024 Jul;253(7):635-647 |
1 | J:330439 Liu H, He L, Cheng Q, Luo W, Zhao T, Yang D, Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states. Int J Mol Med. 2022 Nov;50(5) |
1* | J:173838 Manuylov NL, Zhou B, Ma Q, Fox SC, Pu WT, Tevosian SG, Conditional ablation of Gata4 and Fog2 genes in mice reveals their distinct roles in mammalian sexual differentiation. Dev Biol. 2011 May 15;353(2):229-41 |
1 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
1 | J:210514 Martinez P, Ferrara-Romeo I, Flores JM, Blasco MA, Essential role for the TRF2 telomere protein in adult skin homeostasis. Aging Cell. 2014 Aug;13(4):656-68 |
1 | J:185038 Martinez P, Flores JM, Blasco MA, 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response. J Cell Biol. 2012 Apr 16;197(2):283-300 |
1 | J:198698 Meng L, Lin T, Peng G, Hsu JK, Lee S, Lin SY, Tsai RY, Nucleostemin deletion reveals an essential mechanism that maintains the genomic stability of stem and progenitor cells. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11415-20 |
1 | J:158526 Naillat F, Prunskaite-Hyyrylainen R, Pietila I, Sormunen R, Jokela T, Shan J, Vainio SJ, Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development. Hum Mol Genet. 2010 Apr 15;19(8):1539-50 |
1* | J:326026 Prokopuk L, Jarred EG, Blucher RO, McLaughlin EA, Stringer JM, Western PS, An essential role for Polycomb Repressive Complex 2 in the mouse ovary. Reproduction. 2022 Feb 17;163(3):167-182 |
1 | J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088 |
1* | J:209131 Saba R, Wu Q, Saga Y, CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways. Dev Biol. 2014 May 15;389(2):173-81 |
1 | J:123269 Tachibana M, Nozaki M, Takeda N, Shinkai Y, Functional dynamics of H3K9 methylation during meiotic prophase progression. EMBO J. 2007 Jul 25;26(14):3346-59 |
1 | J:163097 Thoren LA, Norgaard GA, Weischenfeldt J, Waage J, Jakobsen JS, Damgaard I, Bergstrom FC, Blom AM, Borup R, Bisgaard HC, Porse BT, UPF2 is a critical regulator of liver development, function and regeneration. PLoS One. 2010;5(7):e11650 |
1 | J:333324 Tominaga K, Sakashita E, Kasashima K, Kuroiwa K, Nagao Y, Iwamori N, Endo H, Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells. Int J Mol Sci. 2023 Jan 20;24(3) |
1 | J:343099 Tonosaki M, Fujimori A, Yaoi T, Itoh K, Loss of Aspm causes increased apoptosis of developing neural cells during mouse cerebral corticogenesis. PLoS One. 2023;18(11):e0294893 |
1 | J:299668 Uyeda A, Onishi K, Hirayama T, Hattori S, Miyakawa T, Yagi T, Yamamoto N, Sugo N, Suppression of DNA Double-Strand Break Formation by DNA Polymerase beta in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons. J Neurosci. 2020 Nov 18;40(47):9012-9027 |
1 | J:281207 Vazquez BN, Blengini CS, Hernandez Y, Serrano L, Schindler K, SIRT7 promotes chromosome synapsis during prophase I of female meiosis. Chromosoma. 2019 Sep;128(3):369-383 |
1 | J:165054 Wang WL, Li Q, Xu J, Cvekl A, Lens fiber cell differentiation and denucleation are disrupted through expression of the N-terminal nuclear receptor box of NCOA6 and result in p53-dependent and p53-independent apoptosis. Mol Biol Cell. 2010 Jul 15;21(14):2453-68 |
1* | J:261042 Welcker D, Jain M, Khurshid S, Jokic M, Hohne M, Schmitt A, Frommolt P, Niessen CM, Spiro J, Persigehl T, Wittersheim M, Buttner R, Fanciulli M, Schermer B, Reinhardt HC, Benzing T, Hopker K, AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer. Oncogene. 2018 Mar;37(11):1503-1518 |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
1 | J:194101 Yamaguchi S, Hong K, Liu R, Shen L, Inoue A, Diep D, Zhang K, Zhang Y, Tet1 controls meiosis by regulating meiotic gene expression. Nature. 2012 Dec 20;492(7429):443-7 |
1 | J:299730 Zhang L, Jing H, Li H, Chen W, Luo B, Zhang H, Dong Z, Li L, Su H, Xiong WC, Mei L, Neddylation is critical to cortical development by regulating Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26448-26459 |
1 | J:362758 Zhang L, Li Y, Hu Y, Chen M, Cen C, Chen M, Lin L, Zhou J, Wang M, Cui X, Tang F, Gao F, Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression. FASEB J. 2022 Feb;36(2):e22131 |
1 | J:328995 Zhang SF, Dai SK, Du HZ, Wang H, Li XG, Tang Y, Liu CM, The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis. Stem Cell Reports. 2022 Sep 13;17(9):2064-2080 |
H2az1 H2A.Z variant histone 1 (Synonyms: H2afz, H2A.Z, H2A.Z1) | |
Results | Reference |
1* | J:227084 Kafer GR, Carlton PM, Lehnert SA, The histone variant H2A.Z is dynamically expressed in the developing mouse placenta and in differentiating trophoblast stem cells. Placenta. 2015 Nov;36(11):1325-8 |
1* | J:305946 Xu M, Yao J, Shi Y, Yi H, Zhao W, Lin X, Yang Z, The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026 |
H2az2 H2A.Z histone variant 2 (Synonyms: C530002L11Rik, H2afv, H2A.Z2) | |
Results | Reference |
2* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
H3f3a H3.3 histone A (Synonyms: H3-3a, H3.3A) | |
Results | Reference |
2* | J:58812 Couldrey C, Carlton MB, Nolan PM, Colledge WH, Evans MJ, A retroviral gene trap insertion into the histone 3.3A gene causes partial neonatal lethality, stunted growth, neuromuscular deficits and male sub-fertility in transgenic mice. Hum Mol Genet. 1999 Dec;8(13):2489-95 |
H3f3b H3.3 histone B (Synonyms: 9430068D06Rik, H3-3b, H3.3B) | |
Results | Reference |
1* | J:120114 Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY, A biphasic pattern of gene expression during mouse retina development. BMC Dev Biol. 2006;6:48 |
H4c3 H4 clustered histone 3 (Synonyms: Hist1h4c) | |
Results | Reference |
1 | J:170582 Mundy C, Yasuda T, Kinumatsu T, Yamaguchi Y, Iwamoto M, Enomoto-Iwamoto M, Koyama E, Pacifici M, Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine. Dev Biol. 2011 Mar 1;351(1):70-81 |
H4c16 H4 histone 16 (Synonyms: B130044J01Rik, H4-16, H4f16, Hist4h4) | |
Results | Reference |
1 | J:316972 Mehta A, Dobersch S, Dammann RH, Bellusci S, Ilinskaya ON, Braun T, Barreto G, Validation of Tuba1a as appropriate internal control for normalization of gene expression analysis during mouse lung development. Int J Mol Sci. 2015 Feb 25;16(3):4492-511 |
H19 H19, imprinted maternally expressed transcript | |
Results | Reference |
1 | J:153616 Gabory A, Ripoche MA, Le Digarcher A, Watrin F, Ziyyat A, Forne T, Jammes H, Ainscough JF, Surani MA, Journot L, Dandolo L, H19 acts as a trans regulator of the imprinted gene network controlling growth in mice. Development. 2009 Oct;136(20):3413-21 |
2* | J:283316 Garcia-Padilla C, Dominguez JN, Aranega AE, Franco D, Differential chamber-specific expression and regulation of long non-coding RNAs during cardiac development. Biochim Biophys Acta Gene Regul Mech. 2019 Oct;1862(10):194435 |
1 | J:218430 Kamimura S, Hatanaka Y, Hirasawa R, Matsumoto K, Oikawa M, Lee J, Matoba S, Mizutani E, Ogonuki N, Inoue K, Kohda T, Ishino F, Ogura A, Establishment of paternal genomic imprinting in mouse prospermatogonia analyzed by nuclear transfer. Biol Reprod. 2014 Nov;91(5):120 |
1* | J:267655 Marjonen H, Toivonen M, Lahti L, Kaminen-Ahola N, Early prenatal alcohol exposure alters imprinted gene expression in placenta and embryo in a mouse model. PLoS One. 2018;13(5):e0197461 |
2 | J:335099 Naing BT, Takizawa T, Sakurai T, Kyi-Tha-Thu C, Takizawa T, Possible transfer of lncRNA H19-derived miRNA miR-675-3p to adjacent H19-non-expressing trophoblast cells in near-term mouse placenta. Histochem Cell Biol. 2023 Apr;159(4):363-375 |
1* | J:272586 Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, Yamamoto T, Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019 Feb 15;146(4):dev168146 |
1 | J:30428 Szabo PE, Mann JR, Allele-specific expression and total expression levels of imprinted genes during early mouse development: implications for imprinting mechanisms. Genes Dev. 1995 Dec 15;9(24):3097-108 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1* | J:41607 Tremblay KD, Duran KL, Bartolomei MS, A 5' 2-kilobase-pair region of the imprinted mouse H19 gene exhibits exclusive paternal methylation throughout development. Mol Cell Biol. 1997 Aug;17(8):4322-9 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1* | J:230499 Wang S, Wu X, Liu Y, Yuan J, Yang F, Huang J, Meng Q, Zhou C, Liu F, Ma J, Sun S, Zheng J, Wang F, Long noncoding RNA H19 inhibits the proliferation of fetal liver cells and the Wnt signaling pathway. FEBS Lett. 2016 Feb;590(4):559-70 |
Hamp hepcidin antimicrobial peptide (Synonyms: Hepc, HEPC1) | |
Results | Reference |
1 | J:98335 Mok H, Mendoza M, Prchal JT, Balogh P, Schumacher A, Dysregulation of ferroportin 1 interferes with spleen organogenesis in polycythaemia mice. Development. 2004 Oct;131(19):4871-81 |
Hamp2 hepcidin antimicrobial peptide 2 (Synonyms: 1810073K19Rik, HEPC2) | |
Results | Reference |
1 | J:98335 Mok H, Mendoza M, Prchal JT, Balogh P, Schumacher A, Dysregulation of ferroportin 1 interferes with spleen organogenesis in polycythaemia mice. Development. 2004 Oct;131(19):4871-81 |
Hand1 heart and neural crest derivatives expressed 1 (Synonyms: bHLHa27, eHAND, Ehand1, Hxt, Th1, Thing1) | |
Results | Reference |
1 | J:332132 Cattaneo P, Hayes MGB, Baumgarten N, Hecker D, Peruzzo S, Aslan GS, Kunderfranco P, Larcher V, Zhang L, Contu R, Fonseca G, Spinozzi S, Chen J, Condorelli G, Dimmeler S, Schulz MH, Heinz S, Guimaraes-Camboa N, Evans SM, DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal. Nat Commun. 2022 Dec 2;13(1):7444 |
1 | J:311143 Courtney JA, Wilson RL, Cnota J, Jones HN, Conditional Mutation of Hand1 in the Mouse Placenta Disrupts Placental Vascular Development Resulting in Fetal Loss in Both Early and Late Pregnancy. Int J Mol Sci. 2021 Sep 2;22(17) |
1 | J:237201 Espinosa-Medina I, Saha O, Boismoreau F, Chettouh Z, Rossi F, Richardson WD, Brunet JF, The sacral autonomic outflow is sympathetic. Science. 2016 Nov 18;354(6314):893-897 |
1* | J:92209 Huang F, Wagner M, Siddiqui MA, Ablation of the CLP-1 gene leads to down-regulation of the HAND1 gene and abnormality of the left ventricle of the heart and fetal death. Mech Dev. 2004 Jun;121(6):559-72 |
1 | J:357469 Sivori M, Dempsey B, Chettouh Z, Boismoreau F, Ayerdi M, et al., The pelvic organs receive no parasympathetic innervation. Elife. 2024;15 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
1* | J:152859 Varadkar PA, Kraman M, McCright B, Generation of mice that conditionally express the activation domain of Notch2. Genesis. 2009 Aug;47(8):573-8 |
Hand2 heart and neural crest derivatives expressed 2 (Synonyms: bHLHa26, dHAND, Ehand2, Hed, Thing2) | |
Results | Reference |
1* | J:162064 Abe M, Michikami I, Fukushi T, Abe A, Maeda Y, Ooshima T, Wakisaka S, Hand2 regulates chondrogenesis in vitro and in vivo. Bone. 2010 May;46(5):1359-68 |
1* | J:81037 Abe M, Tamamura Y, Yamagishi H, Maeda T, Kato J, Tabata MJ, Srivastava D, Wakisaka S, Kurisu K, Tooth-type specific expression of dHAND/Hand2: possible involvement in murine lower incisor morphogenesis. Cell Tissue Res. 2002 Nov;310(2):201-12 |
1 | J:303634 Arai Y, Ito M, Tanaka K, Ozawa J, Motojima Y, Matsuoka K, Igarashi K, Namba F, Increased expression of heme oxygenase-1 suppresses airway branching morphogenesis in fetal mouse lungs exposed to inflammation. Pediatr Res. 2020 Feb;87(3):494-500 |
1 | J:303643 Bi X, Wang K, Yang L, Pan H, Jiang H, Wei Q, Fang M, Yu H, Zhu C, Cai Y, He Y, Gan X, Zeng H, Yu D, Zhu Y, Jiang H, Qiu Q, Yang H, Zhang YE, Wang W, Zhu M, He S, Zhang G, Tracing the genetic footprints of vertebrate landing in non-teleost ray-finned fishes. Cell. 2021 Mar 4;184(5):1377-1391.e14 |
1 | J:332132 Cattaneo P, Hayes MGB, Baumgarten N, Hecker D, Peruzzo S, Aslan GS, Kunderfranco P, Larcher V, Zhang L, Contu R, Fonseca G, Spinozzi S, Chen J, Condorelli G, Dimmeler S, Schulz MH, Heinz S, Guimaraes-Camboa N, Evans SM, DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal. Nat Commun. 2022 Dec 2;13(1):7444 |
1 | J:166770 Coppola E, d'Autreaux F, Rijli FM, Brunet JF, Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation. Development. 2010 Dec;137(24):4211-20 |
1 | J:315113 Hafner R, Bohnenpoll T, Rudat C, Schultheiss TM, Kispert A, Fgfr2 is required for the expansion of the early adrenocortical primordium. Mol Cell Endocrinol. 2015 Sep 15;413:168-77 |
1* | J:278239 Han X, Zhang J, Liu Y, Fan X, Ai S, Luo Y, Li X, Jin H, Luo S, Zheng H, Yue Y, Chang Z, Yang Z, Tang F, He A, Shen X, The lncRNA Hand2os1/Uph locus orchestrates heart development through regulation of precise expression of Hand2. Development. 2019 Jul 4;146(13):dev176198 |
1 | J:332402 Hockman D, Adameyko I, Kaucka M, Barraud P, Otani T, Hunt A, Hartwig AC, Sock E, Waithe D, Franck MCM, Ernfors P, Ehinger S, Howard MJ, Brown N, Reese J, Baker CVH, Striking parallels between carotid body glomus cell and adrenal chromaffin cell development. Dev Biol. 2018 Dec 1;444 Suppl 1(Suppl 1):S308-S324 |
1* | J:92209 Huang F, Wagner M, Siddiqui MA, Ablation of the CLP-1 gene leads to down-regulation of the HAND1 gene and abnormality of the left ventricle of the heart and fetal death. Mech Dev. 2004 Jun;121(6):559-72 |
1 | J:79390 Huber K, Bruhl B, Guillemot F, Olson EN, Ernsberger U, Unsicker K, Development of chromaffin cells depends on MASH1 function. Development. 2002 Oct;129(20):4729-38 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
1 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
1* | J:93183 Ruest LB, Xiang X, Lim KC, Levi G, Clouthier DE, Endothelin-A receptor-dependent and -independent signaling pathways in establishing mandibular identity. Development. 2004 Sep;131(18):4413-23 |
1 | J:173638 Schmidt M, Huber L, Majdazari A, Schutz G, Williams T, Rohrer H, The transcription factors AP-2beta and AP-2alpha are required for survival of sympathetic progenitors and differentiated sympathetic neurons. Dev Biol. 2011 Jul 1;355(1):89-100 |
1 | J:208894 VanDusen NJ, Vincentz JW, Firulli BA, Howard MJ, Rubart M, Firulli AB, Loss of Hand2 in a population of Periostin lineage cells results in pronounced bradycardia and neonatal death. Dev Biol. 2014 Apr 15;388(2):149-58 |
1* | J:195264 Vincentz JW, Firulli BA, Lin A, Spicer DB, Howard MJ, Firulli AB, Twist1 Controls a Cell-Specification Switch Governing Cell Fate Decisions within the Cardiac Neural Crest. PLoS Genet. 2013 Mar;9(3):e1003405 |
Hand2os1 Hand2, opposite strand 1 (Synonyms: AV026068, Gm28063, Hand2-as1, Uph, upperhand) | |
Results | Reference |
1* | J:278239 Han X, Zhang J, Liu Y, Fan X, Ai S, Luo Y, Li X, Jin H, Luo S, Zheng H, Yue Y, Chang Z, Yang Z, Tang F, He A, Shen X, The lncRNA Hand2os1/Uph locus orchestrates heart development through regulation of precise expression of Hand2. Development. 2019 Jul 4;146(13):dev176198 |
Hapln1 hyaluronan and proteoglycan link protein 1 (Synonyms: cartilage linking protein 1, CLP, Crtl1, Crtl1l, link protein, LP-1) | |
Results | Reference |
1 | J:85802 Czipri M, Otto JM, Cs-Szabo G, Kamath RV, Vermes C, Firneisz G, Kolman KJ, Watanabe H, Li Y, Roughley PJ, Yamada Y, Olsen BR, Glant TT, Genetic rescue of chondrodysplasia and the perinatal lethal effect of cartilage link protein deficiency. J Biol Chem. 2003 Oct 3;278(40):39214-23 |
1 | J:347133 Funato N, Srivastava D, Shibata S, Yanagisawa H, TBX1 Regulates Chondrocyte Maturation in the Spheno-occipital Synchondrosis. J Dent Res. 2020 Sep;99(10):1182-1191 |
1 | J:159978 Gao Z, Kim GH, Mackinnon AC, Flagg AE, Bassett B, Earley JU, Svensson EC, Ets1 is required for proper migration and differentiation of the cardiac neural crest. Development. 2010 May;137(9):1543-51 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
Has2 hyaluronan synthase 2 | |
Results | Reference |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1 | J:160493 Dy P, Smits P, Silvester A, Penzo-Mendez A, Dumitriu B, Han Y, de la Motte CA, Kingsley DM, Lefebvre V, Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. Dev Biol. 2010 May 15;341(2):346-59 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:326033 Kim M, Koyama E, Saunders CM, Querido W, Pleshko N, Pacifici M, Synovial joint cavitation initiates with microcavities in interzone and is coupled to skeletal flexion and elongation in developing mouse embryo limbs. Biol Open. 2022 Jun 15;11(6):bio059381 |
1* | J:109568 Klewer SE, Yatskievych T, Pogreba K, Stevens MV, Antin PB, Camenisch TD, Has2 expression in heart forming regions is independent of BMP signaling. Gene Expr Patterns. 2006 Jun;6(5):462-70 |
1 | J:152912 Matsumoto K, Li Y, Jakuba C, Sugiyama Y, Sayo T, Okuno M, Dealy CN, Toole BP, Takeda J, Yamaguchi Y, Kosher RA, Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb. Development. 2009 Aug;136(16):2825-35 |
Hba hemoglobin alpha chain complex | |
Results | Reference |
1* | J:285404 Ueda T, Yokota T, Okuzaki D, Uno Y, Mashimo T, Kubota Y, Sudo T, Ishibashi T, Shingai Y, Doi Y, Ozawa T, Nakai R, Tanimura A, Ichii M, Ezoe S, Shibayama H, Oritani K, Kanakura Y, Endothelial Cell-Selective Adhesion Molecule Contributes to the Development of Definitive Hematopoiesis in the Fetal Liver. Stem Cell Reports. 2019 Dec 10;13(6):992-1005 |
Hba-a1 hemoglobin alpha, adult chain 1 (Synonyms: alpha 1 globin, Hba1) | |
Results | Reference |
3 | J:146606 Pritchard C, Mecham B, Dumpit R, Coleman I, Bhattacharjee M, Chen Q, Sikes RA, Nelson PS, Conserved gene expression programs integrate mammalian prostate development and tumorigenesis. Cancer Res. 2009 Mar 1;69(5):1739-47 |
1 | J:52217 Trimborn T, Gribnau J, Grosveld F, Fraser P, Mechanisms of developmental control of transcription in the murine alpha-and beta-globin loci. Genes Dev. 1999 Jan 1;13(1):112-24 |
Hba-a2 hemoglobin alpha, adult chain 2 (Synonyms: alpha 2 globin) | |
Results | Reference |
1 | J:52217 Trimborn T, Gribnau J, Grosveld F, Fraser P, Mechanisms of developmental control of transcription in the murine alpha-and beta-globin loci. Genes Dev. 1999 Jan 1;13(1):112-24 |
Hba-x hemoglobin X, alpha-like embryonic chain in Hba complex (Synonyms: zeta globin) | |
Results | Reference |
1* | J:271614 Gudmundsdottir B, Gudmundsson KO, Klarmann KD, Singh SK, Sun L, Singh S, Du Y, Coppola V, Stockwin L, Nguyen N, Tessarollo L, Thorsteinsson L, Sigurjonsson OE, Gudmundsson S, Rafnar T, Tisdale JF, Keller JR, POGZ Is Required for Silencing Mouse Embryonic beta-like Hemoglobin and Human Fetal Hemoglobin Expression. Cell Rep. 2018 Jun 12;23(11):3236-3248 |
1 | J:52217 Trimborn T, Gribnau J, Grosveld F, Fraser P, Mechanisms of developmental control of transcription in the murine alpha-and beta-globin loci. Genes Dev. 1999 Jan 1;13(1):112-24 |
1* | J:285404 Ueda T, Yokota T, Okuzaki D, Uno Y, Mashimo T, Kubota Y, Sudo T, Ishibashi T, Shingai Y, Doi Y, Ozawa T, Nakai R, Tanimura A, Ichii M, Ezoe S, Shibayama H, Oritani K, Kanakura Y, Endothelial Cell-Selective Adhesion Molecule Contributes to the Development of Definitive Hematopoiesis in the Fetal Liver. Stem Cell Reports. 2019 Dec 10;13(6):992-1005 |
Hbb-b1 hemoglobin, beta adult major chain (Synonyms: beta1, beta maj, beta major globin, MommeD7) | |
Results | Reference |
2* | J:190446 Brown FC, Scott N, Rank G, Collinge JE, Vadolas J, Vickaryous N, Whitelaw N, Whitelaw E, Kile BT, Jane SM, Curtis DJ, ENU mutagenesis identifies the first mouse mutants reproducing human beta-thalassemia at the genomic level. Blood Cells Mol Dis. 2013 Feb;50(2):86-92 |
1* | J:271614 Gudmundsdottir B, Gudmundsson KO, Klarmann KD, Singh SK, Sun L, Singh S, Du Y, Coppola V, Stockwin L, Nguyen N, Tessarollo L, Thorsteinsson L, Sigurjonsson OE, Gudmundsson S, Rafnar T, Tisdale JF, Keller JR, POGZ Is Required for Silencing Mouse Embryonic beta-like Hemoglobin and Human Fetal Hemoglobin Expression. Cell Rep. 2018 Jun 12;23(11):3236-3248 |
3 | J:146606 Pritchard C, Mecham B, Dumpit R, Coleman I, Bhattacharjee M, Chen Q, Sikes RA, Nelson PS, Conserved gene expression programs integrate mammalian prostate development and tumorigenesis. Cancer Res. 2009 Mar 1;69(5):1739-47 |
1 | J:239331 Smith EC, Luc S, Croney DM, Woodworth MB, Greig LC, Fujiwara Y, Nguyen M, Sher F, Macklis JD, Bauer DE, Orkin SH, Strict in vivo specificity of the Bcl11a erythroid enhancer. Blood. 2016 Oct 05;128(19):2338-2342 |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
1 | J:52217 Trimborn T, Gribnau J, Grosveld F, Fraser P, Mechanisms of developmental control of transcription in the murine alpha-and beta-globin loci. Genes Dev. 1999 Jan 1;13(1):112-24 |
1* | J:285404 Ueda T, Yokota T, Okuzaki D, Uno Y, Mashimo T, Kubota Y, Sudo T, Ishibashi T, Shingai Y, Doi Y, Ozawa T, Nakai R, Tanimura A, Ichii M, Ezoe S, Shibayama H, Oritani K, Kanakura Y, Endothelial Cell-Selective Adhesion Molecule Contributes to the Development of Definitive Hematopoiesis in the Fetal Liver. Stem Cell Reports. 2019 Dec 10;13(6):992-1005 |
Hbb-b2 hemoglobin, beta adult minor chain (Synonyms: beta2, beta min, beta minor globin) | |
Results | Reference |
1* | J:271614 Gudmundsdottir B, Gudmundsson KO, Klarmann KD, Singh SK, Sun L, Singh S, Du Y, Coppola V, Stockwin L, Nguyen N, Tessarollo L, Thorsteinsson L, Sigurjonsson OE, Gudmundsson S, Rafnar T, Tisdale JF, Keller JR, POGZ Is Required for Silencing Mouse Embryonic beta-like Hemoglobin and Human Fetal Hemoglobin Expression. Cell Rep. 2018 Jun 12;23(11):3236-3248 |
1 | J:239331 Smith EC, Luc S, Croney DM, Woodworth MB, Greig LC, Fujiwara Y, Nguyen M, Sher F, Macklis JD, Bauer DE, Orkin SH, Strict in vivo specificity of the Bcl11a erythroid enhancer. Blood. 2016 Oct 05;128(19):2338-2342 |
1 | J:52217 Trimborn T, Gribnau J, Grosveld F, Fraser P, Mechanisms of developmental control of transcription in the murine alpha-and beta-globin loci. Genes Dev. 1999 Jan 1;13(1):112-24 |
Hbb-bh1 hemoglobin Z, beta-like embryonic chain (Synonyms: betaH1, beta Hl globin) | |
Results | Reference |
1* | J:271614 Gudmundsdottir B, Gudmundsson KO, Klarmann KD, Singh SK, Sun L, Singh S, Du Y, Coppola V, Stockwin L, Nguyen N, Tessarollo L, Thorsteinsson L, Sigurjonsson OE, Gudmundsson S, Rafnar T, Tisdale JF, Keller JR, POGZ Is Required for Silencing Mouse Embryonic beta-like Hemoglobin and Human Fetal Hemoglobin Expression. Cell Rep. 2018 Jun 12;23(11):3236-3248 |
1 | J:239331 Smith EC, Luc S, Croney DM, Woodworth MB, Greig LC, Fujiwara Y, Nguyen M, Sher F, Macklis JD, Bauer DE, Orkin SH, Strict in vivo specificity of the Bcl11a erythroid enhancer. Blood. 2016 Oct 05;128(19):2338-2342 |
1 | J:52217 Trimborn T, Gribnau J, Grosveld F, Fraser P, Mechanisms of developmental control of transcription in the murine alpha-and beta-globin loci. Genes Dev. 1999 Jan 1;13(1):112-24 |
Hbb-y hemoglobin Y, beta-like embryonic chain (Synonyms: epsilon Y globin, Ey, Hby) | |
Results | Reference |
1* | J:271614 Gudmundsdottir B, Gudmundsson KO, Klarmann KD, Singh SK, Sun L, Singh S, Du Y, Coppola V, Stockwin L, Nguyen N, Tessarollo L, Thorsteinsson L, Sigurjonsson OE, Gudmundsson S, Rafnar T, Tisdale JF, Keller JR, POGZ Is Required for Silencing Mouse Embryonic beta-like Hemoglobin and Human Fetal Hemoglobin Expression. Cell Rep. 2018 Jun 12;23(11):3236-3248 |
1 | J:239331 Smith EC, Luc S, Croney DM, Woodworth MB, Greig LC, Fujiwara Y, Nguyen M, Sher F, Macklis JD, Bauer DE, Orkin SH, Strict in vivo specificity of the Bcl11a erythroid enhancer. Blood. 2016 Oct 05;128(19):2338-2342 |
1 | J:52217 Trimborn T, Gribnau J, Grosveld F, Fraser P, Mechanisms of developmental control of transcription in the murine alpha-and beta-globin loci. Genes Dev. 1999 Jan 1;13(1):112-24 |
1* | J:285404 Ueda T, Yokota T, Okuzaki D, Uno Y, Mashimo T, Kubota Y, Sudo T, Ishibashi T, Shingai Y, Doi Y, Ozawa T, Nakai R, Tanimura A, Ichii M, Ezoe S, Shibayama H, Oritani K, Kanakura Y, Endothelial Cell-Selective Adhesion Molecule Contributes to the Development of Definitive Hematopoiesis in the Fetal Liver. Stem Cell Reports. 2019 Dec 10;13(6):992-1005 |
Hbegf heparin-binding EGF-like growth factor (Synonyms: Dtr, HB-EGF, Hegfl) | |
Results | Reference |
1* | J:130339 Minami S, Iwamoto R, Mekada E, HB-EGF decelerates cell proliferation synergistically with TGFalpha in perinatal distal lung development. Dev Dyn. 2008 Jan;237(1):247-58 |
1 | J:124878 Sierro F, Biben C, Martinez-Munoz L, Mellado M, Ransohoff RM, Li M, Woehl B, Leung H, Groom J, Batten M, Harvey RP, Martinez-A C, Mackay CR, Mackay F, Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14759-64 |
Hbp1 high mobility group box transcription factor 1 (Synonyms: 1700058O05Rik, C330012F01Rik, C86454) | |
Results | Reference |
2* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
Hbs1l Hbs1-like (S. cerevisiae) (Synonyms: 2810035F15Rik, eRFS) | |
Results | Reference |
1 | J:306384 Terrey M, Adamson SI, Chuang JH, Ackerman SL, Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology. Elife. 2021 Apr 26;10:e66904 |
Hcfc1 host cell factor C1 (Synonyms: HCF-1, HCF1, VP16 accessory protein) | |
Results | Reference |
2 | J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134 |
1* | J:358134 Soma S, Murakami K, Fukuchi Y, Kunimoto H, Nakajima H, O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. Stem Cells. 2024 Jan 13;42(1):55-63 |
Hck hemopoietic cell kinase (Synonyms: Bmk, Hck-1) | |
Results | Reference |
1 | J:296737 Matsuura VKSK, Yoshida CA, Komori H, Sakane C, Yamana K, Jiang Q, Komori T, Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice. Int J Mol Sci. 2020 Apr 12;21(8):2682 |
1* | J:55945 Wang JP, Chuang SM, Shen CL, Chen ST, Expression of Src family during development of the mouse nervous system. Biomed Res. 1998 OCT;19(5):315-325 |
Hcn1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 (Synonyms: Bcng1, C630013B14Rik, HAC2, hyperpolarization-activated, cyclic nucleotide-gated K+ 1) | |
Results | Reference |
1 | J:250657 Greulich F, Trowe MO, Leffler A, Stoetzer C, Farin HF, Kispert A, Misexpression of Tbx18 in cardiac chambers of fetal mice interferes with chamber-specific developmental programs but does not induce a pacemaker-like gene signature. J Mol Cell Cardiol. 2016 Aug;97:140-9 |
Hcn4 hyperpolarization-activated, cyclic nucleotide-gated K+ 4 | |
Results | Reference |
1 | J:277168 Bohuslavova R, Cerychova R, Papousek F, Olejnickova V, Bartos M, Gorlach A, Kolar F, Sedmera D, Semenza GL, Pavlinkova G, HIF-1alpha is required for development of the sympathetic nervous system. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13414-13423 |
2 | J:330742 Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM, In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022 Oct 17;132(20):e156955 |
2* | J:306155 Goodyer WR, Beyersdorf BM, Paik DT, Tian L, Li G, Buikema JW, Chirikian O, Choi S, Venkatraman S, Adams EL, Tessier-Lavigne M, Wu JC, Wu SM, Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution. Circ Res. 2019 Aug 2;125(4):379-397 |
1 | J:250657 Greulich F, Trowe MO, Leffler A, Stoetzer C, Farin HF, Kispert A, Misexpression of Tbx18 in cardiac chambers of fetal mice interferes with chamber-specific developmental programs but does not induce a pacemaker-like gene signature. J Mol Cell Cardiol. 2016 Aug;97:140-9 |
1 | J:224301 Harris JP, Bhakta M, Bezprozvannaya S, Wang L, Lubczyk C, Olson EN, Munshi NV, MyoR modulates cardiac conduction by repressing Gata4. Mol Cell Biol. 2015 Feb;35(4):649-61 |
1 | J:192707 He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, Pu WT, Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res. 2012 Feb 3;110(3):406-15 |
1 | J:204126 Liang X, Wang G, Lin L, Lowe J, Zhang Q, Bu L, Chen Y, Chen J, Sun Y, Evans SM, HCN4 dynamically marks the first heart field and conduction system precursors. Circ Res. 2013 Aug 2;113(4):399-407 |
1 | J:226315 Ye W, Wang J, Song Y, Yu D, Sun C, Liu C, Chen F, Zhang Y, Wang F, Harvey RP, Schrader L, Martin JF, Chen Y, A common Shox2-Nkx2-5 antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node. Development. 2015 Jul 15;142(14):2521-32 |
Hdac1 histone deacetylase 1 (Synonyms: HD1, MommeD5, RPD3) | |
Results | Reference |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
3* | J:268084 Saha A, Tiwari S, Dharmarajan S, Otteson DC, Belecky-Adams TL, Class I histone deacetylases in retinal progenitors and differentiating ganglion cells. Gene Expr Patterns. 2018 Dec;30:37-48 |
2 | J:278287 Tang T, Zhang Y, Wang Y, Cai Z, Lu Z, Li L, Huang R, Hagelkruys A, Matthias P, Zhang H, Seiser C, Xie Y, HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development. Neuron. 2019 Mar 20;101(6):1117-1133.e5 |
Hdac2 histone deacetylase 2 (Synonyms: D10Wsu179e, Yy1bp) | |
Results | Reference |
1 | J:251599 Chen W, Chen L, Zhang Z, Meng F, Huang G, Sheng P, Zhang Z, Liao W, MicroRNA-455-3p modulates cartilage development and degeneration through modification of histone H3 acetylation. Biochim Biophys Acta. 2016 Dec;1863(12):2881-2891 |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
3* | J:268084 Saha A, Tiwari S, Dharmarajan S, Otteson DC, Belecky-Adams TL, Class I histone deacetylases in retinal progenitors and differentiating ganglion cells. Gene Expr Patterns. 2018 Dec;30:37-48 |
2 | J:278287 Tang T, Zhang Y, Wang Y, Cai Z, Lu Z, Li L, Huang R, Hagelkruys A, Matthias P, Zhang H, Seiser C, Xie Y, HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development. Neuron. 2019 Mar 20;101(6):1117-1133.e5 |
1* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
1* | J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903 |
Hdac3 histone deacetylase 3 | |
Results | Reference |
1 | J:251599 Chen W, Chen L, Zhang Z, Meng F, Huang G, Sheng P, Zhang Z, Liao W, MicroRNA-455-3p modulates cartilage development and degeneration through modification of histone H3 acetylation. Biochim Biophys Acta. 2016 Dec;1863(12):2881-2891 |
1 | J:306873 Li L, Jin J, Yang XJ, Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells. iScience. 2019 Oct 25;20:148-167 |
3* | J:268084 Saha A, Tiwari S, Dharmarajan S, Otteson DC, Belecky-Adams TL, Class I histone deacetylases in retinal progenitors and differentiating ganglion cells. Gene Expr Patterns. 2018 Dec;30:37-48 |
1 | J:297718 Szigety KM, Liu F, Yuan CY, Moran DJ, Horrell J, Gochnauer HR, Cohen RN, Katz JP, Kaestner KH, Seykora JT, Tobias JW, Lazar MA, Xu M, Millar SE, HDAC3 ensures stepwise epidermal stratification via NCoR/SMRT-reliant mechanisms independent of its histone deacetylase activity. Genes Dev. 2020 Jul 1;34(13-14):973-988 |
1 | J:233746 Wang X, Wang Y, Snitow ME, Stewart KM, Li S, Lu M, Morrisey EE, Expression of histone deacetylase 3 instructs alveolar type I cell differentiation by regulating a Wnt signaling niche in the lung. Dev Biol. 2016 Jun 15;414(2):161-9 |
1 | J:294983 Yao Y, Liu Q, Adrianto I, Wu X, Glassbrook J, Khalasawi N, Yin C, Yi Q, Dong Z, Geissmann F, Zhou L, Mi QS, Histone deacetylase 3 controls lung alveolar macrophage development and homeostasis. Nat Commun. 2020 Jul 30;11(1):3822 |
Hdac4 histone deacetylase 4 (Synonyms: 4932408F19Rik) | |
Results | Reference |
1 | J:131962 Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ, Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2111-6 |
1* | J:311442 Chen W, Sheng P, Huang Z, Meng F, Kang Y, Huang G, Zhang Z, Liao W, Zhang Z, MicroRNA-381 Regulates Chondrocyte Hypertrophy by Inhibiting Histone Deacetylase 4 Expression. Int J Mol Sci. 2016 Aug 23;17(9):1377 |
1 | J:321579 Ha N, Sun J, Bian Q, Wu D, Wang X, Hdac4 Regulates the Proliferation of Neural Crest-Derived Osteoblasts During Murine Craniofacial Development. Front Physiol. 2022;13:819619 |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
Hdac5 histone deacetylase 5 (Synonyms: mHDA1, mKIAA0600) | |
Results | Reference |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
Hdac6 histone deacetylase 6 (Synonyms: mHDA2, Sfc6) | |
Results | Reference |
1 | J:317613 Patnaik SR, Kretschmer V, Brucker L, Schneider S, Volz AK, Oancea-Castillo LDR, May-Simera HL, Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation. Cell Mol Life Sci. 2019 Feb;76(4):757-775 |
Hdac8 histone deacetylase 8 (Synonyms: 2610007D20Rik) | |
Results | Reference |
1 | J:251599 Chen W, Chen L, Zhang Z, Meng F, Huang G, Sheng P, Zhang Z, Liao W, MicroRNA-455-3p modulates cartilage development and degeneration through modification of histone H3 acetylation. Biochim Biophys Acta. 2016 Dec;1863(12):2881-2891 |
3* | J:268084 Saha A, Tiwari S, Dharmarajan S, Otteson DC, Belecky-Adams TL, Class I histone deacetylases in retinal progenitors and differentiating ganglion cells. Gene Expr Patterns. 2018 Dec;30:37-48 |
Hdac9 histone deacetylase 9 (Synonyms: D030072B18Rik, Hdac7b, HDRP, Mitr) | |
Results | Reference |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
Hdc histidine decarboxylase (Synonyms: Hdc-a, Hdc-c, Hdc-e, Hdc-s, L-histidine decarboxylase) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Hdx highly divergent homeobox (Synonyms: D030011N01Rik) | |
Results | Reference |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
Helt helt bHLH transcription factor (Synonyms: Heslike, megane) | |
Results | Reference |
1 | J:110708 Guimera J, Vogt Weisenhorn D, Echevarria D, Martinez S, Wurst W, Molecular characterization, structure and developmental expression of Megane bHLH factor. Gene. 2006 Aug 1;377:65-76 |
Herc2 HECT and RLD domain containing E3 ubiquitin protein ligase 2 (Synonyms: D15F32S1h, D7H15F32S1, D7H15F37S1, jdf2, rjs) | |
Results | Reference |
1* | J:56827 Walkowicz M, Ji Y, Ren X, Horsthemke B, Russell LB, Johnson D , Rinchik EM , Nicholls RD , Stubbs L, Molecular characterization of radiation- and chemically induced mutations associated with neuromuscular tremors, runting, juvenile lethality, and sperm defects in jdf2 mice. Mamm Genome. 1999 Sep;10(9):870-8 |
Hes1 hes family bHLH transcription factor 1 (Synonyms: bHLHb39, Hry) | |
Results | Reference |
1 | J:60107 Allen T, Lobe CG, A comparison of Notch, Hes and Grg expression during murine embryonic and post-natal development. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):687-708 |
1 | J:226612 Bankaitis ED, Bechard ME, Wright CV, Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche. Genes Dev. 2015 Oct 15;29(20):2203-16 |
1 | J:180979 Besnard V, Wert SE, Ikegami M, Xu Y, Heffner C, Murray SA, Donahue LR, Whitsett JA, Maternal synchronization of gestational length and lung maturation. PLoS One. 2011;6(11):e26682 |
1 | J:287985 Bosze B, Moon MS, Kageyama R, Brown NL, Simultaneous Requirements for Hes1 in Retinal Neurogenesis and Optic Cup-Stalk Boundary Maintenance. J Neurosci. 2020 Feb 12;40(7):1501-1513 |
1 | J:341148 Bosze B, Suarez-Navarro J, Cajias I, Brzezinski Iv JA, Brown NL, Notch pathway mutants do not equivalently perturb mouse embryonic retinal development. PLoS Genet. 2023 Sep;19(9):e1010928 |
1* | J:171072 Carre A, Rachdi L, Tron E, Richard B, Castanet M, Schlumberger M, Bidart JM, Szinnai G, Polak M, Hes1 is required for appropriate morphogenesis and differentiation during mouse thyroid gland development. PLoS One. 2011;6(2):e16752 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1 | J:91818 Collins BJ, Kleeberger W, Ball DW, Notch in lung development and lung cancer. Semin Cancer Biol. 2004 Oct;14(5):357-64 |
1 | J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109 |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1 | J:176609 Goldberg LB, Aujla PK, Raetzman LT, Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis. Dev Biol. 2011 Oct 1;358(1):23-32 |
1* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1 | J:237540 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R, The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development. 2016 Nov 15;143(22):4182-4192 |
1 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
1 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:166890 Hofmann JJ, Zovein AC, Koh H, Radtke F, Weinmaster G, Iruela-Arispe ML, Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome. Development. 2010 Dec;137(23):4061-72 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:64088 Ito T, Udaka N, Yazawa T, Okudela K, Hayashi H, Sudo T, Guillemot F, Kageyama R, Kitamura H, Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development. 2000 Sep;127(18):3913-21 |
1 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
1* | J:35621 Koop KE, MacDonald LM, Lobe CG, Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development. Mech Dev. 1996 Sep;59(1):73-87 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1 | J:195630 Krolewski RC, Packard A, Jang W, Wildner H, Schwob JE, Ascl1 (Mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium. PLoS One. 2012;7(12):e51737 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:237537 Liu C, Rodriguez K, Yao HH, Mapping lineage progression of somatic progenitor cells in the mouse fetal testis. Development. 2016 Oct 15;143(20):3700-3710 |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1 | J:214082 Maurer KA, Riesenberg AN, Brown NL, Notch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina. Development. 2014 Aug;141(16):3243-54 |
1 | J:320686 Molina LM, Zhu J, Li Q, Pradhan-Sundd T, Krutsenko Y, Sayed K, Jenkins N, Vats R, Bhushan B, Ko S, Hu S, Poddar M, Singh S, Tao J, Sundd P, Singhi A, Watkins S, Ma X, Benos PV, Feranchak A, Michalopoulos G, Nejak-Bowen K, Watson A, Bell A, Monga SP, Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors. Cell Rep. 2021 Jul 6;36(1):109310 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
1 | J:285050 Ochi S, Imaizumi Y, Shimojo H, Miyachi H, Kageyama R, Oscillatory expression of Hes1 regulates cell proliferation and neuronal differentiation in the embryonic brain. Development. 2020 Feb 26;147(4):dev182204 |
1 | J:173538 Packard A, Schnittke N, Romano RA, Sinha S, Schwob JE, {Delta}Np63 regulates stem cell dynamics in the Mammalian olfactory epithelium. J Neurosci. 2011 Jun 15;31(24):8748-59 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
2 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:255488 Premarathne S, Murtaza M, Matigian N, Jolly LA, Wood SA, Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors. Sci Rep. 2017 Aug 14;7(1):8109 |
1* | J:122509 Raetzman LT, Cai JX, Camper SA, Hes1 is required for pituitary growth and melanotrope specification. Dev Biol. 2007 Apr 15;304(2):455-66 |
1 | J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77 |
1 | J:284150 Roberts RR, Bobzin L, Teng CS, Pal D, Tuzon CT, Schweitzer R, Merrill AE, FGF signaling patterns cell fate at the interface between tendon and bone. Development. 2019 Aug 2;146(15):dev170241 |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
2 | J:320173 Traustadottir GA, Jensen CH, Thomassen M, Beck HC, Mortensen SB, Laborda J, Baladron V, Sheikh SP, Andersen DC, Evidence of non-canonical NOTCH signaling: Delta-like 1 homolog (DLK1) directly interacts with the NOTCH1 receptor in mammals. Cell Signal. 2016 Apr;28(4):246-54 |
2 | J:96850 van Tuyl M, Groenman F, Kuliszewski M, Ridsdale R, Wang J, Tibboel D, Post M, Overexpression of lunatic fringe does not affect epithelial cell differentiation in the developing mouse lung. Am J Physiol Lung Cell Mol Physiol. 2005 Apr;288(4):L672-82 |
1 | J:213069 Vanorny DA, Prasasya RD, Chalpe AJ, Kilen SM, Mayo KE, Notch signaling regulates ovarian follicle formation and coordinates follicular growth. Mol Endocrinol. 2014 Apr;28(4):499-511 |
1 | J:236342 Wang W, Jossin Y, Chai G, Lien WH, Tissir F, Goffinet AM, Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun. 2016 Mar 04;7:10936 |
1 | J:313628 Xi L, Carroll T, Matos I, Luo JD, Polak L, Pasolli HA, Jaffrey SR, Fuchs E, m6A RNA methylation impacts fate choices during skin morphogenesis. Elife. 2020 Aug 26;9:e56980 |
2 | J:325764 Xia Y, Zhang Y, Xu M, Zou X, Gao J, Ji MH, Chen G, Presenilin enhancer 2 is crucial for the transition of apical progenitors into neurons but into not basal progenitors in the developing hippocampus. Development. 2022 May 15;149(10):dev200272 |
1 | J:316098 Zhao J, Lu P, Wan C, Huang Y, Cui M, Yang X, Hu Y, Zheng Y, Dong J, Wang M, Zhang S, Liu Z, Bian S, Wang X, Wang R, Ren S, Wang D, Yao Z, Chang G, Tang F, Zhao XY, Cell-fate transition and determination analysis of mouse male germ cells throughout development. Nat Commun. 2021 Nov 25;12(1):6839 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
2 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Hes2 hes family bHLH transcription factor 2 (Synonyms: HES-2) | |
Results | Reference |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
Hes3 hes family bHLH transcription factor 3 (Synonyms: bHLHb43) | |
Results | Reference |
1 | J:60107 Allen T, Lobe CG, A comparison of Notch, Hes and Grg expression during murine embryonic and post-natal development. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):687-708 |
1* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1* | J:39657 Lobe CG, Expression of the helix-loop-helix factor, Hes3, during embryo development suggests a role in early midbrain-hindbrain patterning. Mech Dev. 1997 Mar;62(2):227-37 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
Hes5 hes family bHLH transcription factor 5 (Synonyms: bHLHb38) | |
Results | Reference |
1 | J:341148 Bosze B, Suarez-Navarro J, Cajias I, Brzezinski Iv JA, Brown NL, Notch pathway mutants do not equivalently perturb mouse embryonic retinal development. PLoS Genet. 2023 Sep;19(9):e1010928 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:264143 Cheung L, Le Tissier P, Goldsmith SG, Treier M, Lovell-Badge R, Rizzoti K, NOTCH activity differentially affects alternative cell fate acquisition and maintenance. Elife. 2018 Mar 26;7:e33318 |
1 | J:218288 Falcone C, Filippis C, Granzotto M, Mallamaci A, Emx2 expression levels in NSCs modulate astrogenesis rates by regulating EgfR and Fgf9. Glia. 2015 Mar;63(3):412-22 |
1 | J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489 |
1* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1 | J:237540 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R, The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development. 2016 Nov 15;143(22):4182-4192 |
1 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
1 | J:117235 Hayashi T, Cunningham D, Bermingham-McDonogh O, Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti. Dev Dyn. 2007 Feb;236(2):525-33 |
1 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:159019 Imayoshi I, Sakamoto M, Yamaguchi M, Mori K, Kageyama R, Essential roles of Notch signaling in maintenance of neural stem cells in developing and adult brains. J Neurosci. 2010 Mar 3;30(9):3489-98 |
1 | J:64088 Ito T, Udaka N, Yazawa T, Okudela K, Hayashi H, Sudo T, Guillemot F, Kageyama R, Kitamura H, Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development. 2000 Sep;127(18):3913-21 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:135642 Li S, Mark S, Radde-Gallwitz K, Schlisner R, Chin MT, Chen P, Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development. BMC Dev Biol. 2008;8:20 |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1* | J:91057 Louvi A, Sisodia SS, Grove EA, Presenilin 1 in migration and morphogenesis in the central nervous system. Development. 2004 Jul;131(13):3093-105 |
1 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
1 | J:309437 Nakagawa N, Li J, Yabuno-Nakagawa K, Eom TY, Cowles M, Mapp T, Taylor R, Anton ES, APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017 Aug 15;31(16):1679-1692 |
1 | J:285050 Ochi S, Imaizumi Y, Shimojo H, Miyachi H, Kageyama R, Oscillatory expression of Hes1 regulates cell proliferation and neuronal differentiation in the embryonic brain. Development. 2020 Feb 26;147(4):dev182204 |
1* | J:359452 Pang Y, Ruan X, Liu W, Hou L, Yin B, Shu P, Peng X, MicroRNA-495 Modulates Neuronal Layer Fate Determination by Targeting Tcf4. Int J Biol Sci. 2024;20(15):6207-6221 |
1 | J:92098 Petersen PH, Zou K, Krauss S, Zhong W, Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis. Nat Neurosci. 2004 Aug;7(8):803-11 |
2 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:255488 Premarathne S, Murtaza M, Matigian N, Jolly LA, Wood SA, Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors. Sci Rep. 2017 Aug 14;7(1):8109 |
1 | J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77 |
1 | J:284150 Roberts RR, Bobzin L, Teng CS, Pal D, Tuzon CT, Schweitzer R, Merrill AE, FGF signaling patterns cell fate at the interface between tendon and bone. Development. 2019 Aug 2;146(15):dev170241 |
1 | J:187684 Rodriguez M, Choi J, Park S, Sockanathan S, Gde2 regulates cortical neuronal identity by controlling the timing of cortical progenitor differentiation. Development. 2012 Oct;139(20):3870-9 |
1* | J:310127 Ruan X, Liu G, Zhou J, Chen P, Sun C, Liu W, Wu C, Hou L, Yin B, Qiang B, Shu P, Peng X, Zbed3 Is Indispensable for Wnt Signaling Regulation of Cortical Layers Formation in Developing Brain. Cereb Cortex. 2021 Jul 29;31(9):4078-4091 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:112461 Tang LS, Alger HM, Pereira FA, COUP-TFI controls Notch regulation of hair cell and support cell differentiation. Development. 2006 Sep;133(18):3683-93 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:344966 Wei Y, Wang X, Ma Z, Xiang P, Liu G, Yin B, Hou L, Shu P, Liu W, Peng X, Sirt6 regulates the proliferation of neural precursor cells and cortical neurogenesis in mice. iScience. 2024 Feb 16;27(2):108706 |
2 | J:325764 Xia Y, Zhang Y, Xu M, Zou X, Gao J, Ji MH, Chen G, Presenilin enhancer 2 is crucial for the transition of apical progenitors into neurons but into not basal progenitors in the developing hippocampus. Development. 2022 May 15;149(10):dev200272 |
1* | J:314887 Zhang M, Zhou J, Jiao L, Xu L, Hou L, Yin B, Qiang B, Lu S, Shu P, Peng X, Long Non-coding RNA T-uc.189 Modulates Neural Progenitor Cell Fate by Regulating Srsf3 During Mouse Cerebral Cortex Development. Front Neurosci. 2021;15:709684 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Hes6 hairy and enhancer of split 6 (Synonyms: bHLHb41) | |
Results | Reference |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:135642 Li S, Mark S, Radde-Gallwitz K, Schlisner R, Chin MT, Chen P, Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development. BMC Dev Biol. 2008;8:20 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Hes7 hes family bHLH transcription factor 7 (Synonyms: bHLHb37) | |
Results | Reference |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:284150 Roberts RR, Bobzin L, Teng CS, Pal D, Tuzon CT, Schweitzer R, Merrill AE, FGF signaling patterns cell fate at the interface between tendon and bone. Development. 2019 Aug 2;146(15):dev170241 |
Hesx1 homeobox gene expressed in ES cells (Synonyms: HES-1, Rpx) | |
Results | Reference |
1* | J:73085 Dasen JS, Barbera JP, Herman TS, Connell SO, Olson L, Ju B, Tollkuhn J, Baek SH, Rose DW, Rosenfeld MG, Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 1;15(23):3193-207 |
Hey1 hairy/enhancer-of-split related with YRPW motif 1 (Synonyms: bHLHb31, CHF2, Herp2, hesr-1, Hesr1, HRT1) | |
Results | Reference |
1 | J:180979 Besnard V, Wert SE, Ikegami M, Xu Y, Heffner C, Murray SA, Donahue LR, Whitsett JA, Maternal synchronization of gestational length and lung maturation. PLoS One. 2011;6(11):e26682 |
1 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1 | J:176609 Goldberg LB, Aujla PK, Raetzman LT, Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis. Dev Biol. 2011 Oct 1;358(1):23-32 |
1* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1 | J:183603 Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A, Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res. 2011 Apr 1;108(7):813-23 |
1* | J:135657 Hayashi T, Kokubo H, Hartman BH, Ray CA, Reh TA, Bermingham-McDonogh O, Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea. Dev Biol. 2008 Apr 1;316(1):87-99 |
1 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1* | J:260416 Kibe K, Nakatomi M, Kataoka S, Toyono T, Seta Y, Hey1 and Hey2 are differently expressed during mouse tooth development. Gene Expr Patterns. 2018 Jan;27:99-105 |
1 | J:257613 Kuony A, Michon F, Epithelial Markers aSMA, Krt14, and Krt19 Unveil Elements of Murine Lacrimal Gland Morphogenesis and Maturation. Front Physiol. 2017;8:739 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:135642 Li S, Mark S, Radde-Gallwitz K, Schlisner R, Chin MT, Chen P, Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development. BMC Dev Biol. 2008;8:20 |
1 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
1 | J:114717 Raetzman LT, Wheeler BS, Ross SA, Thomas PQ, Camper SA, Persistent expression of Notch2 delays gonadotrope differentiation. Mol Endocrinol. 2006 Nov;20(11):2898-908 |
1 | J:180027 Restivo G, Nguyen BC, Dziunycz P, Ristorcelli E, Ryan RJ, Ozuysal OY, Di Piazza M, Radtke F, Dixon MJ, Hofbauer GF, Lefort K, Dotto GP, IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes. EMBO J. 2011 Nov 16;30(22):4571-85 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1 | J:269446 Salguero-Jimenez A, Grego-Bessa J, D'Amato G, Jimenez-Borreguero LJ, de la Pompa JL, Myocardial Notch1-Rbpj deletion does not affect NOTCH signaling, heart development or function. PLoS One. 2018;13(12):e0203100 |
1 | J:320173 Traustadottir GA, Jensen CH, Thomassen M, Beck HC, Mortensen SB, Laborda J, Baladron V, Sheikh SP, Andersen DC, Evidence of non-canonical NOTCH signaling: Delta-like 1 homolog (DLK1) directly interacts with the NOTCH1 receptor in mammals. Cell Signal. 2016 Apr;28(4):246-54 |
1 | J:299728 Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL, Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. Elife. 2019 Dec 4;8:e49977 |
1 | J:340444 Veithen M, Huyghe A, Van Den Ackerveken P, Fukada SI, Kokubo H, Breuskin I, Nguyen L, Delacroix L, Malgrange B, Sox9 Inhibits Cochlear Hair Cell Fate by Upregulating Hey1 and HeyL Antagonists of Atoh1. Cells. 2023 Aug 25;12(17) |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Hey2 hairy/enhancer-of-split related with YRPW motif 2 (Synonyms: bHLHb32, CHF1, Herp1, Hesr2, Hrt2) | |
Results | Reference |
1 | J:185237 Chen L, Ma Y, Kim EY, Yu W, Schwartz RJ, Qian L, Wang J, Conditional ablation of Ezh2 in murine hearts reveals its essential roles in endocardial cushion formation, cardiomyocyte proliferation and survival. PLoS One. 2012;7(2):e31005 |
2* | J:60859 Chin MT, Maemura K, Fukumoto S, Jain MK, Layne MD, Watanabe M, Hsieh CM, Lee ME, Cardiovascular basic helix loop helix factor 1, a novel transcriptional repressor expressed preferentially in the developing and adult cardiovascular system. J Biol Chem. 2000 Mar 3;275(9):6381-7 |
1 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1 | J:176609 Goldberg LB, Aujla PK, Raetzman LT, Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis. Dev Biol. 2011 Oct 1;358(1):23-32 |
1* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
1 | J:183603 Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A, Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res. 2011 Apr 1;108(7):813-23 |
1* | J:135657 Hayashi T, Kokubo H, Hartman BH, Ray CA, Reh TA, Bermingham-McDonogh O, Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea. Dev Biol. 2008 Apr 1;316(1):87-99 |
1* | J:260416 Kibe K, Nakatomi M, Kataoka S, Toyono T, Seta Y, Hey1 and Hey2 are differently expressed during mouse tooth development. Gene Expr Patterns. 2018 Jan;27:99-105 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:135642 Li S, Mark S, Radde-Gallwitz K, Schlisner R, Chin MT, Chen P, Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development. BMC Dev Biol. 2008;8:20 |
1 | J:195070 Luxan G, Casanova JC, Martinez-Poveda B, Prados B, D'Amato G, MacGrogan D, Gonzalez-Rajal A, Dobarro D, Torroja C, Martinez F, Izquierdo-Garcia JL, Fernandez-Friera L, Sabater-Molina M, Kong YY, Pizarro G, Ibanez B, Medrano C, Garcia-Pavia P, Gimeno JR,Monserrat L, Jimenez-Borreguero LJ, de la Pompa JL, Mutations in the NOTCH pathway regulator MIB1 cause left ventricular noncompaction cardiomyopathy. Nat Med. 2013 Feb;19(2):193-201 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
2* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1 | J:269446 Salguero-Jimenez A, Grego-Bessa J, D'Amato G, Jimenez-Borreguero LJ, de la Pompa JL, Myocardial Notch1-Rbpj deletion does not affect NOTCH signaling, heart development or function. PLoS One. 2018;13(12):e0203100 |
1 | J:338889 Siguero-Alvarez M, Salguero-Jimenez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sanchez-Saez F, Pineiro-Sabaris R, Felipe-Medina N, Torroja C, Gomez MJ, Sabater-Molina M, Escriba R, Richaud-Patin I, Iglesias-Garcia O, Sbroggio M, Callejas S, O'Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibanez B, Monserrat L, Perez-Pomares JM, Sanchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL, A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation. 2023 Jan 3;147(1):47-65 |
1 | J:320173 Traustadottir GA, Jensen CH, Thomassen M, Beck HC, Mortensen SB, Laborda J, Baladron V, Sheikh SP, Andersen DC, Evidence of non-canonical NOTCH signaling: Delta-like 1 homolog (DLK1) directly interacts with the NOTCH1 receptor in mammals. Cell Signal. 2016 Apr;28(4):246-54 |
1 | J:299728 Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL, Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. Elife. 2019 Dec 4;8:e49977 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
1 | J:213069 Vanorny DA, Prasasya RD, Chalpe AJ, Kilen SM, Mayo KE, Notch signaling regulates ovarian follicle formation and coordinates follicular growth. Mol Endocrinol. 2014 Apr;28(4):499-511 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Heyl hairy/enhancer-of-split related with YRPW motif-like (Synonyms: bHLHb33, Hesr3, Hey3, Hrt3) | |
Results | Reference |
1 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1 | J:176609 Goldberg LB, Aujla PK, Raetzman LT, Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis. Dev Biol. 2011 Oct 1;358(1):23-32 |
1* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1 | J:183603 Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A, Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res. 2011 Apr 1;108(7):813-23 |
1* | J:135657 Hayashi T, Kokubo H, Hartman BH, Ray CA, Reh TA, Bermingham-McDonogh O, Hesr1 and Hesr2 may act as early effectors of Notch signaling in the developing cochlea. Dev Biol. 2008 Apr 1;316(1):87-99 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:269446 Salguero-Jimenez A, Grego-Bessa J, D'Amato G, Jimenez-Borreguero LJ, de la Pompa JL, Myocardial Notch1-Rbpj deletion does not affect NOTCH signaling, heart development or function. PLoS One. 2018;13(12):e0203100 |
1 | J:299728 Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL, Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. Elife. 2019 Dec 4;8:e49977 |
1 | J:340444 Veithen M, Huyghe A, Van Den Ackerveken P, Fukada SI, Kokubo H, Breuskin I, Nguyen L, Delacroix L, Malgrange B, Sox9 Inhibits Cochlear Hair Cell Fate by Upregulating Hey1 and HeyL Antagonists of Atoh1. Cells. 2023 Aug 25;12(17) |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Hgf hepatocyte growth factor (Synonyms: C230052L06Rik, HGF/SF, NK1, NK2, scatter factor, SF/HGF) | |
Results | Reference |
1* | J:74504 Amano O, Yamane A, Shimada M, Koshimizu U, Nakamura T, Iseki S, Hepatocyte growth factor is essential for migration of myogenic cells and promotes their proliferation during the early periods of tongue morphogenesis in mouse embryos. Dev Dyn. 2002 Mar;223(2):169-79 |
1 | J:283675 Comai G, Heude E, Mella S, Paisant S, Pala F, Gallardo M, Langa F, Kardon G, Gopalakrishnan S, Tajbakhsh S, A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle. Elife. 2019 Sep 19;8:e47460 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:85916 Ikari T, Hiraki A, Seki K, Sugiura T, Matsumoto K, Shirasuna K, Involvement of hepatocyte growth factor in branching morphogenesis of murine salivary gland. Dev Dyn. 2003 Oct;228(2):173-84 |
1 | J:289321 Jangphattananont N, Sato H, Imamura R, Sakai K, Terakado Y, Murakami K, Barker N, Oshima H, Oshima M, Takagi J, Kato Y, Yano S, Matsumoto K, Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach. Int J Mol Sci. 2019 Jun 17;20(12):2955 |
2 | J:41235 Kaestner KH, Silberg DG, Traber PG, Schutz G, The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation. Genes Dev. 1997 Jun 15;11(12):1583-95 |
1 | J:289982 Morell RJ, Olszewski R, Tona R, Leitess S, Wafa TT, Taukulis I, Schultz JM, Thomason EJ, Richards K, Whitley BN, Hill C, Saunders T, Starost MF, Fitzgerald T, Wilson E, Ohyama T, Friedman TB, Hoa M, Noncoding Microdeletion in Mouse Hgf Disrupts Neural Crest Migration into the Stria Vascularis, Reduces the Endocochlear Potential, and Suggests the Neuropathology for Human Nonsyndromic Deafness DFNB39. J Neurosci. 2020 Apr 8;40(15):2976-2992 |
1* | J:60601 Otsuka T, Jakubczak J, Vieira W, Bottaro DP, Breckenridge D, Larochelle WJ, Merlino G, Disassociation of met-mediated biological responses in vivo: the natural hepatocyte growth factor/scatter factor splice variant NK2 antagonizes growth but facilitates metastasis. Mol Cell Biol. 2000 Mar;20(6):2055-65 |
2 | J:69135 Powell EM, Mars WM, Levitt P, Hepatocyte growth factor/scatter factor is a motogen for interneurons migrating from the ventral to dorsal telencephalon. Neuron. 2001 Apr;30(1):79-89 |
1 | J:247907 Yao J, Guihard PJ, Wu X, Blazquez-Medela AM, Spencer MJ, Jumabay M, Tontonoz P, Fogelman AM, Bostrom KI, Yao Y, Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. J Cell Biol. 2017 Oct 02;216(10):3369-3385 |
Hgs HGF-regulated tyrosine kinase substrate (Synonyms: Hrs, tn) | |
Results | Reference |
1* | J:339600 Hermosilla Aguayo V, Martin P, Tian N, Zheng J, Aho R, Losa M, Selleri L, ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42 |
Hhex hematopoietically expressed homeobox (Synonyms: Hex, Hex1, Hhex-rs2, Prhx) | |
Results | Reference |
1 | J:64542 Bogue CW, Ganea GR, Sturm E, Ianucci R, Jacobs HC, Hex expression suggests a role in the development and function of organs derived from foregut endoderm. Dev Dyn. 2000 Sep;219(1):84-9 |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1 | J:239946 Pan FC, Brissova M, Powers AC, Pfaff S, Wright CV, Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing beta-cells to a delta-like fate and reveals a facultative proliferative capacity in aged beta-cells. Development. 2015 Nov 01;142(21):3637-48 |
Hhip Hedgehog-interacting protein (Synonyms: Hhip1, Hip, Hip1) | |
Results | Reference |
1 | J:346119 Amano K, Okuzaki D, Kitaoka Y, Kato S, Fujiwara M, Tanaka S, Iida S, Pth1r in Neural Crest Cells Regulates Nasal Cartilage Differentiation. J Dent Res. 2024 Mar;103(3):308-317 |
1* | J:88802 Berman DM, Desai N, Wang X, Karhadkar SS, Reynon M, Abate-Shen C, Beachy PA, Shen MM, Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis. Dev Biol. 2004 Mar 15;267(2):387-98 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1 | J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132 |
1 | J:175769 Hsu SH, Zhang X, Yu C, Li ZJ, Wunder JS, Hui CC, Alman BA, Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu. Development. 2011 Sep;138(17):3791-801 |
1* | J:85472 Kawahira H, Ma NH, Tzanakakis ES, McMahon AP, Chuang PT, Hebrok M, Combined activities of hedgehog signaling inhibitors regulate pancreas development. Development. 2003 Oct;130(20):4871-9 |
1 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Hif1a hypoxia inducible factor 1, alpha subunit (Synonyms: bHLHe78, HIF-1alpha, HIF1alpha, MOP1) | |
Results | Reference |
1 | J:346910 Ayyangar U, Karkhanis A, Tay H, Afandi AFB, Bhattacharjee O, Ks L, Lee SH, Chan J, Raghavan S, Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin. EMBO J. 2024 Apr;43(7):1113-1134 |
2* | J:180152 Bridges JP, Lin S, Ikegami M, Shannon JM, Conditional hypoxia inducible factor-1alpha induction in embryonic pulmonary epithelium impairs maturation and augments lymphangiogenesis. Dev Biol. 2012 Feb 1;362(1):24-41 |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1* | J:331512 Kimura S, Takeshita N, Oyanagi T, Seki D, Jiang W, Hidaka K, Fukumoto S, Takahashi I, Takano-Yamamoto T, HIF-2alpha Inhibits Ameloblast Differentiation via Hey2 in Tooth Development. J Dent Res. 2022 Dec;101(13):1637-1644 |
1 | J:140565 Sakakura Y, Shibui T, Irie K, Yajima T, Metabolic mode peculiar to Meckel's cartilage: immunohistochemical comparisons of hypoxia-inducible factor-1alpha and glucose transporters in developing endochondral bones in mice. Eur J Oral Sci. 2008 Jul;116(4):341-52 |
Hif3a hypoxia inducible factor 3, alpha subunit (Synonyms: bHLHe17, MOP7, Nepas) | |
Results | Reference |
1* | J:180152 Bridges JP, Lin S, Ikegami M, Shannon JM, Conditional hypoxia inducible factor-1alpha induction in embryonic pulmonary epithelium impairs maturation and augments lymphangiogenesis. Dev Biol. 2012 Feb 1;362(1):24-41 |
1 | J:132655 Yamashita T, Ohneda O, Nagano M, Iemitsu M, Makino Y, Tanaka H, Miyauchi T, Goto K, Ohneda K, Fujii-Kuriyama Y, Poellinger L, Yamamoto M, Abnormal heart development and lung remodeling in mice lacking the hypoxia-inducible factor-related basic helix-loop-helix PAS protein NEPAS. Mol Cell Biol. 2008 Feb;28(4):1285-97 |
Hikeshi heat shock protein nuclear import factor (Synonyms: 0610007P06Rik, 1110002N09Rik, Hikeshi, l(7)6Rn, l7Rn6) | |
Results | Reference |
2* | J:105164 Fernandez-Valdivia R, Zhang Y, Pai S, Metzker ML, Schumacher A, l7Rn6 Encodes a Novel Protein Required for Clara Cell Function in Mouse Lung Development. Genetics. 2006 Jan;172(1):389-99 |
Hipk1 homeodomain interacting protein kinase 1 (Synonyms: 1110062K04Rik, Myak) | |
Results | Reference |
1 | J:60697 Shang E, Wang X, Huang J, Yoshida W, Kuroiwa A, Wolgemuth DJ, Murine Myak, a member of a family of yeast YAK1-related genes, is highly expressed in hormonally modulated epithelia in the reproductive system and in the embryonic central nervous system. Mol Reprod Dev. 2000 Apr;55(4):372-8 |
Hipk2 homeodomain interacting protein kinase 2 (Synonyms: 1110014O20Rik, B230339E18Rik, Stank) | |
Results | Reference |
2* | J:74769 Pierantoni GM, Bulfone A, Pentimalli F, Fedele M, Iuliano R, Santoro M, Chiariotti L, Ballabio A, Fusco A, The homeodomain-interacting protein kinase 2 gene is expressed late in embryogenesis and preferentially in retina, muscle, and neural tissues. Biochem Biophys Res Commun. 2002 Jan 25;290(3):942-7 |
Hivep1 human immunodeficiency virus type I enhancer binding protein 1 (Synonyms: alphaA-CRYBP1, Cryabp1) | |
Results | Reference |
1* | J:62593 Tanaka K, Matsumoto Y, Nakatani F, Iwamoto Y, Yamada Y, A zinc finger transcription factor, alphaA-crystallin binding protein 1, is a negative regulator of the chondrocyte-specific enhancer of the alpha1(II) collagen gene. (Retraction and replacement of Figures 1D and 7 appear in 2006; 26(13):5202). Mol Cell Biol. 2000 Jun;20(12):4428-35 |
Hivep2 human immunodeficiency virus type I enhancer binding protein 2 (Synonyms: Gm20114, MIBP1, Schnurri-2, Shn-2) | |
Results | Reference |
2* | J:87280 Campbell DB, Levitt P, Regionally restricted expression of the transcription factor c-myc intron 1 binding protein during brain development. J Comp Neurol. 2003 Dec 22;467(4):581-92 |
Hivep3 human immunodeficiency virus type I enhancer binding protein 3 (Synonyms: 2900056N03Rik, E030045D18Rik, Krc, Schnurri-3, Shn3) | |
Results | Reference |
2* | J:77246 Hicar MD, Robinson ML, Wu LC, Embryonic expression and regulation of the large zinc finger protein KRC. Genesis. 2002 May;33(1):8-20 |
Hjv hemojuvelin BMP co-receptor (Synonyms: 2310035L15Rik, 5230400G09Rik, DL-M, hemojuvelin, Hfe2, HJV, Rgmc) | |
Results | Reference |
1* | J:87768 Niederkofler V, Salie R, Sigrist M, Arber S, Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. J Neurosci. 2004 Jan 28;24(4):808-18 |
Hk1 hexokinase 1 (Synonyms: Hk-1, Hk1-s, mHk1-s) | |
Results | Reference |
2* | J:132397 Cifuentes D, Martinez-Pons C, Garcia-Rocha M, Galina A, de Pouplana LR, Guinovart JJ, Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver. J Biol Chem. 2008 Feb 29;283(9):5642-9 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
Hk2 hexokinase 2 (Synonyms: HKII) | |
Results | Reference |
2* | J:132397 Cifuentes D, Martinez-Pons C, Garcia-Rocha M, Galina A, de Pouplana LR, Guinovart JJ, Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver. J Biol Chem. 2008 Feb 29;283(9):5642-9 |
1* | J:314146 Gao W, Zhang Y, Luo H, Niu M, Zheng X, Hu W, Cui J, Xue X, Bo Y, Dai F, Lu Y, Yang D, Guo Y, Guo H, Li H, Zhang Y, Yang T, Li L, Zhang L, Hou R, Wen S, An C, Ma T, Jin L, Xu W, Wu Y, Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis. Cell Death Dis. 2020 Oct 26;11(10):919 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
Hltf helicase-like transcription factor (Synonyms: P113, Smarca3, Snf2l3) | |
Results | Reference |
1* | J:330216 Li J, Cheng C, Xu J, Zhang T, Tokat B, Dolios G, Ramakrishnan A, Shen L, Wang R, Xu PX, The transcriptional coactivator Eya1 exerts transcriptional repressive activity by interacting with REST corepressors and REST-binding sequences to maintain nephron progenitor identity. Nucleic Acids Res. 2022 Oct 14;50(18):10343-10359 |
1* | J:252991 Sandhu S, Wu X, Nabi Z, Rastegar M, Kung S, Mai S, Ding H, Loss of HLTF function promotes intestinal carcinogenesis. Mol Cancer. 2012 Mar 27;11:18 |
Hlx H2.0-like homeobox (Synonyms: Hlx1) | |
Results | Reference |
1* | J:11076 Allen JD, Lints T, Jenkins NA, Copeland NG, Strasser A, Harvey RP, Adams JM, Novel murine homeo box gene on chromosome 1 expressed in specific hematopoietic lineages and during embryogenesis. Genes Dev. 1991 Apr;5(4):509-20 |
Hmcn1 hemicentin 1 (Synonyms: EG545370, LOC240793) | |
Results | Reference |
1* | J:310857 Welcker D, Stein C, Feitosa NM, Armistead J, Zhang JL, Lutke S, Kleinridders A, Bruning JC, Eming SA, Sengle G, Niehoff A, Bloch W, Hammerschmidt M, Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions. Sci Rep. 2021 Sep 9;11(1):17926 |
Hmcn2 hemicentin 2 (Synonyms: MGC:31312, MGC:49669) | |
Results | Reference |
1* | J:310857 Welcker D, Stein C, Feitosa NM, Armistead J, Zhang JL, Lutke S, Kleinridders A, Bruning JC, Eming SA, Sengle G, Niehoff A, Bloch W, Hammerschmidt M, Hemicentin-1 is an essential extracellular matrix component of the dermal-epidermal and myotendinous junctions. Sci Rep. 2021 Sep 9;11(1):17926 |
Hmg20a high mobility group 20A (Synonyms: 1200004E06Rik, 5730490E10Rik, Hmgxb1, iBRAF) | |
Results | Reference |
1* | J:359190 Nagai M, Porter RS, Miyasato M, Wang A, Gavilan CM, Hughes ED, Wu MC, Saunders TL, Iwase S, Neuronal splicing of the unmethylated histone H3K4 reader, PHF21A, prevents excessive synaptogenesis. J Biol Chem. 2024 Nov;300(11):107881 |
1 | J:331893 Yang J, Zhang L, Li Y, Chen M, Identifying key m(6)A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses. Front Genet. 2022;13:974357 |
Hmg20b high mobility group 20B (Synonyms: BRAF35, BRCA2-associated factor 35, Hmgx2, Hmgxb2, Smarce1r) | |
Results | Reference |
1* | J:359190 Nagai M, Porter RS, Miyasato M, Wang A, Gavilan CM, Hughes ED, Wu MC, Saunders TL, Iwase S, Neuronal splicing of the unmethylated histone H3K4 reader, PHF21A, prevents excessive synaptogenesis. J Biol Chem. 2024 Nov;300(11):107881 |
1* | J:55356 Wattler F, Wattler S, Kelly M, Skinner HB, Nehls M, Cloning, chromosomal location and expression analysis of murine Smarce1-related, a new member of the high-mobility 365 group gene family. Genomics. 1999 Sep 1;60(2):172-178 |
Hmga1 high mobility group AT-hook 1 (Synonyms: Hmga1a, Hmga1b, Hmgi, Hmgiy, HMG-I(Y), HMGI(Y), HMGY) | |
Results | Reference |
1* | J:74341 Schiltz JF, Kesari K, Ashar HR, Chada K, Hmgi-c-independent Activation of MuRantes in Vivo. Cell Growth Differ. 2002 Jan;13(1):39-45 |
1* | J:28571 Zhou X, Benson KF, Ashar HR, Chada K, Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C [see comments]. Nature. 1995 Aug 31;376(6543):771-4 |
Hmga2 high mobility group AT-hook 2 (Synonyms: 9430083A20Rik, Hmgic, HMGI-C) | |
Results | Reference |
1* | J:118604 D'Armiento J, Imai K, Schiltz J, Kolesnekova N, Sternberg D, Benson K, Pardo A, Selman M, Smolarek T, Vundavalli M, Sonnet J, Szabolcs M, Chada K, Identification of the benign mesenchymal tumor gene HMGA2 in lymphangiomyomatosis. Cancer Res. 2007 Mar 1;67(5):1902-9 |
2 | J:223798 Golden EJ, Benito-Gonzalez A, Doetzlhofer A, The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3864-73 |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
2* | J:319763 Negishi T, Mihara N, Chiba T, D'Armiento J, Chada K, Maeda M, Igarashi M, Imai K, High mobility group AT-hook 2 regulates osteoblast differentiation and facial bone development. Biochem Biophys Res Commun. 2022 Jan 29;590:68-74 |
1 | J:95925 Park YK, Franklin JL, Settle SH, Levy SE, Chung E, Jeyakumar LH, Shyr Y, Washington MK, Whitehead RH, Aronow BJ, Coffey RJ, Gene expression profile analysis of mouse colon embryonic development. Genesis. 2005 Jan;41(1):1-12 |
1* | J:74341 Schiltz JF, Kesari K, Ashar HR, Chada K, Hmgi-c-independent Activation of MuRantes in Vivo. Cell Growth Differ. 2002 Jan;13(1):39-45 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
1 | J:316134 Zhong X, Liu X, Li Y, Cheng M, Wang W, Tian K, Mu L, Zeng T, Liu Y, Jiang X, Yu L, Gao L, Zhou Y, HMGA2 sustains self-renewal and invasiveness of glioma-initiating cells. Oncotarget. 2016 Jul 12;7(28):44365-44380 |
1* | J:28571 Zhou X, Benson KF, Ashar HR, Chada K, Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C [see comments]. Nature. 1995 Aug 31;376(6543):771-4 |
Hmgb1 high mobility group box 1 (Synonyms: amphoterin, DEF, Hmg1, HMG-1, p30, SBP-1) | |
Results | Reference |
1 | J:299239 Qin X, Jiang Q, Nagano K, Moriishi T, Miyazaki T, Komori H, Ito K, Mark KV, Sakane C, Kaneko H, Komori T, Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts. PLoS Genet. 2020 Nov;16(11):e1009169 |
1 | J:125052 Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H, Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification. Mol Cell Biol. 2007 Aug;27(16):5650-63 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Hmgb2 high mobility group box 2 (Synonyms: Hmg2, HMG-2) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Hmgb3 high mobility group box 3 (Synonyms: Hmg2a, Hmg4) | |
Results | Reference |
2* | J:47656 Vaccari T, Beltrame M, Ferrari S, Bianchi ME, Hmg4, a new member of the Hmg1/2 gene family. Genomics. 1998 Apr 15;49(2):247-52 |
Hmgcr 3-hydroxy-3-methylglutaryl-Coenzyme A reductase (Synonyms: 3-hydroxy-3-methylglutaryl-CoA reductase, HMG-CoAR, Red) | |
Results | Reference |
1 | J:336898 Edwards W, Greco TM, Miner GE, Barker NK, Herring L, Cohen S, Cristea IM, Conlon FL, Quantitative proteomic profiling identifies global protein network dynamics in murine embryonic heart development. Dev Cell. 2023 Jun 19;58(12):1087-1105.e4 |
1* | J:190090 Hasegawa S, Kume H, Iinuma S, Yamasaki M, Takahashi N, Fukui T, Acetoacetyl-CoA synthetase is essential for normal neuronal development. Biochem Biophys Res Commun. 2012 Oct 19;427(2):398-403 |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
1 | J:264124 Tsushima H, Tang YJ, Puviindran V, Hsu SC, Nadesan P, Yu C, Zhang H, Mirando AJ, Hilton MJ, Alman BA, Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis. Development. 2018 Jul 9;145(13):dev162396 |
Hmgcs1 3-hydroxy-3-methylglutaryl-Coenzyme A synthase 1 (Synonyms: B130032C06Rik) | |
Results | Reference |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
1 | J:264124 Tsushima H, Tang YJ, Puviindran V, Hsu SC, Nadesan P, Yu C, Zhang H, Mirando AJ, Hilton MJ, Alman BA, Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis. Development. 2018 Jul 9;145(13):dev162396 |
Hmgn1 high mobility group nucleosomal binding domain 1 (Synonyms: Hmg14, HMG-14) | |
Results | Reference |
1* | J:294694 Furusawa T, Lim JH, Catez F, Birger Y, Mackem S, Bustin M, Down-regulation of nucleosomal binding protein HMGN1 expression during embryogenesis modulates Sox9 expression in chondrocytes. Mol Cell Biol. 2006 Jan;26(2):592-604 |
1* | J:137620 Lucey MM, Wang Y, Bustin M, Duncan MK, Differential expression of the HMGN family of chromatin proteins during ocular development. Gene Expr Patterns. 2008 Jul;8(6):433-7 |
Hmgn2 high mobility group nucleosomal binding domain 2 (Synonyms: Hmg17, HMG-17) | |
Results | Reference |
2 | J:327958 Eliason S, Su D, Pinho F, Sun Z, Zhang Z, Li X, Sweat M, Venugopalan SR, He B, Bustin M, Amendt BA, HMGN2 represses gene transcription via interaction with transcription factors Lef-1 and Pitx2 during amelogenesis. J Biol Chem. 2022 Jul 21;298(9):102295 |
2 | J:203117 Li X, Venugopalan SR, Cao H, Pinho FO, Paine ML, Snead ML, Semina EV, Amendt BA, A model for the molecular underpinnings of tooth defects in Axenfeld-Rieger syndrome. Hum Mol Genet. 2014 Jan 1;23(1):194-208 |
1* | J:137620 Lucey MM, Wang Y, Bustin M, Duncan MK, Differential expression of the HMGN family of chromatin proteins during ocular development. Gene Expr Patterns. 2008 Jul;8(6):433-7 |
Hmgn3 high mobility group nucleosomal binding domain 3 (Synonyms: 1110002A15Rik, 6330514M13Rik, HMGN3a, HMGN3b, TRIP7) | |
Results | Reference |
1* | J:137620 Lucey MM, Wang Y, Bustin M, Duncan MK, Differential expression of the HMGN family of chromatin proteins during ocular development. Gene Expr Patterns. 2008 Jul;8(6):433-7 |
Hmmr hyaluronan mediated motility receptor (RHAMM) (Synonyms: CD168, Rhamm) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
Hmox1 heme oxygenase 1 (Synonyms: D8Wsu38e, heme oxygenase 1, Hmox, HO-1, HO1, Hsp32) | |
Results | Reference |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
2* | J:341254 Rana M, Bajaj D, Choubey P, Jain S, Basu-Modak S, Altered Expression of Heme Oxygenase 2 in Heme Oxygenase 1-deficient Mouse Embryos. J Histochem Cytochem. 2023 Aug;71(8):431-450 |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
2 | J:222173 Solano ME, Kowal MK, O'Rourke GE, Horst AK, Modest K, Plosch T, Barikbin R, Remus CC, Berger RG, Jago C, Ho H, Sass G, Parker VJ, Lydon JP, DeMayo FJ, Hecher K, Karimi K, Arck PC, Progesterone and HMOX-1 promote fetal growth by CD8+ T cell modulation. J Clin Invest. 2015 Apr;125(4):1726-38 |
1* | J:293511 Suttorp CM, Cremers NA, van Rheden R, Regan RF, Helmich P, van Kempen S, Kuijpers-Jagtman AM, Wagener FADTG, Chemokine Signaling during Midline Epithelial Seam Disintegration Facilitates Palatal Fusion. Front Cell Dev Biol. 2017;5:94 |
1* | J:31372 Tanaka Y, Kobayashi K, Kita M, Kinoshita S, Imanishi J, Messenger RNA expression of heat shock proteins (HSPs) during ocular development. Curr Eye Res. 1995 Dec;14(12):1125-33 |
1 | J:308907 Verheijen N, Suttorp CM, van Rheden REM, Regan RF, Helmich MPAC, Kuijpers-Jagtman AM, Wagener FADTG, CXCL12-CXCR4 Interplay Facilitates Palatal Osteogenesis in Mice. Front Cell Dev Biol. 2020;8:771 |
1* | J:91332 Watanabe S, Akagi R, Mori M, Tsuchiya T, Sassa S, Marked developmental changes in heme oxygenase-1 (HO-1) expression in the mouse placenta: correlation between HO-1 expression and placental development. Placenta. 2004 May;25(5):387-95 |
Hmox2 heme oxygenase 2 (Synonyms: HO-2, HO2) | |
Results | Reference |
2* | J:341254 Rana M, Bajaj D, Choubey P, Jain S, Basu-Modak S, Altered Expression of Heme Oxygenase 2 in Heme Oxygenase 1-deficient Mouse Embryos. J Histochem Cytochem. 2023 Aug;71(8):431-450 |
1* | J:91332 Watanabe S, Akagi R, Mori M, Tsuchiya T, Sassa S, Marked developmental changes in heme oxygenase-1 (HO-1) expression in the mouse placenta: correlation between HO-1 expression and placental development. Placenta. 2004 May;25(5):387-95 |
Hmx1 H6 homeobox 1 (Synonyms: Nkx5-3) | |
Results | Reference |
1 | J:126770 Hodge LK, Klassen MP, Han BX, Yiu G, Hurrell J, Howell A, Rousseau G, Lemaigre F, Tessier-Lavigne M, Wang F, Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps. Neuron. 2007 Aug 16;55(4):572-86 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:357469 Sivori M, Dempsey B, Chettouh Z, Boismoreau F, Ayerdi M, et al., The pelvic organs receive no parasympathetic innervation. Elife. 2024;15 |
1 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
Hmx2 H6 homeobox 2 (Synonyms: Nkx5-2) | |
Results | Reference |
1 | J:237201 Espinosa-Medina I, Saha O, Boismoreau F, Chettouh Z, Rossi F, Richardson WD, Brunet JF, The sacral autonomic outflow is sympathetic. Science. 2016 Nov 18;354(6314):893-897 |
1 | J:347618 Qin T, So KKH, Hui CC, Sham MH, Ptch1 is essential for cochlear marginal cell differentiation and stria vascularis formation. Cell Rep. 2024 Apr 23;43(4):114083 |
1 | J:357469 Sivori M, Dempsey B, Chettouh Z, Boismoreau F, Ayerdi M, et al., The pelvic organs receive no parasympathetic innervation. Elife. 2024;15 |
1 | J:92940 Wang W, Grimmer JF, Van De Water TR, Lufkin T, Hmx2 and Hmx3 homeobox genes direct development of the murine inner ear and hypothalamus and can be functionally replaced by Drosophila Hmx. Dev Cell. 2004 Sep;7(3):439-53 |
Hmx3 H6 homeobox 3 (Synonyms: Nkx5-1, Nkx5.1) | |
Results | Reference |
1 | J:237201 Espinosa-Medina I, Saha O, Boismoreau F, Chettouh Z, Rossi F, Richardson WD, Brunet JF, The sacral autonomic outflow is sympathetic. Science. 2016 Nov 18;354(6314):893-897 |
1 | J:357469 Sivori M, Dempsey B, Chettouh Z, Boismoreau F, Ayerdi M, et al., The pelvic organs receive no parasympathetic innervation. Elife. 2024;15 |
1 | J:92940 Wang W, Grimmer JF, Van De Water TR, Lufkin T, Hmx2 and Hmx3 homeobox genes direct development of the murine inner ear and hypothalamus and can be functionally replaced by Drosophila Hmx. Dev Cell. 2004 Sep;7(3):439-53 |
Hnf1a HNF1 homeobox A (Synonyms: hepatocyte nuclear factor 1, Hnf-1, HNF1, HNF1[a], HNF1-alpha, Hnf1alpha, LFB1, Tcf1) | |
Results | Reference |
2 | J:122635 Bosse T, Fialkovich JJ, Piaseckyj CM, Beuling E, Broekman H, Grand RJ, Montgomery RK, Krasinski SD, Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development. Am J Physiol Gastrointest Liver Physiol. 2007 May;292(5):G1302-14 |
1 | J:111670 Kyrmizi I, Hatzis P, Katrakili N, Tronche F, Gonzalez FJ, Talianidis I, Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev. 2006 Aug 15;20(16):2293-305 |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1 | J:153980 Matsushita T, Chan YY, Kawanami A, Balmes G, Landreth GE, Murakami S, Extracellular signal-regulated kinase 1 (ERK1) and ERK2 play essential roles in osteoblast differentiation and in supporting osteoclastogenesis. Mol Cell Biol. 2009 Nov;29(21):5843-57 |
1 | J:79272 Nammo T, Yamagata K, Hamaoka R, Zhu Q, Akiyama TE, Gonzalez FJ, Miyagawa J, Matsuzawa Y, Expression profile of MODY3/HNF-1alpha protein in the developing mouse pancreas. Diabetologia. 2002 Aug;45(8):1142-53 |
1 | J:306107 Niborski LL, Paces-Fessy M, Ricci P, Bourgeois A, Magalhaes P, Kuzma-Kuzniarska M, Lesaulnier C, Reczko M, Declercq E, Zurbig P, Doucet A, Umbhauer M, Cereghini S, Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model. Dis Model Mech. 2021 May 1;14(5):dmm047498 |
Hnf1aos1 HNF1 homeobox A, opposite strand 1 (Synonyms: Gm13824, Haster, Mi-Lnc70) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Hnf1b HNF1 homeobox B (Synonyms: hepatocyte nuclear factor-1 beta, Hnf1beta, HNF-1Beta, LFB3, Tcf-2, Tcf2, vHNF1) | |
Results | Reference |
1 | J:219809 Afelik S, Pool B, Schmerr M, Penton C, Jensen J, Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development. Dev Biol. 2015 Mar 15;399(2):204-17 |
1* | J:58079 Barbacci E, Reber M, Ott MO, Breillat C, Huetz F, Cereghini S, Variant hepatocyte nuclear factor 1 is required for visceral endoderm specification. Development. 1999 Nov;126(21):4795-805 |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
1 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
2 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
1 | J:111670 Kyrmizi I, Hatzis P, Katrakili N, Tronche F, Gonzalez FJ, Talianidis I, Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev. 2006 Aug 15;20(16):2293-305 |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
1 | J:230332 Nakano Y, Negishi N, Gocho S, Mine T, Sakurai Y, Yazawa M, Abe K, Yagita H, Habu S, Kageyama R, Kawaguchi Y, Hozumi K, Disappearance of centroacinar cells in the Notch ligand-deficient pancreas. Genes Cells. 2015 Jun;20(6):500-11 |
2 | J:306107 Niborski LL, Paces-Fessy M, Ricci P, Bourgeois A, Magalhaes P, Kuzma-Kuzniarska M, Lesaulnier C, Reczko M, Declercq E, Zurbig P, Doucet A, Umbhauer M, Cereghini S, Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model. Dis Model Mech. 2021 May 1;14(5):dmm047498 |
1 | J:185279 Paces-Fessy M, Fabre M, Lesaulnier C, Cereghini S, Hnf1b and Pax2 cooperate to control different pathways in kidney and ureter morphogenesis. Hum Mol Genet. 2012 Jul 15;21(14):3143-55 |
1 | J:125042 Pierreux CE, Poll AV, Kemp CR, Clotman F, Maestro MA, Cordi S, Ferrer J, Leyns L, Rousseau GG, Lemaigre FP, The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. Gastroenterology. 2006 Feb;130(2):532-41 |
1 | J:156016 Solar M, Cardalda C, Houbracken I, Martin M, Maestro MA, De Medts N, Xu X, Grau V, Heimberg H, Bouwens L, Ferrer J, Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth. Dev Cell. 2009 Dec;17(6):849-60 |
1 | J:174261 Tchorz JS, Kinter J, Muller M, Tornillo L, Heim MH, Bettler B, Notch2 signaling promotes biliary epithelial cell fate specification and tubulogenesis during bile duct development in mice. Hepatology. 2009 Sep;50(3):871-9 |
2 | J:231427 Vanderpool C, Sparks EE, Huppert KA, Gannon M, Means AL, Huppert SS, Genetic interactions between hepatocyte nuclear factor-6 and Notch signaling regulate mouse intrahepatic bile duct development in vivo. Hepatology. 2012 Jan;55(1):233-43 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Hnf4a hepatic nuclear factor 4, alpha (Synonyms: Hnf4, HNF-4, HNF4 alpha, MODY1, Nr2a1, Nuclear receptor 2A1, Tcf14, Tcf4) | |
Results | Reference |
1 | J:111407 Beaudry JB, Pierreux CE, Hayhurst GP, Plumb-Rudewiez N, Weiss MC, Rousseau GG, Lemaigre FP, Threshold levels of hepatocyte nuclear factor 6 (HNF-6) acting in synergy with HNF-4 and PGC-1alpha are required for time-specific gene expression during liver development. Mol Cell Biol. 2006 Aug;26(16):6037-46 |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1* | J:284137 Chen L, Toke NH, Luo S, Vasoya RP, Aita R, Parthasarathy A, Tsai YH, Spence JR, Verzi MP, HNF4 factors control chromatin accessibility and are redundantly required for maturation of the fetal intestine. Development. 2019 Aug 6;146(19):dev179432 |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1 | J:168727 Furuyama K, Kawaguchi Y, Akiyama H, Horiguchi M, Kodama S, Kuhara T, Hosokawa S, Elbahrawy A, Soeda T, Koizumi M, Masui T, Kawaguchi M, Takaori K, Doi R, Nishi E, Kakinoki R, Deng JM, Behringer RR, Nakamura T, Uemoto S, Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet. 2011 Jan;43(1):34-41 |
2 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1* | J:124126 Hunter MP, Wilson CM, Jiang X, Cong R, Vasavada H, Kaestner KH, Bogue CW, The homeobox gene Hhex is essential for proper hepatoblast differentiation and bile duct morphogenesis. Dev Biol. 2007 Aug 15;308(2):355-67 |
2 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
1 | J:111670 Kyrmizi I, Hatzis P, Katrakili N, Tronche F, Gonzalez FJ, Talianidis I, Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev. 2006 Aug 15;20(16):2293-305 |
1 | J:240786 Lee DH, Park JO, Kim TS, Kim SK, Kim TH, Kim MC, Park GS, Kim JH, Kuninaka S, Olson EN, Saya H, Kim SY, Lee H, Lim DS, LATS-YAP/TAZ controls lineage specification by regulating TGFbeta signaling and Hnf4alpha expression during liver development. Nat Commun. 2016 Jun 30;7:11961 |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1* | J:140018 Luebke-Wheeler J, Zhang K, Battle M, Si-Tayeb K, Garrison W, Chhinder S, Li J, Kaufman RJ, Duncan SA, Hepatocyte nuclear factor 4alpha is implicated in endoplasmic reticulum stress-induced acute phase response by regulating expression of cyclic adenosine monophosphate responsive element binding protein H. Hepatology. 2008 Oct;48(4):1242-50 |
1 | J:320686 Molina LM, Zhu J, Li Q, Pradhan-Sundd T, Krutsenko Y, Sayed K, Jenkins N, Vats R, Bhushan B, Ko S, Hu S, Poddar M, Singh S, Tao J, Sundd P, Singhi A, Watkins S, Ma X, Benos PV, Feranchak A, Michalopoulos G, Nejak-Bowen K, Watson A, Bell A, Monga SP, Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors. Cell Rep. 2021 Jul 6;36(1):109310 |
1* | J:130176 Nammo T, Yamagata K, Tanaka T, Kodama T, Sladek FM, Fukui K, Katsube F, Sato Y, Miyagawa J, Shimomura I, Expression of HNF-4alpha (MODY1), HNF-1beta (MODY5), and HNF-1alpha (MODY3) proteins in the developing mouse pancreas. Gene Expr Patterns. 2008 Jan;8(2):96-106 |
1 | J:306107 Niborski LL, Paces-Fessy M, Ricci P, Bourgeois A, Magalhaes P, Kuzma-Kuzniarska M, Lesaulnier C, Reczko M, Declercq E, Zurbig P, Doucet A, Umbhauer M, Cereghini S, Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model. Dis Model Mech. 2021 May 1;14(5):dmm047498 |
1 | J:151981 Spence JR, Lange AW, Lin SC, Kaestner KH, Lowy AM, Kim I, Whitsett JA, Wells JM, Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell. 2009 Jul;17(1):62-74 |
1* | J:267238 Sun K, Battle MA, Misra RP, Duncan SA, Hepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice. Hepatology. 2009 May;49(5):1645-54 |
1 | J:134487 Suzuki A, Sekiya S, Buscher D, Izpisua Belmonte JC, Taniguchi H, Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression. Development. 2008 May;135(9):1589-95 |
1* | J:21238 Taraviras S, Monaghan AP, Schutz G, Kelsey G, Characterization of the mouse HNF-4 gene and its expression during mouse embryogenesis. Mech Dev. 1994 Nov;48(2):67-79 |
1 | J:174261 Tchorz JS, Kinter J, Muller M, Tornillo L, Heim MH, Bettler B, Notch2 signaling promotes biliary epithelial cell fate specification and tubulogenesis during bile duct development in mice. Hepatology. 2009 Sep;50(3):871-9 |
2* | J:73291 Torres-Padilla ME, Fougere-Deschatrette C, Weiss MC, Expression of HNF4alpha isoforms in mouse liver development is regulated by sequential promoter usage and constitutive 3' end splicing. Mech Dev. 2001 Dec;109(2):183-93 |
1 | J:352714 Yang J, Zhang YN, Wang RX, Hao CZ, Qiu Y, Chi H, Luan WS, Tang H, Zhang XJ, Sun X, Sheps JA, Ling V, Cao M, Wang JS, ZFYVE19 deficiency: a ciliopathy involving failure of cell division, with cell death. J Med Genet. 2024 Jul 19;61(8):750-758 |
1* | J:272566 Yang R, Wang H, Kang B, Chen B, Shi Y, Yang S, Sun L, Liu Y, Xiao W, Zhang T, Yang J, Zhang Y, Zhu M, Xu P, Chang Y, Jia Y, Huang Y, CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Hnf4aos hepatic nuclear factor 4 alpha, opposite strand (Synonyms: 0610008F07Rik) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Hnf4g hepatocyte nuclear factor 4, gamma (Synonyms: NR2A2) | |
Results | Reference |
1* | J:284137 Chen L, Toke NH, Luo S, Vasoya RP, Aita R, Parthasarathy A, Tsai YH, Spence JR, Verzi MP, HNF4 factors control chromatin accessibility and are redundantly required for maturation of the fetal intestine. Development. 2019 Aug 6;146(19):dev179432 |
1* | J:154372 Li X, Udager AM, Hu C, Qiao XT, Richards N, Gumucio DL, Dynamic patterning at the pylorus: Formation of an epithelial intestine-stomach boundary in late fetal life. Dev Dyn. 2009 Oct 29;238(12):3205-3217 |
Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 (Synonyms: D15Ertd119e, Hdp, hnrnp-A, Hnrpa1) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Hnrnpab heterogeneous nuclear ribonucleoprotein A/B (Synonyms: CBF-A, Cgbfa, Hnrpab) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Hnrnpd heterogeneous nuclear ribonucleoprotein D (Synonyms: Auf1, Hnrpd) | |
Results | Reference |
1* | J:117588 Banihashemi L, Wilson GM, Das N, Brewer G, Upf1/Upf2 regulation of 3' untranslated region splice variants of AUF1 links nonsense-mediated and A+U-rich element-mediated mRNA decay. Mol Cell Biol. 2006 Dec;26(23):8743-54 |
2* | J:66029 Gouble A, Morello D, Synchronous and regulated expression of two AU-binding proteins, AUF1 and HuR, throughout murine development. Oncogene. 2000 Nov 9;19(47):5377-84 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Hnrnpdl heterogeneous nuclear ribonucleoprotein D-like (Synonyms: D5Ertd650e, D5Wsu145e, hnRNP-DL, Hnrpdl, JKTBP) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Hnrnph1 heterogeneous nuclear ribonucleoprotein H1 (Synonyms: E430005G16Rik, Hnrph1) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
2 | J:338313 Korff A, Yang X, O'Donovan K, Gonzalez A, Teubner BJ, Nakamura H, Messing J, Yang F, Carisey AF, Wang YD, Patni T, Sheppard H, Zakharenko SS, Chook YM, Taylor JP, Kim HJ, A murine model of hnRNPH2-related neurodevelopmental disorder reveals a mechanism for genetic compensation by Hnrnph1. J Clin Invest. 2023 Jul 17;133(14) |
1 | J:340389 Luo Z, Xia M, Shi W, Zhao C, Wang J, Xin D, Dong X, Xiong Y, Zhang F, Berry K, Ogurek S, Liu X, Rao R, Xing R, Wu LMN, Cui S, Xu L, Lin Y, Ma W, Tian S, Xie Q, Zhang L, Xin M, Wang X, Yue F, Zheng H, Liu Y, Stevenson CB, de Blank P, Perentesis JP, Gilbertson RJ, Li H, Ma J, Zhou W, Taylor MD, Lu QR, Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis. Nature. 2022 Dec;612(7941):787-794 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Hnrnph2 heterogeneous nuclear ribonucleoprotein H2 (Synonyms: Ftp3, Hnrph2) | |
Results | Reference |
2 | J:338313 Korff A, Yang X, O'Donovan K, Gonzalez A, Teubner BJ, Nakamura H, Messing J, Yang F, Carisey AF, Wang YD, Patni T, Sheppard H, Zakharenko SS, Chook YM, Taylor JP, Kim HJ, A murine model of hnRNPH2-related neurodevelopmental disorder reveals a mechanism for genetic compensation by Hnrnph1. J Clin Invest. 2023 Jul 17;133(14) |
Hnrnph3 heterogeneous nuclear ribonucleoprotein H3 (Synonyms: hnRNP 2H9, Hnrph3) | |
Results | Reference |
1 | J:63624 Mahe D, Fischer N, Decimo D, Fuchs J, Spatiotemporal regulation of hnRNP M and 2H9 gene expression during mouse embryonic development. Biochim Biophys Acta. 2000 Jul 24;1492(2-3):414-24 |
Hnrnpk heterogeneous nuclear ribonucleoprotein K (Synonyms: hnRNPK, Hnrpk, KBBP) | |
Results | Reference |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Hnrnpm heterogeneous nuclear ribonucleoprotein M (Synonyms: 2610023M21Rik, Hnrpm) | |
Results | Reference |
1 | J:63624 Mahe D, Fischer N, Decimo D, Fuchs J, Spatiotemporal regulation of hnRNP M and 2H9 gene expression during mouse embryonic development. Biochim Biophys Acta. 2000 Jul 24;1492(2-3):414-24 |
Hnrnpr heterogeneous nuclear ribonucleoprotein R (Synonyms: 2610003J05Rik, 2610528B01Rik, hnRNPR, Hnrpr) | |
Results | Reference |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Hopx HOP homeobox (Synonyms: 1110018K11Rik, 1200015P04Rik, 2300002F06Rik, Cameo, Hod, Hop, Ob1, Toto) | |
Results | Reference |
1* | J:79153 Chen F, Kook H, Milewski R, Gitler A, Lu M, Li J, Nazarian R, Schnepp R, Jen K, Biben C, Runke G, Mackay J, Novotny J, Schwartz R, Harvey R, Mullins M, Epstein J, Hop Is an Unusual Homeobox Gene that Modulates Cardiac Development. Cell. 2002 Sep 20;110(6):713 |
1* | J:291486 Daniel E, Barlow HR, Sutton GI, Gu X, Htike Y, Cowdin MA, Cleaver O, Cyp26b1 is an essential regulator of distal airway epithelial differentiation during lung development. Development. 2020 Feb 20;147(4):dev181560 |
1 | J:316977 Endale M, Ahlfeld S, Bao E, Chen X, Green J, Bess Z, Weirauch MT, Xu Y, Perl AK, Temporal, spatial, and phenotypical changes of PDGFRalpha expressing fibroblasts during late lung development. Dev Biol. 2017 May 15;425(2):161-175 |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1* | J:348284 Hassan D, Chen J, CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair. Nat Commun. 2024 May 16;15(1):4148 |
1 | J:259186 Heng X, Guo Q, Leung AW, Li JY, Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6:e23253 |
1 | J:245319 Jain R, Li D, Gupta M, Manderfield LJ, Ifkovits JL, Wang Q, Liu F, Liu Y, Poleshko A, Padmanabhan A, Raum JC, Li L, Morrisey EE, Lu MM, Won KJ, Epstein JA, HEART DEVELOPMENT. Integration of Bmp and Wnt signaling by Hopx specifies commitment of cardiomyoblasts. Science. 2015 Jun 26;348(6242):aaa6071 |
1* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
2 | J:237343 Laresgoiti U, Nikolic MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL, Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016 Oct 15;143(20):3686-3699 |
1 | J:315454 Loscertales M, Nicolaou F, Jeanne M, Longoni M, Gould DB, Sun Y, Maalouf FI, Nagy N, Donahoe PK, Type IV collagen drives alveolar epithelial-endothelial association and the morphogenetic movements of septation. BMC Biol. 2016 Jul 13;14:59 |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
1* | J:99638 Muhlfriedel S, Kirsch F, Gruss P, Stoykova A, Chowdhury K, A roof plate-dependent enhancer controls the expression of Homeodomain only protein in the developing cerebral cortex. Dev Biol. 2005 Jul 15;283(2):522-34 |
1* | J:79152 Shin CH, Liu ZP, Passier R, Zhang CL, Wang DZ, Harris TM, Yamagishi H, Richardson JA, Childs G, Olson EN, Modulation of cardiac growth and development by HOP, an unusual homeodomain protein. Cell. 2002 Sep 20;110(6):725-35 |
2 | J:121421 Shu W, Lu MM, Zhang Y, Tucker PW, Zhou D, Morrisey EE, Foxp2 and Foxp1 cooperatively regulate lung and esophagus development. Development. 2007 May;134(10):1991-2000 |
1 | J:354182 Sun M, Gao Y, Li Z, Yang L, Liu G, Xu Z, Guo R, You Y, Yang Z, ERK signaling expands mammalian cortical radial glial cells and extends the neurogenic period. Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2314802121 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
1 | J:293532 Vaid S, Camp JG, Hersemann L, Eugster Oegema C, Heninger AK, Winkler S, Brandl H, Sarov M, Treutlein B, Huttner WB, Namba T, A novel population of Hopx-dependent basal radial glial cells in the developing mouse neocortex. Development. 2018 Oct 18;145(20):dev169276 |
1 | J:353791 Xu L, Tan C, Barr J, Talaba N, Verheyden J, Chin JS, Gaboyan S, Kasaraneni N, Elgamal RM, Gaulton KJ, Lin G, Afshar K, Golts E, Meier A, Alexander LEC, Borok Z, Shen Y, Chung WK, McCulley DJ, Sun X, Context-dependent roles of mitochondrial LONP1 in orchestrating the balance between airway progenitor versus progeny cells. Cell Stem Cell. 2024 Aug 16; |
Hormad1 HORMA domain containing 1 (Synonyms: 4921522K05Rik, Nohma) | |
Results | Reference |
1 | J:325094 Guan Y, Lin H, Leu NA, Ruthel G, Fuchs SY, Busino L, Luo M, Wang PJ, SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination. Nucleic Acids Res. 2022 May 20;50(9):5129-5144 |
Hotair HOX transcript antisense RNA (non-protein coding) | |
Results | Reference |
1 | J:275070 Lu X, Bai D, Liu X, Zhou C, Yang G, Sedentary lifestyle related exosomal release of Hotair from gluteal-femoral fat promotes intestinal cell proliferation. Sci Rep. 2017 Mar 31;7:45648 |
Hottip Hoxa distal transcript antisense RNA (Synonyms: ENSMUSG00000055408, Gm15053) | |
Results | Reference |
1* | J:289776 Mao G, Kang Y, Lin R, Hu S, Zhang Z, Li H, Liao W, Zhang Z, Long Non-coding RNA HOTTIP Promotes CCL3 Expression and Induces Cartilage Degradation by Sponging miR-455-3p. Front Cell Dev Biol. 2019;7:161 |
Hoxa1 homeobox A1 (Synonyms: early retinoic acid, ERA1, Hox-1.6) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:44152 Mollard R, Dziadek M, Homeobox genes from clusters A and B demonstrate characteristics of temporal colinearity and differential restrictions in spatial expression domains in the branching mouse lung. Int J Dev Biol. 1997 Oct;41(5):655-66 |
Hoxa2 homeobox A2 (Synonyms: Hox-1.11) | |
Results | Reference |
1 | J:193244 Di Meglio T, Kratochwil CF, Vilain N, Loche A, Vitobello A, Yonehara K, Hrycaj SM, Roska B, Peters AH, Eichmann A, Wellik D, Ducret S, Rijli FM, Ezh2 orchestrates topographic migration and connectivity of mouse precerebellar neurons. Science. 2013 Jan 11;339(6116):204-7 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
2 | J:57955 Hao Z, Yeung J, Wolf L, Doucette R, Nazarali A, Differential expression of Hoxa-2 protein along the dorsal-ventral axis of the developing and adult mouse spinal cord. Dev Dyn. 1999 Oct;216(2):201-17 |
1* | J:221341 Lun MP, Johnson MB, Broadbelt KG, Watanabe M, Kang YJ, Chau KF, Springel MW, Malesz A, Sousa AM, Pletikos M, Adelita T, Calicchio ML, Zhang Y, Holtzman MJ, Lidov HG, Sestan N, Steen H, Monuki ES, Lehtinen MK, Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production. J Neurosci. 2015 Mar 25;35(12):4903-16 |
1 | J:124957 Pasqualetti M, Diaz C, Renaud JS, Rijli FM, Glover JC, Fate-mapping the mammalian hindbrain: segmental origins of vestibular projection neurons assessed using rhombomere-specific Hoxa2 enhancer elements in the mouse embryo. J Neurosci. 2007 Sep 5;27(36):9670-81 |
1 | J:296045 Patmore DM, Jassim A, Nathan E, Gilbertson RJ, Tahan D, Hoffmann N, Tong Y, Smith KS, Kanneganti TD, Suzuki H, Taylor MD, Northcott P, Gilbertson RJ, DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma. Dev Cell. 2020 Aug 24;54(4):455-470.e5 |
1* | J:74097 Wolf LV, Yeung JM, Doucette JR, Nazarali AJ, Coordinated expression of Hoxa2, Hoxd1 and Pax6 in the developing diencephalon. Neuroreport. 2001 Feb 12;12(2):329-33 |
Hoxa3 homeobox A3 (Synonyms: Hox-1.5, Mo-10) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1* | J:71183 Su D, Ellis S, Napier A, Lee K, Manley NR, Hoxa3 and pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis. Dev Biol. 2001 Aug 15;236(2):316-29 |
Hoxa4 homeobox A4 (Synonyms: Hox-1.4) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:44152 Mollard R, Dziadek M, Homeobox genes from clusters A and B demonstrate characteristics of temporal colinearity and differential restrictions in spatial expression domains in the branching mouse lung. Int J Dev Biol. 1997 Oct;41(5):655-66 |
1* | J:66282 Packer AI, Jane-wit D, McLean L, Panteleyev AA, Christiano AM, Wolgemuth DJ, Hoxa4 expression in developing mouse hair follicles and skin. Mech Dev. 2000 Dec;99(1-2):153-7 |
2 | J:60124 Pitera JE, Smith VV, Thorogood P, Milla PJ, Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code. Gastroenterology. 1999 Dec;117(6):1339-51 |
1 | J:8339 Rubin MR, Toth LE, Patel MD, D'Eustachio P, Nguyen-Huu MC, A mouse homeo box gene is expressed in spermatocytes and embryos. Science. 1986 Aug 8;233(4764):663-7 |
1* | J:8812 Wolgemuth DJ, Viviano CM, Gizang-Ginsberg E, Frohman MA, Joyner AL, Martin GR, Differential expression of the mouse homeobox-containing gene Hox-1.4 during male germ cell differentiation and embryonic development. Proc Natl Acad Sci U S A. 1987 Aug;84(16):5813-7 |
Hoxa5 homeobox A5 (Synonyms: Hox-1.3) | |
Results | Reference |
1 | J:193244 Di Meglio T, Kratochwil CF, Vilain N, Loche A, Vitobello A, Yonehara K, Hrycaj SM, Roska B, Peters AH, Eichmann A, Wellik D, Ducret S, Rijli FM, Ezh2 orchestrates topographic migration and connectivity of mouse precerebellar neurons. Science. 2013 Jan 11;339(6116):204-7 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:267950 Holzman MA, Bergmann JM, Feldman M, Landry-Truchon K, Jeannotte L, Mansfield JH, HOXA5 protein expression and genetic fate mapping show lineage restriction in the developing musculoskeletal system. Int J Dev Biol. 2018;62(11-12):785-796 |
1* | J:314181 Holzman MA, Ryckman A, Finkelstein TM, Landry-Truchon K, Schindler KA, Bergmann JM, Jeannotte L, Mansfield JH, HOXA5 Participates in Brown Adipose Tissue and Epaxial Skeletal Muscle Patterning and in Brown Adipocyte Differentiation. Front Cell Dev Biol. 2021;9:632303 |
2* | J:65659 Kim C, Nielsen HC, Hoxa-5 in mouse developing lung: cell-specific expression and retinoic acid regulation. Am J Physiol Lung Cell Mol Physiol. 2000 Nov;279(5):L863-71 |
1 | J:92171 Krieger KE, Abbott MA, Joksimovic M, Lueth PA, Sonea IM, Jeannotte L, Tuggle CK, Transgenic mice ectopically expressing HOXA5 in the dorsal spinal cord show structural defects of the cervical spinal cord along with sensory and motor defects of the forelimb. Brain Res Dev Brain Res. 2004 Jun 21;150(2):125-39 |
1 | J:245768 Landry-Truchon K, Houde N, Boucherat O, Joncas FH, Dasen JS, Philippidou P, Mansfield JH, Jeannotte L, HOXA5 plays tissue-specific roles in the developing respiratory system. Development. 2017 Oct 01;144(19):3547-3561 |
1 | J:335070 Li MH, Kuetemeyer JM, Yallowitz AR, Wellik DM, Characterization of a novel Hoxa5eGFP mouse line. Dev Dyn. 2023 Apr;252(4):536-546 |
1 | J:241156 Lizen B, Hutlet B, Bissen D, Sauvegarde D, Hermant M, Ahn MT, Gofflot F, HOXA5 localization in postnatal and adult mouse brain is suggestive of regulatory roles in postmitotic neurons. J Comp Neurol. 2017 Apr 01;525(5):1155-1175 |
1 | J:306314 Maheshwari U, Kraus D, Vilain N, Holwerda SJB, Cankovic V, Maiorano NA, Kohler H, Satoh D, Sigrist M, Arber S, Kratochwil CF, Di Meglio T, Ducret S, Rijli FM, Postmitotic Hoxa5 Expression Specifies Pontine Neuron Positional Identity and Input Connectivity of Cortical Afferent Subsets. Cell Rep. 2020 Jun 16;31(11):107767 |
1 | J:8923 Odenwald WF, Taylor CF, Palmer-Hill FJ, Friedrich V Jr, Tani M, Lazzarini RA, Expression of a homeo domain protein in noncontact-inhibited cultured cells and postmitotic neurons. Genes Dev. 1987 Jul;1(5):482-96 |
2 | J:60124 Pitera JE, Smith VV, Thorogood P, Milla PJ, Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code. Gastroenterology. 1999 Dec;117(6):1339-51 |
2 | J:139520 Volpe MV, Wang KT, Nielsen HC, Chinoy MR, Unique spatial and cellular expression patterns of Hoxa5, Hoxb4, and Hoxb6 proteins in normal developing murine lung are modified in pulmonary hypoplasia. Birth Defects Res A Clin Mol Teratol. 2008 Aug;82(8):571-84 |
Hoxa6 homeobox A6 (Synonyms: Hox-1.2) | |
Results | Reference |
1 | J:8127 Colberg-Poley AM, Voss SD, Chowdhury K, Stewart CL, Wagner EF, Gruss P, Clustered homeo boxes are differentially expressed during murine development. Cell. 1985 Nov;43(1):39-45 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:239872 Larsen BM, Hrycaj SM, Newman M, Li Y, Wellik DM, Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation. Development. 2015 Nov 15;142(22):3859-68 |
1 | J:231980 Tomas-Roca L, Corral-San-Miguel R, Aroca P, Puelles L, Marin F, Crypto-rhombomeres of the mouse medulla oblongata, defined by molecular and morphological features. Brain Struct Funct. 2016 Mar;221(2):815-38 |
Hoxa7 homeobox A7 (Synonyms: Hox-1.1) | |
Results | Reference |
1 | J:8127 Colberg-Poley AM, Voss SD, Chowdhury K, Stewart CL, Wagner EF, Gruss P, Clustered homeo boxes are differentially expressed during murine development. Cell. 1985 Nov;43(1):39-45 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:44152 Mollard R, Dziadek M, Homeobox genes from clusters A and B demonstrate characteristics of temporal colinearity and differential restrictions in spatial expression domains in the branching mouse lung. Int J Dev Biol. 1997 Oct;41(5):655-66 |
Hoxa9 homeobox A9 (Synonyms: D6a9, Hox-1.7) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:242579 Malek R, Gajula RP, Williams RD, Nghiem B, Simons BW, Nugent K, Wang H, Taparra K, Lemtiri-Chlieh G, Yoon AR, True L, An SS, DeWeese TL, Ross AE, Schaeffer EM, Pienta KJ, Hurley PJ, Morrissey C, Tran PT, TWIST1-WDR5-Hottip Regulates Hoxa9 Chromatin to Facilitate Prostate Cancer Metastasis. Cancer Res. 2017 Jun 15;77(12):3181-3193 |
1* | J:8939 Rubin MR, King W, Toth LE, Sawczuk IS, Levine MS, D'Eustachio P, Nguyen-Huu MC, Murine Hox-1.7 homeo-box gene: cloning, chromosomal location, and expression [published erratum appears in Mol Cell Biol 1988 Dec;8(12):5593]. Mol Cell Biol. 1987 Oct;7(10):3836-41 |
Hoxa10 homeobox A10 (Synonyms: Hox-1.8, Hoxa-10) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:135432 Nightingale SS, Western P, Hutson JM, The migrating gubernaculum grows like a 'limb bud'. J Pediatr Surg. 2008 Feb;43(2):387-90 |
1 | J:51967 Podlasek CA, Seo RM, Clemens JQ, Ma L, Maas RL, Bushman W, Hoxa-10 deficient male mice exhibit abnormal development of the accessory sex organs. Dev Dyn. 1999 Jan;214(1):1-12 |
Hoxa11 homeobox A11 (Synonyms: Hox-1.9, Hoxa-11) | |
Results | Reference |
1 | J:90403 Boulet AM, Capecchi MR, Multiple roles of Hoxa11 and Hoxd11 in the formation of the mammalian forelimb zeugopod. Development. 2004 Jan;131(2):299-309 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:140709 Nelson LT, Rakshit S, Sun H, Wellik DM, Generation and expression of a Hoxa11eGFP targeted allele in mice. Dev Dyn. 2008 Nov;237(11):3410-6 |
1* | J:89197 Patterson LT, Potter SS, Atlas of Hox gene expression in the developing kidney. Dev Dyn. 2004 Apr;229(4):771-9 |
Hoxa13 homeobox A13 (Synonyms: Hox-1.10) | |
Results | Reference |
2* | J:75699 Albrecht AN, Schwabe GC, Stricker S, Boddrich A, Wanker EE, Mundlos S, The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67 |
1 | J:307093 Amato CM, Yao HH, Developmental and sexual dimorphic atlas of the prenatal mouse external genitalia at the single-cell level. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2103856118 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:131546 Rinn JL, Wang JK, Allen N, Brugmann SA, Mikels AJ, Liu H, Ridky TW, Stadler HS, Nusse R, Helms JA, Chang HY, A dermal HOX transcriptional program regulates site-specific epidermal fate. Genes Dev. 2008 Feb 1;22(3):303-7 |
Hoxb homeobox B cluster (Synonyms: Hox-2) | |
Results | Reference |
1 | J:8076 Jackson IJ, Schofield P, Hogan B, A mouse homoeo box gene is expressed during embryogenesis and in adult kidney. Nature. 1985 Oct 24-30;317(6039):745-8 |
Hoxb1 homeobox B1 (Synonyms: Hox-2.9) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:92081 Ma X, Kawamoto S, Hara Y, Adelstein RS, A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons. Mol Biol Cell. 2004 Jun;15(6):2568-79 |
1* | J:10556 Rubock MJ, Larin Z, Cook M, Papalopulu N, Krumlauf R, Lehrach H, A yeast artificial chromosome containing the mouse homeobox cluster Hox-2 [published erratum appears in Proc Natl Acad Sci U S A 1990 Sep;87(18):7346]. Proc Natl Acad Sci U S A. 1990 Jun;87(12):4751-5 |
Hoxb2 homeobox B2 (Synonyms: Hox-2.8, Hoxbes2) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:10556 Rubock MJ, Larin Z, Cook M, Papalopulu N, Krumlauf R, Lehrach H, A yeast artificial chromosome containing the mouse homeobox cluster Hox-2 [published erratum appears in Proc Natl Acad Sci U S A 1990 Sep;87(18):7346]. Proc Natl Acad Sci U S A. 1990 Jun;87(12):4751-5 |
Hoxb3 homeobox B3 (Synonyms: Hox-2.7) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1* | J:44152 Mollard R, Dziadek M, Homeobox genes from clusters A and B demonstrate characteristics of temporal colinearity and differential restrictions in spatial expression domains in the branching mouse lung. Int J Dev Biol. 1997 Oct;41(5):655-66 |
Hoxb3os homeobox B3 and homeobox B2, opposite strand (Synonyms: Gm11530) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Hoxb4 homeobox B4 (Synonyms: Hox-2.6) | |
Results | Reference |
1* | J:32282 Graham A, Papalopulu N, Lorimer J, McVey JH, Tuddenham EG, Krumlauf R, Characterization of a murine homeo box gene, Hox-2.6, related to the Drosophila Deformed gene. Genes Dev. 1988 Nov;2(11):1424-38 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:44152 Mollard R, Dziadek M, Homeobox genes from clusters A and B demonstrate characteristics of temporal colinearity and differential restrictions in spatial expression domains in the branching mouse lung. Int J Dev Biol. 1997 Oct;41(5):655-66 |
2 | J:60124 Pitera JE, Smith VV, Thorogood P, Milla PJ, Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code. Gastroenterology. 1999 Dec;117(6):1339-51 |
1 | J:231980 Tomas-Roca L, Corral-San-Miguel R, Aroca P, Puelles L, Marin F, Crypto-rhombomeres of the mouse medulla oblongata, defined by molecular and morphological features. Brain Struct Funct. 2016 Mar;221(2):815-38 |
2 | J:139520 Volpe MV, Wang KT, Nielsen HC, Chinoy MR, Unique spatial and cellular expression patterns of Hoxa5, Hoxb4, and Hoxb6 proteins in normal developing murine lung are modified in pulmonary hypoplasia. Birth Defects Res A Clin Mol Teratol. 2008 Aug;82(8):571-84 |
Hoxb5 homeobox B5 (Synonyms: Hox-2.1) | |
Results | Reference |
1* | J:32282 Graham A, Papalopulu N, Lorimer J, McVey JH, Tuddenham EG, Krumlauf R, Characterization of a murine homeo box gene, Hox-2.6, related to the Drosophila Deformed gene. Genes Dev. 1988 Nov;2(11):1424-38 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:32355 Hauser CA, Joyner AL, Klein RD, Learned TK, Martin GR, Tjian R, Expression of homologous homeo-box-containing genes in differentiated human teratocarcinoma cells and mouse embryos. Cell. 1985 Nov;43(1):19-28 |
1 | J:8076 Jackson IJ, Schofield P, Hogan B, A mouse homoeo box gene is expressed during embryogenesis and in adult kidney. Nature. 1985 Oct 24-30;317(6039):745-8 |
1 | J:8869 Krumlauf R, Holland PW, McVey JH, Hogan BL, Developmental and spatial patterns of expression of the mouse homeobox gene, Hox 2.1. Development. 1987 Apr;99(4):603-17 |
1 | J:306314 Maheshwari U, Kraus D, Vilain N, Holwerda SJB, Cankovic V, Maiorano NA, Kohler H, Satoh D, Sigrist M, Arber S, Kratochwil CF, Di Meglio T, Ducret S, Rijli FM, Postmitotic Hoxa5 Expression Specifies Pontine Neuron Positional Identity and Input Connectivity of Cortical Afferent Subsets. Cell Rep. 2020 Jun 16;31(11):107767 |
1 | J:60124 Pitera JE, Smith VV, Thorogood P, Milla PJ, Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code. Gastroenterology. 1999 Dec;117(6):1339-51 |
1* | J:112963 Sachan M, Raman R, Developmental methylation of the regulatory region of HoxB5 gene in mouse correlates with its tissue-specific expression. Gene. 2006 Oct 1;380(2):151-8 |
2* | J:45249 Volpe MV, Martin A, Vosatka RJ, Mazzoni CL, Nielsen HC, Hoxb-5 expression in the developing mouse lung suggests a role in branching morphogenesis and epithelial cell fate. Histochem Cell Biol. 1997 Dec;108(6):495-504 |
1* | J:39822 Zimmermann F, Rich IN, Mammalian homeobox B6 expression can be correlated with erythropoietin production sites and erythropoiesis during development, but not with hematopoietic or nonhematopoietic stem cell populations. Blood. 1997 Apr 15;89(8):2723-35 |
Hoxb6 homeobox B6 (Synonyms: Hox-2.2) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:239872 Larsen BM, Hrycaj SM, Newman M, Li Y, Wellik DM, Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation. Development. 2015 Nov 15;142(22):3859-68 |
1* | J:44152 Mollard R, Dziadek M, Homeobox genes from clusters A and B demonstrate characteristics of temporal colinearity and differential restrictions in spatial expression domains in the branching mouse lung. Int J Dev Biol. 1997 Oct;41(5):655-66 |
1 | J:231980 Tomas-Roca L, Corral-San-Miguel R, Aroca P, Puelles L, Marin F, Crypto-rhombomeres of the mouse medulla oblongata, defined by molecular and morphological features. Brain Struct Funct. 2016 Mar;221(2):815-38 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
2 | J:139520 Volpe MV, Wang KT, Nielsen HC, Chinoy MR, Unique spatial and cellular expression patterns of Hoxa5, Hoxb4, and Hoxb6 proteins in normal developing murine lung are modified in pulmonary hypoplasia. Birth Defects Res A Clin Mol Teratol. 2008 Aug;82(8):571-84 |
1* | J:39822 Zimmermann F, Rich IN, Mammalian homeobox B6 expression can be correlated with erythropoietin production sites and erythropoiesis during development, but not with hematopoietic or nonhematopoietic stem cell populations. Blood. 1997 Apr 15;89(8):2723-35 |
Hoxb7 homeobox B7 (Synonyms: Hox-2.3) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:44152 Mollard R, Dziadek M, Homeobox genes from clusters A and B demonstrate characteristics of temporal colinearity and differential restrictions in spatial expression domains in the branching mouse lung. Int J Dev Biol. 1997 Oct;41(5):655-66 |
1 | J:231980 Tomas-Roca L, Corral-San-Miguel R, Aroca P, Puelles L, Marin F, Crypto-rhombomeres of the mouse medulla oblongata, defined by molecular and morphological features. Brain Struct Funct. 2016 Mar;221(2):815-38 |
1* | J:39822 Zimmermann F, Rich IN, Mammalian homeobox B6 expression can be correlated with erythropoietin production sites and erythropoiesis during development, but not with hematopoietic or nonhematopoietic stem cell populations. Blood. 1997 Apr 15;89(8):2723-35 |
Hoxb8 homeobox B8 (Synonyms: Hox-2.4) | |
Results | Reference |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:134668 Holstege JC, de Graaff W, Hossaini M, Cano SC, Jaarsma D, van den Akker E, Deschamps J, Loss of Hoxb8 alters spinal dorsal laminae and sensory responses in mice. Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6338-43 |
1 | J:142008 Huang M, Huang T, Xiang Y, Xie Z, Chen Y, Yan R, Xu J, Cheng L, Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons. Dev Biol. 2008 Jul 2;322(2):394-405 |
1 | J:231980 Tomas-Roca L, Corral-San-Miguel R, Aroca P, Puelles L, Marin F, Crypto-rhombomeres of the mouse medulla oblongata, defined by molecular and morphological features. Brain Struct Funct. 2016 Mar;221(2):815-38 |
1* | J:39822 Zimmermann F, Rich IN, Mammalian homeobox B6 expression can be correlated with erythropoietin production sites and erythropoiesis during development, but not with hematopoietic or nonhematopoietic stem cell populations. Blood. 1997 Apr 15;89(8):2723-35 |
Hoxb9 homeobox B9 (Synonyms: Hox-2.5) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:225537 Zhang J, Taylor RJ, La Torre A, Wilken MS, Cox KE, Reh TA, Vetter ML, Ezh2 maintains retinal progenitor proliferation, transcriptional integrity, and the timing of late differentiation. Dev Biol. 2015 Jul 15;403(2):128-38 |
Hoxb13 homeobox B13 | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
Hoxc4 homeobox C4 (Synonyms: Hox-3.5) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:204667 Min H, Lee JY, Kim MH, Hoxc gene collinear expression and epigenetic modifications established during embryogenesis are maintained until after birth. Int J Biol Sci. 2013;9(9):960-5 |
2 | J:60124 Pitera JE, Smith VV, Thorogood P, Milla PJ, Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code. Gastroenterology. 1999 Dec;117(6):1339-51 |
1 | J:231980 Tomas-Roca L, Corral-San-Miguel R, Aroca P, Puelles L, Marin F, Crypto-rhombomeres of the mouse medulla oblongata, defined by molecular and morphological features. Brain Struct Funct. 2016 Mar;221(2):815-38 |
Hoxc5 homeobox C5 (Synonyms: Hox-3.4, Hox-6.2) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:204667 Min H, Lee JY, Kim MH, Hoxc gene collinear expression and epigenetic modifications established during embryogenesis are maintained until after birth. Int J Biol Sci. 2013;9(9):960-5 |
2 | J:60124 Pitera JE, Smith VV, Thorogood P, Milla PJ, Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code. Gastroenterology. 1999 Dec;117(6):1339-51 |
1 | J:231980 Tomas-Roca L, Corral-San-Miguel R, Aroca P, Puelles L, Marin F, Crypto-rhombomeres of the mouse medulla oblongata, defined by molecular and morphological features. Brain Struct Funct. 2016 Mar;221(2):815-38 |
Hoxc6 homeobox C6 (Synonyms: Hox-3.3, Hox-6.1) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:239872 Larsen BM, Hrycaj SM, Newman M, Li Y, Wellik DM, Mesenchymal Hox6 function is required for mouse pancreatic endocrine cell differentiation. Development. 2015 Nov 15;142(22):3859-68 |
1 | J:204667 Min H, Lee JY, Kim MH, Hoxc gene collinear expression and epigenetic modifications established during embryogenesis are maintained until after birth. Int J Biol Sci. 2013;9(9):960-5 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Hoxc8 homeobox C8 (Synonyms: D130011F21Rik, Hox-3.1) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:22469 Kanzler B, Viallet JP, Le Mouellic H, Boncinelli E, Duboule D, Dhouailly D, Differential expression of two different homeobox gene families during mouse tegument morphogenesis. Int J Dev Biol. 1994 Dec;38(4):633-40 |
1 | J:97489 Kwon Y, Shin J, Park HW, Kim MH, Dynamic expression pattern of Hoxc8 during mouse early embryogenesis. Anat Rec A Discov Mol Cell Evol Biol. 2005 Mar;283(1):187-92 |
1 | J:204667 Min H, Lee JY, Kim MH, Hoxc gene collinear expression and epigenetic modifications established during embryogenesis are maintained until after birth. Int J Biol Sci. 2013;9(9):960-5 |
Hoxc9 homeobox C9 (Synonyms: Hox-3.2) | |
Results | Reference |
1* | J:11610 Erselius JR, Goulding MD, Gruss P, Structure and expression pattern of the murine Hox-3.2 gene. Development. 1990 Oct;110(2):629-42 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:204667 Min H, Lee JY, Kim MH, Hoxc gene collinear expression and epigenetic modifications established during embryogenesis are maintained until after birth. Int J Biol Sci. 2013;9(9):960-5 |
1* | J:160194 Shaw L, Johnson PA, Kimber SJ, Gene expression profiling of the developing mouse kidney and embryo. In Vitro Cell Dev Biol Anim. 2010 Feb;46(2):155-65 |
Hoxc10 homeobox C10 (Synonyms: Hox-3.6) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:204667 Min H, Lee JY, Kim MH, Hoxc gene collinear expression and epigenetic modifications established during embryogenesis are maintained until after birth. Int J Biol Sci. 2013;9(9):960-5 |
Hoxc11 homeobox C11 (Synonyms: Hox-3.7) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:204667 Min H, Lee JY, Kim MH, Hoxc gene collinear expression and epigenetic modifications established during embryogenesis are maintained until after birth. Int J Biol Sci. 2013;9(9):960-5 |
Hoxc12 homeobox C12 (Synonyms: Hox-3.8) | |
Results | Reference |
1* | J:297683 Fernandez-Guerrero M, Yakushiji-Kaminatsui N, Lopez-Delisle L, Zdral S, Darbellay F, Perez-Gomez R, Bolt CC, Sanchez-Martin MA, Duboule D, Ros MA, Mammalian-specific ectodermal enhancers control the expression of Hoxc genes in developing nails and hair follicles. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30509-30519 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:204667 Min H, Lee JY, Kim MH, Hoxc gene collinear expression and epigenetic modifications established during embryogenesis are maintained until after birth. Int J Biol Sci. 2013;9(9):960-5 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Hoxc13 homeobox C13 (Synonyms: N) | |
Results | Reference |
1* | J:297683 Fernandez-Guerrero M, Yakushiji-Kaminatsui N, Lopez-Delisle L, Zdral S, Darbellay F, Perez-Gomez R, Bolt CC, Sanchez-Martin MA, Duboule D, Ros MA, Mammalian-specific ectodermal enhancers control the expression of Hoxc genes in developing nails and hair follicles. Proc Natl Acad Sci U S A. 2020 Dec 1;117(48):30509-30519 |
1 | J:356109 Ge W, Tan SJ, Wang SH, Li L, Sun XF, Shen W, Wang X, Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development. Theranostics. 2020;10(17):7581-7598 |
1 | J:45400 Godwin AR, Capecchi MR, Hoxc13 mutant mice lack external hair. Genes Dev. 1998 Jan 1;12(1):11-20 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:94541 Jonker L, Kist R, Aw A, Wappler I, Peters H, Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium. Mech Dev. 2004 Nov;121(11):1313-22 |
1 | J:204667 Min H, Lee JY, Kim MH, Hoxc gene collinear expression and epigenetic modifications established during embryogenesis are maintained until after birth. Int J Biol Sci. 2013;9(9):960-5 |
Hoxd1 homeobox D1 (Synonyms: Hox-4.9) | |
Results | Reference |
1 | J:37004 Dolle P, Izpisua-Belmonte JC, Brown JM, Tickle C, Duboule D, HOX-4 genes and the morphogenesis of mammalian genitalia. Genes Dev. 1991 Oct;5(10):1767-7 |
1* | J:2048 Frohman MA, Martin GR, Isolation and analysis of embryonic expression of Hox-4.9, a member of the murine labial-like gene family. Mech Dev. 1992 Jul;38(1):55-67 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
1* | J:74097 Wolf LV, Yeung JM, Doucette JR, Nazarali AJ, Coordinated expression of Hoxa2, Hoxd1 and Pax6 in the developing diencephalon. Neuroreport. 2001 Feb 12;12(2):329-33 |
Hoxd3 homeobox D3 (Synonyms: Hox-4.1, Hox-5.5) | |
Results | Reference |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
Hoxd3os1 homeobox D3, opposite strand 1 (Synonyms: 1700064D17Rik, 1700109F18Rik) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Hoxd4 homeobox D4 (Synonyms: Hox-4.2, Hox-5.1) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:60124 Pitera JE, Smith VV, Thorogood P, Milla PJ, Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code. Gastroenterology. 1999 Dec;117(6):1339-51 |
1 | J:231980 Tomas-Roca L, Corral-San-Miguel R, Aroca P, Puelles L, Marin F, Crypto-rhombomeres of the mouse medulla oblongata, defined by molecular and morphological features. Brain Struct Funct. 2016 Mar;221(2):815-38 |
Hoxd8 homeobox D8 (Synonyms: 4921540P06Rik, Hox-4.3, Hox-5.4) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
Hoxd9 homeobox D9 (Synonyms: Hox-4.4, Hox-5.2) | |
Results | Reference |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:54386 Khoa ND, Hasunuma T, Kobata T, Kato T, Nishioka K, Expression of murine HOXD9 during embryonic joint patterning and in human T lymphotropic virus type I tax transgenic mice with arthropathy resembling rheumatoid arthritis. Arthritis Rheum. 1999 Apr;42(4):686-96 |
Hoxd10 homeobox D10 (Synonyms: Hox-4.5, Hox-5.3) | |
Results | Reference |
1 | J:37004 Dolle P, Izpisua-Belmonte JC, Brown JM, Tickle C, Duboule D, HOX-4 genes and the morphogenesis of mammalian genitalia. Genes Dev. 1991 Oct;5(10):1767-7 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:54386 Khoa ND, Hasunuma T, Kobata T, Kato T, Nishioka K, Expression of murine HOXD9 during embryonic joint patterning and in human T lymphotropic virus type I tax transgenic mice with arthropathy resembling rheumatoid arthritis. Arthritis Rheum. 1999 Apr;42(4):686-96 |
1 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
Hoxd11 homeobox D11 (Synonyms: E230017H14Rik, Hox-4.6, Hox-5.4, Hox-5.5) | |
Results | Reference |
2* | J:75699 Albrecht AN, Schwabe GC, Stricker S, Boddrich A, Wanker EE, Mundlos S, The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:22469 Kanzler B, Viallet JP, Le Mouellic H, Boncinelli E, Duboule D, Dhouailly D, Differential expression of two different homeobox gene families during mouse tegument morphogenesis. Int J Dev Biol. 1994 Dec;38(4):633-40 |
1* | J:54386 Khoa ND, Hasunuma T, Kobata T, Kato T, Nishioka K, Expression of murine HOXD9 during embryonic joint patterning and in human T lymphotropic virus type I tax transgenic mice with arthropathy resembling rheumatoid arthritis. Arthritis Rheum. 1999 Apr;42(4):686-96 |
1 | J:264647 O'Brien LL, Guo Q, Bahrami-Samani E, Park JS, Hasso SM, Lee YJ, Fang A, Kim AD, Guo J, Hong TM, Peterson KA, Lozanoff S, Raviram R, Ren B, Fogelgren B, Smith AD, Valouev A, McMahon AP, Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies. PLoS Genet. 2018 Jan;14(1):e1007181 |
Hoxd12 homeobox D12 (Synonyms: Hox-4.7, Hox-5.6) | |
Results | Reference |
1* | J:75699 Albrecht AN, Schwabe GC, Stricker S, Boddrich A, Wanker EE, Mundlos S, The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1* | J:1778 Dolle P, Izpisua-Belmonte JC, Boncinelli E, Duboule D, The Hox-4.8 gene is localized at the 5' extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development. Mech Dev. 1991 Dec;36(1-2):3-13 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:54386 Khoa ND, Hasunuma T, Kobata T, Kato T, Nishioka K, Expression of murine HOXD9 during embryonic joint patterning and in human T lymphotropic virus type I tax transgenic mice with arthropathy resembling rheumatoid arthritis. Arthritis Rheum. 1999 Apr;42(4):686-96 |
Hoxd13 homeobox D13 (Synonyms: Hox-4.8, spdh) | |
Results | Reference |
2* | J:75699 Albrecht AN, Schwabe GC, Stricker S, Boddrich A, Wanker EE, Mundlos S, The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67 |
1 | J:356099 Amandio AR, Lopez-Delisle L, Bolt CC, Mascrez B, Duboule D, A complex regulatory landscape involved in the development of mammalian external genitals. Elife. 2020 Apr 17;9 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1* | J:1778 Dolle P, Izpisua-Belmonte JC, Boncinelli E, Duboule D, The Hox-4.8 gene is localized at the 5' extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development. Mech Dev. 1991 Dec;36(1-2):3-13 |
1 | J:37004 Dolle P, Izpisua-Belmonte JC, Brown JM, Tickle C, Duboule D, HOX-4 genes and the morphogenesis of mammalian genitalia. Genes Dev. 1991 Oct;5(10):1767-7 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1* | J:54386 Khoa ND, Hasunuma T, Kobata T, Kato T, Nishioka K, Expression of murine HOXD9 during embryonic joint patterning and in human T lymphotropic virus type I tax transgenic mice with arthropathy resembling rheumatoid arthritis. Arthritis Rheum. 1999 Apr;42(4):686-96 |
Hp haptoglobin (Synonyms: HP-1, preHP2, zonulin) | |
Results | Reference |
2* | J:42471 D'Armiento J, Dalal SS, Chada K, Tissue, temporal and inducible expression pattern of haptoglobin in mice. Gene. 1997 Aug 11;195(1):19-27 |
Hpn hepsin (Synonyms: Hlb320) | |
Results | Reference |
1* | J:180502 Torres-Rosado A, O'Shea KS, Tsuji A, Chou SH, Kurachi K, Hepsin, a putative cell-surface serine protease, is required for mammalian cell growth. Proc Natl Acad Sci U S A. 1993 Aug 1;90(15):7181-5 |
Hprt1 hypoxanthine phosphoribosyltransferase 1 (Synonyms: Hprt) | |
Results | Reference |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
1 | J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6 |
1 | J:190424 Kraemer N, Neubert G, Issa L, Ninnemann O, Seiler AE, Kaindl AM, Reference genes in the developing murine brain and in differentiating embryonic stem cells. Neurol Res. 2012 Sep;34(7):664-8 |
2 | J:341495 Mizukoshi T, Yamada S, Sakakibara SI, Spatiotemporal Regulation of De Novo and Salvage Purine Synthesis during Brain Development. eNeuro. 2023 Oct;10(10):ENEURO.0159-23.2023 |
Hpse heparanase (Synonyms: Hpa) | |
Results | Reference |
1 | J:175154 Brown AJ, Alicknavitch M, D'Souza SS, Daikoku T, Kirn-Safran CB, Marchetti D, Carson DD, Farach-Carson MC, Heparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formation. Bone. 2008 Oct;43(4):689-99 |
Hr lysine demethylase and nuclear receptor corepressor (Synonyms: ba, bldy, N, rh, rh-bmh) | |
Results | Reference |
2 | J:133064 Brancaz-Bouvier MV, Folco EJ, Salameire D, Romero Y, Iratni R, Nonchev S, The 'bald Mill Hill' mutation in the mouse is associated with an abnormal, mislocalized HR bmh protein. J Invest Dermatol. 2008 Feb;128(2):311-21 |
1* | J:57947 Cachon-Gonzalez MB, San-Jose I, Cano A, Vega JA, Garcia N, Freeman T, Schimmang T, Stoye JP, The hairless gene of the mouse: relationship of phenotypic effects with expression profile and genotype. Dev Dyn. 1999 Oct;216(2):113-26 |
Hras Harvey rat sarcoma virus oncogene (Synonyms: c-H-ras, c-rasHa, Ha-ras, Harvey-ras, H-ras, Hras-1, Hras1) | |
Results | Reference |
1 | J:7235 Muller R, Verma IM, Adamson ED, Expression of c-onc genes: c-fos transcripts accumulate to high levels during development of mouse placenta, yolk sac and amnion. EMBO J. 1983;2(5):679-84 |
1* | J:320537 Newlaczyl AU, Coulson JM, Prior IA, Quantification of spatiotemporal patterns of Ras isoform expression during development. Sci Rep. 2017 Jan 24;7:41297 |
3 | J:246653 Park JC, Jeong WJ, Kim MY, Min D, Choi KY, Retinoic-acid-mediated HRas stabilization induces neuronal differentiation of neural stem cells during brain development. J Cell Sci. 2016 Aug 01;129(15):2997-3007 |
1 | J:178367 Slamon DJ, Cline MJ, Expression of cellular oncogenes during embryonic and fetal development of the mouse. Proc Natl Acad Sci U S A. 1984 Nov;81(22):7141-5 |
Hrc histidine rich calcium binding protein | |
Results | Reference |
1* | J:97586 Hong S, Kim TW, Choi I, Woo JM, Oh J, Park WJ, Kim do H, Cho C, Complementary DNA cloning, genomic characterization and expression analysis of a mammalian gene encoding histidine-rich calcium binding protein. Biochim Biophys Acta. 2005 Mar 10;1727(3):188-96 |
Hrnr hornerin (Synonyms: 1110033K19Rik, A530063N20Rik, S100a18) | |
Results | Reference |
1* | J:198837 Cui CY, Klar J, Georgii-Heming P, Frojmark AS, Baig SM, Schlessinger D, Dahl N, Frizzled6 deficiency disrupts the differentiation process of nail development. J Invest Dermatol. 2013 Aug;133(8):1990-7 |
2* | J:73258 Makino T, Takaishi M, Morohashi M, Huh NH, Hornerin, a novel profilaggrin-like protein and differentiation-specific marker isolated from mouse skin. J Biol Chem. 2001 Dec 14;276(50):47445-52 |
Hs2st1 heparan sulfate 2-O-sulfotransferase 1 (Synonyms: Hs2st, mKIAA0448) | |
Results | Reference |
1 | J:169370 Conway CD, Howe KM, Nettleton NK, Price DJ, Mason JO, Pratt T, Heparan sulfate sugar modifications mediate the functions of slits and other factors needed for mouse forebrain commissure development. J Neurosci. 2011 Feb 9;31(6):1955-70 |
Hs3st2 heparan sulfate (glucosamine) 3-O-sulfotransferase 2 (Synonyms: 6430516N12Rik, A830061E14Rik) | |
Results | Reference |
2 | J:208752 Hasegawa H, Wang F, Visualizing mechanosensory endings of TrkC-expressing neurons in HS3ST-2-hPLAP mice. J Comp Neurol. 2008 Dec 1;511(4):543-56 |
Hs6st1 heparan sulfate 6-O-sulfotransferase 1 (Synonyms: 6OST1) | |
Results | Reference |
1 | J:169370 Conway CD, Howe KM, Nettleton NK, Price DJ, Mason JO, Pratt T, Heparan sulfate sugar modifications mediate the functions of slits and other factors needed for mouse forebrain commissure development. J Neurosci. 2011 Feb 9;31(6):1955-70 |
Hs6st2 heparan sulfate 6-O-sulfotransferase 2 (Synonyms: 6OST2) | |
Results | Reference |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Hsbp1 heat shock factor binding protein 1 (Synonyms: 0610007A03Rik) | |
Results | Reference |
1 | J:139182 Farooqui-Kabir SR, Diss JK, Henderson D, Marber MS, Latchman DS, Budhram-Mahadeo V, Heads RJ, Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression. Cell Stress Chaperones. 2008 Sep;13(3):297-312 |
Hsd3b hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase cluster | |
Results | Reference |
1 | J:292639 Cen C, Chen M, Zhou J, Zhang L, Duo S, Jiang L, Hou X, Gao F, Inactivation of Wt1 causes pre-granulosa cell to steroidogenic cell transformation and defect of ovary development. Biol Reprod. 2020 Jun 23;103(1):60-69 |
1 | J:134687 Chang H, Gao F, Guillou F, Taketo MM, Huff V, Behringer RR, Wt1 negatively regulates {beta}-catenin signaling during testis development. Development. 2008 May;135(10):1875-85 |
1 | J:335572 Chen Z, Lei Y, Finnell RH, Ding Y, Su Z, Wang Y, Xie H, Chen F, Whole-exome sequencing study of hypospadias. iScience. 2023 May 19;26(5):106663 |
1 | J:189572 Huang CC, Liu C, Yao HH, Investigating the role of adrenal cortex in organization and differentiation of the adrenal medulla in mice. Mol Cell Endocrinol. 2012 Sep 25;361(1-2):165-71 |
1* | J:163555 Huang CC, Yao HH, Inactivation of Dicer1 in Steroidogenic factor 1-positive cells reveals tissue-specific requirement for Dicer1 in adrenal, testis, and ovary. BMC Dev Biol. 2010;10:66 |
1 | J:188056 Jameson SA, Lin YT, Capel B, Testis development requires the repression of Wnt4 by Fgf signaling. Dev Biol. 2012 Oct 1;370(1):24-32 |
1 | J:227517 Koizumi M, Oyama K, Yamakami Y, Kida T, Satoh R, Kato S, Hidema S, Oe T, Goto T, Clevers H, Nawa A, Nishimori K, Lgr4 controls specialization of female gonads in mice. Biol Reprod. 2015 Oct;93(4):90 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1 | J:225050 Miyabayashi K, Katoh-Fukui Y, Ogawa H, Baba T, Shima Y, Sugiyama N, Kitamura K, Morohashi K, Aristaless related homeobox gene, Arx, is implicated in mouse fetal Leydig cell differentiation possibly through expressing in the progenitor cells. PLoS One. 2013;8(6):e68050 |
1* | J:72502 Perez-Armendariz EM, Lamoyi E, Mason JI, Cisneros-Armas D, Luu-The V, Bravo Moreno JF, Developmental regulation of connexin 43 expression in fetal mouse testicular cells. Anat Rec. 2001 Nov 1;264(3):237-46 |
1 | J:197599 Pitetti JL, Calvel P, Romero Y, Conne B, Truong V, Papaioannou MD, Schaad O, Docquier M, Herrera PL, Wilhelm D, Nef S, Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice. PLoS Genet. 2013;9(1):e1003160 |
1* | J:326026 Prokopuk L, Jarred EG, Blucher RO, McLaughlin EA, Stringer JM, Western PS, An essential role for Polycomb Repressive Complex 2 in the mouse ovary. Reproduction. 2022 Feb 17;163(3):167-182 |
1* | J:308609 Sararols P, Stevant I, Neirijnck Y, Rebourcet D, Darbey A, Curley MK, Kuhne F, Dermitzakis E, Smith LB, Nef S, Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells. Front Cell Dev Biol. 2021;9:695546 |
1 | J:220734 Zhang L, Chen M, Wen Q, Li Y, Wang Y, Wang Y, Qin Y, Cui X, Yang L, Huff V, Gao F, Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4003-8 |
Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 (Synonyms: D3Ertd383e) | |
Results | Reference |
1* | J:324263 Aksel S, Cao M, Derpinghaus A, Baskin LS, Cunha GR, Ontogeny of mouse Sertoli, Leydig and peritubular myoid cells from embryonic day 10 to adulthood. Differentiation. 2022 Mar 7; |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:307764 Kothandapani A, Larsen MC, Lee J, Jorgensen JS, Jefcoate CR, Distinctive functioning of STARD1 in the fetal Leydig cells compared to adult Leydig and adrenal cells. Impact of Hedgehog signaling via the primary cilium. Mol Cell Endocrinol. 2021 Jul 1;531:111265 |
1* | J:21125 Lee CH, Taketo T, Normal onset, but prolonged expression, of Sry gene in the B6.YDOM sex-reversed mouse gonad. Dev Biol. 1994 Oct;165(2):442-52 |
3 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
2 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1 | J:205146 Praktiknjo SD, Llamas B, Scott-Boyer MP, Picard S, Robert F, Langlais D, Haibe-Kains B, Faubert D, Silversides DW, Deschepper CF, Novel effects of chromosome Y on cardiac regulation, chromatin remodeling, and neonatal programming in male mice. Endocrinology. 2013 Dec;154(12):4746-56 |
1 | J:286995 Wang YQ, Cheng JM, Wen Q, Tang JX, Li J, Chen SR, Liu YX, An exploration of the role of Sertoli cells on fetal testis development using cell ablation strategy. Mol Reprod Dev. 2020 Feb;87(2):223-230 |
1 | J:251156 Wen Q, Wang Y, Tang J, Cheng CY, Liu YX, Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development. PLoS One. 2016;11(12):e0167920 |
Hsd3b6 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 (Synonyms: 3beta-HSD VI) | |
Results | Reference |
1* | J:324263 Aksel S, Cao M, Derpinghaus A, Baskin LS, Cunha GR, Ontogeny of mouse Sertoli, Leydig and peritubular myoid cells from embryonic day 10 to adulthood. Differentiation. 2022 Mar 7; |
Hsd11b1 hydroxysteroid 11-beta dehydrogenase 1 (Synonyms: 11beta-HSD-1, 11beta-hydroxysteroid dehydrogenase type 1) | |
Results | Reference |
1 | J:89625 Speirs HJ, Seckl JR, Brown RW, Ontogeny of glucocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type-1 gene expression identifies potential critical periods of glucocorticoid susceptibility during development. J Endocrinol. 2004 Apr;181(1):105-16 |
1 | J:80418 Thompson A, Han VK, Yang K, Spatial and temporal patterns of expression of 11beta-hydroxysteroid dehydrogenase types 1 and 2 messenger RNA and glucocorticoid receptor protein in the murine placenta and uterus during late pregnancy. Biol Reprod. 2002 Dec;67(6):1708-18 |
1 | J:90284 Thompson A, Han VK, Yang K, Differential expression of 11beta-hydroxysteroid dehydrogenase types 1 and 2 mRNA and glucocorticoid receptor protein during mouse embryonic development. J Steroid Biochem Mol Biol. 2004 Apr;88(4-5):367-75 |
Hsd11b2 hydroxysteroid 11-beta dehydrogenase 2 (Synonyms: 11(beta)-HSD2, 11HSD2) | |
Results | Reference |
1 | J:321162 Boix J, Carceller E, Sevilla LM, Marcos-Garces V, Perez P, The mineralocorticoid receptor plays a transient role in mouse skin development. Exp Dermatol. 2016 Jan;25(1):69-71 |
1 | J:80418 Thompson A, Han VK, Yang K, Spatial and temporal patterns of expression of 11beta-hydroxysteroid dehydrogenase types 1 and 2 messenger RNA and glucocorticoid receptor protein in the murine placenta and uterus during late pregnancy. Biol Reprod. 2002 Dec;67(6):1708-18 |
1 | J:90284 Thompson A, Han VK, Yang K, Differential expression of 11beta-hydroxysteroid dehydrogenase types 1 and 2 mRNA and glucocorticoid receptor protein during mouse embryonic development. J Steroid Biochem Mol Biol. 2004 Apr;88(4-5):367-75 |
Hsd17b2 hydroxysteroid (17-beta) dehydrogenase 2 (Synonyms: 17 HSD type 2) | |
Results | Reference |
1 | J:159267 Plante J, Simard M, Rantakari P, Cote M, Provost PR, Poutanen M, Tremblay Y, Epithelial cells are the major site of hydroxysteroid (17beta) dehydrogenase 2 and androgen receptor expression in fetal mouse lungs during the period overlapping the surge of surfactant. J Steroid Biochem Mol Biol. 2009 Nov;117(4-5):139-45 |
1 | J:161760 Provost PR, Simard M, Tremblay Y, A link between lung androgen metabolism and the emergence of mature epithelial type II cells. Am J Respir Crit Care Med. 2004 Aug 1;170(3):296-305 |
1* | J:106945 Tremblay Y, Provost PR, 17beta-HSD type 5 expression and the emergence of differentiated epithelial Type II cells in fetal lung: A novel role for androgen during the surge of surfactant. Mol Cell Endocrinol. 2006 Mar 27;248(1-2):118-25 |
Hsd17b3 hydroxysteroid (17-beta) dehydrogenase 3 (Synonyms: 17(beta)HSD type 3) | |
Results | Reference |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1 | J:161760 Provost PR, Simard M, Tremblay Y, A link between lung androgen metabolism and the emergence of mature epithelial type II cells. Am J Respir Crit Care Med. 2004 Aug 1;170(3):296-305 |
Hsd17b11 hydroxysteroid (17-beta) dehydrogenase 11 (Synonyms: 17beta-HSD11, Dhrs8, Pan1b, retSDR2) | |
Results | Reference |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Hsd17b12 hydroxysteroid (17-beta) dehydrogenase 12 (Synonyms: 2610510O05Rik, keratoadhesin, keratonectin, KIK-I) | |
Results | Reference |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Hsf1 heat shock factor 1 (Synonyms: heat shock transcription factor 1) | |
Results | Reference |
1 | J:331267 de Thonel A, Ahlskog JK, Daupin K, Dubreuil V, Berthelet J, Chaput C, Pires G, Leonetti C, Abane R, Barris LC, Leray I, Aalto AL, Naceri S, Cordonnier M, Benasolo C, Sanial M, Duchateau A, Vihervaara A, Puustinen MC, Miozzo F, Fergelot P, Lebigot E, Verloes A, Gressens P, Lacombe D, Gobbo J, Garrido C, Westerheide SD, David L, Petitjean M, Taboureau O, Rodrigues-Lima F, Passemard S, Saberan-Djoneidi D, Nguyen L, Lancaster M, Sistonen L, Mezger V, CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder. Nat Commun. 2022 Nov 16;13(1):7002 |
1* | J:74044 Eriksson M, Jokinen E, Sistonen L, Leppa S, Heat shock factor 2 is activated during mouse heart development. Int J Dev Biol. 2000 Aug;44(5):471-7 |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
Hsf2 heat shock factor 2 | |
Results | Reference |
1 | J:331267 de Thonel A, Ahlskog JK, Daupin K, Dubreuil V, Berthelet J, Chaput C, Pires G, Leonetti C, Abane R, Barris LC, Leray I, Aalto AL, Naceri S, Cordonnier M, Benasolo C, Sanial M, Duchateau A, Vihervaara A, Puustinen MC, Miozzo F, Fergelot P, Lebigot E, Verloes A, Gressens P, Lacombe D, Gobbo J, Garrido C, Westerheide SD, David L, Petitjean M, Taboureau O, Rodrigues-Lima F, Passemard S, Saberan-Djoneidi D, Nguyen L, Lancaster M, Sistonen L, Mezger V, CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder. Nat Commun. 2022 Nov 16;13(1):7002 |
2* | J:74044 Eriksson M, Jokinen E, Sistonen L, Leppa S, Heat shock factor 2 is activated during mouse heart development. Int J Dev Biol. 2000 Aug;44(5):471-7 |
Hsf2bp heat shock transcription factor 2 binding protein (Synonyms: 4932437G14Rik) | |
Results | Reference |
1 | J:273173 Zhang J, Fujiwara Y, Yamamoto S, Shibuya H, A meiosis-specific BRCA2 binding protein recruits recombinases to DNA double-strand breaks to ensure homologous recombination. Nat Commun. 2019 Feb 13;10(1):722 |
Hsf4 heat shock transcription factor 4 (Synonyms: ldis1) | |
Results | Reference |
1 | J:350084 Zhang L, Liu X, Li W, Liu K, Zhang J, Liu X, Wang J, Integrative transcriptomic profiling of ncRNAs and mRNAs in developing mouse lens. Front Genet. 2024;15:1405715 |
Hsf5 heat shock transcription factor family member 5 (Synonyms: LOC327992) | |
Results | Reference |
1 | J:347775 Yoshimura S, Shimada R, Kikuchi K, Kawagoe S, Abe H, Iisaka S, Fujimura S, Yasunaga KI, Usuki S, Tani N, Ohba T, Kondoh E, Saio T, Araki K, Ishiguro KI, Atypical heat shock transcription factor HSF5 is critical for male meiotic prophase under non-stress conditions. Nat Commun. 2024 Apr 29;15(1):3330 |
Hsp90aa1 heat shock protein 90, alpha (cytosolic), class A member 1 (Synonyms: hsp4, Hsp86-1, Hsp89, Hsp90, Hspca) | |
Results | Reference |
1 | J:356915 Ichiyanagi T, Ichiyanagi K, Ogawa A, Kuramochi-Miyagawa S, Nakano T, Chuma S, Sasaki H, Udono H, HSP90alpha plays an important role in piRNA biogenesis and retrotransposon repression in mouse. Nucleic Acids Res. 2014 Oct 29;42(19):11903-11 |
1* | J:33469 Jaskoll T, Choy HA, Melnick M, The glucocorticoid-glucocorticoid receptor signal transduction pathway, transforming growth factor-beta, and embryonic mouse lung development in vivo. Pediatr Res. 1996 May;39(5):749-59 |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
1* | J:31372 Tanaka Y, Kobayashi K, Kita M, Kinoshita S, Imanishi J, Messenger RNA expression of heat shock proteins (HSPs) during ocular development. Curr Eye Res. 1995 Dec;14(12):1125-33 |
1* | J:80729 Vanmuylder N, Werry-Huet A, Rooze M, Louryan S, Heat shock protein HSP86 expression during mouse embryo development, especially in the germ-line. Anat Embryol (Berl). 2002 Jul;205(4):301-6 |
Hsp90ab1 heat shock protein 90 alpha (cytosolic), class B member 1 (Synonyms: C81438, Hsp84, Hsp84-1, Hsp90, Hspcb) | |
Results | Reference |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
1* | J:31372 Tanaka Y, Kobayashi K, Kita M, Kinoshita S, Imanishi J, Messenger RNA expression of heat shock proteins (HSPs) during ocular development. Curr Eye Res. 1995 Dec;14(12):1125-33 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Hsp90b1 heat shock protein 90, beta (Grp94), member 1 (Synonyms: 90 kDa, endoplasmin, ERp99, gp96, GRP94, Targ2, Tra-1, Tra1, tumor rejection antigen (gp96) 1) | |
Results | Reference |
1 | J:257425 Kim DS, Song L, Wang J, Wu H, Gu G, Sugi Y, Li Z, Wang H, GRP94 Is an Essential Regulator of Pancreatic beta-Cell Development, Mass, and Function in Male Mice. Endocrinology. 2018 Feb 1;159(2):1062-1073 |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
1 | J:128422 Zhang X, Szabo E, Michalak M, Opas M, Endoplasmic reticulum stress during the embryonic development of the central nervous system in the mouse. Int J Dev Neurosci. 2007 Nov;25(7):455-63 |
Hspa1b heat shock protein 1B (Synonyms: hsp68, Hsp70-1, Hsp70.1, HSP70B1) | |
Results | Reference |
2* | J:74044 Eriksson M, Jokinen E, Sistonen L, Leppa S, Heat shock factor 2 is activated during mouse heart development. Int J Dev Biol. 2000 Aug;44(5):471-7 |
1* | J:33469 Jaskoll T, Choy HA, Melnick M, The glucocorticoid-glucocorticoid receptor signal transduction pathway, transforming growth factor-beta, and embryonic mouse lung development in vivo. Pediatr Res. 1996 May;39(5):749-59 |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
1* | J:31372 Tanaka Y, Kobayashi K, Kita M, Kinoshita S, Imanishi J, Messenger RNA expression of heat shock proteins (HSPs) during ocular development. Curr Eye Res. 1995 Dec;14(12):1125-33 |
Hspa2 heat shock protein 2 (Synonyms: 70kDa, Hsp70-2) | |
Results | Reference |
1 | J:30591 Murashov AK, Wolgemuth DJ, Distinct transcripts are recognized by sense and antisense riboprobes for a member of the murine HSP70 gene family, HSP70.2, in various reproductive tissues. Mol Reprod Dev. 1996 Jan;43(1):17-24 |
Hspa4 heat shock protein 4 (Synonyms: 70kDa, APG-2, Hsp110, Hsp70RY) | |
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2 | J:231873 Mohamed BA, Barakat AZ, Held T, Elkenani M, Muhlfeld C, Manner J, Adham IM, Respiratory distress and early neonatal lethality in Hspa4l/Hspa4 double-mutant mice. Am J Respir Cell Mol Biol. 2014 Apr;50(4):817-24 |
Hspa5 heat shock protein 5 (Synonyms: 78kDa, baffled, Bip, D2Wsu141e, D2Wsu17e, Grp78, Hsce70, mBiP, Sez7, XAP-1 antigen) | |
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1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
2 | J:158314 Firtina Z, Danysh BP, Bai X, Gould DB, Kobayashi T, Duncan MK, Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract. J Biol Chem. 2009 Dec 18;284(51):35872-84 |
2* | J:168632 Firtina Z, Duncan MK, Unfolded Protein Response (UPR) is activated during normal lens development. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):135-43 |
1* | J:78912 Hellstrom M, Gerhardt H, Kalen M, Li X, Eriksson U, Wolburg H, Betsholtz C, Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol. 2001 Apr 30;153(3):543-53 |
1 | J:211963 Kawakami T, Yoshimi M, Kadota Y, Inoue M, Sato M, Suzuki S, Prolonged endoplasmic reticulum stress alters placental morphology and causes low birth weight. Toxicol Appl Pharmacol. 2014 Mar 1;275(2):134-44 |
1* | J:93233 Mao C, Dong D, Little E, Luo S, Lee AS, Transgenic mouse model for monitoring endoplasmic reticulum stress in vivo. Nat Med. 2004 Oct;10(10):1013-4 |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
1 | J:203031 Rainger J, Keighren M, Keene DR, Charbonneau NL, Rainger JK, Fisher M, Mella S, Huang JT, Rose L, van't Hof R, Sakai LY, Jackson IJ, FitzPatrick DR, A Trans-Acting protein effect causes severe eye malformation in the Mp mouse. PLoS Genet. 2013;9(12):e1003998 |
1* | J:170629 Ravindran S, Gao Q, Ramachandran A, Blond S, Predescu SA, George A, Stress Chaperone GRP-78 Functions in Mineralized Matrix Formation. J Biol Chem. 2011 Mar 18;286(11):8729-39 |
1* | J:316597 Ravindran S, Gao Q, Ramachandran A, Sundivakkam P, Tiruppathi C, George A, Expression and distribution of grp-78/bip in mineralizing tissues and mesenchymal cells. Histochem Cell Biol. 2012 Jul;138(1):113-25 |
1 | J:158241 Saito A, Hino S, Murakami T, Kanemoto S, Kondo S, Saitoh M, Nishimura R, Yoneda T, Furuichi T, Ikegawa S, Ikawa M, Okabe M, Imaizumi K, Regulation of endoplasmic reticulum stress response by a BBF2H7-mediated Sec23a pathway is essential for chondrogenesis. Nat Cell Biol. 2009 Oct;11(10):1197-204 |
1 | J:206302 Saito A, Kanemoto S, Zhang Y, Asada R, Hino K, Imaizumi K, Chondrocyte proliferation regulated by secreted luminal domain of ER stress transducer BBF2H7/CREB3L2. Mol Cell. 2014 Jan 9;53(1):127-39 |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
1 | J:342871 Xiang J, Pompetti AJ, Faranda AP, Wang Y, Novo SG, Li DW, Duncan MK, ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment. Cells. 2023 Nov 16;12(22) |
1 | J:128422 Zhang X, Szabo E, Michalak M, Opas M, Endoplasmic reticulum stress during the embryonic development of the central nervous system in the mouse. Int J Dev Neurosci. 2007 Nov;25(7):455-63 |
Hspa8 heat shock protein 8 (Synonyms: 2410008N15Rik, Hsc70, Hsc71, Hsc73, Hsp73) | |
Results | Reference |
1* | J:74044 Eriksson M, Jokinen E, Sistonen L, Leppa S, Heat shock factor 2 is activated during mouse heart development. Int J Dev Biol. 2000 Aug;44(5):471-7 |
1* | J:31372 Tanaka Y, Kobayashi K, Kita M, Kinoshita S, Imanishi J, Messenger RNA expression of heat shock proteins (HSPs) during ocular development. Curr Eye Res. 1995 Dec;14(12):1125-33 |
Hspb1 heat shock protein 1 (Synonyms: Hsp25) | |
Results | Reference |
1 | J:65871 Armstrong CL, Krueger-Naug AM, Currie RW, Hawkes R, Expression of heat-shock protein hsp25 in mouse purkinje cells during development reveals novel features of cerebellar compartmentation. J Comp Neurol. 2001 Jan 1;429(1):7-21 |
1 | J:69288 Armstrong CL, Krueger-Naug AM, Currie RW, Hawkes R, Constitutive expression of heat shock protein HSP25 in the central nervous system of the developing and adult mouse. J Comp Neurol. 2001 Jun 4;434(3):262-74 |
2* | J:74044 Eriksson M, Jokinen E, Sistonen L, Leppa S, Heat shock factor 2 is activated during mouse heart development. Int J Dev Biol. 2000 Aug;44(5):471-7 |
2 | J:122775 O'Shaughnessy RF, Welti JC, Cooke JC, Avilion AA, Monks B, Birnbaum MJ, Byrne C, AKT-dependent HspB1 (Hsp27) activity in epidermal differentiation. J Biol Chem. 2007 Jun 8;282(23):17297-305 |
1 | J:82153 Shimada M, Yamamoto M, Wakayama T, Iseki S, Amano O, Different expression of 25-kDa heat-shock protein (Hsp25) in Meckel's cartilage compared with other cartilages in the mouse. Anat Embryol (Berl). 2003 Feb;206(3):163-73 |
Hspb7 heat shock protein family, member 7 (cardiovascular) (Synonyms: cvHsp, Hsp25-2) | |
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1 | J:246267 Juo LY, Liao WC, Shih YL, Yang BY, Liu AB, Yan YT, HSPB7 interacts with dimerized FLNC and its absence results in progressive myopathy in skeletal muscles. J Cell Sci. 2016 Apr 15;129(8):1661-70 |
1 | J:244557 Liao WC, Juo LY, Shih YL, Chen YH, Yan YT, HSPB7 prevents cardiac conduction system defect through maintaining intercalated disc integrity. PLoS Genet. 2017 Aug;13(8):e1006984 |
Hspb8 heat shock protein 8 (Synonyms: Cryac, D5Ucla4, E2IG1, H11, H11K, HSP20-like, HSP22) | |
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1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Hspbap1 Hspb associated protein 1 (Synonyms: 3830421G21Rik) | |
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1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
Hspd1 heat shock protein 1 (chaperonin) (Synonyms: Hsp60) | |
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1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
1* | J:31372 Tanaka Y, Kobayashi K, Kita M, Kinoshita S, Imanishi J, Messenger RNA expression of heat shock proteins (HSPs) during ocular development. Curr Eye Res. 1995 Dec;14(12):1125-33 |
Hspg2 perlecan (heparan sulfate proteoglycan 2) (Synonyms: Pcn, per, perlecan, Plc) | |
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1 | J:175154 Brown AJ, Alicknavitch M, D'Souza SS, Daikoku T, Kirn-Safran CB, Marchetti D, Carson DD, Farach-Carson MC, Heparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formation. Bone. 2008 Oct;43(4):689-99 |
1 | J:335626 Castillo V, Diaz-Astudillo P, Corrales-Orovio R, San Martin S, Egana JT, Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin. Cells. 2023 Apr 22;12(9) |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
3* | J:227060 Fujikawa K, Yokohama-Tamaki T, Morita T, Baba O, Qin C, Shibata S, An in situ hybridization study of perlecan, DMP1, and MEPE in developing condylar cartilage of the fetal mouse mandible and limb bud cartilage. Eur J Histochem. 2015;59(3):2553 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1* | J:36833 Joseph SJ, Ford MD, Barth C, Portbury S, Bartlett PF, Nurcombe V , Greferath U, A proteoglycan that activates fibroblast growth factors during early neuronal development is a perlecan variant. Development. 1996 Nov;122(11):3443-52 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1* | J:353621 Patel VN, Aure MH, Choi SH, Ball JR, Lane ED, Wang Z, Xu Y, Zheng C, Liu X, Martin D, Pailin JY, Prochazkova M, Kulkarni AB, van Kuppevelt TH, Ambudkar IS, Liu J, Hoffman MP, Specific 3-O-sulfated heparan sulfate domains regulate salivary gland basement membrane metabolism and epithelial differentiation. Nat Commun. 2024 Aug 31;15(1):7584 |
1 | J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10) |
1 | J:236386 Xu X, Li Z, Leng Y, Neu CP, Calve S, Knockdown of the pericellular matrix molecule perlecan lowers in situ cell and matrix stiffness in developing cartilage. Dev Biol. 2016 Oct 15;418(2):242-7 |
Htr1a 5-hydroxytryptamine (serotonin) receptor 1A (Synonyms: 5-HT1A receptor, Gpcr18) | |
Results | Reference |
1* | J:111755 Bonnin A, Peng W, Hewlett W, Levitt P, Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development. Neuroscience. 2006;141(2):781-794 |
Htr1b 5-hydroxytryptamine (serotonin) receptor 1B (Synonyms: 5-HT<1B> receptor, 5-HT1B receptor, 5HT1B receptor) | |
Results | Reference |
1* | J:111755 Bonnin A, Peng W, Hewlett W, Levitt P, Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development. Neuroscience. 2006;141(2):781-794 |
1* | J:121833 Bonnin A, Torii M, Wang L, Rakic P, Levitt P, Serotonin modulates the response of embryonic thalamocortical axons to netrin-1. Nat Neurosci. 2007 May;10(5):588-97 |
Htr1d 5-hydroxytryptamine (serotonin) receptor 1D (Synonyms: Gpcr14, Htr1db) | |
Results | Reference |
1* | J:111755 Bonnin A, Peng W, Hewlett W, Levitt P, Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development. Neuroscience. 2006;141(2):781-794 |
1* | J:121833 Bonnin A, Torii M, Wang L, Rakic P, Levitt P, Serotonin modulates the response of embryonic thalamocortical axons to netrin-1. Nat Neurosci. 2007 May;10(5):588-97 |
Htr1f 5-hydroxytryptamine (serotonin) receptor 1F (Synonyms: Htr1eb) | |
Results | Reference |
1* | J:111755 Bonnin A, Peng W, Hewlett W, Levitt P, Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development. Neuroscience. 2006;141(2):781-794 |
Htr5b 5-hydroxytryptamine (serotonin) receptor 5B | |
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1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Htr6 5-hydroxytryptamine (serotonin) receptor 6 (Synonyms: 5-HT6) | |
Results | Reference |
1* | J:215912 Jacobshagen M, Niquille M, Chaumont-Dubel S, Marin P, Dayer A, The serotonin 6 receptor controls neuronal migration during corticogenesis via a ligand-independent Cdk5-dependent mechanism. Development. 2014 Sep;141(17):3370-7 |
Htra1 HtrA serine peptidase 1 (Synonyms: HtrA1, insulin-like growth factor binding protein 5 protease, L56, Prss11, RSPP11) | |
Results | Reference |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Htt huntingtin (Synonyms: C430023I11Rik, HD, Hdh, htt, huntingtin, IT15) | |
Results | Reference |
1* | J:274711 Niewiadomska-Cimicka A, Krzyzosiak A, Ye T, Podlesny-Drabiniok A, Dembele D, Dolle P, Krezel W, Genome-wide Analysis of RARbeta Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington's Disease and Other Neurodegenerative Disorders. Mol Neurobiol. 2017 Jul;54(5):3859-3878 |
Hus1 HUS1 checkpoint clamp component | |
Results | Reference |
1* | J:52457 Weiss RS, Kostrub CF, Enoch T, Leder P, Mouse Hus1, a homolog of the Schizosaccharomyces pombe hus1+ cell cycle checkpoint gene. Genomics. 1999 Jul 1;59(1):32-9 |
Hyal1 hyaluronoglucosaminidase 1 (Synonyms: Hyal-1) | |
Results | Reference |
1* | J:346912 Huang H, Hu X, Wu J, Song C, Tian Z, Jiang B, Hyaluronan degradation by HYAL2 is essential for odontoblastic differentiation and migration of mouse dental papilla cells. Matrix Biol. 2024 Mar 13; |
Hyal2 hyaluronoglucosaminidase 2 | |
Results | Reference |
1* | J:170267 Chaignat E, Yahya-Graison EA, Henrichsen CN, Chrast J, Schutz F, Pradervand S, Reymond A, Copy number variation modifies expression time courses. Genome Res. 2011 Jan;21(1):106-13 |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1* | J:346912 Huang H, Hu X, Wu J, Song C, Tian Z, Jiang B, Hyaluronan degradation by HYAL2 is essential for odontoblastic differentiation and migration of mouse dental papilla cells. Matrix Biol. 2024 Mar 13; |
Hydin HYDIN, axonemal central pair apparatus protein (Synonyms: 1700034M11Rik, 4930545D19Rik, hy-3, hy3, hyrh) | |
Results | Reference |
1 | J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6 |
Iapp islet amyloid polypeptide (Synonyms: amylin) | |
Results | Reference |
1 | J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461 |
Ibsp integrin binding sialoprotein (Synonyms: bone sialoprotein, Bsp, BSP, Bsp2) | |
Results | Reference |
1 | J:90567 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 2004 May 1;18(9):1072-87 |
1 | J:188176 Caparros-Martin JA, Valencia M, Reytor E, Pacheco M, Fernandez M, Perez-Aytes A, Gean E, Lapunzina P, Peters H, Goodship JA, Ruiz-Perez VL, The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia. Hum Mol Genet. 2013 Jan 1;22(1):124-39 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1* | J:195901 Ehlen H, Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues. J Bone Miner Res. 2013;28(2):246-59 |
1 | J:217210 Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H, Loss of Tbx1 induces bone phenotypes similar to cleidocranial dysplasia. Hum Mol Genet. 2015 Jan 15;24(2):424-35 |
1 | J:185118 Galli GG, Honnens de Lichtenberg K, Carrara M, Hans W, Wuelling M, Mentz B, Multhaupt HA, Fog CK, Jensen KT, Rappsilber J, Vortkamp A, Coulton L, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Calogero RA, Couchman JR, Lund AH, Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone. PLoS Genet. 2012 May;8(5):e1002711 |
1 | J:111426 Ganss B, Kobayashi H, The zinc finger transcription factor Zfp60 is a negative regulator of cartilage differentiation. J Bone Miner Res. 2002 Dec;17(12):2151-60 |
1 | J:217455 Holm E, Aubin JE, Hunter GK, Beier F, Goldberg HA, Loss of bone sialoprotein leads to impaired endochondral bone development and mineralization. Bone. 2015 Feb;71:145-54 |
1 | J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132 |
1* | J:54095 Inada M, Yasui T, Nomura S, Miyake S, Deguchi K, Himeno M, Sato M, Yamagiwa H, Kimura T, Yasui N, Ochi T, Endo N, Kitamura Y, Kishimoto T, Komori T, Maturational disturbance of chondrocytes in Cbfa1-deficient mice. Dev Dyn. 1999 Apr;214(4):279-90 |
1 | J:153633 Ito T, Yadav N, Lee J, Furumatsu T, Yamashita S, Yoshida K, Taniguchi N, Hashimoto M, Tsuchiya M, Ozaki T, Lotz M, Bedford MT, Asahara H, Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC Dev Biol. 2009;9:47 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:143588 Kamiya N, Ye L, Kobayashi T, Mochida Y, Yamauchi M, Kronenberg HM, Feng JQ, Mishina Y, BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development. 2008 Nov;135(22):3801-11 |
1 | J:152843 Luo J, Zhou W, Zhou X, Li D, Weng J, Yi Z, Cho SG, Li C, Yi T, Wu X, Li XY, de Crombrugghe B, Hook M, Liu M, Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development. 2009 Aug;136(16):2747-56 |
1 | J:296737 Matsuura VKSK, Yoshida CA, Komori H, Sakane C, Yamana K, Jiang Q, Komori T, Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice. Int J Mol Sci. 2020 Apr 12;21(8):2682 |
1* | J:153103 Mikura A, Okuhara S, Saito M, Ota M, Ueda K, Iseki S, Association of tenascin-W expression with mineralization in mouse calvarial development. Congenit Anom (Kyoto). 2009 Jun;49(2):77-84 |
1 | J:145520 Moenning A, Jager R, Egert A, Kress W, Wardelmann E, Schorle H, Sustained platelet-derived growth factor receptor alpha signaling in osteoblasts results in craniosynostosis by overactivating the phospholipase C-gamma pathway. Mol Cell Biol. 2009 Feb;29(3):881-91 |
1* | J:74344 Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B, The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 2002 Jan 11;108(1):17-29 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1 | J:258274 Patra D, DeLassus E, Mueller J, Abou-Ezzi G, Sandell LJ, Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice. Biol Open. 2018 Feb 22;7(2):bio032094 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
1 | J:299239 Qin X, Jiang Q, Nagano K, Moriishi T, Miyazaki T, Komori H, Ito K, Mark KV, Sakane C, Kaneko H, Komori T, Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts. PLoS Genet. 2020 Nov;16(11):e1009169 |
1 | J:163175 Rice DP, Connor EC, Veltmaat JM, Lana-Elola E, Veistinen L, Tanimoto Y, Bellusci S, Rice R, Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation. Hum Mol Genet. 2010 Sep 1;19(17):3457-67 |
2* | J:76140 Shibata S, Fukada K, Suzuki S, Ogawa T, Yamashita Y, In situ hybridization and immunohistochemistry of bone sialoprotein and secreted phosphoprotein 1 (osteopontin) in the developing mouse mandibular condylar cartilage compared with limb bud cartilage. J Anat. 2002 Mar;200(Pt 3):309-20 |
1* | J:306243 Shur I, Socher R, Benayahu D, In vivo association of CReMM/CHD9 with promoters in osteogenic cells. J Cell Physiol. 2006 May;207(2):374-8 |
1 | J:333326 Suh J, Kim NK, Shim W, Lee SH, Kim HJ, Moon E, Sesaki H, Jang JH, Kim JE, Lee YS, Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab. 2023 Feb 7;35(2):345-360.e7 |
1* | J:289500 Veistinen L, Takatalo M, Tanimoto Y, Kesper DA, Vortkamp A, Rice DP, Loss-of-Function of Gli3 in Mice Causes Abnormal Frontal Bone Morphology and Premature Synostosis of the Interfrontal Suture. Front Physiol. 2012;3:121 |
1 | J:185130 Wei J, Shi Y, Zheng L, Zhou B, Inose H, Wang J, Guo XE, Grosschedl R, Karsenty G, miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. J Cell Biol. 2012 May 14;197(4):509-21 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1 | J:202210 Zhang X, Ting K, Pathmanathan D, Ko T, Chen W, Chen F, Lee H, James AW, Siu RK, Shen J, Culiat CT, Soo C, Calvarial cleidocraniodysplasia-like defects with ENU-induced Nell-1 deficiency. J Craniofac Surg. 2012 Jan;23(1):61-6 |
Icam1 intercellular adhesion molecule 1 (Synonyms: CD54, Icam-1, Ly-47, MALA-2, MGC:6195) | |
Results | Reference |
1* | J:36690 Buck CA, Edelman JM, Buck CE, Kennedy G, Baldwin HS, Expression patterns of adhesion receptors in the developing mouse lung: functional implications. Cell Adhes Commun. 1996 Aug;4(2):69-87 |
1 | J:87395 Eberl G, Marmon S, Sunshine MJ, Rennert PD, Choi Y, Littman DR, An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat Immunol. 2004 Jan;5(1):64-73 |
1* | J:67917 Honda K, Nakano H, Yoshida H, Nishikawa S, Rennert P, Ikuta K, Tamechika M, Yamaguchi K, Fukumoto T, Chiba T, Nishikawa SI, Molecular basis for hematopoietic/mesenchymal interaction during initiation of peyer's patch organogenesis. J Exp Med. 2001 Mar 5;193(5):621-30 |
1 | J:361142 Ke X, van Soldt B, Vlahos L, Zhou Y, Qian J, George J, Capdevila C, Glass I, Yan K, Califano A, Cardoso WV, Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate. Dev Cell. 2024 Dec 9; |
1 | J:137812 Vondenhoff MF, Desanti GE, Cupedo T, Bertrand JY, Cumano A, Kraal G, Mebius RE, Golub R, Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner. J Leukoc Biol. 2008 Jul;84(1):152-61 |
1 | J:150308 Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009 May 1;182(9):5439-45 |
Icam2 intercellular adhesion molecule 2 (Synonyms: CD102, Icam-2) | |
Results | Reference |
1 | J:297253 Vila Ellis L, Cain MP, Hutchison V, Flodby P, Crandall ED, Borok Z, Zhou B, Ostrin EJ, Wythe JD, Chen J, Epithelial Vegfa Specifies a Distinct Endothelial Population in the Mouse Lung. Dev Cell. 2020 Mar 9;52(5):617-630.e6 |
Id1 inhibitor of DNA binding 1, HLH protein (Synonyms: bHLHb24, D2Wsu140e, Idb1) | |
Results | Reference |
3 | J:170418 Du Y, Yip HK, The expression and roles of inhibitor of DNA binding helix-loop-helix proteins in the developing and adult mouse retina. Neuroscience. 2011 Feb 23;175:367-79 |
2* | J:3027 Duncan M, DiCicco-Bloom EM, Xiang X, Benezra R, Chada K, The gene for the helix-loop-helix protein, Id, is specifically expressed in neural precursors. Dev Biol. 1992 Nov;154(1):1-10 |
1* | J:140317 Inagaki M, Komatsu Y, Scott G, Yamada G, Ray M, Ninomiya-Tsuji J, Mishina Y, Generation of a conditional mutant allele for Tab1 in mouse. Genesis. 2008 Aug;46(8):431-9 |
1* | J:36589 Jen Y, Manova K, Benezra R, Expression patterns of Id1, Id2, and Id3 are highly related but distinct from that of Id4 during mouse embryogenesis. Dev Dyn. 1996 Nov;207(3):235-52 |
1* | J:331303 Kantzer CG, Yang W, Grommisch D, Patikl KV, Mak KH, Shirokova V, Genander M, ID1 and CEBPA coordinate epidermal progenitor cell differentiation. Development. 2022 Nov;149(22) |
1 | J:308704 Kiyokawa H, Yamaoka A, Matsuoka C, Tokuhara T, Abe T, Morimoto M, Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfbeta-Id2 axis, for tissue regeneration. Dev Cell. 2021 Jul 12;56(13):1917-1929.e9 |
1 | J:122971 Moskowitz IP, Kim JB, Moore ML, Wolf CM, Peterson MA, Shendure J, Nobrega MA, Yokota Y, Berul C, Izumo S, Seidman JG, Seidman CE, A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development. Cell. 2007 Jun 29;129(7):1365-76 |
1 | J:300278 Omiya H, Yamaguchi S, Watanabe T, Kuniya T, Harada Y, Kawaguchi D, Gotoh Y, BMP signaling suppresses Gemc1 expression and ependymal differentiation of mouse telencephalic progenitors. Sci Rep. 2021 Jan 12;11(1):613 |
1 | J:100235 Rice R, Thesleff I, Rice DP, Regulation of Twist, Snail, and Id1 is conserved between the developing murine palate and tooth. Dev Dyn. 2005 Sep;234(1):28-35 |
1* | J:17442 Riechmann V, van Cruchten I, Sablitzky F, The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3. Nucleic Acids Res. 1994 Mar 11;22(5):749-55 |
1* | J:3324 Wang Y, Benezra R, Sassoon DA, Id expression during mouse development: a role in morphogenesis. Dev Dyn. 1992 Jul;194(3):222-30 |
1* | J:25647 Zhu W, Dahmen J, Bulfone A, Rigolet M, Hernandez MC, Kuo WL, Puelles L, Rubenstein JL, Israel MA, Id gene expression during development and molecular cloning of the human Id-1 gene. Brain Res Mol Brain Res. 1995 Jun;30(2):312-26 |
Id2 inhibitor of DNA binding 2 (Synonyms: bHLHb26, C78922, Idb2, inhibitor of differentiation 2) | |
Results | Reference |
1 | J:127387 Armentano M, Chou SJ, Tomassy GS, Leingartner A, O'Leary DD, Studer M, COUP-TFI regulates the balance of cortical patterning between frontal/motor and sensory areas. Nat Neurosci. 2007 Oct;10(10):1277-86 |
1* | J:155785 Brinkmeier ML, Davis SW, Carninci P, MacDonald JW, Kawai J, Ghosh D, Hayashizaki Y, Lyons RH, Camper SA, Discovery of transcriptional regulators and signaling pathways in the developing pituitary gland by bioinformatic and genomic approaches. Genomics. 2009 May;93(5):449-60 |
3 | J:170418 Du Y, Yip HK, The expression and roles of inhibitor of DNA binding helix-loop-helix proteins in the developing and adult mouse retina. Neuroscience. 2011 Feb 23;175:367-79 |
1* | J:184357 Dye CA, El Shawa H, Huffman KJ, A lifespan analysis of intraneocortical connections and gene expression in the mouse I. Cereb Cortex. 2011 Jun;21(6):1311-30 |
1* | J:36589 Jen Y, Manova K, Benezra R, Expression patterns of Id1, Id2, and Id3 are highly related but distinct from that of Id4 during mouse embryogenesis. Dev Dyn. 1996 Nov;207(3):235-52 |
1 | J:308704 Kiyokawa H, Yamaoka A, Matsuoka C, Tokuhara T, Abe T, Morimoto M, Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfbeta-Id2 axis, for tissue regeneration. Dev Cell. 2021 Jul 12;56(13):1917-1929.e9 |
1 | J:237343 Laresgoiti U, Nikolic MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL, Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016 Oct 15;143(20):3686-3699 |
1 | J:101702 Li B, Nair M, Mackay DR, Bilanchone V, Hu M, Fallahi M, Song H, Dai Q, Cohen PE, Dai X, Ovol1 regulates meiotic pachytene progression during spermatogenesis by repressing Id2 expression. Development. 2005 Mar;132(6):1463-73 |
1 | J:317604 Liu F, Lu MM, Patel NN, Schillinger KJ, Wang T, Patel VV, GATA-Binding Factor 6 Contributes to Atrioventricular Node Development and Function. Circ Cardiovasc Genet. 2015 Apr;8(2):284-93 |
1 | J:122971 Moskowitz IP, Kim JB, Moore ML, Wolf CM, Peterson MA, Shendure J, Nobrega MA, Yokota Y, Berul C, Izumo S, Seidman JG, Seidman CE, A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development. Cell. 2007 Jun 29;129(7):1365-76 |
1 | J:107381 Nadra K, Anghel SI, Joye E, Tan NS, Basu-Modak S, Trono D, Wahli W, Desvergne B, Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta. Mol Cell Biol. 2006 Apr;26(8):3266-81 |
1 | J:154450 Rawlins EL, Clark CP, Xue Y, Hogan BL, The Id2+ distal tip lung epithelium contains individual multipotent embryonic progenitor cells. Development. 2009 Nov;136(22):3741-5 |
1* | J:17442 Riechmann V, van Cruchten I, Sablitzky F, The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3. Nucleic Acids Res. 1994 Mar 11;22(5):749-55 |
1 | J:361958 Straube P, Beckers A, Jany UWH, Bergmann F, Ludtke TH, Rudat C, Trowe MO, Peters I, Klopf MG, Mamo TM, Kispert A, Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter. Development. 2025 Feb 1;152(3) |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
1 | J:159315 Xie Z, Ma X, Ji W, Zhou G, Lu Y, Xiang Z, Wang YX, Zhang L, Hu Y, Ding YQ, Zhang WJ, Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6510-5 |
1* | J:149788 Yang L, Ma X, Lyone A, Zou J, Blackburn ML, Pan J, Yang D, Matsushita H, Mei B, Zielinska-Kwiatkowska A, Chansky HA, Proper expression of helix-loop-helix protein Id2 is important to chondrogenic differentiation of ATDC5 cells. Biochem J. 2009 May 1;419(3):635-43 |
1* | J:25647 Zhu W, Dahmen J, Bulfone A, Rigolet M, Hernandez MC, Kuo WL, Puelles L, Rubenstein JL, Israel MA, Id gene expression during development and molecular cloning of the human Id-1 gene. Brain Res Mol Brain Res. 1995 Jun;30(2):312-26 |
Id3 inhibitor of DNA binding 3 (Synonyms: bHLHb25, HLH462, Idb3) | |
Results | Reference |
1* | J:155785 Brinkmeier ML, Davis SW, Carninci P, MacDonald JW, Kawai J, Ghosh D, Hayashizaki Y, Lyons RH, Camper SA, Discovery of transcriptional regulators and signaling pathways in the developing pituitary gland by bioinformatic and genomic approaches. Genomics. 2009 May;93(5):449-60 |
1 | J:196361 Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnani MG, Messina G, Cossu G, Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory. Dev Cell. 2013 Mar 25;24(6):586-99 |
3 | J:170418 Du Y, Yip HK, The expression and roles of inhibitor of DNA binding helix-loop-helix proteins in the developing and adult mouse retina. Neuroscience. 2011 Feb 23;175:367-79 |
1* | J:36589 Jen Y, Manova K, Benezra R, Expression patterns of Id1, Id2, and Id3 are highly related but distinct from that of Id4 during mouse embryogenesis. Dev Dyn. 1996 Nov;207(3):235-52 |
1 | J:308704 Kiyokawa H, Yamaoka A, Matsuoka C, Tokuhara T, Abe T, Morimoto M, Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfbeta-Id2 axis, for tissue regeneration. Dev Cell. 2021 Jul 12;56(13):1917-1929.e9 |
1 | J:348857 Li Z, Liu G, Yang L, Sun M, Zhang Z, Xu Z, Gao Y, Jiang X, Su Z, Li X, Yang Z, BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period. Protein Cell. 2024 Jan 3;15(1):21-35 |
1 | J:122971 Moskowitz IP, Kim JB, Moore ML, Wolf CM, Peterson MA, Shendure J, Nobrega MA, Yokota Y, Berul C, Izumo S, Seidman JG, Seidman CE, A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development. Cell. 2007 Jun 29;129(7):1365-76 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
1* | J:17442 Riechmann V, van Cruchten I, Sablitzky F, The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3. Nucleic Acids Res. 1994 Mar 11;22(5):749-55 |
Id4 inhibitor of DNA binding 4 (Synonyms: bHLHb27, Id4, Idb4) | |
Results | Reference |
3 | J:170418 Du Y, Yip HK, The expression and roles of inhibitor of DNA binding helix-loop-helix proteins in the developing and adult mouse retina. Neuroscience. 2011 Feb 23;175:367-79 |
1* | J:36589 Jen Y, Manova K, Benezra R, Expression patterns of Id1, Id2, and Id3 are highly related but distinct from that of Id4 during mouse embryogenesis. Dev Dyn. 1996 Nov;207(3):235-52 |
1* | J:37519 Jen Y, Manova K, Benezra R, Each member of the Id gene family exhibits a unique expression pattern in mouse gastrulation and neurogenesis. Dev Dyn. 1997 Jan;208(1):92-106 |
1 | J:122971 Moskowitz IP, Kim JB, Moore ML, Wolf CM, Peterson MA, Shendure J, Nobrega MA, Yokota Y, Berul C, Izumo S, Seidman JG, Seidman CE, A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development. Cell. 2007 Jun 29;129(7):1365-76 |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
1 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1* | J:17442 Riechmann V, van Cruchten I, Sablitzky F, The expression pattern of Id4, a novel dominant negative helix-loop-helix protein, is distinct from Id1, Id2 and Id3. Nucleic Acids Res. 1994 Mar 11;22(5):749-55 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:267715 Wiwatpanit T, Lorenzen SM, Cantu JA, Foo CZ, Hogan AK, Marquez F, Clancy JC, Schipma MJ, Cheatham MA, Duggan A, Garcia-Anoveros J, Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1. Nature. 2018 Nov;563(7733):691-695 |
Idh3g isocitrate dehydrogenase 3 (NAD+), gamma | |
Results | Reference |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
Ids iduronate 2-sulfatase | |
Results | Reference |
1* | J:160587 Ratzka A, Mundlos S, Vortkamp A, Expression patterns of sulfatase genes in the developing mouse embryo. Dev Dyn. 2010 Jun;239(6):1779-88 |
Ier2 immediate early response 2 (Synonyms: ch1, pip92) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Ifi202b interferon activated gene 202B (Synonyms: p202) | |
Results | Reference |
1 | J:163484 Lin MH, Chang KW, Lin SC, Miner JH, Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling. Dev Biol. 2010 Aug 15;344(2):707-19 |
Ifi204 interferon activated gene 204 (Synonyms: p204) | |
Results | Reference |
1 | J:64032 Liu Cj, Wang H, Zhao Z, Yu S, Lu YB, Meyer J, Chatterjee G, Deschamps S, Roe BA, Lengyel P, MyoD-dependent induction during myoblast differentiation of p204, a protein also inducible by interferon. Mol Cell Biol. 2000 Sep;20(18):7024-36 |
Ifit1 interferon-induced protein with tetratricopeptide repeats 1 (Synonyms: Ifi56, ISG56) | |
Results | Reference |
1 | J:288683 Gacem N, Kavo A, Zerad L, Richard L, Mathis S, Kapur RP, Parisot M, Amiel J, Dufour S, de la Grange P, Pingault V, Vallat JM, Bondurand N, ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. Nat Commun. 2020 Jan 10;11(1):198 |
1 | J:275825 Norman TA Jr, Gower AC, Chen F, Fine A, Transcriptional landscape of pulmonary lymphatic endothelial cells during fetal gestation. PLoS One. 2019;14(5):e0216795 |
Ifit2 interferon-induced protein with tetratricopeptide repeats 2 (Synonyms: Ifi54) | |
Results | Reference |
1 | J:288683 Gacem N, Kavo A, Zerad L, Richard L, Mathis S, Kapur RP, Parisot M, Amiel J, Dufour S, de la Grange P, Pingault V, Vallat JM, Bondurand N, ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. Nat Commun. 2020 Jan 10;11(1):198 |
Ifitm5 interferon induced transmembrane protein 5 (Synonyms: 1110003J06Rik, Bril, fragilis4, Hrmp1) | |
Results | Reference |
1 | J:215966 Hanagata N, Li X, Morita H, Takemura T, Li J, Minowa T, Characterization of the osteoblast-specific transmembrane protein IFITM5 and analysis of IFITM5-deficient mice. J Bone Miner Metab. 2011 May;29(3):279-90 |
1* | J:152591 Moffatt P, Gaumond MH, Salois P, Sellin K, Bessette MC, Godin E, de Oliveira PT, Atkins GJ, Nanci A, Thomas G, Bril: a novel bone-specific modulator of mineralization. J Bone Miner Res. 2008 Sep;23(9):1497-508 |
1 | J:360379 Wang Z, Wang K, Yu Y, Fu J, Zhang S, Li M, Yang J, Zhang X, Liu X, Lv F, Ma L, Cai H, Tian W, Liao L, Identification of human cranio-maxillofacial skeletal stem cells for mandibular development. Sci Adv. 2025 Jan 3;11(1):eado7852 |
Ifng interferon gamma (Synonyms: Ifg, IFN-gamma) | |
Results | Reference |
1 | J:21326 Deman J, Humblet C, Martin MT, Boniver J, Defresne MP, Analysis by in situ hybridization of cytokine mRNA expression in the murine developing thymus. Int Immunol. 1994 Oct;6(10):1613-9 |
1* | J:35158 Deman J, Van Meurs M, Claassen E, Humblet C, Boniver J, Defresne MP, In vivo expression of interleukin-1 beta (IL-1 beta), IL-2, IL-4, IL-6, tumour necrosis factor-alpha and interferon-gamma in the fetal murine thymus. Immunology. 1996 Sep;89(1):152-7 |
1* | J:44503 Montgomery RA, Dallman MJ, Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny. Cytokine. 1997 Oct;9(10):717-26 |
1* | J:55762 Montgomery RA, Dallman MJ, Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J Immunol. 1991 Jul 15;147(2):554-60 |
Ift20 intraflagellar transport 20 (Synonyms: 0610009H04Rik) | |
Results | Reference |
1 | J:343556 Kretschmer V, Schneider S, Matthiessen PA, Reichert D, Hotaling N, Glassser G, Lieberwirth I, Bharti K, De Cegli R, Conte I, Nandrot EF, May-Simera HL, Deletion of IFT20 exclusively in the RPE ablates primary cilia and leads to retinal degeneration. PLoS Biol. 2023 Dec;21(12):e3002402 |
Ift25 intraflagellar transport 25 (Synonyms: 2900042B11Rik, Hspb11) | |
Results | Reference |
1* | J:299510 Wang JJ, Ge W, Zhai QY, Liu JC, Sun XW, Liu WX, Li L, Lei CZ, Dyce PW, De Felici M, Shen W, Single-cell transcriptome landscape of ovarian cells during primordial follicle assembly in mice. PLoS Biol. 2020 Dec;18(12):e3001025 |
Ift46 intraflagellar transport 46 (Synonyms: 1500035H01Rik, IFT46) | |
Results | Reference |
1* | J:126763 Gouttenoire J, Valcourt U, Bougault C, Aubert-Foucher E, Arnaud E, Giraud L, Mallein-Gerin F, Knockdown of the intraflagellar transport protein IFT46 stimulates selective gene expression in mouse chondrocytes and affects early development in zebrafish. J Biol Chem. 2007 Oct 19;282(42):30960-73 |
Ift88 intraflagellar transport 88 (Synonyms: fxo, IFT88, Oak Ridge polycystic kidneys, orpk, polaris, Tg737, Tg737Rpw, TgN737Rpw, Ttc10) | |
Results | Reference |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:146634 Ohazama A, Haycraft CJ, Seppala M, Blackburn J, Ghafoor S, Cobourne M, Martinelli DC, Fan CM, Peterkova R, Lesot H, Yoder BK, Sharpe PT, Primary cilia regulate Shh activity in the control of molar tooth number. Development. 2009 Mar;136(6):897-903 |
1 | J:317613 Patnaik SR, Kretschmer V, Brucker L, Schneider S, Volz AK, Oancea-Castillo LDR, May-Simera HL, Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation. Cell Mol Life Sci. 2019 Feb;76(4):757-775 |
1 | J:125042 Pierreux CE, Poll AV, Kemp CR, Clotman F, Maestro MA, Cordi S, Ferrer J, Leyns L, Rousseau GG, Lemaigre FP, The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. Gastroenterology. 2006 Feb;130(2):532-41 |
1* | J:229895 Sugiyama Y, Shelley EJ, Yoder BK, Kozmik Z, May-Simera HL, Beales PL, Lovicu FJ, McAvoy JW, Non-essential role for cilia in coordinating precise alignment of lens fibres. Mech Dev. 2016 Feb;139:10-7 |
Ift122 intraflagellar transport 122 (Synonyms: C86139, sopb, Wdr10) | |
Results | Reference |
1 | J:143544 Cortellino S, Wang C, Wang B, Bassi MR, Caretti E, Champeval D, Calmont A, Jarnik M, Burch J, Zaret KS, Larue L, Bellacosa A, Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4. Dev Biol. 2009 Jan 1;325(1):225-37 |
Ift140 intraflagellar transport 140 (Synonyms: mKIAA0590, Tce5, Wdtc2) | |
Results | Reference |
1* | J:320816 Zhang C, Zhang S, Sun Y, Expression of IFT140 During Bone Development. J Histochem Cytochem. 2019 Oct;67(10):723-734 |
Igdcc3 immunoglobulin superfamily, DCC subclass, member 3 (Synonyms: 2810401C09Rik, Punc, WI-14920) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
2* | J:70796 Yang W, Li C, Mansour SL, Impaired motor coordination in mice that lack punc. Mol Cell Biol. 2001 Sep;21(17):6031-43 |
Igdcc4 immunoglobulin superfamily, DCC subclass, member 4 (Synonyms: 9330155G14Rik, mKIAA1628, Nope, WI-16786, WI-18508) | |
Results | Reference |
2* | J:187541 Schievenbusch S, Sauer E, Curth HM, Schulte S, Demir M, Toex U, Goeser T, Nierhoff D, Neighbor of punc e 11: expression pattern of the new hepatic stem/progenitor cell marker during murine liver development. Stem Cells Dev. 2012 Sep 20;21(14):2656-66 |
Igf1 insulin-like growth factor 1 (Synonyms: C730016P09Rik, Igf-1, Igf-I) | |
Results | Reference |
1* | J:120667 Bouzin C, Clotman F, Renauld JC, Lemaigre FP, Rousseau GG, The onecut transcription factor hepatocyte nuclear factor-6 controls B lymphopoiesis in fetal liver. J Immunol. 2003 Aug 1;171(3):1297-303 |
1 | J:106102 Carter AM, Nygard K, Mazzuca DM, Han VK, The expression of insulin-like growth factor and insulin-like growth factor binding protein mRNAs in mouse placenta. Placenta. 2006 Feb-Mar;27(2-3):278-90 |
1* | J:98507 Caton J, Bringas P Jr, Zeichner-David M, IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes. Arch Oral Biol. 2005 Feb;50(2):123-9 |
1 | J:267108 Cho E, Mysliwiec MR, Carlson CD, Ansari A, Schwartz RJ, Lee Y, Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development. J Biol Chem. 2018 Jul 27;293(30):11659-11673 |
1 | J:346123 Darrigrand JF, Salowka A, Torres-Cano A, Tapia-Rojo R, Zhu T, Garcia-Manyes S, Spagnoli FM, Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner. Dev Cell. 2024 Feb 5;59(3):326-338.e5 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:95138 Inanlou MR, Kablar B, Abnormal development of the intercostal muscles and the rib cage in Myf5-/- embryos leads to pulmonary hypoplasia. Dev Dyn. 2005 Jan;232(1):43-54 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:326523 Kheirollahi V, Khadim A, Kiliaris G, Korfei M, Barroso MM, Alexopoulos I, Vazquez-Armendariz AI, Wygrecka M, Ruppert C, Guenther A, Seeger W, Herold S, El Agha E, Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis. Cells. 2022 Jun 20;11(12) |
1 | J:241923 Lopez IP, Pineiro-Hermida S, Pais RS, Torrens R, Hoeflich A, Pichel JG, Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation. PLoS One. 2016;11(11):e0166388 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1* | J:126194 Nagata K, Masumoto K, Uesugi T, Yamamoto S, Yoshizaki K, Fukumoto S, Nonaka K, Taguchi T, Effect of insulin-like-growth factor and its receptors regarding lung development in fetal mice. Pediatr Surg Int. 2007 Oct;23(10):953-9 |
2* | J:178908 Okano T, Xuan S, Kelley MW, Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea. J Neurosci. 2011 Dec 7;31(49):18104-18 |
1 | J:161760 Provost PR, Simard M, Tremblay Y, A link between lung androgen metabolism and the emergence of mature epithelial type II cells. Am J Respir Crit Care Med. 2004 Aug 1;170(3):296-305 |
1* | J:148934 Salehi Z, Mashayekhi F, Naji M, Pandamooz S, Insulin-like growth factor-1 and insulin-like growth factor binding proteins in cerebrospinal fluid during the development of mouse embryos. J Clin Neurosci. 2009 Jul;16(7):950-3 |
1 | J:187514 Shibata S, Fukuoka H, Sato R, Abe T, Suzuki Y, An in situ hybridization study of the insulin-like growth factor system in developing condylar cartilage of the fetal mouse mandible. Eur J Histochem. 2012 May 23;56(2):e23 |
1* | J:272586 Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, Yamamoto T, Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019 Feb 15;146(4):dev168146 |
2 | J:222261 Tan KS, Inoue T, Kulkeaw K, Tanaka Y, Lai MI, Sugiyama D, Localized SCF and IGF-1 secretion enhances erythropoiesis in the spleen of murine embryos. Biol Open. 2015;4(5):596-607 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
1 | J:137214 Villalpando I, Lira E, Medina G, Garcia-Garcia E, Echeverria O, Insulin-like growth factor 1 is expressed in mouse developing testis and regulates somatic cell proliferation. Exp Biol Med (Maywood). 2008 Apr;233(4):419-26 |
2* | J:86408 Villalpando I, Lopez-Olmos V, Insulin-like growth factor I (IGF-I) regulates endocrine activity of the embryonic testis in the mouse. J Steroid Biochem Mol Biol. 2003 Aug;86(2):151-8 |
1 | J:113656 Wang Y, Nishida S, Sakata T, Elalieh HZ, Chang W, Halloran BP, Doty SB, Bikle DD, Insulin-like growth factor-I is essential for embryonic bone development. Endocrinology. 2006 Oct;147(10):4753-61 |
1 | J:321563 Yan Y, Qin Q, Wu L, Jing X, Deng S, She Q, Insulin-like growth factor 1 receptor signaling regulates embryonic epicardial cell proliferation through focal adhesion kinase pathway. Acta Biochim Biophys Sin (Shanghai). 2018 Oct 1;50(10):976-983 |
Igf1r insulin-like growth factor I receptor (Synonyms: A330103N21Rik, CD221, hyft, IGF-1R, line 186) | |
Results | Reference |
1* | J:98507 Caton J, Bringas P Jr, Zeichner-David M, IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes. Arch Oral Biol. 2005 Feb;50(2):123-9 |
2 | J:346123 Darrigrand JF, Salowka A, Torres-Cano A, Tapia-Rojo R, Zhu T, Garcia-Manyes S, Spagnoli FM, Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner. Dev Cell. 2024 Feb 5;59(3):326-338.e5 |
1 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
1 | J:326523 Kheirollahi V, Khadim A, Kiliaris G, Korfei M, Barroso MM, Alexopoulos I, Vazquez-Armendariz AI, Wygrecka M, Ruppert C, Guenther A, Seeger W, Herold S, El Agha E, Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis. Cells. 2022 Jun 20;11(12) |
1 | J:174742 Lehtinen MK, Zappaterra MW, Chen X, Yang YJ, Hill AD, Lun M, Maynard T, Gonzalez D, Kim S, Ye P, D'Ercole AJ, Wong ET, LaMantia AS, Walsh CA, The cerebrospinal fluid provides a proliferative niche for neural progenitor cells. Neuron. 2011 Mar 10;69(5):893-905 |
1 | J:241923 Lopez IP, Pineiro-Hermida S, Pais RS, Torrens R, Hoeflich A, Pichel JG, Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation. PLoS One. 2016;11(11):e0166388 |
1* | J:126194 Nagata K, Masumoto K, Uesugi T, Yamamoto S, Yoshizaki K, Fukumoto S, Nonaka K, Taguchi T, Effect of insulin-like-growth factor and its receptors regarding lung development in fetal mice. Pediatr Surg Int. 2007 Oct;23(10):953-9 |
2* | J:178908 Okano T, Xuan S, Kelley MW, Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea. J Neurosci. 2011 Dec 7;31(49):18104-18 |
1 | J:329315 Sheldon C, Farley A, Ma Q, Pu WT, Lin Z, Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development. Cells. 2022 Sep 10;11(18) |
1 | J:187514 Shibata S, Fukuoka H, Sato R, Abe T, Suzuki Y, An in situ hybridization study of the insulin-like growth factor system in developing condylar cartilage of the fetal mouse mandible. Eur J Histochem. 2012 May 23;56(2):e23 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
1 | J:137214 Villalpando I, Lira E, Medina G, Garcia-Garcia E, Echeverria O, Insulin-like growth factor 1 is expressed in mouse developing testis and regulates somatic cell proliferation. Exp Biol Med (Maywood). 2008 Apr;233(4):419-26 |
1 | J:113656 Wang Y, Nishida S, Sakata T, Elalieh HZ, Chang W, Halloran BP, Doty SB, Bikle DD, Insulin-like growth factor-I is essential for embryonic bone development. Endocrinology. 2006 Oct;147(10):4753-61 |
1 | J:321563 Yan Y, Qin Q, Wu L, Jing X, Deng S, She Q, Insulin-like growth factor 1 receptor signaling regulates embryonic epicardial cell proliferation through focal adhesion kinase pathway. Acta Biochim Biophys Sin (Shanghai). 2018 Oct 1;50(10):976-983 |
Igf2 insulin-like growth factor 2 (Synonyms: Igf-2, Igf-II, M6pr, Mpr, Peg2) | |
Results | Reference |
1* | J:39320 Beechey CV, Ball ST, Townsend KM, Jones J, The mouse chromosome 7 distal imprinting domain maps to G-bands F4/F5. Mamm Genome. 1997 Apr;8(4):236-40 |
1* | J:120667 Bouzin C, Clotman F, Renauld JC, Lemaigre FP, Rousseau GG, The onecut transcription factor hepatocyte nuclear factor-6 controls B lymphopoiesis in fetal liver. J Immunol. 2003 Aug 1;171(3):1297-303 |
1 | J:106102 Carter AM, Nygard K, Mazzuca DM, Han VK, The expression of insulin-like growth factor and insulin-like growth factor binding protein mRNAs in mouse placenta. Placenta. 2006 Feb-Mar;27(2-3):278-90 |
1* | J:98507 Caton J, Bringas P Jr, Zeichner-David M, IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes. Arch Oral Biol. 2005 Feb;50(2):123-9 |
1* | J:159378 Chou S, Lodish HF, Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7799-804 |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
2 | J:167738 Hardouin SN, Guo R, Romeo PH, Nagy A, Aubin JE, Impaired mesenchymal stem cell differentiation and osteoclastogenesis in mice deficient for Igf2-P2 transcripts. Development. 2011 Jan;138(2):203-13 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:218430 Kamimura S, Hatanaka Y, Hirasawa R, Matsumoto K, Oikawa M, Lee J, Matoba S, Mizutani E, Ogonuki N, Inoue K, Kohda T, Ishino F, Ogura A, Establishment of paternal genomic imprinting in mouse prospermatogonia analyzed by nuclear transfer. Biol Reprod. 2014 Nov;91(5):120 |
1 | J:326523 Kheirollahi V, Khadim A, Kiliaris G, Korfei M, Barroso MM, Alexopoulos I, Vazquez-Armendariz AI, Wygrecka M, Ruppert C, Guenther A, Seeger W, Herold S, El Agha E, Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis. Cells. 2022 Jun 20;11(12) |
1 | J:307414 Liao J, Zeng TB, Pierce N, Tran DA, Singh P, Mann JR, Szabo PE, Prenatal correction of IGF2 to rescue the growth phenotypes in mouse models of Beckwith-Wiedemann and Silver-Russell syndromes. Cell Rep. 2021 Feb 9;34(6):108729 |
1 | J:241923 Lopez IP, Pineiro-Hermida S, Pais RS, Torrens R, Hoeflich A, Pichel JG, Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation. PLoS One. 2016;11(11):e0166388 |
1* | J:267655 Marjonen H, Toivonen M, Lahti L, Kaminen-Ahola N, Early prenatal alcohol exposure alters imprinted gene expression in placenta and embryo in a mouse model. PLoS One. 2018;13(5):e0197461 |
1 | J:125838 Merrick D, Ting T, Stadler LK, Smith J, A role for Insulin-like growth factor 2 in specification of the fast skeletal muscle fibre. BMC Dev Biol. 2007;7:65 |
1* | J:126194 Nagata K, Masumoto K, Uesugi T, Yamamoto S, Yoshizaki K, Fukumoto S, Nonaka K, Taguchi T, Effect of insulin-like-growth factor and its receptors regarding lung development in fetal mice. Pediatr Surg Int. 2007 Oct;23(10):953-9 |
2* | J:178908 Okano T, Xuan S, Kelley MW, Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea. J Neurosci. 2011 Dec 7;31(49):18104-18 |
1 | J:305574 Shen H, Gan P, Wang K, Darehzereshki A, Wang K, Kumar SR, Lien CL, Patterson M, Tao G, Sucov HM, Mononuclear diploid cardiomyocytes support neonatal mouse heart regeneration in response to paracrine IGF2 signaling. Elife. 2020 Mar 13;9:e53071 |
1 | J:187514 Shibata S, Fukuoka H, Sato R, Abe T, Suzuki Y, An in situ hybridization study of the insulin-like growth factor system in developing condylar cartilage of the fetal mouse mandible. Eur J Histochem. 2012 May 23;56(2):e23 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
2* | J:272586 Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, Yamamoto T, Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019 Feb 15;146(4):dev168146 |
1 | J:30428 Szabo PE, Mann JR, Allele-specific expression and total expression levels of imprinted genes during early mouse development: implications for imprinting mechanisms. Genes Dev. 1995 Dec 15;9(24):3097-108 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
1 | J:256746 Wang X, Shan X, Gregory-Evans CY, A mouse model of aniridia reveals the in vivo downstream targets of Pax6 driving iris and ciliary body development in the eye. Biochim Biophys Acta. 2017 Jan;1863(1):60-67 |
1* | J:21229 Ward A, Bates P, Fisher R, Richardson L, Graham CF, Disproportionate growth in mice with Igf-2 transgenes. Proc Natl Acad Sci U S A. 1994 Oct 25;91(22):10365-9 |
1 | J:321563 Yan Y, Qin Q, Wu L, Jing X, Deng S, She Q, Insulin-like growth factor 1 receptor signaling regulates embryonic epicardial cell proliferation through focal adhesion kinase pathway. Acta Biochim Biophys Sin (Shanghai). 2018 Oct 1;50(10):976-983 |
Igf2bp1 insulin-like growth factor 2 mRNA binding protein 1 (Synonyms: Crdbp, CRD-BP, D030026A21Rik, D11Moh40e, D11Moh45, IMP-1, IMP1, Zbp1) | |
Results | Reference |
1* | J:100054 Hammer NA, Hansen TO, Byskov AG, Rajpert-De Meyts E, Grondahl ML, Bredkjaer HE, Wewer UM, Christiansen J, Nielsen FC, Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer. Reproduction. 2005 Aug;130(2):203-12 |
1* | J:104317 Islam S, Montgomery RK, Fialkovich JJ, Grand RJ, Developmental and regional expression and localization of mRNAs encoding proteins involved in RNA translocation. J Histochem Cytochem. 2005 Dec;53(12):1501-9 |
1 | J:207231 Nishino J, Kim S, Zhu Y, Zhu H, Morrison SJ, A network of heterochronic genes including Imp1 regulates temporal changes in stem cell properties. Elife. 2013;2:e00924 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Igf2bp2 insulin-like growth factor 2 mRNA binding protein 2 (Synonyms: C330012H03Rik, IMP-2, IMP2) | |
Results | Reference |
1* | J:100054 Hammer NA, Hansen TO, Byskov AG, Rajpert-De Meyts E, Grondahl ML, Bredkjaer HE, Wewer UM, Christiansen J, Nielsen FC, Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer. Reproduction. 2005 Aug;130(2):203-12 |
Igf2bp3 insulin-like growth factor 2 mRNA binding protein 3 (Synonyms: 2610101N11Rik, IMP3, Koc13) | |
Results | Reference |
1* | J:100054 Hammer NA, Hansen TO, Byskov AG, Rajpert-De Meyts E, Grondahl ML, Bredkjaer HE, Wewer UM, Christiansen J, Nielsen FC, Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer. Reproduction. 2005 Aug;130(2):203-12 |
Igf2r insulin-like growth factor 2 receptor (Synonyms: CD222, CI-MPR, IGF-II/CI-MPR, M6P/IGF2R, mannose-6-phosphate receptor, cation independent, Mpr300) | |
Results | Reference |
1* | J:98507 Caton J, Bringas P Jr, Zeichner-David M, IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes. Arch Oral Biol. 2005 Feb;50(2):123-9 |
1 | J:218430 Kamimura S, Hatanaka Y, Hirasawa R, Matsumoto K, Oikawa M, Lee J, Matoba S, Mizutani E, Ogonuki N, Inoue K, Kohda T, Ishino F, Ogura A, Establishment of paternal genomic imprinting in mouse prospermatogonia analyzed by nuclear transfer. Biol Reprod. 2014 Nov;91(5):120 |
1 | J:326523 Kheirollahi V, Khadim A, Kiliaris G, Korfei M, Barroso MM, Alexopoulos I, Vazquez-Armendariz AI, Wygrecka M, Ruppert C, Guenther A, Seeger W, Herold S, El Agha E, Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis. Cells. 2022 Jun 20;11(12) |
1 | J:241923 Lopez IP, Pineiro-Hermida S, Pais RS, Torrens R, Hoeflich A, Pichel JG, Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation. PLoS One. 2016;11(11):e0166388 |
1* | J:126194 Nagata K, Masumoto K, Uesugi T, Yamamoto S, Yoshizaki K, Fukumoto S, Nonaka K, Taguchi T, Effect of insulin-like-growth factor and its receptors regarding lung development in fetal mice. Pediatr Surg Int. 2007 Oct;23(10):953-9 |
1 | J:30428 Szabo PE, Mann JR, Allele-specific expression and total expression levels of imprinted genes during early mouse development: implications for imprinting mechanisms. Genes Dev. 1995 Dec 15;9(24):3097-108 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
1* | J:20763 Wang ZQ, Fung MR, Barlow DP, Wagner EF, Regulation of embryonic growth and lysosomal targeting by the imprinted Igf2/Mpr gene. Nature. 1994 Dec 1;372(6505):464-7 |
Igfbp1 insulin-like growth factor binding protein 1 (Synonyms: IGFBP-1) | |
Results | Reference |
1 | J:106102 Carter AM, Nygard K, Mazzuca DM, Han VK, The expression of insulin-like growth factor and insulin-like growth factor binding protein mRNAs in mouse placenta. Placenta. 2006 Feb-Mar;27(2-3):278-90 |
1* | J:98507 Caton J, Bringas P Jr, Zeichner-David M, IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes. Arch Oral Biol. 2005 Feb;50(2):123-9 |
1 | J:326523 Kheirollahi V, Khadim A, Kiliaris G, Korfei M, Barroso MM, Alexopoulos I, Vazquez-Armendariz AI, Wygrecka M, Ruppert C, Guenther A, Seeger W, Herold S, El Agha E, Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis. Cells. 2022 Jun 20;11(12) |
1 | J:241923 Lopez IP, Pineiro-Hermida S, Pais RS, Torrens R, Hoeflich A, Pichel JG, Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation. PLoS One. 2016;11(11):e0166388 |
1 | J:201076 Okano T, Kelley MW, Expression of insulin-like growth factor binding proteins during mouse cochlear development. Dev Dyn. 2013 Oct;242(10):1210-21 |
Igfbp2 insulin-like growth factor binding protein 2 (Synonyms: Igfbp-2, IGFBP-2) | |
Results | Reference |
1 | J:106102 Carter AM, Nygard K, Mazzuca DM, Han VK, The expression of insulin-like growth factor and insulin-like growth factor binding protein mRNAs in mouse placenta. Placenta. 2006 Feb-Mar;27(2-3):278-90 |
1* | J:98507 Caton J, Bringas P Jr, Zeichner-David M, IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes. Arch Oral Biol. 2005 Feb;50(2):123-9 |
1 | J:267108 Cho E, Mysliwiec MR, Carlson CD, Ansari A, Schwartz RJ, Lee Y, Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development. J Biol Chem. 2018 Jul 27;293(30):11659-11673 |
1 | J:326523 Kheirollahi V, Khadim A, Kiliaris G, Korfei M, Barroso MM, Alexopoulos I, Vazquez-Armendariz AI, Wygrecka M, Ruppert C, Guenther A, Seeger W, Herold S, El Agha E, Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis. Cells. 2022 Jun 20;11(12) |
1 | J:241923 Lopez IP, Pineiro-Hermida S, Pais RS, Torrens R, Hoeflich A, Pichel JG, Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation. PLoS One. 2016;11(11):e0166388 |
2 | J:201076 Okano T, Kelley MW, Expression of insulin-like growth factor binding proteins during mouse cochlear development. Dev Dyn. 2013 Oct;242(10):1210-21 |
1 | J:187514 Shibata S, Fukuoka H, Sato R, Abe T, Suzuki Y, An in situ hybridization study of the insulin-like growth factor system in developing condylar cartilage of the fetal mouse mandible. Eur J Histochem. 2012 May 23;56(2):e23 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Igfbp3 insulin-like growth factor binding protein 3 (Synonyms: IGFBP-3) | |
Results | Reference |
1 | J:106102 Carter AM, Nygard K, Mazzuca DM, Han VK, The expression of insulin-like growth factor and insulin-like growth factor binding protein mRNAs in mouse placenta. Placenta. 2006 Feb-Mar;27(2-3):278-90 |
1* | J:98507 Caton J, Bringas P Jr, Zeichner-David M, IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes. Arch Oral Biol. 2005 Feb;50(2):123-9 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1* | J:296375 Holmes G, Gonzalez-Reiche AS, Lu N, Zhou X, Rivera J, Kriti D, Sebra R, Williams AA, Donovan MJ, Potter SS, Pinto D, Zhang B, van Bakel H, Jabs EW, Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis. Cell Rep. 2020 Jul 7;32(1):107871 |
1 | J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132 |
1 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
1 | J:241923 Lopez IP, Pineiro-Hermida S, Pais RS, Torrens R, Hoeflich A, Pichel JG, Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation. PLoS One. 2016;11(11):e0166388 |
2 | J:201076 Okano T, Kelley MW, Expression of insulin-like growth factor binding proteins during mouse cochlear development. Dev Dyn. 2013 Oct;242(10):1210-21 |
1 | J:187514 Shibata S, Fukuoka H, Sato R, Abe T, Suzuki Y, An in situ hybridization study of the insulin-like growth factor system in developing condylar cartilage of the fetal mouse mandible. Eur J Histochem. 2012 May 23;56(2):e23 |
1* | J:310487 Xiang C, Frietze KK, Bi Y, Li Y, Dal Pozzo V, Pal S, Alexander N, Baubet V, D'Acunto V, Mason CE, Davuluri RV, Dahmane N, RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons. Mol Cell Biol. 2021 Jun 23;41(7):e0052620 |
Igfbp4 insulin-like growth factor binding protein 4 (Synonyms: Band 3A, Deb2, IGFBP-4) | |
Results | Reference |
1 | J:106102 Carter AM, Nygard K, Mazzuca DM, Han VK, The expression of insulin-like growth factor and insulin-like growth factor binding protein mRNAs in mouse placenta. Placenta. 2006 Feb-Mar;27(2-3):278-90 |
1* | J:98507 Caton J, Bringas P Jr, Zeichner-David M, IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes. Arch Oral Biol. 2005 Feb;50(2):123-9 |
1 | J:326523 Kheirollahi V, Khadim A, Kiliaris G, Korfei M, Barroso MM, Alexopoulos I, Vazquez-Armendariz AI, Wygrecka M, Ruppert C, Guenther A, Seeger W, Herold S, El Agha E, Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis. Cells. 2022 Jun 20;11(12) |
1 | J:241923 Lopez IP, Pineiro-Hermida S, Pais RS, Torrens R, Hoeflich A, Pichel JG, Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation. PLoS One. 2016;11(11):e0166388 |
2 | J:201076 Okano T, Kelley MW, Expression of insulin-like growth factor binding proteins during mouse cochlear development. Dev Dyn. 2013 Oct;242(10):1210-21 |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
1 | J:187514 Shibata S, Fukuoka H, Sato R, Abe T, Suzuki Y, An in situ hybridization study of the insulin-like growth factor system in developing condylar cartilage of the fetal mouse mandible. Eur J Histochem. 2012 May 23;56(2):e23 |
Igfbp5 insulin-like growth factor binding protein 5 (Synonyms: IGFBP-5, IGFBP-5P) | |
Results | Reference |
1 | J:106102 Carter AM, Nygard K, Mazzuca DM, Han VK, The expression of insulin-like growth factor and insulin-like growth factor binding protein mRNAs in mouse placenta. Placenta. 2006 Feb-Mar;27(2-3):278-90 |
1* | J:98507 Caton J, Bringas P Jr, Zeichner-David M, IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes. Arch Oral Biol. 2005 Feb;50(2):123-9 |
1* | J:306155 Goodyer WR, Beyersdorf BM, Paik DT, Tian L, Li G, Buikema JW, Chirikian O, Choi S, Venkatraman S, Adams EL, Tessier-Lavigne M, Wu JC, Wu SM, Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution. Circ Res. 2019 Aug 2;125(4):379-397 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:326523 Kheirollahi V, Khadim A, Kiliaris G, Korfei M, Barroso MM, Alexopoulos I, Vazquez-Armendariz AI, Wygrecka M, Ruppert C, Guenther A, Seeger W, Herold S, El Agha E, Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis. Cells. 2022 Jun 20;11(12) |
1 | J:241923 Lopez IP, Pineiro-Hermida S, Pais RS, Torrens R, Hoeflich A, Pichel JG, Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation. PLoS One. 2016;11(11):e0166388 |
1 | J:243217 Muller M, Persson AB, Krueger K, Kirschner KM, Scholz H, The Wilms tumor protein WT1 stimulates transcription of the gene encoding insulin-like growth factor binding protein 5 (IGFBP5). Gene. 2017 Jul 01;619:21-29 |
1 | J:201076 Okano T, Kelley MW, Expression of insulin-like growth factor binding proteins during mouse cochlear development. Dev Dyn. 2013 Oct;242(10):1210-21 |
1 | J:187514 Shibata S, Fukuoka H, Sato R, Abe T, Suzuki Y, An in situ hybridization study of the insulin-like growth factor system in developing condylar cartilage of the fetal mouse mandible. Eur J Histochem. 2012 May 23;56(2):e23 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Igfbp6 insulin-like growth factor binding protein 6 (Synonyms: IGFBP-6) | |
Results | Reference |
1 | J:106102 Carter AM, Nygard K, Mazzuca DM, Han VK, The expression of insulin-like growth factor and insulin-like growth factor binding protein mRNAs in mouse placenta. Placenta. 2006 Feb-Mar;27(2-3):278-90 |
1* | J:98507 Caton J, Bringas P Jr, Zeichner-David M, IGFs increase enamel formation by inducing expression of enamel mineralizing specific genes. Arch Oral Biol. 2005 Feb;50(2):123-9 |
1 | J:326523 Kheirollahi V, Khadim A, Kiliaris G, Korfei M, Barroso MM, Alexopoulos I, Vazquez-Armendariz AI, Wygrecka M, Ruppert C, Guenther A, Seeger W, Herold S, El Agha E, Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis. Cells. 2022 Jun 20;11(12) |
1 | J:241923 Lopez IP, Pineiro-Hermida S, Pais RS, Torrens R, Hoeflich A, Pichel JG, Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation. PLoS One. 2016;11(11):e0166388 |
1 | J:201076 Okano T, Kelley MW, Expression of insulin-like growth factor binding proteins during mouse cochlear development. Dev Dyn. 2013 Oct;242(10):1210-21 |
1 | J:187514 Shibata S, Fukuoka H, Sato R, Abe T, Suzuki Y, An in situ hybridization study of the insulin-like growth factor system in developing condylar cartilage of the fetal mouse mandible. Eur J Histochem. 2012 May 23;56(2):e23 |
Igfbp7 insulin-like growth factor binding protein 7 (Synonyms: AGM, Fstl2, mac25) | |
Results | Reference |
1 | J:356098 Bar O, Gelb S, Atamny K, Anzi S, Ben-Zvi A, Angiomodulin (IGFBP7) is a cerebral specific angiocrine factor, but is probably not a blood-brain barrier inducer. Fluids Barriers CNS. 2020 Apr 1;17(1):27 |
Igfbpl1 insulin-like growth factor binding protein-like 1 (Synonyms: 2810011G06Rik, 2810453O06Rik, IGFBP-like protein) | |
Results | Reference |
2* | J:117819 Gonda Y, Sakurai H, Hirata Y, Tabata H, Ajioka I, Nakajima K, Expression profiles of Insulin-like growth factor binding protein-like 1 in the developing mouse forebrain. Gene Expr Patterns. 2007 Feb;7(4):431-40 |
Igll1 immunoglobulin lambda-like polypeptide 1 (Synonyms: Igl-5, Igll, Lambda 5) | |
Results | Reference |
1* | J:51642 Sabbattini P, Georgiou A, Sinclair C, Dillon N, Analysis of mice with single and multiple copies of transgenes reveals a novel arrangement for the lambda5-VpreB1 locus control region. Mol Cell Biol. 1999 Jan;19(1):671-9 |
1 | J:20032 Schlissel MS, Morrow T, Ig heavy chain protein controls B cell development by regulating germ-line transcription and retargeting V(D)J recombination. J Immunol. 1994 Aug 15;153(4):1645-57 |
Iglon5 IgLON family member 5 (Synonyms: A230106M20Rik) | |
Results | Reference |
1* | J:312430 Fearnley S, Raja R, Cloutier JF, Spatiotemporal expression of IgLON family members in the developing mouse nervous system. Sci Rep. 2021 Oct 1;11(1):19536 |
Igsf1 immunoglobulin superfamily, member 1 | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Igsf9 immunoglobulin superfamily, member 9 (Synonyms: Dasm1, mKIAA1355, NRT1) | |
Results | Reference |
1* | J:73797 Doudney K, Murdoch JN, Braybrook C, Paternotte C, Bentley L, Copp AJ, Stanier P, Cloning and characterization of igsf9 in mouse and human: a new member of the immunoglobulin superfamily expressed in the developing nervous system. Genomics. 2002 May;79(5):663-70 |
Igsf21 immunoglobulin superfamily, member 21 (Synonyms: LOC230868, MGC:67646) | |
Results | Reference |
1 | J:309347 Botella-Lopez A, Garcia-Lopez R, Pombero A, Martinez S, Radial glia fibers translate Fgf8 morphogenetic signals to generate a thalamic nuclear complex protomap in the mantle layer. Brain Struct Funct. 2019 Mar;224(2):661-679 |
1 | J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400 |
Ihh Indian hedgehog | |
Results | Reference |
1 | J:56557 Acampora D, Merlo GR, Paleari L, Zerega B, Postiglione MP, Mantero S, Bober E, Barbieri O, Simeone A, Levi G, Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5. Development. 1999 Sep;126(17):3795-809 |
1 | J:90567 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 2004 May 1;18(9):1072-87 |
1* | J:75699 Albrecht AN, Schwabe GC, Stricker S, Boddrich A, Wanker EE, Mundlos S, The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67 |
2 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
1 | J:346119 Amano K, Okuzaki D, Kitaoka Y, Kato S, Fujiwara M, Tanaka S, Iida S, Pth1r in Neural Crest Cells Regulates Nasal Cartilage Differentiation. J Dent Res. 2024 Mar;103(3):308-317 |
1 | J:337598 Au TYK, Yip RKH, Wynn SL, Tan TY, Fu A, Geng YH, Szeto IYY, Niu B, Yip KY, Cheung MCH, Lovell-Badge R, Cheah KSE, Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog-Wnt signaling, causing campomelia. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2208623119 |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
4 | J:155396 Bellon E, Luyten FP, Tylzanowski P, delta-EF1 is a negative regulator of Ihh in the developing growth plate. J Cell Biol. 2009 Nov 30;187(5):685-99 |
1* | J:85724 Bendall AJ, Hu G, Levi G, Abate-Shen C, Dlx5 regulates chondrocyte differentiation at multiple stages. Int J Dev Biol. 2003 Jun;47(5):335-44 |
1* | J:168038 Bimonte S, De Angelis A, Quagliata L, Giusti F, Tammaro R, Dallai R, Ascenzi MG, Diez-Roux G, Franco B, Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol. 2011 Jan 15;349(2):179-91 |
1 | J:156015 Blitz E, Viukov S, Sharir A, Shwartz Y, Galloway JL, Pryce BA, Johnson RL, Tabin CJ, Schweitzer R, Zelzer E, Bone ridge patterning during musculoskeletal assembly is mediated through SCX regulation of Bmp4 at the tendon-skeleton junction. Dev Cell. 2009 Dec;17(6):861-73 |
1 | J:188176 Caparros-Martin JA, Valencia M, Reytor E, Pacheco M, Fernandez M, Perez-Aytes A, Gean E, Lapunzina P, Peters H, Goodship JA, Ruiz-Perez VL, The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia. Hum Mol Genet. 2013 Jan 1;22(1):124-39 |
2* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:232617 Chen Z, Yue SX, Zhou G, Greenfield EM, Murakami S, ERK1 and ERK2 regulate chondrocyte terminal differentiation during endochondral bone formation. J Bone Miner Res. 2015 May;30(5):765-74 |
1 | J:185430 Choi SW, Jeong DU, Kim JA, Lee B, Joeng KS, Long F, Kim DW, Indian Hedgehog signalling triggers Nkx3.2 protein degradation during chondrocyte maturation. Biochem J. 2012 May 1;443(3):789-98 |
1* | J:91052 Cobourne MT, Miletich I, Sharpe PT, Restriction of sonic hedgehog signalling during early tooth development. Development. 2004 Jun;131(12):2875-85 |
1* | J:66902 Colnot C, Sidhu SS, Balmain N, Poirier F, Uncoupling of chondrocyte death and vascular invasion in mouse galectin 3 null mutant bones. Dev Biol. 2001 Jan 1;229(1):203-14 |
1 | J:230611 Dierker T, Bachvarova V, Krause Y, Li JP, Kjellen L, Seidler DG, Vortkamp A, Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones. Matrix Biol. 2016 Jan;49:82-92 |
1 | J:317276 Dittmann K, Wuelling M, Uhmann A, Dullin C, Hahn H, Schweyer S, Vortkamp A, Wienands J, Inactivation of patched1 in murine chondrocytes causes spinal fusion without inflammation. Arthritis Rheumatol. 2014 Apr;66(4):831-40 |
1 | J:160493 Dy P, Smits P, Silvester A, Penzo-Mendez A, Dumitriu B, Han Y, de la Motte CA, Kingsley DM, Lefebvre V, Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. Dev Biol. 2010 May 15;341(2):346-59 |
1* | J:195901 Ehlen H, Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues. J Bone Miner Res. 2013;28(2):246-59 |
1 | J:202337 Estrada KD, Wang W, Retting KN, Chien CT, Elkhoury FF, Heuchel R, Lyons KM, Smad7 regulates terminal maturation of chondrocytes in the growth plate. Dev Biol. 2013 Oct 15;382(2):375-84 |
1 | J:111426 Ganss B, Kobayashi H, The zinc finger transcription factor Zfp60 is a negative regulator of cartilage differentiation. J Bone Miner Res. 2002 Dec;17(12):2151-60 |
1 | J:147878 Gao B, Hu J, Stricker S, Cheung M, Ma G, Law KF, Witte F, Briscoe J, Mundlos S, He L, Cheah KS, Chan D, A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range. Nature. 2009 Apr 30;458(7242):1196-200 |
1 | J:214984 Gonzalez-Martin MC, Mallo M, Ros MA, Long bone development requires a threshold of Hox function. Dev Biol. 2014 Aug 15;392(2):454-65 |
1 | J:74145 Gori F, Schipani E, Demay MB, Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development. J Cell Biochem. 2001 Apr 2-27;82(1):46-57 |
1 | J:191689 Gross S, Krause Y, Wuelling M, Vortkamp A, Hoxa11 and Hoxd11 regulate chondrocyte differentiation upstream of Runx2 and Shox2 in mice. PLoS One. 2012;7(8):e43553 |
1* | J:138379 Gu S, Wei N, Yu L, Fei J, Chen Y, Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice. Mech Dev. 2008 Aug;125(8):729-42 |
1 | J:150187 Guo X, Mak KK, Taketo MM, Yang Y, The Wnt/beta-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturation. PLoS One. 2009;4(6):e6067 |
1 | J:65293 Hebrok M, Kim SK, St Jacques B, McMahon AP, Melton DA, Regulation of pancreas development by hedgehog signaling. Development. 2000 Nov;127(22):4905-13 |
2 | J:104933 Hilton MJ, Gutierrez L, Martinez DA, Wells DE, EXT1 regulates chondrocyte proliferation and differentiation during endochondral bone development. Bone. 2005 Mar;36(3):379-86 |
1 | J:146280 Hirata M, Kugimiya F, Fukai A, Ohba S, Kawamura N, Ogasawara T, Kawasaki Y, Saito T, Yano F, Ikeda T, Nakamura K, Chung UI, Kawaguchi H, C/EBPbeta Promotes transition from proliferation to hypertrophic differentiation of chondrocytes through transactivation of p57. PLoS One. 2009;4(2):e4543 |
1 | J:160335 Huang X, Liu J, Ketova T, Fleming JT, Grover VK, Cooper MK, Litingtung Y, Chiang C, Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8422-7 |
1* | J:194983 Ideno H, Shimada A, Imaizumi K, Kimura H, Abe M, Nakashima K, Nifuji A, Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development. Gene Expr Patterns. 2013 Mar-Apr;13(3-4):84-90 |
1* | J:140470 Imuta Y, Nishioka N, Kiyonari H, Sasaki H, Short limbs, cleft palate, and delayed formation of flat proliferative chondrocytes in mice with targeted disruption of a putative protein kinase gene, Pkdcc (AW548124). Dev Dyn. 2008 Dec 18;238(1):210-222 |
1 | J:83260 Ivkovic S, Yoon BS, Popoff SN, Safadi FF, Libuda DE, Stephenson RC, Daluiski A, Lyons KM, Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development. Development. 2003 Jun;130(12):2779-91 |
1 | J:119288 Jacob AL, Smith C, Partanen J, Ornitz DM, Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation. Dev Biol. 2006 Aug 15;296(2):315-28 |
1* | J:38389 Jensen AM, Wallace VA, Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina. Development. 1997 Jan;124(2):363-71 |
1* | J:79831 Kawakami T, Kawcak T, Li YJ, Zhang W, Hu Y, Chuang PT, Mouse dispatched mutants fail to distribute hedgehog proteins and are defective in hedgehog signaling. Development. 2002 Dec;129(24):5753-65 |
1 | J:151258 Kolterud A, Grosse AS, Zacharias WJ, Walton KD, Kretovich KE, Madison BB, Waghray M, Ferris JE, Hu C, Merchant JL, Dlugosz AA, Kottmann AH, Gumucio DL, Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning. Gastroenterology. 2009 Aug;137(2):618-28 |
1 | J:92212 Koziel L, Kunath M, Kelly OG, Vortkamp A, Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification. Dev Cell. 2004 Jun;6(6):801-13 |
1 | J:102948 Koziel L, Wuelling M, Schneider S, Vortkamp A, Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation. Development. 2005 Dec;132(23):5249-60 |
1* | J:81315 Kunath M, Ludecke HJ, Vortkamp A, Expression of Trps1 during mouse embryonic development. Mech Dev. 2002 Dec;119 Suppl 1:S117-20 |
1 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
1 | J:178364 Lenton K, James AW, Manu A, Brugmann SA, Birker D, Nelson ER, Leucht P, Helms JA, Longaker MT, Indian hedgehog positively regulates calvarial ossification and modulates bone morphogenetic protein signaling. Genesis. 2011 Oct;49(10):784-96 |
1 | J:182649 Levi B, James AW, Nelson ER, Brugmann SA, Sorkin M, Manu A, Longaker MT, Role of Indian hedgehog signaling in palatal osteogenesis. Plast Reconstr Surg. 2011 Mar;127(3):1182-90 |
1 | J:75879 Liu Z, Xu J, Colvin JS, Ornitz DM, Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. Genes Dev. 2002 Apr 1;16(7):859-69 |
1* | J:73071 Long F, Zhang XM, Karp S, Yang Y, McMahon AP, Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development. 2001 Dec;128(24):5099-108 |
1 | J:125095 Lu J, Lian G, Lenkinski R, De Grand A, Vaid RR, Bryce T, Stasenko M, Boskey A, Walsh C, Sheen V, Filamin B mutations cause chondrocyte defects in skeletal development. Hum Mol Genet. 2007 Jul 15;16(14):1661-75 |
1 | J:152843 Luo J, Zhou W, Zhou X, Li D, Weng J, Yi Z, Cho SG, Li C, Yi T, Wu X, Li XY, de Crombrugghe B, Hook M, Liu M, Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development. 2009 Aug;136(16):2747-56 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1* | J:93152 Maclean HE, Kronenberg HM, Expression of Stra13 during mouse endochondral bone development. Gene Expr Patterns. 2004 Oct;4(6):633-6 |
1 | J:100378 MacLean HE, Kronenberg HM, Localization of Indian hedgehog and PTH/PTHrP receptor expression in relation to chondrocyte proliferation during mouse bone development. Dev Growth Differ. 2005 Feb;47(2):59-63 |
1 | J:193853 Makino Y, Takahashi Y, Tanabe R, Tamamura Y, Watanabe T, Haraikawa M, Hamagaki M, Hata K, Kanno J, Yoneda T, Saga Y, Goseki-Sone M, Kaneko K, Yamaguchi A, Iimura T, Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone. 2013 Mar;53(1):248-58 |
1 | J:152912 Matsumoto K, Li Y, Jakuba C, Sugiyama Y, Sayo T, Okuno M, Dealy CN, Toole BP, Takeda J, Yamaguchi Y, Kosher RA, Conditional inactivation of Has2 reveals a crucial role for hyaluronan in skeletal growth, patterning, chondrocyte maturation and joint formation in the developing limb. Development. 2009 Aug;136(16):2825-35 |
1 | J:296737 Matsuura VKSK, Yoshida CA, Komori H, Sakane C, Yamana K, Jiang Q, Komori T, Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice. Int J Mol Sci. 2020 Apr 12;21(8):2682 |
1* | J:86666 Michno K, Boras-Granic K, Mill P, Hui CC, Hamel PA, Shh expression is required for embryonic hair follicle but not mammary gland development. Dev Biol. 2003 Dec 1;264(1):153-65 |
1 | J:149225 Miclea RL, Karperien M, Bosch CA, van der Horst G, van der Valk MA, Kobayashi T, Kronenberg HM, Rawadi G, Akcakaya P, Lowik CW, Fodde R, Wit JM, Robanus-Maandag EC, Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors. BMC Dev Biol. 2009;9:26 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:205339 Mis EK, Liem KF Jr, Kong Y, Schwartz NB, Domowicz M, Weatherbee SD, Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length. Dev Biol. 2014 Jan 1;385(1):67-82 |
1 | J:170582 Mundy C, Yasuda T, Kinumatsu T, Yamaguchi Y, Iwamoto M, Enomoto-Iwamoto M, Koyama E, Pacifici M, Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine. Dev Biol. 2011 Mar 1;351(1):70-81 |
1* | J:74344 Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B, The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 2002 Jan 11;108(1):17-29 |
1 | J:316655 Oh SK, Shin JO, Baek JI, Lee J, Bae JW, Ankamerddy H, Kim MJ, Huh TL, Ryoo ZY, Kim UK, Bok J, Lee KY, Pannexin 3 is required for normal progression of skeletal development in vertebrates. FASEB J. 2015 Nov;29(11):4473-84 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1 | J:258274 Patra D, DeLassus E, Mueller J, Abou-Ezzi G, Sandell LJ, Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice. Biol Open. 2018 Feb 22;7(2):bio032094 |
1* | J:199462 Probst S, Zeller R, Zuniga A, The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development. Differentiation. 2013 Apr-Jun;85(4-5):121-30 |
1 | J:128917 Provot S, Nachtrab G, Paruch J, Chen AP, Silva A, Kronenberg HM, A-raf and B-raf are dispensable for normal endochondral bone development, and parathyroid hormone-related peptide suppresses extracellular signal-regulated kinase activation in hypertrophic chondrocytes. Mol Cell Biol. 2008 Jan;28(1):344-57 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1 | J:147287 Retting KN, Song B, Yoon BS, Lyons KM, BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation. Development. 2009 Apr;136(7):1093-104 |
1 | J:163175 Rice DP, Connor EC, Veltmaat JM, Lana-Elola E, Veistinen L, Tanimoto Y, Bellusci S, Rice R, Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation. Hum Mol Genet. 2010 Sep 1;19(17):3457-67 |
1 | J:76480 Robledo RF, Rajan L, Li X, Lufkin T, The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev. 2002 May 1;16(9):1089-101 |
1 | J:124105 Ruiz-Perez VL, Blair HJ, Rodriguez-Andres ME, Blanco MJ, Wilson A, Liu YN, Miles C, Peters H, Goodship JA, Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. Development. 2007 Aug;134(16):2903-12 |
1 | J:340421 Ruscitto A, Chen P, Tosa I, Wang Z, Zhou G, Safina I, Wei R, Morel MM, Koch A, Forman M, Reeve G, Lecholop MK, Wilson M, Bonthius D, Chen M, Ono M, Wang TC, Yao H, Embree MC, Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity. Cell Stem Cell. 2023 Sep 7;30(9):1179-1198.e7 |
1 | J:279005 Schroeder N, Wuelling M, Hoffmann D, Brand-Saberi B, Vortkamp A, Atoh8 acts as a regulator of chondrocyte proliferation and differentiation in endochondral bones. PLoS One. 2019;14(8):e0218230 |
1 | J:167067 Seidel K, Ahn CP, Lyons D, Nee A, Ting K, Brownell I, Cao T, Carano RA, Curran T, Schober M, Fuchs E, Joyner A, Martin GR, de Sauvage FJ, Klein OD, Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor. Development. 2010 Nov;137(22):3753-61 |
1* | J:143455 Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Al Awqati Q, Ballabio A, Karsenty G, Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification. Genes Dev. 2008 Oct 1;22(19):2645-50 |
1 | J:187998 Shung CY, Ota S, Zhou ZQ, Keene DR, Hurlin PJ, Disruption of a Sox9-beta-catenin circuit by mutant Fgfr3 in thanatophoric dysplasia type II. Hum Mol Genet. 2012 Nov 1;21(21):4628-44 |
1* | J:80666 Smits P, Li P, Mandel J, Zhang Z, Deng JM, Behringer RR, de Croumbrugghe B, Lefebvre V, The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001 Aug;1(2):277-90 |
1 | J:134924 Spagnoli A, O'Rear L, Chandler RL, Granero-Molto F, Mortlock DP, Gorska AE, Weis JA, Longobardi L, Chytil A, Shimer K, Moses HL, TGF-beta signaling is essential for joint morphogenesis. J Cell Biol. 2007 Jun 18;177(6):1105-17 |
1 | J:191584 Sueyoshi T, Yamamoto K, Akiyama H, Conditional deletion of Tgfbr2 in hypertrophic chondrocytes delays terminal chondrocyte differentiation. Matrix Biol. 2012 Jul;31(6):352-9 |
1* | J:67784 Takeda S, Bonnamy JP, Owen MJ, Ducy P, Karsenty G, Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. Genes Dev. 2001 Feb 15;15(4):467-81 |
1 | J:84273 Terpstra L, Prud'homme J, Arabian A, Takeda S, Karsenty G, Dedhar S, St-Arnaud R, Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes. J Cell Biol. 2003 Jul 7;162(1):139-48 |
1 | J:52419 Tsumaki N, Tanaka K, Arikawa-Hirasawa E, Nakase T, Kimura T, Thomas JT, Ochi T, Luyten FP, Yamada Y, Role of CDMP-1 in skeletal morphogenesis: promotion of mesenchymal cell recruitment and chondrocyte differentiation. J Cell Biol. 1999 Jan 11;144(1):161-73 |
2* | J:39298 Valentini RP, Brookhiser WT, Park J, Yang T, Briggs J, Dressler G , Holzman LB, Post-translational processing and renal expression of mouse Indian hedgehog. J Biol Chem. 1997 Mar 28;272(13):8466-73 |
1 | J:112002 van der Weyden L, Wei L, Luo J, Yang X, Birk DE, Adams DJ, Bradley A, Chen Q, Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis. Am J Pathol. 2006 Aug;169(2):515-27 |
1* | J:76742 Vortkamp A, Lee K, Lanske B, Segre GV, Kronenberg HM, Tabin CJ, Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein. Science. 1996 Aug 2;273(5275):613-22 |
2 | J:324690 Wang H, Zheng C, Lu W, He T, Fan J, Wang C, Jie Q, Chan D, Cheah KSE, Yang L, Hedgehog signaling orchestrates cartilage-to-bone transition independently of Smoothened. Matrix Biol. 2022 Apr 23; |
1* | J:154906 Wang W, Lian N, Li L, Moss HE, Wang W, Perrien DS, Elefteriou F, Yang X, Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription. Development. 2009 Dec;136(24):4143-53 |
1 | J:177115 Wang Y, Liu C, Rohr J, Liu H, He F, Yu J, Sun C, Li L, Gu S, Chen Y, Tissue interaction is required for glenoid fossa development during temporomandibular joint formation. Dev Dyn. 2011 Nov;240(11):2466-73 |
1* | J:200760 Wang Y, Zheng Y, Chen D, Chen Y, Enhanced BMP signaling prevents degeneration and leads to endochondral ossification of Meckel's cartilage in mice. Dev Biol. 2013 Sep 15;381(2):301-11 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1 | J:149459 Wuelling M, Kaiser FJ, Buelens LA, Braunholz D, Shivdasani RA, Depping R, Vortkamp A, Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. Dev Biol. 2009 Apr 1;328(1):40-53 |
1 | J:283400 Wuelling M, Schneider S, Schrother VA, Waterkamp C, Hoffmann D, Vortkamp A, Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of chondrocyte hypertrophy. Dev Biol. 2020 Jan 1;457(1):104-118 |
1 | J:320311 Yang L, Gu S, Ye W, Song Y, Chen Y, Augmented Indian hedgehog signaling in cranial neural crest cells leads to craniofacial abnormalities and dysplastic temporomandibular joint in mice. Cell Tissue Res. 2016 Apr;364(1):105-15 |
1 | J:360708 Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K, Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase. Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2320070121 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
1 | J:87592 Zhou HM, Weskamp G, Chesneau V, Sahin U, Vortkamp A, Horiuchi K, Chiusaroli R, Hahn R, Wilkes D, Fisher P, Baron R, Manova K, Basson CT, Hempstead B, Blobel CP, Essential role for ADAM19 in cardiovascular morphogenesis. Mol Cell Biol. 2004 Jan;24(1):96-104 |
1 | J:172282 Zhou ZQ, Shung CY, Ota S, Akiyama H, Keene DR, Hurlin PJ, Sequential and coordinated actions of c-Myc and N-Myc control appendicular skeletal development. PLoS One. 2011;6(4):e18795 |
1 | J:155388 Zhu H, Bendall AJ, Dlx5 Is a cell autonomous regulator of chondrocyte hypertrophy in mice and functionally substitutes for Dlx6 during endochondral ossification. PLoS One. 2009;4(11):e8097 |
Ikbkb inhibitor of kappaB kinase beta (Synonyms: IKK-2, IKK2, IKK[b], IKK-beta, IKKbeta) | |
Results | Reference |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
Ikbke inhibitor of kappaB kinase epsilon (Synonyms: IKKepsilon, IKK-i) | |
Results | Reference |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
Ikzf1 IKAROS family zinc finger 1 (Synonyms: 5832432G11Rik, Ikaros, LyF-1, Zfpn1a1) | |
Results | Reference |
1 | J:285747 Liu S, Liu X, Li S, Huang X, Qian H, Jin K, Xiang M, Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5016-5027 |
1 | J:316266 Martin-Ibanez R, Crespo E, Esgleas M, Urban N, Wang B, Waclaw R, Georgopoulos K, Martinez S, Campbell K, Vicario-Abejon C, Alberch J, Chan S, Kastner P, Rubenstein JL, Canals JM, Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons. Stem Cells Dev. 2012 Aug 10;21(12):2239-51 |
1* | J:39856 Scott EW, Fisher RC, Olson MC, Kehrli EW, Simon MC, Singh H, PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors. Immunity. 1997 Apr;6(4):437-47 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1 | J:263059 Tenno M, Kojo S, Lawir DF, Hess I, Shiroguchi K, Ebihara T, Endo TA, Muroi S, Satoh R, Kawamoto H, Boehm T, Taniuchi I, Cbfbeta2 controls differentiation of and confers homing capacity to prethymic progenitors. J Exp Med. 2018 Feb 5;215(2):595-610 |
Ikzf2 IKAROS family zinc finger 2 (Synonyms: A730095J18Rik, Helios, Zfpn1a2) | |
Results | Reference |
1* | J:283039 Giralt A, Brito V, Pardo M, Rubio SE, Marion-Poll L, Martin-Ibanez R, Zamora-Moratalla A, Bosch C, Ballesteros JJ, Blasco E, Garcia-Torralba A, Pascual M, Pumarola M, Alberch J, Gines S, Martin ED, Segovia J, Soriano E, Canals JM, Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation. Exp Neurol. 2020 Jan;323:113095 |
2 | J:316266 Martin-Ibanez R, Crespo E, Esgleas M, Urban N, Wang B, Waclaw R, Georgopoulos K, Martinez S, Campbell K, Vicario-Abejon C, Alberch J, Chan S, Kastner P, Rubenstein JL, Canals JM, Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons. Stem Cells Dev. 2012 Aug 10;21(12):2239-51 |
1 | J:240536 Martin-Ibanez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Garcia-Diaz Barriga G, Edel MJ, Vicario-Abejon C, Alberch J, Girault JA, Chan S, Kastner P, Canals JM, Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017 Apr 15;144(8):1566-1577 |
Ikzf4 IKAROS family zinc finger 4 (Synonyms: A630026H08Rik, Eos, Zfpn1a4) | |
Results | Reference |
1 | J:333564 Javed A, Santos-Franca PL, Mattar P, Cui A, Kassem F, Cayouette M, Ikaros family proteins redundantly regulate temporal patterning in the developing mouse retina. Development. 2023 Jan 15;150(2):dev200436 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Ikzf5 IKAROS family zinc finger 5 (Synonyms: 2610034F18Rik, Zfpn1a5) | |
Results | Reference |
1 | J:240536 Martin-Ibanez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Garcia-Diaz Barriga G, Edel MJ, Vicario-Abejon C, Alberch J, Girault JA, Chan S, Kastner P, Canals JM, Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017 Apr 15;144(8):1566-1577 |
Il1a interleukin 1 alpha (Synonyms: Il-1a) | |
Results | Reference |
1 | J:21326 Deman J, Humblet C, Martin MT, Boniver J, Defresne MP, Analysis by in situ hybridization of cytokine mRNA expression in the murine developing thymus. Int Immunol. 1994 Oct;6(10):1613-9 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:44503 Montgomery RA, Dallman MJ, Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny. Cytokine. 1997 Oct;9(10):717-26 |
1* | J:55762 Montgomery RA, Dallman MJ, Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J Immunol. 1991 Jul 15;147(2):554-60 |
Il1b interleukin 1 beta (Synonyms: IL-1B, IL-1beta) | |
Results | Reference |
1* | J:35158 Deman J, Van Meurs M, Claassen E, Humblet C, Boniver J, Defresne MP, In vivo expression of interleukin-1 beta (IL-1 beta), IL-2, IL-4, IL-6, tumour necrosis factor-alpha and interferon-gamma in the fetal murine thymus. Immunology. 1996 Sep;89(1):152-7 |
1 | J:307825 Fisher AL, Sangkhae V, Balusikova K, Palaskas NJ, Ganz T, Nemeth E, Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy. Nat Commun. 2021 Jun 29;12(1):4026 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:269295 Kang TB, Jeong JS, Yang SH, Kovalenko A, Wallach D, Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3. Cell Death Differ. 2018 Jun;25(6):1107-1117 |
1* | J:55762 Montgomery RA, Dallman MJ, Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J Immunol. 1991 Jul 15;147(2):554-60 |
1 | J:135431 Salminen A, Paananen R, Vuolteenaho R, Metsola J, Ojaniemi M, Autio-Harmainen H, Hallman M, Maternal endotoxin-induced preterm birth in mice: fetal responses in toll-like receptors, collectins, and cytokines. Pediatr Res. 2008 Mar;63(3):280-6 |
Il1rap interleukin 1 receptor accessory protein (Synonyms: 6430709H04Rik, IL-1R AcP, IL-1RAcP) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Il1rapl2 interleukin 1 receptor accessory protein-like 2 | |
Results | Reference |
1* | J:72364 Ferrante MI, Ghiani M, Bulfone A, Franco B, IL1RAPL2 maps to Xq22 and is specifically expressed in the central nervous system. Gene. 2001 Sep 19;275(2):217-21 |
Il1rl1 interleukin 1 receptor-like 1 (Synonyms: DER4, Fit-1, Ly84, St2, ST2, ST2L, St2-rs1, T1, T1 gene, T1/ST2) | |
Results | Reference |
1* | J:17250 Bergers G, Reikerstorfer A, Braselmann S, Graninger P, Busslinger M, Alternative promoter usage of the Fos-responsive gene Fit-1 generates mRNA isoforms coding for either secreted or membrane-bound proteins related to the IL-1 receptor. EMBO J. 1994 Mar 1;13(5):1176-88 |
Il2 interleukin 2 (Synonyms: IL-2) | |
Results | Reference |
1 | J:21326 Deman J, Humblet C, Martin MT, Boniver J, Defresne MP, Analysis by in situ hybridization of cytokine mRNA expression in the murine developing thymus. Int Immunol. 1994 Oct;6(10):1613-9 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:44503 Montgomery RA, Dallman MJ, Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny. Cytokine. 1997 Oct;9(10):717-26 |
1* | J:55762 Montgomery RA, Dallman MJ, Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J Immunol. 1991 Jul 15;147(2):554-60 |
1* | J:49918 Murray AM, Simm B, Beagley KW, Cytokine gene expression in murine fetal intestine: potential for extrathymic T cell development. Cytokine. 1998 May;10(5):337-45 |
Il2rb interleukin 2 receptor, beta chain (Synonyms: CD122, IL-15Rbeta, IL15Rbeta, IL-15 receptor beta chain, IL-2/15Rbeta, Il-2Rbeta) | |
Results | Reference |
1* | J:44503 Montgomery RA, Dallman MJ, Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny. Cytokine. 1997 Oct;9(10):717-26 |
1* | J:55762 Montgomery RA, Dallman MJ, Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J Immunol. 1991 Jul 15;147(2):554-60 |
Il2rg interleukin 2 receptor, gamma chain (Synonyms: CD132, common cytokine receptor gamma chain, common gamma chain, gamma(c), gammaC, gamma C receptor, [g]c, gc) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Il3 interleukin 3 (Synonyms: BPA, Csfmu, HCGF, Il-3, MCGF, PSF) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:44503 Montgomery RA, Dallman MJ, Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny. Cytokine. 1997 Oct;9(10):717-26 |
1* | J:55762 Montgomery RA, Dallman MJ, Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J Immunol. 1991 Jul 15;147(2):554-60 |
1 | J:222261 Tan KS, Inoue T, Kulkeaw K, Tanaka Y, Lai MI, Sugiyama D, Localized SCF and IGF-1 secretion enhances erythropoiesis in the spleen of murine embryos. Biol Open. 2015;4(5):596-607 |
Il4 interleukin 4 (Synonyms: Il-4) | |
Results | Reference |
1 | J:21326 Deman J, Humblet C, Martin MT, Boniver J, Defresne MP, Analysis by in situ hybridization of cytokine mRNA expression in the murine developing thymus. Int Immunol. 1994 Oct;6(10):1613-9 |
1* | J:35158 Deman J, Van Meurs M, Claassen E, Humblet C, Boniver J, Defresne MP, In vivo expression of interleukin-1 beta (IL-1 beta), IL-2, IL-4, IL-6, tumour necrosis factor-alpha and interferon-gamma in the fetal murine thymus. Immunology. 1996 Sep;89(1):152-7 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:44503 Montgomery RA, Dallman MJ, Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny. Cytokine. 1997 Oct;9(10):717-26 |
1* | J:55762 Montgomery RA, Dallman MJ, Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J Immunol. 1991 Jul 15;147(2):554-60 |
1* | J:49918 Murray AM, Simm B, Beagley KW, Cytokine gene expression in murine fetal intestine: potential for extrathymic T cell development. Cytokine. 1998 May;10(5):337-45 |
1 | J:135431 Salminen A, Paananen R, Vuolteenaho R, Metsola J, Ojaniemi M, Autio-Harmainen H, Hallman M, Maternal endotoxin-induced preterm birth in mice: fetal responses in toll-like receptors, collectins, and cytokines. Pediatr Res. 2008 Mar;63(3):280-6 |
Il4ra interleukin 4 receptor, alpha (Synonyms: CD124, Il4r, IL-4 receptor alpha chain) | |
Results | Reference |
1* | J:44503 Montgomery RA, Dallman MJ, Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny. Cytokine. 1997 Oct;9(10):717-26 |
Il5 interleukin 5 (Synonyms: Il-5) | |
Results | Reference |
1* | J:44503 Montgomery RA, Dallman MJ, Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny. Cytokine. 1997 Oct;9(10):717-26 |
1* | J:55762 Montgomery RA, Dallman MJ, Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J Immunol. 1991 Jul 15;147(2):554-60 |
Il6 interleukin 6 (Synonyms: Il-6) | |
Results | Reference |
1* | J:17727 Burns TM, Clough JA, Klein RM, Wood GW, Berman NE, Developmental regulation of cytokine expression in the mouse brain. Growth Factors. 1993;9(4):253-8 |
1 | J:21326 Deman J, Humblet C, Martin MT, Boniver J, Defresne MP, Analysis by in situ hybridization of cytokine mRNA expression in the murine developing thymus. Int Immunol. 1994 Oct;6(10):1613-9 |
1* | J:35158 Deman J, Van Meurs M, Claassen E, Humblet C, Boniver J, Defresne MP, In vivo expression of interleukin-1 beta (IL-1 beta), IL-2, IL-4, IL-6, tumour necrosis factor-alpha and interferon-gamma in the fetal murine thymus. Immunology. 1996 Sep;89(1):152-7 |
1 | J:307825 Fisher AL, Sangkhae V, Balusikova K, Palaskas NJ, Ganz T, Nemeth E, Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy. Nat Commun. 2021 Jun 29;12(1):4026 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:68367 Melnick M, Chen H, Zhou YM, Jaskoll T, Interleukin-6 signaling and embryonic mouse submandibular salivary gland morphogenesis. Cells Tissues Organs. 2001;168(4):233-45 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1* | J:44503 Montgomery RA, Dallman MJ, Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny. Cytokine. 1997 Oct;9(10):717-26 |
1* | J:55762 Montgomery RA, Dallman MJ, Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J Immunol. 1991 Jul 15;147(2):554-60 |
1 | J:321171 Safwan-Zaiter H, Wagner N, Michiels JF, Wagner KD, Dynamic Spatiotemporal Expression Pattern of the Senescence-Associated Factor p16Ink4a in Development and Aging. Cells. 2022 Feb 4;11(3) |
1 | J:135431 Salminen A, Paananen R, Vuolteenaho R, Metsola J, Ojaniemi M, Autio-Harmainen H, Hallman M, Maternal endotoxin-induced preterm birth in mice: fetal responses in toll-like receptors, collectins, and cytokines. Pediatr Res. 2008 Mar;63(3):280-6 |
1 | J:314320 Wang H, Kane AW, Lee C, Ahn S, Gli3 repressor controls cell fates and cell adhesion for proper establishment of neurogenic niche. Cell Rep. 2014 Aug 21;8(4):1093-104 |
Il6ra interleukin 6 receptor, alpha (Synonyms: CD126, Il6r, IL-6R, IL-6 receptor alpha chain) | |
Results | Reference |
1 | J:314320 Wang H, Kane AW, Lee C, Ahn S, Gli3 repressor controls cell fates and cell adhesion for proper establishment of neurogenic niche. Cell Rep. 2014 Aug 21;8(4):1093-104 |
Il6st interleukin 6 signal transducer (Synonyms: 5133400A03Rik, CD130, D13Ertd699e, gp130) | |
Results | Reference |
2 | J:314320 Wang H, Kane AW, Lee C, Ahn S, Gli3 repressor controls cell fates and cell adhesion for proper establishment of neurogenic niche. Cell Rep. 2014 Aug 21;8(4):1093-104 |
Il7 interleukin 7 (Synonyms: A630026I06Rik, hlb368, Il-7) | |
Results | Reference |
1* | J:120667 Bouzin C, Clotman F, Renauld JC, Lemaigre FP, Rousseau GG, The onecut transcription factor hepatocyte nuclear factor-6 controls B lymphopoiesis in fetal liver. J Immunol. 2003 Aug 1;171(3):1297-303 |
1* | J:189751 Hara T, Shitara S, Imai K, Miyachi H, Kitano S, Yao H, Tani-ichi S, Ikuta K, Identification of IL-7-producing cells in primary and secondary lymphoid organs using IL-7-GFP knock-in mice. J Immunol. 2012 Aug 15;189(4):1577-84 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:44503 Montgomery RA, Dallman MJ, Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny. Cytokine. 1997 Oct;9(10):717-26 |
1* | J:55762 Montgomery RA, Dallman MJ, Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J Immunol. 1991 Jul 15;147(2):554-60 |
1* | J:49918 Murray AM, Simm B, Beagley KW, Cytokine gene expression in murine fetal intestine: potential for extrathymic T cell development. Cytokine. 1998 May;10(5):337-45 |
1 | J:95866 Zamisch M, Moore-Scott B, Su DM, Lucas PJ, Manley N, Richie ER, Ontogeny and regulation of IL-7-expressing thymic epithelial cells. J Immunol. 2005 Jan 1;174(1):60-7 |
Il7r interleukin 7 receptor (Synonyms: CD127, IL-7Ralpha, IL-7 receptor alpha chain) | |
Results | Reference |
1 | J:159868 Benezech C, White A, Mader E, Serre K, Parnell S, Pfeffer K, Ware CF, Anderson G, Caamano JH, Ontogeny of stromal organizer cells during lymph node development. J Immunol. 2010 Apr 15;184(8):4521-30 |
1 | J:87395 Eberl G, Marmon S, Sunshine MJ, Rennert PD, Choi Y, Littman DR, An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat Immunol. 2004 Jan;5(1):64-73 |
1 | J:137812 Vondenhoff MF, Desanti GE, Cupedo T, Bertrand JY, Cumano A, Kraal G, Mebius RE, Golub R, Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner. J Leukoc Biol. 2008 Jul;84(1):152-61 |
1 | J:150308 Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009 May 1;182(9):5439-45 |
1 | J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34 |
Il9 interleukin 9 (Synonyms: Il-9, P40) | |
Results | Reference |
1* | J:49918 Murray AM, Simm B, Beagley KW, Cytokine gene expression in murine fetal intestine: potential for extrathymic T cell development. Cytokine. 1998 May;10(5):337-45 |
Il10 interleukin 10 (Synonyms: cytokine synthesis inhibitory factor, IL-10) | |
Results | Reference |
1* | J:44503 Montgomery RA, Dallman MJ, Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny. Cytokine. 1997 Oct;9(10):717-26 |
1 | J:135431 Salminen A, Paananen R, Vuolteenaho R, Metsola J, Ojaniemi M, Autio-Harmainen H, Hallman M, Maternal endotoxin-induced preterm birth in mice: fetal responses in toll-like receptors, collectins, and cytokines. Pediatr Res. 2008 Mar;63(3):280-6 |
Il11 interleukin 11 (Synonyms: IL-11) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
Il11ra1 interleukin 11 receptor subunit alpha 1 (Synonyms: Il-11ra, Il11ra, Il-11ra-alpha, NR1) | |
Results | Reference |
1 | J:39945 Davidson AJ, Freeman SA, Crosier KE, Wood CR, Crosier PS, Expression of murine interleukin 11 and its receptor alpha-chain in adult and embryonic tissues. Stem Cells. 1997;15(2):119-24 |
Il12a interleukin 12a (Synonyms: IL-12p35, p35) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
Il13 interleukin 13 (Synonyms: Il-13) | |
Results | Reference |
1* | J:49918 Murray AM, Simm B, Beagley KW, Cytokine gene expression in murine fetal intestine: potential for extrathymic T cell development. Cytokine. 1998 May;10(5):337-45 |
Il15 interleukin 15 | |
Results | Reference |
1* | J:49918 Murray AM, Simm B, Beagley KW, Cytokine gene expression in murine fetal intestine: potential for extrathymic T cell development. Cytokine. 1998 May;10(5):337-45 |
Il17b interleukin 17B (Synonyms: 1110006O16Rik, 1700006N07Rik, Zcyto7) | |
Results | Reference |
2* | J:94618 You Z, DuRaine G, Tien JY, Lee C, Moseley TA, Reddi AH, Expression of interleukin-17B in mouse embryonic limb buds and regulation by BMP-7 and bFGF. Biochem Biophys Res Commun. 2005 Jan 21;326(3):624-31 |
Il17ra interleukin 17 receptor A (Synonyms: Il17r, VDw217) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
Il17rd interleukin 17 receptor D (Synonyms: 2810004A10Rik, Sef, Sef-S) | |
Results | Reference |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
Il18 interleukin 18 (Synonyms: Igif, Il-18) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Il33 interleukin 33 (Synonyms: 9230117N10Rik, Il1f11, Il-33, NF-HEV) | |
Results | Reference |
1 | J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005 |
Il34 interleukin 34 (Synonyms: 2010004A03Rik) | |
Results | Reference |
1 | J:234684 Wang Y, Bugatti M, Ulland TK, Vermi W, Gilfillan S, Colonna M, Nonredundant roles of keratinocyte-derived IL-34 and neutrophil-derived CSF1 in Langerhans cell renewal in the steady state and during inflammation. Eur J Immunol. 2016 Mar;46(3):552-9 |
Ilk integrin linked kinase (Synonyms: ESTM24) | |
Results | Reference |
1 | J:316298 Dejaeger M, Bohm AM, Dirckx N, Devriese J, Nefyodova E, Cardoen R, St-Arnaud R, Tournoy J, Luyten FP, Maes C, Integrin-Linked Kinase Regulates Bone Formation by Controlling Cytoskeletal Organization and Modulating BMP and Wnt Signaling in Osteoprogenitors. J Bone Miner Res. 2017 Oct;32(10):2087-2102 |
1 | J:84273 Terpstra L, Prud'homme J, Arabian A, Takeda S, Karsenty G, Dedhar S, St-Arnaud R, Reduced chondrocyte proliferation and chondrodysplasia in mice lacking the integrin-linked kinase in chondrocytes. J Cell Biol. 2003 Jul 7;162(1):139-48 |
1 | J:281878 Yook C, Kim K, Kim D, Kang H, Kim SG, Kim E, Kim SY, A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice. Front Mol Neurosci. 2019;12:241 |
Ina internexin neuronal intermediate filament protein, alpha (Synonyms: MGC:25352, NF-66, NF66) | |
Results | Reference |
1 | J:54791 Faussone-Pellegrini MS, Matini P, DeFelici M, The cytoskeleton of the myenteric neurons during murine embryonic life. Anat Embryol (Berl). 1999 May;199(5):459-69 |
1 | J:241012 Lee M, Yoon J, Song H, Lee B, Lam DT, Yoon J, Baek K, Clevers H, Jeong Y, Tcf7l2 plays crucial roles in forebrain development through regulation of thalamic and habenular neuron identity and connectivity. Dev Biol. 2017 Apr 01;424(1):62-76 |
2 | J:306063 Morandell J, Schwarz LA, Basilico B, Tasciyan S, Dimchev G, Nicolas A, Sommer C, Kreuzinger C, Dotter CP, Knaus LS, Dobler Z, Cacci E, Schur FKM, Danzl JG, Novarino G, Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development. Nat Commun. 2021 May 24;12(1):3058 |
Incenp inner centromere protein (Synonyms: 2700067E22Rik) | |
Results | Reference |
1* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
Inha inhibin alpha | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:39719 Ying SY, Zhan Y, Zhang Z, Changes in the immunoreactivity for inhibin in mouse retina during development of photoreceptor cells. Dev Neurosci. 1997;19(2):184-8 |
Inhba inhibin beta-A (Synonyms: activin beta-A) | |
Results | Reference |
1 | J:307093 Amato CM, Yao HH, Developmental and sexual dimorphic atlas of the prenatal mouse external genitalia at the single-cell level. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2103856118 |
1 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
3* | J:216602 Bryant SL, Francis JC, Lokody IB, Wang H, Risbridger GP, Loveland KL, Swain A, Sex specific retinoic acid signaling is required for the initiation of urogenital sinus bud development. Dev Biol. 2014 Nov 15;395(2):209-17 |
1 | J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:199186 Juuri E, Saito K, Lefebvre S, Michon F, Establishment of crown-root domain borders in mouse incisor. Gene Expr Patterns. 2013 Oct;13(7):255-64 |
1 | J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:31961 Schmitt J, Hotten G, Jenkins NA, Gilbert DJ, Copeland NG, Pohl J, Schrewe H, Structure, chromosomal localization, and expression analysis of the mouse inhibin/activin beta C (Inhbc) gene. Genomics. 1996 Mar 15;32(3):358-66 |
1 | J:91704 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Wankell M, Werner S, Thesleff I, Modulation of activin/bone morphogenetic protein signaling by follistatin is required for the morphogenesis of mouse molar teeth. Dev Dyn. 2004 Sep;231(1):98-108 |
1 | J:94518 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Werner S, Thesleff I, Follistatin regulates enamel patterning in mouse incisors by asymmetrically inhibiting BMP signaling and ameloblast differentiation. Dev Cell. 2004 Nov;7(5):719-30 |
1* | J:173972 Zhao H, Li S, Han D, Kaartinen V, Chai Y, Alk5-mediated transforming growth factor beta signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol. 2011 May;31(10):2079-89 |
Inhbb inhibin beta-B (Synonyms: activin beta-B) | |
Results | Reference |
1 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
1 | J:152858 Garcia-Ortiz JE, Pelosi E, Omari S, Nedorezov T, Piao Y, Karmazin J, Uda M, Cao A, Cole SW, Forabosco A, Schlessinger D, Ottolenghi C, Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Dev Biol. 2009;9:36 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:63347 Maldonado TS, Kadison AS, Crisera CA, Grau JB, Alkasab SL, Longaker MT, Gittes GK, Ontogeny of activin B and follistatin in developing embryonic mouse pancreas: implications for lineage selection. J Gastrointest Surg. 2000 May-Jun;4(3):269-75 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:31961 Schmitt J, Hotten G, Jenkins NA, Gilbert DJ, Copeland NG, Pohl J, Schrewe H, Structure, chromosomal localization, and expression analysis of the mouse inhibin/activin beta C (Inhbc) gene. Genomics. 1996 Mar 15;32(3):358-66 |
1 | J:339937 Smith KS, Bihannic L, Gudenas BL, Haldipur P, Tao R, Gao Q, Li Y, Aldinger KA, Iskusnykh IY, Chizhikov VV, Scoggins M, Zhang S, Edwards A, Deng M, Glass IA, Overman LM, Millman J, Sjoboen AH, Hadley J, Golser J, Mankad K, Sheppard H, Onar-Thomas A, Gajjar A, Robinson GW, Hovestadt V, Orr BA, Patay Z, Millen KJ, Northcott PA, Unified rhombic lip origins of group 3 and group 4 medulloblastoma. Nature. 2022 Sep;609(7929):1012-1020 |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
Inhbc inhibin beta-C (Synonyms: activin beta-C) | |
Results | Reference |
1* | J:110815 Lau AL, Kumar TR, Nishimori K, Bonadio J, Matzuk MM, Activin betaC and betaE genes are not essential for mouse liver growth, differentiation, and regeneration. Mol Cell Biol. 2000 Aug;20(16):6127-37 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:31961 Schmitt J, Hotten G, Jenkins NA, Gilbert DJ, Copeland NG, Pohl J, Schrewe H, Structure, chromosomal localization, and expression analysis of the mouse inhibin/activin beta C (Inhbc) gene. Genomics. 1996 Mar 15;32(3):358-66 |
Inhbe inhibin beta-E (Synonyms: activin beta-E, activin betaE) | |
Results | Reference |
1* | J:110815 Lau AL, Kumar TR, Nishimori K, Bonadio J, Matzuk MM, Activin betaC and betaE genes are not essential for mouse liver growth, differentiation, and regeneration. Mol Cell Biol. 2000 Aug;20(16):6127-37 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
Inka2 inka box actin regulator 2 (Synonyms: 6530418L21Rik, Fam212b, Inka2) | |
Results | Reference |
1* | J:226855 Iwasaki Y, Yumoto T, Sakakibara S, Expression profiles of inka2 in the murine nervous system. Gene Expr Patterns. 2015 Sep-Nov;19(1-2):83-97 |
Inpp5b inositol polyphosphate-5-phosphatase B (Synonyms: 75kDa) | |
Results | Reference |
1* | J:47884 Janne PA, Suchy SF, Bernard D, MacDonald M, Crawley J, Grinberg A , Wynshaw-Boris A , Westphal H , Nussbaum RL, Functional overlap between murine Inpp5b and Ocrl1 may explain why deficiency of the murine ortholog for OCRL1 does not cause Lowe syndrome in mice. J Clin Invest. 1998 May 15;101(10):2042-53 |
Inpp5f inositol polyphosphate-5-phosphatase F (Synonyms: 5830435P03Rik, cI-27, mKIAA0966, SAC2) | |
Results | Reference |
1* | J:99122 Choi JD, Underkoffler LA, Wood AJ, Collins JN, Williams PT, Golden JA, Schuster EF Jr, Loomes KM, Oakey RJ, A novel variant of inpp5f is imprinted in brain, and its expression is correlated with differential methylation of an internal CpG island. Mol Cell Biol. 2005 Jul;25(13):5514-22 |
1* | J:173504 Yan C, Hongjuan H, Yanjiang X, Zhengbin H, Kai L, Fengwei Z, Jing H, Qiong W, Expression patterns of imprinted gene Inpp5f-v3 during mouse brain development. J Mol Histol. 2011 Apr;42(2):167-73 |
Ins1 insulin I | |
Results | Reference |
1 | J:219809 Afelik S, Pool B, Schmerr M, Penton C, Jensen J, Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development. Dev Biol. 2015 Mar 15;399(2):204-17 |
1 | J:70719 Allen-Jennings AE, Hartman MG, Kociba GJ, Hai T, The roles of atf3 in glucose homeostasis. a transgenic mouse model with liver dysfunction and defects in endocrine pancreas. J Biol Chem. 2001 Aug 3;276(31):29507-14 |
2 | J:156329 Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L, Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. J Biol Chem. 2009 Nov 6;284(45):31236-48 |
1 | J:305792 Ansarullah, Jain C, Far FF, Homberg S, Wissmiller K, von Hahn FG, Raducanu A, Schirge S, Sterr M, Bilekova S, Siehler J, Wiener J, Oppenlander L, Morshedi A, Bastidas-Ponce A, Collden G, Irmler M, Beckers J, Feuchtinger A, Grzybek M, Ahlbrecht C, Feederle R, Plettenburg O, Muller TD, Meier M, Tschop MH, Coskun U, Lickert H, Inceptor counteracts insulin signalling in beta-cells to control glycaemia. Nature. 2021 Feb;590(7845):326-331 |
1 | J:119565 Boyer DF, Fujitani Y, Gannon M, Powers AC, Stein RW, Wright CV, Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression. Dev Biol. 2006 Oct 15;298(2):616-31 |
1 | J:116552 Brissova M, Shostak A, Shiota M, Wiebe PO, Poffenberger G, Kantz J, Chen Z, Carr C, Jerome WG, Chen J, Baldwin HS, Nicholson W, Bader DM, Jetton T, Gannon M, Powers AC, Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function. Diabetes. 2006 Nov;55(11):2974-85 |
1 | J:255164 Broche B, Ben Fradj S, Aguilar E, Sancerni T, Benard M, Makaci F, Berthault C, Scharfmann R, Alves-Guerra MC, Duvillie B, Mitochondrial Protein UCP2 Controls Pancreas Development. Diabetes. 2018 Jan;67(1):78-84 |
1 | J:200985 Cai EP, Wu X, Schroer SA, Elia AJ, Nostro MC, Zacksenhaus E, Woo M, Retinoblastoma tumor suppressor protein in pancreatic progenitors controls alpha- and beta-cell fate. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14723-8 |
1 | J:129103 Chao CS, Loomis ZL, Lee JE, Sussel L, Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells. Dev Biol. 2007 Dec 15;312(2):523-32 |
1 | J:278248 Chen C, Shiota C, Agostinelli G, Ridley D, Jiang Y, Ma J, Prasadan K, Xiao X, Gittes GK, Evidence of a developmental origin for beta-cell heterogeneity using a dual lineage-tracing technology. Development. 2019 Jun 27;146(13):dev164913 |
1 | J:105207 Chu K, Tsai MJ, Neuronatin, a downstream target of BETA2/NeuroD1 in the pancreas, is involved in glucose-mediated insulin secretion. Diabetes. 2005 Apr;54(4):1064-73 |
1 | J:337474 Cobo I, Paliwal S, Bodas C, Felipe I, Melia-Aloma J, Torres A, Martinez-Villarreal J, Malumbres M, Garcia F, Millan I, Del Pozo N, Park JC, MacDonald RJ, Munoz J, Mendez R, Real FX, NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation. Nat Commun. 2023 Jun 23;14(1):3761 |
2 | J:220324 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C, Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 1;142(5):871-82 |
1 | J:209744 Diaferia GR, Cirulli V, Biunno I, SEL1L regulates adhesion, proliferation and secretion of insulin by affecting integrin signaling. PLoS One. 2013;8(11):e79458 |
1 | J:104222 Fazio EN, Everest M, Colman R, Wang R, Pin CL, Altered Glut-2 accumulation and beta-cell function in mice lacking the exocrine-specific transcription factor, Mist1. J Endocrinol. 2005 Dec;187(3):407-18 |
1 | J:141158 Fontaniere S, Duvillie B, Scharfmann R, Carreira C, Wang ZQ, Zhang CX, Tumour suppressor menin is essential for development of the pancreatic endocrine cells. J Endocrinol. 2008 Nov;199(2):287-98 |
1 | J:192856 George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE, Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol. 2012 Dec;32(24):5116-28 |
2* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1 | J:134078 Hezel AF, Gurumurthy S, Granot Z, Swisa A, Chu GC, Bailey G, Dor Y, Bardeesy N, Depinho RA, Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. Mol Cell Biol. 2008 Apr;28(7):2414-25 |
1 | J:275470 Hirata K, Kodama S, Nakano Y, Minaki-Nakagawa Y, Aoyama Y, Sakikubo M, Goto T, Yoshida M, Masui T, Yamamoto T, Uemoto S, Kawaguchi Y, Exocrine tissue-driven TFF2 prevents apoptotic cell death of endocrine lineage during pancreas organogenesis. Sci Rep. 2019 Feb 7;9(1):1636 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1 | J:154990 Kang HS, Kim YS, ZeRuth G, Beak JY, Gerrish K, Kilic G, Sosa-Pineda B, Jensen J, Foley J, Jetten AM, Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression. Mol Cell Biol. 2009 Dec;29(24):6366-79 |
2 | J:257425 Kim DS, Song L, Wang J, Wu H, Gu G, Sugi Y, Li Z, Wang H, GRP94 Is an Essential Regulator of Pancreatic beta-Cell Development, Mass, and Function in Male Mice. Endocrinology. 2018 Feb 1;159(2):1062-1073 |
1 | J:112755 Kim HJ, Schleiffarth JR, Jessurun J, Sumanas S, Petryk A, Lin S, Ekker SC, Wnt5 signaling in vertebrate pancreas development. BMC Biol. 2005;3:23 |
1 | J:306907 Kodani N, Nakae J, Kobayashi M, Kikuchi O, Kitamura T, Itoh H, FCoR-Foxo1 Axis Regulates alpha-Cell Mass through Repression of Arx Expression. iScience. 2020 Jan 24;23(1):100798 |
1 | J:272578 Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G, Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. Dev Cell. 2019 Jan 7;48(1):49-63.e7 |
2 | J:290417 Lorberbaum DS, Kishore S, Rosselot C, Sarbaugh D, Brooks EP, Aragon E, Xuan S, Simon O, Ghosh D, Mendelsohn C, Gadue P, Sussel L, Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human beta cell specification. Development. 2020 Jun 22;147(12):dev189977 |
1 | J:63347 Maldonado TS, Kadison AS, Crisera CA, Grau JB, Alkasab SL, Longaker MT, Gittes GK, Ontogeny of activin B and follistatin in developing embryonic mouse pancreas: implications for lineage selection. J Gastrointest Surg. 2000 May-Jun;4(3):269-75 |
1 | J:227268 Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Bjorklund P, Mackie K, Di Marzo V, Hokfelt TG, Dobrzyn A, Harkany T, Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6185-94 |
2 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
1* | J:190429 Nieto M, Hevia P, Garcia E, Klein D, Alvarez-Cubela S, Bravo-Egana V, Rosero S, Damaris Molano R, Vargas N, Ricordi C, Pileggi A, Diez J, Dominguez-Bendala J, Pastori RL, Antisense miR-7 impairs insulin expression in developing pancreas and in cultured pancreatic buds. Cell Transplant. 2012;21(8):1761-74 |
1 | J:253982 Norlin S, Parekh V, Edlund H, The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival. Development. 2018 Jan 3;145(1):dev154468 |
1 | J:284168 Nyeng P, Heilmann S, Lof-Ohlin ZM, Pettersson NF, Hermann FM, Reynolds AB, Semb H, p120ctn-Mediated Organ Patterning Precedes and Determines Pancreatic Progenitor Fate. Dev Cell. 2019 Apr 8;49(1):31-47.e9 |
1* | J:32017 Offield MF, Jetton TL, Labosky PA, Ray M, Stein RW, Magnuson MA, Hogan BL, Wright CV, PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development. 1996 Mar;122(3):983-95 |
2 | J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461 |
1 | J:239946 Pan FC, Brissova M, Powers AC, Pfaff S, Wright CV, Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing beta-cells to a delta-like fate and reveals a facultative proliferative capacity in aged beta-cells. Development. 2015 Nov 01;142(21):3637-48 |
1 | J:335234 Parveen N, Wang JK, Bhattacharya S, Cuala J, Singh Rajkumar M, Butler AE, Wu X, Shih HP, Georgia SK, Dhawan S, DNA methylation Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic beta-cell Heterogeneity. Diabetes. 2023 Jan 6;72(5):575-89 |
1 | J:246400 Paul L, Walker EM, Drosos Y, Cyphert HA, Neale G, Stein R, South J, Grosveld G, Herrera PL, Sosa-Pineda B, Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine beta-Cells. Diabetes. 2016 Mar;65(3):687-98 |
1 | J:208409 Reinert RB, Cai Q, Hong JY, Plank JL, Aamodt K, Prasad N, Aramandla R, Dai C, Levy SE, Pozzi A, Labosky PA, Wright CV, Brissova M, Powers AC, Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding. Development. 2014 Apr;141(7):1480-91 |
1 | J:65594 Sander M, Sussel L, Conners J, Scheel D, Kalamaras J, Dela Cruz F, Schwitzgebel V, Hayes-Jordan A, German M, Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas. Development. 2000 Dec;127(24):5533-40 |
1 | J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356 |
2 | J:361603 Scavuzzo MA, Szlachcic WJ, Hill MC, Ziojla NM, Teaw J, Carlson JC, Tiessen J, Chmielowiec J, Martin JF, Borowiak M, Pancreatic organogenesis mapped through space and time. Exp Mol Med. 2025 Feb;57(1):204-220 |
1 | J:182209 Schulz C, Gomez Perdiguero E, Chorro L, Szabo-Rogers H, Cagnard N, Kierdorf K, Prinz M, Wu B, Jacobsen SE, Pollard JW, Frampton J, Liu KJ, Geissmann F, A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science. 2012 Apr 6;336(6077):86-90 |
1 | J:243381 Serafimidis I, Rodriguez-Aznar E, Lesche M, Yoshioka K, Takuwa Y, Dahl A, Pan D, Gavalas A, Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. PLoS Biol. 2017 Mar;15(3):e2000949 |
1 | J:141017 Seymour PA, Freude KK, Dubois CL, Shih HP, Patel NA, Sander M, A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation. Dev Biol. 2008 Nov 1;323(1):19-30 |
2 | J:338071 Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn LJ, Rosenthal B, Gurtler M, Estanboulieh RR, Shvartsman D, Gifford DK, Trapnell C, Melton D, A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets. Cell. 2019 Feb 7;176(4):790-804.e13 |
1* | J:218695 Soggia A, Ramond C, Akiyama H, Scharfmann R, Duvillie B, von Hippel-Lindau gene disruption in mouse pancreatic progenitors and its consequences on endocrine differentiation in vivo: importance of HIF1-alpha and VEGF-A upregulation. Diabetologia. 2014 Nov;57(11):2348-56 |
1 | J:151981 Spence JR, Lange AW, Lin SC, Kaestner KH, Lowy AM, Kim I, Whitsett JA, Wells JM, Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell. 2009 Jul;17(1):62-74 |
1* | J:87397 Sumazaki R, Shiojiri N, Isoyama S, Masu M, Keino-Masu K, Osawa M, Nakauchi H, Kageyama R, Matsui A, Conversion of biliary system to pancreatic tissue in Hes1-deficient mice. Nat Genet. 2004 Jan;36(1):83-7 |
1 | J:147764 Svensson P, Bergqvist I, Norlin S, Edlund H, MFng is dispensable for mouse pancreas development and function. Mol Cell Biol. 2009 Apr;29(8):2129-38 |
1 | J:186391 Tao J, Zhu M, Wang H, Afelik S, Vasievich MP, Chen XW, Zhu G, Jensen J, Ginsburg D, Zhang B, SEC23B is required for the maintenance of murine professional secretory tissues. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):E2001-9 |
1 | J:307817 Theis A, Singer RA, Garofalo D, Paul A, Narayana A, Sussel L, Groucho co-repressor proteins regulate beta cell development and proliferation by repressing Foxa1 in the developing mouse pancreas. Development. 2021 Mar 24;148(6):dev192401 |
1 | J:208719 Tsai MJ, Yang-Yen HF, Chiang MK, Wang MJ, Wu SS, Chen SH, TCTP is essential for beta-cell proliferation and mass expansion during development and beta-cell adaptation in response to insulin resistance. Endocrinology. 2014 Feb;155(2):392-404 |
1 | J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521 |
1 | J:225743 Um SH, Sticker-Jantscheff M, Chau GC, Vintersten K, Mueller M, Gangloff YG, Adams RH, Spetz JF, Elghazi L, Pfluger PT, Pende M, Bernal-Mizrachi E, Tauler A, Tschop MH, Thomas G, Kozma SC, S6K1 controls pancreatic beta cell size independently of intrauterine growth restriction. J Clin Invest. 2015 Jul 1;125(7):2736-47 |
1 | J:364195 Yang L, Yu XX, Wang X, Jin CT, Xu CR, The expression order determines the pioneer functions of NGN3 and NEUROD1 in pancreatic endocrine differentiation. Sci Adv. 2025 Mar 28;11(13):eadt4770 |
1 | J:174673 Yang YP, Thorel F, Boyer DF, Herrera PL, Wright CV, Context-specific {alpha}-to-{beta}-cell reprogramming by forced Pdx1 expression. Genes Dev. 2011 Aug 15;25(16):1680-5 |
1 | J:107205 Yevtodiyenko A, Schmidt JV, Dlk1 expression marks developing endothelium and sites of branching morphogenesis in the mouse embryo and placenta. Dev Dyn. 2006 Apr;235(4):1115-23 |
1 | J:280702 Yung T, Poon F, Liang M, Coquenlorge S, McGaugh EC, Hui CC, Wilson MD, Nostro MC, Kim TH, Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals. Nat Commun. 2019 Oct 11;10(1):4647 |
2 | J:144661 Zhang W, Feng D, Li Y, Iida K, McGrath B, Cavener DR, PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis. Cell Metab. 2006 Dec;4(6):491-7 |
Ins2 insulin II (Synonyms: Ins-2, InsII, Mody, Mody4) | |
Results | Reference |
1 | J:219809 Afelik S, Pool B, Schmerr M, Penton C, Jensen J, Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development. Dev Biol. 2015 Mar 15;399(2):204-17 |
1 | J:70719 Allen-Jennings AE, Hartman MG, Kociba GJ, Hai T, The roles of atf3 in glucose homeostasis. a transgenic mouse model with liver dysfunction and defects in endocrine pancreas. J Biol Chem. 2001 Aug 3;276(31):29507-14 |
2 | J:156329 Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L, Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. J Biol Chem. 2009 Nov 6;284(45):31236-48 |
1 | J:305792 Ansarullah, Jain C, Far FF, Homberg S, Wissmiller K, von Hahn FG, Raducanu A, Schirge S, Sterr M, Bilekova S, Siehler J, Wiener J, Oppenlander L, Morshedi A, Bastidas-Ponce A, Collden G, Irmler M, Beckers J, Feuchtinger A, Grzybek M, Ahlbrecht C, Feederle R, Plettenburg O, Muller TD, Meier M, Tschop MH, Coskun U, Lickert H, Inceptor counteracts insulin signalling in beta-cells to control glycaemia. Nature. 2021 Feb;590(7845):326-331 |
1 | J:119565 Boyer DF, Fujitani Y, Gannon M, Powers AC, Stein RW, Wright CV, Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression. Dev Biol. 2006 Oct 15;298(2):616-31 |
1 | J:116552 Brissova M, Shostak A, Shiota M, Wiebe PO, Poffenberger G, Kantz J, Chen Z, Carr C, Jerome WG, Chen J, Baldwin HS, Nicholson W, Bader DM, Jetton T, Gannon M, Powers AC, Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function. Diabetes. 2006 Nov;55(11):2974-85 |
1 | J:255164 Broche B, Ben Fradj S, Aguilar E, Sancerni T, Benard M, Makaci F, Berthault C, Scharfmann R, Alves-Guerra MC, Duvillie B, Mitochondrial Protein UCP2 Controls Pancreas Development. Diabetes. 2018 Jan;67(1):78-84 |
1 | J:200985 Cai EP, Wu X, Schroer SA, Elia AJ, Nostro MC, Zacksenhaus E, Woo M, Retinoblastoma tumor suppressor protein in pancreatic progenitors controls alpha- and beta-cell fate. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14723-8 |
1 | J:129103 Chao CS, Loomis ZL, Lee JE, Sussel L, Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells. Dev Biol. 2007 Dec 15;312(2):523-32 |
1 | J:278248 Chen C, Shiota C, Agostinelli G, Ridley D, Jiang Y, Ma J, Prasadan K, Xiao X, Gittes GK, Evidence of a developmental origin for beta-cell heterogeneity using a dual lineage-tracing technology. Development. 2019 Jun 27;146(13):dev164913 |
1 | J:105207 Chu K, Tsai MJ, Neuronatin, a downstream target of BETA2/NeuroD1 in the pancreas, is involved in glucose-mediated insulin secretion. Diabetes. 2005 Apr;54(4):1064-73 |
2 | J:220324 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C, Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 1;142(5):871-82 |
1 | J:209744 Diaferia GR, Cirulli V, Biunno I, SEL1L regulates adhesion, proliferation and secretion of insulin by affecting integrin signaling. PLoS One. 2013;8(11):e79458 |
1 | J:119914 Doyle MJ, Loomis ZL, Sussel L, Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet. Development. 2007 Feb;134(3):515-23 |
1 | J:104222 Fazio EN, Everest M, Colman R, Wang R, Pin CL, Altered Glut-2 accumulation and beta-cell function in mice lacking the exocrine-specific transcription factor, Mist1. J Endocrinol. 2005 Dec;187(3):407-18 |
1 | J:141158 Fontaniere S, Duvillie B, Scharfmann R, Carreira C, Wang ZQ, Zhang CX, Tumour suppressor menin is essential for development of the pancreatic endocrine cells. J Endocrinol. 2008 Nov;199(2):287-98 |
1 | J:192856 George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE, Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol. 2012 Dec;32(24):5116-28 |
2* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1 | J:134078 Hezel AF, Gurumurthy S, Granot Z, Swisa A, Chu GC, Bailey G, Dor Y, Bardeesy N, Depinho RA, Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. Mol Cell Biol. 2008 Apr;28(7):2414-25 |
1 | J:275470 Hirata K, Kodama S, Nakano Y, Minaki-Nakagawa Y, Aoyama Y, Sakikubo M, Goto T, Yoshida M, Masui T, Yamamoto T, Uemoto S, Kawaguchi Y, Exocrine tissue-driven TFF2 prevents apoptotic cell death of endocrine lineage during pancreas organogenesis. Sci Rep. 2019 Feb 7;9(1):1636 |
2* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1 | J:154990 Kang HS, Kim YS, ZeRuth G, Beak JY, Gerrish K, Kilic G, Sosa-Pineda B, Jensen J, Foley J, Jetten AM, Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression. Mol Cell Biol. 2009 Dec;29(24):6366-79 |
2 | J:257425 Kim DS, Song L, Wang J, Wu H, Gu G, Sugi Y, Li Z, Wang H, GRP94 Is an Essential Regulator of Pancreatic beta-Cell Development, Mass, and Function in Male Mice. Endocrinology. 2018 Feb 1;159(2):1062-1073 |
1 | J:112755 Kim HJ, Schleiffarth JR, Jessurun J, Sumanas S, Petryk A, Lin S, Ekker SC, Wnt5 signaling in vertebrate pancreas development. BMC Biol. 2005;3:23 |
1 | J:306907 Kodani N, Nakae J, Kobayashi M, Kikuchi O, Kitamura T, Itoh H, FCoR-Foxo1 Axis Regulates alpha-Cell Mass through Repression of Arx Expression. iScience. 2020 Jan 24;23(1):100798 |
1 | J:272578 Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G, Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. Dev Cell. 2019 Jan 7;48(1):49-63.e7 |
2 | J:290417 Lorberbaum DS, Kishore S, Rosselot C, Sarbaugh D, Brooks EP, Aragon E, Xuan S, Simon O, Ghosh D, Mendelsohn C, Gadue P, Sussel L, Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human beta cell specification. Development. 2020 Jun 22;147(12):dev189977 |
1 | J:63347 Maldonado TS, Kadison AS, Crisera CA, Grau JB, Alkasab SL, Longaker MT, Gittes GK, Ontogeny of activin B and follistatin in developing embryonic mouse pancreas: implications for lineage selection. J Gastrointest Surg. 2000 May-Jun;4(3):269-75 |
1 | J:227268 Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Bjorklund P, Mackie K, Di Marzo V, Hokfelt TG, Dobrzyn A, Harkany T, Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6185-94 |
1* | J:199085 Martinez-Campos E, Hernandez-Sanmiguel E, Lopez-Sanchez C, De Pablo F, Hernandez-Sanchez C, Alternative splicing variants of proinsulin mRNA and the effects of excess proinsulin on cardiac morphogenesis. FEBS Lett. 2013 Jul 11;587(14):2272-7 |
2 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
1 | J:253982 Norlin S, Parekh V, Edlund H, The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival. Development. 2018 Jan 3;145(1):dev154468 |
1 | J:284168 Nyeng P, Heilmann S, Lof-Ohlin ZM, Pettersson NF, Hermann FM, Reynolds AB, Semb H, p120ctn-Mediated Organ Patterning Precedes and Determines Pancreatic Progenitor Fate. Dev Cell. 2019 Apr 8;49(1):31-47.e9 |
1* | J:32017 Offield MF, Jetton TL, Labosky PA, Ray M, Stein RW, Magnuson MA, Hogan BL, Wright CV, PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development. 1996 Mar;122(3):983-95 |
2 | J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461 |
1 | J:239946 Pan FC, Brissova M, Powers AC, Pfaff S, Wright CV, Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing beta-cells to a delta-like fate and reveals a facultative proliferative capacity in aged beta-cells. Development. 2015 Nov 01;142(21):3637-48 |
1 | J:335234 Parveen N, Wang JK, Bhattacharya S, Cuala J, Singh Rajkumar M, Butler AE, Wu X, Shih HP, Georgia SK, Dhawan S, DNA methylation Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic beta-cell Heterogeneity. Diabetes. 2023 Jan 6;72(5):575-89 |
1 | J:246400 Paul L, Walker EM, Drosos Y, Cyphert HA, Neale G, Stein R, South J, Grosveld G, Herrera PL, Sosa-Pineda B, Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine beta-Cells. Diabetes. 2016 Mar;65(3):687-98 |
1 | J:208409 Reinert RB, Cai Q, Hong JY, Plank JL, Aamodt K, Prasad N, Aramandla R, Dai C, Levy SE, Pozzi A, Labosky PA, Wright CV, Brissova M, Powers AC, Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding. Development. 2014 Apr;141(7):1480-91 |
1 | J:65594 Sander M, Sussel L, Conners J, Scheel D, Kalamaras J, Dela Cruz F, Schwitzgebel V, Hayes-Jordan A, German M, Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas. Development. 2000 Dec;127(24):5533-40 |
1 | J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356 |
2 | J:361603 Scavuzzo MA, Szlachcic WJ, Hill MC, Ziojla NM, Teaw J, Carlson JC, Tiessen J, Chmielowiec J, Martin JF, Borowiak M, Pancreatic organogenesis mapped through space and time. Exp Mol Med. 2025 Feb;57(1):204-220 |
1 | J:182209 Schulz C, Gomez Perdiguero E, Chorro L, Szabo-Rogers H, Cagnard N, Kierdorf K, Prinz M, Wu B, Jacobsen SE, Pollard JW, Frampton J, Liu KJ, Geissmann F, A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science. 2012 Apr 6;336(6077):86-90 |
1 | J:243381 Serafimidis I, Rodriguez-Aznar E, Lesche M, Yoshioka K, Takuwa Y, Dahl A, Pan D, Gavalas A, Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. PLoS Biol. 2017 Mar;15(3):e2000949 |
1 | J:141017 Seymour PA, Freude KK, Dubois CL, Shih HP, Patel NA, Sander M, A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation. Dev Biol. 2008 Nov 1;323(1):19-30 |
2 | J:338071 Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn LJ, Rosenthal B, Gurtler M, Estanboulieh RR, Shvartsman D, Gifford DK, Trapnell C, Melton D, A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets. Cell. 2019 Feb 7;176(4):790-804.e13 |
1 | J:151981 Spence JR, Lange AW, Lin SC, Kaestner KH, Lowy AM, Kim I, Whitsett JA, Wells JM, Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell. 2009 Jul;17(1):62-74 |
1* | J:87397 Sumazaki R, Shiojiri N, Isoyama S, Masu M, Keino-Masu K, Osawa M, Nakauchi H, Kageyama R, Matsui A, Conversion of biliary system to pancreatic tissue in Hes1-deficient mice. Nat Genet. 2004 Jan;36(1):83-7 |
1 | J:147764 Svensson P, Bergqvist I, Norlin S, Edlund H, MFng is dispensable for mouse pancreas development and function. Mol Cell Biol. 2009 Apr;29(8):2129-38 |
1 | J:186391 Tao J, Zhu M, Wang H, Afelik S, Vasievich MP, Chen XW, Zhu G, Jensen J, Ginsburg D, Zhang B, SEC23B is required for the maintenance of murine professional secretory tissues. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):E2001-9 |
2 | J:307817 Theis A, Singer RA, Garofalo D, Paul A, Narayana A, Sussel L, Groucho co-repressor proteins regulate beta cell development and proliferation by repressing Foxa1 in the developing mouse pancreas. Development. 2021 Mar 24;148(6):dev192401 |
1 | J:208719 Tsai MJ, Yang-Yen HF, Chiang MK, Wang MJ, Wu SS, Chen SH, TCTP is essential for beta-cell proliferation and mass expansion during development and beta-cell adaptation in response to insulin resistance. Endocrinology. 2014 Feb;155(2):392-404 |
1 | J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521 |
1 | J:225743 Um SH, Sticker-Jantscheff M, Chau GC, Vintersten K, Mueller M, Gangloff YG, Adams RH, Spetz JF, Elghazi L, Pfluger PT, Pende M, Bernal-Mizrachi E, Tauler A, Tschop MH, Thomas G, Kozma SC, S6K1 controls pancreatic beta cell size independently of intrauterine growth restriction. J Clin Invest. 2015 Jul 1;125(7):2736-47 |
1 | J:364195 Yang L, Yu XX, Wang X, Jin CT, Xu CR, The expression order determines the pioneer functions of NGN3 and NEUROD1 in pancreatic endocrine differentiation. Sci Adv. 2025 Mar 28;11(13):eadt4770 |
1 | J:174673 Yang YP, Thorel F, Boyer DF, Herrera PL, Wright CV, Context-specific {alpha}-to-{beta}-cell reprogramming by forced Pdx1 expression. Genes Dev. 2011 Aug 15;25(16):1680-5 |
1 | J:107205 Yevtodiyenko A, Schmidt JV, Dlk1 expression marks developing endothelium and sites of branching morphogenesis in the mouse embryo and placenta. Dev Dyn. 2006 Apr;235(4):1115-23 |
1 | J:280702 Yung T, Poon F, Liang M, Coquenlorge S, McGaugh EC, Hui CC, Wilson MD, Nostro MC, Kim TH, Sufu- and Spop-mediated downregulation of Hedgehog signaling promotes beta cell differentiation through organ-specific niche signals. Nat Commun. 2019 Oct 11;10(1):4647 |
2 | J:144661 Zhang W, Feng D, Li Y, Iida K, McGrath B, Cavener DR, PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis. Cell Metab. 2006 Dec;4(6):491-7 |
Insc INSC spindle orientation adaptor protein (Synonyms: 3830422K02Rik, Inscuteable) | |
Results | Reference |
1 | J:237485 Harris L, Zalucki O, Gobius I, McDonald H, Osinki J, Harvey TJ, Essebier A, Vidovic D, Gladwyn-Ng I, Burne TH, Heng JI, Richards LJ, Gronostajski RM, Piper M, Transcriptional regulation of intermediate progenitor cell generation during hippocampal development. Development. 2016 Dec 15;143(24):4620-4630 |
Insig1 insulin induced gene 1 (Synonyms: 1810013C12Rik, Insig-1) | |
Results | Reference |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
1 | J:264124 Tsushima H, Tang YJ, Puviindran V, Hsu SC, Nadesan P, Yu C, Zhang H, Mirando AJ, Hilton MJ, Alman BA, Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis. Development. 2018 Jul 9;145(13):dev162396 |
Insl3 insulin-like 3 (Synonyms: Ley I-L, Rlf, Rlnl) | |
Results | Reference |
1 | J:147876 Barsoum IB, Bingham NC, Parker KL, Jorgensen JS, Yao HH, Activation of the Hedgehog pathway in the mouse fetal ovary leads to ectopic appearance of fetal Leydig cells and female pseudohermaphroditism. Dev Biol. 2009 May 1;329(1):96-103 |
1* | J:60198 Emmen JM, McLuskey A, Adham IM, Engel W, Verhoef-Post M, Themmen AP, Grootegoed JA, Brinkmann AO, Involvement of insulin-like factor 3 (Insl3) in diethylstilbestrol-induced cryptorchidism. Endocrinology. 2000 Feb;141(2):846-9 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1 | J:55881 Nef S, Parada LF, Cryptorchidism in mice mutant for Insl3. Nat Genet. 1999 Jul;22(3):295-9 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
2* | J:39635 Zimmermann S, Schottler P, Engel W, Adham IM, Mouse Leydig insulin-like (Ley I-L) gene: structure and expression during testis and ovary development. Mol Reprod Dev. 1997 May;47(1):30-8 |
Insm1 insulinoma-associated 1 (Synonyms: IA-1) | |
Results | Reference |
1 | J:144651 Farkas LM, Haffner C, Giger T, Khaitovich P, Nowick K, Birchmeier C, Paabo S, Huttner WB, Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex. Neuron. 2008 Oct 9;60(1):40-55 |
1 | J:217584 Gerstmann K, Pensold D, Symmank J, Khundadze M, Hubner CA, Bolz J, Zimmer G, Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions. Development. 2015 Jan 1;142(1):140-50 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
2* | J:228519 Jia S, Wildner H, Birchmeier C, Insm1 controls the differentiation of pulmonary neuroendocrine cells by repressing Hes1. Dev Biol. 2015 Dec 1;408(1):90-8 |
1 | J:336865 Li S, He S, Lu Y, Jia S, Liu Z, Epistatic genetic interactions between Insm1 and Ikzf2 during cochlear outer hair cell development. Cell Rep. 2023 May 30;42(5):112504 |
2 | J:239944 Lorenzen SM, Duggan A, Osipovich AB, Magnuson MA, Garcia-Anoveros J, Insm1 promotes neurogenic proliferation in delaminated otic progenitors. Mech Dev. 2015 Nov;138 Pt 3:233-45 |
2 | J:214095 Osipovich AB, Long Q, Manduchi E, Gangula R, Hipkens SB, Schneider J, Okubo T, Stoeckert CJ Jr, Takada S, Magnuson MA, Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3. Development. 2014 Aug;141(15):2939-49 |
1 | J:220958 Rosenthal EH, Tonchev AB, Stoykova A, Chowdhury K, Regulation of archicortical arealization by the transcription factor Zbtb20. Hippocampus. 2012 Nov;22(11):2144-56 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:130853 Wildner H, Gierl MS, Strehle M, Pla P, Birchmeier C, Insm1 (IA-1) is a crucial component of the transcriptional network that controls differentiation of the sympatho-adrenal lineage. Development. 2008 Feb;135(3):473-81 |
2 | J:267715 Wiwatpanit T, Lorenzen SM, Cantu JA, Foo CZ, Hogan AK, Marquez F, Clancy JC, Schipma MJ, Cheatham MA, Duggan A, Garcia-Anoveros J, Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1. Nature. 2018 Nov;563(7733):691-695 |
1* | J:77887 Xie J, Cai T, Zhang H, Lan MS, Notkins AL, The Zinc-Finger Transcription Factor INSM1 Is Expressed during Embryo Development and Interacts with the Cbl-Associated Protein. Genomics. 2002 Jul;80(1):54-61 |
Insm2 insulinoma-associated 2 (Synonyms: mlt 1) | |
Results | Reference |
1* | J:173856 Cai T, Chen X, Wang R, Xu H, You Y, Zhang T, Lan MS, Notkins AL, Expression of insulinoma-associated 2 (INSM2) in pancreatic islet cells is regulated by the transcription factors Ngn3 and NeuroD1. Endocrinology. 2011 May;152(5):1961-9 |
Insr insulin receptor (Synonyms: 4932439J01Rik, CD220, D630014A15Rik, IR, IR-A, IR-B) | |
Results | Reference |
1 | J:326523 Kheirollahi V, Khadim A, Kiliaris G, Korfei M, Barroso MM, Alexopoulos I, Vazquez-Armendariz AI, Wygrecka M, Ruppert C, Guenther A, Seeger W, Herold S, El Agha E, Transcriptional Profiling of Insulin-like Growth Factor Signaling Components in Embryonic Lung Development and Idiopathic Pulmonary Fibrosis. Cells. 2022 Jun 20;11(12) |
1 | J:241923 Lopez IP, Pineiro-Hermida S, Pais RS, Torrens R, Hoeflich A, Pichel JG, Involvement of Igf1r in Bronchiolar Epithelial Regeneration: Role during Repair Kinetics after Selective Club Cell Ablation. PLoS One. 2016;11(11):e0166388 |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
Ints5 integrator complex subunit 5 (Synonyms: 1110055N21Rik, mKIAA1698) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Ints6 integrator complex subunit 6 (Synonyms: 2900075H24Rik, Ddx26, DICE1, Notch2l) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Invs inversin | |
Results | Reference |
1 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
Ipo5 importin 5 (Synonyms: 1110011C18Rik, 5730478E03Rik, IMB3, importin beta 3, Kpnb3, RanBP5) | |
Results | Reference |
2* | J:123290 Hogarth CA, Jans DA, Loveland KL, Subcellular distribution of importins correlates with germ cell maturation. Dev Dyn. 2007 Aug;236(8):2311-20 |
Ipo13 importin 13 (Synonyms: Imp13, Kap13) | |
Results | Reference |
1* | J:129949 Cui CY, Kunisada M, Esibizione D, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet. 2007 Nov 1;16(21):2583-90 |
Iqcg IQ motif containing G (Synonyms: 2400003L07Rik, esgd12d, G1-374-12, repro1, stubby12d) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Irf4 interferon regulatory factor 4 (Synonyms: IRF-4, Spip) | |
Results | Reference |
1* | J:225352 Wang S, He Q, Ma D, Xue Y, Liu F, Irf4 Regulates the Choice between T Lymphoid-Primed Progenitor and Myeloid Lineage Fates during Embryogenesis. Dev Cell. 2015 Sep 28;34(6):621-31 |
Irf6 interferon regulatory factor 6 (Synonyms: E230028I05Rik) | |
Results | Reference |
1 | J:226941 Akerberg BN, Sarangam ML, Stankunas K, Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Dev Biol. 2015 Nov 1;407(1):158-72 |
1* | J:299515 Bezamat M, Souza JF, Silva FMF, Correa EG, Fatturi AL, Brancher JA, Carvalho FM, Cavallari T, Bertolazo L, Machado-Souza C, Koruyucu M, Bayram M, Racic A, Harrison BM, Sweat YY, Letra A, Studen-Pavlovich D, Seymen F, Amendt B, Werneck RI, Costa MC, Modesto A, Vieira AR, Gene-environment interaction in molar-incisor hypomineralization. PLoS One. 2021;16(1):e0241898 |
1 | J:234343 Kawasaki M, Kawasaki K, Oommen S, Blackburn J, Watanabe M, Nagai T, Kitamura A, Maeda T, Liu B, Schmidt-Ullrich R, Akiyama T, Inoue J, Hammond NL, Sharpe PT, Ohazama A, Regional regulation of Filiform tongue papillae development by Ikkalpha/Irf6. Dev Dyn. 2016 Sep;245(9):937-46 |
1* | J:301228 Laugel-Haushalter V, Langer A, Marrie J, Fraulob V, Schuhbaur B, Koch-Phillips M, Dolle P, Bloch-Zupan A, From the transcription of genes involved in ectodermal dysplasias to the understanding of associated dental anomalies. Mol Syndromol. 2012 Oct;3(4):158-68 |
2 | J:161645 Moretti F, Marinari B, Lo Iacono N, Botti E, Giunta A, Spallone G, Garaffo G, Vernersson-Lindahl E, Merlo G, Mills AA, Ballaro C, Alema S, Chimenti S, Guerrini L, Costanzo A, A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias. J Clin Invest. 2010 May 3;120(5):1570-7 |
1* | J:273627 Thompson J, Mendoza F, Tan E, Bertol JW, Gaggar AS, Jun G, Biguetti C, Fakhouri WD, A cleft lip and palate gene, Irf6, is involved in osteoblast differentiation of craniofacial bone. Dev Dyn. 2019 Mar;248(3):221-232 |
Irs4 insulin receptor substrate 4 (Synonyms: IRS-4) | |
Results | Reference |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Irx1 Iroquois homeobox 1 | |
Results | Reference |
1 | J:307093 Amato CM, Yao HH, Developmental and sexual dimorphic atlas of the prenatal mouse external genitalia at the single-cell level. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2103856118 |
1* | J:61328 Cohen DR, Cheng CW, Cheng SH, Hui C, Expression of two novel mouse iroquois homeobox genes during neurogenesis. Mech Dev. 2000 Mar 1;91(1-2):317-21 |
1 | J:272612 Eyal S, Rubin S, Krief S, Levin L, Zelzer E, Common cellular origin and diverging developmental programs for different sesamoid bones. Development. 2019 Feb 28;146(4):dev167452 |
2 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
Irx2 Iroquois homeobox 2 (Synonyms: IRX6) | |
Results | Reference |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1 | J:129103 Chao CS, Loomis ZL, Lee JE, Sussel L, Genetic identification of a novel NeuroD1 function in the early differentiation of islet alpha, PP and epsilon cells. Dev Biol. 2007 Dec 15;312(2):523-32 |
1* | J:61328 Cohen DR, Cheng CW, Cheng SH, Hui C, Expression of two novel mouse iroquois homeobox genes during neurogenesis. Mech Dev. 2000 Mar 1;91(1-2):317-21 |
2 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
Irx3 Iroquois related homeobox 3 | |
Results | Reference |
1* | J:61328 Cohen DR, Cheng CW, Cheng SH, Hui C, Expression of two novel mouse iroquois homeobox genes during neurogenesis. Mech Dev. 2000 Mar 1;91(1-2):317-21 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1 | J:265538 Fu A, Oberholtzer SM, Bagheri-Fam S, Rastetter RH, Holdreith C, Caceres VL, John SV, Shaw SA, Krentz KJ, Zhang X, Hui CC, Wilhelm D, Jorgensen JS, Dynamic expression patterns of Irx3 and Irx5 during germline nest breakdown and primordial follicle formation promote follicle survival in mouse ovaries. PLoS Genet. 2018 Aug;14(8):e1007488 |
1 | J:355142 Gomez-Del Arco P, Isern J, Jimenez-Carretero D, Lopez-Maderuelo D, Pineiro-Sabaris R, El Abdellaoui-Soussi F, Torroja C, Vera-Pedrosa ML, Grima-Terren M, Benguria A, Simon-Chica A, Queiro-Palou A, Dopazo A, Sanchez-Cabo F, Jalife J, de la Pompa JL, Filgueiras-Rama D, Munoz-Canoves P, Redondo JM, The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development. Nat Commun. 2024 Oct 4;15(1):8602 |
1 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:158526 Naillat F, Prunskaite-Hyyrylainen R, Pietila I, Sormunen R, Jokela T, Shan J, Vainio SJ, Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development. Hum Mol Genet. 2010 Apr 15;19(8):1539-50 |
1 | J:175992 Zhang SS, Kim KH, Rosen A, Smyth JW, Sakuma R, Delgado-Olguin P, Davis M, Chi NC, Puviindran V, Gaborit N, Sukonnik T, Wylie JN, Brand-Arzamendi K, Farman GP, Kim J, Rose RA, Marsden PA, Zhu Y, Zhou YQ, Miquerol L, Henkelman RM, Stainier DY, Shaw RM, HuiCC, Bruneau BG, Backx PH, Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network. Proc Natl Acad Sci U S A. 2011 Aug 16;108(33):13576-81 |
Irx4 Iroquois homeobox 4 | |
Results | Reference |
1 | J:332132 Cattaneo P, Hayes MGB, Baumgarten N, Hecker D, Peruzzo S, Aslan GS, Kunderfranco P, Larcher V, Zhang L, Contu R, Fonseca G, Spinozzi S, Chen J, Condorelli G, Dimmeler S, Schulz MH, Heinz S, Guimaraes-Camboa N, Evans SM, DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal. Nat Commun. 2022 Dec 2;13(1):7444 |
Irx5 Iroquois homeobox 5 | |
Results | Reference |
1 | J:103461 Cheng CW, Chow RL, Lebel M, Sakuma R, Cheung HO, Thanabalasingham V, Zhang X, Bruneau BG, Birch DG, Hui CC, McInnes RR, Cheng SH, The Iroquois homeobox gene, Irx5, is required for retinal cone bipolar cell development. Dev Biol. 2005 Nov 1;287(1):48-60 |
1* | J:61328 Cohen DR, Cheng CW, Cheng SH, Hui C, Expression of two novel mouse iroquois homeobox genes during neurogenesis. Mech Dev. 2000 Mar 1;91(1-2):317-21 |
1 | J:115194 Costantini DL, Arruda EP, Agarwal P, Kim KH, Zhu Y, Zhu W, Lebel M, Cheng CW, Park CY, Pierce SA, Guerchicoff A, Pollevick GD, Chan TY, Kabir MG, Cheng SH, Husain M, Antzelevitch C, Srivastava D, Gross GJ, Hui CC, Backx PH, Bruneau BG, The homeodomain transcription factor Irx5 establishes the mouse cardiac ventricular repolarization gradient. Cell. 2005 Oct 21;123(2):347-58 |
1 | J:265538 Fu A, Oberholtzer SM, Bagheri-Fam S, Rastetter RH, Holdreith C, Caceres VL, John SV, Shaw SA, Krentz KJ, Zhang X, Hui CC, Wilhelm D, Jorgensen JS, Dynamic expression patterns of Irx3 and Irx5 during germline nest breakdown and primordial follicle formation promote follicle survival in mouse ovaries. PLoS Genet. 2018 Aug;14(8):e1007488 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Irx6 Iroquois homeobox 6 | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1* | J:189955 Star EN, Zhu M, Shi Z, Liu H, Pashmforoush M, Sauve Y, Bruneau BG, Chow RL, Regulation of retinal interneuron subtype identity by the Iroquois homeobox gene Irx6. Development. 2012 Dec;139(24):4644-55 |
Isg15 ISG15 ubiquitin-like modifier (Synonyms: G1p2) | |
Results | Reference |
1 | J:288683 Gacem N, Kavo A, Zerad L, Richard L, Mathis S, Kapur RP, Parisot M, Amiel J, Dufour S, de la Grange P, Pingault V, Vallat JM, Bondurand N, ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. Nat Commun. 2020 Jan 10;11(1):198 |
1 | J:361606 Wei W, Gao X, Qian J, Li L, Zhao C, Xu L, Zhu Y, Liu Z, Liu N, Wang X, Jin Z, Liu B, Xu L, Dong J, Zhang S, Wang J, Zhang Y, Yu Y, Yan Z, Yang Y, Lu J, Fang Y, Yuan N, Wang J, Beclin 1 prevents ISG15-mediated cytokine storms to secure fetal hematopoiesis and survival. J Clin Invest. 2025 Feb 3;135(3) |
Isl1 ISL1 transcription factor, LIM/homeodomain (Synonyms: Islet 1) | |
Results | Reference |
2* | J:130196 Alfonsi F, Filippi P, Salaun D, deLapeyriere O, Durbec P, LIFR beta plays a major role in neuronal identity determination and glial differentiation in the mouse facial nucleus. Dev Biol. 2008 Jan 1;313(1):267-78 |
1 | J:91364 Arenkiel BR, Tvrdik P, Gaufo GO, Capecchi MR, Hoxb1 functions in both motoneurons and in tissues of the periphery to establish and maintain the proper neuronal circuitry. Genes Dev. 2004 Jul 1;18(13):1539-52 |
1 | J:320518 Belle M, Parray A, Belle M, Chedotal A, Nguyen-Ba-Charvet KT, PlexinA2 and Sema6A are required for retinal progenitor cell migration. Dev Growth Differ. 2016 Jun;58(5):492-502 |
1 | J:309359 Brinkmeier ML, Bando H, Camarano AC, Fujio S, Yoshimoto K, de Souza FS, Camper SA, Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. J Clin Invest. 2020 Aug 3;130(8):4501-4515 |
1 | J:178178 Bupesh M, Abellan A, Medina L, Genetic and experimental evidence supports the continuum of the central extended amygdala and a mutiple embryonic origin of its principal neurons. J Comp Neurol. 2011 Dec 1;519(17):3507-31 |
1 | J:233385 Castinetti F, Brinkmeier ML, Mortensen AH, Vella KR, Gergics P, Brue T, Hollenberg AN, Gan L, Camper SA, ISL1 Is Necessary for Maximal Thyrotrope Response to Hypothyroidism. Mol Endocrinol. 2015 Oct;29(10):1510-21 |
1* | J:243896 Chevalier M, Cardoit L, Moreau M, Sans N, Montcouquiol M, Simmers J, Thoby-Brisson M, The embryonic development of hindbrain respiratory networks is unaffected by mutation of the planar polarity protein Scribble. Neuroscience. 2017 Aug 15;357:160-171 |
2 | J:256285 Ching ST, Infante CR, Du W, Sharir A, Park S, Menke DB, Klein OD, Isl1 mediates mesenchymal expansion in the developing external genitalia via regulation of Bmp4, Fgf10 and Wnt5a. Hum Mol Genet. 2018 Jan 1;27(1):107-119 |
1 | J:267108 Cho E, Mysliwiec MR, Carlson CD, Ansari A, Schwartz RJ, Lee Y, Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development. J Biol Chem. 2018 Jul 27;293(30):11659-11673 |
1 | J:213234 Cho HH, Cargnin F, Kim Y, Lee B, Kwon RJ, Nam H, Shen R, Barnes AP, Lee JW, Lee S, Lee SK, Isl1 directly controls a cholinergic neuronal identity in the developing forebrain and spinal cord by forming cell type-specific complexes. PLoS Genet. 2014 Apr;10(4):e1004280 |
1* | J:170654 Das P, May CL, Expression analysis of the Islet-1 gene in the developing and adult gastrointestinal tract. Gene Expr Patterns. 2011 Mar-Apr;11(3-4):244-54 |
1* | J:121318 Davis SW, Camper SA, Noggin regulates Bmp4 activity during pituitary induction. Dev Biol. 2007 May 1;305(1):145-60 |
1 | J:172162 de Melo J, Zhou QP, Zhang Q, Zhang S, Fonseca M, Wigle JT, Eisenstat DD, Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development. Nucleic Acids Res. 2008 Feb;36(3):872-84 |
1 | J:353354 Desiderio S, Schwaller F, Tartour K, Padmanabhan K, Lewin GR, Carroll P, Marmigere F, Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2. Elife. 2024 Feb 22;12 |
1 | J:283226 Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld KA, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ, Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA. Cell Rep. 2019 Mar 26;26(13):3522-3536.e5 |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
1* | J:130185 Ellsworth BS, Butts DL, Camper SA, Mechanisms underlying pituitary hypoplasia and failed cell specification in Lhx3-deficient mice. Dev Biol. 2008 Jan 1;313(1):118-29 |
2 | J:237201 Espinosa-Medina I, Saha O, Boismoreau F, Chettouh Z, Rossi F, Richardson WD, Brunet JF, The sacral autonomic outflow is sympathetic. Science. 2016 Nov 18;354(6314):893-897 |
1 | J:172287 Esteve P, Sandonis A, Cardozo M, Malapeira J, Ibanez C, Crespo I, Marcos S, Gonzalez-Garcia S, Toribio ML, Arribas J, Shimono A, Guerrero I, Bovolenta P, SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis. Nat Neurosci. 2011 May;14(5):562-9 |
1 | J:176438 Esteve P, Sandonis A, Ibanez C, Shimono A, Guerrero I, Bovolenta P, Secreted frizzled-related proteins are required for Wnt/{beta}-catenin signalling activation in the vertebrate optic cup. Development. 2011 Oct;138(19):4179-84 |
1 | J:250440 Ferguson R, Serafeimidou-Pouliou E, Subramanian V, Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation. J Anat. 2016 Dec;229(6):871-891 |
1 | J:154447 Fragkouli A, van Wijk NV, Lopes R, Kessaris N, Pachnis V, LIM homeodomain transcription factor-dependent specification of bipotential MGE progenitors into cholinergic and GABAergic striatal interneurons. Development. 2009 Nov;136(22):3841-51 |
1 | J:180774 Grimsley-Myers CM, Sipe CW, Wu DK, Lu X, Redundant functions of Rac GTPases in inner ear morphogenesis. Dev Biol. 2012 Feb 15;362(2):172-86 |
1 | J:237540 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R, The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development. 2016 Nov 15;143(22):4182-4192 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:96397 Halfter W, Willem M, Mayer U, Basement membrane-dependent survival of retinal ganglion cells. Invest Ophthalmol Vis Sci. 2005 Mar;46(3):1000-9 |
1* | J:148194 Han DY, Kobayashi M, Nakano M, Atobe Y, Kadota T, Funakoshi K, Differential Islet-1 expression among lumbosacral spinal motor neurons in prenatal mouse. Brain Res. 2009 Apr 10;1265:30-6 |
1 | J:315755 Hancock ML, Nowakowski DW, Role LW, Talmage DA, Flanagan JG, Type III neuregulin 1 regulates pathfinding of sensory axons in the developing spinal cord and periphery. Development. 2011 Nov;138(22):4887-98 |
1* | J:62985 Helmbacher F, Schneider-Maunoury S, Topilko P, Tiret L, Charnay P, Targeting of the EphA4 tyrosine kinase receptor affects dorsal/ventral pathfinding of limb motor axons. Development. 2000 Aug;127(15):3313-24 |
1* | J:85445 Herrera E, Brown L, Aruga J, Rachel RA, Dolen G, Mikoshiba K, Brown S, Mason CA, Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell. 2003 Sep 5;114(5):545-57 |
1 | J:94392 Herrera E, Marcus R, Li S, Williams SE, Erskine L, Lai E, Mason C, Foxd1 is required for proper formation of the optic chiasm. Development. 2004 Nov;131(22):5727-39 |
1 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1 | J:188329 Huang WH, Tupal S, Huang TW, Ward CS, Neul JL, Klisch TJ, Gray PA, Zoghbi HY, Atoh1 Governs the Migration of Postmitotic Neurons that Shape Respiratory Effectiveness at Birth and Chemoresponsiveness in Adulthood. Neuron. 2012 Sep 6;75(5):799-809 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
1 | J:215576 Itoh T, Horiuchi M, Ikeda RH Jr, Xu J, Bannerman P, Pleasure D, Penninger JM, Tournier C, Itoh A, ZPK/DLK and MKK4 form the critical gateway to axotomy-induced motoneuron death in neonates. J Neurosci. 2014 Aug 6;34(32):10729-42 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1* | J:54064 Kablar B, Rudnicki MA, Development in the absence of skeletal muscle results in the sequential ablation of motor neurons from the spinal cord to the brain. Dev Biol. 1999 Apr 1;208(1):93-109 |
1 | J:201551 Ko HA, Chen SY, Chen HY, Hao HJ, Liu FC, Cell type-selective expression of the zinc finger-containing gene Nolz-1/Zfp503 in the developing mouse striatum. Neurosci Lett. 2013 Aug 26;548:44-9 |
1 | J:100207 Kobayashi K, Takahashi M, Matsushita N, Miyazaki J, Koike M, Yaginuma H, Osumi N, Kaibuchi K, Kobayashi K, Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase. J Neurosci. 2004 Apr 7;24(14):3480-8 |
1 | J:228865 Law C, Schaan Profes M, Levesque M, Kaltschmidt JA, Verhage M, Kania A, Normal Molecular Specification and Neurodegenerative Disease-Like Death of Spinal Neurons Lacking the SNARE-Associated Synaptic Protein Munc18-1. J Neurosci. 2016 Jan 13;36(2):561-76 |
1 | J:237344 Lee B, Lee S, Lee SK, Lee JW, The LIM-homeobox transcription factor Isl1 plays crucial roles in the development of multiple arcuate nucleus neurons. Development. 2016 Oct 15;143(20):3763-3773 |
2 | J:361228 Li Z, Shang Z, Sun M, Jiang X, Tian Y, Yang L, Wang Z, Su Z, Liu G, Li X, You Y, Yang Z, Xu Z, Zhang Z, Transcription factor Sp9 is a negative regulator of D1-type MSN development. Cell Death Discov. 2022 Jun 30;8(1):301 |
1* | J:91057 Louvi A, Sisodia SS, Grove EA, Presenilin 1 in migration and morphogenesis in the central nervous system. Development. 2004 Jul;131(13):3093-105 |
1 | J:241892 Marcucci F, Murcia-Belmonte V, Wang Q, Coca Y, Ferreiro-Galve S, Kuwajima T, Khalid S, Ross ME, Mason C, Herrera E, The Ciliary Margin Zone of the Mammalian Retina Generates Retinal Ganglion Cells. Cell Rep. 2016 Dec 20;17(12):3153-3164 |
1* | J:269981 Marcucci F, Soares CA, Mason C, Distinct timing of neurogenesis of ipsilateral and contralateral retinal ganglion cells. J Comp Neurol. 2019 Jan 1;527(1):212-224 |
1 | J:37118 McEvilly RJ, Erkman L, Luo L, Sawchenko PE, Ryan AF, Rosenfeld MG, Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature. 1996 Dec 12;384(6609):574-7 |
1 | J:201154 Meziane H, Fraulob V, Riet F, Krezel W, Selloum M, Geffarth M, Acampora D, Herault Y, Simeone A, Brand M, Dolle P, Rhinn M, The homeodomain factor Gbx1 is required for locomotion and cell specification in the dorsal spinal cord. PeerJ. 2013;1:e142 |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
1* | J:68840 Nakagawa Y, O'Leary DD, Combinatorial expression patterns of LIM-homeodomain and other regulatory genes parcellate developing thalamus. J Neurosci. 2001 Apr 15;21(8):2711-25 |
1 | J:134495 Nakamura S, Senzaki K, Yoshikawa M, Nishimura M, Inoue K, Ito Y, Ozaki S, Shiga T, Dynamic regulation of the expression of neurotrophin receptors by Runx3. Development. 2008 May;135(9):1703-11 |
1* | J:263835 Newman EA, Kim DW, Wan J, Wang J, Qian J, Blackshaw S, Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes. Dev Biol. 2018 Jul 15;439(2):102-111 |
1 | J:355222 Nord C, Jones I, Garcia-Maestre M, Hagglund AC, Carlsson L, Reduced mTORC1-signaling in progenitor cells leads to retinal lamination deficits. Dev Dyn. 2024 Oct;253(10):922-939 |
1 | J:290493 Peng YR, James RE, Yan W, Kay JN, Kolodkin AL, Sanes JR, Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch. Neuron. 2020 Feb 5;105(3):464-474.e6 |
1* | J:227089 Pirson M, Knoops B, Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617 |
1 | J:94587 Radde-Gallwitz K, Pan L, Gan L, Lin X, Segil N, Chen P, Expression of Islet1 marks the sensory and neuronal lineages in the mammalian inner ear. J Comp Neurol. 2004 Sep 27;477(4):412-21 |
1 | J:231738 Reed-Geaghan EG, Wright MC, See LA, Adelman PC, Lee KH, Koerber HR, Maricich SM, Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. J Neurosci. 2016 Apr 13;36(15):4362-76 |
1 | J:331367 Roussel J, Larcher R, Sicard P, Bideaux P, Richard S, Marmigere F, Thireau J, The autism-associated Meis2 gene is necessary for cardiac baroreflex regulation in mice. Sci Rep. 2022 Nov 23;12(1):20150 |
1 | J:123685 Saarimaki-Vire J, Peltopuro P, Lahti L, Naserke T, Blak AA, Vogt Weisenhorn DM, Yu K, Ornitz DM, Wurst W, Partanen J, Fibroblast growth factor receptors cooperate to regulate neural progenitor properties in the developing midbrain and hindbrain. J Neurosci. 2007 Aug 8;27(32):8581-92 |
1 | J:246732 Saller MM, Huettl RE, Hanuschick P, Amend AL, Alberton P, Aszodi A, Huber AB, The role of Sema3-Npn-1 signaling during diaphragm innervation and muscle development. J Cell Sci. 2016 Sep 01;129(17):3295-308 |
1 | J:287023 Schnerwitzki D, Perry S, Ivanova A, Caixeta FV, Cramer P, Gunther S, Weber K, Tafreshiha A, Becker L, Vargas Panesso IL, Klopstock T, Hrabe de Angelis M, Schmidt M, Kullander K, Englert C, Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord. Life Sci Alliance. 2018 Aug;1(4):e201800106 |
1 | J:328873 Shang Z, Yang L, Wang Z, Tian Y, Gao Y, Su Z, Guo R, Li W, Liu G, Li X, Yang Z, Li Z, Zhang Z, The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity. Front Cell Dev Biol. 2022;10:948331 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:357469 Sivori M, Dempsey B, Chettouh Z, Boismoreau F, Ayerdi M, et al., The pelvic organs receive no parasympathetic innervation. Elife. 2024;15 |
1 | J:350099 Song X, Chen H, Shang Z, Du H, Li Z, Wen Y, Liu G, Qi D, You Y, Yang Z, Zhang Z, Xu Z, Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons. Neurosci Bull. 2021 Jul;37(7):985-998 |
1 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1 | J:124714 Subramanian V, Feng Y, A new role for angiogenin in neurite growth and pathfinding: implications for amyotrophic lateral sclerosis. Hum Mol Genet. 2007 Jun 15;16(12):1445-53 |
1 | J:101739 Takeuchi JK, Mileikovskaia M, Koshiba-Takeuchi K, Heidt AB, Mori AD, Arruda EP, Gertsenstein M, Georges R, Davidson L, Mo R, Hui CC, Henkelman RM, Nemer M, Black BL, Nagy A, Bruneau BG, Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development. Development. 2005 May;132(10):2463-74 |
1 | J:342641 Tenney AP, Di Gioia SA, Webb BD, Chan WM, de Boer E, Garnai SJ, Barry BJ, Ray T, Kosicki M, Robson CD, Zhang Z, Collins TE, Gelber A, Pratt BM, Fujiwara Y, Varshney A, Lek M, Warburton PE, Van Ryzin C, Lehky TJ, Zalewski C, King KA, Brewer CC, Thurm A, Snow J, Facio FM, Narisu N, Bonnycastle LL, Swift A, Chines PS, Bell JL, Mohan S, Whitman MC, Staffieri SE, Elder JE, Demer JL, Torres A, Rachid E, Al-Haddad C, Boustany RM, Mackey DA, Brady AF, Fenollar-Cortes M, Fradin M, Kleefstra T, Padberg GW, Raskin S, Sato MT, Orkin SH, Parker SCJ, Hadlock TA, Vissers LELM, van Bokhoven H, Jabs EW, Collins FS, Pennacchio LA, Manoli I, Engle EC, Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis. Nat Genet. 2023 Jul;55(7):1149-1163 |
2 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1 | J:277837 Thoby-Brisson M, Bouvier J, Glasco DM, Stewart ME, Dean C, Murdoch JN, Champagnat J, Fortin G, Chandrasekhar A, Brainstem respiratory oscillators develop independently of neuronal migration defects in the Wnt/PCP mouse mutant looptail. PLoS One. 2012;7(2):e31140 |
1 | J:154456 Thompson H, Andrews W, Parnavelas JG, Erskine L, Robo2 is required for Slit-mediated intraretinal axon guidance. Dev Biol. 2009 Nov 15;335(2):418-26 |
1 | J:111137 Thompson H, Camand O, Barker D, Erskine L, Slit proteins regulate distinct aspects of retinal ganglion cell axon guidance within dorsal and ventral retina. J Neurosci. 2006 Aug 2;26(31):8082-91 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1* | J:223033 Tomas-Roca L, Tsaalbi-Shtylik A, Jansen JG, Singh MK, Epstein JA, Altunoglu U, Verzijl H, Soria L, van Beusekom E, Roscioli T, Iqbal Z, Gilissen C, Hoischen A, de Brouwer AP, Erasmus C, Schubert D, Brunner H, Perez Aytes A, Marin F, Aroca P, Kayserili H,Carta A, de Wind N, Padberg GW, van Bokhoven H, De novo mutations in PLXND1 and REV3L cause Mobius syndrome. Nat Commun. 2015;6:7199 |
1* | J:336871 Toonen JA, Ronchetti A, Sidjanin DJ, A Disintegrin and Metalloproteinase10 (ADAM10) Regulates NOTCH Signaling during Early Retinal Development. PLoS One. 2016;11(5):e0156184 |
1* | J:64588 Toresson H, Potter SS, Campbell K, Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for pax6 and gsh2. Development. 2000 Oct;127(20):4361-71 |
1 | J:116180 Wallen-Mackenzie A, Gezelius H, Thoby-Brisson M, Nygard A, Enjin A, Fujiyama F, Fortin G, Kullander K, Vesicular glutamate transporter 2 is required for central respiratory rhythm generation but not for locomotor central pattern generation. J Neurosci. 2006 Nov 22;26(47):12294-307 |
1 | J:136994 Wang J, Chan CK, Taylor JS, Chan SO, Localization of Nogo and its receptor in the optic pathway of mouse embryos. J Neurosci Res. 2008 Jun;86(8):1721-33 |
1* | J:180986 Wei Q, Condie BG, A focused in situ hybridization screen identifies candidate transcriptional regulators of thymic epithelial cell development and function. PLoS One. 2011;6(11):e26795 |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
1 | J:318286 Whitney IE, Kautzman AG, Reese BE, Alternative splicing of the LIM-homeodomain transcription factor Isl1 in the mouse retina. Mol Cell Neurosci. 2015 Mar;65:102-13 |
1* | J:307862 Wilkerson BA, Zebroski HL, Finkbeiner CR, Chitsazan AD, Beach KE, Sen N, Zhang RC, Bermingham-McDonogh O, Novel cell types and developmental lineages revealed by single-cell RNA-seq analysis of the mouse crista ampullaris. Elife. 2021 May 18;10:e60108 |
1 | J:362739 Wu Y, Qin K, Xu Y, Rajhans S, Vo T, Lopez KM, Liu J, Nipper MH, Deng J, Yin X, Ramjit LR, Ye Z, Luan Y, Arda HE, Wang P, Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation. Elife. 2024 Jul 25;13 |
1 | J:343328 Xie Z, Ma XH, Bai QF, Tang J, Sun JH, Jiang F, Guo W, Wang CM, Yang R, Wen YC, Wang FY, Chen YX, Zhang H, He DZ, Kelley MW, Yang S, Zhang WJ, ZBTB20 is essential for cochlear maturation and hearing in mice. Proc Natl Acad Sci U S A. 2023 Jun 13;120(24):e2220867120 |
1 | J:264125 Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z, SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. Development. 2018 Jul 23;145(14):dev165456 |
1 | J:242450 Yang Q, Liu S, Yin M, Yin Y, Zhou G, Zhou J, Ebf2 is required for development of dopamine neurons in the midbrain periaqueductal gray matter of mouse. Dev Neurobiol. 2015 Nov;75(11):1282-94 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
1* | J:299732 Zhou X, Zhong S, Peng H, Liu J, Ding W, Sun L, Ma Q, Liu Z, Chen R, Wu Q, Wang X, Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus. Nat Commun. 2020 Aug 13;11(1):4063 |
Isl2 insulin related protein 2 (islet 2) (Synonyms: 3110001N10Rik, islet 2, islet-2) | |
Results | Reference |
1* | J:243896 Chevalier M, Cardoit L, Moreau M, Sans N, Montcouquiol M, Simmers J, Thoby-Brisson M, The embryonic development of hindbrain respiratory networks is unaffected by mutation of the planar polarity protein Scribble. Neuroscience. 2017 Aug 15;357:160-171 |
2 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1 | J:160656 Eng SR, Dykes IM, Lanier J, Fedtsova N, Turner EE, POU-domain factor Brn3a regulates both distinct and common programs of gene expression in the spinal and trigeminal sensory ganglia. Neural Dev. 2007;2:3 |
1 | J:237201 Espinosa-Medina I, Saha O, Boismoreau F, Chettouh Z, Rossi F, Richardson WD, Brunet JF, The sacral autonomic outflow is sympathetic. Science. 2016 Nov 18;354(6314):893-897 |
1 | J:250440 Ferguson R, Serafeimidou-Pouliou E, Subramanian V, Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation. J Anat. 2016 Dec;229(6):871-891 |
1* | J:148194 Han DY, Kobayashi M, Nakano M, Atobe Y, Kadota T, Funakoshi K, Differential Islet-1 expression among lumbosacral spinal motor neurons in prenatal mouse. Brain Res. 2009 Apr 10;1265:30-6 |
1 | J:315755 Hancock ML, Nowakowski DW, Role LW, Talmage DA, Flanagan JG, Type III neuregulin 1 regulates pathfinding of sensory axons in the developing spinal cord and periphery. Development. 2011 Nov;138(22):4887-98 |
1* | J:85445 Herrera E, Brown L, Aruga J, Rachel RA, Dolen G, Mikoshiba K, Brown S, Mason CA, Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell. 2003 Sep 5;114(5):545-57 |
2 | J:94392 Herrera E, Marcus R, Li S, Williams SE, Erskine L, Lai E, Mason C, Foxd1 is required for proper formation of the optic chiasm. Development. 2004 Nov;131(22):5727-39 |
1 | J:215576 Itoh T, Horiuchi M, Ikeda RH Jr, Xu J, Bannerman P, Pleasure D, Penninger JM, Tournier C, Itoh A, ZPK/DLK and MKK4 form the critical gateway to axotomy-induced motoneuron death in neonates. J Neurosci. 2014 Aug 6;34(32):10729-42 |
1* | J:54064 Kablar B, Rudnicki MA, Development in the absence of skeletal muscle results in the sequential ablation of motor neurons from the spinal cord to the brain. Dev Biol. 1999 Apr 1;208(1):93-109 |
1 | J:355222 Nord C, Jones I, Garcia-Maestre M, Hagglund AC, Carlsson L, Reduced mTORC1-signaling in progenitor cells leads to retinal lamination deficits. Dev Dyn. 2024 Oct;253(10):922-939 |
1* | J:227089 Pirson M, Knoops B, Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617 |
1 | J:123264 Quina LA, Pak W, Lanier J, Banwait P, Gratwick K, Liu Y, Velasquez T, O'Leary DD, Goulding M, Turner EE, Brn3a-expressing retinal ganglion cells project specifically to thalamocortical and collicular visual pathways. J Neurosci. 2005 Dec 14;25(50):11595-604 |
1 | J:231738 Reed-Geaghan EG, Wright MC, See LA, Adelman PC, Lee KH, Koerber HR, Maricich SM, Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. J Neurosci. 2016 Apr 13;36(15):4362-76 |
1 | J:246732 Saller MM, Huettl RE, Hanuschick P, Amend AL, Alberton P, Aszodi A, Huber AB, The role of Sema3-Npn-1 signaling during diaphragm innervation and muscle development. J Cell Sci. 2016 Sep 01;129(17):3295-308 |
1 | J:287023 Schnerwitzki D, Perry S, Ivanova A, Caixeta FV, Cramer P, Gunther S, Weber K, Tafreshiha A, Becker L, Vargas Panesso IL, Klopstock T, Hrabe de Angelis M, Schmidt M, Kullander K, Englert C, Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord. Life Sci Alliance. 2018 Aug;1(4):e201800106 |
1 | J:124714 Subramanian V, Feng Y, A new role for angiogenin in neurite growth and pathfinding: implications for amyotrophic lateral sclerosis. Hum Mol Genet. 2007 Jun 15;16(12):1445-53 |
1 | J:277837 Thoby-Brisson M, Bouvier J, Glasco DM, Stewart ME, Dean C, Murdoch JN, Champagnat J, Fortin G, Chandrasekhar A, Brainstem respiratory oscillators develop independently of neuronal migration defects in the Wnt/PCP mouse mutant looptail. PLoS One. 2012;7(2):e31140 |
1 | J:154456 Thompson H, Andrews W, Parnavelas JG, Erskine L, Robo2 is required for Slit-mediated intraretinal axon guidance. Dev Biol. 2009 Nov 15;335(2):418-26 |
1 | J:116180 Wallen-Mackenzie A, Gezelius H, Thoby-Brisson M, Nygard A, Enjin A, Fujiyama F, Fortin G, Kullander K, Vesicular glutamate transporter 2 is required for central respiratory rhythm generation but not for locomotor central pattern generation. J Neurosci. 2006 Nov 22;26(47):12294-307 |
Islr immunoglobulin superfamily containing leucine-rich repeat | |
Results | Reference |
1 | J:297219 Xu J, Tang Y, Sheng X, Tian Y, Deng M, Du S, Lv C, Li G, Pan Y, Song Y, Lou P, Luo Y, Li Y, Zhang B, Chen Y, Liu Z, Cong Y, Plikus MV, Meng Q, Zhou Z, Yu Z, Secreted stromal protein ISLR promotes intestinal regeneration by suppressing epithelial Hippo signaling. EMBO J. 2020 Apr 1;39(7):e103255 |
Islr2 immunoglobulin superfamily containing leucine-rich repeat 2 (Synonyms: B930052A04Rik, Linx, mbu-3, mKIAA1465) | |
Results | Reference |
1 | J:338454 Marfull-Oromi P, Fleitas C, Zammou B, Rocandio D, Ballester-Lurbe B, Terrado J, Perez-Roger I, Espinet C, Egea J, Genetic ablation of the Rho GTPase Rnd3 triggers developmental defects in internal capsule and the globus pallidus formation. J Neurochem. 2021 Jul;158(2):197-216 |
1 | J:326535 Petitpre C, Faure L, Uhl P, Fontanet P, Filova I, Pavlinkova G, Adameyko I, Hadjab S, Lallemend F, Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification. Nat Commun. 2022 Jul 5;13(1):3878 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Ist1 increased sodium tolerance 1 homolog (yeast) (Synonyms: 2400003C14Rik, mKIAA0174) | |
Results | Reference |
1* | J:339600 Hermosilla Aguayo V, Martin P, Tian N, Zheng J, Aho R, Losa M, Selleri L, ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42 |
Itga2 integrin alpha 2 (Synonyms: CD49B, DX5, VLA-2 receptor, alpha 2 subunit) | |
Results | Reference |
1 | J:92200 Popova SN, Rodriguez-Sanchez B, Liden A, Betsholtz C, Van Den Bos T, Gullberg D, The mesenchymal alpha11beta1 integrin attenuates PDGF-BB-stimulated chemotaxis of embryonic fibroblasts on collagens. Dev Biol. 2004 Jun 15;270(2):427-42 |
2* | J:17839 Wu JE, Santoro SA, Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development. Dev Dyn. 1994 Apr;199(4):292-314 |
1* | J:33225 Wu JE, Santoro SA, Differential expression of integrin alpha subunits supports distinct roles during lung branching morphogenesis. Dev Dyn. 1996 Jun;206(2):169-81 |
Itga3 integrin alpha 3 (Synonyms: alpha3-integrin, VLA-3 alpha 3) | |
Results | Reference |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1* | J:32724 Hierck BP, Poelmann RE, van Iperen L, Brouwer A, Gittenberger-de Groot AC, Differential expression of alpha-6 and other subunits of laminin binding integrins during development of the murine heart. Dev Dyn. 1996 May;206(1):100-11 |
1 | J:316440 Imanishi H, Tsuruta D, Tateishi C, Sugawara K, Kobayashi H, Ishii M, Kishi K, Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis. Med Mol Morphol. 2014 Mar;47(1):38-42 |
1* | J:332639 Rinta-Jaskari MM, Naillat F, Ruotsalainen HJ, Koivunen JT, Sasaki T, Pietila I, Elamaa HP, Kaur I, Manninen A, Vainio SJ, Pihlajaniemi TA, Temporally and Spatially Regulated Collagen XVIII Isoforms Are Involved in Ureteric Tree Development Via the TSP1-like Domain. Matrix Biol. 2023 Jan 6; |
1 | J:251846 Ross JA, Webster RG, Lechertier T, Reynolds LE, Turmaine M, Bencze M, Jamshidi Y, Cetin H, Muntoni F, Beeson D, Hodilvala-Dilke K, Conti FJ, Multiple roles of integrin-alpha3 at the neuromuscular junction. J Cell Sci. 2017 May 15;130(10):1772-1784 |
1 | J:77999 Sugitani Y, Nakai S, Minowa O, Nishi M, Jishage K, Kawano H, Mori K, Ogawa M, Noda T, Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. Genes Dev. 2002 Jul 15;16(14):1760-5 |
1* | J:33225 Wu JE, Santoro SA, Differential expression of integrin alpha subunits supports distinct roles during lung branching morphogenesis. Dev Dyn. 1996 Jun;206(2):169-81 |
Itga5 integrin alpha 5 (fibronectin receptor alpha) (Synonyms: Cd49e, Fnra) | |
Results | Reference |
1 | J:331894 Alcantara MC, Suzuki K, Acebedo AR, Kajioka D, Hirohata S, Kaisho T, Hatano Y, Yamagata K, Takahashi S, Yamada G, Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice. iScience. 2022 Dec 22;25(12):105609 |
1* | J:163086 do Carmo Costa M, Bajanca F, Rodrigues AJ, Tome RJ, Corthals G, Macedo-Ribeiro S, Paulson HL, Logarinho E, Maciel P, Ataxin-3 plays a role in mouse myogenic differentiation through regulation of integrin subunit levels. PLoS One. 2010;5(7):e11728 |
1 | J:228882 Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS, Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016 Jan 1;409(1):218-33 |
1* | J:239792 Hong KY, Bae H, Park I, Park DY, Kim KH, Kubota Y, Cho ES, Kim H, Adams RH, Yoo OJ, Koh GY, Perilipin+ embryonic preadipocytes actively proliferate along growing vasculatures for adipose expansion. Development. 2015 Aug 01;142(15):2623-32 |
2* | J:33979 Yamada S, Brown KE, Yamada KM, Differential mRNA regulation of integrin subunits alpha V, beta 1, beta 3, and beta 5 during mouse embryonic organogenesis. Cell Adhes Commun. 1995 Nov;3(4):311-25 |
Itga6 integrin alpha 6 (Synonyms: 5033401O05Rik, Cd49f) | |
Results | Reference |
1 | J:327292 Bakhti M, Bastidas-Ponce A, Tritschler S, Czarnecki O, Tarquis-Medina M, Nedvedova E, Jaki J, Willmann SJ, Scheibner K, Cota P, Salinno C, Boldt K, Horn N, Ueffing M, Burtscher I, Theis FJ, Coskun U, Lickert H, Synaptotagmin-13 orchestrates pancreatic endocrine cell egression and islet morphogenesis. Nat Commun. 2022 Aug 4;13(1):4540 |
1 | J:276488 Bilodeau M, Shojaie S, Ackerley C, Post M, Rossant J, Identification of a proximal progenitor population from murine fetal lungs with clonogenic and multilineage differentiation potential. Stem Cell Reports. 2014 Oct 14;3(4):634-49 |
1 | J:179898 Coate TM, Raft S, Zhao X, Ryan AK, Crenshaw EB 3rd, Kelley MW, Otic Mesenchyme Cells Regulate Spiral Ganglion Axon Fasciculation through a Pou3f4/EphA4 Signaling Pathway. Neuron. 2012 Jan 12;73(1):49-63 |
1 | J:306061 Damen M, Wirtz L, Soroka E, Khatif H, Kukat C, Simons BD, Bazzi H, High proliferation and delamination during skin epidermal stratification. Nat Commun. 2021 May 28;12(1):3227 |
1 | J:346123 Darrigrand JF, Salowka A, Torres-Cano A, Tapia-Rojo R, Zhu T, Garcia-Manyes S, Spagnoli FM, Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner. Dev Cell. 2024 Feb 5;59(3):326-338.e5 |
1 | J:291945 De Arcangelis A, Hamade H, Alpy F, Normand S, Bruyere E, Lefebvre O, Mechine-Neuville A, Siebert S, Pfister V, Lepage P, Laquerriere P, Dembele D, Delanoye-Crespin A, Rodius S, Robine S, Kedinger M, Van Seuningen I, Simon-Assmann P, Chamaillard M, Labouesse M, Georges-Labouesse E, Hemidesmosome integrity protects the colon against colitis and colorectal cancer. Gut. 2017 Oct;66(10):1748-1760 |
1 | J:119006 de Guzman Strong C, Wertz PW, Wang C, Yang F, Meltzer PS, Andl T, Millar SE, Ho IC, Pai SY, Segre JA, Lipid defect underlies selective skin barrier impairment of an epidermal-specific deletion of Gata-3. J Cell Biol. 2006 Nov 20;175(4):661-70 |
1 | J:119851 DiPersio CM, van der Neut R, Georges-Labouesse E, Kreidberg JA, Sonnenberg A, Hynes RO, alpha3beta1 and alpha6beta4 integrin receptors for laminin-5 are not essential for epidermal morphogenesis and homeostasis during skin development. J Cell Sci. 2000 Sep;113(Pt 17):3051-62 |
2* | J:37568 Falk M, Salmivirta K, Durbeej M, Larsson E, Ekblom M, Vestweber D, Ekblom P, Integrin alpha 6B beta 1 is involved in kidney tubulogenesis in vitro. J Cell Sci. 1996 Dec;109(Pt 12):2801-10 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
1 | J:38205 Kashimata M, Gresik EW, Epidermal growth factor system is a physiological regulator of development of the mouse fetal submandibular gland and regulates expression of the alpha6-integrin subunit. Dev Dyn. 1997 Feb;208(2):149-61 |
1 | J:171374 Osorio KM, Lilja KC, Tumbar T, Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol. 2011 Apr 4;193(1):235-50 |
2* | J:31158 Salmivirta K, Gullberg D, Hirsch E, Altruda F, Ekblom P, Integrin subunit expression associated with epithelial-mesenchymal interactions during murine tooth development. Dev Dyn. 1996 Feb;205(2):104-13 |
1* | J:33225 Wu JE, Santoro SA, Differential expression of integrin alpha subunits supports distinct roles during lung branching morphogenesis. Dev Dyn. 1996 Jun;206(2):169-81 |
1 | J:49158 Zuccotti M, Rossi PG, Fiorillo E, Garagna S, Forabosco A, Redi CA, Timing of gene expression and oolemma localization of mouse alpha6 and beta1 integrin subunits during oogenesis. Dev Biol. 1998 Aug 1;200(1):27-34 |
Itga7 integrin alpha 7 (Synonyms: [a]7, alpha7) | |
Results | Reference |
1* | J:32724 Hierck BP, Poelmann RE, van Iperen L, Brouwer A, Gittenberger-de Groot AC, Differential expression of alpha-6 and other subunits of laminin binding integrins during development of the murine heart. Dev Dyn. 1996 May;206(1):100-11 |
Itga8 integrin alpha 8 | |
Results | Reference |
1* | J:286571 Denda S, Reichardt LF, Muller U, Identification of osteopontin as a novel ligand for the integrin alpha8 beta1 and potential roles for this integrin-ligand interaction in kidney morphogenesis. Mol Biol Cell. 1998 Jun;9(6):1425-35 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1 | J:152844 Driskell RR, Giangreco A, Jensen KB, Mulder KW, Watt FM, Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis. Development. 2009 Aug;136(16):2815-23 |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:170886 Fujiwara H, Ferreira M, Donati G, Marciano DK, Linton JM, Sato Y, Hartner A, Sekiguchi K, Reichardt LF, Watt FM, The basement membrane of hair follicle stem cells is a muscle cell niche. Cell. 2011 Feb 18;144(4):577-89 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1* | J:202344 Lesko MH, Driskell RR, Kretzschmar K, Goldie SJ, Watt FM, Sox2 modulates the function of two distinct cell lineages in mouse skin. Dev Biol. 2013 Oct 1;382(1):15-26 |
2* | J:38838 Muller U, Wang D, Denda S, Meneses JJ, Pedersen RA, Reichardt LF, Integrin alpha8beta1 is critically important for epithelial-mesenchymal interactions during kidney morphogenesis. Cell. 1997 Mar 7;88(5):603-13 |
1 | J:263065 Ogawa T, Li Y, Lua I, Hartner A, Asahina K, Isolation of a unique hepatic stellate cell population expressing integrin alpha8 from embryonic mouse livers. Dev Dyn. 2018 Jun;247(6):867-881 |
1 | J:87910 Scherberich A, Tucker RP, Samandari E, Brown-Luedi M, Martin D, Chiquet-Ehrismann R, Murine tenascin-W: a novel mammalian tenascin expressed in kidney and at sites of bone and smooth muscle development. J Cell Sci. 2004 Feb 1;117(Pt 4):571-81 |
1 | J:85775 Wagner TE, Frevert CW, Herzog EL, Schnapp LM, Expression of the integrin subunit alpha8 in murine lung development. J Histochem Cytochem. 2003 Oct;51(10):1307-15 |
Itga9 integrin alpha 9 (Synonyms: 2610002H11Rik, 6720458D17Rik, D9Ertd428e) | |
Results | Reference |
1 | J:152968 Bazigou E, Xie S, Chen C, Weston A, Miura N, Sorokin L, Adams R, Muro AF, Sheppard D, Makinen T, Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis. Dev Cell. 2009 Aug;17(2):175-86 |
1 | J:228882 Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS, Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016 Jan 1;409(1):218-33 |
1* | J:315946 Sato-Nishiuchi R, Nakano I, Ozawa A, Sato Y, Takeichi M, Kiyozumi D, Yamazaki K, Yasunaga T, Futaki S, Sekiguchi K, Polydom/SVEP1 is a ligand for integrin alpha9beta1. J Biol Chem. 2012 Jul 20;287(30):25615-30 |
1* | J:29945 Wang A, Patrone L, McDonald JA, Sheppard D, Expression of the integrin subunit alpha 9 in the murine embryo. Dev Dyn. 1995 Dec;204(4):421-31 |
Itga10 integrin, alpha 10 | |
Results | Reference |
1 | J:92200 Popova SN, Rodriguez-Sanchez B, Liden A, Betsholtz C, Van Den Bos T, Gullberg D, The mesenchymal alpha11beta1 integrin attenuates PDGF-BB-stimulated chemotaxis of embryonic fibroblasts on collagens. Dev Biol. 2004 Jun 15;270(2):427-42 |
Itga11 integrin alpha 11 (Synonyms: 4732459H24Rik) | |
Results | Reference |
1* | J:329340 Alam J, Musiime M, Romaine A, Sawant M, Melleby AO, Lu N, Eckes B, Christensen G, Gullberg D, Generation of a novel mouse strain with fibroblast-specific expression of Cre recombinase. Matrix Biol Plus. 2020;8:100045 |
2 | J:92200 Popova SN, Rodriguez-Sanchez B, Liden A, Betsholtz C, Van Den Bos T, Gullberg D, The mesenchymal alpha11beta1 integrin attenuates PDGF-BB-stimulated chemotaxis of embryonic fibroblasts on collagens. Dev Biol. 2004 Jun 15;270(2):427-42 |
Itgam integrin alpha M (Synonyms: Cd11b, CD11b/CD18, CD11B (p170), complement component receptor 3 alpha, complement receptor type 3, CR3, F730045J24Rik, Ly-40, Mac-1, Mac-1a, Mac-1 alpha) | |
Results | Reference |
1 | J:87395 Eberl G, Marmon S, Sunshine MJ, Rennert PD, Choi Y, Littman DR, An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat Immunol. 2004 Jan;5(1):64-73 |
1* | J:59927 Guerriero A, Langmuir PB, Spain LM, Scott EW, PU.1 is required for myeloid-derived but not lymphoid-derived dendritic cells. Blood. 2000 Feb 1;95(3):879-85 |
1 | J:47178 Hughes DA, Gordon S, Expression and function of the type 3 complement receptor in tissues of the developing mouse. J Immunol. 1998 May 1;160(9):4543-52 |
1 | J:309657 Kishimoto I, Okano T, Nishimura K, Motohashi T, Omori K, Early Development of Resident Macrophages in the Mouse Cochlea Depends on Yolk Sac Hematopoiesis. Front Neurol. 2019;10:1115 |
1 | J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
Itgav integrin alpha V (Synonyms: 1110004F14Rik, 2610028E01Rik, alphav-integrin, CD51, D430040G12Rik, vitronectin receptor alpha polypeptide (VNRA)) | |
Results | Reference |
2* | J:31158 Salmivirta K, Gullberg D, Hirsch E, Altruda F, Ekblom P, Integrin subunit expression associated with epithelial-mesenchymal interactions during murine tooth development. Dev Dyn. 1996 Feb;205(2):104-13 |
1 | J:222261 Tan KS, Inoue T, Kulkeaw K, Tanaka Y, Lai MI, Sugiyama D, Localized SCF and IGF-1 secretion enhances erythropoiesis in the spleen of murine embryos. Biol Open. 2015;4(5):596-607 |
Itgax integrin alpha X (Synonyms: Cd11c, CD11C (p150) alpha polypeptide, CR4) | |
Results | Reference |
1* | J:59927 Guerriero A, Langmuir PB, Spain LM, Scott EW, PU.1 is required for myeloid-derived but not lymphoid-derived dendritic cells. Blood. 2000 Feb 1;95(3):879-85 |
Itgb1 integrin beta 1 (fibronectin receptor beta) (Synonyms: 4633401G24Rik, beta1 integrin, CD29, Fnrb, Gm9863) | |
Results | Reference |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:79739 Georges-Labouesse E, Mark M, Messaddeq N, Gansmuller A, Essential role of alpha 6 integrins in cortical and retinal lamination. Curr Biol. 1998 Aug 27;8(17):983-6 |
1 | J:146619 Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong TT, Shaw RM, Srivastava D, Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell. 2009 Feb;16(2):233-44 |
1 | J:38205 Kashimata M, Gresik EW, Epidermal growth factor system is a physiological regulator of development of the mouse fetal submandibular gland and regulates expression of the alpha6-integrin subunit. Dev Dyn. 1997 Feb;208(2):149-61 |
1 | J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47 |
1 | J:321068 Maimets M, Pedersen MT, Guiu J, Dreier J, Thodberg M, Antoku Y, Schweiger PJ, Rib L, Bressan RB, Miao Y, Garcia KC, Sandelin A, Serup P, Jensen KB, Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling. Nat Commun. 2022 Feb 7;13(1):715 |
1 | J:236785 Pathania M, Wang Y, Simirskii VN, Duncan MK, beta1-integrin controls cell fate specification in early lens development. Differentiation. 2016 Oct - Nov;92(4):133-147 |
1* | J:332639 Rinta-Jaskari MM, Naillat F, Ruotsalainen HJ, Koivunen JT, Sasaki T, Pietila I, Elamaa HP, Kaur I, Manninen A, Vainio SJ, Pihlajaniemi TA, Temporally and Spatially Regulated Collagen XVIII Isoforms Are Involved in Ureteric Tree Development Via the TSP1-like Domain. Matrix Biol. 2023 Jan 6; |
1 | J:266746 Rudkouskaya A, Welch I, Dagnino L, ILK modulates epithelial polarity and matrix formation in hair follicles. Mol Biol Cell. 2014 Mar;25(5):620-32 |
1* | J:31158 Salmivirta K, Gullberg D, Hirsch E, Altruda F, Ekblom P, Integrin subunit expression associated with epithelial-mesenchymal interactions during murine tooth development. Dev Dyn. 1996 Feb;205(2):104-13 |
1 | J:238844 Scully KM, Skowronska-Krawczyk D, Krawczyk M, Merkurjev D, Taylor H, Livolsi A, Tollkuhn J, Stan RV, Rosenfeld MG, Epithelial cell integrin beta1 is required for developmental angiogenesis in the pituitary gland. Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):13408-13413 |
1 | J:44406 van der Flier A, Gaspar AC, Thorsteinsdottir S, Baudoin C, Groeneveld E, Mummery CL, Sonnenberg A, Spatial and temporal expression of the beta1D integrin during mouse development. Dev Dyn. 1997 Dec;210(4):472-86 |
1 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
1* | J:17839 Wu JE, Santoro SA, Complex patterns of expression suggest extensive roles for the alpha 2 beta 1 integrin in murine development. Dev Dyn. 1994 Apr;199(4):292-314 |
2* | J:33979 Yamada S, Brown KE, Yamada KM, Differential mRNA regulation of integrin subunits alpha V, beta 1, beta 3, and beta 5 during mouse embryonic organogenesis. Cell Adhes Commun. 1995 Nov;3(4):311-25 |
1 | J:358835 Zhang J, Gao J, Zeng X, Wang Z, Chen C, Rong C, Li S, Cai L, Wang L, Zhang L, Tian Z, A novel Cdc42-YAP-fibronectin signaling axis regulates ameloblast differentiation during early enamel formation. Biochim Biophys Acta Mol Basis Dis. 2024 Nov 14;1871(2):167570 |
1 | J:49158 Zuccotti M, Rossi PG, Fiorillo E, Garagna S, Forabosco A, Redi CA, Timing of gene expression and oolemma localization of mouse alpha6 and beta1 integrin subunits during oogenesis. Dev Biol. 1998 Aug 1;200(1):27-34 |
Itgb3 integrin beta 3 (Synonyms: CD61, platelet glycoprotein IIIa (GP3A)) | |
Results | Reference |
1 | J:232801 Misra A, Sheikh AQ, Kumar A, Luo J, Zhang J, Hinton RB, Smoot L, Kaplan P, Urban Z, Qyang Y, Tellides G, Greif DM, Integrin beta3 inhibition is a therapeutic strategy for supravalvular aortic stenosis. J Exp Med. 2016 Mar 7;213(3):451-63 |
1 | J:276880 Motch Perrine SM, Wu M, Stephens NB, Kriti D, van Bakel H, Jabs EW, Richtsmeier JT, Mandibular dysmorphology due to abnormal embryonic osteogenesis in FGFR2-related craniosynostosis mice. Dis Model Mech. 2019 May 30;12(5):dmm038513 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
2* | J:33979 Yamada S, Brown KE, Yamada KM, Differential mRNA regulation of integrin subunits alpha V, beta 1, beta 3, and beta 5 during mouse embryonic organogenesis. Cell Adhes Commun. 1995 Nov;3(4):311-25 |
Itgb4 integrin beta 4 (Synonyms: CD104) | |
Results | Reference |
1 | J:346910 Ayyangar U, Karkhanis A, Tay H, Afandi AFB, Bhattacharjee O, Ks L, Lee SH, Chan J, Raghavan S, Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin. EMBO J. 2024 Apr;43(7):1113-1134 |
1 | J:235730 Byrd KM, Lough KJ, Patel JH, Descovich CP, Curtis TA, Williams SE, LGN plays distinct roles in oral epithelial stratification, filiform papilla morphogenesis and hair follicle development. Development. 2016 Aug 1;143(15):2803-17 |
1 | J:272608 Cohen I, Zhao D, Menon G, Nakayama M, Koseki H, Zheng D, Ezhkova E, PRC1 preserves epidermal tissue integrity independently of PRC2. Genes Dev. 2019 Jan 1;33(1-2):55-60 |
1 | J:291945 De Arcangelis A, Hamade H, Alpy F, Normand S, Bruyere E, Lefebvre O, Mechine-Neuville A, Siebert S, Pfister V, Lepage P, Laquerriere P, Dembele D, Delanoye-Crespin A, Rodius S, Robine S, Kedinger M, Van Seuningen I, Simon-Assmann P, Chamaillard M, Labouesse M, Georges-Labouesse E, Hemidesmosome integrity protects the colon against colitis and colorectal cancer. Gut. 2017 Oct;66(10):1748-1760 |
1 | J:242729 Ding X, Bloch W, Iden S, Ruegg MA, Hall MN, Leptin M, Partridge L, Eming SA, mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation. Nat Commun. 2016 Oct 27;7:13226 |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1 | J:79739 Georges-Labouesse E, Mark M, Messaddeq N, Gansmuller A, Essential role of alpha 6 integrins in cortical and retinal lamination. Curr Biol. 1998 Aug 27;8(17):983-6 |
1 | J:196480 Grisanti L, Clavel C, Cai X, Rezza A, Tsai SY, Sennett R, Mumau M, Cai CL, Rendl M, Tbx18 targets dermal condensates for labeling, isolation, and gene ablation during embryonic hair follicle formation. J Invest Dermatol. 2013 Feb;133(2):344-53 |
1 | J:316440 Imanishi H, Tsuruta D, Tateishi C, Sugawara K, Kobayashi H, Ishii M, Kishi K, Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis. Med Mol Morphol. 2014 Mar;47(1):38-42 |
1 | J:38205 Kashimata M, Gresik EW, Epidermal growth factor system is a physiological regulator of development of the mouse fetal submandibular gland and regulates expression of the alpha6-integrin subunit. Dev Dyn. 1997 Feb;208(2):149-61 |
1* | J:203995 Lee S, Kong Y, Weatherbee SD, Forward genetics identifies Kdf1/1810019J16Rik as an essential regulator of the proliferation-differentiation decision in epidermal progenitor cells. Dev Biol. 2013 Nov 15;383(2):201-13 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
1 | J:279389 Miao Q, Hill MC, Chen F, Mo Q, Ku AT, Ramos C, Sock E, Lefebvre V, Nguyen H, SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair. Nat Commun. 2019 Sep 6;10(1):4042 |
1 | J:182928 Nagarajan P, Chin SS, Wang D, Liu S, Sinha S, Garrett-Sinha LA, Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators. J Cell Sci. 2010 Oct 15;123(Pt 20):3566-75 |
1 | J:171374 Osorio KM, Lilja KC, Tumbar T, Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol. 2011 Apr 4;193(1):235-50 |
1 | J:252201 Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A, p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct;137(10):2157-2167 |
2* | J:31158 Salmivirta K, Gullberg D, Hirsch E, Altruda F, Ekblom P, Integrin subunit expression associated with epithelial-mesenchymal interactions during murine tooth development. Dev Dyn. 1996 Feb;205(2):104-13 |
1 | J:186971 Shalom-Feuerstein R, Lena AM, Zhou H, De La Forest Divonne S, Van Bokhoven H, Candi E, Melino G, Aberdam D, DeltaNp63 is an ectodermal gatekeeper of epidermal morphogenesis. Cell Death Differ. 2011 May;18(5):887-96 |
1 | J:338452 Wang D, Li H, Chandel NS, Dou Y, Yi R, MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters. Nat Commun. 2023 Jul 21;14(1):4404 |
Itgb5 integrin beta 5 (Synonyms: [b]-5, [b]5, [b]5A, [b]5B, beta-5, beta5, ESTM23) | |
Results | Reference |
1* | J:79938 Le Gat L, Bonnel S, Gogat K, Brizard M, Van Den Berghe L, Kobetz A, Gadin S, Dureau P, Dufier J L, Abitbol M, Menasche M, Prominent beta-5 gene expression in the cardiovascular system and in the cartilaginous primordiae of the skeleton during mouse development. Cell Adhes Commun. 2001;8(3):99-112 |
2* | J:33979 Yamada S, Brown KE, Yamada KM, Differential mRNA regulation of integrin subunits alpha V, beta 1, beta 3, and beta 5 during mouse embryonic organogenesis. Cell Adhes Commun. 1995 Nov;3(4):311-25 |
Itgb6 integrin beta 6 (Synonyms: 2210409C20Rik, 4831415H04Rik) | |
Results | Reference |
2 | J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47 |
Itih4 inter alpha-trypsin inhibitor, heavy chain 4 (Synonyms: Itih-4) | |
Results | Reference |
1 | J:73656 Bhanumathy CD, Tang Y, Monga SP, Katuri V, Cox JA, Mishra B, Mishra L, Itih-4, a serine protease inhibitor regulated in interleukin-6-dependent liver formation: role in liver development and regeneration. Dev Dyn. 2002 Jan;223(1):59-69 |
Itih5 inter-alpha-trypsin inhibitor, heavy chain 5 (Synonyms: 4631408O11Rik, 5430408M01Rik) | |
Results | Reference |
2* | J:317540 Morcel K, Watrin T, Jaffre F, Deschamps S, Omilli F, Pellerin I, Leveque J, Guerrier D, Involvement of ITIH5, a candidate gene for congenital uterovaginal aplasia (Mayer-Rokitansky-Kuster-Hauser syndrome), in female genital tract development. Gene Expr. 2012;15(5-6):207-14 |
Itm2a integral membrane protein 2A (Synonyms: Bricd2a, Itm2) | |
Results | Reference |
1* | J:75158 Barber TD, Barber MC, Tomescu O, Barr FG, Ruben S, Friedman TB, Identification of Target Genes Regulated by PAX3 and PAX3--FKHR in Embryogenesis and Alveolar Rhabdomyosarcoma. Genomics. 2002 Mar;79(3):278-84 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Itpa inosine triphosphatase (nucleoside triphosphate pyrophosphatase) (Synonyms: 2010016I08Rik, Itp) | |
Results | Reference |
1* | J:273099 Handley MT, Reddy K, Wills J, Rosser E, Kamath A, Halachev M, Falkous G, Williams D, Cox P, Meynert A, Raymond ES, Morrison H, Brown S, Allan E, Aligianis I, Jackson AP, Ramsahoye BH, von Kriegsheim A, Taylor RW, Finch AJ, FitzPatrick DR, ITPase deficiency causes a Martsolf-like syndrome with a lethal infantile dilated cardiomyopathy. PLoS Genet. 2019 Mar;15(3):e1007605 |
Itpr1 inositol 1,4,5-trisphosphate receptor 1 (Synonyms: InsP3R type I, Ip3r, IP3R1, Itpr-1, opt, P400, Pcp-1, Pcp1, wblo) | |
Results | Reference |
2* | J:79406 Faure AV, Grunwald D, Moutin MJ, Hilly M, Mauger JP, Marty I, De Waard M, Villaz M, Albrieux M, Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex. Eur J Neurosci. 2001 Nov;14(10):1613-22 |
1* | J:231957 McEntagart M, Williamson KA, Rainger JK, Wheeler A, Seawright A, De Baere E, Verdin H, Bergendahl LT, Quigley A, Rainger J, Dixit A, Sarkar A, Lopez Laso E, Sanchez-Carpintero R, Barrio J, Bitoun P, Prescott T, Riise R, McKee S, Cook J, McKie L, Ceulemans B, Meire F, Temple IK, Prieur F, Williams J, Clouston P, Nemeth AH, Banka S, Bengani H, Handley M, Freyer E, Ross A, van Heyningen V, Marsh JA, Elmslie F, FitzPatrick DR, A Restricted Repertoire of De Novo Mutations in ITPR1 Cause Gillespie Syndrome with Evidence for Dominant-Negative Effect. Am J Hum Genet. 2016 May 5;98(5):981-92 |
1 | J:34807 Miyata T, Nakajima K, Aruga J, Takahashi S, Ikenaka K, Mikoshiba K, Ogawa M, Distribution of a reeler gene-related antigen in the developing cerebellum: an immunohistochemical study with an allogeneic antibody CR-50 on normal and reeler mice. J Comp Neurol. 1996 Aug 19;372(2):215-28 |
1* | J:53109 Rosemblit N, Moschella MC, Ondriasa E, Gutstein DE, Ondrias K, Marks AR, Intracellular calcium release channel expression during embryogenesis. Dev Biol. 1999 Feb 15;206(2):163-77 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
1 | J:200792 Wang P, Tang M, Gao L, Luo H, Wang G, Ma X, Duan Y, Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development. J Cell Biochem. 2013 Aug;114(8):1852-62 |
Itpr2 inositol 1,4,5-triphosphate receptor 2 (Synonyms: Ip3r2, Itpr5) | |
Results | Reference |
1* | J:79406 Faure AV, Grunwald D, Moutin MJ, Hilly M, Mauger JP, Marty I, De Waard M, Villaz M, Albrieux M, Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex. Eur J Neurosci. 2001 Nov;14(10):1613-22 |
1 | J:200792 Wang P, Tang M, Gao L, Luo H, Wang G, Ma X, Duan Y, Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development. J Cell Biochem. 2013 Aug;114(8):1852-62 |
Itpr3 inositol 1,4,5-triphosphate receptor 3 (Synonyms: Ip3r3, Itpr-3, tf) | |
Results | Reference |
1* | J:79406 Faure AV, Grunwald D, Moutin MJ, Hilly M, Mauger JP, Marty I, De Waard M, Villaz M, Albrieux M, Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex. Eur J Neurosci. 2001 Nov;14(10):1613-22 |
1 | J:311844 Landin MA, Nygard S, Shabestari MG, Babaie E, Reseland JE, Osmundsen H, Mapping the global mRNA transcriptome during development of the murine first molar. Front Genet. 2015;6:47 |
1 | J:200792 Wang P, Tang M, Gao L, Luo H, Wang G, Ma X, Duan Y, Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development. J Cell Biochem. 2013 Aug;114(8):1852-62 |
Ivl involucrin (Synonyms: 1110019C06Rik) | |
Results | Reference |
2* | J:198837 Cui CY, Klar J, Georgii-Heming P, Frojmark AS, Baig SM, Schlessinger D, Dahl N, Frizzled6 deficiency disrupts the differentiation process of nail development. J Invest Dermatol. 2013 Aug;133(8):1990-7 |
1 | J:207252 Drosten M, Lechuga CG, Barbacid M, Ras signaling is essential for skin development. Oncogene. 2014 May 29;33(22):2857-65 |
1 | J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39 |
1 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:83259 Jaubert J, Cheng J, Segre JA, Ectopic expression of kruppel like factor 4 (Klf4) accelerates formation of the epidermal permeability barrier. Development. 2003 Jun;130(12):2767-77 |
1 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
1* | J:234993 Nishiguchi Y, Ohmoto M, Koki J, Enomoto T, Kominami R, Matsumoto I, Hirota J, Bcl11b/Ctip2 is required for development of lingual papillae in mice. Dev Biol. 2016 Aug 1;416(1):98-110 |
1 | J:180027 Restivo G, Nguyen BC, Dziunycz P, Ristorcelli E, Ryan RJ, Ozuysal OY, Di Piazza M, Radtke F, Dixon MJ, Hofbauer GF, Lefort K, Dotto GP, IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes. EMBO J. 2011 Nov 16;30(22):4571-85 |
1 | J:114626 Yu Z, Lin KK, Bhandari A, Spencer JA, Xu X, Wang N, Lu Z, Gill GN, Roop DR, Wertz P, Andersen B, The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Dev Biol. 2006 Nov 1;299(1):122-36 |
2 | J:146244 Zuklys S, Gill J, Keller MP, Hauri-Hohl M, Zhanybekova S, Balciunaite G, Na KJ, Jeker LT, Hafen K, Tsukamoto N, Amagai T, Taketo MM, Krenger W, Hollander GA, Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. J Immunol. 2009 Mar 1;182(5):2997-3007 |
Jade1 jade family PHD finger 1 (Synonyms: D530048A03Rik, mKIAA1807, Phf17) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Jag1 jagged 1 (Synonyms: ABE2, Gsfabe2, Headturner, Htu, Ozz, Serrate-1) | |
Results | Reference |
1* | J:149467 Bosman EA, Quint E, Fuchs H, Hrabe de Angelis M, Steel KP, Catweasel mice: a novel role for Six1 in sensory patch development and a model for branchio-oto-renal syndrome. Dev Biol. 2009 Apr 15;328(2):285-96 |
2 | J:355647 Bugacov H, Der B, Briantseva BM, Guo Q, Kim S, Lindstrom NO, McMahon AP, Dose-dependent responses to canonical Wnt transcriptional complexes in the regulation of mammalian nephron progenitors. Development. 2024 Sep 15;151(18) |
1 | J:173587 Chen W, Jiang H, Wang M, Jin J, Feng S, Bi Y, Wang H, Mao Y, Shou Z, Chen J, Effects of chlorpyrifos exposure on kidney Notch2-Jagged1 pathway of early prenatal embryo. Birth Defects Res B Dev Reprod Toxicol. 2011 Apr;92(2):97-101 |
2 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1 | J:237525 Chung E, Deacon P, Marable S, Shin J, Park JS, Notch signaling promotes nephrogenesis by downregulating Six2. Development. 2016 Nov 01;143(21):3907-3913 |
1 | J:253680 Chung E, Deacon P, Park JS, Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation. Development. 2017 Dec 15;144(24):4530-4539 |
1 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1 | J:142229 Dabdoub A, Puligilla C, Jones JM, Fritzsch B, Cheah KS, Pevny LH, Kelley MW, Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18396-401 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1 | J:139256 Driver EC, Pryor SP, Hill P, Turner J, Ruther U, Biesecker LG, Griffith AJ, Kelley MW, Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans. J Neurosci. 2008 Jul 16;28(29):7350-8 |
1 | J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109 |
1 | J:143603 Esibizione D, Cui CY, Schlessinger D, Candidate EDA targets revealed by expression profiling of primary keratinocytes from Tabby mutant mice. Gene. 2008 Dec 31;427(1-2):42-6 |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1 | J:63320 Favier B, Fliniaux I, Thelu J, Viallet JP, Demarchez M, Jahoda CA, Dhouailly D, Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators. Dev Dyn. 2000 Jul;218(3):426-37 |
2 | J:56675 Felli MP, Maroder M, Mitsiadis TA, Campese AF, Bellavia D, Vacca A, Mann RS, Frati L, Lendahl U, Gulino A, Screpanti I, Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development. Int Immunol. 1999 Jul;11(7):1017-25 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
2* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1 | J:183603 Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A, Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res. 2011 Apr 1;108(7):813-23 |
1 | J:104840 Grishina IB, Kim SY, Ferrara C, Makarenkova HP, Walden PD, BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling. Dev Biol. 2005 Dec 15;288(2):334-47 |
1 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
1 | J:355958 Hartman BH, Durruthy-Durruthy R, Laske RD, Losorelli S, Heller S, Identification and characterization of mouse otic sensory lineage genes. Front Cell Neurosci. 2015;9:79 |
2 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:300508 Hilliard SA, Li Y, Dixon A, El-Dahr SS, Mdm4 controls ureteric bud branching via regulation of p53 activity. Mech Dev. 2020 Sep;163:103616 |
1 | J:166890 Hofmann JJ, Zovein AC, Koh H, Radtke F, Weinmaster G, Iruela-Arispe ML, Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome. Development. 2010 Dec;137(23):4061-72 |
1 | J:82307 Hulander M, Kiernan AE, Blomqvist SR, Carlsson P, Samuelsson EJ, Johansson BR, Steel KP, Enerback S, Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice. Development. 2003 May;130(9):2013-25 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:154589 Jeong HW, Jeon US, Koo BK, Kim WY, Im SK, Shin J, Cho Y, Kim J, Kong YY, Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice. J Clin Invest. 2009 Nov;119(11):3290-300 |
1 | J:126774 Jia J, Lin M, Zhang L, York JP, Zhang P, The notch signaling pathway controls the size of the ocular lens by directly suppressing p57Kip2 expression. Mol Cell Biol. 2007 Oct;27(20):7236-47 |
1* | J:115783 Kiernan AE, Xu J, Gridley T, The Notch ligand JAG1 is required for sensory progenitor development in the mammalian inner ear. PLoS Genet. 2006 Jan;2(1):e4 |
1 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
2* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1* | J:58809 Loomes KM, Underkoffler LA, Morabito J, Gottlieb S, Piccoli DA, Spinner NB, Baldwin HS, Oakey RJ, The expression of Jagged1 in the developing mammalian heart correlates with cardiovascular disease in Alagille syndrome. Hum Mol Genet. 1999 Dec;8(13):2443-9 |
1* | J:67157 McCright B, Gao X, Shen L, Lozier J, Lan Y, Maguire M, Herzlinger D, Weinmaster G, Jiang R, Gridley T, Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development. 2001 Feb;128(4):491-502 |
1 | J:332403 Miller SR, Perera SN, Benito C, Stott SR, Baker CV, Evidence for a Notch1-mediated transition during olfactory ensheathing cell development. J Anat. 2016 Sep;229(3):369-83 |
1* | J:40837 Mitsiadis TA, Henrique D, Thesleff I, Lendahl U, Mouse Serrate-1 (Jagged-1): expression in the developing tooth is regulated by epithelial-mesenchymal interactions and fibroblast growth factor-4. Development. 1997 Apr;124(8):1473-83 |
1 | J:320686 Molina LM, Zhu J, Li Q, Pradhan-Sundd T, Krutsenko Y, Sayed K, Jenkins N, Vats R, Bhushan B, Ko S, Hu S, Poddar M, Singh S, Tao J, Sundd P, Singhi A, Watkins S, Ma X, Benos PV, Feranchak A, Michalopoulos G, Nejak-Bowen K, Watson A, Bell A, Monga SP, Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors. Cell Rep. 2021 Jul 6;36(1):109310 |
1* | J:56415 Morrison A, Hodgetts C, Gossler A, Hrabe de Angelis M, Lewis J, Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear. Mech Dev. 1999 Jun;84(1-2):169-72 |
1 | J:275137 Munro DAD, Wineberg Y, Tarnick J, Vink CS, Li Z, Pridans C, Dzierzak E, Kalisky T, Hohenstein P, Davies JA, Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development. Elife. 2019 Feb 13;8:e43271 |
1 | J:143162 Murata J, Tokunaga A, Okano H, Kubo T, Mapping of notch activation during cochlear development in mice: implications for determination of prosensory domain and cell fate diversification. J Comp Neurol. 2006 Jul 20;497(3):502-18 |
1 | J:309384 Neirijnck Y, Reginensi A, Renkema KY, Massa F, Kozlov VM, Dhib H, Bongers EMHF, Feitz WF, van Eerde AM, Lefebvre V, Knoers NVAM, Tabatabaei M, Schulz H, McNeill H, Schaefer F, Wegner M, Sock E, Schedl A, Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT). Kidney Int. 2018 May;93(5):1142-1153 |
1 | J:198671 Nelson BR, Hodge RD, Bedogni F, Hevner RF, Dynamic interactions between intermediate neurogenic progenitors and radial glia in embryonic mouse neocortex: potential role in Dll1-Notch signaling. J Neurosci. 2013 May 22;33(21):9122-39 |
1 | J:173578 Parker MA, Jiang K, Kempfle JS, Mizutari K, Simmons CL, Bieber R, Adams J, Edge AS, TAK1 Expression in the Cochlea: A Specific Marker for Adult Supporting Cells. J Assoc Res Otolaryngol. 2011 Aug;12(4):471-83 |
1 | J:255143 Rasouly HM, Kumar S, Chan S, Pisarek-Horowitz A, Sharma R, Xi QJ, Nishizaki Y, Higashi Y, Salant DJ, Maas RL, Lu W, Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease. Kidney Int. 2016 Dec;90(6):1262-1273 |
1 | J:286655 Sakamoto S, Tateya T, Omori K, Kageyama R, Id genes are required for morphogenesis and cellular patterning in the developing mammalian cochlea. Dev Biol. 2020 Apr 15;460(2):164-175 |
1 | J:194385 Steffes G, Lorente-Canovas B, Pearson S, Brooker RH, Spiden S, Kiernan AE, Guenet JL, Steel KP, Mutanlallemand (mtl) and Belly Spot and Deafness (bsd) are two new mutations of Lmx1a causing severe cochlear and vestibular defects. PLoS One. 2012;7(11):e51065 |
1 | J:213069 Vanorny DA, Prasasya RD, Chalpe AJ, Kilen SM, Mayo KE, Notch signaling regulates ovarian follicle formation and coordinates follicular growth. Mol Endocrinol. 2014 Apr;28(4):499-511 |
1 | J:236342 Wang W, Jossin Y, Chai G, Lien WH, Tissir F, Goffinet AM, Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun. 2016 Mar 04;7:10936 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:251156 Wen Q, Wang Y, Tang J, Cheng CY, Liu YX, Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development. PLoS One. 2016;11(12):e0167920 |
1 | J:155893 Xu K, Nieuwenhuis E, Cohen BL, Wang W, Canty AJ, Danska JS, Coultas L, Rossant J, Wu MY, Piscione TD, Nagy A, Gossler A, Hicks GG, Hui CC, Henkelman RM, Yu LX, Sled JG, Gridley T, Egan SE, Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis. Am J Physiol Lung Cell Mol Physiol. 2010 Jan;298(1):L45-56 |
1 | J:198224 Zhang S, Loch AJ, Radtke F, Egan SE, Xu K, Jagged1 is the major regulator of Notch-dependent cell fate in proximal airways. Dev Dyn. 2013 Jun;242(6):678-86 |
2 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Jag2 jagged 2 (Synonyms: D12Ggc2e, Serh) | |
Results | Reference |
2 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1 | J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109 |
1 | J:56675 Felli MP, Maroder M, Mitsiadis TA, Campese AF, Bellavia D, Vacca A, Mann RS, Frati L, Lendahl U, Gulino A, Screpanti I, Expression pattern of notch1, 2 and 3 and Jagged1 and 2 in lymphoid and stromal thymus components: distinct ligand-receptor interactions in intrathymic T cell development. Int Immunol. 1999 Jul;11(7):1017-25 |
1* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1 | J:183603 Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A, Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res. 2011 Apr 1;108(7):813-23 |
1 | J:104840 Grishina IB, Kim SY, Ferrara C, Makarenkova HP, Walden PD, BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling. Dev Biol. 2005 Dec 15;288(2):334-47 |
1 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
1* | J:125514 Hartman BH, Hayashi T, Nelson BR, Bermingham-McDonogh O, Reh TA, Dll3 is expressed in developing hair cells in the mammalian cochlea. Dev Dyn. 2007 Oct;236(10):2875-83 |
1 | J:137800 Jin JZ, Li Q, Higashi Y, Darling DS, Ding J, Analysis of Zfhx1a mutant mice reveals palatal shelf contact-independent medial edge epithelial differentiation during palate fusion. Cell Tissue Res. 2008 Jul;333(1):29-38 |
1 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
1 | J:225061 Kouskoura T, Kozlova A, Alexiou M, Blumer S, Zouvelou V, Katsaros C, Chiquet M, Mitsiadis TA, Graf D, The etiology of cleft palate formation in BMP7-deficient mice. PLoS One. 2013;8(3):e59463 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1* | J:67157 McCright B, Gao X, Shen L, Lozier J, Lan Y, Maguire M, Herzlinger D, Weinmaster G, Jiang R, Gridley T, Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development. 2001 Feb;128(4):491-502 |
1 | J:332403 Miller SR, Perera SN, Benito C, Stott SR, Baker CV, Evidence for a Notch1-mediated transition during olfactory ensheathing cell development. J Anat. 2016 Sep;229(3):369-83 |
1 | J:339608 Mitsiadis TA, Pagella P, Capellini TD, Smith MM, The Notch-mediated circuitry in the evolution and generation of new cell lineages: the tooth model. Cell Mol Life Sci. 2023 Jun 18;80(7):182 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
1* | J:294646 Stupnikov MR, Yang Y, Mori M, Lu J, Cardoso WV, Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. Elife. 2019 Oct 21;8:e50487 |
1* | J:46031 Valsecchi C, Ghezzi C, Ballabio A, Rugarli EI, JAGGED2: a putative Notch ligand expressed in the apical ectodermal ridge and in sites of epithelial-mesenchymal interactions. Mech Dev. 1997 Dec;69(1-2):203-7 |
1 | J:213069 Vanorny DA, Prasasya RD, Chalpe AJ, Kilen SM, Mayo KE, Notch signaling regulates ovarian follicle formation and coordinates follicular growth. Mol Endocrinol. 2014 Apr;28(4):499-511 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Jak1 Janus kinase 1 (Synonyms: BAP004, C130039L05Rik) | |
Results | Reference |
1* | J:91730 Verma-Kurvari S, Parada LF, Identification of tyrosine kinases expressed in the male mouse gubernaculum during development. Dev Dyn. 2004 Aug;230(4):660-5 |
Jam2 junction adhesion molecule 2 (Synonyms: 2410030G21Rik, 2410167M24Rik, JAM-2, Jcam2, VE-JAM) | |
Results | Reference |
1 | J:112136 Sakaguchi T, Nishimoto M, Miyagi S, Iwama A, Morita Y, Iwamori N, Nakauchi H, Kiyonari H, Muramatsu M, Okuda A, Putative 'stemness' gene jam-B is not required for maintenance of stem cell state in embryonic, neural, or hematopoietic stem cells. Mol Cell Biol. 2006 Sep;26(17):6557-70 |
1 | J:318348 Stelzer IA, Mori M, DeMayo F, Lydon J, Arck PC, Solano ME, Differential mouse-strain specific expression of Junctional Adhesion Molecule (JAM)-B in placental structures. Cell Adh Migr. 2016 Mar 3;10(1-2):2-17 |
Jam3 junction adhesion molecule 3 (Synonyms: 1110002N23Rik, JAM-3, JAM-C, Jcam3) | |
Results | Reference |
1 | J:112136 Sakaguchi T, Nishimoto M, Miyagi S, Iwama A, Morita Y, Iwamori N, Nakauchi H, Kiyonari H, Muramatsu M, Okuda A, Putative 'stemness' gene jam-B is not required for maintenance of stem cell state in embryonic, neural, or hematopoietic stem cells. Mol Cell Biol. 2006 Sep;26(17):6557-70 |
1 | J:343554 Sun Q, Li J, Ma J, Zheng Y, Ju R, Li X, Ren X, Huang L, Chen R, Tan X, Luo L, JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development. Invest Ophthalmol Vis Sci. 2023 Dec 1;64(15):15 |
Jarid2 jumonji and AT-rich interaction domain containing 2 (Synonyms: Jmj, jumonji) | |
Results | Reference |
1* | J:85152 Anzai H, Kamiya A, Shirato H, Takeuchi T, Miyajima A, Impaired differentiation of fetal hepatocytes in homozygous jumonji mice. Mech Dev. 2003 Jul;120(7):791-800 |
1 | J:280323 Cho E, Kang H, Kang DK, Lee Y, Myocardial-specific ablation of Jumonji and AT-rich interaction domain-containing 2 (Jarid2) leads to dilated cardiomyopathy in mice. J Biol Chem. 2019 Mar 29;294(13):4981-4996 |
1 | J:267108 Cho E, Mysliwiec MR, Carlson CD, Ansari A, Schwartz RJ, Lee Y, Cardiac-specific developmental and epigenetic functions of Jarid2 during embryonic development. J Biol Chem. 2018 Jul 27;293(30):11659-11673 |
1 | J:63359 Lee Y, Song AJ, Baker R, Micales B, Conway SJ, Lyons GE, Jumonji, a nuclear protein that is necessary for normal heart development [see comments]. Circ Res. 2000 May 12;86(9):932-8 |
1 | J:109567 Shen WB, Plachez C, Mongi AS, Richards LJ, Identification of candidate genes at the corticoseptal boundary during development. Gene Expr Patterns. 2006 Jun;6(5):471-81 |
1 | J:25641 Takeuchi T, Yamazaki Y, Katoh-Fukui Y, Tsuchiya R, Kondo S, Motoyama J, Higashinakagawa T, Gene trap capture of a novel mouse gene, jumonji, required for neural tube formation. Genes Dev. 1995 May 15;9(10):1211-22 |
1 | J:267650 Toyoda M, Shirato H, Nakajima K, Kojima M, Takahashi M, Kubota M, Suzuki-Migishima R, Motegi Y, Yokoyama M, Takeuchi T, jumonji downregulates cardiac cell proliferation by repressing cyclin D1 expression. Dev Cell. 2003 Jul;5(1):85-97 |
Jmjd1c jumonji domain containing 1C (Synonyms: 5430433L24Rik, D630035I23Rik, TRIP8) | |
Results | Reference |
1 | J:262221 Nakajima R, Okano H, Noce T, JMJD1C Exhibits Multiple Functions in Epigenetic Regulation during Spermatogenesis. PLoS One. 2016;11(9):e0163466 |
Jmjd6 jumonji domain containing 6 (Synonyms: 5730436I23Rik, mKIAA0585, PSR, PtdSerR, Ptdsr) | |
Results | Reference |
1* | J:86771 Li MO, Sarkisian MR, Mehal WZ, Rakic P, Flavell RA, Phosphatidylserine receptor is required for clearance of apoptotic cells. Science. 2003 Nov 28;302(5650):1560-3 |
Jph2 junctophilin 2 (Synonyms: 1110002E14Rik, JP-2) | |
Results | Reference |
2* | J:93830 Minamisawa S, Oshikawa J, Takeshima H, Hoshijima M, Wang Y, Chien KR, Ishikawa Y, Matsuoka R, Junctophilin type 2 is associated with caveolin-3 and is down-regulated in the hypertrophic and dilated cardiomyopathies. Biochem Biophys Res Commun. 2004 Dec 17;325(3):852-856 |
Jun jun proto-oncogene (Synonyms: c-jun, Junc) | |
Results | Reference |
1* | J:23980 Carrasco D, Bravo R, Tissue-specific expression of the fos-related transcription factor fra-2 during mouse development. Oncogene. 1995 Mar 16;10(6):1069-79 |
1* | J:317552 Casey SC, Blumberg B, The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver. Mol Endocrinol. 2012 Jun;26(6):916-25 |
1* | J:231595 Gurdziel K, Vogt KR, Walton KD, Schneider GK, Gumucio DL, Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun. Dev Dyn. 2016 May;245(5):614-26 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:171254 Matsumoto A, Onoyama I, Sunabori T, Kageyama R, Okano H, Nakayama KI, Fbxw7-dependent Degradation of Notch Is Required for Control of 'Stemness' and Neuronal-Glial Differentiation in Neural Stem Cells. J Biol Chem. 2011 Apr 15;286(15):13754-64 |
1 | J:153617 O'Shaughnessy RF, Welti JC, Sully K, Byrne C, Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development. Development. 2009 Oct;136(20):3423-31 |
1 | J:93433 Weston CR, Wong A, Hall JP, Goad ME, Flavell RA, Davis RJ, The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis. Proc Natl Acad Sci U S A. 2004 Oct 28;101(39):14114-9 |
1 | J:199582 Youssef G, Gerner L, Naeem AS, Ralph O, Ono M, O'Neill CA, O'Shaughnessy RF, Rab3Gap1 mediates exocytosis of Claudin-1 and tight junction formation during epidermal barrier acquisition. Dev Biol. 2013 Aug 15;380(2):274-85 |
1 | J:125580 Zhang L, Deng M, Kao CW, Kao WW, Xia Y, MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis. Mol Vis. 2003 Nov 3;9:584-93 |
Junb jun B proto-oncogene | |
Results | Reference |
1* | J:23980 Carrasco D, Bravo R, Tissue-specific expression of the fos-related transcription factor fra-2 during mouse development. Oncogene. 1995 Mar 16;10(6):1069-79 |
Jund jun D proto-oncogene | |
Results | Reference |
1* | J:23980 Carrasco D, Bravo R, Tissue-specific expression of the fos-related transcription factor fra-2 during mouse development. Oncogene. 1995 Mar 16;10(6):1069-79 |
Jup junction plakoglobin (Synonyms: Ctnng, D930025P04Rik, gamma-catenin, PG, plakoglobin) | |
Results | Reference |
1* | J:48097 Cifuentes-Diaz C, Goudou D, Mege RM, Velasco E, Nicolet M, Herrenknecht K, Rubin L, Rieger F, Distinct location and prevalence of alpha-, beta-catenins and gamma-catenin/plakoglobin in developing and denervated skeletal muscle. Cell Adhes Commun. 1998 Mar;5(2):161-76 |
1* | J:47740 Fausser JL, Schlepp O, Aberdam D, Meneguzzi G, Ruch JV, Lesot H, Localization of antigens associated with adherens junctions, desmosomes, and hemidesmosomes during murine molar morphogenesis. Differentiation. 1998 May;63(1):1-11 |
Kat2a K(lysine) acetyltransferase 2A (Synonyms: 1110051E14Rik, Gcn5, Gcn5l2, PCAF-B/GCN5) | |
Results | Reference |
1 | J:65002 Xu W, Edmondson DG, Evrard YA, Wakamiya M, Behringer RR, Roth SY, Loss of gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development. Nat Genet. 2000 Oct;26(2):229-32 |
Kat2b K(lysine) acetyltransferase 2B (Synonyms: A930006P13Rik, Pcaf) | |
Results | Reference |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1 | J:65002 Xu W, Edmondson DG, Evrard YA, Wakamiya M, Behringer RR, Roth SY, Loss of gcn5l2 leads to increased apoptosis and mesodermal defects during mouse development. Nat Genet. 2000 Oct;26(2):229-32 |
Kat6b K(lysine) acetyltransferase 6B (Synonyms: B130044K16Rik, monocytic leukemia, Morf, Myst4, qkf, querkopf) | |
Results | Reference |
1* | J:62161 Thomas T, Voss AK, Chowdhury K, Gruss P, Querkopf, a MYST family histone acetyltransferase, is required for normal cerebral cortex development. Development. 2000 Jun;127(12):2537-48 |
Kat7 K(lysine) acetyltransferase 7 (Synonyms: Hbo1, Hboa, MGC:56758, Myst2) | |
Results | Reference |
1 | J:224155 You L, Yan K, Zhou J, Zhao H, Bertos NR, Park M, Wang E, Yang XJ, The lysine acetyltransferase activator Brpf1 governs dentate gyrus development through neural stem cells and progenitors. PLoS Genet. 2015 Mar;11(3):e1005034 |
Katnal2 katanin p60 subunit A-like 2 (Synonyms: 3110023G01Rik, 4933439B08Rik) | |
Results | Reference |
1* | J:359964 DeSpenza T Jr, Singh A, Allington G, Zhao S, Lee J, Kiziltug E, Prina ML, Desmet N, Dang HQ, Fields J, Nelson-Williams C, Zhang J, Mekbib KY, Dennis E, Mehta NH, Duy PQ, Shimelis H, Walsh LK, Marlier A, Deniz E, Lake EMR, Constable RT, Hoffman EJ, Lifton RP, Gulledge A, Fiering S, Moreno-De-Luca A, Haider S, Alper SL, Jin SC, Kahle KT, Luikart BW, Pathogenic variants in autism gene KATNAL2 cause hydrocephalus and disrupt neuronal connectivity by impairing ciliary microtubule dynamics. Proc Natl Acad Sci U S A. 2024 Jul 2;121(27):e2314702121 |
Kazald1 Kazal-type serine peptidase inhibitor domain 1 (Synonyms: Bono1, Igfbp-rp10) | |
Results | Reference |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Kbtbd11 kelch repeat and BTB (POZ) domain containing 11 (Synonyms: 2900016B01Rik, 4930465M17Rik) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Kcna1 potassium voltage-gated channel, shaker-related subfamily, member 1 (Synonyms: Kv1.1, MBK1, mceph, Mk-1, mouse brain potassium channel protein-1, Shak) | |
Results | Reference |
1* | J:48807 Hallows JL, Tempel BL, Expression of Kv1.1, a Shaker-like potassium channel, is temporally regulated in embryonic neurons and glia. J Neurosci. 1998 Aug 1;18(15):5682-91 |
Kcna2 potassium voltage-gated channel, shaker-related subfamily, member 2 (Synonyms: Akr6a4, Kca1-2, Kv1.2, Mk-2) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Kcna5 potassium voltage-gated channel, shaker-related subfamily, member 5 (Synonyms: Kv1.5) | |
Results | Reference |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
Kcna10 potassium voltage-gated channel, shaker-related subfamily, member 10 (Synonyms: Kcna8, Kv1.8) | |
Results | Reference |
1* | J:183945 Carlisle FA, Steel KP, Lewis MA, Specific expression of Kcna10, Pxn and Odf2 in the organ of Corti. Gene Expr Patterns. 2012 May;12(5-6):172-9 |
Kcnc1 potassium voltage gated channel, Shaw-related subfamily, member 1 (Synonyms: C230009H10Rik, Kcr2-1, KShIIIB, Kv3.1, KV4, NGK2, Shaw) | |
Results | Reference |
1 | J:68046 Demolombe S, Franco D, de Boer P, Kuperschmidt S, Roden D, Pereon Y, Jarry A, Moorman AF, Escande D, Differential expression of KvLQT1 and its regulator IsK in mouse epithelia. Am J Physiol Cell Physiol. 2001 Feb;280(2):C359-72 |
Kcnd2 potassium voltage-gated channel, Shal-related family, member 2 (Synonyms: Kv4.2, mKIAA1044) | |
Results | Reference |
1* | J:243480 Gomez-Herreros F, Schuurs-Hoeijmakers JH, McCormack M, Greally MT, Rulten S, Romero-Granados R, Counihan TJ, Chaila E, Conroy J, Ennis S, Delanty N, Cortes-Ledesma F, de Brouwer AP, Cavalleri GL, El-Khamisy SF, de Vries BB, Caldecott KW, TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function. Nat Genet. 2014 May;46(5):516-21 |
1* | J:114661 Lyu YL, Lin CP, Azarova AM, Cai L, Wang JC, Liu LF, Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Mol Cell Biol. 2006 Nov;26(21):7929-41 |
Kcne1 potassium voltage-gated channel, Isk-related subfamily, member 1 (Synonyms: Isk, MinK, nmf190) | |
Results | Reference |
1* | J:74171 Franco D, Demolombe S, Kupershmidt S, Dumaine R, Dominguez JN, Roden D, Antzelevitch C, Escande D, Moorman AF, Divergent expression of delayed rectifier K(+) channel subunits during mouse heart development. Cardiovasc Res. 2001 Oct;52(1):65-75 |
1 | J:122971 Moskowitz IP, Kim JB, Moore ML, Wolf CM, Peterson MA, Shendure J, Nobrega MA, Yokota Y, Berul C, Izumo S, Seidman JG, Seidman CE, A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development. Cell. 2007 Jun 29;129(7):1365-76 |
Kcne3 potassium voltage-gated channel, Isk-related subfamily, gene 3 (Synonyms: 2210017H05Rik, MiRP2) | |
Results | Reference |
1 | J:174181 de Castro MP, Aranega A, Franco D, Protein distribution of Kcnq1, Kcnh2, and Kcne3 potassium channel subunits during mouse embryonic development. Anat Rec A Discov Mol Cell Evol Biol. 2006 Mar;288(3):304-15 |
1* | J:74171 Franco D, Demolombe S, Kupershmidt S, Dumaine R, Dominguez JN, Roden D, Antzelevitch C, Escande D, Moorman AF, Divergent expression of delayed rectifier K(+) channel subunits during mouse heart development. Cardiovasc Res. 2001 Oct;52(1):65-75 |
Kcnh2 potassium voltage-gated channel, subfamily H (eag-related), member 2 (Synonyms: ERG1, ether a go-go related, LQT, Lqt2, M-erg, merg1a, merg1b) | |
Results | Reference |
1 | J:174181 de Castro MP, Aranega A, Franco D, Protein distribution of Kcnq1, Kcnh2, and Kcne3 potassium channel subunits during mouse embryonic development. Anat Rec A Discov Mol Cell Evol Biol. 2006 Mar;288(3):304-15 |
1* | J:74171 Franco D, Demolombe S, Kupershmidt S, Dumaine R, Dominguez JN, Roden D, Antzelevitch C, Escande D, Moorman AF, Divergent expression of delayed rectifier K(+) channel subunits during mouse heart development. Cardiovasc Res. 2001 Oct;52(1):65-75 |
Kcnh3 potassium voltage-gated channel, subfamily H (eag-related), member 3 (Synonyms: C030044P22Rik, Elk2, ether a go-go like, Melk2) | |
Results | Reference |
2* | J:302089 Vezzali R, Weise SC, Hellbach N, Machado V, Heidrich S, Vogel T, The FOXG1/FOXO/SMAD network balances proliferation and differentiation of cortical progenitors and activates Kcnh3 expression in mature neurons. Oncotarget. 2016 Jun 21;7(25):37436-37455 |
Kcnh5 potassium voltage-gated channel, subfamily H (eag-related), member 5 | |
Results | Reference |
1 | J:186629 Huang X, Dubuc AM, Hashizume R, Berg J, He Y, Wang J, Chiang C, Cooper MK, Northcott PA, Taylor MD, Barnes MJ, Tihan T, Chen J, Hackett CS, Weiss WA, James CD, Rowitch DH, Shuman MA, Jan YN, Jan LY, Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes Dev. 2012 Aug 15;26(16):1780-96 |
Kcnh7 potassium voltage-gated channel, subfamily H (eag-related), member 7 (Synonyms: 9330137I11Rik, erg3, Kv11.3) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Kcnip1 Kv channel-interacting protein 1 (Synonyms: 2900046L02Rik, 3202002F18Rik, KCHIP1) | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Kcnip3 Kv channel interacting protein 3, calsenilin (Synonyms: 4933407H12Rik, Csen, DREAM, KChIP3, R74849) | |
Results | Reference |
1* | J:67258 Spreafico F, Barski JJ, Farina C, Meyer M, Mouse dream/calsenilin/kchip3: gene structure, coding potential, and expression. Mol Cell Neurosci. 2001 Jan;17(1):1-16 |
Kcnj2 potassium inwardly-rectifying channel, subfamily J, member 2 (Synonyms: IRK1, Kcnf1, Kir2.1) | |
Results | Reference |
1 | J:250657 Greulich F, Trowe MO, Leffler A, Stoetzer C, Farin HF, Kispert A, Misexpression of Tbx18 in cardiac chambers of fetal mice interferes with chamber-specific developmental programs but does not induce a pacemaker-like gene signature. J Mol Cell Cardiol. 2016 Aug;97:140-9 |
Kcnj3 potassium inwardly-rectifying channel, subfamily J, member 3 (Synonyms: GIRK1, Kcnf3, Kir3.1) | |
Results | Reference |
1 | J:250657 Greulich F, Trowe MO, Leffler A, Stoetzer C, Farin HF, Kispert A, Misexpression of Tbx18 in cardiac chambers of fetal mice interferes with chamber-specific developmental programs but does not induce a pacemaker-like gene signature. J Mol Cell Cardiol. 2016 Aug;97:140-9 |
Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 (Synonyms: GIRK2, KCNJ7, Kir3.2) | |
Results | Reference |
1 | J:41890 Wei J, Dlouhy SR, Bayer S, Piva R, Verina T, Wang Y, Feng Y , Dupree B , Hodes ME , Ghetti B, In situ hybridization analysis of Girk2 expression in the developing central nervous system in normal and weaver mice. J Neuropathol Exp Neurol. 1997 Jul;56(7):762-71 |
Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 (Synonyms: Kir6.2) | |
Results | Reference |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
Kcnj13 potassium inwardly-rectifying channel, subfamily J, member 13 | |
Results | Reference |
1* | J:227219 Villanueva S, Burgos J, Lopez-Cayuqueo KI, Lai KM, Valenzuela DM, Cid LP, Sepulveda FV, Cleft Palate, Moderate Lung Developmental Retardation and Early Postnatal Lethality in Mice Deficient in the Kir7.1 Inwardly Rectifying K+ Channel. PLoS One. 2015;10(9):e0139284 |
1 | J:266389 Yin W, Kim HT, Wang S, Gunawan F, Wang L, Kishimoto K, Zhong H, Roman D, Preussner J, Guenther S, Graef V, Buettner C, Grohmann B, Looso M, Morimoto M, Mardon G, Offermanns S, Stainier DYR, The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis. Nat Commun. 2018 Jul 19;9(1):2815 |
Kcnma1 potassium large conductance calcium-activated channel, subfamily M, alpha member 1 (Synonyms: 5730414M22Rik, BKCa, BK channel alpha subunit, MaxiK, mSlo1, Slo, Slo1) | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Kcnq1 potassium voltage-gated channel, subfamily Q, member 1 (Synonyms: Kcna9, KVLQT1) | |
Results | Reference |
1 | J:174181 de Castro MP, Aranega A, Franco D, Protein distribution of Kcnq1, Kcnh2, and Kcne3 potassium channel subunits during mouse embryonic development. Anat Rec A Discov Mol Cell Evol Biol. 2006 Mar;288(3):304-15 |
1 | J:68046 Demolombe S, Franco D, de Boer P, Kuperschmidt S, Roden D, Pereon Y, Jarry A, Moorman AF, Escande D, Differential expression of KvLQT1 and its regulator IsK in mouse epithelia. Am J Physiol Cell Physiol. 2001 Feb;280(2):C359-72 |
1 | J:79882 Fitzpatrick GV, Soloway PD, Higgins MJ, Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1. Nat Genet. 2002 Nov;32(3):426-31 |
2* | J:74171 Franco D, Demolombe S, Kupershmidt S, Dumaine R, Dominguez JN, Roden D, Antzelevitch C, Escande D, Moorman AF, Divergent expression of delayed rectifier K(+) channel subunits during mouse heart development. Cardiovasc Res. 2001 Oct;52(1):65-75 |
2* | J:46363 Gould TD, Pfeifer K, Imprinting of mouse Kvlqt1 is developmentally regulated. Hum Mol Genet. 1998 Mar;7(3):483-7 |
1* | J:190449 Korostowski L, Sedlak N, Engel N, The Kcnq1ot1 long non-coding RNA affects chromatin conformation and expression of Kcnq1, but does not regulate its imprinting in the developing heart. PLoS Genet. 2012 Sep;8(9):e1002956 |
1 | J:347618 Qin T, So KKH, Hui CC, Sham MH, Ptch1 is essential for cochlear marginal cell differentiation and stria vascularis formation. Cell Rep. 2024 Apr 23;43(4):114083 |
Kcnq1ot1 KCNQ1 overlapping transcript 1 (Synonyms: Kvlqt1-as, Lit1, Tssc8) | |
Results | Reference |
1* | J:190449 Korostowski L, Sedlak N, Engel N, The Kcnq1ot1 long non-coding RNA affects chromatin conformation and expression of Kcnq1, but does not regulate its imprinting in the developing heart. PLoS Genet. 2012 Sep;8(9):e1002956 |
1* | J:356303 Zhao Y, Zheng D, Cvekl A, A comprehensive spatial-temporal transcriptomic analysis of differentiating nascent mouse lens epithelial and fiber cells. Exp Eye Res. 2018 Oct;175:56-72 |
Kcnq2 potassium voltage-gated channel, subfamily Q, member 2 (Synonyms: KQT2, Nmf134) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Kcnq4 potassium voltage-gated channel, subfamily Q, member 4 | |
Results | Reference |
1* | J:342400 Beisel KW, Rocha-Sanchez SM, Morris KA, Nie L, Feng F, Kachar B, Yamoah EN, Fritzsch B, Differential expression of KCNQ4 in inner hair cells and sensory neurons is the basis of progressive high-frequency hearing loss. J Neurosci. 2005 Oct 5;25(40):9285-93 |
1* | J:118633 Rocha-Sanchez SM, Morris KA, Kachar B, Nichols D, Fritzsch B, Beisel KW, Developmental expression of Kcnq4 in vestibular neurons and neurosensory epithelia. Brain Res. 2007 Mar 30;1139:117-25 |
Kcp kielin/chordin-like protein (Synonyms: Crim2, KCP, LOC333088) | |
Results | Reference |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
Kctd1 potassium channel tetramerisation domain containing 1 (Synonyms: 4933402K10Rik) | |
Results | Reference |
1* | J:303715 Woodruff ED, Gutierrez GC, Van Otterloo E, Williams T, Cohn MJ, Anomalous incisor morphology indicates tissue-specific roles for Tfap2a and Tfap2b in tooth development. Dev Biol. 2021 Apr;472:67-74 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Kctd8 potassium channel tetramerisation domain containing 8 (Synonyms: A730087N02Rik) | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Kctd10 potassium channel tetramerisation domain containing 10 | |
Results | Reference |
1 | J:346633 Cheng J, Wang Z, Tang M, Zhang W, Li G, Tan S, Mu C, Hu M, Zhang D, Jia X, Wen Y, Guo H, Xu D, Liu L, Li J, Xia K, Li F, Duan R, Xu Z, Yuan L, KCTD10 regulates brain development by destabilizing brain disorder-associated protein KCTD13. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2315707121 |
Kctd11 potassium channel tetramerisation domain containing 11 (Synonyms: Ren) | |
Results | Reference |
1* | J:78799 Gallo R, Zazzeroni F, Alesse E, Mincione C, Borello U, Buanne P, D'Eugenio R, Mackay AR, Argenti B, Gradini R, Russo MA, Maroder M, Cossu G, Frati L, Screpanti I, Gulino A, Ren: a novel, developmentally regulated gene that promotes neural cell differentiation. J Cell Biol. 2002 Aug 19;158(4):731-40 |
Kctd12 potassium channel tetramerisation domain containing 12 (Synonyms: Pfet1, Pfetin) | |
Results | Reference |
1* | J:93172 Resendes BL, Kuo SF, Robertson NG, Giersch AB, Honrubia D, Ohara O, Adams JC, Morton CC, Isolation from cochlea of a novel human intronless gene with predominant fetal expression. J Assoc Res Otolaryngol. 2004 Jun;5(2):185-202 |
Kctd13 potassium channel tetramerisation domain containing 13 (Synonyms: 1500003N18Rik, Pdip1, Poldip1) | |
Results | Reference |
1 | J:346633 Cheng J, Wang Z, Tang M, Zhang W, Li G, Tan S, Mu C, Hu M, Zhang D, Jia X, Wen Y, Guo H, Xu D, Liu L, Li J, Xia K, Li F, Duan R, Xu Z, Yuan L, KCTD10 regulates brain development by destabilizing brain disorder-associated protein KCTD13. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2315707121 |
Kctd17 potassium channel tetramerisation domain containing 17 (Synonyms: 2900008M13Rik) | |
Results | Reference |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
Kctd19 potassium channel tetramerisation domain containing 19 (Synonyms: 4922504H04Rik) | |
Results | Reference |
2 | J:307864 Horisawa-Takada Y, Kodera C, Takemoto K, Sakashita A, Horisawa K, Maeda R, Shimada R, Usuki S, Fujimura S, Tani N, Matsuura K, Akiyama T, Suzuki A, Niwa H, Tachibana M, Ohba T, Katabuchi H, Namekawa SH, Araki K, Ishiguro KI, Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis. Nat Commun. 2021 Jun 1;12(1):3184 |
1* | J:306305 Oura S, Koyano T, Kodera C, Horisawa-Takada Y, Matsuyama M, Ishiguro KI, Ikawa M, KCTD19 and its associated protein ZFP541 are independently essential for meiosis in male mice. PLoS Genet. 2021 May;17(5):e1009412 |
Kdf1 keratinocyte differentiation factor 1 (Synonyms: 1810019J16Rik) | |
Results | Reference |
1* | J:203995 Lee S, Kong Y, Weatherbee SD, Forward genetics identifies Kdf1/1810019J16Rik as an essential regulator of the proliferation-differentiation decision in epidermal progenitor cells. Dev Biol. 2013 Nov 15;383(2):201-13 |
Kdm1a lysine (K)-specific demethylase 1A (Synonyms: 1810043O07Rik, Aof2, Kdm1, LSD1, mKIAA0601) | |
Results | Reference |
1 | J:346895 Guo P, Lim RC, Rajawasam K, Trinh T, Sun H, Zhang H, A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis. Elife. 2024 Feb 12;13 |
2 | J:344312 Liu H, Zhou R, Li S, Dong J, Fang Y, Luo Y, Su H, Lai B, Liang L, Zhang D, Zhang Y, Shyy JY, Zhou B, Yuan Z, Wang Y, Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development. iScience. 2024 Jan 19;27(1):108722 |
2* | J:359190 Nagai M, Porter RS, Miyasato M, Wang A, Gavilan CM, Hughes ED, Wu MC, Saunders TL, Iwase S, Neuronal splicing of the unmethylated histone H3K4 reader, PHF21A, prevents excessive synaptogenesis. J Biol Chem. 2024 Nov;300(11):107881 |
1* | J:271628 Nagamori I, Kobayashi H, Nishimura T, Yamagishi R, Katahira J, Kuramochi-Miyagawa S, Kono T, Nakano T, Relationship between PIWIL4-Mediated H3K4me2 Demethylation and piRNA-Dependent DNA Methylation. Cell Rep. 2018 Oct 9;25(2):350-356 |
1 | J:361726 Porter RS, An S, Gavilan MC, Nagai M, Murata-Nakamura Y, Zhou B, Bonefas KM, Dionne O, Manuel JM, St-Germain J, Gascon S, Kim J, Browning L, Laurent B, Cho US, Iwase S, Coordinated neuron-specific splicing events restrict nucleosome engagement of the LSD1 histone demethylase complex. Cell Rep. 2025 Jan 28;44(1):115213 |
1* | J:317374 Zhang M, Lu Q, Miller AH, Barnthouse NC, Wang J, Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage. Int J Biochem Cell Biol. 2016 Mar;72:125-134 |
Kdm2a lysine (K)-specific demethylase 2A (Synonyms: 5530401A10Rik, Cxxc8, Fbl7, Fbxl11, Gm4560, Jhdm1a, lalina) | |
Results | Reference |
1 | J:171291 Fukuda T, Tokunaga A, Sakamoto R, Yoshida N, Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly. Mol Cell Neurosci. 2011 Mar;46(3):614-24 |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Kdm2b lysine (K)-specific demethylase 2B (Synonyms: Cxxc2, Fbxl10, Jhdm1b, mKIAA3014) | |
Results | Reference |
1 | J:171291 Fukuda T, Tokunaga A, Sakamoto R, Yoshida N, Fbxl10/Kdm2b deficiency accelerates neural progenitor cell death and leads to exencephaly. Mol Cell Neurosci. 2011 Mar;46(3):614-24 |
2* | J:297829 Li W, Shen W, Zhang B, Tian K, Li Y, Mu L, Luo Z, Zhong X, Wu X, Liu Y, Zhou Y, Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b. Protein Cell. 2020 Mar;11(3):161-186 |
1 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
1 | J:194493 Tzatsos A, Paskaleva P, Ferrari F, Deshpande V, Stoykova S, Contino G, Wong KK, Lan F, Trojer P, Park PJ, Bardeesy N, KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs. J Clin Invest. 2013 Feb;123(2):727-39 |
1 | J:341689 Zhang B, Zhao C, Shen W, Li W, Zheng Y, Kong X, Wang J, Wu X, Zeng T, Liu Y, Zhou Y, KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors. Nat Commun. 2023 Oct 14;14(1):6489 |
Kdm3a lysine (K)-specific demethylase 3A (Synonyms: 1700105C21Rik, C230043E16Rik, Jmjd1, Jmjd1a, mKIAA0742, Tsga) | |
Results | Reference |
1 | J:142786 Lockman K, Taylor JM, Mack CP, The histone demethylase, Jmjd1a, interacts with the myocardin factors to regulate SMC differentiation marker gene expression. Circ Res. 2007 Dec 7;101(12):e115-23 |
Kdm5a lysine demethylase 5A (Synonyms: Jarid1a, MGC:11659, Rbbp2, RBP2) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Kdm5b lysine demethylase 5B (Synonyms: 2010009J12Rik, 2210016I17Rik, D1Ertd202e, Jarid1b, Plu1, PLU-1, Rb-Bp2) | |
Results | Reference |
1* | J:271628 Nagamori I, Kobayashi H, Nishimura T, Yamagishi R, Katahira J, Kuramochi-Miyagawa S, Kono T, Nakano T, Relationship between PIWIL4-Mediated H3K4me2 Demethylation and piRNA-Dependent DNA Methylation. Cell Rep. 2018 Oct 9;25(2):350-356 |
Kdm5d lysine demethylase 5D (Synonyms: HY, Jarid1d, Smcy) | |
Results | Reference |
1* | J:74092 Eriksson A, Nordqvist K, Protocol for using signal peptide differential display and representational difference analysis to isolate differentially expressed cDNAs from fetal mouse brain. Brain Res Brain Res Protoc. 2001 Feb;6(3):119-28 |
1 | J:205146 Praktiknjo SD, Llamas B, Scott-Boyer MP, Picard S, Robert F, Langlais D, Haibe-Kains B, Faubert D, Silversides DW, Deschepper CF, Novel effects of chromosome Y on cardiac regulation, chromatin remodeling, and neonatal programming in male mice. Endocrinology. 2013 Dec;154(12):4746-56 |
Kdm6a lysine (K)-specific demethylase 6A (Synonyms: Utx) | |
Results | Reference |
1 | J:312817 Lei X, Jiao J, UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling. Stem Cell Reports. 2018 Apr 10;10(4):1193-1207 |
1 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
Kdm6b KDM1 lysine (K)-specific demethylase 6B (Synonyms: Jmjd3, mKIAA0346) | |
Results | Reference |
2* | J:196346 Burgold T, Voituron N, Caganova M, Tripathi PP, Menuet C, Tusi BK, Spreafico F, Bevengut M, Gestreau C, Buontempo S, Simeone A, Kruidenier L, Natoli G, Casola S, Hilaire G, Testa G, The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival. Cell Rep. 2012 Nov 29;2(5):1244-58 |
1 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1 | J:242516 Sessa A, Ciabatti E, Drechsel D, Massimino L, Colasante G, Giannelli S, Satoh T, Akira S, Guillemot F, Broccoli V, The Tbr2 Molecular Network Controls Cortical Neuronal Differentiation Through Complementary Genetic and Epigenetic Pathways. Cereb Cortex. 2017 Jun 01;27(6):3378-3396 |
1* | J:267242 Shi X, Zhang Z, Zhan X, Cao M, Satoh T, Akira S, Shpargel K, Magnuson T, Li Q, Wang R, Wang C, Ge K, Wu J, An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth. Nat Commun. 2014 Nov 5;5:5425 |
Kdr kinase insert domain protein receptor (Synonyms: Flk-1, Flk1, orv, vascular endothelial growth factor receptor- 2, VEGFR-2, VEGFR2, VEGF receptor-2) | |
Results | Reference |
1* | J:151060 Ahlbrecht K, Schmitz J, Seay U, Schwarz C, Mittnacht-Kraus R, Gaumann A, Haberberger RV, Herold S, Breier G, Grimminger F, Seeger W, Voswinckel R, Spatiotemporal expression of flk-1 in pulmonary epithelial cells during lung development. Am J Respir Cell Mol Biol. 2008 Aug;39(2):163-70 |
1* | J:69389 Ayadi A, Suelves M, Dolle P, Wasylyk B, Net, an Ets ternary complex transcription factor, is expressed in sites of vasculogenesis, angiogenesis, and chondrogenesis during mouse development. Mech Dev. 2001 Apr;102(1-2):205-8 |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1 | J:237001 Duan X, Bradbury SR, Olsen BR, Berendsen AD, VEGF stimulates intramembranous bone formation during craniofacial skeletal development. Matrix Biol. 2016 May-Jul;52-54:127-40 |
1 | J:200722 Hick AC, Delmarcelle AS, Bouquet M, Klotz S, Copetti T, Forez C, Van Der Smissen P, Sonveaux P, Collet JF, Feron O, Courtoy PJ, Pierreux CE, Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiation. Dev Biol. 2013 Sep 1;381(1):227-40 |
1 | J:122952 Hung IH, Yu K, Lavine KJ, Ornitz DM, FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. Dev Biol. 2007 Jul 15;307(2):300-13 |
1 | J:321004 Jiang M, Fang Y, Li Y, Huang H, Wei Z, Gao X, Sung HK, Hu J, Qiang L, Ruan J, Chen Q, Jiang D, Whitsett JA, Ai X, Que J, VEGF receptor 2 (KDR) protects airways from mucus metaplasia through a Sox9-dependent pathway. Dev Cell. 2021 Jun 7;56(11):1646-1660.e5 |
1 | J:199291 Jiang M, Ku WY, Fu J, Offermanns S, Hsu W, Que J, Gpr177 regulates pulmonary vasculature development. Development. 2013 Sep;140(17):3589-94 |
1* | J:41032 Kabrun N, Buhring HJ, Choi K, Ullrich A, Risau W, Keller G, Flk-1 expression defines a population of early embryonic hematopoietic precursors. Development. 1997 May;124(10):2039-48 |
1 | J:119882 Liu Z, Lavine KJ, Hung IH, Ornitz DM, FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate. Dev Biol. 2007 Feb 1;302(1):80-91 |
1* | J:231234 Luna RL, Kay VR, Ratsep MT, Khalaj K, Bidarimath M, Peterson N, Carmeliet P, Jin A, Croy BA, Placental growth factor deficiency is associated with impaired cerebral vascular development in mice. Mol Hum Reprod. 2016 Feb;22(2):130-42 |
1* | J:36300 Millauer B, Wizigmann-Voos S, Schnurch H, Martinez R, Moller NP, Risau W, Ullrich A, High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis. Cell. 1993 Mar 26;72(6):835-46 |
1 | J:156690 Morimoto M, Liu Z, Cheng HT, Winters N, Bader D, Kopan R, Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate. J Cell Sci. 2010 Jan 15;123(Pt 2):213-24 |
1 | J:191589 Nishimura R, Wakabayashi M, Hata K, Matsubara T, Honma S, Wakisaka S, Kiyonari H, Shioi G, Yamaguchi A, Tsumaki N, Akiyama H, Yoneda T, Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification. J Biol Chem. 2012 Sep 28;287(40):33179-90 |
1 | J:208409 Reinert RB, Cai Q, Hong JY, Plank JL, Aamodt K, Prasad N, Aramandla R, Dai C, Levy SE, Pozzi A, Labosky PA, Wright CV, Brissova M, Powers AC, Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding. Development. 2014 Apr;141(7):1480-91 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
1 | J:181330 Sabine A, Agalarov Y, Maby-El Hajjami H, Jaquet M, Hagerling R, Pollmann C, Bebber D, Pfenniger A, Miura N, Dormond O, Calmes JM, Adams RH, Makinen T, Kiefer F, Kwak BR, Petrova TV, Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation. Dev Cell. 2012 Feb 14;22(2):430-45 |
1* | J:159519 Saharinen P, Helotera H, Miettinen J, Norrmen C, D'Amico G, Jeltsch M, Langenberg T, Vandevelde W, Ny A, Dewerchin M, Carmeliet P, Alitalo K, Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development. Genes Dev. 2010 May;24(9):875-80 |
1 | J:314585 Shadad O, Chaulagain R, Luukko K, Kettunen P, Establishment of tooth blood supply and innervation is developmentally regulated and takes place through differential patterning processes. J Anat. 2019 Apr;234(4):465-479 |
1 | J:84301 Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M, The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 2003 Jul 1;17(13):1677-89 |
1* | J:86844 Takahashi T, Takahashi K, Gerety S, Wang H, Anderson DJ, Daniel TO, Temporally compartmentalized expression of ephrin-B2 during renal glomerular development. J Am Soc Nephrol. 2001 Dec;12(12):2673-82 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:150308 Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009 May 1;182(9):5439-45 |
1 | J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34 |
2 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1* | J:75934 Zelzer E, McLean W, Ng YS, Fukai N, Reginato AM, Lovejoy S, D'Amore PA, Olsen BR, Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development. 2002 Apr;129(8):1893-904 |
1* | J:99650 Zhao L, Wang K, Ferrara N, Vu TH, Vascular endothelial growth factor co-ordinates proper development of lung epithelium and vasculature. Mech Dev. 2005 Jul-Aug;122(7-8):877-86 |
Kdsr 3-ketodihydrosphingosine reductase (Synonyms: 6330410P18Rik, 9430079B08Rik, Fvt1) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Kera keratocan (Synonyms: CNA2, SLRR2B) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
2 | J:49650 Liu CY, Shiraishi A, Kao CW, Converse RL, Funderburgh JL, Corpuz LM, Conrad GW, Kao WW, The cloning of mouse keratocan cDNA and genomic DNA and the characterization of its expression during eye development. J Biol Chem. 1998 Aug 28;273(35):22584-8 |
1* | J:73681 Saika S, Saika S, Liu CY, Azhar M, Sanford LP, Doetschman T, Gendron RL, Kao CW, Kao WW, TGFbeta2 in corneal morphogenesis during mouse embryonic development. Dev Biol. 2001 Dec 15;240(2):419-32 |
1 | J:242341 Zhang J, Upadhya D, Lu L, Reneker LW, Fibroblast growth factor receptor 2 (FGFR2) is required for corneal epithelial cell proliferation and differentiation during embryonic development. PLoS One. 2015;10(1):e0117089 |
1 | J:125580 Zhang L, Deng M, Kao CW, Kao WW, Xia Y, MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis. Mol Vis. 2003 Nov 3;9:584-93 |
KF876689 expressed sequence KF876689 | |
Results | Reference |
1* | J:212084 Herriges MJ, Swarr DT, Morley MP, Rathi KS, Peng T, Stewart KM, Morrisey EE, Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development. Genes Dev. 2014 Jun 15;28(12):1363-79 |
Khdc1a KH domain containing 1A (Synonyms: Ndg1) | |
Results | Reference |
1* | J:182840 Cai C, Tamai K, Molyneaux K, KHDC1B is a novel CPEB binding partner specifically expressed in mouse oocytes and early embryos. Mol Biol Cell. 2010 Sep 15;21(18):3137-48 |
Khdc1b KH domain containing 1B (Synonyms: Khdc1) | |
Results | Reference |
1* | J:182840 Cai C, Tamai K, Molyneaux K, KHDC1B is a novel CPEB binding partner specifically expressed in mouse oocytes and early embryos. Mol Biol Cell. 2010 Sep 15;21(18):3137-48 |
Khdc3 KH domain containing 3, subcortical maternal complex member (Synonyms: 2410004A20Rik, ecat1, FILIA) | |
Results | Reference |
1 | J:326570 Niu W, Spradling AC, Mouse oocytes develop in cysts with the help of nurse cells. Cell. 2022 Jul 7;185(14):2576-2590.e12 |
Khdrbs1 KH domain containing, RNA binding, signal transduction associated 1 (Synonyms: p62, Sam68) | |
Results | Reference |
1 | J:115775 Richard S, Torabi N, Franco GV, Tremblay GA, Chen T, Vogel G, Morel M, Cleroux P, Forget-Richard A, Komarova S, Tremblay ML, Li W, Li A, Gao YJ, Henderson JE, Ablation of the Sam68 RNA binding protein protects mice from age-related bone loss. PLoS Genet. 2005 Dec;1(6):e74 |
Kif1b kinesin family member 1B (Synonyms: A530096N05Rik, D4Mil1e, Kif1b alpha, Kif1b beta, KIF1Bp130, KIF1Bp204, mKIAA0591, N-3 kinesin) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1 | J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12) |
Kif2a kinesin family member 2A (Synonyms: Kif2, Kns2, M-kinesin) | |
Results | Reference |
1 | J:286645 Gilet JG, Ivanova EL, Trofimova D, Rudolf G, Meziane H, Broix L, Drouot N, Courraud J, Skory V, Voulleminot P, Osipenko M, Bahi-Buisson N, Yalcin B, Birling MC, Hinckelmann MV, Kwok BH, Allingham JS, Chelly J, Conditional switching of KIF2A mutation provides new insights into cortical malformation pathogeny. Hum Mol Genet. 2020 Mar 27;29(5):766-784 |
Kif3a kinesin family member 3A (Synonyms: Kif3, Kifl, kinesin-II subunit, Kns3, N-4 kinesin) | |
Results | Reference |
1 | J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6 |
Kif5a kinesin family member 5A (Synonyms: D10Bwg0738e, Khc, Kif5, Kns) | |
Results | Reference |
1 | J:229250 Cui J, Li X, Duan Z, Xue W, Wang Z, Lu S, Lin R, Liu M, Zhu G, Huang JD, Analysis of Kif5b expression during mouse kidney development. PLoS One. 2015;10(4):e0126002 |
Kif5b kinesin family member 5B (Synonyms: Khc, kinesin heavy chain) | |
Results | Reference |
2 | J:229250 Cui J, Li X, Duan Z, Xue W, Wang Z, Lu S, Lin R, Liu M, Zhu G, Huang JD, Analysis of Kif5b expression during mouse kidney development. PLoS One. 2015;10(4):e0126002 |
1 | J:358347 Dias AP, Rehmani T, Salih M, Tuana B, Tail-anchored membrane protein SLMAP3 is essential for targeting centrosomal proteins to the nuclear envelope in skeletal myogenesis. Open Biol. 2024 Oct;14(10):240094 |
1 | J:194072 Wang Z, Cui J, Wong WM, Li X, Xue W, Lin R, Wang J, Wang P, Tanner JA, Cheah KS, Wu W, Huang JD, Kif5b controls the localization of myofibril components for their assembly and linkage to the myotendinous junctions. Development. 2013 Feb 1;140(3):617-26 |
Kif5c kinesin family member 5C (Synonyms: Khc, mKIAA0531) | |
Results | Reference |
1 | J:229250 Cui J, Li X, Duan Z, Xue W, Wang Z, Lu S, Lin R, Liu M, Zhu G, Huang JD, Analysis of Kif5b expression during mouse kidney development. PLoS One. 2015;10(4):e0126002 |
Kif7 kinesin family member 7 | |
Results | Reference |
3 | J:175769 Hsu SH, Zhang X, Yu C, Li ZJ, Wunder JS, Hui CC, Alman BA, Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu. Development. 2011 Sep;138(17):3791-801 |
Kif11 kinesin family member 11 (Synonyms: Eg5, Kifl1, Knsl1) | |
Results | Reference |
1 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
Kif13a kinesin family member 13A (Synonyms: 4930505I07Rik, N-3 kinesin) | |
Results | Reference |
1 | J:306543 Yu Z, Zeng J, Wang J, Cui Y, Song X, Zhang Y, Cheng X, Hou N, Teng Y, Lan Y, Chen Y, Yang X, Hepatocyte growth factor-regulated tyrosine kinase substrate is essential for endothelial cell polarity and cerebrovascular stability. Cardiovasc Res. 2021 Jan 21;117(2):533-546 |
Kif14 kinesin family member 14 (Synonyms: D1Ertd367e, N-3 kinesin) | |
Results | Reference |
1 | J:195809 Fujikura K, Setsu T, Tanigaki K, Abe T, Kiyonari H, Terashima T, Sakisaka T, Kif14 mutation causes severe brain malformation and hypomyelination. PLoS One. 2013;8(1):e53490 |
Kif18b kinesin family member 18B (Synonyms: 3000004C01Rik, N-8 kinesin) | |
Results | Reference |
1* | J:324129 Moreci RS, Lechler T, KIF18B is a cell type-specific regulator of spindle orientation in the epidermis. Mol Biol Cell. 2021 Nov 1;32(21):ar29 |
Kif20b kinesin family member 20B (Synonyms: 33cex, C330014J10Rik, Kif20b, magoo, Mphosph1, N-6 kinesin) | |
Results | Reference |
1 | J:205043 Janisch KM, Vock VM, Fleming MS, Shrestha A, Grimsley-Myers CM, Rasoul BA, Neale SA, Cupp TD, Kinchen JM, Liem KF Jr, Dwyer ND, The vertebrate-specific Kinesin-6, Kif20b, is required for normal cytokinesis of polarized cortical stem cells and cerebral cortex size. Development. 2013 Dec;140(23):4672-82 |
Kif21a kinesin family member 21A (Synonyms: mKIAA1708, N-5 kinesin) | |
Results | Reference |
1* | J:186073 Yamada K, Andrews C, Chan WM, McKeown CA, Magli A, de Berardinis T, Loewenstein A, Lazar M, O'Keefe M, Letson R, London A, Ruttum M, Matsumoto N, Saito N, Morris L, Del Monte M, Johnson RH, Uyama E, Houtman WA, de Vries B, Carlow TJ, Hart BL, Krawiecki N, Shoffner J, Vogel MC, Katowitz J, Goldstein SM, Levin AV, Sener EC, Ozturk BT, Akarsu AN, Brodsky MC, Hanisch F, Cruse RP, Zubcov AA, Robb RM, Roggenkaemper P, Gottlob I, Kowal L, Battu R, Traboulsi EI, Franceschini P, Newlin A, Demer JL, Engle EC, Heterozygous mutations of the kinesin KIF21A in congenital fibrosis of the extraocular muscles type 1 (CFEOM1). Nat Genet. 2003 Dec;35(4):318-21 |
Kif21b kinesin family member 21B (Synonyms: 2610511N21Rik, mKIAA0449, N-5 kinesin) | |
Results | Reference |
4* | J:292175 Asselin L, Rivera Alvarez J, Heide S, Bonnet CS, Tilly P, Vitet H, Weber C, Bacino CA, Baranano K, Chassevent A, Dameron A, Faivre L, Hanchard NA, Mahida S, McWalter K, Mignot C, Nava C, Rastetter A, Streff H, Thauvin-Robinet C, Weiss MM, Zapata G, Zwijnenburg PJG, Saudou F, Depienne C, Golzio C, Heron D, Godin JD, Mutations in the KIF21B kinesin gene cause neurodevelopmental disorders through imbalanced canonical motor activity. Nat Commun. 2020 May 15;11(1):2441 |
Kif23 kinesin family member 23 (Synonyms: 3110001D19Rik, C87313, CHO1, Knsl5, MKLP-1, MKLP1) | |
Results | Reference |
1 | J:361026 Naher S, Iemura K, Miyashita S, Hoshino M, Tanaka K, Niwa S, Tsai JW, Kikkawa T, Osumi N, Kinesin-like motor protein KIF23 maintains neural stem and progenitor cell pools in the developing cortex. EMBO J. 2025 Jan;44(2):331-355 |
Kif26a kinesin family member 26A (Synonyms: mKIAA1236, N-11 kinesin) | |
Results | Reference |
1 | J:330578 Qian X, DeGennaro EM, Talukdar M, Akula SK, Lai A, Shao DD, Gonzalez D, Marciano JH, Smith RS, Hylton NK, Yang E, Bazan JF, Barrett L, Yeh RC, Hill RS, Beck SG, Otani A, Angad J, Mitani T, Posey JE, Pehlivan D, Calame D, Aydin H, Yesilbas O, Parks KC, Argilli E, England E, Im K, Taranath A, Scott HS, Barnett CP, Arts P, Sherr EH, Lupski JR, Walsh CA, Loss of non-motor kinesin KIF26A causes congenital brain malformations via dysregulated neuronal migration and axonal growth as well as apoptosis. Dev Cell. 2022 Oct 24;57(20):2381-2396.e13 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Kifap3 kinesin-associated protein 3 (Synonyms: KAP3) | |
Results | Reference |
1* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
Kifc2 kinesin family member C2 | |
Results | Reference |
1 | J:39083 Hanlon DW, Yang Z, Goldstein LS, Characterization of KIFC2, a neuronal kinesin superfamily member in mouse. Neuron. 1997 Mar;18(3):439-51 |
Kirrel1 kirre like nephrin family adhesion molecule 1 (Synonyms: 6720469N11Rik, Kirrel, Kirrel1, Neph1) | |
Results | Reference |
3* | J:352627 Baltar J, Miranda RM, Cabral M, Rebelo S, Grahammer F, Huber TB, Reguenga C, Monteiro FA, Neph1 is required for neurite branching and is negatively regulated by the PRRXL1 homeodomain factor in the developing spinal cord dorsal horn. Neural Dev. 2024 Jul 24;19(1):13 |
1* | J:147029 Gerke P, Benzing T, Hohne M, Kispert A, Frotscher M, Walz G, Kretz O, Neuronal expression and interaction with the synaptic protein CASK suggest a role for Neph1 and Neph2 in synaptogenesis. J Comp Neurol. 2006 Oct 1;498(4):466-75 |
1 | J:140256 Hartleben B, Schweizer H, Lubben P, Bartram MP, Moller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB, Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. J Biol Chem. 2008 Aug 22;283(34):23033-8 |
1 | J:171288 Nishida K, Nakayama K, Yoshimura S, Murakami F, Role of Neph2 in pontine nuclei formation in the developing hindbrain. Mol Cell Neurosci. 2011 Mar;46(3):662-70 |
1* | J:316176 Volker LA, Petry M, Abdelsabour-Khalaf M, Schweizer H, Yusuf F, Busch T, Schermer B, Benzing T, Brand-Saberi B, Kretz O, Hohne M, Kispert A, Comparative analysis of Neph gene expression in mouse and chicken development. Histochem Cell Biol. 2012 Mar;137(3):355-66 |
Kirrel2 kirre like nephrin family adhesion molecule 2 (Synonyms: C330019F22Rik, NEPH3) | |
Results | Reference |
1 | J:171288 Nishida K, Nakayama K, Yoshimura S, Murakami F, Role of Neph2 in pontine nuclei formation in the developing hindbrain. Mol Cell Neurosci. 2011 Mar;46(3):662-70 |
1* | J:316176 Volker LA, Petry M, Abdelsabour-Khalaf M, Schweizer H, Yusuf F, Busch T, Schermer B, Benzing T, Brand-Saberi B, Kretz O, Hohne M, Kispert A, Comparative analysis of Neph gene expression in mouse and chicken development. Histochem Cell Biol. 2012 Mar;137(3):355-66 |
Kirrel3 kirre like nephrin family adhesion molecule 3 (Synonyms: 1500010O20Rik, 2900036G11Rik, mKIAA1867, Neph2) | |
Results | Reference |
1* | J:147029 Gerke P, Benzing T, Hohne M, Kispert A, Frotscher M, Walz G, Kretz O, Neuronal expression and interaction with the synaptic protein CASK suggest a role for Neph1 and Neph2 in synaptogenesis. J Comp Neurol. 2006 Oct 1;498(4):466-75 |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
2 | J:171288 Nishida K, Nakayama K, Yoshimura S, Murakami F, Role of Neph2 in pontine nuclei formation in the developing hindbrain. Mol Cell Neurosci. 2011 Mar;46(3):662-70 |
1* | J:316176 Volker LA, Petry M, Abdelsabour-Khalaf M, Schweizer H, Yusuf F, Busch T, Schermer B, Benzing T, Brand-Saberi B, Kretz O, Hohne M, Kispert A, Comparative analysis of Neph gene expression in mouse and chicken development. Histochem Cell Biol. 2012 Mar;137(3):355-66 |
Kiss1 KiSS-1 metastasis-suppressor (Synonyms: kisspeptin, metastin) | |
Results | Reference |
1 | J:207602 Kumar D, Freese M, Drexler D, Hermans-Borgmeyer I, Marquardt A, Boehm U, Murine arcuate nucleus kisspeptin neurons communicate with GnRH neurons in utero. J Neurosci. 2014 Mar 5;34(10):3756-66 |
1 | J:226927 Kumar D, Periasamy V, Freese M, Voigt A, Boehm U, In Utero Development of Kisspeptin/GnRH Neural Circuitry in Male Mice. Endocrinology. 2015 Sep;156(9):3084-90 |
1* | J:333014 Wartenberg P, Farkas I, Csillag V, Colledge WH, Hrabovszky E, Boehm U, Sexually Dimorphic Neurosteroid Synthesis Regulates Neuronal Activity in the Murine Brain. J Neurosci. 2021 Nov 3;41(44):9177-9191 |
Kit KIT proto-oncogene receptor tyrosine kinase (Synonyms: belly-spot, CD117, c-KIT, Dominant white spotting, Gsfsco1, Gsfsco5, Gsfsow3, SCO1, SCO5, SOW3, Steel Factor Receptor, Tr-kit) | |
Results | Reference |
1 | J:36230 Bernex F, De Sepulveda P, Kress C, Elbaz C, Delouis C, Panthier JJ, Spatial and temporal patterns of c-kit-expressing cells in WlacZ/+ and WlacZ/WlacZ mouse embryos. Development. 1996 Oct;122(10):3023-33 |
1 | J:197180 Buniello A, Hardisty-Hughes RE, Pass JC, Bober E, Smith RJ, Steel KP, Headbobber: a combined morphogenetic and cochleosaccular mouse model to study 10qter deletions in human deafness. PLoS One. 2013;8(2):e56274 |
2 | J:81852 Doneda L, Klinger FG, Larizza L, De Felici M, KL/KIT co-expression in mouse fetal oocytes. Int J Dev Biol. 2002 Dec;46(8):1015-21 |
1 | J:362521 Guo XL, Wang YD, Liu YJ, Chu L, Zhu H, Hu Y, Wu RY, Xie HY, Yu J, Li SP, Xiong CY, Li RY, Ke F, Chen L, Chen GQ, Chen L, Bai F, Enver T, Li GH, Li HF, Hong DL, Fetal hepatocytes protect the HSPC genome via fetuin-A. Nature. 2025 Jan;637(8045):402-411 |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
1* | J:202252 Jones RL, Pepling ME, KIT signaling regulates primordial follicle formation in the neonatal mouse ovary. Dev Biol. 2013 Oct 1;382(1):186-97 |
1 | J:103257 Lacosta AM, Muniesa P, Ruberte J, Sarasa M, Dominguez L, Novel expression patterns of Pax3/Pax7 in early trunk neural crest and its melanocyte and non-melanocyte lineages in amniote embryos. Pigment Cell Res. 2005 Aug;18(4):243-51 |
1 | J:322701 Liu Y, Chen Q, Jeong HW, Koh BI, Watson EC, Xu C, Stehling M, Zhou B, Adams RH, A specialized bone marrow microenvironment for fetal haematopoiesis. Nat Commun. 2022 Mar 14;13(1):1327 |
1* | J:33511 Manova K, Bachvarova RF, Expression of c-kit encoded at the W locus of mice in developing embryonic germ cells and presumptive melanoblasts. Dev Biol. 1991 Aug;146(2):312-24 |
1* | J:1854 Motro B, van der Kooy D, Rossant J, Reith A, Bernstein A, Contiguous patterns of c-kit and steel expression: analysis of mutations at the W and Sl loci. Development. 1991 Dec;113(4):1207-21 |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
1 | J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34 |
1* | J:241573 Pui HP, Saga Y, Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling. Mech Dev. 2017 Apr;144(Pt B):125-139 |
1* | J:176776 Roberts RR, Ellis M, Gwynne RM, Bergner AJ, Lewis MD, Beckett EA, Bornstein JC, Young HM, The first intestinal motility patterns in fetal mice are not mediated by neurons or interstitial cells of Cajal. J Physiol. 2010 Apr 1;588(Pt 7):1153-69 |
1* | J:209131 Saba R, Wu Q, Saga Y, CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways. Dev Biol. 2014 May 15;389(2):173-81 |
1 | J:227907 Sultana N, Zhang L, Yan J, Chen J, Cai W, Razzaque S, Jeong D, Sheng W, Bu L, Xu M, Huang GY, Hajjar RJ, Zhou B, Moon A, Cai CL, Resident c-kit(+) cells in the heart are not cardiac stem cells. Nat Commun. 2015;6:8701 |
1 | J:282279 Ustun Y, Reibetanz M, Brachvogel B, Nischt R, Eckes B, Zigrino P, Krieg T, Dual role of laminin511 in regulating melanocyte migration and differentiation. Matrix Biol. 2019 Jul;80:59-71 |
1* | J:210584 van Berlo JH, Kanisicak O, Maillet M, Vagnozzi RJ, Karch J, Lin SC, Middleton RC, Marban E, Molkentin JD, c-kit+ cells minimally contribute cardiomyocytes to the heart. Nature. 2014 May 15;509(7500):337-41 |
2 | J:91146 Yamatani H, Sato Y, Fujisawa H, Hirata T, Chronotopic organization of olfactory bulb axons in the lateral olfactory tract. J Comp Neurol. 2004 Jul 19;475(2):247-60 |
Kitl kit ligand (Synonyms: blz, Gb, grizzle-belly, Kitlg, Mgf, SCF, SF, Sl, SLF, Steel, Steel factor, stem cell factor) | |
Results | Reference |
1* | J:159378 Chou S, Lodish HF, Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7799-804 |
3 | J:81852 Doneda L, Klinger FG, Larizza L, De Felici M, KL/KIT co-expression in mouse fetal oocytes. Int J Dev Biol. 2002 Dec;46(8):1015-21 |
1 | J:308976 He DD, Tang XT, Dong W, Cui G, Peng G, Yin X, Chen Y, Jing N, Zhou BO, C-KIT Expression Distinguishes Fetal from Postnatal Skeletal Progenitors. Stem Cell Reports. 2020 Apr 14;14(4):614-630 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:202252 Jones RL, Pepling ME, KIT signaling regulates primordial follicle formation in the neonatal mouse ovary. Dev Biol. 2013 Oct 1;382(1):186-97 |
1* | J:1854 Motro B, van der Kooy D, Rossant J, Reith A, Bernstein A, Contiguous patterns of c-kit and steel expression: analysis of mutations at the W and Sl loci. Development. 1991 Dec;113(4):1207-21 |
1* | J:49918 Murray AM, Simm B, Beagley KW, Cytokine gene expression in murine fetal intestine: potential for extrathymic T cell development. Cytokine. 1998 May;10(5):337-45 |
1 | J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34 |
2 | J:222261 Tan KS, Inoue T, Kulkeaw K, Tanaka Y, Lai MI, Sugiyama D, Localized SCF and IGF-1 secretion enhances erythropoiesis in the spleen of murine embryos. Biol Open. 2015;4(5):596-607 |
1* | J:287411 Tran HN, Park W, Seong S, Jeong JE, Nguyen QH, Yoon J, Baek K, Jeong Y, Tcf7l2 transcription factor is required for the maintenance, but not the initial specification, of the neurotransmitter identity in the caudal thalamus. Dev Dyn. 2020 May;249(5):646-655 |
Kiz kizuna centrosomal protein (Synonyms: Gm114, LOC228730, Ncrna00153, Plk1s1) | |
Results | Reference |
2* | J:136802 Tang H, Ross A, Capel B, Expression and functional analysis of Gm114, a putative mammalian ortholog of Drosophila bam. Dev Biol. 2008 Jun 1;318(1):73-81 |
Klf1 Kruppel-like transcription factor 1 (erythroid) (Synonyms: Eklf, Nan) | |
Results | Reference |
1* | J:271614 Gudmundsdottir B, Gudmundsson KO, Klarmann KD, Singh SK, Sun L, Singh S, Du Y, Coppola V, Stockwin L, Nguyen N, Tessarollo L, Thorsteinsson L, Sigurjonsson OE, Gudmundsson S, Rafnar T, Tisdale JF, Keller JR, POGZ Is Required for Silencing Mouse Embryonic beta-like Hemoglobin and Human Fetal Hemoglobin Expression. Cell Rep. 2018 Jun 12;23(11):3236-3248 |
1* | J:285404 Ueda T, Yokota T, Okuzaki D, Uno Y, Mashimo T, Kubota Y, Sudo T, Ishibashi T, Shingai Y, Doi Y, Ozawa T, Nakai R, Tanimura A, Ichii M, Ezoe S, Shibayama H, Oritani K, Kanakura Y, Endothelial Cell-Selective Adhesion Molecule Contributes to the Development of Definitive Hematopoiesis in the Fetal Liver. Stem Cell Reports. 2019 Dec 10;13(6):992-1005 |
Klf2 Kruppel-like transcription factor 2 (lung) (Synonyms: Lklf) | |
Results | Reference |
1* | J:271614 Gudmundsdottir B, Gudmundsson KO, Klarmann KD, Singh SK, Sun L, Singh S, Du Y, Coppola V, Stockwin L, Nguyen N, Tessarollo L, Thorsteinsson L, Sigurjonsson OE, Gudmundsson S, Rafnar T, Tisdale JF, Keller JR, POGZ Is Required for Silencing Mouse Embryonic beta-like Hemoglobin and Human Fetal Hemoglobin Expression. Cell Rep. 2018 Jun 12;23(11):3236-3248 |
1 | J:199291 Jiang M, Ku WY, Fu J, Offermanns S, Hsu W, Que J, Gpr177 regulates pulmonary vasculature development. Development. 2013 Sep;140(17):3589-94 |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
Klf3 Kruppel-like transcription factor 3 (basic) (Synonyms: 9930027G08Rik, Bklf, BKLF, Tef-2) | |
Results | Reference |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Klf4 Kruppel-like transcription factor 4 (gut) (Synonyms: EZF, Gklf, Zie) | |
Results | Reference |
2 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1* | J:84665 Ehlermann J, Pfisterer P, Schorle H, Dynamic expression of Kruppel-like factor 4 (Klf4), a target of transcription factor AP-2alpha during murine mid-embryogenesis. Anat Rec A Discov Mol Cell Evol Biol. 2003 Aug;273(2):677-80 |
1* | J:257227 Fujikawa J, Takeuchi Y, Kanazawa S, Nomir AG, Kito A, Elkhashab E, Ghaleb AM, Yang VW, Akiyama S, Morisaki I, Yamashiro T, Wakisaka S, Abe M, Kruppel-like factor 4 regulates matrix metalloproteinase and aggrecanase gene expression in chondrocytes. Cell Tissue Res. 2017 Dec;370(3):441-449 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
2 | J:83259 Jaubert J, Cheng J, Segre JA, Ectopic expression of kruppel like factor 4 (Klf4) accelerates formation of the epidermal permeability barrier. Development. 2003 Jun;130(12):2767-77 |
1 | J:326547 Lu P, Wang P, Wu B, Wang Y, Liu Y, Cheng W, Feng X, Yuan X, Atteya MM, Ferro H, Sugi Y, Rydquist G, Esmaily M, Butcher JT, Chang CP, Lenz J, Zheng D, Zhou B, A SOX17-PDGFB signaling axis regulates aortic root development. Nat Commun. 2022 Jul 13;13(1):4065 |
1 | J:153617 O'Shaughnessy RF, Welti JC, Sully K, Byrne C, Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development. Development. 2009 Oct;136(20):3423-31 |
1* | J:61393 Ohnishi S, Laub F, Matsumoto N, Asaka M, Ramirez F, Yoshida T, Terada M, Developmental expression of the mouse gene coding for the kruppel-like transcription factor KLF5. Dev Dyn. 2000 Apr;217(4):421-9 |
1* | J:54202 Panigada M, Porcellini S, Sutti F, Doneda L, Pozzoli O, Consalez GG, Guttinger M, Grassi F, GKLF in thymus epithelium as a developmentally regulated element of thymocyte-stroma cross-talk. Mech Dev. 1999 Mar;81(1-2):103-13 |
1 | J:180141 Qin S, Liu M, Niu W, Zhang CL, Dysregulation of Kruppel-like factor 4 during brain development leads to hydrocephalus in mice. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21117-21 |
1* | J:56495 Segre JA, Bauer C, Fuchs E, Klf4 is a transcription factor required for establishing the barrier function of the skin. Nat Genet. 1999 Aug;22(4):356-60 |
2 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
1 | J:269997 Takeuchi Y, Kito A, Itoh S, Naruse H, Fujikawa J, Sadek KM, Akiyama S, Yamashiro T, Wakisaka S, Abe M, Kruppel-Like Factor 4 represses osteoblast differentiation via ciliary Hedgehog signaling. Exp Cell Res. 2018 Oct 15;371(2):417-425 |
1 | J:346785 Wang S, Zhang H, Wiltshire T, Sealock R, Faber JE, Genetic dissection of the Canq1 locus governing variation in extent of the collateral circulation. PLoS One. 2012;7(3):e31910 |
Klf5 Kruppel-like transcription factor 5 (Synonyms: 4930520J07Rik, Bteb2, CKLF, IKLF) | |
Results | Reference |
1 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1 | J:176604 Bell SM, Zhang L, Mendell A, Xu Y, Haitchi HM, Lessard JL, Whitsett JA, Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. Dev Biol. 2011 Oct 1;358(1):79-90 |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
2* | J:175263 Kenchegowda D, Swamynathan S, Gupta D, Wan H, Whitsett J, Swamynathan SK, Conditional disruption of mouse Klf5 results in defective eyelids with malformed meibomian glands, abnormal cornea and loss of conjunctival goblet cells. Dev Biol. 2011 Aug 1;356(1):5-18 |
1* | J:70833 Laub F, Aldabe R, Ramirez F, Friedman S, Embryonic expression of Kruppel-like factor 6 in neural and non-neural tissues. Mech Dev. 2001 Aug;106(1-2):167-70 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1* | J:61393 Ohnishi S, Laub F, Matsumoto N, Asaka M, Ramirez F, Yoshida T, Terada M, Developmental expression of the mouse gene coding for the kruppel-like transcription factor KLF5. Dev Dyn. 2000 Apr;217(4):421-9 |
1 | J:141868 Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H, Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9. J Biol Chem. 2008 Sep 5;283(36):24682-9 |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Klf6 Kruppel-like transcription factor 6 (Synonyms: BCD1, Copeb, CPBP, FM2, FM6, Ierepo1, Ierepo3, Zf9) | |
Results | Reference |
1 | J:235955 Laitman BM, Asp L, Mariani JN, Zhang J, Liu J, Sawai S, Chapouly C, Horng S, Kramer EG, Mitiku N, Loo H, Burlant N, Pedre X, Hara Y, Nudelman G, Zaslavsky E, Lee YM, Braun DA, Lu QR, Narla G, Raine CS, Friedman SL, Casaccia P, John GR, The Transcriptional Activator Kruppel-like Factor-6 Is Required for CNS Myelination. PLoS Biol. 2016 May;14(5):e1002467 |
1* | J:70833 Laub F, Aldabe R, Ramirez F, Friedman S, Embryonic expression of Kruppel-like factor 6 in neural and non-neural tissues. Mech Dev. 2001 Aug;106(1-2):167-70 |
Klf7 Kruppel-like transcription factor 7 (ubiquitous) (Synonyms: 9830124P08Rik) | |
Results | Reference |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1 | J:69467 Laub F, Aldabe R, Friedrich V Jr, Ohnishi S, Yoshida T, Ramirez F, Developmental expression of mouse Kruppel-like transcription factor KLF7 suggests a potential role in neurogenesis. Dev Biol. 2001 May 15;233(2):305-18 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
Klf10 Kruppel-like transcription factor 10 (Synonyms: Egral, Gdnfif, mGIF, Tieg1) | |
Results | Reference |
1* | J:316653 Chen Z, Li W, Wang H, Wan C, Luo D, Deng S, Chen H, Chen S, Klf10 regulates odontoblast differentiation and mineralization via promoting expression of dentin matrix protein 1 and dentin sialophosphoprotein genes. Cell Tissue Res. 2016 Feb;363(2):385-98 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
Klf15 Kruppel-like transcription factor 15 (Synonyms: 1810013I09Rik, CKLF, hlb444, KKLF) | |
Results | Reference |
1* | J:99372 van der Zwaag B, Burbach JP, Scharfe C, Oefner PJ, Brunner HG, Padberg GW, van Bokhoven H, Identifying new candidate genes for hereditary facial paresis on chromosome 3q21-q22 by RNA in situ hybridization in mouse. Genomics. 2005 Jul;86(1):55-67 |
Klk1 kallikrein 1 (Synonyms: 0610007D04Rik, Klk6, mGk-6) | |
Results | Reference |
1 | J:2808 Penschow JD, Coghlan JP, Sites of glandular kallikrein gene expression in fetal mice. Mol Cell Endocrinol. 1992 Oct;88(1-3):23-30 |
Klk1b3 kallikrein 1-related peptidase b3 (Synonyms: mGk-3, Ngfg) | |
Results | Reference |
1 | J:65040 Botchkareva NV, Botchkarev VA, Albers KM, Metz M, Paus R, Distinct roles for nerve growth factor and brain-derived neurotrophic factor in controlling the rate of hair follicle morphogenesis. J Invest Dermatol. 2000 Feb;114(2):314-20 |
Klk1b4 kallikrein 1-related pepidase b4 (Synonyms: mGk-4, Ngfa) | |
Results | Reference |
1 | J:65040 Botchkareva NV, Botchkarev VA, Albers KM, Metz M, Paus R, Distinct roles for nerve growth factor and brain-derived neurotrophic factor in controlling the rate of hair follicle morphogenesis. J Invest Dermatol. 2000 Feb;114(2):314-20 |
Klk7 kallikrein related-peptidase 7 (chymotryptic, stratum corneum) (Synonyms: Prss6) | |
Results | Reference |
1 | J:163484 Lin MH, Chang KW, Lin SC, Miner JH, Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling. Dev Biol. 2010 Aug 15;344(2):707-19 |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Klk8 kallikrein related-peptidase 8 (Synonyms: BSP1, Nrpn, Prss19) | |
Results | Reference |
2* | J:46162 Chen ZL, Momota Y, Kato K, Taniguchi M, Inoue N, Shiosaka S, Yoshida S, Expression of neuropsin mRNA in the mouse embryo and the pregnant uterus. J Histochem Cytochem. 1998 Mar;46(3):313-20 |
Klk10 kallikrein related-peptidase 10 (Synonyms: 2300002A13Rik, NES1, PRSSL1) | |
Results | Reference |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
Klrc1 killer cell lectin-like receptor subfamily C, member 1 (Synonyms: CD159a, NKG2A, NKG2B) | |
Results | Reference |
1* | J:170267 Chaignat E, Yahya-Graison EA, Henrichsen CN, Chrast J, Schutz F, Pradervand S, Reymond A, Copy number variation modifies expression time courses. Genome Res. 2011 Jan;21(1):106-13 |
Kmt2c lysine (K)-specific methyltransferase 2C (Synonyms: E330008K23Rik, HALR, mKIAA1506, Mll3) | |
Results | Reference |
1* | J:107236 Brun ME, Gasca S, Girard C, Bouton K, De Massy B, De Sario A, Characterization and expression analysis during embryo development of the mouse ortholog of MLL3. Gene. 2006 Apr 12;371(1):25-33 |
Kmt2d lysine (K)-specific methyltransferase 2D (Synonyms: C430014K11Rik, Mll2, Mll4) | |
Results | Reference |
1 | J:316097 Pang L, Tian H, Gao X, Wang W, Wang X, Zhang Z, KMT2D deficiency disturbs the proliferation and cell cycle activity of dental epithelial cell line (LS8) partially via Wnt signaling. Biosci Rep. 2021 Nov 26;41(11) |
Kpna1 karyopherin subunit alpha 1 (Synonyms: importin alpha 5, m-importin-alpha-S1, mSRP1, NPI1, Rch2) | |
Results | Reference |
1 | J:235955 Laitman BM, Asp L, Mariani JN, Zhang J, Liu J, Sawai S, Chapouly C, Horng S, Kramer EG, Mitiku N, Loo H, Burlant N, Pedre X, Hara Y, Nudelman G, Zaslavsky E, Lee YM, Braun DA, Lu QR, Narla G, Raine CS, Friedman SL, Casaccia P, John GR, The Transcriptional Activator Kruppel-like Factor-6 Is Required for CNS Myelination. PLoS Biol. 2016 May;14(5):e1002467 |
Kpna2 karyopherin subunit alpha 2 (Synonyms: 2410044B12Rik, Importin alpha, importin alpha 1, m-importin, m-importin-alpha-P1, pendulin, Rch1) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Kpna3 karyopherin subunit alpha 3 (Synonyms: importin alpha 4, IPOA4) | |
Results | Reference |
1* | J:123290 Hogarth CA, Jans DA, Loveland KL, Subcellular distribution of importins correlates with germ cell maturation. Dev Dyn. 2007 Aug;236(8):2311-20 |
Kpna4 karyopherin subunit alpha 4 (Synonyms: 1110058D08Rik, importin alpha 3, IPOA3) | |
Results | Reference |
1* | J:123290 Hogarth CA, Jans DA, Loveland KL, Subcellular distribution of importins correlates with germ cell maturation. Dev Dyn. 2007 Aug;236(8):2311-20 |
Kpnb1 karyopherin subunit beta 1 (Synonyms: Impnb) | |
Results | Reference |
2* | J:123290 Hogarth CA, Jans DA, Loveland KL, Subcellular distribution of importins correlates with germ cell maturation. Dev Dyn. 2007 Aug;236(8):2311-20 |
Kras Kirsten rat sarcoma viral oncogene homolog (Synonyms: Ki-ras, K-ras, Kras-2, Kras2) | |
Results | Reference |
1* | J:320537 Newlaczyl AU, Coulson JM, Prior IA, Quantification of spatiotemporal patterns of Ras isoform expression during development. Sci Rep. 2017 Jan 24;7:41297 |
Kremen2 kringle containing transmembrane protein 2 (Synonyms: 2900054E04Rik, Krm2) | |
Results | Reference |
1 | J:111051 Cui CY, Hashimoto T, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9142-7 |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
Krit1 KRIT1, ankyrin repeat containing (Synonyms: 2010007K12Rik, A630036P20Rik, Ccm1, Krit1, Krit1A, Krit1B) | |
Results | Reference |
1* | J:79191 Denier C, Gasc J, Chapon F, Domenga V, Lescoat C, Joutel A, Tournier-Lasserve E, Krit1/cerebral cavernous malformation 1 mRNA is preferentially expressed in neurons and epithelial cells in embryo and adult. Mech Dev. 2002 Sep;117(1-2):363 |
Krt1 keratin 1 (Synonyms: Krt-2.1, Krt2-1) | |
Results | Reference |
1 | J:233601 Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP, Harwood CA, Byrne C, O'Shaughnessy RF, Bergamaschi D, Constitutive Autophagy and Nucleophagy during Epidermal Differentiation. J Invest Dermatol. 2016 Jul;136(7):1460-70 |
1 | J:192176 Casanova JC, Travisano S, de la Pompa JL, Epithelial-to-mesenchymal transition in epicardium is independent of snail1. Genesis. 2013 Jan;51(1):32-40 |
1* | J:129949 Cui CY, Kunisada M, Esibizione D, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet. 2007 Nov 1;16(21):2583-90 |
1 | J:306061 Damen M, Wirtz L, Soroka E, Khatif H, Kukat C, Simons BD, Bazzi H, High proliferation and delamination during skin epidermal stratification. Nat Commun. 2021 May 28;12(1):3227 |
1* | J:136080 Guttormsen J, Koster MI, Stevens JR, Roop DR, Williams T, Winger QA, Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice. Dev Biol. 2008 May 1;317(1):187-95 |
1 | J:83259 Jaubert J, Cheng J, Segre JA, Ectopic expression of kruppel like factor 4 (Klf4) accelerates formation of the epidermal permeability barrier. Development. 2003 Jun;130(12):2767-77 |
1* | J:94541 Jonker L, Kist R, Aw A, Wappler I, Peters H, Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium. Mech Dev. 2004 Nov;121(11):1313-22 |
1 | J:135131 Kashiwagi M, Morgan BA, Georgopoulos K, The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny. Development. 2007 Apr;134(8):1571-82 |
1 | J:125902 Koster MI, Dai D, Marinari B, Sano Y, Costanzo A, Karin M, Roop DR, p63 induces key target genes required for epidermal morphogenesis. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3255-60 |
1 | J:261926 Kwon E, Todorova K, Wang J, Horos R, Lee KK, Neel VA, Negri GL, Sorensen PH, Lee SW, Hentze MW, Mandinova A, The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level. Nat Commun. 2018 Apr 30;9(1):1734 |
1 | J:332513 Laporte E, De Vriendt S, Hoekx J, Vankelecom H, Interleukin-6 is dispensable in pituitary normal development and homeostasis but needed for pituitary stem cell activation following local injury. Front Endocrinol (Lausanne). 2022;13:1092063 |
1 | J:213415 Lee B, Villarreal-Ponce A, Fallahi M, Ovadia J, Sun P, Yu QC, Ito S, Sinha S, Nie Q, Dai X, Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells. Dev Cell. 2014 Apr 14;29(1):47-58 |
1 | J:54224 Lee D, Prowse DM, Brissette JL, Association between mouse nude gene expression and the initiation of epithelial terminal differentiation. Dev Biol. 1999 Apr 15;208(2):362-74 |
1 | J:134270 Lee JH, Kim TS, Yang TH, Koo BK, Oh SP, Lee KP, Oh HJ, Lee SH, Kong YY, Kim JM, Lim DS, A crucial role of WW45 in developing epithelial tissues in the mouse. EMBO J. 2008 Apr 23;27(8):1231-42 |
1 | J:352165 Lin Y, Tang W, Huang P, Wang Z, Duan L, Jia C, Sun R, Liu L, Shen J, Denticleless E3 ubiquitin protein ligase (DTL) maintains the proliferation and differentiation of epidermis and hair follicles during skin development. Dev Dyn. 2024 Jul;253(7):635-647 |
2 | J:279389 Miao Q, Hill MC, Chen F, Mo Q, Ku AT, Ramos C, Sock E, Lefebvre V, Nguyen H, SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair. Nat Commun. 2019 Sep 6;10(1):4042 |
1 | J:171374 Osorio KM, Lilja KC, Tumbar T, Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol. 2011 Apr 4;193(1):235-50 |
1 | J:181138 Taylor DK, Bubier JA, Silva KA, Sundberg JP, Development, structure, and keratin expression in C57BL/6J mouse eccrine glands. Vet Pathol. 2012 Jan;49(1):146-54 |
1 | J:196491 Torchia EC, Zhang L, Huebner AJ, Sen S, Roop DR, Aurora kinase-A deficiency during skin development impairs cell division and stratification. J Invest Dermatol. 2013 Jan;133(1):78-86 |
1* | J:117802 Troy TC, Li Y, O'malley L, Turksen K, The temporal and spatial expression of Claudins in epidermal development and the accelerated program of epidermal differentiation in K14-CaSR transgenic mice. Gene Expr Patterns. 2007 Feb;7(4):423-30 |
1 | J:338452 Wang D, Li H, Chandel NS, Dou Y, Yi R, MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters. Nat Commun. 2023 Jul 21;14(1):4404 |
1 | J:141958 Yang SH, Andl T, Grachtchouk V, Wang A, Liu J, Syu LJ, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA, Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta-catenin signaling. Nat Genet. 2008 Sep 1;40(9):1130-5 |
1 | J:141138 Zhang Y, Burgess D, Overbeek PA, Govindarajan V, Dominant inhibition of lens placode formation in mice. Dev Biol. 2008 Nov 1;323(1):53-63 |
1 | J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687 |
Krt2 keratin 2 (Synonyms: Krt2-17, Krt2-2, Krt2e) | |
Results | Reference |
1* | J:94541 Jonker L, Kist R, Aw A, Wappler I, Peters H, Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium. Mech Dev. 2004 Nov;121(11):1313-22 |
Krt4 keratin 4 (Synonyms: K4, Krt-2.4, Krt2-4) | |
Results | Reference |
1 | J:233601 Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP, Harwood CA, Byrne C, O'Shaughnessy RF, Bergamaschi D, Constitutive Autophagy and Nucleophagy during Epidermal Differentiation. J Invest Dermatol. 2016 Jul;136(7):1460-70 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:227725 Kaushal GS, Rognoni E, Lichtenberger BM, Driskell RR, Kretzschmar K, Hoste E, Watt FM, Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation. J Invest Dermatol. 2015 Dec;135(12):2926-34 |
1 | J:103004 Zhang H, Hara M, Seki K, Fukuda K, Nishida T, Eyelid fusion and epithelial differentiation at the ocular surface during mouse embryonic development. Jpn J Ophthalmol. 2005 May-Jun;49(3):195-204 |
Krt5 keratin 5 (Synonyms: 3300001P10Rik, K5, Krt2-5, Tfip8) | |
Results | Reference |
1 | J:97344 Akiyama T, Maeda S, Yamane S, Ogino K, Kasai M, Kajiura F, Matsumoto M, Inoue J, Dependence of self-tolerance on TRAF6-directed development of thymic stroma. Science. 2005 Apr 8;308(5719):248-51 |
1 | J:139649 Akiyama T, Shimo Y, Yanai H, Qin J, Ohshima D, Maruyama Y, Asaumi Y, Kitazawa J, Takayanagi H, Penninger JM, Matsumoto M, Nitta T, Takahama Y, Inoue J, The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. Immunity. 2008 Sep;29(3):423-37 |
1 | J:276488 Bilodeau M, Shojaie S, Ackerley C, Post M, Rossant J, Identification of a proximal progenitor population from murine fetal lungs with clonogenic and multilineage differentiation potential. Stem Cell Reports. 2014 Oct 14;3(4):634-49 |
1 | J:262819 Bohnenpoll T, Feraric S, Nattkemper M, Weiss AC, Rudat C, Meuser M, Trowe MO, Kispert A, Diversification of Cell Lineages in Ureter Development. J Am Soc Nephrol. 2017 Jun;28(6):1792-1801 |
1 | J:244068 Bohnenpoll T, Wittern AB, Mamo TM, Weiss AC, Rudat C, Kleppa MJ, Schuster-Gossler K, Wojahn I, Ludtke TH, Trowe MO, Kispert A, A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development. PLoS Genet. 2017 Aug;13(8):e1006951 |
1 | J:235730 Byrd KM, Lough KJ, Patel JH, Descovich CP, Curtis TA, Williams SE, LGN plays distinct roles in oral epithelial stratification, filiform papilla morphogenesis and hair follicle development. Development. 2016 Aug 1;143(15):2803-17 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1* | J:288446 Christians A, Weiss AC, Martens H, Klopf MG, Hennies I, Haffner D, Kispert A, Weber RG, Inflammation-like changes in the urothelium of Lifr-deficient mice and LIFR-haploinsufficient humans with urinary tract anomalies. Hum Mol Genet. 2020 May 8;29(7):1192-1204 |
1 | J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767 |
1 | J:207252 Drosten M, Lechuga CG, Barbacid M, Ras signaling is essential for skin development. Oncogene. 2014 May 29;33(22):2857-65 |
1 | J:260456 Duteil D, Tourrette Y, Eberlin A, Willmann D, Patel D, Friedrichs N, Muller JM, Schule R, The histone acetyltransferase inhibitor Nir regulates epidermis development. Development. 2018 Mar 21;145(6):dev158543 |
2 | J:220467 Galvis LA, Holik AZ, Short KM, Pasquet J, Lun AT, Blewitt ME, Smyth IM, Ritchie ME, Asselin-Labat ML, Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung. Development. 2015 Apr 15;142(8):1458-69 |
1 | J:125817 Gordon J, Xiao S, Hughes B rd, Su DM, Navarre SP, Condie BG, Manley NR, Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus. BMC Dev Biol. 2007;7:69 |
1 | J:239161 Guo C, Balsara ZR, Hill WG, Li X, Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration. Development. 2017 Feb 01;144(3):400-408 |
1 | J:255577 Hsu WH, Chen CM, You LR, COUP-TFII is required for morphogenesis of the neural crest-derived tympanic ring. Sci Rep. 2017 Sep 28;7(1):12386 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:266277 Joseph DB, Chandrashekar AS, Abler LL, Chu LF, Thomson JA, Mendelsohn C, Vezina CM, In vivo replacement of damaged bladder urothelium by Wolffian duct epithelial cells. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):8394-8399 |
1* | J:331303 Kantzer CG, Yang W, Grommisch D, Patikl KV, Mak KH, Shirokova V, Genander M, ID1 and CEBPA coordinate epidermal progenitor cell differentiation. Development. 2022 Nov;149(22) |
1 | J:135131 Kashiwagi M, Morgan BA, Georgopoulos K, The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny. Development. 2007 Apr;134(8):1571-82 |
1 | J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47 |
1 | J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522 |
1 | J:261926 Kwon E, Todorova K, Wang J, Horos R, Lee KK, Neel VA, Negri GL, Sorensen PH, Lee SW, Hentze MW, Mandinova A, The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level. Nat Commun. 2018 Apr 30;9(1):1734 |
1* | J:281551 Laurin M, Gomez NC, Levorse J, Sendoel A, Sribour M, Fuchs E, An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis. Elife. 2019 Sep 25;8:e50226 |
1 | J:290414 Li J, Gordon J, Chen ELY, Xiao S, Wu L, Zuniga-Pflucker JC, Manley NR, NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development. Development. 2020 Jun 22;147(12):dev178988 |
1 | J:338836 Li Q, Jiao J, Heng Y, Lu Q, Zheng Y, Li H, Cai J, Mei M, Bao S, Prmt5 promotes ciliated cell specification of airway epithelial progenitors via transcriptional inhibition of Tp63. J Biol Chem. 2023 Jun 24;299(8):104964 |
1 | J:291487 Liu D, Kousa AI, O'Neill KE, Rouse P, Popis M, Farley AM, Tomlinson SR, Ulyanchenko S, Guillemot F, Seymour PA, Jorgensen MC, Serup P, Koch U, Radtke F, Blackburn CC, Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development. Development. 2020 Jun 22;147(12):dev178582 |
1 | J:219800 Lungova V, Verheyden JM, Herriges J, Sun X, Thibeault SL, Ontogeny of the mouse vocal fold epithelium. Dev Biol. 2015 Mar 15;399(2):263-82 |
1 | J:243772 Mamo TM, Wittern AB, Kleppa MJ, Bohnenpoll T, Weiss AC, Kispert A, BMP4 uses several different effector pathways to regulate proliferation and differentiation in the epithelial and mesenchymal tissue compartments of the developing mouse ureter. Hum Mol Genet. 2017 Sep 15;26(18):3553-3563 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1 | J:279389 Miao Q, Hill MC, Chen F, Mo Q, Ku AT, Ramos C, Sock E, Lefebvre V, Nguyen H, SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair. Nat Commun. 2019 Sep 6;10(1):4042 |
1* | J:306379 Mohad V, Lungova V, Verheyden J, Thibeault SL, Inactivation of Lats1 and Lats2 highlights the role of hippo pathway effector YAP in larynx and vocal fold epithelium morphogenesis. Dev Biol. 2021 May;473:33-49 |
1 | J:266862 Morosan-Puopolo G, Balakrishnan-Renuka A, Yusuf F, Chen J, Dai F, Zoidl G, Ludtke TH, Kispert A, Theiss C, Abdelsabour-Khalaf M, Brand-Saberi B, Wnt11 is required for oriented migration of dermogenic progenitor cells from the dorsomedial lip of the avian dermomyotome. PLoS One. 2014;9(3):e92679 |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
1 | J:171374 Osorio KM, Lilja KC, Tumbar T, Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol. 2011 Apr 4;193(1):235-50 |
2* | J:326663 Qasrawi F, Meuser M, Lehnhoff F, Schulte M, Kispert A, S100A1 expression characterizes terminally differentiated superficial cells in the urothelium of the murine bladder and ureter. Histochem Cell Biol. 2022 Jun 1; |
1 | J:149319 Romano RA, Ortt K, Birkaya B, Smalley K, Sinha S, An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate. PLoS One. 2009;4(5):e5623 |
1 | J:181275 Romano RA, Smalley K, Magraw C, Serna VA, Kurita T, Raghavan S, Sinha S, DeltaNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation. Development. 2012 Feb;139(4):772-82 |
1 | J:229900 Seldin L, Muroyama A, Lechler T, NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures. Elife. 2016;5:e12504 |
1 | J:186971 Shalom-Feuerstein R, Lena AM, Zhou H, De La Forest Divonne S, Van Bokhoven H, Candi E, Melino G, Aberdam D, DeltaNp63 is an ectodermal gatekeeper of epidermal morphogenesis. Cell Death Differ. 2011 May;18(5):887-96 |
2 | J:217677 Snitow ME, Li S, Morley MP, Rathi K, Lu MM, Kadzik RS, Stewart KM, Morrisey EE, Ezh2 represses the basal cell lineage during lung endoderm development. Development. 2015 Jan 1;142(1):108-17 |
1 | J:356070 Song EC, Min S, Oyelakin A, Smalley K, Bard JE, Liao L, Xu J, Romano RA, Genetic and scRNA-seq Analysis Reveals Distinct Cell Populations that Contribute to Salivary Gland Development and Maintenance. Sci Rep. 2018 Sep 19;8(1):14043 |
1 | J:290878 Sun X, Are A, Annusver K, Sivan U, Jacob T, Dalessandri T, Joost S, Fullgrabe A, Gerling M, Kasper M, Coordinated hedgehog signaling induces new hair follicles in adult skin. Elife. 2020 Mar 17;9:e46756 |
1 | J:194300 Suzuki J, Yoshizaki K, Kobayashi T, Osumi N, Neural crest-derived horizontal basal cells as tissue stem cells in the adult olfactory epithelium. Neurosci Res. 2013 Feb;75(2):112-20 |
1* | J:240534 Toivanen R, Shen MM, Prostate organogenesis: tissue induction, hormonal regulation and cell type specification. Development. 2017 Apr 15;144(8):1382-1398 |
1 | J:196491 Torchia EC, Zhang L, Huebner AJ, Sen S, Roop DR, Aurora kinase-A deficiency during skin development impairs cell division and stratification. J Invest Dermatol. 2013 Jan;133(1):78-86 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
1 | J:277336 Turco AE, Cadena MT, Zhang HL, Sandhu JK, Oakes SR, Chathurvedula T, Peterson RE, Keast JR, Vezina CM, A temporal and spatial map of axons in developing mouse prostate. Histochem Cell Biol. 2019 Jul;152(1):35-45 |
1 | J:338452 Wang D, Li H, Chandel NS, Dou Y, Yi R, MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters. Nat Commun. 2023 Jul 21;14(1):4404 |
1 | J:178707 Wang SK, Komatsu Y, Mishina Y, Potential contribution of neural crest cells to dental enamel formation. Biochem Biophys Res Commun. 2011 Nov 11;415(1):114-9 |
1* | J:180986 Wei Q, Condie BG, A focused in situ hybridization screen identifies candidate transcriptional regulators of thymic epithelial cell development and function. PLoS One. 2011;6(11):e26795 |
1 | J:114626 Yu Z, Lin KK, Bhandari A, Spencer JA, Xu X, Wang N, Lu Z, Gill GN, Roop DR, Wertz P, Andersen B, The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Dev Biol. 2006 Nov 1;299(1):122-36 |
1 | J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687 |
1 | J:146244 Zuklys S, Gill J, Keller MP, Hauri-Hohl M, Zhanybekova S, Balciunaite G, Na KJ, Jeker LT, Hafen K, Tsukamoto N, Amagai T, Taketo MM, Krenger W, Hollander GA, Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. J Immunol. 2009 Mar 1;182(5):2997-3007 |
Krt6 keratin 6 (Synonyms: K6, Krt-2.6, Krt2-6) | |
Results | Reference |
1 | J:346910 Ayyangar U, Karkhanis A, Tay H, Afandi AFB, Bhattacharjee O, Ks L, Lee SH, Chan J, Raghavan S, Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin. EMBO J. 2024 Apr;43(7):1113-1134 |
1 | J:80753 Bernot KM, Coulombe PA, McGowan KM, Keratin 16 expression defines a subset of epithelial cells during skin morphogenesis and the hair cycle. J Invest Dermatol. 2002 Nov;119(5):1137-49 |
1 | J:235730 Byrd KM, Lough KJ, Patel JH, Descovich CP, Curtis TA, Williams SE, LGN plays distinct roles in oral epithelial stratification, filiform papilla morphogenesis and hair follicle development. Development. 2016 Aug 1;143(15):2803-17 |
1 | J:259661 De Groote P, Tran HT, Fransen M, Tanghe G, Urwyler C, De Craene B, Leurs K, Gilbert B, Van Imschoot G, De Rycke R, Guerin CJ, Holland P, Berx G, Vandenabeele P, Lippens S, Vleminckx K, Declercq W, A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes. Cell Death Differ. 2015 Jun;22(6):1012-24 |
1 | J:135131 Kashiwagi M, Morgan BA, Georgopoulos K, The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny. Development. 2007 Apr;134(8):1571-82 |
1 | J:210514 Martinez P, Ferrara-Romeo I, Flores JM, Blasco MA, Essential role for the TRF2 telomere protein in adult skin homeostasis. Aging Cell. 2014 Aug;13(4):656-68 |
1* | J:66533 Mazzalupo S, Coulombe PA, A reporter transgene based on a human keratin 6 gene promoter is specifically expressed in the periderm of mouse embryos. Mech Dev. 2001 Jan;100(1):65-9 |
1* | J:50471 McGowan KM, Coulombe PA, Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development. J Cell Biol. 1998 Oct 19;143(2):469-86 |
1 | J:182928 Nagarajan P, Chin SS, Wang D, Liu S, Sinha S, Garrett-Sinha LA, Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators. J Cell Sci. 2010 Oct 15;123(Pt 20):3566-75 |
1 | J:192725 Okano J, Lichti U, Mamiya S, Aronova M, Zhang G, Yuspa SH, Hamada H, Sakai Y, Morasso MI, Increased retinoic acid levels through ablation of Cyp26b1 determine the processes of embryonic skin barrier formation and peridermal development. J Cell Sci. 2012 Apr 1;125(Pt 7):1827-36 |
1 | J:256217 Rubsam M, Mertz AF, Kubo A, Marg S, Jungst C, Goranci-Buzhala G, Schauss AC, Horsley V, Dufresne ER, Moser M, Ziegler W, Amagai M, Wickstrom SA, Niessen CM, E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning. Nat Commun. 2017 Nov 1;8(1):1250 |
1* | J:159506 Sun P, Yuan Y, Li A, Li B, Dai X, Cytokeratin expression during mouse embryonic and early postnatal mammary gland development. Histochem Cell Biol. 2010 Feb;133(2):213-21 |
1 | J:196491 Torchia EC, Zhang L, Huebner AJ, Sen S, Roop DR, Aurora kinase-A deficiency during skin development impairs cell division and stratification. J Invest Dermatol. 2013 Jan;133(1):78-86 |
1* | J:294158 Vernersson Lindahl E, Garcia EL, Mills AA, An allelic series of Trp63 mutations defines TAp63 as a modifier of EEC syndrome. Am J Med Genet A. 2013 Aug;161A(8):1961-71 |
1 | J:338452 Wang D, Li H, Chandel NS, Dou Y, Yi R, MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters. Nat Commun. 2023 Jul 21;14(1):4404 |
Krt6a keratin 6A (Synonyms: Krt2-6a, Krt2-6c, mK6[a], MK6a) | |
Results | Reference |
2* | J:129949 Cui CY, Kunisada M, Esibizione D, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet. 2007 Nov 1;16(21):2583-90 |
1 | J:121940 Grimm SL, Bu W, Longley MA, Roop DR, Li Y, Rosen JM, Keratin 6 is not essential for mammary gland development. Breast Cancer Res. 2006;8(3):R29 |
1 | J:311844 Landin MA, Nygard S, Shabestari MG, Babaie E, Reseland JE, Osmundsen H, Mapping the global mRNA transcriptome during development of the murine first molar. Front Genet. 2015;6:47 |
1* | J:66533 Mazzalupo S, Coulombe PA, A reporter transgene based on a human keratin 6 gene promoter is specifically expressed in the periderm of mouse embryos. Mech Dev. 2001 Jan;100(1):65-9 |
1* | J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903 |
Krt6b keratin 6B (Synonyms: Krt2-6b, mK6[b]) | |
Results | Reference |
1* | J:198837 Cui CY, Klar J, Georgii-Heming P, Frojmark AS, Baig SM, Schlessinger D, Dahl N, Frizzled6 deficiency disrupts the differentiation process of nail development. J Invest Dermatol. 2013 Aug;133(8):1990-7 |
1 | J:121940 Grimm SL, Bu W, Longley MA, Roop DR, Li Y, Rosen JM, Keratin 6 is not essential for mammary gland development. Breast Cancer Res. 2006;8(3):R29 |
1* | J:66533 Mazzalupo S, Coulombe PA, A reporter transgene based on a human keratin 6 gene promoter is specifically expressed in the periderm of mouse embryos. Mech Dev. 2001 Jan;100(1):65-9 |
Krt7 keratin 7 (Synonyms: Cytokeratin 7, D15Wsu77e, K7, Krt2-7) | |
Results | Reference |
1 | J:317045 Cheng W, Li HL, Xi SY, Zhang XF, Zhu Y, Le Xing, Mo YX, Li MM, Kong FE, Zhu WJ, Chen XG, Cui HQ, Cao ZM, Gong YF, Tang YQ, Zhang Y, Guan XY, Ma NF, Liu M, Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma. Nat Commun. 2021 Dec 8;12(1):7142 |
1 | J:168727 Furuyama K, Kawaguchi Y, Akiyama H, Horiguchi M, Kodama S, Kuhara T, Hosokawa S, Elbahrawy A, Soeda T, Koizumi M, Masui T, Kawaguchi M, Takaori K, Doi R, Nishi E, Kakinoki R, Deng JM, Behringer RR, Nakamura T, Uemoto S, Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet. 2011 Jan;43(1):34-41 |
1 | J:252735 Jiang M, Li H, Zhang Y, Yang Y, Lu R, Liu K, Lin S, Lan X, Wang H, Wu H, Zhu J, Zhou Z, Xu J, Lee DK, Zhang L, Lee YC, Yuan J, Abrams JA, Wang TC, Sepulveda AR, Wu Q, Chen H, Sun X, She J, Chen X, Que J, Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus. Nature. 2017 Oct 26;550(7677):529-533 |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
Krt8 keratin 8 (Synonyms: Card2, cytokeratin 8, cytokeratin-8, cytokeratin8, EndoA, K8, Krt-2.8, Krt2-8, TROMA-1) | |
Results | Reference |
1 | J:315767 Ahn SY, Kim Y, Kim ST, Swat W, Miner JH, Scaffolding proteins DLG1 and CASK cooperate to maintain the nephron progenitor population during kidney development. J Am Soc Nephrol. 2013 Jun;24(7):1127-38 |
1 | J:333984 Altes G, Vaquero M, Cuesta S, Anerillas C, Macia A, Espinet C, Ribera J, Bellusci S, Klein OD, Yeramian A, Dolcet X, Egea J, Encinas M, A dominant negative mutation uncovers cooperative control of caudal Wolffian duct development by Sprouty genes. Cell Mol Life Sci. 2022 Sep 13;79(10):514 |
1 | J:362029 Anjum H, Smith JP, Martini AG, Yacu GS, Medrano S, Gomez RA, Sequeira-Lopez MLS, Quaggin SE, Finer G, Tcf21 as a founder transcription factor in specifying Foxd1 cells to the juxtaglomerular cell lineage. Am J Physiol Renal Physiol. 2025 Jan 1;328(1):F121-F130 |
1 | J:185582 Barak H, Huh SH, Chen S, Jeanpierre C, Martinovic J, Parisot M, Bole-Feysot C, Nitschke P, Salomon R, Antignac C, Ornitz DM, Kopan R, FGF9 and FGF20 Maintain the Stemness of Nephron Progenitors in Mice and Man. Dev Cell. 2012 Jun 12;22(6):1191-207 |
1* | J:119780 Bazzi H, Fantauzzo KA, Richardson GD, Jahoda CA, Christiano AM, Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression. Dev Dyn. 2007 Mar 1;236(4):961-970 |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1 | J:106993 Briancon N, Weiss MC, In vivo role of the HNF4alpha AF-1 activation domain revealed by exon swapping. EMBO J. 2006 Mar 22;25(6):1253-62 |
1 | J:235730 Byrd KM, Lough KJ, Patel JH, Descovich CP, Curtis TA, Williams SE, LGN plays distinct roles in oral epithelial stratification, filiform papilla morphogenesis and hair follicle development. Development. 2016 Aug 1;143(15):2803-17 |
1 | J:186083 Calderon L, Boehm T, Synergistic, context-dependent, and hierarchical functions of epithelial components in thymic microenvironments. Cell. 2012 Mar 30;149(1):159-72 |
1 | J:349865 Carabana C, Sun W, Veludo Ramos C, Huyghe M, Perkins M, Maillot A, Journot R, Hartani F, Faraldo MM, Lloyd-Lewis B, Fre S, Spatially distinct epithelial and mesenchymal cell subsets along progressive lineage restriction in the branching embryonic mammary gland. EMBO J. 2024 Jun;43(12):2308-2336 |
1 | J:333004 Chatzeli L, Bordeu I, Han S, Bisetto S, Waheed Z, Koo BK, Alcolea MP, Simons BD, A cellular hierarchy of Notch and Kras signaling controls cell fate specification in the developing mouse salivary gland. Dev Cell. 2023 Jan 23;58(2):94-109.e6 |
1 | J:282828 Fan D, Chettouh Z, Consalez GG, Brunet JF, Taste bud formation depends on taste nerves. Elife. 2019 Oct 1;8:e49226 |
2 | J:316093 Golden EJ, Larson ED, Shechtman LA, Trahan GD, Gaillard D, Fellin TJ, Scott JK, Jones KL, Barlow LA, Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function. Elife. 2021 May 19;10:e64013 |
1 | J:280117 Gong X, Guo X, Huang R, Liao H, Zhang Q, Yan J, Luo L, Zhang Q, Qiu A, Sun Y, Liang X, Expression of ILK in renal stroma is essential for multiple aspects of renal development. Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F374-F385 |
1 | J:125817 Gordon J, Xiao S, Hughes B rd, Su DM, Navarre SP, Condie BG, Manley NR, Specific expression of lacZ and cre recombinase in fetal thymic epithelial cells by multiplex gene targeting at the Foxn1 locus. BMC Dev Biol. 2007;7:69 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1 | J:166890 Hofmann JJ, Zovein AC, Koh H, Radtke F, Weinmaster G, Iruela-Arispe ML, Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome. Development. 2010 Dec;137(23):4061-72 |
1 | J:275123 Jenkins BA, Fontecilla NM, Lu CP, Fuchs E, Lumpkin EA, The cellular basis of mechanosensory Merkel-cell innervation during development. Elife. 2019 Feb 22;8:e42633 |
1 | J:252735 Jiang M, Li H, Zhang Y, Yang Y, Lu R, Liu K, Lin S, Lan X, Wang H, Wu H, Zhu J, Zhou Z, Xu J, Lee DK, Zhang L, Lee YC, Yuan J, Abrams JA, Wang TC, Sepulveda AR, Wu Q, Chen H, Sun X, She J, Chen X, Que J, Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus. Nature. 2017 Oct 26;550(7677):529-533 |
1 | J:173588 Kanazawa T, Ichii O, Otsuka S, Namiki Y, Hashimoto Y, Kon Y, Hepatocyte nuclear factor 4 alpha is associated with mesenchymal-epithelial transition in developing kidneys of C57BL/6 mice. J Vet Med Sci. 2011 May;73(5):601-7 |
1* | J:326010 Kanda S, Ohmuraya M, Akagawa H, Horita S, Yoshida Y, Kaneko N, Sugawara N, Ishizuka K, Miura K, Harita Y, Yamamoto T, Oka A, Araki K, Furukawa T, Hattori M, Deletion in the Cobalamin Synthetase W Domain-Containing Protein 1 Gene Is associated with Congenital Anomalies of the Kidney and Urinary Tract. J Am Soc Nephrol. 2020 Jan;31(1):139-147 |
1 | J:353381 Kostic L, Leung C, Ahmad Murad K, Kancheva S, Perna S, Lee B, Barker N, Lgr5 marks stem/progenitor cells contributing to epithelial and muscle development in the mouse esophagus. Nat Commun. 2024 Aug 21;15(1):7145 |
2* | J:202344 Lesko MH, Driskell RR, Kretzschmar K, Goldie SJ, Watt FM, Sox2 modulates the function of two distinct cell lineages in mouse skin. Dev Biol. 2013 Oct 1;382(1):15-26 |
1 | J:306027 Li H, Kurtzeborn K, Kupari J, Gui Y, Siefker E, Lu B, Matlik K, Olfat S, Montano-Rodriguez AR, Huh SH, Costantini F, Andressoo JO, Kuure S, Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF. Development. 2021 May 15;148(10):dev197475 |
1 | J:290414 Li J, Gordon J, Chen ELY, Xiao S, Wu L, Zuniga-Pflucker JC, Manley NR, NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development. Development. 2020 Jun 22;147(12):dev178988 |
1 | J:291487 Liu D, Kousa AI, O'Neill KE, Rouse P, Popis M, Farley AM, Tomlinson SR, Ulyanchenko S, Guillemot F, Seymour PA, Jorgensen MC, Serup P, Koch U, Radtke F, Blackburn CC, Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development. Development. 2020 Jun 22;147(12):dev178582 |
1 | J:219800 Lungova V, Verheyden JM, Herriges J, Sun X, Thibeault SL, Ontogeny of the mouse vocal fold epithelium. Dev Biol. 2015 Mar 15;399(2):263-82 |
1 | J:258790 Lungova V, Verheyden JM, Sun X, Thibeault SL, beta-Catenin signaling is essential for mammalian larynx recanalization and the establishment of vocal fold progenitor cells. Development. 2018 Feb 16;145(4):dev157677 |
1* | J:263032 Magella B, Mahoney R, Adam M, Potter SS, Reduced Abd-B Hox function during kidney development results in lineage infidelity. Dev Biol. 2018 Jun 15;438(2):84-93 |
1 | J:207861 Manthey AL, Lachke SA, FitzGerald PG, Mason RW, Scheiblin DA, McDonald JH, Duncan MK, Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development. Mech Dev. 2014 Feb;131:86-110 |
1 | J:237697 Maurya DK, Henriques T, Marini M, Pedemonte N, Galietta LJ, Rock JR, Harfe BD, Menini A, Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice. PLoS One. 2015;10(6):e0129171 |
1* | J:81673 Mbiene JP, Roberts JD, Distribution of keratin 8-containing cell clusters in mouse embryonic tongue: Evidence for a prepattern for taste bud development. J Comp Neurol. 2003 Mar 3;457(2):111-22 |
1 | J:169431 Mikkola ML, Costanzo A, Thesleff I, Roop DR, Koster MI, Treasure or artifact: a decade of p63 research speaks for itself. Cell Death Differ. 2010 Jan;17(1):180-3; author reply 184-6 |
1* | J:306379 Mohad V, Lungova V, Verheyden J, Thibeault SL, Inactivation of Lats1 and Lats2 highlights the role of hippo pathway effector YAP in larynx and vocal fold epithelium morphogenesis. Dev Biol. 2021 May;473:33-49 |
1 | J:320686 Molina LM, Zhu J, Li Q, Pradhan-Sundd T, Krutsenko Y, Sayed K, Jenkins N, Vats R, Bhushan B, Ko S, Hu S, Poddar M, Singh S, Tao J, Sundd P, Singhi A, Watkins S, Ma X, Benos PV, Feranchak A, Michalopoulos G, Nejak-Bowen K, Watson A, Bell A, Monga SP, Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors. Cell Rep. 2021 Jul 6;36(1):109310 |
1* | J:154915 Morrison KM, Miesegaes GR, Lumpkin EA, Maricich SM, Mammalian Merkel cells are descended from the epidermal lineage. Dev Biol. 2009 Dec 1;336(1):76-83 |
1 | J:293206 Munoz JJ, Tobajas E, Juara S, Montero S, Zapata AG, FoxN1 mediates thymic cortex-medulla differentiation through modifying a developmental pattern based on epithelial tubulogenesis. Histochem Cell Biol. 2019 Dec;152(6):397-413 |
1 | J:267954 Nguyen MB, Cohen I, Kumar V, Xu Z, Bar C, Dauber-Decker KL, Tsai PC, Marangoni P, Klein OD, Hsu YC, Chen T, Mikkola ML, Ezhkova E, FGF signalling controls the specification of hair placode-derived SOX9 positive progenitors to Merkel cells. Nat Commun. 2018 Jun 13;9(1):2333 |
1 | J:298271 Nguyen MB, Valdes VJ, Cohen I, Pothula V, Zhao D, Zheng D, Ezhkova E, Dissection of Merkel cell formation in hairy and glabrous skin reveals a common requirement for FGFR2-mediated signalling. Exp Dermatol. 2019 Apr;28(4):374-382 |
1* | J:197594 Okubo T, Clark C, Hogan BL, Cell lineage mapping of taste bud cells and keratinocytes in the mouse tongue and soft palate. Stem Cells. 2009 Feb;27(2):442-50 |
1* | J:185947 Parisi I, Collinson JM, Regulation of Merkel cell development by Pax6. Int J Dev Biol. 2012;56(5):341-50 |
1* | J:332639 Rinta-Jaskari MM, Naillat F, Ruotsalainen HJ, Koivunen JT, Sasaki T, Pietila I, Elamaa HP, Kaur I, Manninen A, Vainio SJ, Pihlajaniemi TA, Temporally and Spatially Regulated Collagen XVIII Isoforms Are Involved in Ureteric Tree Development Via the TSP1-like Domain. Matrix Biol. 2023 Jan 6; |
1 | J:349014 Rinta-Jaskari MM, Naillat F, Ruotsalainen HJ, Ronkainen VP, Heljasvaara R, Akram SU, Izzi V, Miinalainen I, Vainio SJ, Pihlajaniemi TA, Collagen XVIII regulates extracellular matrix integrity in the developing nephrons and impacts nephron progenitor cell behavior. Matrix Biol. 2024 May 22; |
1 | J:181275 Romano RA, Smalley K, Magraw C, Serna VA, Kurita T, Raghavan S, Sinha S, DeltaNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation. Development. 2012 Feb;139(4):772-82 |
1 | J:277847 Roux M, Bouchard M, Kmita M, Multifaceted Hoxa13 function in urogenital development underlies the Hand-Foot-Genital Syndrome. Hum Mol Genet. 2019 May 15;28(10):1671-1681 |
1 | J:186971 Shalom-Feuerstein R, Lena AM, Zhou H, De La Forest Divonne S, Van Bokhoven H, Candi E, Melino G, Aberdam D, DeltaNp63 is an ectodermal gatekeeper of epidermal morphogenesis. Cell Death Differ. 2011 May;18(5):887-96 |
1 | J:331052 Sharma A, Meer M, Dapkunas A, Ihermann-Hella A, Kuure S, Vainio SJ, Iber D, Naillat F, FGF8 induces chemokinesis and regulates condensation of mouse nephron progenitor cells. Development. 2022 Nov 1;149(21):dev201012 |
1 | J:279029 Smith P, Godde N, Rubio S, Tekeste M, Vladar EK, Axelrod JD, Henderson DJ, Milgrom-Hoffman M, Humbert PO, Hinck L, VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland. Sci Rep. 2019 May 8;9(1):7079 |
1 | J:86789 Szeder V, Grim M, Kucera J, Sieber-Blum M, Neurotrophin-3 signaling in mammalian Merkel cell development. Dev Dyn. 2003 Dec;228(4):623-9 |
1 | J:263059 Tenno M, Kojo S, Lawir DF, Hess I, Shiroguchi K, Ebihara T, Endo TA, Muroi S, Satoh R, Kawamoto H, Boehm T, Taniuchi I, Cbfbeta2 controls differentiation of and confers homing capacity to prethymic progenitors. J Exp Med. 2018 Feb 5;215(2):595-610 |
1* | J:240534 Toivanen R, Shen MM, Prostate organogenesis: tissue induction, hormonal regulation and cell type specification. Development. 2017 Apr 15;144(8):1382-1398 |
2 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
1 | J:215769 Wang DH, Tiwari A, Kim ME, Clemons NJ, Regmi NL, Hodges WA, Berman DM, Montgomery EA, Watkins DN, Zhang X, Zhang Q, Jie C, Spechler SJ, Souza RF, Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia. J Clin Invest. 2014 Sep 2;124(9):3767-80 |
1 | J:234179 Xiao Y, Thoresen DT, Miao L, Williams JS, Wang C, Atit RP, Wong SY, Brownell I, A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development. PLoS Genet. 2016 Jul;12(7):e1006150 |
1 | J:363737 Xue Z, Xuan H, Lau K, Su Y, Wegener M, Li K, Turner L, Adams M, Shi X, Wen H, Expression of ENL YEATS domain tumor mutations in nephrogenic or stromal lineage impairs kidney development. Nat Commun. 2025 Mar 14;16(1):2531 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
1 | J:146244 Zuklys S, Gill J, Keller MP, Hauri-Hohl M, Zhanybekova S, Balciunaite G, Na KJ, Jeker LT, Hafen K, Tsukamoto N, Amagai T, Taketo MM, Krenger W, Hollander GA, Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. J Immunol. 2009 Mar 1;182(5):2997-3007 |
Krt10 keratin 10 (Synonyms: cytokeratin 10, D130054E02Rik, K10, K1C1, keratin 10, Krt-1.10, Krt1-10, suprabasal cytokeratin 10) | |
Results | Reference |
1 | J:235730 Byrd KM, Lough KJ, Patel JH, Descovich CP, Curtis TA, Williams SE, LGN plays distinct roles in oral epithelial stratification, filiform papilla morphogenesis and hair follicle development. Development. 2016 Aug 1;143(15):2803-17 |
1 | J:300611 Carper MB, Troutman S, Wagner BL, Byrd KM, Selitsky SR, Parag-Sharma K, Henry EC, Li W, Parker JS, Montgomery SA, Cleveland JL, Williams SE, Kissil JL, Hayes DN, Amelio AL, An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma. Cell Rep. 2019 Nov 5;29(6):1660-1674.e7 |
1 | J:272608 Cohen I, Zhao D, Menon G, Nakayama M, Koseki H, Zheng D, Ezhkova E, PRC1 preserves epidermal tissue integrity independently of PRC2. Genes Dev. 2019 Jan 1;33(1-2):55-60 |
1 | J:299752 Cottle DL, Ursino GMA, Jones LK, Tham MS, Zylberberg AK, Smyth IM, Topical Aminosalicylic Acid Improves Keratinocyte Differentiation in an Inducible Mouse Model of Harlequin Ichthyosis. Cell Rep Med. 2020 Nov 17;1(8):100129 |
1 | J:306061 Damen M, Wirtz L, Soroka E, Khatif H, Kukat C, Simons BD, Bazzi H, High proliferation and delamination during skin epidermal stratification. Nat Commun. 2021 May 28;12(1):3227 |
1 | J:207252 Drosten M, Lechuga CG, Barbacid M, Ras signaling is essential for skin development. Oncogene. 2014 May 29;33(22):2857-65 |
1 | J:260456 Duteil D, Tourrette Y, Eberlin A, Willmann D, Patel D, Friedrichs N, Muller JM, Schule R, The histone acetyltransferase inhibitor Nir regulates epidermis development. Development. 2018 Mar 21;145(6):dev158543 |
1* | J:123724 Golonzhka O, Leid M, Indra G, Indra AK, Expression of COUP-TF-interacting protein 2 (CTIP2) in mouse skin during development and in adulthood. Gene Expr Patterns. 2007 Aug;7(7):754-60 |
1 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
1 | J:304850 Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernandez-Baldovinos J, Zhou L, Hoss C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Grone HJ, Graumann PL, Niessen CM, Offermanns S, Wickstrom SA, Worzfeld T, Mechanochemical control of epidermal stem cell divisions by B-plexins. Nat Commun. 2021 Feb 26;12(1):1308 |
1* | J:94541 Jonker L, Kist R, Aw A, Wappler I, Peters H, Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium. Mech Dev. 2004 Nov;121(11):1313-22 |
1* | J:51300 Keeney DS, Skinner C, Travers JB, Capdevila JH, Nanney LB, King LE Jr, Waterman MR, Differentiating keratinocytes express a novel cytochrome P450 enzyme, CYP2B19, having arachidonate monooxygenase activity. J Biol Chem. 1998 Nov 27;273(48):32071-9 |
1 | J:263002 Komori T, Ono M, Hara ES, Ueda J, Nguyen HTT, Nguyen HT, Yonezawa T, Maeba T, Kimura-Ono A, Takarada T, Momota R, Maekawa K, Kuboki T, Oohashi T, Type IV collagen alpha6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium. Sci Rep. 2018 Feb 8;8(1):2612 |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
1 | J:277726 Lecland N, Hsu CY, Chemin C, Merdes A, Bierkamp C, Epidermal development requires ninein for spindle orientation and cortical microtubule organization. Life Sci Alliance. 2019 Apr;2(2) |
1 | J:54224 Lee D, Prowse DM, Brissette JL, Association between mouse nude gene expression and the initiation of epithelial terminal differentiation. Dev Biol. 1999 Apr 15;208(2):362-74 |
1* | J:255485 Li S, Teegarden A, Bauer EM, Choi J, Messaddeq N, Hendrix DA, Ganguli-Indra G, Leid M, Indra AK, Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development. Sci Rep. 2017 Oct 18;7(1):13427 |
1 | J:294113 Lough KJ, Byrd KM, Descovich CP, Spitzer DC, Bergman AJ, Beaudoin GM 3rd, Reichardt LF, Williams SE, Telophase correction refines division orientation in stratified epithelia. Elife. 2019 Dec 13;8:e49249 |
1 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
1 | J:210514 Martinez P, Ferrara-Romeo I, Flores JM, Blasco MA, Essential role for the TRF2 telomere protein in adult skin homeostasis. Aging Cell. 2014 Aug;13(4):656-68 |
1* | J:295958 Neupane S, Adhikari N, Jung JK, An CH, Lee S, Jun JH, Kim JY, Lee Y, Sohn WJ, Kim JY, Regulation of mesenchymal signaling in palatal mucosa differentiation. Histochem Cell Biol. 2018 Feb;149(2):143-152 |
1 | J:153617 O'Shaughnessy RF, Welti JC, Sully K, Byrne C, Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development. Development. 2009 Oct;136(20):3423-31 |
1 | J:309456 Pearson HB, McGlinn E, Phesse TJ, Schluter H, Srikumar A, Godde NJ, Woelwer CB, Ryan A, Phillips WA, Ernst M, Kaur P, Humbert P, The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis. Mol Cancer. 2015 Sep 17;14:169 |
1 | J:229900 Seldin L, Muroyama A, Lechler T, NuMA-microtubule interactions are critical for spindle orientation and the morphogenesis of diverse epidermal structures. Elife. 2016;5:e12504 |
1* | J:58009 Takaishi M, Huh Nh, A tetratricopeptide repeat-containing protein gene, tpis, whose expression is induced with differentiation of spermatogenic cells. Biochem Biophys Res Commun. 1999 Oct 14;264(1):81-5 |
2* | J:48444 Takaishi M, Takata Y, Kuroki T, Huh N, Isolation and characterization of a putative keratin-associated protein gene expressed in embryonic skin of mice. J Invest Dermatol. 1998 Jul;111(1):128-32 |
1 | J:196491 Torchia EC, Zhang L, Huebner AJ, Sen S, Roop DR, Aurora kinase-A deficiency during skin development impairs cell division and stratification. J Invest Dermatol. 2013 Jan;133(1):78-86 |
1* | J:294158 Vernersson Lindahl E, Garcia EL, Mills AA, An allelic series of Trp63 mutations defines TAp63 as a modifier of EEC syndrome. Am J Med Genet A. 2013 Aug;161A(8):1961-71 |
1 | J:359522 Villeneuve C, Hashmi A, Ylivinkka I, Lawson-Keister E, Miroshnikova YA, Perez-Gonzalez C, Myllymaki SM, Bertillot F, Yadav B, Zhang T, Matic Vignjevic D, Mikkola ML, Manning ML, Wickstrom SA, Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture. Nat Cell Biol. 2024 Feb;26(2):207-218 |
1 | J:114626 Yu Z, Lin KK, Bhandari A, Spencer JA, Xu X, Wang N, Lu Z, Gill GN, Roop DR, Wertz P, Andersen B, The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Dev Biol. 2006 Nov 1;299(1):122-36 |
1 | J:103004 Zhang H, Hara M, Seki K, Fukuda K, Nishida T, Eyelid fusion and epithelial differentiation at the ocular surface during mouse embryonic development. Jpn J Ophthalmol. 2005 May-Jun;49(3):195-204 |
2 | J:225082 Zhang LJ, Bhattacharya S, Leid M, Ganguli-Indra G, Indra AK, Ctip2 is a dynamic regulator of epidermal proliferation and differentiation by integrating EGFR and Notch signaling. J Cell Sci. 2012 Dec 1;125(Pt 23):5733-44 |
1 | J:141138 Zhang Y, Burgess D, Overbeek PA, Govindarajan V, Dominant inhibition of lens placode formation in mice. Dev Biol. 2008 Nov 1;323(1):53-63 |
Krt12 keratin 12 (Synonyms: K12, Krt1-12) | |
Results | Reference |
1 | J:228518 Arya P, Rainey MA, Bhattacharyya S, Mohapatra BC, George M, Kuracha MR, Storck MD, Band V, Govindarajan V, Band H, The endocytic recycling regulatory protein EHD1 Is required for ocular lens development. Dev Biol. 2015 Dec 1;408(1):41-55 |
1 | J:158529 Burgess D, Zhang Y, Siefker E, Vaca R, Kuracha MR, Reneker L, Overbeek PA, Govindarajan V, Activated Ras alters lens and corneal development through induction of distinct downstream targets. BMC Dev Biol. 2010;10:13 |
2 | J:99414 Chikama T, Hayashi Y, Liu CY, Terai N, Terai K, Kao CW, Wang L, Hayashi M, Nishida T, Sanford P, Doestchman T, Kao WW, Characterization of tetracycline-inducible bitransgenic Krt12rtTA/+/tet-O-LacZ mice. Invest Ophthalmol Vis Sci. 2005 Jun;46(6):1966-72 |
1 | J:223109 Choi JJ, Ting CT, Trogrlic L, Milevski SV, Familari M, Martinez G, de Iongh RU, A role for smoothened during murine lens and cornea development. PLoS One. 2014;9(9):e108037 |
1 | J:160411 Joo JH, Kim YH, Dunn NW, Sugrue SP, Disruption of mouse corneal epithelial differentiation by conditional inactivation of pnn. Invest Ophthalmol Vis Sci. 2010 Apr;51(4):1927-34 |
2* | J:73681 Saika S, Saika S, Liu CY, Azhar M, Sanford LP, Doetschman T, Gendron RL, Kao CW, Kao WW, TGFbeta2 in corneal morphogenesis during mouse embryonic development. Dev Biol. 2001 Dec 15;240(2):419-32 |
1* | J:65402 Yoshida N, Yoshida S, Araie M, Handa H, Nabeshima Y, Ets family transcription factor ESE-1 is expressed in corneal epithelial cells and is involved in their differentiation. Mech Dev. 2000 Oct;97(1-2):27-34 |
1 | J:103004 Zhang H, Hara M, Seki K, Fukuda K, Nishida T, Eyelid fusion and epithelial differentiation at the ocular surface during mouse embryonic development. Jpn J Ophthalmol. 2005 May-Jun;49(3):195-204 |
1 | J:242341 Zhang J, Upadhya D, Lu L, Reneker LW, Fibroblast growth factor receptor 2 (FGFR2) is required for corneal epithelial cell proliferation and differentiation during embryonic development. PLoS One. 2015;10(1):e0117089 |
1 | J:125580 Zhang L, Deng M, Kao CW, Kao WW, Xia Y, MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis. Mol Vis. 2003 Nov 3;9:584-93 |
1 | J:141138 Zhang Y, Burgess D, Overbeek PA, Govindarajan V, Dominant inhibition of lens placode formation in mice. Dev Biol. 2008 Nov 1;323(1):53-63 |
Krt13 keratin 13 (Synonyms: K13, Krt-1.13, Krt1-13) | |
Results | Reference |
1* | J:48444 Takaishi M, Takata Y, Kuroki T, Huh N, Isolation and characterization of a putative keratin-associated protein gene expressed in embryonic skin of mice. J Invest Dermatol. 1998 Jul;111(1):128-32 |
Krt14 keratin 14 (Synonyms: Cytokeratin 14, epidermolysis bullosa simplex, Dowling-Meara, Koebner, K14, Krt-1.14, Krt1-14) | |
Results | Reference |
1 | J:238285 Adolphe C, Junker JP, Lyubimova A, van Oudenaarden A, Wainwright B, Patched Receptors Sense, Interpret, and Establish an Epidermal Hedgehog Signaling Gradient. J Invest Dermatol. 2017 Jan;137(1):179-186 |
1 | J:80753 Bernot KM, Coulombe PA, McGowan KM, Keratin 16 expression defines a subset of epithelial cells during skin morphogenesis and the hair cycle. J Invest Dermatol. 2002 Nov;119(5):1137-49 |
1 | J:267642 Biggs LC, Makela OJ, Myllymaki SM, Das Roy R, Narhi K, Pispa J, Mustonen T, Mikkola ML, Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation. Elife. 2018 Jul 31;7:e36468 |
1 | J:158529 Burgess D, Zhang Y, Siefker E, Vaca R, Kuracha MR, Reneker L, Overbeek PA, Govindarajan V, Activated Ras alters lens and corneal development through induction of distinct downstream targets. BMC Dev Biol. 2010;10:13 |
1 | J:235730 Byrd KM, Lough KJ, Patel JH, Descovich CP, Curtis TA, Williams SE, LGN plays distinct roles in oral epithelial stratification, filiform papilla morphogenesis and hair follicle development. Development. 2016 Aug 1;143(15):2803-17 |
1 | J:300611 Carper MB, Troutman S, Wagner BL, Byrd KM, Selitsky SR, Parag-Sharma K, Henry EC, Li W, Parker JS, Montgomery SA, Cleveland JL, Williams SE, Kissil JL, Hayes DN, Amelio AL, An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma. Cell Rep. 2019 Nov 5;29(6):1660-1674.e7 |
1 | J:333004 Chatzeli L, Bordeu I, Han S, Bisetto S, Waheed Z, Koo BK, Alcolea MP, Simons BD, A cellular hierarchy of Notch and Kras signaling controls cell fate specification in the developing mouse salivary gland. Dev Cell. 2023 Jan 23;58(2):94-109.e6 |
1 | J:223109 Choi JJ, Ting CT, Trogrlic L, Milevski SV, Familari M, Martinez G, de Iongh RU, A role for smoothened during murine lens and cornea development. PLoS One. 2014;9(9):e108037 |
1 | J:191082 Clavel C, Grisanti L, Zemla R, Rezza A, Barros R, Sennett R, Mazloom AR, Chung CY, Cai X, Cai CL, Pevny L, Nicolis S, Ma'ayan A, Rendl M, Sox2 in the dermal papilla niche controls hair growth by fine-tuning BMP signaling in differentiating hair shaft progenitors. Dev Cell. 2012 Nov 13;23(5):981-94 |
1 | J:272608 Cohen I, Zhao D, Menon G, Nakayama M, Koseki H, Zheng D, Ezhkova E, PRC1 preserves epidermal tissue integrity independently of PRC2. Genes Dev. 2019 Jan 1;33(1-2):55-60 |
1 | J:299752 Cottle DL, Ursino GMA, Jones LK, Tham MS, Zylberberg AK, Smyth IM, Topical Aminosalicylic Acid Improves Keratinocyte Differentiation in an Inducible Mouse Model of Harlequin Ichthyosis. Cell Rep Med. 2020 Nov 17;1(8):100129 |
1* | J:129949 Cui CY, Kunisada M, Esibizione D, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet. 2007 Nov 1;16(21):2583-90 |
1 | J:217500 Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D, Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60 |
1 | J:152844 Driskell RR, Giangreco A, Jensen KB, Mulder KW, Watt FM, Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis. Development. 2009 Aug;136(16):2815-23 |
1 | J:260456 Duteil D, Tourrette Y, Eberlin A, Willmann D, Patel D, Friedrichs N, Muller JM, Schule R, The histone acetyltransferase inhibitor Nir regulates epidermis development. Development. 2018 Mar 21;145(6):dev158543 |
1 | J:194118 Fantauzzo KA, Kurban M, Levy B, Christiano AM, Trps1 and its target gene Sox9 regulate epithelial proliferation in the developing hair follicle and are associated with hypertrichosis. PLoS Genet. 2012;8(11):e1003002 |
1* | J:239434 Fleger-Weckmann A, Ustun Y, Kloepper J, Paus R, Bloch W, Chen ZL, Wegner J, Sorokin L, Langbein L, Eckes B, Zigrino P, Krieg T, Nischt R, Deletion of the epidermis derived laminin gamma1 chain leads to defects in the regulation of late hair morphogenesis. Matrix Biol. 2016 Dec;56:42-56 |
1 | J:334122 Glover JD, Sudderick ZR, Shih BB, Batho-Samblas C, Charlton L, Krause AL, Anderson C, Riddell J, Balic A, Li J, Klika V, Woolley TE, Gaffney EA, Corsinotti A, Anderson RA, Johnston LJ, Brown SJ, Wang S, Chen Y, Crichton ML, Headon DJ, The developmental basis of fingerprint pattern formation and variation. Cell. 2023 Mar 2;186(5):940-956.e20 |
1 | J:316093 Golden EJ, Larson ED, Shechtman LA, Trahan GD, Gaillard D, Fellin TJ, Scott JK, Jones KL, Barlow LA, Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function. Elife. 2021 May 19;10:e64013 |
1* | J:123724 Golonzhka O, Leid M, Indra G, Indra AK, Expression of COUP-TF-interacting protein 2 (CTIP2) in mouse skin during development and in adulthood. Gene Expr Patterns. 2007 Aug;7(7):754-60 |
2 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
1* | J:136080 Guttormsen J, Koster MI, Stevens JR, Roop DR, Williams T, Winger QA, Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice. Dev Biol. 2008 May 1;317(1):187-95 |
1 | J:112460 Hatsell SJ, Cowin P, Gli3-mediated repression of Hedgehog targets is required for normal mammary development. Development. 2006 Sep;133(18):3661-70 |
1 | J:83259 Jaubert J, Cheng J, Segre JA, Ectopic expression of kruppel like factor 4 (Klf4) accelerates formation of the epidermal permeability barrier. Development. 2003 Jun;130(12):2767-77 |
1 | J:282774 Jia X, Min L, Zhu S, Zhang S, Huang X, Loss of sonic hedgehog gene leads to muscle development disorder and megaesophagus in mice. FASEB J. 2018 Oct;32(10):5703-5715 |
1 | J:304850 Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernandez-Baldovinos J, Zhou L, Hoss C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Grone HJ, Graumann PL, Niessen CM, Offermanns S, Wickstrom SA, Worzfeld T, Mechanochemical control of epidermal stem cell divisions by B-plexins. Nat Commun. 2021 Feb 26;12(1):1308 |
1* | J:331303 Kantzer CG, Yang W, Grommisch D, Patikl KV, Mak KH, Shirokova V, Genander M, ID1 and CEBPA coordinate epidermal progenitor cell differentiation. Development. 2022 Nov;149(22) |
3 | J:257613 Kuony A, Michon F, Epithelial Markers aSMA, Krt14, and Krt19 Unveil Elements of Murine Lacrimal Gland Morphogenesis and Maturation. Front Physiol. 2017;8:739 |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
1 | J:213415 Lee B, Villarreal-Ponce A, Fallahi M, Ovadia J, Sun P, Yu QC, Ito S, Sinha S, Nie Q, Dai X, Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells. Dev Cell. 2014 Apr 14;29(1):47-58 |
1* | J:202344 Lesko MH, Driskell RR, Kretzschmar K, Goldie SJ, Watt FM, Sox2 modulates the function of two distinct cell lineages in mouse skin. Dev Biol. 2013 Oct 1;382(1):15-26 |
1 | J:72550 Li C, Guo H, Xu X, Weinberg W, Deng CX, Fibroblast growth factor receptor 2 (Fgfr2) plays an important role in eyelid and skin formation and patterning. Dev Dyn. 2001 Nov;222(3):471-83 |
1 | J:290414 Li J, Gordon J, Chen ELY, Xiao S, Wu L, Zuniga-Pflucker JC, Manley NR, NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development. Development. 2020 Jun 22;147(12):dev178988 |
1* | J:255485 Li S, Teegarden A, Bauer EM, Choi J, Messaddeq N, Hendrix DA, Ganguli-Indra G, Leid M, Indra AK, Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development. Sci Rep. 2017 Oct 18;7(1):13427 |
1 | J:352165 Lin Y, Tang W, Huang P, Wang Z, Duan L, Jia C, Sun R, Liu L, Shen J, Denticleless E3 ubiquitin protein ligase (DTL) maintains the proliferation and differentiation of epidermis and hair follicles during skin development. Dev Dyn. 2024 Jul;253(7):635-647 |
1 | J:291487 Liu D, Kousa AI, O'Neill KE, Rouse P, Popis M, Farley AM, Tomlinson SR, Ulyanchenko S, Guillemot F, Seymour PA, Jorgensen MC, Serup P, Koch U, Radtke F, Blackburn CC, Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development. Development. 2020 Jun 22;147(12):dev178582 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:219800 Lungova V, Verheyden JM, Herriges J, Sun X, Thibeault SL, Ontogeny of the mouse vocal fold epithelium. Dev Biol. 2015 Mar 15;399(2):263-82 |
1* | J:73258 Makino T, Takaishi M, Morohashi M, Huh NH, Hornerin, a novel profilaggrin-like protein and differentiation-specific marker isolated from mouse skin. J Biol Chem. 2001 Dec 14;276(50):47445-52 |
1 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
1 | J:210514 Martinez P, Ferrara-Romeo I, Flores JM, Blasco MA, Essential role for the TRF2 telomere protein in adult skin homeostasis. Aging Cell. 2014 Aug;13(4):656-68 |
1* | J:316269 Mehta V, Schmitz CT, Keil KP, Joshi PS, Abler LL, Lin TM, Taketo MM, Sun X, Vezina CM, Beta-catenin (CTNNB1) induces Bmp expression in urogenital sinus epithelium and participates in prostatic bud initiation and patterning. Dev Biol. 2013 Apr 15;376(2):125-35 |
1 | J:175603 Mejetta S, Morey L, Pascual G, Kuebler B, Mysliwiec MR, Lee Y, Shiekhattar R, Di Croce L, Benitah SA, Jarid2 regulates mouse epidermal stem cell activation and differentiation. EMBO J. 2011;30(17):3635-46 |
1 | J:169431 Mikkola ML, Costanzo A, Thesleff I, Roop DR, Koster MI, Treasure or artifact: a decade of p63 research speaks for itself. Cell Death Differ. 2010 Jan;17(1):180-3; author reply 184-6 |
1* | J:117240 Netzel-Arnett S, Currie BM, Szabo R, Lin CY, Chen LM, Chai KX, Antalis TM, Bugge TH, List K, Evidence for a matriptase-prostasin proteolytic cascade regulating terminal epidermal differentiation. J Biol Chem. 2006 Nov 3;281(44):32941-5 |
1 | J:122775 O'Shaughnessy RF, Welti JC, Cooke JC, Avilion AA, Monks B, Birnbaum MJ, Byrne C, AKT-dependent HspB1 (Hsp27) activity in epidermal differentiation. J Biol Chem. 2007 Jun 8;282(23):17297-305 |
1* | J:197594 Okubo T, Clark C, Hogan BL, Cell lineage mapping of taste bud cells and keratinocytes in the mouse tongue and soft palate. Stem Cells. 2009 Feb;27(2):442-50 |
1 | J:171374 Osorio KM, Lilja KC, Tumbar T, Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol. 2011 Apr 4;193(1):235-50 |
1 | J:173538 Packard A, Schnittke N, Romano RA, Sinha S, Schwob JE, {Delta}Np63 regulates stem cell dynamics in the Mammalian olfactory epithelium. J Neurosci. 2011 Jun 15;31(24):8748-59 |
1 | J:239882 Papafotiou G, Paraskevopoulou V, Vasilaki E, Kanaki Z, Paschalidis N, Klinakis A, KRT14 marks a subpopulation of bladder basal cells with pivotal role in regeneration and tumorigenesis. Nat Commun. 2016 Jun 20;7:11914 |
1* | J:85732 Petiot A, Conti FJ, Grose R, Revest JM, Hodivala-Dilke KM, Dickson C, A crucial role for Fgfr2-IIIb signalling in epidermal development and hair follicle patterning. Development. 2003 Nov;130(22):5493-501 |
1* | J:98380 Petiot A, Perriton CL, Dickson C, Cohn MJ, Development of the mammalian urethra is controlled by Fgfr2-IIIb. Development. 2005 May;132(10):2441-50 |
1* | J:73292 Ridanpaa M, Fodde R, Kielman M, Dynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structures. Mech Dev. 2001 Dec;109(2):173-81 |
1 | J:256852 Rinaldi L, Avgustinova A, Martin M, Datta D, Solanas G, Prats N, Benitah SA, Loss of Dnmt3a and Dnmt3b does not affect epidermal homeostasis but promotes squamous transformation through PPAR-gamma. Elife. 2017 Apr 20;6:e21697 |
1 | J:149319 Romano RA, Ortt K, Birkaya B, Smalley K, Sinha S, An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate. PLoS One. 2009;4(5):e5623 |
1 | J:182209 Schulz C, Gomez Perdiguero E, Chorro L, Szabo-Rogers H, Cagnard N, Kierdorf K, Prinz M, Wu B, Jacobsen SE, Pollard JW, Frampton J, Liu KJ, Geissmann F, A lineage of myeloid cells independent of Myb and hematopoietic stem cells. Science. 2012 Apr 6;336(6077):86-90 |
1 | J:341642 Schwartz B, Levi H, Menon G, Maria R, Upcher A, Kotlovski Y, Oss-Ronen L, Cohen I, ZNF750 Regulates Skin Barrier Function by Driving Cornified Envelope and Lipid Processing Pathways. J Invest Dermatol. 2023 Sep 3; |
1 | J:237499 Sima J, Piao Y, Chen Y, Schlessinger D, Molecular dynamics of Dkk4 modulates Wnt action and regulates meibomian gland development. Development. 2016 Dec 15;143(24):4723-4735 |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
1 | J:279029 Smith P, Godde N, Rubio S, Tekeste M, Vladar EK, Axelrod JD, Henderson DJ, Milgrom-Hoffman M, Humbert PO, Hinck L, VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland. Sci Rep. 2019 May 8;9(1):7079 |
2 | J:217677 Snitow ME, Li S, Morley MP, Rathi K, Lu MM, Kadzik RS, Stewart KM, Morrisey EE, Ezh2 represses the basal cell lineage during lung endoderm development. Development. 2015 Jan 1;142(1):108-17 |
1 | J:356070 Song EC, Min S, Oyelakin A, Smalley K, Bard JE, Liao L, Xu J, Romano RA, Genetic and scRNA-seq Analysis Reveals Distinct Cell Populations that Contribute to Salivary Gland Development and Maintenance. Sci Rep. 2018 Sep 19;8(1):14043 |
1* | J:159506 Sun P, Yuan Y, Li A, Li B, Dai X, Cytokeratin expression during mouse embryonic and early postnatal mammary gland development. Histochem Cell Biol. 2010 Feb;133(2):213-21 |
2* | J:48444 Takaishi M, Takata Y, Kuroki T, Huh N, Isolation and characterization of a putative keratin-associated protein gene expressed in embryonic skin of mice. J Invest Dermatol. 1998 Jul;111(1):128-32 |
1 | J:98520 Takamoto N, You LR, Moses K, Chiang C, Zimmer WE, Schwartz RJ, Demayo FJ, Tsai MJ, Tsai SY, COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development. 2005 May;132(9):2179-89 |
1 | J:181138 Taylor DK, Bubier JA, Silva KA, Sundberg JP, Development, structure, and keratin expression in C57BL/6J mouse eccrine glands. Vet Pathol. 2012 Jan;49(1):146-54 |
1 | J:196491 Torchia EC, Zhang L, Huebner AJ, Sen S, Roop DR, Aurora kinase-A deficiency during skin development impairs cell division and stratification. J Invest Dermatol. 2013 Jan;133(1):78-86 |
1* | J:117802 Troy TC, Li Y, O'malley L, Turksen K, The temporal and spatial expression of Claudins in epidermal development and the accelerated program of epidermal differentiation in K14-CaSR transgenic mice. Gene Expr Patterns. 2007 Feb;7(4):423-30 |
1 | J:282279 Ustun Y, Reibetanz M, Brachvogel B, Nischt R, Eckes B, Zigrino P, Krieg T, Dual role of laminin511 in regulating melanocyte migration and differentiation. Matrix Biol. 2019 Jul;80:59-71 |
1 | J:261303 Van Nostrand JL, Bowen ME, Vogel H, Barna M, Attardi LD, The p53 family members have distinct roles during mammalian embryonic development. Cell Death Differ. 2017 Apr;24(4):575-579 |
1 | J:101266 Vaziri Sani F, Hallberg K, Harfe BD, McMahon AP, Linde A, Gritli-Linde A, Fate-mapping of the epithelial seam during palatal fusion rules out epithelial-mesenchymal transformation. Dev Biol. 2005 Sep 15;285(2):490-5 |
1* | J:294158 Vernersson Lindahl E, Garcia EL, Mills AA, An allelic series of Trp63 mutations defines TAp63 as a modifier of EEC syndrome. Am J Med Genet A. 2013 Aug;161A(8):1961-71 |
1* | J:134349 Vezina CM, Allgeier SH, Fritz WA, Moore RW, Strerath M, Bushman W, Peterson RE, Retinoic acid induces prostatic bud formation. Dev Dyn. 2008 May;237(5):1321-33 |
1 | J:359522 Villeneuve C, Hashmi A, Ylivinkka I, Lawson-Keister E, Miroshnikova YA, Perez-Gonzalez C, Myllymaki SM, Bertillot F, Yadav B, Zhang T, Matic Vignjevic D, Mikkola ML, Manning ML, Wickstrom SA, Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture. Nat Cell Biol. 2024 Feb;26(2):207-218 |
1 | J:215769 Wang DH, Tiwari A, Kim ME, Clemons NJ, Regmi NL, Hodges WA, Berman DM, Montgomery EA, Watkins DN, Zhang X, Zhang Q, Jie C, Spechler SJ, Souza RF, Hedgehog signaling regulates FOXA2 in esophageal embryogenesis and Barrett's metaplasia. J Clin Invest. 2014 Sep 2;124(9):3767-80 |
1 | J:348702 Wang Q, Zeng S, Liang Y, Zhou R, Wang D, ASH2L Mediates Epidermal Differentiation and Hair Follicle Morphogenesis through H3K4me3 Modification. J Invest Dermatol. 2024 Apr 4; |
1 | J:169856 Xin Y, Lu Q, Li Q, IKK1 Control of Epidermal Differentiation Is Modulated by Notch Signaling. Am J Pathol. 2011 Apr;178(4):1568-77 |
1 | J:103004 Zhang H, Hara M, Seki K, Fukuda K, Nishida T, Eyelid fusion and epithelial differentiation at the ocular surface during mouse embryonic development. Jpn J Ophthalmol. 2005 May-Jun;49(3):195-204 |
1 | J:242341 Zhang J, Upadhya D, Lu L, Reneker LW, Fibroblast growth factor receptor 2 (FGFR2) is required for corneal epithelial cell proliferation and differentiation during embryonic development. PLoS One. 2015;10(1):e0117089 |
1 | J:125580 Zhang L, Deng M, Kao CW, Kao WW, Xia Y, MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis. Mol Vis. 2003 Nov 3;9:584-93 |
1 | J:225082 Zhang LJ, Bhattacharya S, Leid M, Ganguli-Indra G, Indra AK, Ctip2 is a dynamic regulator of epidermal proliferation and differentiation by integrating EGFR and Notch signaling. J Cell Sci. 2012 Dec 1;125(Pt 23):5733-44 |
Krt15 keratin 15 (Synonyms: K15, Krt1-15) | |
Results | Reference |
1 | J:170886 Fujiwara H, Ferreira M, Donati G, Marciano DK, Linton JM, Sato Y, Hartner A, Sekiguchi K, Reichardt LF, Watt FM, The basement membrane of hair follicle stem cells is a muscle cell niche. Cell. 2011 Feb 18;144(4):577-89 |
1 | J:356109 Ge W, Tan SJ, Wang SH, Li L, Sun XF, Shen W, Wang X, Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development. Theranostics. 2020;10(17):7581-7598 |
1 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
1 | J:324116 Morita R, Sanzen N, Sasaki H, Hayashi T, Umeda M, Yoshimura M, Yamamoto T, Shibata T, Abe T, Kiyonari H, Furuta Y, Nikaido I, Fujiwara H, Tracing the origin of hair follicle stem cells. Nature. 2021 Jun;594(7864):547-552 |
1 | J:209671 Tai G, Ranjzad P, Marriage F, Rehman S, Denley H, Dixon J, Mitchell K, Day PJ, Woolf AS, Cytokeratin 15 marks basal epithelia in developing ureters and is upregulated in a subset of urothelial cell carcinomas. PLoS One. 2013;8(11):e81167 |
1* | J:306034 Troy TC, Arabzadeh A, Turksen K, Re-assessing K15 as an epidermal stem cell marker. Stem Cell Rev Rep. 2011 Nov;7(4):927-34 |
Krt16 keratin 16 (Synonyms: K16, Krt1-16) | |
Results | Reference |
1 | J:80753 Bernot KM, Coulombe PA, McGowan KM, Keratin 16 expression defines a subset of epithelial cells during skin morphogenesis and the hair cycle. J Invest Dermatol. 2002 Nov;119(5):1137-49 |
Krt17 keratin 17 (Synonyms: K17, Krt1-17) | |
Results | Reference |
1 | J:80753 Bernot KM, Coulombe PA, McGowan KM, Keratin 16 expression defines a subset of epithelial cells during skin morphogenesis and the hair cycle. J Invest Dermatol. 2002 Nov;119(5):1137-49 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:111051 Cui CY, Hashimoto T, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9142-7 |
1 | J:259661 De Groote P, Tran HT, Fransen M, Tanghe G, Urwyler C, De Craene B, Leurs K, Gilbert B, Van Imschoot G, De Rycke R, Guerin CJ, Holland P, Berx G, Vandenabeele P, Lippens S, Vleminckx K, Declercq W, A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes. Cell Death Differ. 2015 Jun;22(6):1012-24 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:275123 Jenkins BA, Fontecilla NM, Lu CP, Fuchs E, Lumpkin EA, The cellular basis of mechanosensory Merkel-cell innervation during development. Elife. 2019 Feb 22;8:e42633 |
1 | J:308704 Kiyokawa H, Yamaoka A, Matsuoka C, Tokuhara T, Abe T, Morimoto M, Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfbeta-Id2 axis, for tissue regeneration. Dev Cell. 2021 Jul 12;56(13):1917-1929.e9 |
1 | J:188148 Landin MA, Shabestari M, Babaie E, Reseland JE, Osmundsen H, Gene Expression Profiling during Murine Tooth Development. Front Genet. 2012;3:139 |
1* | J:50471 McGowan KM, Coulombe PA, Onset of keratin 17 expression coincides with the definition of major epithelial lineages during skin development. J Cell Biol. 1998 Oct 19;143(2):469-86 |
1 | J:171374 Osorio KM, Lilja KC, Tumbar T, Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol. 2011 Apr 4;193(1):235-50 |
1 | J:141958 Yang SH, Andl T, Grachtchouk V, Wang A, Liu J, Syu LJ, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA, Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta-catenin signaling. Nat Genet. 2008 Sep 1;40(9):1130-5 |
Krt18 keratin 18 (Synonyms: CK18, Endo B, K18, Krt1-18) | |
Results | Reference |
1* | J:50678 Appert A, Fridmacher V, Locquet O, Magre S, Patterns of keratins 8, 18 and 19 during gonadal differentiation in the mouse: sex- and time-dependent expression of keratin 19. Differentiation. 1998 Sep;63(5):273-84 |
1* | J:119780 Bazzi H, Fantauzzo KA, Richardson GD, Jahoda CA, Christiano AM, Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression. Dev Dyn. 2007 Mar 1;236(4):961-970 |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
1 | J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1 | J:195630 Krolewski RC, Packard A, Jang W, Wildner H, Schwob JE, Ascl1 (Mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium. PLoS One. 2012;7(12):e51737 |
1 | J:332513 Laporte E, De Vriendt S, Hoekx J, Vankelecom H, Interleukin-6 is dispensable in pituitary normal development and homeostasis but needed for pituitary stem cell activation following local injury. Front Endocrinol (Lausanne). 2022;13:1092063 |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
1 | J:219800 Lungova V, Verheyden JM, Herriges J, Sun X, Thibeault SL, Ontogeny of the mouse vocal fold epithelium. Dev Biol. 2015 Mar 15;399(2):263-82 |
1 | J:169431 Mikkola ML, Costanzo A, Thesleff I, Roop DR, Koster MI, Treasure or artifact: a decade of p63 research speaks for itself. Cell Death Differ. 2010 Jan;17(1):180-3; author reply 184-6 |
1 | J:159267 Plante J, Simard M, Rantakari P, Cote M, Provost PR, Poutanen M, Tremblay Y, Epithelial cells are the major site of hydroxysteroid (17beta) dehydrogenase 2 and androgen receptor expression in fetal mouse lungs during the period overlapping the surge of surfactant. J Steroid Biochem Mol Biol. 2009 Nov;117(4-5):139-45 |
1 | J:186971 Shalom-Feuerstein R, Lena AM, Zhou H, De La Forest Divonne S, Van Bokhoven H, Candi E, Melino G, Aberdam D, DeltaNp63 is an ectodermal gatekeeper of epidermal morphogenesis. Cell Death Differ. 2011 May;18(5):887-96 |
1* | J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903 |
1 | J:316098 Zhao J, Lu P, Wan C, Huang Y, Cui M, Yang X, Hu Y, Zheng Y, Dong J, Wang M, Zhang S, Liu Z, Bian S, Wang X, Wang R, Ren S, Wang D, Yao Z, Chang G, Tang F, Zhao XY, Cell-fate transition and determination analysis of mouse male germ cells throughout development. Nat Commun. 2021 Nov 25;12(1):6839 |
1* | J:63747 Zuklys S, Balciunaite G, Agarwal A, Fasler-Kan E, Palmer E, Hollander GA, Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). J Immunol. 2000 Aug 15;165(4):1976-83 |
Krt19 keratin 19 (Synonyms: cytokeratin 19, cytokeratin-19, cytokeratin19, EndoC, K19, Krt-1.19, Krt1-19, MGC:25344) | |
Results | Reference |
1* | J:50678 Appert A, Fridmacher V, Locquet O, Magre S, Patterns of keratins 8, 18 and 19 during gonadal differentiation in the mouse: sex- and time-dependent expression of keratin 19. Differentiation. 1998 Sep;63(5):273-84 |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:317045 Cheng W, Li HL, Xi SY, Zhang XF, Zhu Y, Le Xing, Mo YX, Li MM, Kong FE, Zhu WJ, Chen XG, Cui HQ, Cao ZM, Gong YF, Tang YQ, Zhang Y, Guan XY, Ma NF, Liu M, Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma. Nat Commun. 2021 Dec 8;12(1):7142 |
1 | J:337474 Cobo I, Paliwal S, Bodas C, Felipe I, Melia-Aloma J, Torres A, Martinez-Villarreal J, Malumbres M, Garcia F, Millan I, Del Pozo N, Park JC, MacDonald RJ, Munoz J, Mendez R, Real FX, NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation. Nat Commun. 2023 Jun 23;14(1):3761 |
2 | J:346123 Darrigrand JF, Salowka A, Torres-Cano A, Tapia-Rojo R, Zhu T, Garcia-Manyes S, Spagnoli FM, Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner. Dev Cell. 2024 Feb 5;59(3):326-338.e5 |
1 | J:243698 Decaens T, Godard C, de Reynies A, Rickman DS, Tronche F, Couty JP, Perret C, Colnot S, Stabilization of beta-catenin affects mouse embryonic liver growth and hepatoblast fate. Hepatology. 2008 Jan;47(1):247-58 |
2 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1 | J:283354 Guiu J, Hannezo E, Yui S, Demharter S, Ulyanchenko S, Maimets M, Jorgensen A, Perlman S, Lundvall L, Mamsen LS, Larsen A, Olesen RH, Andersen CY, Thuesen LL, Hare KJ, Pers TH, Khodosevich K, Simons BD, Jensen KB, Tracing the origin of adult intestinal stem cells. Nature. 2019 Jun;570(7759):107-111 |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
2 | J:166890 Hofmann JJ, Zovein AC, Koh H, Radtke F, Weinmaster G, Iruela-Arispe ML, Jagged1 in the portal vein mesenchyme regulates intrahepatic bile duct development: insights into Alagille syndrome. Development. 2010 Dec;137(23):4061-72 |
1 | J:120218 Ito A, Nishikawa Y, Ohnuma K, Ohnuma I, Koma Y, Sato A, Enomoto K, Tsujimura T, Yokozaki H, SgIGSF is a novel biliary-epithelial cell adhesion molecule mediating duct/ductule development. Hepatology. 2007 Mar;45(3):684-94 |
1 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
3 | J:257613 Kuony A, Michon F, Epithelial Markers aSMA, Krt14, and Krt19 Unveil Elements of Murine Lacrimal Gland Morphogenesis and Maturation. Front Physiol. 2017;8:739 |
1 | J:240786 Lee DH, Park JO, Kim TS, Kim SK, Kim TH, Kim MC, Park GS, Kim JH, Kuninaka S, Olson EN, Saya H, Kim SY, Lee H, Lim DS, LATS-YAP/TAZ controls lineage specification by regulating TGFbeta signaling and Hnf4alpha expression during liver development. Nat Commun. 2016 Jun 30;7:11961 |
1 | J:330439 Liu H, He L, Cheng Q, Luo W, Zhao T, Yang D, Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states. Int J Mol Med. 2022 Nov;50(5) |
1* | J:10364 Lussier M, Ouellet T, Lampron C, Lapointe L, Royal A, Mouse keratin 19: complete amino acid sequence and gene expression during development. Gene. 1989 Dec 28;85(2):435-44 |
1 | J:318016 Otani S, Kakinuma S, Kamiya A, Goto F, Kaneko S, Miyoshi M, Tsunoda T, Asano Y, Kawai-Kitahata F, Nitta S, Nakata T, Okamoto R, Itsui Y, Nakagawa M, Azuma S, Asahina Y, Yamaguchi T, Koshikawa N, Seiki M, Nakauchi H, Watanabe M, Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells. Biochem Biophys Res Commun. 2016 Jan 22;469(4):1062-8 |
1 | J:221216 Takashima Y, Terada M, Kawabata M, Suzuki A, Dynamic three-dimensional morphogenesis of intrahepatic bile ducts in mouse liver development. Hepatology. 2015 Mar;61(3):1003-11 |
1* | J:152812 Tanaka M, Okabe M, Suzuki K, Kamiya Y, Tsukahara Y, Saito S, Miyajima A, Mouse hepatoblasts at distinct developmental stages are characterized by expression of EpCAM and DLK1: drastic change of EpCAM expression during liver development. Mech Dev. 2009 Aug-Sep;126(8-9):665-76 |
1 | J:362739 Wu Y, Qin K, Xu Y, Rajhans S, Vo T, Lopez KM, Liu J, Nipper MH, Deng J, Yin X, Ramjit LR, Ye Z, Luan Y, Arda HE, Wang P, Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation. Elife. 2024 Jul 25;13 |
1* | J:272566 Yang R, Wang H, Kang B, Chen B, Shi Y, Yang S, Sun L, Liu Y, Xiao W, Zhang T, Yang J, Zhang Y, Zhu M, Xu P, Chang Y, Jia Y, Huang Y, CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Krt20 keratin 20 (Synonyms: 9030623C06Rik, CK20, cytokeratin 20) | |
Results | Reference |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1 | J:283354 Guiu J, Hannezo E, Yui S, Demharter S, Ulyanchenko S, Maimets M, Jorgensen A, Perlman S, Lundvall L, Mamsen LS, Larsen A, Olesen RH, Andersen CY, Thuesen LL, Hare KJ, Pers TH, Khodosevich K, Simons BD, Jensen KB, Tracing the origin of adult intestinal stem cells. Nature. 2019 Jun;570(7759):107-111 |
1 | J:298271 Nguyen MB, Valdes VJ, Cohen I, Pothula V, Zhao D, Zheng D, Ezhkova E, Dissection of Merkel cell formation in hairy and glabrous skin reveals a common requirement for FGFR2-mediated signalling. Exp Dermatol. 2019 Apr;28(4):374-382 |
1* | J:185947 Parisi I, Collinson JM, Regulation of Merkel cell development by Pax6. Int J Dev Biol. 2012;56(5):341-50 |
1 | J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26 |
Krt23 keratin 23 (Synonyms: CK23, K23, Krt1-23) | |
Results | Reference |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
Krt28 keratin 28 (Synonyms: 4733401L19Rik) | |
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1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
Krt33b keratin 33B (Synonyms: Ha3, Ha4, Krt1-3, mHa3) | |
Results | Reference |
1* | J:58632 Meier N, Dear TN, Boehm T, Whn and mHa3 are components of the genetic hierarchy controlling hair follicle differentiation. Mech Dev. 1999 Dec;89(1-2):215-21 |
Krt35 keratin 35 (Synonyms: Ha5, Krt1-24) | |
Results | Reference |
1* | J:94541 Jonker L, Kist R, Aw A, Wappler I, Peters H, Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium. Mech Dev. 2004 Nov;121(11):1313-22 |
Krt36 keratin 36 (Synonyms: HRa-1, keratin 5, Krt1-22, Krt1-5) | |
Results | Reference |
1* | J:94541 Jonker L, Kist R, Aw A, Wappler I, Peters H, Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium. Mech Dev. 2004 Nov;121(11):1313-22 |
Krt77 keratin 77 (Synonyms: 4732484G22Rik) | |
Results | Reference |
2* | J:119780 Bazzi H, Fantauzzo KA, Richardson GD, Jahoda CA, Christiano AM, Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression. Dev Dyn. 2007 Mar 1;236(4):961-970 |
1 | J:321162 Boix J, Carceller E, Sevilla LM, Marcos-Garces V, Perez P, The mineralocorticoid receptor plays a transient role in mouse skin development. Exp Dermatol. 2016 Jan;25(1):69-71 |
1 | J:182938 Sevilla LM, Bayo P, Latorre V, Sanchis A, Perez P, Glucocorticoid receptor regulates overlapping and differential gene subsets in developing and adult skin. Mol Endocrinol. 2010 Nov;24(11):2166-78 |
Krt79 keratin 79 (Synonyms: MGC:36907) | |
Results | Reference |
1 | J:147576 Kunisada M, Cui CY, Piao Y, Ko MS, Schlessinger D, Requirement for Shh and Fox family genes at different stages in sweat gland development. Hum Mol Genet. 2009 May 15;18(10):1769-78 |
1 | J:341496 Veniaminova NA, Jia YY, Hartigan AM, Huyge TJ, Tsai SY, Grachtchouk M, Nakagawa S, Dlugosz AA, Atwood SX, Wong SY, Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury. Cell Rep. 2023 Sep 26;42(9):113121 |
1 | J:206321 Veniaminova NA, Vagnozzi AN, Kopinke D, Do TT, Murtaugh LC, Maillard I, Dlugosz AA, Reiter JF, Wong SY, Keratin 79 identifies a novel population of migratory epithelial cells that initiates hair canal morphogenesis and regeneration. Development. 2013 Dec;140(24):4870-80 |
Krt82 keratin 82 (Synonyms: Krt2-20) | |
Results | Reference |
1 | J:136961 Zhang Y, Andl T, Yang SH, Teta M, Liu F, Seykora JT, Tobias JW, Piccolo S, Schmidt-Ullrich R, Nagy A, Taketo MM, Dlugosz AA, Millar SE, Activation of {beta}-catenin signaling programs embryonic epidermis to hair follicle fate. Development. 2008 Jun;135(12):2161-72 |
Krt84 keratin 84 (Synonyms: HRb-1, Krt2-16, Krt2-3) | |
Results | Reference |
1* | J:94541 Jonker L, Kist R, Aw A, Wappler I, Peters H, Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium. Mech Dev. 2004 Nov;121(11):1313-22 |
Krt86 keratin 86 (Synonyms: Khb4, Krt2-10, Krt2-11, MHb4) | |
Results | Reference |
1* | J:198837 Cui CY, Klar J, Georgii-Heming P, Frojmark AS, Baig SM, Schlessinger D, Dahl N, Frizzled6 deficiency disrupts the differentiation process of nail development. J Invest Dermatol. 2013 Aug;133(8):1990-7 |
Krtap9-3 keratin associated protein 9-3 (Synonyms: 2310040M23Rik) | |
Results | Reference |
1* | J:94541 Jonker L, Kist R, Aw A, Wappler I, Peters H, Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium. Mech Dev. 2004 Nov;121(11):1313-22 |
Krtap13 keratin associated protein 13 (Synonyms: 4C32) | |
Results | Reference |
2 | J:192725 Okano J, Lichti U, Mamiya S, Aronova M, Zhang G, Yuspa SH, Hamada H, Sakai Y, Morasso MI, Increased retinoic acid levels through ablation of Cyp26b1 determine the processes of embryonic skin barrier formation and peridermal development. J Cell Sci. 2012 Apr 1;125(Pt 7):1827-36 |
3* | J:48444 Takaishi M, Takata Y, Kuroki T, Huh N, Isolation and characterization of a putative keratin-associated protein gene expressed in embryonic skin of mice. J Invest Dermatol. 1998 Jul;111(1):128-32 |
Krtap13-20 keratin associated protein 13-20 (Synonyms: 2310034C09Rik) | |
Results | Reference |
1* | J:129949 Cui CY, Kunisada M, Esibizione D, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet. 2007 Nov 1;16(21):2583-90 |
1 | J:192725 Okano J, Lichti U, Mamiya S, Aronova M, Zhang G, Yuspa SH, Hamada H, Sakai Y, Morasso MI, Increased retinoic acid levels through ablation of Cyp26b1 determine the processes of embryonic skin barrier formation and peridermal development. J Cell Sci. 2012 Apr 1;125(Pt 7):1827-36 |
Krtap13-21 keratin associated protein 13-21 (Synonyms: 2310057N15Rik) | |
Results | Reference |
1* | J:129949 Cui CY, Kunisada M, Esibizione D, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet. 2007 Nov 1;16(21):2583-90 |
1 | J:192725 Okano J, Lichti U, Mamiya S, Aronova M, Zhang G, Yuspa SH, Hamada H, Sakai Y, Morasso MI, Increased retinoic acid levels through ablation of Cyp26b1 determine the processes of embryonic skin barrier formation and peridermal development. J Cell Sci. 2012 Apr 1;125(Pt 7):1827-36 |
Krtcap2 keratinocyte associated protein 2 (Synonyms: 0610010I12Rik) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
Krtdap keratinocyte differentiation associated protein (Synonyms: Kdap, sk221) | |
Results | Reference |
1* | J:119780 Bazzi H, Fantauzzo KA, Richardson GD, Jahoda CA, Christiano AM, Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression. Dev Dyn. 2007 Mar 1;236(4):961-970 |
L1cam L1 cell adhesion molecule (Synonyms: CD171, L1, L1-NCAM, NCAM-L1) | |
Results | Reference |
1 | J:225119 Aida T, Ito Y, Takahashi YK, Tanaka K, Overstimulation of NMDA receptors impairs early brain development in vivo. PLoS One. 2012;7(5):e36853 |
1 | J:195145 Amaniti EM, Hasenpusch-Theil K, Li Z, Magnani D, Kessaris N, Mason JO, Theil T, Gli3 is required in Emx1(+) progenitors for the development of the corpus callosum. Dev Biol. 2013 Apr 15;376(2):113-24 |
1 | J:272349 Baba K, Yoshida W, Toriyama M, Shimada T, Manning CF, Saito M, Kohno K, Trimmer JS, Watanabe R, Inagaki N, Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance. Elife. 2018 Aug 7;7:e34593 |
1 | J:183848 Benadiba C, Magnani D, Niquille M, Morle L, Valloton D, Nawabi H, Ait-Lounis A, Otsmane B, Reith W, Theil T, Hornung JP, Lebrand C, Durand B, The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development. PLoS Genet. 2012 Mar;8(3):e1002606 |
1* | J:60855 Birgbauer E, Cowan CA, Sretavan DW, Henkemeyer M, Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina. Development. 2000 Mar;127(6):1231-41 |
1 | J:295421 Brosig A, Fuchs J, Ipek F, Kroon C, Schrotter S, Vadhvani M, Polyzou A, Ledderose J, van Diepen M, Holzhutter HG, Trimbuch T, Gimber N, Schmoranzer J, Lieberam I, Rosenmund C, Spahn C, Scheerer P, Szczepek M, Leondaritis G, Eickholt BJ, The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches. Cell Rep. 2019 Nov 12;29(7):2028-2040.e8 |
1 | J:68904 Brouns MR, Matheson SF, Settleman J, p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation. Nat Cell Biol. 2001 Apr;3(4):361-7 |
1 | J:311855 Brudvig JJ, Cain JT, Schmidt-Grimminger GG, Stumpo DJ, Roux KJ, Blackshear PJ, Weimer JM, MARCKS Is Necessary for Netrin-DCC Signaling and Corpus Callosum Formation. Mol Neurobiol. 2018 Nov;55(11):8388-8402 |
1* | J:150043 Bush JO, Soriano P, Ephrin-B1 regulates axon guidance by reverse signaling through a PDZ-dependent mechanism. Genes Dev. 2009 Jul 1;23(13):1586-99 |
1 | J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5 |
1 | J:184158 Chenaux G, Henkemeyer M, Forward signaling by EphB1/EphB2 interacting with ephrin-B ligands at the optic chiasm is required to form the ipsilateral projection. Eur J Neurosci. 2011 Nov;34(10):1620-33 |
1* | J:71338 Chung WW, Lagenaur CF, Yan YM, Lund JS, Developmental expression of neural cell adhesion molecules in the mouse neocortex and olfactory bulb. J Comp Neurol. 1991 Dec 8;314(2):290-305 |
1 | J:226607 Clegg JM, Li Z, Molinek M, Caballero IM, Manuel MN, Price DJ, Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons. Neural Dev. 2015;10(1):26 |
1 | J:248927 Clements R, Turk R, Campbell KP, Wright KM, Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development. J Neurosci. 2017 Aug 30;37(35):8559-8574 |
1 | J:264980 Coffinier C, Jung HJ, Nobumori C, Chang S, Tu Y, Barnes RH 2nd, Yoshinaga Y, de Jong PJ, Vergnes L, Reue K, Fong LG, Young SG, Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell. 2011 Dec;22(23):4683-93 |
1 | J:313341 Comer JD, Pan FC, Willet SG, Haldipur P, Millen KJ, Wright CV, Kaltschmidt JA, Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3. Front Neural Circuits. 2015;9:36 |
1 | J:197849 Deck M, Lokmane L, Chauvet S, Mailhes C, Keita M, Niquille M, Yoshida M, Yoshida Y, Lebrand C, Mann F, Grove EA, Garel S, Pathfinding of corticothalamic axons relies on a rendezvous with thalamic projections. Neuron. 2013 Feb 6;77(3):472-84 |
1* | J:274718 Diao Y, Cui L, Chen Y, Burbridge TJ, Han W, Wirth B, Sestan N, Crair MC, Zhang J, Reciprocal Connections Between Cortex and Thalamus Contribute to Retinal Axon Targeting to Dorsal Lateral Geniculate Nucleus. Cereb Cortex. 2018 Apr 1;28(4):1168-1182 |
1 | J:306056 Doyle DZ, Lam MM, Qalieh A, Qalieh Y, Sorel A, Funk OH, Kwan KY, Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity. Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2100686118 |
1 | J:168258 Dwyer ND, Manning DK, Moran JL, Mudbhary R, Fleming MS, Favero CB, Vock VM, O'Leary DD, Walsh CA, Beier DR, A forward genetic screen with a thalamocortical axon reporter mouse yields novel neurodevelopment mutants and a distinct emx2 mutant phenotype. Neural Dev. 2011;6:3 |
1 | J:311814 Eom TY, Stanco A, Guo J, Wilkins G, Deslauriers D, Yan J, Monckton C, Blair J, Oon E, Perez A, Salas E, Oh A, Ghukasyan V, Snider WD, Rubenstein JL, Anton ES, Differential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration. Dev Cell. 2014 Dec 22;31(6):677-89 |
1 | J:172287 Esteve P, Sandonis A, Cardozo M, Malapeira J, Ibanez C, Crespo I, Marcos S, Gonzalez-Garcia S, Toribio ML, Arribas J, Shimono A, Guerrero I, Bovolenta P, SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis. Nat Neurosci. 2011 May;14(5):562-9 |
1 | J:157201 Eto K, Kawauchi T, Osawa M, Tabata H, Nakajima K, Role of dual leucine zipper-bearing kinase (DLK/MUK/ZPK) in axonal growth. Neurosci Res. 2010 Jan;66(1):37-45 |
1 | J:119469 Fouquet C, Di Meglio T, Ma L, Kawasaki T, Long H, Hirata T, Tessier-Lavigne M, Chedotal A, Nguyen-Ba-Charvet KT, Robo1 and robo2 control the development of the lateral olfactory tract. J Neurosci. 2007 Mar 14;27(11):3037-45 |
1* | J:19818 Franz T, Extra-toes (Xt) homozygous mutant mice demonstrate a role for the Gli-3 gene in the development of the forebrain. Acta Anat (Basel). 1994;150(1):38-44 |
1 | J:215584 Gil-Sanz C, Landeira B, Ramos C, Costa MR, Muller U, Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon. J Neurosci. 2014 Aug 6;34(32):10475-87 |
1 | J:105160 Guenette S, Chang Y, Hiesberger T, Richardson JA, Eckman CB, Eckman EA, Hammer RE, Herz J, Essential roles for the FE65 amyloid precursor protein-interacting proteins in brain development. EMBO J. 2006 Jan 25;25(2):420-31 |
1 | J:229411 Hakanen J, Salminen M, Defects in neural guidepost structures and failure to remove leptomeningeal cells from the septal midline behind the interhemispheric fusion defects in Netrin1 deficient mice. Int J Dev Neurosci. 2015 Dec;47(Pt B):206-15 |
1* | J:91247 Hirata T, Suda Y, Nakao K, Narimatsu M, Hirano T, Hibi M, Zinc finger gene fez-like functions in the formation of subplate neurons and thalamocortical axons. Dev Dyn. 2004 Jul;230(3):546-56 |
1 | J:94593 Inaki K, Nishimura S, Nakashiba T, Itohara S, Yoshihara Y, Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules. J Comp Neurol. 2004 Nov 15;479(3):243-56 |
1 | J:249035 Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M, McGillewie L, Bar S, Minocha S, Chevalier C, Po C, Chelly J, Mandel JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, Herault Y, Collins SC, Friant S, Godin JD, Yalcin B, WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9308-E9317 |
1 | J:221642 Klingler E, Martin PM, Garcia M, Moreau-Fauvarque C, Falk J, Chareyre F, Giovannini M, Chedotal A, Girault JA, Goutebroze L, The cytoskeleton-associated protein SCHIP1 is involved in axon guidance, and is required for piriform cortex and anterior commissure development. Development. 2015 Jun 1;142(11):2026-36 |
1* | J:99710 Kudo C, Ajioka I, Hirata Y, Nakajima K, Expression profiles of EphA3 at both the RNA and protein level in the developing mammalian forebrain. J Comp Neurol. 2005 Jul 4;487(3):255-69 |
1 | J:217604 Lavado A, Ware M, Pare J, Cao X, The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Development. 2014 Nov;141(21):4182-93 |
1* | J:96395 Lee S, Walker CL, Karten B, Kuny SL, Tennese AA, O'Neill MA, Wevrick R, Essential role for the Prader-Willi syndrome protein necdin in axonal outgrowth. Hum Mol Genet. 2005 Mar 1;14(5):627-37 |
1 | J:325446 Lepiemme F, Stoufflet J, Javier-Torrent M, Mazzucchelli G, Silva CG, Nguyen L, Oligodendrocyte precursors guide interneuron migration by unidirectional contact repulsion. Science. 2022 May 20;376(6595):eabn6204 |
1* | J:104312 Li HP, Oohira A, Ogawa M, Kawamura K, Kawano H, Aberrant trajectory of thalamocortical axons associated with abnormal localization of neurocan immunoreactivity in the cerebral neocortex of reeler mutant mice. Eur J Neurosci. 2005 Dec;22(11):2689-96 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1* | J:69842 Lustig M, Erskine L, Mason CA, Grumet M, Sakurai T, Nr-CAM expression in the developing mouse nervous system: ventral midline structures, specific fiber tracts, and neuropilar regions. J Comp Neurol. 2001 May 21;434(1):13-28 |
1 | J:217046 Magnani D, Hasenpusch-Theil K, Benadiba C, Yu T, Basson MA, Price DJ, Lebrand C, Theil T, Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Cereb Cortex. 2014 Jan;24(1):186-98 |
2 | J:137605 Manuel M, Pratt T, Liu M, Jeffery G, Price DJ, Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance. BMC Dev Biol. 2008;8:59 |
1 | J:220152 Marcos S, Nieto-Lopez F, Sandonis A, Cardozo MJ, Di Marco F, Esteve P, Bovolenta P, Secreted frizzled related proteins modulate pathfinding and fasciculation of mouse retina ganglion cell axons by direct and indirect mechanisms. J Neurosci. 2015 Mar 18;35(11):4729-40 |
1 | J:348685 Masuda A, Nishida K, Ajima R, Saga Y, Bakhtan M, Klar A, Hirata T, Zhu Y, A global gene regulatory program and its region-specific regulator partition neurons into commissural and ipsilateral projection types. Sci Adv. 2024 May 24;10(21):eadk2149 |
1* | J:236412 Mestres I, Chuang JZ, Calegari F, Conde C, Sung CH, SARA regulates neuronal migration during neocortical development through L1 trafficking. Development. 2016 Sep 1;143(17):3143-53 |
1 | J:238369 Mihalas AB, Elsen GE, Bedogni F, Daza RA, Ramos-Laguna KA, Arnold SJ, Hevner RF, Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity. Cell Rep. 2016 Jun 28;16(1):92-105 |
1 | J:310398 Mire E, Hocine M, Bazellieres E, Jungas T, Davy A, Chauvet S, Mann F, Developmental Upregulation of Ephrin-B1 Silences Sema3C/Neuropilin-1 Signaling during Post-crossing Navigation of Corpus Callosum Axons. Curr Biol. 2018 Jun 4;28(11):1768-1782.e4 |
1* | J:74494 Nakashiba T, Nishimura S, Ikeda T, Itohara S, Complementary expression and neurite outgrowth activity of netrin-G subfamily members. Mech Dev. 2002 Feb;111(1-2):47-60 |
1 | J:290851 Quintana-Urzainqui I, Hernandez-Malmierca P, Clegg JM, Li Z, Kozic Z, Price DJ, The role of the diencephalon in the guidance of thalamocortical axons in mice. Development. 2020 Jun 26;147(12):dev184523 |
1 | J:234107 Saito Y, Miranda-Rottmann S, Ruggiu M, Park CY, Fak JJ, Zhong R, Duncan JS, Fabella BA, Junge HJ, Chen Z, Araya R, Fritzsch B, Hudspeth AJ, Darnell RB, NOVA2-mediated RNA regulation is required for axonal pathfinding during development. Elife. 2016;5:e14371 |
1* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
1 | J:110263 Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM, Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat Neurosci. 2006 Jun;9(6):787-97 |
1 | J:226502 Takagi T, Nishizaki Y, Matsui F, Wakamatsu N, Higashi Y, De novo inbred heterozygous Zeb2/Sip1 mutant mice uniquely generated by germ-line conditional knockout exhibit craniofacial, callosal and behavioral defects associated with Mowat-Wilson syndrome. Hum Mol Genet. 2015 Nov 15;24(22):6390-402 |
1 | J:221658 Vithayathil J, Pucilowska J, Goodnough LH, Atit RP, Landreth GE, Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation. J Neurosci. 2015 Apr 29;35(17):6836-48 |
1* | J:143543 Vogel T, Gruss P, Expression of Leukaemia associated transcription factor Af9/Mllt3 in the cerebral cortex of the mouse. Gene Expr Patterns. 2009 Feb;9(2):83-93 |
1 | J:171771 Wu CS, Zhu J, Wager-Miller J, Wang S, O'Leary D, Monory K, Lutz B, Mackie K, Lu HC, Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. Eur J Neurosci. 2010 Sep;32(5):693-706 |
1 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
L3mbtl3 L3MBTL3 histone methyl-lysine binding protein (Synonyms: MBT-1, mKIAA1798) | |
Results | Reference |
1 | J:346895 Guo P, Lim RC, Rajawasam K, Trinh T, Sun H, Zhang H, A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis. Elife. 2024 Feb 12;13 |
Lactb lactamase, beta (Synonyms: Mrpl56) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Lama1 laminin, alpha 1 (Synonyms: Lama) | |
Results | Reference |
1 | J:306061 Damen M, Wirtz L, Soroka E, Khatif H, Kukat C, Simons BD, Bazzi H, High proliferation and delamination during skin epidermal stratification. Nat Commun. 2021 May 28;12(1):3227 |
2 | J:346123 Darrigrand JF, Salowka A, Torres-Cano A, Tapia-Rojo R, Zhu T, Garcia-Manyes S, Spagnoli FM, Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner. Dev Cell. 2024 Feb 5;59(3):326-338.e5 |
1 | J:79739 Georges-Labouesse E, Mark M, Messaddeq N, Gansmuller A, Essential role of alpha 6 integrins in cortical and retinal lamination. Curr Biol. 1998 Aug 27;8(17):983-6 |
1 | J:294193 Jones LK, Lam R, McKee KK, Aleksandrova M, Dowling J, Alexander SI, Mallawaarachchi A, Cottle DL, Short KM, Pais L, Miner JH, Mallett AJ, Simons C, McCarthy H, Yurchenco PD, Smyth IM, A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder. Development. 2020 Jun 22;147(21):dev189183 |
1 | J:241849 Ma S, Santhosh D, Kumar T P, Huang Z, A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis. Dev Cell. 2017 May 22;41(4):366-381.e4 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:341276 Matrongolo MJ, Ho-Nguyen KT, Jain M, Ang PS, Reddy A, Schaper S, Tischfield MA, Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice. Development. 2023 Sep 15;150(18):dev201381 |
1* | J:59925 Miner JH, Li C, Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane. Dev Biol. 2000 Jan 15;217(2):278-89 |
1 | J:91048 Miner JH, Li C, Mudd JL, Go G, Sutherland AE, Compositional and structural requirements for laminin and basement membranes during mouse embryo implantation and gastrulation. Development. 2004 May;131(10):2247-56 |
1 | J:77264 Nguyen NM, Miner JH, Pierce RA, Senior RM, Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung. Dev Biol. 2002 Jun 15;246(2):231-44 |
1 | J:63385 Park K, Lee YD, Park HJ, Chun YM, Epithelial differentiation in developing murine eustachian tube and middle ear. Otolaryngol Head Neck Surg. 2000 Jun;122(6):902-7 |
1* | J:137581 Ratcliffe EM, D'Autreaux F, Gershon MD, Laminin terminates the Netrin/DCC mediated attraction of vagal sensory axons. Dev Neurobiol. 2008 Jun;68(7):960-71 |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
1* | J:3920 Schuger L, Varani J, Killen PD, Skubitz AP, Gilbride K, Laminin expression in the mouse lung increases with development and stimulates spontaneous organotypic rearrangement of mixed lung cells. Dev Dyn. 1992 Sep;195(1):43-54 |
2 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
2 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:361964 Wang M, Liu H, Zhang M, Niu X, Sun M, Wang F, Ni Y, Hong T, Zhang W, Dang S, The secreted protease ADAMTS18 links early isoform transformation and maturation of glomerular basement membrane macromolecules to the integrity of the glomerular filtration barrier. Biochem Biophys Res Commun. 2025 Mar 1;750:151386 |
1* | J:33225 Wu JE, Santoro SA, Differential expression of integrin alpha subunits supports distinct roles during lung branching morphogenesis. Dev Dyn. 1996 Jun;206(2):169-81 |
Lama2 laminin, alpha 2 (Synonyms: mer, merosin, nmf417) | |
Results | Reference |
1 | J:79739 Georges-Labouesse E, Mark M, Messaddeq N, Gansmuller A, Essential role of alpha 6 integrins in cortical and retinal lamination. Curr Biol. 1998 Aug 27;8(17):983-6 |
2 | J:55579 Lefebvre O, Sorokin L, Kedinger M, Simon-Assmann P, Developmental expression and cellular origin of the laminin alpha2, alpha4, and alpha5 chains in the intestine. Dev Biol. 1999 Jun 1;210(1):135-50 |
1 | J:333369 Lipp SN, Jacobson KR, Colling HA, Tuttle TG, Miles DT, McCreery KP, Calve S, Mechanical loading is required for initiation of extracellular matrix deposition at the developing murine myotendinous junction. Matrix Biol. 2023 Feb;116:28-48 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1* | J:59925 Miner JH, Li C, Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane. Dev Biol. 2000 Jan 15;217(2):278-89 |
1 | J:77264 Nguyen NM, Miner JH, Pierce RA, Senior RM, Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung. Dev Biol. 2002 Jun 15;246(2):231-44 |
1 | J:251718 Pietila I, Prunskaite-Hyyrylainen R, Kaisto S, Tika E, van Eerde AM, Salo AM, Garma L, Miinalainen I, Feitz WF, Bongers EM, Juffer A, Knoers NV, Renkema KY, Myllyharju J, Vainio SJ, Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning. PLoS One. 2016;11(1):e0147171 |
1 | J:44059 Salmivirta K, Sorokin LM, Ekblom P, Differential expression of laminin alpha chains during murine tooth development. Dev Dyn. 1997 Nov;210(3):206-15 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
Lama3 laminin, alpha 3 (Synonyms: [a]3B, nicein, 150kDa) | |
Results | Reference |
2* | J:38997 Aberdam D, Aguzzi A, Baudoin C, Galliano MF, Ortonne JP, Meneguzzi G, Developmental expression of nicein adhesion protein (laminin-5) subunits suggests multiple morphogenic roles. Cell Adhes Commun. 1994 Jun;2(2):115-29 |
2 | J:17618 Aberdam D, Galliano MF, Mattei MG, Pisani-Spadafora A, Ortonne JP, Meneguzzi G, Assignment of mouse nicein genes to chromosomes 1 and 18. Mamm Genome. 1994 Apr;5(4):229-33 |
3 | J:316440 Imanishi H, Tsuruta D, Tateishi C, Sugawara K, Kobayashi H, Ishii M, Kishi K, Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis. Med Mol Morphol. 2014 Mar;47(1):38-42 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:77264 Nguyen NM, Miner JH, Pierce RA, Senior RM, Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung. Dev Biol. 2002 Jun 15;246(2):231-44 |
1 | J:32722 Orian-Rousseau V, Aberdam D, Fontao L, Chevalier L, Meneguzzi G, Kedinger M, Simon-Assmann P, Developmental expression of laminin-5 and HD1 in the intestine: epithelial to mesenchymal shift for the laminin gamma-2 chain subunit deposition. Dev Dyn. 1996 May;206(1):12-23 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
2 | J:45691 Yoshiba K, Yoshiba N, Aberdam D, Meneguzzi G, Perrin-Schmitt F, Stoetzel C, Ruch JV, Lesot H, Expression and localization of laminin-5 subunits during mouse tooth development. Dev Dyn. 1998 Feb;211(2):164-76 |
Lama4 laminin, alpha 4 (Synonyms: laminin [a]4) | |
Results | Reference |
1* | J:84903 Bolcato-Bellemin AL, Lefebvre O, Arnold C, Sorokin L, Miner JH, Kedinger M, Simon-Assmann P, Laminin alpha5 chain is required for intestinal smooth muscle development. Dev Biol. 2003 Aug 15;260(2):376-90 |
1 | J:329963 Janardhan HP, Dresser K, Hutchinson L, Trivedi CM, Pathological MAPK activation-mediated lymphatic basement membrane disruption causes lymphangiectasia that is treatable with ravoxertinib. JCI Insight. 2022 Sep 8;7(17):e153033 |
3 | J:55579 Lefebvre O, Sorokin L, Kedinger M, Simon-Assmann P, Developmental expression and cellular origin of the laminin alpha2, alpha4, and alpha5 chains in the intestine. Dev Biol. 1999 Jun 1;210(1):135-50 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1* | J:59925 Miner JH, Li C, Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane. Dev Biol. 2000 Jan 15;217(2):278-89 |
1 | J:77264 Nguyen NM, Miner JH, Pierce RA, Senior RM, Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung. Dev Biol. 2002 Jun 15;246(2):231-44 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
Lama5 laminin, alpha 5 (Synonyms: mKIAA0533) | |
Results | Reference |
1* | J:84903 Bolcato-Bellemin AL, Lefebvre O, Arnold C, Sorokin L, Miner JH, Kedinger M, Simon-Assmann P, Laminin alpha5 chain is required for intestinal smooth muscle development. Dev Biol. 2003 Aug 15;260(2):376-90 |
1 | J:269938 Bovay E, Sabine A, Prat-Luri B, Kim S, Son K, Willrodt AH, Olsson C, Halin C, Kiefer F, Betsholtz C, Jeon NL, Luther SA, Petrova TV, Multiple roles of lymphatic vessels in peripheral lymph node development. J Exp Med. 2018 Nov 5;215(11):2760-2777 |
1 | J:166772 DeRouen MC, Zhen H, Tan SH, Williams S, Marinkovich MP, Oro AE, Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation. BMC Dev Biol. 2010;10:112 |
2 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
3 | J:316440 Imanishi H, Tsuruta D, Tateishi C, Sugawara K, Kobayashi H, Ishii M, Kishi K, Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis. Med Mol Morphol. 2014 Mar;47(1):38-42 |
1* | J:82378 Jamora C, DasGupta R, Kocieniewski P, Fuchs E, Links between signal transduction, transcription and adhesion in epithelial bud development. Nature. 2003 Mar 20;422(6929):317-22 |
1 | J:294193 Jones LK, Lam R, McKee KK, Aleksandrova M, Dowling J, Alexander SI, Mallawaarachchi A, Cottle DL, Short KM, Pais L, Miner JH, Mallett AJ, Simons C, McCarthy H, Yurchenco PD, Smyth IM, A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder. Development. 2020 Jun 22;147(21):dev189183 |
3 | J:55579 Lefebvre O, Sorokin L, Kedinger M, Simon-Assmann P, Developmental expression and cellular origin of the laminin alpha2, alpha4, and alpha5 chains in the intestine. Dev Biol. 1999 Jun 1;210(1):135-50 |
1 | J:321068 Maimets M, Pedersen MT, Guiu J, Dreier J, Thodberg M, Antoku Y, Schweiger PJ, Rib L, Bressan RB, Miao Y, Garcia KC, Sandelin A, Serup P, Jensen KB, Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling. Nat Commun. 2022 Feb 7;13(1):715 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1* | J:59925 Miner JH, Li C, Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane. Dev Biol. 2000 Jan 15;217(2):278-89 |
1 | J:71478 Moulson CL, Li C, Miner JH, Localization of Lutheran, a novel laminin receptor, in normal, knockout, and transgenic mice suggests an interaction with laminin alpha5 in vivo. Dev Dyn. 2001 Sep;222(1):101-14 |
1 | J:77264 Nguyen NM, Miner JH, Pierce RA, Senior RM, Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung. Dev Biol. 2002 Jun 15;246(2):231-44 |
2 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:361964 Wang M, Liu H, Zhang M, Niu X, Sun M, Wang F, Ni Y, Hong T, Zhang W, Dang S, The secreted protease ADAMTS18 links early isoform transformation and maturation of glomerular basement membrane macromolecules to the integrity of the glomerular filtration barrier. Biochem Biophys Res Commun. 2025 Mar 1;750:151386 |
Lamb1 laminin B1 (Synonyms: C80098, C81607, D130003D08Rik, Lamb-1) | |
Results | Reference |
1* | J:84903 Bolcato-Bellemin AL, Lefebvre O, Arnold C, Sorokin L, Miner JH, Kedinger M, Simon-Assmann P, Laminin alpha5 chain is required for intestinal smooth muscle development. Dev Biol. 2003 Aug 15;260(2):376-90 |
1 | J:191082 Clavel C, Grisanti L, Zemla R, Rezza A, Barros R, Sennett R, Mazloom AR, Chung CY, Cai X, Cai CL, Pevny L, Nicolis S, Ma'ayan A, Rendl M, Sox2 in the dermal papilla niche controls hair growth by fine-tuning BMP signaling in differentiating hair shaft progenitors. Dev Cell. 2012 Nov 13;23(5):981-94 |
1 | J:195895 Hanson KP, Jung JP, Tran QA, Hsu SP, Iida R, Ajeti V, Campagnola PJ, Eliceiri KW, Squirrell JM, Lyons GE, Ogle BM, Spatial and temporal analysis of extracellular matrix proteins in the developing murine heart: a blueprint for regeneration. Tissue Eng Part A. 2013 May;19(9-10):1132-43 |
1 | J:105090 Heimann P, Kuschel T, Jockusch H, Elimination by necrosis, not apoptosis, of embryonic extraocular muscles in the muscular dysgenesis mutant of the mouse. Cell Tissue Res. 2004 Feb;315(2):243-7 |
1 | J:316440 Imanishi H, Tsuruta D, Tateishi C, Sugawara K, Kobayashi H, Ishii M, Kishi K, Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis. Med Mol Morphol. 2014 Mar;47(1):38-42 |
1 | J:294193 Jones LK, Lam R, McKee KK, Aleksandrova M, Dowling J, Alexander SI, Mallawaarachchi A, Cottle DL, Short KM, Pais L, Miner JH, Mallett AJ, Simons C, McCarthy H, Yurchenco PD, Smyth IM, A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder. Development. 2020 Jun 22;147(21):dev189183 |
1 | J:321068 Maimets M, Pedersen MT, Guiu J, Dreier J, Thodberg M, Antoku Y, Schweiger PJ, Rib L, Bressan RB, Miao Y, Garcia KC, Sandelin A, Serup P, Jensen KB, Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling. Nat Commun. 2022 Feb 7;13(1):715 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1* | J:59925 Miner JH, Li C, Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane. Dev Biol. 2000 Jan 15;217(2):278-89 |
1 | J:251718 Pietila I, Prunskaite-Hyyrylainen R, Kaisto S, Tika E, van Eerde AM, Salo AM, Garma L, Miinalainen I, Feitz WF, Bongers EM, Juffer A, Knoers NV, Renkema KY, Myllyharju J, Vainio SJ, Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning. PLoS One. 2016;11(1):e0147171 |
1 | J:35512 Rothman TP, Chen J, Howard MJ, Costantini F, Schuchardt A, Pachnis V, Gershon MD, Increased expression of laminin-1 and collagen (IV) subunits in the aganglionic bowel of ls/ls, but not c-ret -/- mice. Dev Biol. 1996 Sep 15;178(2):498-513 |
1* | J:3920 Schuger L, Varani J, Killen PD, Skubitz AP, Gilbride K, Laminin expression in the mouse lung increases with development and stimulates spontaneous organotypic rearrangement of mixed lung cells. Dev Dyn. 1992 Sep;195(1):43-54 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:361964 Wang M, Liu H, Zhang M, Niu X, Sun M, Wang F, Ni Y, Hong T, Zhang W, Dang S, The secreted protease ADAMTS18 links early isoform transformation and maturation of glomerular basement membrane macromolecules to the integrity of the glomerular filtration barrier. Biochem Biophys Res Commun. 2025 Mar 1;750:151386 |
1* | J:33225 Wu JE, Santoro SA, Differential expression of integrin alpha subunits supports distinct roles during lung branching morphogenesis. Dev Dyn. 1996 Jun;206(2):169-81 |
Lamb2 laminin, beta 2 (Synonyms: Lamb-2, Lams, npht) | |
Results | Reference |
1* | J:38997 Aberdam D, Aguzzi A, Baudoin C, Galliano MF, Ortonne JP, Meneguzzi G, Developmental expression of nicein adhesion protein (laminin-5) subunits suggests multiple morphogenic roles. Cell Adhes Commun. 1994 Jun;2(2):115-29 |
1* | J:84903 Bolcato-Bellemin AL, Lefebvre O, Arnold C, Sorokin L, Miner JH, Kedinger M, Simon-Assmann P, Laminin alpha5 chain is required for intestinal smooth muscle development. Dev Biol. 2003 Aug 15;260(2):376-90 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:251718 Pietila I, Prunskaite-Hyyrylainen R, Kaisto S, Tika E, van Eerde AM, Salo AM, Garma L, Miinalainen I, Feitz WF, Bongers EM, Juffer A, Knoers NV, Renkema KY, Myllyharju J, Vainio SJ, Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning. PLoS One. 2016;11(1):e0147171 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:361964 Wang M, Liu H, Zhang M, Niu X, Sun M, Wang F, Ni Y, Hong T, Zhang W, Dang S, The secreted protease ADAMTS18 links early isoform transformation and maturation of glomerular basement membrane macromolecules to the integrity of the glomerular filtration barrier. Biochem Biophys Res Commun. 2025 Mar 1;750:151386 |
Lamb3 laminin, beta 3 (Synonyms: nicein, 125kDa) | |
Results | Reference |
2* | J:38997 Aberdam D, Aguzzi A, Baudoin C, Galliano MF, Ortonne JP, Meneguzzi G, Developmental expression of nicein adhesion protein (laminin-5) subunits suggests multiple morphogenic roles. Cell Adhes Commun. 1994 Jun;2(2):115-29 |
2 | J:17618 Aberdam D, Galliano MF, Mattei MG, Pisani-Spadafora A, Ortonne JP, Meneguzzi G, Assignment of mouse nicein genes to chromosomes 1 and 18. Mamm Genome. 1994 Apr;5(4):229-33 |
3 | J:316440 Imanishi H, Tsuruta D, Tateishi C, Sugawara K, Kobayashi H, Ishii M, Kishi K, Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis. Med Mol Morphol. 2014 Mar;47(1):38-42 |
1 | J:42382 Kuster JE, Guarnieri MH, Ault JG, Flaherty L, Swiatek PJ, IAP insertion in the murine LamB3 gene results in junctional epidermolysis bullosa. Mamm Genome. 1997 Sep;8(9):673-81 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
2 | J:45691 Yoshiba K, Yoshiba N, Aberdam D, Meneguzzi G, Perrin-Schmitt F, Stoetzel C, Ruch JV, Lesot H, Expression and localization of laminin-5 subunits during mouse tooth development. Dev Dyn. 1998 Feb;211(2):164-76 |
Lamc1 laminin, gamma 1 (Synonyms: Lamb2, laminin B2) | |
Results | Reference |
1* | J:84903 Bolcato-Bellemin AL, Lefebvre O, Arnold C, Sorokin L, Miner JH, Kedinger M, Simon-Assmann P, Laminin alpha5 chain is required for intestinal smooth muscle development. Dev Biol. 2003 Aug 15;260(2):376-90 |
1 | J:170886 Fujiwara H, Ferreira M, Donati G, Marciano DK, Linton JM, Sato Y, Hartner A, Sekiguchi K, Reichardt LF, Watt FM, The basement membrane of hair follicle stem cells is a muscle cell niche. Cell. 2011 Feb 18;144(4):577-89 |
1* | J:167409 Grimal S, Puech S, Wagener R, Venteo S, Carroll P, Fichard-Carroll A, Collagen XXVIII is a distinctive component of the peripheral nervous system nodes of ranvier and surrounds nonmyelinating glial cells. Glia. 2010 Dec;58(16):1977-87 |
1 | J:105090 Heimann P, Kuschel T, Jockusch H, Elimination by necrosis, not apoptosis, of embryonic extraocular muscles in the muscular dysgenesis mutant of the mouse. Cell Tissue Res. 2004 Feb;315(2):243-7 |
1 | J:316440 Imanishi H, Tsuruta D, Tateishi C, Sugawara K, Kobayashi H, Ishii M, Kishi K, Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis. Med Mol Morphol. 2014 Mar;47(1):38-42 |
1 | J:294193 Jones LK, Lam R, McKee KK, Aleksandrova M, Dowling J, Alexander SI, Mallawaarachchi A, Cottle DL, Short KM, Pais L, Miner JH, Mallett AJ, Simons C, McCarthy H, Yurchenco PD, Smyth IM, A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder. Development. 2020 Jun 22;147(21):dev189183 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1* | J:59925 Miner JH, Li C, Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane. Dev Biol. 2000 Jan 15;217(2):278-89 |
1 | J:77264 Nguyen NM, Miner JH, Pierce RA, Senior RM, Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung. Dev Biol. 2002 Jun 15;246(2):231-44 |
1* | J:3920 Schuger L, Varani J, Killen PD, Skubitz AP, Gilbride K, Laminin expression in the mouse lung increases with development and stimulates spontaneous organotypic rearrangement of mixed lung cells. Dev Dyn. 1992 Sep;195(1):43-54 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:361964 Wang M, Liu H, Zhang M, Niu X, Sun M, Wang F, Ni Y, Hong T, Zhang W, Dang S, The secreted protease ADAMTS18 links early isoform transformation and maturation of glomerular basement membrane macromolecules to the integrity of the glomerular filtration barrier. Biochem Biophys Res Commun. 2025 Mar 1;750:151386 |
1* | J:33225 Wu JE, Santoro SA, Differential expression of integrin alpha subunits supports distinct roles during lung branching morphogenesis. Dev Dyn. 1996 Jun;206(2):169-81 |
Lamc2 laminin, gamma 2 (Synonyms: nicein, 100kDa) | |
Results | Reference |
2* | J:38997 Aberdam D, Aguzzi A, Baudoin C, Galliano MF, Ortonne JP, Meneguzzi G, Developmental expression of nicein adhesion protein (laminin-5) subunits suggests multiple morphogenic roles. Cell Adhes Commun. 1994 Jun;2(2):115-29 |
2 | J:17618 Aberdam D, Galliano MF, Mattei MG, Pisani-Spadafora A, Ortonne JP, Meneguzzi G, Assignment of mouse nicein genes to chromosomes 1 and 18. Mamm Genome. 1994 Apr;5(4):229-33 |
1* | J:84903 Bolcato-Bellemin AL, Lefebvre O, Arnold C, Sorokin L, Miner JH, Kedinger M, Simon-Assmann P, Laminin alpha5 chain is required for intestinal smooth muscle development. Dev Biol. 2003 Aug 15;260(2):376-90 |
3 | J:316440 Imanishi H, Tsuruta D, Tateishi C, Sugawara K, Kobayashi H, Ishii M, Kishi K, Spatial and temporal control of laminin-332 and -511 expressions during hair morphogenesis. Med Mol Morphol. 2014 Mar;47(1):38-42 |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:251718 Pietila I, Prunskaite-Hyyrylainen R, Kaisto S, Tika E, van Eerde AM, Salo AM, Garma L, Miinalainen I, Feitz WF, Bongers EM, Juffer A, Knoers NV, Renkema KY, Myllyharju J, Vainio SJ, Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning. PLoS One. 2016;11(1):e0147171 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
2 | J:45691 Yoshiba K, Yoshiba N, Aberdam D, Meneguzzi G, Perrin-Schmitt F, Stoetzel C, Ruch JV, Lesot H, Expression and localization of laminin-5 subunits during mouse tooth development. Dev Dyn. 1998 Feb;211(2):164-76 |
Lamc3 laminin gamma 3 | |
Results | Reference |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:251718 Pietila I, Prunskaite-Hyyrylainen R, Kaisto S, Tika E, van Eerde AM, Salo AM, Garma L, Miinalainen I, Feitz WF, Bongers EM, Juffer A, Knoers NV, Renkema KY, Myllyharju J, Vainio SJ, Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning. PLoS One. 2016;11(1):e0147171 |
Lamp1 lysosomal-associated membrane protein 1 (Synonyms: CD107a, Lamp-1, Perk) | |
Results | Reference |
1 | J:355215 Kim J, Yu YS, Choi Y, Lee DH, Han S, Kwon J, Noda T, Ikawa M, Kim D, Kim H, Ballabio A, Kim KI, Baek SH, USF2 and TFEB compete in regulating lysosomal and autophagy genes. Nat Commun. 2024 Sep 27;15(1):8334 |
1 | J:363160 Yuizumi N, Harada Y, Kuniya T, Sunabori T, Koike M, Wakabayashi M, Ishihama Y, Suzuki Y, Kawaguchi D, Gotoh Y, Maintenance of neural stem-progenitor cells by the lysosomal biosynthesis regulators TFEB and TFE3 in the embryonic mouse telencephalon. Stem Cells. 2021 Jul;39(7):929-944 |
Lamp3 lysosomal-associated membrane protein 3 (Synonyms: 1200002D17Rik, Cd208, DC-LAMP, TSC403) | |
Results | Reference |
1 | J:202949 Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J, Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18042-51 |
2 | J:237343 Laresgoiti U, Nikolic MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL, Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016 Oct 15;143(20):3686-3699 |
Lars2 leucyl-tRNA synthetase, mitochondrial | |
Results | Reference |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
Lasp1 LIM and SH3 protein 1 (Synonyms: Def-4, SH3P6) | |
Results | Reference |
1 | J:208050 Huang TN, Chuang HC, Chou WH, Chen CY, Wang HF, Chou SJ, Hsueh YP, Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality. Nat Neurosci. 2014 Feb;17(2):240-7 |
1* | J:46102 Schreiber V, Masson R, Linares JL, Mattei MG, Tomasetto C, Rio MC, Chromosomal assignment and expression pattern of the murine Lasp-1 gene. Gene. 1998 Jan 30;207(2):171-5 |
Lats1 large tumor suppressor | |
Results | Reference |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
1 | J:309380 Mei L, Qv M, Bao H, He Q, Xu Y, Zhang Q, Shi W, Ren Q, Yan Z, Xu C, Tang C, Hussain M, Zeng LH, Wu X, SUMOylation activates large tumour suppressor 1 to maintain the tissue homeostasis during Hippo signalling. Oncogene. 2021 Sep;40(35):5357-5366 |
Lats2 large tumor suppressor 2 | |
Results | Reference |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
Lbhd2 LBH domain containing 2 (Synonyms: A230065H16Rik, Lbh2, LOC380787) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Lbr lamin B receptor | |
Results | Reference |
1* | J:138854 Cohen TV, Klarmann KD, Sakchaisri K, Cooper JP, Kuhns D, Anver M, Johnson PF, Williams SC, Keller JR, Stewart CL, The lamin B receptor under transcriptional control of C/EBPepsilon is required for morphological but not functional maturation of neutrophils. Hum Mol Genet. 2008 Oct 1;17(19):2921-33 |
Lbx1 ladybird homeobox 1 (Synonyms: Lbx1h) | |
Results | Reference |
1 | J:76658 Gross MK, Dottori M, Goulding M, Lbx1 specifies somatosensory association interneurons in the dorsal spinal cord. Neuron. 2002 May 16;34(4):535-49 |
1 | J:188329 Huang WH, Tupal S, Huang TW, Ward CS, Neul JL, Klisch TJ, Gray PA, Zoghbi HY, Atoh1 Governs the Migration of Postmitotic Neurons that Shape Respiratory Effectiveness at Birth and Chemoresponsiveness in Adulthood. Neuron. 2012 Sep 6;75(5):799-809 |
2* | J:29933 Jagla K, Dolle P, Mattei MG, Jagla T, Schuhbaur B, Dretzen G, Bellard F, Bellard M, Mouse Lbx1 and human LBX1 define a novel mammalian homeobox gene family related to the Drosophila lady bird genes. Mech Dev. 1995 Nov;53(3):345-56 |
1 | J:184011 John A, Brylka H, Wiegreffe C, Simon R, Liu P, Juttner R, Crenshaw EB 3rd, Luyten FP, Jenkins NA, Copeland NG, Birchmeier C, Britsch S, Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. Development. 2012 May;139(10):1831-41 |
1 | J:201154 Meziane H, Fraulob V, Riet F, Krezel W, Selloum M, Geffarth M, Acampora D, Herault Y, Simeone A, Brand M, Dolle P, Rhinn M, The homeodomain factor Gbx1 is required for locomotion and cell specification in the dorsal spinal cord. PeerJ. 2013;1:e142 |
1 | J:165741 Rojas A, Schachterle W, Xu SM, Martin F, Black BL, Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer. Dev Biol. 2010 Oct 15;346(2):346-55 |
1 | J:155760 Rose MF, Ren J, Ahmad KA, Chao HT, Klisch TJ, Flora A, Greer JJ, Zoghbi HY, Math1 is essential for the development of hindbrain neurons critical for perinatal breathing. Neuron. 2009 Nov 12;64(3):341-54 |
1 | J:116148 Stolt CC, Schlierf A, Lommes P, Hillgartner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M, SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell. 2006 Nov;11(5):697-709 |
Lbx2 ladybird homeobox 2 (Synonyms: Lbx2h) | |
Results | Reference |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
Lce1b late cornified envelope 1B (Synonyms: 1110029C13Rik, Sprrl5) | |
Results | Reference |
1 | J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39 |
Lce3b late cornified envelope 3B (Synonyms: 2310007F04Rik, Sprrl6A) | |
Results | Reference |
1 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
Lce3c late cornified envelope 3C (Synonyms: 2300007B01Rik, Eig3, Sprrl1) | |
Results | Reference |
1 | J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39 |
1* | J:94541 Jonker L, Kist R, Aw A, Wappler I, Peters H, Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium. Mech Dev. 2004 Nov;121(11):1313-22 |
Lck lymphocyte protein tyrosine kinase
(Synonyms:
Hck-3, p56 | |
Results | Reference |
1* | J:317552 Casey SC, Blumberg B, The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver. Mol Endocrinol. 2012 Jun;26(6):916-25 |
1* | J:55945 Wang JP, Chuang SM, Shen CL, Chen ST, Expression of Src family during development of the mouse nervous system. Biomed Res. 1998 OCT;19(5):315-325 |
Lcor ligand dependent nuclear receptor corepressor (Synonyms: 3110023F06Rik, A630025C20Rik, Gm340, LOC381224, mKIAA1795, Mlr2) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Lcp1 lymphocyte cytosolic protein 1 (Synonyms: D14Ertd310e, L-fimbrin, L-plastin, Pls2) | |
Results | Reference |
1* | J:26070 Chafel MM, Shen W, Matsudaira P, Sequential expression and differential localization of I-, L-, and T-fimbrin during differentiation of the mouse intestine and yolk sac. Dev Dyn. 1995 Jun;203(2):141-51 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Lct lactase (Synonyms: LOC226413, LPH, Lphl) | |
Results | Reference |
1 | J:122635 Bosse T, Fialkovich JJ, Piaseckyj CM, Beuling E, Broekman H, Grand RJ, Montgomery RK, Krasinski SD, Gata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during development. Am J Physiol Gastrointest Liver Physiol. 2007 May;292(5):G1302-14 |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
Ldb1 LIM domain binding 1 (Synonyms: CLIM2) | |
Results | Reference |
1 | J:237540 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R, The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development. 2016 Nov 15;143(22):4182-4192 |
1 | J:89175 Woodside KJ, Shen H, Muntzel C, Daller JA, Sommers CL, Love PE, Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes. Gene Expr Patterns. 2004 May;4(3):315-20 |
2 | J:280461 Xiao D, Jin K, Xiang M, Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development. Front Mol Neurosci. 2018;11:271 |
1 | J:129101 Xu X, Mannik J, Kudryavtseva E, Lin KK, Flanagan LA, Spencer J, Soto A, Wang N, Lu Z, Yu Z, Monuki ES, Andersen B, Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells. Dev Biol. 2007 Dec 15;312(2):484-500 |
Ldb2 LIM domain binding 2 (Synonyms: CLIM1, CLIM-1a, CLIM-1b, CLP-36, Ldb3) | |
Results | Reference |
1 | J:241102 Leone DP, Panagiotakos G, Heavner WE, Joshi P, Zhao Y, Westphal H, McConnell SK, Compensatory Actions of Ldb Adaptor Proteins During Corticospinal Motor Neuron Differentiation. Cereb Cortex. 2017 Feb 01;27(2):1686-1699 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
1 | J:129101 Xu X, Mannik J, Kudryavtseva E, Lin KK, Flanagan LA, Spencer J, Soto A, Wang N, Lu Z, Yu Z, Monuki ES, Andersen B, Co-factors of LIM domains (Clims/Ldb/Nli) regulate corneal homeostasis and maintenance of hair follicle stem cells. Dev Biol. 2007 Dec 15;312(2):484-500 |
Ldb3 LIM domain binding 3 (Synonyms: cypher, ZASP) | |
Results | Reference |
3* | J:82141 Huang C, Zhou Q, Liang P, Hollander MS, Sheikh F, Li X, Greaser M, Shelton GD, Evans S, Chen J, Characterization and in vivo functional analysis of splice variants of cypher. J Biol Chem. 2003 Feb 28;278(9):7360-5 |
Ldha lactate dehydrogenase A (Synonyms: l7R2, lactate dehydrogenase-A, Ldh-1, Ldh1, LDH-A) | |
Results | Reference |
1* | J:78912 Hellstrom M, Gerhardt H, Kalen M, Li X, Eriksson U, Wolburg H, Betsholtz C, Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol. 2001 Apr 30;153(3):543-53 |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
Ldhb lactate dehydrogenase B (Synonyms: H-Ldh, lactate dehydrogenase-B, Ldh-2) | |
Results | Reference |
1* | J:78912 Hellstrom M, Gerhardt H, Kalen M, Li X, Eriksson U, Wolburg H, Betsholtz C, Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol. 2001 Apr 30;153(3):543-53 |
Ldlr low density lipoprotein receptor | |
Results | Reference |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
1 | J:264124 Tsushima H, Tang YJ, Puviindran V, Hsu SC, Nadesan P, Yu C, Zhang H, Mirando AJ, Hilton MJ, Alman BA, Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis. Development. 2018 Jul 9;145(13):dev162396 |
Leat1 lncRNA Efnb2 associated transcript 1 (Synonyms: A630009H07Rik) | |
Results | Reference |
1* | J:284089 Mattiske D, Behringer RR, Overbeek PA, Pask AJ, A novel long non-coding RNA, Leat1, causes reduced anogenital distance and fertility in female mice. Differentiation. 2019 Dec 4;112:1-6 |
Lef1 lymphoid enhancer binding factor 1 (Synonyms: Lef-1, lymphoid enhancer factor 1) | |
Results | Reference |
1 | J:350005 Adasooriya D, Jeong JK, Kyeong M, Kan S, Kim J, Cho ES, Cho SW, Notum regulates the cusp and root patterns in mouse molar. Sci Rep. 2024 Jun 13;14(1):13633 |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
1 | J:127546 Brinkmeier ML, Potok MA, Davis SW, Camper SA, TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors. Dev Biol. 2007 Nov 15;311(2):396-407 |
2 | J:355647 Bugacov H, Der B, Briantseva BM, Guo Q, Kim S, Lindstrom NO, McMahon AP, Dose-dependent responses to canonical Wnt transcriptional complexes in the regulation of mammalian nephron progenitors. Development. 2024 Sep 15;151(18) |
1 | J:183485 Chen D, Jarrell A, Guo C, Lang R, Atit R, Dermal beta-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation. Development. 2012 Apr;139(8):1522-33 |
1* | J:248190 Chen K, Quan H, Chen G, Xiao D, Spatio-temporal expression patterns of Wnt signaling pathway during the development of temporomandibular condylar cartilage. Gene Expr Patterns. 2017 Nov;25-26:149-158 |
1 | J:196652 Choe Y, Kozlova A, Graf D, Pleasure SJ, Bone morphogenic protein signaling is a major determinant of dentate development. J Neurosci. 2013 Apr 17;33(16):6766-75 |
2 | J:206944 Clegg JM, Conway CD, Howe KM, Price DJ, Mason JO, Turnbull JE, Basson MA, Pratt T, Heparan sulfotransferases Hs6st1 and Hs2st Keep Erk in check for mouse corpus callosum development. J Neurosci. 2014 Feb 5;34(6):2389-401 |
2 | J:217500 Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D, Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60 |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:96446 Driskell RR, Liu X, Luo M, Filali M, Zhou W, Abbott D, Cheng N, Moothart C, Sigmund CD, Engelhardt JF, Wnt-responsive element controls Lef-1 promoter expression during submucosal gland morphogenesis. Am J Physiol Lung Cell Mol Physiol. 2004 Oct;287(4):L752-63 |
1 | J:194118 Fantauzzo KA, Kurban M, Levy B, Christiano AM, Trps1 and its target gene Sox9 regulate epithelial proliferation in the developing hair follicle and are associated with hypertrichosis. PLoS Genet. 2012;8(11):e1003002 |
2 | J:59284 Galceran J, Miyashita-Lin EM, Devaney E, Rubenstein JL, Grosschedl R, Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1. Development. 2000 Feb;127(3):469-82 |
2 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:356109 Ge W, Tan SJ, Wang SH, Li L, Sun XF, Shen W, Wang X, Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development. Theranostics. 2020;10(17):7581-7598 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1 | J:98430 Glass DA 2nd, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G, Canonical wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell. 2005 May;8(5):751-64 |
1 | J:189063 Goodnough LH, Chang AT, Treloar C, Yang J, Scacheri PC, Atit RP, Twist1 mediates repression of chondrogenesis by beta-catenin to promote cranial bone progenitor specification. Development. 2012 Dec;139(23):4428-38 |
1 | J:222425 Harada M, Omori A, Nakahara C, Nakagata N, Akita K, Yamada G, Tissue-specific roles of FGF signaling in external genitalia development. Dev Dyn. 2015 Jun;244(6):759-73 |
1 | J:119729 Iwatsuki K, Liu HX, Gronder A, Singer MA, Lane TF, Grosschedl R, Mistretta CM, Margolskee RF, Wnt signaling interacts with Shh to regulate taste papilla development. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2253-8 |
1 | J:324237 Kajimoto M, Suzuki K, Ueda Y, Fujimoto K, Takeo T, Nakagata N, Hyuga T, Isono K, Yamada G, Androgen/Wnt/beta-catenin signal axis augments cell proliferation of the mouse erectile tissue, corpus cavernosum. Congenit Anom (Kyoto). 2022 May;62(3):123-133 |
1 | J:51084 Keranen SV, Aberg T, Kettunen P, Thesleff I, Jernvall J, Association of developmental regulatory genes with the development of different molar tooth shapes in two species of rodents. Dev Genes Evol. 1998 Nov;208(9):477-86 |
1 | J:166777 Lavado A, Lagutin OV, Chow LM, Baker SJ, Oliver G, Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. PLoS Biol. 2010;8(8) |
1 | J:306027 Li H, Kurtzeborn K, Kupari J, Gui Y, Siefker E, Lu B, Matlik K, Olfat S, Montano-Rodriguez AR, Huh SH, Costantini F, Andressoo JO, Kuure S, Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF. Development. 2021 May 15;148(10):dev197475 |
1 | J:178118 Li Q, Bian S, Hong J, Kawase-Koga Y, Zhu E, Zheng Y, Yang L, Sun T, Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development. PLoS One. 2011;6(10):e26000 |
1 | J:189074 Li ZJ, Nieuwenhuis E, Nien W, Zhang X, Zhang J, Puviindran V, Wainwright BJ, Kim PC, Hui CC, Kif7 regulates Gli2 through Sufu-dependent and -independent functions during skin development and tumorigenesis. Development. 2012 Nov;139(22):4152-61 |
1 | J:91230 Liu X, Driskell RR, Luo M, Abbott D, Filali M, Cheng N, Sigmund CD, Engelhardt JF, Characterization of Lef-1 Promoter Segments that Facilitate Inductive Developmental Expression in Skin. J Invest Dermatol. 2004 Aug;123(2):264-74 |
1 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
1 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
1 | J:197885 Nagalski A, Irimia M, Szewczyk L, Ferran JL, Misztal K, Kuznicki J, Wisniewska MB, Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain. Brain Struct Funct. 2013 Nov;218(6):1531-49 |
1 | J:171374 Osorio KM, Lilja KC, Tumbar T, Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol. 2011 Apr 4;193(1):235-50 |
1 | J:331057 Parichha A, Datta D, Suresh V, Chatterjee M, Holtzman MJ, Tole S, Dentate gyrus morphogenesis is regulated by beta-catenin function in hem-derived fimbrial glia. Development. 2022 Nov 1;149(21):dev200953 |
1 | J:320719 Parichha A, Suresh V, Chatterjee M, Kshirsagar A, Ben-Reuven L, Olender T, Taketo MM, Radosevic V, Bobic-Rasonja M, Trnski S, Holtzman MJ, Jovanov-Milosevic N, Reiner O, Tole S, Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate. Nat Commun. 2022 Feb 2;13(1):633 |
1* | J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20 |
1 | J:324528 Qu R, Gupta K, Dong D, Jiang Y, Landa B, Saez C, Strickland G, Levinsohn J, Weng PL, Taketo MM, Kluger Y, Myung P, Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients. Dev Cell. 2022 Apr 25;57(8):1053-1067.e5 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1 | J:266746 Rudkouskaya A, Welch I, Dagnino L, ILK modulates epithelial polarity and matrix formation in hair follicles. Mol Biol Cell. 2014 Mar;25(5):620-32 |
1* | J:96501 Sasaki T, Ito Y, Xu X, Han J, Bringas P Jr, Maeda T, Slavkin HC, Grosschedl R, Chai Y, LEF1 is a critical epithelial survival factor during tooth morphogenesis. Dev Biol. 2005 Feb 1;278(1):130-43 |
1 | J:345231 Satta JP, Lan Q, Taketo MM, Mikkola ML, Stabilization of Epithelial beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis. J Invest Dermatol. 2023 Dec 28; |
1 | J:142359 Seah C, Levy MA, Jiang Y, Mokhtarzada S, Higgs DR, Gibbons RJ, Berube NG, Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53. J Neurosci. 2008 Nov 19;28(47):12570-80 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:199438 Siegenthaler JA, Choe Y, Patterson KP, Hsieh I, Li D, Jaminet SC, Daneman R, Kume T, Huang EJ, Pleasure SJ, Foxc1 is required by pericytes during fetal brain angiogenesis. Biol Open. 2013 Jul 15;2(7):647-59 |
1 | J:237499 Sima J, Piao Y, Chen Y, Schlessinger D, Molecular dynamics of Dkk4 modulates Wnt action and regulates meibomian gland development. Development. 2016 Dec 15;143(24):4723-4735 |
1 | J:270947 Song Y, Boncompagni AC, Kim SS, Gochnauer HR, Zhang Y, Loots GG, Wu D, Li Y, Xu M, Millar SE, Regional Control of Hairless versus Hair-Bearing Skin by Dkk2. Cell Rep. 2018 Dec 11;25(11):2981-2991.e3 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1 | J:144194 Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72 |
1* | J:73304 Tebar M, Destree O, de Vree WJ, Ten Have-Opbroek AA, Expression of Tcf/Lef and sFrp and localization of beta-catenin in the developing mouse lung. Mech Dev. 2001 Dec;109(2):437-40 |
1 | J:202875 Tokonzaba E, Chen J, Cheng X, Den Z, Ganeshan R, Muller EJ, Koch PJ, Plakoglobin as a regulator of desmocollin gene expression. J Invest Dermatol. 2013 Dec;133(12):2732-40 |
1 | J:159209 Tornqvist G, Sandberg A, Hagglund AC, Carlsson L, Cyclic expression of lhx2 regulates hair formation. PLoS Genet. 2010;6(4):e1000904 |
1* | J:18378 van Genderen C, Okamura RM, Farinas I, Quo RG, Parslow TG, Bruhn L, Grosschedl R, Development of several organs that require inductive epithelial-mesenchymal interactions is impaired in LEF-1-deficient mice. Genes Dev. 1994 Nov 15;8(22):2691-703 |
1 | J:338452 Wang D, Li H, Chandel NS, Dou Y, Yi R, MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters. Nat Commun. 2023 Jul 21;14(1):4404 |
1 | J:306208 Wu J, Tian Y, Han L, Liu C, Sun T, Li L, Yu Y, Lamichhane B, D'Souza RN, Millar SE, Krumlauf R, Ornitz DM, Feng JQ, Klein O, Zhao H, Zhang F, Linhardt RJ, Wang X, FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling. BMC Biol. 2020 Jul 14;18(1):87 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
1 | J:341689 Zhang B, Zhao C, Shen W, Li W, Zheng Y, Kong X, Wang J, Wu X, Zeng T, Liu Y, Zhou Y, KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors. Nat Commun. 2023 Oct 14;14(1):6489 |
1* | J:105879 Zhang TJ, Hoffman BG, Ruiz de Algara T, Helgason CD, SAGE reveals expression of Wnt signalling pathway members during mouse prostate development. Gene Expr Patterns. 2006 Mar;6(3):310-24 |
1* | J:173972 Zhao H, Li S, Han D, Kaartinen V, Chai Y, Alk5-mediated transforming growth factor beta signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol. 2011 May;31(10):2079-89 |
1 | J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687 |
Lefty1 left right determination factor 1 (Synonyms: Ebaf, Lefty, lefty-1, Stra3) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:320172 Souquet B, Tourpin S, Messiaen S, Moison D, Habert R, Livera G, Nodal signaling regulates the entry into meiosis in fetal germ cells. Endocrinology. 2012 May;153(5):2466-73 |
Lefty2 left-right determination factor 2 (Synonyms: 6030463A22Rik, Ebaf, Leftb) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:320172 Souquet B, Tourpin S, Messiaen S, Moison D, Habert R, Livera G, Nodal signaling regulates the entry into meiosis in fetal germ cells. Endocrinology. 2012 May;153(5):2466-73 |
Lemd2 LEM domain containing 2 (Synonyms: Lem2, MGC:37253, NET25) | |
Results | Reference |
1 | J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088 |
Leng8 leukocyte receptor cluster (LRC) member 8 | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Lep leptin | |
Results | Reference |
2 | J:102703 Fujimoto N, Matsuo N, Sumiyoshi H, Yamaguchi K, Saikawa T, Yoshimatsu H, Yoshioka H, Adiponectin is expressed in the brown adipose tissue and surrounding immature tissues in mouse embryos. Biochim Biophys Acta. 2005 Oct 15;1731(1):1-12 |
3 | J:74085 Hoggard N, Hunter L, Lea RG, Trayhurn P, Mercer JG, Ontogeny of the expression of leptin and its receptor in the murine fetus and placenta. Br J Nutr. 2000 Mar;83(3):317-26 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
Lepr leptin receptor (Synonyms: Leprb, LEPROT, leptin receptor gene-related protein, Modb1, obese-like, obl, Obr, OB-RGRP) | |
Results | Reference |
1* | J:308824 de Guia RM, Hassing AS, Ma T, Plucinska K, Holst B, Gerhart-Hines Z, Emanuelli B, Treebak JT, Ablation of Nampt in AgRP neurons leads to neurodegeneration and impairs fasting- and ghrelin-mediated food intake. FASEB J. 2021 May;35(5):e21450 |
3 | J:74085 Hoggard N, Hunter L, Lea RG, Trayhurn P, Mercer JG, Ontogeny of the expression of leptin and its receptor in the murine fetus and placenta. Br J Nutr. 2000 Mar;83(3):317-26 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:327415 Jing J, Feng J, Yuan Y, Guo T, Lei J, Pei F, Ho TV, Chai Y, Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022 Aug 16;13(1):4803 |
2 | J:62930 Udagawa J, Hatta T, Naora H, Otani H, Expression of the long form of leptin receptor (Ob-Rb) mRNA in the brain of mouse embryos and newborn mice. Brain Res. 2000 Jun 23;868(2):251-8 |
Letmd1 LETM1 domain containing 1 (Synonyms: 1110019O13Rik, HCCR1, HCCR-2) | |
Results | Reference |
1 | J:337469 Park A, Kim KE, Park I, Lee SH, Park KY, Jung M, Li X, Sleiman MB, Lee SJ, Kim DS, Kim J, Lim DS, Woo EJ, Lee EW, Han BS, Oh KJ, Lee SC, Auwerx J, Mun JY, Rhee HW, Kim WK, Bae KH, Suh JM, Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice. Nat Commun. 2023 Jun 23;14(1):3746 |
Lfng LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (Synonyms: lunatic fringe) | |
Results | Reference |
1 | J:63320 Favier B, Fliniaux I, Thelu J, Viallet JP, Demarchez M, Jahoda CA, Dhouailly D, Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators. Dev Dyn. 2000 Jul;218(3):426-37 |
2 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:262601 Huang Y, Hill J, Yatteau A, Wong L, Jiang T, Petrovic J, Gan L, Dong L, Wu DK, Reciprocal Negative Regulation Between Lmx1a and Lmo4 Is Required for Inner Ear Formation. J Neurosci. 2018 Jun 6;38(23):5429-5440 |
1* | J:60388 Ishii Y, Nakamura S, Osumi N, Demarcation of early mammalian cortical development by differential expression of fringe genes. Brain Res Dev Brain Res. 2000 Feb 7;119(2):307-20 |
1 | J:98458 Kiernan AE, Pelling AL, Leung KK, Tang AS, Bell DM, Tease C, Lovell-Badge R, Steel KP, Cheah KS, Sox2 is required for sensory organ development in the mammalian inner ear. Nature. 2005 Apr 21;434(7036):1031-5 |
1 | J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670 |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1* | J:61433 Pouyet L, Mitsiadis TA, Dynamic Lunatic fringe expression is correlated with boundaries formation in developing mouse teeth. Mech Dev. 2000 Mar 1;91(1-2):399-402 |
1 | J:50796 Thelu J, Viallet JP, Dhouailly D, Differential expression pattern of the three Fringe genes is associated with epidermal differentiation. J Invest Dermatol. 1998 Nov;111(5):903-6 |
1 | J:96850 van Tuyl M, Groenman F, Kuliszewski M, Ridsdale R, Wang J, Tibboel D, Post M, Overexpression of lunatic fringe does not affect epithelial cell differentiation in the developing mouse lung. Am J Physiol Lung Cell Mol Physiol. 2005 Apr;288(4):L672-82 |
1 | J:155893 Xu K, Nieuwenhuis E, Cohen BL, Wang W, Canty AJ, Danska JS, Coultas L, Rossant J, Wu MY, Piscione TD, Nagy A, Gossler A, Hicks GG, Hui CC, Henkelman RM, Yu LX, Sled JG, Gridley T, Egan SE, Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis. Am J Physiol Lung Cell Mol Physiol. 2010 Jan;298(1):L45-56 |
1* | J:173972 Zhao H, Li S, Han D, Kaartinen V, Chai Y, Alk5-mediated transforming growth factor beta signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol. 2011 May;31(10):2079-89 |
Lgals1 lectin, galactose binding, soluble 1 (Synonyms: Gal-1, Galbp, galectin-1, L14, Lect14) | |
Results | Reference |
1 | J:47227 Colnot C, Fowlis D, Ripoche MA, Bouchaert I, Poirier F, Embryonic implantation in galectin 1/galectin 3 double mutant mice. Dev Dyn. 1998 Apr;211(4):306-13 |
1 | J:54886 Lasserre C, Colnot C, Brechot C, Poirier F, HIP/PAP gene, encoding a C-type lectin overexpressed in primary liver cancer, is expressed in nervous system as well as in intestine and pancreas of the postimplantation mouse embryo. Am J Pathol. 1999 May;154(5):1601-10 |
1* | J:105234 Tenne-Brown J, Puche AC, Key B, Expression of galectin-1 in the mouse olfactory system. Int J Dev Biol. 1998 Sep;42(6):791-9 |
Lgals3 lectin, galactose binding, soluble 3 (Synonyms: gal3, galectin-3, L-34, Mac-2) | |
Results | Reference |
1 | J:47227 Colnot C, Fowlis D, Ripoche MA, Bouchaert I, Poirier F, Embryonic implantation in galectin 1/galectin 3 double mutant mice. Dev Dyn. 1998 Apr;211(4):306-13 |
1* | J:66902 Colnot C, Sidhu SS, Balmain N, Poirier F, Uncoupling of chondrocyte death and vascular invasion in mouse galectin 3 null mutant bones. Dev Biol. 2001 Jan 1;229(1):203-14 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:361142 Ke X, van Soldt B, Vlahos L, Zhou Y, Qian J, George J, Capdevila C, Glass I, Yan K, Califano A, Cardoso WV, Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate. Dev Cell. 2024 Dec 9; |
1 | J:117794 Sakakura Y, Hosokawa Y, Tsuruga E, Irie K, Nakamura M, Yajima T, Constributions of matrix metalloproteinases toward Meckel's cartilage resorption in mice: immunohistochemical studies, including comparisons with developing endochondral bones. Cell Tissue Res. 2006 Apr;328(1):137-51 |
1 | J:240148 Tan SY, Krasnow MA, Developmental origin of lung macrophage diversity. Development. 2016 Apr 15;143(8):1318-27 |
Lgals7 lectin, galactose binding, soluble 7 (Synonyms: Galectin-7, Pig1) | |
Results | Reference |
1 | J:56587 Timmons PM, Colnot C, Cail I, Poirier F, Magnaldo T, Expression of galectin-7 during epithelial development coincides with the onset of stratification. Int J Dev Biol. 1999 May;43(3):229-35 |
Lgr4 leucine-rich repeat-containing G protein-coupled receptor 4 (Synonyms: A330106J01Rik, A930009A08Rik, Gpr48) | |
Results | Reference |
1* | J:264603 Da Silva F, Massa F, Motamedi FJ, Vidal V, Rocha AS, Gregoire EP, Cai CL, Wagner KD, Schedl A, Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4. Dev Biol. 2018 Sep 1;441(1):42-51 |
1 | J:312814 Fernandez Vallone V, Leprovots M, Ribatallada-Soriano D, Gerbier R, Lefort A, Libert F, Vassart G, Garcia MI, LGR5 controls extracellular matrix production by stem cells in the developing intestine. EMBO Rep. 2020 Jul 3;21(7):e49224 |
1* | J:141686 Jin C, Yin F, Lin M, Li H, Wang Z, Weng J, Liu M, Da Dong X, Qu J, Tu L, GPR48 regulates epithelial cell proliferation and migration by activating EGFR during eyelid development. Invest Ophthalmol Vis Sci. 2008 Oct;49(10):4245-53 |
2* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
1 | J:152843 Luo J, Zhou W, Zhou X, Li D, Weng J, Yi Z, Cho SG, Li C, Yi T, Wu X, Li XY, de Crombrugghe B, Hook M, Liu M, Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development. 2009 Aug;136(16):2747-56 |
1 | J:139012 Mohri Y, Kato S, Umezawa A, Okuyama R, Nishimori K, Impaired hair placode formation with reduced expression of hair follicle-related genes in mice lacking Lgr4. Dev Dyn. 2008 Aug;237(8):2235-42 |
2* | J:172277 Mohri Y, Oyama K, Akamatsu A, Kato S, Nishimori K, Lgr4-deficient mice showed premature differentiation of ureteric bud with reduced expression of Wnt effector Lef1 and Gata3. Dev Dyn. 2011 Jun;240(6):1626-34 |
1 | J:134299 Weng J, Luo J, Cheng X, Jin C, Zhou X, Qu J, Tu L, Ai D, Li D, Wang J, Martin JF, Amendt BA, Liu M, Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6081-6 |
Lgr5 leucine rich repeat containing G protein coupled receptor 5 (Synonyms: Gpr49) | |
Results | Reference |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1* | J:264603 Da Silva F, Massa F, Motamedi FJ, Vidal V, Rocha AS, Gregoire EP, Cai CL, Wagner KD, Schedl A, Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4. Dev Biol. 2018 Sep 1;441(1):42-51 |
1* | J:311215 Fazilaty H, Brugger MD, Valenta T, Szczerba BM, Berkova L, Doumpas N, Hausmann G, Scharl M, Basler K, Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage. Cell Rep. 2021 Aug 3;36(5):109484 |
1 | J:312814 Fernandez Vallone V, Leprovots M, Ribatallada-Soriano D, Gerbier R, Lefort A, Libert F, Vassart G, Garcia MI, LGR5 controls extracellular matrix production by stem cells in the developing intestine. EMBO Rep. 2020 Jul 3;21(7):e49224 |
1* | J:150374 Garcia MI, Ghiani M, Lefort A, Libert F, Strollo S, Vassart G, LGR5 deficiency deregulates Wnt signaling and leads to precocious Paneth cell differentiation in the fetal intestine. Dev Biol. 2009 Jul 1;331(1):58-67 |
1* | J:231673 Gustin SE, Hogg K, Stringer JM, Rastetter RH, Pelosi E, Miles DC, Sinclair AH, Wilhelm D, Western PS, WNT/beta-catenin and p27/FOXL2 differentially regulate supporting cell proliferation in the developing ovary. Dev Biol. 2016 Apr 15;412(2):250-60 |
3* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
2 | J:353381 Kostic L, Leung C, Ahmad Murad K, Kancheva S, Perna S, Lee B, Barker N, Lgr5 marks stem/progenitor cells contributing to epithelial and muscle development in the mouse esophagus. Nat Commun. 2024 Aug 21;15(1):7145 |
1 | J:314598 Nik AM, Reyahi A, Ponten F, Carlsson P, Foxf2 in intestinal fibroblasts reduces numbers of Lgr5(+) stem cells and adenoma formation by inhibiting Wnt signaling. Gastroenterology. 2013 May;144(5):1001-11 |
2 | J:328944 Olbertova K, Hrckulak D, Kriz V, Jesionek W, Kubovciak J, Esner M, Korinek V, Buchtova M, Role of LGR5-positive mesenchymal cells in craniofacial development. Front Cell Dev Biol. 2022;10:810527 |
2 | J:216158 Rastetter RH, Bernard P, Palmer JS, Chassot AA, Chen H, Western PS, Ramsay RG, Chaboissier MC, Wilhelm D, Marker genes identify three somatic cell types in the fetal mouse ovary. Dev Biol. 2014 Oct 15;394(2):242-52 |
2 | J:340421 Ruscitto A, Chen P, Tosa I, Wang Z, Zhou G, Safina I, Wei R, Morel MM, Koch A, Forman M, Reeve G, Lecholop MK, Wilson M, Bonthius D, Chen M, Ono M, Wang TC, Yao H, Embree MC, Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity. Cell Stem Cell. 2023 Sep 7;30(9):1179-1198.e7 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1 | J:332922 Venkata VD, Jamaluddin MFB, Goad J, Drury HR, Tadros MA, Lim R, Karakoti A, O'Sullivan R, Ius Y, Jaaback K, Nahar P, Tanwar PS, Development and characterization of human fetal female reproductive tract organoids to understand Mullerian duct anomalies. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2118054119 |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
Lgr6 leucine-rich repeat-containing G protein-coupled receptor 6 (Synonyms: A530037C04Rik) | |
Results | Reference |
1* | J:264603 Da Silva F, Massa F, Motamedi FJ, Vidal V, Rocha AS, Gregoire EP, Cai CL, Wagner KD, Schedl A, Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4. Dev Biol. 2018 Sep 1;441(1):42-51 |
2* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
1* | J:157895 Snippert HJ, Haegebarth A, Kasper M, Jaks V, van Es JH, Barker N, van de Wetering M, van den Born M, Begthel H, Vries RG, Stange DE, Toftgard R, Clevers H, Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin. Science. 2010 Mar 12;327(5971):1385-9 |
1 | J:356085 Wang J, Tian GG, Zheng Z, Li B, Xing Q, Wu J, Comprehensive Transcriptomic Analysis of Mouse Gonadal Development Involving Sexual Differentiation, Meiosis and Gametogenesis. Biol Proced Online. 2019;21:20 |
Lhb luteinizing hormone beta (Synonyms: Gm29035, leutropin, LH) | |
Results | Reference |
1 | J:223814 Aujla PK, Bogdanovic V, Naratadam GT, Raetzman LT, Persistent expression of activated notch in the developing hypothalamus affects survival of pituitary progenitors and alters pituitary structure. Dev Dyn. 2015 Aug;244(8):921-34 |
1* | J:290740 Brachet C, Kozhemyakina EA, Boros E, Heinrichs C, Balikova I, Soblet J, Smits G, Vilain C, Mathers PH, Truncating RAX Mutations: Anophthalmia, Hypopituitarism, Diabetes Insipidus, and Cleft Palate in Mice and Men. J Clin Endocrinol Metab. 2019 Jul 1;104(7):2925-2930 |
1 | J:235668 Goldsmith S, Lovell-Badge R, Rizzoti K, SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitary. Development. 2016 Jul 1;143(13):2376-88 |
1* | J:19457 Japon MA, Rubinstein M, Low MJ, In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development. J Histochem Cytochem. 1994 Aug;42(8):1117-25 |
1 | J:140899 Million Passe CM, White CR, King MW, Quirk PL, Iovanna JL, Quirk CC, Loss of the protein NUPR1 (p8) leads to delayed LHB expression, delayed ovarian maturation, and testicular development of a sertoli-cell-only syndrome-like phenotype in mice. Biol Reprod. 2008 Oct;79(4):598-607 |
1 | J:81212 Quirk CC, Seachrist DD, Nilson JH, Embryonic Expression of the Luteinizing Hormone beta Gene Appears to Be Coupled to the Transient Appearance of p8, a High Mobility Group-related Transcription Factor. J Biol Chem. 2003 Jan 17;278(3):1680-5 |
1 | J:108374 Vesper AH, Raetzman LT, Camper SA, Role of prophet of Pit1 (PROP1) in gonadotrope differentiation and puberty. Endocrinology. 2006 Apr;147(4):1654-63 |
Lhfpl5 lipoma HMGIC fusion partner-like 5 (Synonyms: 9330179O15Rik, LOC328789, Tmhs) | |
Results | Reference |
1* | J:98396 Longo-Guess CM, Gagnon LH, Cook SA, Wu J, Zheng QY, Johnson KR, A missense mutation in the previously undescribed gene Tmhs underlies deafness in hurry-scurry (hscy) mice. Proc Natl Acad Sci U S A. 2005 May 31;102(22):7894-9 |
1* | J:125709 Longo-Guess CM, Gagnon LH, Fritzsch B, Johnson KR, Targeted knockout and lacZ reporter expression of the mouse Tmhs deafness gene and characterization of the hscy-2J mutation. Mamm Genome. 2007 Sep;18(9):646-56 |
1 | J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12) |
Lhpp phospholysine phosphohistidine inorganic pyrophosphate phosphatase (Synonyms: 2310007H09Rik) | |
Results | Reference |
1* | J:344835 Lin D, Li L, Chen WB, Chen J, Ren D, Zheng ZH, Zhao C, Zhong Y, Luo B, Jing H, Chen P, Zou S, Lai X, Zhou T, Ding N, Li L, Pan BX, Fei E, LHPP, a risk factor for major depressive disorder, regulates stress-induced depression-like behaviors through its histidine phosphatase activity. Mol Psychiatry. 2023 Feb;28(2):908-918 |
Lhx1 LIM homeobox protein 1 (Synonyms: Lim1) | |
Results | Reference |
1* | J:16971 Barnes JD, Crosby JL, Jones CM, Wright CV, Hogan BL, Embryonic expression of Lim-1, the mouse homolog of Xenopus Xlim-1, suggests a role in lateral mesoderm differentiation and neurogenesis. Dev Biol. 1994 Jan;161(1):168-78 |
1* | J:181601 Bassett EA, Korol A, Deschamps PA, Buettner R, Wallace VA, Williams T, West-Mays JA, Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29 |
1 | J:226607 Clegg JM, Li Z, Molinek M, Caballero IM, Manuel MN, Price DJ, Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons. Neural Dev. 2015;10(1):26 |
2* | J:16725 Fujii T, Pichel JG, Taira M, Toyama R, Dawid IB, Westphal H, Expression patterns of the murine LIM class homeobox gene lim1 in the developing brain and excretory system. Dev Dyn. 1994 Jan;199(1):73-83 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1 | J:153202 Gerber SD, Steinberg F, Beyeler M, Villiger PM, Trueb B, The murine Fgfrl1 receptor is essential for the development of the metanephric kidney. Dev Biol. 2009 Nov 1;335(1):106-19 |
1 | J:223559 Goetz JJ, Martin GM, Chowdhury R, Trimarchi JM, Onecut1 and Onecut2 play critical roles in the development of the mouse retina. PLoS One. 2014;9(10):e110194 |
1* | J:208898 Huang CC, Orvis GD, Kwan KM, Behringer RR, Lhx1 is required in Mullerian duct epithelium for uterine development. Dev Biol. 2014 May 15;389(2):124-36 |
1 | J:160335 Huang X, Liu J, Ketova T, Fleming JT, Grover VK, Cooper MK, Litingtung Y, Chiang C, Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8422-7 |
1 | J:105233 Karavanov AA, Saint-Jeannet JP, Karavanova I, Taira M, Dawid IB, The LIM homeodomain protein Lim-1 is widely expressed in neural, neural crest and mesoderm derivatives in vertebrate development. Int J Dev Biol. 1996 Apr;40(2):453-61 |
1 | J:222438 Klimova L, Antosova B, Kuzelova A, Strnad H, Kozmik Z, Onecut1 and Onecut2 transcription factors operate downstream of Pax6 to regulate horizontal cell development. Dev Biol. 2015 Jun 1;402(1):48-60 |
1* | J:133086 Kobayashi A, Shawlot W, Kania A, Behringer RR, Requirement of Lim1 for female reproductive tract development. Development. 2004 Feb;131(3):539-49 |
1 | J:263715 Lee B, Kim J, An T, Kim S, Patel EM, Raber J, Lee SK, Lee S, Lee JW, Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons. Nat Commun. 2018 May 23;9(1):2026 |
2 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1 | J:60703 Liu W, Wang JH, Xiang M, Specific expression of the LIM/homeodomain protein Lim-1 in horizontal cells during retinogenesis. Dev Dyn. 2000 Mar;217(3):320-5 |
1 | J:164005 Miyata T, Ono Y, Okamoto M, Masaoka M, Sakakibara A, Kawaguchi A, Hashimoto M, Ogawa M, Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum. Neural Dev. 2010;5:23 |
2* | J:68840 Nakagawa Y, O'Leary DD, Combinatorial expression patterns of LIM-homeodomain and other regulatory genes parcellate developing thalamus. J Neurosci. 2001 Apr 15;21(8):2711-25 |
1 | J:120229 Narlis M, Grote D, Gaitan Y, Boualia SK, Bouchard M, Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney. J Am Soc Nephrol. 2007 Apr;18(4):1121-9 |
1* | J:263835 Newman EA, Kim DW, Wan J, Wang J, Qian J, Blackshaw S, Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes. Dev Biol. 2018 Jul 15;439(2):102-111 |
1 | J:130904 Poche RA, Kwan KM, Raven MA, Furuta Y, Reese BE, Behringer RR, Lim1 is essential for the correct laminar positioning of retinal horizontal cells. J Neurosci. 2007 Dec 19;27(51):14099-107 |
1 | J:133489 Qiu F, Jiang H, Xiang M, A comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursors. J Neurosci. 2008 Mar 26;28(13):3392-403 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:233479 Vong KI, Leung CK, Behringer RR, Kwan KM, Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum. Mol Brain. 2015;8:25 |
1 | J:242933 Whittaker DE, Riegman KL, Kasah S, Mohan C, Yu T, Sala BP, Hebaishi H, Caruso A, Marques AC, Michetti C, Smachetti ME, Shah A, Sabbioni M, Kulhanci O, Tee WW, Reinberg D, Scattoni ML, Volk H, McGonnell I, Wardle FC, Fernandes C, Basson MA, The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression. J Clin Invest. 2017 Mar 01;127(3):874-887 |
1 | J:89175 Woodside KJ, Shen H, Muntzel C, Daller JA, Sommers CL, Love PE, Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes. Gene Expr Patterns. 2004 May;4(3):315-20 |
2 | J:123471 Zhao Y, Kwan KM, Mailloux CM, Lee WK, Grinberg A, Wurst W, Behringer RR, Westphal H, LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum. Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13182-6 |
Lhx1os LIM homeobox 1, opposite strand (Synonyms: 1500016L03Rik, Lhx1as, ln-CR7) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Lhx2 LIM homeobox protein 2 (Synonyms: ap, apterous, Lh-2, LH2A) | |
Results | Reference |
1 | J:235552 Chinn GA, Hirokawa KE, Chuang TM, Urbina C, Patel F, Fong J, Funatsu N, Monuki ES, Agenesis of the Corpus Callosum Due to Defective Glial Wedge Formation in Lhx2 Mutant Mice. Cereb Cortex. 2015 Sep;25(9):2707-18 |
1 | J:133461 Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH, Schier AF, Dulac C, Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 2008 Jan 10;57(1):41-55 |
1* | J:332642 Cohen-Gulkar M, David A, Messika-Gold N, Eshel M, Ovadia S, Zuk-Bar N, Idelson M, Cohen-Tayar Y, Reubinoff B, Ziv T, Shamay M, Elkon R, Ashery-Padan R, The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration. PLoS Biol. 2023 Jan;21(1):e3001924 |
1* | J:184357 Dye CA, El Shawa H, Huffman KJ, A lifespan analysis of intraneocortical connections and gene expression in the mouse I. Cereb Cortex. 2011 Jun;21(6):1311-30 |
1* | J:178994 Fantauzzo KA, Christiano AM, Trps1 activates a network of secreted Wnt inhibitors and transcription factors crucial to vibrissa follicle morphogenesis. Development. 2012 Jan;139(1):203-14 |
1 | J:202029 Folgueras AR, Guo X, Pasolli HA, Stokes N, Polak L, Zheng D, Fuchs E, Architectural niche organization by LHX2 is linked to hair follicle stem cell function. Cell Stem Cell. 2013 Sep 5;13(3):314-27 |
1 | J:237540 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R, The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development. 2016 Nov 15;143(22):4182-4192 |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
1* | J:199301 Lavado A, He Y, Pare J, Neale G, Olson EN, Giovannini M, Cao X, Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34 |
1 | J:324116 Morita R, Sanzen N, Sasaki H, Hayashi T, Umeda M, Yoshimura M, Yamamoto T, Shibata T, Abe T, Kiyonari H, Furuta Y, Nikaido I, Fujiwara H, Tracing the origin of hair follicle stem cells. Nature. 2021 Jun;594(7864):547-552 |
1* | J:68840 Nakagawa Y, O'Leary DD, Combinatorial expression patterns of LIM-homeodomain and other regulatory genes parcellate developing thalamus. J Neurosci. 2001 Apr 15;21(8):2711-25 |
1* | J:51994 Retaux S, Rogard M, Bach I, Failli V, Besson MJ, Lhx9: a novel LIM-homeodomain gene expressed in the developing forebrain. J Neurosci. 1999 Jan 15;19(2):783-93 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:238111 Shirokova V, Biggs LC, Jussila M, Ohyama T, Groves AK, Mikkola ML, Foxi3 Deficiency Compromises Hair Follicle Stem Cell Specification and Activation. Stem Cells. 2016 Jul;34(7):1896-908 |
1 | J:159209 Tornqvist G, Sandberg A, Hagglund AC, Carlsson L, Cyclic expression of lhx2 regulates hair formation. PLoS Genet. 2010;6(4):e1000904 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1 | J:150808 Tuoc TC, Radyushkin K, Tonchev AB, Pinon MC, Ashery-Padan R, Molnar Z, Davidoff MS, Stoykova A, Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice. J Neurosci. 2009 Jul 1;29(26):8335-49 |
1 | J:89175 Woodside KJ, Shen H, Muntzel C, Daller JA, Sommers CL, Love PE, Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes. Gene Expr Patterns. 2004 May;4(3):315-20 |
Lhx3 LIM homeobox protein 3 (Synonyms: Lim3, mLim-3, P-LIM) | |
Results | Reference |
1* | J:73085 Dasen JS, Barbera JP, Herman TS, Connell SO, Olson L, Ju B, Tollkuhn J, Baek SH, Rose DW, Rosenfeld MG, Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 1;15(23):3193-207 |
1* | J:121318 Davis SW, Camper SA, Noggin regulates Bmp4 activity during pituitary induction. Dev Biol. 2007 May 1;305(1):145-60 |
1 | J:195620 Gumbel JH, Patterson EM, Owusu SA, Kabat BE, Jung DO, Simmons J, Hopkins T, Ellsworth BS, The forkhead transcription factor, Foxd1, is necessary for pituitary luteinizing hormone expression in mice. PLoS One. 2012;7(12):e52156 |
1 | J:119779 Hertzano R, Dror AA, Montcouquiol M, Ahmed ZM, Ellsworth B, Camper S, Friedman TB, Kelley MW, Avraham KB, Lhx3, a LIM domain transcription factor, is regulated by Pou4f3 in the auditory but not in the vestibular system. Eur J Neurosci. 2007 Feb;25(4):999-1005 |
1 | J:89175 Woodside KJ, Shen H, Muntzel C, Daller JA, Sommers CL, Love PE, Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes. Gene Expr Patterns. 2004 May;4(3):315-20 |
2* | J:261409 Xu M, Xie X, Dong X, Liang G, Gan L, Generation and characterization of Lhx3(GFP) reporter knockin and Lhx3(loxP) conditional knockout mice. Genesis. 2018 Apr;56(4):e23098 |
1* | J:24499 Zhadanov AB, Bertuzzi S, Taira M, Dawid IB, Westphal H, Expression pattern of the murine LIM class homeobox gene Lhx3 in subsets of neural and neuroendocrine tissues. Dev Dyn. 1995 Apr;202(4):354-64 |
Lhx4 LIM homeobox protein 4 (Synonyms: A330062J17Rik, Gsh-4, Gsh4) | |
Results | Reference |
1* | J:130196 Alfonsi F, Filippi P, Salaun D, deLapeyriere O, Durbec P, LIFR beta plays a major role in neuronal identity determination and glial differentiation in the mouse facial nucleus. Dev Biol. 2008 Jan 1;313(1):267-78 |
1* | J:19373 Li H, Witte DP, Branford WW, Aronow BJ, Weinstein M, Kaur S, Wert S, Singh G, Schreiner CM, Whitsett JA, Scott WJ, Potter SS, Gsh-4 encodes a LIM-type homeodomain, is expressed in the developing central nervous system and is required for early postnatal survival. EMBO J. 1994 Jun 15;13(12):2876-85 |
1 | J:89175 Woodside KJ, Shen H, Muntzel C, Daller JA, Sommers CL, Love PE, Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes. Gene Expr Patterns. 2004 May;4(3):315-20 |
Lhx5 LIM homeobox protein 5 (Synonyms: Lim2) | |
Results | Reference |
1* | J:187352 Abellan A, Vernier B, Retaux S, Medina L, Similarities and differences in the forebrain expression of Lhx1 and Lhx5 between chicken and mouse: Insights for understanding telencephalic development and evolution. J Comp Neurol. 2010 Sep 1;518(17):3512-28 |
1 | J:175586 Bupesh M, Legaz I, Abellan A, Medina L, Multiple telencephalic and extratelencephalic embryonic domains contribute neurons to the medial extended amygdala. J Comp Neurol. 2011 Jun 1;519(8):1505-25 |
1 | J:226607 Clegg JM, Li Z, Molinek M, Caballero IM, Manuel MN, Price DJ, Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons. Neural Dev. 2015;10(1):26 |
1 | J:237540 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R, The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development. 2016 Nov 15;143(22):4182-4192 |
1 | J:160335 Huang X, Liu J, Ketova T, Fleming JT, Grover VK, Cooper MK, Litingtung Y, Chiang C, Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8422-7 |
1 | J:263715 Lee B, Kim J, An T, Kim S, Patel EM, Raber J, Lee SK, Lee S, Lee JW, Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons. Nat Commun. 2018 May 23;9(1):2026 |
1 | J:164005 Miyata T, Ono Y, Okamoto M, Masaoka M, Sakakibara A, Kawaguchi A, Hashimoto M, Ogawa M, Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum. Neural Dev. 2010;5:23 |
2* | J:68840 Nakagawa Y, O'Leary DD, Combinatorial expression patterns of LIM-homeodomain and other regulatory genes parcellate developing thalamus. J Neurosci. 2001 Apr 15;21(8):2711-25 |
1* | J:38197 Sheng HZ, Bertuzzi S, Chiang C, Shawlot W, Taira M, Dawid I, Westphal H, Expression of murine Lhx5 suggests a role in specifying the forebrain. Dev Dyn. 1997 Feb;208(2):266-77 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:242933 Whittaker DE, Riegman KL, Kasah S, Mohan C, Yu T, Sala BP, Hebaishi H, Caruso A, Marques AC, Michetti C, Smachetti ME, Shah A, Sabbioni M, Kulhanci O, Tee WW, Reinberg D, Scattoni ML, Volk H, McGonnell I, Wardle FC, Fernandes C, Basson MA, The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression. J Clin Invest. 2017 Mar 01;127(3):874-887 |
1 | J:89175 Woodside KJ, Shen H, Muntzel C, Daller JA, Sommers CL, Love PE, Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes. Gene Expr Patterns. 2004 May;4(3):315-20 |
1 | J:123471 Zhao Y, Kwan KM, Mailloux CM, Lee WK, Grinberg A, Wurst W, Behringer RR, Westphal H, LIM-homeodomain proteins Lhx1 and Lhx5, and their cofactor Ldb1, control Purkinje cell differentiation in the developing cerebellum. Proc Natl Acad Sci U S A. 2007 Aug 7;104(32):13182-6 |
Lhx6 LIM homeobox protein 6 | |
Results | Reference |
1 | J:328140 Asgarian Z, Oliveira MG, Stryjewska A, Maragkos I, Rubin AN, Magno L, Pachnis V, Ghorbani M, Hiebert SW, Denaxa M, Kessaris N, MTG8 interacts with LHX6 to specify cortical interneuron subtype identity. Nat Commun. 2022 Sep 5;13(1):5217 |
1 | J:160574 Bithell A, Hsu T, Kandanearatchi A, Landau S, Everall IP, Tsuang MT, Chana G, Williams BP, Expression of the Rap1 guanine nucleotide exchange factor, MR-GEF, is altered in individuals with bipolar disorder. PLoS One. 2010;5(4):e10392 |
1 | J:121201 Chen L, Liao G, Waclaw RR, Burns KA, Linquist D, Campbell K, Zheng Y, Kuan CY, Rac1 controls the formation of midline commissures and the competency of tangential migration in ventral telencephalic neurons. J Neurosci. 2007 Apr 4;27(14):3884-93 |
1 | J:126582 Cobos I, Borello U, Rubenstein JL, Dlx transcription factors promote migration through repression of axon and dendrite growth. Neuron. 2007 Jun 21;54(6):873-88 |
1 | J:336861 Folorunso OO, Brown SE, Baruah J, Harvey TL, Jami SA, Radzishevsky I, Wolosker H, McNally JM, Gray JA, Vasudevan A, Balu DT, D-serine availability modulates prefrontal cortex inhibitory interneuron development and circuit maturation. Sci Rep. 2023 Jun 13;13(1):9595 |
1 | J:163224 Garcia-Lopez M, Abellan A, Legaz I, Rubenstein JL, Puelles L, Medina L, Histogenetic compartments of the mouse centromedial and extended amygdala based on gene expression patterns during development. J Comp Neurol. 2008 Jan 1;506(1):46-74 |
1 | J:327415 Jing J, Feng J, Yuan Y, Guo T, Lei J, Pei F, Ho TV, Chai Y, Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022 Aug 16;13(1):4803 |
1 | J:198772 Katayama K, Imai F, Campbell K, Lang RA, Zheng Y, Yoshida Y, RhoA and Cdc42 are required in pre-migratory progenitors of the medial ganglionic eminence ventricular zone for proper cortical interneuron migration. Development. 2013 Aug;140(15):3139-45 |
1 | J:336092 Knowles SJ, Stafford AM, Zaman T, Angara K, Williams MR, Newbern JM, Vogt D, Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs. Development. 2023 May 15;150(10):dev201371 |
2 | J:119476 Liodis P, Denaxa M, Grigoriou M, Akufo-Addo C, Yanagawa Y, Pachnis V, Lhx6 activity is required for the normal migration and specification of cortical interneuron subtypes. J Neurosci. 2007 Mar 21;27(12):3078-89 |
2 | J:132219 Lopez-Bendito G, Sanchez-Alcaniz JA, Pla R, Borrell V, Pico E, Valdeolmillos M, Marin O, Chemokine signaling controls intracortical migration and final distribution of GABAergic interneurons. J Neurosci. 2008 Feb 13;28(7):1613-24 |
1 | J:254523 Magno L, Barry C, Schmidt-Hieber C, Theodotou P, Hausser M, Kessaris N, NKX2-1 Is Required in the Embryonic Septum for Cholinergic System Development, Learning, and Memory. Cell Rep. 2017 Aug 15;20(7):1572-1584 |
1* | J:102348 Nery S, Corbin JG, Fishell G, Dlx2 progenitor migration in wild type and Nkx2.1 mutant telencephalon. Cereb Cortex. 2003 Sep;13(9):895-903 |
1* | J:110037 Pla R, Borrell V, Flames N, Marin O, Layer acquisition by cortical GABAergic interneurons is independent of Reelin signaling. J Neurosci. 2006 Jun 28;26(26):6924-34 |
1* | J:283877 Sanchez-Alcaniz JA, Haege S, Mueller W, Pla R, Mackay F, Schulz S, Lopez-Bendito G, Stumm R, Marin O, Cxcr7 controls neuronal migration by regulating chemokine responsiveness. Neuron. 2011 Jan 13;69(1):77-90 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:235556 Tivodar S, Kalemaki K, Kounoupa Z, Vidaki M, Theodorakis K, Denaxa M, Kessaris N, de Curtis I, Pachnis V, Karagogeos D, Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons. Cereb Cortex. 2015 Sep;25(9):2370-82 |
1 | J:197638 van den Berghe V, Stappers E, Vandesande B, Dimidschstein J, Kroes R, Francis A, Conidi A, Lesage F, Dries R, Cazzola S, Berx G, Kessaris N, Vanderhaeghen P, van Ijcken W, Grosveld FG, Goossens S, Haigh JJ, Fishell G, Goffinet A, Aerts S, Huylebroeck D, Seuntjens E, Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1. Neuron. 2013 Jan 9;77(1):70-82 |
1 | J:304564 Venkataramanappa S, Schutz D, Saaber F, Kumar PA, Abe P, Schulz S, Stumm R, The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS Genet. 2021 Mar;17(3):e1009441 |
1 | J:193303 Vidaki M, Tivodar S, Doulgeraki K, Tybulewicz V, Kessaris N, Pachnis V, Karagogeos D, Rac1-dependent cell cycle exit of MGE precursors and GABAergic interneuron migration to the cortex. Cereb Cortex. 2012 Mar;22(3):680-92 |
1 | J:159849 Wang Y, Dye CA, Sohal V, Long JE, Estrada RC, Roztocil T, Lufkin T, Deisseroth K, Baraban SC, Rubenstein JL, Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneurons. J Neurosci. 2010 Apr 14;30(15):5334-45 |
Lhx8 LIM homeobox protein 8 (Synonyms: L3, Lhx7) | |
Results | Reference |
1 | J:213234 Cho HH, Cargnin F, Kim Y, Lee B, Kwon RJ, Nam H, Shen R, Barnes AP, Lee JW, Lee S, Lee SK, Isl1 directly controls a cholinergic neuronal identity in the developing forebrain and spinal cord by forming cell type-specific complexes. PLoS Genet. 2014 Apr;10(4):e1004280 |
1 | J:154447 Fragkouli A, van Wijk NV, Lopes R, Kessaris N, Pachnis V, LIM homeodomain transcription factor-dependent specification of bipotential MGE progenitors into cholinergic and GABAergic striatal interneurons. Development. 2009 Nov;136(22):3841-51 |
1 | J:163224 Garcia-Lopez M, Abellan A, Legaz I, Rubenstein JL, Puelles L, Medina L, Histogenetic compartments of the mouse centromedial and extended amygdala based on gene expression patterns during development. J Comp Neurol. 2008 Jan 1;506(1):46-74 |
1 | J:182013 Lopes R, Verhey van Wijk N, Neves G, Pachnis V, Transcription factor LIM homeobox 7 (Lhx7) maintains subtype identity of cholinergic interneurons in the mammalian striatum. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3119-24 |
1 | J:254523 Magno L, Barry C, Schmidt-Hieber C, Theodotou P, Hausser M, Kessaris N, NKX2-1 Is Required in the Embryonic Septum for Cholinergic System Development, Learning, and Memory. Cell Rep. 2017 Aug 15;20(7):1572-1584 |
1* | J:83508 Shibaguchi T, Kato J, Abe M, Tamamura Y, Tabata MJ, Liu JG, Iwamoto M, Wakisaka S, Wanaka A, Kurisu K, Expression and role of Lhx8 in murine tooth development. Arch Histol Cytol. 2003 Mar;66(1):95-108 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:244395 Shin YH, Ren Y, Suzuki H, Golnoski KJ, Ahn HW, Mico V, Rajkovic A, Transcription factors SOHLH1 and SOHLH2 coordinate oocyte differentiation without affecting meiosis I. J Clin Invest. 2017 Jun 01;127(6):2106-2117 |
1 | J:297097 Sorrenti M, Klinger FG, Iona S, Rossi V, Marcozzi S, DE Felici M, Expression and possible roles of extracellular signal-related kinases 1-2 (ERK1-2) in mouse primordial germ cell development. J Reprod Dev. 2020 Oct 13;66(5):399-409 |
1 | J:84641 Zhao Y, Marin O, Hermesz E, Powell A, Flames N, Palkovits M, Rubenstein JL, Westphal H, The LIM-homeobox gene Lhx8 is required for the development of many cholinergic neurons in the mouse forebrain. Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):9005-10 |
1 | J:315014 Zhou C, Chen D, Ren J, Huang D, Li R, Luo H, Guan C, Cao Y, Wang W, FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex. J Cell Mol Med. 2021 Mar;25(6):3051-3062 |
Lhx9 LIM homeobox protein 9 (Synonyms: 3110009O07Rik, LH2B, Lhx9 alpha) | |
Results | Reference |
1 | J:163224 Garcia-Lopez M, Abellan A, Legaz I, Rubenstein JL, Puelles L, Medina L, Histogenetic compartments of the mouse centromedial and extended amygdala based on gene expression patterns during development. J Comp Neurol. 2008 Jan 1;506(1):46-74 |
1* | J:79830 Garel S, Yun K, Grosschedl R, Rubenstein JL, The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development. 2002 Dec;129(24):5621-34 |
1 | J:206577 Green MJ, Myat AM, Emmenegger BA, Wechsler-Reya RJ, Wilson LJ, Wingate RJ, Independently specified Atoh1 domains define novel developmental compartments in rhombomere 1. Development. 2014 Jan;141(2):389-98 |
1* | J:207495 Green MJ, Wingate RJ, Developmental origins of diversity in cerebellar output nuclei. Neural Dev. 2014;9:1 |
2 | J:315293 Kumamoto T, Toma K, Gunadi, McKenna WL, Kasukawa T, Katzman S, Chen B, Hanashima C, Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013 Mar 28;3(3):931-45 |
1 | J:199727 Lokmane L, Proville R, Narboux-Neme N, Gyory I, Keita M, Mailhes C, Lena C, Gaspar P, Grosschedl R, Garel S, Sensory map transfer to the neocortex relies on pretarget ordering of thalamic axons. Curr Biol. 2013 May 6;23(9):810-6 |
1* | J:68840 Nakagawa Y, O'Leary DD, Combinatorial expression patterns of LIM-homeodomain and other regulatory genes parcellate developing thalamus. J Neurosci. 2001 Apr 15;21(8):2711-25 |
1* | J:51994 Retaux S, Rogard M, Bach I, Failli V, Besson MJ, Lhx9: a novel LIM-homeodomain gene expressed in the developing forebrain. J Neurosci. 1999 Jan 15;19(2):783-93 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:212053 Takasawa K, Kashimada K, Pelosi E, Takagi M, Morio T, Asahara H, Schlessinger D, Mizutani S, Koopman P, FOXL2 transcriptionally represses Sf1 expression by antagonizing WT1 during ovarian development in mice. FASEB J. 2014 May;28(5):2020-8 |
1* | J:104160 Tole S, Gutin G, Bhatnagar L, Remedios R, Hebert JM, Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev Biol. 2006 Jan 1;289(1):141-51 |
1* | J:287411 Tran HN, Park W, Seong S, Jeong JE, Nguyen QH, Yoon J, Baek K, Jeong Y, Tcf7l2 transcription factor is required for the maintenance, but not the initial specification, of the neurotransmitter identity in the caudal thalamus. Dev Dyn. 2020 May;249(5):646-655 |
1 | J:89175 Woodside KJ, Shen H, Muntzel C, Daller JA, Sommers CL, Love PE, Expression of Dlx and Lhx family homeobox genes in fetal thymus and thymocytes. Gene Expr Patterns. 2004 May;4(3):315-20 |
Lif leukemia inhibitory factor | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:105646 Oberle S, Schober A, Meyer V, Holtmann B, Henderson C, Sendtner M, Unsicker K, Loss of leukemia inhibitory factor receptor beta or cardiotrophin-1 causes similar deficits in preganglionic sympathetic neurons and adrenal medulla. J Neurosci. 2006 Feb 8;26(6):1823-32 |
1 | J:161760 Provost PR, Simard M, Tremblay Y, A link between lung androgen metabolism and the emergence of mature epithelial type II cells. Am J Respir Crit Care Med. 2004 Aug 1;170(3):296-305 |
1* | J:14393 Robertson M, Chambers I, Rathjen P, Nichols J, Smith A, Expression of alternative forms of differentiation inhibiting activity (DIA/LIF) during murine embryogenesis and in neonatal and adult tissues. Dev Genet. 1993;14(3):165-73 |
1 | J:314320 Wang H, Kane AW, Lee C, Ahn S, Gli3 repressor controls cell fates and cell adhesion for proper establishment of neurogenic niche. Cell Rep. 2014 Aug 21;8(4):1093-104 |
Lifr LIF receptor alpha (Synonyms: A230075M04Rik, soluble differentiation-stimulating factor receptor) | |
Results | Reference |
1* | J:130196 Alfonsi F, Filippi P, Salaun D, deLapeyriere O, Durbec P, LIFR beta plays a major role in neuronal identity determination and glial differentiation in the mouse facial nucleus. Dev Biol. 2008 Jan 1;313(1):267-78 |
1 | J:242320 Kosfeld A, Brand F, Weiss AC, Kreuzer M, Goerk M, Martens H, Schubert S, Schafer AK, Riehmer V, Hennies I, Brasen JH, Pape L, Amann K, Krogvold L, Bjerre A, Daniel C, Kispert A, Haffner D, Weber RG, Mutations in the leukemia inhibitory factor receptor (LIFR) gene and Lifr deficiency cause urinary tract malformations. Hum Mol Genet. 2017 May 01;26(9):1716-1731 |
1 | J:105646 Oberle S, Schober A, Meyer V, Holtmann B, Henderson C, Sendtner M, Unsicker K, Loss of leukemia inhibitory factor receptor beta or cardiotrophin-1 causes similar deficits in preganglionic sympathetic neurons and adrenal medulla. J Neurosci. 2006 Feb 8;26(6):1823-32 |
1* | J:31858 Owczarek CM, Layton MJ, Robb LG, Nicola NA, Begley CG, Molecular basis of the soluble and membrane-bound forms of the murine leukemia inhibitory factor receptor alpha-chain. Expression in normal, gestating, and leukemia inhibitory factor nullizygous mice. J Biol Chem. 1996 Mar 8;271(10):5495-504 |
1 | J:314320 Wang H, Kane AW, Lee C, Ahn S, Gli3 repressor controls cell fates and cell adhesion for proper establishment of neurogenic niche. Cell Rep. 2014 Aug 21;8(4):1093-104 |
Limch1 LIM and calponin homology domains 1 (Synonyms: 3732412D22Rik, mKIAA1102) | |
Results | Reference |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
Limd1 LIM domains containing 1 (Synonyms: D9Ertd192e) | |
Results | Reference |
1 | J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005 |
Limk1 LIM domain kinase 1 | |
Results | Reference |
1 | J:167714 Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, Chen H, Haneline LS, Chan RJ, Schwartz RJ, Field LJ, Atkinson SJ, Shou W, Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development. 2011 Jan;138(2):303-15 |
1* | J:170390 Lindstrom NO, Neves C, McIntosh R, Miedzybrodzka Z, Vargesson N, Martin Collinson J, Tissue specific characterisation of Lim-kinase 1 expression during mouse embryogenesis. Gene Expr Patterns. 2011 Mar-Apr;11(3-4):221-32 |
1 | J:29439 Proschel C, Blouin MJ, Gutowski NJ, Ludwig R, Noble M, Limk1 is predominantly expressed in neural tissues and phosphorylates serine, threonine and tyrosine residues in vitro. Oncogene. 1995 Oct 5;11(7):1271-81 |
Lin9 lin-9 DREAM MuvB core complex component (Synonyms: 2700022J23Rik) | |
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2 | J:290729 Grundl M, Walz S, Hauf L, Schwab M, Werner KM, Spahr S, Schulte C, Maric HM, Ade CP, Gaubatz S, Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes. PLoS Genet. 2020 May;16(5):e1008818 |
Lin28a lin-28 homolog A (Synonyms: Lin-28, Lin28, Lin28a, Tex17) | |
Results | Reference |
1* | J:207057 Bhuiyan MI, Lee JH, Kim SY, Cho KO, Expression of exogenous LIN28 contributes to proliferation and survival of mouse primary cortical neurons in vitro. Neuroscience. 2013 Sep 17;248:448-58 |
1 | J:316527 Chen HH, Welling M, Bloch DB, Munoz J, Mientjes E, Chen X, Tramp C, Wu J, Yabuuchi A, Chou YF, Buecker C, Krainer A, Willemsen R, Heck AJ, Geijsen N, DAZL limits pluripotency, differentiation, and apoptosis in developing primordial germ cells. Stem Cell Reports. 2014 Nov 11;3(5):892-904 |
2* | J:252127 Dong N, Liu Y, Zhang T, Zhao L, Tian J, Ruan J, Different expression patterns of Lin28 and Lin28b in mouse molar development. Arch Oral Biol. 2017 Oct;82:280-285 |
1 | J:250152 Hu X, Tang Z, Li Y, Liu W, Zhang S, Wang B, Tian Y, Zhao Y, Ran H, Liu W, Feng GS, Shuai J, Wang H, Lu Z, Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice. Sci Rep. 2015 Aug 12;5:12982 |
1* | J:214596 Nguyen LH, Robinton DA, Seligson MT, Wu L, Li L, Rakheja D, Comerford SA, Ramezani S, Sun X, Parikh MS, Yang EH, Powers JT, Shinoda G, Shah SP, Hammer RE, Daley GQ, Zhu H, Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models. Cancer Cell. 2014 Aug 11;26(2):248-61 |
2 | J:321070 Osborne JK, Kinney MA, Han A, Akinnola KE, Yermalovich AV, Vo LT, Pearson DS, Sousa PM, Ratanasirintrawoot S, Tsanov KM, Barragan J, North TE, Metzger RJ, Daley GQ, Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021 Jul 20;36(3):109408 |
1 | J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34 |
1 | J:221409 Yang M, Yang SL, Herrlinger S, Liang C, Dzieciatkowska M, Hansen KC, Desai R, Nagy A, Niswander L, Moss EG, Chen JF, Lin28 promotes the proliferative capacity of neural progenitor cells in brain development. Development. 2015 May 1;142(9):1616-27 |
2 | J:270550 Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ, Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan 11;10(1):168 |
Lin28b lin-28 homolog B (Synonyms: 2810403D23Rik, D030047M17Rik) | |
Results | Reference |
2* | J:252127 Dong N, Liu Y, Zhang T, Zhao L, Tian J, Ruan J, Different expression patterns of Lin28 and Lin28b in mouse molar development. Arch Oral Biol. 2017 Oct;82:280-285 |
1 | J:223798 Golden EJ, Benito-Gonzalez A, Doetzlhofer A, The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3864-73 |
1* | J:214596 Nguyen LH, Robinton DA, Seligson MT, Wu L, Li L, Rakheja D, Comerford SA, Ramezani S, Sun X, Parikh MS, Yang EH, Powers JT, Shinoda G, Shah SP, Hammer RE, Daley GQ, Zhu H, Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models. Cancer Cell. 2014 Aug 11;26(2):248-61 |
2 | J:321070 Osborne JK, Kinney MA, Han A, Akinnola KE, Yermalovich AV, Vo LT, Pearson DS, Sousa PM, Ratanasirintrawoot S, Tsanov KM, Barragan J, North TE, Metzger RJ, Daley GQ, Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021 Jul 20;36(3):109408 |
1 | J:221409 Yang M, Yang SL, Herrlinger S, Liang C, Dzieciatkowska M, Hansen KC, Desai R, Nagy A, Niswander L, Moss EG, Chen JF, Lin28 promotes the proliferative capacity of neural progenitor cells in brain development. Development. 2015 May 1;142(9):1616-27 |
2 | J:270550 Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ, Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan 11;10(1):168 |
Lingo1 leucine rich repeat and Ig domain containing 1 (Synonyms: 4930471K13Rik, LERN1, LINGO-1, Lrrn6a, UNQ201) | |
Results | Reference |
1* | J:132770 Haines BP, Rigby PW, Expression of the Lingo/LERN gene family during mouse embryogenesis. Gene Expr Patterns. 2008 Jan;8(2):79-86 |
Lingo2 leucine rich repeat and Ig domain containing 2 (Synonyms: B230217C06Rik, LERN3, Lrrn6c) | |
Results | Reference |
1* | J:132770 Haines BP, Rigby PW, Expression of the Lingo/LERN gene family during mouse embryogenesis. Gene Expr Patterns. 2008 Jan;8(2):79-86 |
Lingo3 leucine rich repeat and Ig domain containing 3 (Synonyms: LERN2) | |
Results | Reference |
1* | J:132770 Haines BP, Rigby PW, Expression of the Lingo/LERN gene family during mouse embryogenesis. Gene Expr Patterns. 2008 Jan;8(2):79-86 |
Lingo4 leucine rich repeat and Ig domain containing 4 (Synonyms: A530050P17Rik, LERN4, Lrrn6d) | |
Results | Reference |
1* | J:132770 Haines BP, Rigby PW, Expression of the Lingo/LERN gene family during mouse embryogenesis. Gene Expr Patterns. 2008 Jan;8(2):79-86 |
Lipe lipase, hormone sensitive (Synonyms: 4933403G17Rik, HSL) | |
Results | Reference |
1* | J:236180 Zhou H, Black SM, Benson TW, Weintraub NL, Chen W, Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is Not Required for Brown Adipogenesis but Regulates Brown Adipose Tissue Development and Function. Mol Cell Biol. 2016 Aug 1;36(15):2027-38 |
Litchi long non-coding RNA in Chat intron (Synonyms: Gm2990) | |
Results | Reference |
1 | J:345795 Hsu HC, Hsu SP, Hsu FY, Chang M, Chen JA, LncRNA Litchi is a regulator for harmonizing maturity and resilient functionality in spinal motor neurons. iScience. 2024 Mar 15;27(3):109207 |
Llgl1 LLGL1 scribble cell polarity complex component (Synonyms: Lgl1) | |
Results | Reference |
1 | J:241995 Jossin Y, Lee M, Klezovitch O, Kon E, Cossard A, Lien WH, Fernandez TE, Cooper JA, Vasioukhin V, Llgl1 Connects Cell Polarity with Cell-Cell Adhesion in Embryonic Neural Stem Cells. Dev Cell. 2017 Jun 05;41(5):481-495.e5 |
Llgl2 LLGL2 scribble cell polarity complex component (Synonyms: 9130006H11Rik, MGC:27928) | |
Results | Reference |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
Lman1 lectin, mannose-binding, 1 (Synonyms: 2610020P13Rik, ERGIC53, F5F8D, gp58, MCFD1, MR60, P58) | |
Results | Reference |
1 | J:341713 Aure MH, Symonds JM, Villapudua CU, Dodge JT, Werner S, Knosp WM, Hoffman MP, FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation. Nat Commun. 2023 Oct 14;14(1):6485 |
Lmbrd1 LMBR1 domain containing 1 (Synonyms: 0910001K20Rik) | |
Results | Reference |
1 | J:281878 Yook C, Kim K, Kim D, Kang H, Kim SG, Kim E, Kim SY, A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice. Front Mol Neurosci. 2019;12:241 |
Lmcd1 LIM and cysteine-rich domains 1 (Synonyms: dyxin) | |
Results | Reference |
1* | J:101354 Rath N, Wang Z, Lu MM, Morrisey EE, LMCD1/Dyxin is a novel transcriptional cofactor that restricts GATA6 function by inhibiting DNA binding. Mol Cell Biol. 2005 Oct;25(20):8864-73 |
Lmna lamin A (Synonyms: Dhe, lamin A/C) | |
Results | Reference |
1 | J:311844 Landin MA, Nygard S, Shabestari MG, Babaie E, Reseland JE, Osmundsen H, Mapping the global mRNA transcriptome during development of the murine first molar. Front Genet. 2015;6:47 |
1 | J:252201 Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A, p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct;137(10):2157-2167 |
1* | J:289359 Rober RA, Weber K, Osborn M, Differential timing of nuclear lamin A/C expression in the various organs of the mouse embryo and the young animal: a developmental study. Development. 1989 Feb;105(2):365-78 |
1 | J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088 |
Lmnb1 lamin B1 | |
Results | Reference |
1 | J:264980 Coffinier C, Jung HJ, Nobumori C, Chang S, Tu Y, Barnes RH 2nd, Yoshinaga Y, de Jong PJ, Vergnes L, Reue K, Fong LG, Young SG, Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell. 2011 Dec;22(23):4683-93 |
1 | J:224310 Ishihara T, Ban-Ishihara R, Maeda M, Matsunaga Y, Ichimura A, Kyogoku S, Aoki H, Katada S, Nakada K, Nomura M, Mizushima N, Mihara K, Ishihara N, Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development. Mol Cell Biol. 2015 Jan;35(1):211-23 |
2 | J:252201 Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A, p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct;137(10):2157-2167 |
1 | J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088 |
1* | J:242348 Soh YQS, Mikedis MM, Kojima M, Godfrey AK, de Rooij DG, Page DC, Meioc maintains an extended meiotic prophase I in mice. PLoS Genet. 2017 Apr;13(4):e1006704 |
Lmnb2 lamin B2 (Synonyms: lamin B3) | |
Results | Reference |
1 | J:158610 Coffinier C, Chang SY, Nobumori C, Tu Y, Farber EA, Toth JI, Fong LG, Young SG, Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5076-81 |
1 | J:264980 Coffinier C, Jung HJ, Nobumori C, Chang S, Tu Y, Barnes RH 2nd, Yoshinaga Y, de Jong PJ, Vergnes L, Reue K, Fong LG, Young SG, Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell. 2011 Dec;22(23):4683-93 |
Lmo1 LIM domain only 1 (Synonyms: Rbtn-1, Rbtn1, Ttg1) | |
Results | Reference |
2* | J:15545 Boehm T, Spillantini MG, Sofroniew MV, Surani MA, Rabbitts TH, Developmentally regulated and tissue specific expression of mRNAs encoding the two alternative forms of the LIM domain oncogene rhombotin: evidence for thymus expression. Oncogene. 1991 May;6(5):695-703 |
1* | J:112338 Deng M, Pan L, Xie X, Gan L, Differential expression of LIM domain-only (LMO) genes in the developing mouse inner ear. Gene Expr Patterns. 2006 Dec;6(8):857-63 |
1 | J:327415 Jing J, Feng J, Yuan Y, Guo T, Lei J, Pei F, Ho TV, Chai Y, Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022 Aug 16;13(1):4803 |
Lmo3 LIM domain only 3 (Synonyms: Rbtn-3, Rbtn3) | |
Results | Reference |
1 | J:339096 Biswas S, Chan CS, Rubenstein JLR, Gan L, The transcription regulator Lmo3 is required for the development of medial ganglionic eminence derived neurons in the external globus pallidus. Dev Biol. 2023 Aug 1;503:10-24 |
1 | J:286655 Sakamoto S, Tateya T, Omori K, Kageyama R, Id genes are required for morphogenesis and cellular patterning in the developing mammalian cochlea. Dev Biol. 2020 Apr 15;460(2):164-175 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:304564 Venkataramanappa S, Schutz D, Saaber F, Kumar PA, Abe P, Schulz S, Stumm R, The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS Genet. 2021 Mar;17(3):e1009441 |
1 | J:86254 Vyas A, Saha B, Lai E, Tole S, Paleocortex is specified in mice in which dorsal telencephalic patterning is severely disrupted. J Comp Neurol. 2003 Nov 24;466(4):545-53 |
1 | J:319920 Ypsilanti AR, Pattabiraman K, Catta-Preta R, Golonzhka O, Lindtner S, Tang K, Jones IR, Abnousi A, Juric I, Hu M, Shen Y, Dickel DE, Visel A, Pennachio LA, Hawrylycz M, Thompson CL, Zeng H, Barozzi I, Nord AS, Rubenstein JL, Transcriptional network orchestrating regional patterning of cortical progenitors. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2024795118 |
Lmo4 LIM domain only 4 (Synonyms: A730077C12Rik, Crp3, Etohi4) | |
Results | Reference |
1 | J:215675 Deng M, Luo XJ, Pan L, Yang H, Xie X, Liang G, Huang L, Hu F, Kiernan AE, Gan L, LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea. J Neurosci. 2014 Jul 23;34(30):10072-7 |
1 | J:166059 Duquette PM, Zhou X, Yap NL, MacLaren EJ, Lu JJ, Wallace VA, Chen HH, Loss of LMO4 in the retina leads to reduction of GABAergic amacrine cells and functional deficits. PLoS One. 2010;5(10):e13232 |
1* | J:52152 Grutz G, Forster A, Rabbitts TH, Identification of the LMO4 gene encoding an interaction partner of the LIM-binding protein LDB1/NLI1: a candidate for displacement by LMO proteins in T cell acute leukaemia. Oncogene. 1998 Nov 26;17(21):2799-803 |
1* | J:88168 Hahm K, Sum EY, Fujiwara Y, Lindeman GJ, Visvader JE, Orkin SH, Defective neural tube closure and anteroposterior patterning in mice lacking the LIM protein LMO4 or its interacting partner Deaf-1. Mol Cell Biol. 2004 Mar;24(5):2074-82 |
1 | J:230652 Harb K, Magrinelli E, Nicolas CS, Lukianets N, Frangeul L, Pietri M, Sun T, Sandoz G, Grammont F, Jabaudon D, Studer M, Alfano C, Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications. Elife. 2016;5:e09531 |
2* | J:138857 Hislop NR, Caddy J, Ting SB, Auden A, Vasudevan S, King SL, Lindeman GJ, Visvader JE, Cunningham JM, Jane SM, Grhl3 and Lmo4 play coordinate roles in epidermal migration. Dev Biol. 2008 Sep 1;321(1):263-72 |
1 | J:262601 Huang Y, Hill J, Yatteau A, Wong L, Jiang T, Petrovic J, Gan L, Dong L, Wu DK, Reciprocal Negative Regulation Between Lmx1a and Lmo4 Is Required for Inner Ear Formation. J Neurosci. 2018 Jun 6;38(23):5429-5440 |
1 | J:286655 Sakamoto S, Tateya T, Omori K, Kageyama R, Id genes are required for morphogenesis and cellular patterning in the developing mammalian cochlea. Dev Biol. 2020 Apr 15;460(2):164-175 |
2* | J:98098 Sum EY, O'Reilly LA, Jonas N, Lindeman GJ, Visvader JE, The LIM domain protein Lmo4 is highly expressed in proliferating mouse epithelial tissues. J Histochem Cytochem. 2005 Apr;53(4):475-86 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Lmo7 LIM domain only 7 (Synonyms: FBXO20, LOC380928, mKIAA0858) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Lmod3 leiomodin 3 (fetal) (Synonyms: 5430424A14Rik) | |
Results | Reference |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
Lmx1a LIM homeobox transcription factor 1 alpha (Synonyms: Lmx1.1, shaker short-tail) | |
Results | Reference |
1* | J:161290 Chizhikov VV, Lindgren AG, Mishima Y, Roberts RW, Aldinger KA, Miesegaes GR, Currle DS, Monuki ES, Millen KJ, Lmx1a regulates fates and location of cells originating from the cerebellar rhombic lip and telencephalic cortical hem. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10725-30 |
1* | J:79521 Failli V, Bachy I, Retaux S, Expression of the LIM-homeodomain gene Lmx1a (dreher) during development of the mouse nervous system. Mech Dev. 2002 Oct;118(1-2):225 |
1 | J:262601 Huang Y, Hill J, Yatteau A, Wong L, Jiang T, Petrovic J, Gan L, Dong L, Wu DK, Reciprocal Negative Regulation Between Lmx1a and Lmo4 Is Required for Inner Ear Formation. J Neurosci. 2018 Jun 6;38(23):5429-5440 |
1 | J:222854 Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen JK, Gomez-Galan M, Sopova E, Joodmardi E, Yoshitake T, Deng Q, Kehr J, Ericson J, Svenningsson P, Shupliakov O, Perlmann T, Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease. Nat Neurosci. 2015 Jun;18(6):826-35 |
1* | J:199301 Lavado A, He Y, Pare J, Neale G, Olson EN, Giovannini M, Cao X, Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34 |
1* | J:353281 Rybiczka-Tesulov M, Garritsen O, Veno MT, Wieg L, Dijk RV, Rahimi K, Gomes-Duarte A, Wit M, van de Haar LL, Michels L, van Kronenburg NCH, van der Meer C, Kjems J, Vangoor VR, Pasterkamp RJ, Circular RNAs regulate neuron size and migration of midbrain dopamine neurons during development. Nat Commun. 2024 Aug 8;15(1):6773 |
1 | J:286655 Sakamoto S, Tateya T, Omori K, Kageyama R, Id genes are required for morphogenesis and cellular patterning in the developing mammalian cochlea. Dev Biol. 2020 Apr 15;460(2):164-175 |
1 | J:270726 Shimada IS, Hwang SH, Somatilaka BN, Wang X, Skowron P, Kim J, Kim M, Shelton JM, Rajaram V, Xuan Z, Taylor MD, Mukhopadhyay S, Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis. Cell Rep. 2018 Jan 30;22(5):1169-1184 |
Lmx1b LIM homeobox transcription factor 1 beta (Synonyms: GENA 191, Icst, LMX1.2) | |
Results | Reference |
1 | J:80942 Asbreuk CH, Vogelaar CF, Hellemons A, Smidt MP, Burbach JP, CNS expression pattern of lmx1b and coexpression with ptx genes suggest functional cooperativity in the development of forebrain motor control systems. Mol Cell Neurosci. 2002 Nov;21(3):410-20 |
1* | J:352627 Baltar J, Miranda RM, Cabral M, Rebelo S, Grahammer F, Huber TB, Reguenga C, Monteiro FA, Neph1 is required for neurite branching and is negatively regulated by the PRRXL1 homeodomain factor in the developing spinal cord dorsal horn. Neural Dev. 2024 Jul 24;19(1):13 |
1* | J:267540 Cesario JM, Landin Malt A, Chung JU, Khairallah MP, Dasgupta K, Asam K, Deacon LJ, Choi V, Almaidhan AA, Darwiche NA, Kim J, Johnson RL, Jeong J, Anti-osteogenic function of a LIM-homeodomain transcription factor LMX1B is essential to early patterning of the calvaria. Dev Biol. 2018 Nov 15;443(2):103-116 |
1 | J:113891 Dreyer SD, Morello R, German MS, Zabel B, Winterpacht A, Lunstrum GP, Horton WA, Oberg KC, Lee B, LMX1B transactivation and expression in nail-patella syndrome. Hum Mol Genet. 2000 Apr 12;9(7):1067-74 |
1* | J:90613 Dreyer SD, Naruse T, Morello R, Zabel B, Winterpacht A, Johnson RL, Lee B, Oberg KC, Lmx1b expression during joint and tendon formation: localization and evaluation of potential downstream targets. Gene Expr Patterns. 2004 Jul;4(4):397-405 |
1 | J:184011 John A, Brylka H, Wiegreffe C, Simon R, Liu P, Juttner R, Crenshaw EB 3rd, Luyten FP, Jenkins NA, Copeland NG, Birchmeier C, Britsch S, Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. Development. 2012 May;139(10):1831-41 |
1* | J:331872 Johnson GL, Glasser MB, Charles JF, Duryea J, Lehoczky JA, En1 and Lmx1b do not recapitulate embryonic dorsal-ventral limb patterning functions during mouse digit tip regeneration. Cell Rep. 2022 Nov 22;41(8):111701 |
1 | J:222854 Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen JK, Gomez-Galan M, Sopova E, Joodmardi E, Yoshitake T, Deng Q, Kehr J, Ericson J, Svenningsson P, Shupliakov O, Perlmann T, Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease. Nat Neurosci. 2015 Jun;18(6):826-35 |
1 | J:201154 Meziane H, Fraulob V, Riet F, Krezel W, Selloum M, Geffarth M, Acampora D, Herault Y, Simeone A, Brand M, Dolle P, Rhinn M, The homeodomain factor Gbx1 is required for locomotion and cell specification in the dorsal spinal cord. PeerJ. 2013;1:e142 |
1 | J:124270 Ono Y, Nakatani T, Sakamoto Y, Mizuhara E, Minaki Y, Kumai M, Hamaguchi A, Nishimura M, Inoue Y, Hayashi H, Takahashi J, Imai T, Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells. Development. 2007 Sep;134(17):3213-25 |
1* | J:160590 Rebelo S, Reguenga C, Lopes C, Lima D, Prrxl1 is required for the generation of a subset of nociceptive glutamatergic superficial spinal dorsal horn neurons. Dev Dyn. 2010 Jun;239(6):1684-94 |
1 | J:124186 Rebelo S, Reguenga C, Osorio L, Pereira C, Lopes C, Lima D, DRG11 immunohistochemical expression during embryonic development in the mouse. Dev Dyn. 2007 Sep;236(9):2653-60 |
1 | J:165741 Rojas A, Schachterle W, Xu SM, Martin F, Black BL, Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer. Dev Biol. 2010 Oct 15;346(2):346-55 |
1 | J:287023 Schnerwitzki D, Perry S, Ivanova A, Caixeta FV, Cramer P, Gunther S, Weber K, Tafreshiha A, Becker L, Vargas Panesso IL, Klopstock T, Hrabe de Angelis M, Schmidt M, Kullander K, Englert C, Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord. Life Sci Alliance. 2018 Aug;1(4):e201800106 |
1 | J:116148 Stolt CC, Schlierf A, Lommes P, Hillgartner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M, SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell. 2006 Nov;11(5):697-709 |
1* | J:116706 Zhao ZQ, Scott M, Chiechio S, Wang JS, Renner KJ, Gereau RW 4th, Johnson RL, Deneris ES, Chen ZF, Lmx1b is required for maintenance of central serotonergic neurons and mice lacking central serotonergic system exhibit normal locomotor activity. J Neurosci. 2006 Dec 6;26(49):12781-8 |
Lncbar BAF chromatin remodeling complex associated lncRNA | |
Results | Reference |
1* | J:316179 Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y, An epigenetic circuit controls neurogenic programs during neocortex development. Development. 2021;148:dev199772 |
Lnpk lunapark, ER junction formation factor (Synonyms: 2310011O18Rik, 4921514L11Rik, 9530051D01Rik, Lnp, Lnpk1, lunapark) | |
Results | Reference |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1* | J:269239 Breuss MW, Nguyen A, Song Q, Nguyen T, Stanley V, James KN, Musaev D, Chai G, Wirth SA, Anzenberg P, George RD, Johansen A, Ali S, Zia-Ur-Rehman M, Sultan T, Zaki MS, Gleeson JG, Mutations in LNPK, Encoding the Endoplasmic Reticulum Junction Stabilizer Lunapark, Cause a Recessive Neurodevelopmental Syndrome. Am J Hum Genet. 2018 Aug 2;103(2):296-304 |
Lnx2 ligand of numb-protein X 2 | |
Results | Reference |
2* | J:100943 Mirza M, Raschperger E, Philipson L, Pettersson RF, Sollerbrant K, The cell surface protein coxsackie- and adenovirus receptor (CAR) directly associates with the Ligand-of-Numb Protein-X2 (LNX2). Exp Cell Res. 2005 Sep 10;309(1):110-20 |
Loricrin loricrin cornified envelope precursor protein | |
Results | Reference |
1 | J:233601 Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP, Harwood CA, Byrne C, O'Shaughnessy RF, Bergamaschi D, Constitutive Autophagy and Nucleophagy during Epidermal Differentiation. J Invest Dermatol. 2016 Jul;136(7):1460-70 |
1* | J:20591 Byrne C, Tainsky M, Fuchs E, Programming gene expression in developing epidermis. Development. 1994 Sep;120(9):2369-83 |
1 | J:299752 Cottle DL, Ursino GMA, Jones LK, Tham MS, Zylberberg AK, Smyth IM, Topical Aminosalicylic Acid Improves Keratinocyte Differentiation in an Inducible Mouse Model of Harlequin Ichthyosis. Cell Rep Med. 2020 Nov 17;1(8):100129 |
1* | J:129949 Cui CY, Kunisada M, Esibizione D, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet. 2007 Nov 1;16(21):2583-90 |
1 | J:207252 Drosten M, Lechuga CG, Barbacid M, Ras signaling is essential for skin development. Oncogene. 2014 May 29;33(22):2857-65 |
1 | J:260456 Duteil D, Tourrette Y, Eberlin A, Willmann D, Patel D, Friedrichs N, Muller JM, Schule R, The histone acetyltransferase inhibitor Nir regulates epidermis development. Development. 2018 Mar 21;145(6):dev158543 |
1 | J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39 |
2 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
2 | J:83259 Jaubert J, Cheng J, Segre JA, Ectopic expression of kruppel like factor 4 (Klf4) accelerates formation of the epidermal permeability barrier. Development. 2003 Jun;130(12):2767-77 |
1 | J:135131 Kashiwagi M, Morgan BA, Georgopoulos K, The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny. Development. 2007 Apr;134(8):1571-82 |
1* | J:51300 Keeney DS, Skinner C, Travers JB, Capdevila JH, Nanney LB, King LE Jr, Waterman MR, Differentiating keratinocytes express a novel cytochrome P450 enzyme, CYP2B19, having arachidonate monooxygenase activity. J Biol Chem. 1998 Nov 27;273(48):32071-9 |
1 | J:261926 Kwon E, Todorova K, Wang J, Horos R, Lee KK, Neel VA, Negri GL, Sorensen PH, Lee SW, Hentze MW, Mandinova A, The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level. Nat Commun. 2018 Apr 30;9(1):1734 |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
1 | J:213415 Lee B, Villarreal-Ponce A, Fallahi M, Ovadia J, Sun P, Yu QC, Ito S, Sinha S, Nie Q, Dai X, Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells. Dev Cell. 2014 Apr 14;29(1):47-58 |
1 | J:352165 Lin Y, Tang W, Huang P, Wang Z, Duan L, Jia C, Sun R, Liu L, Shen J, Denticleless E3 ubiquitin protein ligase (DTL) maintains the proliferation and differentiation of epidermis and hair follicles during skin development. Dev Dyn. 2024 Jul;253(7):635-647 |
1 | J:206588 Mardaryev AN, Gdula MR, Yarker JL, Emelianov VN, Poterlowicz K, Sharov AA, Sharova TY, Scarpa JA, Chambon P, Botchkarev VA, Fessing MY, p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells. Development. 2014 Jan;141(1):101-11 |
1 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
1 | J:210514 Martinez P, Ferrara-Romeo I, Flores JM, Blasco MA, Essential role for the TRF2 telomere protein in adult skin homeostasis. Aging Cell. 2014 Aug;13(4):656-68 |
1 | J:175603 Mejetta S, Morey L, Pascual G, Kuebler B, Mysliwiec MR, Lee Y, Shiekhattar R, Di Croce L, Benitah SA, Jarid2 regulates mouse epidermal stem cell activation and differentiation. EMBO J. 2011;30(17):3635-46 |
1 | J:279389 Miao Q, Hill MC, Chen F, Mo Q, Ku AT, Ramos C, Sock E, Lefebvre V, Nguyen H, SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair. Nat Commun. 2019 Sep 6;10(1):4042 |
1* | J:234993 Nishiguchi Y, Ohmoto M, Koki J, Enomoto T, Kominami R, Matsumoto I, Hirota J, Bcl11b/Ctip2 is required for development of lingual papillae in mice. Dev Biol. 2016 Aug 1;416(1):98-110 |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
1 | J:309456 Pearson HB, McGlinn E, Phesse TJ, Schluter H, Srikumar A, Godde NJ, Woelwer CB, Ryan A, Phillips WA, Ernst M, Kaur P, Humbert P, The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis. Mol Cancer. 2015 Sep 17;14:169 |
1 | J:144194 Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72 |
2* | J:48444 Takaishi M, Takata Y, Kuroki T, Huh N, Isolation and characterization of a putative keratin-associated protein gene expressed in embryonic skin of mice. J Invest Dermatol. 1998 Jul;111(1):128-32 |
1 | J:196491 Torchia EC, Zhang L, Huebner AJ, Sen S, Roop DR, Aurora kinase-A deficiency during skin development impairs cell division and stratification. J Invest Dermatol. 2013 Jan;133(1):78-86 |
1* | J:117802 Troy TC, Li Y, O'malley L, Turksen K, The temporal and spatial expression of Claudins in epidermal development and the accelerated program of epidermal differentiation in K14-CaSR transgenic mice. Gene Expr Patterns. 2007 Feb;7(4):423-30 |
1 | J:338452 Wang D, Li H, Chandel NS, Dou Y, Yi R, MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters. Nat Commun. 2023 Jul 21;14(1):4404 |
1 | J:169856 Xin Y, Lu Q, Li Q, IKK1 Control of Epidermal Differentiation Is Modulated by Notch Signaling. Am J Pathol. 2011 Apr;178(4):1568-77 |
1 | J:114626 Yu Z, Lin KK, Bhandari A, Spencer JA, Xu X, Wang N, Lu Z, Gill GN, Roop DR, Wertz P, Andersen B, The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Dev Biol. 2006 Nov 1;299(1):122-36 |
1 | J:146244 Zuklys S, Gill J, Keller MP, Hauri-Hohl M, Zhanybekova S, Balciunaite G, Na KJ, Jeker LT, Hafen K, Tsukamoto N, Amagai T, Taketo MM, Krenger W, Hollander GA, Stabilized beta-catenin in thymic epithelial cells blocks thymus development and function. J Immunol. 2009 Mar 1;182(5):2997-3007 |
Lox lysyl oxidase (Synonyms: ras recision gene (rrg), TSC-160) | |
Results | Reference |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
Loxhd1 lipoxygenase homology domains 1 (Synonyms: 1700096C21Rik, sba) | |
Results | Reference |
1 | J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12) |
Loxl1 lysyl oxidase-like 1 (Synonyms: LOXL) | |
Results | Reference |
1 | J:96844 Hayashi K, Fong KS, Mercier F, Boyd CD, Csiszar K, Hayashi M, Comparative immunocytochemical localization of lysyl oxidase (LOX) and the lysyl oxidase-like (LOXL) proteins: changes in the expression of LOXL during development and growth of mouse tissues. J Mol Histol. 2004 Nov;35(8-9):845-55 |
Loxl3 lysyl oxidase-like 3 (Synonyms: Lor2) | |
Results | Reference |
1 | J:307861 Yaseen W, Kraft-Sheleg O, Zaffryar-Eilot S, Melamed S, Sun C, Millay DP, Hasson P, Fibroblast fusion to the muscle fiber regulates myotendinous junction formation. Nat Commun. 2021 Jun 22;12(1):3852 |
1* | J:226416 Zhang J, Yang R, Liu Z, Hou C, Zong W, Zhang A, Sun X, Gao J, Loss of lysyl oxidase-like 3 causes cleft palate and spinal deformity in mice. Hum Mol Genet. 2015 Nov 1;24(21):6174-85 |
Lpar1 lysophosphatidic acid receptor 1 (Synonyms: Edg2, Gpcr26, Kdt2, LPA1, vzg-1) | |
Results | Reference |
1 | J:302131 Hu HB, Song ZQ, Song GP, Li S, Tu HQ, Wu M, Zhang YC, Yuan JF, Li TT, Li PY, Xu YL, Shen XL, Han QY, Li AL, Zhou T, Chun J, Zhang XM, Li HY, LPA signaling acts as a cell-extrinsic mechanism to initiate cilia disassembly and promote neurogenesis. Nat Commun. 2021 Jan 28;12(1):662 |
1* | J:321064 Kim NH, Sadra A, Park HY, Oh SM, Chun J, Yoon JK, Huh SO, HeLa E-Box Binding Protein, HEB, Inhibits Promoter Activity of the Lysophosphatidic Acid Receptor Gene Lpar1 in Neocortical Neuroblast Cells. Mol Cells. 2019 Feb 28;42(2):123-134 |
Lpcat1 lysophosphatidylcholine acyltransferase 1 (Synonyms: 2900035H07Rik, Aytl2, LPCAT, MGC:8148, rd11) | |
Results | Reference |
1 | J:180979 Besnard V, Wert SE, Ikegami M, Xu Y, Heffner C, Murray SA, Donahue LR, Whitsett JA, Maternal synchronization of gestational length and lung maturation. PLoS One. 2011;6(11):e26682 |
1* | J:111827 Chen X, Hyatt BA, Mucenski ML, Mason RJ, Shannon JM, Identification and characterization of a lysophosphatidylcholine acyltransferase in alveolar type II cells. Proc Natl Acad Sci U S A. 2006 Aug 1;103(31):11724-9 |
2 | J:224542 Gao L, Rabbitt EH, Condon JC, Renthal NE, Johnston JM, Mitsche MA, Chambon P, Xu J, O'Malley BW, Mendelson CR, Steroid receptor coactivators 1 and 2 mediate fetal-to-maternal signaling that initiates parturition. J Clin Invest. 2015 Jul 1;125(7):2808-24 |
2 | J:237343 Laresgoiti U, Nikolic MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL, Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016 Oct 15;143(20):3686-3699 |
1* | J:310743 Lin S, Ikegami M, Moon C, Naren AP, Shannon JM, Lysophosphatidylcholine Acyltransferase 1 (LPCAT1) Specifically Interacts with Phospholipid Transfer Protein StarD10 to Facilitate Surfactant Phospholipid Trafficking in Alveolar Type II Cells. J Biol Chem. 2015 Jul 24;290(30):18559-74 |
Lpcat3 lysophosphatidylcholine acyltransferase 3 (Synonyms: Grcc3f, Mboat5, Oact5) | |
Results | Reference |
1* | J:229247 Hashidate-Yoshida T, Harayama T, Hishikawa D, Morimoto R, Hamano F, Tokuoka SM, Eto M, Tamura-Nakano M, Yanobu-Takanashi R, Mukumoto Y, Kiyonari H, Okamura T, Kita Y, Shindou H, Shimizu T, Fatty acid remodeling by LPCAT3 enriches arachidonate in phospholipid membranes and regulates triglyceride transport. Elife. 2015;4 |
Lpl lipoprotein lipase (Synonyms: O 1-4-5) | |
Results | Reference |
2* | J:166893 Cote M, Provost PR, Gerard-Hudon MC, Tremblay Y, Apolipoprotein C-II and lipoprotein lipase show a temporal and geographic correlation with surfactant lipid synthesis in preparation for birth. BMC Dev Biol. 2010;10:111 |
1* | J:145715 Provost PR, Boucher E, Tremblay Y, Apolipoprotein A-I, A-II, C-II, and H expression in the developing lung and sex difference in surfactant lipids. J Endocrinol. 2009 Mar;200(3):321-30 |
Lpo lactoperoxidase (Synonyms: 5830499B15Rik) | |
Results | Reference |
2 | J:341713 Aure MH, Symonds JM, Villapudua CU, Dodge JT, Werner S, Knosp WM, Hoffman MP, FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation. Nat Commun. 2023 Oct 14;14(1):6485 |
Lrat lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) (Synonyms: 1300010A18Rik) | |
Results | Reference |
1 | J:121381 Hu P, Zhang M, Napoli JL, Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal. Biochim Biophys Acta. 2007 Apr;1770(4):694-705 |
Lratd1 LRAT domain containing 1 (Synonyms: 2310003N02Rik, 4731402F03Rik, Fam84a) | |
Results | Reference |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
Lrfn1 leucine rich repeat and fibronectin type III domain containing 1 (Synonyms: MGC:7599, SALM2) | |
Results | Reference |
1* | J:112964 Morimura N, Inoue T, Katayama K, Aruga J, Comparative analysis of structure, expression and PSD95-binding capacity of Lrfn, a novel family of neuronal transmembrane proteins. Gene. 2006 Oct 1;380(2):72-83 |
Lrfn2 leucine rich repeat and fibronectin type III domain containing 2 (Synonyms: 5730420O05Rik, mKIAA1246, SALM1) | |
Results | Reference |
1* | J:112964 Morimura N, Inoue T, Katayama K, Aruga J, Comparative analysis of structure, expression and PSD95-binding capacity of Lrfn, a novel family of neuronal transmembrane proteins. Gene. 2006 Oct 1;380(2):72-83 |
Lrfn3 leucine rich repeat and fibronectin type III domain containing 3 (Synonyms: A530045B06Rik, SALM4) | |
Results | Reference |
1* | J:112964 Morimura N, Inoue T, Katayama K, Aruga J, Comparative analysis of structure, expression and PSD95-binding capacity of Lrfn, a novel family of neuronal transmembrane proteins. Gene. 2006 Oct 1;380(2):72-83 |
Lrfn4 leucine rich repeat and fibronectin type III domain containing 4 (Synonyms: MGC:36464, MGC:36545, SALM3) | |
Results | Reference |
1* | J:112964 Morimura N, Inoue T, Katayama K, Aruga J, Comparative analysis of structure, expression and PSD95-binding capacity of Lrfn, a novel family of neuronal transmembrane proteins. Gene. 2006 Oct 1;380(2):72-83 |
Lrfn5 leucine rich repeat and fibronectin type III domain containing 5 | |
Results | Reference |
1* | J:112964 Morimura N, Inoue T, Katayama K, Aruga J, Comparative analysis of structure, expression and PSD95-binding capacity of Lrfn, a novel family of neuronal transmembrane proteins. Gene. 2006 Oct 1;380(2):72-83 |
Lrig1 leucine-rich repeats and immunoglobulin-like domains 1 (Synonyms: Img, LIG-1) | |
Results | Reference |
1* | J:202451 Del Rio T, Nishitani AM, Yu WM, Goodrich LV, In vivo analysis of lrig genes reveals redundant and independent functions in the inner ear. PLoS Genet. 2013 Sep;9(9):e1003824 |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:306458 Jeong D, Lozano Casasbuenas D, Gengatharan A, Edwards K, Saghatelyan A, Kaplan DR, Miller FD, Yuzwa SA, LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex. Cell Rep. 2020 Oct 13;33(2):108257 |
2 | J:360633 Liu S, Li Y, Huang D, Liu M, Zhang X, Zhao H, Liu H, Li Q, Chen Z, Single-Cell RNA-Seq and Histological Analysis Reveals Dynamic Lrig1 Expression During Salivary Gland Development. J Cell Physiol. 2024 Nov 25; |
1 | J:321068 Maimets M, Pedersen MT, Guiu J, Dreier J, Thodberg M, Antoku Y, Schweiger PJ, Rib L, Bressan RB, Miao Y, Garcia KC, Sandelin A, Serup P, Jensen KB, Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling. Nat Commun. 2022 Feb 7;13(1):715 |
2 | J:227692 van Erp S, van den Heuvel DM, Fujita Y, Robinson RA, Hellemons AJ, Adolfs Y, Van Battum EY, Blokhuis AM, Kuijpers M, Demmers JA, Hedman H, Hoogenraad CC, Siebold C, Yamashita T, Pasterkamp RJ, Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases. Dev Cell. 2015 Dec 7;35(5):537-52 |
Lrig2 leucine-rich repeats and immunoglobulin-like domains 2 (Synonyms: 4632419I10Rik) | |
Results | Reference |
1* | J:202451 Del Rio T, Nishitani AM, Yu WM, Goodrich LV, In vivo analysis of lrig genes reveals redundant and independent functions in the inner ear. PLoS Genet. 2013 Sep;9(9):e1003824 |
2 | J:227692 van Erp S, van den Heuvel DM, Fujita Y, Robinson RA, Hellemons AJ, Adolfs Y, Van Battum EY, Blokhuis AM, Kuijpers M, Demmers JA, Hedman H, Hoogenraad CC, Siebold C, Yamashita T, Pasterkamp RJ, Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases. Dev Cell. 2015 Dec 7;35(5):537-52 |
Lrig3 leucine-rich repeats and immunoglobulin-like domains 3 (Synonyms: 9030421L11Rik, 9130004I02Rik, 9430095K15Rik, mKIAA3016) | |
Results | Reference |
2 | J:227692 van Erp S, van den Heuvel DM, Fujita Y, Robinson RA, Hellemons AJ, Adolfs Y, Van Battum EY, Blokhuis AM, Kuijpers M, Demmers JA, Hedman H, Hoogenraad CC, Siebold C, Yamashita T, Pasterkamp RJ, Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases. Dev Cell. 2015 Dec 7;35(5):537-52 |
Lrp1b low density lipoprotein-related protein 1B (Synonyms: 9630004P12Rik) | |
Results | Reference |
1* | J:329933 Akkuratova N, Faure L, Kameneva P, Kastriti ME, Adameyko I, Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics. Front Endocrinol (Lausanne). 2022;13:1020000 |
Lrp2 low density lipoprotein receptor-related protein 2 (Synonyms: b2b1625.2Clo, D230004K18Rik, Gp330, Megalin) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
2 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1* | J:150394 Jouret F, Auzanneau C, Debaix H, Wada GH, Pretto C, Marbaix E, Karet FE, Courtoy PJ, Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. J Am Soc Nephrol. 2005 Nov;16(11):3235-46 |
1* | J:199961 Lai SC, Nakayama Y, Sequeira JM, Wlodarczyk BJ, Cabrera RM, Finnell RH, Bottiglieri T, Quadros EV, The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system. FASEB J. 2013 Jun;27(6):2468-75 |
1 | J:306107 Niborski LL, Paces-Fessy M, Ricci P, Bourgeois A, Magalhaes P, Kuzma-Kuzniarska M, Lesaulnier C, Reczko M, Declercq E, Zurbig P, Doucet A, Umbhauer M, Cereghini S, Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model. Dis Model Mech. 2021 May 1;14(5):dmm047498 |
2 | J:183783 Ortega MC, Cases O, Merchan P, Kozyraki R, Clemente D, de Castro F, Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development. Glia. 2012 May;60(6):851-66 |
1* | J:151683 Parreira KS, Debaix H, Cnops Y, Geffers L, Devuyst O, Expression patterns of the aquaporin gene family during renal development: influence of genetic variability. Pflugers Arch. 2009 Aug;458(4):745-59 |
Lrp4 low density lipoprotein receptor-related protein 4 (Synonyms: 6430526J12Rik, mdig, Megf7) | |
Results | Reference |
1 | J:207796 Choi HY, Liu Y, Tennert C, Sugiura Y, Karakatsani A, Kroger S, Johnson EB, Hammer RE, Lin W, Herz J, APP interacts with LRP4 and agrin to coordinate the development of the neuromuscular junction in mice. Elife. 2013;2:e00220 |
1 | J:265947 Kawasaki M, Kawasaki K, Meguro F, Yamada A, Ishikawa R, Porntaveetus T, Blackburn J, Otsuka-Tanaka Y, Saito N, Ota MS, Sharpe PT, Kessler JA, Herz J, Cobourne MT, Maeda T, Ohazama A, Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms. PLoS One. 2018;13(9):e0204126 |
1 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1 | J:119654 Weatherbee SD, Anderson KV, Niswander LA, LDL-receptor-related protein 4 is crucial for formation of the neuromuscular junction. Development. 2006 Dec;133(24):4993-5000 |
1* | J:109159 Yamaguchi YL, Tanaka SS, Kasa M, Yasuda K, Tam PP, Matsui Y, Expression of low density lipoprotein receptor-related protein 4 (Lrp4) gene in the mouse germ cells. Gene Expr Patterns. 2006 Aug;6(6):607-612 |
Lrp5 low density lipoprotein receptor-related protein 5 (Synonyms: LR3, LRP7) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:143588 Kamiya N, Ye L, Kobayashi T, Mochida Y, Yamauchi M, Kronenberg HM, Feng JQ, Mishina Y, BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development. 2008 Nov;135(22):3801-11 |
1* | J:105879 Zhang TJ, Hoffman BG, Ruiz de Algara T, Helgason CD, SAGE reveals expression of Wnt signalling pathway members during mouse prostate development. Gene Expr Patterns. 2006 Mar;6(3):310-24 |
Lrp6 low density lipoprotein receptor-related protein 6
(Synonyms:
Cd, Gw, ska26, ska | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:353439 de Jaime-Soguero A, Hattemer J, Bufe A, Haas A, van den Berg J, van Batenburg V, Das B, di Marco B, Androulaki S, Bohly N, Landry JJM, Schoell B, Rosa VS, Villacorta L, Baskan Y, Trapp M, Benes V, Chabes A, Shahbazi M, Jauch A, Engel U, Patrizi A, Sotillo R, van Oudenaarden A, Bageritz J, Alfonso J, Bastians H, Acebron SP, Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress. Nat Commun. 2024 Aug 28;15(1):7404 |
1 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
1 | J:313300 Mesman S, van Hooft JA, Smidt MP, Mest/Peg1 Is Essential for the Development and Maintenance of a SNc Neuronal Subset. Front Mol Neurosci. 2016;9:166 |
1 | J:237499 Sima J, Piao Y, Chen Y, Schlessinger D, Molecular dynamics of Dkk4 modulates Wnt action and regulates meibomian gland development. Development. 2016 Dec 15;143(24):4723-4735 |
Lrp8 low density lipoprotein receptor-related protein 8, apolipoprotein e receptor (Synonyms: 4932703M08Rik, apoER2, Lr8b) | |
Results | Reference |
1 | J:109820 Arnaud L, Ballif BA, Forster E, Cooper JA, Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development. Curr Biol. 2003 Jan 8;13(1):9-17 |
1 | J:126335 Hack I, Hellwig S, Junghans D, Brunne B, Bock HH, Zhao S, Frotscher M, Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons. Development. 2007 Nov;134(21):3883-91 |
1 | J:219839 Hirota Y, Kubo K, Katayama K, Honda T, Fujino T, Yamamoto TT, Nakajima K, Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex. J Comp Neurol. 2015 Feb 15;523(3):463-78 |
1 | J:299731 Kohno T, Ishii K, Hirota Y, Honda T, Makino M, Kawasaki T, Nakajima K, Hattori M, Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner. J Neurosci. 2020 Oct 21;40(43):8248-8261 |
1* | J:82121 Luque JM, Morante-Oria J, Fairen A, Localization of ApoER2, VLDLR and Dab1 in radial glia: groundwork for a new model of reelin action during cortical development. Brain Res Dev Brain Res. 2003 Feb 16;140(2):195-203 |
1 | J:171375 Senturk A, Pfennig S, Weiss A, Burk K, Acker-Palmer A, Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration. Nature. 2011 Apr 21;472(7343):356-60 |
Lrp11 low density lipoprotein receptor-related protein 11 (Synonyms: 1700034J19Rik, 9830160H19Rik) | |
Results | Reference |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
Lrpap1 low density lipoprotein receptor-related protein associated protein 1 (Synonyms: RAP) | |
Results | Reference |
1 | J:281878 Yook C, Kim K, Kim D, Kang H, Kim SG, Kim E, Kim SY, A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice. Front Mol Neurosci. 2019;12:241 |
Lrrc8a leucine rich repeat containing 8A VRAC subunit A (Synonyms: ebo, Lrrc8, mKIAA1437, SWELL1) | |
Results | Reference |
1* | J:319765 Chen L, Chen Y, Xu Y, Shen SG, Dai J, Effect of Swell1 on regulating chondrocyte hypertrophy during the condylar osteochondral development process in mice. Biochem Biophys Res Commun. 2022 Jan 29;590:42-48 |
Lrrc10 leucine rich repeat containing 10 (Synonyms: D330003I11Rik, Hrlrrp, Serdin1) | |
Results | Reference |
1* | J:123320 Kim KH, Kim TG, Micales BK, Lyons GE, Lee Y, Dynamic expression patterns of leucine-rich repeat containing protein 10 in the heart. Dev Dyn. 2007 Aug;236(8):2225-34 |
Lrrc23 leucine rich repeat containing 23 (Synonyms: 4921537K05Rik, Lrpb7) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Lrrc32 leucine rich repeat containing 32 (Synonyms: D11S833Eh, D7H11S833E, EG434215, Garp) | |
Results | Reference |
2* | J:34993 Roubin R, Pizette S, Ollendorff V, Planche J, Birnbaum D, Delapeyriere O, Structure and developmental expression of mouse Garp, a gene encoding a new leucine-rich repeat-containing protein. Int J Dev Biol. 1996 Jun;40(3):545-55 |
Lrrc51 leucine rich repeat containing 51 (Synonyms: 1700008D07Rik, Lrtomt) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Lrrk1 leucine-rich repeat kinase 1 (Synonyms: C230002E15Rik, D130026O16Rik, mKIAA1790) | |
Results | Reference |
1* | J:161970 Zechel S, Meinhardt A, Unsicker K, von Bohlen Und Halbach O, Expression of leucine-rich-repeat-kinase 2 (LRRK2) during embryonic development. Int J Dev Neurosci. 2010 Aug;28(5):391-9 |
Lrrk2 leucine-rich repeat kinase 2 (Synonyms: 4921513O20Rik, 9330188B09Rik, cI-46, D630001M17Rik, LOC381026) | |
Results | Reference |
1* | J:161970 Zechel S, Meinhardt A, Unsicker K, von Bohlen Und Halbach O, Expression of leucine-rich-repeat-kinase 2 (LRRK2) during embryonic development. Int J Dev Neurosci. 2010 Aug;28(5):391-9 |
Lrrn1 leucine rich repeat protein 1, neuronal (Synonyms: 2810047E21Rik, NLRR-1) | |
Results | Reference |
2 | J:344891 Maunsell HR, Ellis K, Kelley MW, Driver EC, Lrrn1 Regulates Medial Boundary Formation in the Developing Mouse Organ of Corti. J Neurosci. 2023 Jul 19;43(29):5305-5318 |
1 | J:267715 Wiwatpanit T, Lorenzen SM, Cantu JA, Foo CZ, Hogan AK, Marquez F, Clancy JC, Schipma MJ, Cheatham MA, Duggan A, Garcia-Anoveros J, Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1. Nature. 2018 Nov;563(7733):691-695 |
Lrrn3 leucine rich repeat protein 3, neuronal (Synonyms: NLRR-3) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Lrtm2 leucine-rich repeats and transmembrane domains 2 | |
Results | Reference |
1 | J:325069 Ichise M, Sakoori K, Katayama KI, Morimura N, Yamada K, Ozawa H, Matsunaga H, Hatayama M, Aruga J, Leucine-Rich Repeats and Transmembrane Domain 2 Controls Protein Sorting in the Striatal Projection System and Its Deficiency Causes Disturbances in Motor Responses and Monoamine Dynamics. Front Mol Neurosci. 2022;15:856315 |
Lsamp limbic system-associated membrane protein (Synonyms: B130007O04Rik, D930023J12Rik, Lam, Lamp) | |
Results | Reference |
1* | J:312430 Fearnley S, Raja R, Cloutier JF, Spatiotemporal expression of IgLON family members in the developing mouse nervous system. Sci Rep. 2021 Oct 1;11(1):19536 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Lsm4 LSM4 homolog, U6 small nuclear RNA and mRNA degradation associated | |
Results | Reference |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Lsm14b LSM family member 14B | |
Results | Reference |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
Lsp1 lymphocyte specific 1 (Synonyms: leukocyte specific protein 1, leukocyte-specific protein 1, Lsp-1, lymphocyte-specific protein 1, p50, pp52, WP34) | |
Results | Reference |
2* | J:22171 Misener VL, Hui C, Malapitan IA, Ittel ME, Joyner AL, Jongstra J, Expression of mouse LSP1/S37 isoforms. S37 is expressed in embryonic mesenchymal cells. J Cell Sci. 1994 Dec;107(Pt 12):3591-600 |
Lta lymphotoxin A (Synonyms: hlb382, LT, LT-[a], LT[a], LT-alpha, LTalpha, Ltx, lymphotoxin, lymphotoxin alpha, Tnfb, TNF beta, TNF-beta, Tnfsf1b) | |
Results | Reference |
1* | J:44503 Montgomery RA, Dallman MJ, Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny. Cytokine. 1997 Oct;9(10):717-26 |
1* | J:55762 Montgomery RA, Dallman MJ, Analysis of cytokine gene expression during fetal thymic ontogeny using the polymerase chain reaction. J Immunol. 1991 Jul 15;147(2):554-60 |
1 | J:53267 Yokota Y, Mansouri A, Mori S, Sugawara S, Adachi S, Nishikawa S, Gruss P, Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature. 1999 Feb 25;397(6721):702-6 |
Ltb lymphotoxin B (Synonyms: LTbeta, lymphotoxin beta, p33, Tnfc, Tnfsf3) | |
Results | Reference |
1 | J:76418 Browning JL, French LE, Visualization of Lymphotoxin-beta and Lymphotoxin-beta Receptor Expression in Mouse Embryos. J Immunol. 2002 May 15;168(10):5079-87 |
1 | J:111051 Cui CY, Hashimoto T, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9142-7 |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
1 | J:53267 Yokota Y, Mansouri A, Mori S, Sugawara S, Adachi S, Nishikawa S, Gruss P, Development of peripheral lymphoid organs and natural killer cells depends on the helix-loop-helix inhibitor Id2. Nature. 1999 Feb 25;397(6721):702-6 |
Ltbp1 latent transforming growth factor beta binding protein 1 (Synonyms: 9430031G15Rik, b2b1000Clo, LTBP-1, Ltbp1L) | |
Results | Reference |
1* | J:228706 Chandramouli A, Simundza J, Pinderhughes A, Hiremath M, Droguett G, Frendewey D, Cowin P, Ltbp1L is focally induced in embryonic mammary mesenchyme, demarcates the ductal luminal lineage and is upregulated during involution. Breast Cancer Res. 2013;15(6):R111 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Ltbp2 latent transforming growth factor beta binding protein 2 | |
Results | Reference |
2* | J:44707 Fang J, Li X, Smiley E, Francke U, Mecham RP, Bonadio J, Mouse latent TGF-beta binding protein-2: molecular cloning and developmental expression. Biochim Biophys Acta. 1997 Nov 20;1354(3):219-30 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
Ltbp3 latent transforming growth factor beta binding protein 3 (Synonyms: Ltbp2) | |
Results | Reference |
1 | J:79920 Dabovic B, Chen Y, Colarossi C, Zambuto L, Obata H, Rifkin DB, Bone defects in latent TGF-beta binding protein (Ltbp)-3 null mice; a role for Ltbp in TGF-beta presentation. J Endocrinol. 2002 Oct;175(1):129-41 |
1* | J:220985 Huckert M, Stoetzel C, Morkmued S, Laugel-Haushalter V, Geoffroy V, Muller J, Clauss F, Prasad MK, Obry F, Raymond JL, Switala M, Alembik Y, Soskin S, Mathieu E, Hemmerle J, Weickert JL, Dabovic BB, Rifkin DB, Dheedene A, Boudin E, Caluseriu O, Cholette MC, Mcleod R, Antequera R, Gelle MP, Coeuriot JL, Jacquelin LF, Bailleul-Forestier I, Maniere MC, Van Hul W, Bertola D, Dolle P, Verloes A, Mortier G, Dollfus H, Bloch-Zupan A, Mutations in the latent TGF-beta binding protein 3 (LTBP3) gene cause brachyolmia with amelogenesis imperfecta. Hum Mol Genet. 2015 Jun 1;24(11):3038-49 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:24946 Yin W, Smiley E, Germiller J, Mecham RP, Florer JB, Wenstrup RJ, Bonadio J, Isolation of a novel latent transforming growth factor-beta binding protein gene (LTBP-3). J Biol Chem. 1995 Apr 28;270(17):10147-60 |
Ltbr lymphotoxin B receptor (Synonyms: Ltar, LT beta-R, LTbetaR, LT-beta receptor, Tnfbr, TNFCR, TNFR2-RP, TNF receptor-related protein, TNF-R-III, TNFRrp, Tnfrsf3) | |
Results | Reference |
1 | J:76418 Browning JL, French LE, Visualization of Lymphotoxin-beta and Lymphotoxin-beta Receptor Expression in Mouse Embryos. J Immunol. 2002 May 15;168(10):5079-87 |
Ltf lactotransferrin (Synonyms: lactoferrin, Lf) | |
Results | Reference |
1* | J:54261 Ward PP, Mendoza-Meneses M, Mulac-Jericevic B, Cunningham GA, Saucedo-Cardenas O, Teng CT, Conneely OM, Restricted spatiotemporal expression of lactoferrin during murine embryonic development. Endocrinology. 1999 Apr;140(4):1852-60 |
Ltk leukocyte tyrosine kinase | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Lum lumican (Synonyms: Ldc, SLRR2D) | |
Results | Reference |
1 | J:175747 Liu W, Watson SS, Lan Y, Keene DR, Ovitt CE, Liu H, Schweitzer R, Jiang R, The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis. Mol Cell Biol. 2010 Oct;30(20):4797-807 |
2* | J:73681 Saika S, Saika S, Liu CY, Azhar M, Sanford LP, Doetschman T, Gendron RL, Kao CW, Kao WW, TGFbeta2 in corneal morphogenesis during mouse embryonic development. Dev Biol. 2001 Dec 15;240(2):419-32 |
1 | J:125580 Zhang L, Deng M, Kao CW, Kao WW, Xia Y, MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis. Mol Vis. 2003 Nov 3;9:584-93 |
Luzp1 leucine zipper protein 1 (Synonyms: 2700072H04Rik, Luzp) | |
Results | Reference |
1* | J:141306 Hsu CY, Chang NC, Lee MW, Lee KH, Sun DS, Lai C, Chang AC, LUZP deficiency affects neural tube closure during brain development. Biochem Biophys Res Commun. 2008 Nov 21;376(3):466-71 |
Lvrn laeverin (Synonyms: 4833403I15Rik, Aqpep) | |
Results | Reference |
1* | J:277364 Tobita T, Kiyozumi D, Muto M, Noda T, Ikawa M, Lvrn expression is not critical for mouse placentation. J Reprod Dev. 2019 Jun 14;65(3):239-244 |
Lxn latexin | |
Results | Reference |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
Ly6a lymphocyte antigen 6 family member A (Synonyms: Ly-6A.2, Ly-6A/E, Ly-6E.1, Sca-1, Sca1, TAP) | |
Results | Reference |
1 | J:359797 Coren L, Zaffryar-Eilot S, Odeh A, Kaganovsky A, Hasson P, Fibroblast diversification is an embryonic process dependent on muscle contraction. Cell Rep. 2024 Dec 4;43(12):115034 |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:362521 Guo XL, Wang YD, Liu YJ, Chu L, Zhu H, Hu Y, Wu RY, Xie HY, Yu J, Li SP, Xiong CY, Li RY, Ke F, Chen L, Chen GQ, Chen L, Bai F, Enver T, Li GH, Li HF, Hong DL, Fetal hepatocytes protect the HSPC genome via fetuin-A. Nature. 2025 Jan;637(8045):402-411 |
1 | J:165655 Kieslinger M, Hiechinger S, Dobreva G, Consalez GG, Grosschedl R, Early B cell factor 2 regulates hematopoietic stem cell homeostasis in a cell-nonautonomous manner. Cell Stem Cell. 2010 Oct 8;7(4):496-507 |
1 | J:271268 Yui S, Azzolin L, Maimets M, Pedersen MT, Fordham RP, Hansen SL, Larsen HL, Guiu J, Alves MRP, Rundsten CF, Johansen JV, Li Y, Madsen CD, Nakamura T, Watanabe M, Nielsen OH, Schweiger PJ, Piccolo S, Jensen KB, YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration. Cell Stem Cell. 2018 Jan 4;22(1):35-49.e7 |
Ly6c1 lymphocyte antigen 6 family member C1 (Synonyms: Ly6c, Ly-6C) | |
Results | Reference |
1 | J:359797 Coren L, Zaffryar-Eilot S, Odeh A, Kaganovsky A, Hasson P, Fibroblast diversification is an embryonic process dependent on muscle contraction. Cell Rep. 2024 Dec 4;43(12):115034 |
Ly6d lymphocyte antigen 6 family member D (Synonyms: Ly-61, Ly61, Thb) | |
Results | Reference |
1 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
Ly6e lymphocyte antigen 6 family member E (Synonyms: 9804, Ly67, RIG-E, Sca-2, Tsa1, TSA-1) | |
Results | Reference |
1* | J:253345 Bacquin A, Bireau C, Tanguy M, Romanet C, Vernochet C, Dupressoir A, Heidmann T, A Cell Fusion-Based Screening Method Identifies Glycosylphosphatidylinositol-Anchored Protein Ly6e as the Receptor for Mouse Endogenous Retroviral Envelope Syncytin-A. J Virol. 2017 Sep 15;91(18) |
1 | J:332508 Gao M, Liu X, Guo P, Wang J, Li J, Wang W, Stoddart MJ, Grad S, Li Z, Wu H, Li B, He Z, Zhou G, Liu S, Zhu W, Chen D, Zou X, Zhou Z, Deciphering postnatal limb development at single-cell resolution. iScience. 2023 Jan 20;26(1):105808 |
Ly75 lymphocyte antigen 75 (Synonyms: CD205, DEC-205) | |
Results | Reference |
1* | J:59927 Guerriero A, Langmuir PB, Spain LM, Scott EW, PU.1 is required for myeloid-derived but not lymphoid-derived dendritic cells. Blood. 2000 Feb 1;95(3):879-85 |
1 | J:290414 Li J, Gordon J, Chen ELY, Xiao S, Wu L, Zuniga-Pflucker JC, Manley NR, NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development. Development. 2020 Jun 22;147(12):dev178988 |
1 | J:291487 Liu D, Kousa AI, O'Neill KE, Rouse P, Popis M, Farley AM, Tomlinson SR, Ulyanchenko S, Guillemot F, Seymour PA, Jorgensen MC, Serup P, Koch U, Radtke F, Blackburn CC, Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development. Development. 2020 Jun 22;147(12):dev178582 |
Ly76 lymphocyte antigen 76 (Synonyms: Ter119, TER-119) | |
Results | Reference |
1 | J:227638 Alvarez S, Diaz M, Flach J, Rodriguez-Acebes S, Lopez-Contreras AJ, Martinez D, Canamero M, Fernandez-Capetillo O, Isern J, Passegue E, Mendez J, Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality. Nat Commun. 2015;6:8548 |
1* | J:330081 Chen S, Vedula RS, Cuevas-Navarro A, Lu B, Hogg SJ, Wang E, Benbarche S, Knorr K, Kim WJ, Stanley RF, Cho H, Erickson C, Singer M, Cui D, Tittley S, Durham BH, Pavletich TS, Fiala E, Walsh MF, Inoue D, Monette S, Taylor J, Rosen N, McCormick F, Lindsley RC, Castel P, Abdel-Wahab O, Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation. Cancer Discov. 2022 Oct 5;12(10):2434-2453 |
1 | J:294228 Kalailingam P, Wang KQ, Toh XR, Nguyen TQ, Chandrakanthan M, Hasan Z, Habib C, Schif A, Radio FC, Dallapiccola B, Weiss K, Nguyen LN, Deficiency of MFSD7c results in microcephaly-associated vasculopathy in Fowler syndrome. J Clin Invest. 2020 Aug 3;130(8):4081-4093 |
1 | J:342552 Kulikauskas MR, Oatley M, Yu T, Liu Z, Matsumura L, Kidder E, Ruter D, Bautch VL, Endothelial cell SMAD6 balances Alk1 function to regulate adherens junctions and hepatic vascular development. Development. 2023 Nov 1;150(21) |
1 | J:160267 Uhrin P, Zaujec J, Breuss JM, Olcaydu D, Chrenek P, Stockinger H, Fuertbauer E, Moser M, Haiko P, Fassler R, Alitalo K, Binder BR, Kerjaschki D, Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation. Blood. 2010 May 13;115(19):3997-4005 |
Lyar Ly1 antibody reactive clone | |
Results | Reference |
1 | J:160518 Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, Jenkins RB, Tihan T, Vandenberg SR, James CD, Tanaka K, Taylor MD, Weiss WA, Chesler L, Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010 May 15;24(10):1059-72 |
Lyn LYN proto-oncogene, Src family tyrosine kinase (Synonyms: Hck-2, Yamaguchi sarcoma viral (v-yes-1) oncogene homolog) | |
Results | Reference |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1* | J:55945 Wang JP, Chuang SM, Shen CL, Chen ST, Expression of Src family during development of the mouse nervous system. Biomed Res. 1998 OCT;19(5):315-325 |
Lypd1 Ly6/Plaur domain containing 1 (Synonyms: 2700050C12Rik, C530008O16Rik, Lynx2) | |
Results | Reference |
1 | J:326535 Petitpre C, Faure L, Uhl P, Fontanet P, Filova I, Pavlinkova G, Adameyko I, Hadjab S, Lallemend F, Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification. Nat Commun. 2022 Jul 5;13(1):3878 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
Lypd3 Ly6/Plaur domain containing 3 (Synonyms: 2310061G07Rik, C4.4A) | |
Results | Reference |
1* | J:169752 Kriegbaum MC, Jacobsen B, Hald A, Ploug M, Expression of C4.4A, a Structural uPAR Homolog, Reflects Squamous Epithelial Differentiation in the Adult Mouse and during Embryogenesis. J Histochem Cytochem. 2011 Feb;59(2):188-201 |
Lypd6 LY6/PLAUR domain containing 6 (Synonyms: E130115E03Rik) | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:281878 Yook C, Kim K, Kim D, Kang H, Kim SG, Kim E, Kim SY, A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice. Front Mol Neurosci. 2019;12:241 |
Lypd8l LY6/PLAUR domain containing 8 like (Synonyms: 2210407C18Rik) | |
Results | Reference |
1 | J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90 |
Lyst lysosomal trafficking regulator (Synonyms: D13Sfk13) | |
Results | Reference |
1 | J:33734 Perou CM, Moore KJ, Nagle DL, Misumi DJ, Woolf EA, McGrail SH, Holmgren L, Brody TH, Dussault BJ Jr, Monroe CA, Duyk GM, Pryor RJ, Li L, Justice MJ, Kaplan J, Identification of the murine beige gene by YAC complementation and positional cloning. Nat Genet. 1996 Jul;13(3):303-8 |
Lyve1 lymphatic vessel endothelial hyaluronan receptor 1 (Synonyms: 1200012G08Rik, lymphatic vessel endothelial HA receptor-1, Lyve-1, Xlkd1) | |
Results | Reference |
1 | J:284215 Auvinen K, Lokka E, Mokkala E, Jappinen N, Tyystjarvi S, Saine H, Peurla M, Shetty S, Elima K, Rantakari P, Salmi M, Fenestral diaphragms and PLVAP associations in liver sinusoidal endothelial cells are developmentally regulated. Sci Rep. 2019 Oct 30;9(1):15698 |
1 | J:152968 Bazigou E, Xie S, Chen C, Weston A, Miura N, Sorokin L, Adams R, Muro AF, Sheppard D, Makinen T, Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis. Dev Cell. 2009 Aug;17(2):175-86 |
1 | J:159868 Benezech C, White A, Mader E, Serre K, Parnell S, Pfeffer K, Ware CF, Anderson G, Caamano JH, Ontogeny of stromal organizer cells during lymph node development. J Immunol. 2010 Apr 15;184(8):4521-30 |
1 | J:240616 Benito-Jardon M, Klapproth S, Gimeno-LLuch I, Petzold T, Bharadwaj M, Muller DJ, Zuchtriegel G, Reichel CA, Costell M, The fibronectin synergy site re-enforces cell adhesion and mediates a crosstalk between integrin classes. Elife. 2017 Jan 16;6:e22264 |
1 | J:269938 Bovay E, Sabine A, Prat-Luri B, Kim S, Son K, Willrodt AH, Olsson C, Halin C, Kiefer F, Betsholtz C, Jeon NL, Luther SA, Petrova TV, Multiple roles of lymphatic vessels in peripheral lymph node development. J Exp Med. 2018 Nov 5;215(11):2760-2777 |
1 | J:302542 Cahill TJ, Sun X, Ravaud C, Villa Del Campo C, Klaourakis K, Lupu IE, Lord AM, Browne C, Jacobsen SEW, Greaves DR, Jackson DG, Cowley SA, James W, Choudhury RP, Vieira JM, Riley PR, Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart. Development. 2021 Feb 3;148(3):dev194563 |
1 | J:344154 Carlantoni C, Liekfeld LMH, Hemkemeyer SA, Schreier D, Saygi C, Kurelic R, Cardarelli S, Kalucka J, Schulte C, Beerens M, Mailer RK, Schaffer TE, Naro F, Pellegrini M, Nikolaev VO, Renne T, Frye M, The phosphodiesterase 2A controls lymphatic junctional maturation via cGMP-dependent notch signaling. Dev Cell. 2023 Dec 23; |
1 | J:217615 Chen HI, Poduri A, Numi H, Kivela R, Saharinen P, McKay AS, Raftrey B, Churko J, Tian X, Zhou B, Wu JC, Alitalo K, Red-Horse K, VEGF-C and aortic cardiomyocytes guide coronary artery stem development. J Clin Invest. 2014 Nov;124(11):4899-914 |
1 | J:254639 Chen L, Martino V, Dombkowski A, Williams T, West-Mays J, Gage PJ, AP-2beta Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development. Invest Ophthalmol Vis Sci. 2016 Mar;57(3):1072-81 |
1 | J:159824 Chen L, Mupo A, Huynh T, Cioffi S, Woods M, Jin C, McKeehan W, Thompson-Snipes L, Baldini A, Illingworth E, Tbx1 regulates Vegfr3 and is required for lymphatic vessel development. J Cell Biol. 2010 May 3;189(3):417-24 |
1 | J:207561 Dellinger MT, Meadows SM, Wynne K, Cleaver O, Brekken RA, Vascular endothelial growth factor receptor-2 promotes the development of the lymphatic vasculature. PLoS One. 2013;8(9):e74686 |
1 | J:215601 Gage PJ, Kuang C, Zacharias AL, The homeodomain transcription factor PITX2 is required for specifying correct cell fates and establishing angiogenic privilege in the developing cornea. Dev Dyn. 2014 Nov;243(11):1391-400 |
1 | J:228882 Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS, Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016 Jan 1;409(1):218-33 |
1* | J:137168 Gordon EJ, Gale NW, Harvey NL, Expression of the hyaluronan receptor LYVE-1 is not restricted to the lymphatic vasculature; LYVE-1 is also expressed on embryonic blood vessels. Dev Dyn. 2008 Jul;237(7):1901-9 |
2 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1 | J:287857 Gur-Cohen S, Yang H, Baksh SC, Miao Y, Levorse J, Kataru RP, Liu X, de la Cruz-Racelis J, Mehrara BJ, Fuchs E, Stem cell-driven lymphatic remodeling coordinates tissue regeneration. Science. 2019 Dec 6;366(6470):1218-1225 |
1 | J:217070 Hatch J, Mukouyama YS, Spatiotemporal mapping of vascularization and innervation in the fetal murine intestine. Dev Dyn. 2015 Jan;244(1):56-68 |
1* | J:333946 Hattori Y, Kato D, Murayama F, Koike S, Asai H, Yamasaki A, Naito Y, Kawaguchi A, Konishi H, Prinz M, Masuda T, Wake H, Miyata T, CD206(+) macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia. Cell Rep. 2023 Feb 7;42(2):112092 |
1* | J:135686 Hirashima M, Sano K, Morisada T, Murakami K, Rossant J, Suda T, Lymphatic vessel assembly is impaired in Aspp1-deficient mouse embryos. Dev Biol. 2008 Apr 1;316(1):149-59 |
1 | J:321245 Hu S, Mahadevan A, Elysee IF, Choi J, Souchet NR, Bae GH, Taboada AK, Sanketi B, Duhamel GE, Sevier CS, Tao G, Kurpios NA, The asymmetric Pitx2 gene regulates gut muscular-lacteal development and protects against fatty liver disease. Cell Rep. 2021 Nov 23;37(8):110030 |
1 | J:216228 Inoue S, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y, New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet. 2014 Dec 15;23(24):6553-66 |
1* | J:293098 Jafree DJ, Moulding D, Kolatsi-Joannou M, Perretta Tejedor N, Price KL, Milmoe NJ, Walsh CL, Correra RM, Winyard PJ, Harris PC, Ruhrberg C, Walker-Samuel S, Riley PR, Woolf AS, Scambler PJ, Long DA, Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease. Elife. 2019 Dec 6;8:e48183 |
1 | J:329963 Janardhan HP, Dresser K, Hutchinson L, Trivedi CM, Pathological MAPK activation-mediated lymphatic basement membrane disruption causes lymphangiectasia that is treatable with ravoxertinib. JCI Insight. 2022 Sep 8;7(17):e153033 |
2 | J:302486 Jiang X, Tian W, Granucci EJ, Tu AB, Kim D, Dahms P, Pasupneti S, Peng G, Kim Y, Lim AH, Espinoza FH, Cribb M, Dixon JB, Rockson SG, Semenza GL, Nicolls MR, Decreased lymphatic HIF-2alpha accentuates lymphatic remodeling in lymphedema. J Clin Invest. 2020 Oct 1;130(10):5562-5575 |
2* | J:139639 Juszynski M, Ciszek B, Stachurska E, Jablonska A, Ratajska A, Development of lymphatic vessels in mouse embryonic and early postnatal hearts. Dev Dyn. 2008 Sep 24;237(10):2973-2986 |
1 | J:173649 Kanady JD, Dellinger MT, Munger SJ, Witte MH, Simon AM, Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax. Dev Biol. 2011 Jun 15;354(2):253-66 |
1* | J:122404 Kim KE, Sung HK, Koh GY, Lymphatic development in mouse small intestine. Dev Dyn. 2007 Jul;236(7):2020-5 |
2 | J:342552 Kulikauskas MR, Oatley M, Yu T, Liu Z, Matsumura L, Kidder E, Ruter D, Bautch VL, Endothelial cell SMAD6 balances Alk1 function to regulate adherens junctions and hepatic vascular development. Development. 2023 Nov 1;150(21) |
2 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
1 | J:332090 Lioux G, Liu X, Temino S, Oxendine M, Ayala E, Ortega S, Kelly RG, Oliver G, Torres M, A Second Heart Field-Derived Vasculogenic Niche Contributes to Cardiac Lymphatics. Dev Cell. 2020 Feb 10;52(3):350-363.e6 |
1 | J:299970 Liu X, De la Cruz E, Gu X, Balint L, Oxendine-Burns M, Terrones T, Ma W, Kuo HH, Lantz C, Bansal T, Thorp E, Burridge P, Jakus Z, Herz J, Cleaver O, Torres M, Oliver G, Lymphoangiocrine signals promote cardiac growth and repair. Nature. 2020 Dec;588(7839):705-711 |
1 | J:316476 Ma W, Gil HJ, Liu X, Diebold LP, Morgan MA, Oxendine-Burns MJ, Gao P, Chandel NS, Oliver G, Mitochondrial respiration controls the Prox1-Vegfr3 feedback loop during lymphatic endothelial cell fate specification and maintenance. Sci Adv. 2021 Apr;7(18) |
1 | J:329978 Maruyama K, Miyagawa-Tomita S, Haneda Y, Kida M, Matsuzaki F, Imanaka-Yoshida K, Kurihara H, The cardiopharyngeal mesoderm contributes to lymphatic vessel development in mouse. Elife. 2022 Oct 5;11:e81515 |
2* | J:278916 Maruyama K, Miyagawa-Tomita S, Mizukami K, Matsuzaki F, Kurihara H, Isl1-expressing non-venous cell lineage contributes to cardiac lymphatic vessel development. Dev Biol. 2019 Aug 15;452(2):134-143 |
1 | J:306872 Maruyama K, Naemura K, Arima Y, Uchijima Y, Nagao H, Yoshihara K, Singh MK, Uemura A, Matsuzaki F, Yoshida Y, Kurihara Y, Miyagawa-Tomita S, Kurihara H, Semaphorin3E-PlexinD1 signaling in coronary artery and lymphatic vessel development with clinical implications in myocardial recovery. iScience. 2021 Apr 23;24(4):102305 |
1 | J:358584 McCarter AL, Khalid A, Yi Y, Monroy M, Zhao H, Rios JJ, Dellinger MT, Bone development and fracture healing is normal in mice that have a defect in the development of the lymphatic system. Lymphology. 2020;53(4):162-171 |
1 | J:225118 Mirza M, Pang MF, Zaini MA, Haiko P, Tammela T, Alitalo K, Philipson L, Fuxe J, Sollerbrant K, Essential role of the coxsackie- and adenovirus receptor (CAR) in development of the lymphatic system in mice. PLoS One. 2012;7(5):e37523 |
1 | J:262023 Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K, Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling. Circ Res. 2017 Apr 14;120(8):1276-1288 |
1 | J:275825 Norman TA Jr, Gower AC, Chen F, Fine A, Transcriptional landscape of pulmonary lymphatic endothelial cells during fetal gestation. PLoS One. 2019;14(5):e0216795 |
1 | J:149138 Norrmen C, Ivanov KI, Cheng J, Zangger N, Delorenzi M, Jaquet M, Miura N, Puolakkainen P, Horsley V, Hu J, Augustin HG, Yla-Herttuala S, Alitalo K, Petrova TV, FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1. J Cell Biol. 2009 May 4;185(3):439-57 |
1 | J:317760 Ochsenbein AM, Karaman S, Proulx ST, Goldmann R, Chittazhathu J, Dasargyri A, Chong C, Leroux JC, Stanley ER, Detmar M, Regulation of lymphangiogenesis in the diaphragm by macrophages and VEGFR-3 signaling. Angiogenesis. 2016 Oct;19(4):513-24 |
1 | J:211806 Outeda P, Huso DL, Fisher SA, Halushka MK, Kim H, Qian F, Germino GG, Watnick T, Polycystin signaling is required for directed endothelial cell migration and lymphatic development. Cell Rep. 2014 May 8;7(3):634-44 |
1 | J:308707 Paulson D, Harms R, Ward C, Latterell M, Pazour GJ, Fink DM, Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation. Front Cell Dev Biol. 2021;9:672625 |
1 | J:313370 Pena-Jimenez D, Fontenete S, Megias D, Fustero-Torre C, Grana-Castro O, Castellana D, Loewe R, Perez-Moreno M, Lymphatic vessels interact dynamically with the hair follicle stem cell niche during skin regeneration in vivo. EMBO J. 2019 Oct 1;38(19):e101688 |
2 | J:239420 Rantakari P, Jappinen N, Lokka E, Mokkala E, Gerke H, Peuhu E, Ivaska J, Elima K, Auvinen K, Salmi M, Fetal liver endothelium regulates the seeding of tissue-resident macrophages. Nature. 2016 Oct 20;538(7625):392-396 |
1 | J:249238 Roukens MG, Peterson-Maduro J, Padberg Y, Jeltsch M, Leppanen VM, Bos FL, Alitalo K, Schulte-Merker S, Schulte D, Functional Dissection of the CCBE1 Protein: A Crucial Requirement for the Collagen Repeat Domain. Circ Res. 2015 May 8;116(10):1660-9 |
1 | J:181330 Sabine A, Agalarov Y, Maby-El Hajjami H, Jaquet M, Hagerling R, Pollmann C, Bebber D, Pfenniger A, Miura N, Dormond O, Calmes JM, Adams RH, Makinen T, Kiefer F, Kwak BR, Petrova TV, Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation. Dev Cell. 2012 Feb 14;22(2):430-45 |
1* | J:145448 Shimoda H, Immunohistochemical demonstration of Angiopoietin-2 in lymphatic vascular development. Histochem Cell Biol. 2009 Feb;131(2):231-8 |
1 | J:222173 Solano ME, Kowal MK, O'Rourke GE, Horst AK, Modest K, Plosch T, Barikbin R, Remus CC, Berger RG, Jago C, Ho H, Sass G, Parker VJ, Lydon JP, DeMayo FJ, Hecher K, Karimi K, Arck PC, Progesterone and HMOX-1 promote fetal growth by CD8+ T cell modulation. J Clin Invest. 2015 Apr;125(4):1726-38 |
1 | J:158959 Srinivasan RS, Geng X, Yang Y, Wang Y, Mukatira S, Studer M, Porto MP, Lagutin O, Oliver G, The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells. Genes Dev. 2010 Apr 1;24(7):696-707 |
1 | J:269939 Stefanini L, Lee RH, Paul DS, O'Shaughnessy EC, Ghalloussi D, Jones CI, Boulaftali Y, Poe KO, Piatt R, Kechele DO, Caron KM, Hahn KM, Gibbins JM, Bergmeier W, Functional redundancy between RAP1 isoforms in murine platelet production and function. Blood. 2018 Nov 1;132(18):1951-1962 |
1 | J:231970 Stevens SM, Gise Av, VanDusen N, Zhou B, Pu WT, Epicardium is required for cardiac seeding by yolk sac macrophages, precursors of resident macrophages of the adult heart. Dev Biol. 2016 May 15;413(2):153-9 |
1* | J:226501 Uchida Y, James JM, Suto F, Mukouyama YS, Class 3 semaphorins negatively regulate dermal lymphatic network formation. Biol Open. 2015;4(9):1194-205 |
1 | J:160267 Uhrin P, Zaujec J, Breuss JM, Olcaydu D, Chrenek P, Stockinger H, Fuertbauer E, Moser M, Haiko P, Fassler R, Alitalo K, Binder BR, Kerjaschki D, Novel function for blood platelets and podoplanin in developmental separation of blood and lymphatic circulation. Blood. 2010 May 13;115(19):3997-4005 |
1 | J:150308 Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009 May 1;182(9):5439-45 |
1 | J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34 |
2 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:244845 Wong BW, Wang X, Zecchin A, Thienpont B, Cornelissen I, Kalucka J, Garcia-Caballero M, Missiaen R, Huang H, Bruning U, Blacher S, Vinckier S, Goveia J, Knobloch M, Zhao H, Dierkes C, Shi C, Hagerling R, Moral-Darde V, Wyns S, Lippens M, Jessberger S, Fendt SM, Luttun A, Noel A, Kiefer F, Ghesquiere B, Moons L, Schoonjans L, Dewerchin M, Eelen G, Lambrechts D, Carmeliet P, The role of fatty acid beta-oxidation in lymphangiogenesis. Nature. 2017 Feb 02;542(7639):49-54 |
1 | J:193198 Wu B, Zhang Z, Lui W, Chen X, Wang Y, Chamberlain AA, Moreno-Rodriguez RA, Markwald RR, O'Rourke BP, Sharp DJ, Zheng D, Lenz J, Baldwin HS, Chang CP, Zhou B, Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling. Cell. 2012 Nov 21;151(5):1083-96 |
1 | J:241335 Yang Y, Enis D, Zheng H, Chia S, Yang J, Chen M, Dhillon V, Papayannapoulou T, Kahn ML, Cell Adhesion Mediated by VCAM-ITGalpha9 Interactions Enables Lymphatic Development. Arterioscler Thromb Vasc Biol. 2015 May;35(5):1179-89 |
1 | J:184806 Yao LC, Baluk P, Srinivasan RS, Oliver G, McDonald DM, Plasticity of button-like junctions in the endothelium of airway lymphatics in development and inflammation. Am J Pathol. 2012 Jun;180(6):2561-75 |
1* | J:171387 Zhang H, Tse J, Hu X, Witte M, Bernas M, Kang J, Tilahun F, Hong YK, Qiu M, Chen L, Novel discovery of LYVE-1 expression in the hyaloid vascular system. Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6157-61 |
1 | J:196696 Zou Z, Enis DR, Bui H, Khandros E, Kumar V, Jakus Z, Thom C, Yang Y, Dhillon V, Chen M, Lu M, Weiss MJ, Kahn ML, The secreted lymphangiogenic factor CCBE1 is essential for fetal liver erythropoiesis. Blood. 2013 Apr 18;121(16):3228-36 |
Lyz1 lysozyme 1 (Synonyms: Lyz, Lzp-s, renal amyloidosis) | |
Results | Reference |
1 | J:283354 Guiu J, Hannezo E, Yui S, Demharter S, Ulyanchenko S, Maimets M, Jorgensen A, Perlman S, Lundvall L, Mamsen LS, Larsen A, Olesen RH, Andersen CY, Thuesen LL, Hare KJ, Pers TH, Khodosevich K, Simons BD, Jensen KB, Tracing the origin of adult intestinal stem cells. Nature. 2019 Jun;570(7759):107-111 |
1* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
Lyz2 lysozyme 2 (Synonyms: Lys, Lysm, Lyzs, Lzm, Lzm-s1, Lzp) | |
Results | Reference |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
M1ap meiosis 1 associated protein (Synonyms: D6Mm5e) | |
Results | Reference |
2 | J:347973 Li Y, Wu Y, Khan I, Zhou J, Lu Y, Ye J, Liu J, Xie X, Hu C, Jiang H, Fan S, Zhang H, Zhang Y, Jiang X, Xu B, Ma H, Shi Q, M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination. EMBO Rep. 2023 Feb 6;24(2):e55778 |
Macf1 microtubule-actin crosslinking factor 1 (Synonyms: Acf7, Aclp7, mKIAA0465, trabeculin alpha) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:61545 Karakesisoglou I, Yang Y, Fuchs E, An epidermal plakin that integrates actin and microtubule networks at cellular junctions. J Cell Biol. 2000 Apr 3;149(1):195-208 |
Macrod1 mono-ADP ribosylhydrolase 1 (Synonyms: D930010J01Rik) | |
Results | Reference |
1 | J:266603 Ito H, Morishita R, Mizuno M, Kawamura N, Tabata H, Nagata KI, Biochemical and Morphological Characterization of a Neurodevelopmental Disorder-Related Mono-ADP-Ribosylhydrolase, MACRO Domain Containing 2. Dev Neurosci. 2018;40(3):278-287 |
Macrod2 mono-ADP ribosylhydrolase 2 (Synonyms: 1110033L15Rik, 2610107G07Rik, 2900006F19Rik) | |
Results | Reference |
2* | J:266603 Ito H, Morishita R, Mizuno M, Kawamura N, Tabata H, Nagata KI, Biochemical and Morphological Characterization of a Neurodevelopmental Disorder-Related Mono-ADP-Ribosylhydrolase, MACRO Domain Containing 2. Dev Neurosci. 2018;40(3):278-287 |
1* | J:168195 Maas NM, Van de Putte T, Melotte C, Francis A, Schrander-Stumpel CT, Sanlaville D, Genevieve D, Lyonnet S, Dimitrov B, Devriendt K, Fryns JP, Vermeesch JR, The C20orf133 gene is disrupted in a patient with Kabuki syndrome. J Med Genet. 2007 Sep;44(9):562-9 |
Macroh2a1 macroH2A.1 histone (Synonyms: H2AF12M, H2afy, MACROH2A1.2, mH2a1) | |
Results | Reference |
1 | J:330439 Liu H, He L, Cheng Q, Luo W, Zhao T, Yang D, Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states. Int J Mol Med. 2022 Nov;50(5) |
1* | J:333071 Ma H, Su L, Xia W, Wang W, Tan G, Jiao J, MacroH2A1.2 deficiency leads to neural stem cell differentiation defects and autism-like behaviors. EMBO Rep. 2021 Jul 5;22(7):e52150 |
Madcam1 mucosal vascular addressin cell adhesion molecule 1 (Synonyms: MGC:35998) | |
Results | Reference |
1 | J:159868 Benezech C, White A, Mader E, Serre K, Parnell S, Pfeffer K, Ware CF, Anderson G, Caamano JH, Ontogeny of stromal organizer cells during lymph node development. J Immunol. 2010 Apr 15;184(8):4521-30 |
2* | J:78842 Nishioka E, Tanaka T, Yoshida H, Matsumura K, Nishikawa S, Naito A, Inoue J, Funasaka Y, Ichihashi M, Miyasaka M, Nishikawa S, Mucosal addressin cell adhesion molecule 1 plays an unexpected role in the development of mouse guard hair. J Invest Dermatol. 2002 Sep;119(3):632-8 |
1 | J:338451 Shintani A, Fukai S, Nobusawa R, Taniguchi K, Hatatani T, Nagai H, Sakai T, Yoshimura T, Miyasaka M, Hayasaka H, Dach1 transcription factor regulates the expression of peripheral node addressin and lymphocyte trafficking in lymph nodes. Curr Res Immunol. 2022;3:175-185 |
1 | J:157747 van de Pavert SA, Olivier BJ, Goverse G, Vondenhoff MF, Greuter M, Beke P, Kusser K, Hopken UE, Lipp M, Niederreither K, Blomhoff R, Sitnik K, Agace WW, Randall TD, de Jonge WJ, Mebius RE, Chemokine CXCL13 is essential for lymph node initiation and is induced by retinoic acid and neuronal stimulation. Nat Immunol. 2009 Nov;10(11):1193-9 |
1 | J:137812 Vondenhoff MF, Desanti GE, Cupedo T, Bertrand JY, Cumano A, Kraal G, Mebius RE, Golub R, Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner. J Leukoc Biol. 2008 Jul;84(1):152-61 |
1 | J:150308 Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009 May 1;182(9):5439-45 |
1 | J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34 |
1 | J:64018 Wang CC, Biben C, Robb L, Nassir F, Barnett L, Davidson NO, Koentgen F, Tarlinton D, Harvey RP, Homeodomain factor Nkx2-3 controls regional expression of leukocyte homing coreceptor MAdCAM-1 in specialized endothelial cells of the viscera. Dev Biol. 2000 Aug 15;224(2):152-67 |
Madd MAP-kinase activating death domain (Synonyms: 9630059K23Rik, mKIAA0358, Rab3 GEP) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:343445 Lewis MA, Schulte J, Matthews L, Vaden KI Jr, Steves CJ, Williams FMK, Schulte BA, Dubno JR, Steel KP, Accurate phenotypic classification and exome sequencing allow identification of novel genes and variants associated with adult-onset hearing loss. PLoS Genet. 2023 Nov;19(11):e1011058 |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Mael maelstrom spermatogenic transposon silencer (Synonyms: 4933405K18Rik) | |
Results | Reference |
1 | J:155865 Aravin AA, van der Heijden GW, Castaneda J, Vagin VV, Hannon GJ, Bortvin A, Cytoplasmic compartmentalization of the fetal piRNA pathway in mice. PLoS Genet. 2009 Dec;5(12):e1000764 |
1 | J:112036 Costa Y, Speed RM, Gautier P, Semple CA, Maratou K, Turner JM, Cooke HJ, Mouse MAELSTROM: the link between meiotic silencing of unsynapsed chromatin and microRNA pathway?. Hum Mol Genet. 2006 Aug 1;15(15):2324-34 |
1 | J:213575 Malki S, van der Heijden GW, O'Donnell KA, Martin SL, Bortvin A, A role for retrotransposon LINE-1 in fetal oocyte attrition in mice. Dev Cell. 2014 Jun 9;29(5):521-33 |
Maf MAF bZIP transcription factor (Synonyms: 2810401A20Rik, A230108G15Rik, c-maf) | |
Results | Reference |
1 | J:223109 Choi JJ, Ting CT, Trogrlic L, Milevski SV, Familari M, Martinez G, de Iongh RU, A role for smoothened during murine lens and cornea development. PLoS One. 2014;9(9):e108037 |
1 | J:184447 Hu J, Huang T, Li T, Guo Z, Cheng L, c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections. J Neurosci. 2012 Apr 18;32(16):5362-73 |
1 | J:92087 Imaki J, Tsuchiya K, Mishima T, Onodera H, Kim JI, Yoshida K, Ikeda H, Sakai M, Developmental contribution of c-maf in the kidney: distribution and developmental study of c-maf mRNA in normal mice kidney and histological study of c-maf knockout mice kidney and liver. Biochem Biophys Res Commun. 2004 Aug 6;320(4):1323-7 |
1* | J:85738 MacLean HE, Kim JI, Glimcher MJ, Wang J, Kronenberg HM, Glimcher LH, Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development. Dev Biol. 2003 Oct 1;262(1):51-63 |
1 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
1 | J:207861 Manthey AL, Lachke SA, FitzGerald PG, Mason RW, Scheiblin DA, McDonald JH, Duncan MK, Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development. Mech Dev. 2014 Feb;131:86-110 |
1 | J:122566 Simirskii VN, Wang Y, Duncan MK, Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype. Dev Biol. 2007 Jun 15;306(2):658-68 |
1 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
1* | J:136711 Zhao H, Yang T, Madakashira BP, Thiels CA, Bechtle CA, Garcia CM, Zhang H, Yu K, Ornitz DM, Beebe DC, Robinson ML, Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. Dev Biol. 2008 Jun 15;318(2):276-88 |
Maf1 MAF1 homolog, negative regulator of RNA polymerase III (Synonyms: 1110068E11Rik, Maf1) | |
Results | Reference |
3 | J:343468 Li Y, Xiao D, Chen H, Zheng XFS, Xiang M, Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms. iScience. 2023 Dec 15;26(12):108544 |
Mafa MAF bZIP transcription factor A (Synonyms: RIPE3b1) | |
Results | Reference |
1 | J:200985 Cai EP, Wu X, Schroer SA, Elia AJ, Nostro MC, Zacksenhaus E, Woo M, Retinoblastoma tumor suppressor protein in pancreatic progenitors controls alpha- and beta-cell fate. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14723-8 |
1 | J:184447 Hu J, Huang T, Li T, Guo Z, Cheng L, c-Maf is required for the development of dorsal horn laminae III/IV neurons and mechanoreceptive DRG axon projections. J Neurosci. 2012 Apr 18;32(16):5362-73 |
1 | J:257425 Kim DS, Song L, Wang J, Wu H, Gu G, Sugi Y, Li Z, Wang H, GRP94 Is an Essential Regulator of Pancreatic beta-Cell Development, Mass, and Function in Male Mice. Endocrinology. 2018 Feb 1;159(2):1062-1073 |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
1* | J:201764 Yamamoto K, Matsuoka TA, Kawashima S, Takebe S, Kubo N, Miyatsuka T, Kaneto H, Shimomura I, A novel function of Onecut1 protein as a negative regulator of MafA gene expression. J Biol Chem. 2013 Jul 26;288(30):21648-58 |
1 | J:144661 Zhang W, Feng D, Li Y, Iida K, McGrath B, Cavener DR, PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis. Cell Metab. 2006 Dec;4(6):491-7 |
Mafb MAF bZIP transcription factor B (Synonyms: Kreisler, Krml, Krml1) | |
Results | Reference |
1 | J:278104 Acebedo AR, Suzuki K, Hino S, Alcantara MC, Sato Y, Haga H, Matsumoto KI, Nakao M, Shimamura K, Takeo T, Nakagata N, Miyagawa S, Nishinakamura R, Adelstein RS, Yamada G, Mesenchymal actomyosin contractility is required for androgen-driven urethral masculinization in mice. Commun Biol. 2019;2:95 |
2 | J:331894 Alcantara MC, Suzuki K, Acebedo AR, Kajioka D, Hirohata S, Kaisho T, Hatano Y, Yamagata K, Takahashi S, Yamada G, Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice. iScience. 2022 Dec 22;25(12):105609 |
1 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
3* | J:306453 Kajioka D, Suzuki K, Matsushita S, Hino S, Sato T, Takada S, Isono K, Takeo T, Kajimoto M, Nakagata N, Nakao M, Suyama M, DeFalco T, Miyagawa S, Yamada G, Sexual fate of murine external genitalia development: Conserved transcriptional competency for male-biased genes in both sexes. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2024067118 |
1 | J:336092 Knowles SJ, Stafford AM, Zaman T, Angara K, Williams MR, Newbern JM, Vogt D, Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs. Development. 2023 May 15;150(10):dev201371 |
1* | J:263032 Magella B, Mahoney R, Adam M, Potter SS, Reduced Abd-B Hox function during kidney development results in lineage infidelity. Dev Biol. 2018 Jun 15;438(2):84-93 |
1 | J:178995 Stam FJ, Hendricks TJ, Zhang J, Geiman EJ, Francius C, Labosky PA, Clotman F, Goulding M, Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program. Development. 2012 Jan;139(1):179-90 |
2* | J:216758 Suzuki K, Numata T, Suzuki H, Raga DD, Ipulan LA, Yokoyama C, Matsushita S, Hamada M, Nakagata N, Nishinakamura R, Kume S, Takahashi S, Yamada G, Sexually dimorphic expression of Mafb regulates masculinization of the embryonic urethral formation. Proc Natl Acad Sci U S A. 2014 Nov 18;111(46):16407-12 |
1 | J:159849 Wang Y, Dye CA, Sohal V, Long JE, Estrada RC, Roztocil T, Lufkin T, Deisseroth K, Baraban SC, Rubenstein JL, Dlx5 and Dlx6 regulate the development of parvalbumin-expressing cortical interneurons. J Neurosci. 2010 Apr 14;30(15):5334-45 |
2 | J:207904 Yu WM, Appler JM, Kim YH, Nishitani AM, Holt JR, Goodrich LV, A Gata3-Mafb transcriptional network directs post-synaptic differentiation in synapses specialized for hearing. Elife. 2013;2:e01341 |
Maff v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian) | |
Results | Reference |
1 | J:274581 Agrawal SA, Anand D, Siddam AD, Kakrana A, Dash S, Scheiblin DA, Dang CA, Terrell AM, Waters SM, Singh A, Motohashi H, Yamamoto M, Lachke SA, Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract. Hum Genet. 2015 Jul;134(7):717-35 |
1* | J:56405 Onodera K, Shavit JA, Motohashi H, Katsuoka F, Akasaka JE, Engel JD, Yamamoto M, Characterization of the murine mafF gene. J Biol Chem. 1999 Jul 23;274(30):21162-9 |
Mafg v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian) (Synonyms: C630022N07Rik) | |
Results | Reference |
2 | J:274581 Agrawal SA, Anand D, Siddam AD, Kakrana A, Dash S, Scheiblin DA, Dang CA, Terrell AM, Waters SM, Singh A, Motohashi H, Yamamoto M, Lachke SA, Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract. Hum Genet. 2015 Jul;134(7):717-35 |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
Mafk v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) (Synonyms: NF-E2, Nfe2u, p18 NF-E2) | |
Results | Reference |
1 | J:274581 Agrawal SA, Anand D, Siddam AD, Kakrana A, Dash S, Scheiblin DA, Dang CA, Terrell AM, Waters SM, Singh A, Motohashi H, Yamamoto M, Lachke SA, Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract. Hum Genet. 2015 Jul;134(7):717-35 |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
Mag myelin-associated glycoprotein (Synonyms: Gma, siglec-4a) | |
Results | Reference |
1* | J:337458 Waldhauser V, Baroti T, Frob F, Wegner M, PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12) |
1 | J:154660 Zhang Y, Argaw AT, Gurfein BT, Zameer A, Snyder BJ, Ge C, Lu QR, Rowitch DH, Raine CS, Brosnan CF, John GR, Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination. Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19162-7 |
Mageb4 MAGE family member B4 (Synonyms: CN716893, Mage-b4, mMage-b4) | |
Results | Reference |
1 | J:70948 Osterlund C, Tohonen V, Forslund KO, Nordqvist K, Mage-b4, a novel melanoma antigen (MAGE) gene specifically expressed during germ cell differentiation. Cancer Res. 2000 Feb 15;60(4):1054-61 |
Maged1 MAGE family member D1 (Synonyms: 2810433C11Rik, 5430405L04Rik, Dlxin-1, DXBwg1492e, MAGE-D1, Nrage) | |
Results | Reference |
1 | J:329949 Yuan H, Xie B, Yu X, Lin C, Li M, Zhang Y, Zou X, Lu M, Zhao M, Wen X, A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development. Front Physiol. 2022;13:981311 |
Mageh1 MAGE family member H1 (Synonyms: 2010107K23Rik, APR-1, APR1) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Magel2 MAGE family member L2 (Synonyms: Mage-l2, NDNL1, nM15, ns7) | |
Results | Reference |
1 | J:233299 Kamaludin AA, Smolarchuk C, Bischof JM, Eggert R, Greer JJ, Ren J, Lee JJ, Yokota T, Berry FB, Wevrick R, Muscle dysfunction caused by loss of Magel2 in a mouse model of Prader-Willi and Schaaf-Yang syndromes. Hum Mol Genet. 2016 Sep 1;25(17):3798-3809 |
2 | J:315293 Kumamoto T, Toma K, Gunadi, McKenna WL, Kasukawa T, Katzman S, Chen B, Hanashima C, Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013 Mar 28;3(3):931-45 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Magoh mago homolog, exon junction complex core component (Synonyms: Mago-m, Mos2) | |
Results | Reference |
1* | J:104317 Islam S, Montgomery RK, Fialkovich JJ, Grand RJ, Developmental and regional expression and localization of mRNAs encoding proteins involved in RNA translocation. J Histochem Cytochem. 2005 Dec;53(12):1501-9 |
Malat1 metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA) (Synonyms: 2210401K01Rik, 9430072K23Rik, NEAT2) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:258363 Ushakov K, Koffler-Brill T, Rom A, Perl K, Ulitsky I, Avraham KB, Genome-wide identification and expression profiling of long non-coding RNAs in auditory and vestibular systems. Sci Rep. 2017 Aug 17;7(1):8637 |
1 | J:331893 Yang J, Zhang L, Li Y, Chen M, Identifying key m(6)A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses. Front Genet. 2022;13:974357 |
Mamdc2 MAM domain containing 2 (Synonyms: 1200015L10Rik, mamcan) | |
Results | Reference |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Maml1 mastermind like transcriptional coactivator 1 (Synonyms: D930008C07Rik, Mam-1, mKIAA0200) | |
Results | Reference |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Mamld1 mastermind-like domain containing 1 (Synonyms: G630014P10Rik) | |
Results | Reference |
1 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
Man1a mannosidase 1, alpha (Synonyms: mannosyl-oligosaccharide alpha-1,2-mannosidase, PCR1) | |
Results | Reference |
1* | J:119977 Tremblay LO, Nagy Kovacs E, Daniels E, Wong NK, Sutton-Smith M, Morris HR, Dell A, Marcinkiewicz E, Seidah NG, McKerlie C, Herscovics A, Respiratory distress and neonatal lethality in mice lacking Golgi alpha1,2-mannosidase IB involved in N-glycan maturation. J Biol Chem. 2007 Jan 26;282(4):2558-66 |
Man1a2 mannosidase, alpha, class 1A, member 2 (Synonyms: Man1b) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:119977 Tremblay LO, Nagy Kovacs E, Daniels E, Wong NK, Sutton-Smith M, Morris HR, Dell A, Marcinkiewicz E, Seidah NG, McKerlie C, Herscovics A, Respiratory distress and neonatal lethality in mice lacking Golgi alpha1,2-mannosidase IB involved in N-glycan maturation. J Biol Chem. 2007 Jan 26;282(4):2558-66 |
Man1c1 mannosidase, alpha, class 1C, member 1 | |
Results | Reference |
1* | J:119977 Tremblay LO, Nagy Kovacs E, Daniels E, Wong NK, Sutton-Smith M, Morris HR, Dell A, Marcinkiewicz E, Seidah NG, McKerlie C, Herscovics A, Respiratory distress and neonatal lethality in mice lacking Golgi alpha1,2-mannosidase IB involved in N-glycan maturation. J Biol Chem. 2007 Jan 26;282(4):2558-66 |
Maoa monoamine oxidase A (Synonyms: 1110061B18Rik, MAO-A, MGC:27811) | |
Results | Reference |
1* | J:286599 Song NN, Ma P, Zhang Q, Zhang L, Wang H, Zhang L, Zhu L, He CH, Mao B, Ding YQ, Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199 |
1* | J:175921 Wang CC, Borchert A, Ugun-Klusek A, Tang LY, Lui WT, Chu CY, Billett E, Kuhn H, Ufer C, Monoamine oxidase a expression is vital for embryonic brain development by modulating developmental apoptosis. J Biol Chem. 2011 Aug 12;286(32):28322-30 |
Maob monoamine oxidase B (Synonyms: 6330414K01Rik, MAO-B) | |
Results | Reference |
1* | J:85074 Vitalis T, Alvarez C, Chen K, Shih JC, Gaspar P, Cases O, Developmental expression pattern of monoamine oxidases in sensory organs and neural crest derivatives. J Comp Neurol. 2003 Sep 22;464(3):392-403 |
1* | J:175921 Wang CC, Borchert A, Ugun-Klusek A, Tang LY, Lui WT, Chu CY, Billett E, Kuhn H, Ufer C, Monoamine oxidase a expression is vital for embryonic brain development by modulating developmental apoptosis. J Biol Chem. 2011 Aug 12;286(32):28322-30 |
Map1a microtubule-associated protein 1 A (Synonyms: 6330416M19Rik, Mtap-1, Mtap1, Mtap1a) | |
Results | Reference |
1 | J:54791 Faussone-Pellegrini MS, Matini P, DeFelici M, The cytoskeleton of the myenteric neurons during murine embryonic life. Anat Embryol (Berl). 1999 May;199(5):459-69 |
Map1b microtubule-associated protein 1B (Synonyms: LC1, MAP5, Mtap1b, Mtap-5, Mtap5) | |
Results | Reference |
1 | J:187391 Pacal M, Bremner R, Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Dev Dyn. 2012 Oct;241(10):1525-44 |
Map1lc3a microtubule-associated protein 1 light chain 3 alpha (Synonyms: 1010001H21Rik, 4922501H04Rik, LC3, LC3a) | |
Results | Reference |
1 | J:233601 Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP, Harwood CA, Byrne C, O'Shaughnessy RF, Bergamaschi D, Constitutive Autophagy and Nucleophagy during Epidermal Differentiation. J Invest Dermatol. 2016 Jul;136(7):1460-70 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
2* | J:190998 Yang JW, Zhu LX, Yuan GH, Chen YX, Zhang L, Zhang L, Chen Z, Autophagy appears during the development of the mouse lower first molar. Histochem Cell Biol. 2013 Jan;139(1):109-18 |
Map1lc3b microtubule-associated protein 1 light chain 3 beta (Synonyms: 1010001C15Rik, Atg8, LC3b, Map1lc3) | |
Results | Reference |
1 | J:235665 He S, Limi S, McGreal RS, Xie Q, Brennan LA, Kantorow WL, Kokavec J, Majumdar R, Hou H Jr, Edelmann W, Liu W, Ashery-Padan R, Zavadil J, Kantorow M, Skoultchi AI, Stopka T, Cvekl A, Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation. Development. 2016 Jun 1;143(11):1937-47 |
3 | J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
2 | J:280538 Yeganeh B, Lee J, Ermini L, Lok I, Ackerley C, Post M, Autophagy is required for lung development and morphogenesis. J Clin Invest. 2019 Jun 4;129(7):2904-2919 |
Map2 microtubule-associated protein 2 (Synonyms: G1-397-34, MAP-2, Mtap2, repro4) | |
Results | Reference |
1 | J:225119 Aida T, Ito Y, Takahashi YK, Tanaka K, Overstimulation of NMDA receptors impairs early brain development in vivo. PLoS One. 2012;7(5):e36853 |
1 | J:68904 Brouns MR, Matheson SF, Settleman J, p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation. Nat Cell Biol. 2001 Apr;3(4):361-7 |
2 | J:102162 Cicero S, Herrup K, Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci. 2005 Oct 19;25(42):9658-68 |
1* | J:74080 Del Rio JA, Martinez A, Auladell C, Soriano E, Developmental history of the subplate and developing white matter in the murine neocortex. Neuronal organization and relationship with the main afferent systems at embryonic and perinatal stages. Cereb Cortex. 2000 Aug;10(8):784-801 |
1* | J:359964 DeSpenza T Jr, Singh A, Allington G, Zhao S, Lee J, Kiziltug E, Prina ML, Desmet N, Dang HQ, Fields J, Nelson-Williams C, Zhang J, Mekbib KY, Dennis E, Mehta NH, Duy PQ, Shimelis H, Walsh LK, Marlier A, Deniz E, Lake EMR, Constable RT, Hoffman EJ, Lifton RP, Gulledge A, Fiering S, Moreno-De-Luca A, Haider S, Alper SL, Jin SC, Kahle KT, Luikart BW, Pathogenic variants in autism gene KATNAL2 cause hydrocephalus and disrupt neuronal connectivity by impairing ciliary microtubule dynamics. Proc Natl Acad Sci U S A. 2024 Jul 2;121(27):e2314702121 |
1 | J:139119 Fan X, Kim HJ, Bouton D, Warner M, Gustafsson JA, Expression of liver X receptor beta is essential for formation of superficial cortical layers and migration of later-born neurons. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13445-50 |
1 | J:54791 Faussone-Pellegrini MS, Matini P, DeFelici M, The cytoskeleton of the myenteric neurons during murine embryonic life. Anat Embryol (Berl). 1999 May;199(5):459-69 |
1 | J:174747 Franco SJ, Martinez-Garay I, Gil-Sanz C, Harkins-Perry SR, Muller U, Reelin regulates cadherin function via Dab1/Rap1 to control neuronal migration and lamination in the neocortex. Neuron. 2011 Feb 10;69(3):482-97 |
1* | J:315590 Fujiwara K, Hasegawa K, Oka M, Yoneda Y, Yoshikawa K, Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system. Genes Cells. 2016 Nov;21(11):1176-1194 |
1* | J:190090 Hasegawa S, Kume H, Iinuma S, Yamasaki M, Takahashi N, Fukui T, Acetoacetyl-CoA synthetase is essential for normal neuronal development. Biochem Biophys Res Commun. 2012 Oct 19;427(2):398-403 |
1 | J:287499 Hattori Y, Naito Y, Tsugawa Y, Nonaka S, Wake H, Nagasawa T, Kawaguchi A, Miyata T, Transient microglial absence assists postmigratory cortical neurons in proper differentiation. Nat Commun. 2020 Apr 2;11(1):1631 |
1 | J:122204 Imai F, Hirai S, Akimoto K, Koyama H, Miyata T, Ogawa M, Noguchi S, Sasaoka T, Noda T, Ohno S, Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex. Development. 2006 May;133(9):1735-44 |
1 | J:314290 Kanemitsu Y, Fujitani M, Fujita Y, Zhang S, Su YQ, Kawahara Y, Yamashita T, The RNA-binding protein MARF1 promotes cortical neurogenesis through its RNase activity domain. Sci Rep. 2017 Apr 25;7(1):1155 |
1* | J:109511 Kimura I, Konishi M, Miyake A, Fujimoto M, Itoh N, Neudesin, a secreted factor, promotes neural cell proliferation and neuronal differentiation in mouse neural precursor cells. J Neurosci Res. 2006 Jun;83(8):1415-24 |
1 | J:316266 Martin-Ibanez R, Crespo E, Esgleas M, Urban N, Wang B, Waclaw R, Georgopoulos K, Martinez S, Campbell K, Vicario-Abejon C, Alberch J, Chan S, Kastner P, Rubenstein JL, Canals JM, Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons. Stem Cells Dev. 2012 Aug 10;21(12):2239-51 |
1 | J:240536 Martin-Ibanez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Garcia-Diaz Barriga G, Edel MJ, Vicario-Abejon C, Alberch J, Girault JA, Chan S, Kastner P, Canals JM, Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017 Apr 15;144(8):1566-1577 |
1 | J:118055 Mingorance-Le Meur A, Zheng B, Soriano E, del Rio JA, Involvement of the Myelin-associated inhibitor Nogo-A in early cortical development and neuronal maturation. Cereb Cortex. 2007 Oct;17(10):2375-86 |
1 | J:34807 Miyata T, Nakajima K, Aruga J, Takahashi S, Ikenaka K, Mikoshiba K, Ogawa M, Distribution of a reeler gene-related antigen in the developing cerebellum: an immunohistochemical study with an allogeneic antibody CR-50 on normal and reeler mice. J Comp Neurol. 1996 Aug 19;372(2):215-28 |
1* | J:25502 Ogawa M, Miyata T, Nakajima K, Yagyu K, Seike M, Ikenaka K, Yamamoto H, Mikoshiba K, The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons. Neuron. 1995 MAY;14(5):899-912 |
1 | J:187391 Pacal M, Bremner R, Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Dev Dyn. 2012 Oct;241(10):1525-44 |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
1 | J:50400 Rice DS, Sheldon M, D'Arcangelo G, Nakajima K, Goldowitz D, Curran T, Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain. Development. 1998 Sep;125(18):3719-29 |
1 | J:183605 Sakai D, Dixon J, Dixon MJ, Trainor PA, Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells. PLoS Genet. 2012 Mar;8(3):e1002566 |
1 | J:228291 Shinmyo Y, Asrafuzzaman Riyadh M, Ahmed G, Bin Naser I, Hossain M, Takebayashi H, Kawasaki H, Ohta K, Tanaka H, Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex. Nat Commun. 2015;6:10232 |
1 | J:74020 Soriano E, Del Rio JA, Martinez A, Super H, Organization of the embryonic and early postnatal murine hippocampus. I. Immunocytochemical characterization of neuronal populations in the subplate and marginal zone. J Comp Neurol. 1994 Apr 22;342(4):571-95 |
1* | J:82445 Talamillo A, Quinn JC, Collinson JM, Caric D, Price DJ, West JD, Hill RE, Pax6 regulates regional development and neuronal migration in the cerebral cortex. Dev Biol. 2003 Mar 1;255(1):151-63 |
1 | J:333324 Tominaga K, Sakashita E, Kasashima K, Kuroiwa K, Nagao Y, Iwamori N, Endo H, Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells. Int J Mol Sci. 2023 Jan 20;24(3) |
1 | J:341968 Weber AI, Parthasarathy S, Borisova E, Epifanova E, Preussner M, Rusanova A, Ambrozkiewicz MC, Bessa P, Newman AG, Muller L, Schaal H, Heyd F, Tarabykin V, Srsf1 and Elavl1 act antagonistically on neuronal fate choice in the developing neocortex by controlling TrkC receptor isoform expression. Nucleic Acids Res. 2023 Oct 27;51(19):10218-10237 |
2 | J:116689 Yamashita N, Uchida Y, Ohshima T, Hirai S, Nakamura F, Taniguchi M, Mikoshiba K, Honnorat J, Kolattukudy P, Thomasset N, Takei K, Takahashi T, Goshima Y, Collapsin response mediator protein 1 mediates reelin signaling in cortical neuronal migration. J Neurosci. 2006 Dec 20;26(51):13357-62 |
1 | J:251744 Zega K, Jovanovic VM, Vitic Z, Niedzielska M, Knaapi L, Jukic MM, Partanen J, Friedel RF, Lang R, Brodski C, Dusp16 Deficiency Causes Congenital Obstructive Hydrocephalus and Brain Overgrowth by Expansion of the Neural Progenitor Pool. Front Mol Neurosci. 2017;10:372 |
1 | J:271709 Zheng C, Chen D, Zhang Y, Bai Y, Huang S, Zheng D, Liang W, She S, Peng X, Wang P, Mo X, Song Q, Lv P, Huang J, Ye RD, Wang Y, FAM19A1 is a new ligand for GPR1 that modulates neural stem-cell proliferation and differentiation. FASEB J. 2018 May 25;:fj201800020RRR |
Map2k1 mitogen-activated protein kinase kinase 1 (Synonyms: MAP kinase kinase 1, Mek1, Prkmk1) | |
Results | Reference |
1 | J:154797 Cho KW, Cai J, Kim HY, Hosoya A, Ohshima H, Choi KY, Jung HS, ERK activation is involved in tooth development via FGF10 signaling. J Exp Zool B Mol Dev Evol. 2009 Dec 15;312(8):901-11 |
1* | J:131397 Cho KW, Cho SW, Lee JM, Lee MJ, Gang HS, Jung HS, Expression of phosphorylated forms of ERK, MEK, PTEN and PI3K in mouse oral development. Gene Expr Patterns. 2008 Apr;8(4):284-290 |
1 | J:173779 Kossler N, Stricker S, Rodelsperger C, Robinson PN, Kim J, Dietrich C, Osswald M, Kuhnisch J, Stevenson DA, Braun T, Mundlos S, Kolanczyk M, Neurofibromin (Nf1) is required for skeletal muscle development. Hum Mol Genet. 2011 Jul 15;20(14):2697-709 |
1* | J:301228 Laugel-Haushalter V, Langer A, Marrie J, Fraulob V, Schuhbaur B, Koch-Phillips M, Dolle P, Bloch-Zupan A, From the transcription of genes involved in ectodermal dysplasias to the understanding of associated dental anomalies. Mol Syndromol. 2012 Oct;3(4):158-68 |
1 | J:221658 Vithayathil J, Pucilowska J, Goodnough LH, Atit RP, Landreth GE, Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation. J Neurosci. 2015 Apr 29;35(17):6836-48 |
Map2k2 mitogen-activated protein kinase kinase 2 (Synonyms: MAP kinase/Erk kinase, MEK2, Prkmk2) | |
Results | Reference |
1 | J:154797 Cho KW, Cai J, Kim HY, Hosoya A, Ohshima H, Choi KY, Jung HS, ERK activation is involved in tooth development via FGF10 signaling. J Exp Zool B Mol Dev Evol. 2009 Dec 15;312(8):901-11 |
1* | J:131397 Cho KW, Cho SW, Lee JM, Lee MJ, Gang HS, Jung HS, Expression of phosphorylated forms of ERK, MEK, PTEN and PI3K in mouse oral development. Gene Expr Patterns. 2008 Apr;8(4):284-290 |
1 | J:221658 Vithayathil J, Pucilowska J, Goodnough LH, Atit RP, Landreth GE, Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation. J Neurosci. 2015 Apr 29;35(17):6836-48 |
Map2k3 mitogen-activated protein kinase kinase 3 (Synonyms: MAP kinase kinase 3, MKK3, Prkmk3) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
Map2k4 mitogen-activated protein kinase kinase 4 (Synonyms: JNKK1, MKK4, Sek1, Serk1) | |
Results | Reference |
1* | J:51597 Nishina H, Vaz C, Billia P, Nghiem M, Sasaki T, De la Pompa JL, Furlonger K, Paige C, Hui C, Fischer KD, Kishimoto H, Iwatsubo T, Katada T, Woodgett JR, Penninger JM, Defective liver formation and liver cell apoptosis in mice lacking the stress signaling kinase SEK1/MKK4. Development. 1999 Feb;126(3):505-16 |
Map2k6 mitogen-activated protein kinase kinase 6 (Synonyms: MAP kinase kinase 6, MKK6, Prkmk6, SAPKK3) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Map2k7 mitogen-activated protein kinase kinase 7 (Synonyms: 5930412N11Rik, Jnkk2, MAP kinase kinase 7, MKK7, Prkmk7, sek2) | |
Results | Reference |
1* | J:44734 Yao Z, Diener K, Wang XS, Zukowski M, Matsumoto G, Zhou G, Mo R, Sasaki T, Nishina H, Hui CC, Tan TH, Woodgett JP, Penninger JM, Activation of stress-activated protein kinases/c-Jun N-terminal protein kinases (SAPKs/JNKs) by a novel mitogen-activated protein kinase kinase. J Biol Chem. 1997 Dec 19;272(51):32378-83 |
Map3k1 mitogen-activated protein kinase kinase kinase 1 (Synonyms: lg, Mekk, MEKK1) | |
Results | Reference |
1 | J:216505 Meng Q, Mongan M, Wang J, Tang X, Zhang J, Kao W, Xia Y, Epithelial sheet movement requires the cooperation of c-Jun and MAP3K1. Dev Biol. 2014 Nov 1;395(1):29-37 |
Map3k4 mitogen-activated protein kinase kinase kinase 4 (Synonyms: D17Rp17, D17Rp17e, MAPKKK4, Mekk4, mKIAA0213, MTK1, RP17, Tas, T-associated sex reversal) | |
Results | Reference |
1 | J:231463 Haque K, Pandey AK, Zheng HW, Riazuddin S, Sha SH, Puligilla C, MEKK4 Signaling Regulates Sensory Cell Development and Function in the Mouse Inner Ear. J Neurosci. 2016 Jan 27;36(4):1347-61 |
1* | J:117267 Sarkisian MR, Bartley CM, Chi H, Nakamura F, Hashimoto-Torii K, Torii M, Flavell RA, Rakic P, MEKK4 signaling regulates filamin expression and neuronal migration. Neuron. 2006 Dec 7;52(5):789-801 |
Map3k7 mitogen-activated protein kinase kinase kinase 7 (Synonyms: Tak1, TAK1, TGF-beta activated kinase 1, transforming growth factor beta-activated kinase 1, transforming growth factor-beta-activated kinase 1) | |
Results | Reference |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1* | J:317359 Sakamachi Y, Morioka S, Mihaly SR, Takaesu G, Foley JF, Fessler MB, Ninomiya-Tsuji J, TAK1 regulates resident macrophages by protecting lysosomal integrity. Cell Death Dis. 2017 Feb 9;8(2):e2598 |
1 | J:150837 Shim JH, Greenblatt MB, Xie M, Schneider MD, Zou W, Zhai B, Gygi S, Glimcher LH, TAK1 is an essential regulator of BMP signalling in cartilage. EMBO J. 2009 Jul 22;28(14):2028-41 |
1 | J:278336 Wang W, Chun H, Baek J, Sadik JE, Shirazyan A, Razavi P, Lopez N, Lyons KM, The TGFbeta type I receptor TGFbetaRI functions as an inhibitor of BMP signaling in cartilage. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15570-15579 |
1 | J:232056 Yu J, Zhang F, Wang S, Zhang Y, Fan M, Xu Z, TAK1 is activated by TGF-beta signaling and controls axonal growth during brain development. J Mol Cell Biol. 2014 Aug;6(4):349-51 |
Map3k12 mitogen-activated protein kinase kinase kinase 12 (Synonyms: DLK, MUK, Zpk) | |
Results | Reference |
2 | J:157201 Eto K, Kawauchi T, Osawa M, Tabata H, Nakajima K, Role of dual leucine zipper-bearing kinase (DLK/MUK/ZPK) in axonal growth. Neurosci Res. 2010 Jan;66(1):37-45 |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
Map4k1 mitogen-activated protein kinase kinase kinase kinase 1 (Synonyms: Hpk1) | |
Results | Reference |
1* | J:37543 Kiefer F, Tibbles LA, Anafi M, Janssen A, Zanke BW, Lassam N, Pawson T, Woodgett JR, Iscove NN, HPK1, a hematopoietic protein kinase activating the SAPK/JNK pathway. EMBO J. 1996 Dec 16;15(24):7013-25 |
Map7 microtubule-associated protein 7 (Synonyms: E-MAP-115, mshi, mste, Mtap7, ste) | |
Results | Reference |
1* | J:49733 Fabre-Jonca N, Allaman JM, Radlgruber G, Meda P, Kiss JZ, French LE, Masson D, The distribution of murine 115-kDa epithelial microtubule-associated protein (E-MAP-115) during embryogenesis and in adult organs suggests a role in epithelial polarization and differentiation. Differentiation. 1998 Aug;63(4):169-80 |
Mapk1 mitogen-activated protein kinase 1 (Synonyms: 9030612K14Rik, Erk2, MAPK2, p42mapk, Prkm1) | |
Results | Reference |
1 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1 | J:112971 Camarero G, Tyrsin OY, Xiang C, Pfeiffer V, Pleiser S, Wiese S, Gotz R, Rapp UR, Cortical migration defects in mice expressing A-RAF from the B-RAF locus. Mol Cell Biol. 2006 Oct;26(19):7103-15 |
1 | J:196836 Cammas L, Wolfe J, Choi SY, Dedhar S, Beggs HE, Integrin-linked kinase deletion in the developing lens leads to capsule rupture, impaired fiber migration and non-apoptotic epithelial cell death. Invest Ophthalmol Vis Sci. 2012;53(6):3067-81 |
1 | J:154797 Cho KW, Cai J, Kim HY, Hosoya A, Ohshima H, Choi KY, Jung HS, ERK activation is involved in tooth development via FGF10 signaling. J Exp Zool B Mol Dev Evol. 2009 Dec 15;312(8):901-11 |
1* | J:131397 Cho KW, Cho SW, Lee JM, Lee MJ, Gang HS, Jung HS, Expression of phosphorylated forms of ERK, MEK, PTEN and PI3K in mouse oral development. Gene Expr Patterns. 2008 Apr;8(4):284-290 |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1 | J:102162 Cicero S, Herrup K, Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci. 2005 Oct 19;25(42):9658-68 |
2 | J:206944 Clegg JM, Conway CD, Howe KM, Price DJ, Mason JO, Turnbull JE, Basson MA, Pratt T, Heparan sulfotransferases Hs6st1 and Hs2st Keep Erk in check for mouse corpus callosum development. J Neurosci. 2014 Feb 5;34(6):2389-401 |
1 | J:104802 Deckelbaum RA, Majithia A, Booker T, Henderson JE, Loomis CA, The homeoprotein engrailed 1 has pleiotropic functions in calvarial intramembranous bone formation and remodeling. Development. 2006 Jan;133(1):63-74 |
2 | J:232897 Fremin C, Saba-El-Leil MK, Levesque K, Ang SL, Meloche S, Functional Redundancy of ERK1 and ERK2 MAP Kinases during Development. Cell Rep. 2015 Aug 11;12(6):913-21 |
1* | J:161097 Gauthier-Fisher A, Lin DC, Greeve M, Kaplan DR, Rottapel R, Miller FD, Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells. Nat Neurosci. 2009 Jun;12(6):735-44 |
1 | J:139005 Geske MJ, Zhang X, Patel KK, Ornitz DM, Stappenbeck TS, Fgf9 signaling regulates small intestinal elongation and mesenchymal development. Development. 2008 Sep;135(17):2959-68 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
1 | J:259186 Heng X, Guo Q, Leung AW, Li JY, Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6:e23253 |
1 | J:242713 Ikeda Y, Zabbarova I, Schaefer CM, Bushnell D, De Groat WC, Kanai A, Bates CM, Fgfr2 is integral for bladder mesenchyme patterning and function. Am J Physiol Renal Physiol. 2017 Apr 01;312(4):F607-F618 |
1 | J:216228 Inoue S, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y, New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet. 2014 Dec 15;23(24):6553-66 |
1* | J:203480 Koyama N, Hayashi T, Mizukoshi K, Matsumoto T, Gresik EW, Kashimata M, Extracellular regulated kinase5 is expressed in fetal mouse submandibular glands and is phosphorylated in response to epidermal growth factor and other ligands of the ErbB family of receptors. Dev Growth Differ. 2012 Dec;54(9):801-8 |
1* | J:238086 Kusano R, Fujita K, Shinoda Y, Nagaura Y, Kiyonari H, Abe T, Watanabe T, Matsui Y, Fukaya M, Sakagami H, Sato T, Funahashi JI, Ohnishi M, Tamura S, Kobayashi T, Targeted disruption of the mouse protein phosphatase ppm1l gene leads to structural abnormalities in the brain. FEBS Lett. 2016 Oct;590(20):3606-3615 |
1 | J:310318 Li H, Tao C, Cai Z, Hertzler-Schaefer K, Collins TN, Wang F, Feng GS, Gotoh N, Zhang X, Frs2alpha and Shp2 signal independently of Gab to mediate FGF signaling in lens development. J Cell Sci. 2014 Feb 1;127(Pt 3):571-82 |
1* | J:257228 Li S, Pan Y, Differential expression of transforming growth factor-beta1, connective tissue growth factor, phosphorylated-SMAD2/3 and phosphorylated-ERK1/2 during mouse tooth development. J Mol Histol. 2017 Dec;48(5-6):347-355 |
1 | J:326547 Lu P, Wang P, Wu B, Wang Y, Liu Y, Cheng W, Feng X, Yuan X, Atteya MM, Ferro H, Sugi Y, Rydquist G, Esmaily M, Butcher JT, Chang CP, Lenz J, Zheng D, Zhou B, A SOX17-PDGFB signaling axis regulates aortic root development. Nat Commun. 2022 Jul 13;13(1):4065 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1 | J:171515 Muller PS, Schulz R, Maretto S, Costello I, Srinivas S, Bikoff E, Robertson E, The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis. Development. 2011 Apr;138(7):1297-308 |
1 | J:318016 Otani S, Kakinuma S, Kamiya A, Goto F, Kaneko S, Miyoshi M, Tsunoda T, Asano Y, Kawai-Kitahata F, Nitta S, Nakata T, Okamoto R, Itsui Y, Nakagawa M, Azuma S, Asahina Y, Yamaguchi T, Koshikawa N, Seiki M, Nakauchi H, Watanabe M, Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells. Biochem Biophys Res Commun. 2016 Jan 22;469(4):1062-8 |
1 | J:158679 Pan Y, Carbe C, Powers A, Feng GS, Zhang X, Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development. Development. 2010 Apr;137(7):1085-93 |
1 | J:246653 Park JC, Jeong WJ, Kim MY, Min D, Choi KY, Retinoic-acid-mediated HRas stabilization induces neuronal differentiation of neural stem cells during brain development. J Cell Sci. 2016 Aug 01;129(15):2997-3007 |
1 | J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088 |
1 | J:137882 Samuels IS, Karlo JC, Faruzzi AN, Pickering K, Herrup K, Sweatt JD, Saitta SC, Landreth GE, Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function. J Neurosci. 2008 Jul 2;28(27):6983-95 |
1 | J:186876 Sugiyama N, Tsukiyama T, Yamaguchi TP, Yokoyama T, The canonical Wnt signaling pathway is not involved in renal cyst development in the kidneys of inv mutant mice. Kidney Int. 2011 May;79(9):957-65 |
1 | J:354182 Sun M, Gao Y, Li Z, Yang L, Liu G, Xu Z, Guo R, You Y, Yang Z, ERK signaling expands mammalian cortical radial glial cells and extends the neurogenic period. Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2314802121 |
1* | J:168653 Sylvestersen KB, Herrera PL, Serup P, Rescan C, Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):105-11 |
1 | J:225743 Um SH, Sticker-Jantscheff M, Chau GC, Vintersten K, Mueller M, Gangloff YG, Adams RH, Spetz JF, Elghazi L, Pfluger PT, Pende M, Bernal-Mizrachi E, Tauler A, Tschop MH, Thomas G, Kozma SC, S6K1 controls pancreatic beta cell size independently of intrauterine growth restriction. J Clin Invest. 2015 Jul 1;125(7):2736-47 |
1 | J:221658 Vithayathil J, Pucilowska J, Goodnough LH, Atit RP, Landreth GE, Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation. J Neurosci. 2015 Apr 29;35(17):6836-48 |
1 | J:99501 Wang J, Ito T, Udaka N, Okudela K, Yazawa T, Kitamura H, PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung. Tissue Cell. 2005 Feb;37(1):25-35 |
2 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:345586 Wazin F, Lovicu FJ, Conditional Ablation of Spred1 and Spred2 in the Eye Lens Negatively Impacts Its Development and Growth. Cells. 2024 Feb 6;13(4) |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
2 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
1 | J:242341 Zhang J, Upadhya D, Lu L, Reneker LW, Fibroblast growth factor receptor 2 (FGFR2) is required for corneal epithelial cell proliferation and differentiation during embryonic development. PLoS One. 2015;10(1):e0117089 |
1 | J:348286 Zhang Z, Wu Y, Fu J, Yu X, Su Y, Jia S, Cheng H, Shen Y, He X, Ren K, Zheng X, Guan H, Rao F, Zhao L, Proteostatic reactivation of the developmental transcription factor TBX3 drives BRAF/MAPK-mediated tumorigenesis. Nat Commun. 2024 May 15;15(1):4108 |
Mapk3 mitogen-activated protein kinase 3 (Synonyms: Erk-1, Erk1, Esrk1, Mtap2k, p44erk1, p44mapk, p44 MAP kinase, Prkm3) | |
Results | Reference |
1 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1 | J:196836 Cammas L, Wolfe J, Choi SY, Dedhar S, Beggs HE, Integrin-linked kinase deletion in the developing lens leads to capsule rupture, impaired fiber migration and non-apoptotic epithelial cell death. Invest Ophthalmol Vis Sci. 2012;53(6):3067-81 |
1 | J:154797 Cho KW, Cai J, Kim HY, Hosoya A, Ohshima H, Choi KY, Jung HS, ERK activation is involved in tooth development via FGF10 signaling. J Exp Zool B Mol Dev Evol. 2009 Dec 15;312(8):901-11 |
1* | J:131397 Cho KW, Cho SW, Lee JM, Lee MJ, Gang HS, Jung HS, Expression of phosphorylated forms of ERK, MEK, PTEN and PI3K in mouse oral development. Gene Expr Patterns. 2008 Apr;8(4):284-290 |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
2 | J:206944 Clegg JM, Conway CD, Howe KM, Price DJ, Mason JO, Turnbull JE, Basson MA, Pratt T, Heparan sulfotransferases Hs6st1 and Hs2st Keep Erk in check for mouse corpus callosum development. J Neurosci. 2014 Feb 5;34(6):2389-401 |
1 | J:104802 Deckelbaum RA, Majithia A, Booker T, Henderson JE, Loomis CA, The homeoprotein engrailed 1 has pleiotropic functions in calvarial intramembranous bone formation and remodeling. Development. 2006 Jan;133(1):63-74 |
1* | J:161097 Gauthier-Fisher A, Lin DC, Greeve M, Kaplan DR, Rottapel R, Miller FD, Lfc and Tctex-1 regulate the genesis of neurons from cortical precursor cells. Nat Neurosci. 2009 Jun;12(6):735-44 |
1 | J:139005 Geske MJ, Zhang X, Patel KK, Ornitz DM, Stappenbeck TS, Fgf9 signaling regulates small intestinal elongation and mesenchymal development. Development. 2008 Sep;135(17):2959-68 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
1 | J:259186 Heng X, Guo Q, Leung AW, Li JY, Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6:e23253 |
1 | J:242713 Ikeda Y, Zabbarova I, Schaefer CM, Bushnell D, De Groat WC, Kanai A, Bates CM, Fgfr2 is integral for bladder mesenchyme patterning and function. Am J Physiol Renal Physiol. 2017 Apr 01;312(4):F607-F618 |
1 | J:216228 Inoue S, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y, New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet. 2014 Dec 15;23(24):6553-66 |
1* | J:203480 Koyama N, Hayashi T, Mizukoshi K, Matsumoto T, Gresik EW, Kashimata M, Extracellular regulated kinase5 is expressed in fetal mouse submandibular glands and is phosphorylated in response to epidermal growth factor and other ligands of the ErbB family of receptors. Dev Growth Differ. 2012 Dec;54(9):801-8 |
1* | J:238086 Kusano R, Fujita K, Shinoda Y, Nagaura Y, Kiyonari H, Abe T, Watanabe T, Matsui Y, Fukaya M, Sakagami H, Sato T, Funahashi JI, Ohnishi M, Tamura S, Kobayashi T, Targeted disruption of the mouse protein phosphatase ppm1l gene leads to structural abnormalities in the brain. FEBS Lett. 2016 Oct;590(20):3606-3615 |
1 | J:340406 Lai Y, Guo Y, Liao C, Mao C, Liu J, Ren C, Yang W, Luo L, Chen W, Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development. Sci Rep. 2023 Sep 13;13(1):15170 |
1 | J:310318 Li H, Tao C, Cai Z, Hertzler-Schaefer K, Collins TN, Wang F, Feng GS, Gotoh N, Zhang X, Frs2alpha and Shp2 signal independently of Gab to mediate FGF signaling in lens development. J Cell Sci. 2014 Feb 1;127(Pt 3):571-82 |
1* | J:257228 Li S, Pan Y, Differential expression of transforming growth factor-beta1, connective tissue growth factor, phosphorylated-SMAD2/3 and phosphorylated-ERK1/2 during mouse tooth development. J Mol Histol. 2017 Dec;48(5-6):347-355 |
1 | J:326547 Lu P, Wang P, Wu B, Wang Y, Liu Y, Cheng W, Feng X, Yuan X, Atteya MM, Ferro H, Sugi Y, Rydquist G, Esmaily M, Butcher JT, Chang CP, Lenz J, Zheng D, Zhou B, A SOX17-PDGFB signaling axis regulates aortic root development. Nat Commun. 2022 Jul 13;13(1):4065 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1 | J:171515 Muller PS, Schulz R, Maretto S, Costello I, Srinivas S, Bikoff E, Robertson E, The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis. Development. 2011 Apr;138(7):1297-308 |
1 | J:318016 Otani S, Kakinuma S, Kamiya A, Goto F, Kaneko S, Miyoshi M, Tsunoda T, Asano Y, Kawai-Kitahata F, Nitta S, Nakata T, Okamoto R, Itsui Y, Nakagawa M, Azuma S, Asahina Y, Yamaguchi T, Koshikawa N, Seiki M, Nakauchi H, Watanabe M, Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells. Biochem Biophys Res Commun. 2016 Jan 22;469(4):1062-8 |
1 | J:158679 Pan Y, Carbe C, Powers A, Feng GS, Zhang X, Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development. Development. 2010 Apr;137(7):1085-93 |
1 | J:246653 Park JC, Jeong WJ, Kim MY, Min D, Choi KY, Retinoic-acid-mediated HRas stabilization induces neuronal differentiation of neural stem cells during brain development. J Cell Sci. 2016 Aug 01;129(15):2997-3007 |
1 | J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088 |
1 | J:137882 Samuels IS, Karlo JC, Faruzzi AN, Pickering K, Herrup K, Sweatt JD, Saitta SC, Landreth GE, Deletion of ERK2 mitogen-activated protein kinase identifies its key roles in cortical neurogenesis and cognitive function. J Neurosci. 2008 Jul 2;28(27):6983-95 |
1 | J:186876 Sugiyama N, Tsukiyama T, Yamaguchi TP, Yokoyama T, The canonical Wnt signaling pathway is not involved in renal cyst development in the kidneys of inv mutant mice. Kidney Int. 2011 May;79(9):957-65 |
1 | J:354182 Sun M, Gao Y, Li Z, Yang L, Liu G, Xu Z, Guo R, You Y, Yang Z, ERK signaling expands mammalian cortical radial glial cells and extends the neurogenic period. Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2314802121 |
1* | J:168653 Sylvestersen KB, Herrera PL, Serup P, Rescan C, Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):105-11 |
1 | J:225743 Um SH, Sticker-Jantscheff M, Chau GC, Vintersten K, Mueller M, Gangloff YG, Adams RH, Spetz JF, Elghazi L, Pfluger PT, Pende M, Bernal-Mizrachi E, Tauler A, Tschop MH, Thomas G, Kozma SC, S6K1 controls pancreatic beta cell size independently of intrauterine growth restriction. J Clin Invest. 2015 Jul 1;125(7):2736-47 |
1 | J:221658 Vithayathil J, Pucilowska J, Goodnough LH, Atit RP, Landreth GE, Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation. J Neurosci. 2015 Apr 29;35(17):6836-48 |
1 | J:99501 Wang J, Ito T, Udaka N, Okudela K, Yazawa T, Kitamura H, PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung. Tissue Cell. 2005 Feb;37(1):25-35 |
2 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:345586 Wazin F, Lovicu FJ, Conditional Ablation of Spred1 and Spred2 in the Eye Lens Negatively Impacts Its Development and Growth. Cells. 2024 Feb 6;13(4) |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
2 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
1 | J:242341 Zhang J, Upadhya D, Lu L, Reneker LW, Fibroblast growth factor receptor 2 (FGFR2) is required for corneal epithelial cell proliferation and differentiation during embryonic development. PLoS One. 2015;10(1):e0117089 |
1 | J:348286 Zhang Z, Wu Y, Fu J, Yu X, Su Y, Jia S, Cheng H, Shen Y, He X, Ren K, Zheng X, Guan H, Rao F, Zhao L, Proteostatic reactivation of the developmental transcription factor TBX3 drives BRAF/MAPK-mediated tumorigenesis. Nat Commun. 2024 May 15;15(1):4108 |
Mapk4 mitogen-activated protein kinase 4 (Synonyms: A330097D03Rik, Erk3-related, p63Mapk) | |
Results | Reference |
1* | J:180468 Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, Gaestel M, Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5. J Biol Chem. 2006 Nov 17;281(46):35511-9 |
Mapk6 mitogen-activated protein kinase 6 (Synonyms: 2610021I23Rik, D130053K17Rik, Erk3, ERK3, Mapk4, Mapk63, Prkm4, Prkm6) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:180468 Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, Gaestel M, Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5. J Biol Chem. 2006 Nov 17;281(46):35511-9 |
Mapk7 mitogen-activated protein kinase 7 (Synonyms: b2b2346Clo, big MAP kinase 1, BMK1, ERK5, Erk5-T) | |
Results | Reference |
1* | J:203480 Koyama N, Hayashi T, Mizukoshi K, Matsumoto T, Gresik EW, Kashimata M, Extracellular regulated kinase5 is expressed in fetal mouse submandibular glands and is phosphorylated in response to epidermal growth factor and other ligands of the ErbB family of receptors. Dev Growth Differ. 2012 Dec;54(9):801-8 |
1 | J:183463 Zou J, Pan YW, Wang Z, Chang SY, Wang W, Wang X, Tournier C, Storm DR, Xia Z, Targeted deletion of ERK5 MAP kinase in the developing nervous system impairs development of GABAergic interneurons in the main olfactory bulb and behavioral discrimination between structurally similar odorants. J Neurosci. 2012 Mar 21;32(12):4118-32 |
Mapk8 mitogen-activated protein kinase 8 (Synonyms: c-Jun N-terminal kinase, JNK1, Prkm8) | |
Results | Reference |
1 | J:313612 Arimura N, Okada M, Taya S, Dewa KI, Tsuzuki A, Uetake H, Miyashita S, Hashizume K, Shimaoka K, Egusa S, Nishioka T, Yanagawa Y, Yamakawa K, Inoue YU, Inoue T, Kaibuchi K, Hoshino M, DSCAM regulates delamination of neurons in the developing midbrain. Sci Adv. 2020 Sep;6(36) |
1 | J:175562 Cho IH, Lee KW, Ha HY, Han PL, JNK/stress-activated protein kinase associated protein 1 is required for early development of telencephalic commissures in embryonic brains. Exp Mol Med. 2011 Aug 31;43(8):462-70 |
1 | J:231463 Haque K, Pandey AK, Zheng HW, Riazuddin S, Sha SH, Puligilla C, MEKK4 Signaling Regulates Sensory Cell Development and Function in the Mouse Inner Ear. J Neurosci. 2016 Jan 27;36(4):1347-61 |
1* | J:238086 Kusano R, Fujita K, Shinoda Y, Nagaura Y, Kiyonari H, Abe T, Watanabe T, Matsui Y, Fukaya M, Sakagami H, Sato T, Funahashi JI, Ohnishi M, Tamura S, Kobayashi T, Targeted disruption of the mouse protein phosphatase ppm1l gene leads to structural abnormalities in the brain. FEBS Lett. 2016 Oct;590(20):3606-3615 |
1 | J:167714 Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, Chen H, Haneline LS, Chan RJ, Schwartz RJ, Field LJ, Atkinson SJ, Shou W, Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development. 2011 Jan;138(2):303-15 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1 | J:318016 Otani S, Kakinuma S, Kamiya A, Goto F, Kaneko S, Miyoshi M, Tsunoda T, Asano Y, Kawai-Kitahata F, Nitta S, Nakata T, Okamoto R, Itsui Y, Nakagawa M, Azuma S, Asahina Y, Yamaguchi T, Koshikawa N, Seiki M, Nakauchi H, Watanabe M, Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells. Biochem Biophys Res Commun. 2016 Jan 22;469(4):1062-8 |
1 | J:177905 Yamasaki T, Kawasaki H, Arakawa S, Shimizu K, Shimizu S, Reiner O, Okano H, Nishina S, Azuma N, Penninger JM, Katada T, Nishina H, Stress-Activated Protein Kinase MKK7 Regulates Axon Elongation in the Developing Cerebral Cortex. J Neurosci. 2011 Nov 16;31(46):16872-16883 |
1 | J:316215 Zhou N, Li N, Liu J, Wang Y, Gao J, Wu Y, Chen X, Liu C, Xiao J, Persistent Wnt/beta-catenin signaling in mouse epithelium induces the ectopic Dspp expression in cheek mesenchyme. Organogenesis. 2019;15(1):1-12 |
Mapk9 mitogen-activated protein kinase 9 (Synonyms: c-Jun N-terminal kinase, JNK2, JNK/SAPK alpha, Prkm9) | |
Results | Reference |
1 | J:163484 Lin MH, Chang KW, Lin SC, Miner JH, Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling. Dev Biol. 2010 Aug 15;344(2):707-19 |
Mapk12 mitogen-activated protein kinase 12 (Synonyms: Erk6, P38gamma, Prkm12, Sapk3) | |
Results | Reference |
1 | J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005 |
Mapk14 mitogen-activated protein kinase 14 (Synonyms: Crk1, Csbp1, CSBP2, Mxi2, p38, p38a, p38 alpha, p38-alpha, p38alpha, p38 MAPK, p38MAPK, p38 MAP Kinase, p38 MAP kinase alpha) | |
Results | Reference |
1 | J:166615 Chang Z, Zhang Q, Feng Q, Xu J, Teng T, Luan Q, Shan C, Hu Y, Hemmings BA, Gao X, Yang Z, Deletion of Akt1 causes heart defects and abnormal cardiomyocyte proliferation. Dev Biol. 2010 Nov 15;347(2):384-91 |
1 | J:332407 Gu Y, Zhou Y, Ju S, Liu X, Zhang Z, Guo J, Gao J, Zang J, Sun H, Chen Q, Wang J, Xu J, Xu Y, Chen Y, Guo Y, Dai J, Ma H, Wang C, Jin G, Li C, Xia Y, Shen H, Yang Y, Guo X, Hu Z, Multi-omics profiling visualizes dynamics of cardiac development and functions. Cell Rep. 2022 Dec 27;41(13):111891 |
2 | J:196581 Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G, The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-beta signaling. Dev Biol. 2013 May 15;377(2):415-27 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:216228 Inoue S, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y, New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet. 2014 Dec 15;23(24):6553-66 |
1* | J:238086 Kusano R, Fujita K, Shinoda Y, Nagaura Y, Kiyonari H, Abe T, Watanabe T, Matsui Y, Fukaya M, Sakagami H, Sato T, Funahashi JI, Ohnishi M, Tamura S, Kobayashi T, Targeted disruption of the mouse protein phosphatase ppm1l gene leads to structural abnormalities in the brain. FEBS Lett. 2016 Oct;590(20):3606-3615 |
1 | J:340406 Lai Y, Guo Y, Liao C, Mao C, Liu J, Ren C, Yang W, Luo L, Chen W, Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development. Sci Rep. 2023 Sep 13;13(1):15170 |
1 | J:163484 Lin MH, Chang KW, Lin SC, Miner JH, Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling. Dev Biol. 2010 Aug 15;344(2):707-19 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1 | J:97328 Nishio S, Hatano M, Nagata M, Horie S, Koike T, Tokuhisa T, Mochizuki T, Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation. J Clin Invest. 2005 Apr 1;115(4):910-918 |
1 | J:318016 Otani S, Kakinuma S, Kamiya A, Goto F, Kaneko S, Miyoshi M, Tsunoda T, Asano Y, Kawai-Kitahata F, Nitta S, Nakata T, Okamoto R, Itsui Y, Nakagawa M, Azuma S, Asahina Y, Yamaguchi T, Koshikawa N, Seiki M, Nakauchi H, Watanabe M, Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells. Biochem Biophys Res Commun. 2016 Jan 22;469(4):1062-8 |
1 | J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088 |
1 | J:316215 Zhou N, Li N, Liu J, Wang Y, Gao J, Wu Y, Chen X, Liu C, Xiao J, Persistent Wnt/beta-catenin signaling in mouse epithelium induces the ectopic Dspp expression in cheek mesenchyme. Organogenesis. 2019;15(1):1-12 |
Mapkapk5 MAP kinase-activated protein kinase 5 (Synonyms: MK5, PRAK) | |
Results | Reference |
1* | J:180468 Kant S, Schumacher S, Singh MK, Kispert A, Kotlyarov A, Gaestel M, Characterization of the atypical MAPK ERK4 and its activation of the MAPK-activated protein kinase MK5. J Biol Chem. 2006 Nov 17;281(46):35511-9 |
Mapt microtubule-associated protein tau (Synonyms: Mtapt, Tau) | |
Results | Reference |
1 | J:311814 Eom TY, Stanco A, Guo J, Wilkins G, Deslauriers D, Yan J, Monckton C, Blair J, Oon E, Perez A, Salas E, Oh A, Ghukasyan V, Snider WD, Rubenstein JL, Anton ES, Differential regulation of microtubule severing by APC underlies distinct patterns of projection neuron and interneuron migration. Dev Cell. 2014 Dec 22;31(6):677-89 |
1 | J:165476 Keimpema E, Barabas K, Morozov YM, Tortoriello G, Torii M, Cameron G, Yanagawa Y, Watanabe M, Mackie K, Harkany T, Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding. J Neurosci. 2010 Oct 20;30(42):13992-4007 |
1* | J:127447 Kwiatkowski AV, Rubinson DA, Dent EW, Edward van Veen J, Leslie JD, Zhang J, Mebane LM, Philippar U, Pinheiro EM, Burds AA, Bronson RT, Mori S, Fassler R, Gertler FB, Ena/VASP Is Required for neuritogenesis in the developing cortex. Neuron. 2007 Nov 8;56(3):441-55 |
1 | J:158918 Renier N, Schonewille M, Giraudet F, Badura A, Tessier-Lavigne M, Avan P, De Zeeuw CI, Chedotal A, Genetic dissection of the function of hindbrain axonal commissures. PLoS Biol. 2010;8(3):e1000325 |
1 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
Marchf7 membrane associated ring-CH-type finger 7 (Synonyms: Axot, Gtrgeo17, March7) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Marco macrophage receptor with collagenous structure (Synonyms: Scara2) | |
Results | Reference |
2 | J:269295 Kang TB, Jeong JS, Yang SH, Kovalenko A, Wallach D, Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3. Cell Death Differ. 2018 Jun;25(6):1107-1117 |
Marf1 meiosis regulator and mRNA stability 1 (Synonyms: 4921513D23Rik, MGC:36956) | |
Results | Reference |
1 | J:314290 Kanemitsu Y, Fujitani M, Fujita Y, Zhang S, Su YQ, Kawahara Y, Yamashita T, The RNA-binding protein MARF1 promotes cortical neurogenesis through its RNase activity domain. Sci Rep. 2017 Apr 25;7(1):1155 |
Mark1 MAP/microtubule affinity regulating kinase 1 (Synonyms: B930025N23Rik, Emk3) | |
Results | Reference |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
Mark2 MAP/microtubule affinity regulating kinase 2 (Synonyms: Emk, Par-1) | |
Results | Reference |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1 | J:140256 Hartleben B, Schweizer H, Lubben P, Bartram MP, Moller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB, Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. J Biol Chem. 2008 Aug 22;283(34):23033-8 |
Mark3 MAP/microtubule affinity regulating kinase 3 (Synonyms: 1600015G02Rik, A430080F22Rik, C-TAK1, ETK-1, mKIAA1860) | |
Results | Reference |
2 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1 | J:140256 Hartleben B, Schweizer H, Lubben P, Bartram MP, Moller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB, Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. J Biol Chem. 2008 Aug 22;283(34):23033-8 |
Mark4 MAP/microtubule affinity regulating kinase 4 (Synonyms: 2410090P21Rik, Markl1) | |
Results | Reference |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
Mars1 methionine-tRNA synthetase 1 (Synonyms: Mars, methionine tRNA ligase, methionyl-tRNA synthetase, MetRS) | |
Results | Reference |
1 | J:342871 Xiang J, Pompetti AJ, Faranda AP, Wang Y, Novo SG, Li DW, Duncan MK, ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment. Cells. 2023 Nov 16;12(22) |
Mas1 MAS1 oncogene (Synonyms: Mas-1, MasR, Mas receptor) | |
Results | Reference |
1* | J:218046 Cuffe JS, Walton SL, Steane SE, Singh RR, Simmons DG, Moritz KM, The effects of gestational age and maternal hypoxia on the placental renin angiotensin system in the mouse. Placenta. 2014 Nov;35(11):953-61 |
3* | J:237726 Wang L, Liang J, Leung PS, The ACE2/Ang-(1-7)/Mas Axis Regulates the Development of Pancreatic Endocrine Cells in Mouse Embryos. PLoS One. 2015;10(6):e0128216 |
Masp1 MBL associated serine protease 1 (Synonyms: Crarf) | |
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1* | J:99055 Liu Y, Endo Y, Homma S, Kanno K, Yaginuma H, Fujita T, Ficolin A and ficolin B are expressed in distinct ontogenic patterns and cell types in the mouse. Mol Immunol. 2005 Jul;42(11):1265-73 |
Masp2 MBL associated serine protease 2 (Synonyms: MAp19, MASP-2) | |
Results | Reference |
1* | J:99055 Liu Y, Endo Y, Homma S, Kanno K, Yaginuma H, Fujita T, Ficolin A and ficolin B are expressed in distinct ontogenic patterns and cell types in the mouse. Mol Immunol. 2005 Jul;42(11):1265-73 |
Mast1 microtubule associated serine/threonine kinase 1 (Synonyms: 9430008B02Rik, SAST, SAST170) | |
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2 | J:268904 Tripathy R, Leca I, van Dijk T, Weiss J, van Bon BW, Sergaki MC, Gstrein T, Breuss M, Tian G, Bahi-Buisson N, Paciorkowski AR, Pagnamenta AT, Wenninger-Weinzierl A, Martinez-Reza MF, Landler L, Lise S, Taylor JC, Terrone G, Vitiello G, Del Giudice E, Brunetti-Pierri N, D'Amico A, Reymond A, Voisin N, Bernstein JA, Farrelly E, Kini U, Leonard TA, Valence S, Burglen L, Armstrong L, Hiatt SM, Cooper GM, Aldinger KA, Dobyns WB, Mirzaa G, Pierson TM, Baas F, Chelly J, Cowan NJ, Keays DA, Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations. Neuron. 2018 Dec 19;100(6):1354-1368.e5 |
Mat1a methionine adenosyltransferase 1A (Synonyms: AdoMet, Ams, MAT, MATA1, SAMS, SAMS1) | |
Results | Reference |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
Matn1 matrilin 1, cartilage matrix protein (Synonyms: CMP, Crtm, Mat1, matrilin-1) | |
Results | Reference |
2* | J:32849 Aszodi A, Hauser N, Studer D, Paulsson M, Hiripi L, Bosze Z, Cloning, sequencing and expression analysis of mouse cartilage matrix protein cDNA. Eur J Biochem. 1996 Mar 15;236(3):970-7 |
1 | J:148688 Kahn J, Shwartz Y, Blitz E, Krief S, Sharir A, Breitel DA, Rattenbach R, Relaix F, Maire P, Rountree RB, Kingsley DM, Zelzer E, Muscle contraction is necessary to maintain joint progenitor cell fate. Dev Cell. 2009 May;16(5):734-43 |
1 | J:91587 Mates L, Nicolae C, Morgelin M, Deak F, Kiss I, Aszodi A, Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities. Matrix Biol. 2004 Jun;23(3):195-204 |
1 | J:170582 Mundy C, Yasuda T, Kinumatsu T, Yamaguchi Y, Iwamoto M, Enomoto-Iwamoto M, Koyama E, Pacifici M, Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine. Dev Biol. 2011 Mar 1;351(1):70-81 |
1 | J:112002 van der Weyden L, Wei L, Luo J, Yang X, Birk DE, Adams DJ, Bradley A, Chen Q, Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis. Am J Pathol. 2006 Aug;169(2):515-27 |
Matn2 matrilin 2 (Synonyms: Crtm2) | |
Results | Reference |
1 | J:91587 Mates L, Nicolae C, Morgelin M, Deak F, Kiss I, Aszodi A, Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities. Matrix Biol. 2004 Jun;23(3):195-204 |
1 | J:112002 van der Weyden L, Wei L, Luo J, Yang X, Birk DE, Adams DJ, Bradley A, Chen Q, Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis. Am J Pathol. 2006 Aug;169(2):515-27 |
Matn3 matrilin 3 | |
Results | Reference |
1 | J:91587 Mates L, Nicolae C, Morgelin M, Deak F, Kiss I, Aszodi A, Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities. Matrix Biol. 2004 Jun;23(3):195-204 |
Matn4 matrilin 4 (Synonyms: matrilin-4) | |
Results | Reference |
1 | J:91587 Mates L, Nicolae C, Morgelin M, Deak F, Kiss I, Aszodi A, Mice lacking the extracellular matrix adaptor protein matrilin-2 develop without obvious abnormalities. Matrix Biol. 2004 Jun;23(3):195-204 |
Matr3 matrin 3 (Synonyms: 1110061A14Rik, 2810017I02Rik, D030046F20Rik, mKIAA0723) | |
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1* | J:220876 Quintero-Rivera F, Xi QJ, Keppler-Noreuil KM, Lee JH, Higgins AW, Anchan RM, Roberts AE, Seong IS, Fan X, Lage K, Lu LY, Tao J, Hu X, Berezney R, Gelb BD, Kamp A, Moskowitz IP, Lacro RV, Lu W, Morton CC, Gusella JF, Maas RL, MATR3 disruption in human and mouse associated with bicuspid aortic valve, aortic coarctation and patent ductus arteriosus. Hum Mol Genet. 2015 Apr 15;24(8):2375-89 |
Maz MYC-associated zinc finger protein (purine-binding transcription factor) (Synonyms: Pur-1, PUR1, SAF-1, SAF-2) | |
Results | Reference |
1* | J:325107 Cao X, Yan Y, Luo X, Yang X, Cui H, Yang Y, Li H, Analyses of the circadian clock genes expression in whole embryos and maternal major tissues of mice. J Mol Histol. 2022 Apr;53(2):473-482 |
1* | J:257647 Haller M, Au J, O'Neill M, Lamb DJ, 16p11.2 transcription factor MAZ is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):E1849-E1858 |
Mb myoglobin | |
Results | Reference |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
Mbd3 methyl-CpG binding domain protein 3 | |
Results | Reference |
1 | J:222255 Knock E, Pereira J, Lombard PD, Dimond A, Leaford D, Livesey FJ, Hendrich B, The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex. Neural Dev. 2015;10:13 |
Mbnl1 muscleblind like splicing regulator 1 (Synonyms: mKIAA0428) | |
Results | Reference |
2* | J:85713 Kanadia RN, Urbinati CR, Crusselle VJ, Luo D, Lee YJ, Harrison JK, Oh SP, Swanson MS, Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3. Gene Expr Patterns. 2003 Aug;3(4):459-62 |
Mbnl2 muscleblind like splicing factor 2 (Synonyms: 1110002M11Rik) | |
Results | Reference |
2* | J:85713 Kanadia RN, Urbinati CR, Crusselle VJ, Luo D, Lee YJ, Harrison JK, Oh SP, Swanson MS, Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3. Gene Expr Patterns. 2003 Aug;3(4):459-62 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Mbnl3 muscleblind like splicing factor 3 (Synonyms: A530038J18Rik, CHCR, E430034C16Rik) | |
Results | Reference |
2* | J:85713 Kanadia RN, Urbinati CR, Crusselle VJ, Luo D, Lee YJ, Harrison JK, Oh SP, Swanson MS, Developmental expression of mouse muscleblind genes Mbnl1, Mbnl2 and Mbnl3. Gene Expr Patterns. 2003 Aug;3(4):459-62 |
Mbp myelin basic protein (Synonyms: golli-mbp, Hmbpr, jve) | |
Results | Reference |
1 | J:212081 Dai ZM, Sun S, Wang C, Huang H, Hu X, Zhang Z, Lu QR, Qiu M, Stage-specific regulation of oligodendrocyte development by Wnt/beta-catenin signaling. J Neurosci. 2014 Jun 18;34(25):8467-73 |
1* | J:74236 Fu H, Qi Y, Tan M, Cai J, Takebayashi H, Nakafuku M, Richardson W, Qiu M, Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation. Development. 2002 Feb;129(3):681-93 |
1 | J:288683 Gacem N, Kavo A, Zerad L, Richard L, Mathis S, Kapur RP, Parisot M, Amiel J, Dufour S, de la Grange P, Pingault V, Vallat JM, Bondurand N, ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. Nat Commun. 2020 Jan 10;11(1):198 |
1 | J:44046 Landry CF, Ellison J, Skinner E, Campagnoni AT, Golli-MBP proteins mark the earliest stages of fiber extension and terminal arboration in the mouse peripheral nervous system. J Neurosci Res. 1997 Oct 15;50(2):265-71 |
1 | J:177840 Magri L, Cambiaghi M, Cominelli M, Alfaro-Cervello C, Cursi M, Pala M, Bulfone A, Garcia-Verdugo JM, Leocani L, Minicucci F, Poliani PL, Galli R, Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions. Cell Stem Cell. 2011 Nov 4;9(5):447-62 |
1* | J:119850 Oh S, Huang X, Chiang C, Specific requirements of sonic hedgehog signaling during oligodendrocyte development. Dev Dyn. 2005 Nov;234(3):489-96 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1* | J:84432 Qi Y, Tan M, Hui CC, Qiu M, Gli2 is required for normal Shh signaling and oligodendrocyte development in the spinal cord. Mol Cell Neurosci. 2003 Jul;23(3):440-50 |
1 | J:74258 Stolt CC, Rehberg S, Ader M, Lommes P, Riethmacher D, Schachner M, Bartsch U, Wegner M, Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev. 2002 Jan 15;16(2):165-70 |
1* | J:98585 Stolt CC, Schmitt S, Lommes P, Sock E, Wegner M, Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord. Dev Biol. 2005 May 15;281(2):309-17 |
1 | J:107228 Sun T, Hafler BP, Kaing S, Kitada M, Ligon KL, Widlund HR, Yuk DI, Stiles CD, Rowitch DH, Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube. Dev Biol. 2006 Apr 1;292(1):152-64 |
1* | J:337458 Waldhauser V, Baroti T, Frob F, Wegner M, PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12) |
1* | J:288669 Wedel M, Frob F, Elsesser O, Wittmann MT, Lie DC, Reis A, Wegner M, Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation. Nucleic Acids Res. 2020 May 21;48(9):4839-4857 |
1 | J:105927 Wu S, Wu Y, Capecchi MR, Motoneurons and oligodendrocytes are sequentially generated from neural stem cells but do not appear to share common lineage-restricted progenitors in vivo. Development. 2006 Feb;133(4):581-90 |
1 | J:152576 Ye F, Chen Y, Hoang T, Montgomery RL, Zhao XH, Bu H, Hu T, Taketo MM, van Es JH, Clevers H, Hsieh J, Bassel-Duby R, Olson EN, Lu QR, HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci. 2009 Jul;12(7):829-38 |
1 | J:208340 Zhu Q, Zhao X, Zheng K, Li H, Huang H, Zhang Z, Mastracci T, Wegner M, Chen Y, Sussel L, Qiu M, Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS. Development. 2014 Feb;141(3):548-55 |
Mc2r melanocortin 2 receptor (Synonyms: Acthr, adrenocorticotropic hormone receptor) | |
Results | Reference |
2* | J:168512 Simard M, Cote M, Provost PR, Tremblay Y, Expression of genes related to the hypothalamic-pituitary-adrenal axis in murine fetal lungs in late gestation. Reprod Biol Endocrinol. 2010;8:134 |
Mc4r melanocortin 4 receptor (Synonyms: Fatboy, Pkcp) | |
Results | Reference |
1* | J:308824 de Guia RM, Hassing AS, Ma T, Plucinska K, Holst B, Gerhart-Hines Z, Emanuelli B, Treebak JT, Ablation of Nampt in AgRP neurons leads to neurodegeneration and impairs fasting- and ghrelin-mediated food intake. FASEB J. 2021 May;35(5):e21450 |
Mcam melanoma cell adhesion molecule (Synonyms: 1-gicerin, CD146, Muc18, s-endo, s-gicerin) | |
Results | Reference |
1 | J:362029 Anjum H, Smith JP, Martini AG, Yacu GS, Medrano S, Gomez RA, Sequeira-Lopez MLS, Quaggin SE, Finer G, Tcf21 as a founder transcription factor in specifying Foxd1 cells to the juxtaglomerular cell lineage. Am J Physiol Renal Physiol. 2025 Jan 1;328(1):F121-F130 |
2* | J:229257 Gu Z, Imai F, Kim IJ, Fujita H, Katayama Ki, Mori K, Yoshihara Y, Yoshida Y, Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550 |
1 | J:292237 Roostalu U, Aldeiri B, Albertini A, Humphreys N, Simonsen-Jackson M, Wong JKF, Cossu G, Distinct Cellular Mechanisms Underlie Smooth Muscle Turnover in Vascular Development and Repair. Circ Res. 2018 Jan 19;122(2):267-281 |
Mcf2 mcf.2 transforming sequence (Synonyms: B230117G22Rik, Dbl) | |
Results | Reference |
1 | J:196361 Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnani MG, Messina G, Cossu G, Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory. Dev Cell. 2013 Mar 25;24(6):586-99 |
Mcf2l mcf.2 transforming sequence-like (Synonyms: C130040G20Rik, Dbs, mKIAA0362) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Mcidas multiciliate differentiation and DNA synthesis associated cell cycle protein (Synonyms: Gm6320, Idas, Mci, Mcin, multicilin) | |
Results | Reference |
1* | J:230806 Arbi M, Pefani DE, Kyrousi C, Lalioti ME, Kalogeropoulou A, Papanastasiou AD, Taraviras S, Lygerou Z, GemC1 controls multiciliogenesis in the airway epithelium. EMBO Rep. 2016 Mar;17(3):400-13 |
2* | J:310453 Kyrousi C, Arbi M, Pilz GA, Pefani DE, Lalioti ME, Ninkovic J, Gotz M, Lygerou Z, Taraviras S, Mcidas and GemC1 are key regulators for the generation of multiciliated ependymal cells in the adult neurogenic niche. Development. 2015 Nov 1;142(21):3661-74 |
Mcm2 minichromosome maintenance complex component 2 (Synonyms: BM28, CDCL1, Mcmd2, mKIAA0030) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
1 | J:241853 Parisot J, Flore G, Bertacchi M, Studer M, COUP-TFI mitotically regulates production and migration of dentate granule cells and modulates hippocampal Cxcr4 expression. Development. 2017 Jun 01;144(11):2045-2058 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
1* | J:337458 Waldhauser V, Baroti T, Frob F, Wegner M, PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12) |
Mcm3 minichromosome maintenance complex component 3 (Synonyms: Mcmd, P1, p1.m) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
1 | J:227638 Alvarez S, Diaz M, Flach J, Rodriguez-Acebes S, Lopez-Contreras AJ, Martinez D, Canamero M, Fernandez-Capetillo O, Isern J, Passegue E, Mendez J, Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality. Nat Commun. 2015;6:8548 |
Mcm5 minichromosome maintenance complex component 5 (Synonyms: Cdc46, mCD46, Mcmd5) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Mcm6 minichromosome maintenance complex component 6 (Synonyms: D1Wsu22e, Mcmd6) | |
Results | Reference |
1* | J:132131 Barton KM, Levine EM, Expression patterns and cell cycle profiles of PCNA, MCM6, cyclin D1, cyclin A2, cyclin B1, and phosphorylated histone H3 in the developing mouse retina. Dev Dyn. 2008 Mar;237(3):672-82 |
Mcm7 minichromosome maintenance complex component 7 (Synonyms: mCDC47, Mcmd7) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Mcph1 microcephaly, primary autosomal recessive 1 (Synonyms: 5430437K10Rik, BRIT1, D030046N04Rik) | |
Results | Reference |
2 | J:304136 Journiac N, Gilabert-Juan J, Cipriani S, Benit P, Liu X, Jacquier S, Faivre V, Delahaye-Duriez A, Csaba Z, Hourcade T, Melinte E, Lebon S, Violle-Poirsier C, Oury JF, Adle-Biassette H, Wang ZQ, Mani S, Rustin P, Gressens P, Nardelli J, Cell Metabolic Alterations due to Mcph1 Mutation in Microcephaly. Cell Rep. 2020 Apr 14;31(2):107506 |
Mctp1 multiple C2 domains, transmembrane 1 (Synonyms: 2810465F10Rik) | |
Results | Reference |
1* | J:264553 Tarchini B, Longo-Guess C, Tian C, Tadenev ALD, Devanney N, Johnson KR, A spontaneous mouse deletion in Mctp1 uncovers a long-range cis-regulatory region crucial for NR2F1 function during inner ear development. Dev Biol. 2018 Nov 15;443(2):153-164 |
Mdfi MyoD family inhibitor (Synonyms: I-mf, I-mfa) | |
Results | Reference |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Mdfic MyoD family inhibitor domain containing (Synonyms: clone 1.5, Kdt1) | |
Results | Reference |
1 | J:326462 Byrne AB, Brouillard P, Sutton DL, Kazenwadel J, Montazaribarforoushi S, Secker GA, Oszmiana A, Babic M, Betterman KL, Brautigan PJ, White M, Piltz SG, Thomas PQ, Hahn CN, Rath M, Felbor U, Korenke GC, Smith CL, Wood KH, Sheppard SE, Adams DM, Kariminejad A, Helaers R, Boon LM, Revencu N, Moore L, Barnett C, Haan E, Arts P, Vikkula M, Scott HS, Harvey NL, Pathogenic variants in MDFIC cause recessive central conducting lymphatic anomaly with lymphedema. Sci Transl Med. 2022 Mar 2;14(634):eabm4869 |
Mdga1 MAM domain containing glycosylphosphatidylinositol anchor 1 (Synonyms: 1200011I03Rik, Mamdc3) | |
Results | Reference |
2* | J:166980 Ishikawa T, Gotoh N, Murayama C, Abe T, Iwashita M, Matsuzaki F, Suzuki T, Yamamoto T, IgSF molecule MDGA1 is involved in radial migration and positioning of a subset of cortical upper-layer neurons. Dev Dyn. 2011 Jan;240(1):96-107 |
1* | J:108383 Takeuchi A, O'Leary DD, Radial migration of superficial layer cortical neurons controlled by novel Ig cell adhesion molecule MDGA1. J Neurosci. 2006 Apr 26;26(17):4460-4 |
Mdh1 malate dehydrogenase 1, NAD (soluble) (Synonyms: B230377B03Rik, MDH-s, Mor-2, Mor2) | |
Results | Reference |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
Mdk midkine (Synonyms: Mek, MK) | |
Results | Reference |
1* | J:276701 Cui R, Lwigale P, Expression of the heparin-binding growth factors Midkine and pleiotrophin during ocular development. Gene Expr Patterns. 2019 Jun;32:28-37 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:216228 Inoue S, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y, New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet. 2014 Dec 15;23(24):6553-66 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
2 | J:81588 Kaplan F, Comber J, Sladek R, Hudson TJ, Muglia LJ, Macrae T, Gagnon S, Asada M, Brewer JA, Sweezey NB, The growth factor midkine is modulated by both glucocorticoid and retinoid in fetal lung development. Am J Respir Cell Mol Biol. 2003 Jan;28(1):33-41 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:139147 Mitsiadis TA, Caton J, De Bari C, Bluteau G, The large functional spectrum of the heparin-binding cytokines MK and HB-GAM in continuously growing organs: the rodent incisor as a model. Dev Biol. 2008 Aug 1;320(1):256-66 |
2* | J:24148 Mitsiadis TA, Muramatsu T, Muramatsu H, Thesleff I, Midkine (MK), a heparin-binding growth/differentiation factor, is regulated by retinoic acid and epithelial-mesenchymal interactions in the developing mouse tooth, and affects cell proliferation and morphogenesis. J Cell Biol. 1995 Apr;129(1):267-81 |
2* | J:22554 Mitsiadis TA, Salmivirta M, Muramatsu T, Muramatsu H, Rauvala H, Lehtonen E, Jalkanen M, Thesleff I, Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis. Development. 1995 Jan;121(1):37-51 |
1 | J:95925 Park YK, Franklin JL, Settle SH, Levy SE, Chung E, Jeyakumar LH, Shyr Y, Washington MK, Whitehead RH, Aronow BJ, Coffey RJ, Gene expression profile analysis of mouse colon embryonic development. Genesis. 2005 Jan;41(1):1-12 |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
Mdm2 transformed mouse 3T3 cell double minute 2 (Synonyms: 1700007J15Rik, Mdm-2) | |
Results | Reference |
1 | J:160518 Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, Jenkins RB, Tihan T, Vandenberg SR, James CD, Tanaka K, Taylor MD, Weiss WA, Chesler L, Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010 May 15;24(10):1059-72 |
Mdm4 transformed mouse 3T3 cell double minute 4 (Synonyms: 4933417N07Rik, Mdmx) | |
Results | Reference |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
Mecom MDS1 and EVI1 complex locus (Synonyms: D630039M04Rik, Evi-1, Evi1, Jbo, Mds1, MDS1-EVI1, Prdm3, ZNFPR1B1) | |
Results | Reference |
1 | J:310868 Backx E, Wauters E, Baldan J, Van Bulck M, Michiels E, Heremans Y, De Paep DL, Kurokawa M, Goyama S, Bouwens L, Jacquemin P, Houbracken I, Rooman I, MECOM permits pancreatic acinar cell dedifferentiation avoiding cell death under stress conditions. Cell Death Differ. 2021 Sep;28(9):2601-2615 |
1 | J:354192 He H, Bell SM, Davis AK, Zhao S, Sridharan A, Na CL, Guo M, Xu Y, Snowball J, Swarr DT, Zacharias WJ, Whitsett JA, PRDM3/16 regulate chromatin accessibility required for NKX2-1 mediated alveolar epithelial differentiation and function. Nat Commun. 2024 Sep 16;15(1):8112 |
1 | J:164806 Nagamachi A, Htun PW, Ma F, Miyazaki K, Yamasaki N, Kanno M, Inaba T, Honda Z, Okuda T, Oda H, Tsuji K, Honda H, A 5' untranslated region containing the IRES element in the Runx1 gene is required for angiogenesis, hematopoiesis and leukemogenesis in a knock-in mouse model. Dev Biol. 2010 Sep 15;345(2):226-36 |
1 | J:113445 Parkinson N, Hardisty-Hughes, Tateossian H, Tsai HT, Brooker D, Morse S, Lalane Z, MacKenzie F, Fray M, Glenister P, Woodward AM, Polley S, Barbaric I, Dear N, Hough TA, Hunter AJ, Cheeseman MT, Brown SD, Mutation at the Evi1 locus in Junbo mice causes susceptibility to Otitis media. PLoS Genet. 2006;2(10):e149 |
Mecp2 methyl CpG binding protein 2 (Synonyms: 1500041B07Rik, D630021H01Rik, Mbd5, WBP10) | |
Results | Reference |
3* | J:97538 Pelka GJ, Watson CM, Christodoulou J, Tam PP, Distinct expression profiles of Mecp2 transcripts with different lengths of 3'UTR in the brain and visceral organs during mouse development. Genomics. 2005 Apr;85(4):441-52 |
1* | J:142562 Rusconi L, Salvatoni L, Giudici L, Bertani I, Kilstrup-Nielsen C, Broccoli V, Landsberger N, CDKL5 expression is modulated during neuronal development and its subcellular distribution is tightly regulated by the C-terminal tail. J Biol Chem. 2008 Oct 31;283(44):30101-11 |
1* | J:74625 Shahbazian MD, Antalffy B, Armstrong DL, Zoghbi HY, Insight into Rett syndrome: MeCP2 levels display tissue- and cell-specific differences and correlate with neuronal maturation. Hum Mol Genet. 2002 Jan 15;11(2):115-24 |
Med1 mediator complex subunit 1 (Synonyms: CRSP210, DRIP205, l11Jus15, PBP, Pparbp, TRAP 220, TRAP220) | |
Results | Reference |
1 | J:143544 Cortellino S, Wang C, Wang B, Bassi MR, Caretti E, Champeval D, Calmont A, Jarnik M, Burch J, Zaret KS, Larue L, Bellacosa A, Defective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4. Dev Biol. 2009 Jan 1;325(1):225-37 |
1* | J:189008 Jia Y, Viswakarma N, Crawford SE, Sarkar J, Sambasiva Rao M, Karpus WJ, Kanwar YS, Zhu YJ, Reddy JK, Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. Mech Dev. 2012 Sep;129(9-12):193-207 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Med15 mediator complex subunit 15 (Synonyms: A230074L19Rik, Pcqap) | |
Results | Reference |
1* | J:355262 Kadhim AZ, Vanderkruk B, Mar S, Dan M, Zosel K, Xu EE, Spencer RJ, Sasaki S, Cheng X, Sproul SLJ, Speckmann T, Nian C, Cullen R, Shi R, Luciani DS, Hoffman BG, Taubert S, Lynn FC, Transcriptional coactivator MED15 is required for beta cell maturation. Nat Commun. 2024 Oct 8;15(1):8711 |
Med25 mediator complex subunit 25 (Synonyms: 2610034E13Rik, 2610529E18Rik, ESTM2) | |
Results | Reference |
1 | J:205660 Nakamura Y, Yamamoto K, He X, Otsuki B, Kim Y, Murao H, Soeda T, Tsumaki N, Deng JM, Zhang Z, Behringer RR, Crombrugghe Bd, Postlethwait JH, Warman ML, Nakamura T, Akiyama H, Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25. Nat Commun. 2011;2:251 |
Mef2a myocyte enhancer factor 2A (Synonyms: A430079H05Rik) | |
Results | Reference |
1 | J:119152 Arnold MA, Kim Y, Czubryt MP, Phan D, McAnally J, Qi X, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN, MEF2C transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell. 2007 Mar;12(3):377-89 |
1 | J:196361 Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnani MG, Messina G, Cossu G, Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory. Dev Cell. 2013 Mar 25;24(6):586-99 |
1* | J:18124 Edmondson DG, Lyons GE, Martin JF, Olson EN, Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis. Development. 1994 May;120(5):1251-63 |
1 | J:28136 Lyons GE, Micales BK, Schwarz J, Martin JF, Olson EN, Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturation. J Neurosci. 1995 Aug;15(8):5727-38 |
Mef2b myocyte enhancer factor 2B | |
Results | Reference |
1 | J:119152 Arnold MA, Kim Y, Czubryt MP, Phan D, McAnally J, Qi X, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN, MEF2C transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell. 2007 Mar;12(3):377-89 |
1 | J:28136 Lyons GE, Micales BK, Schwarz J, Martin JF, Olson EN, Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturation. J Neurosci. 1995 Aug;15(8):5727-38 |
1* | J:33568 Molkentin JD, Firulli AB, Black BL, Martin JF, Hustad CM, Copeland N, Jenkins N, Lyons G, Olson EN, MEF2B is a potent transactivator expressed in early myogenic lineages. Mol Cell Biol. 1996 Jul;16(7):3814-24 |
Mef2c myocyte enhancer factor 2C (Synonyms: 5430401D19Rik, 9930028G15Rik) | |
Results | Reference |
1 | J:119152 Arnold MA, Kim Y, Czubryt MP, Phan D, McAnally J, Qi X, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN, MEF2C transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell. 2007 Mar;12(3):377-89 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:126582 Cobos I, Borello U, Rubenstein JL, Dlx transcription factors promote migration through repression of axon and dendrite growth. Neuron. 2007 Jun 21;54(6):873-88 |
1* | J:18124 Edmondson DG, Lyons GE, Martin JF, Olson EN, Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis. Development. 1994 May;120(5):1251-63 |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1* | J:238480 He K, Hu J, Yu H, Wang L, Tang F, Gu J, Ge L, Wang H, Li S, Hu P, Jin Y, Serine/Threonine Kinase 40 (Stk40) Functions as a Novel Regulator of Skeletal Muscle Differentiation. J Biol Chem. 2017 Jan 06;292(1):351-360 |
1 | J:28136 Lyons GE, Micales BK, Schwarz J, Martin JF, Olson EN, Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturation. J Neurosci. 1995 Aug;15(8):5727-38 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1* | J:225478 Oliver PL, Chodroff RA, Gosal A, Edwards B, Cheung AF, Gomez-Rodriguez J, Elliot G, Garrett LJ, Lickiss T, Szele F, Green ED, Molnar Z, Ponting CP, Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype. Cereb Cortex. 2015 Oct;25(10):3572-85 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
Mef2d myocyte enhancer factor 2D | |
Results | Reference |
1 | J:119152 Arnold MA, Kim Y, Czubryt MP, Phan D, McAnally J, Qi X, Shelton JM, Richardson JA, Bassel-Duby R, Olson EN, MEF2C transcription factor controls chondrocyte hypertrophy and bone development. Dev Cell. 2007 Mar;12(3):377-89 |
1* | J:18124 Edmondson DG, Lyons GE, Martin JF, Olson EN, Mef2 gene expression marks the cardiac and skeletal muscle lineages during mouse embryogenesis. Development. 1994 May;120(5):1251-63 |
1 | J:28136 Lyons GE, Micales BK, Schwarz J, Martin JF, Olson EN, Expression of mef2 genes in the mouse central nervous system suggests a role in neuronal maturation. J Neurosci. 1995 Aug;15(8):5727-38 |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1* | J:281311 Nakano Y, Wiechert S, Banfi B, Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8 |
Meg3 maternally expressed 3 (Synonyms: 2900016C05Rik, 3110050O07Rik, 6330408G06Rik, D12Bwg1266e, Gtl2) | |
Results | Reference |
1 | J:218430 Kamimura S, Hatanaka Y, Hirasawa R, Matsumoto K, Oikawa M, Lee J, Matoba S, Mizutani E, Ogonuki N, Inoue K, Kohda T, Ishino F, Ogura A, Establishment of paternal genomic imprinting in mouse prospermatogonia analyzed by nuclear transfer. Biol Reprod. 2014 Nov;91(5):120 |
1* | J:299191 Kitazawa M, Hayashi S, Imamura M, Takeda S, Oishi Y, Kaneko-Ishino T, Ishino F, Deficiency and overexpression of Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Kagami-Ogata syndromes. Development. 2020 Sep 2;147(21):dev185918 |
1 | J:216177 Labialle S, Marty V, Bortolin-Cavaille ML, Hoareau-Osman M, Pradere JP, Valet P, Martin PG, Cavaille J, The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation. EMBO J. 2014 Oct 1;33(19):2216-30 |
1 | J:106101 Manji SS, Sorensen BS, Klockars T, Lam T, Hutchison W, Dahl HH, Molecular characterization and expression of maternally expressed gene 3 (Meg3/Gtl2) RNA in the mouse inner ear. J Neurosci Res. 2006 Feb 1;83(2):181-90 |
1* | J:105951 McLaughlin D, Vidaki M, Renieri E, Karagogeos D, Expression pattern of the maternally imprinted gene Gtl2 in the forebrain during embryonic development and adulthood. Gene Expr Patterns. 2006 Apr;6(4):394-9 |
1 | J:108133 Sekita Y, Wagatsuma H, Irie M, Kobayashi S, Kohda T, Matsuda J, Yokoyama M, Ogura A, Schuster-Gossler K, Gossler A, Ishino F, Kaneko-Ishino T, Aberrant regulation of imprinted gene expression in Gtl2lacZ mice. Cytogenet Genome Res. 2006;113(1-4):223-9 |
1* | J:166176 Zhou Y, Cheunsuchon P, Nakayama Y, Lawlor MW, Zhong Y, Rice KA, Zhang L, Zhang X, Gordon FE, Lidov HG, Bronson RT, Klibanski A, Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. Development. 2010 Aug;137(16):2643-52 |
Megf9 multiple EGF-like-domains 9 (Synonyms: 4933405H16Rik, Egfl5, mKIAA0818) | |
Results | Reference |
1* | J:118579 Brandt-Bohne U, Keene DR, White FA, Koch M, MEGF9: a novel transmembrane protein with a strong and developmentally regulated expression in the nervous system. Biochem J. 2007 Jan 15;401(2):447-57 |
Megf10 multiple EGF-like-domains 10 (Synonyms: 3000002B06Rik, LOC240312) | |
Results | Reference |
1 | J:290493 Peng YR, James RE, Yan W, Kay JN, Kolodkin AL, Sanes JR, Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch. Neuron. 2020 Feb 5;105(3):464-474.e6 |
Meiob meiosis specific with OB domains (Synonyms: 4930528F23Rik) | |
Results | Reference |
1 | J:325094 Guan Y, Lin H, Leu NA, Ruthel G, Fuchs SY, Busino L, Luo M, Wang PJ, SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination. Nucleic Acids Res. 2022 May 20;50(9):5129-5144 |
1 | J:203426 Souquet B, Abby E, Herve R, Finsterbusch F, Tourpin S, Le Bouffant R, Duquenne C, Messiaen S, Martini E, Bernardino-Sgherri J, Toth A, Habert R, Livera G, MEIOB targets single-strand DNA and is necessary for meiotic recombination. PLoS Genet. 2013;9(9):e1003784 |
Meioc meiosis specific with coiled-coil domain (Synonyms: Gm1564, LOC268491, LOC380729) | |
Results | Reference |
1* | J:231231 Abby E, Tourpin S, Ribeiro J, Daniel K, Messiaen S, Moison D, Guerquin J, Gaillard JC, Armengaud J, Langa F, Toth A, Martini E, Livera G, Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts. Nat Commun. 2016;7:10324 |
1* | J:242348 Soh YQS, Mikedis MM, Kojima M, Godfrey AK, de Rooij DG, Page DC, Meioc maintains an extended meiotic prophase I in mice. PLoS Genet. 2017 Apr;13(4):e1006704 |
Meiosin meiosis initiator (Synonyms: Bhmg1) | |
Results | Reference |
1* | J:290712 Ishiguro KI, Matsuura K, Tani N, Takeda N, Usuki S, Yamane M, Sugimoto M, Fujimura S, Hosokawa M, Chuma S, Ko MSH, Araki K, Niwa H, MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells. Dev Cell. 2020 Feb 24;52(4):429-445.e10 |
Meis1 Meis homeobox 1 (Synonyms: C530044H18Rik) | |
Results | Reference |
2 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
3 | J:308827 Kaiser K, Jang A, Kompanikova P, Lun MP, Prochazka J, Machon O, Dani N, Prochazkova M, Laurent B, Gyllborg D, van Amerongen R, Fame RM, Gupta S, Wu F, Barker RA, Bukova I, Sedlacek R, Kozmik Z, Arenas E, Lehtinen MK, Bryja V, MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus. Development. 2021 May 15;148(10):dev192054 |
1 | J:264268 Li J, Wang C, Zhang Z, Wen Y, An L, Liang Q, Xu Z, Wei S, Li W, Guo T, Liu G, Tao G, You Y, Du H, Fu Z, He M, Chen B, Campbell K, Alvarez-Buylla A, Rubenstein JL, Yang Z, Transcription Factors Sp8 and Sp9 Coordinately Regulate Olfactory Bulb Interneuron Development. Cereb Cortex. 2018 Sep 1;28(9):3278-3294 |
1* | J:221341 Lun MP, Johnson MB, Broadbelt KG, Watanabe M, Kang YJ, Chau KF, Springel MW, Malesz A, Sousa AM, Pletikos M, Adelita T, Calicchio ML, Zhang Y, Holtzman MJ, Lidov HG, Sestan N, Steen H, Monuki ES, Lehtinen MK, Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production. J Neurosci. 2015 Mar 25;35(12):4903-16 |
1 | J:257543 Owa T, Taya S, Miyashita S, Yamashita M, Adachi T, Yamada K, Yokoyama M, Aida S, Nishioka T, Inoue YU, Goitsuka R, Nakamura T, Inoue T, Kaibuchi K, Hoshino M, Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation. J Neurosci. 2018 Jan 31;38(5):1277-1294 |
1 | J:63180 Toresson H, Parmar M, Campbell K, Expression of meis and pbx genes and their protein products in the developing telencephalon: implications for regional differentiation. Mech Dev. 2000 Jun;94(1-2):183-7 |
1 | J:163859 Tucker ES, Lehtinen MK, Maynard T, Zirlinger M, Dulac C, Rawson N, Pevny L, Lamantia AS, Proliferative and transcriptional identity of distinct classes of neural precursors in the mammalian olfactory epithelium. Development. 2010 Aug 1;137(15):2471-81 |
1* | J:198293 Yamada T, Urano-Tashiro Y, Tanaka S, Akiyama H, Tashiro F, Involvement of crosstalk between Oct4 and Meis1a in neural cell fate decision. PLoS One. 2013;8(2):e56997 |
Meis2 Meis homeobox 2 (Synonyms: A430109D20Rik, Meis2, Mrg1, Stra10) | |
Results | Reference |
1 | J:221075 Dai M, Wang Y, Fang L, Irwin DM, Zhu T, Zhang J, Zhang S, Wang Z, Differential expression of Meis2, Mab21l2 and Tbx3 during limb development associated with diversification of limb morphology in mammals. PLoS One. 2014;9(8):e106100 |
1 | J:309450 Doeppner TR, Herz J, Bahr M, Tonchev AB, Stoykova A, Zbtb20 Regulates Developmental Neurogenesis in the Olfactory Bulb and Gliogenesis After Adult Brain Injury. Mol Neurobiol. 2019 Jan;56(1):567-582 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:331367 Roussel J, Larcher R, Sicard P, Bideaux P, Richard S, Marmigere F, Thireau J, The autism-associated Meis2 gene is necessary for cardiac baroreflex regulation in mice. Sci Rep. 2022 Nov 23;12(1):20150 |
2 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1 | J:52596 Toresson H, Mata de Urquiza A, Fagerstrom C, Perlmann T, Campbell K, Retinoids are produced by glia in the lateral ganglionic eminence and regulate striatal neuron differentiation. Development. 1999 Mar;126(6):1317-26 |
1 | J:63180 Toresson H, Parmar M, Campbell K, Expression of meis and pbx genes and their protein products in the developing telencephalon: implications for regional differentiation. Mech Dev. 2000 Jun;94(1-2):183-7 |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Memo1 mediator of cell motility 1 (Synonyms: 0610016J10Rik, D930048L02Rik) | |
Results | Reference |
1 | J:215101 Kondo S, Bottos A, Allegood JC, Masson R, Maurer FG, Genoud C, Kaeser P, Huwiler A, Murakami M, Spiegel S, Hynes NE, Memo has a novel role in S1P signaling and crucial for vascular development. PLoS One. 2014;9(4):e94114 |
Men1 multiple endocrine neoplasia 1 (Synonyms: menin) | |
Results | Reference |
1 | J:141158 Fontaniere S, Duvillie B, Scharfmann R, Carreira C, Wang ZQ, Zhang CX, Tumour suppressor menin is essential for development of the pancreatic endocrine cells. J Endocrinol. 2008 Nov;199(2):287-98 |
Meox1 mesenchyme homeobox 1 (Synonyms: D330041M02Rik, Mox-1, Mox1) | |
Results | Reference |
1* | J:3682 Candia AF, Hu J, Crosby J, Lalley PA, Noden D, Nadeau JH, Wright CV, Mox-1 and Mox-2 define a novel homeobox gene subfamily and are differentially expressed during early mesodermal patterning in mouse embryos. Development. 1992 Dec;116(4):1123-36 |
1* | J:36233 Larue L, Antos C, Butz S, Huber O, Delmas V, Dominis M, Kemler R, A role for cadherins in tissue formation. Development. 1996 Oct;122(10):3185-94 |
1 | J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005 |
Meox2 mesenchyme homeobox 2 (Synonyms: Gax, Mox-2, Mox2) | |
Results | Reference |
1* | J:295958 Neupane S, Adhikari N, Jung JK, An CH, Lee S, Jun JH, Kim JY, Lee Y, Sohn WJ, Kim JY, Regulation of mesenchymal signaling in palatal mucosa differentiation. Histochem Cell Biol. 2018 Feb;149(2):143-152 |
Mep1a meprin 1 alpha (Synonyms: Mep-1, Mep1, Mep-1a, meprin A alpha-subunit, meprin alpha) | |
Results | Reference |
2* | J:68362 Kumar JM, Bond JS, Developmental expression of meprin metalloprotease subunits in ICR and C3H/He mouse kidney and intestine in the embryo, postnatally and after weaning. Biochim Biophys Acta. 2001 Mar 19;1518(1-2):106-14 |
Mep1b meprin 1 beta (Synonyms: Mep-1b, meprin beta) | |
Results | Reference |
1* | J:68362 Kumar JM, Bond JS, Developmental expression of meprin metalloprotease subunits in ICR and C3H/He mouse kidney and intestine in the embryo, postnatally and after weaning. Biochim Biophys Acta. 2001 Mar 19;1518(1-2):106-14 |
Mepe matrix extracellular phosphoglycoprotein with ASARM motif (bone) (Synonyms: OF45) | |
Results | Reference |
3* | J:227060 Fujikawa K, Yokohama-Tamaki T, Morita T, Baba O, Qin C, Shibata S, An in situ hybridization study of perlecan, DMP1, and MEPE in developing condylar cartilage of the fetal mouse mandible and limb bud cartilage. Eur J Histochem. 2015;59(3):2553 |
Mest mesoderm specific transcript (Synonyms: Peg1) | |
Results | Reference |
1 | J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132 |
1 | J:313300 Mesman S, van Hooft JA, Smidt MP, Mest/Peg1 Is Essential for the Development and Maintenance of a SNc Neuronal Subset. Front Mol Neurosci. 2016;9:166 |
Met met proto-oncogene (Synonyms: c-Met, HGF receptor, Par4) | |
Results | Reference |
1* | J:74504 Amano O, Yamane A, Shimada M, Koshimizu U, Nakamura T, Iseki S, Hepatocyte growth factor is essential for migration of myogenic cells and promotes their proliferation during the early periods of tongue morphogenesis in mouse embryos. Dev Dyn. 2002 Mar;223(2):169-79 |
1* | J:120667 Bouzin C, Clotman F, Renauld JC, Lemaigre FP, Rousseau GG, The onecut transcription factor hepatocyte nuclear factor-6 controls B lymphopoiesis in fetal liver. J Immunol. 2003 Aug 1;171(3):1297-303 |
1 | J:283675 Comai G, Heude E, Mella S, Paisant S, Pala F, Gallardo M, Langa F, Kardon G, Gopalakrishnan S, Tajbakhsh S, A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle. Elife. 2019 Sep 19;8:e47460 |
1 | J:296619 Fan Y, Richelme S, Avazeri E, Audebert S, Helmbacher F, Dono R, Maina F, Tissue-Specific Gain of RTK Signalling Uncovers Selective Cell Vulnerability during Embryogenesis. PLoS Genet. 2015;11(9):e1005533 |
1 | J:164668 Gascon E, Gaillard S, Malapert P, Liu Y, Rodat-Despoix L, Samokhvalov IM, Delmas P, Helmbacher F, Maina F, Moqrich A, Hepatocyte growth factor-Met signaling is required for Runx1 extinction and peptidergic differentiation in primary nociceptive neurons. J Neurosci. 2010 Sep 15;30(37):12414-23 |
1* | J:85916 Ikari T, Hiraki A, Seki K, Sugiura T, Matsumoto K, Shirasuna K, Involvement of hepatocyte growth factor in branching morphogenesis of murine salivary gland. Dev Dyn. 2003 Oct;228(2):173-84 |
1 | J:289321 Jangphattananont N, Sato H, Imamura R, Sakai K, Terakado Y, Murakami K, Barker N, Oshima H, Oshima M, Takagi J, Kato Y, Yano S, Matsumoto K, Distinct Localization of Mature HGF from its Precursor Form in Developing and Repairing the Stomach. Int J Mol Sci. 2019 Jun 17;20(12):2955 |
2 | J:69135 Powell EM, Mars WM, Levitt P, Hepatocyte growth factor/scatter factor is a motogen for interneurons migrating from the ventral to dorsal telencephalon. Neuron. 2001 Apr;30(1):79-89 |
Metrn meteorin, glial cell differentiation regulator (Synonyms: 1810034B16Rik) | |
Results | Reference |
1* | J:90575 Nishino J, Yamashita K, Hashiguchi H, Fujii H, Shimazaki T, Hamada H, Meteorin: a secreted protein that regulates glial cell differentiation and promotes axonal extension. EMBO J. 2004 May 5;23(9):1998-2008 |
Metrnl meteorin, glial cell differentiation regulator-like (Synonyms: 9430048M07Rik) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
Mettl1 methyltransferase 1, tRNA methylguanosine (Synonyms: 2810012D02Rik) | |
Results | Reference |
2* | J:355649 Li Q, Jiang S, Lei K, Han H, Chen Y, Lin W, Xiong Q, Qi X, Gan X, Sheng R, Wang Y, Zhang Y, Ma J, Li T, Lin S, Zhou C, Chen D, Yuan Q, Metabolic rewiring during bone development underlies tRNA m7G-associated primordial dwarfism. J Clin Invest. 2024 Sep 10;134(20) |
Mettl3 methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit (Synonyms: 2310024F18Rik, M6A, Spo8) | |
Results | Reference |
1 | J:263687 Wang CX, Cui GS, Liu X, Xu K, Wang M, Zhang XX, Jiang LY, Li A, Yang Y, Lai WY, Sun BF, Jiang GB, Wang HL, Tong WM, Li W, Wang XJ, Yang YG, Zhou Q, METTL3-mediated m6A modification is required for cerebellar development. PLoS Biol. 2018 Jun;16(6):e2004880 |
1 | J:313628 Xi L, Carroll T, Matos I, Luo JD, Polak L, Pasolli HA, Jaffrey SR, Fuchs E, m6A RNA methylation impacts fate choices during skin morphogenesis. Elife. 2020 Aug 26;9:e56980 |
1 | J:331893 Yang J, Zhang L, Li Y, Chen M, Identifying key m(6)A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses. Front Genet. 2022;13:974357 |
Mettl14 methyltransferase 14, N6-adenosine-methyltransferase subunit (Synonyms: G430022H21Rik, mKIAA1627) | |
Results | Reference |
1 | J:356737 Zhou R, Wang Q, Zeng S, Liang Y, Wang D, METTL14-mediated N6-methyladenosine modification of Col17a1/Itgalpha6/Itgbeta4 governs epidermal homeostasis. J Dermatol Sci. 2023 Dec;112(3):138-147 |
Mex3a mex3 RNA binding family member A (Synonyms: 2700083E18Rik, Rkhd4) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Mfap2 microfibrillar-associated protein 2 (Synonyms: Magp) | |
Results | Reference |
1* | J:16038 Chen Y, Faraco J, Yin W, Germiller J, Francke U, Bonadio J, Structure, chromosomal localization, and expression pattern of the murine Magp gene. J Biol Chem. 1993 Dec 25;268(36):27381-9 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Mfap4 microfibrillar-associated protein 4 (Synonyms: 1110007F23Rik) | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
Mfap5 microfibrillar associated protein 5 (Synonyms: MAGP-2) | |
Results | Reference |
1 | J:307093 Amato CM, Yao HH, Developmental and sexual dimorphic atlas of the prenatal mouse external genitalia at the single-cell level. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2103856118 |
Mfge8 milk fat globule EGF and factor V/VIII domain containing (Synonyms: EGF/factor VIII, lactadherin, MFG-E8, Mfgm, SED1) | |
Results | Reference |
1* | J:237193 Chaboub LS, Manalo JM, Lee HK, Glasgow SM, Chen F, Kawasaki Y, Akiyama T, Kuo CT, Creighton CJ, Mohila CA, Deneen B, Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury. J Neurosci. 2016 Nov 23;36(47):11904-11917 |
1* | J:317244 Lee J, Choi BI, Park SY, An SY, Han J, Kim JH, Fetal hematopoietic stem cells express MFG-E8 during mouse embryogenesis. Exp Mol Med. 2015 Jul 24;47:e174 |
Mfn1 mitofusin 1 (Synonyms: 2310002F04Rik, 6330416C07Rik, D3Ertd265e, HR2) | |
Results | Reference |
1 | J:333326 Suh J, Kim NK, Shim W, Lee SH, Kim HJ, Moon E, Sesaki H, Jang JH, Kim JE, Lee YS, Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab. 2023 Feb 7;35(2):345-360.e7 |
Mfn2 mitofusin 2 (Synonyms: D630023P19Rik, Fzo, hypertension related protein 1) | |
Results | Reference |
1 | J:333326 Suh J, Kim NK, Shim W, Lee SH, Kim HJ, Moon E, Sesaki H, Jang JH, Kim JE, Lee YS, Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab. 2023 Feb 7;35(2):345-360.e7 |
2* | J:259679 Zhao J, Wu X, Wu D, Yu Y, Yu Y, Wang Y, Fu Q, Zhang J, Yao K, Embryonic Surface Ectoderm-specific Mitofusin 2 Conditional Knockout Induces Congenital Cataracts in Mice. Sci Rep. 2018 Jan 24;8(1):1522 |
Mfng MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (Synonyms: manic fringe) | |
Results | Reference |
1 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1 | J:63320 Favier B, Fliniaux I, Thelu J, Viallet JP, Demarchez M, Jahoda CA, Dhouailly D, Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators. Dev Dyn. 2000 Jul;218(3):426-37 |
1* | J:60388 Ishii Y, Nakamura S, Osumi N, Demarcation of early mammalian cortical development by differential expression of fringe genes. Brain Res Dev Brain Res. 2000 Feb 7;119(2):307-20 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:50796 Thelu J, Viallet JP, Dhouailly D, Differential expression pattern of the three Fringe genes is associated with epidermal differentiation. J Invest Dermatol. 1998 Nov;111(5):903-6 |
1 | J:112882 Xu Y, Wang S, Zhang J, Zhao A, Stanger BZ, Gu G, The fringe molecules induce endocrine differentiation in embryonic endoderm by activating cMyt1/cMyt3. Dev Biol. 2006 Sep 15;297(2):340-9 |
Mfsd6 major facilitator superfamily domain containing 6 (Synonyms: 2210010L05Rik, 9630025I22Rik, MMR2) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Mgat3 mannoside acetylglucosaminyltransferase 3 (Synonyms: 1110038J12Rik, GnT-III) | |
Results | Reference |
1* | J:76272 Bhattacharyya R, Bhaumik M, Raju TS, Stanley P, Truncated, Inactive N-Acetylglucosaminyltransferase III (GlcNAc-TIII) Induces Neurological and Other Traits Absent in Mice That Lack GlcNAc-TIII. J Biol Chem. 2002 Jul 19;277(29):26300-9 |
Mgat4c MGAT4 family, member C (Synonyms: 9130411I17Rik) | |
Results | Reference |
1 | J:326535 Petitpre C, Faure L, Uhl P, Fontanet P, Filova I, Pavlinkova G, Adameyko I, Hadjab S, Lallemend F, Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification. Nat Commun. 2022 Jul 5;13(1):3878 |
Mgll monoglyceride lipase (Synonyms: Magl) | |
Results | Reference |
3 | J:165476 Keimpema E, Barabas K, Morozov YM, Tortoriello G, Torii M, Cameron G, Yanagawa Y, Watanabe M, Mackie K, Harkany T, Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding. J Neurosci. 2010 Oct 20;30(42):13992-4007 |
1 | J:227268 Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Bjorklund P, Mackie K, Di Marzo V, Hokfelt TG, Dobrzyn A, Harkany T, Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6185-94 |
1 | J:171771 Wu CS, Zhu J, Wager-Miller J, Wang S, O'Leary D, Monory K, Lutz B, Mackie K, Lu HC, Requirement of cannabinoid CB(1) receptors in cortical pyramidal neurons for appropriate development of corticothalamic and thalamocortical projections. Eur J Neurosci. 2010 Sep;32(5):693-706 |
Mgp matrix Gla protein (Synonyms: Mglap) | |
Results | Reference |
1 | J:74145 Gori F, Schipani E, Demay MB, Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development. J Cell Biochem. 2001 Apr 2-27;82(1):46-57 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1* | J:23373 Luo G, D'Souza R, Hogue D, Karsenty G, The matrix Gla protein gene is a marker of the chondrogenesis cell lineage during mouse development. J Bone Miner Res. 1995 Feb;10(2):325-34 |
Mia MIA SH3 domain containing (Synonyms: Cdrap, Mia1) | |
Results | Reference |
1 | J:39335 Bosserhoff AK, Kondo S, Moser M, Dietz UH, Copeland NG, Gilbert DJ , Jenkins NA , Buettner R , Sandell LJ, Mouse CD-RAP/MIA gene: structure, chromosomal localization, and expression in cartilage and chondrosarcoma. Dev Dyn. 1997 Apr;208(4):516-25 |
1* | J:135990 Lin S, Ikegami M, Xu Y, Bosserhoff AK, Malkinson AM, Shannon JM, Misexpression of MIA disrupts lung morphogenesis and causes neonatal death. Dev Biol. 2008 Apr 15;316(2):441-55 |
Miat myocardial infarction associated transcript (non-protein coding) (Synonyms: A230057G18Rik, gomafu, Rncr2) | |
Results | Reference |
1* | J:283316 Garcia-Padilla C, Dominguez JN, Aranega AE, Franco D, Differential chamber-specific expression and regulation of long non-coding RNAs during cardiac development. Biochim Biophys Acta Gene Regul Mech. 2019 Oct;1862(10):194435 |
1* | J:161411 Rapicavoli NA, Poth EM, Blackshaw S, The long noncoding RNA RNCR2 directs mouse retinal cell specification. BMC Dev Biol. 2010;10:49 |
Mib1 MIB E3 ubiquitin protein ligase 1 (Synonyms: E430019M12Rik, Mib, mindbomb, mind bomb-1, skeletrophin) | |
Results | Reference |
1* | J:102528 Barsi JC, Rajendra R, Wu JI, Artzt K, Mind bomb1 is a ubiquitin ligase essential for mouse embryonic development and Notch signaling. Mech Dev. 2005 Oct;122(10):1106-17 |
1 | J:338889 Siguero-Alvarez M, Salguero-Jimenez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sanchez-Saez F, Pineiro-Sabaris R, Felipe-Medina N, Torroja C, Gomez MJ, Sabater-Molina M, Escriba R, Richaud-Patin I, Iglesias-Garcia O, Sbroggio M, Callejas S, O'Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibanez B, Monserrat L, Perez-Pomares JM, Sanchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL, A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation. 2023 Jan 3;147(1):47-65 |
Mib2 mindbomb E3 ubiquitin protein ligase 2 (Synonyms: 2210008I11Rik, Zzank1) | |
Results | Reference |
1* | J:129104 Wu JI, Rajendra R, Barsi JC, Durfee L, Benito E, Gao G, Kuruvilla M, Hrdlickova R, Liss AS, Artzt K, Targeted disruption of Mib2 causes exencephaly with a variable penetrance. Genesis. 2007 Nov;45(11):722-7 |
Micu1 mitochondrial calcium uptake 1 (Synonyms: C730016L05Rik, Cbara1) | |
Results | Reference |
1* | J:266097 Shanmughapriya S, Tomar D, Dong Z, Slovik KJ, Nemani N, Natarajaseenivasan K, Carvalho E, Lu C, Corrigan K, Garikipati VNS, Ibetti J, Rajan S, Barrero C, Chuprun K, Kishore R, Merali S, Tian Y, Yang W, Madesh M, FOXD1-dependent MICU1 expression regulates mitochondrial activity and cell differentiation. Nat Commun. 2018 Aug 29;9(1):3449 |
Mid1 midline 1 (Synonyms: 61B3-R, DXHXS1141, Fxy, Trim18) | |
Results | Reference |
1* | J:46361 Dal Zotto L, Quaderi NA, Elliott R, Lingerfelter PA, Carrel L , Valsecchi V , Montini E , Yen CH , Chapman V , Kalcheva I , Arrigo G , Zuffardi O , Thomas S , Willard HF , Ballabio A , Disteche CM , Rugarli EI, The mouse Mid1 gene: implications for the pathogenesis of Opitz syndrome and the evolution of the mammalian pseudoautosomal region. Hum Mol Genet. 1998 Mar;7(3):489-99 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Mid2 midline 2 (Synonyms: FXY2, Trim1) | |
Results | Reference |
1* | J:56619 Buchner G, Montini E, Andolfi G, Quaderi N, Cainarca S, Messali S, Bassi MT, Ballabio A, Meroni G, Franco B, MID2, a homologue of the Opitz syndrome gene MID1: similarities in subcellular localization and differences in expression during development. Hum Mol Genet. 1999 Aug;8(8):1397-407 |
Mif macrophage migration inhibitory factor (glycosylation-inhibiting factor) (Synonyms: Glif) | |
Results | Reference |
1 | J:225279 Arno B, Grassivaro F, Rossi C, Bergamaschi A, Castiglioni V, Furlan R, Greter M, Favaro R, Comi G, Becher B, Martino G, Muzio L, Neural progenitor cells orchestrate microglia migration and positioning into the developing cortex. Nat Commun. 2014;5:5611 |
1 | J:130907 Kevill KA, Bhandari V, Kettunen M, Leng L, Fan J, Mizue Y, Dzuira JD, Reyes-Mugica M, McDonald CL, Baugh JA, O'Connor CL, Aghai ZH, Donnelly SC, Bazzy-Asaad A, Bucala RJ, A role for macrophage migration inhibitory factor in the neonatal respiratory distress syndrome. J Immunol. 2008 Jan 1;180(1):601-8 |
1* | J:56414 Kobayashi S, Satomura K, Levsky JM, Sreenath T, Wistow GJ, Semba I, Shum L, Slavkin HC, Kulkarni AB, Expression pattern of macrophage migration inhibitory factor during embryogenesis. Mech Dev. 1999 Jun;84(1-2):153-6 |
Mink1 misshapen-like kinase 1 (zebrafish) (Synonyms: Map4k6, MINK, Misshapen/NIKs-related kinase, Ysk2) | |
Results | Reference |
1* | J:316481 Yu D, Hu J, Sheng Z, Fu G, Wang Y, Chen Y, Pan Z, Zhang X, Wu Y, Sun H, Dai J, Lu L, Ouyang H, Dual roles of misshapen/NIK-related kinase (MINK1) in osteoarthritis subtypes through the activation of TGFbeta signaling. Osteoarthritis Cartilage. 2020 Jan;28(1):112-121 |
Mip major intrinsic protein of lens fiber (Synonyms: Aqp0, aquaporin 0, Cts, lens opacity, Lop, MIP26, shrivelled, Svl) | |
Results | Reference |
1* | J:225905 Dash S, Dang CA, Beebe DC, Lachke SA, Deficiency of the RNA binding protein caprin2 causes lens defects and features of peters anomaly. Dev Dyn. 2015 Oct;244(10):1313-27 |
1* | J:95254 Grove M, Demyanenko G, Echarri A, Zipfel PA, Quiroz ME, Rodriguiz RM, Playford M, Martensen SA, Robinson MR, Wetsel WC, Maness PF, Pendergast AM, ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory. Mol Cell Biol. 2004 Dec;24(24):10905-22 |
2 | J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134 |
1 | J:207861 Manthey AL, Lachke SA, FitzGerald PG, Mason RW, Scheiblin DA, McDonald JH, Duncan MK, Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development. Mech Dev. 2014 Feb;131:86-110 |
1* | J:131929 Matteson PG, Desai J, Korstanje R, Lazar G, Borsuk TE, Rollins J, Kadambi S, Joseph J, Rahman T, Wink J, Benayed R, Paigen B, Millonig JH, The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2088-93 |
1* | J:23615 Morgenbesser SD, Schreiber-Agus N, Bidder M, Mahon KA, Overbeek PA, Horner J, DePinho RA, Contrasting roles for c-Myc and L-Myc in the regulation of cellular growth and differentiation in vivo. EMBO J. 1995 Feb 15;14(4):743-56 |
1 | J:284168 Nyeng P, Heilmann S, Lof-Ohlin ZM, Pettersson NF, Hermann FM, Reynolds AB, Semb H, p120ctn-Mediated Organ Patterning Precedes and Determines Pancreatic Progenitor Fate. Dev Cell. 2019 Apr 8;49(1):31-47.e9 |
1 | J:236785 Pathania M, Wang Y, Simirskii VN, Duncan MK, beta1-integrin controls cell fate specification in early lens development. Differentiation. 2016 Oct - Nov;92(4):133-147 |
1 | J:122566 Simirskii VN, Wang Y, Duncan MK, Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype. Dev Biol. 2007 Jun 15;306(2):658-68 |
1 | J:350084 Zhang L, Liu X, Li W, Liu K, Zhang J, Liu X, Wang J, Integrative transcriptomic profiling of ncRNAs and mRNAs in developing mouse lens. Front Genet. 2024;15:1405715 |
Mir1a-1 microRNA 1a-1 (Synonyms: Mirn1-1, Mirn1b, Mirn1c, Mirn1d, mmu-mir-1-1, mmu-mir-1a-1) | |
Results | Reference |
1 | J:131962 Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ, Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2111-6 |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1 | J:147774 Ikeda S, He A, Kong SW, Lu J, Bejar R, Bodyak N, Lee KH, Ma Q, Kang PM, Golub TR, Pu WT, MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol. 2009 Apr;29(8):2193-204 |
2 | J:291932 Nakamura T, Iwamoto T, Nakamura HM, Shindo Y, Saito K, Yamada A, Yamada Y, Fukumoto S, Nakamura T, Regulation of miR-1-Mediated Connexin 43 Expression and Cell Proliferation in Dental Epithelial Cells. Front Cell Dev Biol. 2020;8:156 |
Mir1a-2 microRNA 1a-2 (Synonyms: mir 1-2, Mirn1-2, mmu-mir-1-2, mmu-mir-1a-2) | |
Results | Reference |
1 | J:131962 Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ, Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2111-6 |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1 | J:147774 Ikeda S, He A, Kong SW, Lu J, Bejar R, Bodyak N, Lee KH, Ma Q, Kang PM, Golub TR, Pu WT, MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol. 2009 Apr;29(8):2193-204 |
2 | J:291932 Nakamura T, Iwamoto T, Nakamura HM, Shindo Y, Saito K, Yamada A, Yamada Y, Fukumoto S, Nakamura T, Regulation of miR-1-Mediated Connexin 43 Expression and Cell Proliferation in Dental Epithelial Cells. Front Cell Dev Biol. 2020;8:156 |
Mir7-1 microRNA 7-1 (Synonyms: mir 7-1, miR-7a1, Mir7a1, Mirn7-1, mmu-mir-7-1, mmu-mir-7a-1, mmu-miR-7a1) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1 | J:352077 Kane E, Mak TCS, Latreille M, MicroRNA-7 regulates endocrine progenitor delamination and endocrine cell mass in developing pancreatic islets. iScience. 2024 Jul 19;27(7):110332 |
1* | J:265657 Kleaveland B, Shi CY, Stefano J, Bartel DP, A Network of Noncoding Regulatory RNAs Acts in the Mammalian Brain. Cell. 2018 Jul 12;174(2):350-362.e17 |
1* | J:190429 Nieto M, Hevia P, Garcia E, Klein D, Alvarez-Cubela S, Bravo-Egana V, Rosero S, Damaris Molano R, Vargas N, Ricordi C, Pileggi A, Diez J, Dominguez-Bendala J, Pastori RL, Antisense miR-7 impairs insulin expression in developing pancreas and in cultured pancreatic buds. Cell Transplant. 2012;21(8):1761-74 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir7-2 microRNA 7-2 (Synonyms: mir 7-2, mir-7a2, Mir7a2, Mirn7-2, mmu-mir-7-2, mmu-mir-7a-2, mmu-mir-7a2) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1 | J:352077 Kane E, Mak TCS, Latreille M, MicroRNA-7 regulates endocrine progenitor delamination and endocrine cell mass in developing pancreatic islets. iScience. 2024 Jul 19;27(7):110332 |
1* | J:265657 Kleaveland B, Shi CY, Stefano J, Bartel DP, A Network of Noncoding Regulatory RNAs Acts in the Mammalian Brain. Cell. 2018 Jul 12;174(2):350-362.e17 |
1* | J:190429 Nieto M, Hevia P, Garcia E, Klein D, Alvarez-Cubela S, Bravo-Egana V, Rosero S, Damaris Molano R, Vargas N, Ricordi C, Pileggi A, Diez J, Dominguez-Bendala J, Pastori RL, Antisense miR-7 impairs insulin expression in developing pancreas and in cultured pancreatic buds. Cell Transplant. 2012;21(8):1761-74 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir7b microRNA 7b (Synonyms: mir 7b, Mirn7b, mmu-mir-7b) | |
Results | Reference |
1 | J:352077 Kane E, Mak TCS, Latreille M, MicroRNA-7 regulates endocrine progenitor delamination and endocrine cell mass in developing pancreatic islets. iScience. 2024 Jul 19;27(7):110332 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir9-1 microRNA 9-1 (Synonyms: Mirn9, Mirn9-1, mmu-mir-9-1) | |
Results | Reference |
1 | J:178118 Li Q, Bian S, Hong J, Kawase-Koga Y, Zhu E, Zheng Y, Yang L, Sun T, Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development. PLoS One. 2011;6(10):e26000 |
2* | J:244564 Lin Q, Ponnusamy R, Widagdo J, Choi JA, Ge W, Probst C, Buckley T, Lou M, Bredy TW, Fanselow MS, Ye K, Sun YE, MicroRNA-mediated disruption of dendritogenesis during a critical period of development influences cognitive capacity later in life. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9188-9193 |
2* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
1 | J:283783 Shu P, Wu C, Ruan X, Liu W, Hou L, Fu H, Wang M, Liu C, Zeng Y, Chen P, Yin B, Yuan J, Qiang B, Peng X, Zhong W, Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell. 2019 Jun 3;49(5):764-785.e4 |
1 | J:229563 Zhao J, Lin Q, Kim KJ, Dardashti FD, Kim J, He F, Sun Y, Ngn1 inhibits astrogliogenesis through induction of miR-9 during neuronal fate specification. Elife. 2015;4:e06885 |
Mir9-2 microRNA 9-2 (Synonyms: mir 9-2, Mirn9-2, mmu-mir-9-2) | |
Results | Reference |
1 | J:178118 Li Q, Bian S, Hong J, Kawase-Koga Y, Zhu E, Zheng Y, Yang L, Sun T, Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development. PLoS One. 2011;6(10):e26000 |
2* | J:244564 Lin Q, Ponnusamy R, Widagdo J, Choi JA, Ge W, Probst C, Buckley T, Lou M, Bredy TW, Fanselow MS, Ye K, Sun YE, MicroRNA-mediated disruption of dendritogenesis during a critical period of development influences cognitive capacity later in life. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9188-9193 |
1* | J:225478 Oliver PL, Chodroff RA, Gosal A, Edwards B, Cheung AF, Gomez-Rodriguez J, Elliot G, Garrett LJ, Lickiss T, Szele F, Green ED, Molnar Z, Ponting CP, Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype. Cereb Cortex. 2015 Oct;25(10):3572-85 |
2* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
1 | J:283783 Shu P, Wu C, Ruan X, Liu W, Hou L, Fu H, Wang M, Liu C, Zeng Y, Chen P, Yin B, Yuan J, Qiang B, Peng X, Zhong W, Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell. 2019 Jun 3;49(5):764-785.e4 |
1 | J:229563 Zhao J, Lin Q, Kim KJ, Dardashti FD, Kim J, He F, Sun Y, Ngn1 inhibits astrogliogenesis through induction of miR-9 during neuronal fate specification. Elife. 2015;4:e06885 |
Mir9-2hg Mir9-2 host gene (Synonyms: 2810449C10Rik, C130071C03Rik, C130071C03Riken, NDIME) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
2* | J:225478 Oliver PL, Chodroff RA, Gosal A, Edwards B, Cheung AF, Gomez-Rodriguez J, Elliot G, Garrett LJ, Lickiss T, Szele F, Green ED, Molnar Z, Ponting CP, Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype. Cereb Cortex. 2015 Oct;25(10):3572-85 |
1* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Mir9-3 microRNA 9-3 (Synonyms: mir 9-3, Mirn9-3, mmu-mir-9-3) | |
Results | Reference |
1 | J:178118 Li Q, Bian S, Hong J, Kawase-Koga Y, Zhu E, Zheng Y, Yang L, Sun T, Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development. PLoS One. 2011;6(10):e26000 |
2* | J:244564 Lin Q, Ponnusamy R, Widagdo J, Choi JA, Ge W, Probst C, Buckley T, Lou M, Bredy TW, Fanselow MS, Ye K, Sun YE, MicroRNA-mediated disruption of dendritogenesis during a critical period of development influences cognitive capacity later in life. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9188-9193 |
2* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
1 | J:283783 Shu P, Wu C, Ruan X, Liu W, Hou L, Fu H, Wang M, Liu C, Zeng Y, Chen P, Yin B, Yuan J, Qiang B, Peng X, Zhong W, Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell. 2019 Jun 3;49(5):764-785.e4 |
1 | J:229563 Zhao J, Lin Q, Kim KJ, Dardashti FD, Kim J, He F, Sun Y, Ngn1 inhibits astrogliogenesis through induction of miR-9 during neuronal fate specification. Elife. 2015;4:e06885 |
Mir10a microRNA 10a (Synonyms: MicroRNA-10a, mir 10a, miR-10a, Mirn10a, mmu-mir-10a) | |
Results | Reference |
1 | J:321428 Kruber P, Angay O, Winkler A, Bosl MR, Kneitz S, Heinze KG, Gessler M, Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation. Int J Cancer. 2019 Mar 15;144(6):1391-1400 |
Mir10b microRNA 10b (Synonyms: mir-10b, Mirn10b, mmu-mir-10b) | |
Results | Reference |
1 | J:321428 Kruber P, Angay O, Winkler A, Bosl MR, Kneitz S, Heinze KG, Gessler M, Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation. Int J Cancer. 2019 Mar 15;144(6):1391-1400 |
Mir15a microRNA 15a (Synonyms: Mirn15a, mmu-mir-15a) | |
Results | Reference |
1 | J:148395 Friedman LM, Dror AA, Mor E, Tenne T, Toren G, Satoh T, Biesemeier DJ, Shomron N, Fekete DM, Hornstein E, Avraham KB, MicroRNAs are essential for development and function of inner ear hair cells in vertebrates. Proc Natl Acad Sci U S A. 2009 May 12;106(19):7915-20 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir15b microRNA 15b (Synonyms: Mirn15b, mmu-mir-15b) | |
Results | Reference |
1* | J:313935 Fishman ES, Louie M, Miltner AM, Cheema SK, Wong J, Schlaeger NM, Moshiri A, Simo S, Tarantal AF, La Torre A, MicroRNA Signatures of the Developing Primate Fovea. Front Cell Dev Biol. 2021;9:654385 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir16-1 microRNA 16-1 (Synonyms: miR-16, mir-16-1, Mirn16, Mirn16-1, mmu-mir-16-1) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1 | J:223034 Krol J, Krol I, Alvarez CP, Fiscella M, Hierlemann A, Roska B, Filipowicz W, A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture. Nat Commun. 2015;6:7305 |
Mir16-2 microRNA 16-2 (Synonyms: mir-16-2, Mirn16-2, mmu-mir-16-2) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1 | J:223034 Krol J, Krol I, Alvarez CP, Fiscella M, Hierlemann A, Roska B, Filipowicz W, A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture. Nat Commun. 2015;6:7305 |
Mir17 microRNA 17 (Synonyms: mir 17, Mirn17, mmu-mir-17) | |
Results | Reference |
1 | J:339612 Altounian M, Bellon A, Mann F, Neuronal miR-17-5p contributes to interhemispheric cortical connectivity defects induced by prenatal alcohol exposure. Cell Rep. 2023 Aug 22;42(9):113020 |
1* | J:152495 Carraro G, El-Hashash A, Guidolin D, Tiozzo C, Turcatel G, Young BM, De Langhe SP, Bellusci S, Shi W, Parnigotto PP, Warburton D, miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution. Dev Biol. 2009 Sep 15;333(2):238-50 |
Mir18 microRNA 18 (Synonyms: Mirn18, mmu-mir-18, mmu-mir-18a) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1 | J:148395 Friedman LM, Dror AA, Mor E, Tenne T, Toren G, Satoh T, Biesemeier DJ, Shomron N, Fekete DM, Hornstein E, Avraham KB, MicroRNAs are essential for development and function of inner ear hair cells in vertebrates. Proc Natl Acad Sci U S A. 2009 May 12;106(19):7915-20 |
Mir19a microRNA 19a (Synonyms: mir 19a, Mirn19a, mmu-mir-19a) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1* | J:279731 Liu K, Hao Q, Wei J, Li GH, Wu Y, Zhao YF, MicroRNA-19a/b-3p protect the heart from hypertension-induced pathological cardiac hypertrophy through PDE5A. J Hypertens. 2018 Sep;36(9):1847-1857 |
1 | J:214730 Zindy F, Kawauchi D, Lee Y, Ayrault O, Ben Merzoug L, McKinnon PJ, Ventura A, Roussel MF, Role of the miR-17 approximately 92 cluster family in cerebellar and medulloblastoma development. Biol Open. 2014;3(7):597-605 |
1 | J:237792 Zindy F, Lee Y, Kawauchi D, Ayrault O, Merzoug LB, Li Y, McKinnon PJ, Roussel MF, Dicer Is Required for Normal Cerebellar Development and to Restrain Medulloblastoma Formation. PLoS One. 2015;10(6):e0129642 |
Mir19b-1 microRNA 19b-1 (Synonyms: mir 19b-1, Mirn19b-1, mmu-mir-19b-1) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1* | J:279731 Liu K, Hao Q, Wei J, Li GH, Wu Y, Zhao YF, MicroRNA-19a/b-3p protect the heart from hypertension-induced pathological cardiac hypertrophy through PDE5A. J Hypertens. 2018 Sep;36(9):1847-1857 |
1 | J:214730 Zindy F, Kawauchi D, Lee Y, Ayrault O, Ben Merzoug L, McKinnon PJ, Ventura A, Roussel MF, Role of the miR-17 approximately 92 cluster family in cerebellar and medulloblastoma development. Biol Open. 2014;3(7):597-605 |
Mir19b-2 microRNA 19b-2 (Synonyms: Mirn19b, Mirn19b-2, mmu-mir-19b-2) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1* | J:279731 Liu K, Hao Q, Wei J, Li GH, Wu Y, Zhao YF, MicroRNA-19a/b-3p protect the heart from hypertension-induced pathological cardiac hypertrophy through PDE5A. J Hypertens. 2018 Sep;36(9):1847-1857 |
1 | J:214730 Zindy F, Kawauchi D, Lee Y, Ayrault O, Ben Merzoug L, McKinnon PJ, Ventura A, Roussel MF, Role of the miR-17 approximately 92 cluster family in cerebellar and medulloblastoma development. Biol Open. 2014;3(7):597-605 |
Mir20a microRNA 20a (Synonyms: Mir-20, Mirn20, Mirn20a, mmu-mir-20a) | |
Results | Reference |
1* | J:152495 Carraro G, El-Hashash A, Guidolin D, Tiozzo C, Turcatel G, Young BM, De Langhe SP, Bellusci S, Shi W, Parnigotto PP, Warburton D, miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution. Dev Biol. 2009 Sep 15;333(2):238-50 |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
Mir21a microRNA 21a (Synonyms: Mirn21, mmu-mir-21, mmu-mir-21a) | |
Results | Reference |
1 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1 | J:197235 Bhandari A, Gordon W, Dizon D, Hopkin AS, Gordon E, Yu Z, Andersen B, The Grainyhead transcription factor Grhl3/Get1 suppresses miR-21 expression and tumorigenesis in skin: modulation of the miR-21 target MSH2 by RNA-binding protein DND1. Oncogene. 2013 Mar 21;32(12):1497-507 |
Mir22 microRNA 22 (Synonyms: Mirn22, mmu-mir-22) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
Mir23a microRNA 23a (Synonyms: Mirn23a, mmu-mir-23a) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1 | J:327958 Eliason S, Su D, Pinho F, Sun Z, Zhang Z, Li X, Sweat M, Venugopalan SR, He B, Bustin M, Amendt BA, HMGN2 represses gene transcription via interaction with transcription factors Lef-1 and Pitx2 during amelogenesis. J Biol Chem. 2022 Jul 21;298(9):102295 |
1 | J:342842 Su D, Eliason S, Sun Z, Shao F, Amendt BA, Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development. J Biol Chem. 2023 Nov;299(11):105324 |
1* | J:187172 Wang L, Chen X, Zheng Y, Li F, Lu Z, Chen C, Liu J, Wang Y, Peng Y, Shen Z, Gao J, Zhu M, Chen H, MiR-23a inhibits myogenic differentiation through down regulation of fast myosin heavy chain isoforms. Exp Cell Res. 2012 Nov 1;318(18):2324-34 |
Mir23b microRNA 23b (Synonyms: Mirn23b, mmu-mir-23b) | |
Results | Reference |
1 | J:327958 Eliason S, Su D, Pinho F, Sun Z, Zhang Z, Li X, Sweat M, Venugopalan SR, He B, Bustin M, Amendt BA, HMGN2 represses gene transcription via interaction with transcription factors Lef-1 and Pitx2 during amelogenesis. J Biol Chem. 2022 Jul 21;298(9):102295 |
1 | J:342842 Su D, Eliason S, Sun Z, Shao F, Amendt BA, Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development. J Biol Chem. 2023 Nov;299(11):105324 |
Mir24-1 microRNA 24-1 (Synonyms: miR-24-1, Mirn189, Mirn24, Mirn24-1, mmu-mir-24-1) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1 | J:188151 Repetto E, Briata P, Kuziner N, Harfe BD, McManus MT, Gherzi R, Rosenfeld MG, Trabucchi M, Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP. PLoS Genet. 2012 Jul;8(7):e1002823 |
1 | J:342842 Su D, Eliason S, Sun Z, Shao F, Amendt BA, Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development. J Biol Chem. 2023 Nov;299(11):105324 |
Mir24-2 microRNA 24-2 (Synonyms: mir 24-2, Mirn24-2, mmu-mir-24-2) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1 | J:188151 Repetto E, Briata P, Kuziner N, Harfe BD, McManus MT, Gherzi R, Rosenfeld MG, Trabucchi M, Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP. PLoS Genet. 2012 Jul;8(7):e1002823 |
1 | J:342842 Su D, Eliason S, Sun Z, Shao F, Amendt BA, Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development. J Biol Chem. 2023 Nov;299(11):105324 |
Mir26a-1 microRNA 26a-1 (Synonyms: Mirn26a, Mirn26a-1, mmu-mir-26a-1) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
Mir26a-2 microRNA 26a-2 (Synonyms: mir 26a-2, Mirn26a-2, mmu-mir-26a-2) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
Mir27b microRNA 27b (Synonyms: Mirn27b, mmu-mir-27b) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1 | J:188151 Repetto E, Briata P, Kuziner N, Harfe BD, McManus MT, Gherzi R, Rosenfeld MG, Trabucchi M, Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP. PLoS Genet. 2012 Jul;8(7):e1002823 |
Mir29a microRNA 29a (Synonyms: Mirn29a, mmu-mir-29a) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
Mir29b-1 microRNA 29b-1 (Synonyms: Mirn29b, Mirn29b-1, mmu-mir-29b-1) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir29b-2 microRNA 29b-2 (Synonyms: mir 29b-2, Mirn29b-2, mmu-mir-29b-2) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir30a microRNA 30a (Synonyms: Mirn30a, mmu-mir-30a) | |
Results | Reference |
2* | J:146851 Hand NJ, Master ZR, Eauclaire SF, Weinblatt DE, Matthews RP, Friedman JR, The microRNA-30 family is required for vertebrate hepatobiliary development. Gastroenterology. 2009 Mar;136(3):1081-90 |
1 | J:147774 Ikeda S, He A, Kong SW, Lu J, Bejar R, Bodyak N, Lee KH, Ma Q, Kang PM, Golub TR, Pu WT, MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol. 2009 Apr;29(8):2193-204 |
Mir30b microRNA 30b (Synonyms: Mirn30b, mmu-mir-30b) | |
Results | Reference |
1* | J:313935 Fishman ES, Louie M, Miltner AM, Cheema SK, Wong J, Schlaeger NM, Moshiri A, Simo S, Tarantal AF, La Torre A, MicroRNA Signatures of the Developing Primate Fovea. Front Cell Dev Biol. 2021;9:654385 |
1 | J:148395 Friedman LM, Dror AA, Mor E, Tenne T, Toren G, Satoh T, Biesemeier DJ, Shomron N, Fekete DM, Hornstein E, Avraham KB, MicroRNAs are essential for development and function of inner ear hair cells in vertebrates. Proc Natl Acad Sci U S A. 2009 May 12;106(19):7915-20 |
1* | J:146851 Hand NJ, Master ZR, Eauclaire SF, Weinblatt DE, Matthews RP, Friedman JR, The microRNA-30 family is required for vertebrate hepatobiliary development. Gastroenterology. 2009 Mar;136(3):1081-90 |
1 | J:147774 Ikeda S, He A, Kong SW, Lu J, Bejar R, Bodyak N, Lee KH, Ma Q, Kang PM, Golub TR, Pu WT, MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol. 2009 Apr;29(8):2193-204 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir30c-1 microRNA 30c-1 (Synonyms: Mirn30c, Mirn30c-1, mmu-mir-30c-1) | |
Results | Reference |
2* | J:146851 Hand NJ, Master ZR, Eauclaire SF, Weinblatt DE, Matthews RP, Friedman JR, The microRNA-30 family is required for vertebrate hepatobiliary development. Gastroenterology. 2009 Mar;136(3):1081-90 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir30c-2 microRNA 30c-2 (Synonyms: mir 30c-2, Mirn30c-2, mmu-mir-30c-2) | |
Results | Reference |
2* | J:146851 Hand NJ, Master ZR, Eauclaire SF, Weinblatt DE, Matthews RP, Friedman JR, The microRNA-30 family is required for vertebrate hepatobiliary development. Gastroenterology. 2009 Mar;136(3):1081-90 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir30d microRNA 30d (Synonyms: Mirn30d, mmu-mir-30d) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1* | J:146851 Hand NJ, Master ZR, Eauclaire SF, Weinblatt DE, Matthews RP, Friedman JR, The microRNA-30 family is required for vertebrate hepatobiliary development. Gastroenterology. 2009 Mar;136(3):1081-90 |
Mir30e microRNA 30e (Synonyms: mir 30e, Mirn30e, mmu-mir-30e) | |
Results | Reference |
1* | J:146851 Hand NJ, Master ZR, Eauclaire SF, Weinblatt DE, Matthews RP, Friedman JR, The microRNA-30 family is required for vertebrate hepatobiliary development. Gastroenterology. 2009 Mar;136(3):1081-90 |
Mir31 microRNA 31 (Synonyms: mir 31, miR-31, Mirn31, mmu-mir-31) | |
Results | Reference |
1* | J:160269 Michon F, Tummers M, Kyyronen M, Frilander MJ, Thesleff I, Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol. 2010 Apr 15;340(2):355-68 |
Mir34a microRNA 34a (Synonyms: mir 34a, Mirn34a, mmu-mir-34a) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
Mir34b microRNA 34b (Synonyms: mir 34b, Mirn34b, mmu-mir-34b) | |
Results | Reference |
1 | J:185130 Wei J, Shi Y, Zheng L, Zhou B, Inose H, Wang J, Guo XE, Grosschedl R, Karsenty G, miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. J Cell Biol. 2012 May 14;197(4):509-21 |
Mir92-1 microRNA 92-1 (Synonyms: mir 92-1, Mirn92-1, mmu-mir-92-1, mmu-mir-92a-1) | |
Results | Reference |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir92-2 microRNA 92-2 (Synonyms: mir 92-2, Mirn92-2, mmu-mir-92-2, mmu-mir-92a-2) | |
Results | Reference |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir92b microRNA 92b (Synonyms: Mirn92b, mmu-mir-92b) | |
Results | Reference |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir93 microRNA 93 (Synonyms: mir 93, Mirn93, mmu-mir-93) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1* | J:313935 Fishman ES, Louie M, Miltner AM, Cheema SK, Wong J, Schlaeger NM, Moshiri A, Simo S, Tarantal AF, La Torre A, MicroRNA Signatures of the Developing Primate Fovea. Front Cell Dev Biol. 2021;9:654385 |
Mir96 microRNA 96 (Synonyms: mir 96, Mirn96, mmu-mir-96) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1 | J:223034 Krol J, Krol I, Alvarez CP, Fiscella M, Hierlemann A, Roska B, Filipowicz W, A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture. Nat Commun. 2015;6:7305 |
Mir99a microRNA 99a (Synonyms: Mirn99a, mmu-mir-99a) | |
Results | Reference |
1 | J:148395 Friedman LM, Dror AA, Mor E, Tenne T, Toren G, Satoh T, Biesemeier DJ, Shomron N, Fekete DM, Hornstein E, Avraham KB, MicroRNAs are essential for development and function of inner ear hair cells in vertebrates. Proc Natl Acad Sci U S A. 2009 May 12;106(19):7915-20 |
Mir100hg Mir100 Mirlet7a-2 Mir125b-1 cluster host gene (Synonyms: 2610203C20Rik, 3110039I08Rik, D230004N17Rik) | |
Results | Reference |
1 | J:331893 Yang J, Zhang L, Li Y, Chen M, Identifying key m(6)A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses. Front Genet. 2022;13:974357 |
Mir103-1 microRNA 103-1 (Synonyms: mir 103-1, Mirn103-1, mmu-mir-103-1) | |
Results | Reference |
1* | J:313935 Fishman ES, Louie M, Miltner AM, Cheema SK, Wong J, Schlaeger NM, Moshiri A, Simo S, Tarantal AF, La Torre A, MicroRNA Signatures of the Developing Primate Fovea. Front Cell Dev Biol. 2021;9:654385 |
Mir103-2 microRNA 103-2 (Synonyms: mir 103-2, mir-103-2, Mirn103-2, mmu-mir-103-2) | |
Results | Reference |
1* | J:313935 Fishman ES, Louie M, Miltner AM, Cheema SK, Wong J, Schlaeger NM, Moshiri A, Simo S, Tarantal AF, La Torre A, MicroRNA Signatures of the Developing Primate Fovea. Front Cell Dev Biol. 2021;9:654385 |
Mir106a microRNA 106a (Synonyms: mir 106a, Mirn106a, mmu-mir-106a) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
1 | J:283373 Zhang W, Shen Z, Xing Y, Zhao H, Liang Y, Chen J, Zhong X, Shi L, Wan X, Zhou J, Tang S, MiR-106a-5p modulates apoptosis and metabonomics changes by TGF-beta/Smad signaling pathway in cleft palate. Exp Cell Res. 2020 Jan 15;386(2):111734 |
Mir106b microRNA 106b (Synonyms: mir 106b, Mirn106b, mmu-mir-106b) | |
Results | Reference |
1* | J:152495 Carraro G, El-Hashash A, Guidolin D, Tiozzo C, Turcatel G, Young BM, De Langhe SP, Bellusci S, Shi W, Parnigotto PP, Warburton D, miR-17 family of microRNAs controls FGF10-mediated embryonic lung epithelial branching morphogenesis through MAPK14 and STAT3 regulation of E-Cadherin distribution. Dev Biol. 2009 Sep 15;333(2):238-50 |
1 | J:237792 Zindy F, Lee Y, Kawauchi D, Ayrault O, Merzoug LB, Li Y, McKinnon PJ, Roussel MF, Dicer Is Required for Normal Cerebellar Development and to Restrain Medulloblastoma Formation. PLoS One. 2015;10(6):e0129642 |
Mir107 microRNA 107 (Synonyms: mir 107, Mirn107, mmu-mir-107) | |
Results | Reference |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
Mir122 microRNA 122 (Synonyms: Mir122a, Mir122b, Mirn122a, Mirn122b, mmu-mir-122, mmu-mir-122a) | |
Results | Reference |
1 | J:117766 Chang J, Nicolas E, Marks D, Sander C, Lerro A, Buendia MA, Xu C, Mason WS, Moloshok T, Bort R, Zaret KS, Taylor JM, miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1. RNA Biol. 2004 Jul;1(2):106-13 |
1* | J:146851 Hand NJ, Master ZR, Eauclaire SF, Weinblatt DE, Matthews RP, Friedman JR, The microRNA-30 family is required for vertebrate hepatobiliary development. Gastroenterology. 2009 Mar;136(3):1081-90 |
Mir124-2hg Mir124-2 host gene (non-protein coding) (Synonyms: 2610100L16Rik, 6430547I21Rik, A930005K07Rik, Gm2612) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Mir124a-1 microRNA 124a-1 (Synonyms: Mirn124a, Mirn124a-1, mmu-mir-124-1, mmu-mir-124a-1) | |
Results | Reference |
1 | J:111626 Deo M, Yu JY, Chung KH, Tippens M, Turner DL, Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides. Dev Dyn. 2006 May 30;235(9):2538-2548 |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1 | J:229060 Franzoni E, Booker SA, Parthasarathy S, Rehfeld F, Grosser S, Srivatsa S, Fuchs HR, Tarabykin V, Vida I, Wulczyn FG, miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6. Elife. 2015;4 |
1 | J:315409 Huyghe A, Van den Ackerveken P, Sacheli R, Prevot PP, Thelen N, Renauld J, Thiry M, Delacroix L, Nguyen L, Malgrange B, MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5. Cell Rep. 2015 Oct 6;13(1):31-42 |
1* | J:159510 Maiorano NA, Mallamaci A, Promotion of embryonic cortico-cerebral neuronogenesis by miR-124. Neural Dev. 2009;4:40 |
1 | J:320700 Shtukmaster S, Narasimhan P, El Faitwri T, Stubbusch J, Ernsberger U, Rohrer H, Unsicker K, Huber K, MiR-124 is differentially expressed in derivatives of the sympathoadrenal cell lineage and promotes neurite elongation in chromaffin cells. Cell Tissue Res. 2016 Aug;365(2):225-32 |
1 | J:283783 Shu P, Wu C, Ruan X, Liu W, Hou L, Fu H, Wang M, Liu C, Zeng Y, Chen P, Yin B, Yuan J, Qiang B, Peng X, Zhong W, Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell. 2019 Jun 3;49(5):764-785.e4 |
Mir124a-2 microRNA 124a-2 (Synonyms: mir-124a-2, Mirn124a-2, mmu-mir-124-2, mmu-mir-124a-2) | |
Results | Reference |
1 | J:111626 Deo M, Yu JY, Chung KH, Tippens M, Turner DL, Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides. Dev Dyn. 2006 May 30;235(9):2538-2548 |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1 | J:229060 Franzoni E, Booker SA, Parthasarathy S, Rehfeld F, Grosser S, Srivatsa S, Fuchs HR, Tarabykin V, Vida I, Wulczyn FG, miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6. Elife. 2015;4 |
1* | J:159510 Maiorano NA, Mallamaci A, Promotion of embryonic cortico-cerebral neuronogenesis by miR-124. Neural Dev. 2009;4:40 |
1 | J:320700 Shtukmaster S, Narasimhan P, El Faitwri T, Stubbusch J, Ernsberger U, Rohrer H, Unsicker K, Huber K, MiR-124 is differentially expressed in derivatives of the sympathoadrenal cell lineage and promotes neurite elongation in chromaffin cells. Cell Tissue Res. 2016 Aug;365(2):225-32 |
1 | J:283783 Shu P, Wu C, Ruan X, Liu W, Hou L, Fu H, Wang M, Liu C, Zeng Y, Chen P, Yin B, Yuan J, Qiang B, Peng X, Zhong W, Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell. 2019 Jun 3;49(5):764-785.e4 |
Mir124a-3 microRNA 124a-3 (Synonyms: mir-124a-3, Mirn124a-3, mmu-mir-124-3, mmu-mir-124a-3) | |
Results | Reference |
1 | J:111626 Deo M, Yu JY, Chung KH, Tippens M, Turner DL, Detection of mammalian microRNA expression by in situ hybridization with RNA oligonucleotides. Dev Dyn. 2006 May 30;235(9):2538-2548 |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1 | J:229060 Franzoni E, Booker SA, Parthasarathy S, Rehfeld F, Grosser S, Srivatsa S, Fuchs HR, Tarabykin V, Vida I, Wulczyn FG, miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6. Elife. 2015;4 |
1* | J:159510 Maiorano NA, Mallamaci A, Promotion of embryonic cortico-cerebral neuronogenesis by miR-124. Neural Dev. 2009;4:40 |
1 | J:320700 Shtukmaster S, Narasimhan P, El Faitwri T, Stubbusch J, Ernsberger U, Rohrer H, Unsicker K, Huber K, MiR-124 is differentially expressed in derivatives of the sympathoadrenal cell lineage and promotes neurite elongation in chromaffin cells. Cell Tissue Res. 2016 Aug;365(2):225-32 |
1 | J:283783 Shu P, Wu C, Ruan X, Liu W, Hou L, Fu H, Wang M, Liu C, Zeng Y, Chen P, Yin B, Yuan J, Qiang B, Peng X, Zhong W, Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell. 2019 Jun 3;49(5):764-785.e4 |
Mir125a microRNA 125a (Synonyms: Mirn125a, mmu-mir-125a) | |
Results | Reference |
1* | J:102849 Schulman BR, Esquela-Kerscher A, Slack FJ, Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis. Dev Dyn. 2005 Dec;234(4):1046-54 |
Mir125b-1 microRNA 125b-1 (Synonyms: Mirn125b, Mirn125b-1, mmu-mir-125b-1) | |
Results | Reference |
1* | J:102849 Schulman BR, Esquela-Kerscher A, Slack FJ, Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis. Dev Dyn. 2005 Dec;234(4):1046-54 |
Mir125b-2 microRNA 125b-2 (Synonyms: mir-125b-2, Mirn125b-2, mmu-mir-125b-2) | |
Results | Reference |
1* | J:102849 Schulman BR, Esquela-Kerscher A, Slack FJ, Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis. Dev Dyn. 2005 Dec;234(4):1046-54 |
Mir126a microRNA 126a (Synonyms: Mirn126, mmu-mir-126, mmu-mir-126a) | |
Results | Reference |
1 | J:321428 Kruber P, Angay O, Winkler A, Bosl MR, Kneitz S, Heinze KG, Gessler M, Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation. Int J Cancer. 2019 Mar 15;144(6):1391-1400 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
Mir127 microRNA 127 (Synonyms: Mirn127, mmu-mir-127) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1* | J:146851 Hand NJ, Master ZR, Eauclaire SF, Weinblatt DE, Matthews RP, Friedman JR, The microRNA-30 family is required for vertebrate hepatobiliary development. Gastroenterology. 2009 Mar;136(3):1081-90 |
1* | J:224145 Ito M, Sferruzzi-Perri AN, Edwards CA, Adalsteinsson BT, Allen SE, Loo TH, Kitazawa M, Kaneko-Ishino T, Ishino F, Stewart CL, Ferguson-Smith AC, A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development. Development. 2015 Jul 15;142(14):2425-30 |
1* | J:166176 Zhou Y, Cheunsuchon P, Nakayama Y, Lawlor MW, Zhong Y, Rice KA, Zhang L, Zhang X, Gordon FE, Lidov HG, Bronson RT, Klibanski A, Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. Development. 2010 Aug;137(16):2643-52 |
Mir128-1 microRNA 128-1 (Synonyms: Mirn128, Mirn128-1, Mirn128a, mmu-mir-128-1, mmu-mir-128a) | |
Results | Reference |
2 | J:229060 Franzoni E, Booker SA, Parthasarathy S, Rehfeld F, Grosser S, Srivatsa S, Fuchs HR, Tarabykin V, Vida I, Wulczyn FG, miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6. Elife. 2015;4 |
1 | J:223034 Krol J, Krol I, Alvarez CP, Fiscella M, Hierlemann A, Roska B, Filipowicz W, A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture. Nat Commun. 2015;6:7305 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
1 | J:283783 Shu P, Wu C, Ruan X, Liu W, Hou L, Fu H, Wang M, Liu C, Zeng Y, Chen P, Yin B, Yuan J, Qiang B, Peng X, Zhong W, Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell. 2019 Jun 3;49(5):764-785.e4 |
Mir128-2 microRNA 128-2 (Synonyms: mir 128b, mir-128b, Mirn128-2, Mirn128b, mmu-mir-128-2, mmu-mir-128b) | |
Results | Reference |
2 | J:229060 Franzoni E, Booker SA, Parthasarathy S, Rehfeld F, Grosser S, Srivatsa S, Fuchs HR, Tarabykin V, Vida I, Wulczyn FG, miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6. Elife. 2015;4 |
1 | J:223034 Krol J, Krol I, Alvarez CP, Fiscella M, Hierlemann A, Roska B, Filipowicz W, A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture. Nat Commun. 2015;6:7305 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
1 | J:283783 Shu P, Wu C, Ruan X, Liu W, Hou L, Fu H, Wang M, Liu C, Zeng Y, Chen P, Yin B, Yuan J, Qiang B, Peng X, Zhong W, Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell. 2019 Jun 3;49(5):764-785.e4 |
Mir129-1 microRNA 129-1 (Synonyms: Mirn129-1, Mirn129b, mmu-mir-129-1) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir129-2 microRNA 129-2 (Synonyms: Mirn129-2, mmu-mir-129-2) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir130a microRNA 130a (Synonyms: Mirn130, Mirn130a, mmu-mir-130a) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
2* | J:199420 Mujahid S, Nielsen HC, Volpe MV, MiR-221 and miR-130a regulate lung airway and vascular development. PLoS One. 2013;8(2):e55911 |
Mir130b microRNA 130b (Synonyms: mir 130b, Mirn130b, mmu-mir-130b) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
Mir132 microRNA 132 (Synonyms: Mirn132, mmu-mir-132) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1 | J:205590 Hancock ML, Preitner N, Quan J, Flanagan JG, MicroRNA-132 is enriched in developing axons, locally regulates Rasa1 mRNA, and promotes axon extension. J Neurosci. 2014 Jan 1;34(1):66-78 |
Mir133a-1 microRNA 133a-1 (Synonyms: mir-133a-1, Mirn133, Mirn133a-1, mmu-mir-133a-1) | |
Results | Reference |
1 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1 | J:131962 Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ, Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2111-6 |
1 | J:147774 Ikeda S, He A, Kong SW, Lu J, Bejar R, Bodyak N, Lee KH, Ma Q, Kang PM, Golub TR, Pu WT, MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol. 2009 Apr;29(8):2193-204 |
Mir133a-2 microRNA 133a-2 (Synonyms: mir 133a-2, Mirn133a-2, mmu-mir-133a-2) | |
Results | Reference |
1 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1 | J:131962 Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ, Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2111-6 |
1 | J:147774 Ikeda S, He A, Kong SW, Lu J, Bejar R, Bodyak N, Lee KH, Ma Q, Kang PM, Golub TR, Pu WT, MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol. 2009 Apr;29(8):2193-204 |
Mir133b microRNA 133b (Synonyms: mir 133b, Mirn133b, mmu-mir-133b) | |
Results | Reference |
1 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1 | J:131962 Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ, Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2111-6 |
1 | J:147774 Ikeda S, He A, Kong SW, Lu J, Bejar R, Bodyak N, Lee KH, Ma Q, Kang PM, Golub TR, Pu WT, MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol. 2009 Apr;29(8):2193-204 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir134 microRNA 134 (Synonyms: Mirn134, mmu-mir-134) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir135a-1 microRNA 135a-1 (Synonyms: Mirn135, Mirn135a-1, mmu-mir-135a-1) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir135a-2 microRNA 135a-2 (Synonyms: mir 135a-2, Mirn135a-2, mmu-mir-135a-2) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir135b microRNA 135b (Synonyms: mir 135b, Mirn135b, mmu-mir-135b) | |
Results | Reference |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir136 microRNA 136 (Synonyms: Mirn136, mmu-mir-136) | |
Results | Reference |
1* | J:224145 Ito M, Sferruzzi-Perri AN, Edwards CA, Adalsteinsson BT, Allen SE, Loo TH, Kitazawa M, Kaneko-Ishino T, Ishino F, Stewart CL, Ferguson-Smith AC, A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development. Development. 2015 Jul 15;142(14):2425-30 |
Mir137 microRNA 137 (Synonyms: Mirn137, mmu-mir-137) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir138-1 microRNA 138-1 (Synonyms: Mirn138, Mirn138-1, mmu-mir-138-1) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1 | J:201069 Stubbusch J, Narasimhan P, Huber K, Unsicker K, Rohrer H, Ernsberger U, Synaptic protein and pan-neuronal gene expression and their regulation by Dicer-dependent mechanisms differ between neurons and neuroendocrine cells. Neural Dev. 2013 Aug 20;8(1):16 |
Mir138-2 microRNA 138-2 (Synonyms: mir 138-2, Mirn138-2, mmu-mir-138-2) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1 | J:201069 Stubbusch J, Narasimhan P, Huber K, Unsicker K, Rohrer H, Ernsberger U, Synaptic protein and pan-neuronal gene expression and their regulation by Dicer-dependent mechanisms differ between neurons and neuroendocrine cells. Neural Dev. 2013 Aug 20;8(1):16 |
Mir140 microRNA 140 (Synonyms: Mirn140, mmu-mir-140) | |
Results | Reference |
1* | J:160269 Michon F, Tummers M, Kyyronen M, Frilander MJ, Thesleff I, Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol. 2010 Apr 15;340(2):355-68 |
1* | J:163875 Wang XR, Zhang XM, Zhen J, Zhang PX, Xu G, Jiang H, MicroRNA expression in the embryonic mouse inner ear. Neuroreport. 2010 Jun 23;21(9):611-7 |
1 | J:187536 Yamashita S, Miyaki S, Kato Y, Yokoyama S, Sato T, Barrionuevo F, Akiyama H, Scherer G, Takada S, Asahara H, L-Sox5 and Sox6 proteins enhance chondrogenic miR-140 microRNA expression by strengthening dimeric Sox9 activity. J Biol Chem. 2012 Jun 22;287(26):22206-15 |
Mir141 microRNA 141 (Synonyms: Mirn141, mmu-mir-141) | |
Results | Reference |
1* | J:160269 Michon F, Tummers M, Kyyronen M, Frilander MJ, Thesleff I, Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol. 2010 Apr 15;340(2):355-68 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
Mir142 microRNA 142 (Synonyms: miR-142, Mirn142, mmu-mir-142) | |
Results | Reference |
1 | J:290284 Shrestha A, Carraro G, Nottet N, Vazquez-Armendariz AI, Herold S, Cordero J, Singh I, Wilhelm J, Barreto G, Morty R, El Agha E, Mari B, Chen C, Zhang JS, Chao CM, Bellusci S, A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development. Cell Mol Life Sci. 2019 Jul;76(14):2817-2832 |
Mir143 microRNA 143 (Synonyms: Mirn143, mmu-mir-143) | |
Results | Reference |
1 | J:152702 Boettger T, Beetz N, Kostin S, Schneider J, Kruger M, Hein L, Braun T, Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster. J Clin Invest. 2009 Sep;119(9):2634-47 |
1* | J:146851 Hand NJ, Master ZR, Eauclaire SF, Weinblatt DE, Matthews RP, Friedman JR, The microRNA-30 family is required for vertebrate hepatobiliary development. Gastroenterology. 2009 Mar;136(3):1081-90 |
Mir145a microRNA 145a (Synonyms: Mirn145, mmu-mir-145, mmu-mir-145a) | |
Results | Reference |
1 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
Mir147 microRNA 147 (Synonyms: Mirn147, mmu-mir-147) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir148a microRNA 148a (Synonyms: Mirn148, Mirn148a, mmu-mir-148a) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir149 microRNA 149 (Synonyms: Mirn149, mmu-mir-149) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir152 microRNA 152 (Synonyms: Mirn152, mmu-mir-152) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir153 microRNA 153 (Synonyms: mir-153, Mirn153, mmu-mir-153) | |
Results | Reference |
1* | J:310005 Tsuyama J, Bunt J, Richards LJ, Iwanari H, Mochizuki Y, Hamakubo T, Shimazaki T, Okano H, MicroRNA-153 Regulates the Acquisition of Gliogenic Competence by Neural Stem Cells. Stem Cell Reports. 2015 Sep 8;5(3):365-77 |
Mir154 microRNA 154 (Synonyms: Mirn154, mmu-mir-154) | |
Results | Reference |
1* | J:305932 Chao CM, Carraro G, Rako ZA, Kolck J, Sedighi J, Zimmermann V, Moiseenko A, Wilhelm J, Young BM, Chong L, Wu J, Contreras A, Minoo P, Barreto G, Warburton D, Bellusci S, Failure to Down-Regulate miR-154 Expression in Early Postnatal Mouse Lung Epithelium Suppresses Alveologenesis, with Changes in Tgf-beta Signaling Similar to those Induced by Exposure to Hyperoxia. Cells. 2020 Apr 2;9(4):859 |
Mir181b-1 microRNA 181b-1 (Synonyms: mir 181b-1, Mirn181b-1, mmu-mir-181b-1) | |
Results | Reference |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir181b-2 microRNA 181b-2 (Synonyms: mir 181b-2, mir-181b-2, Mirn181b-2, mmu-mir-181b-2) | |
Results | Reference |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir182 microRNA 182 (Synonyms: Mirn182, mmu-mir-182) | |
Results | Reference |
1 | J:315409 Huyghe A, Van den Ackerveken P, Sacheli R, Prevot PP, Thelen N, Renauld J, Thiry M, Delacroix L, Nguyen L, Malgrange B, MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5. Cell Rep. 2015 Oct 6;13(1):31-42 |
1 | J:152506 Jin ZB, Hirokawa G, Gui L, Takahashi R, Osakada F, Hiura Y, Takahashi M, Yasuhara O, Iwai N, Targeted deletion of miR-182, an abundant retinal microRNA. Mol Vis. 2009;15:523-33 |
1 | J:223034 Krol J, Krol I, Alvarez CP, Fiscella M, Hierlemann A, Roska B, Filipowicz W, A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture. Nat Commun. 2015;6:7305 |
1* | J:169673 Weston MD, Pierce ML, Jensen-Smith HC, Fritzsch B, Rocha-Sanchez S, Beisel KW, Soukup GA, MicroRNA-183 family expression in hair cell development and requirement of microRNAs for hair cell maintenance and survival. Dev Dyn. 2011 Apr;240(4):808-19 |
Mir183 microRNA 183 (Synonyms: Mirn183, mmu-mir-183) | |
Results | Reference |
1 | J:223034 Krol J, Krol I, Alvarez CP, Fiscella M, Hierlemann A, Roska B, Filipowicz W, A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture. Nat Commun. 2015;6:7305 |
1* | J:163875 Wang XR, Zhang XM, Zhen J, Zhang PX, Xu G, Jiang H, MicroRNA expression in the embryonic mouse inner ear. Neuroreport. 2010 Jun 23;21(9):611-7 |
1* | J:169673 Weston MD, Pierce ML, Jensen-Smith HC, Fritzsch B, Rocha-Sanchez S, Beisel KW, Soukup GA, MicroRNA-183 family expression in hair cell development and requirement of microRNAs for hair cell maintenance and survival. Dev Dyn. 2011 Apr;240(4):808-19 |
Mir184 microRNA 184 (Synonyms: Mirn184, mmu-mir-184) | |
Results | Reference |
2 | J:251187 Gurha P, Chen X, Lombardi R, Willerson JT, Marian AJ, Knockdown of Plakophilin 2 Downregulates miR-184 Through CpG Hypermethylation and Suppression of the E2F1 Pathway and Leads to Enhanced Adipogenesis In Vitro. Circ Res. 2016 Sep 2;119(6):731-50 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir187 microRNA 187 (Synonyms: Mirn187, mmu-mir-187) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir194-1 microRNA 194-1 (Synonyms: Mirn194, Mirn194-1, mmu-mir-194-1) | |
Results | Reference |
1* | J:163875 Wang XR, Zhang XM, Zhen J, Zhang PX, Xu G, Jiang H, MicroRNA expression in the embryonic mouse inner ear. Neuroreport. 2010 Jun 23;21(9):611-7 |
Mir194-2 microRNA 194-2 (Synonyms: mir 194-2, Mirn194-2, mmu-mir-194-2) | |
Results | Reference |
1* | J:163875 Wang XR, Zhang XM, Zhen J, Zhang PX, Xu G, Jiang H, MicroRNA expression in the embryonic mouse inner ear. Neuroreport. 2010 Jun 23;21(9):611-7 |
Mir195a microRNA 195a (Synonyms: Mirn195, mmu-mir-195, mmu-mir-195a) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir196b microRNA 196b (Synonyms: mir 196b, Mirn196b, mmu-mir-196b) | |
Results | Reference |
1 | J:321428 Kruber P, Angay O, Winkler A, Bosl MR, Kneitz S, Heinze KG, Gessler M, Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation. Int J Cancer. 2019 Mar 15;144(6):1391-1400 |
Mir199a-1 microRNA 199a-1 (Synonyms: Mirn199, Mirn199a-1, mmu-mir-199a-1) | |
Results | Reference |
1 | J:148395 Friedman LM, Dror AA, Mor E, Tenne T, Toren G, Satoh T, Biesemeier DJ, Shomron N, Fekete DM, Hornstein E, Avraham KB, MicroRNAs are essential for development and function of inner ear hair cells in vertebrates. Proc Natl Acad Sci U S A. 2009 May 12;106(19):7915-20 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir199a-2 microRNA 199a-2 (Synonyms: mir 199a-2, Mirn199a-2, mmu-mir-199a-2) | |
Results | Reference |
1 | J:148395 Friedman LM, Dror AA, Mor E, Tenne T, Toren G, Satoh T, Biesemeier DJ, Shomron N, Fekete DM, Hornstein E, Avraham KB, MicroRNAs are essential for development and function of inner ear hair cells in vertebrates. Proc Natl Acad Sci U S A. 2009 May 12;106(19):7915-20 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir199b microRNA 199b (Synonyms: Mirn199b, mmu-mir-199b) | |
Results | Reference |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir200a microRNA 200a (Synonyms: Mirn200a, mmu-mir-200a) | |
Results | Reference |
1 | J:315409 Huyghe A, Van den Ackerveken P, Sacheli R, Prevot PP, Thelen N, Renauld J, Thiry M, Delacroix L, Nguyen L, Malgrange B, MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5. Cell Rep. 2015 Oct 6;13(1):31-42 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
Mir200b microRNA 200b (Synonyms: Mirn200b, mmu-mir-200b) | |
Results | Reference |
1 | J:315409 Huyghe A, Van den Ackerveken P, Sacheli R, Prevot PP, Thelen N, Renauld J, Thiry M, Delacroix L, Nguyen L, Malgrange B, MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5. Cell Rep. 2015 Oct 6;13(1):31-42 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
Mir200c microRNA 200c (Synonyms: mir 200c, Mirn200c, mmu-mir-200c) | |
Results | Reference |
1 | J:315409 Huyghe A, Van den Ackerveken P, Sacheli R, Prevot PP, Thelen N, Renauld J, Thiry M, Delacroix L, Nguyen L, Malgrange B, MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5. Cell Rep. 2015 Oct 6;13(1):31-42 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
1* | J:163875 Wang XR, Zhang XM, Zhen J, Zhang PX, Xu G, Jiang H, MicroRNA expression in the embryonic mouse inner ear. Neuroreport. 2010 Jun 23;21(9):611-7 |
Mir204 microRNA 204 (Synonyms: Mirn204, mmu-mir-204) | |
Results | Reference |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir205 microRNA 205 (Synonyms: Mirn205, mmu-mir-205) | |
Results | Reference |
1* | J:243203 Farmer DT, Finley JK, Chen FY, Tarifeno-Saldivia E, McNamara NA, Knox SM, McManus MT, miR-205 is a critical regulator of lacrimal gland development. Dev Biol. 2017 Jul 01;427(1):12-20 |
1 | J:292559 Wilhide ME, Feller JD, Li B, Mohamed AZ, Becknell B, Jackson AR, McHugh KM, Ingraham SE, Renal epithelial miR-205 expression correlates with disease severity in a mouse model of congenital obstructive nephropathy. Pediatr Res. 2016 Oct;80(4):602-9 |
Mir206 microRNA 206 (Synonyms: Mirn206, mmu-mir-206) | |
Results | Reference |
1 | J:155543 Inose H, Ochi H, Kimura A, Fujita K, Xu R, Sato S, Iwasaki M, Sunamura S, Takeuchi Y, Fukumoto S, Saito K, Nakamura T, Siomi H, Ito H, Arai Y, Shinomiya K, Takeda S, A microRNA regulatory mechanism of osteoblast differentiation. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20794-9 |
1 | J:177268 Radzikinas K, Aven L, Jiang Z, Tran T, Paez-Cortez J, Boppidi K, Lu J, Fine A, Ai X, A Shh/miR-206/BDNF Cascade Coordinates Innervation and Formation of Airway Smooth Muscle. J Neurosci. 2011 Oct 26;31(43):15407-15 |
Mir208a microRNA 208a (Synonyms: mir-208, Mirn208, Mirn208a, mmu-mir-208, mmu-mir-208a) | |
Results | Reference |
1* | J:152696 Callis TE, Pandya K, Seok HY, Tang RH, Tatsuguchi M, Huang ZP, Chen JF, Deng Z, Gunn B, Shumate J, Willis MS, Selzman CH, Wang DZ, MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest. 2009 Sep;119(9):2772-86 |
1 | J:131962 Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ, Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2111-6 |
1 | J:147774 Ikeda S, He A, Kong SW, Lu J, Bejar R, Bodyak N, Lee KH, Ma Q, Kang PM, Golub TR, Pu WT, MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol. 2009 Apr;29(8):2193-204 |
Mir208b microRNA 208b (Synonyms: Mirn208b, mmu-mir-208b) | |
Results | Reference |
1* | J:152696 Callis TE, Pandya K, Seok HY, Tang RH, Tatsuguchi M, Huang ZP, Chen JF, Deng Z, Gunn B, Shumate J, Willis MS, Selzman CH, Wang DZ, MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest. 2009 Sep;119(9):2772-86 |
1 | J:131962 Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ, Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2111-6 |
1 | J:147774 Ikeda S, He A, Kong SW, Lu J, Bejar R, Bodyak N, Lee KH, Ma Q, Kang PM, Golub TR, Pu WT, MicroRNA-1 negatively regulates expression of the hypertrophy-associated calmodulin and Mef2a genes. Mol Cell Biol. 2009 Apr;29(8):2193-204 |
Mir211 microRNA 211 (Synonyms: Mirn211, mmu-mir-211) | |
Results | Reference |
1* | J:312812 Fan C, Wu Q, Ye X, Luo H, Yan D, Xiong Y, Zhu H, Diao Y, Zhang W, Wan J, Role of miR-211 in Neuronal Differentiation and Viability: Implications to Pathogenesis of Alzheimer's Disease. Front Aging Neurosci. 2016;8:166 |
Mir214 microRNA 214 (Synonyms: Mirn214, miRNA019, mmu-mir-214) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir216a microRNA 216a (Synonyms: Mirn216, Mirn216a, mmu-mir-216a) | |
Results | Reference |
1 | J:285877 Azevedo-Pouly AC, Sutaria DS, Jiang J, Elgamal OA, Amari F, Allard D, Grippo PJ, Coppola V, Schmittgen TD, miR-216 and miR-217 expression is reduced in transgenic mouse models of pancreatic adenocarcinoma, knockout of miR-216/miR-217 host gene is embryonic lethal. Funct Integr Genomics. 2017 May;17(2-3):203-212 |
1* | J:268850 Wang J, Chen X, Shen D, Ge D, Chen J, Pei J, Li Y, Yue Z, Feng J, Chu M, Nie Y, A long noncoding RNA NR_045363 controls cardiomyocyte proliferation and cardiac repair. J Mol Cell Cardiol. 2018 Dec 13;127:105-114 |
Mir216b microRNA 216b (Synonyms: Mirn216b, mmu-mir-216b) | |
Results | Reference |
1 | J:285877 Azevedo-Pouly AC, Sutaria DS, Jiang J, Elgamal OA, Amari F, Allard D, Grippo PJ, Coppola V, Schmittgen TD, miR-216 and miR-217 expression is reduced in transgenic mouse models of pancreatic adenocarcinoma, knockout of miR-216/miR-217 host gene is embryonic lethal. Funct Integr Genomics. 2017 May;17(2-3):203-212 |
Mir217 microRNA 217 (Synonyms: Mirn217, mmu-mir-217) | |
Results | Reference |
1 | J:285877 Azevedo-Pouly AC, Sutaria DS, Jiang J, Elgamal OA, Amari F, Allard D, Grippo PJ, Coppola V, Schmittgen TD, miR-216 and miR-217 expression is reduced in transgenic mouse models of pancreatic adenocarcinoma, knockout of miR-216/miR-217 host gene is embryonic lethal. Funct Integr Genomics. 2017 May;17(2-3):203-212 |
Mir218-1 microRNA 218-1 (Synonyms: mir 218-1, mir-218-1, Mirn218-1, mmu-mir-218-1) | |
Results | Reference |
1* | J:156732 Simion A, Laudadio I, Prevot PP, Raynaud P, Lemaigre FP, Jacquemin P, MiR-495 and miR-218 regulate the expression of the Onecut transcription factors HNF-6 and OC-2. Biochem Biophys Res Commun. 2010 Jan 1;391(1):293-8 |
1 | J:299725 Wang X, Liu J, Yin W, Abdi F, Pang PD, Fucci QA, Abbott M, Chang SL, Steele G, Patel A, Mori Y, Zhang A, Zhu S, Lu TS, Kibel AS, Wang B, Lim K, Siedlecki AM, miR-218 Expressed in Endothelial Progenitor Cells Contributes to the Development and Repair of the Kidney Microvasculature. Am J Pathol. 2020 Mar;190(3):642-659 |
Mir218-2 microRNA 218-2 (Synonyms: mir 218-2, mir-218-2, Mirn218-2, mmu-mir-218-2) | |
Results | Reference |
1* | J:156732 Simion A, Laudadio I, Prevot PP, Raynaud P, Lemaigre FP, Jacquemin P, MiR-495 and miR-218 regulate the expression of the Onecut transcription factors HNF-6 and OC-2. Biochem Biophys Res Commun. 2010 Jan 1;391(1):293-8 |
1 | J:299725 Wang X, Liu J, Yin W, Abdi F, Pang PD, Fucci QA, Abbott M, Chang SL, Steele G, Patel A, Mori Y, Zhang A, Zhu S, Lu TS, Kibel AS, Wang B, Lim K, Siedlecki AM, miR-218 Expressed in Endothelial Progenitor Cells Contributes to the Development and Repair of the Kidney Microvasculature. Am J Pathol. 2020 Mar;190(3):642-659 |
Mir221 microRNA 221 (Synonyms: mir 221, Mirn221, mmu-mir-221) | |
Results | Reference |
1 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
2* | J:199420 Mujahid S, Nielsen HC, Volpe MV, MiR-221 and miR-130a regulate lung airway and vascular development. PLoS One. 2013;8(2):e55911 |
Mir223 microRNA 223 (Synonyms: miR-223, Mirn223, mmu-mir-223) | |
Results | Reference |
1* | J:200897 Glasgow SM, Laug D, Brawley VS, Zhang Z, Corder A, Yin Z, Wong ST, Li XN, Foster AE, Ahmed N, Deneen B, The miR-223/Nuclear Factor I-A Axis Regulates Glial Precursor Proliferation and Tumorigenesis in the CNS. J Neurosci. 2013 Aug 14;33(33):13560-13568 |
1* | J:146851 Hand NJ, Master ZR, Eauclaire SF, Weinblatt DE, Matthews RP, Friedman JR, The microRNA-30 family is required for vertebrate hepatobiliary development. Gastroenterology. 2009 Mar;136(3):1081-90 |
Mir223hg Mir223 host gene (Synonyms: ENSMUSG00000065522, F630028O10Rik, Gm14924, lnc15847) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Mir301 microRNA 301 (Synonyms: mir 301, Mirn301, mmu-mir-301, mmu-mir-301a) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir302a microRNA 302a (Synonyms: mir 302, Mirn302a, mmu-mir-302, mmu-mir-302a) | |
Results | Reference |
1 | J:171513 Tian Y, Zhang Y, Hurd L, Hannenhalli S, Liu F, Lu MM, Morrisey EE, Regulation of lung endoderm progenitor cell behavior by miR302/367. Development. 2011 Apr;138(7):1235-45 |
Mir302b microRNA 302b (Synonyms: mir 302b, Mirn302b, mmu-mir-302b) | |
Results | Reference |
1 | J:171513 Tian Y, Zhang Y, Hurd L, Hannenhalli S, Liu F, Lu MM, Morrisey EE, Regulation of lung endoderm progenitor cell behavior by miR302/367. Development. 2011 Apr;138(7):1235-45 |
Mir302c microRNA 302c (Synonyms: mir 302c, Mirn302c, mmu-mir-302c) | |
Results | Reference |
1 | J:171513 Tian Y, Zhang Y, Hurd L, Hannenhalli S, Liu F, Lu MM, Morrisey EE, Regulation of lung endoderm progenitor cell behavior by miR302/367. Development. 2011 Apr;138(7):1235-45 |
Mir302d microRNA 302d (Synonyms: mir 302d, Mirn302d, mmu-mir-302d) | |
Results | Reference |
1 | J:171513 Tian Y, Zhang Y, Hurd L, Hannenhalli S, Liu F, Lu MM, Morrisey EE, Regulation of lung endoderm progenitor cell behavior by miR302/367. Development. 2011 Apr;138(7):1235-45 |
Mir326 microRNA 326 (Synonyms: mir 326, Mirn326, mmu-mir-326) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir331 microRNA 331 (Synonyms: mir 331, Mirn331, mmu-mir-331) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir335 microRNA 335 (Synonyms: mir 335, mir-335, Mirn335, mmu-mir-335) | |
Results | Reference |
1 | J:315409 Huyghe A, Van den Ackerveken P, Sacheli R, Prevot PP, Thelen N, Renauld J, Thiry M, Delacroix L, Nguyen L, Malgrange B, MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5. Cell Rep. 2015 Oct 6;13(1):31-42 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir338 microRNA 338 (Synonyms: mir 338, Mirn338, mmu-mir-338) | |
Results | Reference |
1 | J:339746 Jin R, Zhang H, Lin C, Guo J, Zou W, Chen Z, Liu H, Inhibition of miR338 rescues cleidocranial dysplasia in Runx2 mutant mice partially via the Hif1a-Vegfa axis. Exp Mol Med. 2023 Jan;55(1):69-80 |
1* | J:321238 Kos A, de Mooij-Malsen AJ, van Bokhoven H, Kaplan BB, Martens GJ, Kolk SM, Aschrafi A, MicroRNA-338 modulates cortical neuronal placement and polarity. RNA Biol. 2017 Jul 3;14(7):905-913 |
Mir342 microRNA 342 (Synonyms: mir 342, Mirn342, mmu-mir-342) | |
Results | Reference |
1* | J:313935 Fishman ES, Louie M, Miltner AM, Cheema SK, Wong J, Schlaeger NM, Moshiri A, Simo S, Tarantal AF, La Torre A, MicroRNA Signatures of the Developing Primate Fovea. Front Cell Dev Biol. 2021;9:654385 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir346 microRNA 346 (Synonyms: mir 346, Mirn346, mmu-mir-346) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir365-1 microRNA 365-1 (Synonyms: mir 365-1, Mirn365-1, mmu-mir-365-1) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir365-2 microRNA 365-2 (Synonyms: mir 365-2, Mirn365-2, mmu-mir-365-2) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Mir367 microRNA 367 (Synonyms: mir 367, Mirn367, mmu-mir-367) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1 | J:171513 Tian Y, Zhang Y, Hurd L, Hannenhalli S, Liu F, Lu MM, Morrisey EE, Regulation of lung endoderm progenitor cell behavior by miR302/367. Development. 2011 Apr;138(7):1235-45 |
Mir381 microRNA 381 (Synonyms: mir 381, Mirn381, mmu-mir-381) | |
Results | Reference |
1* | J:311442 Chen W, Sheng P, Huang Z, Meng F, Kang Y, Huang G, Zhang Z, Liao W, Zhang Z, MicroRNA-381 Regulates Chondrocyte Hypertrophy by Inhibiting Histone Deacetylase 4 Expression. Int J Mol Sci. 2016 Aug 23;17(9):1377 |
Mir410 microRNA 410 (Synonyms: mir 410, Mirn410, mmu-mir-410) | |
Results | Reference |
1* | J:146851 Hand NJ, Master ZR, Eauclaire SF, Weinblatt DE, Matthews RP, Friedman JR, The microRNA-30 family is required for vertebrate hepatobiliary development. Gastroenterology. 2009 Mar;136(3):1081-90 |
1* | J:166176 Zhou Y, Cheunsuchon P, Nakayama Y, Lawlor MW, Zhong Y, Rice KA, Zhang L, Zhang X, Gordon FE, Lidov HG, Bronson RT, Klibanski A, Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. Development. 2010 Aug;137(16):2643-52 |
Mir429 microRNA 429 (Synonyms: mir 429, Mirn429, mmu-mir-429) | |
Results | Reference |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
Mir431 microRNA 431 (Synonyms: mir 431, Mirn431, mmu-mir-431) | |
Results | Reference |
1* | J:224145 Ito M, Sferruzzi-Perri AN, Edwards CA, Adalsteinsson BT, Allen SE, Loo TH, Kitazawa M, Kaneko-Ishino T, Ishino F, Stewart CL, Ferguson-Smith AC, A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development. Development. 2015 Jul 15;142(14):2425-30 |
Mir433 microRNA 433 (Synonyms: mir 433, Mirn433, mmu-mir-433) | |
Results | Reference |
1* | J:224145 Ito M, Sferruzzi-Perri AN, Edwards CA, Adalsteinsson BT, Allen SE, Loo TH, Kitazawa M, Kaneko-Ishino T, Ishino F, Stewart CL, Ferguson-Smith AC, A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development. Development. 2015 Jul 15;142(14):2425-30 |
Mir434 microRNA 434 (Synonyms: mir 434, Mirn434, mmu-mir-434) | |
Results | Reference |
1* | J:224145 Ito M, Sferruzzi-Perri AN, Edwards CA, Adalsteinsson BT, Allen SE, Loo TH, Kitazawa M, Kaneko-Ishino T, Ishino F, Stewart CL, Ferguson-Smith AC, A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development. Development. 2015 Jul 15;142(14):2425-30 |
Mir449a microRNA 449a (Synonyms: mir 449, Mirn449a, mmu-mir-449a) | |
Results | Reference |
1 | J:133461 Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH, Schier AF, Dulac C, Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 2008 Jan 10;57(1):41-55 |
1* | J:305376 Li B, Wang Z, Yang F, Huang J, Hu X, Deng S, Tian M, Si X, miR449a5p suppresses CDK6 expression to inhibit cardiomyocyte proliferation. Mol Med Rep. 2021 Jan;23(1) |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir449b microRNA 449b (Synonyms: Mirn449b, mmu-mir-449b) | |
Results | Reference |
1 | J:133461 Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH, Schier AF, Dulac C, Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 2008 Jan 10;57(1):41-55 |
Mir449c microRNA 449c (Synonyms: microRNA 449c, Mirn449c, mmu-mir-449c) | |
Results | Reference |
1 | J:133461 Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH, Schier AF, Dulac C, Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 2008 Jan 10;57(1):41-55 |
Mir451a microRNA 451a (Synonyms: mir 451, Mirn451, mmu-mir-451, mmu-mir-451a) | |
Results | Reference |
1* | J:163418 Rasmussen KD, Simmini S, Abreu-Goodger C, Bartonicek N, Di Giacomo M, Bilbao-Cortes D, Horos R, Von Lindern M, Enright AJ, O'Carroll D, The miR-144/451 locus is required for erythroid homeostasis. J Exp Med. 2010 Jul 5;207(7):1351-8 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir455 microRNA 455 (Synonyms: mir 455, Mirn455, mmu-mir-455) | |
Results | Reference |
1 | J:251599 Chen W, Chen L, Zhang Z, Meng F, Huang G, Sheng P, Zhang Z, Liao W, MicroRNA-455-3p modulates cartilage development and degeneration through modification of histone H3 acetylation. Biochim Biophys Acta. 2016 Dec;1863(12):2881-2891 |
1* | J:289776 Mao G, Kang Y, Lin R, Hu S, Zhang Z, Li H, Liao W, Zhang Z, Long Non-coding RNA HOTTIP Promotes CCL3 Expression and Induces Cartilage Degradation by Sponging miR-455-3p. Front Cell Dev Biol. 2019;7:161 |
Mir484 microRNA 484 (Synonyms: mir 484, Mirn484, mmu-mir-484) | |
Results | Reference |
1 | J:303388 Fujitani M, Zhang S, Fujiki R, Fujihara Y, Yamashita T, A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling. Mol Psychiatry. 2017 Mar;22(3):364-374 |
Mir494 microRNA 494 (Synonyms: mir 494, Mirn494, mmu-mir-494) | |
Results | Reference |
1* | J:359452 Pang Y, Ruan X, Liu W, Hou L, Yin B, Shu P, Peng X, MicroRNA-495 Modulates Neuronal Layer Fate Determination by Targeting Tcf4. Int J Biol Sci. 2024;20(15):6207-6221 |
Mir495 microRNA 495 (Synonyms: mir 495, Mirn495, miRNA102, mmu-mir-495) | |
Results | Reference |
1* | J:359452 Pang Y, Ruan X, Liu W, Hou L, Yin B, Shu P, Peng X, MicroRNA-495 Modulates Neuronal Layer Fate Determination by Targeting Tcf4. Int J Biol Sci. 2024;20(15):6207-6221 |
1* | J:156732 Simion A, Laudadio I, Prevot PP, Raynaud P, Lemaigre FP, Jacquemin P, MiR-495 and miR-218 regulate the expression of the Onecut transcription factors HNF-6 and OC-2. Biochem Biophys Res Commun. 2010 Jan 1;391(1):293-8 |
Mir497 microRNA 497 (Synonyms: Mirn497, mmu-mir-497) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
Mir503 microRNA 503 (Synonyms: mir 503, Mirn503, mmu-mir-503) | |
Results | Reference |
1 | J:344870 Zhou Y, Liu K, Tang W, Zhang Y, Sun Y, Wu Y, Shi Y, Yao Z, Li Y, Bai R, Liang R, Sun P, Chang X, Wang S, Zhu Y, Han X, beta-Cell miRNA-503-5p Induced by Hypomethylation and Inflammation Promotes Insulin Resistance and beta-Cell Decompensation. Diabetes. 2024 Jan 1;73(1):57-74 |
Mir582 microRNA 582 (Synonyms: Mirn582, mmu-mir-582) | |
Results | Reference |
1 | J:325358 Zhang YF, Li XX, Cao XL, Ji CC, Gao XY, Gao D, Han H, Yu F, Zheng MH, MicroRNA-582-5p Contributes to the Maintenance of Neural Stem Cells Through Inhibiting Secretory Protein FAM19A1. Front Cell Neurosci. 2022;16:866020 |
Mir592 microRNA 592 (Synonyms: mir 592, mir-592, Mirn592, mmu-mir-592) | |
Results | Reference |
2 | J:323615 Fu Y, Zhou Y, Zhang YL, Zhao B, Zhang XL, Zhang WT, Lu YJ, Lu A, Zhang J, Zhang J, Loss of neurodevelopmental-associated miR-592 impairs neurogenesis and causes social interaction deficits. Cell Death Dis. 2022 Apr 1;13(4):292 |
Mir667 microRNA 667 (Synonyms: Mirn667, mmir 667, mmu-mir-667) | |
Results | Reference |
1* | J:359452 Pang Y, Ruan X, Liu W, Hou L, Yin B, Shu P, Peng X, MicroRNA-495 Modulates Neuronal Layer Fate Determination by Targeting Tcf4. Int J Biol Sci. 2024;20(15):6207-6221 |
Mir675 microRNA 675 (Synonyms: mir 675, mir-675, Mirn675, mmu-mir-675) | |
Results | Reference |
1 | J:335099 Naing BT, Takizawa T, Sakurai T, Kyi-Tha-Thu C, Takizawa T, Possible transfer of lncRNA H19-derived miRNA miR-675-3p to adjacent H19-non-expressing trophoblast cells in near-term mouse placenta. Histochem Cell Biol. 2023 Apr;159(4):363-375 |
1* | J:230499 Wang S, Wu X, Liu Y, Yuan J, Yang F, Huang J, Meng Q, Zhou C, Liu F, Ma J, Sun S, Zheng J, Wang F, Long noncoding RNA H19 inhibits the proliferation of fetal liver cells and the Wnt signaling pathway. FEBS Lett. 2016 Feb;590(4):559-70 |
Mir708 microRNA 708 (Synonyms: mir 708, Mirn708, mmu-mir-708) | |
Results | Reference |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir712 microRNA 712 (Synonyms: Mirn712, mmu-mir-712) | |
Results | Reference |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir875 microRNA 875 (Synonyms: Mirn875, mmu-mir-875) | |
Results | Reference |
1* | J:160269 Michon F, Tummers M, Kyyronen M, Frilander MJ, Thesleff I, Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol. 2010 Apr 15;340(2):355-68 |
Mir3065 microRNA 3065 (Synonyms: mmu-mir-3065) | |
Results | Reference |
1 | J:339746 Jin R, Zhang H, Lin C, Guo J, Zou W, Chen Z, Liu H, Inhibition of miR338 rescues cleidocranial dysplasia in Runx2 mutant mice partially via the Hif1a-Vegfa axis. Exp Mol Med. 2023 Jan;55(1):69-80 |
Mir5130 microRNA 5130 (Synonyms: mmu-mir-5130) | |
Results | Reference |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
Mir6402 microRNA 6402 (Synonyms: mmu-mir-6402) | |
Results | Reference |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
Mir7210 microRNA 7210 (Synonyms: mmu-mir-7210) | |
Results | Reference |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
Mirc35hg microRNA cluster 35, host gene (Synonyms: linc_miR96) | |
Results | Reference |
1* | J:193822 Lumayag S, Haldin CE, Corbett NJ, Wahlin KJ, Cowan C, Turturro S, Larsen PE, Kovacs B, Witmer PD, Valle D, Zack DJ, Nicholson DA, Xu S, Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):E507-16 |
1* | J:258363 Ushakov K, Koffler-Brill T, Rom A, Perl K, Ulitsky I, Avraham KB, Genome-wide identification and expression profiling of long non-coding RNAs in auditory and vestibular systems. Sci Rep. 2017 Aug 17;7(1):8637 |
Mirg miRNA containing gene (Synonyms: 2810474H01Rik, Gm2928, Meg9, Mirg) | |
Results | Reference |
1* | J:181051 Han Z, He H, Zhang F, Huang Z, Liu Z, Jiang H, Wu Q, Spatiotemporal expression pattern of Mirg, an imprinted non-coding gene, during mouse embryogenesis. J Mol Histol. 2012 Feb;43(1):1-8 |
1* | J:299191 Kitazawa M, Hayashi S, Imamura M, Takeda S, Oishi Y, Kaneko-Ishino T, Ishino F, Deficiency and overexpression of Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Kagami-Ogata syndromes. Development. 2020 Sep 2;147(21):dev185918 |
1 | J:216177 Labialle S, Marty V, Bortolin-Cavaille ML, Hoareau-Osman M, Pradere JP, Valet P, Martin PG, Cavaille J, The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation. EMBO J. 2014 Oct 1;33(19):2216-30 |
1 | J:108133 Sekita Y, Wagatsuma H, Irie M, Kobayashi S, Kohda T, Matsuda J, Yokoyama M, Ogura A, Schuster-Gossler K, Gossler A, Ishino F, Kaneko-Ishino T, Aberrant regulation of imprinted gene expression in Gtl2lacZ mice. Cytogenet Genome Res. 2006;113(1-4):223-9 |
2* | J:105770 Tierling S, Dalbert S, Schoppenhorst S, Tsai CE, Oliger S, Ferguson-Smith AC, Paulsen M, Walter J, High-resolution map and imprinting analysis of the Gtl2-Dnchc1 domain on mouse chromosome 12. Genomics. 2006 Feb;87(2):225-35 |
1* | J:166176 Zhou Y, Cheunsuchon P, Nakayama Y, Lawlor MW, Zhong Y, Rice KA, Zhang L, Zhang X, Gordon FE, Lidov HG, Bronson RT, Klibanski A, Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. Development. 2010 Aug;137(16):2643-52 |
Mirlet7a-1 microRNA let7a-1 (Synonyms: Let-7a, Mirnlet7a, Mirnlet7a-1, mmu-let-7a-1) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1 | J:178118 Li Q, Bian S, Hong J, Kawase-Koga Y, Zhu E, Zheng Y, Yang L, Sun T, Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development. PLoS One. 2011;6(10):e26000 |
1 | J:321070 Osborne JK, Kinney MA, Han A, Akinnola KE, Yermalovich AV, Vo LT, Pearson DS, Sousa PM, Ratanasirintrawoot S, Tsanov KM, Barragan J, North TE, Metzger RJ, Daley GQ, Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021 Jul 20;36(3):109408 |
1 | J:270550 Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ, Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan 11;10(1):168 |
Mirlet7a-2 microRNA let7a-2 (Synonyms: let 7a-2, Mirnlet7a-2, mmu-let-7a-2) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1 | J:178118 Li Q, Bian S, Hong J, Kawase-Koga Y, Zhu E, Zheng Y, Yang L, Sun T, Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development. PLoS One. 2011;6(10):e26000 |
1 | J:321070 Osborne JK, Kinney MA, Han A, Akinnola KE, Yermalovich AV, Vo LT, Pearson DS, Sousa PM, Ratanasirintrawoot S, Tsanov KM, Barragan J, North TE, Metzger RJ, Daley GQ, Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021 Jul 20;36(3):109408 |
1 | J:270550 Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ, Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan 11;10(1):168 |
Mirlet7b microRNA let7b (Synonyms: Mirnlet7b, mmu-let-7b) | |
Results | Reference |
1 | J:321070 Osborne JK, Kinney MA, Han A, Akinnola KE, Yermalovich AV, Vo LT, Pearson DS, Sousa PM, Ratanasirintrawoot S, Tsanov KM, Barragan J, North TE, Metzger RJ, Daley GQ, Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021 Jul 20;36(3):109408 |
1 | J:188151 Repetto E, Briata P, Kuziner N, Harfe BD, McManus MT, Gherzi R, Rosenfeld MG, Trabucchi M, Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP. PLoS Genet. 2012 Jul;8(7):e1002823 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
1 | J:283783 Shu P, Wu C, Ruan X, Liu W, Hou L, Fu H, Wang M, Liu C, Zeng Y, Chen P, Yin B, Yuan J, Qiang B, Peng X, Zhong W, Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell. 2019 Jun 3;49(5):764-785.e4 |
1 | J:270550 Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ, Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan 11;10(1):168 |
Mirlet7c-1 microRNA let7c-1 (Synonyms: Mirnlet7c, Mirnlet7c-1, mmu-let-7c-1) | |
Results | Reference |
1 | J:321070 Osborne JK, Kinney MA, Han A, Akinnola KE, Yermalovich AV, Vo LT, Pearson DS, Sousa PM, Ratanasirintrawoot S, Tsanov KM, Barragan J, North TE, Metzger RJ, Daley GQ, Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021 Jul 20;36(3):109408 |
1 | J:188151 Repetto E, Briata P, Kuziner N, Harfe BD, McManus MT, Gherzi R, Rosenfeld MG, Trabucchi M, Let-7b/c enhance the stability of a tissue-specific mRNA during mammalian organogenesis as part of a feedback loop involving KSRP. PLoS Genet. 2012 Jul;8(7):e1002823 |
1* | J:102849 Schulman BR, Esquela-Kerscher A, Slack FJ, Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis. Dev Dyn. 2005 Dec;234(4):1046-54 |
1 | J:283783 Shu P, Wu C, Ruan X, Liu W, Hou L, Fu H, Wang M, Liu C, Zeng Y, Chen P, Yin B, Yuan J, Qiang B, Peng X, Zhong W, Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell. 2019 Jun 3;49(5):764-785.e4 |
1 | J:270550 Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ, Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan 11;10(1):168 |
Mirlet7c-2 microRNA let7c-2 (Synonyms: let 7c-2, Mirnlet7c-2, mmu-let-7c-2) | |
Results | Reference |
1 | J:321070 Osborne JK, Kinney MA, Han A, Akinnola KE, Yermalovich AV, Vo LT, Pearson DS, Sousa PM, Ratanasirintrawoot S, Tsanov KM, Barragan J, North TE, Metzger RJ, Daley GQ, Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021 Jul 20;36(3):109408 |
1* | J:102849 Schulman BR, Esquela-Kerscher A, Slack FJ, Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis. Dev Dyn. 2005 Dec;234(4):1046-54 |
1 | J:270550 Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ, Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan 11;10(1):168 |
Mirlet7d microRNA let7d (Synonyms: Mirnlet7d, mmu-let-7d) | |
Results | Reference |
1* | J:297771 Fairchild CLA, Cheema SK, Wong J, Hino K, Simo S, La Torre A, Let-7 regulates cell cycle dynamics in the developing cerebral cortex and retina. Sci Rep. 2019 Oct 25;9(1):15336 |
1 | J:321070 Osborne JK, Kinney MA, Han A, Akinnola KE, Yermalovich AV, Vo LT, Pearson DS, Sousa PM, Ratanasirintrawoot S, Tsanov KM, Barragan J, North TE, Metzger RJ, Daley GQ, Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021 Jul 20;36(3):109408 |
1 | J:270550 Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ, Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan 11;10(1):168 |
Mirlet7e microRNA let7e (Synonyms: Mirnlet7e, mmu-let-7e) | |
Results | Reference |
1 | J:321070 Osborne JK, Kinney MA, Han A, Akinnola KE, Yermalovich AV, Vo LT, Pearson DS, Sousa PM, Ratanasirintrawoot S, Tsanov KM, Barragan J, North TE, Metzger RJ, Daley GQ, Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021 Jul 20;36(3):109408 |
1 | J:270550 Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ, Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan 11;10(1):168 |
Mirlet7f-1 microRNA let7f-1 (Synonyms: Mirnlet7f1, mmu-let-7f-1) | |
Results | Reference |
1 | J:321070 Osborne JK, Kinney MA, Han A, Akinnola KE, Yermalovich AV, Vo LT, Pearson DS, Sousa PM, Ratanasirintrawoot S, Tsanov KM, Barragan J, North TE, Metzger RJ, Daley GQ, Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021 Jul 20;36(3):109408 |
1 | J:270550 Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ, Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan 11;10(1):168 |
Mirlet7f-2 microRNA let7f-2 (Synonyms: Mirnlet7f2, mmu-let-7f-2) | |
Results | Reference |
1 | J:321070 Osborne JK, Kinney MA, Han A, Akinnola KE, Yermalovich AV, Vo LT, Pearson DS, Sousa PM, Ratanasirintrawoot S, Tsanov KM, Barragan J, North TE, Metzger RJ, Daley GQ, Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021 Jul 20;36(3):109408 |
1 | J:270550 Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ, Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan 11;10(1):168 |
Mirlet7g microRNA let7g (Synonyms: Mirnlet7g, mmu-let-7g) | |
Results | Reference |
1* | J:176480 Eda A, Takahashi M, Fukushima T, Hohjoh H, Alteration of microRNA expression in the process of mouse brain growth. Gene. 2011 Oct 1;485(1):46-52 |
1 | J:321070 Osborne JK, Kinney MA, Han A, Akinnola KE, Yermalovich AV, Vo LT, Pearson DS, Sousa PM, Ratanasirintrawoot S, Tsanov KM, Barragan J, North TE, Metzger RJ, Daley GQ, Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021 Jul 20;36(3):109408 |
1 | J:270550 Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ, Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan 11;10(1):168 |
Mirlet7i microRNA let7i (Synonyms: Mirnlet7i, mmu-let-7i) | |
Results | Reference |
1 | J:321070 Osborne JK, Kinney MA, Han A, Akinnola KE, Yermalovich AV, Vo LT, Pearson DS, Sousa PM, Ratanasirintrawoot S, Tsanov KM, Barragan J, North TE, Metzger RJ, Daley GQ, Lin28 paralogs regulate lung branching morphogenesis. Cell Rep. 2021 Jul 20;36(3):109408 |
1 | J:270550 Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ, Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan 11;10(1):168 |
Mitf melanogenesis associated transcription factor (Synonyms: BCC2, bHLHe32, Gsfbcc2, mi, wh) | |
Results | Reference |
1* | J:50809 Bora N, Conway SJ, Liang H, Smith SB, Transient overexpression of the Microphthalmia gene in the eyes of Microphthalmia vitiligo mutant mice. Dev Dyn. 1998 Nov;213(3):283-92 |
1 | J:287985 Bosze B, Moon MS, Kageyama R, Brown NL, Simultaneous Requirements for Hes1 in Retinal Neurogenesis and Optic Cup-Stalk Boundary Maintenance. J Neurosci. 2020 Feb 12;40(7):1501-1513 |
1 | J:181435 Gupta D, Harvey SA, Kaminski N, Swamynathan SK, Mouse conjunctival forniceal gene expression during postnatal development and its regulation by Kruppel-like factor 4. Invest Ophthalmol Vis Sci. 2011 Jul;52(8):4951-62 |
1* | J:13562 Hodgkinson CA, Moore KJ, Nakayama A, Steingrimsson E, Copeland NG, Jenkins NA, Arnheiter H, Mutations at the mouse microphthalmia locus are associated with defects in a gene encoding a novel basic-helix-loop-helix-zipper protein. Cell. 1993 Jul 30;74(2):395-404 |
1* | J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347 |
1 | J:306330 Le D, Lim S, Min KW, Park JW, Kim Y, Ha T, Moon KH, Wagner KU, Kim JW, Tsg101 Is Necessary for the Establishment and Maintenance of Mouse Retinal Pigment Epithelial Cell Polarity. Mol Cells. 2021 Mar 31;44(3):168-178 |
1 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
1* | J:46130 Nakayama A, Nguyen MT, Chen CC, Opdecamp K, Hodgkinson CA, Arnheiter H, Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently. Mech Dev. 1998 Jan;70(1-2):155-66 |
1 | J:357839 Nasim S, Abujamra BA, Chaparro D, Nogueira PDS, Riva A, Hutcheson JD, Kos L, Multiple cell types including melanocytes contribute to elastogenesis in the developing murine aortic valve. Sci Rep. 2024 Oct 26;14(1):25481 |
1 | J:173055 Stolt CC, Lommes P, Hillgartner S, Wegner M, The transcription factor Sox5 modulates Sox10 function during melanocyte development. Nucleic Acids Res. 2008 Oct;36(17):5427-40 |
1 | J:141138 Zhang Y, Burgess D, Overbeek PA, Govindarajan V, Dominant inhibition of lens placode formation in mice. Dev Biol. 2008 Nov 1;323(1):53-63 |
Mixl1 Mix paired-like homeobox (Synonyms: Mml) | |
Results | Reference |
1* | J:65842 Robb L, Hartley L, Begley CG, Brodnicki TC, Copeland NG, Gilbert DJ, Jenkins NA, Elefanty AG, Cloning, expression analysis, and chromosomal localization of murine and human homologues of a xenopus mix gene. Dev Dyn. 2000 Dec;219(4):497-504 |
Mki67 antigen identified by monoclonal antibody Ki 67 (Synonyms: D630048A14Rik, Ki-67, Ki67) | |
Results | Reference |
1 | J:344365 Abad C, Robayo MC, Muniz-Moreno MDM, Bernardi MT, Otero MG, Kosanovic C, Griswold AJ, Pierson TM, Walz K, Young JI, Gatad2b, associated with the neurodevelopmental syndrome GAND, plays a critical role in neurodevelopment and cortical patterning. Transl Psychiatry. 2024 Jan 18;14(1):33 |
1 | J:333560 Ahmed NY, Knowles R, Liu L, Yan Y, Li X, Schumann U, Wang Y, Sontani Y, Reynolds N, Natoli R, Wen J, Del Pino I, Mi D, Dehorter N, Developmental deficits of MGE-derived interneurons in the Cntnap2 knockout mouse model of autism spectrum disorder. Front Cell Dev Biol. 2023;11:1112062 |
1 | J:315767 Ahn SY, Kim Y, Kim ST, Swat W, Miner JH, Scaffolding proteins DLG1 and CASK cooperate to maintain the nephron progenitor population during kidney development. J Am Soc Nephrol. 2013 Jun;24(7):1127-38 |
1 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
1 | J:227638 Alvarez S, Diaz M, Flach J, Rodriguez-Acebes S, Lopez-Contreras AJ, Martinez D, Canamero M, Fernandez-Capetillo O, Isern J, Passegue E, Mendez J, Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality. Nat Commun. 2015;6:8548 |
1 | J:291525 Amelio I, Panatta E, Niklison-Chirou MV, Steinert JR, Agostini M, Morone N, Knight RA, Melino G, The C terminus of p73 is essential for hippocampal development. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15694-15701 |
1 | J:170088 Angus-Hill ML, Elbert KM, Hidalgo J, Capecchi MR, T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4914-9 |
1 | J:284333 Arai HN, Sato F, Yamamoto T, Woltjen K, Kiyonari H, Yoshimoto Y, Shukunami C, Akiyama H, Kist R, Sehara-Fujisawa A, Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate. Cell Rep. 2019 Oct 15;29(3):603-616.e5 |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
1 | J:299451 Atkins A, Xu MJ, Li M, Rogers NP, Pryzhkova MV, Jordan PW, SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. Elife. 2020 Nov 17;9:e61171 |
1 | J:336863 Barry-Carroll L, Greulich P, Marshall AR, Riecken K, Fehse B, Askew KE, Li K, Garaschuk O, Menassa DA, Gomez-Nicola D, Microglia colonize the developing brain by clonal expansion of highly proliferative progenitors, following allometric scaling. Cell Rep. 2023 May 30;42(5):112425 |
1* | J:181601 Bassett EA, Korol A, Deschamps PA, Buettner R, Wallace VA, Williams T, West-Mays JA, Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29 |
1 | J:176604 Bell SM, Zhang L, Mendell A, Xu Y, Haitchi HM, Lessard JL, Whitsett JA, Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. Dev Biol. 2011 Oct 1;358(1):79-90 |
1 | J:155396 Bellon E, Luyten FP, Tylzanowski P, delta-EF1 is a negative regulator of Ihh in the developing growth plate. J Cell Biol. 2009 Nov 30;187(5):685-99 |
1 | J:229394 Bernier-Latmani J, Cisarovsky C, Demir CS, Bruand M, Jaquet M, Davanture S, Ragusa S, Siegert S, Dormond O, Benedito R, Radtke F, Luther SA, Petrova TV, DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport. J Clin Invest. 2015 Dec;125(12):4572-86 |
1 | J:305458 Bertacchi M, Romano AL, Loubat A, Tran Mau-Them F, Willems M, Faivre L, Khau van Kien P, Perrin L, Devillard F, Sorlin A, Kuentz P, Philippe C, Garde A, Neri F, Di Giaimo R, Oliviero S, Cappello S, D'Incerti L, Frassoni C, Studer M, NR2F1 regulates regional progenitor dynamics in the mouse neocortex and cortical gyrification in BBSOAS patients. EMBO J. 2020 Jul 1;39(13):e104163 |
1 | J:203970 Betancourt J, Katzman S, Chen B, Nuclear factor one B regulates neural stem cell differentiation and axonal projection of corticofugal neurons. J Comp Neurol. 2014 Jan 1;522(1):6-35 |
1* | J:237308 Biosse Duplan M, Komla-Ebri D, Heuze Y, Estibals V, Gaudas E, Kaci N, Benoist-Lasselin C, Zerah M, Kramer I, Kneissel M, Porta DG, Di Rocco F, Legeai-Mallet L, Meckel's and condylar cartilages anomalies in achondroplasia result in defective development and growth of the mandible. Hum Mol Genet. 2016 Jul 15;25(14):2997-3010 |
1* | J:84903 Bolcato-Bellemin AL, Lefebvre O, Arnold C, Sorokin L, Miner JH, Kedinger M, Simon-Assmann P, Laminin alpha5 chain is required for intestinal smooth muscle development. Dev Biol. 2003 Aug 15;260(2):376-90 |
1 | J:353339 Butts JC, Wu SR, Durham MA, Dhindsa RS, Revelli JP, Ljungberg MC, Saulnier O, McLaren ME, Taylor MD, Zoghbi HY, A single-cell transcriptomic map of the developing Atoh1 lineage identifies neural fate decisions and neuronal diversity in the hindbrain. Dev Cell. 2024 Aug 19;59(16):2171-2188.e7 |
1 | J:239074 Cai H, Liu A, Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling. Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14751-14756 |
1 | J:236889 Cao D, Ma X, Cai J, Luan J, Liu AJ, Yang R, Cao Y, Zhu X, Zhang H, Chen YX, Shi Y, Shi GX, Zou D, Cao X, Grusby MJ, Xie Z, Zhang WJ, ZBTB20 is required for anterior pituitary development and lactotrope specification. Nat Commun. 2016 Apr 15;7:11121 |
1 | J:228026 Capecchi MR, Pozner A, ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination. Nat Commun. 2015;6:8763 |
1 | J:177402 Carpentier R, Suner RE, van Hul N, Kopp JL, Beaudry JB, Cordi S, Antoniou A, Raynaud P, Lepreux S, Jacquemin P, Leclercq IA, Sander M, Lemaigre FP, Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells. Gastroenterology. 2011 Oct;141(4):1432-1438.e4 |
1 | J:335626 Castillo V, Diaz-Astudillo P, Corrales-Orovio R, San Martin S, Egana JT, Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin. Cells. 2023 Apr 22;12(9) |
1 | J:160586 Chen CM, Wang HY, You LR, Shang RL, Liu FC, Expression analysis of an evolutionary conserved metallophosphodiesterase gene, Mpped1, in the normal and beta-catenin-deficient malformed dorsal telencephalon. Dev Dyn. 2010 Jun;239(6):1797-806 |
1 | J:316527 Chen HH, Welling M, Bloch DB, Munoz J, Mientjes E, Chen X, Tramp C, Wu J, Yabuuchi A, Chou YF, Buecker C, Krainer A, Willemsen R, Heck AJ, Geijsen N, DAZL limits pluripotency, differentiation, and apoptosis in developing primordial germ cells. Stem Cell Reports. 2014 Nov 11;3(5):892-904 |
1 | J:185237 Chen L, Ma Y, Kim EY, Yu W, Schwartz RJ, Qian L, Wang J, Conditional ablation of Ezh2 in murine hearts reveals its essential roles in endocardial cushion formation, cardiomyocyte proliferation and survival. PLoS One. 2012;7(2):e31005 |
1* | J:143541 Chen L, Melendez J, Campbell K, Kuan CY, Zheng Y, Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly. Dev Biol. 2009 Jan 1;325(1):162-70 |
1 | J:286635 Chen SY, Lu KM, Ko HA, Huang TH, Hao JH, Yan YT, Chang SL, Evans SM, Liu FC, Parcellation of the striatal complex into dorsal and ventral districts. Proc Natl Acad Sci U S A. 2020 Mar 31;117(13):7418-7429 |
1 | J:309486 Chen X, Qin L, Liu Z, Liao L, Martin JF, Xu J, Knockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy Phenotype. Int J Biol Sci. 2015;11(9):1056-72 |
1 | J:346633 Cheng J, Wang Z, Tang M, Zhang W, Li G, Tan S, Mu C, Hu M, Zhang D, Jia X, Wen Y, Guo H, Xu D, Liu L, Li J, Xia K, Li F, Duan R, Xu Z, Yuan L, KCTD10 regulates brain development by destabilizing brain disorder-associated protein KCTD13. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2315707121 |
1 | J:299855 Cheng YY, Chou YT, Lai FJ, Jan MS, Chang TH, Jou IM, Chen PS, Lo JY, Huang SS, Chang NS, Liou YT, Hsu PC, Cheng HC, Lin YS, Hsu LJ, Wwox deficiency leads to neurodevelopmental and degenerative neuropathies and glycogen synthase kinase 3beta-mediated epileptic seizure activity in mice. Acta Neuropathol Commun. 2020 Jan 30;8(1):6 |
1 | J:227188 Choe Y, Huynh T, Pleasure SJ, Epithelial cells supply Sonic Hedgehog to the perinatal dentate gyrus via transport by platelets. Elife. 2015;4 |
1 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1 | J:102162 Cicero S, Herrup K, Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci. 2005 Oct 19;25(42):9658-68 |
1 | J:158610 Coffinier C, Chang SY, Nobumori C, Tu Y, Farber EA, Toth JI, Fong LG, Young SG, Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5076-81 |
1 | J:179734 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS, Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Dev Dyn. 2012 Feb;241(2):303-14 |
1* | J:144178 Couillard M, Trudel M, C-myc as a modulator of renal stem/progenitor cell population. Dev Dyn. 2009 Feb;238(2):405-14 |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
1* | J:121517 Danielian PS, Bender Kim CF, Caron AM, Vasile E, Bronson RT, Lees JA, E2f4 is required for normal development of the airway epithelium. Dev Biol. 2007 May 15;305(2):564-76 |
1 | J:177724 Danussi C, Petrucco A, Wassermann B, Pivetta E, Modica TM, Belluz Ldel B, Colombatti A, Spessotto P, EMILIN1-alpha4/alpha9 integrin interaction inhibits dermal fibroblast and keratinocyte proliferation. J Cell Biol. 2011 Oct 3;195(1):131-45 |
1* | J:359964 DeSpenza T Jr, Singh A, Allington G, Zhao S, Lee J, Kiziltug E, Prina ML, Desmet N, Dang HQ, Fields J, Nelson-Williams C, Zhang J, Mekbib KY, Dennis E, Mehta NH, Duy PQ, Shimelis H, Walsh LK, Marlier A, Deniz E, Lake EMR, Constable RT, Hoffman EJ, Lifton RP, Gulledge A, Fiering S, Moreno-De-Luca A, Haider S, Alper SL, Jin SC, Kahle KT, Luikart BW, Pathogenic variants in autism gene KATNAL2 cause hydrocephalus and disrupt neuronal connectivity by impairing ciliary microtubule dynamics. Proc Natl Acad Sci U S A. 2024 Jul 2;121(27):e2314702121 |
1 | J:358649 Dias AP, Rehmani T, Applin BD, Salih M, Tuana B, SLMAP3 is crucial for organogenesis through mechanisms involving primary cilia formation. Open Biol. 2024 Oct;14(10):rsob240206 |
1 | J:119851 DiPersio CM, van der Neut R, Georges-Labouesse E, Kreidberg JA, Sonnenberg A, Hynes RO, alpha3beta1 and alpha6beta4 integrin receptors for laminin-5 are not essential for epidermal morphogenesis and homeostasis during skin development. J Cell Sci. 2000 Sep;113(Pt 17):3051-62 |
1 | J:207252 Drosten M, Lechuga CG, Barbacid M, Ras signaling is essential for skin development. Oncogene. 2014 May 29;33(22):2857-65 |
1* | J:305426 Du G, Oatley MJ, Law NC, Robbins C, Wu X, Oatley JM, Proper timing of a quiescence period in precursor prospermatogonia is required for stem cell pool establishment in the male germline. Development. 2021 May 1;148(9):dev194571 |
1 | J:237001 Duan X, Bradbury SR, Olsen BR, Berendsen AD, VEGF stimulates intramembranous bone formation during craniofacial skeletal development. Matrix Biol. 2016 May-Jul;52-54:127-40 |
1 | J:260456 Duteil D, Tourrette Y, Eberlin A, Willmann D, Patel D, Friedrichs N, Muller JM, Schule R, The histone acetyltransferase inhibitor Nir regulates epidermis development. Development. 2018 Mar 21;145(6):dev158543 |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
1 | J:87395 Eberl G, Marmon S, Sunshine MJ, Rennert PD, Choi Y, Littman DR, An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat Immunol. 2004 Jan;5(1):64-73 |
1 | J:206141 Eguren M, Porlan E, Manchado E, Garcia-Higuera I, Canamero M, Farinas I, Malumbres M, The APC/C cofactor Cdh1 prevents replicative stress and p53-dependent cell death in neural progenitors. Nat Commun. 2013;4:2880 |
1 | J:327958 Eliason S, Su D, Pinho F, Sun Z, Zhang Z, Li X, Sweat M, Venugopalan SR, He B, Bustin M, Amendt BA, HMGN2 represses gene transcription via interaction with transcription factors Lef-1 and Pitx2 during amelogenesis. J Biol Chem. 2022 Jul 21;298(9):102295 |
1 | J:194118 Fantauzzo KA, Kurban M, Levy B, Christiano AM, Trps1 and its target gene Sox9 regulate epithelial proliferation in the developing hair follicle and are associated with hypertrichosis. PLoS Genet. 2012;8(11):e1003002 |
1 | J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489 |
1 | J:303325 Fehrenbach MK, Tjwa M, Bechmann I, Krueger M, Decreased microglial numbers in Vav1-Cre(+):dicer knock-out mice suggest a second source of microglia beyond yolk sac macrophages. Ann Anat. 2018 Jul;218:190-198 |
1 | J:361578 Feng W, Hong N, Wu Y, Huang J, Zhang Q, Liu G, Qian Z, Chen Y, Jin L, Ding X, Zhao P, Chen AF, Yu Y, Deficiency of Sox7 leads to congenital aortic stenosis via abnormal valve remodeling. J Mol Cell Cardiol. 2025 Feb;199:81-94 |
1 | J:134976 Galichet C, Guillemot F, Parras CM, Neurogenin 2 has an essential role in development of the dentate gyrus. Development. 2008 Jun;135(11):2031-41 |
1 | J:324468 Gan P, Wang Z, Morales MG, Zhang Y, Bassel-Duby R, Liu N, Olson EN, RBPMS is an RNA-binding protein that mediates cardiomyocyte binucleation and cardiovascular development. Dev Cell. 2022 Apr 25;57(8):959-973.e7 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:307319 George NM, Boerner BP, Mir SU, Guinn Z, Sarvetnick NE, Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass. Mol Endocrinol. 2015 Nov;29(11):1594-607 |
1 | J:217584 Gerstmann K, Pensold D, Symmank J, Khundadze M, Hubner CA, Bolz J, Zimmer G, Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions. Development. 2015 Jan 1;142(1):140-50 |
1 | J:167212 Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ, Subtypes of medulloblastoma have distinct developmental origins. Nature. 2010 Dec 23;468(7327):1095-9 |
1 | J:215584 Gil-Sanz C, Landeira B, Ramos C, Costa MR, Muller U, Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon. J Neurosci. 2014 Aug 6;34(32):10475-87 |
1* | J:283039 Giralt A, Brito V, Pardo M, Rubio SE, Marion-Poll L, Martin-Ibanez R, Zamora-Moratalla A, Bosch C, Ballesteros JJ, Blasco E, Garcia-Torralba A, Pascual M, Pumarola M, Alberch J, Gines S, Martin ED, Segovia J, Soriano E, Canals JM, Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation. Exp Neurol. 2020 Jan;323:113095 |
1 | J:151321 Glickstein SB, Monaghan JA, Koeller HB, Jones TK, Ross ME, Cyclin D2 is critical for intermediate progenitor cell proliferation in the embryonic cortex. J Neurosci. 2009 Jul 29;29(30):9614-24 |
1* | J:123724 Golonzhka O, Leid M, Indra G, Indra AK, Expression of COUP-TF-interacting protein 2 (CTIP2) in mouse skin during development and in adulthood. Gene Expr Patterns. 2007 Aug;7(7):754-60 |
2 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
1* | J:191140 Grigoryan M, Kedees MH, Guz Y, Teitelman G, Phenotype of entero-endocrine L cells becomes restricted during development. Dev Dyn. 2012 Dec;241(12):1986-92 |
1 | J:237540 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R, The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development. 2016 Nov 15;143(22):4182-4192 |
1 | J:283354 Guiu J, Hannezo E, Yui S, Demharter S, Ulyanchenko S, Maimets M, Jorgensen A, Perlman S, Lundvall L, Mamsen LS, Larsen A, Olesen RH, Andersen CY, Thuesen LL, Hare KJ, Pers TH, Khodosevich K, Simons BD, Jensen KB, Tracing the origin of adult intestinal stem cells. Nature. 2019 Jun;570(7759):107-111 |
1 | J:342170 Gura MA, Bartholomew MA, Abt KM, Relovska S, Seymour KA, Freiman RN, Transcription and chromatin regulation by TAF4b during cellular quiescence of developing prospermatogonia. Front Cell Dev Biol. 2023;11:1270408 |
1 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
1 | J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90 |
1* | J:231833 Hashimoto R, Hori K, Owa T, Miyashita S, Dewa K, Masuyama N, Sakai K, Hayase Y, Seto Y, Inoue YU, Inoue T, Ichinohe N, Kawaguchi Y, Akiyama H, Koizumi S, Hoshino M, Origins of oligodendrocytes in the cerebellum, whose development is controlled by the transcription factor, Sox9. Mech Dev. 2016 May;140:25-40 |
1 | J:241998 Haston S, Pozzi S, Carreno G, Manshaei S, Panousopoulos L, Gonzalez-Meljem JM, Apps JR, Virasami A, Thavaraj S, Gutteridge A, Forshew T, Marais R, Brandner S, Jacques TS, Andoniadou CL, Martinez-Barbera JP, MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma. Development. 2017 Jun 15;144(12):2141-2152 |
1 | J:119018 Haubst N, Georges-Labouesse E, De Arcangelis A, Mayer U, Gotz M, Basement membrane attachment is dispensable for radial glial cell fate and for proliferation, but affects positioning of neuronal subtypes. Development. 2006 Aug;133(16):3245-54 |
1 | J:217375 Heavner WE, Andoniadou CL, Pevny LH, Establishment of the neurogenic boundary of the mouse retina requires cooperation of SOX2 and WNT signaling. Neural Dev. 2014;9:27 |
1 | J:219824 Hendley AM, Provost E, Bailey JM, Wang YJ, Cleveland MH, Blake D, Bittman RW, Roeser JC, Maitra A, Reynolds AB, Leach SD, p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas. Dev Biol. 2015 Mar 1;399(1):41-53 |
1 | J:340417 Hendrikse LD, Haldipur P, Saulnier O, Millman J, Sjoboen AH, Erickson AW, Ong W, Gordon V, Coudiere-Morrison L, Mercier AL, Shokouhian M, Suarez RA, Ly M, Borlase S, Scott DS, Vladoiu MC, Farooq H, Sirbu O, Nakashima T, Nambu S, Funakoshi Y, Bahcheli A, Diaz-Mejia JJ, Golser J, Bach K, Phuong-Bao T, Skowron P, Wang EY, Kumar SA, Balin P, Visvanathan A, Lee JJY, Ayoub R, Chen X, Chen X, Mungall KL, Luu B, Berube P, Wang YC, Pfister SM, Kim SK, Delattre O, Bourdeaut F, Doz F, Masliah-Planchon J, Grajkowska WA, Loukides J, Dirks P, Fevre-Montange M, Jouvet A, French PJ, Kros JM, Zitterbart K, Bailey SD, Eberhart CG, Rao AAN, Giannini C, Olson JM, Garami M, Hauser P, Phillips JJ, Ra YS, de Torres C, Mora J, Li KKW, Ng HK, Poon WS, Pollack IF, Lopez-Aguilar E, Gillespie GY, Van Meter TE, Shofuda T, Vibhakar R, Thompson RC, Cooper MK, Rubin JB, Kumabe T, Jung S, Lach B, Iolascon A, Ferrucci V, de Antonellis P, Zollo M, Cinalli G, Robinson S, Stearns DS, Van Meir EG, Porrati P, Finocchiaro G, Massimino M, Carlotti CG, Faria CC, Roussel MF, Boop F, Chan JA, Aldinger KA, Razavi F, Silvestri E, McLendon RE, Thompson EM, Ansari M, Garre ML, Chico F, Eguia P, Perezpena M, Morrissy AS, Cavalli FMG, Wu X, Daniels C, Rich JN, Jones SJM, Moore RA, Marra MA, Huang X, Reimand J, Sorensen PH, Wechsler-Reya RJ, Weiss WA, Pugh TJ, Garzia L, Kleinman CL, Stein LD, Jabado N, Malkin D, Ayrault O, Golden JA, Ellison DW, Doble B, Ramaswamy V, Werbowetski-Ogilvie TE, Suzuki H, Millen KJ, Taylor MD, Failure of human rhombic lip differentiation underlies medulloblastoma formation. Nature. 2022 Sep;609(7929):1021-1028 |
1 | J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6 |
1 | J:306320 Ho UY, Feng CA, Yeap YY, Bain AL, Wei Z, Shohayeb B, Reichelt ME, Homer H, Khanna KK, Bowles J, Ng DCH, WDR62 is required for centriole duplication in spermatogenesis and manchette removal in spermiogenesis. Commun Biol. 2021 May 31;4(1):645 |
1 | J:166928 Hoeck JD, Jandke A, Blake SM, Nye E, Spencer-Dene B, Brandner S, Behrens A, Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun. Nat Neurosci. 2010 Nov;13(11):1365-72 |
1* | J:220612 Holmes G, van Bakel H, Zhou X, Losic B, Jabs EW, BCL11B expression in intramembranous osteogenesis during murine craniofacial suture development. Gene Expr Patterns. 2015 Jan;17(1):16-25 |
1* | J:239792 Hong KY, Bae H, Park I, Park DY, Kim KH, Kubota Y, Cho ES, Kim H, Adams RH, Yoo OJ, Koh GY, Perilipin+ embryonic preadipocytes actively proliferate along growing vasculatures for adipose expansion. Development. 2015 Aug 01;142(15):2623-32 |
1 | J:175769 Hsu SH, Zhang X, Yu C, Li ZJ, Wunder JS, Hui CC, Alman BA, Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu. Development. 2011 Sep;138(17):3791-801 |
1 | J:173651 Hsu YC, Osinski J, Campbell CE, Litwack ED, Wang D, Liu S, Bachurski CJ, Gronostajski RM, Mesenchymal nuclear factor I B regulates cell proliferation and epithelial differentiation during lung maturation. Dev Biol. 2011 Jun 15;354(2):242-52 |
1 | J:213355 Hu J, Lu J, Lian G, Zhang J, Hecht JL, Sheen VL, Filamin B regulates chondrocyte proliferation and differentiation through Cdk1 signaling. PLoS One. 2014;9(2):e89352 |
1 | J:253242 Hu XL, Chen G, Zhang S, Zheng J, Wu J, Bai QR, Wang Y, Li J, Wang H, Feng H, Li J, Sun X, Xia Q, Yang F, Hang J, Qi C, Phoenix TN, Temple S, Shen Q, Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells. Neuron. 2017 Jul 19;95(2):309-325.e6 |
1 | J:168522 Huang CC, Miyagawa S, Matsumaru D, Parker KL, Yao HH, Progenitor cell expansion and organ size of mouse adrenal is regulated by sonic hedgehog. Endocrinology. 2010 Mar;151(3):1119-28 |
1* | J:163555 Huang CC, Yao HH, Inactivation of Dicer1 in Steroidogenic factor 1-positive cells reveals tissue-specific requirement for Dicer1 in adrenal, testis, and ovary. BMC Dev Biol. 2010;10:66 |
1 | J:332247 Huang XT, Li T, Li T, Xing S, Tian JZ, Ding YF, Cai SL, Yang YS, Wood C, Yang JS, Yang WJ, Embryogenic stem cell-derived intestinal crypt fission directs de novo crypt genesis. Cell Rep. 2022 Dec 13;41(11):111796 |
1 | J:162581 Huillard E, Ziercher L, Blond O, Wong M, Deloulme JC, Souchelnytskyi S, Baudier J, Cochet C, Buchou T, Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalon. Mol Cell Biol. 2010 Jun;30(11):2737-49 |
1 | J:122204 Imai F, Hirai S, Akimoto K, Koyama H, Miyata T, Ogawa M, Noguchi S, Sasaoka T, Noda T, Ohno S, Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex. Development. 2006 May;133(9):1735-44 |
1 | J:188056 Jameson SA, Lin YT, Capel B, Testis development requires the repression of Wnt4 by Fgf signaling. Dev Biol. 2012 Oct 1;370(1):24-32 |
1 | J:333564 Javed A, Santos-Franca PL, Mattar P, Cui A, Kassem F, Cayouette M, Ikaros family proteins redundantly regulate temporal patterning in the developing mouse retina. Development. 2023 Jan 15;150(2):dev200436 |
1 | J:233686 Jia WJ, Jiang S, Tang QL, Shen D, Xue B, Ning W, Li CJ, Geranylgeranyl Diphosphate Synthase Modulates Fetal Lung Branching Morphogenesis Possibly through Controlling K-Ras Prenylation. Am J Pathol. 2016 Jun;186(6):1454-65 |
1 | J:278542 Jia Z, Nie Y, Yue F, Kong Y, Gu L, Gavin TP, Liu X, Kuang S, A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration. Elife. 2019 Aug 8;8:e47097 |
1 | J:273296 Kaiser K, Gyllborg D, Prochazka J, Salasova A, Kompanikova P, Molina FL, Laguna-Goya R, Radaszkiewicz T, Harnos J, Prochazkova M, Potesil D, Barker RA, Casado AG, Zdrahal Z, Sedlacek R, Arenas E, Villaescusa JC, Bryja V, WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis. Nat Commun. 2019 Apr 2;10(1):1498 |
1 | J:235517 Kam JW, Dumontier E, Baim C, Brignall AC, Mendes da Silva D, Cowan M, Kennedy TE, Cloutier JF, RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016 May 1;143(9):1534-46 |
1 | J:249035 Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M, McGillewie L, Bar S, Minocha S, Chevalier C, Po C, Chelly J, Mandel JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, Herault Y, Collins SC, Friant S, Godin JD, Yalcin B, WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9308-E9317 |
1 | J:94393 Karreth F, Hoebertz A, Scheuch H, Eferl R, Wagner EF, The AP1 transcription factor Fra2 is required for efficient cartilage development. Development. 2004 Nov;131(22):5717-25 |
1 | J:198772 Katayama K, Imai F, Campbell K, Lang RA, Zheng Y, Yoshida Y, RhoA and Cdc42 are required in pre-migratory progenitors of the medial ganglionic eminence ventricular zone for proper cortical interneuron migration. Development. 2013 Aug;140(15):3139-45 |
1 | J:327969 Khattar D, Fernandes S, Snowball J, Guo M, Gillen MC, Jain SS, Sinner D, Zacharias W, Swarr DT, PI3K signaling specifies proximal-distal fate by driving a developmental gene regulatory network in SOX9+ mouse lung progenitors. Elife. 2022 Aug 17;11:e67954 |
1* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
1 | J:263685 Kitami K, Kitami M, Kaku M, Wang B, Komatsu Y, BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development. PLoS Genet. 2018 May;14(5):e1007340 |
1* | J:153218 Klinger S, Turgeon B, Levesque K, Wood GA, Aagaard-Tillery KM, Meloche S, Loss of Erk3 function in mice leads to intrauterine growth restriction, pulmonary immaturity, and neonatal lethality. Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16710-5 |
1 | J:222255 Knock E, Pereira J, Lombard PD, Dimond A, Leaford D, Livesey FJ, Hendrich B, The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex. Neural Dev. 2015;10:13 |
1 | J:48968 Korinek V, Barker N, Moerer P, van Donselaar E, Huls G, Peters PJ, Clevers H, Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat Genet. 1998 Aug;19(4):379-83 |
1 | J:353381 Kostic L, Leung C, Ahmad Murad K, Kancheva S, Perna S, Lee B, Barker N, Lgr5 marks stem/progenitor cells contributing to epithelial and muscle development in the mouse esophagus. Nat Commun. 2024 Aug 21;15(1):7145 |
1 | J:156489 Krentz AD, Murphy MW, Kim S, Cook MS, Capel B, Zhu R, Matin A, Sarver AL, Parker KL, Griswold MD, Looijenga LH, Bardwell VJ, Zarkower D, The DM domain protein DMRT1 is a dose-sensitive regulator of fetal germ cell proliferation and pluripotency. Proc Natl Acad Sci U S A. 2009 Dec 29;106(52):22323-8 |
1 | J:195630 Krolewski RC, Packard A, Jang W, Wildner H, Schwob JE, Ascl1 (Mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium. PLoS One. 2012;7(12):e51737 |
1 | J:321428 Kruber P, Angay O, Winkler A, Bosl MR, Kneitz S, Heinze KG, Gessler M, Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation. Int J Cancer. 2019 Mar 15;144(6):1391-1400 |
1 | J:240472 Kumar N, Srivillibhuthur M, Joshi S, Walton KD, Zhou A, Faller WJ, Perekatt AO, Sansom OJ, Gumucio DL, Xing J, Bonder EM, Gao N, White E, Verzi MP, A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis. Development. 2016 Oct 15;143(20):3711-3722 |
1 | J:261926 Kwon E, Todorova K, Wang J, Horos R, Lee KK, Neel VA, Negri GL, Sorensen PH, Lee SW, Hentze MW, Mandinova A, The RNA-binding protein YBX1 regulates epidermal progenitors at a posttranscriptional level. Nat Commun. 2018 Apr 30;9(1):1734 |
1* | J:309394 Kwon HJ, Li L, Jung HS, Hippo pathway/Yap regulates primary enamel knot and dental cusp patterning in tooth morphogenesis. Cell Tissue Res. 2015 Nov;362(2):447-51 |
1* | J:215602 Lai YJ, Li MY, Yang CY, Huang KH, Tsai JC, Wang TW, TRIP6 regulates neural stem cell maintenance in the postnatal mammalian subventricular zone. Dev Dyn. 2014 Sep;243(9):1130-42 |
1 | J:329268 Langouet M, Jolicoeur C, Javed A, Mattar P, Gearhart MD, Daiger SP, Bertelsen M, Tranebjaerg L, Rendtorff ND, Gronskov K, Jespersgaard C, Chen R, Sun Z, Li H, Alirezaie N, Majewski J, Bardwell VJ, Sui R, Koenekoop RK, Cayouette M, Mutations in BCOR, a co-repressor of CRX/OTX2, are associated with early-onset retinal degeneration. Sci Adv. 2022 Sep 9;8(36):eabh2868 |
1 | J:332513 Laporte E, De Vriendt S, Hoekx J, Vankelecom H, Interleukin-6 is dispensable in pituitary normal development and homeostasis but needed for pituitary stem cell activation following local injury. Front Endocrinol (Lausanne). 2022;13:1092063 |
1 | J:317151 Lavado A, Gangwar R, Pare J, Wan S, Fan Y, Cao X, YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development. Dev Biol. 2021 Dec;480:39-49 |
1* | J:199301 Lavado A, He Y, Pare J, Neale G, Olson EN, Giovannini M, Cao X, Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34 |
1 | J:166777 Lavado A, Lagutin OV, Chow LM, Baker SJ, Oliver G, Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. PLoS Biol. 2010;8(8) |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
1 | J:277726 Lecland N, Hsu CY, Chemin C, Merdes A, Bierkamp C, Epidermal development requires ninein for spindle orientation and cortical microtubule organization. Life Sci Alliance. 2019 Apr;2(2) |
1* | J:306217 Lee H, Ko HW, Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development. BMB Rep. 2020 Jul;53(7):367-372 |
1* | J:224807 Lee HY, Angelastro JM, Kenney AM, Mason CA, Greene LA, Reciprocal actions of ATF5 and Shh in proliferation of cerebellar granule neuron progenitor cells. Dev Neurobiol. 2012 Jun;72(6):789-804 |
1 | J:134270 Lee JH, Kim TS, Yang TH, Koo BK, Oh SP, Lee KP, Oh HJ, Lee SH, Kong YY, Kim JM, Lim DS, A crucial role of WW45 in developing epithelial tissues in the mouse. EMBO J. 2008 Apr 23;27(8):1231-42 |
1* | J:293624 Lee S, Sears MJ, Zhang Z, Li H, Salhab I, Krebs P, Xing Y, Nah HD, Williams T, Carstens RP, Cleft lip and cleft palate in Esrp1 knockout mice is associated with alterations in epithelial-mesenchymal crosstalk. Development. 2020 Apr 30;147(21):dev187369 |
1 | J:154048 Li H, MacLean G, Cameron D, Clagett-Dame M, Petkovich M, Cyp26b1 expression in murine Sertoli cells is required to maintain male germ cells in an undifferentiated state during embryogenesis. PLoS One. 2009;4(10):e7501 |
1 | J:205567 Li K, Leung AW, Guo Q, Yang W, Li JY, Shp2-Dependent ERK Signaling Is Essential for Induction of Bergmann Glia and Foliation of the Cerebellum. J Neurosci. 2014 Jan 15;34(3):922-31 |
1 | J:306873 Li L, Jin J, Yang XJ, Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells. iScience. 2019 Oct 25;20:148-167 |
1 | J:294283 Liang Q, Zheng Q, Zuo Y, Chen Y, Ma J, Ni P, Cheng J, SENP2 Suppresses Necdin Expression to Promote Brown Adipocyte Differentiation. Cell Rep. 2019 Aug 20;28(8):2004-2011.e4 |
1 | J:163484 Lin MH, Chang KW, Lin SC, Miner JH, Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling. Dev Biol. 2010 Aug 15;344(2):707-19 |
1 | J:302366 Lin S, Liu W, Chen CL, Sun D, Hu JX, Li L, Ye J, Mei L, Xiong WC, Neogenin-loss in neural crest cells results in persistent hyperplastic primary vitreous formation. J Mol Cell Biol. 2020 Jan 22;12(1):17-31 |
1 | J:352165 Lin Y, Tang W, Huang P, Wang Z, Duan L, Jia C, Sun R, Liu L, Shen J, Denticleless E3 ubiquitin protein ligase (DTL) maintains the proliferation and differentiation of epidermis and hair follicles during skin development. Dev Dyn. 2024 Jul;253(7):635-647 |
1 | J:198157 Liu C, Lin C, Whitaker DT, Bakeri H, Bulgakov OV, Liu P, Lei J, Dong L, Li T, Swaroop A, Prickle1 is expressed in distinct cell populations of the central nervous system and contributes to neuronal morphogenesis. Hum Mol Genet. 2013 Jun 1;22(11):2234-46 |
1 | J:179217 Liu HX, Grosse AS, Iwatsuki K, Mishina Y, Gumucio DL, Mistretta CM, Separate and distinctive roles for Wnt5a in tongue, lingual tissue and taste papilla development. Dev Biol. 2012 Jan 1;361(1):39-56 |
1 | J:272578 Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G, Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. Dev Cell. 2019 Jan 7;48(1):49-63.e7 |
1 | J:302828 Liu R, Yang Y, Shen J, Chen H, Zhang Q, Ba R, Wei Y, Li KC, Zhang X, Zhao C, Fstl1 is involved in the regulation of radial glial scaffold development. Mol Brain. 2015 Sep 17;8:53 |
1 | J:334752 Liu W, Xie H, Liu X, Xu S, Cheng S, Wang Z, Xie T, Zhang ZC, Han J, PQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation. Cell Rep. 2023 Mar 28;42(3):112277 |
1 | J:242757 Liu X, Yagi H, Saeed S, Bais AS, Gabriel GC, Chen Z, Peterson KA, Li Y, Schwartz MC, Reynolds WT, Saydmohammed M, Gibbs B, Wu Y, Devine W, Chatterjee B, Klena NT, Kostka D, de Mesy Bentley KL, Ganapathiraju MK, Dexheimer P, Leatherbury L, Khalifa O, Bhagat A, Zahid M, Pu W, Watkins S, Grossfeld P, Murray SA, Porter GA Jr, Tsang M, Martin LJ, Benson DW, Aronow BJ, Lo CW, The complex genetics of hypoplastic left heart syndrome. Nat Genet. 2017 Jul;49(7):1152-1159 |
1 | J:160533 Lizarraga SB, Margossian SP, Harris MH, Campagna DR, Han AP, Blevins S, Mudbhary R, Barker JE, Walsh CA, Fleming MD, Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors. Development. 2010 Jun;137(11):1907-17 |
1 | J:182013 Lopes R, Verhey van Wijk N, Neves G, Pachnis V, Transcription factor LIM homeobox 7 (Lhx7) maintains subtype identity of cholinergic interneurons in the mammalian striatum. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):3119-24 |
1 | J:217690 Lopez-Arribillaga E, Rodilla V, Pellegrinet L, Guiu J, Iglesias M, Roman AC, Gutarra S, Gonzalez S, Munoz-Canoves P, Fernandez-Salguero P, Radtke F, Bigas A, Espinosa L, Bmi1 regulates murine intestinal stem cell proliferation and self-renewal downstream of Notch. Development. 2015 Jan 1;142(1):41-50 |
1* | J:175083 Lorenz A, Deutschmann M, Ahlfeld J, Prix C, Koch A, Smits R, Fodde R, Kretzschmar HA, Schuller U, Severe alterations of cerebellar cortical development after constitutive activation of wnt signaling in granule neuron precursors. Mol Cell Biol. 2011 Aug;31(16):3326-38 |
1 | J:315454 Loscertales M, Nicolaou F, Jeanne M, Longoni M, Gould DB, Sun Y, Maalouf FI, Nagy N, Donahoe PK, Type IV collagen drives alveolar epithelial-endothelial association and the morphogenetic movements of septation. BMC Biol. 2016 Jul 13;14:59 |
1 | J:333798 Luo S, Liu Z, Bian Q, Wang X, Ectomesenchymal Six1 controls mandibular skeleton formation. Front Genet. 2023;14:1082911 |
1 | J:276746 Lutze G, Haarmann A, Demanou Toukam JA, Buttler K, Wilting J, Becker J, Non-canonical WNT-signaling controls differentiation of lymphatics and extension lymphangiogenesis via RAC and JNK signaling. Sci Rep. 2019 Mar 18;9(1):4739 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1* | J:333071 Ma H, Su L, Xia W, Wang W, Tan G, Jiao J, MacroH2A1.2 deficiency leads to neural stem cell differentiation defects and autism-like behaviors. EMBO Rep. 2021 Jul 5;22(7):e52150 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
1 | J:177840 Magri L, Cambiaghi M, Cominelli M, Alfaro-Cervello C, Cursi M, Pala M, Bulfone A, Garcia-Verdugo JM, Leocani L, Minicucci F, Poliani PL, Galli R, Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions. Cell Stem Cell. 2011 Nov 4;9(5):447-62 |
1 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
1 | J:255932 Mario Gonzalez-Meljem J, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Neda Mousavy-Gharavy S, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Pedro Martinez-Barbera J, Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. Nat Commun. 2017 Nov 28;8(1):1819 |
1 | J:240536 Martin-Ibanez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Garcia-Diaz Barriga G, Edel MJ, Vicario-Abejon C, Alberch J, Girault JA, Chan S, Kastner P, Canals JM, Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017 Apr 15;144(8):1566-1577 |
1 | J:330324 Masuda T, Amann L, Monaco G, Sankowski R, Staszewski O, Krueger M, Del Gaudio F, He L, Paterson N, Nent E, Fernandez-Klett F, Yamasaki A, Frosch M, Fliegauf M, Bosch LFP, Ulupinar H, Hagemeyer N, Schreiner D, Dorrier C, Tsuda M, Grothe C, Joutel A, Daneman R, Betsholtz C, Lendahl U, Knobeloch KP, Lammermann T, Priller J, Kierdorf K, Prinz M, Specification of CNS macrophage subsets occurs postnatally in defined niches. Nature. 2022 Apr;604(7907):740-748 |
1 | J:219894 Mattar P, Ericson J, Blackshaw S, Cayouette M, A conserved regulatory logic controls temporal identity in mouse neural progenitors. Neuron. 2015 Feb 4;85(3):497-504 |
1 | J:252094 Matuzelski E, Bunt J, Harkins D, Lim JWC, Gronostajski RM, Richards LJ, Harris L, Piper M, Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord. Dev Biol. 2017 Dec 15;432(2):286-297 |
1 | J:302193 McDonough A, Elsen GE, Daza RM, Bachleda AR, Pizzo D, DelleTorri OM, Hevner RF, Unipolar (Dendritic) Brush Cells Are Morphologically Complex and Require Tbr2 for Differentiation and Migration. Front Neurosci. 2020;14:598548 |
1 | J:175603 Mejetta S, Morey L, Pascual G, Kuebler B, Mysliwiec MR, Lee Y, Shiekhattar R, Di Croce L, Benitah SA, Jarid2 regulates mouse epidermal stem cell activation and differentiation. EMBO J. 2011;30(17):3635-46 |
2* | J:182715 Monahan P, Himes AD, Parfieniuk A, Raetzman LT, p21, an important mediator of quiescence during pituitary tumor formation, is dispensable for normal pituitary development during embryogenesis. Mech Dev. 2012 Jan-Feb;128(11-12):640-52 |
1 | J:331478 Monko T, Rebertus J, Stolley J, Salton SR, Nakagawa Y, Thalamocortical axons regulate neurogenesis and laminar fates in the early sensory cortex. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2201355119 |
1 | J:160474 Moreno SG, Attali M, Allemand I, Messiaen S, Fouchet P, Coffigny H, Romeo PH, Habert R, TGFbeta signaling in male germ cells regulates gonocyte quiescence and fertility in mice. Dev Biol. 2010 Jun 1;342(1):74-84 |
1 | J:324116 Morita R, Sanzen N, Sasaki H, Hayashi T, Umeda M, Yoshimura M, Yamamoto T, Shibata T, Abe T, Kiyonari H, Furuta Y, Nikaido I, Fujiwara H, Tracing the origin of hair follicle stem cells. Nature. 2021 Jun;594(7864):547-552 |
1* | J:132157 Nakamura T, de Vega S, Fukumoto S, Jimenez L, Unda F, Yamada Y, Transcription factor epiprofin is essential for tooth morphogenesis by regulating epithelial cell fate and tooth number. J Biol Chem. 2008 Feb 22;283(8):4825-33 |
1 | J:330740 Narayanan R, Pham L, Kerimoglu C, Watanabe T, Castro Hernandez R, Sokpor G, Ulmke PA, Kiszka KA, Tonchev AB, Rosenbusch J, Seong RH, Teichmann U, Frahm J, Fischer A, Bonn S, Stoykova A, Staiger JF, Tuoc T, Chromatin Remodeling BAF155 Subunit Regulates the Genesis of Basal Progenitors in Developing Cortex. iScience. 2018 Jun 29;4:109-126 |
1 | J:353047 Nevorankova P, Sulcova M, Kavkova M, Zimcik D, Balkova SM, Peleskova K, Kristekova D, Jakesova V, Zikmund T, Kaiser J, Hola LI, Kolar M, Buchtova M, Region-specific gene expression profiling of early mouse mandible uncovered SATB2 as a key molecule for teeth patterning. Sci Rep. 2024 Aug 6;14(1):18212 |
1 | J:326253 Ni L, Lin B, Hu L, Zhang R, Fu F, Shen M, Yang J, Shi D, Pyruvate Kinase M2 Protects Heart from Pressure Overload-Induced Heart Failure by Phosphorylating RAC1. J Am Heart Assoc. 2022 Jun 7;11(11):e024854 |
1 | J:272073 Nicola Z, Fabel K, Kempermann G, Development of the adult neurogenic niche in the hippocampus of mice. Front Neuroanat. 2015;9:53 |
1* | J:204460 Nie X, Arend LJ, Pkd1 is required for male reproductive tract development. Mech Dev. 2013 Nov-Dec;130(11-12):567-76 |
1 | J:240892 Nitarska J, Smith JG, Sherlock WT, Hillege MM, Nott A, Barshop WD, Vashisht AA, Wohlschlegel JA, Mitter R, Riccio A, A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development. Cell Rep. 2016 Nov 01;17(6):1683-1698 |
1 | J:232190 Noda K, Kitami M, Kitami K, Kaku M, Komatsu Y, Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development. Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2589-97 |
1 | J:363605 Ortiz A, Ayhan F, Khandelwal N, Outland E, Jankovic M, Harper M, Konopka G, Cell-type-specific roles of FOXP1 in the excitatory neuronal lineage during early neocortical murine development. Cell Rep. 2025 Mar 5;44(3):115384 |
1 | J:171374 Osorio KM, Lilja KC, Tumbar T, Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol. 2011 Apr 4;193(1):235-50 |
1 | J:256929 Otto T, Candido SV, Pilarz MS, Sicinska E, Bronson RT, Bowden M, Lachowicz IA, Mulry K, Fassl A, Han RC, Jecrois ES, Sicinski P, Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10660-10665 |
1 | J:187391 Pacal M, Bremner R, Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Dev Dyn. 2012 Oct;241(10):1525-44 |
1 | J:316097 Pang L, Tian H, Gao X, Wang W, Wang X, Zhang Z, KMT2D deficiency disturbs the proliferation and cell cycle activity of dental epithelial cell line (LS8) partially via Wnt signaling. Biosci Rep. 2021 Nov 26;41(11) |
1 | J:241853 Parisot J, Flore G, Bertacchi M, Studer M, COUP-TFI mitotically regulates production and migration of dentate granule cells and modulates hippocampal Cxcr4 expression. Development. 2017 Jun 01;144(11):2045-2058 |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
1 | J:290493 Peng YR, James RE, Yan W, Kay JN, Kolodkin AL, Sanes JR, Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch. Neuron. 2020 Feb 5;105(3):464-474.e6 |
1 | J:236636 Planas-Paz L, Orsini V, Boulter L, Calabrese D, Pikiolek M, Nigsch F, Xie Y, Roma G, Donovan A, Marti P, Beckmann N, Dill MT, Carbone W, Bergling S, Isken A, Mueller M, Kinzel B, Yang Y, Mao X, Nicholson TB, Zamponi R, Capodieci P, Valdez R, Rivera D, Loew A, Ukomadu C, Terracciano LM, Bouwmeester T, Cong F, Heim MH, Forbes SJ, Ruffner H, Tchorz JS, The RSPO-LGR4/5-ZNRF3/RNF43 module controls liver zonation and size. Nat Cell Biol. 2016 May;18(5):467-79 |
1 | J:301859 Poche RA, Zhang M, Rueda EM, Tong X, McElwee ML, Wong L, Hsu CW, Dejosez M, Burns AR, Fox DA, Martin JF, Zwaka TP, Dickinson ME, RONIN Is an Essential Transcriptional Regulator of Genes Required for Mitochondrial Function in the Developing Retina. Cell Rep. 2016 Feb 23;14(7):1684-1697 |
1* | J:326026 Prokopuk L, Jarred EG, Blucher RO, McLaughlin EA, Stringer JM, Western PS, An essential role for Polycomb Repressive Complex 2 in the mouse ovary. Reproduction. 2022 Feb 17;163(3):167-182 |
1 | J:155110 Puig I, Champeval D, De Santa Barbara P, Jaubert F, Lyonnet S, Larue L, Deletion of Pten in the mouse enteric nervous system induces ganglioneuromatosis and mimics intestinal pseudoobstruction. J Clin Invest. 2009 Dec;119(12):3586-96 |
1 | J:244435 Qin S, Ware SM, Waclaw RR, Campbell K, Septal contributions to olfactory bulb interneuron diversity in the embryonic mouse telencephalon: role of the homeobox gene Gsx2. Neural Dev. 2017 Aug 16;12(1):13 |
1 | J:252201 Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A, p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct;137(10):2157-2167 |
1* | J:73292 Ridanpaa M, Fodde R, Kielman M, Dynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structures. Mech Dev. 2001 Dec;109(2):173-81 |
1 | J:349014 Rinta-Jaskari MM, Naillat F, Ruotsalainen HJ, Ronkainen VP, Heljasvaara R, Akram SU, Izzi V, Miinalainen I, Vainio SJ, Pihlajaniemi TA, Collagen XVIII regulates extracellular matrix integrity in the developing nephrons and impacts nephron progenitor cell behavior. Matrix Biol. 2024 May 22; |
1 | J:187684 Rodriguez M, Choi J, Park S, Sockanathan S, Gde2 regulates cortical neuronal identity by controlling the timing of cortical progenitor differentiation. Development. 2012 Oct;139(20):3870-9 |
1 | J:181275 Romano RA, Smalley K, Magraw C, Serna VA, Kurita T, Raghavan S, Sinha S, DeltaNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation. Development. 2012 Feb;139(4):772-82 |
1 | J:292237 Roostalu U, Aldeiri B, Albertini A, Humphreys N, Simonsen-Jackson M, Wong JKF, Cossu G, Distinct Cellular Mechanisms Underlie Smooth Muscle Turnover in Vascular Development and Repair. Circ Res. 2018 Jan 19;122(2):267-281 |
1 | J:269511 Roy A, Skibo J, Kalume F, Ni J, Rankin S, Lu Y, Dobyns WB, Mills GB, Zhao JJ, Baker SJ, Millen KJ, Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy. Elife. 2015 Dec 3;4:e12703 |
1 | J:266746 Rudkouskaya A, Welch I, Dagnino L, ILK modulates epithelial polarity and matrix formation in hair follicles. Mol Biol Cell. 2014 Mar;25(5):620-32 |
1 | J:205334 Saba R, Kato Y, Saga Y, NANOS2 promotes male germ cell development independent of meiosis suppression. Dev Biol. 2014 Jan 1;385(1):32-40 |
1 | J:316218 Schoof M, Hellwig M, Harrison L, Holdhof D, Lauffer MC, Niesen J, Virdi S, Indenbirken D, Schuller U, The basic helix-loop-helix transcription factor TCF4 impacts brain architecture as well as neuronal morphology and differentiation. Eur J Neurosci. 2020 Jun;51(11):2219-2235 |
1 | J:296487 Schoof M, Launspach M, Holdhof D, Nguyen L, Engel V, Filser S, Peters F, Immenschuh J, Hellwig M, Niesen J, Mall V, Ertl-Wagner B, Hagel C, Spohn M, Lutz B, Sedlacik J, Indenbirken D, Merk DJ, Schuller U, The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration. Acta Neuropathol Commun. 2019 Dec 5;7(1):199 |
1* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
1 | J:99391 Shu W, Guttentag S, Wang Z, Andl T, Ballard P, Lu MM, Piccolo S, Birchmeier W, Whitsett JA, Millar SE, Morrisey EE, Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung. Dev Biol. 2005 Jul 1;283(1):226-39 |
1 | J:298087 Son AI, Mohammad S, Sasaki T, Ishii S, Yamashita S, Hashimoto-Torii K, Torii M, Dual Role of Rbpj in the Maintenance of Neural Progenitor Cells and Neuronal Migration in Cortical Development. Cereb Cortex. 2020 Nov 3;30(12):6444-6457 |
1 | J:350099 Song X, Chen H, Shang Z, Du H, Li Z, Wen Y, Liu G, Qi D, You Y, Yang Z, Zhang Z, Xu Z, Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons. Neurosci Bull. 2021 Jul;37(7):985-998 |
1* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1* | J:244087 Stopp S, Grundl M, Fackler M, Malkmus J, Leone M, Naumann R, Frantz S, Wolf E, von Eyss B, Engel FB, Gaubatz S, Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during development. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):8029-8034 |
1 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
1* | J:324175 Su YC, Hung TH, Wang TF, Lee YH, Wang TW, Yu JY, YAP maintains the production of intermediate progenitor cells and upper-layer projection neurons in the mouse cerebral cortex. Dev Dyn. 2022 May;251(5):846-863 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1 | J:237541 Sun Z, Yu W, Sanz Navarro M, Sweat M, Eliason S, Sharp T, Liu H, Seidel K, Zhang L, Moreno M, Lynch T, Holton NE, Rogers L, Neff T, Goodheart MJ, Michon F, Klein OD, Chai Y, Dupuy A, Engelhardt JF, Chen Z, Amendt BA, Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal. Development. 2016 Nov 15;143(22):4115-4126 |
1* | J:92054 Taglialatela P, Soria JM, Caironi V, Moiana A, Bertuzzi S, Compromised generation of GABAergic interneurons in the brains of Vax1-/- mice. Development. 2004 Sep;131(17):4239-49 |
1 | J:112461 Tang LS, Alger HM, Pereira FA, COUP-TFI controls Notch regulation of hair cell and support cell differentiation. Development. 2006 Sep;133(18):3683-93 |
1 | J:156253 Tateossian H, Hardisty-Hughes RE, Morse S, Romero MR, Hilton H, Dean C, Brown SD, Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant. Pathogenetics. 2009;2(1):5 |
1 | J:306384 Terrey M, Adamson SI, Chuang JH, Ackerman SL, Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology. Elife. 2021 Apr 26;10:e66904 |
1 | J:307817 Theis A, Singer RA, Garofalo D, Paul A, Narayana A, Sussel L, Groucho co-repressor proteins regulate beta cell development and proliferation by repressing Foxa1 in the developing mouse pancreas. Development. 2021 Mar 24;148(6):dev192401 |
1 | J:173842 Tian Y, Lei L, Minden A, A key role for Pak4 in proliferation and differentiation of neural progenitor cells. Dev Biol. 2011 May 15;353(2):206-16 |
1* | J:122819 Tomaszewski J, Joseph A, Archambeault D, Yao HH, Essential roles of inhibin beta A in mouse epididymal coiling. Proc Natl Acad Sci U S A. 2007 Jul 3;104(27):11322-7 |
1 | J:279607 Tonchev AB, Tuoc TC, Rosenthal EH, Studer M, Stoykova A, Zbtb20 modulates the sequential generation of neuronal layers in developing cortex. Mol Brain. 2016 Jun 9;9(1):65 |
1* | J:72724 Toresson H, Campbell K, A role for Gsh1 in the developing striatum and olfactory bulb of Gsh2 mutant mice. Development. 2001 Dec;128(23):4769-80 |
1* | J:64588 Toresson H, Potter SS, Campbell K, Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for pax6 and gsh2. Development. 2000 Oct;127(20):4361-71 |
1 | J:216299 Toyo-oka K, Wachi T, Hunt RF, Baraban SC, Taya S, Ramshaw H, Kaibuchi K, Schwarz QP, Lopez AF, Wynshaw-Boris A, 14-3-3epsilon and zeta regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brain. J Neurosci. 2014 Sep 3;34(36):12168-81 |
1 | J:208719 Tsai MJ, Yang-Yen HF, Chiang MK, Wang MJ, Wu SS, Chen SH, TCTP is essential for beta-cell proliferation and mass expansion during development and beta-cell adaptation in response to insulin resistance. Endocrinology. 2014 Feb;155(2):392-404 |
1 | J:266598 Ustiyan V, Bolte C, Zhang Y, Han L, Xu Y, Yutzey KE, Zorn AM, Kalin TV, Shannon JM, Kalinichenko VV, FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme. Dev Biol. 2018 Nov 1;443(1):50-63 |
1 | J:304564 Venkataramanappa S, Schutz D, Saaber F, Kumar PA, Abe P, Schulz S, Stumm R, The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS Genet. 2021 Mar;17(3):e1009441 |
1 | J:309451 Vinsland E, Baskaran P, Mihaylov SR, Hobbs C, Wood H, Bouybayoune I, Shah K, Houart C, Tee AR, Murn J, Fernandes C, Bateman JM, The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021 Aug 11;11(1):16299 |
1 | J:233479 Vong KI, Leung CK, Behringer RR, Kwan KM, Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum. Mol Brain. 2015;8:25 |
1* | J:337458 Waldhauser V, Baroti T, Frob F, Wegner M, PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12) |
1* | J:316179 Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y, An epigenetic circuit controls neurogenic programs during neocortex development. Development. 2021;148:dev199772 |
1 | J:171423 Wang H, Ge G, Uchida Y, Luu B, Ahn S, Gli3 is required for maintenance and fate specification of cortical progenitors. J Neurosci. 2011 Apr 27;31(17):6440-8 |
1 | J:339243 Wang J, Wang A, Tian K, Hua X, Zhang B, Zheng Y, Kong X, Li W, Xu L, Wang J, Li Z, Liu Y, Zhou Y, A Ctnnb1 enhancer regulates neocortical neurogenesis by controlling the abundance of intermediate progenitors. Cell Discov. 2022 Aug 2;8(1):74 |
1 | J:235720 Wang PS, Chou FS, Ramachandran S, Xia S, Chen HY, Guo F, Suraneni P, Maher BJ, Li R, Crucial roles of the Arp2/3 complex during mammalian corticogenesis. Development. 2016 Aug 1;143(15):2741-52 |
1 | J:236342 Wang W, Jossin Y, Chai G, Lien WH, Tissir F, Goffinet AM, Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun. 2016 Mar 04;7:10936 |
1 | J:101174 Wang Y, Xiao R, Yang F, Karim BO, Iacovelli AJ, Cai J, Lerner CP, Richtsmeier JT, Leszl JM, Hill CA, Yu K, Ornitz DM, Elisseeff J, Huso DL, Jabs EW, Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse. Development. 2005 Aug;132(15):3537-48 |
1 | J:190491 Wang Y, Zhou X, Oberoi K, Phelps R, Couwenhoven R, Sun M, Rezza A, Holmes G, Percival CJ, Friedenthal J, Krejci P, Richtsmeier JT, Huso DL, Rendl M, Jabs EW, p38 Inhibition ameliorates skin and skull abnormalities in Fgfr2 Beare-Stevenson mice. J Clin Invest. 2012 Jun 1;122(6):2153-64 |
1 | J:286995 Wang YQ, Cheng JM, Wen Q, Tang JX, Li J, Chen SR, Liu YX, An exploration of the role of Sertoli cells on fetal testis development using cell ablation strategy. Mol Reprod Dev. 2020 Feb;87(2):223-230 |
1 | J:96246 Ward RD, Raetzman LT, Suh H, Stone BM, Nasonkin IO, Camper SA, Role of PROP1 in pituitary gland growth. Mol Endocrinol. 2005 Mar;19(3):698-710 |
1 | J:305176 Wei Y, Han X, Zhao C, PDK1 regulates the survival of the developing cortical interneurons. Mol Brain. 2020 May 4;13(1):65 |
1 | J:344966 Wei Y, Wang X, Ma Z, Xiang P, Liu G, Yin B, Hou L, Shu P, Liu W, Peng X, Sirt6 regulates the proliferation of neural precursor cells and cortical neurogenesis in mice. iScience. 2024 Feb 16;27(2):108706 |
1* | J:261042 Welcker D, Jain M, Khurshid S, Jokic M, Hohne M, Schmitt A, Frommolt P, Niessen CM, Spiro J, Persigehl T, Wittersheim M, Buttner R, Fanciulli M, Schermer B, Reinhardt HC, Benzing T, Hopker K, AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer. Oncogene. 2018 Mar;37(11):1503-1518 |
1 | J:251156 Wen Q, Wang Y, Tang J, Cheng CY, Liu YX, Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development. PLoS One. 2016;11(12):e0167920 |
1 | J:196290 Wheway G, Abdelhamed Z, Natarajan S, Toomes C, Inglehearn C, Johnson CA, Aberrant Wnt signalling and cellular over-proliferation in a novel mouse model of Meckel-Gruber syndrome. Dev Biol. 2013 May 1;377(1):55-66 |
1 | J:172737 Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RA, Peterson AS, Solloway MJ, Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol. 2011 May 30;193(5):935-51 |
1* | J:281257 Witteveen JS, Willemsen MH, Dombroski TC, van Bakel NH, Nillesen WM, van Hulten JA, Jansen EJ, Verkaik D, Veenstra-Knol HE, van Ravenswaaij-Arts CM, Wassink-Ruiter JS, Vincent M, David A, Le Caignec C, Schieving J, Gilissen C, Foulds N, Rump P, Strom T, Cremer K, Zink AM, Engels H, de Munnik SA, Visser JE, Brunner HG, Martens GJ, Pfundt R, Kleefstra T, Kolk SM, Haploinsufficiency of MeCP2-interacting transcriptional co-repressor SIN3A causes mild intellectual disability by affecting the development of cortical integrity. Nat Genet. 2016 Aug;48(8):877-87 |
1 | J:219929 Xia D, Watanabe H, Wu B, Lee SH, Li Y, Tsvetkov E, Bolshakov VY, Shen J, Kelleher RJ 3rd, Presenilin-1 Knockin Mice Reveal Loss-of-Function Mechanism for Familial Alzheimer's Disease. Neuron. 2015 Mar 4;85(5):967-81 |
1 | J:342339 Xia M, Wu M, Li Y, Liu Y, Jia G, Lou Y, Ma J, Gao Q, Xie M, Chen Y, He Y, Li H, Li W, Varying mechanical forces drive sensory epithelium formation. Sci Adv. 2023 Nov 3;9(44):eadf2664 |
1 | J:338913 Xiang J, Guo J, Zhang S, Wu H, Chen YG, Wang J, Li B, Liu H, A stromal lineage maintains crypt structure and villus homeostasis in the intestinal stem cell niche. BMC Biol. 2023 Aug 8;21(1):169 |
1 | J:342871 Xiang J, Pompetti AJ, Faranda AP, Wang Y, Novo SG, Li DW, Duncan MK, ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment. Cells. 2023 Nov 16;12(22) |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
1* | J:136063 Xu B, Qu X, Gu S, Doughman YQ, Watanabe M, Dunwoodie SL, Yang YC, Cited2 is required for fetal lung maturation. Dev Biol. 2008 May 1;317(1):95-105 |
1 | J:273281 Xu D, Yao M, Wang Y, Yuan L, Hoeck JD, Yu J, Liu L, Yeap YYC, Zhang W, Zhang F, Feng Y, Ma T, Wang Y, Ng DCH, Niu X, Su B, Behrens A, Xu Z, MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis. PLoS Biol. 2018 Dec;16(12):e2006613 |
1 | J:285763 Xu M, Han X, Liu R, Li Y, Qi C, Yang Z, Zhao C, Gao J, PDK1 Deficit Impairs the Development of the Dentate Gyrus in Mice. Cereb Cortex. 2019 Mar 1;29(3):1185-1198 |
1 | J:241249 Xue Y, Raharja A, Sim W, Wong ES, Rahmat SA, Lane DP, The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage. Oncogene. 2017 Apr 06;36(14):2002-2013 |
1 | J:221409 Yang M, Yang SL, Herrlinger S, Liang C, Dzieciatkowska M, Hansen KC, Desai R, Nagy A, Niswander L, Moss EG, Chen JF, Lin28 promotes the proliferative capacity of neural progenitor cells in brain development. Development. 2015 May 1;142(9):1616-27 |
1 | J:141958 Yang SH, Andl T, Grachtchouk V, Wang A, Liu J, Syu LJ, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA, Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta-catenin signaling. Nat Genet. 2008 Sep 1;40(9):1130-5 |
1 | J:339368 Yao F, Huang S, Liu J, Tan C, Xu M, Wang D, Huang M, Zhu Y, Huang X, He S, Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis. Cell Death Dis. 2023 Aug 23;14(8):543 |
1 | J:360708 Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K, Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase. Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2320070121 |
1 | J:182350 Zanucco E, Gotz R, Potapenko T, Carraretto I, Ceteci S, Ceteci F, Seeger W, Savai R, Rapp UR, Expression of B-RAF V600E in type II pneumocytes causes abnormalities in alveolar formation, airspace enlargement and tumor formation in mice. PLoS One. 2011;6(12):e29093 |
1 | J:299730 Zhang L, Jing H, Li H, Chen W, Luo B, Zhang H, Dong Z, Li L, Su H, Xiong WC, Mei L, Neddylation is critical to cortical development by regulating Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26448-26459 |
1 | J:225082 Zhang LJ, Bhattacharya S, Leid M, Ganguli-Indra G, Indra AK, Ctip2 is a dynamic regulator of epidermal proliferation and differentiation by integrating EGFR and Notch signaling. J Cell Sci. 2012 Dec 1;125(Pt 23):5733-44 |
1 | J:163662 Zhang Y, Li S, Yuan L, Tian Y, Weidenfeld J, Yang J, Liu F, Chokas AL, Morrisey EE, Foxp1 coordinates cardiomyocyte proliferation through both cell-autonomous and nonautonomous mechanisms. Genes Dev. 2010 Aug 15;24(16):1746-57 |
1 | J:348286 Zhang Z, Wu Y, Fu J, Yu X, Su Y, Jia S, Cheng H, Shen Y, He X, Ren K, Zheng X, Guan H, Rao F, Zhao L, Proteostatic reactivation of the developmental transcription factor TBX3 drives BRAF/MAPK-mediated tumorigenesis. Nat Commun. 2024 May 15;15(1):4108 |
1 | J:316098 Zhao J, Lu P, Wan C, Huang Y, Cui M, Yang X, Hu Y, Zheng Y, Dong J, Wang M, Zhang S, Liu Z, Bian S, Wang X, Wang R, Ren S, Wang D, Yao Z, Chang G, Tang F, Zhao XY, Cell-fate transition and determination analysis of mouse male germ cells throughout development. Nat Commun. 2021 Nov 25;12(1):6839 |
1* | J:336094 Zheng H, Zhang X, Fu J, Xue Y, Chen Z, Yang G, Chen Y, Chen D, Yuan G, CHIP inhibits odontoblast differentiation through promoting DLX3 polyubiquitylation and degradation. Development. 2023 May 15;150(10):dev200848 |
Mkx mohawk homeobox (Synonyms: 9430023B20Rik, Irxl1) | |
Results | Reference |
1 | J:311884 Berthet E, Chen C, Butcher K, Schneider RA, Alliston T, Amirtharajah M, Smad3 binds Scleraxis and Mohawk and regulates tendon matrix organization. J Orthop Res. 2013 Sep;31(9):1475-83 |
1* | J:161299 Ito Y, Toriuchi N, Yoshitaka T, Ueno-Kudoh H, Sato T, Yokoyama S, Nishida K, Akimoto T, Takahashi M, Miyaki S, Asahara H, The Mohawk homeobox gene is a critical regulator of tendon differentiation. Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10538-42 |
1 | J:175747 Liu W, Watson SS, Lan Y, Keene DR, Ovitt CE, Liu H, Schweitzer R, Jiang R, The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis. Mol Cell Biol. 2010 Oct;30(20):4797-807 |
Mlec malectin (Synonyms: 2410014A08Rik, ESTM19, mKIAA0152) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Mlf1 myeloid leukemia factor 1 (Synonyms: HLS7) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Mlh1 mutL homolog 1 (Synonyms: 1110035C23Rik, colon cancer, nonpolyposis type 2) | |
Results | Reference |
1 | J:361445 Ito M, Yun Y, Kulkarni DS, Lee S, Sandhu S, Nunez B, Hu L, Lee K, Lim N, Hirota RM, Prendergast R, Huang C, Huang I, Hunter N, Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis. Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2412961121 |
Mlkl mixed lineage kinase domain-like (Synonyms: 9130019I15Rik) | |
Results | Reference |
1* | J:265712 Dziedzic SA, Su Z, Jean Barrett V, Najafov A, Mookhtiar AK, Amin P, Pan H, Sun L, Zhu H, Ma A, Abbott DW, Yuan J, ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC. Nat Cell Biol. 2018 Jan;20(1):58-68 |
Mllt1 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 1 (Synonyms: BAM11, ENL, LTG19) | |
Results | Reference |
1* | J:143543 Vogel T, Gruss P, Expression of Leukaemia associated transcription factor Af9/Mllt3 in the cerebral cortex of the mouse. Gene Expr Patterns. 2009 Feb;9(2):83-93 |
1 | J:363737 Xue Z, Xuan H, Lau K, Su Y, Wegener M, Li K, Turner L, Adams M, Shi X, Wen H, Expression of ENL YEATS domain tumor mutations in nephrogenic or stromal lineage impairs kidney development. Nat Commun. 2025 Mar 14;16(1):2531 |
Mllt3 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3 (Synonyms: 2210011H10Rik, 2610012I03Rik, 3830408D16Rik, Af9, D4Ertd321e) | |
Results | Reference |
2* | J:143543 Vogel T, Gruss P, Expression of Leukaemia associated transcription factor Af9/Mllt3 in the cerebral cortex of the mouse. Gene Expr Patterns. 2009 Feb;9(2):83-93 |
Mllt6 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 6 (Synonyms: Af17) | |
Results | Reference |
1* | J:169020 Zhang Z, Huang L, Reisenauer MR, Wu H, Chen L, Zhang Y, Xia Y, Zhang W, Widely expressed Af17 is likely not required for embryogenesis, hematopoiesis, and animal survival. Genesis. 2010 Dec;48(12):693-706 |
Mllt11 myeloid/lymphoid or mixed-lineage leukemia; translocated to, 11 (Synonyms: Af1q) | |
Results | Reference |
2* | J:333828 Blommers M, Stanton-Turcotte D, Iulianella A, Retinal neuroblast migration and ganglion cell layer organization require the cytoskeletal-interacting protein Mllt11. Dev Dyn. 2023 Feb;252(2):305-319 |
1* | J:346886 Blommers M, Stanton-Turcotte D, Witt EA, Heidari M, Iulianella A, Cerebellar granule cell migration and folia development require Mllt11/Af1q/Tcf7c. Dev Neurobiol. 2024 Mar 20; |
1* | J:324710 Stanton-Turcotte D, Hsu K, Moore SA, Yamada M, Fawcett JP, Iulianella A, Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development. J Neurosci. 2022 May 11;42(19):3931-3948 |
3* | J:214315 Yamada M, Clark J, Iulianella A, MLLT11/AF1q is differentially expressed in maturing neurons during development. Gene Expr Patterns. 2014 Jul;15(2):80-7 |
Mlxipl MLX interacting protein-like (Synonyms: bHLHd14, ChREBP, Wbscr14, WS-bHLH) | |
Results | Reference |
1* | J:67982 Cairo S, Merla G, Urbinati F, Ballabio A, Reymond A, WBSCR14, a gene mapping to the Williams--Beuren syndrome deleted region, is a new member of the Mlx transcription factor network. Hum Mol Genet. 2001 Mar 15;10(6):617-27 |
2 | J:182863 Gao N, Le Lay J, Qin W, Doliba N, Schug J, Fox AJ, Smirnova O, Matschinsky FM, Kaestner KH, Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell. Mol Endocrinol. 2010 Aug;24(8):1594-604 |
Mmachc methylmalonic aciduria cblC type, with homocystinuria (Synonyms: 1810037K07Rik) | |
Results | Reference |
2 | J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134 |
Mmadhc methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria (Synonyms: 2010311D03Rik) | |
Results | Reference |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Mmd2 monocyte to macrophage differentiation-associated 2 | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Mme membrane metallo endopeptidase (Synonyms: 6030454K05Rik, CD10, NEP, neprilysin, neutral endopeptidase) | |
Results | Reference |
2 | J:17719 Landry C, Huet C, Mangeat P, Sahuquet A, Louvard D, Crine P, Comparative analysis of neutral endopeptidase (NEP) and villin gene expression during mouse embryogenesis and enterocyte maturation. Differentiation. 1994 Apr;56(1-2):55-65 |
Mmp2 matrix metallopeptidase 2 (Synonyms: 72kDa gelatinase, 72kDa type IV collagenase, Clg4a, GelA, gelatinase A, MMP-2) | |
Results | Reference |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1* | J:26819 Gack S, Vallon R, Schmidt J, Grigoriadis A, Tuckermann J, Schenkel J, Weiher H, Wagner EF, Angel P, Expression of interstitial collagenase during skeletal development of the mouse is restricted to osteoblast-like cells and hypertrophic chondrocytes. Cell Growth Differ. 1995 Jun;6(6):759-67 |
1 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
2 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:117794 Sakakura Y, Hosokawa Y, Tsuruga E, Irie K, Nakamura M, Yajima T, Constributions of matrix metalloproteinases toward Meckel's cartilage resorption in mice: immunohistochemical studies, including comparisons with developing endochondral bones. Cell Tissue Res. 2006 Apr;328(1):137-51 |
1 | J:124169 Sakakura Y, Hosokawa Y, Tsuruga E, Irie K, Yajima T, In situ localization of gelatinolytic activity during development and resorption of Meckel's cartilage in mice. Eur J Oral Sci. 2007 Jun;115(3):212-23 |
2* | J:273625 Takahashi M, Fujikawa K, Angammana R, Shibata S, An in situ hybridization study of MMP-2, -9, -13, -14, TIMP-1, and -2 mRNA in fetal mouse mandibular condylar cartilage as compared with limb bud cartilage. Gene Expr Patterns. 2019 Feb 27;32:1-11 |
2* | J:53323 Teesalu T, Masson R, Basset P, Blasi F, Talarico D, Expression of matrix metalloproteinases during murine chorioallantoic placenta maturation. Dev Dyn. 1999 Mar;214(3):248-58 |
1 | J:85488 Yoshiba N, Yoshiba K, Stoetzel C, Perrin-Schmitt F, Cam Y, Ruch JV, Lesot H, Temporospatial gene expression and protein localization of matrix metalloproteinases and their inhibitors during mouse molar tooth development. Dev Dyn. 2003 Sep;228(1):105-12 |
Mmp3 matrix metallopeptidase 3 (Synonyms: progelatinase, SLN-1, SLN1, Stmy1, Str1, STR-1, stromelysin 1, stromelysin-1) | |
Results | Reference |
2 | J:198427 Dudok JJ, Sanz AS, Lundvig DM, Wijnholds J, MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. J Neurosci. 2013 May 8;33(19):8518-27 |
1 | J:163484 Lin MH, Chang KW, Lin SC, Miner JH, Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling. Dev Biol. 2010 Aug 15;344(2):707-19 |
Mmp7 matrix metallopeptidase 7 (Synonyms: MAT, matrilysin) | |
Results | Reference |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1* | J:26885 Wilson CL, Heppner KJ, Rudolph LA, Matrisian LM, The metalloproteinase matrilysin is preferentially expressed by epithelial cells in a tissue-restricted pattern in the mouse. Mol Biol Cell. 1995 Jul;6(7):851-69 |
Mmp8 matrix metallopeptidase 8 (Synonyms: Collagenase-2) | |
Results | Reference |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
Mmp9 matrix metallopeptidase 9 (Synonyms: B/MMP9, Clg4b, gelatinase B, Gelatinase B, Gel B, MMP-9) | |
Results | Reference |
2* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1* | J:66902 Colnot C, Sidhu SS, Balmain N, Poirier F, Uncoupling of chondrocyte death and vascular invasion in mouse galectin 3 null mutant bones. Dev Biol. 2001 Jan 1;229(1):203-14 |
1 | J:163382 Foronjy R, Imai K, Shiomi T, Mercer B, Sklepkiewicz P, Thankachen J, Bodine P, D'Armiento J, The divergent roles of secreted frizzled related protein-1 (SFRP1) in lung morphogenesis and emphysema. Am J Pathol. 2010 Aug;177(2):598-607 |
1 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1 | J:122952 Hung IH, Yu K, Lavine KJ, Ornitz DM, FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. Dev Biol. 2007 Jul 15;307(2):300-13 |
1 | J:119288 Jacob AL, Smith C, Partanen J, Ornitz DM, Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation. Dev Biol. 2006 Aug 15;296(2):315-28 |
1* | J:331874 Lee H, Kim DW, Deletion of ATAD3A inhibits osteogenesis by impairing mitochondria structure and function in pre-osteoblast. Dev Dyn. 2022 Dec;251(12):1982-2000 |
1* | J:74493 Maes C, Carmeliet P, Moermans K, Stockmans I, Smets N, Collen D, Bouillon R, Carmeliet G, Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF(164) and VEGF(188). Mech Dev. 2002 Feb;111(1-2):61-73 |
1 | J:182340 Michikami I, Fukushi T, Tanaka M, Egusa H, Maeda Y, Ooshima T, Wakisaka S, Abe M, Kruppel-like factor 4 regulates membranous and endochondral ossification. Exp Cell Res. 2012 Feb 15;318(4):311-25 |
1 | J:149225 Miclea RL, Karperien M, Bosch CA, van der Horst G, van der Valk MA, Kobayashi T, Kronenberg HM, Rawadi G, Akcakaya P, Lowik CW, Fodde R, Wit JM, Robanus-Maandag EC, Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors. BMC Dev Biol. 2009;9:26 |
1 | J:236002 Miura S, Kondo J, Takimoto A, Sano-Takai H, Guo L, Shukunami C, Tanaka H, Hiraki Y, The N-terminal cleavage of chondromodulin-I in growth-plate cartilage at the hypertrophic and calcified zones during bone development. PLoS One. 2014;9(4):e94239 |
1 | J:112197 Nie X, Luukko K, Fjeld K, Kvinnsland IH, Kettunen P, Developmental expression of Dkk1-3 and Mmp9 and apoptosis in cranial base of mice. J Mol Histol. 2005 Sep;36(6-7):419-26 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1 | J:258274 Patra D, DeLassus E, Mueller J, Abou-Ezzi G, Sandell LJ, Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice. Biol Open. 2018 Feb 22;7(2):bio032094 |
1* | J:17814 Reponen P, Sahlberg C, Munaut C, Thesleff I, Tryggvason K, High expression of 92-kD type IV collagenase (gelatinase B) in the osteoclast lineage during mouse development. J Cell Biol. 1994 Mar;124(6):1091-1102 |
2 | J:47204 Rice DP, Kim HJ, Thesleff I, Detection of gelatinase B expression reveals osteoclastic bone resorption as a feature of early calvarial bone development. Bone. 1997 Dec;21(6):479-86 |
1 | J:321171 Safwan-Zaiter H, Wagner N, Michiels JF, Wagner KD, Dynamic Spatiotemporal Expression Pattern of the Senescence-Associated Factor p16Ink4a in Development and Aging. Cells. 2022 Feb 4;11(3) |
1 | J:117794 Sakakura Y, Hosokawa Y, Tsuruga E, Irie K, Nakamura M, Yajima T, Constributions of matrix metalloproteinases toward Meckel's cartilage resorption in mice: immunohistochemical studies, including comparisons with developing endochondral bones. Cell Tissue Res. 2006 Apr;328(1):137-51 |
1 | J:124169 Sakakura Y, Hosokawa Y, Tsuruga E, Irie K, Yajima T, In situ localization of gelatinolytic activity during development and resorption of Meckel's cartilage in mice. Eur J Oral Sci. 2007 Jun;115(3):212-23 |
1 | J:180852 Sharov AA, Schroeder M, Sharova TY, Mardaryev AN, Peters EM, Tobin DJ, Botchkarev VA, Matrix metalloproteinase-9 is involved in the regulation of hair canal formation. J Invest Dermatol. 2011 Jan;131(1):257-60 |
1 | J:141868 Shinoda Y, Ogata N, Higashikawa A, Manabe I, Shindo T, Yamada T, Kugimiya F, Ikeda T, Kawamura N, Kawasaki Y, Tsushima K, Takeda N, Nagai R, Hoshi K, Nakamura K, Chung UI, Kawaguchi H, Kruppel-like factor 5 causes cartilage degradation through transactivation of matrix metalloproteinase 9. J Biol Chem. 2008 Sep 5;283(36):24682-9 |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
1* | J:80666 Smits P, Li P, Mandel J, Zhang Z, Deng JM, Behringer RR, de Croumbrugghe B, Lefebvre V, The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001 Aug;1(2):277-90 |
2* | J:273625 Takahashi M, Fujikawa K, Angammana R, Shibata S, An in situ hybridization study of MMP-2, -9, -13, -14, TIMP-1, and -2 mRNA in fetal mouse mandibular condylar cartilage as compared with limb bud cartilage. Gene Expr Patterns. 2019 Feb 27;32:1-11 |
1 | J:125052 Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H, Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification. Mol Cell Biol. 2007 Aug;27(16):5650-63 |
2* | J:53323 Teesalu T, Masson R, Basset P, Blasi F, Talarico D, Expression of matrix metalloproteinases during murine chorioallantoic placenta maturation. Dev Dyn. 1999 Mar;214(3):248-58 |
1 | J:326699 Tosun B, Wolff LI, Houben A, Nutt S, Hartmann C, Osteoclasts and Macrophages-Their Role in Bone Marrow Cavity Formation During Mouse Embryonic Development. J Bone Miner Res. 2022 Jun 11; |
1* | J:104555 Viviano BL, Silverstein L, Pflederer C, Paine-Saunders S, Mills K, Saunders S, Altered hematopoiesis in glypican-3-deficient mice results in decreased osteoclast differentiation and a delay in endochondral ossification. Dev Biol. 2005 Jun 1;282(1):152-62 |
1 | J:132462 Wang K, Yamamoto H, Chin JR, Werb Z, Vu TH, Epidermal growth factor receptor-deficient mice have delayed primary endochondral ossification because of defective osteoclast recruitment. J Biol Chem. 2004 Dec 17;279(51):53848-56 |
1 | J:172737 Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RA, Peterson AS, Solloway MJ, Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol. 2011 May 30;193(5):935-51 |
1 | J:85488 Yoshiba N, Yoshiba K, Stoetzel C, Perrin-Schmitt F, Cam Y, Ruch JV, Lesot H, Temporospatial gene expression and protein localization of matrix metalloproteinases and their inhibitors during mouse molar tooth development. Dev Dyn. 2003 Sep;228(1):105-12 |
1 | J:87592 Zhou HM, Weskamp G, Chesneau V, Sahin U, Vortkamp A, Horiuchi K, Chiusaroli R, Hahn R, Wilkes D, Fisher P, Baron R, Manova K, Basson CT, Hempstead B, Blobel CP, Essential role for ADAM19 in cardiovascular morphogenesis. Mol Cell Biol. 2004 Jan;24(1):96-104 |
Mmp11 matrix metallopeptidase 11 (Synonyms: ST3, Stmy3, stromelysin 3) | |
Results | Reference |
1 | J:331894 Alcantara MC, Suzuki K, Acebedo AR, Kajioka D, Hirohata S, Kaisho T, Hatano Y, Yamagata K, Takahashi S, Yamada G, Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice. iScience. 2022 Dec 22;25(12):105609 |
2* | J:24334 Lefebvre O, Regnier C, Chenard MP, Wendling C, Chambon P, Basset P, Rio MC, Developmental expression of mouse stromelysin-3 mRNA. Development. 1995 Apr;121(4):947-55 |
2* | J:53323 Teesalu T, Masson R, Basset P, Blasi F, Talarico D, Expression of matrix metalloproteinases during murine chorioallantoic placenta maturation. Dev Dyn. 1999 Mar;214(3):248-58 |
Mmp13 matrix metallopeptidase 13 (Synonyms: Clg, collagenase-1, Collagenase-3, interstitial collagenase, Mmp1, MMP-13) | |
Results | Reference |
2 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
1 | J:251599 Chen W, Chen L, Zhang Z, Meng F, Huang G, Sheng P, Zhang Z, Liao W, MicroRNA-455-3p modulates cartilage development and degeneration through modification of histone H3 acetylation. Biochim Biophys Acta. 2016 Dec;1863(12):2881-2891 |
3* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:97179 Colnot C, de la Fuente L, Huang S, Hu D, Lu C, St-Jacques B, Helms JA, Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development. Development. 2005 Mar;132(5):1057-67 |
1 | J:230611 Dierker T, Bachvarova V, Krause Y, Li JP, Kjellen L, Seidler DG, Vortkamp A, Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones. Matrix Biol. 2016 Jan;49:82-92 |
1 | J:273365 Dong Y, Yang L, Luo W, Zhu T, Yan W, Kong J, Yuan Z, Zhao Q, Mannose receptor C type 2 mediates 1,25(OH)2D3/vitamin D receptor-regulated collagen metabolism through collagen type 5, alpha 2 chain and matrix metalloproteinase 13 in murine MC3T3-E1 cells. Mol Cell Endocrinol. 2019 Mar 1;483:74-86 |
2* | J:26819 Gack S, Vallon R, Schmidt J, Grigoriadis A, Tuckermann J, Schenkel J, Weiher H, Wagner EF, Angel P, Expression of interstitial collagenase during skeletal development of the mouse is restricted to osteoblast-like cells and hypertrophic chondrocytes. Cell Growth Differ. 1995 Jun;6(6):759-67 |
1 | J:185118 Galli GG, Honnens de Lichtenberg K, Carrara M, Hans W, Wuelling M, Mentz B, Multhaupt HA, Fog CK, Jensen KT, Rappsilber J, Vortkamp A, Coulton L, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Calogero RA, Couchman JR, Lund AH, Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone. PLoS Genet. 2012 May;8(5):e1002711 |
1 | J:150187 Guo X, Mak KK, Taketo MM, Yang Y, The Wnt/beta-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturation. PLoS One. 2009;4(6):e6067 |
1 | J:159025 Hattori T, Muller C, Gebhard S, Bauer E, Pausch F, Schlund B, Bosl MR, Hess A, Surmann-Schmitt C, von der Mark H, de Crombrugghe B, von der Mark K, SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification. Development. 2010 Mar;137(6):901-11 |
1 | J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132 |
1 | J:237341 Houben A, Kostanova-Poliakova D, Weissenbock M, Graf J, Teufel S, von der Mark K, Hartmann C, beta-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis. Development. 2016 Oct 15;143(20):3826-3838 |
1* | J:103991 Ijiri K, Zerbini LF, Peng H, Correa RG, Lu B, Walsh N, Zhao Y, Taniguchi N, Huang XL, Otu H, Wang H, Wang JF, Komiya S, Ducy P, Rahman MU, Flavell RA, Gravallese EM, Oettgen P, Libermann TA, Goldring MB, A novel role for GADD45beta as a mediator of MMP-13 gene expression during chondrocyte terminal differentiation. J Biol Chem. 2005 Nov 18;280(46):38544-55 |
1* | J:54095 Inada M, Yasui T, Nomura S, Miyake S, Deguchi K, Himeno M, Sato M, Yamagiwa H, Kimura T, Yasui N, Ochi T, Endo N, Kitamura Y, Kishimoto T, Komori T, Maturational disturbance of chondrocytes in Cbfa1-deficient mice. Dev Dyn. 1999 Apr;214(4):279-90 |
1 | J:188305 Ishijima M, Suzuki N, Hozumi K, Matsunobu T, Kosaki K, Kaneko H, Hassell JR, Arikawa-Hirasawa E, Yamada Y, Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation. Matrix Biol. 2012 May;31(4):234-45 |
1 | J:92212 Koziel L, Kunath M, Kelly OG, Vortkamp A, Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification. Dev Cell. 2004 Jun;6(6):801-13 |
1 | J:102448 Kugimiya F, Kawaguchi H, Kamekura S, Chikuda H, Ohba S, Yano F, Ogata N, Katagiri T, Harada Y, Azuma Y, Nakamura K, Chung UI, Involvement of endogenous bone morphogenetic protein (BMP) 2 and BMP6 in bone formation. J Biol Chem. 2005 Oct 21;280(42):35704-12 |
1* | J:331874 Lee H, Kim DW, Deletion of ATAD3A inhibits osteogenesis by impairing mitochondria structure and function in pre-osteoblast. Dev Dyn. 2022 Dec;251(12):1982-2000 |
1 | J:268341 Lee SY, Abel ED, Long F, Glucose metabolism induced by Bmp signaling is essential for murine skeletal development. Nat Commun. 2018 Nov 16;9(1):4831 |
1* | J:355649 Li Q, Jiang S, Lei K, Han H, Chen Y, Lin W, Xiong Q, Qi X, Gan X, Sheng R, Wang Y, Zhang Y, Ma J, Li T, Lin S, Zhou C, Chen D, Yuan Q, Metabolic rewiring during bone development underlies tRNA m7G-associated primordial dwarfism. J Clin Invest. 2024 Sep 10;134(20) |
1* | J:85738 MacLean HE, Kim JI, Glimcher MJ, Wang J, Kronenberg HM, Glimcher LH, Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development. Dev Biol. 2003 Oct 1;262(1):51-63 |
1* | J:289776 Mao G, Kang Y, Lin R, Hu S, Zhang Z, Li H, Liao W, Zhang Z, Long Non-coding RNA HOTTIP Promotes CCL3 Expression and Induces Cartilage Degradation by Sponging miR-455-3p. Front Cell Dev Biol. 2019;7:161 |
1 | J:296737 Matsuura VKSK, Yoshida CA, Komori H, Sakane C, Yamana K, Jiang Q, Komori T, Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice. Int J Mol Sci. 2020 Apr 12;21(8):2682 |
1* | J:234972 McDermott BT, Ellis S, Bou-Gharios G, Clegg PD, Tew SR, RNA binding proteins regulate anabolic and catabolic gene expression in chondrocytes. Osteoarthritis Cartilage. 2016 Jul;24(7):1263-73 |
1 | J:182340 Michikami I, Fukushi T, Tanaka M, Egusa H, Maeda Y, Ooshima T, Wakisaka S, Abe M, Kruppel-like factor 4 regulates membranous and endochondral ossification. Exp Cell Res. 2012 Feb 15;318(4):311-25 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:236002 Miura S, Kondo J, Takimoto A, Sano-Takai H, Guo L, Shukunami C, Tanaka H, Hiraki Y, The N-terminal cleavage of chondromodulin-I in growth-plate cartilage at the hypertrophic and calcified zones during bone development. PLoS One. 2014;9(4):e94239 |
1 | J:318774 Monemdjou R, Vasheghani F, Fahmi H, Perez G, Blati M, Taniguchi N, Lotz M, St-Arnaud R, Pelletier JP, Martel-Pelletier J, Beier F, Kapoor M, Association of cartilage-specific deletion of peroxisome proliferator-activated receptor gamma with abnormal endochondral ossification and impaired cartilage growth and development in a murine model. Arthritis Rheum. 2012 May;64(5):1551-61 |
1 | J:316165 Nakamura E, Hata K, Takahata Y, Kurosaka H, Abe M, Abe T, Kihara M, Komori T, Kobayashi S, Murakami T, Inubushi T, Yamashiro T, Yamamoto S, Akiyama H, Kawaguchi M, Sakata N, Nishimura R, Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice. Commun Biol. 2021 Nov 3;4(1):1258 |
1 | J:191589 Nishimura R, Wakabayashi M, Hata K, Matsubara T, Honma S, Wakisaka S, Kiyonari H, Shioi G, Yamaguchi A, Tsumaki N, Akiyama H, Yoneda T, Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification. J Biol Chem. 2012 Sep 28;287(40):33179-90 |
1 | J:316655 Oh SK, Shin JO, Baek JI, Lee J, Bae JW, Ankamerddy H, Kim MJ, Huh TL, Ryoo ZY, Kim UK, Bok J, Lee KY, Pannexin 3 is required for normal progression of skeletal development in vertebrates. FASEB J. 2015 Nov;29(11):4473-84 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1 | J:258274 Patra D, DeLassus E, Mueller J, Abou-Ezzi G, Sandell LJ, Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice. Biol Open. 2018 Feb 22;7(2):bio032094 |
1 | J:219841 Qin X, Jiang Q, Matsuo Y, Kawane T, Komori H, Moriishi T, Taniuchi I, Ito K, Kawai Y, Rokutanda S, Izumi S, Komori T, Cbfb regulates bone development by stabilizing runx family proteins. J Bone Miner Res. 2015 Apr;30(4):706-14 |
1 | J:299239 Qin X, Jiang Q, Nagano K, Moriishi T, Miyazaki T, Komori H, Ito K, Mark KV, Sakane C, Kaneko H, Komori T, Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts. PLoS Genet. 2020 Nov;16(11):e1009169 |
1 | J:117794 Sakakura Y, Hosokawa Y, Tsuruga E, Irie K, Nakamura M, Yajima T, Constributions of matrix metalloproteinases toward Meckel's cartilage resorption in mice: immunohistochemical studies, including comparisons with developing endochondral bones. Cell Tissue Res. 2006 Apr;328(1):137-51 |
1 | J:124169 Sakakura Y, Hosokawa Y, Tsuruga E, Irie K, Yajima T, In situ localization of gelatinolytic activity during development and resorption of Meckel's cartilage in mice. Eur J Oral Sci. 2007 Jun;115(3):212-23 |
1 | J:187998 Shung CY, Ota S, Zhou ZQ, Keene DR, Hurlin PJ, Disruption of a Sox9-beta-catenin circuit by mutant Fgfr3 in thanatophoric dysplasia type II. Hum Mol Genet. 2012 Nov 1;21(21):4628-44 |
1 | J:191584 Sueyoshi T, Yamamoto K, Akiyama H, Conditional deletion of Tgfbr2 in hypertrophic chondrocytes delays terminal chondrocyte differentiation. Matrix Biol. 2012 Jul;31(6):352-9 |
2* | J:273625 Takahashi M, Fujikawa K, Angammana R, Shibata S, An in situ hybridization study of MMP-2, -9, -13, -14, TIMP-1, and -2 mRNA in fetal mouse mandibular condylar cartilage as compared with limb bud cartilage. Gene Expr Patterns. 2019 Feb 27;32:1-11 |
1 | J:132462 Wang K, Yamamoto H, Chin JR, Werb Z, Vu TH, Epidermal growth factor receptor-deficient mice have delayed primary endochondral ossification because of defective osteoclast recruitment. J Biol Chem. 2004 Dec 17;279(51):53848-56 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1* | J:307192 Yadav PS, Feng S, Cong Q, Kim H, Liu Y, Yang Y, Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
1* | J:334015 Yoshioka H, Komura S, Kuramitsu N, Goto A, Hasegawa T, Amizuka N, Ishimoto T, Ozasa R, Nakano T, Imai Y, Akiyama H, Deletion of Tfam in Prx1-Cre expressing limb mesenchyme results in spontaneous bone fractures. J Bone Miner Metab. 2022 Sep;40(5):839-852 |
Mmp14 matrix metallopeptidase 14 (membrane-inserted) (Synonyms: Membrane type 1-MMP, MT1-MMP, sabe) | |
Results | Reference |
1 | J:185530 Chan KM, Wong HL, Jin G, Liu B, Cao R, Cao Y, Lehti K, Tryggvason K, Zhou Z, MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis. Dev Cell. 2012 Jun 12;22(6):1176-90 |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:318016 Otani S, Kakinuma S, Kamiya A, Goto F, Kaneko S, Miyoshi M, Tsunoda T, Asano Y, Kawai-Kitahata F, Nitta S, Nakata T, Okamoto R, Itsui Y, Nakagawa M, Azuma S, Asahina Y, Yamaguchi T, Koshikawa N, Seiki M, Nakauchi H, Watanabe M, Matrix metalloproteinase-14 mediates formation of bile ducts and hepatic maturation of fetal hepatic progenitor cells. Biochem Biophys Res Commun. 2016 Jan 22;469(4):1062-8 |
1 | J:117794 Sakakura Y, Hosokawa Y, Tsuruga E, Irie K, Nakamura M, Yajima T, Constributions of matrix metalloproteinases toward Meckel's cartilage resorption in mice: immunohistochemical studies, including comparisons with developing endochondral bones. Cell Tissue Res. 2006 Apr;328(1):137-51 |
2* | J:273625 Takahashi M, Fujikawa K, Angammana R, Shibata S, An in situ hybridization study of MMP-2, -9, -13, -14, TIMP-1, and -2 mRNA in fetal mouse mandibular condylar cartilage as compared with limb bud cartilage. Gene Expr Patterns. 2019 Feb 27;32:1-11 |
1 | J:125052 Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H, Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification. Mol Cell Biol. 2007 Aug;27(16):5650-63 |
1 | J:132462 Wang K, Yamamoto H, Chin JR, Werb Z, Vu TH, Epidermal growth factor receptor-deficient mice have delayed primary endochondral ossification because of defective osteoclast recruitment. J Biol Chem. 2004 Dec 17;279(51):53848-56 |
2 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
2 | J:85488 Yoshiba N, Yoshiba K, Stoetzel C, Perrin-Schmitt F, Cam Y, Ruch JV, Lesot H, Temporospatial gene expression and protein localization of matrix metalloproteinases and their inhibitors during mouse molar tooth development. Dev Dyn. 2003 Sep;228(1):105-12 |
Mmp17 matrix metallopeptidase 17 (Synonyms: membrane type-4 matrix metalloproteinase, MT4-MMP) | |
Results | Reference |
1* | J:250407 Blanco MJ, Rodriguez-Martin I, Learte AIR, Clemente C, Montalvo MG, Seiki M, Arroyo AG, Sanchez-Camacho C, Developmental expression of membrane type 4-matrix metalloproteinase (Mt4-mmp/Mmp17) in the mouse embryo. PLoS One. 2017;12(9):e0184767 |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:249048 Martin-Alonso M, Garcia-Redondo AB, Guo D, Camafeita E, Martinez F, Alfranca A, Mendez-Barbero N, Pollan A, Sanchez-Camacho C, Denhardt DT, Seiki M, Vazquez J, Salaices M, Redondo JM, Milewicz D, Arroyo AG, Deficiency of MMP17/MT4-MMP proteolytic activity predisposes to aortic aneurysm in mice. Circ Res. 2015 Jul 3;117(2):e13-26 |
Mmp20 matrix metallopeptidase 20 (enamelysin) | |
Results | Reference |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1 | J:174111 Kuchler EC, Menezes R, Callahan N, Costa MC, Modesto A, Meira R, Patir A, Seymen F, Paiva KB, Nunes FD, Granjeiro JM, Vieira AR, MMP1 and MMP20 contribute to tooth agenesis in humans. Arch Oral Biol. 2011 May;56(5):506-11 |
1 | J:188148 Landin MA, Shabestari M, Babaie E, Reseland JE, Osmundsen H, Gene Expression Profiling during Murine Tooth Development. Front Genet. 2012;3:139 |
Mmp21 matrix metallopeptidase 21 (Synonyms: b2b2458Clo, b2b873Clo) | |
Results | Reference |
1* | J:87111 Ahokas K, Lohi J, Illman SA, Llano E, Elomaa O, Impola U, Karjalainen-Lindsberg ML, Saarialho-Kere U, Matrix metalloproteinase-21 is expressed epithelially during development and in cancer and is up-regulated by transforming growth factor-beta1 in keratinocytes. Lab Invest. 2003 Dec;83(12):1887-99 |
Mmrn1 multimerin 1 (Synonyms: 4921530G03Rik, Emilin4) | |
Results | Reference |
2* | J:88794 Braghetta P, Ferrari A, De Gemmis P, Zanetti M, Volpin D, Bonaldo P, Bressan GM, Overlapping, complementary and site-specific expression pattern of genes of the EMILIN/Multimerin family. Matrix Biol. 2004 Jan;22(7):549-56 |
Mmrn2 multimerin 2 (Synonyms: Emilin3, EndoGlyx-1, ENDOGLYX1) | |
Results | Reference |
2* | J:88794 Braghetta P, Ferrari A, De Gemmis P, Zanetti M, Volpin D, Bonaldo P, Bressan GM, Overlapping, complementary and site-specific expression pattern of genes of the EMILIN/Multimerin family. Matrix Biol. 2004 Jan;22(7):549-56 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Mnx1 motor neuron and pancreas homeobox 1 (Synonyms: HB9, Hlxb9, MNR2) | |
Results | Reference |
1 | J:57340 Arber S, Han B, Mendelsohn M, Smith M, Jessell TM, Sockanathan S, Requirement for the homeobox gene Hb9 in the consolidation of motor neuron identity. Neuron. 1999 Aug;23(4):659-74 |
1 | J:262472 Edmond M, Hanley O, Philippidou P, Topoisomerase IIbeta Selectively Regulates Motor Neuron Identity and Peripheral Connectivity through Hox/Pbx-Dependent Transcriptional Programs. eNeuro. 2017 Nov-Dec;4(6):ENEURO.0404-17.2017 |
1 | J:235955 Laitman BM, Asp L, Mariani JN, Zhang J, Liu J, Sawai S, Chapouly C, Horng S, Kramer EG, Mitiku N, Loo H, Burlant N, Pedre X, Hara Y, Nudelman G, Zaslavsky E, Lee YM, Braun DA, Lu QR, Narla G, Raine CS, Friedman SL, Casaccia P, John GR, The Transcriptional Activator Kruppel-like Factor-6 Is Required for CNS Myelination. PLoS Biol. 2016 May;14(5):e1002467 |
1 | J:178050 Liang X, Song MR, Xu Z, Lanuza GM, Liu Y, Zhuang T, Chen Y, Pfaff SL, Evans SM, Sun Y, Isl1 is required for multiple aspects of motor neuron development. Mol Cell Neurosci. 2011 Jul;47(3):215-22 |
1 | J:239946 Pan FC, Brissova M, Powers AC, Pfaff S, Wright CV, Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing beta-cells to a delta-like fate and reveals a facultative proliferative capacity in aged beta-cells. Development. 2015 Nov 01;142(21):3637-48 |
1 | J:69623 Yang X, Arber S, William C, Li L, Tanabe Y, Jessell TM, Birchmeier C, Burden SJ, Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation. Neuron. 2001 May;30(2):399-410 |
Mob1a MOB kinase activator 1A (Synonyms: 4022402H07Rik, MGC:6884, Mobk1b, Mobkl1b) | |
Results | Reference |
1* | J:243360 Otsubo K, Goto H, Nishio M, Kawamura K, Yanagi S, Nishie W, Sasaki T, Maehama T, Nishina H, Mimori K, Nakano T, Shimizu H, Mak TW, Nakao K, Nakanishi Y, Suzuki A, MOB1-YAP1/TAZ-NKX2.1 axis controls bronchioalveolar cell differentiation, adhesion and tumour formation. Oncogene. 2017 Jul 20;36(29):4201-4211 |
Mok MOK protein kinase (Synonyms: MAPK/MAK/MRK/ overlapping kinase, MOK, Rage, Stk30) | |
Results | Reference |
1 | J:202949 Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J, Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18042-51 |
Morc1 microrchidia 1 | |
Results | Reference |
2 | J:225677 Pastor WA, Stroud H, Nee K, Liu W, Pezic D, Manakov S, Lee SA, Moissiard G, Zamudio N, Bourc'his D, Aravin AA, Clark AT, Jacobsen SE, MORC1 represses transposable elements in the mouse male germline. Nat Commun. 2014;5:5795 |
Morc2b microrchidia 2B (Synonyms: 4932411A10Rik) | |
Results | Reference |
1* | J:102875 Hayashi K, Yoshida K, Matsui Y, A histone H3 methyltransferase controls epigenetic events required for meiotic prophase. Nature. 2005 Nov 17;438(7066):374-8 |
Morc3 microrchidia 3 (Synonyms: 1110051N18Rik, 1110051N18Rik, D16Jhu32e, Nxp-2, Zcwcc3) | |
Results | Reference |
2 | J:312495 Kojima-Kita K, Kuramochi-Miyagawa S, Nakayama M, Miyata H, Jacobsen SE, Ikawa M, Koseki H, Nakano T, MORC3, a novel MIWI2 association partner, as an epigenetic regulator of piRNA dependent transposon silencing in male germ cells. Sci Rep. 2021 Oct 14;11(1):20472 |
Morf4l1 mortality factor 4 like 1 (Synonyms: MORFRG15, MRG15, TEG-189, Tex189) | |
Results | Reference |
1* | J:97640 Tominaga K, Kirtane B, Jackson JG, Ikeno Y, Ikeda T, Hawks C, Smith JR, Matzuk MM, Pereira-Smith OM, MRG15 regulates embryonic development and cell proliferation. Mol Cell Biol. 2005 Apr;25(8):2924-37 |
1* | J:99130 Tominaga K, Matzuk MM, Pereira-Smith OM, MrgX is not essential for cell growth and development in the mouse. Mol Cell Biol. 2005 Jun;25(12):4873-80 |
Morf4l2 mortality factor 4 like 2 (Synonyms: 2410017O14Rik, mKIAA0026, Sid393p) | |
Results | Reference |
1* | J:99130 Tominaga K, Matzuk MM, Pereira-Smith OM, MrgX is not essential for cell growth and development in the mouse. Mol Cell Biol. 2005 Jun;25(12):4873-80 |
Mos Moloney sarcoma oncogene (Synonyms: c-mos) | |
Results | Reference |
1 | J:178367 Slamon DJ, Cline MJ, Expression of cellular oncogenes during embryonic and fetal development of the mouse. Proc Natl Acad Sci U S A. 1984 Nov;81(22):7141-5 |
Mov10l1 Mov10 like RISC complex RNA helicase 1 (Synonyms: CHAMP, Csm) | |
Results | Reference |
1 | J:184034 De Fazio S, Bartonicek N, Di Giacomo M, Abreu-Goodger C, Sankar A, Funaya C, Antony C, Moreira PN, Enright AJ, O'Carroll D, The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements. Nature. 2011 Dec 8;480(7376):259-63 |
2 | J:238224 Fu Q, Pandey RR, Leu NA, Pillai RS, Wang PJ, Mutations in the MOV10L1 ATP Hydrolysis Motif Cause piRNA Biogenesis Failure and Male Sterility in Mice. Biol Reprod. 2016 Nov 1;95(5):103 |
2 | J:221349 Vourekas A, Zheng K, Fu Q, Maragkakis M, Alexiou P, Ma J, Pillai RS, Mourelatos Z, Wang PJ, The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing. Genes Dev. 2015 Mar 15;29(6):617-29 |
Mpl myeloproliferative leukemia virus oncogene (Synonyms: CD110, c-mpl, c-mpl-I, c-mpl-II, hlb219, thrombopoietin receptor, TPO-R) | |
Results | Reference |
1* | J:124109 Petit-Cocault L, Volle-Challier C, Fleury M, Peault B, Souyri M, Dual role of Mpl receptor during the establishment of definitive hematopoiesis. Development. 2007 Aug;134(16):3031-40 |
Mpp1 membrane protein, palmitoylated (Synonyms: 55kDa, C130070C03Rik, erythrocyte protein p55, p55) | |
Results | Reference |
1* | J:143824 Gosens I, van Wijk E, Kersten FF, Krieger E, van der Zwaag B, Marker T, Letteboer SJ, Dusseljee S, Peters T, Spierenburg HA, Punte IM, Wolfrum U, Cremers FP, Kremer H, Roepman R, MPP1 links the Usher protein network and the Crumbs protein complex in the retina. Hum Mol Genet. 2007 Aug 15;16(16):1993-2003 |
Mpp7 membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7) (Synonyms: 1110068J02Rik, 2810038M04Rik, 5430426E14Rik, LOC381166) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Mpped1 metallophosphoesterase domain containing 1 | |
Results | Reference |
2 | J:160586 Chen CM, Wang HY, You LR, Shang RL, Liu FC, Expression analysis of an evolutionary conserved metallophosphodiesterase gene, Mpped1, in the normal and beta-catenin-deficient malformed dorsal telencephalon. Dev Dyn. 2010 Jun;239(6):1797-806 |
Mpz myelin protein zero (Synonyms: Mpp, P0) | |
Results | Reference |
1 | J:178222 Asada N, Takase M, Nakamura J, Oguchi A, Asada M, Suzuki N, Yamamura K, Nagoshi N, Shibata S, Rao TN, Fehling HJ, Fukatsu A, Minegishi N, Kita T, Kimura T, Okano H, Yamamoto M, Yanagita M, Dysfunction of fibroblasts of extrarenal origin underlies renal fibrosis and renal anemia in mice. J Clin Invest. 2011 Oct 3;121(10):3981-90 |
1 | J:288683 Gacem N, Kavo A, Zerad L, Richard L, Mathis S, Kapur RP, Parisot M, Amiel J, Dufour S, de la Grange P, Pingault V, Vallat JM, Bondurand N, ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. Nat Commun. 2020 Jan 10;11(1):198 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Mpzl2 myelin protein zero-like 2 (Synonyms: Eva, Eva1) | |
Results | Reference |
1* | J:121478 DeMonte L, Porcellini S, Tafi E, Sheridan J, Gordon J, Depreter M, Blair N, Panigada M, Sanvito F, Merati B, Albientz A, Barthlott T, Ozmen L, Blackburn CC, Guttinger M, EVA regulates thymic stromal organisation and early thymocyte development. Biochem Biophys Res Commun. 2007 May 4;356(2):334-40 |
1* | J:48229 Guttinger M, Sutti F, Panigada M, Porcellini S, Merati B, Mariani M , Teesalu T , Consalez GG , Grassi F, Epithelial V-like antigen (EVA), a novel member of the immunoglobulin superfamily, expressed in embryonic epithelia with a potential role as homotypic adhesion molecule in thymus histogenesis. J Cell Biol. 1998 May 18;141(4):1061-71 |
1 | J:51692 Teesalu T, Grassi F, Guttinger M, Expression pattern of the epithelial v-like antigen (Eva) transcript suggests a possible role in placental morphogenesis. Dev Genet. 1998;23(4):317-23 |
Mrap melanocortin 2 receptor accessory protein (Synonyms: 1110025G12Rik, C21ORF61) | |
Results | Reference |
1* | J:77361 Gardiner K, Slavov D, Bechtel L, Davisson M, Annotation of human chromosome 21 for relevance to down syndrome: gene structure and expression analysis. Genomics. 2002 Jun;79(6):833-43 |
Mrc1 mannose receptor, C type 1 (Synonyms: CD206, MR) | |
Results | Reference |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
1* | J:333946 Hattori Y, Kato D, Murayama F, Koike S, Asai H, Yamasaki A, Naito Y, Kawaguchi A, Konishi H, Prinz M, Masuda T, Wake H, Miyata T, CD206(+) macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia. Cell Rep. 2023 Feb 7;42(2):112092 |
1 | J:330324 Masuda T, Amann L, Monaco G, Sankowski R, Staszewski O, Krueger M, Del Gaudio F, He L, Paterson N, Nent E, Fernandez-Klett F, Yamasaki A, Frosch M, Fliegauf M, Bosch LFP, Ulupinar H, Hagemeyer N, Schreiner D, Dorrier C, Tsuda M, Grothe C, Joutel A, Daneman R, Betsholtz C, Lendahl U, Knobeloch KP, Lammermann T, Priller J, Kierdorf K, Prinz M, Specification of CNS macrophage subsets occurs postnatally in defined niches. Nature. 2022 Apr;604(7907):740-748 |
1 | J:326459 Scott EP, Breyak E, Nishinakamura R, Nakagawa Y, The zinc finger transcription factor Sall1 is required for the early developmental transition of microglia in mouse embryos. Glia. 2022 Sep;70(9):1720-1733 |
1* | J:48210 Takahashi K, Donovan MJ, Rogers RA, Ezekowitz RA, Distribution of murine mannose receptor expression from early embryogenesis through to adulthood. Cell Tissue Res. 1998 May;292(2):311-23 |
Mrc2 mannose receptor, C type 2 (Synonyms: Endo180, mKIAA0709, novel lectin, uPARAP) | |
Results | Reference |
1 | J:273365 Dong Y, Yang L, Luo W, Zhu T, Yan W, Kong J, Yuan Z, Zhao Q, Mannose receptor C type 2 mediates 1,25(OH)2D3/vitamin D receptor-regulated collagen metabolism through collagen type 5, alpha 2 chain and matrix metalloproteinase 13 in murine MC3T3-E1 cells. Mol Cell Endocrinol. 2019 Mar 1;483:74-86 |
1* | J:138322 Smith L, Wagner TE, Huizar I, Schnapp LM, uPARAP expression during murine lung development. Gene Expr Patterns. 2008 Sep;8(7-8):486-93 |
Mrgpra3 MAS-related GPR, member A3 (Synonyms: G protein-coupled receptor, MrgA3) | |
Results | Reference |
1 | J:242690 Qi L, Huang C, Wu X, Tao Y, Yan J, Shi T, Cao C, Han L, Qiu M, Ma Q, Liu Z, Liu Y, Hierarchical Specification of Pruriceptors by Runt-Domain Transcription Factor Runx1. J Neurosci. 2017 May 31;37(22):5549-5561 |
Mrgprd MAS-related GPR, member D (Synonyms: LOC211578, MrgD) | |
Results | Reference |
1 | J:106971 Chen CL, Broom DC, Liu Y, de Nooij JC, Li Z, Cen C, Samad OA, Jessell TM, Woolf CJ, Ma Q, Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain. Neuron. 2006 Feb 2;49(3):365-77 |
1* | J:186470 Lopes C, Liu Z, Xu Y, Ma Q, Tlx3 and runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors. J Neurosci. 2012 Jul 11;32(28):9706-15 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
Mrnip MRN complex interacting protein (Synonyms: 2900016G09Rik, 3010026O09Rik) | |
Results | Reference |
1 | J:329968 Kazi S, Castaneda JM, Savolainen A, Xu Y, Liu N, Qiao H, Ramirez-Solis R, Nozawa K, Yu Z, Matzuk MM, Prunskaite-Hyyrylainen R, MRNIP interacts with sex body chromatin to support meiotic progression, spermatogenesis, and male fertility in mice. FASEB J. 2022 Sep;36(9):e22479 |
Mrpl42 mitochondrial ribosomal protein L42 (Synonyms: 2700009F22Rik, 2900055D03Rik, D10Ertd322e, HSPC204, MRP-L31, PTD007, Rpml31) | |
Results | Reference |
1 | J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134 |
Mrpl54 mitochondrial ribosomal protein L54 (Synonyms: 0610008M19Rik, D10Sut1e) | |
Results | Reference |
1 | J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Mrps22 mitochondrial ribosomal protein S22 (Synonyms: 3100002P07Rik, Rpms22) | |
Results | Reference |
1 | J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134 |
Mrps25 mitochondrial ribosomal protein S25 (Synonyms: 2810429N01Rik, Rpms25) | |
Results | Reference |
1 | J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134 |
Mrtfb myocardin related transcription factor B (Synonyms: Gt4-1, MGC:41582, Mkl2, Mrtfb, MRTF-B) | |
Results | Reference |
1 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
Ms4a2 membrane-spanning 4-domains, subfamily A, member 2 (Synonyms: Fce1b, Fcer1b, FcRB, Fcrbeta) | |
Results | Reference |
1* | J:31166 Jippo T, Mizuno H, Xu Z, Nomura S, Yamamoto M, Kitamura Y, Abundant expression of transcription factor GATA-2 in proliferating but not in differentiated mast cells in tissues of mice: demonstration by in situ hybridization. Blood. 1996 Feb 1;87(3):993-8 |
Msc musculin (Synonyms: bHLHa22, MyoR) | |
Results | Reference |
2 | J:224301 Harris JP, Bhakta M, Bezprozvannaya S, Wang L, Lubczyk C, Olson EN, Munshi NV, MyoR modulates cardiac conduction by repressing Gata4. Mol Cell Biol. 2015 Feb;35(4):649-61 |
1* | J:52277 Lu J, Webb R, Richardson JA, Olson EN, MyoR: a muscle-restricted basic helix-loop-helix transcription factor that antagonizes the actions of MyoD. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):552-7 |
Msh4 mutS homolog 4 (Synonyms: 4930485C04Rik, mMsh4) | |
Results | Reference |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
Msi1 musashi RNA-binding protein 1 (Synonyms: m-Msi-1, Msi1, Msi1h, Musahi1) | |
Results | Reference |
1 | J:163240 Kuwako K, Kakumoto K, Imai T, Igarashi M, Hamakubo T, Sakakibara S, Tessier-Lavigne M, Okano HJ, Okano H, Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression. Neuron. 2010 Aug 12;67(3):407-21 |
1 | J:124972 Raji B, Dansault A, Leemput J, de la Houssaye G, Vieira V, Kobetz A, Arbogast L, Masson C, Menasche M, Abitbol M, The RNA-binding protein Musashi-1 is produced in the developing and adult mouse eye. Mol Vis. 2007;13:1412-27 |
2* | J:33572 Sakakibara S, Imai T, Hamaguchi K, Okabe M, Aruga J, Nakajima K, Yasutomi D, Nagata T, Kurihara Y, Uesugi S, Miyata T, Ogawa M, Mikoshiba K, Okano H, Mouse-Musashi-1, a neural RNA-binding protein highly enriched in the mammalian CNS stem cell. Dev Biol. 1996 Jun 15;176(2):230-42 |
1* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
Msi2 musashi RNA-binding protein 2 (Synonyms: msi2h, Musashi2) | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1* | J:72036 Sakakibara S, Nakamura Y, Satoh H, Okano H, Rna-binding protein Musashi2: developmentally regulated expression in neural precursor cells and subpopulations of neurons in mammalian CNS. J Neurosci. 2001 Oct 15;21(20):8091-107 |
Msln mesothelin (Synonyms: megakaryocyte potentiating factor, MPF) | |
Results | Reference |
1 | J:161574 Onitsuka I, Tanaka M, Miyajima A, Characterization and functional analyses of hepatic mesothelial cells in mouse liver development. Gastroenterology. 2010 Apr;138(4):1525-35, 1535.e1-6 |
Msmo1 methylsterol monoxygenase 1 (Synonyms: 1500001G16Rik, C78600, DESP4, ERG25, Sc4mol) | |
Results | Reference |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
Msn moesin | |
Results | Reference |
1 | J:263981 Benhamouche-Trouillet S, O'Loughlin E, Liu CH, Polacheck W, Fitamant J, McKee M, El-Bardeesy N, Chen CS, McClatchey AI, Proliferation-independent role of NF2 (merlin) in limiting biliary morphogenesis. Development. 2018 Apr 30;145(9):dev162123 |
1 | J:214064 Tarchini B, Jolicoeur C, Cayouette M, A molecular blueprint at the apical surface establishes planar asymmetry in cochlear hair cells. Dev Cell. 2013 Oct 14;27(1):88-102 |
1 | J:346405 Vitureira N, Andres R, Perez-Martinez E, Martinez A, Bribian A, Blasi J, Chelliah S, Lopez-Domenech G, De Castro F, Burgaya F, McNagny K, Soriano E, Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation. PLoS One. 2010 Aug 10;5(8):e12003 |
Msrb2 methionine sulfoxide reductase B2 (Synonyms: 2310050L06Rik, Msrb) | |
Results | Reference |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
Mst1r macrophage stimulating 1 receptor (c-met-related tyrosine kinase) (Synonyms: CDw136, friend virus susceptibility 2, Fv-2, Fv2, PTK8, Ron, STK) | |
Results | Reference |
2* | J:30853 Gaudino G, Avantaggiato V, Follenzi A, Acampora D, Simeone A, Comoglio PM, The proto-oncogene RON is involved in development of epithelial, bone and neuro-endocrine tissues. Oncogene. 1995 Dec 21;11(12):2627-37 |
1 | J:29943 Quantin B, Schuhbaur B, Gesnel MC, Doll'e P, Breathnach R, Restricted expression of the ron gene encoding the macrophage stimulating protein receptor during mouse development. Dev Dyn. 1995 Dec;204(4):383-90 |
Mstn myostatin (Synonyms: Gdf8) | |
Results | Reference |
1 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
Msx1 msh homeobox 1 (Synonyms: Hox-7, Hox7, Hox7.1, msh, muscle-segment homeobox) | |
Results | Reference |
1 | J:70041 Blin-Wakkach C, Lezot F, Ghoul-Mazgar S, Hotton D, Monteiro S, Teillaud C, Pibouin L, Orestes-Cardoso S, Papagerakis P, Macdougall M, Robert B, Berdal A, Endogenous Msx1 antisense transcript: in vivo and in vitro evidences, structure, and potential involvement in skeleton development in mammals. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7336-41 |
1 | J:309359 Brinkmeier ML, Bando H, Camarano AC, Fujio S, Yoshimoto K, de Souza FS, Camper SA, Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. J Clin Invest. 2020 Aug 3;130(8):4501-4515 |
1 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
3* | J:101319 Coudert AE, Pibouin L, Vi-Fane B, Thomas BL, Macdougall M, Choudhury A, Robert B, Sharpe PT, Berdal A, Lezot F, Expression and regulation of the Msx1 natural antisense transcript during development. Nucleic Acids Res. 2005;33(16):5208-18 |
1 | J:304642 Dupacova N, Antosova B, Paces J, Kozmik Z, Meis homeobox genes control progenitor competence in the retina. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2013136118 |
1 | J:176438 Esteve P, Sandonis A, Ibanez C, Shimono A, Guerrero I, Bovolenta P, Secreted frizzled-related proteins are required for Wnt/{beta}-catenin signalling activation in the vertebrate optic cup. Development. 2011 Oct;138(19):4179-84 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1* | J:86790 Gitler AD, Lu MM, Jiang YQ, Epstein JA, Gruber PJ, Molecular markers of cardiac endocardial cushion development. Dev Dyn. 2003 Dec;228(4):643-50 |
1 | J:239666 Hagglund AC, Jones I, Carlsson L, A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development. Dis Model Mech. 2017 Mar 01;10(3):245-257 |
1 | J:125693 Hanashima C, Fernandes M, Hebert JM, Fishell G, The role of Foxg1 and dorsal midline signaling in the generation of Cajal-Retzius subtypes. J Neurosci. 2007 Oct 10;27(41):11103-11 |
1 | J:332137 Hu H, Duan Y, Wang K, Fu H, Liao Y, Wang T, Zhang Z, Kang F, Zhang B, Zhang H, Huo F, Yin Y, Chen G, Hu H, Cai H, Tian W, Li Z, Dental niche cells directly contribute to tooth reconstitution and morphogenesis. Cell Rep. 2022 Dec 6;41(10):111737 |
1* | J:114410 Jumlongras D, Bei M, Stimson JM, Wang WF, DePalma SR, Seidman CE, Felbor U, Maas R, Seidman JG, Olsen BR, A nonsense mutation in MSX1 causes Witkop syndrome. Am J Hum Genet. 2001 Jul;69(1):67-74 |
1 | J:51084 Keranen SV, Aberg T, Kettunen P, Thesleff I, Jernvall J, Association of developmental regulatory genes with the development of different molar tooth shapes in two species of rodents. Dev Genes Evol. 1998 Nov;208(9):477-86 |
1 | J:336410 Koo HY, Kim MA, Min H, Hwang JY, Prajapati-DiNubila M, Kim KS, Matzuk MM, Park JW, Doetzlhofer A, Kim UK, Bok J, Follistatin regulates the specification of the apical cochlea responsible for low-frequency hearing in mammals. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2213099120 |
1 | J:178676 Le Bouffant R, Souquet B, Duval N, Duquenne C, Herve R, Frydman N, Robert B, Habert R, Livera G, Msx1 and Msx2 promote meiosis initiation. Development. 2011 Dec;138(24):5393-402 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1 | J:184582 Lopes M, Gooupille O, Saint Cloment C, Robert B, Msx1 is expressed in retina endothelial cells at artery branching sites. Biol Open. 2012 Apr 15;1(4):376-384 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1* | J:1570 Lyons GE, Houzelstein D, Sassoon D, Robert B, Buckingham ME, Multiple sites of Hox-7 expression during mouse embryogenesis: comparison with retinoic acid receptor mRNA localization. Mol Reprod Dev. 1992 Aug;32(4):303-14 |
1* | J:20090 Mackenzie A, Leeming GL, Jowett AK, Ferguson MW, Sharpe PT, The homeobox gene Hox 7.1 has specific regional and temporal expression patterns during early murine craniofacial embryogenesis, especially tooth development in vivo and in vitro. Development. 1991 Feb;111(2):269-85 |
1 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
1 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
1* | J:11525 Monaghan AP, Davidson DR, Sime C, Graham E, Baldock R, Bhattacharya SS, Hill RE, The Msh-like homeobox genes define domains in the developing vertebrate eye. Development. 1991 Aug;112(4):1053-61 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:91214 Ramos C, Fernandez-Llebrez P, Bach A, Robert B, Soriano E, Msx1 disruption leads to diencephalon defects and hydrocephalus. Dev Dyn. 2004 Jul;230(3):446-60 |
1 | J:24332 Reginelli AD, Wang YQ, Sassoon D, Muneoka K, Digit tip regeneration correlates with regions of Msx1 (Hox 7) expression in fetal and newborn mice. Development. 1995 Apr;121(4):1065-76 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:217590 Yuan G, Yang G, Zheng Y, Zhu X, Chen Z, Zhang Z, Chen Y, The non-canonical BMP and Wnt/beta-catenin signaling pathways orchestrate early tooth development. Development. 2015 Jan 1;142(1):128-39 |
1 | J:329949 Yuan H, Xie B, Yu X, Lin C, Li M, Zhang Y, Zou X, Lu M, Zhao M, Wen X, A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development. Front Physiol. 2022;13:981311 |
1* | J:87163 Zhang Z, Song Y, Zhang X, Tang J, Chen J, Chen Y, Msx1/Bmp4 genetic pathway regulates mammalian alveolar bone formation via induction of Dlx5 and Cbfa1. Mech Dev. 2003 Dec;120(12):1469-79 |
1* | J:173972 Zhao H, Li S, Han D, Kaartinen V, Chai Y, Alk5-mediated transforming growth factor beta signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol. 2011 May;31(10):2079-89 |
Msx1os msh homeobox 1 opposite strand (Synonyms: Msx1as) | |
Results | Reference |
1 | J:70041 Blin-Wakkach C, Lezot F, Ghoul-Mazgar S, Hotton D, Monteiro S, Teillaud C, Pibouin L, Orestes-Cardoso S, Papagerakis P, Macdougall M, Robert B, Berdal A, Endogenous Msx1 antisense transcript: in vivo and in vitro evidences, structure, and potential involvement in skeleton development in mammals. Proc Natl Acad Sci U S A. 2001 Jun 19;98(13):7336-41 |
2* | J:101319 Coudert AE, Pibouin L, Vi-Fane B, Thomas BL, Macdougall M, Choudhury A, Robert B, Sharpe PT, Berdal A, Lezot F, Expression and regulation of the Msx1 natural antisense transcript during development. Nucleic Acids Res. 2005;33(16):5208-18 |
Msx2 msh homeobox 2 (Synonyms: Hox-8, Hox8, Hox8.1) | |
Results | Reference |
1* | J:74162 Abdelwahid E, Rice D, Pelliniemi LJ, Jokinen E, Overlapping and differential localization of Bmp-2, Bmp-4, Msx-2 and apoptosis in the endocardial cushion and adjacent tissues of the developing mouse heart. Cell Tissue Res. 2001 Jul;305(1):67-78 |
1 | J:91667 Antonopoulou I, Mavrogiannis LA, Wilkie AO, Morriss-Kay GM, Alx4 and Msx2 play phenotypically similar and additive roles in skull vault differentiation. J Anat. 2004 Jun;204(6):487-99 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
2* | J:146765 Golonzhka O, Metzger D, Bornert JM, Bay BK, Gross MK, Kioussi C, Leid M, Ctip2/Bcl11b controls ameloblast formation during mammalian odontogenesis. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4278-83 |
1* | J:4384 Jowett AK, Vainio S, Ferguson MW, Sharpe PT, Thesleff I, Epithelial-mesenchymal interactions are required for msx 1 and msx 2 gene expression in the developing murine molar tooth. Development. 1993 Feb;117(2):461-70 |
1 | J:51084 Keranen SV, Aberg T, Kettunen P, Thesleff I, Jernvall J, Association of developmental regulatory genes with the development of different molar tooth shapes in two species of rodents. Dev Genes Evol. 1998 Nov;208(9):477-86 |
1 | J:178676 Le Bouffant R, Souquet B, Duval N, Duquenne C, Herve R, Frydman N, Robert B, Habert R, Livera G, Msx1 and Msx2 promote meiosis initiation. Development. 2011 Dec;138(24):5393-402 |
1 | J:24332 Reginelli AD, Wang YQ, Sassoon D, Muneoka K, Digit tip regeneration correlates with regions of Msx1 (Hox 7) expression in fetal and newborn mice. Development. 1995 Apr;121(4):1065-76 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:144194 Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72 |
1 | J:140401 Xu X, Han J, Ito Y, Bringas P Jr, Deng C, Chai Y, Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-beta/BMP signaling during tooth and palate development. Dev Cell. 2008 Aug;15(2):322-9 |
Msx3 msh homeobox 3 | |
Results | Reference |
1* | J:35536 Wang W, Chen X, Xu H, Lufkin T, Msx3: a novel murine homologue of the Drosophila msh homeobox gene restricted to the dorsal embryonic central nervous system. Mech Dev. 1996 Aug;58(1-2):203-15 |
Mt1 metallothionein 1 (Synonyms: Mt-1, MT-I) | |
Results | Reference |
1* | J:32998 Choudhuri S, Liu WL, Berman NE, Klaassen CD, Cadmium accumulation and metallothionein expression in brain of mice at different stages of development. Toxicol Lett. 1996 Mar;84(3):127-33 |
1 | J:311844 Landin MA, Nygard S, Shabestari MG, Babaie E, Reseland JE, Osmundsen H, Mapping the global mRNA transcriptome during development of the murine first molar. Front Genet. 2015;6:47 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Mt2 metallothionein 2 (Synonyms: Mt-2, MT-II) | |
Results | Reference |
1* | J:32998 Choudhuri S, Liu WL, Berman NE, Klaassen CD, Cadmium accumulation and metallothionein expression in brain of mice at different stages of development. Toxicol Lett. 1996 Mar;84(3):127-33 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Mt3 metallothionein 3 (Synonyms: MT-3) | |
Results | Reference |
1* | J:32998 Choudhuri S, Liu WL, Berman NE, Klaassen CD, Cadmium accumulation and metallothionein expression in brain of mice at different stages of development. Toxicol Lett. 1996 Mar;84(3):127-33 |
mt-Atp6 mitochondrially encoded ATP synthase 6 (Synonyms: ATPASE6) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
mt-Co1 mitochondrially encoded cytochrome c oxidase I (Synonyms: CCOI, COI, COX 1, COX1, CoxI, mt-Co1-201) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
1* | J:76945 Carmona MC, Iglesias R, Obregon MJ, Darlington GJ, Villarroya F, Giralt M, Mitochondrial biogenesis and thyroid status maturation in brown fat require CCAAT/enhancer-binding protein alpha. J Biol Chem. 2002 Jun 14;277(24):21489-98 |
1 | J:337469 Park A, Kim KE, Park I, Lee SH, Park KY, Jung M, Li X, Sleiman MB, Lee SJ, Kim DS, Kim J, Lim DS, Woo EJ, Lee EW, Han BS, Oh KJ, Lee SC, Auwerx J, Mun JY, Rhee HW, Kim WK, Bae KH, Suh JM, Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice. Nat Commun. 2023 Jun 23;14(1):3746 |
mt-Co2 mitochondrially encoded cytochrome c oxidase II (Synonyms: COXII) | |
Results | Reference |
1* | J:305946 Xu M, Yao J, Shi Y, Yi H, Zhao W, Lin X, Yang Z, The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026 |
mt-Co3 mitochondrially encoded cytochrome c oxidase III (Synonyms: COIII, COX3) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
mt-Nd6 mitochondrially encoded NADH dehydrogenase 6 (Synonyms: ENSMUSG00000064368, URF6) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Mta1 metastasis associated 1 | |
Results | Reference |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
Mtdh metadherin (Synonyms: 2610103J23Rik, 3D3/Lyric, AEG-1, D8Bwg1112e, Lyric) | |
Results | Reference |
2* | J:164029 Jeon HY, Choi M, Howlett EL, Vozhilla N, Yoo BK, Lloyd JA, Sarkar D, Lee SG, Fisher PB, Expression patterns of astrocyte elevated gene-1 (AEG-1) during development of the mouse embryo. Gene Expr Patterns. 2010 October - December;10(7-8):361-367 |
Mtf2 metal response element binding transcription factor 2 (Synonyms: 9230112N11Rik, C76717, M96, Pcl2) | |
Results | Reference |
1* | J:118339 Wang S, He F, Xiong W, Gu S, Liu H, Zhang T, Yu X, Chen Y, Polycomblike-2-deficient mice exhibit normal left-right asymmetry. Dev Dyn. 2007 Mar;236(3):853-61 |
Mtfr1 mitochondrial fission regulator 1 (Synonyms: 1300002C08Rik, 1700080D04Rik, 2810026O10Rik, 4930579E05Rik, Fam54a2) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Mthfd1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase (Synonyms: DCS, E430024A07Rik, Mthfd) | |
Results | Reference |
1* | J:159942 Pike ST, Rajendra R, Artzt K, Appling DR, Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos. J Biol Chem. 2010 Feb 12;285(7):4612-20 |
Mthfd1l methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like (Synonyms: 2410004L15Rik, Fthfsdc1) | |
Results | Reference |
1* | J:159942 Pike ST, Rajendra R, Artzt K, Appling DR, Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos. J Biol Chem. 2010 Feb 12;285(7):4612-20 |
Mthfd2 methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase (Synonyms: NMDMC) | |
Results | Reference |
1* | J:159942 Pike ST, Rajendra R, Artzt K, Appling DR, Mitochondrial C1-tetrahydrofolate synthase (MTHFD1L) supports the flow of mitochondrial one-carbon units into the methyl cycle in embryos. J Biol Chem. 2010 Feb 12;285(7):4612-20 |
Mtmr2 myotubularin related protein 2 (Synonyms: 6030445P13Rik) | |
Results | Reference |
1* | J:354383 Berger P, Bonneick S, Willi S, Wymann M, Suter U, Loss of phosphatase activity in myotubularin-related protein 2 is associated with Charcot-Marie-Tooth disease type 4B1. Hum Mol Genet. 2002 Jun 15;11(13):1569-79 |
Mtor mechanistic target of rapamycin kinase (Synonyms: 2610315D21Rik, FKBP-rapamycin-associated protein FRAP, flat, Frap1, mechanistic target of rapamycin (serine/threonine kinase), RAFT1, RAPT1) | |
Results | Reference |
1 | J:235665 He S, Limi S, McGreal RS, Xie Q, Brennan LA, Kantorow WL, Kokavec J, Majumdar R, Hou H Jr, Edelmann W, Liu W, Ashery-Padan R, Zavadil J, Kantorow M, Skoultchi AI, Stopka T, Cvekl A, Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation. Development. 2016 Jun 1;143(11):1937-47 |
1 | J:312817 Lei X, Jiao J, UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling. Stem Cell Reports. 2018 Apr 10;10(4):1193-1207 |
1 | J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410 |
1 | J:171254 Matsumoto A, Onoyama I, Sunabori T, Kageyama R, Okano H, Nakayama KI, Fbxw7-dependent Degradation of Notch Is Required for Control of 'Stemness' and Neuronal-Glial Differentiation in Neural Stem Cells. J Biol Chem. 2011 Apr 15;286(15):13754-64 |
1 | J:346063 Rehmani T, Dias AP, Kamal M, Salih M, Tuana BS, Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway. Int J Mol Sci. 2024 Mar 1;25(5) |
1* | J:356303 Zhao Y, Zheng D, Cvekl A, A comprehensive spatial-temporal transcriptomic analysis of differentiating nascent mouse lens epithelial and fiber cells. Exp Eye Res. 2018 Oct;175:56-72 |
Mtss1 MTSS I-BAR domain containing 1 (Synonyms: 2310003N14Rik, D130001D01Rik, MGC:37896, MIM, mKIAA0429) | |
Results | Reference |
1 | J:349009 Kim N, Li Y, Yu R, Kwon HS, Song A, Jun MH, Jeong JY, Lee JH, Lim HH, Kim MJ, Kim JW, Oh WJ, Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1. Elife. 2024 Mar 25;13 |
1 | J:158762 Xia S, Li X, Johnson T, Seidel C, Wallace DP, Li R, Polycystin-dependent fluid flow sensing targets histone deacetylase 5 to prevent the development of renal cysts. Development. 2010 Apr;137(7):1075-84 |
Mttp microsomal triglyceride transfer protein (Synonyms: 1810043K16Rik, MTP) | |
Results | Reference |
1* | J:61562 Shelton JM, Lee MH, Richardson JA, Patel SB, Microsomal triglyceride transfer protein expression during mouse development. J Lipid Res. 2000 Apr;41(4):532-7 |
Muc1 mucin 1, transmembrane (Synonyms: CD227, EMA, Muc-1) | |
Results | Reference |
1 | J:270954 Bankaitis ED, Bechard ME, Gu G, Magnuson MA, Wright CVE, ROCK-nmMyoII, Notch and Neurog3 gene-dosage link epithelial morphogenesis with cell fate in the pancreatic endocrine-progenitor niche. Development. 2018 Sep 21;145(18):dev162115 |
1 | J:226612 Bankaitis ED, Bechard ME, Wright CV, Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche. Genes Dev. 2015 Oct 15;29(20):2203-16 |
2* | J:1362 Braga VM, Pemberton LF, Duhig T, Gendler SJ, Spatial and temporal expression of an epithelial mucin, Muc-1, during mouse development. Development. 1992 Jun;115(2):427-37 |
1 | J:331471 Brownfield DG, de Arce AD, Ghelfi E, Gillich A, Desai TJ, Krasnow MA, Alveolar cell fate selection and lifelong maintenance of AT2 cells by FGF signaling. Nat Commun. 2022 Nov 21;13(1):7137 |
1 | J:346123 Darrigrand JF, Salowka A, Torres-Cano A, Tapia-Rojo R, Zhu T, Garcia-Manyes S, Spagnoli FM, Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner. Dev Cell. 2024 Feb 5;59(3):326-338.e5 |
1 | J:220324 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C, Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 1;142(5):871-82 |
1 | J:141158 Fontaniere S, Duvillie B, Scharfmann R, Carreira C, Wang ZQ, Zhang CX, Tumour suppressor menin is essential for development of the pancreatic endocrine cells. J Endocrinol. 2008 Nov;199(2):287-98 |
1 | J:192856 George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE, Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol. 2012 Dec;32(24):5116-28 |
1 | J:219824 Hendley AM, Provost E, Bailey JM, Wang YJ, Cleveland MH, Blake D, Bittman RW, Roeser JC, Maitra A, Reynolds AB, Leach SD, p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas. Dev Biol. 2015 Mar 1;399(1):41-53 |
1 | J:284168 Nyeng P, Heilmann S, Lof-Ohlin ZM, Pettersson NF, Hermann FM, Reynolds AB, Semb H, p120ctn-Mediated Organ Patterning Precedes and Determines Pancreatic Progenitor Fate. Dev Cell. 2019 Apr 8;49(1):31-47.e9 |
1* | J:50062 Pepling ME, Spradling AC, Female mouse germ cells form synchronously dividing cysts. Development. 1998 Sep;125(17):3323-8 |
1 | J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356 |
1 | J:338071 Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn LJ, Rosenthal B, Gurtler M, Estanboulieh RR, Shvartsman D, Gifford DK, Trapnell C, Melton D, A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets. Cell. 2019 Feb 7;176(4):790-804.e13 |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
1 | J:364195 Yang L, Yu XX, Wang X, Jin CT, Xu CR, The expression order determines the pioneer functions of NGN3 and NEUROD1 in pancreatic endocrine differentiation. Sci Adv. 2025 Mar 28;11(13):eadt4770 |
Muc2 mucin 2 (Synonyms: 2010015E03Rik) | |
Results | Reference |
1 | J:291945 De Arcangelis A, Hamade H, Alpy F, Normand S, Bruyere E, Lefebvre O, Mechine-Neuville A, Siebert S, Pfister V, Lepage P, Laquerriere P, Dembele D, Delanoye-Crespin A, Rodius S, Robine S, Kedinger M, Van Seuningen I, Simon-Assmann P, Chamaillard M, Labouesse M, Georges-Labouesse E, Hemidesmosome integrity protects the colon against colitis and colorectal cancer. Gut. 2017 Oct;66(10):1748-1760 |
1 | J:283354 Guiu J, Hannezo E, Yui S, Demharter S, Ulyanchenko S, Maimets M, Jorgensen A, Perlman S, Lundvall L, Mamsen LS, Larsen A, Olesen RH, Andersen CY, Thuesen LL, Hare KJ, Pers TH, Khodosevich K, Simons BD, Jensen KB, Tracing the origin of adult intestinal stem cells. Nature. 2019 Jun;570(7759):107-111 |
1* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
Muc4 mucin 4 (Synonyms: 4933405I11Rik) | |
Results | Reference |
2 | J:356957 Rogers RL, Van Seuningen I, Gould J, Hertzog PJ, Naylor MJ, Pritchard MA, Transcript profiling of Elf5+/- mammary glands during pregnancy identifies novel targets of Elf5. PLoS One. 2010 Oct 7;5(10):e13150 |
Muc5ac mucin 5, subtypes A and C, tracheobronchial/gastric (Synonyms: 2210005L13Rik, MGM) | |
Results | Reference |
1* | J:121517 Danielian PS, Bender Kim CF, Caron AM, Vasile E, Bronson RT, Lees JA, E2f4 is required for normal development of the airway epithelium. Dev Biol. 2007 May 15;305(2):564-76 |
2 | J:28082 Holmberg M, Leonardsson G, Ny T, The species-specific differences in the cAMP regulation of the tissue-type plasminogen activator gene between rat, mouse and human is caused by a one-nucleotide substitution in the cAMP-responsive element of the promoters. Eur J Biochem. 1995 Jul 15;231(2):466-74 |
2* | J:280280 Rutledge EA, Parvez RK, Short KM, Smyth IM, McMahon AP, Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease. Dev Biol. 2019 Oct 15;454(2):156-169 |
Muc16 mucin 16 (Synonyms: 1110008I14Rik, Gm21044, LOC385009) | |
Results | Reference |
1* | J:141839 Wang Y, Cheon DJ, Lu Z, Cunningham SL, Chen CM, Luo RZ, Xing D, Orsulic S, Bast RC Jr, Behringer RR, MUC16 expression during embryogenesis, in adult tissues, and ovarian cancer in the mouse. Differentiation. 2008 Dec;76(10):1081-92 |
Mucl2 mucin-like 2 (Synonyms: Spt-1, Spt1) | |
Results | Reference |
1 | J:341713 Aure MH, Symonds JM, Villapudua CU, Dodge JT, Werner S, Knosp WM, Hoffman MP, FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation. Nat Commun. 2023 Oct 14;14(1):6485 |
Musk muscle, skeletal, receptor tyrosine kinase (Synonyms: MDK4, Nsk1, Nsk2, Nsk3) | |
Results | Reference |
1* | J:35622 Besser J, Zahalka MA, Ullrich A, Exclusive expression of the receptor tyrosine kinase MDK4 in skeletal muscle and the decidua. Mech Dev. 1996 Sep;59(1):41-52 |
1 | J:126807 Hippenmeyer S, Huber RM, Ladle DR, Murphy K, Arber S, ETS transcription factor Erm controls subsynaptic gene expression in skeletal muscles. Neuron. 2007 Sep 6;55(5):726-40 |
1* | J:149227 Liu Y, Oppenheim RW, Sugiura Y, Lin W, Abnormal development of the neuromuscular junction in Nedd4-deficient mice. Dev Biol. 2009 Jun 1;330(1):153-66 |
Mvk mevalonate kinase (Synonyms: 2310010A05Rik) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
Mvp major vault protein (Synonyms: 2310009M24Rik, LRP, VAULT1) | |
Results | Reference |
1 | J:343325 Kretz PF, Wagner C, Mikhaleva A, Montillot C, Hugel S, Morella I, Kannan M, Fischer MC, Milhau M, Yalcin I, Brambilla R, Selloum M, Herault Y, Reymond A, Collins SC, Yalcin B, Dissecting the autism-associated 16p11.2 locus identifies multiple drivers in neuroanatomical phenotypes and unveils a male-specific role for the major vault protein. Genome Biol. 2023 Nov 15;24(1):261 |
Mx1 MX dynamin-like GTPase 1 (Synonyms: Mx, Mx-1, myxovirus (influenza) resistance 1 polypeptide) | |
Results | Reference |
1 | J:288683 Gacem N, Kavo A, Zerad L, Richard L, Mathis S, Kapur RP, Parisot M, Amiel J, Dufour S, de la Grange P, Pingault V, Vallat JM, Bondurand N, ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. Nat Commun. 2020 Jan 10;11(1):198 |
Mxi1 MAX interactor 1, dimerization protein (Synonyms: bHLHc11, Mad2) | |
Results | Reference |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Myb myeloblastosis oncogene (Synonyms: c-myb) | |
Results | Reference |
1* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
2* | J:30262 Sitzmann J, Noben-Trauth K, Klempnauer KH, Expression of mouse c-myb during embryonic development. Oncogene. 1995 Dec 7;11(11):2273-9 |
1 | J:178367 Slamon DJ, Cline MJ, Expression of cellular oncogenes during embryonic and fetal development of the mouse. Proc Natl Acad Sci U S A. 1984 Nov;81(22):7141-5 |
1* | J:285404 Ueda T, Yokota T, Okuzaki D, Uno Y, Mashimo T, Kubota Y, Sudo T, Ishibashi T, Shingai Y, Doi Y, Ozawa T, Nakai R, Tanimura A, Ichii M, Ezoe S, Shibayama H, Oritani K, Kanakura Y, Endothelial Cell-Selective Adhesion Molecule Contributes to the Development of Definitive Hematopoiesis in the Fetal Liver. Stem Cell Reports. 2019 Dec 10;13(6):992-1005 |
Mybl1 myeloblastosis oncogene-like 1 (Synonyms: A-myb, G1-419-6, repro9) | |
Results | Reference |
1* | J:30262 Sitzmann J, Noben-Trauth K, Klempnauer KH, Expression of mouse c-myb during embryonic development. Oncogene. 1995 Dec 7;11(11):2273-9 |
1* | J:22230 Trauth K, Mutschler B, Jenkins NA, Gilbert DJ, Copeland NG, Klempnauer KH, Mouse A-myb encodes a trans-activator and is expressed in mitotically active cells of the developing central nervous system, adult testis and B lymphocytes. EMBO J. 1994 Dec 15;13(24):5994-6005 |
Mybl2 myeloblastosis oncogene-like 2 (Synonyms: Bmyb, B-Myb) | |
Results | Reference |
2 | J:290729 Grundl M, Walz S, Hauf L, Schwab M, Werner KM, Spahr S, Schulte C, Maric HM, Ade CP, Gaubatz S, Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes. PLoS Genet. 2020 May;16(5):e1008818 |
2 | J:32898 Sitzmann J, Noben-Trauth K, Kamano H, Klempnauer KH, Expression of B-Myb during mouse embryogenesis. Oncogene. 1996 May 2;12(9):1889-94 |
Myc myelocytomatosis oncogene (Synonyms: bHLHe39, c-myc, Myc2, Niard, Nird) | |
Results | Reference |
1 | J:239479 Arora H, Boulberdaa M, Qureshi R, Bitirim V, Messadeq N, Dolle P, Nebigil CG, Prokineticin receptor 1 is required for mesenchymal-epithelial transition in kidney development. FASEB J. 2016 Aug;30(8):2733-40 |
1* | J:317552 Casey SC, Blumberg B, The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver. Mol Endocrinol. 2012 Jun;26(6):916-25 |
1 | J:356060 Chau KF, Shannon ML, Fame RM, Fonseca E, Mullan H, Johnson MB, Sendamarai AK, Springel MW, Laurent B, Lehtinen MK, Downregulation of ribosome biogenesis during early forebrain development. Elife. 2018 May 10;7 |
1 | J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134 |
1 | J:53715 Ess KC, Witte DP, Bascomb CP, Aronow BJ, Diverse developing mouse lineages exhibit high-level c-Myb expression in immature cells and loss of expression upon differentiation. Oncogene. 1999 Jan 28;18(4):1103-11 |
1* | J:66029 Gouble A, Morello D, Synchronous and regulated expression of two AU-binding proteins, AUF1 and HuR, throughout murine development. Oncogene. 2000 Nov 9;19(47):5377-84 |
1 | J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90 |
1* | J:35027 Hirning U, Schmid P, Schulz WA, Rettenberger G, Hameister H, A comparative analysis of N-myc and c-myc expression and cellular proliferation in mouse organogenesis. Mech Dev. 1991 Feb;33(2):119-25 |
1* | J:8078 Jakobovits A, Schwab M, Bishop JM, Martin GR, Expression of N-myc in teratocarcinoma stem cells and mouse embryos. Nature. 1985 Nov 14-20;318(6042):188-91 |
1 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
1 | J:167233 Lee YC, Chang CJ, Bali D, Chen YT, Yan YT, Glycogen-branching enzyme deficiency leads to abnormal cardiac development: novel insights into glycogen storage disease IV. Hum Mol Genet. 2011 Feb 1;20(3):455-65 |
1 | J:86441 Lin MH, Kopan R, Long-range, nonautonomous effects of activated Notch1 on tissue homeostasis in the nail. Dev Biol. 2003 Nov 15;263(2):343-59 |
1 | J:171254 Matsumoto A, Onoyama I, Sunabori T, Kageyama R, Okano H, Nakayama KI, Fbxw7-dependent Degradation of Notch Is Required for Control of 'Stemness' and Neuronal-Glial Differentiation in Neural Stem Cells. J Biol Chem. 2011 Apr 15;286(15):13754-64 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1 | J:100687 Mill P, Mo R, Hu MC, Dagnino L, Rosenblum ND, Hui CC, Shh controls epithelial proliferation via independent pathways that converge on N-Myc. Dev Cell. 2005 Aug;9(2):293-303 |
1* | J:182715 Monahan P, Himes AD, Parfieniuk A, Raetzman LT, p21, an important mediator of quiescence during pituitary tumor formation, is dispensable for normal pituitary development during embryogenesis. Mech Dev. 2012 Jan-Feb;128(11-12):640-52 |
1* | J:77927 Muto S, Aiba A, Saito Y, Nakao K, Nakamura K, Tomita K, Kitamura T, Kurabayashi M, Nagai R, Higashihara E, Harris PC, Katsuki M, Horie S, Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant. Hum Mol Genet. 2002 Jul 15;11(15):1731-42 |
1 | J:180141 Qin S, Liu M, Niu W, Zhang CL, Dysregulation of Kruppel-like factor 4 during brain development leads to hydrocephalus in mice. Proc Natl Acad Sci U S A. 2011 Dec 27;108(52):21117-21 |
1* | J:35026 Schmid P, Schulz WA, Hameister H, Dynamic expression pattern of the myc protooncogene in midgestation mouse embryos. Science. 1989 Jan 13;243(4888):226-9 |
1 | J:187998 Shung CY, Ota S, Zhou ZQ, Keene DR, Hurlin PJ, Disruption of a Sox9-beta-catenin circuit by mutant Fgfr3 in thanatophoric dysplasia type II. Hum Mol Genet. 2012 Nov 1;21(21):4628-44 |
1 | J:178367 Slamon DJ, Cline MJ, Expression of cellular oncogenes during embryonic and fetal development of the mouse. Proc Natl Acad Sci U S A. 1984 Nov;81(22):7141-5 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1 | J:172282 Zhou ZQ, Shung CY, Ota S, Akiyama H, Keene DR, Hurlin PJ, Sequential and coordinated actions of c-Myc and N-Myc control appendicular skeletal development. PLoS One. 2011;6(4):e18795 |
Mycn v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived (Synonyms: bHLHe37, N-myc, Nmyc, Nmyc-1, Nmyc1) | |
Results | Reference |
1 | J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82 |
1 | J:216295 Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC, FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. 2014 Nov 1;395(1):50-61 |
1* | J:35027 Hirning U, Schmid P, Schulz WA, Rettenberger G, Hameister H, A comparative analysis of N-myc and c-myc expression and cellular proliferation in mouse organogenesis. Mech Dev. 1991 Feb;33(2):119-25 |
1* | J:8078 Jakobovits A, Schwab M, Bishop JM, Martin GR, Expression of N-myc in teratocarcinoma stem cells and mouse embryos. Nature. 1985 Nov 14-20;318(6042):188-91 |
1 | J:330416 Li J, Xu J, Jiang H, Zhang T, Ramakrishnan A, Shen L, Xu PX, Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance. J Am Soc Nephrol. 2021 Nov;32(11):2815-2833 |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
1 | J:171254 Matsumoto A, Onoyama I, Sunabori T, Kageyama R, Okano H, Nakayama KI, Fbxw7-dependent Degradation of Notch Is Required for Control of 'Stemness' and Neuronal-Glial Differentiation in Neural Stem Cells. J Biol Chem. 2011 Apr 15;286(15):13754-64 |
1 | J:100687 Mill P, Mo R, Hu MC, Dagnino L, Rosenblum ND, Hui CC, Shh controls epithelial proliferation via independent pathways that converge on N-Myc. Dev Cell. 2005 Aug;9(2):293-303 |
1 | J:267889 Moon S, Im SK, Kim N, Youn H, Park UH, Kim JY, Kim AR, An SJ, Kim JH, Sun W, Hwang JT, Kim EJ, Um SJ, Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis. Cell Death Dis. 2018 Nov 2;9(11):1118 |
2 | J:67879 Mugrauer G, Alt FW, Ekblom P, N-myc proto-oncogene expression during organogenesis in the developing mouse as revealed by in situ hybridization. J Cell Biol. 1988 Oct;107(4):1325-35 |
2 | J:97215 Okubo T, Knoepfler PS, Eisenman RN, Hogan BL, Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation. Development. 2005 Mar;132(6):1363-74 |
1* | J:56022 Shimono A, Okuda T, Kondoh H, N-myc-dependent repression of ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant. Mech Dev. 1999 May;83(1-2):39-52 |
1 | J:99391 Shu W, Guttentag S, Wang Z, Andl T, Ballard P, Lu MM, Piccolo S, Birchmeier W, Whitsett JA, Millar SE, Morrisey EE, Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung. Dev Biol. 2005 Jul 1;283(1):226-39 |
2 | J:121421 Shu W, Lu MM, Zhang Y, Tucker PW, Zhou D, Morrisey EE, Foxp2 and Foxp1 cooperatively regulate lung and esophagus development. Development. 2007 May;134(10):1991-2000 |
1 | J:160518 Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, Jenkins RB, Tihan T, Vandenberg SR, James CD, Tanaka K, Taylor MD, Weiss WA, Chesler L, Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010 May 15;24(10):1059-72 |
1 | J:119908 Wells JM, Esni F, Boivin GP, Aronow BJ, Stuart W, Combs C, Sklenka A, Leach SD, Lowy AM, Wnt/beta-catenin signaling is required for development of the exocrine pancreas. BMC Dev Biol. 2007;7:4 |
Myd88 myeloid differentiation primary response gene 88 | |
Results | Reference |
1 | J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47 |
Myf5 myogenic factor 5 (Synonyms: B130010J22Rik, bHLHc2, Myf-5) | |
Results | Reference |
1 | J:175458 Bren-Mattison Y, Hausburg M, Olwin BB, Growth of limb muscle is dependent on skeletal-derived Indian hedgehog. Dev Biol. 2011 Aug 15;356(2):486-95 |
3 | J:196361 Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnani MG, Messina G, Cossu G, Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory. Dev Cell. 2013 Mar 25;24(6):586-99 |
1* | J:98918 Kassar-Duchossoy L, Giacone E, Gayraud-Morel B, Jory A, Gomes D, Tajbakhsh S, Pax3/Pax7 mark a novel population of primitive myogenic cells during development. Genes Dev. 2005 Jun 15;19(12):1426-31 |
1* | J:43635 Laurent A, Pinset C, Aurade F, Vidaud M, Montarras D, Expression of myotonic dystrophy protein kinase gene during in vivo and in vitro mouse myogenesis. Cell Mol Biol (Noisy-Le-Grand). 1997 Sep;43(6):881-8 |
1 | J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97 |
1 | J:129041 Potthoff MJ, Arnold MA, McAnally J, Richardson JA, Bassel-Duby R, Olson EN, Regulation of skeletal muscle sarcomere integrity and postnatal muscle function by Mef2c. Mol Cell Biol. 2007 Dec;27(23):8143-51 |
1 | J:67329 Sumiyoshi H, Laub F, Yoshioka H, Ramirez F, Embryonic expression of type XIX collagen is transient and confined to muscle cells. Dev Dyn. 2001 Feb;220(2):155-62 |
1* | J:36716 Tajbakhsh S, Rocancourt D, Buckingham M, Muscle progenitor cells failing to respond to positional cues adopt non-myogenic fates in myf-5 null mice. Nature. 1996 Nov 21;384(6606):266-70 |
1 | J:168032 Zacharias AL, Lewandoski M, Rudnicki MA, Gage PJ, Pitx2 is an upstream activator of extraocular myogenesis and survival. Dev Biol. 2011 Jan 15;349(2):395-405 |
Myf6 myogenic factor 6 (Synonyms: bHLHc4, herculin, MRF4) | |
Results | Reference |
1* | J:43635 Laurent A, Pinset C, Aurade F, Vidaud M, Montarras D, Expression of myotonic dystrophy protein kinase gene during in vivo and in vitro mouse myogenesis. Cell Mol Biol (Noisy-Le-Grand). 1997 Sep;43(6):881-8 |
1 | J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97 |
2* | J:64537 Zhao W, Dhoot GK, Skeletal muscle precursors in mouse esophagus are determined during early fetal development. Dev Dyn. 2000 Sep;219(1):10-20 |
Myh1 myosin, heavy polypeptide 1, skeletal muscle, adult (Synonyms: A530084A17Rik, IId, IId/x, MyHC-IId/x, MYHC-IIX, Myhs-f, Myhs-f2, Myhsf2, myosin heavy chain 2X) | |
Results | Reference |
1 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1 | J:284333 Arai HN, Sato F, Yamamoto T, Woltjen K, Kiyonari H, Yoshimoto Y, Shukunami C, Akiyama H, Kist R, Sehara-Fujisawa A, Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate. Cell Rep. 2019 Oct 15;29(3):603-616.e5 |
1* | J:302851 Greschik H, Duteil D, Messaddeq N, Willmann D, Arrigoni L, Sum M, Jung M, Metzger D, Manke T, Gunther T, Schule R, The histone code reader Spin1 controls skeletal muscle development. Cell Death Dis. 2017 Nov 23;8(11):e3173 |
1 | J:224077 Huang AH, Riordan TJ, Pryce B, Weibel JL, Watson SS, Long F, Lefebvre V, Harfe BD, Stadler HS, Akiyama H, Tufa SF, Keene DR, Schweitzer R, Musculoskeletal integration at the wrist underlies the modular development of limb tendons. Development. 2015 Jul 15;142(14):2431-41 |
1 | J:220322 Kutchuk L, Laitala A, Soueid-Bomgarten S, Shentzer P, Rosendahl AH, Eilot S, Grossman M, Sagi I, Sormunen R, Myllyharju J, Maki JM, Hasson P, Muscle composition is regulated by a Lox-TGFbeta feedback loop. Development. 2015 Mar 1;142(5):983-93 |
1 | J:333369 Lipp SN, Jacobson KR, Colling HA, Tuttle TG, Miles DT, McCreery KP, Calve S, Mechanical loading is required for initiation of extracellular matrix deposition at the developing murine myotendinous junction. Matrix Biol. 2023 Feb;116:28-48 |
1 | J:58904 Lu BD, Allen DL, Leinwand LA, Lyons GE, Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development. Dev Biol. 1999 Dec 1;216(1):312-26 |
1* | J:61155 Valdez MR, Richardson JA, Klein WH, Olson EN, Failure of Myf5 to support myogenic differentiation without myogenin, MyoD, and MRF4. Dev Biol. 2000 Mar 15;219(2):287-98 |
2 | J:307861 Yaseen W, Kraft-Sheleg O, Zaffryar-Eilot S, Melamed S, Sun C, Millay DP, Hasson P, Fibroblast fusion to the muscle fiber regulates myotendinous junction formation. Nat Commun. 2021 Jun 22;12(1):3852 |
Myh2 myosin, heavy polypeptide 2, skeletal muscle, adult (Synonyms: MHC2A, MyHC-IIa, Myhs-f, Myhs-f1, Myhsf1) | |
Results | Reference |
1* | J:302851 Greschik H, Duteil D, Messaddeq N, Willmann D, Arrigoni L, Sum M, Jung M, Metzger D, Manke T, Gunther T, Schule R, The histone code reader Spin1 controls skeletal muscle development. Cell Death Dis. 2017 Nov 23;8(11):e3173 |
1* | J:100572 Hagiwara N, Ma B, Ly A, Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H. Dev Dyn. 2005 Oct;234(2):301-11 |
1 | J:224077 Huang AH, Riordan TJ, Pryce B, Weibel JL, Watson SS, Long F, Lefebvre V, Harfe BD, Stadler HS, Akiyama H, Tufa SF, Keene DR, Schweitzer R, Musculoskeletal integration at the wrist underlies the modular development of limb tendons. Development. 2015 Jul 15;142(14):2431-41 |
1 | J:60987 Kablar B, Tajbakhsh S, Rudnicki MA, Transdifferentiation of esophageal smooth to skeletal muscle is myogenic bHLH factor-dependent. Development. 2000 Apr;127(8):1627-39 |
1 | J:58904 Lu BD, Allen DL, Leinwand LA, Lyons GE, Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development. Dev Biol. 1999 Dec 1;216(1):312-26 |
1* | J:61155 Valdez MR, Richardson JA, Klein WH, Olson EN, Failure of Myf5 to support myogenic differentiation without myogenin, MyoD, and MRF4. Dev Biol. 2000 Mar 15;219(2):287-98 |
1 | J:103000 Watanabe R, Chano T, Inoue H, Isono T, Koiwai O, Okabe H, Rb1cc1 is critical for myoblast differentiation through Rb1 regulation. Virchows Arch. 2005 Sep;447(3):643-8 |
Myh3 myosin, heavy polypeptide 3, skeletal muscle, embryonic (Synonyms: MyHC-emb, Myhs-e, Myhse) | |
Results | Reference |
1 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1* | J:216142 Amann R, Wyder S, Slavotinek AM, Trueb B, The FgfrL1 receptor is required for development of slow muscle fibers. Dev Biol. 2014 Oct 15;394(2):228-41 |
1 | J:158726 Campos Y, Qiu X, Zanoteli E, Moshiach S, Vergani N, Bongiovanni A, Harris AJ, d'Azzo A, Ozz-E3 ubiquitin ligase targets sarcomeric embryonic myosin heavy chain during muscle development. PLoS One. 2010;5(3):e9866 |
1* | J:100572 Hagiwara N, Ma B, Ly A, Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H. Dev Dyn. 2005 Oct;234(2):301-11 |
1 | J:326543 Jiang A, Guo H, Jiang X, Tao J, Wu W, Liu H, G6PD Deficiency Is Crucial for Insulin Signaling Activation in Skeletal Muscle. Int J Mol Sci. 2022 Jul 4;23(13) |
1 | J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97 |
1* | J:48809 Rawls A, Valdez MR, Zhang W, Richardson J, Klein WH, Olson EN, Overlapping functions of the myogenic bHLH genes MRF4 and MyoD revealed in double mutant mice. Development. 1998 Jul;125(13):2349-58 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Myh4 myosin, heavy polypeptide 4, skeletal muscle (Synonyms: MHC2B, Minimsc, Minmus, MM, MYH-2B, MyHC-IIb, Myhsf) | |
Results | Reference |
1* | J:267598 Castiglioni I, Caccia R, Garcia-Manteiga JM, Ferri G, Caretti G, Molineris I, Nishioka K, Gabellini D, The Trithorax protein Ash1L promotes myoblast fusion by activating Cdon expression. Nat Commun. 2018 Nov 28;9(1):5026 |
1* | J:302851 Greschik H, Duteil D, Messaddeq N, Willmann D, Arrigoni L, Sum M, Jung M, Metzger D, Manke T, Gunther T, Schule R, The histone code reader Spin1 controls skeletal muscle development. Cell Death Dis. 2017 Nov 23;8(11):e3173 |
1* | J:100572 Hagiwara N, Ma B, Ly A, Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H. Dev Dyn. 2005 Oct;234(2):301-11 |
1 | J:58904 Lu BD, Allen DL, Leinwand LA, Lyons GE, Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development. Dev Biol. 1999 Dec 1;216(1):312-26 |
Myh6 myosin, heavy polypeptide 6, cardiac muscle, alpha (Synonyms: A830009F23Rik, alpha cardiac MHC, alpha-MHC, alphaMHC, alpha myosin, cardiomyopathy, hypertrophic 1, Myhc-a, Myhca) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
1* | J:152696 Callis TE, Pandya K, Seok HY, Tang RH, Tatsuguchi M, Huang ZP, Chen JF, Deng Z, Gunn B, Shumate J, Willis MS, Selzman CH, Wang DZ, MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest. 2009 Sep;119(9):2772-86 |
1* | J:179371 He A, Shen X, Ma Q, Cao J, von Gise A, Zhou P, Wang G, Marquez VE, Orkin SH, Pu WT, PRC2 directly methylates GATA4 and represses its transcriptional activity. Genes Dev. 2012 Jan 1;26(1):37-42 |
1 | J:263273 Ng WA, Grupp IL, Subramaniam A, Robbins J, Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart. Circ Res. 1991 Jun;68(6):1742-50 |
1* | J:316724 Pedernera E, Gomora MJ, Meneses I, De Ita M, Mendez C, Androgen receptor is expressed in mouse cardiomyocytes at prenatal and early postnatal developmental stages. BMC Physiol. 2017 Aug 14;17(1):7 |
1 | J:253740 Yan J, Zhang L, Sultana N, Oh JG, Wu B, Hajjar RJ, Zhou B, Cai CL, A series of robust genetic indicators for definitive identification of cardiomyocytes. J Mol Cell Cardiol. 2016 Aug;97:278-85 |
2* | J:59238 Zammit PS, Kelly RG, Franco D, Brown N, Moorman AF, Buckingham ME, Suppression of atrial myosin gene expression occurs independently in the left and right ventricles of the developing mouse heart. Dev Dyn. 2000 Jan;217(1):75-85 |
Myh7 myosin, heavy polypeptide 7, cardiac muscle, beta (Synonyms: beta-MHC, betaMHC, B-MHC, MYH-beta/slow, Myhc-b, Myhcb, MyHC-I) | |
Results | Reference |
1 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1* | J:216142 Amann R, Wyder S, Slavotinek AM, Trueb B, The FgfrL1 receptor is required for development of slow muscle fibers. Dev Biol. 2014 Oct 15;394(2):228-41 |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
1* | J:152696 Callis TE, Pandya K, Seok HY, Tang RH, Tatsuguchi M, Huang ZP, Chen JF, Deng Z, Gunn B, Shumate J, Willis MS, Selzman CH, Wang DZ, MicroRNA-208a is a regulator of cardiac hypertrophy and conduction in mice. J Clin Invest. 2009 Sep;119(9):2772-86 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:225351 Gopalakrishnan S, Comai G, Sambasivan R, Francou A, Kelly RG, Tajbakhsh S, A Cranial Mesoderm Origin for Esophagus Striated Muscles. Dev Cell. 2015 Sep 28;34(6):694-704 |
1* | J:100572 Hagiwara N, Ma B, Ly A, Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H. Dev Dyn. 2005 Oct;234(2):301-11 |
1 | J:58904 Lu BD, Allen DL, Leinwand LA, Lyons GE, Spatial and temporal changes in myosin heavy chain gene expression in skeletal muscle development. Dev Biol. 1999 Dec 1;216(1):312-26 |
1 | J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97 |
1 | J:263273 Ng WA, Grupp IL, Subramaniam A, Robbins J, Cardiac myosin heavy chain mRNA expression and myocardial function in the mouse heart. Circ Res. 1991 Jun;68(6):1742-50 |
1* | J:316724 Pedernera E, Gomora MJ, Meneses I, De Ita M, Mendez C, Androgen receptor is expressed in mouse cardiomyocytes at prenatal and early postnatal developmental stages. BMC Physiol. 2017 Aug 14;17(1):7 |
1 | J:241609 Taglietti V, Maroli G, Cermenati S, Monteverde S, Ferrante A, Rossi G, Cossu G, Beltrame M, Messina G, Nfix Induces a Switch in Sox6 Transcriptional Activity to Regulate MyHC-I Expression in Fetal Muscle. Cell Rep. 2016 Nov 22;17(9):2354-2366 |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
1 | J:326460 Yang R, Li R, Huang Z, Zuo Y, Yue H, Wu H, Gu F, Wang F, He M, Bian Z, Mycn deficiency underlies the development of orofacial clefts in mice and humans. Hum Mol Genet. 2022 Mar 3;31(5):803-815 |
Myh8 myosin, heavy polypeptide 8, skeletal muscle, perinatal (Synonyms: 4832426G23Rik, MyHC-pn, Myhs-p, Myhsp) | |
Results | Reference |
1* | J:100572 Hagiwara N, Ma B, Ly A, Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H. Dev Dyn. 2005 Oct;234(2):301-11 |
1 | J:60987 Kablar B, Tajbakhsh S, Rudnicki MA, Transdifferentiation of esophageal smooth to skeletal muscle is myogenic bHLH factor-dependent. Development. 2000 Apr;127(8):1627-39 |
1 | J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97 |
Myh9 myosin, heavy polypeptide 9, non-muscle (Synonyms: D0Jmb2, E030044M24Rik, Fltn, Myhn-1, Myhn1, myosin IIA, NMHC II-A) | |
Results | Reference |
1 | J:278104 Acebedo AR, Suzuki K, Hino S, Alcantara MC, Sato Y, Haga H, Matsumoto KI, Nakao M, Shimamura K, Takeo T, Nakagata N, Miyagawa S, Nishinakamura R, Adelstein RS, Yamada G, Mesenchymal actomyosin contractility is required for androgen-driven urethral masculinization in mice. Commun Biol. 2019;2:95 |
1 | J:90427 Golomb E, Ma X, Jana SS, Preston YA, Kawamoto S, Shoham NG, Goldin E, Conti MA, Sellers JR, Adelstein RS, Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J Biol Chem. 2004 Jan 23;279(4):2800-8 |
2 | J:199510 Lee J, Andreeva A, Sipe CW, Liu L, Cheng A, Lu X, PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium. Curr Biol. 2012 Jun 5;22(11):956-66 |
2 | J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134 |
1 | J:92081 Ma X, Kawamoto S, Hara Y, Adelstein RS, A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons. Mol Biol Cell. 2004 Jun;15(6):2568-79 |
2 | J:91334 Mhatre AN, Li J, Kim Y, Coling DE, Lalwani AK, Cloning and developmental expression of nonmuscle myosin IIA (Myh9) in the mammalian inner ear. J Neurosci Res. 2004 May 1;76(3):296-305 |
3 | J:149532 Yamamoto N, Okano T, Ma X, Adelstein RS, Kelley MW, Myosin II regulates extension, growth and patterning in the mammalian cochlear duct. Development. 2009 Jun;136(12):1977-86 |
Myh10 myosin, heavy polypeptide 10, non-muscle (Synonyms: 5730504C04Rik, 9330167F11Rik, Fltn, Fltn, mKIAA3005, Myhn-2, Myhn2, myosin IIB, Myosin IIB, NMHC-B, NMHC II-B, nonmuscle myosin heavy chain II-B, nonmuscle myosin heavy chain IIB, SMemb) | |
Results | Reference |
1 | J:278104 Acebedo AR, Suzuki K, Hino S, Alcantara MC, Sato Y, Haga H, Matsumoto KI, Nakao M, Shimamura K, Takeo T, Nakagata N, Miyagawa S, Nishinakamura R, Adelstein RS, Yamada G, Mesenchymal actomyosin contractility is required for androgen-driven urethral masculinization in mice. Commun Biol. 2019;2:95 |
1 | J:90427 Golomb E, Ma X, Jana SS, Preston YA, Kawamoto S, Shoham NG, Goldin E, Conti MA, Sellers JR, Adelstein RS, Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J Biol Chem. 2004 Jan 23;279(4):2800-8 |
1* | J:283394 Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S, Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162 |
2 | J:199510 Lee J, Andreeva A, Sipe CW, Liu L, Cheng A, Lu X, PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium. Curr Biol. 2012 Jun 5;22(11):956-66 |
2 | J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134 |
1 | J:92081 Ma X, Kawamoto S, Hara Y, Adelstein RS, A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons. Mol Biol Cell. 2004 Jun;15(6):2568-79 |
1 | J:112536 Ma X, Kawamoto S, Uribe J, Adelstein RS, Function of the neuron-specific alternatively spliced isoforms of nonmuscle myosin II-B during mouse brain development. Mol Biol Cell. 2006 May;17(5):2138-49 |
1 | J:248868 Ridge LA, Mitchell K, Al-Anbaki A, Shaikh Qureshi WM, Stephen LA, Tenin G, Lu Y, Lupu IE, Clowes C, Robertson A, Barnes E, Wright JA, Keavney B, Ehler E, Lovell SC, Kadler KE, Hentges KE, Non-muscle myosin IIB (Myh10) is required for epicardial function and coronary vessel formation during mammalian development. PLoS Genet. 2017 Oct;13(10):e1007068 |
3 | J:149532 Yamamoto N, Okano T, Ma X, Adelstein RS, Kelley MW, Myosin II regulates extension, growth and patterning in the mammalian cochlear duct. Development. 2009 Jun;136(12):1977-86 |
Myh11 myosin, heavy polypeptide 11, smooth muscle (Synonyms: SM1, SM2, smMHC) | |
Results | Reference |
1 | J:166547 Airik R, Trowe MO, Foik A, Farin HF, Petry M, Schuster-Gossler K, Schweizer M, Scherer G, Kist R, Kispert A, Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme. Hum Mol Genet. 2010 Dec 15;19(24):4918-29 |
1* | J:272619 Aydogdu N, Rudat C, Trowe MO, Kaiser M, Ludtke TH, Taketo MM, Christoffels VM, Moon A, Kispert A, TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827 |
1 | J:244068 Bohnenpoll T, Wittern AB, Mamo TM, Weiss AC, Rudat C, Kleppa MJ, Schuster-Gossler K, Wojahn I, Ludtke TH, Trowe MO, Kispert A, A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development. PLoS Genet. 2017 Aug;13(8):e1006951 |
1 | J:68046 Demolombe S, Franco D, de Boer P, Kuperschmidt S, Roden D, Pereon Y, Jarry A, Moorman AF, Escande D, Differential expression of KvLQT1 and its regulator IsK in mouse epithelia. Am J Physiol Cell Physiol. 2001 Feb;280(2):C359-72 |
1 | J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767 |
1 | J:228882 Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS, Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016 Jan 1;409(1):218-33 |
1 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:170883 Huang J, Davis EC, Chapman SL, Budatha M, Marmorstein LY, Word RA, Yanagisawa H, Fibulin-4 deficiency results in ascending aortic aneurysms: a potential link between abnormal smooth muscle cell phenotype and aneurysm progression. Circ Res. 2010 Feb 19;106(3):583-92 |
1 | J:146619 Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong TT, Shaw RM, Srivastava D, Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell. 2009 Feb;16(2):233-44 |
1 | J:254094 Jing X, Gao Y, Xiao S, Qin Q, Wei X, Yan Y, Wu L, Deng S, Du J, Liu Y, She Q, Hypoxia induced the differentiation of Tbx18-positive epicardial cells to CoSMCs. Sci Rep. 2016 Jul 26;6:30468 |
1 | J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:326547 Lu P, Wang P, Wu B, Wang Y, Liu Y, Cheng W, Feng X, Yuan X, Atteya MM, Ferro H, Sugi Y, Rydquist G, Esmaily M, Butcher JT, Chang CP, Lenz J, Zheng D, Zhou B, A SOX17-PDGFB signaling axis regulates aortic root development. Nat Commun. 2022 Jul 13;13(1):4065 |
1 | J:243772 Mamo TM, Wittern AB, Kleppa MJ, Bohnenpoll T, Weiss AC, Kispert A, BMP4 uses several different effector pathways to regulate proliferation and differentiation in the epithelial and mesenchymal tissue compartments of the developing mouse ureter. Hum Mol Genet. 2017 Sep 15;26(18):3553-3563 |
1 | J:202129 Martin E, Caubit X, Airik R, Vola C, Fatmi A, Kispert A, Fasano L, TSHZ3 and SOX9 regulate the timing of smooth muscle cell differentiation in the ureter by reducing myocardin activity. PLoS One. 2013;8(5):e63721 |
1 | J:21547 Miano JM, Cserjesi P, Ligon KL, Periasamy M, Olson EN, Smooth muscle myosin heavy chain exclusively marks the smooth muscle lineage during mouse embryogenesis. Circ Res. 1994 Nov;75(5):803-12 |
1* | J:319644 Ruan J, Zhang L, Hu D, Qu X, Yang F, Chen F, He X, Shen J, Dong K, Sweet M, Sanchez C, Li D, Shou W, Zhou J, Cai CL, Novel Myh11 Dual Reporter Mouse Model Provides Definitive Labeling and Identification of Smooth Muscle Cells-Brief Report. Arterioscler Thromb Vasc Biol. 2021 Feb;41(2):815-821 |
1 | J:188834 Shen D, Li J, Lepore JJ, Anderson TJ, Sinha S, Lin AY, Cheng L, Cohen ED, Roberts JD Jr, Dedhar S, Parmacek MS, Gerszten RE, Aortic aneurysm generation in mice with targeted deletion of integrin-linked kinase in vascular smooth muscle cells. Circ Res. 2011 Sep 2;109(6):616-28 |
1 | J:229606 Volz KS, Jacobs AH, Chen HI, Poduri A, McKay AS, Riordan DP, Kofler N, Kitajewski J, Weissman I, Red-Horse K, Pericytes are progenitors for coronary artery smooth muscle. Elife. 2015;4:e10036 |
2 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:193198 Wu B, Zhang Z, Lui W, Chen X, Wang Y, Chamberlain AA, Moreno-Rodriguez RA, Markwald RR, O'Rourke BP, Sharp DJ, Zheng D, Lenz J, Baldwin HS, Chang CP, Zhou B, Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling. Cell. 2012 Nov 21;151(5):1083-96 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
Myh14 myosin, heavy polypeptide 14 (Synonyms: 2400004E04Rik, NMHC II-C) | |
Results | Reference |
1 | J:90427 Golomb E, Ma X, Jana SS, Preston YA, Kawamoto S, Shoham NG, Goldin E, Conti MA, Sellers JR, Adelstein RS, Identification and characterization of nonmuscle myosin II-C, a new member of the myosin II family. J Biol Chem. 2004 Jan 23;279(4):2800-8 |
1* | J:149772 Jana SS, Kim KY, Mao J, Kawamoto S, Sellers JR, Adelstein RS, An alternatively spliced isoform of non-muscle myosin II-C is not regulated by myosin light chain phosphorylation. J Biol Chem. 2009 Apr 24;284(17):11563-71 |
2 | J:199510 Lee J, Andreeva A, Sipe CW, Liu L, Cheng A, Lu X, PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium. Curr Biol. 2012 Jun 5;22(11):956-66 |
1 | J:92081 Ma X, Kawamoto S, Hara Y, Adelstein RS, A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons. Mol Biol Cell. 2004 Jun;15(6):2568-79 |
3 | J:149532 Yamamoto N, Okano T, Ma X, Adelstein RS, Kelley MW, Myosin II regulates extension, growth and patterning in the mammalian cochlear duct. Development. 2009 Jun;136(12):1977-86 |
Myhc myosin heavy chain, cardiac muscle complex | |
Results | Reference |
3 | J:196361 Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnani MG, Messina G, Cossu G, Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory. Dev Cell. 2013 Mar 25;24(6):586-99 |
1 | J:131962 Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ, Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2111-6 |
1 | J:225351 Gopalakrishnan S, Comai G, Sambasivan R, Francou A, Kelly RG, Tajbakhsh S, A Cranial Mesoderm Origin for Esophagus Striated Muscles. Dev Cell. 2015 Sep 28;34(6):694-704 |
1 | J:150129 Harel I, Nathan E, Tirosh-Finkel L, Zigdon H, Guimaraes-Camboa N, Evans SM, Tzahor E, Distinct origins and genetic programs of head muscle satellite cells. Dev Cell. 2009 Jun;16(6):822-32 |
1 | J:204000 Wood WM, Etemad S, Yamamoto M, Goldhamer DJ, MyoD-expressing progenitors are essential for skeletal myogenesis and satellite cell development. Dev Biol. 2013 Dec 1;384(1):114-27 |
Myl1 myosin, light polypeptide 1 (Synonyms: MLC1f, MLC3f, Mylf) | |
Results | Reference |
1* | J:329933 Akkuratova N, Faure L, Kameneva P, Kastriti ME, Adameyko I, Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics. Front Endocrinol (Lausanne). 2022;13:1020000 |
1* | J:34383 McGrew MJ, Bogdanova N, Hasegawa K, Hughes SH, Kitsis RN, Rosenthal N, Distinct gene expression patterns in skeletal and cardiac muscle are dependent on common regulatory sequences in the MLC1/3 locus. Mol Cell Biol. 1996 Aug;16(8):4524-34 |
1 | J:130500 Zammit PS, Cohen A, Buckingham ME, Kelly RG, Integration of embryonic and fetal skeletal myogenic programs at the myosin light chain 1f/3f locus. Dev Biol. 2008 Jan 1;313(1):420-33 |
Myl2 myosin, light polypeptide 2, regulatory, cardiac, slow (Synonyms: Gm32672, MLC-2, Mlc2v, MLC-2v, Mylpc) | |
Results | Reference |
1* | J:268201 Zhang Z, Nam YJ, Generation of MLC-2v-tdTomato knock-in reporter mouse line. Genesis. 2018 Oct;56(10):e23256 |
Myl4 myosin, light polypeptide 4 (Synonyms: ELC, ELC1a, MLC1a, Myla) | |
Results | Reference |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1* | J:59238 Zammit PS, Kelly RG, Franco D, Brown N, Moorman AF, Buckingham ME, Suppression of atrial myosin gene expression occurs independently in the left and right ventricles of the developing mouse heart. Dev Dyn. 2000 Jan;217(1):75-85 |
Myl7 myosin, light polypeptide 7, regulatory (Synonyms: MLC2a, MLC-2alpha, Mylc2a, RLC-A) | |
Results | Reference |
1 | J:173586 Hahurij ND, Kolditz DP, Bokenkamp R, Markwald RR, Schalij MJ, Poelmann RE, Gittenberger-DE Groot AC, Blom NA, Accessory atrioventricular myocardial pathways in mouse heart development: substrate for supraventricular tachycardias. Pediatr Res. 2011 Jul;70(1):37-43 |
1 | J:192707 He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, Pu WT, Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res. 2012 Feb 3;110(3):406-15 |
Myl9 myosin, light polypeptide 9, regulatory (Synonyms: MLC20, Mylc2c, RLC-C) | |
Results | Reference |
1 | J:278104 Acebedo AR, Suzuki K, Hino S, Alcantara MC, Sato Y, Haga H, Matsumoto KI, Nakao M, Shimamura K, Takeo T, Nakagata N, Miyagawa S, Nishinakamura R, Adelstein RS, Yamada G, Mesenchymal actomyosin contractility is required for androgen-driven urethral masculinization in mice. Commun Biol. 2019;2:95 |
1 | J:331894 Alcantara MC, Suzuki K, Acebedo AR, Kajioka D, Hirohata S, Kaisho T, Hatano Y, Yamagata K, Takahashi S, Yamada G, Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice. iScience. 2022 Dec 22;25(12):105609 |
1 | J:266265 Kishimoto K, Tamura M, Nishita M, Minami Y, Yamaoka A, Abe T, Shigeta M, Morimoto M, Synchronized mesenchymal cell polarization and differentiation shape the formation of the murine trachea and esophagus. Nat Commun. 2018 Jul 19;9(1):2816 |
1 | J:294113 Lough KJ, Byrd KM, Descovich CP, Spitzer DC, Bergman AJ, Beaudoin GM 3rd, Reichardt LF, Williams SE, Telophase correction refines division orientation in stratified epithelia. Elife. 2019 Dec 13;8:e49249 |
1 | J:98250 Shimizu Y, Thumkeo D, Keel J, Ishizaki T, Oshima H, Oshima M, Noda Y, Matsumura F, Taketo MM, Narumiya S, ROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundles. J Cell Biol. 2005 Mar 14;168(6):941-53 |
Mylk myosin, light polypeptide kinase (Synonyms: 9530072E15Rik, A930019C19Rik, Mlck, MLCK108, MLCK210, nmMlck, telokin) | |
Results | Reference |
1* | J:68051 Herring BP, Lyons GE, Hoggatt AM, Gallagher PJ, Telokin expression is restricted to smooth muscle tissues during mouse development. Am J Physiol Cell Physiol. 2001 Jan;280(1):C12-21 |
1 | J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134 |
1 | J:202129 Martin E, Caubit X, Airik R, Vola C, Fatmi A, Kispert A, Fasano L, TSHZ3 and SOX9 regulate the timing of smooth muscle cell differentiation in the ureter by reducing myocardin activity. PLoS One. 2013;8(5):e63721 |
Mymk myomaker, myoblast fusion factor (Synonyms: 1110002H13Rik, Tmem8c) | |
Results | Reference |
1* | J:267598 Castiglioni I, Caccia R, Garcia-Manteiga JM, Ferri G, Caretti G, Molineris I, Nishioka K, Gabellini D, The Trithorax protein Ash1L promotes myoblast fusion by activating Cdon expression. Nat Commun. 2018 Nov 28;9(1):5026 |
Mymx myomixer, myoblast fusion factor (Synonyms: minion, myomerger) | |
Results | Reference |
1 | J:241565 Zhang Q, Vashisht AA, O'Rourke J, Corbel SY, Moran R, Romero A, Miraglia L, Zhang J, Durrant E, Schmedt C, Sampath SC, Sampath SC, The microprotein Minion controls cell fusion and muscle formation. Nat Commun. 2017 Jun 01;8:15664 |
Myo3a myosin IIIA (Synonyms: 9030416P08Rik) | |
Results | Reference |
1 | J:230827 Lelli A, Michel V, Boutet de Monvel J, Cortese M, Bosch-Grau M, Aghaie A, Perfettini I, Dupont T, Avan P, El-Amraoui A, Petit C, Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth. J Cell Biol. 2016 Jan 18;212(2):231-44 |
Myo3b myosin IIIB (Synonyms: A430065P19Rik) | |
Results | Reference |
1 | J:230827 Lelli A, Michel V, Boutet de Monvel J, Cortese M, Bosch-Grau M, Aghaie A, Perfettini I, Dupont T, Avan P, El-Amraoui A, Petit C, Class III myosins shape the auditory hair bundles by limiting microvilli and stereocilia growth. J Cell Biol. 2016 Jan 18;212(2):231-44 |
Myo5c myosin VC (Synonyms: 9130003O20Rik) | |
Results | Reference |
1* | J:325107 Cao X, Yan Y, Luo X, Yang X, Cui H, Yang Y, Li H, Analyses of the circadian clock genes expression in whole embryos and maternal major tissues of mice. J Mol Histol. 2022 Apr;53(2):473-482 |
Myo6 myosin VI
(Synonyms:
Myo6 | |
Results | Reference |
1 | J:199162 Cai T, Seymour ML, Zhang H, Pereira FA, Groves AK, Conditional deletion of Atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of Corti. J Neurosci. 2013 Jun 12;33(24):10110-22 |
1 | J:332313 Cantu-Guerra HL, Papazian MR, Gorsky AL, Alekos NS, Caccavano A, Karagulyan N, Neef J, Vicini S, Moser T, Coate TM, Cochlear hair cell innervation is dependent on a modulatory function of Semaphorin-3A. Dev Dyn. 2023 Jan;252(1):124-144 |
2 | J:226819 Coate TM, Spita NA, Zhang KD, Isgrig KT, Kelley MW, Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife. 2015;4 |
1 | J:139256 Driver EC, Pryor SP, Hill P, Turner J, Ruther U, Biesecker LG, Griffith AJ, Kelley MW, Hedgehog signaling regulates sensory cell formation and auditory function in mice and humans. J Neurosci. 2008 Jul 16;28(29):7350-8 |
1 | J:180774 Grimsley-Myers CM, Sipe CW, Wu DK, Lu X, Redundant functions of Rac GTPases in inner ear morphogenesis. Dev Biol. 2012 Feb 15;362(2):172-86 |
1* | J:263979 Harley RJ, Murdy JP, Wang Z, Kelly MC, Ropp TF, Park SH, Maness PF, Manis PB, Coate TM, Neuronal cell adhesion molecule (NrCAM) is expressed by sensory cells in the cochlea and is necessary for proper cochlear innervation and sensory domain patterning during development. Dev Dyn. 2018 Mar 14; |
1 | J:266597 Hartman BH, Bscke R, Ellwanger DC, Keymeulen S, Scheibinger M, Heller S, Fbxo2(VHC) mouse and embryonic stem cell reporter lines delineate in vitro-generated inner ear sensory epithelia cells and enable otic lineage selection and Cre-recombination. Dev Biol. 2018 Nov 1;443(1):64-77 |
1 | J:137155 Hayashi T, Ray CA, Bermingham-McDonogh O, Fgf20 is required for sensory epithelial specification in the developing cochlea. J Neurosci. 2008 Jun 4;28(23):5991-9 |
1 | J:184501 Huh SH, Jones J, Warchol ME, Ornitz DM, Differentiation of the lateral compartment of the cochlea requires a temporally restricted FGF20 signal. PLoS Biol. 2012 Jan;10(1):e1001231 |
1 | J:131308 Jones C, Roper VC, Foucher I, Qian D, Banizs B, Petit C, Yoder BK, Chen P, Ciliary proteins link basal body polarization to planar cell polarity regulation. Nat Genet. 2008 Jan;40(1):69-77 |
1 | J:279215 Jung JS, Zhang KD, Wang Z, McMurray M, Tkaczuk A, Ogawa Y, Hertzano R, Coate TM, Semaphorin-5B Controls Spiral Ganglion Neuron Branch Refinement during Development. J Neurosci. 2019 Aug 14;39(33):6425-6438 |
1 | J:251343 Kim YJ, Wang SZ, Tymanskyj S, Ma L, Tao HW, Zhang LI, Dcc Mediates Functional Assembly of Peripheral Auditory Circuits. Sci Rep. 2016 Apr 4;6:23799 |
1 | J:336865 Li S, He S, Lu Y, Jia S, Liu Z, Epistatic genetic interactions between Insm1 and Ikzf2 during cochlear outer hair cell development. Cell Rep. 2023 May 30;42(5):112504 |
1 | J:333396 Luo Z, Du Y, Li S, Zhang H, Shu M, Zhang D, He S, Wang G, Lu F, Liu Z, Three distinct Atoh1 enhancers cooperate for sound receptor hair cell development. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2119850119 |
1 | J:106101 Manji SS, Sorensen BS, Klockars T, Lam T, Hutchison W, Dahl HH, Molecular characterization and expression of maternally expressed gene 3 (Meg3/Gtl2) RNA in the mouse inner ear. J Neurosci Res. 2006 Feb 1;83(2):181-90 |
1 | J:98518 Mantela J, Jiang Z, Ylikoski J, Fritzsch B, Zacksenhaus E, Pirvola U, The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear. Development. 2005 May;132(10):2377-88 |
1 | J:91334 Mhatre AN, Li J, Kim Y, Coling DE, Lalwani AK, Cloning and developmental expression of nonmuscle myosin IIA (Myh9) in the mammalian inner ear. J Neurosci Res. 2004 May 1;76(3):296-305 |
1 | J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12) |
1* | J:178908 Okano T, Xuan S, Kelley MW, Insulin-like growth factor signaling regulates the timing of sensory cell differentiation in the mouse cochlea. J Neurosci. 2011 Dec 7;31(49):18104-18 |
1* | J:351381 Pan Y, Li S, He S, Wang G, Li C, Liu Z, Xiang M, Fgf8(P2A-3xGFP/+): A New Genetic Mouse Model for Specifically Labeling and Sorting Cochlear Inner Hair Cells. Neurosci Bull. 2023 Dec;39(12):1762-1774 |
1 | J:286655 Sakamoto S, Tateya T, Omori K, Kageyama R, Id genes are required for morphogenesis and cellular patterning in the developing mammalian cochlea. Dev Biol. 2020 Apr 15;460(2):164-175 |
1 | J:248731 Salehi P, Ge MX, Gundimeda U, Michelle Baum L, Lael Cantu H, Lavinsky J, Tao L, Myint A, Cruz C, Wang J, Nikolakopoulou AM, Abdala C, Kelley MW, Ohyama T, Coate TM, Friedman RA, Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea. PLoS Genet. 2017 Oct;13(10):e1007048 |
1 | J:204446 Tateya T, Imayoshi I, Tateya I, Hamaguchi K, Torii H, Ito J, Kageyama R, Hedgehog signaling regulates prosensory cell properties during the basal-to-apical wave of hair cell differentiation in the mammalian cochlea. Development. 2013 Sep;140(18):3848-57 |
1* | J:200791 Wakaoka T, Motohashi T, Hayashi H, Kuze B, Aoki M, Mizuta K, Kunisada T, Ito Y, Tracing Sox10-expressing cells elucidates the dynamic development of the mouse inner ear. Hear Res. 2013 Aug;302:17-25 |
1* | J:80025 Wallis D, Hamblen M, Zhou Y, Venken KJ, Schumacher A, Grimes HL, Zoghbi HY, Orkin SH, Bellen HJ, The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival. Development. 2003 Jan;130(1):221-32 |
1* | J:169193 Walsh T, Pierce SB, Lenz DR, Brownstein Z, Dagan-Rosenfeld O, Shahin H, Roeb W, McCarthy S, Nord AS, Gordon CR, Ben-Neriah Z, Sebat J, Kanaan M, Lee MK, Frydman M, King MC, Avraham KB, Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51. Am J Hum Genet. 2010 Jul 9;87(1):101-9 |
1 | J:199796 Wang SZ, Ibrahim LA, Kim YJ, Gibson DA, Leung HC, Yuan W, Zhang KK, Tao HW, Ma L, Zhang LI, Slit/Robo Signaling Mediates Spatial Positioning of Spiral Ganglion Neurons during Development of Cochlear Innervation. J Neurosci. 2013 Jul 24;33(30):12242-54 |
1 | J:302429 Wang Z, Jung JS, Inbar TC, Rangoussis KM, Faaborg-Andersen C, Coate TM, The Purinergic Receptor P2rx3 is Required for Spiral Ganglion Neuron Branch Refinement during Development. eNeuro. 2020 Jul/Aug;7(4):ENEURO.0179-20.2020 |
1* | J:43752 Xiang M, Gao WQ, Hasson T, Shin JJ, Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells. Development. 1998 Oct;125(20):3935-46 |
Myo7a myosin VIIA (Synonyms: Hdb, Myo7, nmf371, polka, USH1B) | |
Results | Reference |
1 | J:225514 Ahmed M, Ura K, Streit A, Auditory hair cell defects as potential cause for sensorineural deafness in Wolf-Hirschhorn syndrome. Dis Model Mech. 2015 Sep 1;8(9):1027-35 |
1* | J:149467 Bosman EA, Quint E, Fuchs H, Hrabe de Angelis M, Steel KP, Catweasel mice: a novel role for Six1 in sensory patch development and a model for branchio-oto-renal syndrome. Dev Biol. 2009 Apr 15;328(2):285-96 |
1 | J:83482 Chen P, Zindy F, Abdala C, Liu F, Li X, Roussel MF, Segil N, Progressive hearing loss in mice lacking the cyclin-dependent kinase inhibitor Ink4d. Nat Cell Biol. 2003 May;5(5):422-6 |
1 | J:166789 Dong Y, Sui L, Yamaguchi F, Kamitori K, Hirata Y, Hossain MA, Suzuki A, Holley MC, Tokuda M, Phosphatase and tensin homolog deleted on chromosome 10 regulates sensory cell proliferation and differentiation of hair bundles in the mammalian cochlea. Neuroscience. 2010 Nov 10;170(4):1304-13 |
2 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
1* | J:279271 Ellis K, Driver EC, Okano T, Lemons A, Kelley MW, GSK3 regulates hair cell fate in the developing mammalian cochlea. Dev Biol. 2019 Sep 15;453(2):191-205 |
1 | J:311887 Filova I, Dvorakova M, Bohuslavova R, Pavlinek A, Elliott KL, Vochyanova S, Fritzsch B, Pavlinkova G, Combined Atoh1 and Neurod1 Deletion Reveals Autonomous Growth of Auditory Nerve Fibers. Mol Neurobiol. 2020 Dec;57(12):5307-5323 |
1* | J:360528 Fritzsch B, Weng X, Yamoah EN, Qin T, Hui CC, Lebron-Mora L, Pavlinkova G, Sham MH, Irx3/5 Null Deletion in Mice Blocks Cochlea-Saccule Segregation and Disrupts the Auditory Tonotopic Map. J Comp Neurol. 2024 Dec;532(12):e70008 |
1 | J:180774 Grimsley-Myers CM, Sipe CW, Wu DK, Lu X, Redundant functions of Rac GTPases in inner ear morphogenesis. Dev Biol. 2012 Feb 15;362(2):172-86 |
1 | J:160258 Holley M, Rhodes C, Kneebone A, Herde MK, Fleming M, Steel KP, Emx2 and early hair cell development in the mouse inner ear. Dev Biol. 2010 Apr 15;340(2):547-56 |
1 | J:220948 Jahan I, Pan N, Kersigo J, Fritzsch B, Neurod1 suppresses hair cell differentiation in ear ganglia and regulates hair cell subtype development in the cochlea. PLoS One. 2010;5(7):e11661 |
1 | J:155405 Katayama K, Zine A, Ota M, Matsumoto Y, Inoue T, Fritzsch B, Aruga J, Disorganized innervation and neuronal loss in the inner ear of Slitrk6-deficient mice. PLoS One. 2009;4(11):e7786 |
1 | J:98458 Kiernan AE, Pelling AL, Leung KK, Tang AS, Bell DM, Tease C, Lovell-Badge R, Steel KP, Cheah KS, Sox2 is required for sensory organ development in the mammalian inner ear. Nature. 2005 Apr 21;434(7036):1031-5 |
1 | J:197212 Kim HJ, Woo HM, Ryu J, Bok J, Kim JW, Choi SB, Park MH, Park HY, Koo SK, Conditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development. PLoS One. 2013;8(2):e55609 |
1 | J:135991 Lefevre G, Michel V, Weil D, Lepelletier L, Bizard E, Wolfrum U, Hardelin JP, Petit C, A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth. Development. 2008 Apr;135(8):1427-37 |
1* | J:310860 Liu S, Wang Y, Lu Y, Li W, Liu W, Ma J, Sun F, Li M, Chen ZY, Su K, Li W, The Key Transcription Factor Expression in the Developing Vestibular and Auditory Sensory Organs: A Comprehensive Comparison of Spatial and Temporal Patterns. Neural Plast. 2018;2018:7513258 |
1 | J:160591 Liu Z, Owen T, Zhang L, Zuo J, Dynamic expression pattern of Sonic hedgehog in developing cochlear spiral ganglion neurons. Dev Dyn. 2010 Jun;239(6):1674-83 |
1 | J:239944 Lorenzen SM, Duggan A, Osipovich AB, Magnuson MA, Garcia-Anoveros J, Insm1 promotes neurogenic proliferation in delaminated otic progenitors. Mech Dev. 2015 Nov;138 Pt 3:233-45 |
1 | J:333396 Luo Z, Du Y, Li S, Zhang H, Shu M, Zhang D, He S, Wang G, Lu F, Liu Z, Three distinct Atoh1 enhancers cooperate for sound receptor hair cell development. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2119850119 |
1* | J:311540 Oliver BL, Young CA, Munnamalai V, Spatial and temporal expression of PORCN is highly dynamic in the developing mouse cochlea. Gene Expr Patterns. 2021 Sep 20;42:119214 |
1 | J:226669 Ono K, Kita T, Sato S, O'Neill P, Mak SS, Paschaki M, Ito M, Gotoh N, Kawakami K, Sasai Y, Ladher RK, FGFR1-Frs2/3 signalling maintains sensory progenitors during inner ear hair cell formation. PLoS Genet. 2014 Jan;10(1):e1004118 |
2 | J:335097 Qin T, Ho CC, Wang B, Hui CC, Sham MH, Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2206571119 |
1 | J:94587 Radde-Gallwitz K, Pan L, Gan L, Lin X, Segil N, Chen P, Expression of Islet1 marks the sensory and neuronal lineages in the mammalian inner ear. J Comp Neurol. 2004 Sep 27;477(4):412-21 |
1 | J:330615 Rim JH, Noh B, Koh YI, Joo SY, Oh KS, Kim K, Kim JA, Kim DH, Kim HY, Yoo JE, Lee ST, Bok JW, Lee MG, Jung J, Choi JY, Gee HY, Differential genetic diagnoses of adult post-lingual hearing loss according to the audiogram pattern and novel candidate gene evaluation. Hum Genet. 2022 Apr;141(3-4):915-927 |
2 | J:76464 Sahly I, El-Amraoui A, Abitbol M, Petit C, Dufier JL, Expression of myosin VIIA during mouse embryogenesis. Anat Embryol (Berl). 1997 Aug;196(2):159-70 |
1* | J:46373 Self T, Mahony M, Fleming J, Walsh J, Brown SD, Steel KP, Shaker-1 mutations reveal roles for myosin VIIA in both development and function of cochlear hair cells. Development. 1998 Feb;125(4):557-66 |
1* | J:164931 Sirmaci A, Erbek S, Price J, Huang M, Duman D, Cengiz FB, Bademci G, Tokgoz-Yilmaz S, Hismi B, Ozdag H, Ozturk B, Kulaksizoglu S, Yildirim E, Kokotas H, Grigoriadou M, Petersen MB, Shahin H, Kanaan M, King MC, Chen ZY, Blanton SH, Liu XZ, Zuchner S, AkarN, Tekin M, A truncating mutation in SERPINB6 is associated with autosomal-recessive nonsyndromic sensorineural hearing loss. Am J Hum Genet. 2010 May 14;86(5):797-804 |
1 | J:194385 Steffes G, Lorente-Canovas B, Pearson S, Brooker RH, Spiden S, Kiernan AE, Guenet JL, Steel KP, Mutanlallemand (mtl) and Belly Spot and Deafness (bsd) are two new mutations of Lmx1a causing severe cochlear and vestibular defects. PLoS One. 2012;7(11):e51065 |
1 | J:112461 Tang LS, Alger HM, Pereira FA, COUP-TFI controls Notch regulation of hair cell and support cell differentiation. Development. 2006 Sep;133(18):3683-93 |
1* | J:80025 Wallis D, Hamblen M, Zhou Y, Venken KJ, Schumacher A, Grimes HL, Zoghbi HY, Orkin SH, Bellen HJ, The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival. Development. 2003 Jan;130(1):221-32 |
1* | J:158680 Wansleeben C, Feitsma H, Montcouquiol M, Kroon C, Cuppen E, Meijlink F, Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b. Development. 2010 Apr;137(7):1067-73 |
1* | J:35133 Weil D, Levy G, Sahly I, Levi-Acobas F, Blanchard S, El-Amraoui A, Crozet F, Philippe H, Abitbol M, Petit C, Human myosin VIIA responsible for the Usher 1B syndrome: a predicted membrane-associated motor protein expressed in developing sensory epithelia. Proc Natl Acad Sci U S A. 1996 Apr 16;93(8):3232-7 |
1 | J:267715 Wiwatpanit T, Lorenzen SM, Cantu JA, Foo CZ, Hogan AK, Marquez F, Clancy JC, Schipma MJ, Cheatham MA, Duggan A, Garcia-Anoveros J, Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1. Nature. 2018 Nov;563(7733):691-695 |
1 | J:342339 Xia M, Wu M, Li Y, Liu Y, Jia G, Lou Y, Ma J, Gao Q, Xie M, Chen Y, He Y, Li H, Li W, Varying mechanical forces drive sensory epithelium formation. Sci Adv. 2023 Nov 3;9(44):eadf2664 |
1* | J:43752 Xiang M, Gao WQ, Hasson T, Shin JJ, Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells. Development. 1998 Oct;125(20):3935-46 |
1 | J:343328 Xie Z, Ma XH, Bai QF, Tang J, Sun JH, Jiang F, Guo W, Wang CM, Yang R, Wen YC, Wang FY, Chen YX, Zhang H, He DZ, Kelley MW, Yang S, Zhang WJ, ZBTB20 is essential for cochlear maturation and hearing in mice. Proc Natl Acad Sci U S A. 2023 Jun 13;120(24):e2220867120 |
Myo9a myosin IXa (Synonyms: 4732465J09Rik, C130068I12Rik) | |
Results | Reference |
1* | J:56684 Gorman SW, Haider NB, Grieshammer U, Swiderski RE, Kim E, Welch JW, Searby C, Leng S, Carmi R, Sheffield VC, Duhl DM, The cloning and developmental expression of unconventional myosin IXA (MYO9A) a gene in the Bardet-Biedl syndrome (BBS4) region at chromosome 15q22-q23. Genomics. 1999 Jul 15;59(2):150-60 |
Myo10 myosin X (Synonyms: D15Ertd600e, mKIAA0799, myosin-X) | |
Results | Reference |
2 | J:220582 Ju XD, Guo Y, Wang NN, Huang Y, Lai MM, Zhai YH, Guo YG, Zhang JH, Cao RJ, Yu HL, Cui L, Li YT, Wang XZ, Ding YQ, Zhu XJ, Both Myosin-10 isoforms are required for radial neuronal migration in the developing cerebral cortex. Cereb Cortex. 2014 May;24(5):1259-68 |
1 | J:268349 Kim HT, Yin W, Jin YJ, Panza P, Gunawan F, Grohmann B, Buettner C, Sokol AM, Preussner J, Guenther S, Kostin S, Ruppert C, Bhagwat AM, Ma X, Graumann J, Looso M, Guenther A, Adelstein RS, Offermanns S, Stainier DYR, Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease. Nat Commun. 2018 Nov 2;9(1):4600 |
Myo15a myosin XVA (Synonyms: Myo15) | |
Results | Reference |
1 | J:271898 Tadenev ALD, Akturk A, Devanney N, Mathur PD, Clark AM, Yang J, Tarchini B, GPSM2-GNAI Specifies the Tallest Stereocilia and Defines Hair Bundle Row Identity. Curr Biol. 2019 Feb 19; |
Myo16 myosin XVI (Synonyms: BM140241, C230040D10Rik, Nyap3) | |
Results | Reference |
1 | J:180006 Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T, NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54 |
Myo18b myosin XVIIIb (Synonyms: 4932408L24Rik, 4933411E19Rik) | |
Results | Reference |
1* | J:83690 Salamon M, Millino C, Raffaello A, Mongillo M, Sandri C, Bean C, Negrisolo E, Pallavicini A, Valle G, Zaccolo M, Schiaffino S, Lanfranchi G, Human MYO18B, a novel unconventional myosin heavy chain expressed in striated muscles moves into the myonuclei upon differentiation. J Mol Biol. 2003 Feb 7;326(1):137-49 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Myoc myocilin (Synonyms: GLC1A, TIGR) | |
Results | Reference |
1 | J:88222 Knaupp C, Flugel-Koch C, Goldwich A, Ohlmann A, Tamm ER, The expression of myocilin during murine eye development. Graefes Arch Clin Exp Ophthalmol. 2004 Apr;242(4):339-45 |
Myocd myocardin (Synonyms: Srfcp) | |
Results | Reference |
1 | J:166547 Airik R, Trowe MO, Foik A, Farin HF, Petry M, Schuster-Gossler K, Schweizer M, Scherer G, Kist R, Kispert A, Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme. Hum Mol Genet. 2010 Dec 15;19(24):4918-29 |
1 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1* | J:272619 Aydogdu N, Rudat C, Trowe MO, Kaiser M, Ludtke TH, Taketo MM, Christoffels VM, Moon A, Kispert A, TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827 |
1 | J:244068 Bohnenpoll T, Wittern AB, Mamo TM, Weiss AC, Rudat C, Kleppa MJ, Schuster-Gossler K, Wojahn I, Ludtke TH, Trowe MO, Kispert A, A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development. PLoS Genet. 2017 Aug;13(8):e1006951 |
1 | J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767 |
1* | J:82506 Du KL, Ip HS, Li J, Chen M, Dandre F, Yu W, Lu MM, Owens GK, Parmacek MS, Myocardin is a critical serum response factor cofactor in the transcriptional program regulating smooth muscle cell differentiation. Mol Cell Biol. 2003 Apr;23(7):2425-37 |
1 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:243772 Mamo TM, Wittern AB, Kleppa MJ, Bohnenpoll T, Weiss AC, Kispert A, BMP4 uses several different effector pathways to regulate proliferation and differentiation in the epithelial and mesenchymal tissue compartments of the developing mouse ureter. Hum Mol Genet. 2017 Sep 15;26(18):3553-3563 |
1 | J:202129 Martin E, Caubit X, Airik R, Vola C, Fatmi A, Kispert A, Fasano L, TSHZ3 and SOX9 regulate the timing of smooth muscle cell differentiation in the ureter by reducing myocardin activity. PLoS One. 2013;8(5):e63721 |
1 | J:311811 Trowe MO, Airik R, Weiss AC, Farin HF, Foik AB, Bettenhausen E, Schuster-Gossler K, Taketo MM, Kispert A, Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter. Development. 2012 Sep;139(17):3099-108 |
1 | J:214811 Weiss AC, Airik R, Bohnenpoll T, Greulich F, Foik A, Trowe MO, Rudat C, Costantini F, Adams RH, Kispert A, Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme. Development. 2014 Sep;141(17):3420-30 |
1* | J:279388 Weiss AC, Bohnenpoll T, Kurz J, Blank P, Airik R, Ludtke TH, Kleppa MJ, Deuper L, Kaiser M, Mamo TM, Costa R, von Hahn T, Trowe MO, Kispert A, Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme. J Pathol. 2019 Aug;248(4):452-463 |
1 | J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26 |
Myod1 myogenic differentiation 1 (Synonyms: bHLHc1, MYF3, MyoD, Myod-1) | |
Results | Reference |
2 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1 | J:74213 Bitoh Y, Shimotake T, Sasaki Y, Iwai N, Development of the pelvic floor muscles of murine embryos with anorectal malformations. J Pediatr Surg. 2002 Feb;37(2):224-7 |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1 | J:175458 Bren-Mattison Y, Hausburg M, Olwin BB, Growth of limb muscle is dependent on skeletal-derived Indian hedgehog. Dev Biol. 2011 Aug 15;356(2):486-95 |
1* | J:325107 Cao X, Yan Y, Luo X, Yang X, Cui H, Yang Y, Li H, Analyses of the circadian clock genes expression in whole embryos and maternal major tissues of mice. J Mol Histol. 2022 Apr;53(2):473-482 |
1 | J:196361 Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnani MG, Messina G, Cossu G, Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory. Dev Cell. 2013 Mar 25;24(6):586-99 |
1 | J:283675 Comai G, Heude E, Mella S, Paisant S, Pala F, Gallardo M, Langa F, Kardon G, Gopalakrishnan S, Tajbakhsh S, A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle. Elife. 2019 Sep 19;8:e47460 |
2 | J:332217 Feng J, Han X, Yuan Y, Cho CK, Janeckova E, Guo T, Pareek S, Rahman MS, Zheng B, Bi J, Jing J, Zhang M, Xu J, Ho TV, Chai Y, TGF-beta signaling and Creb5 cooperatively regulate Fgf18 to control pharyngeal muscle development. Elife. 2022 Dec 21;11 |
1 | J:186396 Gruenbaum-Cohen Y, Harel I, Umansky KB, Tzahor E, Snapper SB, Shilo BZ, Schejter ED, The actin regulator N-WASp is required for muscle-cell fusion in mice. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11211-6 |
1 | J:300927 Han X, Feng J, Guo T, Loh YE, Yuan Y, Ho TV, Cho CK, Li J, Jing J, Janeckova E, He J, Pei F, Bi J, Song B, Chai Y, Runx2-Twist1 interaction coordinates cranial neural crest guidance of soft palate myogenesis. Elife. 2021 Jan 22;10:e62387 |
1 | J:214255 Ipulan LA, Suzuki K, Sakamoto Y, Murashima A, Imai Y, Omori A, Nakagata N, Nishinakamura R, Valasek P, Yamada G, Nonmyocytic androgen receptor regulates the sexually dimorphic development of the embryonic bulbocavernosus muscle. Endocrinology. 2014 Jul;155(7):2467-79 |
2 | J:326543 Jiang A, Guo H, Jiang X, Tao J, Wu W, Liu H, G6PD Deficiency Is Crucial for Insulin Signaling Activation in Skeletal Muscle. Int J Mol Sci. 2022 Jul 4;23(13) |
1 | J:152867 Kanisicak O, Mendez JJ, Yamamoto S, Yamamoto M, Goldhamer DJ, Progenitors of skeletal muscle satellite cells express the muscle determination gene, MyoD. Dev Biol. 2009 Aug 1;332(1):131-41 |
1* | J:43635 Laurent A, Pinset C, Aurade F, Vidaud M, Montarras D, Expression of myotonic dystrophy protein kinase gene during in vivo and in vitro mouse myogenesis. Cell Mol Biol (Noisy-Le-Grand). 1997 Sep;43(6):881-8 |
1 | J:330270 Lv W, Jiang W, Luo H, Tong Q, Niu X, Liu X, Miao Y, Wang J, Guo Y, Li J, Zhan X, Hou Y, Peng Y, Wang J, Zhao S, Xu Z, Zuo B, Long noncoding RNA lncMREF promotes myogenic differentiation and muscle regeneration by interacting with the Smarca5/p300 complex. Nucleic Acids Res. 2022 Oct 14;50(18):10733-10755 |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
1 | J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97 |
2* | J:163363 Parreiras-E-Silva LT, Luchessi AD, Reis RI, Oliver C, Jamur MC, Ramos RG, Oliveira EB, Curi R, Costa-Neto CM, Evidences of a role for eukaryotic translation initiation factor 5A (eIF5A) in mouse embryogenesis and cell differentiation. J Cell Physiol. 2010 Nov;225(2):500-5 |
1 | J:129041 Potthoff MJ, Arnold MA, McAnally J, Richardson JA, Bassel-Duby R, Olson EN, Regulation of skeletal muscle sarcomere integrity and postnatal muscle function by Mef2c. Mol Cell Biol. 2007 Dec;27(23):8143-51 |
1 | J:202131 Sakai H, Sato T, Sakurai H, Yamamoto T, Hanaoka K, Montarras D, Sehara-Fujisawa A, Fetal skeletal muscle progenitors have regenerative capacity after intramuscular engraftment in dystrophin deficient mice. PLoS One. 2013;8(5):e63016 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1* | J:22984 Venuti JM, Morris JH, Vivian JL, Olson EN, Klein WH, Myogenin is required for late but not early aspects of myogenesis during mouse development. J Cell Biol. 1995 Feb;128(4):563-76 |
1 | J:168032 Zacharias AL, Lewandoski M, Rudnicki MA, Gage PJ, Pitx2 is an upstream activator of extraocular myogenesis and survival. Dev Biol. 2011 Jan 15;349(2):395-405 |
2* | J:64537 Zhao W, Dhoot GK, Skeletal muscle precursors in mouse esophagus are determined during early fetal development. Dev Dyn. 2000 Sep;219(1):10-20 |
1 | J:243660 Zhu XJ, Yuan X, Wang M, Fang Y, Liu Y, Zhang X, Yang X, Li Y, Li J, Li F, Dai ZM, Qiu M, Zhang Z, Zhang Z, A Wnt/Notch/Pax7 signaling network supports tissue integrity in tongue development. J Biol Chem. 2017 Jun 02;292(22):9409-9419 |
Myog myogenin (Synonyms: bHLHc3, myo) | |
Results | Reference |
1 | J:207514 Acharjee S, Chung TK, Gopinadhan S, Shankar SR, Wang Y, Li L, Vercherat C, Gulbagci NT, Rossner M, Taneja R, Sharp-1 regulates TGF-beta signaling and skeletal muscle regeneration. J Cell Sci. 2014 Feb 1;127(Pt 3):599-608 |
1 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1 | J:74213 Bitoh Y, Shimotake T, Sasaki Y, Iwai N, Development of the pelvic floor muscles of murine embryos with anorectal malformations. J Pediatr Surg. 2002 Feb;37(2):224-7 |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1 | J:175458 Bren-Mattison Y, Hausburg M, Olwin BB, Growth of limb muscle is dependent on skeletal-derived Indian hedgehog. Dev Biol. 2011 Aug 15;356(2):486-95 |
1* | J:325107 Cao X, Yan Y, Luo X, Yang X, Cui H, Yang Y, Li H, Analyses of the circadian clock genes expression in whole embryos and maternal major tissues of mice. J Mol Histol. 2022 Apr;53(2):473-482 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:283675 Comai G, Heude E, Mella S, Paisant S, Pala F, Gallardo M, Langa F, Kardon G, Gopalakrishnan S, Tajbakhsh S, A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle. Elife. 2019 Sep 19;8:e47460 |
1* | J:238480 He K, Hu J, Yu H, Wang L, Tang F, Gu J, Ge L, Wang H, Li S, Hu P, Jin Y, Serine/Threonine Kinase 40 (Stk40) Functions as a Novel Regulator of Skeletal Muscle Differentiation. J Biol Chem. 2017 Jan 06;292(1):351-360 |
1 | J:103319 Horst D, Ustanina S, Sergi C, Mikuz G, Juergens H, Braun T, Vorobyov E, Comparative expression analysis of Pax3 and Pax7 during mouse myogenesis. Int J Dev Biol. 2006;50(1):47-54 |
1 | J:214255 Ipulan LA, Suzuki K, Sakamoto Y, Murashima A, Imai Y, Omori A, Nakagata N, Nishinakamura R, Valasek P, Yamada G, Nonmyocytic androgen receptor regulates the sexually dimorphic development of the embryonic bulbocavernosus muscle. Endocrinology. 2014 Jul;155(7):2467-79 |
2 | J:326543 Jiang A, Guo H, Jiang X, Tao J, Wu W, Liu H, G6PD Deficiency Is Crucial for Insulin Signaling Activation in Skeletal Muscle. Int J Mol Sci. 2022 Jul 4;23(13) |
1 | J:60987 Kablar B, Tajbakhsh S, Rudnicki MA, Transdifferentiation of esophageal smooth to skeletal muscle is myogenic bHLH factor-dependent. Development. 2000 Apr;127(8):1627-39 |
1* | J:43635 Laurent A, Pinset C, Aurade F, Vidaud M, Montarras D, Expression of myotonic dystrophy protein kinase gene during in vivo and in vitro mouse myogenesis. Cell Mol Biol (Noisy-Le-Grand). 1997 Sep;43(6):881-8 |
1* | J:52277 Lu J, Webb R, Richardson JA, Olson EN, MyoR: a muscle-restricted basic helix-loop-helix transcription factor that antagonizes the actions of MyoD. Proc Natl Acad Sci U S A. 1999 Jan 19;96(2):552-7 |
1 | J:160383 Messina G, Biressi S, Monteverde S, Magli A, Cassano M, Perani L, Roncaglia E, Tagliafico E, Starnes L, Campbell CE, Grossi M, Goldhamer DJ, Gronostajski RM, Cossu G, Nfix regulates fetal-specific transcription in developing skeletal muscle. Cell. 2010 Feb 19;140(4):554-66 |
1 | J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97 |
1 | J:242767 Nunes AM, Wuebbles RD, Sarathy A, Fontelonga TM, Deries M, Burkin DJ, Thorsteinsdottir S, Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy. Hum Mol Genet. 2017 Jun 01;26(11):2018-2033 |
1 | J:129041 Potthoff MJ, Arnold MA, McAnally J, Richardson JA, Bassel-Duby R, Olson EN, Regulation of skeletal muscle sarcomere integrity and postnatal muscle function by Mef2c. Mol Cell Biol. 2007 Dec;27(23):8143-51 |
1 | J:180846 Saito K, Ogawa A, Toyofuku K, Hosoi Y, Soma M, Iha M, Kasuga K, Kojima I, Kobayashi M, Relationships between homeoprotein EGAM1C and the expression of the placental prolactin gene family in mouse placentae and trophoblast stem cells. Reproduction. 2011 Feb;141(2):259-68 |
1 | J:198574 Sugimoto Y, Takimoto A, Akiyama H, Kist R, Scherer G, Nakamura T, Hiraki Y, Shukunami C, Scx+/Sox9+ progenitors contribute to the establishment of the junction between cartilage and tendon/ligament. Development. 2013 Jun;140(11):2280-8 |
1 | J:67329 Sumiyoshi H, Laub F, Yoshioka H, Ramirez F, Embryonic expression of type XIX collagen is transient and confined to muscle cells. Dev Dyn. 2001 Feb;220(2):155-62 |
1 | J:172698 von Maltzahn J, Wulf V, Matern G, Willecke K, Connexin39 deficient mice display accelerated myogenesis and regeneration of skeletal muscle. Exp Cell Res. 2011 May 1;317(8):1169-78 |
1 | J:168032 Zacharias AL, Lewandoski M, Rudnicki MA, Gage PJ, Pitx2 is an upstream activator of extraocular myogenesis and survival. Dev Biol. 2011 Jan 15;349(2):395-405 |
1 | J:223040 Zhang T, Gunther S, Looso M, Kunne C, Kruger M, Kim J, Zhou Y, Braun T, Prmt5 is a regulator of muscle stem cell expansion in adult mice. Nat Commun. 2015;6:7140 |
2* | J:64537 Zhao W, Dhoot GK, Skeletal muscle precursors in mouse esophagus are determined during early fetal development. Dev Dyn. 2000 Sep;219(1):10-20 |
1 | J:243660 Zhu XJ, Yuan X, Wang M, Fang Y, Liu Y, Zhang X, Yang X, Li Y, Li J, Li F, Dai ZM, Qiu M, Zhang Z, Zhang Z, A Wnt/Notch/Pax7 signaling network supports tissue integrity in tongue development. J Biol Chem. 2017 Jun 02;292(22):9409-9419 |
Myom1 myomesin 1 (Synonyms: D430047A17Rik, skelemin) | |
Results | Reference |
1* | J:166500 Schoenauer R, Lange S, Hirschy A, Ehler E, Perriard JC, Agarkova I, Myomesin 3, a novel structural component of the M-band in striated muscle. J Mol Biol. 2008 Feb 15;376(2):338-51 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
1 | J:311867 Zhang X, Wang Z, Xu Q, Chen Y, Liu W, Zhong T, Li H, Quan C, Zhang L, Cui CP, Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium. iScience. 2021 Oct 22;24(10):103097 |
Myom2 myomesin 2 | |
Results | Reference |
1* | J:166500 Schoenauer R, Lange S, Hirschy A, Ehler E, Perriard JC, Agarkova I, Myomesin 3, a novel structural component of the M-band in striated muscle. J Mol Biol. 2008 Feb 15;376(2):338-51 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Myom3 myomesin family, member 3 (Synonyms: 8430427K15Rik) | |
Results | Reference |
2* | J:166500 Schoenauer R, Lange S, Hirschy A, Ehler E, Perriard JC, Agarkova I, Myomesin 3, a novel structural component of the M-band in striated muscle. J Mol Biol. 2008 Feb 15;376(2):338-51 |
Myrf myelin regulatory factor (Synonyms: Gm98, LOC225908, LOC386531) | |
Results | Reference |
1* | J:337458 Waldhauser V, Baroti T, Frob F, Wegner M, PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12) |
1* | J:288669 Wedel M, Frob F, Elsesser O, Wittmann MT, Lie DC, Reis A, Wegner M, Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation. Nucleic Acids Res. 2020 May 21;48(9):4839-4857 |
Myt1 myelin transcription factor 1 (Synonyms: mKIAA0835, Nzf2, NZF-2a, NZF-2b, Nztf2) | |
Results | Reference |
1 | J:272578 Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G, Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. Dev Cell. 2019 Jan 7;48(1):49-63.e7 |
1* | J:359190 Nagai M, Porter RS, Miyasato M, Wang A, Gavilan CM, Hughes ED, Wu MC, Saunders TL, Iwase S, Neuronal splicing of the unmethylated histone H3K4 reader, PHF21A, prevents excessive synaptogenesis. J Biol Chem. 2024 Nov;300(11):107881 |
1 | J:136131 Wang S, Hecksher-Sorensen J, Xu Y, Zhao A, Dor Y, Rosenberg L, Serup P, Gu G, Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation. Dev Biol. 2008 May 15;317(2):531-40 |
Myt1l myelin transcription factor 1-like (Synonyms: 2900046C06Rik, 2900093J19Rik, C630034G21Rik, mKIAA1106, Nztf1, Pmng1, Png-1) | |
Results | Reference |
1* | J:114661 Lyu YL, Lin CP, Azarova AM, Cai L, Wang JC, Liu LF, Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Mol Cell Biol. 2006 Nov;26(21):7929-41 |
1* | J:359190 Nagai M, Porter RS, Miyasato M, Wang A, Gavilan CM, Hughes ED, Wu MC, Saunders TL, Iwase S, Neuronal splicing of the unmethylated histone H3K4 reader, PHF21A, prevents excessive synaptogenesis. J Biol Chem. 2024 Nov;300(11):107881 |
Naa15 N(alpha)-acetyltransferase 15, NatA auxiliary subunit (Synonyms: 5730450D16Rik, ASTBDN, mNAT1, Narg1, Tbdn-1, tubedown) | |
Results | Reference |
1 | J:78769 Paradis H, Liu CY, Saika S, Azhar M, Doetschman T, Good WV, Nayak R, Laver N, Kao CW, Kao WW, Gendron RL, Tubedown-1 in remodeling of the developing vitreal vasculature in vivo and regulation of capillary outgrowth in vitro. Dev Biol. 2002 Sep 1;249(1):140-55 |
Nab2 Ngfi-A binding protein 2 | |
Results | Reference |
2 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
Naca nascent polypeptide-associated complex alpha polypeptide (Synonyms: LOC380777, mKIAA0363, skNAC) | |
Results | Reference |
1* | J:259125 Yang J, Hung LH, Licht T, Kostin S, Looso M, Khrameeva E, Bindereif A, Schneider A, Braun T, RBM24 is a major regulator of muscle-specific alternative splicing. Dev Cell. 2014 Oct 13;31(1):87-99 |
Naga N-acetyl galactosaminidase, alpha | |
Results | Reference |
1 | J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90 |
Naip1 NLR family, apoptosis inhibitory protein 1 (Synonyms: Birc1a, D13Lsd1, Naip) | |
Results | Reference |
1* | J:79943 Ingram-Crooks J, Holcik M, Drmanic S, MacKenzie AE, Distinct expression of neuronal apoptosis inhibitory protein (NAIP) during murine development. Neuroreport. 2002 Mar 25;13(4):397-402 |
Nanog Nanog homeobox (Synonyms: 2410002E02Rik, ecat4, ENK) | |
Results | Reference |
1 | J:167041 Cook MS, Munger SC, Nadeau JH, Capel B, Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background. Development. 2011 Jan;138(1):23-32 |
1* | J:90050 Hart AH, Hartley L, Ibrahim M, Robb L, Identification, cloning and expression analysis of the pluripotency promoting Nanog genes in mouse and human. Dev Dyn. 2004 May;230(1):187-98 |
1* | J:172286 Miranda A, Pericuesta E, Ramirez MA, Gutierrez-Adan A, Prion protein expression regulates embryonic stem cell pluripotency and differentiation. PLoS One. 2011;6(4):e18422 |
1* | J:98712 Yamaguchi S, Kimura H, Tada M, Nakatsuji N, Tada T, Nanog expression in mouse germ cell development. Gene Expr Patterns. 2005 Jun;5(5):639-646 |
Nanos2 nanos C2HC-type zinc finger 2 (Synonyms: nos2) | |
Results | Reference |
1* | J:158581 Barrios F, Filipponi D, Pellegrini M, Paronetto MP, Di Siena S, Geremia R, Rossi P, De Felici M, Jannini EA, Dolci S, Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells. J Cell Sci. 2010 Mar 15;123(Pt 6):871-80 |
1* | J:165736 Guerquin MJ, Duquenne C, Lahaye JB, Tourpin S, Habert R, Livera G, New testicular mechanisms involved in the prevention of fetal meiotic initiation in mice. Dev Biol. 2010 Oct 15;346(2):320-30 |
1* | J:241573 Pui HP, Saga Y, Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling. Mech Dev. 2017 Apr;144(Pt B):125-139 |
1 | J:157579 Suzuki A, Igarashi K, Aisaki K, Kanno J, Saga Y, NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs. Proc Natl Acad Sci U S A. 2010 Feb 23;107(8):3594-9 |
1* | J:117055 Suzuki A, Tsuda M, Saga Y, Functional redundancy among Nanos proteins and a distinct role of Nanos2 during male germ cell development. Development. 2007 Jan;134(1):77-83 |
1* | J:119032 Tsuda M, Kiso M, Saga Y, Implication of nanos2-3'UTR in the expression and function of nanos2. Mech Dev. 2006 Jun;123(6):440-9 |
Nanos3 nanos C2HC-type zinc finger 3 (Synonyms: nos3) | |
Results | Reference |
1* | J:165736 Guerquin MJ, Duquenne C, Lahaye JB, Tourpin S, Habert R, Livera G, New testicular mechanisms involved in the prevention of fetal meiotic initiation in mice. Dev Biol. 2010 Oct 15;346(2):320-30 |
1* | J:117055 Suzuki A, Tsuda M, Saga Y, Functional redundancy among Nanos proteins and a distinct role of Nanos2 during male germ cell development. Development. 2007 Jan;134(1):77-83 |
1 | J:162904 Yamaji M, Tanaka T, Shigeta M, Chuma S, Saga Y, Saitou M, Functional reconstruction of NANOS3 expression in the germ cell lineage by a novel transgenic reporter reveals distinct subcellular localizations of NANOS3. Reproduction. 2010 Feb;139(2):381-93 |
Nap1l1 nucleosome assembly protein 1-like 1 (Synonyms: D10Ertd68e) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Nap1l5 nucleosome assembly protein 1-like 5 (Synonyms: 1110020M21Rik) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Napa N-ethylmaleimide sensitive fusion protein attachment protein alpha (Synonyms: 1500039N14Rik, a-SNAP, hyh, RA81, SNAPA, SNARE) | |
Results | Reference |
1 | J:143546 Ferland RJ, Batiz LF, Neal J, Lian G, Bundock E, Lu J, Hsiao YC, Diamond R, Mei D, Banham AH, Brown PJ, Vanderburg CR, Joseph J, Hecht JL, Folkerth R, Guerrini R, Walsh CA, Rodriguez EM, Sheen VL, Disruption of neural progenitors along the ventricular and subventricular zones in periventricular heterotopia. Hum Mol Genet. 2009 Feb 1;18(3):497-516 |
Napsa napsin A aspartic peptidase (Synonyms: Kdap, NAP1, napsin, pronapsin) | |
Results | Reference |
1 | J:74167 Mori K, Kon Y, Konno A, Iwanaga T, Cellular distribution of napsin (kidney-derived aspartic protease-like protein, KAP) mRNA in the kidney, lung and lymphatic organs of adult and developing mice. Arch Histol Cytol. 2001 Aug;64(3):319-27 |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
Nasp nuclear autoantigenic sperm protein (histone-binding) (Synonyms: 5033430J04Rik, D4Ertd767e, Epcs32, Nasp-T) | |
Results | Reference |
1 | J:179807 Grellscheid S, Dalgliesh C, Storbeck M, Best A, Liu Y, Jakubik M, Mende Y, Ehrmann I, Curk T, Rossbach K, Bourgeois CF, Stevenin J, Grellscheid D, Jackson MS, Wirth B, Elliott DJ, Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2beta in development. PLoS Genet. 2011 Dec;7(12):e1002390 |
1 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
Nav2 neuron navigator 2 (Synonyms: 5330421F07Rik, HELAD1, mKIAA3015, POMFIL2, Rainb1, RAINB2, Unc53H2) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Nav3 neuron navigator 3 (Synonyms: 4732483H20Rik, 9630020C08Rik, mKIAA0938, POMFIL1, Pomfil1p, steerin 3, unc53H3) | |
Results | Reference |
1 | J:77366 Coy JF, Wiemann S, Bechmann I, Bachner D, Nitsch R, Kretz O, Christiansen H, Poustka A, Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms. Gene. 2002 May 15;290(1-2):73-94 |
Nbas neuroblastoma amplified sequence (Synonyms: 4933425L03Rik) | |
Results | Reference |
1* | J:265842 Palagano E, Zuccarini G, Prontera P, Borgatti R, Stangoni G, Elisei S, Mantero S, Menale C, Forlino A, Uva P, Oppo M, Vezzoni P, Villa A, Merlo GR, Sobacchi C, Mutations in the Neuroblastoma Amplified Sequence gene in a family affected by Acrofrontofacionasal Dysostosis type 1. Bone. 2018 Sep;114:125-136 |
1* | J:316637 Strogantsev R, Krueger F, Yamazawa K, Shi H, Gould P, Goldman-Roberts M, McEwen K, Sun B, Pedersen R, Ferguson-Smith AC, Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression. Genome Biol. 2015 May 30;16:112 |
Nbea neurobeachin (Synonyms: mKIAA1544) | |
Results | Reference |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
Nbl1 NBL1, DAN family BMP antagonist (Synonyms: D4H1S1733E, DAN, Dana, NO3) | |
Results | Reference |
1 | J:73145 Lu MM, Yang H, Zhang L, Shu W, Blair DG, Morrisey EE, The bone morphogenic protein antagonist gremlin regulates proximal-distal patterning of the lung. Dev Dyn. 2001 Dec;222(4):667-80 |
Ncam1 neural cell adhesion molecule 1 (Synonyms: CD56, E-NCAM, NCAM, NCAM-1, NCAM-120, NCAM-140, NCAM-180) | |
Results | Reference |
1 | J:241827 Aoki M, Takeuchi H, Nakashima A, Nishizumi H, Sakano H, Possible roles of Robo1+ ensheathing cells in guiding dorsal-zone olfactory sensory neurons in mouse. Dev Neurobiol. 2013 Nov;73(11):828-40 |
1* | J:229480 Baker JL, Wood B, Karpinski BA, LaMantia AS, Maynard TM, Testicular receptor 2, Nr2c1, is associated with stem cells in the developing olfactory epithelium and other cranial sensory and skeletal structures. Gene Expr Patterns. 2016 Jan;20(1):71-9 |
1* | J:199435 Barraud P, St John JA, Stolt CC, Wegner M, Baker CV, Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Biol Open. 2013 Jul 15;2(7):750-9 |
1* | J:208419 Basta JM, Robbins L, Kiefer SM, Dorsett D, Rauchman M, Sall1 balances self-renewal and differentiation of renal progenitor cells. Development. 2014 Mar;141(5):1047-58 |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
1 | J:95084 Buckiova D, Syka J, Development of the inner ear in Splotch mutant mice. Neuroreport. 2004 Sep 15;15(13):2001-5 |
1* | J:71338 Chung WW, Lagenaur CF, Yan YM, Lund JS, Developmental expression of neural cell adhesion molecules in the mouse neocortex and olfactory bulb. J Comp Neurol. 1991 Dec 8;314(2):290-305 |
1 | J:74090 Clarris HJ, Key B, Expression of glycoproteins in the vomeronasal organ reveals a novel spatiotemporal pattern of sensory neurone maturation. J Neurobiol. 2001 Feb 5;46(2):113-25 |
2 | J:308786 Delgado C, Bu L, Zhang J, Liu FY, Sall J, Liang FX, Furley AJ, Fishman GI, Neural cell adhesion molecule is required for ventricular conduction system development. Development. 2021 Jun 1;148(11):dev199431 |
1* | J:47986 Dellovade TL, Pfaff DW, Schwanzel-Fukuda M, The gonadotropin-releasing hormone system does not develop in Small-Eye (Sey) mouse phenotype. Brain Res Dev Brain Res. 1998 May 15;107(2):233-40 |
1 | J:173576 Di Giovanni V, Alday A, Chi L, Mishina Y, Rosenblum ND, Alk3 controls nephron number and androgen production via lineage-specific effects in intermediate mesoderm. Development. 2011 Jul;138(13):2717-27 |
1 | J:54722 Engelkamp D, Rashbass P, Seawright A, van Heyningen V, Role of Pax6 in development of the cerebellar system. Development. 1999 Aug;126(16):3585-96 |
1 | J:96462 Fujita E, Urase K, Soyama A, Kouroku Y, Momoi T, Distribution of RA175/TSLC1/SynCAM, a member of the immunoglobulin superfamily, in the developing nervous system. Brain Res Dev Brain Res. 2005 Feb 8;154(2):199-209 |
1 | J:96397 Halfter W, Willem M, Mayer U, Basement membrane-dependent survival of retinal ganglion cells. Invest Ophthalmol Vis Sci. 2005 Mar;46(3):1000-9 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:147995 Kawauchi S, Kim J, Santos R, Wu HH, Lander AD, Calof AL, Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11. Development. 2009 May;136(9):1453-64 |
1 | J:195630 Krolewski RC, Packard A, Jang W, Wildner H, Schwob JE, Ascl1 (Mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium. PLoS One. 2012;7(12):e51737 |
1 | J:83383 Levi G, Puche AC, Mantero S, Barbieri O, Trombino S, Paleari L, Egeo A, Merlo GR, The Dlx5 homeodomain gene is essential for olfactory development and connectivity in the mouse. Mol Cell Neurosci. 2003 Apr;22(4):530-43 |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1 | J:137605 Manuel M, Pratt T, Liu M, Jeffery G, Price DJ, Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance. BMC Dev Biol. 2008;8:59 |
1 | J:164033 Miller AM, Maurer LR, Zou DJ, Firestein S, Greer CA, Axon fasciculation in the developing olfactory nerve. Neural Dev. 2010;5(1):20 |
1 | J:261989 Nakajima Y, Kiyonari H, Mukumoto Y, Yokoyama T, The Inv compartment of renal cilia is an intraciliary signal-activating center to phosphorylate ANKS6. Kidney Int. 2018 May;93(5):1108-1117 |
1* | J:20745 Naruse I, Fukui Y, Keino H, Taniguchi M, The arrest of luteinizing hormone-releasing hormone neuronal migration in the genetic arhinencephalic mouse embryo (Pdn/Pdn). Brain Res Dev Brain Res. 1994 Sep 16;81(2):178-84 |
2 | J:81334 Obara N, Suzuki Y, Nagai Y, Nishiyama H, Mizoguchi I, Takeda M, Expression of neural cell-adhesion molecule mRNA during mouse molar tooth development. Arch Oral Biol. 2002 Nov;47(11):805-13 |
1 | J:15524 Obara N, Takeda M, Expression of the neural cell adhesion molecule (NCAM) during second- and third-molar development in the mouse. Anat Embryol (Berl). 1993 Jul;188(1):13-20 |
1 | J:154276 Ohsawa S, Hamada S, Yoshida H, Miura M, Caspase-mediated changes in histone H1 in early apoptosis: prolonged caspase activation in developing olfactory sensory neurons. Cell Death Differ. 2008 Sep;15(9):1429-39 |
1 | J:133714 Paez P, Batiz LF, Roales-Bujan R, Rodriguez-Perez LM, Rodriguez S, Jimenez AJ, Rodriguez EM, Perez-Figares JM, Patterned neuropathologic events occurring in hyh congenital hydrocephalic mutant mice. J Neuropathol Exp Neurol. 2007 Dec;66(12):1082-92 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1 | J:313294 Raucci F, Tiong JD, Wray S, P75 nerve growth factor receptors modulate development of GnRH neurons and olfactory ensheating cells. Front Neurosci. 2013;7:262 |
1 | J:195266 Reginensi A, Scott RP, Gregorieff A, Bagherie-Lachidan M, Chung C, Lim DS, Pawson T, Wrana J, McNeill H, Yap- and Cdc42-Dependent Nephrogenesis and Morphogenesis during Mouse Kidney Development. PLoS Genet. 2013 Mar;9(3):e1003380 |
1 | J:346405 Vitureira N, Andres R, Perez-Martinez E, Martinez A, Bribian A, Blasi J, Chelliah S, Lopez-Domenech G, De Castro F, Burgaya F, McNagny K, Soriano E, Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation. PLoS One. 2010 Aug 10;5(8):e12003 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
1 | J:234179 Xiao Y, Thoresen DT, Miao L, Williams JS, Wang C, Atit RP, Wong SY, Brownell I, A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development. PLoS Genet. 2016 Jul;12(7):e1006150 |
1 | J:363737 Xue Z, Xuan H, Lau K, Su Y, Wegener M, Li K, Turner L, Adams M, Shi X, Wen H, Expression of ENL YEATS domain tumor mutations in nephrogenic or stromal lineage impairs kidney development. Nat Commun. 2025 Mar 14;16(1):2531 |
Ncam2 neural cell adhesion molecule 2 (Synonyms: Ncam-2, Ocam, R4B12 antigen, RNCAM) | |
Results | Reference |
1* | J:208419 Basta JM, Robbins L, Kiefer SM, Dorsett D, Rauchman M, Sall1 balances self-renewal and differentiation of renal progenitor cells. Development. 2014 Mar;141(5):1047-58 |
2* | J:229257 Gu Z, Imai F, Kim IJ, Fujita H, Katayama Ki, Mori K, Yoshihara Y, Yoshida Y, Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550 |
1 | J:162564 Ohsawa S, Hamada S, Kuida K, Yoshida H, Igaki T, Miura M, Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13366-71 |
Ncan neurocan (Synonyms: Cspg3, Cspg3-rs, Tgfbit) | |
Results | Reference |
1* | J:171511 Cichon S, Muhleisen TW, Degenhardt FA, Mattheisen M, Miro X, Strohmaier J, Steffens M, Meesters C, Herms S, Weingarten M, Priebe L, Haenisch B, Alexander M, Vollmer J, Breuer R, Schmal C, Tessmann P, Moebus S, Wichmann HE, Schreiber S, Muller-Myhsok B, Lucae S, Jamain S, Leboyer M, Bellivier F, Etain B, Henry C, Kahn JP, Heath S, Hamshere M, O'Donovan MC, Owen MJ, Craddock N, Schwarz M, Vedder H, Kammerer-Ciernioch J, Reif A, Sasse J, Bauer M, Hautzinger M, Wright A, Mitchell PB, Schofield PR, Montgomery, Genome-wide association study identifies genetic variation in neurocan as a susceptibility factor for bipolar disorder. Am J Hum Genet. 2011 Mar 11;88(3):372-81 |
1* | J:104312 Li HP, Oohira A, Ogawa M, Kawamura K, Kawano H, Aberrant trajectory of thalamocortical axons associated with abnormal localization of neurocan immunoreactivity in the cerebral neocortex of reeler mutant mice. Eur J Neurosci. 2005 Dec;22(11):2689-96 |
4 | J:346596 Mubuchi A, Takechi M, Nishio S, Matsuda T, Itoh Y, Sato C, Kitajima K, Kitagawa H, Miyata S, Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons. Elife. 2024 Mar 21;12 |
1 | J:50400 Rice DS, Sheldon M, D'Arcangelo G, Nakajima K, Goldowitz D, Curran T, Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain. Development. 1998 Sep;125(18):3719-29 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
3 | J:70858 Zhou XH, Brakebusch C, Matthies H, Oohashi T, Hirsch E, Moser M, Krug M, Seidenbecher CI, Boeckers TM, Rauch U, Buettner R, Gundelfinger ED, Fassler R, Neurocan is dispensable for brain development. Mol Cell Biol. 2001 Sep;21(17):5970-8 |
Ncapd2 non-SMC condensin I complex, subunit D2 (Synonyms: 2810406C15Rik, 2810465G24Rik, CAP-D2, CNAP1, mKIAA0159) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
Ncapg non-SMC condensin I complex, subunit G (Synonyms: 5730507H05Rik, Hcapg, MFT.M05.13) | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Nck1 non-catalytic region of tyrosine kinase adaptor protein 1 (Synonyms: 6330586M15Rik, D230010O13Rik, Nck) | |
Results | Reference |
1 | J:196018 Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W, Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell Rep. 2012 Jul 26;2(1):52-61 |
Nckap1 NCK-associated protein 1 (Synonyms: H19, Hem-2, Hem2, mh19, Nap1) | |
Results | Reference |
1 | J:207861 Manthey AL, Lachke SA, FitzGerald PG, Mason RW, Scheiblin DA, McDonald JH, Duncan MK, Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development. Mech Dev. 2014 Feb;131:86-110 |
1 | J:180006 Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T, NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54 |
Nckap5l NCK-associated protein 5-like (Synonyms: C230021P08Rik) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Ncl nucleolin (Synonyms: B530004O11Rik, C23) | |
Results | Reference |
2* | J:124786 Xie M, Kobayashi I, Kiyoshima T, Yamaza H, Honda JY, Takahashi K, Enoki N, Akamine A, Sakai H, Functional implication of nucleolin in the mouse first molar development. J Biol Chem. 2007 Aug 10;282(32):23275-83 |
Ncoa1 nuclear receptor coactivator 1 (Synonyms: bHLHe74, KAT13A, SRC-1, SRC1, SRC-a/NCoA-1, steroid receptor coactivator-1) | |
Results | Reference |
1 | J:182838 Chen X, Liu Z, Xu J, The cooperative function of nuclear receptor coactivator 1 (NCOA1) and NCOA3 in placental development and embryo survival. Mol Endocrinol. 2010 Oct;24(10):1917-34 |
1 | J:309486 Chen X, Qin L, Liu Z, Liao L, Martin JF, Xu J, Knockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy Phenotype. Int J Biol Sci. 2015;11(9):1056-72 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1* | J:189008 Jia Y, Viswakarma N, Crawford SE, Sarkar J, Sambasiva Rao M, Karpus WJ, Kanwar YS, Zhu YJ, Reddy JK, Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. Mech Dev. 2012 Sep;129(9-12):193-207 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Ncoa2 nuclear receptor coactivator 2 (Synonyms: bHLHe75, D1Ertd433e, glucocorticoid receptor-interacting protein 1, Grip1, KAT13C, SRC-2, TIF-2, TIF2, TIF2/GRIP-1) | |
Results | Reference |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
Ncoa3 nuclear receptor coactivator 3 (Synonyms: 2010305B15Rik, AIB1, bHLHe42, KAT13B, pCIP, RAC3, Src3, TRAM-1, TRAM1) | |
Results | Reference |
1 | J:182838 Chen X, Liu Z, Xu J, The cooperative function of nuclear receptor coactivator 1 (NCOA1) and NCOA3 in placental development and embryo survival. Mol Endocrinol. 2010 Oct;24(10):1917-34 |
1 | J:309486 Chen X, Qin L, Liu Z, Liao L, Martin JF, Xu J, Knockout of SRC-1 and SRC-3 in Mice Decreases Cardiomyocyte Proliferation and Causes a Noncompaction Cardiomyopathy Phenotype. Int J Biol Sci. 2015;11(9):1056-72 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
Ncoa4 nuclear receptor coactivator 4 (Synonyms: 1110034E15Rik, 4432406M01Rik) | |
Results | Reference |
3* | J:170046 Kollara A, Brown TJ, Variable expression of nuclear receptor coactivator 4 (NcoA4) during mouse embryonic development. J Histochem Cytochem. 2010 Jul;58(7):595-609 |
Ncoa6 nuclear receptor coactivator 6 (Synonyms: AIB3, ASC-2, ASC2, mKIAA0181, NRC, PRIP, RAP250) | |
Results | Reference |
1* | J:189008 Jia Y, Viswakarma N, Crawford SE, Sarkar J, Sambasiva Rao M, Karpus WJ, Kanwar YS, Zhu YJ, Reddy JK, Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. Mech Dev. 2012 Sep;129(9-12):193-207 |
Ncor1 nuclear receptor co-repressor 1 (Synonyms: 5730405M06Rik, A230020K14Rik, mKIAA1047, N-CoR, Rxrip13) | |
Results | Reference |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
Ncor2 nuclear receptor co-repressor 2 (Synonyms: SMRT, SMRTe) | |
Results | Reference |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
Nde1 nudE neurodevelopment protein 1 (Synonyms: 2810027M15Rik, mNudE) | |
Results | Reference |
1* | J:84075 Toyo-oka K, Shionoya A, Gambello MJ, Cardoso C, Leventer R, Ward HL, Ayala R, Tsai LH, Dobyns W, Ledbetter D, Hirotsune S, Wynshaw-Boris A, 14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nat Genet. 2003 Jul;34(3):274-85 |
Ndel1 nudE neurodevelopment protein 1 like 1 (Synonyms: 2600006O07Rik, mNudel) | |
Results | Reference |
1 | J:216299 Toyo-oka K, Wachi T, Hunt RF, Baraban SC, Taya S, Ramshaw H, Kaibuchi K, Schwarz QP, Lopez AF, Wynshaw-Boris A, 14-3-3epsilon and zeta regulate neurogenesis and differentiation of neuronal progenitor cells in the developing brain. J Neurosci. 2014 Sep 3;34(36):12168-81 |
Ndn necdin, MAGE family member (Synonyms: Peg6) | |
Results | Reference |
2 | J:177769 Aebischer J, Sturny R, Andrieu D, Rieusset A, Schaller F, Geib S, Raoul C, Muscatelli F, Necdin protects embryonic motoneurons from programmed cell death. PLoS One. 2011;6(9):e23764 |
1* | J:315590 Fujiwara K, Hasegawa K, Oka M, Yoneda Y, Yoshikawa K, Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system. Genes Cells. 2016 Nov;21(11):1176-1194 |
3 | J:294283 Liang Q, Zheng Q, Zuo Y, Chen Y, Ma J, Ni P, Cheng J, SENP2 Suppresses Necdin Expression to Promote Brown Adipocyte Differentiation. Cell Rep. 2019 Aug 20;28(8):2004-2011.e4 |
1 | J:132276 Zanella S, Watrin F, Mebarek S, Marly F, Roussel M, Gire C, Diene G, Tauber M, Muscatelli F, Hilaire G, Necdin plays a role in the serotonergic modulation of the mouse respiratory network: implication for Prader-Willi syndrome. J Neurosci. 2008 Feb 13;28(7):1745-55 |
Ndnf neuron-derived neurotrophic factor (Synonyms: A930038C07Rik, epidermacan) | |
Results | Reference |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:281878 Yook C, Kim K, Kim D, Kang H, Kim SG, Kim E, Kim SY, A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice. Front Mol Neurosci. 2019;12:241 |
Ndrg1 N-myc downstream regulated gene 1 (Synonyms: CAP43, CMT4D, DRG1, Ndr1, Ndrl, PROXY1, Tdd5, TDD5) | |
Results | Reference |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
1* | J:56022 Shimono A, Okuda T, Kondoh H, N-myc-dependent repression of ndr1, a gene identified by direct subtraction of whole mouse embryo cDNAs between wild type and N-myc mutant. Mech Dev. 1999 May;83(1-2):39-52 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Ndrg2 N-myc downstream regulated gene 2 (Synonyms: Ndr2) | |
Results | Reference |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
1* | J:181235 Liu L, Shi M, Wang L, Hou S, Wu Z, Zhao G, Deng Y, Ndrg2 expression in neurogenic germinal zones of embryonic and postnatal mouse brain. J Mol Histol. 2012 Feb;43(1):27-35 |
Ndst1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1 (Synonyms: 1200015G06Rik, b2b2230Clo, glucosaminyl N-deacetylase/N-sulfotransferase 1, Hsst, Ndst-1) | |
Results | Reference |
1 | J:100425 Grobe K, Inatani M, Pallerla SR, Castagnola J, Yamaguchi Y, Esko JD, Cerebral hypoplasia and craniofacial defects in mice lacking heparan sulfate Ndst1 gene function. Development. 2005 Aug;132(16):3777-86 |
Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 (Synonyms: 1810049F12Rik, MWFE) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
Ndufaf7 NADH:ubiquinone oxidoreductase complex assembly factor 7 (Synonyms: 2410091C18Rik) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Ndufb8 NADH:ubiquinone oxidoreductase subunit B8 (Synonyms: 2900010I05Rik) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
1 | J:337469 Park A, Kim KE, Park I, Lee SH, Park KY, Jung M, Li X, Sleiman MB, Lee SJ, Kim DS, Kim J, Lim DS, Woo EJ, Lee EW, Han BS, Oh KJ, Lee SC, Auwerx J, Mun JY, Rhee HW, Kim WK, Bae KH, Suh JM, Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice. Nat Commun. 2023 Jun 23;14(1):3746 |
1* | J:305946 Xu M, Yao J, Shi Y, Yi H, Zhao W, Lin X, Yang Z, The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026 |
Ndufb11 NADH:ubiquinone oxidoreductase subunit B11 (Synonyms: D5Bwg0566e, D5Bwg0577e, Np15) | |
Results | Reference |
1* | J:116142 Gurok U, Bork K, Nuber U, Sporle R, Nohring S, Horstkorte R, Expression of Ndufb11 encoding the neuronal protein 15.6 during neurite outgrowth and development. Gene Expr Patterns. 2007 Jan;7(3):370-4 |
Ndufs8 NADH:ubiquinone oxidoreductase core subunit S8 | |
Results | Reference |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
Necab2 N-terminal EF-hand calcium binding protein 2 (Synonyms: Efcbp2, Necab2) | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Nectin1 nectin cell adhesion molecule 1 (Synonyms: Cd111, HIgR, HveC, nectin-1, PRR, PRR1, Pvrl1) | |
Results | Reference |
1 | J:198427 Dudok JJ, Sanz AS, Lundvig DM, Wijnholds J, MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. J Neurosci. 2013 May 8;33(19):8518-27 |
1 | J:206576 Fukuda T, Kominami K, Wang S, Togashi H, Hirata K, Mizoguchi A, Rikitake Y, Takai Y, Aberrant cochlear hair cell attachments caused by Nectin-3 deficiency result in hair bundle abnormalities. Development. 2014 Jan;141(2):399-409 |
1 | J:101707 Inagaki M, Irie K, Ishizaki H, Tanaka-Okamoto M, Morimoto K, Inoue E, Ohtsuka T, Miyoshi J, Takai Y, Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development. Development. 2005 Apr;132(7):1525-37 |
2 | J:321073 Mollo MR, Antonini D, Mitchell K, Fortugno P, Costanzo A, Dixon J, Brancati F, Missero C, p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis. Exp Dermatol. 2015 Feb;24(2):114-9 |
2 | J:90052 Okabe N, Ozaki-Kuroda K, Nakanishi H, Shimizu K, Takai Y, Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo. Dev Dyn. 2004 May;230(1):174-86 |
1 | J:93147 Okabe N, Shimizu K, Ozaki-Kuroda K, Nakanishi H, Morimoto K, Takeuchi M, Katsumaru H, Murakami F, Takai Y, Contacts between the commissural axons and the floor plate cells are mediated by nectins. Dev Biol. 2004 Sep 15;273(2):244-56 |
Nectin2 nectin cell adhesion molecule 2 (Synonyms: Cd112, MPH, nectin-2, Pvrl2, Pvs) | |
Results | Reference |
1 | J:101707 Inagaki M, Irie K, Ishizaki H, Tanaka-Okamoto M, Morimoto K, Inoue E, Ohtsuka T, Miyoshi J, Takai Y, Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development. Development. 2005 Apr;132(7):1525-37 |
1 | J:321073 Mollo MR, Antonini D, Mitchell K, Fortugno P, Costanzo A, Dixon J, Brancati F, Missero C, p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis. Exp Dermatol. 2015 Feb;24(2):114-9 |
2 | J:90052 Okabe N, Ozaki-Kuroda K, Nakanishi H, Shimizu K, Takai Y, Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo. Dev Dyn. 2004 May;230(1):174-86 |
1* | J:165548 Yoshida T, Miyoshi J, Takai Y, Thesleff I, Cooperation of nectin-1 and nectin-3 is required for normal ameloblast function and crown shape development in mouse teeth. Dev Dyn. 2010 Oct;239(10):2558-69 |
Nectin3 nectin cell adhesion molecule 3 (Synonyms: 2610301B19Rik, 3000002N23Rik, 4921513D19Rik, nectin-3, Pvrl3) | |
Results | Reference |
1 | J:101707 Inagaki M, Irie K, Ishizaki H, Tanaka-Okamoto M, Morimoto K, Inoue E, Ohtsuka T, Miyoshi J, Takai Y, Roles of cell-adhesion molecules nectin 1 and nectin 3 in ciliary body development. Development. 2005 Apr;132(7):1525-37 |
1 | J:321073 Mollo MR, Antonini D, Mitchell K, Fortugno P, Costanzo A, Dixon J, Brancati F, Missero C, p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis. Exp Dermatol. 2015 Feb;24(2):114-9 |
1 | J:90052 Okabe N, Ozaki-Kuroda K, Nakanishi H, Shimizu K, Takai Y, Expression patterns of nectins and afadin during epithelial remodeling in the mouse embryo. Dev Dyn. 2004 May;230(1):174-86 |
1 | J:93147 Okabe N, Shimizu K, Ozaki-Kuroda K, Nakanishi H, Morimoto K, Takeuchi M, Katsumaru H, Murakami F, Takai Y, Contacts between the commissural axons and the floor plate cells are mediated by nectins. Dev Biol. 2004 Sep 15;273(2):244-56 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Nectin4 nectin cell adhesion molecule 4 (Synonyms: 1200017F15Rik, nectin 4, Prr4, Pvrl4) | |
Results | Reference |
1* | J:169190 Brancati F, Fortugno P, Bottillo I, Lopez M, Josselin E, Boudghene-Stambouli O, Agolini E, Bernardini L, Bellacchio E, Iannicelli M, Rossi A, Dib-Lachachi A, Stuppia L, Palka G, Mundlos S, Stricker S, Kornak U, Zambruno G, Dallapiccola B, Mutations in PVRL4, encoding cell adhesion molecule nectin-4, cause ectodermal dysplasia-syndactyly syndrome. Am J Hum Genet. 2010 Aug 13;87(2):265-73 |
1 | J:321073 Mollo MR, Antonini D, Mitchell K, Fortugno P, Costanzo A, Dixon J, Brancati F, Missero C, p63-dependent and independent mechanisms of nectin-1 and nectin-4 regulation in the epidermis. Exp Dermatol. 2015 Feb;24(2):114-9 |
1* | J:165548 Yoshida T, Miyoshi J, Takai Y, Thesleff I, Cooperation of nectin-1 and nectin-3 is required for normal ameloblast function and crown shape development in mouse teeth. Dev Dyn. 2010 Oct;239(10):2558-69 |
Nedd4 neural precursor cell expressed, developmentally down-regulated 4 (Synonyms: E430025J12Rik, mKIAA0093, Nedd4, Nedd4-1, Nedd4a) | |
Results | Reference |
1* | J:149227 Liu Y, Oppenheim RW, Sugiura Y, Lin W, Abnormal development of the neuromuscular junction in Nedd4-deficient mice. Dev Biol. 2009 Jun 1;330(1):153-66 |
Nedd8 neural precursor cell expressed, developmentally down-regulated gene 8 (Synonyms: Rub1) | |
Results | Reference |
1* | J:90626 Carrabino S, Carminati E, Talarico D, Pardi R, Bianchi E, Expression pattern of the JAB1/CSN5 gene during murine embryogenesis: colocalization with NEDD8. Gene Expr Patterns. 2004 Jul;4(4):423-31 |
Nedd9 neural precursor cell expressed, developmentally down-regulated gene 9 (Synonyms: Cas-L, CasL, E230025G09Rik, HEF1) | |
Results | Reference |
1 | J:317613 Patnaik SR, Kretschmer V, Brucker L, Schneider S, Volz AK, Oancea-Castillo LDR, May-Simera HL, Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation. Cell Mol Life Sci. 2019 Feb;76(4):757-775 |
1 | J:339438 Wong W, Estep JA, Treptow AM, Rajabli N, Jahncke JN, Ubina T, Wright KM, Riccomagno MM, An adhesion signaling axis involving Dystroglycan, beta1-Integrin, and Cas adaptor proteins regulates the establishment of the cortical glial scaffold. PLoS Biol. 2023 Aug;21(8):e3002212 |
Nefh neurofilament, heavy polypeptide (Synonyms: mKIAA0845, NEFH, NF200, NF-H) | |
Results | Reference |
1* | J:202451 Del Rio T, Nishitani AM, Yu WM, Goodrich LV, In vivo analysis of lrig genes reveals redundant and independent functions in the inner ear. PLoS Genet. 2013 Sep;9(9):e1003824 |
1 | J:54791 Faussone-Pellegrini MS, Matini P, DeFelici M, The cytoskeleton of the myenteric neurons during murine embryonic life. Anat Embryol (Berl). 1999 May;199(5):459-69 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1 | J:48411 Howard MJ, Gershon MD, Development of LBP110 expression by neural crest-derived enteric precursors: migration and differentiation potential in ls/ls mutant mice. J Neurobiol. 1998 Jun 15;35(4):341-54 |
1 | J:173361 Itoh A, Horiuchi M, Wakayama K, Xu J, Bannerman P, Pleasure D, Itoh T, ZPK/DLK, a mitogen-activated protein kinase kinase kinase, is a critical mediator of programmed cell death of motoneurons. J Neurosci. 2011 May 18;31(20):7223-8 |
1 | J:275123 Jenkins BA, Fontecilla NM, Lu CP, Fuchs E, Lumpkin EA, The cellular basis of mechanosensory Merkel-cell innervation during development. Elife. 2019 Feb 22;8:e42633 |
1 | J:279675 Jones I, Hagglund AC, Carlsson L, Reduced mTORC1-signalling in retinal progenitor cells leads to visual pathway dysfunction. Biol Open. 2019 Aug 1;8(8):bio044370 |
1 | J:249035 Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M, McGillewie L, Bar S, Minocha S, Chevalier C, Po C, Chelly J, Mandel JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, Herault Y, Collins SC, Friant S, Godin JD, Yalcin B, WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9308-E9317 |
1 | J:297711 Kaplan MM, Flucher BE, Postsynaptic CaV1.1-driven calcium signaling coordinates presynaptic differentiation at the developing neuromuscular junction. Sci Rep. 2019 Dec 5;9(1):18450 |
1 | J:270927 Kridsada K, Niu J, Haldipur P, Wang Z, Ding L, Li JJ, Lindgren AG, Herrera E, Thomas GM, Chizhikov VV, Millen KJ, Luo W, Roof Plate-Derived Radial Glial-like Cells Support Developmental Growth of Rapidly Adapting Mechanoreceptor Ascending Axons. Cell Rep. 2018 Jun 5;23(10):2928-2941 |
1 | J:175241 Mohseni P, Sung HK, Murphy AJ, Laliberte CL, Pallari HM, Henkelman M, Georgiou J, Xie G, Quaggin SE, Thorner PS, Eriksson JE, Nagy A, Nestin Is Not Essential for Development of the CNS But Required for Dispersion of Acetylcholine Receptor Clusters at the Area of Neuromuscular Junctions. J Neurosci. 2011 Aug 10;31(32):11547-11552 |
1 | J:231738 Reed-Geaghan EG, Wright MC, See LA, Adelman PC, Lee KH, Koerber HR, Maricich SM, Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. J Neurosci. 2016 Apr 13;36(15):4362-76 |
1 | J:108169 Ruan HZ, Moules E, Burnstock G, Changes in P2X3 purinoceptors in sensory ganglia of the mouse during embryonic and postnatal development. Histochem Cell Biol. 2004 Dec;122(6):539-51 |
1 | J:73913 Tisay KT, St John JA, Key B, Expression of specific glycoconjugates in both primary and secondary olfactory pathways in BALB/C mice. J Comp Neurol. 2002 Feb 11;443(3):213-25 |
1 | J:302429 Wang Z, Jung JS, Inbar TC, Rangoussis KM, Faaborg-Andersen C, Coate TM, The Purinergic Receptor P2rx3 is Required for Spiral Ganglion Neuron Branch Refinement during Development. eNeuro. 2020 Jul/Aug;7(4):ENEURO.0179-20.2020 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
1 | J:181187 Woo SH, Baba Y, Franco AM, Lumpkin EA, Owens DM, Excitatory glutamate is essential for development and maintenance of the piloneural mechanoreceptor. Development. 2012 Feb;139(4):740-8 |
1 | J:185531 Wu H, Lu Y, Barik A, Joseph A, Taketo MM, Xiong WC, Mei L, beta-Catenin gain of function in muscles impairs neuromuscular junction formation. Development. 2012 Jul;139(13):2392-404 |
Nefl neurofilament, light polypeptide (Synonyms: CMT2E, NF68, Nfl, NF-L) | |
Results | Reference |
1 | J:226819 Coate TM, Spita NA, Zhang KD, Isgrig KT, Kelley MW, Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife. 2015;4 |
1 | J:54791 Faussone-Pellegrini MS, Matini P, DeFelici M, The cytoskeleton of the myenteric neurons during murine embryonic life. Anat Embryol (Berl). 1999 May;199(5):459-69 |
1 | J:48411 Howard MJ, Gershon MD, Development of LBP110 expression by neural crest-derived enteric precursors: migration and differentiation potential in ls/ls mutant mice. J Neurobiol. 1998 Jun 15;35(4):341-54 |
1 | J:208050 Huang TN, Chuang HC, Chou WH, Chen CY, Wang HF, Chou SJ, Hsueh YP, Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality. Nat Neurosci. 2014 Feb;17(2):240-7 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
2 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:201069 Stubbusch J, Narasimhan P, Huber K, Unsicker K, Rohrer H, Ernsberger U, Synaptic protein and pan-neuronal gene expression and their regulation by Dicer-dependent mechanisms differ between neurons and neuroendocrine cells. Neural Dev. 2013 Aug 20;8(1):16 |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
1 | J:73779 Wang SW, Mu X, Bowers WJ, Kim DS, Plas DJ, Crair MC, Federoff HJ, Gan L, Klein WH, Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth. Development. 2002 Jan;129(2):467-77 |
1* | J:16894 Yamagata T, Momoi MY, Yanagisawa M, Kumagai H, Yamakado M, Momoi T, Changes of the expression and distribution of retinoic acid receptors during neurogenesis in mouse embryos. Brain Res Dev Brain Res. 1994 Feb 18;77(2):163-76 |
Nefm neurofilament, medium polypeptide (Synonyms: Nef3, neurofilament-M, NF160, NF165, Nfm, NF-M) | |
Results | Reference |
1 | J:310063 Balendran V, Skidmore JM, Ritter KE, Gao J, Cimerman J, Beyer LA, Hurd EA, Raphael Y, Martin DM, Chromatin remodeler CHD7 is critical for cochlear morphogenesis and neurosensory patterning. Dev Biol. 2021 Sep;477:11-21 |
1 | J:171672 Cheever TR, Olson EA, Ervasti JM, Axonal regeneration and neuronal function are preserved in motor neurons lacking ss-actin in vivo. PLoS One. 2011;6(3):e17768 |
1* | J:313926 Cichon MA, Klas K, Buchberger M, Hammer M, Sere K, Zenke M, Tschachler E, Elbe-Burger A, Distinct Distribution of RTN1A in Immune Cells in Mouse Skin and Lymphoid Organs. Front Cell Dev Biol. 2020;8:608876 |
1 | J:248927 Clements R, Turk R, Campbell KP, Wright KM, Dystroglycan Maintains Inner Limiting Membrane Integrity to Coordinate Retinal Development. J Neurosci. 2017 Aug 30;37(35):8559-8574 |
1* | J:332642 Cohen-Gulkar M, David A, Messika-Gold N, Eshel M, Ovadia S, Zuk-Bar N, Idelson M, Cohen-Tayar Y, Reubinoff B, Ziv T, Shamay M, Elkon R, Ashery-Padan R, The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration. PLoS Biol. 2023 Jan;21(1):e3001924 |
1 | J:252860 Dorninger F, Herbst R, Kravic B, Camurdanoglu BZ, Macinkovic I, Zeitler G, Forss-Petter S, Strack S, Khan MM, Waterham HR, Rudolf R, Hashemolhosseini S, Berger J, Reduced muscle strength in ether lipid-deficient mice is accompanied by altered development and function of the neuromuscular junction. J Neurochem. 2017 Dec;143(5):569-583 |
1 | J:249229 Espinosa-Medina I, Outin E, Picard CA, Chettouh Z, Dymecki S, Consalez GG, Coppola E, Brunet JF, Neurodevelopment. Parasympathetic ganglia derive from Schwann cell precursors. Science. 2014 Jul 4;345(6192):87-90 |
1 | J:54791 Faussone-Pellegrini MS, Matini P, DeFelici M, The cytoskeleton of the myenteric neurons during murine embryonic life. Anat Embryol (Berl). 1999 May;199(5):459-69 |
1 | J:250440 Ferguson R, Serafeimidou-Pouliou E, Subramanian V, Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation. J Anat. 2016 Dec;229(6):871-891 |
1 | J:284934 Findlay AS, McKie L, Keighren M, Clementson-Mobbs S, Sanchez-Pulido L, Wells S, Cross SH, Jackson IJ, Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function. Sci Rep. 2020 Jan 16;10(1):437 |
1 | J:223161 Gahring LC, Myers E, Palumbos S, Rogers SW, Nicotinic receptor Alpha7 expression during mouse adrenal gland development. PLoS One. 2014;9(8):e103861 |
1 | J:266784 Gay MH, Valenta T, Herr P, Paratore-Hari L, Basler K, Sommer L, Distinct adhesion-independent functions of beta-catenin control stage-specific sensory neurogenesis and proliferation. BMC Biol. 2015 Apr 11;13:24 |
1* | J:137254 Harrison SJ, Parrish M, Monaghan AP, Sall3 is required for the terminal maturation of olfactory glomerular interneurons. J Comp Neurol. 2008 Apr 10;507(5):1780-94 |
1 | J:80082 Herbst R, Avetisova E, Burden SJ, Restoration of synapse formation in Musk mutant mice expressing a Musk/Trk chimeric receptor. Development. 2002 Dec;129(23):5449-60 |
1* | J:85445 Herrera E, Brown L, Aruga J, Rachel RA, Dolen G, Mikoshiba K, Brown S, Mason CA, Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell. 2003 Sep 5;114(5):545-57 |
1 | J:48411 Howard MJ, Gershon MD, Development of LBP110 expression by neural crest-derived enteric precursors: migration and differentiation potential in ls/ls mutant mice. J Neurobiol. 1998 Jun 15;35(4):341-54 |
1 | J:212111 Hua ZL, Jeon S, Caterina MJ, Nathans J, Frizzled3 is required for the development of multiple axon tracts in the mouse central nervous system. Proc Natl Acad Sci U S A. 2014 Jul 22;111(29):E3005-14 |
1 | J:70744 Huang EJ, Liu W, Fritzsch B, Bianchi LM, Reichardt LF, Xiang M, Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons. Development. 2001 Jul;128(13):2421-32 |
1* | J:54064 Kablar B, Rudnicki MA, Development in the absence of skeletal muscle results in the sequential ablation of motor neurons from the spinal cord to the brain. Dev Biol. 1999 Apr 1;208(1):93-109 |
1 | J:249035 Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M, McGillewie L, Bar S, Minocha S, Chevalier C, Po C, Chelly J, Mandel JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, Herault Y, Collins SC, Friant S, Godin JD, Yalcin B, WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9308-E9317 |
1 | J:338359 Kaur N, Han W, Li Z, Madrigal MP, Shim S, Pochareddy S, Gulden FO, Li M, Xu X, Xing X, Takeo Y, Li Z, Lu K, Imamura Kawasawa Y, Ballester-Lurbe B, Moreno-Bravo JA, Chedotal A, Terrado J, Perez-Roger I, Koleske AJ, Sestan N, Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold. Neuron. 2020 Sep 23;107(6):1197-1211.e9 |
1 | J:169455 Kim D, Ackerman SL, The UNC5C netrin receptor regulates dorsal guidance of mouse hindbrain axons. J Neurosci. 2011 Feb 9;31(6):2167-79 |
1 | J:100207 Kobayashi K, Takahashi M, Matsushita N, Miyazaki J, Koike M, Yaginuma H, Osumi N, Kaibuchi K, Kobayashi K, Survival of developing motor neurons mediated by Rho GTPase signaling pathway through Rho-kinase. J Neurosci. 2004 Apr 7;24(14):3480-8 |
1* | J:127447 Kwiatkowski AV, Rubinson DA, Dent EW, Edward van Veen J, Leslie JD, Zhang J, Mebane LM, Philippar U, Pinheiro EM, Burds AA, Bronson RT, Mori S, Fassler R, Gertler FB, Ena/VASP Is Required for neuritogenesis in the developing cortex. Neuron. 2007 Nov 8;56(3):441-55 |
1* | J:73497 Lawoko-Kerali G, Rivolta MN, Holley M, Expression of the transcription factors GATA3 and Pax2 during development of the mammalian inner ear. J Comp Neurol. 2002 Jan 21;442(4):378-91 |
1 | J:241012 Lee M, Yoon J, Song H, Lee B, Lam DT, Yoon J, Baek K, Clevers H, Jeong Y, Tcf7l2 plays crucial roles in forebrain development through regulation of thalamic and habenular neuron identity and connectivity. Dev Biol. 2017 Apr 01;424(1):62-76 |
1 | J:273013 Lee MA, Sitko AA, Khalid S, Shirasu-Hiza M, Mason CA, Spatiotemporal distribution of glia in and around the developing mouse optic tract. J Comp Neurol. 2019 Feb 15;527(3):508-521 |
1 | J:99854 Lin W, Dominguez B, Yang J, Aryal P, Brandon EP, Gage FH, Lee KF, Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism. Neuron. 2005 May 19;46(4):569-79 |
1 | J:273796 Liu Y, Sugiura Y, Chen F, Lee KF, Ye Q, Lin W, Blocking skeletal muscle DHPRs/Ryr1 prevents neuromuscular synapse loss in mutant mice deficient in type III Neuregulin 1 (CRD-Nrg1). PLoS Genet. 2019 Mar;15(3):e1007857 |
1 | J:208651 Louvi A, Nishimura S, Gunel M, Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration. Development. 2014 Mar;141(6):1404-15 |
1 | J:123223 Markham K, Schuurmans C, Weiss S, STAT5A/B activity is required in the developing forebrain and spinal cord. Mol Cell Neurosci. 2007 Jun;35(2):272-82 |
1 | J:348685 Masuda A, Nishida K, Ajima R, Saga Y, Bakhtan M, Klar A, Hirata T, Zhu Y, A global gene regulatory program and its region-specific regulator partition neurons into commissural and ipsilateral projection types. Sci Adv. 2024 May 24;10(21):eadk2149 |
1* | J:148803 McCulloch DR, Le Goff C, Bhatt S, Dixon LJ, Sandy JD, Apte SS, Adamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues. Gene Expr Patterns. 2009 Jun;9(5):314-23 |
1 | J:104532 Mendes SW, Henkemeyer M, Liebl DJ, Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J Neurosci. 2006 Jan 18;26(3):882-92 |
1 | J:198637 Minchin JE, Williams VC, Hinits Y, Low S, Tandon P, Fan CM, Rawls JF, Hughes SM, Oesophageal and sternohyal muscle fibres are novel Pax3-dependent migratory somite derivatives essential for ingestion. Development. 2013 Jul;140(14):2972-84 |
1 | J:175241 Mohseni P, Sung HK, Murphy AJ, Laliberte CL, Pallari HM, Henkelman M, Georgiou J, Xie G, Quaggin SE, Thorner PS, Eriksson JE, Nagy A, Nestin Is Not Essential for Development of the CNS But Required for Dispersion of Acetylcholine Receptor Clusters at the Area of Neuromuscular Junctions. J Neurosci. 2011 Aug 10;31(32):11547-11552 |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
1 | J:170647 Mundell NA, Labosky PA, Neural crest stem cell multipotency requires Foxd3 to maintain neural potential and repress mesenchymal fates. Development. 2011 Feb;138(4):641-52 |
1 | J:296800 Munezane H, Oizumi H, Wakabayashi T, Nishio S, Hirasawa T, Sato T, Harada A, Yoshida T, Eguchi T, Yamanashi Y, Hashimoto T, Iwatsubo T, Roles of Collagen XXV and Its Putative Receptors PTPsigma/delta in Intramuscular Motor Innervation and Congenital Cranial Dysinnervation Disorder. Cell Rep. 2019 Dec 24;29(13):4362-4376.e6 |
1 | J:143162 Murata J, Tokunaga A, Okano H, Kubo T, Mapping of notch activation during cochlear development in mice: implications for determination of prosensory domain and cell fate diversification. J Comp Neurol. 2006 Jul 20;497(3):502-18 |
1* | J:102348 Nery S, Corbin JG, Fishell G, Dlx2 progenitor migration in wild type and Nkx2.1 mutant telencephalon. Cereb Cortex. 2003 Sep;13(9):895-903 |
1 | J:207212 Oh WJ, Gu C, Establishment of neurovascular congruency in the mouse whisker system by an independent patterning mechanism. Neuron. 2013 Oct 16;80(2):458-69 |
1 | J:143441 Okamura Y, Saga Y, Notch signaling is required for the maintenance of enteric neural crest progenitors. Development. 2008 Nov;135(21):3555-65 |
1 | J:221584 Quesnel-Vallieres M, Irimia M, Cordes SP, Blencowe BJ, Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development. Genes Dev. 2015 Apr 1;29(7):746-59 |
1 | J:93814 Reddy T, Kablar B, Evidence for the involvement of neurotrophins in muscle transdifferentiation and acetylcholine receptor transformation in the esophagus of Myf5(-/-):MyoD(-/-) and NT-3(-/-) embryos. Dev Dyn. 2004 Dec;231(4):683-92 |
1 | J:43515 Riethmacher D, Sonnenberg-Riethmacher E, Brinkmann V, Yamaai T , Lewin GR , Birchmeier C, Severe neuropathies in mice with targeted mutations in the ErbB3 receptor. Nature. 1997 Oct 16;389(6652):725-30 |
1 | J:246732 Saller MM, Huettl RE, Hanuschick P, Amend AL, Alberton P, Aszodi A, Huber AB, The role of Sema3-Npn-1 signaling during diaphragm innervation and muscle development. J Cell Sci. 2016 Sep 01;129(17):3295-308 |
1* | J:70492 Shu T, Shen WB, Richards LJ, Development of the perforating pathway: an ipsilaterally projecting pathway between the medial septum/diagonal band of Broca and the cingulate cortex that intersects the corpus callosum. J Comp Neurol. 2001 Aug 6;436(4):411-22 |
1* | J:324710 Stanton-Turcotte D, Hsu K, Moore SA, Yamada M, Fawcett JP, Iulianella A, Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development. J Neurosci. 2022 May 11;42(19):3931-3948 |
1 | J:201069 Stubbusch J, Narasimhan P, Huber K, Unsicker K, Rohrer H, Ernsberger U, Synaptic protein and pan-neuronal gene expression and their regulation by Dicer-dependent mechanisms differ between neurons and neuroendocrine cells. Neural Dev. 2013 Aug 20;8(1):16 |
1 | J:98330 Suto F, Ito K, Uemura M, Shimizu M, Shinkawa Y, Sanbo M, Shinoda T, Tsuboi M, Takashima S, Yagi T, Fujisawa H, Plexin-a4 mediates axon-repulsive activities of both secreted and transmembrane semaphorins and plays roles in nerve fiber guidance. J Neurosci. 2005 Apr 6;25(14):3628-37 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
1 | J:116994 Winseck AK, Oppenheim RW, An in vivo analysis of Schwann cell programmed cell death in embryonic mice: the role of axons, glial growth factor, and the pro-apoptotic gene Bax. Eur J Neurosci. 2006 Oct;24(8):2105-17 |
1 | J:69623 Yang X, Arber S, William C, Li L, Tanabe Y, Jessell TM, Birchmeier C, Burden SJ, Patterning of muscle acetylcholine receptor gene expression in the absence of motor innervation. Neuron. 2001 May;30(2):399-410 |
1 | J:143763 Zhang Y, Singh MK, Degenhardt KR, Lu MM, Bennett J, Yoshida Y, Epstein JA, Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects. Dev Biol. 2009 Jan 1;325(1):82-93 |
1 | J:309104 Zheng MH, Shi M, Pei Z, Gao F, Han H, Ding YQ, The transcription factor RBP-J is essential for retinal cell differentiation and lamination. Mol Brain. 2009 Dec 18;2:38 |
1 | J:109778 Zhou CJ, Pinson KI, Pleasure SJ, Severe defects in dorsal thalamic development in low-density lipoprotein receptor-related protein-6 mutants. J Neurosci. 2004 Sep 1;24(35):7632-9 |
Negr1 neuronal growth regulator 1 (Synonyms: 5330422G01Rik, neurotractin, Ntra) | |
Results | Reference |
1* | J:312430 Fearnley S, Raja R, Cloutier JF, Spatiotemporal expression of IgLON family members in the developing mouse nervous system. Sci Rep. 2021 Oct 1;11(1):19536 |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Nek1 NIMA (never in mitosis gene a)-related expressed kinase 1 (Synonyms: D8Ertd790e, kat, kidney, anemia and testis) | |
Results | Reference |
1 | J:47160 Arama E, Yanai A, Kilfin G, Bernstein A, Motro B, Murine NIMA-related kinases are expressed in patterns suggesting distinct functions in gametogenesis and a role in the nervous system. Oncogene. 1998 Apr 9;16(14):1813-23 |
1* | J:215391 Chen Y, Chiang HC, Litchfield P, Pena M, Juang C, Riley DJ, Expression of Nek1 during kidney development and cyst formation in multiple nephron segments in the Nek1-deficient kat2J mouse model of polycystic kidney disease. J Biomed Sci. 2014 Jul 17;21(1):63 |
Nek2 NIMA (never in mitosis gene a)-related expressed kinase 2 | |
Results | Reference |
1 | J:41081 Rhee K, Wolgemuth DJ, The NIMA-related kinase 2, Nek2, is expressed in specific stages of the meiotic cell cycle and associates with meiotic chromosomes. Development. 1997 Jun;124(11):2167-77 |
Nek6 NIMA (never in mitosis gene a)-related expressed kinase 6 (Synonyms: 1300007C09Rik) | |
Results | Reference |
1* | J:73821 Feige E, Motro B, The related murine kinases, Nek6 and Nek7, display distinct patterns of expression. Mech Dev. 2002 Jan;110(1-2):219-23 |
Nek7 NIMA (never in mitosis gene a)-related expressed kinase 7 (Synonyms: 2810460C19Rik) | |
Results | Reference |
1* | J:73821 Feige E, Motro B, The related murine kinases, Nek6 and Nek7, display distinct patterns of expression. Mech Dev. 2002 Jan;110(1-2):219-23 |
Nek8 NIMA (never in mitosis gene a)-related expressed kinase 8 (Synonyms: 4632401F23Rik, b2b1449Clo) | |
Results | Reference |
1* | J:134562 Trapp ML, Galtseva A, Manning DK, Beier DR, Rosenblum ND, Quarmby LM, Defects in ciliary localization of Nek8 is associated with cystogenesis. Pediatr Nephrol. 2008 Mar;23(3):377-87 |
Nell1 NEL-like 1 (Synonyms: B230343H07Rik, l7R6) | |
Results | Reference |
1 | J:108241 Desai J, Shannon ME, Johnson MD, Ruff DW, Hughes LA, Kerley MK, Carpenter DA, Johnson DK, Rinchik EM, Culiat CT, Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects. Hum Mol Genet. 2006 Apr 15;15(8):1329-41 |
1* | J:223669 Pang S, Shen J, Liu Y, Chen F, Zheng Z, James AW, Hsu CY, Zhang H, Lee KS, Wang C, Li C, Chen X, Jia H, Zhang X, Soo C, Ting K, Proliferation and osteogenic differentiation of mesenchymal stem cells induced by a short isoform of NELL-1. Stem Cells. 2015 Mar;33(3):904-15 |
1* | J:195896 Tang R, Wang Q, Du J, Yang P, Wang X, Expression and localization of Nell-1 during murine molar development. J Mol Histol. 2013 Apr;44(2):175-81 |
2 | J:202215 Zhang X, Ting K, Bessette CM, Culiat CT, Sung SJ, Lee H, Chen F, Shen J, Wang JJ, Kuroda S, Soo C, Nell-1, a key functional mediator of Runx2, partially rescues calvarial defects in Runx2(+/-) mice. J Bone Miner Res. 2011 Apr;26(4):777-91 |
1 | J:202210 Zhang X, Ting K, Pathmanathan D, Ko T, Chen W, Chen F, Lee H, James AW, Siu RK, Shen J, Culiat CT, Soo C, Calvarial cleidocraniodysplasia-like defects with ENU-induced Nell-1 deficiency. J Craniofac Surg. 2012 Jan;23(1):61-6 |
Nell2 NEL-like 2 (Synonyms: A330108N19Rik, mel91) | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Nenf neuron derived neurotrophic factor (Synonyms: 1110060M21Rik, neudesin) | |
Results | Reference |
1* | J:109511 Kimura I, Konishi M, Miyake A, Fujimoto M, Itoh N, Neudesin, a secreted factor, promotes neural cell proliferation and neuronal differentiation in mouse neural precursor cells. J Neurosci Res. 2006 Jun;83(8):1415-24 |
Neo1 neogenin (Synonyms: 2610028H22Rik, D930014N22Rik, Igdcc2) | |
Results | Reference |
1* | J:62806 Gad JM, Keeling SL, Shu T, Richards LJ, Cooper HM, The spatial and temporal expression patterns of netrin receptors, DCC and neogenin, in the developing mouse retina. Exp Eye Res. 2000 Jun;70(6):711-22 |
1* | J:45336 Gad JM, Keeling SL, Wilks AF, Tan SS, Cooper HM, The expression patterns of guidance receptors, DCC and Neogenin, are spatially and temporally distinct throughout mouse embryogenesis. Dev Biol. 1997 Dec 15;192(2):258-73 |
3 | J:235517 Kam JW, Dumontier E, Baim C, Brignall AC, Mendes da Silva D, Cowan M, Kennedy TE, Cloutier JF, RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016 May 1;143(9):1534-46 |
1* | J:42348 Keeling SL, Gad JM, Cooper HM, Mouse Neogenin, a DCC-like molecule, has four splice variants and is expressed widely in the adult mouse and during embryogenesis. Oncogene. 1997 Aug 7;15(6):691-700 |
2 | J:305520 Robinson RA, Griffiths SC, van de Haar LL, Malinauskas T, van Battum EY, Zelina P, Schwab RA, Karia D, Malinauskaite L, Brignani S, van den Munkhof MH, Dudukcu O, De Ruiter AA, Van den Heuvel DMA, Bishop B, Elegheert J, Aricescu AR, Pasterkamp RJ, Siebold C, Simultaneous binding of Guidance Cues NET1 and RGM blocks extracellular NEO1 signaling. Cell. 2021 Apr 15;184(8):2103-2120.e31 |
2* | J:199400 van den Heuvel DM, Hellemons AJ, Pasterkamp RJ, Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain. PLoS One. 2013;8(2):e55828 |
1 | J:227692 van Erp S, van den Heuvel DM, Fujita Y, Robinson RA, Hellemons AJ, Adolfs Y, Van Battum EY, Blokhuis AM, Kuijpers M, Demmers JA, Hedman H, Hoogenraad CC, Siebold C, Yamashita T, Pasterkamp RJ, Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases. Dev Cell. 2015 Dec 7;35(5):537-52 |
Nepn nephrocan (Synonyms: 5730521E12Rik, Npn, periolin) | |
Results | Reference |
1* | J:284817 Addeo M, Buonaiuto S, Guerriero I, Amendola E, Visconte F, Marino A, De Angelis MT, Russo F, Roberto L, Marotta P, Russo NA, Iervolino A, Amodio F, De Felice M, Lucci V, Falco G, Insight into Nephrocan Function in Mouse Endoderm Patterning. Int J Mol Sci. 2019 Dec 18;21(1):8 |
1* | J:154372 Li X, Udager AM, Hu C, Qiao XT, Richards N, Gumucio DL, Dynamic patterning at the pylorus: Formation of an epithelial intestine-stomach boundary in late fetal life. Dev Dyn. 2009 Oct 29;238(12):3205-3217 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Nes nestin (Synonyms: ESTM46, Ifaprc2, Marc2, RC2) | |
Results | Reference |
1 | J:181188 Aoki H, Hara A, Era T, Kunisada T, Yamada Y, Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development. 2012 Feb;139(4):667-77 |
1 | J:269647 Baizabal JM, Mistry M, Garcia MT, Gomez N, Olukoya O, Tran D, Johnson MB, Walsh CA, Harwell CC, The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position. Neuron. 2018 Jun 6;98(5):945-962.e8 |
1* | J:229480 Baker JL, Wood B, Karpinski BA, LaMantia AS, Maynard TM, Testicular receptor 2, Nr2c1, is associated with stem cells in the developing olfactory epithelium and other cranial sensory and skeletal structures. Gene Expr Patterns. 2016 Jan;20(1):71-9 |
1* | J:142365 Barry G, Piper M, Lindwall C, Moldrich R, Mason S, Little E, Sarkar A, Tole S, Gronostajski RM, Richards LJ, Specific glial populations regulate hippocampal morphogenesis. J Neurosci. 2008 Nov 19;28(47):12328-40 |
1 | J:40497 Blackshear PJ, Silver J, Nairn AC, Sulik KK, Squier MV, Stumpo DJ , Tuttle JS, Widespread neuronal ectopia associated with secondary defects in cerebrocortical chondroitin sulfate proteoglycans and basal lamina in MARCKS-deficient mice. Exp Neurol. 1997 May;145(1):46-61 |
1 | J:316182 Blume M, Inoguchi F, Sugiyama T, Owada Y, Osumi N, Aimi Y, Taki K, Katsuyama Y, Dab1 contributes differently to the morphogenesis of the hippocampal subdivisions. Dev Growth Differ. 2017 Oct;59(8):657-673 |
1 | J:187211 Bribian A, Fontana X, Llorens F, Gavin R, Reina M, Garcia-Verdugo JM, Torres JM, de Castro F, del Rio JA, Role of the cellular prion protein in oligodendrocyte precursor cell proliferation and differentiation in the developing and adult mouse CNS. PLoS One. 2012;7(4):e33872 |
1* | J:65296 Brouns MR, Matheson SF, Hu K, Delalle I, Caviness VS, Silver J, Bronson RT, Settleman J, The adhesion signaling molecule p190 RhoGAP is required for morphogenetic processes in neural development. Development. 2000 Nov;127(22):4891-903 |
1 | J:112971 Camarero G, Tyrsin OY, Xiang C, Pfeiffer V, Pleiser S, Wiese S, Gotz R, Rapp UR, Cortical migration defects in mice expressing A-RAF from the B-RAF locus. Mol Cell Biol. 2006 Oct;26(19):7103-15 |
1 | J:73073 Chapouton P, Schuurmans C, Guillemot F, Gotz M, The transcription factor neurogenin 2 restricts cell migration from the cortex to the striatum. Development. 2001 Dec;128(24):5149-59 |
1 | J:112200 Chen J, Boyle S, Zhao M, Su W, Takahashi K, Davis L, Decaestecker M, Takahashi T, Breyer MD, Hao CM, Differential expression of the intermediate filament protein nestin during renal development and its localization in adult podocytes. J Am Soc Nephrol. 2006 May;17(5):1283-91 |
1 | J:282264 Chen P, Zhang T, Yuan Z, Shen B, Chen L, Expression of the RNA methyltransferase Nsun5 is essential for developing cerebral cortex. Mol Brain. 2019 Aug 28;12(1):74 |
1 | J:301138 Chen SH, Lu CH, Tsai MJ, TCTP is Essential for Cell Proliferation and Survival during CNS Development. Cells. 2020 Jan 6;9(1):133 |
2 | J:102162 Cicero S, Herrup K, Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci. 2005 Oct 19;25(42):9658-68 |
1 | J:171179 d'Amora M, Angelini C, Marcoli M, Cervetto C, Kitada T, Vallarino M, Expression of PINK1 in the brain, eye and ear of mouse during embryonic development. J Chem Neuroanat. 2011 Mar;41(2):73-85 |
1 | J:353439 de Jaime-Soguero A, Hattemer J, Bufe A, Haas A, van den Berg J, van Batenburg V, Das B, di Marco B, Androulaki S, Bohly N, Landry JJM, Schoell B, Rosa VS, Villacorta L, Baskan Y, Trapp M, Benes V, Chabes A, Shahbazi M, Jauch A, Engel U, Patrizi A, Sotillo R, van Oudenaarden A, Bageritz J, Alfonso J, Bastians H, Acebron SP, Developmental signals control chromosome segregation fidelity during pluripotency and neurogenesis by modulating replicative stress. Nat Commun. 2024 Aug 28;15(1):7404 |
1 | J:329939 Everlien I, Yen TY, Liu YC, Di Marco B, Vazquez-Marin J, Centanin L, Alfonso J, Monyer H, Diazepam binding inhibitor governs neurogenesis of excitatory and inhibitory neurons during embryonic development via GABA signaling. Neuron. 2022 Oct 5;110(19):3139-3153.e6 |
1 | J:139119 Fan X, Kim HJ, Bouton D, Warner M, Gustafsson JA, Expression of liver X receptor beta is essential for formation of superficial cortical layers and migration of later-born neurons. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13445-50 |
1 | J:144651 Farkas LM, Haffner C, Giger T, Khaitovich P, Nowick K, Birchmeier C, Paabo S, Huttner WB, Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex. Neuron. 2008 Oct 9;60(1):40-55 |
1* | J:361965 Fujimoto T, Mori M, Tonosaki M, Yaoi T, Nakano K, Okamura T, Itoh K, Characterization of Dystrophin Dp71 Expression and Interaction Partners in Embryonic Brain Development: Implications for Duchenne/Becker Muscular Dystrophy. Mol Neurobiol. 2025 Jan 6; |
1* | J:315590 Fujiwara K, Hasegawa K, Oka M, Yoneda Y, Yoshikawa K, Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system. Genes Cells. 2016 Nov;21(11):1176-1194 |
1 | J:62563 Gaiano N, Nye JS, Fishell G, Radial glial identity is promoted by Notch1 signaling in the murine forebrain. Neuron. 2000 May;26(2):395-404 |
1 | J:163124 Galichet C, Lovell-Badge R, Rizzoti K, Nestin-Cre mice are affected by hypopituitarism, which is not due to significant activity of the transgene in the pituitary gland. PLoS One. 2010;5(7):e11443 |
1 | J:206763 Gan Q, Lee A, Suzuki R, Yamagami T, Stokes A, Nguyen BC, Pleasure D, Wang J, Chen HW, Zhou CJ, Pax6 mediates ss-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells. Stem Cells. 2014 Jan;32(1):45-58 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1* | J:283039 Giralt A, Brito V, Pardo M, Rubio SE, Marion-Poll L, Martin-Ibanez R, Zamora-Moratalla A, Bosch C, Ballesteros JJ, Blasco E, Garcia-Torralba A, Pascual M, Pumarola M, Alberch J, Gines S, Martin ED, Segovia J, Soriano E, Canals JM, Helios modulates the maturation of a CA1 neuronal subpopulation required for spatial memory formation. Exp Neurol. 2020 Jan;323:113095 |
1 | J:240770 Gobius I, Morcom L, Suarez R, Bunt J, Bukshpun P, Reardon W, Dobyns WB, Rubenstein JL, Barkovich AJ, Sherr EH, Richards LJ, Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum. Cell Rep. 2016 Oct 11;17(3):735-747 |
1* | J:308556 Goss G, Rognoni E, Salameti V, Watt FM, Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair. Front Cell Dev Biol. 2021;9:675080 |
1* | J:51429 Gotz M, Stoykova A, Gruss P, Pax6 controls radial glia differentiation in the cerebral cortex. Neuron. 1998 Nov;21(5):1031-44 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
1 | J:362521 Guo XL, Wang YD, Liu YJ, Chu L, Zhu H, Hu Y, Wu RY, Xie HY, Yu J, Li SP, Xiong CY, Li RY, Ke F, Chen L, Chen GQ, Chen L, Bai F, Enver T, Li GH, Li HF, Hong DL, Fetal hepatocytes protect the HSPC genome via fetuin-A. Nature. 2025 Jan;637(8045):402-411 |
1 | J:126335 Hack I, Hellwig S, Junghans D, Brunne B, Bock HH, Zhao S, Frotscher M, Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons. Development. 2007 Nov;134(21):3883-91 |
1* | J:84752 Hartfuss E, Forster E, Bock HH, Hack MA, Leprince P, Luque JM, Herz J, Frotscher M, Gotz M, Reelin signaling directly affects radial glia morphology and biochemical maturation. Development. 2003 Oct;130(19):4597-609 |
1 | J:67408 Hartfuss E, Galli R, Heins N, Gotz M, Characterization of CNS precursor subtypes and radial glia. Dev Biol. 2001 Jan 1;229(1):15-30 |
1 | J:119018 Haubst N, Georges-Labouesse E, De Arcangelis A, Mayer U, Gotz M, Basement membrane attachment is dispensable for radial glial cell fate and for proliferation, but affects positioning of neuronal subtypes. Development. 2006 Aug;133(16):3245-54 |
1 | J:250521 Hecht JH, Siegenthaler JA, Patterson KP, Pleasure SJ, Primary cellular meningeal defects cause neocortical dysplasia and dyslamination. Ann Neurol. 2010 Oct;68(4):454-64 |
1 | J:219839 Hirota Y, Kubo K, Katayama K, Honda T, Fujino T, Yamamoto TT, Nakajima K, Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex. J Comp Neurol. 2015 Feb 15;523(3):463-78 |
1 | J:166928 Hoeck JD, Jandke A, Blake SM, Nye E, Spencer-Dene B, Brandner S, Behrens A, Fbw7 controls neural stem cell differentiation and progenitor apoptosis via Notch and c-Jun. Nat Neurosci. 2010 Nov;13(11):1365-72 |
1 | J:276557 Hong GS, Lee SH, Lee B, Choi JH, Oh SJ, Jang Y, Hwang EM, Kim H, Jung J, Kim IB, Oh U, ANO1/TMEM16A regulates process maturation in radial glial cells in the developing brain. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12494-12499 |
1 | J:218888 Hong S, Song MR, Signal transducer and activator of transcription-3 maintains the stemness of radial glia at mid-neurogenesis. J Neurosci. 2015 Jan 21;35(3):1011-23 |
1 | J:186629 Huang X, Dubuc AM, Hashizume R, Berg J, He Y, Wang J, Chiang C, Cooper MK, Northcott PA, Taylor MD, Barnes MJ, Tihan T, Chen J, Hackett CS, Weiss WA, James CD, Rowitch DH, Shuman MA, Jan YN, Jan LY, Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics. Genes Dev. 2012 Aug 15;26(16):1780-96 |
1* | J:137733 Iguchi T, Sakata K, Yoshizaki K, Tago K, Mizuno N, Itoh H, Orphan G protein-coupled receptor GPR56 regulates neural progenitor cell migration via a G alpha 12/13 and Rho pathway. J Biol Chem. 2008 May 23;283(21):14469-78 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:334107 Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J, Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice. Hum Mol Genet. 2022 Oct 10;31(20):3504-3520 |
1* | J:347773 Kim HY, Kang B, Lee PR, Kim K, Hong GS, Expression patterns of Piezo1 in the developing mouse forebrain. Brain Struct Funct. 2024 Apr;229(3):759-773 |
1* | J:109511 Kimura I, Konishi M, Miyake A, Fujimoto M, Itoh N, Neudesin, a secreted factor, promotes neural cell proliferation and neuronal differentiation in mouse neural precursor cells. J Neurosci Res. 2006 Jun;83(8):1415-24 |
1* | J:127447 Kwiatkowski AV, Rubinson DA, Dent EW, Edward van Veen J, Leslie JD, Zhang J, Mebane LM, Philippar U, Pinheiro EM, Burds AA, Bronson RT, Mori S, Fassler R, Gertler FB, Ena/VASP Is Required for neuritogenesis in the developing cortex. Neuron. 2007 Nov 8;56(3):441-55 |
1 | J:317151 Lavado A, Gangwar R, Pare J, Wan S, Fan Y, Cao X, YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development. Dev Biol. 2021 Dec;480:39-49 |
1* | J:199301 Lavado A, He Y, Pare J, Neale G, Olson EN, Giovannini M, Cao X, Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34 |
1 | J:166777 Lavado A, Lagutin OV, Chow LM, Baker SJ, Oliver G, Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. PLoS Biol. 2010;8(8) |
1 | J:178674 Lavado A, Oliver G, Six3 is required for ependymal cell maturation. Development. 2011 Dec;138(24):5291-300 |
1 | J:178308 Lei J, Howard MJ, Targeted deletion of Hand2 in enteric neural precursor cells affects its functions in neurogenesis, neurotransmitter specification and gangliogenesis, causing functional aganglionosis. Development. 2011 Nov;138(21):4789-800 |
1 | J:87149 Li HS, Wang D, Shen Q, Schonemann MD, Gorski JA, Jones KR, Temple S, Jan LY, Jan YN, Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron. 2003 Dec 18;40(6):1105-18 |
1 | J:334530 Li SY, Bhandary B, Gu X, DeFalco T, Perivascular cells support folliculogenesis in the developing ovary. Proc Natl Acad Sci U S A. 2022 Oct 11;119(41):e2213026119 |
1 | J:302828 Liu R, Yang Y, Shen J, Chen H, Zhang Q, Ba R, Wei Y, Li KC, Zhang X, Zhao C, Fstl1 is involved in the regulation of radial glial scaffold development. Mol Brain. 2015 Sep 17;8:53 |
1 | J:208651 Louvi A, Nishimura S, Gunel M, Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration. Development. 2014 Mar;141(6):1404-15 |
1 | J:204170 Luccardini C, Hennekinne L, Viou L, Yanagida M, Murakami F, Kessaris N, Ma X, Adelstein RS, Mege RM, Metin C, N-cadherin sustains motility and polarity of future cortical interneurons during tangential migration. J Neurosci. 2013 Nov 13;33(46):18149-60 |
1 | J:170677 Malagelada C, Lopez-Toledano MA, Willett RT, Jin ZH, Shelanski ML, Greene LA, RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration. J Neurosci. 2011 Mar 2;31(9):3186-96 |
1 | J:316266 Martin-Ibanez R, Crespo E, Esgleas M, Urban N, Wang B, Waclaw R, Georgopoulos K, Martinez S, Campbell K, Vicario-Abejon C, Alberch J, Chan S, Kastner P, Rubenstein JL, Canals JM, Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons. Stem Cells Dev. 2012 Aug 10;21(12):2239-51 |
1 | J:341276 Matrongolo MJ, Ho-Nguyen KT, Jain M, Ang PS, Reddy A, Schaper S, Tischfield MA, Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice. Development. 2023 Sep 15;150(18):dev201381 |
1 | J:198698 Meng L, Lin T, Peng G, Hsu JK, Lee S, Lin SY, Tsai RY, Nucleostemin deletion reveals an essential mechanism that maintains the genomic stability of stem and progenitor cells. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11415-20 |
1 | J:70573 Misson JP, Edwards MA, Yamamoto M, Caviness VS Jr, Identification of radial glial cells within the developing murine central nervous system: studies based upon a new immunohistochemical marker. Brain Res Dev Brain Res. 1988 Nov 1;44(1):95-108 |
1 | J:34807 Miyata T, Nakajima K, Aruga J, Takahashi S, Ikenaka K, Mikoshiba K, Ogawa M, Distribution of a reeler gene-related antigen in the developing cerebellum: an immunohistochemical study with an allogeneic antibody CR-50 on normal and reeler mice. J Comp Neurol. 1996 Aug 19;372(2):215-28 |
1 | J:164005 Miyata T, Ono Y, Okamoto M, Masaoka M, Sakakibara A, Kawaguchi A, Hashimoto M, Ogawa M, Migration, early axonogenesis, and Reelin-dependent layer-forming behavior of early/posterior-born Purkinje cells in the developing mouse lateral cerebellum. Neural Dev. 2010;5:23 |
1 | J:132671 Moers A, Nurnberg A, Goebbels S, Wettschureck N, Offermanns S, Galpha12/Galpha13 deficiency causes localized overmigration of neurons in the developing cerebral and cerebellar cortices. Mol Cell Biol. 2008 Mar;28(5):1480-8 |
1 | J:304719 Morcom L, Gobius I, Marsh AP, Suarez R, Lim JW, Bridges C, Ye Y, Fenlon LR, Zagar Y, Douglass AM, Donahoo AL, Fothergill T, Shaikh S, Kozulin P, Edwards TJ, Cooper HM, Sherr EH, Chedotal A, Leventer RJ, Lockhart PJ, Richards LJ, DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation. Elife. 2021 Apr 19;10:e61769 |
1 | J:346596 Mubuchi A, Takechi M, Nishio S, Matsuda T, Itoh Y, Sato C, Kitajima K, Kitagawa H, Miyata S, Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons. Elife. 2024 Mar 21;12 |
1 | J:200905 Munoz DM, Singh S, Tung T, Agnihotri S, Nagy A, Guha A, Zadeh G, Hawkins C, Differential transformation capacity of neuro-glial progenitors during development. Proc Natl Acad Sci U S A. 2013 Aug 27;110(35):14378-83 |
1* | J:193587 Nakagawa E, Zhang L, Kim EJ, Shin JO, Cho SW, Ohshima H, Jung HS, The novel function of Oct3/4 in mouse tooth development. Histochem Cell Biol. 2012 Mar;137(3):367-76 |
1 | J:309437 Nakagawa N, Li J, Yabuno-Nakagawa K, Eom TY, Cowles M, Mapp T, Taylor R, Anton ES, APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017 Aug 15;31(16):1679-1692 |
1 | J:154587 Niquille M, Garel S, Mann F, Hornung JP, Otsmane B, Chevalley S, Parras C, Guillemot F, Gaspar P, Yanagawa Y, Lebrand C, Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C. PLoS Biol. 2009 Oct;7(10):e1000230 |
1* | J:98297 Ohta Y, Itoh K, Yaoi T, Tando S, Fukui K, Fushiki S, Spatiotemporal patterns of expression of IGSF4 in developing mouse nervous system. Brain Res Dev Brain Res. 2005 Apr 21;156(1):23-31 |
1 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:160038 Piper M, Moldrich RX, Lindwall C, Little E, Barry G, Mason S, Sunn N, Kurniawan ND, Gronostajski RM, Richards LJ, Multiple non-cell-autonomous defects underlie neocortical callosal dysgenesis in Nfib-deficient mice. Neural Dev. 2009;4:43 |
1* | J:98542 Rowan S, Cepko CL, A POU factor binding site upstream of the Chx10 homeobox gene is required for Chx10 expression in subsets of retinal progenitor cells and bipolar cells. Dev Biol. 2005 May 15;281(2):240-55 |
1 | J:269511 Roy A, Skibo J, Kalume F, Ni J, Rankin S, Lu Y, Dobyns WB, Mills GB, Zhao JJ, Baker SJ, Millen KJ, Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy. Elife. 2015 Dec 3;4:e12703 |
1 | J:109774 Roy K, Kuznicki K, Wu Q, Sun Z, Bock D, Schutz G, Vranich N, Monaghan AP, The Tlx gene regulates the timing of neurogenesis in the cortex. J Neurosci. 2004 Sep 22;24(38):8333-45 |
2 | J:205632 Saito A, Kanemoto S, Kawasaki N, Asada R, Iwamoto H, Oki M, Miyagi H, Izumi S, Sanosaka T, Nakashima K, Imaizumi K, Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun. 2012;3:967 |
1 | J:166208 Satz JS, Ostendorf AP, Hou S, Turner A, Kusano H, Lee JC, Turk R, Nguyen H, Ross-Barta SE, Westra S, Hoshi T, Moore SA, Campbell KP, Distinct functions of glial and neuronal dystroglycan in the developing and adult mouse brain. J Neurosci. 2010 Oct 27;30(43):14560-72 |
1 | J:213479 Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, Yoshida N, PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Cereb Cortex. 2013 Aug;23(8):1824-35 |
1* | J:77124 Shinozaki K, Miyagi T, Yoshida M, Miyata T, Ogawa M, Aizawa S, Suda Y, Absence of Cajal-Retzius cells and subplate neurons associated with defects of tangential cell migration from ganglionic eminence in Emx1/2 double mutant cerebral cortex. Development. 2002 Jul;129(14):3479-92 |
1* | J:324710 Stanton-Turcotte D, Hsu K, Moore SA, Yamada M, Fawcett JP, Iulianella A, Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development. J Neurosci. 2022 May 11;42(19):3931-3948 |
1 | J:106946 Stocker AM, Chenn A, Differential expression of alpha-E-catenin and alpha-N-catenin in the developing cerebral cortex. Brain Res. 2006 Feb 16;1073-1074:151-8 |
1* | J:43761 Stoykova A, Gotz M, Gruss P, Price J, Pax6-dependent regulation of adhesive patterning, R-cadherin expression and boundary formation in developing forebrain. Development. 1997 Oct;124(19):3765-77 |
1 | J:160871 Sudarov A, Joyner AL, Cerebellum morphogenesis: the foliation pattern is orchestrated by multi-cellular anchoring centers. Neural Dev. 2007;2:26 |
1 | J:77999 Sugitani Y, Nakai S, Minowa O, Nishi M, Jishage K, Kawano H, Mori K, Ogawa M, Noda T, Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. Genes Dev. 2002 Jul 15;16(14):1760-5 |
1 | J:153504 Torii M, Hashimoto-Torii K, Levitt P, Rakic P, Integration of neuronal clones in the radial cortical columns by EphA and ephrin-A signalling. Nature. 2009 Sep 24;461(7263):524-8 |
1 | J:80512 Tsai RY, McKay RD, A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells. Genes Dev. 2002 Dec 1;16(23):2991-3003 |
1 | J:221658 Vithayathil J, Pucilowska J, Goodnough LH, Atit RP, Landreth GE, Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation. J Neurosci. 2015 Apr 29;35(17):6836-48 |
1 | J:238248 Wang L, Hou S, Han YG, Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex. Nat Neurosci. 2016 Jul;19(7):888-96 |
1 | J:334078 Wang L, Park JY, Liu F, Olesen KM, Hou S, Peng JC, Infield J, Levesque AC, Wang YD, Jin H, Fan Y, Connelly PJ, Pruett-Miller SM, Hu MG, Hinds PW, Han YG, A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2206147119 |
1 | J:235720 Wang PS, Chou FS, Ramachandran S, Xia S, Chen HY, Guo F, Suraneni P, Maher BJ, Li R, Crucial roles of the Arp2/3 complex during mammalian corticogenesis. Development. 2016 Aug 1;143(15):2741-52 |
1 | J:227426 Wiegreffe C, Simon R, Peschkes K, Kling C, Strehle M, Cheng J, Srivatsa S, Liu P, Jenkins NA, Copeland NG, Tarabykin V, Britsch S, Bcl11a (Ctip1) Controls Migration of Cortical Projection Neurons through Regulation of Sema3c. Neuron. 2015 Jul 15;87(2):311-25 |
1 | J:181187 Woo SH, Baba Y, Franco AM, Lumpkin EA, Owens DM, Excitatory glutamate is essential for development and maintenance of the piloneural mechanoreceptor. Development. 2012 Feb;139(4):740-8 |
2 | J:116689 Yamashita N, Uchida Y, Ohshima T, Hirai S, Nakamura F, Taniguchi M, Mikoshiba K, Honnorat J, Kolattukudy P, Thomasset N, Takei K, Takahashi T, Goshima Y, Collapsin response mediator protein 1 mediates reelin signaling in cortical neuronal migration. J Neurosci. 2006 Dec 20;26(51):13357-62 |
1 | J:110232 Yoshimatsu T, Kawaguchi D, Oishi K, Takeda K, Akira S, Masuyama N, Gotoh Y, Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex. Development. 2006 Jul;133(13):2553-63 |
1 | J:363160 Yuizumi N, Harada Y, Kuniya T, Sunabori T, Koike M, Wakabayashi M, Ishihama Y, Suzuki Y, Kawaguchi D, Gotoh Y, Maintenance of neural stem-progenitor cells by the lysosomal biosynthesis regulators TFEB and TFE3 in the embryonic mouse telencephalon. Stem Cells. 2021 Jul;39(7):929-944 |
1 | J:328995 Zhang SF, Dai SK, Du HZ, Wang H, Li XG, Tang Y, Liu CM, The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis. Stem Cell Reports. 2022 Sep 13;17(9):2064-2080 |
1 | J:194642 Zhu B, Xu D, Deng X, Chen Q, Huang Y, Peng H, Li Y, Jia B, Thoreson WB, Ding W, Ding J, Zhao L, Wang Y, Wavrin KL, Duan S, Zheng J, CXCL12 enhances human neural progenitor cell survival through a CXCR7- and CXCR4-mediated endocytotic signaling pathway. Stem Cells. 2012 Nov;30(11):2571-83 |
1 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
1 | J:187723 Zusso M, Methot L, Lo R, Greenhalgh AD, David S, Stifani S, Regulation of postnatal forebrain amoeboid microglial cell proliferation and development by the transcription factor runx1. J Neurosci. 2012 Aug 15;32(33):11285-98 |
Neto1 neuropilin (NRP) and tolloid (TLL)-like 1 (Synonyms: C130005O10Rik) | |
Results | Reference |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Neto2 neuropilin (NRP) and tolloid (TLL)-like 2 (Synonyms: 5530601C23Rik) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Neu1 neuraminidase 1 (Synonyms: Aglp, Apl, Bat-7, Bat7, G9, lysosomal sialidase, Map-2, Neu-1, sialidase 1) | |
Results | Reference |
1 | J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90 |
Neurl2 neuralized E3 ubiquitin protein ligase 2 (Synonyms: Ozz, Ozz-E3) | |
Results | Reference |
1 | J:158726 Campos Y, Qiu X, Zanoteli E, Moshiach S, Vergani N, Bongiovanni A, Harris AJ, d'Azzo A, Ozz-E3 ubiquitin ligase targets sarcomeric embryonic myosin heavy chain during muscle development. PLoS One. 2010;5(3):e9866 |
Neurod1 neurogenic differentiation 1 (Synonyms: BETA2, bHLHa3, Nd1, Neurod) | |
Results | Reference |
1* | J:184001 Ahmed M, Xu J, Xu PX, EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear. Development. 2012 Jun;139(11):1965-77 |
2 | J:156329 Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L, Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. J Biol Chem. 2009 Nov 6;284(45):31236-48 |
1 | J:316182 Blume M, Inoguchi F, Sugiyama T, Owada Y, Osumi N, Aimi Y, Taki K, Katsuyama Y, Dab1 contributes differently to the morphogenesis of the hippocampal subdivisions. Dev Growth Differ. 2017 Oct;59(8):657-673 |
1 | J:315303 Bouche E, Romero-Ortega MI, Henkemeyer M, Catchpole T, Leemhuis J, Frotscher M, May P, Herz J, Bock HH, Reelin induces EphB activation. Cell Res. 2013 Apr;23(4):473-90 |
1 | J:50518 Brown NL, Kanekar S, Vetter ML, Tucker PK, Gemza DL, Glaser T, Math5 encodes a murine basic helix-loop-helix transcription factor expressed during early stages of retinal neurogenesis. Development. 1998 Dec;125(23):4821-33 |
1 | J:200985 Cai EP, Wu X, Schroer SA, Elia AJ, Nostro MC, Zacksenhaus E, Woo M, Retinoblastoma tumor suppressor protein in pancreatic progenitors controls alpha- and beta-cell fate. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14723-8 |
2 | J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5 |
1 | J:264143 Cheung L, Le Tissier P, Goldsmith SG, Treier M, Lovell-Badge R, Rizzoti K, NOTCH activity differentially affects alternative cell fate acquisition and maintenance. Elife. 2018 Mar 26;7:e33318 |
1* | J:104896 Cho JH, Tsai MJ, Preferential posterior cerebellum defect in BETA2/NeuroD1 knockout mice is the result of differential expression of BETA2/NeuroD1 along anterior-posterior axis. Dev Biol. 2006 Feb 1;290(1):125-38 |
1 | J:198451 El-Gohary Y, Tulachan S, Guo P, Welsh C, Wiersch J, Prasadan K, Paredes J, Shiota C, Xiao X, Wada Y, Diaz M, Gittes G, Smad signaling pathways regulate pancreatic endocrine development. Dev Biol. 2013 Jun 15;378(2):83-93 |
1 | J:304355 Garcia-Calero E, Lopez-Gonzalez L, Martinez-de-la-Torre M, Fan CM, Puelles L, Sim1-expressing cells illuminate the origin and course of migration of the nucleus of the lateral olfactory tract in the mouse amygdala. Brain Struct Funct. 2021 Mar;226(2):519-562 |
1 | J:176609 Goldberg LB, Aujla PK, Raetzman LT, Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis. Dev Biol. 2011 Oct 1;358(1):23-32 |
1 | J:219839 Hirota Y, Kubo K, Katayama K, Honda T, Fujino T, Yamamoto TT, Nakajima K, Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex. J Comp Neurol. 2015 Feb 15;523(3):463-78 |
1 | J:196059 Hodge RD, Garcia AJ 3rd, Elsen GE, Nelson BR, Mussar KE, Reiner SL, Ramirez JM, Hevner RF, Tbr2 expression in Cajal-Retzius cells and intermediate neuronal progenitors is required for morphogenesis of the dentate gyrus. J Neurosci. 2013 Feb 27;33(9):4165-80 |
1* | J:170495 Ikeda K, Kageyama R, Suzuki Y, Kawakami K, Six1 is indispensable for production of functional progenitor cells during olfactory epithelial development. Int J Dev Biol. 2010;54(10):1453-64 |
1 | J:64088 Ito T, Udaka N, Yazawa T, Okudela K, Hayashi H, Sudo T, Guillemot F, Kageyama R, Kitamura H, Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development. 2000 Sep;127(18):3913-21 |
1 | J:242970 Jahan I, Pan N, Kersigo J, Calisto LE, Morris KA, Kopecky B, Duncan JS, Beisel KW, Fritzsch B, Expression of Neurog1 instead of Atoh1 can partially rescue organ of Corti cell survival. PLoS One. 2012;7(1):e30853 |
1 | J:334107 Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J, Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice. Hum Mol Genet. 2022 Oct 10;31(20):3504-3520 |
2* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1 | J:257425 Kim DS, Song L, Wang J, Wu H, Gu G, Sugi Y, Li Z, Wang H, GRP94 Is an Essential Regulator of Pancreatic beta-Cell Development, Mass, and Function in Male Mice. Endocrinology. 2018 Feb 1;159(2):1062-1073 |
1 | J:138261 Kokubu H, Ohtsuka T, Kageyama R, Mash1 is required for neuroendocrine cell development in the glandular stomach. Genes Cells. 2008 Jan;13(1):41-51 |
1* | J:136893 Lavoie PL, Budry L, Balsalobre A, Drouin J, Developmental Dependence on NurRE and EboxNeuro for Expression of Pituitary Proopiomelanocortin. Mol Endocrinol. 2008 Jul;22(7):1647-57 |
1* | J:70462 Liu J, Lin C, Gleiberman A, Ohgi KA, Herman T, Huang HP, Tsai MJ, Rosenfeld MG, Tbx19, a tissue-selective regulator of POMC gene expression. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8674-9 |
1 | J:137207 Lynn FC, Sanchez L, Gomis R, German MS, Gasa R, Identification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional network. PLoS One. 2008;3(6):e2430 |
1* | J:114661 Lyu YL, Lin CP, Azarova AM, Cai L, Wang JC, Liu LF, Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Mol Cell Biol. 2006 Nov;26(21):7929-41 |
1 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
1 | J:272073 Nicola Z, Fabel K, Kempermann G, Development of the adult neurogenic niche in the hippocampus of mice. Front Neuroanat. 2015;9:53 |
1 | J:135129 Ohshima T, Hirasawa M, Tabata H, Mutoh T, Adachi T, Suzuki H, Saruta K, Iwasato T, Itohara S, Hashimoto M, Nakajima K, Ogawa M, Kulkarni AB, Mikoshiba K, Cdk5 is required for multipolar-to-bipolar transition during radial neuronal migration and proper dendrite development of pyramidal neurons in the cerebral cortex. Development. 2007 Jun;134(12):2273-82 |
1 | J:331057 Parichha A, Datta D, Suresh V, Chatterjee M, Holtzman MJ, Tole S, Dentate gyrus morphogenesis is regulated by beta-catenin function in hem-derived fimbrial glia. Development. 2022 Nov 1;149(21):dev200953 |
1 | J:81741 Pennesi ME, Cho JH, Yang Z, Wu SH, Zhang J, Wu SM, Tsai MJ, BETA2/NeuroD1 null mice: a new model for transcription factor-dependent photoreceptor degeneration. J Neurosci. 2003 Jan 15;23(2):453-61 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1 | J:129203 Raft S, Koundakjian EJ, Quinones H, Jayasena CS, Goodrich LV, Johnson JE, Segil N, Groves AK, Cross-regulation of Ngn1 and Math1 coordinates the production of neurons and sensory hair cells during inner ear development. Development. 2007 Dec;134(24):4405-15 |
1 | J:127421 Remedios R, Huilgol D, Saha B, Hari P, Bhatnagar L, Kowalczyk T, Hevner RF, Suda Y, Aizawa S, Ohshima T, Stoykova A, Tole S, A stream of cells migrating from the caudal telencephalon reveals a link between the amygdala and neocortex. Nat Neurosci. 2007 Sep;10(9):1141-50 |
1 | J:142359 Seah C, Levy MA, Jiang Y, Mokhtarzada S, Higgs DR, Gibbons RJ, Berube NG, Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53. J Neurosci. 2008 Nov 19;28(47):12570-80 |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
1* | J:203065 Sugiyama T, Osumi N, Katsuyama Y, The germinal matrices in the developing dentate gyrus are composed of neuronal progenitors at distinct differentiation stages. Dev Dyn. 2013 Dec;242(12):1442-53 |
1 | J:216104 Sugiyama T, Osumi N, Katsuyama Y, A novel cell migratory zone in the developing hippocampal formation. J Comp Neurol. 2014 Oct 15;522(15):3520-38 |
2 | J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521 |
1* | J:198233 Wang Y, Lin L, Lai H, Parada LF, Lei L, Transcription factor Sox11 is essential for both embryonic and adult neurogenesis. Dev Dyn. 2013 Jun;242(6):638-53 |
1 | J:174482 Watanabe Y, Inoue K, Okuyama-Yamamoto A, Nakai N, Nakatani J, Nibu K, Sato N, Iiboshi Y, Yusa K, Kondoh G, Takeda J, Terashima T, Takumi T, Fezf1 is required for penetration of the basal lamina by olfactory axons to promote olfactory development. J Comp Neurol. 2009 Aug 10;515(5):565-84 |
1 | J:354849 Wutikeli H, Yu Y, Zhang T, Cao J, Nawy S, Shen Y, Role of Elavl-like RNA-binding protein in retinal development and signal transduction. Biochim Biophys Acta Mol Basis Dis. 2024 Sep 20;1871(1):167518 |
1 | J:325764 Xia Y, Zhang Y, Xu M, Zou X, Gao J, Ji MH, Chen G, Presenilin enhancer 2 is crucial for the transition of apical progenitors into neurons but into not basal progenitors in the developing hippocampus. Development. 2022 May 15;149(10):dev200272 |
1 | J:224155 You L, Yan K, Zhou J, Zhao H, Bertos NR, Park M, Wang E, Yang XJ, The lysine acetyltransferase activator Brpf1 governs dentate gyrus development through neural stem cells and progenitors. PLoS Genet. 2015 Mar;11(3):e1005034 |
1 | J:363160 Yuizumi N, Harada Y, Kuniya T, Sunabori T, Koike M, Wakabayashi M, Ishihama Y, Suzuki Y, Kawaguchi D, Gotoh Y, Maintenance of neural stem-progenitor cells by the lysosomal biosynthesis regulators TFEB and TFE3 in the embryonic mouse telencephalon. Stem Cells. 2021 Jul;39(7):929-944 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Neurod2 neurogenic differentiation 2 (Synonyms: bHLHa1, Ndrf) | |
Results | Reference |
1* | J:359452 Pang Y, Ruan X, Liu W, Hou L, Yin B, Shu P, Peng X, MicroRNA-495 Modulates Neuronal Layer Fate Determination by Targeting Tcf4. Int J Biol Sci. 2024;20(15):6207-6221 |
1 | J:313940 Runge K, Mathieu R, Bugeon S, Lafi S, Beurrier C, Sahu S, Schaller F, Loubat A, Herault L, Gaillard S, Pallesi-Pocachard E, Montheil A, Bosio A, Rosenfeld JA, Hudson E, Lindstrom K, Mercimek-Andrews S, Jeffries L, van Haeringen A, Vanakker O, Van Hecke A, Amrom D, Kury S, Ratner C, Jethva R, Gamble C, Jacq B, Fasano L, Santpere G, Lorente-Galdos B, Sestan N, Gelot A, Giacuzz S, Goebbels S, Represa A, Cardoso C, Cremer H, de Chevigny A, Disruption of NEUROD2 causes a neurodevelopmental syndrome with autistic features via cell-autonomous defects in forebrain glutamatergic neurons. Mol Psychiatry. 2021 Jun 29; |
1 | J:142359 Seah C, Levy MA, Jiang Y, Mokhtarzada S, Higgs DR, Gibbons RJ, Berube NG, Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53. J Neurosci. 2008 Nov 19;28(47):12570-80 |
1 | J:283783 Shu P, Wu C, Ruan X, Liu W, Hou L, Fu H, Wang M, Liu C, Zeng Y, Chen P, Yin B, Yuan J, Qiang B, Peng X, Zhong W, Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell. 2019 Jun 3;49(5):764-785.e4 |
1 | J:324298 Zhou J, Liu G, Zhang X, Wu C, Ma M, Wu J, Hou L, Yin B, Qiang B, Shu P, Peng X, Comparison of the Spatiotemporal Expression Patterns of Three Cre Lines, Emx1IRES-Cre, D6-Cre and hGFAP-Cre, Commonly Used in Neocortical Development Research. Cereb Cortex. 2022 Apr 5;32(8):1668-1681 |
Neurod4 neurogenic differentiation 4 (Synonyms: Atoh3, bHLHa4, Math3, MATH-3) | |
Results | Reference |
1 | J:159104 Cai Z, Feng GS, Zhang X, Temporal requirement of the protein TyrosinePhosphatase Shp2 in establishing the neuronal fatein early retinal development. J Neurosci. 2010 Mar 17;30(11):4110-9 |
1 | J:240480 Kapali J, Kabat BE, Schmidt KL, Stallings CE, Tippy M, Jung DO, Edwards BS, Nantie LB, Raeztman LT, Navratil AM, Ellsworth BS, Foxo1 Is Required for Normal Somatotrope Differentiation. Endocrinology. 2016 Nov;157(11):4351-4363 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:142359 Seah C, Levy MA, Jiang Y, Mokhtarzada S, Higgs DR, Gibbons RJ, Berube NG, Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53. J Neurosci. 2008 Nov 19;28(47):12570-80 |
Neurod6 neurogenic differentiation 6 (Synonyms: Atoh2, bHLHa2, Math-2, Math2, Nex, Nex1m) | |
Results | Reference |
1 | J:316182 Blume M, Inoguchi F, Sugiyama T, Owada Y, Osumi N, Aimi Y, Taki K, Katsuyama Y, Dab1 contributes differently to the morphogenesis of the hippocampal subdivisions. Dev Growth Differ. 2017 Oct;59(8):657-673 |
1* | J:117061 Goebbels S, Bormuth I, Bode U, Hermanson O, Schwab MH, Nave KA, Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice. Genesis. 2006 Dec;44(12):611-21 |
1* | J:25285 Shimizu C, Akazawa C, Nakanishi S, Kageyama R, MATH-2, a mammalian helix-loop-helix factor structurally related to the product of Drosophila proneural gene atonal, is specifically expressed in the nervous system. Eur J Biochem. 1995 Apr 1;229(1):239-48 |
1 | J:216104 Sugiyama T, Osumi N, Katsuyama Y, A novel cell migratory zone in the developing hippocampal formation. J Comp Neurol. 2014 Oct 15;522(15):3520-38 |
Neurog1 neurogenin 1 (Synonyms: bHLHa6, Math4C, Neurod3, neurogenin, neurogenin 1, ngn1) | |
Results | Reference |
1 | J:287136 Aslanpour S, Han S, Schuurmans C, Kurrasch DM, Neurog2 Acts as a Classical Proneural Gene in the Ventromedial Hypothalamus and Is Required for the Early Phase of Neurogenesis. J Neurosci. 2020 Apr 29;40(18):3549-3563 |
1 | J:133461 Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH, Schier AF, Dulac C, Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 2008 Jan 10;57(1):41-55 |
1 | J:147995 Kawauchi S, Kim J, Santos R, Wu HH, Lander AD, Calof AL, Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11. Development. 2009 May;136(9):1453-64 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:298087 Son AI, Mohammad S, Sasaki T, Ishii S, Yamashita S, Hashimoto-Torii K, Torii M, Dual Role of Rbpj in the Maintenance of Neural Progenitor Cells and Neuronal Migration in Cortical Development. Cereb Cortex. 2020 Nov 3;30(12):6444-6457 |
1 | J:275375 Sun S, Zhu XJ, Huang H, Guo W, Tang T, Xie B, Xu X, Zhang Z, Shen Y, Dai ZM, Qiu M, WNT signaling represses astrogliogenesis via Ngn2-dependent direct suppression of astrocyte gene expression. Glia. 2019 Jul;67(7):1333-1343 |
1 | J:188109 Tan SL, Nishi M, Ohtsuka T, Matsui T, Takemoto K, Kamio-Miura A, Aburatani H, Shinkai Y, Kageyama R, Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development. Development. 2012 Oct;139(20):3806-16 |
1* | J:64588 Toresson H, Potter SS, Campbell K, Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for pax6 and gsh2. Development. 2000 Oct;127(20):4361-71 |
1 | J:233479 Vong KI, Leung CK, Behringer RR, Kwan KM, Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum. Mol Brain. 2015;8:25 |
1 | J:229563 Zhao J, Lin Q, Kim KJ, Dardashti FD, Kim J, He F, Sun Y, Ngn1 inhibits astrogliogenesis through induction of miR-9 during neuronal fate specification. Elife. 2015;4:e06885 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Neurog2 neurogenin 2 (Synonyms: Atoh4, bHLHa8, Math4A, ngn2) | |
Results | Reference |
1 | J:353312 Adutwum-Ofosu K, Magnani D, Theil T, Price DJ, Fotaki, The molecular and cellular signatures of the mouse eminentia thalami support its role as a signalling centre in the developing forebrain. Brain Struct Funct. 2016;221(7):3709-27 |
1 | J:287136 Aslanpour S, Han S, Schuurmans C, Kurrasch DM, Neurog2 Acts as a Classical Proneural Gene in the Ventromedial Hypothalamus and Is Required for the Early Phase of Neurogenesis. J Neurosci. 2020 Apr 29;40(18):3549-3563 |
1 | J:50518 Brown NL, Kanekar S, Vetter ML, Tucker PK, Gemza DL, Glaser T, Math5 encodes a murine basic helix-loop-helix transcription factor expressed during early stages of retinal neurogenesis. Development. 1998 Dec;125(23):4821-33 |
2 | J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5 |
1* | J:147117 Cheng TW, Gong Q, Secreted TARSH regulates olfactory mitral cell dendritic complexity. Eur J Neurosci. 2009 Mar;29(6):1083-95 |
1 | J:154611 Chou SJ, Perez-Garcia CG, Kroll TT, O'Leary DD, Lhx2 specifies regional fate in Emx1 lineage of telencephalic progenitors generating cerebral cortex. Nat Neurosci. 2009 Nov;12(11):1381-9 |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
2 | J:134976 Galichet C, Guillemot F, Parras CM, Neurogenin 2 has an essential role in development of the dentate gyrus. Development. 2008 Jun;135(11):2031-41 |
1 | J:310880 Han S, Okawa S, Wilkinson GA, Ghazale H, Adnani L, Dixit R, Tavares L, Faisal I, Brooks MJ, Cortay V, Zinyk D, Sivitilli A, Li S, Malik F, Ilnytskyy Y, Angarica VE, Gao J, Chinchalongporn V, Oproescu AM, Vasan L, Touahri Y, David LA, Raharjo E, Kim JW, Wu W, Rahmani W, Chan JA, Kovalchuk I, Attisano L, Kurrasch D, Dehay C, Swaroop A, Castro DS, Biernaskie J, Del Sol A, Schuurmans C, Proneural genes define ground-state rules to regulate neurogenic patterning and cortical folding. Neuron. 2021 Sep 15;109(18):2847-2863.e11 |
1 | J:176240 Hand R, Polleux F, Neurogenin2 regulates the initial axon guidance of cortical pyramidal neurons projecting medially to the corpus callosum. Neural Dev. 2011;6:30 |
1 | J:160260 Hufnagel RB, Le TT, Riesenberg AL, Brown NL, Neurog2 controls the leading edge of neurogenesis in the mammalian retina. Dev Biol. 2010 Apr 15;340(2):490-503 |
1 | J:122204 Imai F, Hirai S, Akimoto K, Koyama H, Miyata T, Ogawa M, Noguchi S, Sasaoka T, Noda T, Ohno S, Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex. Development. 2006 May;133(9):1735-44 |
1 | J:352077 Kane E, Mak TCS, Latreille M, MicroRNA-7 regulates endocrine progenitor delamination and endocrine cell mass in developing pancreatic islets. iScience. 2024 Jul 19;27(7):110332 |
1 | J:137605 Manuel M, Pratt T, Liu M, Jeffery G, Price DJ, Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance. BMC Dev Biol. 2008;8:59 |
1 | J:214082 Maurer KA, Riesenberg AN, Brown NL, Notch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina. Development. 2014 Aug;141(16):3243-54 |
1* | J:68840 Nakagawa Y, O'Leary DD, Combinatorial expression patterns of LIM-homeodomain and other regulatory genes parcellate developing thalamus. J Neurosci. 2001 Apr 15;21(8):2711-25 |
1 | J:285050 Ochi S, Imaizumi Y, Shimojo H, Miyachi H, Kageyama R, Oscillatory expression of Hes1 regulates cell proliferation and neuronal differentiation in the embryonic brain. Development. 2020 Feb 26;147(4):dev182204 |
1 | J:206963 Orieux G, Picault L, Slembrouck A, Roger JE, Guillonneau X, Sahel JA, Saule S, McPherson JP, Goureau O, Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells. J Neurosci. 2014 Jan 22;34(4):1530-41 |
2 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:142359 Seah C, Levy MA, Jiang Y, Mokhtarzada S, Higgs DR, Gibbons RJ, Berube NG, Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53. J Neurosci. 2008 Nov 19;28(47):12570-80 |
1 | J:84846 Seibt J, Schuurmans C, Gradwhol G, Dehay C, Vanderhaeghen P, Guillemot F, Polleux F, Neurogenin2 specifies the connectivity of thalamic neurons by controlling axon responsiveness to intermediate target cues. Neuron. 2003 Jul 31;39(3):439-52 |
1* | J:65195 Stoykova A, Treichel D, Hallonet M, Gruss P, Pax6 modulates the dorsoventral patterning of the mammalian telencephalon. J Neurosci. 2000 Nov 1;20(21):8042-50 |
1 | J:275375 Sun S, Zhu XJ, Huang H, Guo W, Tang T, Xie B, Xu X, Zhang Z, Shen Y, Dai ZM, Qiu M, WNT signaling represses astrogliogenesis via Ngn2-dependent direct suppression of astrocyte gene expression. Glia. 2019 Jul;67(7):1333-1343 |
1* | J:72724 Toresson H, Campbell K, A role for Gsh1 in the developing striatum and olfactory bulb of Gsh2 mutant mice. Development. 2001 Dec;128(23):4769-80 |
1* | J:64588 Toresson H, Potter SS, Campbell K, Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for pax6 and gsh2. Development. 2000 Oct;127(20):4361-71 |
1 | J:233479 Vong KI, Leung CK, Behringer RR, Kwan KM, Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum. Mol Brain. 2015;8:25 |
1 | J:325764 Xia Y, Zhang Y, Xu M, Zou X, Gao J, Ji MH, Chen G, Presenilin enhancer 2 is crucial for the transition of apical progenitors into neurons but into not basal progenitors in the developing hippocampus. Development. 2022 May 15;149(10):dev200272 |
1 | J:184434 Xiang C, Baubet V, Pal S, Holderbaum L, Tatard V, Jiang P, Davuluri RV, Dahmane N, RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion. Cell Death Differ. 2012 Apr;19(4):692-702 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Neurog3 neurogenin 3 (Synonyms: Atoh5, bHLHa7, Math4B, ngn3) | |
Results | Reference |
1 | J:156329 Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L, Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. J Biol Chem. 2009 Nov 6;284(45):31236-48 |
1 | J:287136 Aslanpour S, Han S, Schuurmans C, Kurrasch DM, Neurog2 Acts as a Classical Proneural Gene in the Ventromedial Hypothalamus and Is Required for the Early Phase of Neurogenesis. J Neurosci. 2020 Apr 29;40(18):3549-3563 |
1 | J:241637 Azzarelli R, Hurley C, Sznurkowska MK, Rulands S, Hardwick L, Gamper I, Ali F, McCracken L, Hindley C, McDuff F, Nestorowa S, Kemp R, Jones K, Gottgens B, Huch M, Evan G, Simons BD, Winton D, Philpott A, Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation. Dev Cell. 2017 May 08;41(3):274-286.e5 |
1 | J:270954 Bankaitis ED, Bechard ME, Gu G, Magnuson MA, Wright CVE, ROCK-nmMyoII, Notch and Neurog3 gene-dosage link epithelial morphogenesis with cell fate in the pancreatic endocrine-progenitor niche. Development. 2018 Sep 21;145(18):dev162115 |
1 | J:226612 Bankaitis ED, Bechard ME, Wright CV, Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche. Genes Dev. 2015 Oct 15;29(20):2203-16 |
2 | J:278226 Bastidas-Ponce A, Tritschler S, Dony L, Scheibner K, Tarquis-Medina M, Salinno C, Schirge S, Burtscher I, Bottcher A, Theis FJ, Lickert H, Bakhti M, Comprehensive single cell mRNA profiling reveals a detailed roadmap for pancreatic endocrinogenesis. Development. 2019 Jun 17;146(12):dev173849 |
1 | J:235658 Bechard ME, Bankaitis ED, Hipkens SB, Ustione A, Piston DW, Yang YP, Magnuson MA, Wright CV, Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells. Genes Dev. 2016 Aug 15;30(16):1852-65 |
1 | J:255164 Broche B, Ben Fradj S, Aguilar E, Sancerni T, Benard M, Makaci F, Berthault C, Scharfmann R, Alves-Guerra MC, Duvillie B, Mitochondrial Protein UCP2 Controls Pancreas Development. Diabetes. 2018 Jan;67(1):78-84 |
1 | J:200985 Cai EP, Wu X, Schroer SA, Elia AJ, Nostro MC, Zacksenhaus E, Woo M, Retinoblastoma tumor suppressor protein in pancreatic progenitors controls alpha- and beta-cell fate. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14723-8 |
1 | J:346123 Darrigrand JF, Salowka A, Torres-Cano A, Tapia-Rojo R, Zhu T, Garcia-Manyes S, Spagnoli FM, Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner. Dev Cell. 2024 Feb 5;59(3):326-338.e5 |
2 | J:220324 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C, Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 1;142(5):871-82 |
1 | J:198451 El-Gohary Y, Tulachan S, Guo P, Welsh C, Wiersch J, Prasadan K, Paredes J, Shiota C, Xiao X, Wada Y, Diaz M, Gittes G, Smad signaling pathways regulate pancreatic endocrine development. Dev Biol. 2013 Jun 15;378(2):83-93 |
1 | J:307319 George NM, Boerner BP, Mir SU, Guinn Z, Sarvetnick NE, Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass. Mol Endocrinol. 2015 Nov;29(11):1594-607 |
2* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1 | J:61566 Huang HP, Liu M, El-Hodiri HM, Chu K, Jamrich M, Tsai MJ, Regulation of the pancreatic islet-specific gene BETA2 (neuroD) by neurogenin 3. Mol Cell Biol. 2000 May;20(9):3292-307 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1 | J:154990 Kang HS, Kim YS, ZeRuth G, Beak JY, Gerrish K, Kilic G, Sosa-Pineda B, Jensen J, Foley J, Jetten AM, Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression. Mol Cell Biol. 2009 Dec;29(24):6366-79 |
1 | J:257425 Kim DS, Song L, Wang J, Wu H, Gu G, Sugi Y, Li Z, Wang H, GRP94 Is an Essential Regulator of Pancreatic beta-Cell Development, Mass, and Function in Male Mice. Endocrinology. 2018 Feb 1;159(2):1062-1073 |
1 | J:138261 Kokubu H, Ohtsuka T, Kageyama R, Mash1 is required for neuroendocrine cell development in the glandular stomach. Genes Cells. 2008 Jan;13(1):41-51 |
1 | J:164411 Lau J, Hebrok M, Hedgehog signaling in pancreas epithelium regulates embryonic organ formation and adult beta-cell function. Diabetes. 2010 May;59(5):1211-21 |
2 | J:80913 Lee J, Wu Y, Qi Y, Xue H, Liu Y, Scheel D, German M, Qiu M, Guillemot F, Rao M, Neurogenin3 participates in gliogenesis in the developing vertebrate spinal cord. Dev Biol. 2003 Jan 1;253(1):84-98 |
1 | J:272578 Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G, Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. Dev Cell. 2019 Jan 7;48(1):49-63.e7 |
1 | J:137207 Lynn FC, Sanchez L, Gomis R, German MS, Gasa R, Identification of the bHLH factor Math6 as a novel component of the embryonic pancreas transcriptional network. PLoS One. 2008;3(6):e2430 |
1 | J:122518 Nelson SB, Schaffer AE, Sander M, The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting beta-cell fate specification in Pdx1+ pancreatic progenitor cells. Development. 2007 Jul;134(13):2491-500 |
2 | J:127412 Nir T, Melton DA, Dor Y, Recovery from diabetes in mice by beta cell regeneration. J Clin Invest. 2007 Sep;117(9):2553-61 |
1* | J:241573 Pui HP, Saga Y, Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling. Mech Dev. 2017 Apr;144(Pt B):125-139 |
1* | J:246476 Raum JC, Soleimanpour SA, Groff DN, Core N, Fasano L, Garratt AN, Dai C, Powers AC, Stoffers DA, Tshz1 Regulates Pancreatic beta-Cell Maturation. Diabetes. 2015 Aug;64(8):2905-14 |
1 | J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356 |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
1 | J:307817 Theis A, Singer RA, Garofalo D, Paul A, Narayana A, Sussel L, Groucho co-repressor proteins regulate beta cell development and proliferation by repressing Foxa1 in the developing mouse pancreas. Development. 2021 Mar 24;148(6):dev192401 |
2 | J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521 |
2 | J:150074 Wang S, Jensen JN, Seymour PA, Hsu W, Dor Y, Sander M, Magnuson MA, Serup P, Gu G, Sustained Neurog3 expression in hormone-expressing islet cells is required for endocrine maturation and function. Proc Natl Acad Sci U S A. 2009 Jun 16;106(24):9715-20 |
1 | J:157959 Wang S, Yan J, Anderson DA, Xu Y, Kanal MC, Cao Z, Wright CV, Gu G, Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas. Dev Biol. 2010 Mar 1;339(1):26-37 |
1 | J:132455 White P, May CL, Lamounier RN, Brestelli JE, Kaestner KH, Defining pancreatic endocrine precursors and their descendants. Diabetes. 2008 Mar;57(3):654-68 |
1* | J:104307 Wilson ME, Yang KY, Kalousova A, Lau J, Kosaka Y, Lynn FC, Wang J, Mrejen C, Episkopou V, Clevers HC, German MS, The HMG Box Transcription Factor Sox4 Contributes to the Development of the Endocrine Pancreas. Diabetes. 2005 Dec;54(12):3402-9 |
1 | J:362739 Wu Y, Qin K, Xu Y, Rajhans S, Vo T, Lopez KM, Liu J, Nipper MH, Deng J, Yin X, Ramjit LR, Ye Z, Luan Y, Arda HE, Wang P, Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation. Elife. 2024 Jul 25;13 |
1 | J:112882 Xu Y, Wang S, Zhang J, Zhao A, Stanger BZ, Gu G, The fringe molecules induce endocrine differentiation in embryonic endoderm by activating cMyt1/cMyt3. Dev Biol. 2006 Sep 15;297(2):340-9 |
Nexmif neurite extension and migration factor (Synonyms: C77370, Xpn) | |
Results | Reference |
1* | J:192375 Ishikawa T, Miyata S, Koyama Y, Yoshikawa K, Hattori T, Kumamoto N, Shingaki K, Katayama T, Tohyama M, Transient expression of Xpn, an XLMR protein related to neurite extension, during brain development and participation in neurite outgrowth. Neuroscience. 2012 Jul 12;214:181-91 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Nf2 neurofibromin 2 (Synonyms: merlin, moesin-ezrin-radixin-like protein, schwannomin) | |
Results | Reference |
1 | J:31660 Claudio JO, Lutchman M, Rouleau GA, Widespread but cell type-specific expression of the mouse neurofibromatosis type 2 gene. Neuroreport. 1995 Oct 2;6(14):1942-6 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
Nfatc1 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 (Synonyms: 2210017P03Rik, NFAT2, NF-ATc, NFATc) | |
Results | Reference |
1* | J:288988 Coudert AE, Redelsperger F, Chabbi-Achengli Y, Vernochet C, Marty C, Decrouy X, Heidmann T, de Vernejoul MC, Dupressoir A, Role of the captured retroviral envelope syncytin-B gene in the fusion of osteoclast and giant cell precursors and in bone resorption, analyzed ex vivo and in vivo in syncytin-B knockout mice. Bone Rep. 2019 Dec;11:100214 |
1 | J:339241 Liu, K., Intercellular genetic tracing of cardiac endothelium in the developing heart. Dev Cell. 2023 Aug 21;58(16):1502-1512 |
1 | J:324116 Morita R, Sanzen N, Sasaki H, Hayashi T, Umeda M, Yoshimura M, Yamamoto T, Shibata T, Abe T, Kiyonari H, Furuta Y, Nikaido I, Fujiwara H, Tracing the origin of hair follicle stem cells. Nature. 2021 Jun;594(7864):547-552 |
1 | J:171374 Osorio KM, Lilja KC, Tumbar T, Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol. 2011 Apr 4;193(1):235-50 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Nfatc2 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 (Synonyms: NFAT1, NFAT1-D, NFATp) | |
Results | Reference |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Nfatc3 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 (Synonyms: D8Ertd281e, NFAT4, NFATx) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Nfatc4 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4 (Synonyms: 3110041H08Rik) | |
Results | Reference |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Nfe2 nuclear factor, erythroid derived 2 (Synonyms: NF-E2, p45, p45nf-e2, p45NFE2) | |
Results | Reference |
1* | J:271614 Gudmundsdottir B, Gudmundsson KO, Klarmann KD, Singh SK, Sun L, Singh S, Du Y, Coppola V, Stockwin L, Nguyen N, Tessarollo L, Thorsteinsson L, Sigurjonsson OE, Gudmundsson S, Rafnar T, Tisdale JF, Keller JR, POGZ Is Required for Silencing Mouse Embryonic beta-like Hemoglobin and Human Fetal Hemoglobin Expression. Cell Rep. 2018 Jun 12;23(11):3236-3248 |
Nfe2l2 nuclear factor, erythroid derived 2, like 2 (Synonyms: Nrf2) | |
Results | Reference |
1 | J:255164 Broche B, Ben Fradj S, Aguilar E, Sancerni T, Benard M, Makaci F, Berthault C, Scharfmann R, Alves-Guerra MC, Duvillie B, Mitochondrial Protein UCP2 Controls Pancreas Development. Diabetes. 2018 Jan;67(1):78-84 |
1* | J:191045 Huebner AJ, Dai D, Morasso M, Schmidt EE, Schafer M, Werner S, Roop DR, Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero. Dev Cell. 2012 Dec 11;23(6):1238-46 |
1 | J:230728 Kumar V, Bouameur JE, Bar J, Rice RH, Hornig-Do HT, Roop DR, Schwarz N, Brodesser S, Thiering S, Leube RE, Wiesner RJ, Vijayaraj P, Brazel CB, Heller S, Binder H, Loffler-Wirth H, Seibel P, Magin TM, A keratin scaffold regulates epidermal barrier formation, mitochondrial lipid composition, and activity. J Cell Biol. 2015 Dec 7;211(5):1057-75 |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
Nfe2l3 nuclear factor, erythroid derived 2, like 3 (Synonyms: Nrf3) | |
Results | Reference |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Nfia nuclear factor I/A (Synonyms: 1110047K16Rik, 9430022M17Rik, NF1-A, NF1A) | |
Results | Reference |
1* | J:39019 Chaudhry AZ, Lyons GE, Gronostajski RM, Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development. Dev Dyn. 1997 Mar;208(3):313-25 |
1* | J:200897 Glasgow SM, Laug D, Brawley VS, Zhang Z, Corder A, Yin Z, Wong ST, Li XN, Foster AE, Ahmed N, Deneen B, The miR-223/Nuclear Factor I-A Axis Regulates Glial Precursor Proliferation and Tumorigenesis in the CNS. J Neurosci. 2013 Aug 14;33(33):13560-13568 |
1 | J:212725 Hong S, Song MR, STAT3 but not STAT1 is required for astrocyte differentiation. PLoS One. 2014;9(1):e86851 |
3* | J:122749 Lu W, Quintero-Rivera F, Fan Y, Alkuraya FS, Donovan DJ, Xi Q, Turbe-Doan A, Li QG, Campbell CG, Shanske AL, Sherr EH, Ahmad A, Peters R, Rilliet B, Parvex P, Bassuk AG, Harris DJ, Ferguson H, Kelly C, Walsh CA, Gronostajski RM, Devriendt K, Higgins A, Ligon AH, Quade BJ, Morton CC, Gusella JF, Maas RL, NFIA haploinsufficiency is associated with a CNS malformation syndrome and urinary tract defects. PLoS Genet. 2007 May 25;3(5):e80 |
1 | J:196051 Moldrich RX, Gobius I, Pollak T, Zhang J, Ren T, Brown L, Mori S, De Juan Romero C, Britanova O, Tarabykin V, Richards LJ, Molecular regulation of the developing commissural plate. J Comp Neurol. 2010 Sep 15;518(18):3645-61 |
1 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:327338 Sartoretti MM, Campetella CA, Lanuza GM, Dbx1 controls the development of astrocytes of the intermediate spinal cord by modulating Notch signaling. Development. 2022 Aug 1;149(15):dev200750 |
1 | J:81202 Shu T, Butz KG, Plachez C, Gronostajski RM, Richards LJ, Abnormal development of forebrain midline glia and commissural projections in Nfia knock-out mice. J Neurosci. 2003 Jan 1;23(1):203-12 |
1 | J:253985 Singh PNP, Yadav US, Azad K, Goswami P, Kinare V, Bandyopadhyay A, NFIA and GATA3 are crucial regulators of embryonic articular cartilage differentiation. Development. 2018 Jan 17;145(2):dev156554 |
1 | J:275375 Sun S, Zhu XJ, Huang H, Guo W, Tang T, Xie B, Xu X, Zhang Z, Shen Y, Dai ZM, Qiu M, WNT signaling represses astrogliogenesis via Ngn2-dependent direct suppression of astrocyte gene expression. Glia. 2019 Jul;67(7):1333-1343 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Nfib nuclear factor I/B (Synonyms: 6720429L07Rik, E030026I10Rik) | |
Results | Reference |
1* | J:39019 Chaudhry AZ, Lyons GE, Gronostajski RM, Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development. Dev Dyn. 1997 Mar;208(3):313-25 |
1* | J:75698 Grunder A, Ebel TT, Mallo M, Schwarzkopf G, Shimizu T, Sippel AE, Schrewe H, Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia. Mech Dev. 2002 Mar;112(1-2):69-77 |
1 | J:173651 Hsu YC, Osinski J, Campbell CE, Litwack ED, Wang D, Liu S, Bachurski CJ, Gronostajski RM, Mesenchymal nuclear factor I B regulates cell proliferation and epithelial differentiation during lung maturation. Dev Biol. 2011 Jun 15;354(2):242-52 |
1 | J:306873 Li L, Jin J, Yang XJ, Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells. iScience. 2019 Oct 25;20:148-167 |
1 | J:96006 Steele-Perkins G, Plachez C, Butz KG, Yang G, Bachurski CJ, Kinsman SL, Litwack ED, Richards LJ, Gronostajski RM, The transcription factor gene Nfib is essential for both lung maturation and brain development. Mol Cell Biol. 2005 Jan;25(2):685-98 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
1 | J:149543 Zhu Y, Matsumoto T, Mikami S, Nagasawa T, Murakami F, SDF1/CXCR4 signalling regulates two distinct processes of precerebellar neuronal migration and its depletion leads to abnormal pontine nuclei formation. Development. 2009 Jun;136(11):1919-28 |
Nfic nuclear factor I/C (Synonyms: 1110019L22Rik, 1500041O16Rik, NF1-C, nuclear factor 1-C2) | |
Results | Reference |
1* | J:39019 Chaudhry AZ, Lyons GE, Gronostajski RM, Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development. Dev Dyn. 1997 Mar;208(3):313-25 |
1 | J:337474 Cobo I, Paliwal S, Bodas C, Felipe I, Melia-Aloma J, Torres A, Martinez-Villarreal J, Malumbres M, Garcia F, Millan I, Del Pozo N, Park JC, MacDonald RJ, Munoz J, Mendez R, Real FX, NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation. Nat Commun. 2023 Jun 23;14(1):3761 |
Nfil3 nuclear factor, interleukin 3, regulated (Synonyms: E4BP4) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Nfix nuclear factor I/X | |
Results | Reference |
1* | J:39019 Chaudhry AZ, Lyons GE, Gronostajski RM, Expression patterns of the four nuclear factor I genes during mouse embryogenesis indicate a potential role in development. Dev Dyn. 1997 Mar;208(3):313-25 |
1 | J:252094 Matuzelski E, Bunt J, Harkins D, Lim JWC, Gronostajski RM, Richards LJ, Harris L, Piper M, Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord. Dev Biol. 2017 Dec 15;432(2):286-297 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:253985 Singh PNP, Yadav US, Azad K, Goswami P, Kinare V, Bandyopadhyay A, NFIA and GATA3 are crucial regulators of embryonic articular cartilage differentiation. Development. 2018 Jan 17;145(2):dev156554 |
1 | J:241609 Taglietti V, Maroli G, Cermenati S, Monteverde S, Ferrante A, Rossi G, Cossu G, Beltrame M, Messina G, Nfix Induces a Switch in Sox6 Transcriptional Activity to Regulate MyHC-I Expression in Fetal Muscle. Cell Rep. 2016 Nov 22;17(9):2354-2366 |
1* | J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903 |
1 | J:149543 Zhu Y, Matsumoto T, Mikami S, Nagasawa T, Murakami F, SDF1/CXCR4 signalling regulates two distinct processes of precerebellar neuronal migration and its depletion leads to abnormal pontine nuclei formation. Development. 2009 Jun;136(11):1919-28 |
Nfkb1 nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105 (Synonyms: NF-kappaB, NF kappaB1, NF-kappaB p50, nuclear factor kappaB p50, p50, p50/p105, p50 subunit of NF kappaB) | |
Results | Reference |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
2 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
Nfkb2 nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100 (Synonyms: NF kappaB2, p52) | |
Results | Reference |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
Nfkbia nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha (Synonyms: I-kappaBalpha, IkappaBalpha, I(Kappa)B(alpha), Nfkbi) | |
Results | Reference |
1* | J:301228 Laugel-Haushalter V, Langer A, Marrie J, Fraulob V, Schuhbaur B, Koch-Phillips M, Dolle P, Bloch-Zupan A, From the transcription of genes involved in ectodermal dysplasias to the understanding of associated dental anomalies. Mol Syndromol. 2012 Oct;3(4):158-68 |
1 | J:255932 Mario Gonzalez-Meljem J, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Neda Mousavy-Gharavy S, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Pedro Martinez-Barbera J, Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. Nat Commun. 2017 Nov 28;8(1):1819 |
1* | J:60742 Rosenfeld ME, Prichard L, Shiojiri N, Fausto N, Prevention of hepatic apoptosis and embryonic lethality in RelA/TNFR-1 double knockout mice. Am J Pathol. 2000 Mar;156(3):997-1007 |
Nfkbib nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta (Synonyms: IKappaBbeta, IkB) | |
Results | Reference |
1* | J:60742 Rosenfeld ME, Prichard L, Shiojiri N, Fausto N, Prevention of hepatic apoptosis and embryonic lethality in RelA/TNFR-1 double knockout mice. Am J Pathol. 2000 Mar;156(3):997-1007 |
Nfya nuclear transcription factor-Y alpha (Synonyms: Cbf-b, Sez10) | |
Results | Reference |
1 | J:316643 Gaspard GJ, MacLean J, Rioux D, Pasumarthi KB, A novel beta-adrenergic response element regulates both basal and agonist-induced expression of cyclin-dependent kinase 1 gene in cardiac fibroblasts. Am J Physiol Cell Physiol. 2014 Mar 15;306(6):C540-50 |
1 | J:345074 Yamanaka T, Kurosawa M, Yoshida A, Shimogori T, Hiyama A, Maity SN, Hattori N, Matsui H, Nukina N, The transcription factor NF-YA is crucial for neural progenitor maintenance during brain development. J Biol Chem. 2024 Jan 8;300(2):105629 |
Nfyb nuclear transcription factor-Y beta (Synonyms: Cbf-A) | |
Results | Reference |
1 | J:316643 Gaspard GJ, MacLean J, Rioux D, Pasumarthi KB, A novel beta-adrenergic response element regulates both basal and agonist-induced expression of cyclin-dependent kinase 1 gene in cardiac fibroblasts. Am J Physiol Cell Physiol. 2014 Mar 15;306(6):C540-50 |
Nfyc nuclear transcription factor-Y gamma | |
Results | Reference |
1 | J:345074 Yamanaka T, Kurosawa M, Yoshida A, Shimogori T, Hiyama A, Maity SN, Hattori N, Matsui H, Nukina N, The transcription factor NF-YA is crucial for neural progenitor maintenance during brain development. J Biol Chem. 2024 Jan 8;300(2):105629 |
Ngb neuroglobin | |
Results | Reference |
1 | J:327067 Shang L, Mao D, Li Z, Gao X, Deng J, Neuroglobin Is Involved in the Hypoxic Stress Response in the Brain. Biomed Res Int. 2022;2022:8263373 |
Ngef neuronal guanine nucleotide exchange factor (Synonyms: ephexin, Tims2) | |
Results | Reference |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Ngf nerve growth factor | |
Results | Reference |
1 | J:65040 Botchkareva NV, Botchkarev VA, Albers KM, Metz M, Paus R, Distinct roles for nerve growth factor and brain-derived neurotrophic factor in controlling the rate of hair follicle morphogenesis. J Invest Dermatol. 2000 Feb;114(2):314-20 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34 |
1 | J:237233 Tomlinson RE, Li Z, Zhang Q, Goh BC, Li Z, Thorek DL, Rajbhandari L, Brushart TM, Minichiello L, Zhou F, Venkatesan A, Clemens TL, NGF-TrkA Signaling by Sensory Nerves Coordinates the Vascularization and Ossification of Developing Endochondral Bone. Cell Rep. 2016 Sep 06;16(10):2723-35 |
Ngfr nerve growth factor receptor (TNFR superfamily, member 16) (Synonyms: LNGFR, p75, p75 neurotrophin receptor, p75NGFR, p75NTR, Tnfrsf16) | |
Results | Reference |
1 | J:82462 Agerman K, Hjerling-Leffler J, Blanchard MP, Scarfone E, Canlon B, Nosrat C, Ernfors P, BDNF gene replacement reveals multiple mechanisms for establishing neurotrophin specificity during sensory nervous system development. Development. 2003 Apr;130(8):1479-91 |
1 | J:241827 Aoki M, Takeuchi H, Nakashima A, Nishizumi H, Sakano H, Possible roles of Robo1+ ensheathing cells in guiding dorsal-zone olfactory sensory neurons in mouse. Dev Neurobiol. 2013 Nov;73(11):828-40 |
1 | J:109287 Balmer CW, LaMantia AS, Loss of Gli3 and Shh function disrupts olfactory axon trajectories. J Comp Neurol. 2004 May 3;472(3):292-307 |
1* | J:199435 Barraud P, St John JA, Stolt CC, Wegner M, Baker CV, Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Biol Open. 2013 Jul 15;2(7):750-9 |
1 | J:276488 Bilodeau M, Shojaie S, Ackerley C, Post M, Rossant J, Identification of a proximal progenitor population from murine fetal lungs with clonogenic and multilineage differentiation potential. Stem Cell Reports. 2014 Oct 14;3(4):634-49 |
1 | J:58865 Botchkareva NV, Botchkarev VA, Chen LH, Lindner G, Paus R, A role for p75 neurotrophin receptor in the control of hair follicle morphogenesis. Dev Biol. 1999 Dec 1;216(1):135-53 |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1 | J:338830 Connor B, Moya-Alvarado G, Yamashita N, Kuruvilla R, Transcytosis-mediated anterograde transport of TrkA receptors is necessary for sympathetic neuron development and function. Proc Natl Acad Sci U S A. 2023 Feb 7;120(6):e2205426120 |
1 | J:80220 Corradi A, Croci L, Broccoli V, Zecchini S, Previtali S, Wurst W, Amadio S, Maggi R, Quattrini A, Consalez GG, Hypogonadotropic hypogonadism and peripheral neuropathy in Ebf2-null mice. Development. 2003 Jan;130(2):401-10 |
1 | J:166772 DeRouen MC, Zhen H, Tan SH, Williams S, Marinkovich MP, Oro AE, Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation. BMC Dev Biol. 2010;10:112 |
1* | J:296604 Durbeej M, Soderstrom S, Ebendal T, Birchmeier C, Ekblom P, Differential expression of neurotrophin receptors during renal development. Development. 1993 Dec;119(4):977-89 |
2 | J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109 |
1 | J:26749 Ernfors P, Van De Water T, Loring J, Jaenisch R, Complementary roles of BDNF and NT-3 in vestibular and auditory development. Neuron. 1995 Jun;14(6):1153-64 |
1 | J:223161 Gahring LC, Myers E, Palumbos S, Rogers SW, Nicotinic receptor Alpha7 expression during mouse adrenal gland development. PLoS One. 2014;9(8):e103861 |
1 | J:126322 Gao X, Daugherty RL, Tourtellotte WG, Regulation of low affinity neurotrophin receptor (p75(NTR)) by early growth response (Egr) transcriptional regulators. Mol Cell Neurosci. 2007 Dec;36(4):501-14 |
1 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1 | J:160258 Holley M, Rhodes C, Kneebone A, Herde MK, Fleming M, Steel KP, Emx2 and early hair cell development in the mouse inner ear. Dev Biol. 2010 Apr 15;340(2):547-56 |
1 | J:70744 Huang EJ, Liu W, Fritzsch B, Bianchi LM, Reichardt LF, Xiang M, Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons. Development. 2001 Jul;128(13):2421-32 |
1 | J:315409 Huyghe A, Van den Ackerveken P, Sacheli R, Prevot PP, Thelen N, Renauld J, Thiry M, Delacroix L, Nguyen L, Malgrange B, MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5. Cell Rep. 2015 Oct 6;13(1):31-42 |
1 | J:197212 Kim HJ, Woo HM, Ryu J, Bok J, Kim JW, Choi SB, Park MH, Park HY, Koo SK, Conditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development. PLoS One. 2013;8(2):e55609 |
1 | J:197034 Lopez-Sanchez N, Frade JM, Genetic evidence for p75NTR-dependent tetraploidy in cortical projection neurons from adult mice. J Neurosci. 2013 Apr 24;33(17):7488-500 |
1 | J:215095 Mao Y, Reiprich S, Wegner M, Fritzsch B, Targeted deletion of Sox10 by Wnt1-cre defects neuronal migration and projection in the mouse inner ear. PLoS One. 2014;9(4):e94580 |
1 | J:341276 Matrongolo MJ, Ho-Nguyen KT, Jain M, Ang PS, Reddy A, Schaper S, Tischfield MA, Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice. Development. 2023 Sep 15;150(18):dev201381 |
1 | J:37118 McEvilly RJ, Erkman L, Luo L, Sawchenko PE, Ryan AF, Rosenfeld MG, Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature. 1996 Dec 12;384(6609):574-7 |
1 | J:76254 McQuillen PS, DeFreitas MF, Zada G, Shatz CJ, A novel role for p75NTR in subplate growth cone complexity and visual thalamocortical innervation. J Neurosci. 2002 May 1;22(9):3580-93 |
1 | J:284129 Meier S, Alfonsi F, Kurniawan ND, Milne MR, Kasherman MA, Delogu A, Piper M, Coulson EJ, The p75 neurotrophin receptor is required for the survival of neuronal progenitors and normal formation of the basal forebrain, striatum, thalamus and neocortex. Development. 2019 Sep 18;146(18):dev181933 |
2 | J:182762 Mundell NA, Plank JL, LeGrone AW, Frist AY, Zhu L, Shin MK, Southard-Smith EM, Labosky PA, Enteric nervous system specific deletion of Foxd3 disrupts glial cell differentiation and activates compensatory enteric progenitors. Dev Biol. 2012 Mar 15;363(2):373-87 |
1 | J:78879 Pirvola U, Ylikoski J, Trokovic R, Hebert JM, McConnell SK, Partanen J, FGFR1 is required for the development of the auditory sensory epithelium. Neuron. 2002 Aug 15;35(4):671-80 |
1 | J:313294 Raucci F, Tiong JD, Wray S, P75 nerve growth factor receptors modulate development of GnRH neurons and olfactory ensheating cells. Front Neurosci. 2013;7:262 |
1 | J:137872 Suzuki K, Tanaka M, Watanabe N, Saito S, Nonaka H, Miyajima A, p75 Neurotrophin receptor is a marker for precursors of stellate cells and portal fibroblasts in mouse fetal liver. Gastroenterology. 2008 Jul;135(1):270-281.e3 |
1 | J:86789 Szeder V, Grim M, Kucera J, Sieber-Blum M, Neurotrophin-3 signaling in mammalian Merkel cell development. Dev Dyn. 2003 Dec;228(4):623-9 |
1 | J:361594 Traynor S, Bhattacharya S, Batmanov K, Cheng L, Weller A, Moore N, Flesher C, Merrick D, Developmental regulation of dermal adipose tissue by BCL11b. Genes Dev. 2024 Sep 19;38(15-16):772-783 |
1 | J:278634 Wilkerson BA, Chitsazan AD, VandenBosch LS, Wilken MS, Reh TA, Bermingham-McDonogh O, Open chromatin dynamics in prosensory cells of the embryonic mouse cochlea. Sci Rep. 2019 Jun 21;9(1):9060 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
1 | J:81003 Young HM, Bergner AJ, Muller T, Acquisition of neuronal and glial markers by neural crest-derived cells in the mouse intestine. J Comp Neurol. 2003 Jan 27;456(1):1-11 |
2 | J:329949 Yuan H, Xie B, Yu X, Lin C, Li M, Zhang Y, Zou X, Lu M, Zhao M, Wen X, A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development. Front Physiol. 2022;13:981311 |
1* | J:59182 Zhou C, Qiu Y, Pereira FA, Crair MC, Tsai SY, Tsai MJ, The nuclear orphan receptor COUP-TFI is required for differentiation of subplate neurons and guidance of thalamocortical axons. Neuron. 1999 Dec;24(4):847-59 |
Nherf1 NHERF family PDZ scaffold protein 1 (Synonyms: EBP-50, NHE-RF, NHERF1, Slc9a3r1, sodium-hydrogen exchanger regulatory factor) | |
Results | Reference |
2 | J:263981 Benhamouche-Trouillet S, O'Loughlin E, Liu CH, Polacheck W, Fitamant J, McKee M, El-Bardeesy N, Chen CS, McClatchey AI, Proliferation-independent role of NF2 (merlin) in limiting biliary morphogenesis. Development. 2018 Apr 30;145(9):dev162123 |
1 | J:346405 Vitureira N, Andres R, Perez-Martinez E, Martinez A, Bribian A, Blasi J, Chelliah S, Lopez-Domenech G, De Castro F, Burgaya F, McNagny K, Soriano E, Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation. PLoS One. 2010 Aug 10;5(8):e12003 |
Nherf2 NHERF family PDZ scaffold protein 2 (Synonyms: 0610011L07Rik, 1200011K07Rik, 2010007A20Rik, E3karp, Nherf2, Octs2, Sip-1, Sip1, Slc9a3r2, Sryip1, Tka-1) | |
Results | Reference |
1 | J:346405 Vitureira N, Andres R, Perez-Martinez E, Martinez A, Bribian A, Blasi J, Chelliah S, Lopez-Domenech G, De Castro F, Burgaya F, McNagny K, Soriano E, Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation. PLoS One. 2010 Aug 10;5(8):e12003 |
Nhlh1 nescient helix loop helix 1 (Synonyms: bHLHa35, Hen1, Nscl, Nscl, Tal2) | |
Results | Reference |
1 | J:78031 Cogliati T, Good DJ, Haigney M, Delgado-Romero P, Eckhaus MA, Koch WJ, Kirsch IR, Predisposition to arrhythmia and autonomic dysfunction in Nhlh1-deficient mice. Mol Cell Biol. 2002 Jul;22(14):4977-83 |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
1 | J:220948 Jahan I, Pan N, Kersigo J, Fritzsch B, Neurod1 suppresses hair cell differentiation in ear ganglia and regulates hair cell subtype development in the cochlea. PLoS One. 2010;5(7):e11661 |
1* | J:112915 Kruger M, Schmid T, Kruger S, Bober E, Braun T, Functional redundancy of NSCL-1 and NeuroD during development of the petrosal and vestibulocochlear ganglia. Eur J Neurosci. 2006 Sep;24(6):1581-90 |
1 | J:125013 Schmid T, Kruger M, Braun T, NSCL-1 and -2 control the formation of precerebellar nuclei by orchestrating the migration of neuronal precursor cells. J Neurochem. 2007 Sep;102(6):2061-72 |
Nhlh2 nescient helix loop helix 2 (Synonyms: 6230401I09Rik, bHLHa34, Hen2, Nscl-2, NSCL2) | |
Results | Reference |
1 | J:78031 Cogliati T, Good DJ, Haigney M, Delgado-Romero P, Eckhaus MA, Koch WJ, Kirsch IR, Predisposition to arrhythmia and autonomic dysfunction in Nhlh1-deficient mice. Mol Cell Biol. 2002 Jul;22(14):4977-83 |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
1 | J:93303 Kruger M, Ruschke K, Braun T, NSCL-1 and NSCL-2 synergistically determine the fate of GnRH-1 neurons and control necdin gene expression. EMBO J. 2004 Nov 27;23(21):4353-64 |
1* | J:112915 Kruger M, Schmid T, Kruger S, Bober E, Braun T, Functional redundancy of NSCL-1 and NeuroD during development of the petrosal and vestibulocochlear ganglia. Eur J Neurosci. 2006 Sep;24(6):1581-90 |
1 | J:125013 Schmid T, Kruger M, Braun T, NSCL-1 and -2 control the formation of precerebellar nuclei by orchestrating the migration of neuronal precursor cells. J Neurochem. 2007 Sep;102(6):2061-72 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
Nhs NHS actin remodeling regulator (Synonyms: LOC195727, LOC245686, Nance-Horan syndrome (human)) | |
Results | Reference |
1* | J:151303 Burdon KP, McKay JD, Sale MM, Russell-Eggitt IM, Mackey DA, Wirth MG, Elder JE, Nicoll A, Clarke MP, FitzGerald LM, Stankovich JM, Shaw MA, Sharma S, Gajovic S, Gruss P, Ross S, Thomas P, Voss AK, Thomas T, Gecz J, Craig JE, Mutations in a novel gene, NHS, cause the pleiotropic effects of Nance-Horan syndrome, including severe congenital cataract, dental anomalies, and mental retardation. Am J Hum Genet. 2003 Nov;73(5):1120-30 |
Nid1 nidogen 1 (Synonyms: entactin, entactin 1, entactin-1, nidogen-1) | |
Results | Reference |
1 | J:119851 DiPersio CM, van der Neut R, Georges-Labouesse E, Kreidberg JA, Sonnenberg A, Hynes RO, alpha3beta1 and alpha6beta4 integrin receptors for laminin-5 are not essential for epidermal morphogenesis and homeostasis during skin development. J Cell Sci. 2000 Sep;113(Pt 17):3051-62 |
1* | J:30369 Enders GC, Kahsai TZ, Lian G, Funabiki K, Killen PD, Hudson BG, Developmental changes in seminiferous tubule extracellular matrix components of the mouse testis: alpha 3(IV) collagen chain expressed at the initiation of spermatogenesis. Biol Reprod. 1995 Dec;53(6):1489-99 |
1 | J:196018 Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W, Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell Rep. 2012 Jul 26;2(1):52-61 |
1 | J:195888 Gustafsson E, Almonte-Becerril M, Bloch W, Costell M, Perlecan maintains microvessel integrity in vivo and modulates their formation in vitro. PLoS One. 2013;8(1):e53715 |
1 | J:134970 Inoue T, Ogawa M, Mikoshiba K, Aruga J, Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly. J Neurosci. 2008 Apr 30;28(18):4712-25 |
1 | J:329963 Janardhan HP, Dresser K, Hutchinson L, Trivedi CM, Pathological MAPK activation-mediated lymphatic basement membrane disruption causes lymphangiectasia that is treatable with ravoxertinib. JCI Insight. 2022 Sep 8;7(17):e153033 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1* | J:59925 Miner JH, Li C, Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane. Dev Biol. 2000 Jan 15;217(2):278-89 |
1 | J:77264 Nguyen NM, Miner JH, Pierce RA, Senior RM, Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung. Dev Biol. 2002 Jun 15;246(2):231-44 |
1* | J:79202 Salmivirta K, Talts JF, Olsson M, Sasaki T, Timpl R, Ekblom P, Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens. Exp Cell Res. 2002 Oct 1;279(2):188-201 |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Nid2 nidogen 2 (Synonyms: entactin 2, entactin-2) | |
Results | Reference |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1* | J:79202 Salmivirta K, Talts JF, Olsson M, Sasaki T, Timpl R, Ekblom P, Binding of mouse nidogen-2 to basement membrane components and cells and its expression in embryonic and adult tissues suggest complementary functions of the two nidogens. Exp Cell Res. 2002 Oct 1;279(2):188-201 |
Nif3l1 Ngg1 interacting factor 3-like 1 (S. pombe) (Synonyms: 1110030G24Rik) | |
Results | Reference |
1* | J:66699 Tascou S, Uedelhoven J, Dixkens C, Nayernia K, Engel W, Burfeind P, Isolation and characterization of a novel human gene, NIF3L1, and its mouse ortholog, Nif3l1, highly conserved from bacteria to mammals. Cytogenet Cell Genet. 2000;90(3-4):330-6 |
Nin ninein (Synonyms: 3110068G20Rik, mKIAA1565) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:219928 Srivatsa S, Parthasarathy S, Molnar Z, Tarabykin V, Sip1 Downstream Effector ninein Controls Neocortical Axonal Growth, Ipsilateral Branching, and Microtubule Growth and Stability. Neuron. 2015 Mar 4;85(5):998-1012 |
Ninj1 ninjurin 1 | |
Results | Reference |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Nipa1 non imprinted in Prader-Willi/Angelman syndrome 1 homolog (human) (Synonyms: 1110027G09Rik, A830014A18Rik, Spg6) | |
Results | Reference |
1* | J:161575 van der Zwaag B, Staal WG, Hochstenbach R, Poot M, Spierenburg HA, de Jonge MV, Verbeek NE, van 't Slot R, van Es MA, Staal FJ, Freitag CM, Buizer-Voskamp JE, Nelen MR, van den Berg LH, van Amstel HK, van Engeland H, Burbach JP, A co-segregating microduplication of chromosome 15q11.2 pinpoints two risk genes for autism spectrum disorder. Am J Med Genet B Neuropsychiatr Genet. 2010 Jun 5;153B(4):960-6 |
Nipal3 NIPA-like domain containing 3 (Synonyms: 9130020G22Rik, Npal3) | |
Results | Reference |
1* | J:152829 Grzmil P, Konietzko J, Boehm D, Hoelter SM, Aguilar A, Javaheri A, Kalaydjiev S, Adler T, Bolle I, Adham I, Dixkens C, Wolf S, Fuchs H, Gailus-Durne V, Wurst W, Ollert M, Busch D, Schulz H, de Angelis MH, Burfeind P, Targeted disruption of the mouse Npal3 gene leads to deficits in behavior, increased IgE levels, and impaired lung function. Cytogenet Genome Res. 2009;125(3):186-200 |
Nisch nischarin (Synonyms: 1200007D05Rik, 3202002H23Rik, edsn) | |
Results | Reference |
1 | J:258027 Gstrein T, Edwards A, Pristoupilova A, Leca I, Breuss M, Pilat-Carotta S, Hansen AH, Tripathy R, Traunbauer AK, Hochstoeger T, Rosoklija G, Repic M, Landler L, Stranecky V, Durnberger G, Keane TM, Zuber J, Adams DJ, Flint J, Honzik T, Gut M, Beltran S, Mechtler K, Sherr E, Kmoch S, Gut I, Keays DA, Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans. Nat Neurosci. 2018 Feb;21(2):207-217 |
Nkd1 naked cuticle 1 (Synonyms: 2810434J10Rik, 9030215G15Rik) | |
Results | Reference |
1* | J:258542 Hupe M, Li MX, Kneitz S, Davydova D, Yokota C, Kele-Olovsson J, Hot B, Stenman JM, Gessler M, Gene expression profiles of brain endothelial cells during embryonic development at bulk and single-cell levels. Sci Signal. 2017 Jul 11;10(487) |
1 | J:328944 Olbertova K, Hrckulak D, Kriz V, Jesionek W, Kubovciak J, Esner M, Korinek V, Buchtova M, Role of LGR5-positive mesenchymal cells in craniofacial development. Front Cell Dev Biol. 2022;10:810527 |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
1* | J:105879 Zhang TJ, Hoffman BG, Ruiz de Algara T, Helgason CD, SAGE reveals expression of Wnt signalling pathway members during mouse prostate development. Gene Expr Patterns. 2006 Mar;6(3):310-24 |
Nkd2 naked cuticle 2 (Synonyms: 2210403L10Rik) | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Nkx1-1 NK1 homeobox 1 (Synonyms: Nkx-1.1, Sax2) | |
Results | Reference |
1 | J:86868 Simon R, Lufkin T, Postnatal lethality in mice lacking the Sax2 homeobox gene homologous to Drosophila S59/slouch: evidence for positive and negative autoregulation. Mol Cell Biol. 2003 Dec;23(24):9046-60 |
Nkx1-2 NK1 homeobox 2 (Synonyms: Nkx-1.1, Nkx-1.2, Sax1) | |
Results | Reference |
1 | J:197180 Buniello A, Hardisty-Hughes RE, Pass JC, Bober E, Smith RJ, Steel KP, Headbobber: a combined morphogenetic and cochleosaccular mouse model to study 10qter deletions in human deafness. PLoS One. 2013;8(2):e56274 |
Nkx2-1 NK2 homeobox 1 (Synonyms: T/EBP, thyroid-specific enhancer-binding protein, thyroid transcription factor-1, tinman, Titf1, Ttf-1) | |
Results | Reference |
1 | J:315117 Baudoin JP, Viou L, Launay PS, Luccardini C, Espeso Gil S, Kiyasova V, Irinopoulou T, Alvarez C, Rio JP, Boudier T, Lechaire JP, Kessaris N, Spassky N, Metin C, Tangentially migrating neurons assemble a primary cilium that promotes their reorientation to the cortical plate. Neuron. 2012 Dec 20;76(6):1108-22 |
1 | J:173973 Benlhabib H, Mendelson CR, Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia. Mol Cell Biol. 2011 May;31(10):1949-58 |
1 | J:104973 Besnard V, Wert SE, Kaestner KH, Whitsett JA, Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1. Am J Physiol Lung Cell Mol Physiol. 2005 Nov;289(5):L750-9 |
1* | J:193583 Cai Y, Zhang Q, Wang C, Zhang Y, Ma T, Zhou X, Tian M, Rubenstein JL, Yang Z, Nuclear receptor COUP-TFII-expressing neocortical interneurons are derived from the medial and lateral/caudal ganglionic eminence and define specific subsets of mature interneurons. J Comp Neurol. 2013 Feb 1;521(2):479-97 |
1* | J:171072 Carre A, Rachdi L, Tron E, Richard B, Castanet M, Schlumberger M, Bidart JM, Szinnai G, Polak M, Hes1 is required for appropriate morphogenesis and differentiation during mouse thyroid gland development. PLoS One. 2011;6(2):e16752 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:339854 Chen SY, Liu FC, The Fgf9-Nolz1-Wnt2 axis regulates morphogenesis of the lung. Development. 2023 Aug 15;150(16):dev201827 |
1 | J:213234 Cho HH, Cargnin F, Kim Y, Lee B, Kwon RJ, Nam H, Shen R, Barnes AP, Lee JW, Lee S, Lee SK, Isl1 directly controls a cholinergic neuronal identity in the developing forebrain and spinal cord by forming cell type-specific complexes. PLoS Genet. 2014 Apr;10(4):e1004280 |
1 | J:129796 Conkright JJ, Na CL, Weaver TE, Overexpression of surfactant protein-C mature peptide causes neonatal lethality in transgenic mice. Am J Respir Cell Mol Biol. 2002 Jan;26(1):85-90 |
1 | J:197849 Deck M, Lokmane L, Chauvet S, Mailhes C, Keita M, Niquille M, Yoshida M, Yoshida Y, Lebrand C, Mann F, Grove EA, Garel S, Pathfinding of corticothalamic axons relies on a rendezvous with thalamic projections. Neuron. 2013 Feb 6;77(3):472-84 |
1 | J:316977 Endale M, Ahlfeld S, Bao E, Chen X, Green J, Bess Z, Weirauch MT, Xu Y, Perl AK, Temporal, spatial, and phenotypical changes of PDGFRalpha expressing fibroblasts during late lung development. Dev Biol. 2017 May 15;425(2):161-175 |
1 | J:220467 Galvis LA, Holik AZ, Short KM, Pasquet J, Lun AT, Blewitt ME, Smyth IM, Ritchie ME, Asselin-Labat ML, Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung. Development. 2015 Apr 15;142(8):1458-69 |
2 | J:163224 Garcia-Lopez M, Abellan A, Legaz I, Rubenstein JL, Puelles L, Medina L, Histogenetic compartments of the mouse centromedial and extended amygdala based on gene expression patterns during development. J Comp Neurol. 2008 Jan 1;506(1):46-74 |
1* | J:260471 Gerhardt B, Leesman L, Burra K, Snowball J, Rosenzweig R, Guzman N, Ambalavanan M, Sinner D, Notum attenuates Wnt/beta-catenin signaling to promote tracheal cartilage patterning. Dev Biol. 2018 Apr 1;436(1):14-27 |
1 | J:270164 Guo M, Du Y, Gokey JJ, Ray S, Bell SM, Adam M, Sudha P, Perl AK, Deshmukh H, Potter SS, Whitsett JA, Xu Y, Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth. Nat Commun. 2019 Jan 3;10(1):37 |
2 | J:354192 He H, Bell SM, Davis AK, Zhao S, Sridharan A, Na CL, Guo M, Xu Y, Snowball J, Swarr DT, Zacharias WJ, Whitsett JA, PRDM3/16 regulate chromatin accessibility required for NKX2-1 mediated alveolar epithelial differentiation and function. Nat Commun. 2024 Sep 16;15(1):8112 |
1* | J:212084 Herriges MJ, Swarr DT, Morley MP, Rathi KS, Peng T, Stewart KM, Morrisey EE, Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development. Genes Dev. 2014 Jun 15;28(12):1363-79 |
1* | J:243650 Herriges MJ, Tischfield DJ, Cui Z, Morley MP, Han Y, Babu A, Li S, Lu M, Cendan I, Garcia BA, Anderson SA, Morrisey EE, The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis. Genes Dev. 2017 May 01;31(9):889-903 |
2 | J:200722 Hick AC, Delmarcelle AS, Bouquet M, Klotz S, Copetti T, Forez C, Van Der Smissen P, Sonveaux P, Collet JF, Feron O, Courtoy PJ, Pierreux CE, Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiation. Dev Biol. 2013 Sep 1;381(1):227-40 |
1 | J:173651 Hsu YC, Osinski J, Campbell CE, Litwack ED, Wang D, Liu S, Bachurski CJ, Gronostajski RM, Mesenchymal nuclear factor I B regulates cell proliferation and epithelial differentiation during lung maturation. Dev Biol. 2011 Jun 15;354(2):242-52 |
1 | J:327969 Khattar D, Fernandes S, Snowball J, Guo M, Gillen MC, Jain SS, Sinner D, Zacharias W, Swarr DT, PI3K signaling specifies proximal-distal fate by driving a developmental gene regulatory network in SOX9+ mouse lung progenitors. Elife. 2022 Aug 17;11:e67954 |
1 | J:336092 Knowles SJ, Stafford AM, Zaman T, Angara K, Williams MR, Newbern JM, Vogt D, Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs. Development. 2023 May 15;150(10):dev201371 |
1 | J:111027 Kusakabe T, Kawaguchi A, Hoshi N, Kawaguchi R, Hoshi S, Kimura S, Thyroid-specific enhancer-binding protein/NKX2.1 is required for the maintenance of ordered architecture and function of the differentiated thyroid. Mol Endocrinol. 2006 Aug;20(8):1796-809 |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
1 | J:315454 Loscertales M, Nicolaou F, Jeanne M, Longoni M, Gould DB, Sun Y, Maalouf FI, Nagy N, Donahoe PK, Type IV collagen drives alveolar epithelial-endothelial association and the morphogenetic movements of septation. BMC Biol. 2016 Jul 13;14:59 |
1 | J:219800 Lungova V, Verheyden JM, Herriges J, Sun X, Thibeault SL, Ontogeny of the mouse vocal fold epithelium. Dev Biol. 2015 Mar 15;399(2):263-82 |
1 | J:254523 Magno L, Barry C, Schmidt-Hieber C, Theodotou P, Hausser M, Kessaris N, NKX2-1 Is Required in the Embryonic Septum for Cholinergic System Development, Learning, and Memory. Cell Rep. 2017 Aug 15;20(7):1572-1584 |
1 | J:184343 Magno L, Kretz O, Bert B, Ersozlu S, Vogt J, Fink H, Kimura S, Vogt A, Monyer H, Nitsch R, Naumann T, The integrity of cholinergic basal forebrain neurons depends on expression of Nkx2-1. Eur J Neurosci. 2011 Dec;34(11):1767-82 |
1 | J:227683 Marin O, Anderson SA, Rubenstein JL, Origin and molecular specification of striatal interneurons. J Neurosci. 2000 Aug 15;20(16):6063-76 |
1 | J:275078 Minocha S, Valloton D, Arsenijevic Y, Cardinaux JR, Guidi R, Hornung JP, Lebrand C, Nkx2.1 regulates the generation of telencephalic astrocytes during embryonic development. Sci Rep. 2017 Mar 7;7:43093 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
1 | J:264719 Moghieb A, Clair G, Mitchell HD, Kitzmiller J, Zink EM, Kim YM, Petyuk V, Shukla A, Moore RJ, Metz TO, Carson J, McDermott JE, Corley RA, Whitsett JA, Ansong C, Time-resolved proteome profiling of normal lung development. Am J Physiol Lung Cell Mol Physiol. 2018 Jul 1;315(1):L11-L24 |
1 | J:77264 Nguyen NM, Miner JH, Pierce RA, Senior RM, Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung. Dev Biol. 2002 Jun 15;246(2):231-44 |
1* | J:113028 Niimi T, Kurotani R, Kimura S, Kitagawa Y, Identification and expression of alternative splice variants of the mouse Ppp1r3b gene in lung epithelial cells. Biochem Biophys Res Commun. 2006 Oct 20;349(2):588-96 |
1 | J:135340 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia. BMC Dev Biol. 2008;8:2 |
1* | J:137010 Petrou P, Pavlakis E, Dalezios Y, Galanopoulos VK, Chalepakis G, Basement membrane distortions impair lung lobation and capillary organization in the mouse model for fraser syndrome. J Biol Chem. 2005 Mar 18;280(11):10350-6 |
1* | J:85949 Shikama N, Lutz W, Kretzschmar R, Sauter N, Roth JF, Marino S, Wittwer J, Scheidweiler A, Eckner R, Essential function of p300 acetyltransferase activity in heart, lung and small intestine formation. EMBO J. 2003 Oct 1;22(19):5175-85 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:99391 Shu W, Guttentag S, Wang Z, Andl T, Ballard P, Lu MM, Piccolo S, Birchmeier W, Whitsett JA, Millar SE, Morrisey EE, Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung. Dev Biol. 2005 Jul 1;283(1):226-39 |
2 | J:121421 Shu W, Lu MM, Zhang Y, Tucker PW, Zhou D, Morrisey EE, Foxp2 and Foxp1 cooperatively regulate lung and esophagus development. Development. 2007 May;134(10):1991-2000 |
1 | J:169693 Silberschmidt D, Rodriguez-Mallon A, Mithboakar P, Cali G, Amendola E, Sanges R, Zannini M, Scarfo M, De Luca P, Nitsch L, Di Lauro R, De Felice M, In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1. BMC Dev Biol. 2011;11:9 |
1 | J:171513 Tian Y, Zhang Y, Hurd L, Hannenhalli S, Liu F, Lu MM, Morrisey EE, Regulation of lung endoderm progenitor cell behavior by miR302/367. Development. 2011 Apr;138(7):1235-45 |
1* | J:141842 Tomita T, Kido T, Kurotani R, Iemura S, Sterneck E, Natsume T, Vinson C, Kimura S, CAATT/enhancer-binding proteins alpha and delta interact with NKX2-1 to synergistically activate mouse secretoglobin 3A2 gene expression. J Biol Chem. 2008 Sep 12;283(37):25617-27 |
1* | J:72724 Toresson H, Campbell K, A role for Gsh1 in the developing striatum and olfactory bulb of Gsh2 mutant mice. Development. 2001 Dec;128(23):4769-80 |
1 | J:83384 Tran PV, Lee MB, Marin O, Xu B, Jones KR, Reichardt LF, Rubenstein JR, Ingraham HA, Requirement of the orphan nuclear receptor SF-1 in terminal differentiation of ventromedial hypothalamic neurons. Mol Cell Neurosci. 2003 Apr;22(4):441-53 |
1 | J:266598 Ustiyan V, Bolte C, Zhang Y, Han L, Xu Y, Yutzey KE, Zorn AM, Kalin TV, Shannon JM, Kalinichenko VV, FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme. Dev Biol. 2018 Nov 1;443(1):50-63 |
1 | J:197638 van den Berghe V, Stappers E, Vandesande B, Dimidschstein J, Kroes R, Francis A, Conidi A, Lesage F, Dries R, Cazzola S, Berx G, Kessaris N, Vanderhaeghen P, van Ijcken W, Grosveld FG, Goossens S, Haigh JJ, Fishell G, Goffinet A, Aerts S, Huylebroeck D, Seuntjens E, Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1. Neuron. 2013 Jan 9;77(1):70-82 |
1 | J:317033 Xie C, Abrams SR, Herranz-Perez V, Garcia-Verdugo JM, Reiter JF, Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity. Dev Cell. 2021 Dec 20;56(24):3334-3348.e6 |
1 | J:247907 Yao J, Guihard PJ, Wu X, Blazquez-Medela AM, Spencer MJ, Jumabay M, Tontonoz P, Fogelman AM, Bostrom KI, Yao Y, Vascular endothelium plays a key role in directing pulmonary epithelial cell differentiation. J Cell Biol. 2017 Oct 02;216(10):3369-3385 |
1 | J:324465 Yu D, Li T, Delpech JC, Zhu B, Kishore P, Koshi T, Luo R, Pratt KJB, Popova G, Nowakowski TJ, Villeda SA, Piao X, Microglial GPR56 is the molecular target of maternal immune activation-induced parvalbumin-positive interneuron deficits. Sci Adv. 2022 May 6;8(18):eabm2545 |
2 | J:117072 Zhang Y, Rath N, Hannenhalli S, Wang Z, Cappola T, Kimura S, Atochina-Vasserman E, Lu MM, Beers MF, Morrisey EE, GATA and Nkx factors synergistically regulate tissue-specific gene expression and development in vivo. Development. 2007 Jan;134(1):189-98 |
Nkx2-2 NK2 homeobox 2 (Synonyms: Nkx-2.2, Nkx2.2, tinman) | |
Results | Reference |
1 | J:156329 Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L, Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. J Biol Chem. 2009 Nov 6;284(45):31236-48 |
1 | J:187468 Arnes L, Leclerc K, Friel JM, Hipkens SB, Magnuson MA, Sussel L, Generation of Nkx2.2:lacZ mice using recombination-mediated cassette exchange technology. Genesis. 2012 Aug;50(8):612-24 |
1 | J:226607 Clegg JM, Li Z, Molinek M, Caballero IM, Manuel MN, Price DJ, Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons. Neural Dev. 2015;10(1):26 |
1 | J:188332 Delogu A, Sellers K, Zagoraiou L, Bocianowska-Zbrog A, Mandal S, Guimera J, Rubenstein JL, Sugden D, Jessell T, Lumsden A, Subcortical visual shell nuclei targeted by ipRGCs develop from a Sox14+-GABAergic progenitor and require Sox14 to regulate daily activity rhythms. Neuron. 2012 Aug 23;75(4):648-62 |
1 | J:119914 Doyle MJ, Loomis ZL, Sussel L, Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet. Development. 2007 Feb;134(3):515-23 |
1* | J:74236 Fu H, Qi Y, Tan M, Cai J, Takebayashi H, Nakafuku M, Richardson W, Qiu M, Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation. Development. 2002 Feb;129(3):681-93 |
1 | J:170540 Jeong Y, Dolson DK, Waclaw RR, Matise MP, Sussel L, Campbell K, Kaestner KH, Epstein DJ, Spatial and temporal requirements for sonic hedgehog in the regulation of thalamic interneuron identity. Development. 2011 Feb;138(3):531-41 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1 | J:257425 Kim DS, Song L, Wang J, Wu H, Gu G, Sugi Y, Li Z, Wang H, GRP94 Is an Essential Regulator of Pancreatic beta-Cell Development, Mass, and Function in Male Mice. Endocrinology. 2018 Feb 1;159(2):1062-1073 |
1 | J:176201 Kordowich S, Collombat P, Mansouri A, Serup P, Arx and Nkx2.2 compound deficiency redirects pancreatic alpha- and beta-cell differentiation to a somatostatin/ghrelin co-expressing cell lineage. BMC Dev Biol. 2011;11:52 |
1 | J:235955 Laitman BM, Asp L, Mariani JN, Zhang J, Liu J, Sawai S, Chapouly C, Horng S, Kramer EG, Mitiku N, Loo H, Burlant N, Pedre X, Hara Y, Nudelman G, Zaslavsky E, Lee YM, Braun DA, Lu QR, Narla G, Raine CS, Friedman SL, Casaccia P, John GR, The Transcriptional Activator Kruppel-like Factor-6 Is Required for CNS Myelination. PLoS Biol. 2016 May;14(5):e1002467 |
2 | J:244498 Lee B, Lee M, Song S, Loi LD, Lam DT, Yoon J, Baek K, Curtis DJ, Jeong Y, Specification of neurotransmitter identity by Tal1 in thalamic nuclei. Dev Dyn. 2017 Oct;246(10):749-758 |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
1* | J:119850 Oh S, Huang X, Chiang C, Specific requirements of sonic hedgehog signaling during oligodendrocyte development. Dev Dyn. 2005 Nov;234(3):489-96 |
1 | J:162166 Peltopuro P, Kala K, Partanen J, Distinct requirements for Ascl1 in subpopulations of midbrain GABAergic neurons. Dev Biol. 2010 Jul 1;343(1-2):63-70 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:84301 Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M, The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 2003 Jul 1;17(13):1677-89 |
1 | J:135661 Sugimori M, Nagao M, Parras CM, Nakatani H, Lebel M, Guillemot F, Nakafuku M, Ascl1 is required for oligodendrocyte development in the spinal cord. Development. 2008 Apr;135(7):1271-81 |
1* | J:287411 Tran HN, Park W, Seong S, Jeong JE, Nguyen QH, Yoon J, Baek K, Jeong Y, Tcf7l2 transcription factor is required for the maintenance, but not the initial specification, of the neurotransmitter identity in the caudal thalamus. Dev Dyn. 2020 May;249(5):646-655 |
1 | J:132518 Vue TY, Aaker J, Taniguchi A, Kazemzadeh C, Skidmore JM, Martin DM, Martin JF, Treier M, Nakagawa Y, Characterization of progenitor domains in the developing mouse thalamus. J Comp Neurol. 2007 Nov 1;505(1):73-91 |
1 | J:147427 Vue TY, Bluske K, Alishahi A, Yang LL, Koyano-Nakagawa N, Novitch B, Nakagawa Y, Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice. J Neurosci. 2009 Apr 8;29(14):4484-97 |
1 | J:362739 Wu Y, Qin K, Xu Y, Rajhans S, Vo T, Lopez KM, Liu J, Nipper MH, Deng J, Yin X, Ramjit LR, Ye Z, Luan Y, Arda HE, Wang P, Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation. Elife. 2024 Jul 25;13 |
Nkx2-5 NK2 homeobox 5 (Synonyms: Csx, Nkx-2.5, Nkx2.5, tinman) | |
Results | Reference |
1 | J:173586 Hahurij ND, Kolditz DP, Bokenkamp R, Markwald RR, Schalij MJ, Poelmann RE, Gittenberger-DE Groot AC, Blom NA, Accessory atrioventricular myocardial pathways in mouse heart development: substrate for supraventricular tachycardias. Pediatr Res. 2011 Jul;70(1):37-43 |
1* | J:92209 Huang F, Wagner M, Siddiqui MA, Ablation of the CLP-1 gene leads to down-regulation of the HAND1 gene and abnormality of the left ventricle of the heart and fetal death. Mech Dev. 2004 Jun;121(6):559-72 |
1 | J:183651 Kim EY, Chen L, Ma Y, Yu W, Chang J, Moskowitz IP, Wang J, Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J Mol Cell Cardiol. 2012 Mar;52(3):638-49 |
1 | J:184521 Koss M, Bolze A, Brendolan A, Saggese M, Capellini TD, Bojilova E, Boisson B, Prall OW, Elliott DA, Solloway M, Lenti E, Hidaka C, Chang CP, Mahlaoui N, Harvey RP, Casanova JL, Selleri L, Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module. Dev Cell. 2012 May 15;22(5):913-26 |
1 | J:310382 Liu Z, Vong QP, Liu C, Zheng Y, Borg5 is required for angiogenesis by regulating persistent directional migration of the cardiac microvascular endothelial cells. Mol Biol Cell. 2014 Mar;25(6):841-51 |
1 | J:122971 Moskowitz IP, Kim JB, Moore ML, Wolf CM, Peterson MA, Shendure J, Nobrega MA, Yokota Y, Berul C, Izumo S, Seidman JG, Seidman CE, A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development. Cell. 2007 Jun 29;129(7):1365-76 |
1 | J:288301 Mu Y, Yu H, Wu T, Zhang J, Evans SM, Chen J, O-linked beta-N-acetylglucosamine transferase plays an essential role in heart development through regulating angiopoietin-1. PLoS Genet. 2020 Apr;16(4):e1008730 |
1 | J:221833 Prakash A, Udager AM, Saenz DA, Gumucio DL, Roles for Nkx2-5 and Gata3 in the ontogeny of the murine smooth muscle gastric ligaments. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 15;307(4):G430-6 |
1 | J:101739 Takeuchi JK, Mileikovskaia M, Koshiba-Takeuchi K, Heidt AB, Mori AD, Arruda EP, Gertsenstein M, Georges R, Davidson L, Mo R, Hui CC, Henkelman RM, Nemer M, Black BL, Nagy A, Bruneau BG, Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development. Development. 2005 May;132(10):2463-74 |
1 | J:228275 Udager AM, Prakash A, Saenz DA, Schinke M, Moriguchi T, Jay PY, Lim KC, Engel JD, Gumucio DL, Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3. Gastroenterology. 2014 Jan;146(1):157-65.e10 |
1 | J:253740 Yan J, Zhang L, Sultana N, Oh JG, Wu B, Hajjar RJ, Zhou B, Cai CL, A series of robust genetic indicators for definitive identification of cardiomyocytes. J Mol Cell Cardiol. 2016 Aug;97:278-85 |
1 | J:226315 Ye W, Wang J, Song Y, Yu D, Sun C, Liu C, Chen F, Zhang Y, Wang F, Harvey RP, Schrader L, Martin JF, Chen Y, A common Shox2-Nkx2-5 antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node. Development. 2015 Jul 15;142(14):2521-32 |
Nkx2-6 NK2 homeobox 6 (Synonyms: Nkx-2.6, Nkx2.6, tinman, Tix) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Nkx3-1 NK3 homeobox 1 (Synonyms: bagpipe, Bax, Nkx-3.1, NKX3.1, NKX3A) | |
Results | Reference |
1* | J:54465 Bhatia-Gaur R, Donjacour AA, Sciavolino PJ, Kim M, Desai N, Young P, Norton CR, Gridley T, Cardiff RD, Cunha GR, Abate-Shen C, Shen MM, Roles for Nkx3.1 in prostate development and cancer. Genes Dev. 1999 Apr 15;13(8):966-77 |
1* | J:306453 Kajioka D, Suzuki K, Matsushita S, Hino S, Sato T, Takada S, Isono K, Takeo T, Kajimoto M, Nakagata N, Nakao M, Suyama M, DeFalco T, Miyagawa S, Yamada G, Sexual fate of murine external genitalia development: Conserved transcriptional competency for male-biased genes in both sexes. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2024067118 |
1* | J:187370 Keil KP, Mehta V, Abler LL, Joshi PS, Schmitz CT, Vezina CM, Visualization and quantification of mouse prostate development by in situ hybridization. Differentiation. 2012 Oct;84(3):232-9 |
1* | J:192625 Keil KP, Mehta V, Branam AM, Abler LL, Buresh-Stiemke RA, Joshi PS, Schmitz CT, Marker PC, Vezina CM, Wnt inhibitory factor 1 (Wif1) is regulated by androgens and enhances androgen-dependent prostate development. Endocrinology. 2012 Dec;153(12):6091-103 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1* | J:240534 Toivanen R, Shen MM, Prostate organogenesis: tissue induction, hormonal regulation and cell type specification. Development. 2017 Apr 15;144(8):1382-1398 |
Nkx3-2 NK3 homeobox 2 (Synonyms: Bapx1, Nkx-3.2) | |
Results | Reference |
1 | J:185430 Choi SW, Jeong DU, Kim JA, Lee B, Joeng KS, Long F, Kim DW, Indian Hedgehog signalling triggers Nkx3.2 protein degradation during chondrocyte maturation. Biochem J. 2012 May 1;443(3):789-98 |
1 | J:99641 Kobayashi T, Soegiarto DW, Yang Y, Lanske B, Schipani E, McMahon AP, Kronenberg HM, Indian hedgehog stimulates periarticular chondrocyte differentiation to regulate growth plate length independently of PTHrP. J Clin Invest. 2005 Jul;115(7):1734-42 |
1* | J:42036 Tribioli C, Frasch M, Lufkin T, Bapx1: an evolutionary conserved homologue of the Drosophila bagpipe homeobox gene is expressed in splanchnic mesoderm and the embryonic skeleton. Mech Dev. 1997 Jul;65(1-2):145-62 |
Nkx6-1 NK6 homeobox 1 (Synonyms: Nkx6.1, NKX6A) | |
Results | Reference |
1* | J:104158 Alanentalo T, Chatonnet F, Karlen M, Sulniute R, Ericson J, Andersson E, Ahlgren U, Cloning and analysis of Nkx6.3 during CNS and gastrointestinal development. Gene Expr Patterns. 2006 Jan;6(2):162-70 |
1 | J:327292 Bakhti M, Bastidas-Ponce A, Tritschler S, Czarnecki O, Tarquis-Medina M, Nedvedova E, Jaki J, Willmann SJ, Scheibner K, Cota P, Salinno C, Boldt K, Horn N, Ueffing M, Burtscher I, Theis FJ, Coskun U, Lickert H, Synaptotagmin-13 orchestrates pancreatic endocrine cell egression and islet morphogenesis. Nat Commun. 2022 Aug 4;13(1):4540 |
1 | J:307544 Burtscher I, Tarquis-Medina M, Salinno C, Schirge S, Beckenbauer J, Bakhti M, Lickert H, Generation of a Novel Nkx6-1 Venus Fusion Reporter Mouse Line. Int J Mol Sci. 2021 Mar 26;22(7) |
1 | J:200985 Cai EP, Wu X, Schroer SA, Elia AJ, Nostro MC, Zacksenhaus E, Woo M, Retinoblastoma tumor suppressor protein in pancreatic progenitors controls alpha- and beta-cell fate. Proc Natl Acad Sci U S A. 2013 Sep 3;110(36):14723-8 |
1 | J:346123 Darrigrand JF, Salowka A, Torres-Cano A, Tapia-Rojo R, Zhu T, Garcia-Manyes S, Spagnoli FM, Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner. Dev Cell. 2024 Feb 5;59(3):326-338.e5 |
1 | J:275470 Hirata K, Kodama S, Nakano Y, Minaki-Nakagawa Y, Aoyama Y, Sakikubo M, Goto T, Yoshida M, Masui T, Yamamoto T, Uemoto S, Kawaguchi Y, Exocrine tissue-driven TFF2 prevents apoptotic cell death of endocrine lineage during pancreas organogenesis. Sci Rep. 2019 Feb 7;9(1):1636 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1 | J:257425 Kim DS, Song L, Wang J, Wu H, Gu G, Sugi Y, Li Z, Wang H, GRP94 Is an Essential Regulator of Pancreatic beta-Cell Development, Mass, and Function in Male Mice. Endocrinology. 2018 Feb 1;159(2):1062-1073 |
1 | J:239986 Lahti L, Haugas M, Tikker L, Airavaara M, Voutilainen MH, Anttila J, Kumar S, Inkinen C, Salminen M, Partanen J, Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei. Development. 2016 Feb 01;143(3):516-29 |
1 | J:122518 Nelson SB, Schaffer AE, Sander M, The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting beta-cell fate specification in Pdx1+ pancreatic progenitor cells. Development. 2007 Jul;134(13):2491-500 |
1 | J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Nkx6-2 NK6 homeobox 2 (Synonyms: Gtx, Nkx6.2) | |
Results | Reference |
1* | J:104158 Alanentalo T, Chatonnet F, Karlen M, Sulniute R, Ericson J, Andersson E, Ahlgren U, Cloning and analysis of Nkx6.3 during CNS and gastrointestinal development. Gene Expr Patterns. 2006 Jan;6(2):162-70 |
1 | J:354217 Ohyama K, Shinohara HM, Takayama N, Ogawa R, Omura S, Hayashida M, Takahashi T, Differentiation stage-specific expression of transcriptional regulators for epithelial mesenchymal transition in dentate granule progenitors. Front Neurosci. 2024;18:1425849 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Nkx6-3 NK6 homeobox 3 (Synonyms: 9130417I07Rik, Nkx6.3) | |
Results | Reference |
1* | J:104158 Alanentalo T, Chatonnet F, Karlen M, Sulniute R, Ericson J, Andersson E, Ahlgren U, Cloning and analysis of Nkx6.3 during CNS and gastrointestinal development. Gene Expr Patterns. 2006 Jan;6(2):162-70 |
Nlk nemo like kinase | |
Results | Reference |
1* | J:45651 Brott BK, Pinsky BA, Erikson RL, Nlk is a murine protein kinase related to Erk/MAP kinases and localized in the nucleus. Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):963-8 |
Nlrp5 NLR family, pyrin domain containing 5 (Synonyms: Mater, Nalp5, Op1) | |
Results | Reference |
1 | J:326570 Niu W, Spradling AC, Mouse oocytes develop in cysts with the help of nurse cells. Cell. 2022 Jul 7;185(14):2576-2590.e12 |
Nlrp10 NLR family, pyrin domain containing 10 (Synonyms: 6430548I20Rik, Nalp10, Pynod) | |
Results | Reference |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Nme5 NME/NM23 family member 5 (Synonyms: 1700019D05Rik, Nm23-M5, non-metastatic cells 5, protein expressed in (nucleoside-diphosphate kinase)) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Nmral1 NmrA-like family domain containing 1 (Synonyms: 1110025F24Rik) | |
Results | Reference |
2* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
Nms neuromedin S | |
Results | Reference |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
Nnat neuronatin (Synonyms: 5730414I02Rik, Peg5) | |
Results | Reference |
2 | J:105207 Chu K, Tsai MJ, Neuronatin, a downstream target of BETA2/NeuroD1 in the pancreas, is involved in glucose-mediated insulin secretion. Diabetes. 2005 Apr;54(4):1064-73 |
1* | J:29420 Wijnholds J, Chowdhury K, Wehr R, Gruss P, Segment-specific expression of the neuronatin gene during early hindbrain development. Dev Biol. 1995 Sep;171(1):73-84 |
Nobox NOBOX oogenesis homeobox (Synonyms: Og2x) | |
Results | Reference |
1 | J:326570 Niu W, Spradling AC, Mouse oocytes develop in cysts with the help of nurse cells. Cell. 2022 Jul 7;185(14):2576-2590.e12 |
2 | J:244395 Shin YH, Ren Y, Suzuki H, Golnoski KJ, Ahn HW, Mico V, Rajkovic A, Transcription factors SOHLH1 and SOHLH2 coordinate oocyte differentiation without affecting meiosis I. J Clin Invest. 2017 Jun 01;127(6):2106-2117 |
1 | J:297097 Sorrenti M, Klinger FG, Iona S, Rossi V, Marcozzi S, DE Felici M, Expression and possible roles of extracellular signal-related kinases 1-2 (ERK1-2) in mouse primordial germ cell development. J Reprod Dev. 2020 Oct 13;66(5):399-409 |
Noc2l NOC2 like nucleolar associated transcriptional repressor (Synonyms: NIR) | |
Results | Reference |
1 | J:260456 Duteil D, Tourrette Y, Eberlin A, Willmann D, Patel D, Friedrichs N, Muller JM, Schule R, The histone acetyltransferase inhibitor Nir regulates epidermis development. Development. 2018 Mar 21;145(6):dev158543 |
1* | J:103923 Hublitz P, Kunowska N, Mayer UP, Muller JM, Heyne K, Yin N, Fritzsche C, Poli C, Miguet L, Schupp IW, van Grunsven LA, Potiers N, van Dorsselaer A, Metzger E, Roemer K, Schule R, NIR is a novel INHAT repressor that modulates the transcriptional activity of p53. Genes Dev. 2005 Dec 1;19(23):2912-24 |
Noc3l NOC3 like DNA replication regulator (Synonyms: Fad24) | |
Results | Reference |
1* | J:66491 Tidhar A, Reichenstein M, Cohen D, Faerman A, Copeland NG, Gilbert DJ, Jenkins NA, Shani M, A novel transgenic marker for migrating limb muscle precursors and for vascular smooth muscle cells. Dev Dyn. 2001 Jan;220(1):60-73 |
Nodal nodal growth differentiation factor (Synonyms: Tg.413d) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:320172 Souquet B, Tourpin S, Messiaen S, Moison D, Habert R, Livera G, Nodal signaling regulates the entry into meiosis in fetal germ cells. Endocrinology. 2012 May;153(5):2466-73 |
Nog noggin | |
Results | Reference |
1* | J:75699 Albrecht AN, Schwabe GC, Stricker S, Boddrich A, Wanker EE, Mundlos S, The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67 |
1 | J:126342 Bok J, Brunet LJ, Howard O, Burton Q, Wu DK, Role of hindbrain in inner ear morphogenesis: Analysis of Noggin knockout mice. Dev Biol. 2007 Nov 1;311(1):69-78 |
1 | J:130204 Cook C, Vezina CM, Allgeier SH, Shaw A, Yu M, Peterson RE, Bushman W, Noggin is required for normal lobe patterning and ductal budding in the mouse prostate. Dev Biol. 2007 Dec 1;312(1):217-30 |
1 | J:217500 Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D, Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60 |
2 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1* | J:236374 Goldie SJ, Arhatari BD, Anderson P, Auden A, Partridge DD, Jane SM, Dworkin S, Mice lacking the conserved transcription factor Grainyhead-like 3 (Grhl3) display increased apposition of the frontal and parietal bones during embryonic development. BMC Dev Biol. 2016 Oct 18;16(1):37 |
1* | J:156945 Hwang CH, Guo D, Harris MA, Howard O, Mishina Y, Gan L, Harris SE, Wu DK, Role of bone morphogenetic proteins on cochlear hair cell formation: analyses of Noggin and Bmp2 mutant mice. Dev Dyn. 2010 Feb;239(2):505-13 |
2* | J:132023 Hwang CH, Wu DK, Noggin heterozygous mice: an animal model for congenital conductive hearing loss in humans. Hum Mol Genet. 2008 Mar 15;17(6):844-53 |
1 | J:265947 Kawasaki M, Kawasaki K, Meguro F, Yamada A, Ishikawa R, Porntaveetus T, Blackburn J, Otsuka-Tanaka Y, Saito N, Ota MS, Sharpe PT, Kessler JA, Herz J, Cobourne MT, Maeda T, Ohazama A, Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms. PLoS One. 2018;13(9):e0204126 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
2 | J:134924 Spagnoli A, O'Rear L, Chandler RL, Granero-Molto F, Mortlock DP, Gorska AE, Weis JA, Longobardi L, Chytil A, Shimer K, Moses HL, TGF-beta signaling is essential for joint morphogenesis. J Cell Biol. 2007 Jun 18;177(6):1105-17 |
1 | J:144194 Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72 |
1 | J:159209 Tornqvist G, Sandberg A, Hagglund AC, Carlsson L, Cyclic expression of lhx2 regulates hair formation. PLoS Genet. 2010;6(4):e1000904 |
Nol3 nucleolar protein 3 (apoptosis repressor with CARD domain) (Synonyms: ARC, B430311C09Rik, Nop30) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Nos1 nitric oxide synthase 1, neuronal (Synonyms: 2310005C01Rik, bNOS, nNOS, NO, Nos-1) | |
Results | Reference |
1 | J:105292 Anderson RB, Stewart AL, Young HM, Phenotypes of neural-crest-derived cells in vagal and sacral pathways. Cell Tissue Res. 2006 Jan;323(1):11-25 |
1* | J:96845 Arnhold S, When M, Labbe D, Andressen C, Addicks K, Transient expression of NOS-II during development of the murine enteric nervous system. J Mol Histol. 2004 Nov;35(8-9):741-8 |
1* | J:31707 Bruning G, Mayer B, Prenatal development of nitric oxide synthase in the mouse spinal cord. Neurosci Lett. 1996 Jan 5;202(3):189-92 |
1 | J:85092 Funakoshi K, Goris RC, Kadota T, Atobe Y, Nakano M, Kishida R, Prenatal development of peptidergic primary afferent projections to mouse lumbosacral autonomic preganglionic cell columns. Brain Res Dev Brain Res. 2003 Aug 12;144(1):107-19 |
1 | J:114546 Funakoshi K, Nakano M, Atobe Y, Kadota T, Goris RC, Prenatal development of transient receptor potential vanilloid 1-expressing primary sensory projections to sacral autonomic preganglionic neurons. Neurosci Lett. 2006 Oct 30;407(3):230-3 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1 | J:202183 Hao MM, Bornstein JC, Young HM, Development of myenteric cholinergic neurons in ChAT-Cre;R26R-YFP mice. J Comp Neurol. 2013 Oct 1;521(14):3358-70 |
1 | J:306265 Hao MM, Fung C, Boesmans W, Lowette K, Tack J, Vanden Berghe P, Development of the intrinsic innervation of the small bowel mucosa and villi. Am J Physiol Gastrointest Liver Physiol. 2020 Jan 1;318(1):G53-G65 |
1 | J:55749 Oermann E, Bidmon HJ, Mayer B, Zilles K, Differential maturational patterns of nitric oxide synthase-I and NADPH diaphorase in functionally distinct cortical areas of the mouse cerebral cortex. Anat Embryol (Berl). 1999 Jul;200(1):27-41 |
1* | J:95790 Richard C, Gao J, LaFleur B, Christman BW, Anderson J, Brown N, Reese J, Patency of the preterm fetal ductus arteriosus is regulated by endothelial nitric oxide synthase and is independent of vasa vasorum in the mouse. Am J Physiol Regul Integr Comp Physiol. 2004 Sep;287(3):R652-60 |
1* | J:42766 Sang Q, Young HM, Development of nicotinic receptor clusters and innervation accompanying the change in muscle phenotype in the mouse esophagus. J Comp Neurol. 1997 Sep 15;386(1):119-36 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:47865 Young HM, Ciampoli D, Transient expression of neuronal nitric oxide synthase by neurons of the submucous plexus of the mouse small intestine. Cell Tissue Res. 1998 Mar;291(3):395-401 |
Nos2 nitric oxide synthase 2, inducible (Synonyms: iNOS, Nos-2, Nos2a, NOS-II) | |
Results | Reference |
1* | J:96845 Arnhold S, When M, Labbe D, Andressen C, Addicks K, Transient expression of NOS-II during development of the murine enteric nervous system. J Mol Histol. 2004 Nov;35(8-9):741-8 |
1 | J:170178 Kobayashi K, Umezawa K, Yasui M, Apoptosis in mouse amniotic epithelium is induced by activated macrophages through the TNF receptor type 1/TNF pathway. Biol Reprod. 2011 Feb;84(2):248-54 |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1* | J:95790 Richard C, Gao J, LaFleur B, Christman BW, Anderson J, Brown N, Reese J, Patency of the preterm fetal ductus arteriosus is regulated by endothelial nitric oxide synthase and is independent of vasa vasorum in the mouse. Am J Physiol Regul Integr Comp Physiol. 2004 Sep;287(3):R652-60 |
Nos3 nitric oxide synthase 3, endothelial cell (Synonyms: 2310065A03Rik, ecNOS, eNOS, Nos-3) | |
Results | Reference |
1* | J:96845 Arnhold S, When M, Labbe D, Andressen C, Addicks K, Transient expression of NOS-II during development of the murine enteric nervous system. J Mol Histol. 2004 Nov;35(8-9):741-8 |
1 | J:341378 Iyer D, Mastrogiacomo DM, Li K, Banerjee R, Yang Y, Scallan JP, eNOS Regulates Lymphatic Valve Specification by Controlling beta-Catenin Signaling During Embryogenesis in Mice. Arterioscler Thromb Vasc Biol. 2023 Sep 28; |
1* | J:95790 Richard C, Gao J, LaFleur B, Christman BW, Anderson J, Brown N, Reese J, Patency of the preterm fetal ductus arteriosus is regulated by endothelial nitric oxide synthase and is independent of vasa vasorum in the mouse. Am J Physiol Regul Integr Comp Physiol. 2004 Sep;287(3):R652-60 |
1 | J:181330 Sabine A, Agalarov Y, Maby-El Hajjami H, Jaquet M, Hagerling R, Pollmann C, Bebber D, Pfenniger A, Miura N, Dormond O, Calmes JM, Adams RH, Makinen T, Kiefer F, Kwak BR, Petrova TV, Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation. Dev Cell. 2012 Feb 14;22(2):430-45 |
1 | J:124878 Sierro F, Biben C, Martinez-Munoz L, Mellado M, Ransohoff RM, Li M, Woehl B, Leung H, Groom J, Batten M, Harvey RP, Martinez-A C, Mackay CR, Mackay F, Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14759-64 |
Notch1 notch 1 (Synonyms: 9930111A19Rik, lin-12, Mis6, Motch A, N1, Tan1) | |
Results | Reference |
1 | J:60107 Allen T, Lobe CG, A comparison of Notch, Hes and Grg expression during murine embryonic and post-natal development. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):687-708 |
1 | J:310741 Briot A, Jaroszewicz A, Warren CM, Lu J, Touma M, Rudat C, Hofmann JJ, Airik R, Weinmaster G, Lyons K, Wang Y, Kispert A, Pellegrini M, Iruela-Arispe ML, Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Dev Cell. 2014 Dec 22;31(6):707-21 |
1* | J:229936 Cano E, Carmona R, Ruiz-Villalba A, Rojas A, Chau YY, Wagner KD, Wagner N, Hastie ND, Munoz-Chapuli R, Perez-Pomares JM, Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):656-61 |
1* | J:184017 Chi Z, Zhang J, Tokunaga A, Harraz MM, Byrne ST, Dolinko A, Xu J, Blackshaw S, Gaiano N, Dawson TM, Dawson VL, Botch promotes neurogenesis by antagonizing Notch. Dev Cell. 2012 Apr 17;22(4):707-20 |
1 | J:205488 Chin SS, Romano RA, Nagarajan P, Sinha S, Garrett-Sinha LA, Aberrant epidermal differentiation and disrupted DeltaNp63/Notch regulatory axis in Ets1 transgenic mice. Biol Open. 2013;2(12):1336-45 |
1 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1* | J:1679 Del Amo FF, Smith DE, Swiatek PJ, Gendron-Maguire M, Greenspan RJ, McMahon AP, Gridley T, Expression pattern of Motch, a mouse homolog of Drosophila Notch, suggests an important role in early postimplantation mouse development. Development. 1992 Jul;115(3):737-44 |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
3 | J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109 |
1 | J:172287 Esteve P, Sandonis A, Cardozo M, Malapeira J, Ibanez C, Crespo I, Marcos S, Gonzalez-Garcia S, Toribio ML, Arribas J, Shimono A, Guerrero I, Bovolenta P, SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis. Nat Neurosci. 2011 May;14(5):562-9 |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1 | J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489 |
1 | J:63320 Favier B, Fliniaux I, Thelu J, Viallet JP, Demarchez M, Jahoda CA, Dhouailly D, Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators. Dev Dyn. 2000 Jul;218(3):426-37 |
1 | J:62563 Gaiano N, Nye JS, Fishell G, Radial glial identity is promoted by Notch1 signaling in the murine forebrain. Neuron. 2000 May;26(2):395-404 |
1 | J:183603 Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A, Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res. 2011 Apr 1;108(7):813-23 |
1 | J:104840 Grishina IB, Kim SY, Ferrara C, Makarenkova HP, Walden PD, BMP7 inhibits branching morphogenesis in the prostate gland and interferes with Notch signaling. Dev Biol. 2005 Dec 15;288(2):334-47 |
1 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
1 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1* | J:339600 Hermosilla Aguayo V, Martin P, Tian N, Zheng J, Aho R, Losa M, Selleri L, ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:64088 Ito T, Udaka N, Yazawa T, Okudela K, Hayashi H, Sudo T, Guillemot F, Kageyama R, Kitamura H, Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development. 2000 Sep;127(18):3913-21 |
1 | J:239364 Ivins S, Chappell J, Vernay B, Suntharalingham J, Martineau A, Mohun TJ, Scambler PJ, The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development. Dev Cell. 2015 May 26;33(4):455-68 |
1 | J:304850 Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernandez-Baldovinos J, Zhou L, Hoss C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Grone HJ, Graumann PL, Niessen CM, Offermanns S, Wickstrom SA, Worzfeld T, Mechanochemical control of epidermal stem cell divisions by B-plexins. Nat Commun. 2021 Feb 26;12(1):1308 |
1 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
1* | J:35621 Koop KE, MacDonald LM, Lobe CG, Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development. Mech Dev. 1996 Sep;59(1):73-87 |
1 | J:195630 Krolewski RC, Packard A, Jang W, Wildner H, Schwob JE, Ascl1 (Mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium. PLoS One. 2012;7(12):e51737 |
2* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670 |
1 | J:183997 Langer L, Taranova O, Sulik K, Pevny L, SOX2 hypomorphism disrupts development of the prechordal floor and optic cup. Mech Dev. 2012 Mar;129(1-4):1-12 |
1 | J:86441 Lin MH, Kopan R, Long-range, nonautonomous effects of activated Notch1 on tissue homeostasis in the nail. Dev Biol. 2003 Nov 15;263(2):343-59 |
1 | J:335167 Lu P, Wu B, Wang Y, Russell M, Liu Y, Bernard DJ, Zheng D, Zhou B, Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis. Dev Cell. 2023 Mar 29; |
1 | J:171254 Matsumoto A, Onoyama I, Sunabori T, Kageyama R, Okano H, Nakayama KI, Fbxw7-dependent Degradation of Notch Is Required for Control of 'Stemness' and Neuronal-Glial Differentiation in Neural Stem Cells. J Biol Chem. 2011 Apr 15;286(15):13754-64 |
1 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
1 | J:332403 Miller SR, Perera SN, Benito C, Stott SR, Baker CV, Evidence for a Notch1-mediated transition during olfactory ensheathing cell development. J Anat. 2016 Sep;229(3):369-83 |
1* | J:73301 Mitsiadis TA, Gayet O, Zhang N, Carroll P, Expression of Deltex1 during mouse embryogenesis: comparison with Notch1, 2 and 3 expression. Mech Dev. 2001 Dec;109(2):399-403 |
1 | J:51928 Mitsiadis TA, Hirsinger E, Lendahl U, Goridis C, Delta-notch signaling in odontogenesis: correlation with cytodifferentiation and evidence for feedback regulation. Dev Biol. 1998 Dec 15;204(2):420-31 |
1 | J:26831 Mitsiadis TA, Lardelli M, Lendahl U, Thesleff I, Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate. J Cell Biol. 1995 Jul;130(2):407-18 |
1 | J:339608 Mitsiadis TA, Pagella P, Capellini TD, Smith MM, The Notch-mediated circuitry in the evolution and generation of new cell lineages: the tooth model. Cell Mol Life Sci. 2023 Jun 18;80(7):182 |
1 | J:156690 Morimoto M, Liu Z, Cheng HT, Winters N, Bader D, Kopan R, Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate. J Cell Sci. 2010 Jan 15;123(Pt 2):213-24 |
1 | J:143162 Murata J, Tokunaga A, Okano H, Kubo T, Mapping of notch activation during cochlear development in mice: implications for determination of prosensory domain and cell fate diversification. J Comp Neurol. 2006 Jul 20;497(3):502-18 |
1 | J:213874 Murtomaki A, Uh MK, Kitajewski C, Zhao J, Nagasaki T, Shawber CJ, Kitajewski J, Notch signaling functions in lymphatic valve formation. Development. 2014 Jun;141(12):2446-51 |
1 | J:309437 Nakagawa N, Li J, Yabuno-Nakagawa K, Eom TY, Cowles M, Mapp T, Taylor R, Anton ES, APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017 Aug 15;31(16):1679-1692 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
1 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1* | J:3293 Reaume AG, Conlon RA, Zirngibl R, Yamaguchi TP, Rossant J, Expression analysis of a Notch homologue in the mouse embryo. Dev Biol. 1992 Dec;154(2):377-87 |
1 | J:330615 Rim JH, Noh B, Koh YI, Joo SY, Oh KS, Kim K, Kim JA, Kim DH, Kim HY, Yoo JE, Lee ST, Bok JW, Lee MG, Jung J, Choi JY, Gee HY, Differential genetic diagnoses of adult post-lingual hearing loss according to the audiogram pattern and novel candidate gene evaluation. Hum Genet. 2022 Apr;141(3-4):915-927 |
1 | J:124878 Sierro F, Biben C, Martinez-Munoz L, Mellado M, Ransohoff RM, Li M, Woehl B, Leung H, Groom J, Batten M, Harvey RP, Martinez-A C, Mackay CR, Mackay F, Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14759-64 |
1 | J:91404 Tokunaga A, Kohyama J, Yoshida T, Nakao K, Sawamoto K, Okano H, Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain. J Neurochem. 2004 Jul;90(1):142-54 |
3 | J:320173 Traustadottir GA, Jensen CH, Thomassen M, Beck HC, Mortensen SB, Laborda J, Baladron V, Sheikh SP, Andersen DC, Evidence of non-canonical NOTCH signaling: Delta-like 1 homolog (DLK1) directly interacts with the NOTCH1 receptor in mammals. Cell Signal. 2016 Apr;28(4):246-54 |
1 | J:299728 Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL, Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. Elife. 2019 Dec 4;8:e49977 |
1 | J:213069 Vanorny DA, Prasasya RD, Chalpe AJ, Kilen SM, Mayo KE, Notch signaling regulates ovarian follicle formation and coordinates follicular growth. Mol Endocrinol. 2014 Apr;28(4):499-511 |
1 | J:236342 Wang W, Jossin Y, Chai G, Lien WH, Tissir F, Goffinet AM, Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun. 2016 Mar 04;7:10936 |
1 | J:261826 Wang Y, Wu B, Farrar E, Lui W, Lu P, Zhang D, Alfieri CM, Mao K, Chu M, Yang D, Xu D, Rauchman M, Taylor V, Conway SJ, Yutzey KE, Butcher JT, Zhou B, Notch-Tnf signalling is required for development and homeostasis of arterial valves. Eur Heart J. 2017 Mar 1;38(9):675-686 |
1 | J:86343 Watanabe N, Tezuka Y, Matsuno K, Miyatani S, Morimura N, Yasuda M, Fujimaki R, Kuroda K, Hiraki Y, Hozumi N, Tezuka K, Suppression of differentiation and proliferation of early chondrogenic cells by Notch. J Bone Miner Metab. 2003;21(6):344-52 |
1* | J:214228 Weaver KL, Alves-Guerra MC, Jin K, Wang Z, Han X, Ranganathan P, Zhu X, DaSilva T, Liu W, Ratti F, Demarest RM, Tzimas C, Rice M, Vasquez-Del Carpio R, Dahmane N, Robbins DJ, Capobianco AJ, NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis. Cancer Res. 2014 Sep 1;74(17):4741-51 |
2 | J:155893 Xu K, Nieuwenhuis E, Cohen BL, Wang W, Canty AJ, Danska JS, Coultas L, Rossant J, Wu MY, Piscione TD, Nagy A, Gossler A, Hicks GG, Hui CC, Henkelman RM, Yu LX, Sled JG, Gridley T, Egan SE, Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis. Am J Physiol Lung Cell Mol Physiol. 2010 Jan;298(1):L45-56 |
2 | J:225082 Zhang LJ, Bhattacharya S, Leid M, Ganguli-Indra G, Indra AK, Ctip2 is a dynamic regulator of epidermal proliferation and differentiation by integrating EGFR and Notch signaling. J Cell Sci. 2012 Dec 1;125(Pt 23):5733-44 |
1* | J:173972 Zhao H, Li S, Han D, Kaartinen V, Chai Y, Alk5-mediated transforming growth factor beta signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol. 2011 May;31(10):2079-89 |
1 | J:316098 Zhao J, Lu P, Wan C, Huang Y, Cui M, Yang X, Hu Y, Zheng Y, Dong J, Wang M, Zhang S, Liu Z, Bian S, Wang X, Wang R, Ren S, Wang D, Yao Z, Chang G, Tang F, Zhao XY, Cell-fate transition and determination analysis of mouse male germ cells throughout development. Nat Commun. 2021 Nov 25;12(1):6839 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Notch2 notch 2 (Synonyms: Motch B, N2) | |
Results | Reference |
1 | J:173587 Chen W, Jiang H, Wang M, Jin J, Feng S, Bi Y, Wang H, Mao Y, Shou Z, Chen J, Effects of chlorpyrifos exposure on kidney Notch2-Jagged1 pathway of early prenatal embryo. Birth Defects Res B Dev Reprod Toxicol. 2011 Apr;92(2):97-101 |
1 | J:63320 Favier B, Fliniaux I, Thelu J, Viallet JP, Demarchez M, Jahoda CA, Dhouailly D, Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators. Dev Dyn. 2000 Jul;218(3):426-37 |
1 | J:183603 Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A, Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res. 2011 Apr 1;108(7):813-23 |
1 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:64088 Ito T, Udaka N, Yazawa T, Okudela K, Hayashi H, Sudo T, Guillemot F, Kageyama R, Kitamura H, Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development. 2000 Sep;127(18):3913-21 |
1 | J:154589 Jeong HW, Jeon US, Koo BK, Kim WY, Im SK, Shin J, Cho Y, Kim J, Kong YY, Inactivation of Notch signaling in the renal collecting duct causes nephrogenic diabetes insipidus in mice. J Clin Invest. 2009 Nov;119(11):3290-300 |
1 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
2 | J:257613 Kuony A, Michon F, Epithelial Markers aSMA, Krt14, and Krt19 Unveil Elements of Murine Lacrimal Gland Morphogenesis and Maturation. Front Physiol. 2017;8:739 |
2* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1* | J:67157 McCright B, Gao X, Shen L, Lozier J, Lan Y, Maguire M, Herzlinger D, Weinmaster G, Jiang R, Gridley T, Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development. 2001 Feb;128(4):491-502 |
1 | J:51928 Mitsiadis TA, Hirsinger E, Lendahl U, Goridis C, Delta-notch signaling in odontogenesis: correlation with cytodifferentiation and evidence for feedback regulation. Dev Biol. 1998 Dec 15;204(2):420-31 |
1 | J:26831 Mitsiadis TA, Lardelli M, Lendahl U, Thesleff I, Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate. J Cell Biol. 1995 Jul;130(2):407-18 |
1 | J:339608 Mitsiadis TA, Pagella P, Capellini TD, Smith MM, The Notch-mediated circuitry in the evolution and generation of new cell lineages: the tooth model. Cell Mol Life Sci. 2023 Jun 18;80(7):182 |
1* | J:87368 Raetzman LT, Ross SA, Cook S, Dunwoodie SL, Camper SA, Thomas PQ, Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression. Dev Biol. 2004 Jan 15;265(2):329-40 |
1 | J:284150 Roberts RR, Bobzin L, Teng CS, Pal D, Tuzon CT, Schweitzer R, Merrill AE, FGF signaling patterns cell fate at the interface between tendon and bone. Development. 2019 Aug 2;146(15):dev170241 |
1 | J:180791 Saravanamuthu SS, Le TT, Gao CY, Cojocaru RI, Pandiyan P, Liu C, Zhang J, Zelenka PS, Brown NL, Conditional ablation of the Notch2 receptor in the ocular lens. Dev Biol. 2012 Feb 15;362(2):219-29 |
1 | J:213069 Vanorny DA, Prasasya RD, Chalpe AJ, Kilen SM, Mayo KE, Notch signaling regulates ovarian follicle formation and coordinates follicular growth. Mol Endocrinol. 2014 Apr;28(4):499-511 |
1* | J:132939 Varadkar P, Kraman M, Despres D, Ma G, Lozier J, McCright B, Notch2 is required for the proliferation of cardiac neural crest-derived smooth muscle cells. Dev Dyn. 2008 Apr;237(4):1144-52 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Notch3 notch 3 (Synonyms: hpbk, N3) | |
Results | Reference |
1 | J:310741 Briot A, Jaroszewicz A, Warren CM, Lu J, Touma M, Rudat C, Hofmann JJ, Airik R, Weinmaster G, Lyons K, Wang Y, Kispert A, Pellegrini M, Iruela-Arispe ML, Repression of Sox9 by Jag1 is continuously required to suppress the default chondrogenic fate of vascular smooth muscle cells. Dev Cell. 2014 Dec 22;31(6):707-21 |
2 | J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109 |
1 | J:173367 Ezratty EJ, Stokes N, Chai S, Shah AS, Williams SE, Fuchs E, A Role for the Primary Cilium in Notch Signaling and Epidermal Differentiation during Skin Development. Cell. 2011 Jun 24;145(7):1129-41 |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1 | J:63320 Favier B, Fliniaux I, Thelu J, Viallet JP, Demarchez M, Jahoda CA, Dhouailly D, Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators. Dev Dyn. 2000 Jul;218(3):426-37 |
1 | J:183603 Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A, Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res. 2011 Apr 1;108(7):813-23 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:64088 Ito T, Udaka N, Yazawa T, Okudela K, Hayashi H, Sudo T, Guillemot F, Kageyama R, Kitamura H, Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development. 2000 Sep;127(18):3913-21 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
2* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:277726 Lecland N, Hsu CY, Chemin C, Merdes A, Bierkamp C, Epidermal development requires ninein for spindle orientation and cortical microtubule organization. Life Sci Alliance. 2019 Apr;2(2) |
1 | J:171254 Matsumoto A, Onoyama I, Sunabori T, Kageyama R, Okano H, Nakayama KI, Fbxw7-dependent Degradation of Notch Is Required for Control of 'Stemness' and Neuronal-Glial Differentiation in Neural Stem Cells. J Biol Chem. 2011 Apr 15;286(15):13754-64 |
1 | J:214082 Maurer KA, Riesenberg AN, Brown NL, Notch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina. Development. 2014 Aug;141(16):3243-54 |
1 | J:51928 Mitsiadis TA, Hirsinger E, Lendahl U, Goridis C, Delta-notch signaling in odontogenesis: correlation with cytodifferentiation and evidence for feedback regulation. Dev Biol. 1998 Dec 15;204(2):420-31 |
1 | J:26831 Mitsiadis TA, Lardelli M, Lendahl U, Thesleff I, Expression of Notch 1, 2 and 3 is regulated by epithelial-mesenchymal interactions and retinoic acid in the developing mouse tooth and associated with determination of ameloblast cell fate. J Cell Biol. 1995 Jul;130(2):407-18 |
1 | J:238903 Mori M, Mahoney JE, Stupnikov MR, Paez-Cortez JR, Szymaniak AD, Varelas X, Herrick DB, Schwob J, Zhang H, Cardoso WV, Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors. Development. 2015 Jan 15;142(2):258-67 |
1 | J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77 |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
1 | J:299728 Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL, Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. Elife. 2019 Dec 4;8:e49977 |
1 | J:213069 Vanorny DA, Prasasya RD, Chalpe AJ, Kilen SM, Mayo KE, Notch signaling regulates ovarian follicle formation and coordinates follicular growth. Mol Endocrinol. 2014 Apr;28(4):499-511 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Notch4 notch 4 (Synonyms: Int-3, Int3, N4) | |
Results | Reference |
1 | J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109 |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1 | J:63320 Favier B, Fliniaux I, Thelu J, Viallet JP, Demarchez M, Jahoda CA, Dhouailly D, Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators. Dev Dyn. 2000 Jul;218(3):426-37 |
1 | J:183603 Grieskamp T, Rudat C, Ludtke TH, Norden J, Kispert A, Notch signaling regulates smooth muscle differentiation of epicardium-derived cells. Circ Res. 2011 Apr 1;108(7):813-23 |
1 | J:64088 Ito T, Udaka N, Yazawa T, Okudela K, Hayashi H, Sudo T, Guillemot F, Kageyama R, Kitamura H, Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium. Development. 2000 Sep;127(18):3913-21 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:213069 Vanorny DA, Prasasya RD, Chalpe AJ, Kilen SM, Mayo KE, Notch signaling regulates ovarian follicle formation and coordinates follicular growth. Mol Endocrinol. 2014 Apr;28(4):499-511 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Notum notum palmitoleoyl-protein carboxylesterase (Synonyms: 5730593N15Rik) | |
Results | Reference |
2 | J:350005 Adasooriya D, Jeong JK, Kyeong M, Kan S, Kim J, Cho ES, Cho SW, Notum regulates the cusp and root patterns in mouse molar. Sci Rep. 2024 Jun 13;14(1):13633 |
1* | J:329933 Akkuratova N, Faure L, Kameneva P, Kastriti ME, Adameyko I, Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics. Front Endocrinol (Lausanne). 2022;13:1020000 |
1 | J:279588 Canal F, Charawi S, Grimber G, Houbron C, Drouet V, Colnot S, Terris B, Cavard C, Perret C, Generation of Mice with Hepatocyte-Specific Conditional Deletion of Notum. PLoS One. 2016;11(3):e0150997 |
1* | J:260471 Gerhardt B, Leesman L, Burra K, Snowball J, Rosenzweig R, Guzman N, Ambalavanan M, Sinner D, Notum attenuates Wnt/beta-catenin signaling to promote tracheal cartilage patterning. Dev Biol. 2018 Apr 1;436(1):14-27 |
Nova1 NOVA alternative splicing regulator 1 (Synonyms: 9430099M15Rik, Nova-1) | |
Results | Reference |
1* | J:183118 Irimia M, Denuc A, Ferran JL, Pernaute B, Puelles L, Roy SW, Garcia-Fernandez J, Marfany G, Evolutionarily conserved A-to-I editing increases protein stability of the alternative splicing factor Nova1. RNA Biol. 2012 Jan 1;9(1):12-21 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Nova2 NOVA alternative splicing regulator 2 (Synonyms: LOC384569) | |
Results | Reference |
1 | J:234107 Saito Y, Miranda-Rottmann S, Ruggiu M, Park CY, Fak JJ, Zhong R, Duncan JS, Fabella BA, Junge HJ, Chen Z, Araya R, Fritzsch B, Hudspeth AJ, Darnell RB, NOVA2-mediated RNA regulation is required for axonal pathfinding during development. Elife. 2016;5:e14371 |
1 | J:163165 Yano M, Hayakawa-Yano Y, Mele A, Darnell RB, Nova2 regulates neuronal migration through an RNA switch in disabled-1 signaling. Neuron. 2010 Jun 24;66(6):848-58 |
Npas1 neuronal PAS domain protein 1 (Synonyms: bHLHe11, MOP5) | |
Results | Reference |
1* | J:134028 Levesque BM, Zhou S, Shan L, Johnston P, Kong Y, Degan S, Sunday ME, NPAS1 regulates branching morphogenesis in embryonic lung. Am J Respir Cell Mol Biol. 2007 Apr;36(4):427-34 |
1 | J:99833 Ohsawa S, Hamada S, Kakinuma Y, Yagi T, Miura M, Novel function of neuronal PAS domain protein 1 in erythropoietin expression in neuronal cells. J Neurosci Res. 2005 Feb 15;79(4):451-8 |
Npas3 neuronal PAS domain protein 3 (Synonyms: 4930423H22Rik, bHLHe12) | |
Results | Reference |
1* | J:58665 Brunskill EW, Witte DP, Shreiner AB, Potter SS, Characterization of npas3, a novel basic helix-loop-helix PAS gene expressed in the developing mouse nervous system. Mech Dev. 1999 Nov;88(2):237-41 |
1 | J:319920 Ypsilanti AR, Pattabiraman K, Catta-Preta R, Golonzhka O, Lindtner S, Tang K, Jones IR, Abnousi A, Juric I, Hu M, Shen Y, Dickel DE, Visel A, Pennachio LA, Hawrylycz M, Thompson CL, Zeng H, Barozzi I, Nord AS, Rubenstein JL, Transcriptional network orchestrating regional patterning of cortical progenitors. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2024795118 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
1 | J:150793 Zhou S, Degan S, Potts EN, Foster WM, Sunday ME, NPAS3 is a trachealess homolog critical for lung development and homeostasis. Proc Natl Acad Sci U S A. 2009 Jul 14;106(28):11691-6 |
Npas4 neuronal PAS domain protein 4 (Synonyms: LE-PAS, Npas4, Nxf) | |
Results | Reference |
1 | J:214381 Spiegel I, Mardinly AR, Gabel HW, Bazinet JE, Couch CH, Tzeng CP, Harmin DA, Greenberg ME, Npas4 regulates excitatory-inhibitory balance within neural circuits through cell-type-specific gene programs. Cell. 2014 May 22;157(5):1216-29 |
Npc2 NPC intracellular cholesterol transporter 2 (Synonyms: 2700012J19Rik, HE1) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Nphp3 nephronophthisis 3 (adolescent) (Synonyms: 3632410F03Rik, D330020E01Rik, nephrocystin 3, pcy) | |
Results | Reference |
1 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
1 | J:91453 Olbrich H, Fliegauf M, Hoefele J, Kispert A, Otto E, Volz A, Wolf MT, Sasmaz G, Trauer U, Reinhardt R, Sudbrak R, Antignac C, Gretz N, Walz G, Schermer B, Benzing T, Hildebrandt F, Omran H, Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis. Nat Genet. 2003 Aug;34(4):455-9 |
Nphs1 nephrosis 1, nephrin (Synonyms: nephrin) | |
Results | Reference |
1 | J:239479 Arora H, Boulberdaa M, Qureshi R, Bitirim V, Messadeq N, Dolle P, Nebigil CG, Prokineticin receptor 1 is required for mesenchymal-epithelial transition in kidney development. FASEB J. 2016 Aug;30(8):2733-40 |
1 | J:196018 Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W, Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell Rep. 2012 Jul 26;2(1):52-61 |
1 | J:189818 Haege S, Einer C, Thiele S, Mueller W, Nietzsche S, Lupp A, Mackay F, Schulz S, Stumm R, CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney. PLoS One. 2012;7(8):e42814 |
1 | J:140256 Hartleben B, Schweizer H, Lubben P, Bartram MP, Moller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB, Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. J Biol Chem. 2008 Aug 22;283(34):23033-8 |
1 | J:321428 Kruber P, Angay O, Winkler A, Bosl MR, Kneitz S, Heinze KG, Gessler M, Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation. Int J Cancer. 2019 Mar 15;144(6):1391-1400 |
1 | J:171288 Nishida K, Nakayama K, Yoshimura S, Murakami F, Role of Neph2 in pontine nuclei formation in the developing hindbrain. Mol Cell Neurosci. 2011 Mar;46(3):662-70 |
1* | J:113418 Ross MD, Martinka S, Mukherjee A, Sedor JR, Vinson C, Bruggeman LA, Math6 expression during kidney development and altered expression in a mouse model of glomerulosclerosis. Dev Dyn. 2006 Nov;235(11):3102-9 |
Nphs2 nephrosis 2, podocin (Synonyms: podocin) | |
Results | Reference |
1 | J:196018 Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W, Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell Rep. 2012 Jul 26;2(1):52-61 |
1 | J:189818 Haege S, Einer C, Thiele S, Mueller W, Nietzsche S, Lupp A, Mackay F, Schulz S, Stumm R, CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney. PLoS One. 2012;7(8):e42814 |
Npl N-acetylneuraminate pyruvate lyase (Synonyms: 0610033B02Rik) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Nploc4 NPL4 homolog, ubiquitin recognition factor (Synonyms: mKIAA1499) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
Npm1 nucleophosmin 1 (Synonyms: B23, NO38, nucleolar protein NO38) | |
Results | Reference |
1 | J:80512 Tsai RY, McKay RD, A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells. Genes Dev. 2002 Dec 1;16(23):2991-3003 |
Npnt nephronectin (Synonyms: 1110009H02Rik, POEM) | |
Results | Reference |
3 | J:170886 Fujiwara H, Ferreira M, Donati G, Marciano DK, Linton JM, Sato Y, Hartner A, Sekiguchi K, Reichardt LF, Watt FM, The basement membrane of hair follicle stem cells is a muscle cell niche. Cell. 2011 Feb 18;144(4):577-89 |
1 | J:321068 Maimets M, Pedersen MT, Guiu J, Dreier J, Thodberg M, Antoku Y, Schweiger PJ, Rib L, Bressan RB, Miao Y, Garcia KC, Sandelin A, Serup P, Jensen KB, Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling. Nat Commun. 2022 Feb 7;13(1):715 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
2* | J:72544 Morimura N, Tezuka Y, Watanabe N, Yasuda M, Miyatani S, Hozumi N, Tezuka Ki K, Molecular cloning of POEM: a novel adhesion molecule that interacts with alpha8beta1 integrin. J Biol Chem. 2001 Nov 9;276(45):42172-81 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1 | J:333737 Wilson CL, Hung CF, Burkel BM, Ponik SM, Gharib SA, Schnapp LM, Nephronectin is required to maintain right lung lobar separation during embryonic development. Am J Physiol Lung Cell Mol Physiol. 2023 Jan 31; |
Nppa natriuretic peptide type A (Synonyms: Anf, ANP, atrial natriuretic peptide, natriuretic peptide precursor A, Pnd) | |
Results | Reference |
1 | J:31876 Cameron VA, Aitken GD, Ellmers LJ, Kennedy MA, Espiner EA, The sites of gene expression of atrial, brain, and C-type natriuretic peptides in mouse fetal development: temporal changes in embryos and placenta. Endocrinology. 1996 Mar;137(3):817-24 |
1 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1 | J:355142 Gomez-Del Arco P, Isern J, Jimenez-Carretero D, Lopez-Maderuelo D, Pineiro-Sabaris R, El Abdellaoui-Soussi F, Torroja C, Vera-Pedrosa ML, Grima-Terren M, Benguria A, Simon-Chica A, Queiro-Palou A, Dopazo A, Sanchez-Cabo F, Jalife J, de la Pompa JL, Filgueiras-Rama D, Munoz-Canoves P, Redondo JM, The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development. Nat Commun. 2024 Oct 4;15(1):8602 |
1 | J:335098 Han F, Yang B, Chen Y, Liu L, Cheng X, Huang J, Zhou K, Zhang D, Xu E, Lai M, Lv B, Cheng H, Zhang H, Loss of GLTSCR1 causes congenital heart defects by regulating NPPA transcription. Angiogenesis. 2023 May;26(2):217-232 |
1 | J:192707 He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, Pu WT, Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res. 2012 Feb 3;110(3):406-15 |
1* | J:316724 Pedernera E, Gomora MJ, Meneses I, De Ita M, Mendez C, Androgen receptor is expressed in mouse cardiomyocytes at prenatal and early postnatal developmental stages. BMC Physiol. 2017 Aug 14;17(1):7 |
1 | J:338889 Siguero-Alvarez M, Salguero-Jimenez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sanchez-Saez F, Pineiro-Sabaris R, Felipe-Medina N, Torroja C, Gomez MJ, Sabater-Molina M, Escriba R, Richaud-Patin I, Iglesias-Garcia O, Sbroggio M, Callejas S, O'Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibanez B, Monserrat L, Perez-Pomares JM, Sanchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL, A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation. 2023 Jan 3;147(1):47-65 |
1 | J:46473 Ya J, Erdtsieck-Ernste EB, de Boer PA, van Kempen MJ, Jongsma H , Gros D , Moorman AF , Lamers WH, Heart defects in connexin43-deficient mice. Circ Res. 1998 Feb 23;82(3):360-6 |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
Nppb natriuretic peptide type B (Synonyms: BNP) | |
Results | Reference |
1 | J:31876 Cameron VA, Aitken GD, Ellmers LJ, Kennedy MA, Espiner EA, The sites of gene expression of atrial, brain, and C-type natriuretic peptides in mouse fetal development: temporal changes in embryos and placenta. Endocrinology. 1996 Mar;137(3):817-24 |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
Nppc natriuretic peptide type C (Synonyms: CNP, lbab, natriuretic peptide precursor C) | |
Results | Reference |
1 | J:31876 Cameron VA, Aitken GD, Ellmers LJ, Kennedy MA, Espiner EA, The sites of gene expression of atrial, brain, and C-type natriuretic peptides in mouse fetal development: temporal changes in embryos and placenta. Endocrinology. 1996 Mar;137(3):817-24 |
Npr2 natriuretic peptide receptor 2 (Synonyms: cn, guanylyl cyclase-B, pwe) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Npr3 natriuretic peptide receptor 3 (Synonyms: B430320C24Rik, lgj, longjohn, Nppc receptor, NPR-C) | |
Results | Reference |
1 | J:317975 Lu P, Wang Y, Liu Y, Wang Y, Wu B, Zheng D, Harvey RP, Zhou B, Perinatal angiogenesis from pre-existing coronary vessels via DLL4-NOTCH1 signalling. Nat Cell Biol. 2021 Sep;23(9):967-977 |
1 | J:335167 Lu P, Wu B, Wang Y, Russell M, Liu Y, Bernard DJ, Zheng D, Zhou B, Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis. Dev Cell. 2023 Mar 29; |
Nptx1 neuronal pentraxin 1 (Synonyms: D11Bwg1004e, Np1) | |
Results | Reference |
1 | J:226941 Akerberg BN, Sarangam ML, Stankunas K, Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Dev Biol. 2015 Nov 1;407(1):158-72 |
Npy neuropeptide Y (Synonyms: 0710005A05Rik) | |
Results | Reference |
1 | J:328140 Asgarian Z, Oliveira MG, Stryjewska A, Maragkos I, Rubin AN, Magno L, Pachnis V, Ghorbani M, Hiebert SW, Denaxa M, Kessaris N, MTG8 interacts with LHX6 to specify cortical interneuron subtype identity. Nat Commun. 2022 Sep 5;13(1):5217 |
1* | J:199435 Barraud P, St John JA, Stolt CC, Wegner M, Baker CV, Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Biol Open. 2013 Jul 15;2(7):750-9 |
1* | J:308824 de Guia RM, Hassing AS, Ma T, Plucinska K, Holst B, Gerhart-Hines Z, Emanuelli B, Treebak JT, Ablation of Nampt in AgRP neurons leads to neurodegeneration and impairs fasting- and ghrelin-mediated food intake. FASEB J. 2021 May;35(5):e21450 |
1* | J:74080 Del Rio JA, Martinez A, Auladell C, Soriano E, Developmental history of the subplate and developing white matter in the murine neocortex. Neuronal organization and relationship with the main afferent systems at embryonic and perinatal stages. Cereb Cortex. 2000 Aug;10(8):784-801 |
1 | J:188332 Delogu A, Sellers K, Zagoraiou L, Bocianowska-Zbrog A, Mandal S, Guimera J, Rubenstein JL, Sugden D, Jessell T, Lumsden A, Subcortical visual shell nuclei targeted by ipRGCs develop from a Sox14+-GABAergic progenitor and require Sox14 to regulate daily activity rhythms. Neuron. 2012 Aug 23;75(4):648-62 |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:163224 Garcia-Lopez M, Abellan A, Legaz I, Rubenstein JL, Puelles L, Medina L, Histogenetic compartments of the mouse centromedial and extended amygdala based on gene expression patterns during development. J Comp Neurol. 2008 Jan 1;506(1):46-74 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1 | J:142008 Huang M, Huang T, Xiang Y, Xie Z, Chen Y, Yan R, Xu J, Cheng L, Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons. Dev Biol. 2008 Jul 2;322(2):394-405 |
1 | J:35196 Jackerott M, Oster A, Larsson LI, PYY in developing murine islet cells: comparisons to development of islet hormones, NPY, and BrdU incorporation. J Histochem Cytochem. 1996 Aug;44(8):809-17 |
1 | J:170540 Jeong Y, Dolson DK, Waclaw RR, Matise MP, Sussel L, Campbell K, Kaestner KH, Epstein DJ, Spatial and temporal requirements for sonic hedgehog in the regulation of thalamic interneuron identity. Development. 2011 Feb;138(3):531-41 |
1 | J:263715 Lee B, Kim J, An T, Kim S, Patel EM, Raber J, Lee SK, Lee S, Lee JW, Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons. Nat Commun. 2018 May 23;9(1):2026 |
2 | J:244498 Lee B, Lee M, Song S, Loi LD, Lam DT, Yoon J, Baek K, Curtis DJ, Jeong Y, Specification of neurotransmitter identity by Tal1 in thalamic nuclei. Dev Dyn. 2017 Oct;246(10):749-758 |
1 | J:237344 Lee B, Lee S, Lee SK, Lee JW, The LIM-homeobox transcription factor Isl1 plays crucial roles in the development of multiple arcuate nucleus neurons. Development. 2016 Oct 15;143(20):3763-3773 |
1 | J:344891 Maunsell HR, Ellis K, Kelley MW, Driver EC, Lrrn1 Regulates Medial Boundary Formation in the Developing Mouse Organ of Corti. J Neurosci. 2023 Jul 19;43(29):5305-5318 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1* | J:146286 Real MA, Heredia R, Labrador Mdel C, Davila JC, Guirado S, Expression of somatostatin and neuropeptide Y in the embryonic, postnatal, and adult mouse amygdalar complex. J Comp Neurol. 2009 Apr 1;513(4):335-48 |
1* | J:268254 Rich CA, Perera SN, Andratschke J, Stolt CC, Buehler DP, Southard-Smith EM, Wegner M, Britsch S, Baker CVH, Olfactory ensheathing cells abutting the embryonic olfactory bulb express Frzb, whose deletion disrupts olfactory axon targeting. Glia. 2018 Dec;66(12):2617-2631 |
1 | J:142359 Seah C, Levy MA, Jiang Y, Mokhtarzada S, Higgs DR, Gibbons RJ, Berube NG, Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53. J Neurosci. 2008 Nov 19;28(47):12570-80 |
1 | J:197638 van den Berghe V, Stappers E, Vandesande B, Dimidschstein J, Kroes R, Francis A, Conidi A, Lesage F, Dries R, Cazzola S, Berx G, Kessaris N, Vanderhaeghen P, van Ijcken W, Grosveld FG, Goossens S, Haigh JJ, Fishell G, Goffinet A, Aerts S, Huylebroeck D, Seuntjens E, Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1. Neuron. 2013 Jan 9;77(1):70-82 |
1 | J:132518 Vue TY, Aaker J, Taniguchi A, Kazemzadeh C, Skidmore JM, Martin DM, Martin JF, Treier M, Nakagawa Y, Characterization of progenitor domains in the developing mouse thalamus. J Comp Neurol. 2007 Nov 1;505(1):73-91 |
Npy1r neuropeptide Y receptor Y1 (Synonyms: Npyr, Y1-R) | |
Results | Reference |
1 | J:119559 Bouwman J, Spijker S, Schut D, Wachtler B, Ylstra B, Smit AB, Verhage M, Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse. J Neurochem. 2006 Oct;99(1):84-96 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Npy2r neuropeptide Y receptor Y2 (Synonyms: NPY-Y2 receptor) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Nqo1 NAD(P)H dehydrogenase, quinone 1 (Synonyms: Dia4, NAD(P)H dehydrogenase (quinone), NMO1, Nmor1, NQO1, Ox-1, Ox1, QR1) | |
Results | Reference |
1* | J:191045 Huebner AJ, Dai D, Morasso M, Schmidt EE, Schafer M, Werner S, Roop DR, Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero. Dev Cell. 2012 Dec 11;23(6):1238-46 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Nr0b1 nuclear receptor subfamily 0, group B, member 1 (Synonyms: Ahc, Ahch, AHX, Dax1, DAX-1) | |
Results | Reference |
1* | J:35232 Bae DS, Schaefer ML, Partan BW, Muglia L, Characterization of the mouse DAX-1 gene reveals evolutionary conservation of a unique amino-terminal motif and widespread expression in mouse tissue. Endocrinology. 1996 Sep;137(9):3921-7 |
1 | J:108374 Vesper AH, Raetzman LT, Camper SA, Role of prophet of Pit1 (PROP1) in gonadotrope differentiation and puberty. Endocrinology. 2006 Apr;147(4):1654-63 |
Nr0b2 nuclear receptor subfamily 0, group B, member 2 (Synonyms: SHP, SHP-1, small heterodimer partner) | |
Results | Reference |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
Nr1d1 nuclear receptor subfamily 1, group D, member 1 (Synonyms: A530070C09Rik, rev-erbA(alpha), REV-ERBalpha) | |
Results | Reference |
1* | J:171710 Mollema NJ, Yuan Y, Jelcick AS, Sachs AJ, von Alpen D, Schorderet D, Escher P, Haider NB, Nuclear receptor Rev-erb alpha (Nr1d1) functions in concert with Nr2e3 to regulate transcriptional networks in the retina. PLoS One. 2011;6(3):e17494 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Nr1d2 nuclear receptor subfamily 1, group D, member 2 (Synonyms: Rev-erb beta, RVR) | |
Results | Reference |
1* | J:20436 Retnakaran R, Flock G, Giguere V, Identification of RVR, a novel orphan nuclear receptor that acts as a negative transcriptional regulator. Mol Endocrinol. 1994 Sep;8(9):1234-44 |
Nr1h2 nuclear receptor subfamily 1, group H, member 2 (Synonyms: LXRB, LXRbeta, RIP15, Unr2) | |
Results | Reference |
1 | J:91311 Annicotte JS, Schoonjans K, Auwerx J, Expression of the liver X receptor alpha and beta in embryonic and adult mice. Anat Rec A Discov Mol Cell Evol Biol. 2004 Apr;277(2):312-6 |
1 | J:261286 Cai Y, Tang X, Chen X, Li X, Wang Y, Bao X, Wang L, Sun D, Zhao J, Xing Y, Warner M, Xu H, Gustafsson JA, Fan X, Liver X receptor beta regulates the development of the dentate gyrus and autistic-like behavior in the mouse. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2725-E2733 |
1 | J:139119 Fan X, Kim HJ, Bouton D, Warner M, Gustafsson JA, Expression of liver X receptor beta is essential for formation of superficial cortical layers and migration of later-born neurons. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13445-50 |
Nr1h3 nuclear receptor subfamily 1, group H, member 3 (Synonyms: LXR alpha, Unr1) | |
Results | Reference |
1 | J:91311 Annicotte JS, Schoonjans K, Auwerx J, Expression of the liver X receptor alpha and beta in embryonic and adult mice. Anat Rec A Discov Mol Cell Evol Biol. 2004 Apr;277(2):312-6 |
Nr1h4 nuclear receptor subfamily 1, group H, member 4 (Synonyms: Fxr, FXR, HRR1, RIP14, Rxrip14) | |
Results | Reference |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1 | J:111670 Kyrmizi I, Hatzis P, Katrakili N, Tronche F, Gonzalez FJ, Talianidis I, Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev. 2006 Aug 15;20(16):2293-305 |
Nr1i2 nuclear receptor subfamily 1, group I, member 2 (Synonyms: mPXR, Pregnane X receptor, PXR, PXR.1, PXR.2, SXR) | |
Results | Reference |
1* | J:317552 Casey SC, Blumberg B, The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver. Mol Endocrinol. 2012 Jun;26(6):916-25 |
1 | J:111670 Kyrmizi I, Hatzis P, Katrakili N, Tronche F, Gonzalez FJ, Talianidis I, Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev. 2006 Aug 15;20(16):2293-305 |
1 | J:325181 Saeki N, Itoh Y, Kanai R, Itoh S, Inububishi T, Akiyama S, Inui-Yamamoto C, Abe M, Pregnane X receptor (PXR) represses osteoblast differentiation through repression of the Hedgehog signaling pathway. Exp Cell Res. 2022 Jul 1;416(1):113156 |
1 | J:269997 Takeuchi Y, Kito A, Itoh S, Naruse H, Fujikawa J, Sadek KM, Akiyama S, Yamashiro T, Wakisaka S, Abe M, Kruppel-Like Factor 4 represses osteoblast differentiation via ciliary Hedgehog signaling. Exp Cell Res. 2018 Oct 15;371(2):417-425 |
Nr2c1 nuclear receptor subfamily 2, group C, member 1 (Synonyms: 4831444H07Rik, Eenr, TR2, Tr2-11) | |
Results | Reference |
1* | J:229480 Baker JL, Wood B, Karpinski BA, LaMantia AS, Maynard TM, Testicular receptor 2, Nr2c1, is associated with stem cells in the developing olfactory epithelium and other cranial sensory and skeletal structures. Gene Expr Patterns. 2016 Jan;20(1):71-9 |
1* | J:32735 Lee HJ, Young WJ, Shih CY, Chang C, Suppression of the human erythropoietin gene expression by the TR2 orphan receptor, a member of the steroid receptor superfamily. J Biol Chem. 1996 Apr 26;271(17):10405-12 |
1* | J:30130 Lin TM, Young WJ, Chang C, Multiple functions of the TR2-11 orphan receptor in modulating activation of two key cis-acting elements involved in the retinoic acid signal transduction system. J Biol Chem. 1995 Dec 15;270(50):30121-8 |
1 | J:248772 Olivares AM, Han Y, Soto D, Flattery K, Marini J, Mollema N, Haider A, Escher P, DeAngelis MM, Haider NB, The nuclear hormone receptor gene Nr2c1 (Tr2) is a critical regulator of early retina cell patterning. Dev Biol. 2017 Sep 1;429(1):343-355 |
Nr2e1 nuclear receptor subfamily 2, group E, member 1 (Synonyms: Mtll, Nr2e1, tailless, Tlx) | |
Results | Reference |
1* | J:127237 Belz T, Liu HK, Bock D, Takacs A, Vogt M, Wintermantel T, Brandwein C, Gass P, Greiner E, Schutz G, Inactivation of the gene for the nuclear receptor tailless in the brain preserving its function in the eye. Eur J Neurosci. 2007 Oct;26(8):2222-7 |
1* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
1 | J:81762 Stenman J, Yu RT, Evans RM, Campbell K, Tlx and Pax6 co-operate genetically to establish the pallio-subpallial boundary in the embryonic mouse telencephalon. Development. 2003 Mar;130(6):1113-22 |
Nr2e3 nuclear receptor subfamily 2, group E, member 3 (Synonyms: photoreceptor-specific nuclear receptor, Pnr, RNR) | |
Results | Reference |
1 | J:91665 Cheng H, Khanna H, Oh EC, Hicks D, Mitton KP, Swaroop A, Photoreceptor-specific nuclear receptor NR2E3 functions as a transcriptional activator in rod photoreceptors. Hum Mol Genet. 2004 Aug 1;13(15):1563-75 |
1 | J:285747 Liu S, Liu X, Li S, Huang X, Qian H, Jin K, Xiang M, Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5016-5027 |
1* | J:171710 Mollema NJ, Yuan Y, Jelcick AS, Sachs AJ, von Alpen D, Schorderet D, Escher P, Haider NB, Nuclear receptor Rev-erb alpha (Nr1d1) functions in concert with Nr2e3 to regulate transcriptional networks in the retina. PLoS One. 2011;6(3):e17494 |
1 | J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77 |
Nr2f1 nuclear receptor subfamily 2, group F, member 1 (Synonyms: COUP-TF1, COUP-TFI, Erbal3, Tcfcoup1) | |
Results | Reference |
1* | J:184357 Dye CA, El Shawa H, Huffman KJ, A lifespan analysis of intraneocortical connections and gene expression in the mouse I. Cereb Cortex. 2011 Jun;21(6):1311-30 |
1* | J:79830 Garel S, Yun K, Grosschedl R, Rubenstein JL, The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development. 2002 Dec;129(24):5621-34 |
1* | J:141042 Naka H, Nakamura S, Shimazaki T, Okano H, Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development. Nat Neurosci. 2008 Sep;11(9):1014-23 |
1 | J:241853 Parisot J, Flore G, Bertacchi M, Studer M, COUP-TFI mitotically regulates production and migration of dentate granule cells and modulates hippocampal Cxcr4 expression. Development. 2017 Jun 01;144(11):2045-2058 |
1* | J:18563 Qiu Y, Cooney AJ, Kuratani S, DeMayo FJ, Tsai SY, Tsai MJ, Spatiotemporal expression patterns of chicken ovalbumin upstream promoter-transcription factors in the developing mouse central nervous system: evidence for a role in segmental patterning of the diencephalon. Proc Natl Acad Sci U S A. 1994 May 10;91(10):4451-5 |
1* | J:40975 Sack MN, Disch DL, Rockman HA, Kelly DP, A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6438-43 |
2* | J:264553 Tarchini B, Longo-Guess C, Tian C, Tadenev ALD, Devanney N, Johnson KR, A spontaneous mouse deletion in Mctp1 uncovers a long-range cis-regulatory region crucial for NR2F1 function during inner ear development. Dev Biol. 2018 Nov 15;443(2):153-164 |
1 | J:342641 Tenney AP, Di Gioia SA, Webb BD, Chan WM, de Boer E, Garnai SJ, Barry BJ, Ray T, Kosicki M, Robson CD, Zhang Z, Collins TE, Gelber A, Pratt BM, Fujiwara Y, Varshney A, Lek M, Warburton PE, Van Ryzin C, Lehky TJ, Zalewski C, King KA, Brewer CC, Thurm A, Snow J, Facio FM, Narisu N, Bonnycastle LL, Swift A, Chines PS, Bell JL, Mohan S, Whitman MC, Staffieri SE, Elder JE, Demer JL, Torres A, Rachid E, Al-Haddad C, Boustany RM, Mackey DA, Brady AF, Fenollar-Cortes M, Fradin M, Kleefstra T, Padberg GW, Raskin S, Sato MT, Orkin SH, Parker SCJ, Hadlock TA, Vissers LELM, van Bokhoven H, Jabs EW, Collins FS, Pennacchio LA, Manoli I, Engle EC, Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis. Nat Genet. 2023 Jul;55(7):1149-1163 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Nr2f2 nuclear receptor subfamily 2, group F, member 2 (Synonyms: 9430015G03Rik, Aporp1, ARP-1, COUP-TF2, COUP-TFII, EAR3, Tcfcoup2) | |
Results | Reference |
1 | J:350469 Alderman PJ, Saxon D, Torrijos-Saiz LI, Sharief M, Page CE, Baroudi JK, Biagiotti SW, Butyrkin VA, Melamed A, Kuo CT, Vicini S, Garcia-Verdugo JM, Herranz-Perez V, Corbin JG, Sorrells SF, Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala. Neuron. 2024 Feb 21;112(4):574-592.e10 |
1 | J:359451 Amato CM, Xu X, Yao HH, An extragenital cell population contributes to urethra closure during mouse penis development. Sci Adv. 2024 Dec 6;10(49):eadp0673 |
1 | J:307093 Amato CM, Yao HH, Developmental and sexual dimorphic atlas of the prenatal mouse external genitalia at the single-cell level. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2103856118 |
1* | J:193583 Cai Y, Zhang Q, Wang C, Zhang Y, Ma T, Zhou X, Tian M, Rubenstein JL, Yang Z, Nuclear receptor COUP-TFII-expressing neocortical interneurons are derived from the medial and lateral/caudal ganglionic eminence and define specific subsets of mature interneurons. J Comp Neurol. 2013 Feb 1;521(2):479-97 |
2 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
2 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1 | J:111670 Kyrmizi I, Hatzis P, Katrakili N, Tronche F, Gonzalez FJ, Talianidis I, Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev. 2006 Aug 15;20(16):2293-305 |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
1* | J:62941 Malpel S, Mendelsohn C, Cardoso WV, Regulation of retinoic acid signaling during lung morphogenesis. Development. 2000 Jul;127(14):3057-67 |
1 | J:262023 Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K, Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling. Circ Res. 2017 Apr 14;120(8):1276-1288 |
1* | J:141042 Naka H, Nakamura S, Shimazaki T, Okano H, Requirement for COUP-TFI and II in the temporal specification of neural stem cells in CNS development. Nat Neurosci. 2008 Sep;11(9):1014-23 |
1* | J:326026 Prokopuk L, Jarred EG, Blucher RO, McLaughlin EA, Stringer JM, Western PS, An essential role for Polycomb Repressive Complex 2 in the mouse ovary. Reproduction. 2022 Feb 17;163(3):167-182 |
1* | J:18563 Qiu Y, Cooney AJ, Kuratani S, DeMayo FJ, Tsai SY, Tsai MJ, Spatiotemporal expression patterns of chicken ovalbumin upstream promoter-transcription factors in the developing mouse central nervous system: evidence for a role in segmental patterning of the diencephalon. Proc Natl Acad Sci U S A. 1994 May 10;91(10):4451-5 |
1 | J:216158 Rastetter RH, Bernard P, Palmer JS, Chassot AA, Chen H, Western PS, Ramsay RG, Chaboissier MC, Wilhelm D, Marker genes identify three somatic cell types in the fetal mouse ovary. Dev Biol. 2014 Oct 15;394(2):242-52 |
1* | J:40975 Sack MN, Disch DL, Rockman HA, Kelly DP, A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6438-43 |
1 | J:158959 Srinivasan RS, Geng X, Yang Y, Wang Y, Mukatira S, Studer M, Porto MP, Lagutin O, Oliver G, The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells. Genes Dev. 2010 Apr 1;24(7):696-707 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
Nr3c1 nuclear receptor subfamily 3, group C, member 1 (Synonyms: glucocorticoid receptor, GR, Grl-1, Grl1) | |
Results | Reference |
2 | J:321162 Boix J, Carceller E, Sevilla LM, Marcos-Garces V, Perez P, The mineralocorticoid receptor plays a transient role in mouse skin development. Exp Dermatol. 2016 Jan;25(1):69-71 |
1 | J:361267 Cincotta SA, Richardson N, Foecke MH, Laird DJ, Differential susceptibility of male and female germ cells to glucocorticoid-mediated signaling. Elife. 2024 Jan 16;12 |
1* | J:22585 Jaskoll T, Choy HA, Melnick M, Glucocorticoids, TGF-beta, and embryonic mouse salivary gland morphogenesis. J Craniofac Genet Dev Biol. 1994 Oct-Dec;14(4):217-30 |
1* | J:33469 Jaskoll T, Choy HA, Melnick M, The glucocorticoid-glucocorticoid receptor signal transduction pathway, transforming growth factor-beta, and embryonic mouse lung development in vivo. Pediatr Res. 1996 May;39(5):749-59 |
1 | J:237343 Laresgoiti U, Nikolic MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL, Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016 Oct 15;143(20):3686-3699 |
2* | J:28514 Lau EC, Li ZQ, Santos V, Slavkin HC, Messenger RNA phenotyping for semi-quantitative comparison of glucocorticoid receptor transcript levels in the developing embryonic mouse palate. J Steroid Biochem Mol Biol. 1993 Dec;46(6):751-8 |
1 | J:263715 Lee B, Kim J, An T, Kim S, Patel EM, Raber J, Lee SK, Lee S, Lee JW, Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons. Nat Commun. 2018 May 23;9(1):2026 |
1 | J:200617 Li A, Hardy R, Stoner S, Tuckermann J, Seibel M, Zhou H, Deletion of mesenchymal glucocorticoid receptor attenuates embryonic lung development and abdominal wall closure. PLoS One. 2013;8(5):e63578 |
1 | J:199136 Rog-Zielinska EA, Thomson A, Kenyon CJ, Brownstein DG, Moran CM, Szumska D, Michailidou Z, Richardson J, Owen E, Watt A, Morrison H, Forrester LM, Bhattacharya S, Holmes MC, Chapman KE, Glucocorticoid receptor is required for foetal heart maturation. Hum Mol Genet. 2013 Aug 15;22(16):3269-82 |
1 | J:182938 Sevilla LM, Bayo P, Latorre V, Sanchis A, Perez P, Glucocorticoid receptor regulates overlapping and differential gene subsets in developing and adult skin. Mol Endocrinol. 2010 Nov;24(11):2166-78 |
2* | J:168512 Simard M, Cote M, Provost PR, Tremblay Y, Expression of genes related to the hypothalamic-pituitary-adrenal axis in murine fetal lungs in late gestation. Reprod Biol Endocrinol. 2010;8:134 |
1 | J:89625 Speirs HJ, Seckl JR, Brown RW, Ontogeny of glucocorticoid receptor and 11beta-hydroxysteroid dehydrogenase type-1 gene expression identifies potential critical periods of glucocorticoid susceptibility during development. J Endocrinol. 2004 Apr;181(1):105-16 |
1 | J:80418 Thompson A, Han VK, Yang K, Spatial and temporal patterns of expression of 11beta-hydroxysteroid dehydrogenase types 1 and 2 messenger RNA and glucocorticoid receptor protein in the murine placenta and uterus during late pregnancy. Biol Reprod. 2002 Dec;67(6):1708-18 |
1 | J:90284 Thompson A, Han VK, Yang K, Differential expression of 11beta-hydroxysteroid dehydrogenase types 1 and 2 mRNA and glucocorticoid receptor protein during mouse embryonic development. J Steroid Biochem Mol Biol. 2004 Apr;88(4-5):367-75 |
Nr3c2 nuclear receptor subfamily 3, group C, member 2 (Synonyms: aldosterone receptor, mineralocorticoid receptor, Mlr, MR) | |
Results | Reference |
1 | J:74133 Kretz O, Schmid W, Berger S, Gass P, The mineralocorticoid receptor expression in the mouse CNS is conserved during development. Neuroreport. 2001 May 8;12(6):1133-7 |
Nr4a2 nuclear receptor subfamily 4, group A, member 2 (Synonyms: HZF-3, Nurr1, RNR-1) | |
Results | Reference |
1 | J:250440 Ferguson R, Serafeimidou-Pouliou E, Subramanian V, Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation. J Anat. 2016 Dec;229(6):871-891 |
1 | J:208050 Huang TN, Chuang HC, Chou WH, Chen CY, Wang HF, Chou SJ, Hsueh YP, Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality. Nat Neurosci. 2014 Feb;17(2):240-7 |
1 | J:151918 Jiang H, Xiang M, Subtype specification of GABAergic amacrine cells by the orphan nuclear receptor Nr4a2/Nurr1. J Neurosci. 2009 Aug 19;29(33):10449-59 |
1* | J:136893 Lavoie PL, Budry L, Balsalobre A, Drouin J, Developmental Dependence on NurRE and EboxNeuro for Expression of Pituitary Proopiomelanocortin. Mol Endocrinol. 2008 Jul;22(7):1647-57 |
1 | J:308430 Lopez-Gonzalez L, Alonso A, Garcia-Calero E, de Puelles E, Puelles L, Tangential Intrahypothalamic Migration of the Mouse Ventral Premamillary Nucleus and Fgf8 Signaling. Front Cell Dev Biol. 2021;9:676121 |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
1 | J:335191 Munz M, Bharioke A, Kosche G, Moreno-Juan V, Brignall A, Rodrigues TM, Graff-Meyer A, Ulmer T, Haeuselmann S, Pavlinic D, Ledergerber N, Gross-Scherf B, Rozsa B, Krol J, Picelli S, Cowan CS, Roska B, Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex. Cell. 2023 Apr 27;186(9):1930-1949.e31 |
2 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1 | J:192558 Rabe TI, Griesel G, Blanke S, Kispert A, Leitges M, van der Zwaag B, Burbach JP, Varoqueaux F, Mansouri A, The transcription factor Uncx4.1 acts in a short window of midbrain dopaminergic neuron differentiation. Neural Dev. 2012;7:39 |
1 | J:287604 Ratie L, Desmaris E, Garcia-Moreno F, Hoerder-Suabedissen A, Kelman A, Theil T, Bellefroid EJ, Molnar Z, Loss of Dmrt5 Affects the Formation of the Subplate and Early Corticogenesis. Cereb Cortex. 2020 May 14;30(5):3296-3312 |
1 | J:234107 Saito Y, Miranda-Rottmann S, Ruggiu M, Park CY, Fak JJ, Zhong R, Duncan JS, Fabella BA, Junge HJ, Chen Z, Araya R, Fritzsch B, Hudspeth AJ, Darnell RB, NOVA2-mediated RNA regulation is required for axonal pathfinding during development. Elife. 2016;5:e14371 |
1 | J:160292 Shimizu T, Nakazawa M, Kani S, Bae YK, Shimizu T, Kageyama R, Hibi M, Zinc finger genes Fezf1 and Fezf2 control neuronal differentiation by repressing Hes5 expression in the forebrain. Development. 2010 Jun;137(11):1875-85 |
1 | J:73864 Wallen A A, Castro DS, Zetterstrom RH, Karlen M, Olson L, Ericson J, Perlmann T, Orphan nuclear receptor Nurr1 is essential for Ret expression in midbrain dopamine neurons and in the brain stem. Mol Cell Neurosci. 2001 Dec;18(6):649-63 |
1 | J:161774 Wang S, Turner EE, Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity. J Neurosci. 2010 Jul 7;30(27):9224-7 |
1 | J:354849 Wutikeli H, Yu Y, Zhang T, Cao J, Nawy S, Shen Y, Role of Elavl-like RNA-binding protein in retinal development and signal transduction. Biochim Biophys Acta Mol Basis Dis. 2024 Sep 20;1871(1):167518 |
1 | J:319920 Ypsilanti AR, Pattabiraman K, Catta-Preta R, Golonzhka O, Lindtner S, Tang K, Jones IR, Abnousi A, Juric I, Hu M, Shen Y, Dickel DE, Visel A, Pennachio LA, Hawrylycz M, Thompson CL, Zeng H, Barozzi I, Nord AS, Rubenstein JL, Transcriptional network orchestrating regional patterning of cortical progenitors. Proc Natl Acad Sci U S A. 2021 Dec 21;118(51):e2024795118 |
Nr4a3 nuclear receptor subfamily 4, group A, member 3 (Synonyms: MINOR, Nor1, NOR-1, TEC) | |
Results | Reference |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
Nr5a1 nuclear receptor subfamily 5, group A, member 1 (Synonyms: Ad4BP, adrenal 4-binding protein, ELP, Ftzf1, Ftz-F1, SF-1, SF1, steroidogenic factor 1) | |
Results | Reference |
1 | J:309359 Brinkmeier ML, Bando H, Camarano AC, Fujio S, Yoshimoto K, de Souza FS, Camper SA, Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. J Clin Invest. 2020 Aug 3;130(8):4501-4515 |
1 | J:57052 Cao G, Zhao L, Stangl H, Hasegawa T, Richardson JA, Parker KL, Hobbs HH, Developmental and hormonal regulation of murine scavenger receptor, class B, type 1. Mol Endocrinol. 1999 Sep;13(9):1460-73 |
1 | J:233385 Castinetti F, Brinkmeier ML, Mortensen AH, Vella KR, Gergics P, Brue T, Hollenberg AN, Gan L, Camper SA, ISL1 Is Necessary for Maximal Thyrotrope Response to Hypothyroidism. Mol Endocrinol. 2015 Oct;29(10):1510-21 |
1* | J:60198 Emmen JM, McLuskey A, Adham IM, Engel W, Verhoef-Post M, Themmen AP, Grootegoed JA, Brinkmann AO, Involvement of insulin-like factor 3 (Insl3) in diethylstilbestrol-induced cryptorchidism. Endocrinology. 2000 Feb;141(2):846-9 |
2 | J:315113 Hafner R, Bohnenpoll T, Rudat C, Schultheiss TM, Kispert A, Fgfr2 is required for the expansion of the early adrenocortical primordium. Mol Cell Endocrinol. 2015 Sep 15;413:168-77 |
1 | J:168522 Huang CC, Miyagawa S, Matsumaru D, Parker KL, Yao HH, Progenitor cell expansion and organ size of mouse adrenal is regulated by sonic hedgehog. Endocrinology. 2010 Mar;151(3):1119-28 |
1* | J:163555 Huang CC, Yao HH, Inactivation of Dicer1 in Steroidogenic factor 1-positive cells reveals tissue-specific requirement for Dicer1 in adrenal, testis, and ovary. BMC Dev Biol. 2010;10:66 |
1* | J:96531 Huber K, Karch N, Ernsberger U, Goridis C, Unsicker K, The role of Phox2B in chromaffin cell development. Dev Biol. 2005 Mar 15;279(2):501-8 |
1* | J:42236 Ikeda Y, Shen WH, Ingraham HA, Parker KL, Developmental expression of mouse steroidogenic factor-1, an essential regulator of the steroid hydroxylases. Mol Endocrinol. 1994 May;8(5):654-62 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
3* | J:118493 Katoh-Fukui Y, Owaki A, Toyama Y, Kusaka M, Shinohara Y, Maekawa M, Toshimori K, Morohashi K, Mouse Polycomb M33 is required for splenic vascular and adrenal gland formation through regulating Ad4BP/SF1 expression. Blood. 2005 Sep 1;106(5):1612-20 |
1 | J:138575 Kim AC, Reuter AL, Zubair M, Else T, Serecky K, Bingham NC, Lavery GG, Parker KL, Hammer GD, Targeted disruption of beta-catenin in Sf1-expressing cells impairs development and maintenance of the adrenal cortex. Development. 2008 Aug;135(15):2593-602 |
2 | J:155826 King P, Paul A, Laufer E, Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21185-90 |
1 | J:307764 Kothandapani A, Larsen MC, Lee J, Jorgensen JS, Jefcoate CR, Distinctive functioning of STARD1 in the fetal Leydig cells compared to adult Leydig and adrenal cells. Impact of Hedgehog signaling via the primary cilium. Mol Cell Endocrinol. 2021 Jul 1;531:111265 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1* | J:231259 Krill KT, Gurdziel K, Heaton JH, Simon DP, Hammer GD, Dicer deficiency reveals microRNAs predicted to control gene expression in the developing adrenal cortex. Mol Endocrinol. 2013 May;27(5):754-68 |
1 | J:89087 Lamolet B, Poulin G, Chu K, Guillemot F, Tsai MJ, Drouin J, Tpit-independent function of NeuroD1(BETA2) in pituitary corticotroph differentiation. Mol Endocrinol. 2004 Apr;18(4):995-1003 |
3 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
1 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1* | J:53330 Morohashi K, Tsuboi-Asai H, Matsushita S, Suda M, Nakashima M, Sasano H, Hataba Y, Li CL, Fukata J, Irie J, Watanabe T, Nagura H, Li E, Structural and functional abnormalities in the spleen of an mFtz-F1 gene-disrupted mouse. Blood. 1999 Mar 1;93(5):1586-94 |
1 | J:179464 Paul A, Laufer E, Endogenous biotin as a marker of adrenocortical cells with steroidogenic potential. Mol Cell Endocrinol. 2011 Apr 10;336(1-2):133-40 |
1 | J:197599 Pitetti JL, Calvel P, Romero Y, Conne B, Truong V, Papaioannou MD, Schaad O, Docquier M, Herrera PL, Wilhelm D, Nef S, Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice. PLoS Genet. 2013;9(1):e1003160 |
1* | J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20 |
1 | J:82562 Pulichino AM, Vallette-Kasic S, Tsai JP, Couture C, Gauthier Y, Drouin J, Tpit determines alternate fates during pituitary cell differentiation. Genes Dev. 2003 Mar 15;17(6):738-47 |
1 | J:308864 Rotgers E, Nicol B, Rodriguez K, Rattan S, Flaws JA, Yao HH, Constitutive expression of Steroidogenic factor-1 (NR5A1) disrupts ovarian functions, fertility, and metabolic homeostasis in female mice. FASEB J. 2021 Aug;35(8):e21770 |
1 | J:325352 Sahut-Barnola I, Lefrancois-Martinez AM, Dufour D, Botto JM, Kamilaris C, Faucz FR, Stratakis CA, Val P, Martinez A, Steroidogenic Factor-1 Lineage Origin of Skin Lesions in Carney Complex Syndrome. J Invest Dermatol. 2022 May 12; |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:134229 Shirohzu H, Okabe T, Gondo S, Tanaka T, Ohe K, Morinaga H, Kawate H, Nomura M, Takayanagi R, Nawata H, Yanase T, Methylation of a conserved intronic CpG island of mouse SF-1 is associated with cell-specific expression of SF-1 in a culture system but not with tissue-specific expression. Biochem Biophys Res Commun. 2008 May 9;369(3):862-7 |
1 | J:320700 Shtukmaster S, Narasimhan P, El Faitwri T, Stubbusch J, Ernsberger U, Rohrer H, Unsicker K, Huber K, MiR-124 is differentially expressed in derivatives of the sympathoadrenal cell lineage and promotes neurite elongation in chromaffin cells. Cell Tissue Res. 2016 Aug;365(2):225-32 |
1* | J:212053 Takasawa K, Kashimada K, Pelosi E, Takagi M, Morio T, Asahara H, Schlessinger D, Mizutani S, Koopman P, FOXL2 transcriptionally represses Sf1 expression by antagonizing WT1 during ovarian development in mice. FASEB J. 2014 May;28(5):2020-8 |
1 | J:83384 Tran PV, Lee MB, Marin O, Xu B, Jones KR, Reichardt LF, Rubenstein JR, Ingraham HA, Requirement of the orphan nuclear receptor SF-1 in terminal differentiation of ventromedial hypothalamic neurons. Mol Cell Neurosci. 2003 Apr;22(4):441-53 |
1 | J:108374 Vesper AH, Raetzman LT, Camper SA, Role of prophet of Pit1 (PROP1) in gonadotrope differentiation and puberty. Endocrinology. 2006 Apr;147(4):1654-63 |
1* | J:96928 Wilson MJ, Jeyasuria P, Parker KL, Koopman P, The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development. J Biol Chem. 2005 Feb 18;280(7):5917-23 |
1 | J:320691 Yadav VK, Berger JM, Singh P, Nagarajan P, Karsenty G, Embryonic osteocalcin signaling determines lifelong adrenal steroidogenesis and homeostasis in the mouse. J Clin Invest. 2022 Feb 15;132(4):e153752 |
1* | J:299732 Zhou X, Zhong S, Peng H, Liu J, Ding W, Sun L, Ma Q, Liu Z, Chen R, Wu Q, Wang X, Cellular and molecular properties of neural progenitors in the developing mammalian hypothalamus. Nat Commun. 2020 Aug 13;11(1):4063 |
Nr5a2 nuclear receptor subfamily 5, group A, member 2 (Synonyms: D1Ertd308e, Ftf, LRH-1, UF2-H3B) | |
Results | Reference |
1* | J:85764 Annicotte JS, Fayard E, Swift GH, Selander L, Edlund H, Tanaka T, Kodama T, Schoonjans K, Auwerx J, Pancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas development. Mol Cell Biol. 2003 Oct;23(19):6713-24 |
1 | J:170546 Kaltezioti V, Kouroupi G, Oikonomaki M, Mantouvalou E, Stergiopoulos A, Charonis A, Rohrer H, Matsas R, Politis PK, Prox1 regulates the notch1-mediated inhibition of neurogenesis. PLoS Biol. 2010;8(12):e1000565 |
1 | J:111670 Kyrmizi I, Hatzis P, Katrakili N, Tronche F, Gonzalez FJ, Talianidis I, Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev. 2006 Aug 15;20(16):2293-305 |
1 | J:241169 Stergiopoulos A, Politis PK, Nuclear receptor NR5A2 controls neural stem cell fate decisions during development. Nat Commun. 2016 Jul 22;7:12230 |
Nr6a1 nuclear receptor subfamily 6, group A, member 1 (Synonyms: 1700113M01Rik, Gcnf, NCNF) | |
Results | Reference |
1* | J:231259 Krill KT, Gurdziel K, Heaton JH, Simon DP, Hammer GD, Dicer deficiency reveals microRNAs predicted to control gene expression in the developing adrenal cortex. Mol Endocrinol. 2013 May;27(5):754-68 |
2* | J:221000 Sabour D, Xu X, Chung AC, Le Menuet D, Ko K, Tapia N, Arauzo-Bravo MJ, Gentile L, Greber B, Hubner K, Sebastiano V, Wu G, Scholer HR, Cooney AJ, Germ cell nuclear factor regulates gametogenesis in developing gonads. PLoS One. 2014;9(8):e103985 |
Nrap nebulin-related anchoring protein | |
Results | Reference |
1 | J:97478 Lu S, Borst DE, Horowits R, N-RAP expression during mouse heart development. Dev Dyn. 2005 May;233(1):201-12 |
1* | J:142599 Lu S, Borst DE, Horowits R, Expression and alternative splicing of N-RAP during mouse skeletal muscle development. Cell Motil Cytoskeleton. 2008 Dec;65(12):945-54 |
Nrarp Notch-regulated ankyrin repeat protein (Synonyms: 2700054M22Rik) | |
Results | Reference |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
Nras neuroblastoma ras oncogene (Synonyms: N-ras) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:320537 Newlaczyl AU, Coulson JM, Prior IA, Quantification of spatiotemporal patterns of Ras isoform expression during development. Sci Rep. 2017 Jan 24;7:41297 |
Nrcam neuronal cell adhesion molecule (Synonyms: Bravo, C030017F07Rik, C130076O07Rik, mKIAA0343) | |
Results | Reference |
3 | J:168542 Demyanenko GP, Riday TT, Tran TS, Dalal J, Darnell EP, Brennaman LH, Sakurai T, Grumet M, Philpot BD, Maness PF, NrCAM Deletion Causes Topographic Mistargeting of Thalamocortical Axons to the Visual Cortex and Disrupts Visual Acuity. J Neurosci. 2011 Jan 26;31(4):1545-1558 |
1* | J:263979 Harley RJ, Murdy JP, Wang Z, Kelly MC, Ropp TF, Park SH, Maness PF, Manis PB, Coate TM, Neuronal cell adhesion molecule (NrCAM) is expressed by sensory cells in the cochlea and is necessary for proper cochlear innervation and sensory domain patterning during development. Dev Dyn. 2018 Mar 14; |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1* | J:69842 Lustig M, Erskine L, Mason CA, Grumet M, Sakurai T, Nr-CAM expression in the developing mouse nervous system: ventral midline structures, specific fiber tracts, and neuropilar regions. J Comp Neurol. 2001 May 21;434(1):13-28 |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1 | J:122943 Williams SE, Grumet M, Colman DR, Henkemeyer M, Mason CA, Sakurai T, A role for Nr-CAM in the patterning of binocular visual pathways. Neuron. 2006 May 18;50(4):535-47 |
Nrdc nardilysin convertase (Synonyms: MGC:25477, Nrd1, NRD-C) | |
Results | Reference |
1* | J:45959 Fumagalli P, Accarino M, Egeo A, Scartezzini P, Rappazzo G, Pizzuti A, Avvantaggiato V, Simeone A, Arrigo G, Zuffardi O, Ottolenghi S, Taramelli R, Human NRD convertase: a highly conserved metalloendopeptidase expressed at specific sites during development and in adult tissues. Genomics. 1998 Jan 15;47(2):238-45 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Nrg1 neuregulin 1 (Synonyms: 6030402G23Rik, ARIA, D230005F13Rik, GGF, GGFII, heregulin, Hgl, HGL, HRG, HRGalpha, NDF, SMDF) | |
Results | Reference |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1 | J:355142 Gomez-Del Arco P, Isern J, Jimenez-Carretero D, Lopez-Maderuelo D, Pineiro-Sabaris R, El Abdellaoui-Soussi F, Torroja C, Vera-Pedrosa ML, Grima-Terren M, Benguria A, Simon-Chica A, Queiro-Palou A, Dopazo A, Sanchez-Cabo F, Jalife J, de la Pompa JL, Filgueiras-Rama D, Munoz-Canoves P, Redondo JM, The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development. Nat Commun. 2024 Oct 4;15(1):8602 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
2 | J:41235 Kaestner KH, Silberg DG, Traber PG, Schutz G, The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation. Genes Dev. 1997 Jun 15;11(12):1583-95 |
1 | J:102070 Liu J, Nethery D, Kern JA, Neuregulin-1 induces branching morphogenesis in the developing lung through a P13K signal pathway. Exp Lung Res. 2004 Sep;30(6):465-78 |
1 | J:273473 McKey J, Bunce C, Batchvarov IS, Ornitz DM, Capel B, Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5570-5575 |
1* | J:91711 Miyazaki Y, Nakanishi Y, Hieda Y, Tissue interaction mediated by neuregulin-1 and ErbB receptors regulates epithelial morphogenesis of mouse embryonic submandibular gland. Dev Dyn. 2004 Aug;230(4):591-6 |
1 | J:187102 Ortega MC, Bribian A, Peregrin S, Gil MT, Marin O, de Castro F, Neuregulin-1/ErbB4 signaling controls the migration of oligodendrocyte precursor cells during development. Exp Neurol. 2012 Jun;235(2):610-20 |
1 | J:161760 Provost PR, Simard M, Tremblay Y, A link between lung androgen metabolism and the emergence of mature epithelial type II cells. Am J Respir Crit Care Med. 2004 Aug 1;170(3):296-305 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
1 | J:180153 Veikkolainen V, Naillat F, Railo A, Chi L, Manninen A, Hohenstein P, Hastie N, Vainio S, Elenius K, ErbB4 Modulates Tubular Cell Polarity and Lumen Diameter during Kidney Development. J Am Soc Nephrol. 2012 Jan;23(1):112-22 |
Nrgn neurogranin (Synonyms: 0710001B06Rik, NG, NG/RC3, protein kinase C substrate, Pss1, RC3) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Nrip1 nuclear receptor interacting protein 1 (Synonyms: 6030458L20Rik, 8430438I05Rik, RIP140) | |
Results | Reference |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
Nrip2 nuclear receptor interacting protein 2 (Synonyms: NIX1) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Nrk Nik related kinase (Synonyms: Nesk) | |
Results | Reference |
2 | J:175907 Denda K, Nakao-Wakabayashi K, Okamoto N, Kitamura N, Ryu JY, Tagawa Y, Ichisaka T, Yamanaka S, Komada M, Nrk, an X-linked Protein Kinase in the Germinal Center Kinase Family, Is Required for Placental Development and Fetoplacental Induction of Labor. J Biol Chem. 2011 Aug 19;286(33):28802-10 |
Nrl neural retina leucine zipper gene | |
Results | Reference |
1 | J:285747 Liu S, Liu X, Li S, Huang X, Qian H, Jin K, Xiang M, Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5016-5027 |
1 | J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77 |
1* | J:71808 Swain PK, Hicks D, Mears AJ, Apel IJ, Smith JE, John SK, Hendrickson A, Milam AH, Swaroop A, Multiple phosphorylated isoforms of NRL are expressed in rod photoreceptors. J Biol Chem. 2001 Sep 28;276(39):36824-30 |
Nrn1 neuritin 1 (Synonyms: 0710008J23Rik, cpg15) | |
Results | Reference |
1* | J:101334 Kojima N, Shiojiri N, Sakai Y, Miyajima A, Expression of neuritin during liver maturation and regeneration. FEBS Lett. 2005 Aug 29;579(21):4562-6 |
Nrp1 neuropilin 1 (Synonyms: Neuropilin-1, NP-1, Npn1, NPN-1) | |
Results | Reference |
1 | J:183848 Benadiba C, Magnani D, Niquille M, Morle L, Valloton D, Nawabi H, Ait-Lounis A, Otsmane B, Reith W, Theil T, Hornung JP, Lebrand C, Durand B, The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development. PLoS Genet. 2012 Mar;8(3):e1002606 |
1 | J:332313 Cantu-Guerra HL, Papazian MR, Gorsky AL, Alekos NS, Caccavano A, Karagulyan N, Neef J, Vicini S, Moser T, Coate TM, Cochlear hair cell innervation is dependent on a modulatory function of Semaphorin-3A. Dev Dyn. 2023 Jan;252(1):124-144 |
1 | J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5 |
1 | J:119469 Fouquet C, Di Meglio T, Ma L, Kawasaki T, Long H, Hirata T, Tessier-Lavigne M, Chedotal A, Nguyen-Ba-Charvet KT, Robo1 and robo2 control the development of the lateral olfactory tract. J Neurosci. 2007 Mar 14;27(11):3037-45 |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1 | J:304874 Hatanaka Y, Matsumoto T, Yanagawa Y, Fujisawa H, Murakami F, Masu M, Distinct roles of neuropilin 1 signaling for radial and tangential extension of callosal axons. J Comp Neurol. 2009 May 20;514(3):215-25 |
1 | J:226381 Homman-Ludiye J, Bourne JA, The guidance molecule Semaphorin3A is differentially involved in the arealization of the mouse and primate neocortex. Cereb Cortex. 2014 Nov;24(11):2884-98 |
1 | J:278733 Hossain MM, Tsuzuki T, Sakakibara K, Imaizumi F, Ikegaya A, Inagaki M, Takahashi I, Ito T, Takamatsu H, Kumanogoh A, Negishi T, Yukawa K, PlexinA1 is crucial for the midline crossing of callosal axons during corpus callosum development in BALB/cAJ mice. PLoS One. 2019;14(8):e0221440 |
1 | J:94593 Inaki K, Nishimura S, Nakashiba T, Itohara S, Yoshihara Y, Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules. J Comp Neurol. 2004 Nov 15;479(3):243-56 |
1 | J:188056 Jameson SA, Lin YT, Capel B, Testis development requires the repression of Wnt4 by Fgf signaling. Dev Biol. 2012 Oct 1;370(1):24-32 |
2 | J:190719 Joza S, Wang J, Fox E, Hillman V, Ackerley C, Post M, Loss of semaphorin-neuropilin-1 signaling causes dysmorphic vascularization reminiscent of alveolar capillary dysplasia. Am J Pathol. 2012 Dec;181(6):2003-17 |
2* | J:30682 Kawakami A, Kitsukawa T, Takagi S, Fujisawa H, Developmentally regulated expression of a cell surface protein, neuropilin, in the mouse nervous system. J Neurobiol. 1996 Jan;29(1):1-17 |
1* | J:167053 Ko JA, Mizuno Y, Yanai R, Chikama T, Sonoda KH, Expression of semaphorin 3A and its receptors during mouse corneal development. Biochem Biophys Res Commun. 2010 Dec 17;403(3-4):305-9 |
2 | J:299731 Kohno T, Ishii K, Hirota Y, Honda T, Makino M, Kawasaki T, Nakajima K, Hattori M, Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner. J Neurosci. 2020 Oct 21;40(43):8248-8261 |
2* | J:226755 Lim JW, Donahoo AL, Bunt J, Edwards TJ, Fenlon LR, Liu Y, Zhou J, Moldrich RX, Piper M, Gobius I, Bailey TL, Wray NR, Kessaris N, Poo MM, Rubenstein JL, Richards LJ, EMX1 regulates NRP1-mediated wiring of the mouse anterior cingulate cortex. Development. 2015 Nov 1;142(21):3746-57 |
1* | J:68163 Loes S, Kettunen P, Kvinnsland IH, Taniguchi M, Fujisawa H, Luukko K, Expression of class 3 semaphorins and neuropilin receptors in the developing mouse tooth. Mech Dev. 2001 Mar;101(1-2):191-4 |
1* | J:74493 Maes C, Carmeliet P, Moermans K, Stockmans I, Smets N, Collen D, Bouillon R, Carmeliet G, Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF(164) and VEGF(188). Mech Dev. 2002 Feb;111(1-2):61-73 |
1 | J:217046 Magnani D, Hasenpusch-Theil K, Benadiba C, Yu T, Basson MA, Price DJ, Lebrand C, Theil T, Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Cereb Cortex. 2014 Jan;24(1):186-98 |
1 | J:260018 Mata A, Gil V, Perez-Clausell J, Dasilva M, Gonzalez-Calixto MC, Soriano E, Garcia-Verdugo JM, Sanchez-Vives MV, Del Rio JA, New functions of Semaphorin 3E and its receptor PlexinD1 during developing and adult hippocampal formation. Sci Rep. 2018 Jan 22;8(1):1381 |
1 | J:187230 McKenna CC, Munjaal RP, Lwigale PY, Distinct roles for neuropilin1 and neuropilin2 during mouse corneal innervation. PLoS One. 2012;7(5):e37175 |
1 | J:214759 McKenna CC, Ojeda AF, Spurlin J 3rd, Kwiatkowski S, Lwigale PY, Sema3A maintains corneal avascularity during development by inhibiting Vegf induced angioblast migration. Dev Biol. 2014 Jul 15;391(2):241-50 |
1 | J:310398 Mire E, Hocine M, Bazellieres E, Jungas T, Davy A, Chauvet S, Mann F, Developmental Upregulation of Ephrin-B1 Silences Sema3C/Neuropilin-1 Signaling during Post-crossing Navigation of Corpus Callosum Axons. Curr Biol. 2018 Jun 4;28(11):1768-1782.e4 |
1 | J:154587 Niquille M, Garel S, Mann F, Hornung JP, Otsmane B, Chevalley S, Parras C, Guillemot F, Gaspar P, Yanagawa Y, Lebrand C, Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C. PLoS Biol. 2009 Oct;7(10):e1000230 |
1 | J:149553 Pecho-Vrieseling E, Sigrist M, Yoshida Y, Jessell TM, Arber S, Specificity of sensory-motor connections encoded by Sema3e-Plxnd1 recognition. Nature. 2009 Jun 11;459(7248):842-6 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:70742 Pozas E, Pascual M, Tuyen Nguyen Ba-Charvet K, Guijarro P, Sotelo C, Chedotal A, Del Rio JA, Soriano E, Age-dependent effects of secreted semaphorins 3a, 3f, and 3e on developing hippocampal axons: in vitro effects and phenotype of semaphorin 3a (-/-) mice. Mol Cell Neurosci. 2001 Jul;18(1):26-43 |
1 | J:208409 Reinert RB, Cai Q, Hong JY, Plank JL, Aamodt K, Prasad N, Aramandla R, Dai C, Levy SE, Pozzi A, Labosky PA, Wright CV, Brissova M, Powers AC, Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding. Development. 2014 Apr;141(7):1480-91 |
1 | J:206997 Ruediger T, Zimmer G, Barchmann S, Castellani V, Bagnard D, Bolz J, Integration of opposing semaphorin guidance cues in cortical axons. Cereb Cortex. 2013 Mar;23(3):604-14 |
1 | J:248731 Salehi P, Ge MX, Gundimeda U, Michelle Baum L, Lael Cantu H, Lavinsky J, Tao L, Myint A, Cruz C, Wang J, Nikolakopoulou AM, Abdala C, Kelley MW, Ohyama T, Coate TM, Friedman RA, Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea. PLoS Genet. 2017 Oct;13(10):e1007048 |
1 | J:235507 Stewart CE, Corella KM, Samberg BD, Jones PT, Linscott ML, Chung WC, Perinatal midline astrocyte development is impaired in fibroblast growth factor 8 hypomorphic mice. Brain Res. 2016 Sep 1;1646:287-96 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
2 | J:130566 Wright AG, Demyanenko GP, Powell A, Schachner M, Enriquez-Barreto L, Tran TS, Polleux F, Maness PF, Close homolog of L1 and neuropilin 1 mediate guidance of thalamocortical axons at the ventral telencephalon. J Neurosci. 2007 Dec 12;27(50):13667-79 |
Nrp2 neuropilin 2 (Synonyms: 1110048P06Rik, NP-2, NP2, Npn-2, Npn2) | |
Results | Reference |
2 | J:269938 Bovay E, Sabine A, Prat-Luri B, Kim S, Son K, Willrodt AH, Olsson C, Halin C, Kiefer F, Betsholtz C, Jeon NL, Luther SA, Petrova TV, Multiple roles of lymphatic vessels in peripheral lymph node development. J Exp Med. 2018 Nov 5;215(11):2760-2777 |
1 | J:297714 Brignani S, Raj DDA, Schmidt ERE, Dudukcu O, Adolfs Y, De Ruiter AA, Rybiczka-Tesulov M, Verhagen MG, van der Meer C, Broekhoven MH, Moreno-Bravo JA, Grossouw LM, Dumontier E, Cloutier JF, Chedotal A, Pasterkamp RJ, Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development. Neuron. 2020 Aug 19;107(4):684-702.e9 |
1 | J:233304 Cha B, Geng X, Mahamud MR, Fu J, Mukherjee A, Kim Y, Jho EH, Kim TH, Kahn ML, Xia L, Dixon JB, Chen H, Srinivasan RS, Mechanotransduction activates canonical Wnt/beta-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves. Genes Dev. 2016 Jun 15;30(12):1454-69 |
1 | J:226819 Coate TM, Spita NA, Zhang KD, Isgrig KT, Kelley MW, Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife. 2015;4 |
1 | J:126582 Cobos I, Borello U, Rubenstein JL, Dlx transcription factors promote migration through repression of axon and dendrite growth. Neuron. 2007 Jun 21;54(6):873-88 |
1 | J:59284 Galceran J, Miyashita-Lin EM, Devaney E, Rubenstein JL, Grosschedl R, Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1. Development. 2000 Feb;127(3):469-82 |
1 | J:266493 Gauvrit S, Villasenor A, Strilic B, Kitchen P, Collins MM, Marin-Juez R, Guenther S, Maischein HM, Fukuda N, Canham MA, Brickman JM, Bogue CW, Jayaraman PS, Stainier DYR, HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development. Nat Commun. 2018 Jul 13;9(1):2704 |
2 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1 | J:94593 Inaki K, Nishimura S, Nakashiba T, Itohara S, Yoshihara Y, Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules. J Comp Neurol. 2004 Nov 15;479(3):243-56 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
2* | J:123566 Le TN, Du G, Fonseca M, Zhou QP, Wigle JT, Eisenstat DD, Dlx homeobox genes promote cortical interneuron migration from the basal forebrain by direct repression of the semaphorin receptor neuropilin-2. J Biol Chem. 2007 Jun 29;282(26):19071-81 |
1 | J:178118 Li Q, Bian S, Hong J, Kawase-Koga Y, Zhu E, Zheng Y, Yang L, Sun T, Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development. PLoS One. 2011;6(10):e26000 |
1 | J:244674 Liu X, Pasula S, Song H, Tessneer KL, Dong Y, Hahn S, Yago T, Brophy ML, Chang B, Cai X, Wu H, McManus J, Ichise H, Georgescu C, Wren JD, Griffin C, Xia L, Srinivasan RS, Chen H, Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function. Sci Signal. 2014 Oct 14;7(347):ra97 |
1* | J:68163 Loes S, Kettunen P, Kvinnsland IH, Taniguchi M, Fujisawa H, Luukko K, Expression of class 3 semaphorins and neuropilin receptors in the developing mouse tooth. Mech Dev. 2001 Mar;101(1-2):191-4 |
1 | J:316129 Login H, Butowt R, Bohm S, Activity-dependent and graded BACE1 expression in the olfactory epithelium is mediated by the retinoic acid metabolizing enzyme CYP26B1. Brain Struct Funct. 2015 Jul;220(4):2143-57 |
1 | J:260018 Mata A, Gil V, Perez-Clausell J, Dasilva M, Gonzalez-Calixto MC, Soriano E, Garcia-Verdugo JM, Sanchez-Vives MV, Del Rio JA, New functions of Semaphorin 3E and its receptor PlexinD1 during developing and adult hippocampal formation. Sci Rep. 2018 Jan 22;8(1):1381 |
1 | J:187230 McKenna CC, Munjaal RP, Lwigale PY, Distinct roles for neuropilin1 and neuropilin2 during mouse corneal innervation. PLoS One. 2012;7(5):e37175 |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
1 | J:308707 Paulson D, Harms R, Ward C, Latterell M, Pazour GJ, Fink DM, Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation. Front Cell Dev Biol. 2021;9:672625 |
1 | J:264119 Pichol-Thievend C, Betterman KL, Liu X, Ma W, Skoczylas R, Lesieur E, Bos FL, Schulte D, Schulte-Merker S, Hogan BM, Oliver G, Harvey NL, Francois M, A blood capillary plexus-derived population of progenitor cells contributes to genesis of the dermal lymphatic vasculature during embryonic development. Development. 2018 May 17;145(10):dev160184 |
1 | J:70742 Pozas E, Pascual M, Tuyen Nguyen Ba-Charvet K, Guijarro P, Sotelo C, Chedotal A, Del Rio JA, Soriano E, Age-dependent effects of secreted semaphorins 3a, 3f, and 3e on developing hippocampal axons: in vitro effects and phenotype of semaphorin 3a (-/-) mice. Mol Cell Neurosci. 2001 Jul;18(1):26-43 |
1 | J:154741 Prince JE, Cho JH, Dumontier E, Andrews W, Cutforth T, Tessier-Lavigne M, Parnavelas J, Cloutier JF, Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. J Neurosci. 2009 Nov 11;29(45):14211-22 |
1 | J:269234 Pujol F, Hodgson T, Martinez-Corral I, Prats AC, Devenport D, Takeichi M, Genot E, Makinen T, Francis-West P, Garmy-Susini B, Tatin F, Dachsous1-Fat4 Signaling Controls Endothelial Cell Polarization During Lymphatic Valve Morphogenesis-Brief Report. Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1732-1735 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1 | J:296443 Rondon-Galeano M, Skoczylas R, Bower NI, Simons C, Gordon E, Francois M, Koltowska K, Hogan BM, MAFB modulates the maturation of lymphatic vascular networks in mice. Dev Dyn. 2020 Oct;249(10):1201-1216 |
1 | J:206997 Ruediger T, Zimmer G, Barchmann S, Castellani V, Bagnard D, Bolz J, Integration of opposing semaphorin guidance cues in cortical axons. Cereb Cortex. 2013 Mar;23(3):604-14 |
1 | J:336383 Ruiz-Reig N, Andres B, Huilgol D, Grove EA, Tissir F, Tole S, Theil T, Herrera E, Fairen A, Lateral Thalamic Eminence: A Novel Origin for mGluR1/Lot Cells. Cereb Cortex. 2017 May 1;27(5):2841-2856 |
1 | J:181330 Sabine A, Agalarov Y, Maby-El Hajjami H, Jaquet M, Hagerling R, Pollmann C, Bebber D, Pfenniger A, Miura N, Dormond O, Calmes JM, Adams RH, Makinen T, Kiefer F, Kwak BR, Petrova TV, Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation. Dev Cell. 2012 Feb 14;22(2):430-45 |
1 | J:167943 Takeuchi H, Inokuchi K, Aoki M, Suto F, Tsuboi A, Matsuda I, Suzuki M, Aiba A, Serizawa S, Yoshihara Y, Fujisawa H, Sakano H, Sequential arrival and graded secretion of Sema3F by olfactory neuron axons specify map topography at the bulb. Cell. 2010 Jun 11;141(6):1056-67 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1 | J:214891 Torigoe M, Yamauchi K, Tamada A, Matsuda I, Aiba A, Castellani V, Murakami F, Role of neuropilin-2 in the ipsilateral growth of midbrain dopaminergic axons. Eur J Neurosci. 2013 May;37(10):1573-83 |
1 | J:197638 van den Berghe V, Stappers E, Vandesande B, Dimidschstein J, Kroes R, Francis A, Conidi A, Lesage F, Dries R, Cazzola S, Berx G, Kessaris N, Vanderhaeghen P, van Ijcken W, Grosveld FG, Goossens S, Haigh JJ, Fishell G, Goffinet A, Aerts S, Huylebroeck D, Seuntjens E, Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1. Neuron. 2013 Jan 9;77(1):70-82 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:159315 Xie Z, Ma X, Ji W, Zhou G, Lu Y, Xiang Z, Wang YX, Zhang L, Hu Y, Ding YQ, Zhang WJ, Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6510-5 |
1* | J:75934 Zelzer E, McLean W, Ng YS, Fukai N, Reginato AM, Lovejoy S, D'Amore PA, Olsen BR, Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development. 2002 Apr;129(8):1893-904 |
Nrtn neurturin | |
Results | Reference |
1 | J:50254 Luukko K, Saarma M, Thesleff I, Neurturin mRNA expression suggests roles in trigeminal innervation of the first branchial arch and in tooth formation. Dev Dyn. 1998 Oct;213(2):207-19 |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Nrxn2 neurexin II (Synonyms: 6430591O13Rik, mKIAA0921, neurexin II alpha, neurexin II beta) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Nrxn3 neurexin III (Synonyms: 4933401A11Rik, 9330112C09Rik, D12Bwg0831e, neurexin III alpha, neurexin III alpha, neurexin III beta, neurexin III beta) | |
Results | Reference |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Nsd1 nuclear receptor-binding SET-domain protein 1 (Synonyms: KMT3B) | |
Results | Reference |
1 | J:346179 Abe S, Nagatomo H, Sasaki H, Ishiuchi T, A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation. Epigenetics. 2021 Oct;16(10):1123-1134 |
1 | J:83923 Rayasam GV, Wendling O, Angrand PO, Mark M, Niederreither K, Song L, Lerouge T, Hager GL, Chambon P, Losson R, NSD1 is essential for early post-implantation development and has a catalytically active SET domain. EMBO J. 2003 Jun 16;22(12):3153-63 |
2 | J:344238 Zheng Y, Zhao C, Song Q, Xu L, Zhang B, Hu G, Kong X, Li S, Li X, Shen Y, Zhuang L, Wu M, Liu Y, Zhou Y, Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities. Cell Rep. 2023 Dec 26;42(12):113496 |
Nsd2 nuclear receptor binding SET domain protein 2 (Synonyms: 5830445G22Rik, 9430010A17Rik, C130020C13Rik, D030027O06Rik, D930023B08Rik, mKIAA1090, Whsc1, Whsc1l) | |
Results | Reference |
1 | J:346179 Abe S, Nagatomo H, Sasaki H, Ishiuchi T, A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation. Epigenetics. 2021 Oct;16(10):1123-1134 |
2 | J:342842 Su D, Eliason S, Sun Z, Shao F, Amendt BA, Wolf-Hirschhorn syndrome candidate 1 (Whsc1) methyltransferase signals via a Pitx2-miR-23/24 axis to effect tooth development. J Biol Chem. 2023 Nov;299(11):105324 |
Nsdhl NAD(P) dependent steroid dehydrogenase-like (Synonyms: bare patches, Bpa, H105E3, Str, striated, XAP104) | |
Results | Reference |
2* | J:155028 Cunningham D, Spychala K, McLarren KW, Garza LA, Boerkoel CF, Herman GE, Developmental expression pattern of the cholesterogenic enzyme NSDHL and negative selection of NSDHL-deficient cells in the heterozygous Bpa(1H)/+ mouse. Mol Genet Metab. 2009 Dec;98(4):356-66 |
1* | J:55488 Liu XY, Dangel AW, Kelley RI, Zhao W, Denny P, Botcherby M, Cattanach B , Peters J , Hunsicker PR , Mallon AM , Strivens MA , Bate R , Miller W , Rhodes M , Brown SD , Herman GE, The gene mutated in bare patches and striated mice encodes a novel 3beta-hydroxysteroid dehydrogenase. Nat Genet. 1999 Jun;22(2):182-7 |
Nsf N-ethylmaleimide sensitive fusion protein (Synonyms: N-ethylmaleimide sensitive factor, SKD2) | |
Results | Reference |
1* | J:335231 Bustamante-Barrientos FA, Mendez-Ruette M, Molina L, Koning T, Ehrenfeld P, Gonzalez CB, Wyneken U, Henzi R, Batiz LF, Alpha-SNAP (M105I) mutation promotes neuronal differentiation of neural stem/progenitor cells through overactivation of AMPK. Front Cell Dev Biol. 2023;11:1061777 |
Nsg1 neuron specific gene family member 1 (Synonyms: m234, NEEP21, p21) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Nsun2 NOL1/NOP2/Sun domain family member 2 (Synonyms: Misu) | |
Results | Reference |
1 | J:179810 Blanco S, Kurowski A, Nichols J, Watt FM, Benitah SA, Frye M, The RNA-methyltransferase Misu (NSun2) poises epidermal stem cells to differentiate. PLoS Genet. 2011 Dec;7(12):e1002403 |
1 | J:203322 Hussain S, Tuorto F, Menon S, Blanco S, Cox C, Flores JV, Watt S, Kudo NR, Lyko F, Frye M, The mouse cytosine-5 RNA methyltransferase NSun2 is a component of the chromatoid body and required for testis differentiation. Mol Cell Biol. 2013 Apr;33(8):1561-70 |
Nsun5 NOL1/NOP2/Sun domain family, member 5 (Synonyms: 9830109N13Rik, Nol1r, Wbscr20a) | |
Results | Reference |
3 | J:282264 Chen P, Zhang T, Yuan Z, Shen B, Chen L, Expression of the RNA methyltransferase Nsun5 is essential for developing cerebral cortex. Mol Brain. 2019 Aug 28;12(1):74 |
1* | J:306325 Wang Y, Jiang T, Xu J, Gu Y, Zhou Y, Lin Y, Wu Y, Li W, Wang C, Shen B, Mo X, Wang X, Zhou B, Ding C, Hu Z, Mutations in RNA Methyltransferase Gene NSUN5 Confer High Risk of Outflow Tract Malformation. Front Cell Dev Biol. 2021;9:623394 |
Nt5c3 5'-nucleotidase, cytosolic III (Synonyms: 1600024P05Rik, 2610206B05Rik, cN-III, lupin, p36, PN-1, PN-I, PSN1, Umph-1, Umph1) | |
Results | Reference |
1* | J:65244 Lu MM, Chen F, Gitler A, Li J, Jin F, Ma XK, Epstein JA, Cloning and expression analysis of murine lupin, a member of a novel gene family that is conserved through evolution and associated with Lupus inclusions. Dev Genes Evol. 2000 Oct;210(10):512-7 |
Nt5dc2 5'-nucleotidase domain containing 2 (Synonyms: 2510015F01Rik) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
Nt5e 5' nucleotidase, ecto (Synonyms: 2210401F01Rik, CD73, ecto-5'-nucleotidase, Nt5) | |
Results | Reference |
1 | J:13214 Schoen SW, Graybiel AM, Species-specific patterns of glycoprotein expression in the developing rodent caudoputamen: association of 5'-nucleotidase activity with dopamine islands and striosomes in rat, but with extrastriosomal matrix in mouse. J Comp Neurol. 1993 Jul 22;333(4):578-96 |
Ntf3 neurotrophin 3 (Synonyms: NT-3, NT3, Ntf-3) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:72516 Pirvola U, Spencer-Dene B, Xing-Qun L, Kettunen P, Thesleff I, Fritzsch B, Dickson C, Ylikoski J, FGF/FGFR-2(IIIb) signaling is essential for inner ear morphogenesis. J Neurosci. 2000 Aug 15;20(16):6125-34 |
1 | J:86789 Szeder V, Grim M, Kucera J, Sieber-Blum M, Neurotrophin-3 signaling in mammalian Merkel cell development. Dev Dyn. 2003 Dec;228(4):623-9 |
1 | J:67935 Taylor MD, Vancura R, Patterson CL, Williams JM, Riekhof JT, Wright DE, Postnatal regulation of limb proprioception by muscle-derived neurotrophin-3. J Comp Neurol. 2001 Apr 2;432(2):244-58 |
1* | J:84657 Vigers AJ, Bottger B, Baquet ZC, Finger TE, Jones KR, Neurotrophin-3 is expressed in a discrete subset of olfactory receptor neurons in the mouse. J Comp Neurol. 2003 Aug 18;463(2):221-35 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Ntf5 neurotrophin 5 (Synonyms: 2900040K06Rik, neurotrophin-4, NT-4, NT4, NT4/5, Ntf4, Ntf-5) | |
Results | Reference |
1* | J:157986 Childs AJ, Bayne RA, Murray AA, Martins Da Silva SJ, Collins CS, Spears N, Anderson RA, Differential expression and regulation by activin of the neurotrophins BDNF and NT4 during human and mouse ovarian development. Dev Dyn. 2010 Feb 19;239(4):1211-1219 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:165547 Huang T, Krimm RF, Developmental expression of Bdnf, Ntf4/5, and TrkB in the mouse peripheral taste system. Dev Dyn. 2010 Oct;239(10):2637-46 |
1* | J:85731 Spears N, Molinek MD, Robinson LL, Fulton N, Cameron H, Shimoda K, Telfer EE, Anderson RA, Price DJ, The role of neurotrophin receptors in female germ-cell survival in mouse and human. Development. 2003 Nov;130(22):5481-91 |
Ntm neurotrimin (Synonyms: 6230410L23Rik, B230210G24Rik, Hnt) | |
Results | Reference |
1 | J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400 |
1* | J:312430 Fearnley S, Raja R, Cloutier JF, Spatiotemporal expression of IgLON family members in the developing mouse nervous system. Sci Rep. 2021 Oct 1;11(1):19536 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
2 | J:361603 Scavuzzo MA, Szlachcic WJ, Hill MC, Ziojla NM, Teaw J, Carlson JC, Tiessen J, Chmielowiec J, Martin JF, Borowiak M, Pancreatic organogenesis mapped through space and time. Exp Mol Med. 2025 Feb;57(1):204-220 |
Ntn1 netrin 1 (Synonyms: Netrin-1) | |
Results | Reference |
1* | J:65295 Barallobre MJ, Del Rio JA, Alcantara S, Borrell V, Aguado F, Ruiz M, Carmona MA, Martin M, Fabre M, Yuste R, Tessier-Lavigne M, Soriano E, Aberrant development of hippocampal circuits and altered neural activity in netrin 1-deficient mice. Development. 2000 Nov;127(22):4797-810 |
1* | J:60855 Birgbauer E, Cowan CA, Sretavan DW, Henkemeyer M, Kinase independent function of EphB receptors in retinal axon pathfinding to the optic disc from dorsal but not ventral retina. Development. 2000 Mar;127(6):1231-41 |
1* | J:121833 Bonnin A, Torii M, Wang L, Rakic P, Levitt P, Serotonin modulates the response of embryonic thalamocortical axons to netrin-1. Nat Neurosci. 2007 May;10(5):588-97 |
1 | J:309347 Botella-Lopez A, Garcia-Lopez R, Pombero A, Martinez S, Radial glia fibers translate Fgf8 morphogenetic signals to generate a thalamic nuclear complex protomap in the mantle layer. Brain Struct Funct. 2019 Mar;224(2):661-679 |
2 | J:297714 Brignani S, Raj DDA, Schmidt ERE, Dudukcu O, Adolfs Y, De Ruiter AA, Rybiczka-Tesulov M, Verhagen MG, van der Meer C, Broekhoven MH, Moreno-Bravo JA, Grossouw LM, Dumontier E, Cloutier JF, Chedotal A, Pasterkamp RJ, Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development. Neuron. 2020 Aug 19;107(4):684-702.e9 |
1 | J:83530 Dakubo GD, Wang YP, Mazerolle C, Campsall K, McMahon AP, Wallace VA, Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development. Development. 2003 Jul;130(13):2967-80 |
2* | J:84360 Dalvin S, Anselmo MA, Prodhan P, Komatsuzaki K, Schnitzer JJ, Kinane TB, Expression of Netrin-1 and its two receptors DCC and UNC5H2 in the developing mouse lung. Gene Expr Patterns. 2003 Jun;3(3):279-83 |
1 | J:58438 Deiner MS, Sretavan DW, Altered midline axon pathways and ectopic neurons in the developing hypothalamus of netrin-1- and DCC-deficient mice. J Neurosci. 1999 Nov 15;19(22):9900-12 |
1 | J:44591 Garel S, Marin F, Grosschedl R, Charnay P, Ebf1 controls early cell differentiation in the embryonic striatum. Development. 1999 Dec;126(23):5285-94 |
1 | J:229411 Hakanen J, Salminen M, Defects in neural guidepost structures and failure to remove leptomeningeal cells from the septal midline behind the interhemispheric fusion defects in Netrin1 deficient mice. Int J Dev Neurosci. 2015 Dec;47(Pt B):206-15 |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
1 | J:235517 Kam JW, Dumontier E, Baim C, Brignall AC, Mendes da Silva D, Cowan M, Kennedy TE, Cloutier JF, RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016 May 1;143(9):1534-46 |
1 | J:107863 Kubota C, Nagano T, Baba H, Sato M, Netrin-1 is crucial for the establishment of the dorsal column-medial lemniscal system. J Neurochem. 2004 Jun;89(6):1547-54 |
1 | J:217604 Lavado A, Ware M, Pare J, Cao X, The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Development. 2014 Nov;141(21):4182-93 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1 | J:201154 Meziane H, Fraulob V, Riet F, Krezel W, Selloum M, Geffarth M, Acampora D, Herault Y, Simeone A, Brand M, Dolle P, Rhinn M, The homeodomain factor Gbx1 is required for locomotion and cell specification in the dorsal spinal cord. PeerJ. 2013;1:e142 |
1 | J:140549 Ratcliffe EM, Setru SU, Chen JJ, Li ZS, D'Autreaux F, Gershon MD, Netrin/DCC-mediated attraction of vagal sensory axons to the fetal mouse gut. J Comp Neurol. 2006 Oct 10;498(5):567-80 |
1 | J:215618 Schmidt ER, Brignani S, Adolfs Y, Lemstra S, Demmers J, Vidaki M, Donahoo AL, Lillevali K, Vasar E, Richards LJ, Karagogeos D, Kolk SM, Pasterkamp RJ, Subdomain-mediated axon-axon signaling and chemoattraction cooperate to regulate afferent innervation of the lateral habenula. Neuron. 2014 Jul 16;83(2):372-87 |
1* | J:37125 Serafini T, Colamarino SA, Leonardo ED, Wang H, Beddington R, Skarnes WC, Tessier-Lavigne M, Netrin-1 is required for commissural axon guidance in the developing vertebrate nervous system. Cell. 1996 Dec 13;87(6):1001-14 |
1 | J:142435 Shi M, Guo C, Dai JX, Ding YQ, DCC is required for the tangential migration of noradrenergic neurons in locus coeruleus of mouse brain. Mol Cell Neurosci. 2008 Dec;39(4):529-38 |
1 | J:357469 Sivori M, Dempsey B, Chettouh Z, Boismoreau F, Ayerdi M, et al., The pelvic organs receive no parasympathetic innervation. Elife. 2024;15 |
1 | J:110263 Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM, Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat Neurosci. 2006 Jun;9(6):787-97 |
1 | J:64211 Vitalis T, Cases O, Engelkamp D, Verney C, Price DJ, Defect of tyrosine hydroxylase-immunoreactive neurons in the brains of mice lacking the transcription factor Pax6. J Neurosci. 2000 Sep 1;20(17):6501-16 |
1 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
Ntn3 netrin 3 (Synonyms: Ntn2l, Ntn3) | |
Results | Reference |
2* | J:55480 Wang H, Copeland NG, Gilbert DJ, Jenkins NA, Tessier-Lavigne M, Netrin-3, a mouse homolog of human NTN2L, is highly expressed in sensory ganglia and shows differential binding to netrin receptors. J Neurosci. 1999 Jun 15;19(12):4938-47 |
Ntn4 netrin 4 (Synonyms: beta-netrin) | |
Results | Reference |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Ntng1 netrin G1 (Synonyms: A930010C08Rik, Lmnt1) | |
Results | Reference |
1 | J:171595 Bonnin A, Goeden N, Chen K, Wilson ML, King J, Shih JC, Blakely RD, Deneris ES, Levitt P, A transient placental source of serotonin for the fetal forebrain. Nature. 2011 Apr 21;472(7343):347-50 |
1 | J:306056 Doyle DZ, Lam MM, Qalieh A, Qalieh Y, Sorel A, Funk OH, Kwan KY, Chromatin remodeler Arid1a regulates subplate neuron identity and wiring of cortical connectivity. Proc Natl Acad Sci U S A. 2021 May 25;118(21):e2100686118 |
1 | J:208050 Huang TN, Chuang HC, Chou WH, Chen CY, Wang HF, Chou SJ, Hsueh YP, Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality. Nat Neurosci. 2014 Feb;17(2):240-7 |
1 | J:94593 Inaki K, Nishimura S, Nakashiba T, Itohara S, Yoshihara Y, Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules. J Comp Neurol. 2004 Nov 15;479(3):243-56 |
1 | J:284900 Larsen R, Proue A, Scott EP, Christiansen M, Nakagawa Y, The Thalamus Regulates Retinoic Acid Signaling and Development of Parvalbumin Interneurons in Postnatal Mouse Prefrontal Cortex. eNeuro. 2019 Jan-Feb;6(1):ENEURO.0018-19.2019 |
1 | J:331478 Monko T, Rebertus J, Stolley J, Salton SR, Nakagawa Y, Thalamocortical axons regulate neurogenesis and laminar fates in the early sensory cortex. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2201355119 |
1* | J:74494 Nakashiba T, Nishimura S, Ikeda T, Itohara S, Complementary expression and neurite outgrowth activity of netrin-G subfamily members. Mech Dev. 2002 Feb;111(1-2):47-60 |
1 | J:234107 Saito Y, Miranda-Rottmann S, Ruggiu M, Park CY, Fak JJ, Zhong R, Duncan JS, Fabella BA, Junge HJ, Chen Z, Araya R, Fritzsch B, Hudspeth AJ, Darnell RB, NOVA2-mediated RNA regulation is required for axonal pathfinding during development. Elife. 2016;5:e14371 |
1 | J:198431 Vue TY, Lee M, Tan YE, Werkhoven Z, Wang L, Nakagawa Y, Thalamic control of neocortical area formation in mice. J Neurosci. 2013 May 8;33(19):8442-53 |
Ntng2 netrin G2 (Synonyms: 2610016D08Rik, Lmnt2) | |
Results | Reference |
1* | J:74494 Nakashiba T, Nishimura S, Ikeda T, Itohara S, Complementary expression and neurite outgrowth activity of netrin-G subfamily members. Mech Dev. 2002 Feb;111(1-2):47-60 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Ntrk1 neurotrophic tyrosine kinase, receptor, type 1 (Synonyms: Tkr, TrkA) | |
Results | Reference |
1 | J:78232 Arber S, Ladle DR, Lin JH, Frank E, Jessell TM, ETS gene Er81 controls the formation of functional connections between group Ia sensory afferents and motor neurons. Cell. 2000 May 26;101(5):485-98 |
1 | J:178481 Bachy I, Franck MC, Li L, Abdo H, Pattyn A, Ernfors P, The transcription factor Cux2 marks development of an A-delta sublineage of TrkA sensory neurons. Dev Biol. 2011 Dec 1;360(1):77-86 |
1 | J:65040 Botchkareva NV, Botchkarev VA, Albers KM, Metz M, Paus R, Distinct roles for nerve growth factor and brain-derived neurotrophic factor in controlling the rate of hair follicle morphogenesis. J Invest Dermatol. 2000 Feb;114(2):314-20 |
2 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1 | J:70560 Chen Z, Rebelo S, White F, Malmberg AB, Baba H, Lima D, Woolf CJ, Basbaum AI, Anderson DJ, The paired homeodomain protein drg11 is required for the projection of cutaneous sensory afferent fibers to the dorsal spinal cord. Neuron. 2001 Jul 19;31(1):59-73 |
1 | J:313341 Comer JD, Pan FC, Willet SG, Haldipur P, Millen KJ, Wright CV, Kaltschmidt JA, Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3. Front Neural Circuits. 2015;9:36 |
1 | J:283226 Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld KA, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ, Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA. Cell Rep. 2019 Mar 26;26(13):3522-3536.e5 |
1 | J:345844 Guo Y, Xiang P, Sun X, Liu W, Zhou J, Yin B, Hou L, Qiang B, Li H, Shu P, Peng X, Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy. Signal Transduct Target Ther. 2024 Feb 14;9(1):32 |
1 | J:315755 Hancock ML, Nowakowski DW, Role LW, Talmage DA, Flanagan JG, Type III neuregulin 1 regulates pathfinding of sensory axons in the developing spinal cord and periphery. Development. 2011 Nov;138(22):4887-98 |
2 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1 | J:161851 Honma Y, Kawano M, Kohsaka S, Ogawa M, Axonal projections of mechanoreceptive dorsal root ganglion neurons depend on Ret. Development. 2010 Jul;137(14):2319-28 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
1 | J:184011 John A, Brylka H, Wiegreffe C, Simon R, Liu P, Juttner R, Crenshaw EB 3rd, Luyten FP, Jenkins NA, Copeland NG, Birchmeier C, Britsch S, Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. Development. 2012 May;139(10):1831-41 |
1 | J:37118 McEvilly RJ, Erkman L, Luo L, Sawchenko PE, Ryan AF, Rosenfeld MG, Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature. 1996 Dec 12;384(6609):574-7 |
1 | J:213126 O'Donovan KJ, Ma K, Guo H, Wang C, Sun F, Han SB, Kim H, Wong JK, Charron J, Zou H, Son YJ, He Z, Zhong J, B-RAF kinase drives developmental axon growth and promotes axon regeneration in the injured mature CNS. J Exp Med. 2014 May 5;211(5):801-14 |
1 | J:149553 Pecho-Vrieseling E, Sigrist M, Yoshida Y, Jessell TM, Arber S, Specificity of sensory-motor connections encoded by Sema3e-Plxnd1 recognition. Nature. 2009 Jun 11;459(7248):842-6 |
1 | J:217530 Renier N, Wu Z, Simon DJ, Yang J, Ariel P, Tessier-Lavigne M, iDISCO: a simple, rapid method to immunolabel large tissue samples for volume imaging. Cell. 2014 Nov 6;159(4):896-910 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
2 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
1 | J:237233 Tomlinson RE, Li Z, Zhang Q, Goh BC, Li Z, Thorek DL, Rajbhandari L, Brushart TM, Minichiello L, Zhou F, Venkatesan A, Clemens TL, NGF-TrkA Signaling by Sensory Nerves Coordinates the Vascularization and Ossification of Developing Endochondral Bone. Cell Rep. 2016 Sep 06;16(10):2723-35 |
2 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
1 | J:196947 Wildner H, Das Gupta R, Brohl D, Heppenstall PA, Zeilhofer HU, Birchmeier C, Genome-wide expression analysis of Ptf1a- and Ascl1-deficient mice reveals new markers for distinct dorsal horn interneuron populations contributing to nociceptive reflex plasticity. J Neurosci. 2013 Apr 24;33(17):7299-307 |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
1 | J:207050 Zhao X, Huang H, Chen Y, Liu Y, Zhang Z, Ma Q, Qiu M, Dynamic expression of secreted Frizzled-related protein 3 (sFRP3) in the developing mouse spinal cord and dorsal root ganglia. Neuroscience. 2013 Sep 17;248:594-601 |
Ntrk2 neurotrophic tyrosine kinase, receptor, type 2 (Synonyms: C030027L06Rik, Tkrb, trkB) | |
Results | Reference |
1 | J:168326 Baydyuk M, Russell T, Liao GY, Zang K, An JJ, Reichardt LF, Xu B, TrkB receptor controls striatal formation by regulating the number of newborn striatal neurons. Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1669-74 |
1 | J:65040 Botchkareva NV, Botchkarev VA, Albers KM, Metz M, Paus R, Distinct roles for nerve growth factor and brain-derived neurotrophic factor in controlling the rate of hair follicle morphogenesis. J Invest Dermatol. 2000 Feb;114(2):314-20 |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1 | J:172162 de Melo J, Zhou QP, Zhang Q, Zhang S, Fonseca M, Wigle JT, Eisenstat DD, Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development. Nucleic Acids Res. 2008 Feb;36(3):872-84 |
1 | J:353354 Desiderio S, Schwaller F, Tartour K, Padmanabhan K, Lewin GR, Carroll P, Marmigere F, Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2. Elife. 2024 Feb 22;12 |
1 | J:283226 Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld KA, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ, Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA. Cell Rep. 2019 Mar 26;26(13):3522-3536.e5 |
1* | J:296604 Durbeej M, Soderstrom S, Ebendal T, Birchmeier C, Ekblom P, Differential expression of neurotrophin receptors during renal development. Development. 1993 Dec;119(4):977-89 |
1 | J:345844 Guo Y, Xiang P, Sun X, Liu W, Zhou J, Yin B, Hou L, Qiang B, Li H, Shu P, Peng X, Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy. Signal Transduct Target Ther. 2024 Feb 14;9(1):32 |
1 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1 | J:165547 Huang T, Krimm RF, Developmental expression of Bdnf, Ntf4/5, and TrkB in the mouse peripheral taste system. Dev Dyn. 2010 Oct;239(10):2637-46 |
2* | J:32951 Klein R, Martin-Zanca D, Barbacid M, Parada LF, Expression of the tyrosine kinase receptor gene trkB is confined to the murine embryonic and adult nervous system. Development. 1990 Aug;109(4):845-50 |
1 | J:77764 Levanon D, Bettoun D, Harris-Cerruti C, Woolf E, Negreanu V, Eilam R, Bernstein Y, Goldenberg D, Xiao C, Fliegauf M, Kremer E, Otto F, Brenner O, Lev-Tov A, Groner Y, The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons. EMBO J. 2002 Jul 1;21(13):3454-63 |
1 | J:37118 McEvilly RJ, Erkman L, Luo L, Sawchenko PE, Ryan AF, Rosenfeld MG, Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature. 1996 Dec 12;384(6609):574-7 |
1 | J:231738 Reed-Geaghan EG, Wright MC, See LA, Adelman PC, Lee KH, Koerber HR, Maricich SM, Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. J Neurosci. 2016 Apr 13;36(15):4362-76 |
1 | J:331367 Roussel J, Larcher R, Sicard P, Bideaux P, Richard S, Marmigere F, Thireau J, The autism-associated Meis2 gene is necessary for cardiac baroreflex regulation in mice. Sci Rep. 2022 Nov 23;12(1):20150 |
1 | J:171905 Scott A, Hasegawa H, Sakurai K, Yaron A, Cobb J, Wang F, Transcription factor short stature homeobox 2 is required for proper development of tropomyosin-related kinase B-expressing mechanosensory neurons. J Neurosci. 2011 May 4;31(18):6741-9 |
2* | J:85731 Spears N, Molinek MD, Robinson LL, Fulton N, Cameron H, Shimoda K, Telfer EE, Anderson RA, Price DJ, The role of neurotrophin receptors in female germ-cell survival in mouse and human. Development. 2003 Nov;130(22):5481-91 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
1 | J:238868 Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z, The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 2016 Aug 02;16(5):1431-44 |
Ntrk3 neurotrophic tyrosine kinase, receptor, type 3 (Synonyms: TrkC) | |
Results | Reference |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1* | J:104896 Cho JH, Tsai MJ, Preferential posterior cerebellum defect in BETA2/NeuroD1 knockout mice is the result of differential expression of BETA2/NeuroD1 along anterior-posterior axis. Dev Biol. 2006 Feb 1;290(1):125-38 |
1 | J:77445 Cronk KM, Wilkinson GA, Grimes R, Wheeler EF, Jhaveri S, Fundin BT, Silos-Santiago I, Tessarollo L, Reichardt LF, Rice FL, Diverse dependencies of developing Merkel innervation on the trkA and both full-length and truncated isoforms of trkC. Development. 2002 Aug;129(15):3739-50 |
1 | J:353354 Desiderio S, Schwaller F, Tartour K, Padmanabhan K, Lewin GR, Carroll P, Marmigere F, Touch receptor end-organ innervation and function require sensory neuron expression of the transcription factor Meis2. Elife. 2024 Feb 22;12 |
1 | J:283226 Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld KA, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ, Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA. Cell Rep. 2019 Mar 26;26(13):3522-3536.e5 |
1 | J:345844 Guo Y, Xiang P, Sun X, Liu W, Zhou J, Yin B, Hou L, Qiang B, Li H, Shu P, Peng X, Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy. Signal Transduct Target Ther. 2024 Feb 14;9(1):32 |
1 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
1 | J:275123 Jenkins BA, Fontecilla NM, Lu CP, Fuchs E, Lumpkin EA, The cellular basis of mechanosensory Merkel-cell innervation during development. Elife. 2019 Feb 22;8:e42633 |
1 | J:37118 McEvilly RJ, Erkman L, Luo L, Sawchenko PE, Ryan AF, Rosenfeld MG, Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature. 1996 Dec 12;384(6609):574-7 |
1 | J:201759 Pan Y, Zhang J, Liu W, Shu P, Yin B, Yuan J, Qiang B, Peng X, Dok5 is involved in the signaling pathway of neurotrophin-3 against TrkC-induced apoptosis. Neurosci Lett. 2013 Oct 11;553:46-51 |
1 | J:149553 Pecho-Vrieseling E, Sigrist M, Yoshida Y, Jessell TM, Arber S, Specificity of sensory-motor connections encoded by Sema3e-Plxnd1 recognition. Nature. 2009 Jun 11;459(7248):842-6 |
1 | J:231738 Reed-Geaghan EG, Wright MC, See LA, Adelman PC, Lee KH, Koerber HR, Maricich SM, Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. J Neurosci. 2016 Apr 13;36(15):4362-76 |
1 | J:331367 Roussel J, Larcher R, Sicard P, Bideaux P, Richard S, Marmigere F, Thireau J, The autism-associated Meis2 gene is necessary for cardiac baroreflex regulation in mice. Sci Rep. 2022 Nov 23;12(1):20150 |
1 | J:171905 Scott A, Hasegawa H, Sakurai K, Yaron A, Cobb J, Wang F, Transcription factor short stature homeobox 2 is required for proper development of tropomyosin-related kinase B-expressing mechanosensory neurons. J Neurosci. 2011 May 4;31(18):6741-9 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
1 | J:86789 Szeder V, Grim M, Kucera J, Sieber-Blum M, Neurotrophin-3 signaling in mammalian Merkel cell development. Dev Dyn. 2003 Dec;228(4):623-9 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Nts neurotensin (Synonyms: 5033428E16Rik, neuromedin N, NMN-125, NT/N, NTS1) | |
Results | Reference |
1 | J:51888 Bulfone A, Wang F, Hevner R, Anderson S, Cutforth T, Chen S, Meneses J, Pedersen R, Axel R, Rubenstein JL, An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons. Neuron. 1998 Dec;21(6):1273-82 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Ntsr1 neurotensin receptor 1 (Synonyms: NT-1R, NTR-1, NTR1, Ntsr1) | |
Results | Reference |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Ntsr2 neurotensin receptor 2 (Synonyms: NT2R, NTRL) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Nuak1 NUAK family, SNF1-like kinase, 1 (Synonyms: B230104P22Rik) | |
Results | Reference |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
2* | J:312812 Fan C, Wu Q, Ye X, Luo H, Yan D, Xiong Y, Zhu H, Diao Y, Zhang W, Wan J, Role of miR-211 in Neuronal Differentiation and Viability: Implications to Pathogenesis of Alzheimer's Disease. Front Aging Neurosci. 2016;8:166 |
Nuak2 NUAK family, SNF1-like kinase, 2 (Synonyms: 1200013B22Rik, mKIAA0537, Snark) | |
Results | Reference |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
Nucks1 nuclear casein kinase and cyclin-dependent kinase substrate 1 (Synonyms: 2700010L10Rik, 8430423A01Rik, Nucks) | |
Results | Reference |
1 | J:206225 Drosos Y, Kouloukoussa M, Ostvold AC, Havaki S, Katsantoni E, Marinos E, Aleporou-Marinou V, Dynamic expression of the vertebrate-specific protein Nucks during rodent embryonic development. Gene Expr Patterns. 2014 Jan;14(1):19-29 |
Nudcd3 NudC domain containing 3 (Synonyms: mKIAA1068) | |
Results | Reference |
1 | J:331893 Yang J, Zhang L, Li Y, Chen M, Identifying key m(6)A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses. Front Genet. 2022;13:974357 |
Numa1 nuclear mitotic apparatus protein 1 (Synonyms: 6720401E04Rik, NuMA) | |
Results | Reference |
1 | J:214812 Chaffee BR, Shang F, Chang ML, Clement TM, Eddy EM, Wagner BD, Nakahara M, Nagata S, Robinson ML, Taylor A, Nuclear removal during terminal lens fiber cell differentiation requires CDK1 activity: appropriating mitosis-related nuclear disassembly. Development. 2014 Sep;141(17):3388-98 |
1 | J:277726 Lecland N, Hsu CY, Chemin C, Merdes A, Bierkamp C, Epidermal development requires ninein for spindle orientation and cortical microtubule organization. Life Sci Alliance. 2019 Apr;2(2) |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Numb NUMB endocytic adaptor protein (Synonyms: m-numb) | |
Results | Reference |
1 | J:193056 Kechad A, Jolicoeur C, Tufford A, Mattar P, Chow RW, Harris WA, Cayouette M, Numb is required for the production of terminal asymmetric cell divisions in the developing mouse retina. J Neurosci. 2012 Nov 28;32(48):17197-210 |
1* | J:310316 Li H, Ramachandran A, Gao Q, Ravindran S, Song Y, Evans C, George A, Expression and function of NUMB in odontogenesis. Biomed Res Int. 2013;2013:182965 |
1 | J:182904 Moran TB, Goldberg LB, Serviss SL, Raetzman LT, Numb deletion in POMC-expressing cells impairs pituitary intermediate lobe cell adhesion, progenitor cell localization, and neuro-intermediate lobe boundary formation. Mol Endocrinol. 2011 Jan;25(1):117-27 |
3 | J:124218 Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan YN, Rakic P, Sestan N, Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci. 2007 Jul;10(7):819-27 |
1 | J:191793 Schnatwinkel C, Niswander L, Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice. PLoS One. 2012;7(9):e44871 |
Numbl numb-like (Synonyms: nbl) | |
Results | Reference |
1 | J:124218 Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan YN, Rakic P, Sestan N, Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci. 2007 Jul;10(7):819-27 |
Nupr1 nuclear protein transcription regulator 1 (Synonyms: 2310032H04Rik, Com1, p8) | |
Results | Reference |
1 | J:140899 Million Passe CM, White CR, King MW, Quirk PL, Iovanna JL, Quirk CC, Loss of the protein NUPR1 (p8) leads to delayed LHB expression, delayed ovarian maturation, and testicular development of a sertoli-cell-only syndrome-like phenotype in mice. Biol Reprod. 2008 Oct;79(4):598-607 |
1 | J:81212 Quirk CC, Seachrist DD, Nilson JH, Embryonic Expression of the Luteinizing Hormone beta Gene Appears to Be Coupled to the Transient Appearance of p8, a High Mobility Group-related Transcription Factor. J Biol Chem. 2003 Jan 17;278(3):1680-5 |
Nusap1 nucleolar and spindle associated protein 1 (Synonyms: 2610201A12Rik, NuSAP) | |
Results | Reference |
2 | J:290729 Grundl M, Walz S, Hauf L, Schwab M, Werner KM, Spahr S, Schulte C, Maric HM, Ade CP, Gaubatz S, Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes. PLoS Genet. 2020 May;16(5):e1008818 |
1* | J:164315 Vanden Bosch A, Raemaekers T, Denayer S, Torrekens S, Smets N, Moermans K, Dewerchin M, Carmeliet P, Carmeliet G, NuSAP is essential for chromatin-induced spindle formation during early embryogenesis. J Cell Sci. 2010 Oct 1;123(Pt 19):3244-55 |
Nwd1 NACHT and WD repeat domain containing 1 (Synonyms: A230063L24Rik) | |
Results | Reference |
1* | J:266346 Yamada S, Sakakibara SI, Expression profile of the STAND protein Nwd1 in the developing and mature mouse central nervous system. J Comp Neurol. 2018 Sep 1;526(13):2099-2114 |
Nwd2 NACHT and WD repeat domain containing 2 (Synonyms: 3110047P20Rik, B830017A01Rik, mKIAA1239) | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1* | J:331484 Yamada S, Furukawa R, Sakakibara SI, Identification and expression profile of novel STAND gene Nwd2 in the mouse central nervous system. Gene Expr Patterns. 2022 Dec;46:119284 |
Nyap1 neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1 (Synonyms: 6430598A04Rik, Nyap1) | |
Results | Reference |
1 | J:180006 Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T, NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54 |
Nyap2 neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2 (Synonyms: 9430031J16Rik, Jr6) | |
Results | Reference |
1 | J:180006 Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T, NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54 |
Oard1 O-acyl-ADP-ribose deacylase 1 (Synonyms: AI314976) | |
Results | Reference |
1 | J:266603 Ito H, Morishita R, Mizuno M, Kawamura N, Tabata H, Nagata KI, Biochemical and Morphological Characterization of a Neurodevelopmental Disorder-Related Mono-ADP-Ribosylhydrolase, MACRO Domain Containing 2. Dev Neurosci. 2018;40(3):278-287 |
Oat ornithine aminotransferase (Synonyms: rhg) | |
Results | Reference |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
Oaz1 ornithine decarboxylase antizyme 1 (Synonyms: Antizyme, antizyme 1, AZ-1, AZ1) | |
Results | Reference |
1 | J:229060 Franzoni E, Booker SA, Parthasarathy S, Rehfeld F, Grosser S, Srivatsa S, Fuchs HR, Tarabykin V, Vida I, Wulczyn FG, miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6. Elife. 2015;4 |
2* | J:67807 Gritli-Linde A, Nilsson J, Bohlooly-Y M, Heby O, Linde A, Nuclear translocation of antizyme and expression of ornithine decarboxylase and antizyme are developmentally regulated. Dev Dyn. 2001 Mar;220(3):259-75 |
Oc90 otoconin 90 (Synonyms: Ocn-95, PLA2L, Pla2ll) | |
Results | Reference |
1 | J:355958 Hartman BH, Durruthy-Durruthy R, Laske RD, Losorelli S, Heller S, Identification and characterization of mouse otic sensory lineage genes. Front Cell Neurosci. 2015;9:79 |
2* | J:82639 Hurle B, Ignatova E, Massironi SM, Mashimo T, Rios X, Thalmann I, Thalmann R, Ornitz DM, Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1. Hum Mol Genet. 2003 Apr 1;12(7):777-89 |
3 | J:91468 Ignatova EG, Thalmann I, Xu B, Ornitz DM, Thalmann R, Molecular mechanisms underlying ectopic otoconia-like particles in the endolymphatic sac of embryonic mice. Hear Res. 2004 Aug;194(1-2):65-72 |
Ociad2 OCIA domain containing 2 (Synonyms: 1810027I20Rik) | |
Results | Reference |
1 | J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356 |
Ocln occludin (Synonyms: Ocl) | |
Results | Reference |
1 | J:56810 Cyr DG, Hermo L, Egenberger N, Mertineit C, Trasler JM, Laird DW, Cellular immunolocalization of occludin during embryonic and postnatal development of the mouse testis and epididymis. Endocrinology. 1999 Aug;140(8):3815-25 |
1 | J:321161 Gerner L, Youssef G, O'Shaughnessy RF, The protein phosphatase 2A regulatory subunit Ppp2r2a is required for Connexin-43 dephosphorlyation during epidermal barrier acquisition. Exp Dermatol. 2013 Nov;22(11):754-6 |
1* | J:93085 Hashizume A, Ueno T, Furuse M, Tsukita S, Nakanishi Y, Hieda Y, Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn. 2004 Oct;231(2):425-31 |
1 | J:167016 Kobayashi K, Yasui M, Cellular and subcellular localization of aquaporins 1, 3, 8, and 9 in amniotic membranes during pregnancy in mice. Cell Tissue Res. 2010 Nov;342(2):307-16 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1* | J:107229 Ohta H, Adachi H, Inaba M, Developmental changes in the expression of tight junction protein claudins in murine metanephroi and embryonic kidneys. J Vet Med Sci. 2006 Feb;68(2):149-55 |
1 | J:199582 Youssef G, Gerner L, Naeem AS, Ralph O, Ono M, O'Neill CA, O'Shaughnessy RF, Rab3Gap1 mediates exocytosis of Claudin-1 and tight junction formation during epidermal barrier acquisition. Dev Biol. 2013 Aug 15;380(2):274-85 |
1 | J:125580 Zhang L, Deng M, Kao CW, Kao WW, Xia Y, MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis. Mol Vis. 2003 Nov 3;9:584-93 |
Ocm oncomodulin | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1 | J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12) |
Ocrl OCRL, inositol polyphosphate-5-phosphatase (Synonyms: 9530014D17Rik, OCRL1, oculocerebrorenal syndrome of Lowe) | |
Results | Reference |
1* | J:47884 Janne PA, Suchy SF, Bernard D, MacDonald M, Crawley J, Grinberg A , Wynshaw-Boris A , Westphal H , Nussbaum RL, Functional overlap between murine Inpp5b and Ocrl1 may explain why deficiency of the murine ortholog for OCRL1 does not cause Lowe syndrome in mice. J Clin Invest. 1998 May 15;101(10):2042-53 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
Odc1 ornithine decarboxylase, structural 1 (Synonyms: ODC) | |
Results | Reference |
2* | J:67807 Gritli-Linde A, Nilsson J, Bohlooly-Y M, Heby O, Linde A, Nuclear translocation of antizyme and expression of ornithine decarboxylase and antizyme are developmentally regulated. Dev Dyn. 2001 Mar;220(3):259-75 |
1 | J:160518 Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, Jenkins RB, Tihan T, Vandenberg SR, James CD, Tanaka K, Taylor MD, Weiss WA, Chesler L, Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010 May 15;24(10):1059-72 |
Odf2 outer dense fiber of sperm tails 2 (Synonyms: cenexin, MMTEST29) | |
Results | Reference |
1* | J:183945 Carlisle FA, Steel KP, Lewis MA, Specific expression of Kcna10, Pxn and Odf2 in the organ of Corti. Gene Expr Patterns. 2012 May;12(5-6):172-9 |
Ofd1 OFD1, centriole and centriolar satellite protein (Synonyms: DXGgc7e, oral-facial-digital syndrome 1 gene homolog (human), ORF2) | |
Results | Reference |
1* | J:168038 Bimonte S, De Angelis A, Quagliata L, Giusti F, Tammaro R, Dallai R, Ascenzi MG, Diez-Roux G, Franco B, Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol. 2011 Jan 15;349(2):179-91 |
1* | J:67844 Ferrante MI, Giorgio G, Feather SA, Bulfone A, Wright V, Ghiani M, Selicorni A, Gammaro L, Scolari F, Woolf AS, Sylvie O, Bernard L, Malcolm S, Winter R, Ballabio A, Franco B, Identification of the gene for oral-facial-digital type I syndrome. Am J Hum Genet. 2001 Mar;68(3):569-76 |
Ogdh oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) (Synonyms: 2210403E04Rik, 2210412K19Rik, alpha-ketoglutarate dehydrogenase, d1401) | |
Results | Reference |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
Ogn osteoglycin (Synonyms: 3110079A16Rik, mimecan, mimican, OG, SLRR3A) | |
Results | Reference |
1 | J:91136 Tasheva ES, Ke A, Deng Y, Jun C, Takemoto LJ, Koester A, Conrad GW, Differentially expressed genes in the lens of mimecan-null mice. Mol Vis. 2004 Jun 17;10:403-16 |
Ogt O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase) (Synonyms: 1110038P24Rik, 4831420N21Rik, OGT, Ogtl) | |
Results | Reference |
1 | J:288301 Mu Y, Yu H, Wu T, Zhang J, Evans SM, Chen J, O-linked beta-N-acetylglucosamine transferase plays an essential role in heart development through regulating angiopoietin-1. PLoS Genet. 2020 Apr;16(4):e1008730 |
2* | J:358134 Soma S, Murakami K, Fukuchi Y, Kunimoto H, Nakajima H, O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. Stem Cells. 2024 Jan 13;42(1):55-63 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Olfm1 olfactomedin 1 (Synonyms: Noelin 1, Noelin 2, Pancortin 1-4) | |
Results | Reference |
2 | J:104246 Ando K, Nagano T, Nakamura A, Konno D, Yagi H, Sato M, Expression and characterization of disulfide bond use of oligomerized A2-Pancortins: extracellular matrix constituents in the developing brain. Neuroscience. 2005;133(4):947-57 |
2* | J:62796 Nagano T, Nakamura A, Konno D, Kurata M, Yagi H, Sato M, A2-Pancortins (Pancortin-3 and -4) are the dominant pancortins during neocortical development. J Neurochem. 2000 Jul;75(1):1-8 |
1* | J:171532 Sultana A, Nakaya N, Senatorov VV, Tomarev SI, Olfactomedin 2: expression in the eye and interaction with other olfactomedin domain-containing proteins. Invest Ophthalmol Vis Sci. 2011 Apr;52(5):2584-92 |
Olfm2 olfactomedin 2 (Synonyms: A030009A06Rik) | |
Results | Reference |
1* | J:171532 Sultana A, Nakaya N, Senatorov VV, Tomarev SI, Olfactomedin 2: expression in the eye and interaction with other olfactomedin domain-containing proteins. Invest Ophthalmol Vis Sci. 2011 Apr;52(5):2584-92 |
Olfm3 olfactomedin 3 (Synonyms: B230206G02Rik, optimedin) | |
Results | Reference |
1* | J:171532 Sultana A, Nakaya N, Senatorov VV, Tomarev SI, Olfactomedin 2: expression in the eye and interaction with other olfactomedin domain-containing proteins. Invest Ophthalmol Vis Sci. 2011 Apr;52(5):2584-92 |
Olfm4 olfactomedin 4 (Synonyms: GC1, GW112, LOC239192, LOC380924, OlfD, pPD4) | |
Results | Reference |
2* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
Olig1 oligodendrocyte transcription factor 1 (Synonyms: Bhlhb6, bHLHe21, Olg-1) | |
Results | Reference |
1 | J:212081 Dai ZM, Sun S, Wang C, Huang H, Hu X, Zhang Z, Lu QR, Qiu M, Stage-specific regulation of oligodendrocyte development by Wnt/beta-catenin signaling. J Neurosci. 2014 Jun 18;34(25):8467-73 |
1* | J:224559 Kanaya E, Yamahara K, Okano T, Yoshida A, Katsuno T, Takebayashi H, Ito J, Yamamoto N, Expression of the Olig gene family in the developing mouse inner ear. Gene Expr Patterns. 2015 Mar;17(2):79-86 |
1 | J:300967 Pajovic S, Siddaway R, Bridge T, Sheth J, Rakopoulos P, Kim B, Ryall S, Agnihotri S, Phillips L, Yu M, Li C, Milos S, Patel P, Srikanthan D, Huang A, Hawkins C, Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer. Nat Commun. 2020 Dec 4;11(1):6216 |
1 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1* | J:73068 Spassky N, Heydon K, Mangatal A, Jankovski A, Olivier C, Queraud-Lesaux F, Goujet-Zalc C, Thomas JL, Zalc B, Sonic hedgehog-dependent emergence of oligodendrocytes in the telencephalon: evidence for a source of oligodendrocytes in the olfactory bulb that is independent of PDGFRalpha signaling. Development. 2001 Dec;128(24):4993-5004 |
Olig2 oligodendrocyte transcription factor 2 (Synonyms: Bhlhb1, bHLHe19, Olg-2, RK17) | |
Results | Reference |
1* | J:130196 Alfonsi F, Filippi P, Salaun D, deLapeyriere O, Durbec P, LIFR beta plays a major role in neuronal identity determination and glial differentiation in the mouse facial nucleus. Dev Biol. 2008 Jan 1;313(1):267-78 |
1* | J:189472 Armendariz BG, Bribian A, Perez-Martinez E, Martinez A, de Castro F, Soriano E, Burgaya F, Expression of Semaphorin 4F in neurons and brain oligodendrocytes and the regulation of oligodendrocyte precursor migration in the optic nerve. Mol Cell Neurosci. 2012 Jan;49(1):54-67 |
1 | J:336863 Barry-Carroll L, Greulich P, Marshall AR, Riecken K, Fehse B, Askew KE, Li K, Garaschuk O, Menassa DA, Gomez-Nicola D, Microglia colonize the developing brain by clonal expansion of highly proliferative progenitors, following allometric scaling. Cell Rep. 2023 May 30;42(5):112425 |
1 | J:218900 Bischof M, Weider M, Kuspert M, Nave KA, Wegner M, Brg1-dependent chromatin remodelling is not essentially required during oligodendroglial differentiation. J Neurosci. 2015 Jan 7;35(1):21-35 |
2 | J:187211 Bribian A, Fontana X, Llorens F, Gavin R, Reina M, Garcia-Verdugo JM, Torres JM, de Castro F, del Rio JA, Role of the cellular prion protein in oligodendrocyte precursor cell proliferation and differentiation in the developing and adult mouse CNS. PLoS One. 2012;7(4):e33872 |
1 | J:265822 Chapman H, Riesenberg A, Ehrman LA, Kohli V, Nardini D, Nakafuku M, Campbell K, Waclaw RR, Gsx transcription factors control neuronal versus glial specification in ventricular zone progenitors of the mouse lateral ganglionic eminence. Dev Biol. 2018 Oct 1;442(1):115-126 |
1 | J:190166 Chen JA, Wichterle H, Apoptosis of limb innervating motor neurons and erosion of motor pool identity upon lineage specific dicer inactivation. Front Neurosci. 2012;6:69 |
1 | J:217413 Choe Y, Huynh T, Pleasure SJ, Migration of oligodendrocyte progenitor cells is controlled by transforming growth factor beta family proteins during corticogenesis. J Neurosci. 2014 Nov 5;34(45):14973-83 |
1 | J:126065 Costa MR, Kessaris N, Richardson WD, Gotz M, Hedin-Pereira C, The marginal zone/layer I as a novel niche for neurogenesis and gliogenesis in developing cerebral cortex. J Neurosci. 2007 Oct 17;27(42):11376-88 |
1 | J:212081 Dai ZM, Sun S, Wang C, Huang H, Hu X, Zhang Z, Lu QR, Qiu M, Stage-specific regulation of oligodendrocyte development by Wnt/beta-catenin signaling. J Neurosci. 2014 Jun 18;34(25):8467-73 |
1 | J:213791 Dutta DJ, Zameer A, Mariani JN, Zhang J, Asp L, Huynh J, Mahase S, Laitman BM, Argaw AT, Mitiku N, Urbanski M, Melendez-Vasquez CV, Casaccia P, Hayot F, Bottinger EP, Brown CW, John GR, Combinatorial actions of Tgfbeta and Activin ligands promote oligodendrocyte development and CNS myelination. Development. 2014 Jun;141(12):2414-28 |
1* | J:74236 Fu H, Qi Y, Tan M, Cai J, Takebayashi H, Nakafuku M, Richardson W, Qiu M, Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation. Development. 2002 Feb;129(3):681-93 |
1 | J:171201 Furusho M, Kaga Y, Ishii A, Hebert JM, Bansal R, Fibroblast growth factor signaling is required for the generation of oligodendrocyte progenitors from the embryonic forebrain. J Neurosci. 2011 Mar 30;31(13):5055-66 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:184797 Hafler BP, Surzenko N, Beier KT, Punzo C, Trimarchi JM, Kong JH, Cepko CL, Transcription factor Olig2 defines subpopulations of retinal progenitor cells biased toward specific cell fates. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7882-7 |
1 | J:293063 Hamashima T, Ishii Y, Nguyen LQ, Okuno N, Sang Y, Matsushima T, Kurashige Y, Takebayashi H, Mori H, Fujimori T, Yamamoto S, Sasahara M, Oligodendrogenesis and Myelin Formation in the Forebrain Require Platelet-derived Growth Factor Receptor-alpha. Neuroscience. 2020 Jun 1;436:11-26 |
1* | J:231833 Hashimoto R, Hori K, Owa T, Miyashita S, Dewa K, Masuyama N, Sakai K, Hayase Y, Seto Y, Inoue YU, Inoue T, Ichinohe N, Kawaguchi Y, Akiyama H, Koizumi S, Hoshino M, Origins of oligodendrocytes in the cerebellum, whose development is controlled by the transcription factor, Sox9. Mech Dev. 2016 May;140:25-40 |
1 | J:162581 Huillard E, Ziercher L, Blond O, Wong M, Deloulme JC, Souchelnytskyi S, Baudier J, Cochet C, Buchou T, Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalon. Mol Cell Biol. 2010 Jun;30(11):2737-49 |
1* | J:224559 Kanaya E, Yamahara K, Okano T, Yoshida A, Katsuno T, Takebayashi H, Ito J, Yamamoto N, Expression of the Olig gene family in the developing mouse inner ear. Gene Expr Patterns. 2015 Mar;17(2):79-86 |
1 | J:235955 Laitman BM, Asp L, Mariani JN, Zhang J, Liu J, Sawai S, Chapouly C, Horng S, Kramer EG, Mitiku N, Loo H, Burlant N, Pedre X, Hara Y, Nudelman G, Zaslavsky E, Lee YM, Braun DA, Lu QR, Narla G, Raine CS, Friedman SL, Casaccia P, John GR, The Transcriptional Activator Kruppel-like Factor-6 Is Required for CNS Myelination. PLoS Biol. 2016 May;14(5):e1002467 |
1 | J:107096 Le Bras B, Barallobre MJ, Homman-Ludiye J, Ny A, Wyns S, Tammela T, Haiko P, Karkkainen MJ, Yuan L, Muriel MP, Chatzopoulou E, Breant C, Zalc B, Carmeliet P, Alitalo K, Eichmann A, Thomas JL, VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain. Nat Neurosci. 2006 Mar;9(3):340-8 |
1 | J:194149 Le Bras B, Chatzopoulou E, Heydon K, Martinez S, Ikenaka K, Prestoz L, Spassky N, Zalc B, Thomas JL, Oligodendrocyte development in the embryonic brain: the contribution of the plp lineage. Int J Dev Biol. 2005;49(2-3):209-20 |
1 | J:263715 Lee B, Kim J, An T, Kim S, Patel EM, Raber J, Lee SK, Lee S, Lee JW, Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons. Nat Commun. 2018 May 23;9(1):2026 |
1 | J:348857 Li Z, Liu G, Yang L, Sun M, Zhang Z, Xu Z, Gao Y, Jiang X, Su Z, Li X, Yang Z, BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period. Protein Cell. 2024 Jan 3;15(1):21-35 |
1 | J:348287 Liang XG, Hoang K, Meyerink BL, Kc P, Paraiso K, Wang L, Jones IR, Zhang Y, Katzman S, Finn TS, Tsyporin J, Qu F, Chen Z, Visel A, Kriegstein A, Shen Y, Pilaz LJ, Chen B, A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex. Proc Natl Acad Sci U S A. 2024 May 14;121(20):e2321711121 |
1 | J:275488 Lim Y, Cho IT, Shi X, Grinspan JB, Cho G, Golden JA, Arx Expression Suppresses Ventralization of the Developing Dorsal Forebrain. Sci Rep. 2019 Jan 18;9(1):226 |
1 | J:177840 Magri L, Cambiaghi M, Cominelli M, Alfaro-Cervello C, Cursi M, Pala M, Bulfone A, Garcia-Verdugo JM, Leocani L, Minicucci F, Poliani PL, Galli R, Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions. Cell Stem Cell. 2011 Nov 4;9(5):447-62 |
1 | J:252094 Matuzelski E, Bunt J, Harkins D, Lim JWC, Gronostajski RM, Richards LJ, Harris L, Piper M, Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord. Dev Biol. 2017 Dec 15;432(2):286-297 |
1 | J:269506 Minocha S, Valloton D, Brunet I, Eichmann A, Hornung JP, Lebrand C, NG2 glia are required for vessel network formation during embryonic development. Elife. 2015 Dec 10;4:e09102 |
1 | J:123317 Miyoshi G, Butt SJ, Takebayashi H, Fishell G, Physiologically distinct temporal cohorts of cortical interneurons arise from telencephalic Olig2-expressing precursors. J Neurosci. 2007 Jul 18;27(29):7786-98 |
1 | J:277848 Ohayon D, Escalas N, Cochard P, Glise B, Danesin C, Soula C, Sulfatase 2 promotes generation of a spinal cord astrocyte subtype that stands out through the expression of Olig2. Glia. 2019 Aug;67(8):1478-1495 |
1 | J:242339 Ohayon D, Garces A, Joly W, Soukkarieh C, Takagi T, Sabourin JC, Agius E, Darling DS, De Santa Barbara P, Higashi Y, Stolt CC, Hugnot JP, Richardson WD, Carroll P, Pattyn A, Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Cell Rep. 2016 Nov 01;17(6):1473-1481 |
3 | J:187102 Ortega MC, Bribian A, Peregrin S, Gil MT, Marin O, de Castro F, Neuregulin-1/ErbB4 signaling controls the migration of oligodendrocyte precursor cells during development. Exp Neurol. 2012 Jun;235(2):610-20 |
1 | J:300967 Pajovic S, Siddaway R, Bridge T, Sheth J, Rakopoulos P, Kim B, Ryall S, Agnihotri S, Phillips L, Yu M, Li C, Milos S, Patel P, Srikanthan D, Huang A, Hawkins C, Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer. Nat Commun. 2020 Dec 4;11(1):6216 |
1 | J:305247 Paredes I, Vieira JR, Shah B, Ramunno CF, Dyckow J, Adler H, Richter M, Schermann G, Giannakouri E, Schirmer L, Augustin HG, Ruiz de Almodovar C, Oligodendrocyte precursor cell specification is regulated by bidirectional neural progenitor-endothelial cell crosstalk. Nat Neurosci. 2021 Apr;24(4):478-488 |
1 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1* | J:84432 Qi Y, Tan M, Hui CC, Qiu M, Gli2 is required for normal Shh signaling and oligodendrocyte development in the spinal cord. Mol Cell Neurosci. 2003 Jul;23(3):440-50 |
1 | J:192558 Rabe TI, Griesel G, Blanke S, Kispert A, Leitges M, van der Zwaag B, Burbach JP, Varoqueaux F, Mansouri A, The transcription factor Uncx4.1 acts in a short window of midbrain dopaminergic neuron differentiation. Neural Dev. 2012;7:39 |
1* | J:210661 Seto Y, Ishiwata S, Hoshino M, Characterization of Olig2 expression during cerebellar development. Gene Expr Patterns. 2014 May;15(1):1-7 |
1 | J:270726 Shimada IS, Hwang SH, Somatilaka BN, Wang X, Skowron P, Kim J, Kim M, Shelton JM, Rajaram V, Xuan Z, Taylor MD, Mukhopadhyay S, Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis. Cell Rep. 2018 Jan 30;22(5):1169-1184 |
1* | J:73068 Spassky N, Heydon K, Mangatal A, Jankovski A, Olivier C, Queraud-Lesaux F, Goujet-Zalc C, Thomas JL, Zalc B, Sonic hedgehog-dependent emergence of oligodendrocytes in the telencephalon: evidence for a source of oligodendrocytes in the olfactory bulb that is independent of PDGFRalpha signaling. Development. 2001 Dec;128(24):4993-5004 |
1 | J:98431 Stolt CC, Lommes P, Friedrich RP, Wegner M, Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy. Development. 2004 May;131(10):2349-58 |
1 | J:84301 Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M, The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 2003 Jul 1;17(13):1677-89 |
1 | J:74258 Stolt CC, Rehberg S, Ader M, Lommes P, Riethmacher D, Schachner M, Bartsch U, Wegner M, Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev. 2002 Jan 15;16(2):165-70 |
1 | J:116148 Stolt CC, Schlierf A, Lommes P, Hillgartner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M, SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell. 2006 Nov;11(5):697-709 |
2* | J:98585 Stolt CC, Schmitt S, Lommes P, Sock E, Wegner M, Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord. Dev Biol. 2005 May 15;281(2):309-17 |
1 | J:135133 Sugimori M, Nagao M, Bertrand N, Parras CM, Guillemot F, Nakafuku M, Combinatorial actions of patterning and HLH transcription factors in the spatiotemporal control of neurogenesis and gliogenesis in the developing spinal cord. Development. 2007 Apr;134(8):1617-29 |
1 | J:135661 Sugimori M, Nagao M, Parras CM, Nakatani H, Lebel M, Guillemot F, Nakafuku M, Ascl1 is required for oligodendrocyte development in the spinal cord. Development. 2008 Apr;135(7):1271-81 |
1 | J:354182 Sun M, Gao Y, Li Z, Yang L, Liu G, Xu Z, Guo R, You Y, Yang Z, ERK signaling expands mammalian cortical radial glial cells and extends the neurogenic period. Proc Natl Acad Sci U S A. 2024 Mar 26;121(13):e2314802121 |
1 | J:162846 Teissier A, Griveau A, Vigier L, Piolot T, Borello U, Pierani A, A novel transient glutamatergic population migrating from the pallial-subpallial boundary contributes to neocortical development. J Neurosci. 2010 Aug 4;30(31):10563-74 |
1 | J:193303 Vidaki M, Tivodar S, Doulgeraki K, Tybulewicz V, Kessaris N, Pachnis V, Karagogeos D, Rac1-dependent cell cycle exit of MGE precursors and GABAergic interneuron migration to the cortex. Cereb Cortex. 2012 Mar;22(3):680-92 |
1* | J:337458 Waldhauser V, Baroti T, Frob F, Wegner M, PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12) |
1* | J:288669 Wedel M, Frob F, Elsesser O, Wittmann MT, Lie DC, Reis A, Wegner M, Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation. Nucleic Acids Res. 2020 May 21;48(9):4839-4857 |
1 | J:305176 Wei Y, Han X, Zhao C, PDK1 regulates the survival of the developing cortical interneurons. Mol Brain. 2020 May 4;13(1):65 |
1 | J:105927 Wu S, Wu Y, Capecchi MR, Motoneurons and oligodendrocytes are sequentially generated from neural stem cells but do not appear to share common lineage-restricted progenitors in vivo. Development. 2006 Feb;133(4):581-90 |
1 | J:359856 Xu X, Fang M, Chen L, Huang H, Dai ZM, Yang J, Qiu M, Nzf2 promotes oligodendrocyte differentiation and regeneration via repressing HDAC1-mediated histone deacetylation. Sci Adv. 2024 Dec 13;10(50):eadf8405 |
1 | J:152576 Ye F, Chen Y, Hoang T, Montgomery RL, Zhao XH, Bu H, Hu T, Taketo MM, van Es JH, Clevers H, Hsieh J, Bassel-Duby R, Olson EN, Lu QR, HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci. 2009 Jul;12(7):829-38 |
1 | J:154660 Zhang Y, Argaw AT, Gurfein BT, Zameer A, Snyder BJ, Ge C, Lu QR, Rowitch DH, Raine CS, Brosnan CF, John GR, Notch1 signaling plays a role in regulating precursor differentiation during CNS remyelination. Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19162-7 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
1 | J:168041 Zhu Y, Park J, Hu X, Zheng K, Li H, Cao Q, Feng GS, Qiu M, Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase. Glia. 2010 Sep;58(12):1407-14 |
Olig3 oligodendrocyte transcription factor 3 (Synonyms: Bhlhb7, bHLHe20) | |
Results | Reference |
1 | J:167212 Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ, Subtypes of medulloblastoma have distinct developmental origins. Nature. 2010 Dec 23;468(7327):1095-9 |
1* | J:224559 Kanaya E, Yamahara K, Okano T, Yoshida A, Katsuno T, Takebayashi H, Ito J, Yamamoto N, Expression of the Olig gene family in the developing mouse inner ear. Gene Expr Patterns. 2015 Mar;17(2):79-86 |
1 | J:132518 Vue TY, Aaker J, Taniguchi A, Kazemzadeh C, Skidmore JM, Martin DM, Martin JF, Treier M, Nakagawa Y, Characterization of progenitor domains in the developing mouse thalamus. J Comp Neurol. 2007 Nov 1;505(1):73-91 |
Olr1 oxidized low density lipoprotein (lectin-like) receptor 1 (Synonyms: LOX-1, Scare1, SR-EI) | |
Results | Reference |
1* | J:141691 Satoh H, Kiyota E, Terasaki Y, Sawamura T, Takagi K, Mizuta H, Takeya M, Expression and localization of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) in murine and human placentas. J Histochem Cytochem. 2008 Aug;56(8):773-84 |
Omp olfactory marker protein | |
Results | Reference |
1 | J:218066 Amaya DA, Wegner M, Stolt CC, Chehrehasa F, Ekberg JA, St John JA, Radial glia phagocytose axonal debris from degenerating overextending axons in the developing olfactory bulb. J Comp Neurol. 2015 Feb 1;523(2):183-96 |
1 | J:102255 Balmer CW, LaMantia AS, Noses and neurons: induction, morphogenesis, and neuronal differentiation in the peripheral olfactory pathway. Dev Dyn. 2005 Nov;234(3):464-81 |
1 | J:109287 Balmer CW, LaMantia AS, Loss of Gli3 and Shh function disrupts olfactory axon trajectories. J Comp Neurol. 2004 May 3;472(3):292-307 |
1* | J:199435 Barraud P, St John JA, Stolt CC, Wegner M, Baker CV, Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Biol Open. 2013 Jul 15;2(7):750-9 |
1 | J:244587 Bastakis GG, Savvaki M, Stamatakis A, Vidaki M, Karagogeos D, Tag1 deficiency results in olfactory dysfunction through impaired migration of mitral cells. Development. 2015 Dec 15;142(24):4318-28 |
1* | J:74091 Camoletto P, Colesanti A, Ozon S, Sobel A, Fasolo A, Expression of stathmin and SCG10 proteins in the olfactory neurogenesis during development and after lesion in the adulthood. Brain Res Bull. 2001 Jan 1;54(1):19-28 |
1* | J:104313 Fuss SH, Omura M, Mombaerts P, The Grueneberg ganglion of the mouse projects axons to glomeruli in the olfactory bulb. Eur J Neurosci. 2005 Nov;22(10):2649-54 |
1 | J:73312 Gong SG, Characterization of olfactory nerve abnormalities in Twirler mice. Differentiation. 2001 Dec;69(1):58-65 |
2* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
1* | J:170495 Ikeda K, Kageyama R, Suzuki Y, Kawakami K, Six1 is indispensable for production of functional progenitor cells during olfactory epithelial development. Int J Dev Biol. 2010;54(10):1453-64 |
1* | J:126356 Ikeda K, Ookawara S, Sato S, Ando Z, Kageyama R, Kawakami K, Six1 is essential for early neurogenesis in the development of olfactory epithelium. Dev Biol. 2007 Nov 1;311(1):53-68 |
1 | J:235517 Kam JW, Dumontier E, Baim C, Brignall AC, Mendes da Silva D, Cowan M, Kennedy TE, Cloutier JF, RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016 May 1;143(9):1534-46 |
1 | J:83383 Levi G, Puche AC, Mantero S, Barbieri O, Trombino S, Paleari L, Egeo A, Merlo GR, The Dlx5 homeodomain gene is essential for olfactory development and connectivity in the mouse. Mol Cell Neurosci. 2003 Apr;22(4):530-43 |
1 | J:316129 Login H, Butowt R, Bohm S, Activity-dependent and graded BACE1 expression in the olfactory epithelium is mediated by the retinoic acid metabolizing enzyme CYP26B1. Brain Struct Funct. 2015 Jul;220(4):2143-57 |
1 | J:237697 Maurya DK, Henriques T, Marini M, Pedemonte N, Galietta LJ, Rock JR, Harfe BD, Menini A, Development of the Olfactory Epithelium and Nasal Glands in TMEM16A-/- and TMEM16A+/+ Mice. PLoS One. 2015;10(6):e0129171 |
1* | J:134543 Nguyen-Ba-Charvet KT, Di Meglio T, Fouquet C, Chedotal A, Robos and slits control the pathfinding and targeting of mouse olfactory sensory axons. J Neurosci. 2008 Apr 16;28(16):4244-9 |
1 | J:162564 Ohsawa S, Hamada S, Kuida K, Yoshida H, Igaki T, Miura M, Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13366-71 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:154741 Prince JE, Cho JH, Dumontier E, Andrews W, Cutforth T, Tessier-Lavigne M, Parnavelas J, Cloutier JF, Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. J Neurosci. 2009 Nov 11;29(45):14211-22 |
1* | J:268254 Rich CA, Perera SN, Andratschke J, Stolt CC, Buehler DP, Southard-Smith EM, Wegner M, Britsch S, Baker CVH, Olfactory ensheathing cells abutting the embryonic olfactory bulb express Frzb, whose deletion disrupts olfactory axon targeting. Glia. 2018 Dec;66(12):2617-2631 |
1 | J:136049 Scolnick JA, Cui K, Duggan CD, Xuan S, Yuan XB, Efstratiadis A, Ngai J, Role of IGF signaling in olfactory sensory map formation and axon guidance. Neuron. 2008 Mar 27;57(6):847-57 |
1 | J:167943 Takeuchi H, Inokuchi K, Aoki M, Suto F, Tsuboi A, Matsuda I, Suzuki M, Aiba A, Serizawa S, Yoshihara Y, Fujisawa H, Sakano H, Sequential arrival and graded secretion of Sema3F by olfactory neuron axons specify map topography at the bulb. Cell. 2010 Jun 11;141(6):1056-67 |
1 | J:163859 Tucker ES, Lehtinen MK, Maynard T, Zirlinger M, Dulac C, Rawson N, Pevny L, Lamantia AS, Proliferative and transcriptional identity of distinct classes of neural precursors in the mammalian olfactory epithelium. Development. 2010 Aug 1;137(15):2471-81 |
1 | J:164874 Wang L, Vervoort V, Wallez Y, Core N, Cremer H, Pasquale EB, The SRC homology 2 domain protein Shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain. J Neurosci. 2010 Sep 29;30(39):13201-10 |
1 | J:174482 Watanabe Y, Inoue K, Okuyama-Yamamoto A, Nakai N, Nakatani J, Nibu K, Sato N, Iiboshi Y, Yusa K, Kondoh G, Takeda J, Terashima T, Takumi T, Fezf1 is required for penetration of the basal lamina by olfactory axons to promote olfactory development. J Comp Neurol. 2009 Aug 10;515(5):565-84 |
Onecut1 one cut domain, family member 1 (Synonyms: D9Ertd423e, Hfh12, Hnf6, HNF6, Oc1, OC-1) | |
Results | Reference |
1 | J:111407 Beaudry JB, Pierreux CE, Hayhurst GP, Plumb-Rudewiez N, Weiss MC, Rousseau GG, Lemaigre FP, Threshold levels of hepatocyte nuclear factor 6 (HNF-6) acting in synergy with HNF-4 and PGC-1alpha are required for time-specific gene expression during liver development. Mol Cell Biol. 2006 Aug;26(16):6037-46 |
1* | J:75933 Clotman F, Lannoy VJ, Reber M, Cereghini S, Cassiman D, Jacquemin P, Roskams T, Rousseau GG, Lemaigre FP, The onecut transcription factor HNF6 is required for normal development of the biliary tract. Development. 2002 Apr;129(8):1819-28 |
2 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1 | J:223559 Goetz JJ, Martin GM, Chowdhury R, Trimarchi JM, Onecut1 and Onecut2 play critical roles in the development of the mouse retina. PLoS One. 2014;9(10):e110194 |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
1 | J:126770 Hodge LK, Klassen MP, Han BX, Yiu G, Hurrell J, Howell A, Rousseau G, Lemaigre F, Tessier-Lavigne M, Wang F, Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps. Neuron. 2007 Aug 16;55(4):572-86 |
1* | J:124126 Hunter MP, Wilson CM, Jiang X, Cong R, Vasavada H, Kaestner KH, Bogue CW, The homeobox gene Hhex is essential for proper hepatoblast differentiation and bile duct morphogenesis. Dev Biol. 2007 Aug 15;308(2):355-67 |
1* | J:85477 Jacquemin P, Pierreux CE, Fierens S, van Eyll JM, Lemaigre FP, Rousseau GG, Cloning and embryonic expression pattern of the mouse Onecut transcription factor OC-2. Gene Expr Patterns. 2003 Oct;3(5):639-44 |
1 | J:154990 Kang HS, Kim YS, ZeRuth G, Beak JY, Gerrish K, Kilic G, Sosa-Pineda B, Jensen J, Foley J, Jetten AM, Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression. Mol Cell Biol. 2009 Dec;29(24):6366-79 |
1 | J:111670 Kyrmizi I, Hatzis P, Katrakili N, Tronche F, Gonzalez FJ, Talianidis I, Plasticity and expanding complexity of the hepatic transcription factor network during liver development. Genes Dev. 2006 Aug 15;20(16):2293-305 |
1 | J:151981 Spence JR, Lange AW, Lin SC, Kaestner KH, Lowy AM, Kim I, Whitsett JA, Wells JM, Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell. 2009 Jul;17(1):62-74 |
1 | J:178995 Stam FJ, Hendricks TJ, Zhang J, Geiman EJ, Francius C, Labosky PA, Clotman F, Goulding M, Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program. Development. 2012 Jan;139(1):179-90 |
2 | J:231427 Vanderpool C, Sparks EE, Huppert KA, Gannon M, Means AL, Huppert SS, Genetic interactions between hepatocyte nuclear factor-6 and Notch signaling regulate mouse intrahepatic bile duct development in vivo. Hepatology. 2012 Jan;55(1):233-43 |
1* | J:183957 Wu F, Sapkota D, Li R, Mu X, Onecut 1 and Onecut 2 are potential regulators of mouse retinal development. J Comp Neurol. 2012 Apr 1;520(5):952-69 |
1* | J:201764 Yamamoto K, Matsuoka TA, Kawashima S, Takebe S, Kubo N, Miyatsuka T, Kaneto H, Shimomura I, A novel function of Onecut1 protein as a negative regulator of MafA gene expression. J Biol Chem. 2013 Jul 26;288(30):21648-58 |
Onecut2 one cut domain, family member 2 (Synonyms: Oc2, OC-2) | |
Results | Reference |
1 | J:223559 Goetz JJ, Martin GM, Chowdhury R, Trimarchi JM, Onecut1 and Onecut2 play critical roles in the development of the mouse retina. PLoS One. 2014;9(10):e110194 |
2 | J:126770 Hodge LK, Klassen MP, Han BX, Yiu G, Hurrell J, Howell A, Rousseau G, Lemaigre F, Tessier-Lavigne M, Wang F, Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps. Neuron. 2007 Aug 16;55(4):572-86 |
1* | J:85477 Jacquemin P, Pierreux CE, Fierens S, van Eyll JM, Lemaigre FP, Rousseau GG, Cloning and embryonic expression pattern of the mouse Onecut transcription factor OC-2. Gene Expr Patterns. 2003 Oct;3(5):639-44 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
2 | J:178995 Stam FJ, Hendricks TJ, Zhang J, Geiman EJ, Francius C, Labosky PA, Clotman F, Goulding M, Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program. Development. 2012 Jan;139(1):179-90 |
1* | J:183957 Wu F, Sapkota D, Li R, Mu X, Onecut 1 and Onecut 2 are potential regulators of mouse retinal development. J Comp Neurol. 2012 Apr 1;520(5):952-69 |
Onecut3 one cut domain, family member 3 (Synonyms: Oc3, OC-3) | |
Results | Reference |
1* | J:85477 Jacquemin P, Pierreux CE, Fierens S, van Eyll JM, Lemaigre FP, Rousseau GG, Cloning and embryonic expression pattern of the mouse Onecut transcription factor OC-2. Gene Expr Patterns. 2003 Oct;3(5):639-44 |
Ooep oocyte expressed protein (Synonyms: 2410146L05Rik, Floped, Moep19) | |
Results | Reference |
2* | J:299510 Wang JJ, Ge W, Zhai QY, Liu JC, Sun XW, Liu WX, Li L, Lei CZ, Dyce PW, De Felici M, Shen W, Single-cell transcriptome landscape of ovarian cells during primordial follicle assembly in mice. PLoS Biol. 2020 Dec;18(12):e3001025 |
Oog1 oogenesin 1 (Synonyms: c-1, Oog) | |
Results | Reference |
1* | J:86145 Minami N, Aizawa A, Ihara R, Miyamoto M, Ohashi A, Imai H, Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos. Biol Reprod. 2003 Nov;69(5):1736-42 |
Opa1 OPA1, mitochondrial dynamin like GTPase (Synonyms: 1200011N24Rik, lilr3, optic atrophy 1) | |
Results | Reference |
1* | J:92284 Aijaz S, Erskine L, Jeffery G, Bhattacharya SS, Votruba M, Developmental expression profile of the optic atrophy gene product: OPA1 is not localized exclusively in the mammalian retinal ganglion cell layer. Invest Ophthalmol Vis Sci. 2004 Jun;45(6):1667-73 |
1 | J:333326 Suh J, Kim NK, Shim W, Lee SH, Kim HJ, Moon E, Sesaki H, Jang JH, Kim JE, Lee YS, Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab. 2023 Feb 7;35(2):345-360.e7 |
Opa3 optic atrophy 3 (Synonyms: D630048P19Rik, LOC243868, LOC384570) | |
Results | Reference |
1* | J:181412 Powell KA, Davies JR, Taylor E, Wride MA, Votruba M, Mitochondrial localization and ocular expression of mutant Opa3 in a mouse model of 3-methylglutaconicaciduria type III. Invest Ophthalmol Vis Sci. 2011 Jun;52(7):4369-80 |
Opcml opioid binding protein/cell adhesion molecule-like (Synonyms: 2900075O15Rik, B930023M13Rik, LOC235104, MGC:99974, Obcam) | |
Results | Reference |
1* | J:312430 Fearnley S, Raja R, Cloutier JF, Spatiotemporal expression of IgLON family members in the developing mouse nervous system. Sci Rep. 2021 Oct 1;11(1):19536 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Ophn1 oligophrenin 1 (Synonyms: C130037N19Rik, Wtgr) | |
Results | Reference |
3* | J:85384 Fauchereau F, Herbrand U, Chafey P, Eberth A, Koulakoff A, Vinet MC, Ahmadian MR, Chelly J, Billuart P, The RhoGAP activity of OPHN1, a new F-actin-binding protein, is negatively controlled by its amino-terminal domain. Mol Cell Neurosci. 2003 Aug;23(4):574-86 |
Opn1sw opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan) (Synonyms: Bcp, Blue Cone Opsin, Blue Opsin, Blue/UV Opsin, Short Wavelength Sensitive opsin, S Opsin, SWS opsin, UV cone pigment) | |
Results | Reference |
1* | J:225638 Yoshida S, Mears AJ, Friedman JS, Carter T, He S, Oh E, Jing Y, Farjo R, Fleury G, Barlow C, Hero AO, Swaroop A, Expression profiling of the developing and mature Nrl-/- mouse retina: identification of retinal disease candidates and transcriptional regulatory targets of Nrl. Hum Mol Genet. 2004 Jul 15;13(14):1487-503 |
Opn4 opsin 4 (melanopsin) (Synonyms: 1110007J02Rik) | |
Results | Reference |
1 | J:223559 Goetz JJ, Martin GM, Chowdhury R, Trimarchi JM, Onecut1 and Onecut2 play critical roles in the development of the mouse retina. PLoS One. 2014;9(10):e110194 |
1* | J:286801 Kiyama T, Mao CA, Ultrasensitive RNAscope In Situ Hybridization System on Embryonic and Adult Mouse Retinas. Methods Mol Biol. 2020;2092:147-158 |
Oprd1 opioid receptor, delta 1 (Synonyms: DOR, DOR-1, mDOR, Nbor) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1 | J:80266 Le Moine C, Fauchey V, Jaber M, Opioid receptor gene expression in dopamine transporter knock-out mice in adult and during development. Neuroscience. 2002;112(1):131-9 |
1 | J:231738 Reed-Geaghan EG, Wright MC, See LA, Adelman PC, Lee KH, Koerber HR, Maricich SM, Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. J Neurosci. 2016 Apr 13;36(15):4362-76 |
Oprk1 opioid receptor, kappa 1 (Synonyms: KOR-1, Oprk2, R21) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1 | J:80266 Le Moine C, Fauchey V, Jaber M, Opioid receptor gene expression in dopamine transporter knock-out mice in adult and during development. Neuroscience. 2002;112(1):131-9 |
Oprl1 opioid receptor-like 1 (Synonyms: LC132, morc, MOR-C, nociceptin/ orphaninFQ receptor, N/OFQ receptor, NOP, ORL1, XOR1) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Oprm1 opioid receptor, mu 1 (Synonyms: MOP-R, MOP receptor, mor, MOR-1, muOR, Oprm) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1 | J:80266 Le Moine C, Fauchey V, Jaber M, Opioid receptor gene expression in dopamine transporter knock-out mice in adult and during development. Neuroscience. 2002;112(1):131-9 |
Optc opticin | |
Results | Reference |
1 | J:141138 Zhang Y, Burgess D, Overbeek PA, Govindarajan V, Dominant inhibition of lens placode formation in mice. Dev Biol. 2008 Nov 1;323(1):53-63 |
Optn optineurin (Synonyms: 4930441O07Rik, TFIIIA-INTP) | |
Results | Reference |
1 | J:356661 Esteban-Martinez L, Sierra-Filardi E, McGreal RS, Salazar-Roa M, Marino G, Seco E, Durand S, Enot D, Grana O, Malumbres M, Cvekl A, Cuervo AM, Kroemer G, Boya P, Programmed mitophagy is essential for the glycolytic switch during cell differentiation. EMBO J. 2017 Jun 14;36(12):1688-1706 |
Or1x2 olfactory receptor family 1 subfamily X member 2 (Synonyms: F3, GA_x6K02T2QP88-4411197-4410256, MOR126-1, Olfr54) | |
Results | Reference |
2* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or2ag15 olfactory receptor family 2 subfamily AG member 15 (Synonyms: GA_x6K02T2PBJ9-9119301-9118348, MOR283-5, Olfr697) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or2c1 olfactory receptor family 2 subfamily C member 1 (Synonyms: GA_x54KRFPKG5P-348087-349025, MOR256-17, Olfr15, OR3) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
1 | J:315559 Login H, Haglin S, Berghard A, Bohm S, The Stimulus-Dependent Gradient of Cyp26B1+ Olfactory Sensory Neurons Is Necessary for the Functional Integrity of the Olfactory Sensory Map. J Neurosci. 2015 Oct 7;35(40):13807-18 |
Or5p55 olfactory receptor family 5 subfamily P member 55 (Synonyms: GA_x6K02T2PBJ9-10296787-10297719, MOR204-3, Olfr476) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or6a2 olfactory receptor family 6 subfamily A member 2 (Synonyms: GA_x6K02T2PBJ9-9381439-9380456, I54, I7, MOR103-15, Olfr2, Olfr41) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or6z1 olfactory receptor family 6 subfamily Z member 1 (Synonyms: GA_x6K02T2QGBW-3232059-3231121, MOR103-9, Olfr1348) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or7a35 olfactory receptor family 7 subfamily A member 35 (Synonyms: GA_x6K02T2QGN0-2794907-2793948, MOR139-4, Olfr1351) | |
Results | Reference |
2* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or8a1 olfactory receptor family 8 subfamily A member 1 (Synonyms: GA_x6K02T2PVTD-31408136-31407207, M71, MOR171-2, Olfr151) | |
Results | Reference |
1 | J:90847 Hirota J, Mombaerts P, The LIM-homeodomain protein Lhx2 is required for complete development of mouse olfactory sensory neurons. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8751-5 |
2* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or8a1b olfactory receptor family 8 subfamily A member 1B (Synonyms: GA_x6K02T2PVTD-31389446-31388517, M72, MOR171-3, MOR171-3, Olfr160) | |
Results | Reference |
1 | J:90847 Hirota J, Mombaerts P, The LIM-homeodomain protein Lhx2 is required for complete development of mouse olfactory sensory neurons. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8751-5 |
1 | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
1 | J:164033 Miller AM, Maurer LR, Zou DJ, Firestein S, Greer CA, Axon fasciculation in the developing olfactory nerve. Neural Dev. 2010;5(1):20 |
Or8u3 olfactory receptor family 8 subfamily U member 3 (Synonyms: GA_x6K02T2Q125-47591072-47592031, MOR185-3, Olfr1038-ps, Or8u3-ps) | |
Results | Reference |
2* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or10a4 olfactory receptor family 10 subfamily A member 4 (Synonyms: GA_x6K02T2PBJ9-9470146-9471093, MOR263-5, Olfr17, P2) | |
Results | Reference |
1 | J:90847 Hirota J, Mombaerts P, The LIM-homeodomain protein Lhx2 is required for complete development of mouse olfactory sensory neurons. Proc Natl Acad Sci U S A. 2004 Jun 8;101(23):8751-5 |
1 | J:164033 Miller AM, Maurer LR, Zou DJ, Firestein S, Greer CA, Axon fasciculation in the developing olfactory nerve. Neural Dev. 2010;5(1):20 |
Or10j5 olfactory receptor family 10 subfamily J member 5 (Synonyms: GA_x6K02T2R7CC-893157-892228, MOR23, MOR267-13, Olfr16) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
1* | J:195909 Lam RS, Mombaerts P, Odorant responsiveness of embryonic mouse olfactory sensory neurons expressing the odorant receptors S1 or MOR23. Eur J Neurosci. 2013 Jul;38(2):2210-7 |
Or11h4 olfactory receptor family 11 subfamily H member 4 (Synonyms: GA_x6K02T2PMLR-6484046-6483105, MOR106-1, Olfr749) | |
Results | Reference |
1* | J:195909 Lam RS, Mombaerts P, Odorant responsiveness of embryonic mouse olfactory sensory neurons expressing the odorant receptors S1 or MOR23. Eur J Neurosci. 2013 Jul;38(2):2210-7 |
Or51a39 olfactory receptor family 51 subfamily A member 39 (Synonyms: GA_x6K02T2PBJ9-5431102-5430146, MOR11-2, MTPCR33, Olfr33) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or51ai2 olfactory receptor family 51 subfamily AI member 2 (Synonyms: GA_x6K02T2PBJ9-6671256-6672209, MOR2-1, Olfr632) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or51b6 olfactory receptor family 51 subfamily B member 6 (Synonyms: 5'[b]3, GA_x6K02T2PBJ9-6634906-6633983, MOR1-2, Olfr65) | |
Results | Reference |
1 | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or51e2 olfactory receptor family 51 subfamily E member 2 (Synonyms: 4633402A21Rik, GA_x6K02T2PBJ9-5459657-5458695, MOL2.3, MOR18-2, Olfr78, PSGR, RA1c) | |
Results | Reference |
3* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or51f1d olfactory receptor family 51 subfamily F member 1D (Synonyms: GA_x6K02T2PBJ9-5762668-5763618, MOR14-6, Olfr583) | |
Results | Reference |
1 | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or51g1 olfactory receptor family 51 subfamily G member 1 (Synonyms: GA_x6K02T2PBJ9-5696486-5695545, MOR7-1, Olfr578) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or51l4 olfactory receptor family 51 subfamily L member 4 (Synonyms: GA_x6K02T2PBJ9-6483085-6482126, MOR17-1, Olfr630) | |
Results | Reference |
1 | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or51s1 olfactory receptor family 51 subfamily S member 1 (Synonyms: GA_x6K02T2PBJ9-5620890-5619922, MOR21-1, Olfr571) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or52a5b olfactory receptor family 52 subfamily A member 5B (Synonyms: 3'[b]3, GA_x6K02T2PBJ9-6494485-6493535, MOR22-2, Olfr69) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or52b1 olfactory receptor family 52 subfamily B member 1 (Synonyms: GA_x6K02T2PBJ9-7959171-7958224, MOR31-2, Olfr690) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or52b2 olfactory receptor family 52 subfamily B member 2 (Synonyms: GA_x6K02T2PBJ9-7966695-7965727, MOR31-6, Olfr691) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or52e15 olfactory receptor family 52 subfamily E member 15 (Synonyms: GA_x6K02T2PBJ9-7625746-7624808, MOR32-4, Olfr672) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or52e19b olfactory receptor family 52 subfamily E member 19B (Synonyms: GA_x6K02T2PBJ9-6092550-6092362, GA_x6K02T2PBJ9-6096387-6095449, MOR32-14_i, MOR32-2, Olfr603, Olfr604) | |
Results | Reference |
1* | J:226858 Baker NL, Miller KA, Newgreen DF, Farlie PG, Olfr603, an orphan olfactory receptor, is expressed in multiple specific embryonic tissues. Gene Expr Patterns. 2015 Sep-Nov;19(1-2):30-5 |
Or52h7 olfactory receptor family 52 subfamily H member 7 (Synonyms: GA_x6K02T2PBJ9-7191524-7192471, MOR31-8, Olfr652) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or52i2 olfactory receptor family 52 subfamily J member 2 (Synonyms: GA_x6K02T2PBJ9-5386601-5387575, MOR41-1, Olfr556) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or52k2 olfactory receptor family 52 subfamily K member 2 (Synonyms: GA_x6K02T2PBJ9-5323062-5324015, MOR28-1, Olfr552) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or52n3 olfactory receptor family 52 subfamily N member 3 (Synonyms: GA_x6K02T2PBJ9-7509539-7510489, MOR34-7, Olfr665) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or52x1 olfactory receptor family 52 subfamily X member 1 (Synonyms: GA_x6K02T2PBJ9-7832633-7831680, MOR35-1, Olfr686) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or55b10 olfactory receptor family 55 subfamily B member 10 (Synonyms: GA_x6K02T2PBJ9-5216160-5215210, MOR42-1, Olfr545, S50) | |
Results | Reference |
2* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Or56a5 olfactory receptor family 56 subfamily A member 5 (Synonyms: GA_x6K02T2PBJ9-7773007-7772066, MOR40-1, Olfr683) | |
Results | Reference |
1* | J:123232 Hirota J, Omura M, Mombaerts P, Differential impact of Lhx2 deficiency on expression of class I and class II odorant receptor genes in mouse. Mol Cell Neurosci. 2007 Apr;34(4):679-88 |
Osbpl1a oxysterol binding protein-like 1A (Synonyms: G430090F17Rik, LOC328902) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Osbpl8 oxysterol binding protein-like 8 (Synonyms: D330025H14Rik, ORP-8) | |
Results | Reference |
1 | J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005 |
Osm oncostatin M (Synonyms: OncoM) | |
Results | Reference |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
1 | J:314320 Wang H, Kane AW, Lee C, Ahn S, Gli3 repressor controls cell fates and cell adhesion for proper establishment of neurogenic niche. Cell Rep. 2014 Aug 21;8(4):1093-104 |
Osmr oncostatin M receptor (Synonyms: OSMRB) | |
Results | Reference |
1* | J:120667 Bouzin C, Clotman F, Renauld JC, Lemaigre FP, Rousseau GG, The onecut transcription factor hepatocyte nuclear factor-6 controls B lymphopoiesis in fetal liver. J Immunol. 2003 Aug 1;171(3):1297-303 |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
1 | J:314320 Wang H, Kane AW, Lee C, Ahn S, Gli3 repressor controls cell fates and cell adhesion for proper establishment of neurogenic niche. Cell Rep. 2014 Aug 21;8(4):1093-104 |
Osr1 odd-skipped related transcription factor 1 (Synonyms: Odd1) | |
Results | Reference |
1 | J:336858 Vallecillo-Garcia P, Orgeur M, Comai G, Poehle-Kronnawitter S, Fischer C, Gloger M, Dumas CE, Giesecke-Thiel C, Sauer S, Tajbakhsh S, Hopken UE, Stricker S, A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation. Immunity. 2023 Jun 13;56(6):1204-1219.e8 |
1 | J:208647 Xu J, Liu H, Park JS, Lan Y, Jiang R, Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesis. Development. 2014 Apr;141(7):1442-52 |
Osr2 odd-skipped related 2 (Synonyms: 5430409I15Rik, Osr2A, Osr2B) | |
Results | Reference |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
2 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Ostn osteocrin (Synonyms: musclin, Ostc) | |
Results | Reference |
1* | J:87170 Thomas G, Moffatt P, Salois P, Gaumond MH, Gingras R, Godin E, Miao D, Goltzman D, Lanctot C, Osteocrin, a novel bone-specific secreted protein that modulates the osteoblast phenotype. J Biol Chem. 2003 Dec 12;278(50):50563-71 |
Otoa otoancorin | |
Results | Reference |
1* | J:76334 Zwaenepoel I, Mustapha M, Leibovici M, Verpy E, Goodyear R, Liu XZ, Nouaille S, Nance WE, Kanaan M, Avraham KB, Tekaia F, Loiselet J, Lathrop M, Richardson G, Petit C, Otoancorin, an inner ear protein restricted to the interface between the apical surface of sensory epithelia and their overlying acellular gels, is defective in autosomal recessive deafness DFNB22. Proc Natl Acad Sci U S A. 2002 Apr 30;99(9):6240-5 |
Otog otogelin (Synonyms: Otgn) | |
Results | Reference |
2* | J:74163 El-Amraoui A, Cohen-Salmon M, Petit C, Simmler MC, Spatiotemporal expression of otogelin in the developing and adult mouse inner ear. Hear Res. 2001 Aug;158(1-2):151-9 |
1 | J:245765 Goodyear RJ, Lu X, Deans MR, Richardson GP, A tectorin-based matrix and planar cell polarity genes are required for normal collagen-fibril orientation in the developing tectorial membrane. Development. 2017 Nov 01;144(21):3978-3989 |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Otop1 otopetrin 1 (Synonyms: A530025J20Rik, tlt) | |
Results | Reference |
2* | J:82639 Hurle B, Ignatova E, Massironi SM, Mashimo T, Rios X, Thalmann I, Thalmann R, Ornitz DM, Non-syndromic vestibular disorder with otoconial agenesis in tilted/mergulhador mice caused by mutations in otopetrin 1. Hum Mol Genet. 2003 Apr 1;12(7):777-89 |
2* | J:171566 Kim E, Hyrc KL, Speck J, Lundberg YW, Salles FT, Kachar B, Goldberg MP, Warchol ME, Ornitz DM, Regulation of cellular calcium in vestibular supporting cells by otopetrin 1. J Neurophysiol. 2010 Dec;104(6):3439-50 |
Otp orthopedia homeobox | |
Results | Reference |
1* | J:87378 Cremona M, Colombo E, Andreazzoli M, Cossu G, Broccoli V, Bsx, an evolutionary conserved Brain Specific homeoboX gene expressed in the septum, epiphysis, mammillary bodies and arcuate nucleus. Gene Expr Patterns. 2004 Jan;4(1):47-51 |
1 | J:304355 Garcia-Calero E, Lopez-Gonzalez L, Martinez-de-la-Torre M, Fan CM, Puelles L, Sim1-expressing cells illuminate the origin and course of migration of the nucleus of the lateral olfactory tract in the mouse amygdala. Brain Struct Funct. 2021 Mar;226(2):519-562 |
1 | J:263715 Lee B, Kim J, An T, Kim S, Patel EM, Raber J, Lee SK, Lee S, Lee JW, Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons. Nat Commun. 2018 May 23;9(1):2026 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Otx1 orthodenticle homeobox 1 (Synonyms: A730044F23Rik, jv) | |
Results | Reference |
1 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1 | J:264980 Coffinier C, Jung HJ, Nobumori C, Chang S, Tu Y, Barnes RH 2nd, Yoshinaga Y, de Jong PJ, Vergnes L, Reue K, Fong LG, Young SG, Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell. 2011 Dec;22(23):4683-93 |
1 | J:176438 Esteve P, Sandonis A, Ibanez C, Shimono A, Guerrero I, Bovolenta P, Secreted frizzled-related proteins are required for Wnt/{beta}-catenin signalling activation in the vertebrate optic cup. Development. 2011 Oct;138(19):4179-84 |
1 | J:239666 Hagglund AC, Jones I, Carlsson L, A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development. Dis Model Mech. 2017 Mar 01;10(3):245-257 |
1 | J:183997 Langer L, Taranova O, Sulik K, Pevny L, SOX2 hypomorphism disrupts development of the prechordal floor and optic cup. Mech Dev. 2012 Mar;129(1-4):1-12 |
1* | J:221341 Lun MP, Johnson MB, Broadbelt KG, Watanabe M, Kang YJ, Chau KF, Springel MW, Malesz A, Sousa AM, Pletikos M, Adelita T, Calicchio ML, Zhang Y, Holtzman MJ, Lidov HG, Sestan N, Steen H, Monuki ES, Lehtinen MK, Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production. J Neurosci. 2015 Mar 25;35(12):4903-16 |
1 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
1 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1* | J:78146 Zhang Y, Miki T, Iwanaga T, Koseki Y, Okuno M, Sunaga Y, Ozaki N, Yano H, Koseki H, Seino S, Identification, tissue expression, and functional characterization of Otx3, a novel member of the Otx family. J Biol Chem. 2002 Aug 2;277(31):28065-9 |
Otx2 orthodenticle homeobox 2 (Synonyms: E130306E05Rik) | |
Results | Reference |
1 | J:185533 Achim K, Peltopuro P, Lahti L, Li J, Salminen M, Partanen J, Distinct developmental origins and regulatory mechanisms for GABAergic neurons associated with dopaminergic nuclei in the ventral mesodiencephalic region. Development. 2012 Jul;139(13):2360-70 |
1 | J:188155 Bharti K, Gasper M, Ou J, Brucato M, Clore-Gronenborn K, Pickel J, Arnheiter H, A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development. PLoS Genet. 2012 Jul;8(7):e1002757 |
1* | J:332642 Cohen-Gulkar M, David A, Messika-Gold N, Eshel M, Ovadia S, Zuk-Bar N, Idelson M, Cohen-Tayar Y, Reubinoff B, Ziv T, Shamay M, Elkon R, Ashery-Padan R, The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration. PLoS Biol. 2023 Jan;21(1):e3001924 |
1 | J:358820 Dudukcu O, Raj DDA, van de Haar LL, Grossouw LM, Linders LE, Garritsen O, Adolfs Y, van Kronenburg NCH, Broekhoven MH, Kapteijns THW, Meye FJ, Pasterkamp RJ, Molecular diversity and migration of GABAergic neurons in the developing ventral midbrain. iScience. 2024 Nov 15;27(11):111239 |
1 | J:172287 Esteve P, Sandonis A, Cardozo M, Malapeira J, Ibanez C, Crespo I, Marcos S, Gonzalez-Garcia S, Toribio ML, Arribas J, Shimono A, Guerrero I, Bovolenta P, SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis. Nat Neurosci. 2011 May;14(5):562-9 |
1 | J:176438 Esteve P, Sandonis A, Ibanez C, Shimono A, Guerrero I, Bovolenta P, Secreted frizzled-related proteins are required for Wnt/{beta}-catenin signalling activation in the vertebrate optic cup. Development. 2011 Oct;138(19):4179-84 |
1* | J:130649 Fossat N, Le Greneur C, Beby F, Vincent S, Godement P, Chatelain G, Lamonerie T, A new GFP-tagged line reveals unexpected Otx2 protein localization in retinal photoreceptors. BMC Dev Biol. 2007;7:122 |
1 | J:249145 Goetz JJ, Laboissonniere LA, Wester AK, Lynch MR, Trimarchi JM, Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression. PLoS One. 2016;11(3):e0150878 |
1 | J:223559 Goetz JJ, Martin GM, Chowdhury R, Trimarchi JM, Onecut1 and Onecut2 play critical roles in the development of the mouse retina. PLoS One. 2014;9(10):e110194 |
1 | J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6 |
1 | J:237402 Iwai-Takekoshi L, Ramos A, Schaler A, Weinreb S, Blazeski R, Mason C, Retinal pigment epithelial integrity is compromised in the developing albino mouse retina. J Comp Neurol. 2016 Dec 15;524(18):3696-3716 |
2 | J:194049 Johansson PA, Irmler M, Acampora D, Beckers J, Simeone A, Gotz M, The transcription factor Otx2 regulates choroid plexus development and function. Development. 2013 Mar;140(5):1055-66 |
1 | J:147995 Kawauchi S, Kim J, Santos R, Wu HH, Lander AD, Calof AL, Foxg1 promotes olfactory neurogenesis by antagonizing Gdf11. Development. 2009 May;136(9):1453-64 |
1* | J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347 |
1 | J:285747 Liu S, Liu X, Li S, Huang X, Qian H, Jin K, Xiang M, Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5016-5027 |
1* | J:346057 Lu D, Zhi Y, Su H, Lin X, Lin J, Shi Y, Yi W, Hong C, Zhang T, Fu Z, Chen LY, Zhao Z, Li R, Xu Z, Chen W, Wang N, Xu D, ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells. Cell Rep. 2024 Feb 24;43(3):113818 |
1* | J:35538 Mallamaci A, Di Blas E, Briata P, Boncinelli E, Corte G, OTX2 homeoprotein in the developing central nervous system and migratory cells of the olfactory area. Mech Dev. 1996 Aug;58(1-2):165-78 |
1 | J:219894 Mattar P, Ericson J, Blackshaw S, Cayouette M, A conserved regulatory logic controls temporal identity in mouse neural progenitors. Neuron. 2015 Feb 4;85(3):497-504 |
2* | J:175980 Mortensen AH, MacDonald JW, Ghosh D, Camper SA, Candidate genes for panhypopituitarism identified by gene expression profiling. Physiol Genomics. 2011 Oct 6;43(19):1105-16 |
1 | J:320719 Parichha A, Suresh V, Chatterjee M, Kshirsagar A, Ben-Reuven L, Olender T, Taketo MM, Radosevic V, Bobic-Rasonja M, Trnski S, Holtzman MJ, Jovanov-Milosevic N, Reiner O, Tole S, Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate. Nat Commun. 2022 Feb 2;13(1):633 |
1 | J:296045 Patmore DM, Jassim A, Nathan E, Gilbertson RJ, Tahan D, Hoffmann N, Tong Y, Smith KS, Kanneganti TD, Suzuki H, Taylor MD, Northcott P, Gilbertson RJ, DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma. Dev Cell. 2020 Aug 24;54(4):455-470.e5 |
1 | J:321252 Pereira Luppi M, Azcorra M, Caronia-Brown G, Poulin JF, Gaertner Z, Gatica S, Moreno-Ramos OA, Nouri N, Dubois M, Ma YC, Ramakrishnan C, Fenno L, Kim YS, Deisseroth K, Cicchetti F, Dombeck DA, Awatramani R, Sox6 expression distinguishes dorsally and ventrally biased dopamine neurons in the substantia nigra with distinctive properties and embryonic origins. Cell Rep. 2021 Nov 9;37(6):109975 |
1 | J:347618 Qin T, So KKH, Hui CC, Sham MH, Ptch1 is essential for cochlear marginal cell differentiation and stria vascularis formation. Cell Rep. 2024 Apr 23;43(4):114083 |
1 | J:77026 Rachel RA, Dolen G, Hayes NL, Lu A, Erskine L, Nowakowski RS, Mason CA, Spatiotemporal features of early neuronogenesis differ in wild-type and albino mouse retina. J Neurosci. 2002 Jun 1;22(11):4249-63 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:160518 Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, Jenkins RB, Tihan T, Vandenberg SR, James CD, Tanaka K, Taylor MD, Weiss WA, Chesler L, Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010 May 15;24(10):1059-72 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1* | J:336871 Toonen JA, Ronchetti A, Sidjanin DJ, A Disintegrin and Metalloproteinase10 (ADAM10) Regulates NOTCH Signaling during Early Retinal Development. PLoS One. 2016;11(5):e0156184 |
1* | J:78146 Zhang Y, Miki T, Iwanaga T, Koseki Y, Okuno M, Sunaga Y, Ozaki N, Yano H, Koseki H, Seino S, Identification, tissue expression, and functional characterization of Otx3, a novel member of the Otx family. J Biol Chem. 2002 Aug 2;277(31):28065-9 |
1 | J:217063 Zou M, Luo H, Xiang M, Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord. Dev Dyn. 2015 Jan;244(1):86-97 |
Ovol1 ovo like zinc finger 1 (Synonyms: movo1, Ovo1) | |
Results | Reference |
1 | J:355647 Bugacov H, Der B, Briantseva BM, Guo Q, Kim S, Lindstrom NO, McMahon AP, Dose-dependent responses to canonical Wnt transcriptional complexes in the regulation of mammalian nephron progenitors. Development. 2024 Sep 15;151(18) |
1 | J:50844 Dai X, Schonbaum C, Degenstein L, Bai W, Mahowald A, Fuchs E, The ovo gene required for cuticle formation and oogenesis in flies is involved in hair formation and spermatogenesis in mice. Genes Dev. 1998 Nov 1;12(21):3452-63 |
1 | J:101702 Li B, Nair M, Mackay DR, Bilanchone V, Hu M, Fallahi M, Song H, Dai Q, Cohen PE, Dai X, Ovol1 regulates meiotic pachytene progression during spermatogenesis by repressing Id2 expression. Development. 2005 Mar;132(6):1463-73 |
1* | J:121663 Nair M, Bilanchone V, Ortt K, Sinha S, Dai X, Ovol1 represses its own transcription by competing with transcription activator c-Myb and by recruiting histone deacetylase activity. Nucleic Acids Res. 2007;35(5):1687-97 |
Ovol2 ovo like zinc finger 2 (Synonyms: 1810007D21Rik, M-OVO, movo2, M-OVO-A, M-OVO-B, Ovol2, Zfp339) | |
Results | Reference |
1 | J:213415 Lee B, Villarreal-Ponce A, Fallahi M, Ovadia J, Sun P, Yu QC, Ito S, Sinha S, Nie Q, Dai X, Transcriptional mechanisms link epithelial plasticity to adhesion and differentiation of epidermal progenitor cells. Dev Cell. 2014 Apr 14;29(1):47-58 |
Oxt oxytocin (Synonyms: Oxy) | |
Results | Reference |
1* | J:49030 Jing X, Ratty AK, Murphy D, Ontogeny of the vasopressin and oxytocin RNAs in the mouse hypothalamus. Neurosci Res. 1998 Apr;30(4):343-9 |
2 | J:308477 Madrigal MP, Jurado S, Specification of oxytocinergic and vasopressinergic circuits in the developing mouse brain. Commun Biol. 2021 May 14;4(1):586 |
Oxtr oxytocin receptor (Synonyms: OTR) | |
Results | Reference |
1 | J:294332 Romanov RA, Tretiakov EO, Kastriti ME, Zupancic M, Haring M, Korchynska S, Popadin K, Benevento M, Rebernik P, Lallemend F, Nishimori K, Clotman F, Andrews WD, Parnavelas JG, Farlik M, Bock C, Adameyko I, Hokfelt T, Keimpema E, Harkany T, Molecular design of hypothalamus development. Nature. 2020 Jun;582(7811):246-252 |
P2rx3 purinergic receptor P2X, ligand-gated ion channel, 3 (Synonyms: 4930513E20Rik, MGC:28163, P2X3) | |
Results | Reference |
1 | J:209845 Fei D, Krimm RF, Taste neurons consist of both a large TrkB-receptor-dependent and a small TrkB-receptor-independent subpopulation. PLoS One. 2013;8(12):e83460 |
1* | J:217303 Koudelka J, Horn JM, Vatanashevanopakorn C, Minichiello L, Genetic dissection of TrkB activated signalling pathways required for specific aspects of the taste system. Neural Dev. 2014;9:21 |
1 | J:108169 Ruan HZ, Moules E, Burnstock G, Changes in P2X3 purinoceptors in sensory ganglia of the mouse during embryonic and postnatal development. Histochem Cell Biol. 2004 Dec;122(6):539-51 |
1 | J:302429 Wang Z, Jung JS, Inbar TC, Rangoussis KM, Faaborg-Andersen C, Coate TM, The Purinergic Receptor P2rx3 is Required for Spiral Ganglion Neuron Branch Refinement during Development. eNeuro. 2020 Jul/Aug;7(4):ENEURO.0179-20.2020 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
P2ry12 purinergic receptor P2Y, G-protein coupled 12 (Synonyms: 2900079B22Rik, 4921504D23Rik, P2Y12) | |
Results | Reference |
1* | J:333946 Hattori Y, Kato D, Murayama F, Koike S, Asai H, Yamasaki A, Naito Y, Kawaguchi A, Konishi H, Prinz M, Masuda T, Wake H, Miyata T, CD206(+) macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia. Cell Rep. 2023 Feb 7;42(2):112092 |
1 | J:326459 Scott EP, Breyak E, Nishinakamura R, Nakagawa Y, The zinc finger transcription factor Sall1 is required for the early developmental transition of microglia in mouse embryos. Glia. 2022 Sep;70(9):1720-1733 |
P3h3 prolyl 3-hydroxylase 3 (Synonyms: Grcb, Leprel2) | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
P3h4 prolyl 3-hydroxylase family member 4 (non-enzymatic) (Synonyms: 1110036O03Rik, Leprel4) | |
Results | Reference |
1* | J:241120 Gruenwald K, Castagnola P, Besio R, Dimori M, Chen Y, Akel NS, Swain FL, Skinner RA, Eyre DR, Gaddy D, Suva LJ, Morello R, Sc65 is a novel endoplasmic reticulum protein that regulates bone mass homeostasis. J Bone Miner Res. 2014 Mar;29(3):666-75 |
P4ha1 procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide (Synonyms: P4ha) | |
Results | Reference |
1 | J:251718 Pietila I, Prunskaite-Hyyrylainen R, Kaisto S, Tika E, van Eerde AM, Salo AM, Garma L, Miinalainen I, Feitz WF, Bongers EM, Juffer A, Knoers NV, Renkema KY, Myllyharju J, Vainio SJ, Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning. PLoS One. 2016;11(1):e0147171 |
Pa2g4 proliferation-associated 2G4 (Synonyms: Ebp1, Plfap) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Padi6 peptidyl arginine deiminase, type VI (Synonyms: ePAD, Pad6, Padi5) | |
Results | Reference |
1* | J:163620 Choi M, Lee OH, Jeon S, Park M, Lee DR, Ko JJ, Yoon TK, Rajkovic A, Choi Y, The oocyte-specific transcription factor, Nobox, regulates the expression of Pad6, a peptidylarginine deiminase in the oocyte. FEBS Lett. 2010 Aug 20;584(16):3629-34 |
Pafah1b1 platelet-activating factor acetylhydrolase, isoform 1b, subunit 1 (Synonyms: Lis1, LIS-1, lissencephaly-1 protein, Mdsh, PAF-AH 45, Pafaha) | |
Results | Reference |
1 | J:37333 Albrecht U, Abu-Issa R, Ratz B, Hattori M, Aoki J, Arai H, Inoue K, Eichele G, Platelet-activating factor acetylhydrolase expression and activity suggest a link between neuronal migration and platelet-activating factor. Dev Biol. 1996 Dec 15;180(2):579-93 |
1 | J:77999 Sugitani Y, Nakai S, Minowa O, Nishi M, Jishage K, Kawano H, Mori K, Ogawa M, Noda T, Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. Genes Dev. 2002 Jul 15;16(14):1760-5 |
2 | J:171513 Tian Y, Zhang Y, Hurd L, Hannenhalli S, Liu F, Lu MM, Morrisey EE, Regulation of lung endoderm progenitor cell behavior by miR302/367. Development. 2011 Apr;138(7):1235-45 |
1* | J:84075 Toyo-oka K, Shionoya A, Gambello MJ, Cardoso C, Leventer R, Ward HL, Ayala R, Tsai LH, Dobyns W, Ledbetter D, Hirotsune S, Wynshaw-Boris A, 14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nat Genet. 2003 Jul;34(3):274-85 |
Pafah1b2 platelet-activating factor acetylhydrolase, isoform 1b, subunit 2 (Synonyms: mus[b], PAF-AH 30, PAF-AH alpha2, Pafahb) | |
Results | Reference |
1 | J:37333 Albrecht U, Abu-Issa R, Ratz B, Hattori M, Aoki J, Arai H, Inoue K, Eichele G, Platelet-activating factor acetylhydrolase expression and activity suggest a link between neuronal migration and platelet-activating factor. Dev Biol. 1996 Dec 15;180(2):579-93 |
Pafah1b3 platelet-activating factor acetylhydrolase, isoform 1b, subunit 3 (Synonyms: mus[g], PAF-AH alpha1, Pafahg) | |
Results | Reference |
1 | J:37333 Albrecht U, Abu-Issa R, Ratz B, Hattori M, Aoki J, Arai H, Inoue K, Eichele G, Platelet-activating factor acetylhydrolase expression and activity suggest a link between neuronal migration and platelet-activating factor. Dev Biol. 1996 Dec 15;180(2):579-93 |
Paics phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase (Synonyms: 2610511I09Rik, ADE2H1, AIRC, PAIS) | |
Results | Reference |
1 | J:341495 Mizukoshi T, Yamada S, Sakakibara SI, Spatiotemporal Regulation of De Novo and Salvage Purine Synthesis during Brain Development. eNeuro. 2023 Oct;10(10):ENEURO.0159-23.2023 |
Pak1 p21 (RAC1) activated kinase 1 (Synonyms: PAK-1, Paka) | |
Results | Reference |
1 | J:157099 Grimsley-Myers CM, Sipe CW, Geleoc GS, Lu X, The small GTPase Rac1 regulates auditory hair cell morphogenesis. J Neurosci. 2009 Dec 16;29(50):15859-69 |
1 | J:79013 Hayashi K, Ohshima T, Mikoshiba K, Pak1 is involved in dendrite initiation as a downstream effector of rac1 in cortical neurons. Mol Cell Neurosci. 2002 Aug;20(4):579 |
Pak2 p21 (RAC1) activated kinase 2 (Synonyms: 5330420P17Rik, A130002K10Rik, D16Ertd269e, PAK-2) | |
Results | Reference |
1 | J:157099 Grimsley-Myers CM, Sipe CW, Geleoc GS, Lu X, The small GTPase Rac1 regulates auditory hair cell morphogenesis. J Neurosci. 2009 Dec 16;29(50):15859-69 |
1 | J:79013 Hayashi K, Ohshima T, Mikoshiba K, Pak1 is involved in dendrite initiation as a downstream effector of rac1 in cortical neurons. Mol Cell Neurosci. 2002 Aug;20(4):579 |
Pak3 p21 (RAC1) activated kinase 3 (Synonyms: PAK-3) | |
Results | Reference |
1 | J:126582 Cobos I, Borello U, Rubenstein JL, Dlx transcription factors promote migration through repression of axon and dendrite growth. Neuron. 2007 Jun 21;54(6):873-88 |
1 | J:157099 Grimsley-Myers CM, Sipe CW, Geleoc GS, Lu X, The small GTPase Rac1 regulates auditory hair cell morphogenesis. J Neurosci. 2009 Dec 16;29(50):15859-69 |
1 | J:79013 Hayashi K, Ohshima T, Mikoshiba K, Pak1 is involved in dendrite initiation as a downstream effector of rac1 in cortical neurons. Mol Cell Neurosci. 2002 Aug;20(4):579 |
1* | J:359452 Pang Y, Ruan X, Liu W, Hou L, Yin B, Shu P, Peng X, MicroRNA-495 Modulates Neuronal Layer Fate Determination by Targeting Tcf4. Int J Biol Sci. 2024;20(15):6207-6221 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Palld palladin, cytoskeletal associated protein (Synonyms: 2410003B16Rik) | |
Results | Reference |
1* | J:140659 Wang HV, Moser M, Comparative expression analysis of the murine palladin isoforms. Dev Dyn. 2008 Nov;237(11):3342-51 |
Palm paralemmin (Synonyms: mKIAA0270) | |
Results | Reference |
1* | J:102999 Castellini M, Wolf LV, Chauhan BK, Galileo DS, Kilimann MW, Cvekl A, Duncan MK, Palm is expressed in both developing and adult mouse lens and retina. BMC Ophthalmol. 2005 Jun 21;5:14 |
Pals1 protein associated with LIN7 1, MAGUK family member (Synonyms: 3830420B02Rik, Mpp5, Pals1) | |
Results | Reference |
1 | J:184469 Cho SH, Kim JY, Simons DL, Song JY, Le JH, Swindell EC, Jamrich M, Wu SM, Kim S, Genetic ablation of Pals1 in retinal progenitor cells models the retinal pathology of Leber congenital amaurosis. Hum Mol Genet. 2012 Jun 15;21(12):2663-76 |
1 | J:306225 Ezan J, Moreau MM, Mamo TM, Shimbo M, Decroo M, Richter M, Peyroutou R, Rachel R, Tissir F, de Anda FC, Sans N, Montcouquiol M, Early loss of Scribble affects cortical development, interhemispheric connectivity and psychomotor activity. Sci Rep. 2021 Apr 27;11(1):9106 |
1* | J:283394 Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S, Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162 |
1* | J:220858 Kim JY, Song JY, Karnam S, Park JY, Lee JJ, Kim S, Cho SH, Common and distinctive localization patterns of Crumbs polarity complex proteins in the mammalian eye. Gene Expr Patterns. 2015 Jan;17(1):31-7 |
Panx1 pannexin 1 | |
Results | Reference |
2* | J:139703 Tang W, Ahmad S, Shestopalov VI, Lin X, Pannexins are new molecular candidates for assembling gap junctions in the cochlea. Neuroreport. 2008 Aug 27;19(13):1253-7 |
Panx2 pannexin 2 | |
Results | Reference |
1* | J:139703 Tang W, Ahmad S, Shestopalov VI, Lin X, Pannexins are new molecular candidates for assembling gap junctions in the cochlea. Neuroreport. 2008 Aug 27;19(13):1253-7 |
Panx3 pannexin 3 (Synonyms: 4833413G11Rik) | |
Results | Reference |
1 | J:316655 Oh SK, Shin JO, Baek JI, Lee J, Bae JW, Ankamerddy H, Kim MJ, Huh TL, Ryoo ZY, Kim UK, Bok J, Lee KY, Pannexin 3 is required for normal progression of skeletal development in vertebrates. FASEB J. 2015 Nov;29(11):4473-84 |
Papln papilin, proteoglycan-like sulfated glycoprotein (Synonyms: E030033C16Rik) | |
Results | Reference |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Pappa2 pappalysin 2 (Synonyms: PAPP-A2, Pappe, PLAC3, placenta-specific 3, pregnancy-associated plasma preproprotein-A2, pregnancy-associated plasma protein-E) | |
Results | Reference |
1* | J:327983 Wang J, Noguchi S, Takizawa T, Negishi Y, Morita R, Luo SS, Takizawa T, Placenta-specific lncRNA 1600012P17Rik is expressed in spongiotrophoblast and glycogen trophoblast cells of mouse placenta. Histochem Cell Biol. 2022 Jul;158(1):65-78 |
Papss2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 (Synonyms: 1810018P12Rik, Atpsk2, Sk2) | |
Results | Reference |
2 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:309384 Neirijnck Y, Reginensi A, Renkema KY, Massa F, Kozlov VM, Dhib H, Bongers EMHF, Feitz WF, van Eerde AM, Lefebvre V, Knoers NVAM, Tabatabaei M, Schulz H, McNeill H, Schaefer F, Wegner M, Sock E, Schedl A, Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT). Kidney Int. 2018 May;93(5):1142-1153 |
1* | J:121115 Stelzer C, Brimmer A, Hermanns P, Zabel B, Dietz UH, Expression profile of Papss2 (3'-phosphoadenosine 5'-phosphosulfate synthase 2) during cartilage formation and skeletal development in the mouse embryo. Dev Dyn. 2007 May;236(5):1313-8 |
1 | J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10) |
Paqr9 progestin and adipoQ receptor family member IX (Synonyms: 1700020G04Rik, C730029A08Rik) | |
Results | Reference |
1* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
Pard3 par-3 family cell polarity regulator (Synonyms: ASIP, D8Ertd580e, Par3, PAR-3, Pard3a) | |
Results | Reference |
1 | J:130194 Costa MR, Wen G, Lepier A, Schroeder T, Gotz M, Par-complex proteins promote proliferative progenitor divisions in the developing mouse cerebral cortex. Development. 2008 Jan;135(1):11-22 |
1 | J:198427 Dudok JJ, Sanz AS, Lundvig DM, Wijnholds J, MPP3 is required for maintenance of the apical junctional complex, neuronal migration, and stratification in the developing cortex. J Neurosci. 2013 May 8;33(19):8518-27 |
2 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
1 | J:334107 Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J, Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice. Hum Mol Genet. 2022 Oct 10;31(20):3504-3520 |
1 | J:306060 Kindt KS, Akturk A, Jarysta A, Day M, Beirl A, Flonard M, Tarchini B, EMX2-GPR156-Galphai reverses hair cell orientation in mechanosensory epithelia. Nat Commun. 2021 May 17;12(1):2861 |
3 | J:273200 Landin Malt A, Dailey Z, Holbrook-Rasmussen J, Zheng Y, Hogan A, Du Q, Lu X, Par3 is essential for the establishment of planar cell polarity of inner ear hair cells. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4999-5008 |
1 | J:292113 Lin YN, Lee YS, Li SK, Tang TK, Loss of CPAP in developing mouse brain and its functional implication for human primary microcephaly. J Cell Sci. 2020 Jun 24;133(12):jcs243592 |
1 | J:294113 Lough KJ, Byrd KM, Descovich CP, Spitzer DC, Bergman AJ, Beaudoin GM 3rd, Reichardt LF, Williams SE, Telophase correction refines division orientation in stratified epithelia. Elife. 2019 Dec 13;8:e49249 |
1* | J:78857 Manabe N, Hirai S, Imai F, Nakanishi H, Takai Y, Ohno S, Association of ASIP/mPAR-3 with adherens junctions of mouse neuroepithelial cells. Dev Dyn. 2002 Sep;225(1):61-9 |
1 | J:191793 Schnatwinkel C, Niswander L, Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice. PLoS One. 2012;7(9):e44871 |
1* | J:253585 Siletti K, Tarchini B, Hudspeth AJ, Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles. Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):E11170-E11179 |
1 | J:206876 Song JY, Park R, Kim JY, Hughes L, Lu L, Kim S, Johnson RL, Cho SH, Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev Biol. 2014 Feb 15;386(2):281-90 |
1 | J:154910 Sugiyama Y, Akimoto K, Robinson ML, Ohno S, Quinlan RA, A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol. 2009 Dec 15;336(2):246-56 |
1 | J:302296 Vong KI, Ma TC, Li B, Leung TCN, Nong W, Ngai SM, Hui JHL, Jiang L, Kwan KM, SOX9-COL9A3-dependent regulation of choroid plexus epithelial polarity governs blood-cerebrospinal fluid barrier integrity. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2009568118 |
Pard6a par-6 family cell polarity regulator alpha (Synonyms: 0710008C04Rik, 2610010A15Rik, PAR6alpha, Par6c, TAX40, Tip-40) | |
Results | Reference |
1 | J:306543 Yu Z, Zeng J, Wang J, Cui Y, Song X, Zhang Y, Cheng X, Hou N, Teng Y, Lan Y, Chen Y, Yang X, Hepatocyte growth factor-regulated tyrosine kinase substrate is essential for endothelial cell polarity and cerebrovascular stability. Cardiovasc Res. 2021 Jan 21;117(2):533-546 |
Pard6b par-6 family cell polarity regulator beta | |
Results | Reference |
1 | J:140256 Hartleben B, Schweizer H, Lubben P, Bartram MP, Moller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB, Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. J Biol Chem. 2008 Aug 22;283(34):23033-8 |
1 | J:273200 Landin Malt A, Dailey Z, Holbrook-Rasmussen J, Zheng Y, Hogan A, Du Q, Lu X, Par3 is essential for the establishment of planar cell polarity of inner ear hair cells. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4999-5008 |
1 | J:306543 Yu Z, Zeng J, Wang J, Cui Y, Song X, Zhang Y, Cheng X, Hou N, Teng Y, Lan Y, Chen Y, Yang X, Hepatocyte growth factor-regulated tyrosine kinase substrate is essential for endothelial cell polarity and cerebrovascular stability. Cardiovasc Res. 2021 Jan 21;117(2):533-546 |
Parm1 prostate androgen-regulated mucin-like protein 1 (Synonyms: 2210012L08Rik, 9130213B05Rik) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Parp1 poly (ADP-ribose) polymerase family, member 1 (Synonyms: 5830444G22Rik, Adprp, Adprt1, PARP, parp-1, sPARP-1) | |
Results | Reference |
1 | J:287985 Bosze B, Moon MS, Kageyama R, Brown NL, Simultaneous Requirements for Hes1 in Retinal Neurogenesis and Optic Cup-Stalk Boundary Maintenance. J Neurosci. 2020 Feb 12;40(7):1501-1513 |
1 | J:303632 Bosze B, Suarez-Navarro J, Soofi A, Lauderdale JD, Dressler GR, Brown NL, Multiple roles for Pax2 in the embryonic mouse eye. Dev Biol. 2021 Apr;472:18-29 |
1* | J:265712 Dziedzic SA, Su Z, Jean Barrett V, Najafov A, Mookhtiar AK, Amin P, Pan H, Sun L, Zhu H, Ma A, Abbott DW, Yuan J, ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC. Nat Cell Biol. 2018 Jan;20(1):58-68 |
1 | J:196310 Ene AC, Park S, Edelmann W, Taketo T, Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression. Dev Biol. 2013 May 1;377(1):213-23 |
1 | J:326085 Huang TC, Wang YF, Vazquez-Ferrer E, Theofel I, Requena CE, Hanna CW, Kelsey G, Hajkova P, Sex-specific chromatin remodelling safeguards transcription in germ cells. Nature. 2021 Dec;600(7890):737-742 |
1 | J:335423 Jia S, Wilbourne J, Crossen MJ, Zhao F, Morphogenesis of the female reproductive tract along antero-posterior and dorso-ventral axes is dependent on Amhr2+ mesenchyme in mice. Biol Reprod. 2022 Dec 10;107(6):1477-1489 |
1 | J:294981 Liu X, Castle V, Taketo T, Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development. Cell Death Dis. 2019 Oct 17;10(11):790 |
1 | J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77 |
Parp6 poly (ADP-ribose) polymerase family, member 6 (Synonyms: 1700119G14Rik, 2310028P13Rik, 3110038K10Rik, C030013N01Rik) | |
Results | Reference |
2 | J:301690 Huang JY, Wang K, Vermehren-Schmaedick A, Adelman JP, Cohen MS, PARP6 is a Regulator of Hippocampal Dendritic Morphogenesis. Sci Rep. 2016 Jan 4;6:18512 |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1* | J:281311 Nakano Y, Wiechert S, Banfi B, Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8 |
1 | J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12) |
Patj PATJ, crumbs cell polarity complex component (Synonyms: Cipp, Inadl) | |
Results | Reference |
1* | J:220858 Kim JY, Song JY, Karnam S, Park JY, Lee JJ, Kim S, Cho SH, Common and distinctive localization patterns of Crumbs polarity complex proteins in the mammalian eye. Gene Expr Patterns. 2015 Jan;17(1):31-7 |
Pax1 paired box 1 (Synonyms: hbs, hunchback, Pax-1, wavy tail, wt) | |
Results | Reference |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1* | J:9186 Deutsch U, Dressler GR, Gruss P, Pax 1, a member of a paired box homologous murine gene family, is expressed in segmented structures during development. Cell. 1988 May 20;53(4):617-25 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1* | J:28311 Neubuser A, Koseki H, Balling R, Characterization and developmental expression of Pax9, a paired-box-containing gene related to Pax1. Dev Biol. 1995 Aug;170(2):701-16 |
Pax2 paired box 2 (Synonyms: Opdc, Pax-2) | |
Results | Reference |
1 | J:127387 Armentano M, Chou SJ, Tomassy GS, Leingartner A, O'Leary DD, Studer M, COUP-TFI regulates the balance of cortical patterning between frontal/motor and sensory areas. Nat Neurosci. 2007 Oct;10(10):1277-86 |
1 | J:226938 Bagherie-Lachidan M, Reginensi A, Pan Q, Zaveri HP, Scott DA, Blencowe BJ, Helmbacher F, McNeill H, Stromal Fat4 acts non-autonomously with Dchs1/2 to restrict the nephron progenitor pool. Development. 2015 Aug 1;142(15):2564-73 |
1* | J:352627 Baltar J, Miranda RM, Cabral M, Rebelo S, Grahammer F, Huber TB, Reguenga C, Monteiro FA, Neph1 is required for neurite branching and is negatively regulated by the PRRXL1 homeodomain factor in the developing spinal cord dorsal horn. Neural Dev. 2024 Jul 24;19(1):13 |
1* | J:74241 Barbieri AM, Broccoli V, Bovolenta P, Alfano G, Marchitiello A, Mocchetti C, Crippa L, Bulfone A, Marigo V, Ballabio A, Banfi S, Vax2 inactivation in mouse determines alteration of the eye dorsal-ventral axis, misrouting of the optic fibres and eye coloboma. Development. 2002 Feb;129(3):805-13 |
2 | J:184000 Baubet V, Xiang C, Molczan A, Roccograndi L, Melamed S, Dahmane N, Rp58 is essential for the growth and patterning of the cerebellum and for glutamatergic and GABAergic neuron development. Development. 2012 Jun;139(11):1903-9 |
1 | J:176604 Bell SM, Zhang L, Mendell A, Xu Y, Haitchi HM, Lessard JL, Whitsett JA, Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. Dev Biol. 2011 Oct 1;358(1):79-90 |
1 | J:262819 Bohnenpoll T, Feraric S, Nattkemper M, Weiss AC, Rudat C, Meuser M, Trowe MO, Kispert A, Diversification of Cell Lineages in Ureter Development. J Am Soc Nephrol. 2017 Jun;28(6):1792-1801 |
1 | J:303632 Bosze B, Suarez-Navarro J, Soofi A, Lauderdale JD, Dressler GR, Brown NL, Multiple roles for Pax2 in the embryonic mouse eye. Dev Biol. 2021 Apr;472:18-29 |
1 | J:90585 Cheng L, Arata A, Mizuguchi R, Qian Y, Karunaratne A, Gray PA, Arata S, Shirasawa S, Bouchard M, Luo P, Chen CL, Busslinger M, Goulding M, Onimaru H, Ma Q, Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates. Nat Neurosci. 2004 May;7(5):510-7 |
1 | J:352476 Cunanan J, Rajyam SS, Sharif B, Udwan K, Rana A, De Gregorio V, Ricardo S, Elia A, Brooks B, Weins A, Pollak M, John R, Barua M, Mice with a Pax2 missense variant display impaired glomerular repair. Am J Physiol Renal Physiol. 2024 May 1;326(5):F704-F726 |
1 | J:83530 Dakubo GD, Wang YP, Mazerolle C, Campsall K, McMahon AP, Wallace VA, Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development. Development. 2003 Jul;130(13):2967-80 |
1 | J:119857 Desmots F, Russell HR, Lee Y, Boyd K, McKinnon PJ, The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development. Mol Cell Biol. 2005 Dec;25(23):10329-37 |
1* | J:10797 Dressler GR, Deutsch U, Chowdhury K, Nornes HO, Gruss P, Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system. Development. 1990 Aug;109(4):787-95 |
1 | J:30057 Dudley AT, Lyons KM, Robertson EJ, A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev. 1995 NOV 15;9(22):2795-2807 |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
1 | J:112207 Englund C, Kowalczyk T, Daza RA, Dagan A, Lau C, Rose MF, Hevner RF, Unipolar brush cells of the cerebellum are produced in the rhombic lip and migrate through developing white matter. J Neurosci. 2006 Sep 6;26(36):9184-95 |
1 | J:104125 Evans AL, Gage PJ, Expression of the homeobox gene Pitx2 in neural crest is required for optic stalk and ocular anterior segment development. Hum Mol Genet. 2005 Nov 15;14(22):3347-59 |
1* | J:139696 Fotaki V, Price DJ, Mason JO, Newly identified patterns of Pax2 expression in the developing mouse forebrain. BMC Dev Biol. 2008;8:79 |
1 | J:101176 Grieshammer U, Cebrian C, Ilagan R, Meyers E, Herzlinger D, Martin GR, FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons. Development. 2005 Sep;132(17):3847-57 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
2 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:130251 Hori K, Cholewa-Waclaw J, Nakada Y, Glasgow SM, Masui T, Henke RM, Wildner H, Martarelli B, Beres TM, Epstein JA, Magnuson MA, Macdonald RJ, Birchmeier C, Johnson JE, A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes Dev. 2008 Jan 15;22(2):166-78 |
1 | J:160335 Huang X, Liu J, Ketova T, Fleming JT, Grover VK, Cooper MK, Litingtung Y, Chiang C, Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8422-7 |
1 | J:239651 Hurtado R, Zewdu R, Mtui J, Liang C, Aho R, Kurylo C, Selleri L, Herzlinger D, Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning. Development. 2015 Aug 01;142(15):2653-64 |
1* | J:121262 Iizuka-Kogo A, Ishidao T, Akiyama T, Senda T, Abnormal development of urogenital organs in Dlgh1-deficient mice. Development. 2007 May;134(9):1799-807 |
1 | J:51285 Kalatzis V, Sahly I, El-Amraoui A, Petit C, Eya1 expression in the developing ear and kidney: towards the understanding of the pathogenesis of Branchio-Oto-Renal (BOR) syndrome. Dev Dyn. 1998 Dec;213(4):486-99 |
1 | J:168981 Kim JJ, Gill PS, Rotin L, van Eede M, Henkelman RM, Hui CC, Rosenblum ND, Suppressor of Fused Controls Mid-Hindbrain Patterning and Cerebellar Morphogenesis via GLI3 Repressor. J Neurosci. 2011 Feb 2;31(5):1825-36 |
1* | J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347 |
1 | J:152264 Koo SK, Hill JK, Hwang CH, Lin ZS, Millen KJ, Wu DK, Lmx1a maintains proper neurogenic, sensory, and non-sensory domains in the mammalian inner ear. Dev Biol. 2009 Sep 1;333(1):14-25 |
1 | J:228865 Law C, Schaan Profes M, Levesque M, Kaltschmidt JA, Verhage M, Kania A, Normal Molecular Specification and Neurodegenerative Disease-Like Death of Spinal Neurons Lacking the SNARE-Associated Synaptic Protein Munc18-1. J Neurosci. 2016 Jan 13;36(2):561-76 |
1* | J:73497 Lawoko-Kerali G, Rivolta MN, Holley M, Expression of the transcription factors GATA3 and Pax2 during development of the mammalian inner ear. J Comp Neurol. 2002 Jan 21;442(4):378-91 |
2 | J:143446 Liu C, Nathans J, An essential role for frizzled 5 in mammalian ocular development. Development. 2008 Nov;135(21):3567-76 |
1* | J:310860 Liu S, Wang Y, Lu Y, Li W, Liu W, Ma J, Sun F, Li M, Chen ZY, Su K, Li W, The Key Transcription Factor Expression in the Developing Vestibular and Auditory Sensory Organs: A Comprehensive Comparison of Spatial and Temporal Patterns. Neural Plast. 2018;2018:7513258 |
1 | J:178174 Matsumoto A, Susaki E, Onoyama I, Nakayama K, Hoshino M, Nakayama KI, Deregulation of the p57-E2F1-p53 axis results in nonobstructive hydrocephalus and cerebellar malformation in mice. Mol Cell Biol. 2011 Oct;31(20):4176-92 |
1* | J:67157 McCright B, Gao X, Shen L, Lozier J, Lan Y, Maguire M, Herzlinger D, Weinmaster G, Jiang R, Gridley T, Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development. 2001 Feb;128(4):491-502 |
1 | J:186318 Mohri Y, Oyama K, Sone M, Akamatsu A, Nishimori K, LGR4 Is Required for the Cell Survival of the Peripheral Mesenchyme at the Embryonic Stages of Nephrogenesis. Biosci Biotechnol Biochem. 2012 May 23;76(5):888-91 |
1 | J:258875 Mona B, Uruena A, Kollipara RK, Ma Z, Borromeo MD, Chang JC, Johnson JE, Repression by PRDM13 is critical for generating precision in neuronal identity. Elife. 2017 Aug 29;6:e25787 |
1 | J:327110 Mullen RD, Bellessort B, Levi G, Behringer RR, Distal-less homeobox genes Dlx5/6 regulate Mullerian duct regression. Front Endocrinol (Lausanne). 2022;13:916173 |
1 | J:120229 Narlis M, Grote D, Gaitan Y, Boualia SK, Bouchard M, Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney. J Am Soc Nephrol. 2007 Apr;18(4):1121-9 |
1 | J:309384 Neirijnck Y, Reginensi A, Renkema KY, Massa F, Kozlov VM, Dhib H, Bongers EMHF, Feitz WF, van Eerde AM, Lefebvre V, Knoers NVAM, Tabatabaei M, Schulz H, McNeill H, Schaefer F, Wegner M, Sock E, Schedl A, Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT). Kidney Int. 2018 May;93(5):1142-1153 |
1 | J:306107 Niborski LL, Paces-Fessy M, Ricci P, Bourgeois A, Magalhaes P, Kuzma-Kuzniarska M, Lesaulnier C, Reczko M, Declercq E, Zurbig P, Doucet A, Umbhauer M, Cereghini S, Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model. Dis Model Mech. 2021 May 1;14(5):dmm047498 |
1 | J:264647 O'Brien LL, Guo Q, Bahrami-Samani E, Park JS, Hasso SM, Lee YJ, Fang A, Kim AD, Guo J, Hong TM, Peterson KA, Lozanoff S, Raviram R, Ren B, Fogelgren B, Smith AD, Valouev A, McMahon AP, Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies. PLoS Genet. 2018 Jan;14(1):e1007181 |
1 | J:183783 Ortega MC, Cases O, Merchan P, Kozyraki R, Clemente D, de Castro F, Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development. Glia. 2012 May;60(6):851-66 |
1 | J:45929 Otteson DC, Shelden E, Jones JM, Kameoka J, Hitchcock PF, Pax2 expression and retinal morphogenesis in the normal and Krd mouse. Dev Biol. 1998 Jan 15;193(2):209-24 |
1* | J:72 Plachov D, Chowdhury K, Walther C, Simon D, Guenet JL, Gruss P, Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland. Development. 1990 Oct;110(2):643-51 |
1 | J:270726 Shimada IS, Hwang SH, Somatilaka BN, Wang X, Skowron P, Kim J, Kim M, Shelton JM, Rajaram V, Xuan Z, Taylor MD, Mukhopadhyay S, Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis. Cell Rep. 2018 Jan 30;22(5):1169-1184 |
1 | J:116148 Stolt CC, Schlierf A, Lommes P, Hillgartner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M, SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell. 2006 Nov;11(5):697-709 |
1 | J:306384 Terrey M, Adamson SI, Chuang JH, Ackerman SL, Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology. Elife. 2021 Apr 26;10:e66904 |
1 | J:112694 Torban E, Dziarmaga A, Iglesias D, Chu LL, Vassilieva T, Little M, Eccles M, Discenza M, Pelletier J, Goodyer P, PAX2 activates WNT4 expression during mammalian kidney development. J Biol Chem. 2006 May 5;281(18):12705-12 |
1 | J:233479 Vong KI, Leung CK, Behringer RR, Kwan KM, Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum. Mol Brain. 2015;8:25 |
1 | J:316423 Whittaker DE, Oleari R, Gregory LC, Le Quesne-Stabej P, Williams HJ, Torpiano JG, Formosa N, Cachia MJ, Field D, Lettieri A, Ocaka LA, Paganoni AJ, Rajabali SH, Riegman KL, De Martini LB, Chaya T, Robinson IC, Furukawa T, Cariboni A, Basson MA, Dattani MT, A recessive PRDM13 mutation results in congenital hypogonadotropic hypogonadism and cerebellar hypoplasia. J Clin Invest. 2021 Dec 15;131(24):e141587 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
1 | J:201733 Xu Y, Lopes C, Wende H, Guo Z, Cheng L, Birchmeier C, Ma Q, Ontogeny of excitatory spinal neurons processing distinct somatic sensory modalities. J Neurosci. 2013 Sep 11;33(37):14738-48 |
Pax3 paired box 3 (Synonyms: Pax-3, Splchl2) | |
Results | Reference |
1 | J:103319 Horst D, Ustanina S, Sergi C, Mikuz G, Juergens H, Braun T, Vorobyov E, Comparative expression analysis of Pax3 and Pax7 during mouse myogenesis. Int J Dev Biol. 2006;50(1):47-54 |
1 | J:326543 Jiang A, Guo H, Jiang X, Tao J, Wu W, Liu H, G6PD Deficiency Is Crucial for Insulin Signaling Activation in Skeletal Muscle. Int J Mol Sci. 2022 Jul 4;23(13) |
1 | J:103257 Lacosta AM, Muniesa P, Ruberte J, Sarasa M, Dominguez L, Novel expression patterns of Pax3/Pax7 in early trunk neural crest and its melanocyte and non-melanocyte lineages in amniote embryos. Pigment Cell Res. 2005 Aug;18(4):243-51 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97 |
1* | J:206666 Parry DA, Logan CV, Stegmann AP, Abdelhamed ZA, Calder A, Khan S, Bonthron DT, Clowes V, Sheridan E, Ghali N, Chudley AE, Dobbie A, Stumpel CT, Johnson CA, SAMS, a syndrome of short stature, auditory-canal atresia, mandibular hypoplasia, and skeletal abnormalities is a unique neurocristopathy caused by mutations in Goosecoid. Am J Hum Genet. 2013 Dec 5;93(6):1135-42 |
1 | J:202131 Sakai H, Sato T, Sakurai H, Yamamoto T, Hanaoka K, Montarras D, Sehara-Fujisawa A, Fetal skeletal muscle progenitors have regenerative capacity after intramuscular engraftment in dystrophin deficient mice. PLoS One. 2013;8(5):e63016 |
1 | J:282590 Wei S, Du H, Li Z, Tao G, Xu Z, Song X, Shang Z, Su Z, Chen H, Wen Y, Liu G, You Y, Zhang Z, Yang Z, Transcription factors Sp8 and Sp9 regulate the development of caudal ganglionic eminence-derived cortical interneurons. J Comp Neurol. 2019 Dec 1;527(17):2860-2874 |
Pax4 paired box 4 (Synonyms: Pax-4) | |
Results | Reference |
1 | J:156329 Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L, Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. J Biol Chem. 2009 Nov 6;284(45):31236-48 |
1 | J:176201 Kordowich S, Collombat P, Mansouri A, Serup P, Arx and Nkx2.2 compound deficiency redirects pancreatic alpha- and beta-cell differentiation to a somatostatin/ghrelin co-expressing cell lineage. BMC Dev Biol. 2011;11:52 |
1* | J:39208 Sosa-Pineda B, Chowdhury K, Torres M, Oliver G, Gruss P, The Pax4 gene is essential for differentiation of insulin-producing beta cells in the mammalian pancreas. Nature. 1997 Mar 27;386(6623):399-402 |
1 | J:130423 Wang Q, Elghazi L, Martin S, Martins I, Srinivasan RS, Geng X, Sleeman M, Collombat P, Houghton J, Sosa-Pineda B, Ghrelin is a novel target of Pax4 in endocrine progenitors of the pancreas and duodenum. Dev Dyn. 2008 Jan;237(1):51-61 |
Pax5 paired box 5 (Synonyms: EBB-1, Pax-5) | |
Results | Reference |
1 | J:2251 Adams B, Dorfler P, Aguzzi A, Kozmik Z, Urbanek P, Maurer-Fogy I, Busslinger M, Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis. Genes Dev. 1992 Sep;6(9):1589-607 |
1 | J:358820 Dudukcu O, Raj DDA, van de Haar LL, Grossouw LM, Linders LE, Garritsen O, Adolfs Y, van Kronenburg NCH, Broekhoven MH, Kapteijns THW, Meye FJ, Pasterkamp RJ, Molecular diversity and migration of GABAergic neurons in the developing ventral midbrain. iScience. 2024 Nov 15;27(11):111239 |
1 | J:296045 Patmore DM, Jassim A, Nathan E, Gilbertson RJ, Tahan D, Hoffmann N, Tong Y, Smith KS, Kanneganti TD, Suzuki H, Taylor MD, Northcott P, Gilbertson RJ, DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma. Dev Cell. 2020 Aug 24;54(4):455-470.e5 |
1* | J:39856 Scott EW, Fisher RC, Olson MC, Kehrli EW, Simon MC, Singh H, PU.1 functions in a cell-autonomous manner to control the differentiation of multipotential lymphoid-myeloid progenitors. Immunity. 1997 Apr;6(4):437-47 |
Pax6 paired box 6 (Synonyms: 1500038E17Rik, AEY11, Dey, Dickie's small eye, Gsfaey11, Pax-6) | |
Results | Reference |
1 | J:353312 Adutwum-Ofosu K, Magnani D, Theil T, Price DJ, Fotaki, The molecular and cellular signatures of the mouse eminentia thalami support its role as a signalling centre in the developing forebrain. Brain Struct Funct. 2016;221(7):3709-27 |
1 | J:156329 Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L, Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. J Biol Chem. 2009 Nov 6;284(45):31236-48 |
1 | J:317549 Aryal S, Viet J, Weatherbee BAT, Siddam AD, Hernandez FG, Gautier-Courteille C, Paillard L, Lachke SA, The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development. Hum Genet. 2020 Dec;139(12):1541-1554 |
1 | J:299451 Atkins A, Xu MJ, Li M, Rogers NP, Pryzhkova MV, Jordan PW, SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. Elife. 2020 Nov 17;9:e61171 |
1* | J:181601 Bassett EA, Korol A, Deschamps PA, Buettner R, Wallace VA, Williams T, West-Mays JA, Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29 |
1 | J:284524 Bendriem RM, Singh S, Aleem AA, Antonetti DA, Ross ME, Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex. Elife. 2019 Dec 3;8:e49376 |
1 | J:305458 Bertacchi M, Romano AL, Loubat A, Tran Mau-Them F, Willems M, Faivre L, Khau van Kien P, Perrin L, Devillard F, Sorlin A, Kuentz P, Philippe C, Garde A, Neri F, Di Giaimo R, Oliviero S, Cappello S, D'Incerti L, Frassoni C, Studer M, NR2F1 regulates regional progenitor dynamics in the mouse neocortex and cortical gyrification in BBSOAS patients. EMBO J. 2020 Jul 1;39(13):e104163 |
1 | J:356256 Bertino F, Mukherjee D, Bonora M, Bagowski C, Nardelli J, Metani L, Zanin Venturini DI, Chianese D, Santander N, Salaroglio IC, Hentschel A, Quarta E, Genova T, McKinney AA, Allocco AL, Fiorito V, Petrillo S, Ammirata G, De Giorgio F, Dennis E, Allington G, Maier F, Shoukier M, Gloning KP, Munaron L, Mussano F, Salsano E, Pareyson D, di Rocco M, Altruda F, Panagiotakos G, Kahle KT, Gressens P, Riganti C, Pinton PP, Roos A, Arnold T, Tolosano E, Chiabrando D, Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus. Cell Rep Med. 2024 Jul 16;5(7):101647 |
1 | J:188155 Bharti K, Gasper M, Ou J, Brucato M, Clore-Gronenborn K, Pickel J, Arnheiter H, A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development. PLoS Genet. 2012 Jul;8(7):e1002757 |
1 | J:234630 Bonney S, Harrison-Uy S, Mishra S, MacPherson AM, Choe Y, Li D, Jaminet SC, Fruttiger M, Pleasure SJ, Siegenthaler JA, Diverse Functions of Retinoic Acid in Brain Vascular Development. J Neurosci. 2016 Jul 20;36(29):7786-801 |
1 | J:196836 Cammas L, Wolfe J, Choi SY, Dedhar S, Beggs HE, Integrin-linked kinase deletion in the developing lens leads to capsule rupture, impaired fiber migration and non-apoptotic epithelial cell death. Invest Ophthalmol Vis Sci. 2012;53(6):3067-81 |
1 | J:228026 Capecchi MR, Pozner A, ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination. Nat Commun. 2015;6:8763 |
1 | J:182669 Cappello S, Bohringer CR, Bergami M, Conzelmann KK, Ghanem A, Tomassy GS, Arlotta P, Mainardi M, Allegra M, Caleo M, van Hengel J, Brakebusch C, Gotz M, A radial glia-specific role of RhoA in double cortex formation. Neuron. 2012 Mar 8;73(5):911-24 |
1 | J:313961 Caramello A, Galichet C, Rizzoti K, Lovell-Badge R, Dentate gyrus development requires a cortical hem-derived astrocytic scaffold. Elife. 2021 Jan 4;10:e63904 |
1 | J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5 |
1* | J:318768 Carpentieri JA, Di Cicco A, Lampic M, Andreau D, Del Maestro L, El Marjou F, Coquand L, Bahi-Buisson N, Brault JB, Baffet AD, Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly. Nat Commun. 2022 Jan 10;13(1):16 |
1 | J:346633 Cheng J, Wang Z, Tang M, Zhang W, Li G, Tan S, Mu C, Hu M, Zhang D, Jia X, Wen Y, Guo H, Xu D, Liu L, Li J, Xia K, Li F, Duan R, Xu Z, Yuan L, KCTD10 regulates brain development by destabilizing brain disorder-associated protein KCTD13. Proc Natl Acad Sci U S A. 2024 Mar 19;121(12):e2315707121 |
1 | J:333325 Cheng Q, Wu J, Xia Y, Cheng Q, Zhao Y, Zhu P, Zhang W, Zhang S, Zhang L, Yuan Y, Li C, Chen G, Xue B, Disruption of protein geranylgeranylation in the cerebellum causes cerebellar hypoplasia and ataxia via blocking granule cell progenitor proliferation. Mol Brain. 2023 Feb 13;16(1):24 |
1 | J:223109 Choi JJ, Ting CT, Trogrlic L, Milevski SV, Familari M, Martinez G, de Iongh RU, A role for smoothened during murine lens and cornea development. PLoS One. 2014;9(9):e108037 |
1 | J:346120 Cornejo F, Franchini N, Cortes BI, Elgueta D, Cancino GI, Neural conditional ablation of the protein tyrosine phosphatase receptor Delta PTPRD impairs gliogenesis in the developing mouse brain cortex. Front Cell Dev Biol. 2024;12:1357862 |
1* | J:242692 Coulthard LG, Hawksworth OA, Li R, Balachandran A, Lee JD, Sepehrband F, Kurniawan N, Jeanes A, Simmons DG, Wolvetang E, Woodruff TM, Complement C5aR1 Signaling Promotes Polarization and Proliferation of Embryonic Neural Progenitor Cells through PKCzeta. J Neurosci. 2017 May 31;37(22):5395-5407 |
1* | J:326932 Dai SK, Liu PP, Li X, Jiao LF, Teng ZQ, Liu CM, Dynamic profiling and functional interpretation of histone lysine crotonylation and lactylation during neural development. Development. 2022 Jul 15;149(14):dev200049 |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
1* | J:225905 Dash S, Dang CA, Beebe DC, Lachke SA, Deficiency of the RNA binding protein caprin2 causes lens defects and features of peters anomaly. Dev Dyn. 2015 Oct;244(10):1313-27 |
1 | J:206591 Di Giovannantonio LG, Di Salvio M, Omodei D, Prakash N, Wurst W, Pierani A, Acampora D, Simeone A, Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity. Development. 2014 Jan;141(2):377-88 |
1 | J:235557 Diaz-Alonso J, Aguado T, de Salas-Quiroga A, Ortega Z, Guzman M, Galve-Roperh I, CB1 Cannabinoid Receptor-Dependent Activation of mTORC1/Pax6 Signaling Drives Tbr2 Expression and Basal Progenitor Expansion in the Developing Mouse Cortex. Cereb Cortex. 2015 Sep;25(9):2395-408 |
1 | J:304642 Dupacova N, Antosova B, Paces J, Kozmik Z, Meis homeobox genes control progenitor competence in the retina. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2013136118 |
2 | J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109 |
1 | J:204473 Elso C, Lu X, Weisner PA, Thompson HL, Skinner A, Carver E, Stubbs L, A reciprocal translocation dissects roles of Pax6 alternative promoters and upstream regulatory elements in the development of pancreas, brain, and eye. Genesis. 2013 Sep;51(9):630-46 |
3 | J:54722 Engelkamp D, Rashbass P, Seawright A, van Heyningen V, Role of Pax6 in development of the cerebellar system. Development. 1999 Aug;126(16):3585-96 |
1 | J:95876 Englund C, Fink A, Lau C, Pham D, Daza RA, Bulfone A, Kowalczyk T, Hevner RF, Pax6, Tbr2, and Tbr1 are expressed sequentially by radial glia, intermediate progenitor cells, and postmitotic neurons in developing neocortex. J Neurosci. 2005 Jan 5;25(1):247-51 |
1 | J:112207 Englund C, Kowalczyk T, Daza RA, Dagan A, Lau C, Rose MF, Hevner RF, Unipolar brush cells of the cerebellum are produced in the rhombic lip and migrate through developing white matter. J Neurosci. 2006 Sep 6;26(36):9184-95 |
1 | J:172287 Esteve P, Sandonis A, Cardozo M, Malapeira J, Ibanez C, Crespo I, Marcos S, Gonzalez-Garcia S, Toribio ML, Arribas J, Shimono A, Guerrero I, Bovolenta P, SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis. Nat Neurosci. 2011 May;14(5):562-9 |
1* | J:73289 Estivill-Torrus G, Vitalis T, Fernandez-Llebrez P, Price DJ, The transcription factor Pax6 is required for development of the diencephalic dorsal midline secretory radial glia that form the subcommissural organ. Mech Dev. 2001 Dec;109(2):215-24 |
1 | J:104125 Evans AL, Gage PJ, Expression of the homeobox gene Pitx2 in neural crest is required for optic stalk and ocular anterior segment development. Hum Mol Genet. 2005 Nov 15;14(22):3347-59 |
1 | J:218288 Falcone C, Filippis C, Granzotto M, Mallamaci A, Emx2 expression levels in NSCs modulate astrogenesis rates by regulating EgfR and Fgf9. Glia. 2015 Mar;63(3):412-22 |
1 | J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489 |
1 | J:211816 Fei JF, Haffner C, Huttner WB, 3' UTR-dependent, miR-92-mediated restriction of Tis21 expression maintains asymmetric neural stem cell division to ensure proper neocortex size. Cell Rep. 2014 Apr 24;7(2):398-411 |
1 | J:250440 Ferguson R, Serafeimidou-Pouliou E, Subramanian V, Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation. J Anat. 2016 Dec;229(6):871-891 |
1 | J:184924 Fernandes M, Antoine M, Hebert JM, SMAD4 is essential for generating subtypes of neurons during cerebellar development. Dev Biol. 2012 May 1;365(1):82-90 |
1* | J:278498 Friocourt F, Kozulin P, Belle M, Suarez R, Di-Poi N, Richards LJ, Giacobini P, Chedotal A, Shared and differential features of Robo3 expression pattern in amniotes. J Comp Neurol. 2019 Aug 15;527(12):2009-2029 |
1 | J:323615 Fu Y, Zhou Y, Zhang YL, Zhao B, Zhang XL, Zhang WT, Lu YJ, Lu A, Zhang J, Zhang J, Loss of neurodevelopmental-associated miR-592 impairs neurogenesis and causes social interaction deficits. Cell Death Dis. 2022 Apr 1;13(4):292 |
1* | J:136041 Gage PJ, Qian M, Wu D, Rosenberg KI, The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development. Dev Biol. 2008 May 1;317(1):310-24 |
1 | J:206763 Gan Q, Lee A, Suzuki R, Yamagami T, Stokes A, Nguyen BC, Pleasure D, Wang J, Chen HW, Zhou CJ, Pax6 mediates ss-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells. Stem Cells. 2014 Jan;32(1):45-58 |
1 | J:246663 Garg A, Bansal M, Gotoh N, Feng GS, Zhong J, Wang F, Kariminejad A, Brooks S, Zhang X, Alx4 relays sequential FGF signaling to induce lacrimal gland morphogenesis. PLoS Genet. 2017 Oct;13(10):e1007047 |
2 | J:217584 Gerstmann K, Pensold D, Symmank J, Khundadze M, Hubner CA, Bolz J, Zimmer G, Thalamic afferents influence cortical progenitors via ephrin A5-EphA4 interactions. Development. 2015 Jan 1;142(1):140-50 |
1 | J:167212 Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ, Subtypes of medulloblastoma have distinct developmental origins. Nature. 2010 Dec 23;468(7327):1095-9 |
1 | J:215584 Gil-Sanz C, Landeira B, Ramos C, Costa MR, Muller U, Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon. J Neurosci. 2014 Aug 6;34(32):10475-87 |
1 | J:151321 Glickstein SB, Monaghan JA, Koeller HB, Jones TK, Ross ME, Cyclin D2 is critical for intermediate progenitor cell proliferation in the embryonic cortex. J Neurosci. 2009 Jul 29;29(30):9614-24 |
1* | J:51429 Gotz M, Stoykova A, Gruss P, Pax6 controls radial glia differentiation in the cerebral cortex. Neuron. 1998 Nov;21(5):1031-44 |
1* | J:191140 Grigoryan M, Kedees MH, Guz Y, Teitelman G, Phenotype of entero-endocrine L cells becomes restricted during development. Dev Dyn. 2012 Dec;241(12):1986-92 |
2 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:239666 Hagglund AC, Jones I, Carlsson L, A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development. Dis Model Mech. 2017 Mar 01;10(3):245-257 |
1 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
1 | J:259186 Heng X, Guo Q, Leung AW, Li JY, Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6:e23253 |
1 | J:226611 Hillmer RE, Boisvert JP, Cucciare MJ, Dwinell MB, Joksimovic M, Generation and characterization of mice harboring a conditional CXCL12 allele. Int J Dev Biol. 2015;59(4-6):205-9 |
1 | J:253242 Hu XL, Chen G, Zhang S, Zheng J, Wu J, Bai QR, Wang Y, Li J, Wang H, Feng H, Li J, Sun X, Xia Q, Yang F, Hang J, Qi C, Phoenix TN, Temple S, Shen Q, Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells. Neuron. 2017 Jul 19;95(2):309-325.e6 |
1* | J:283394 Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S, Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162 |
1* | J:171479 Hutton SR, Pevny LH, SOX2 expression levels distinguish between neural progenitor populations of the developing dorsal telencephalon. Dev Biol. 2011 Apr 1;352(1):40-7 |
1 | J:217499 Iwashita M, Kataoka N, Toida K, Kosodo Y, Systematic profiling of spatiotemporal tissue and cellular stiffness in the developing brain. Development. 2014 Oct;141(19):3793-8 |
1 | J:205043 Janisch KM, Vock VM, Fleming MS, Shrestha A, Grimsley-Myers CM, Rasoul BA, Neale SA, Cupp TD, Kinchen JM, Liem KF Jr, Dwyer ND, The vertebrate-specific Kinesin-6, Kif20b, is required for normal cytokinesis of polarized cortical stem cells and cerebral cortex size. Development. 2013 Dec;140(23):4672-82 |
1 | J:334107 Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J, Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice. Hum Mol Genet. 2022 Oct 10;31(20):3504-3520 |
1 | J:160411 Joo JH, Kim YH, Dunn NW, Sugrue SP, Disruption of mouse corneal epithelial differentiation by conditional inactivation of pnn. Invest Ophthalmol Vis Sci. 2010 Apr;51(4):1927-34 |
1 | J:314290 Kanemitsu Y, Fujitani M, Fujita Y, Zhang S, Su YQ, Kawahara Y, Yamashita T, The RNA-binding protein MARF1 promotes cortical neurogenesis through its RNase activity domain. Sci Rep. 2017 Apr 25;7(1):1155 |
1 | J:249035 Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M, McGillewie L, Bar S, Minocha S, Chevalier C, Po C, Chelly J, Mandel JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, Herault Y, Collins SC, Friant S, Godin JD, Yalcin B, WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9308-E9317 |
1 | J:209564 Karaca E, Weitzer S, Pehlivan D, Shiraishi H, Gogakos T, Hanada T, Jhangiani SN, Wiszniewski W, Withers M, Campbell IM, Erdin S, Isikay S, Franco LM, Gonzaga-Jauregui C, Gambin T, Gelowani V, Hunter JV, Yesil G, Koparir E, Yilmaz S, Brown M, Briskin D, Hafner M, Morozov P, Farazi TA, Bernreuther C, Glatzel M, Trattnig S, Friske J, Kronnerwetter C, Bainbridge MN, Gezdirici A, Seven M, Muzny DM, Boerwinkle E, Ozen M, Clausen T, Tuschl T, Yuksel A, Hess A, Gibbs RA, Martinez J, Penninger JM, Lupski JR, Human CLP1 mutations alter tRNA biogenesis, affecting both peripheral and central nervous system function. Cell. 2014 Apr 24;157(3):636-50 |
1 | J:356145 Khouri-Farah N, Guo Q, Morgan K, Shin J, Li JYH, Integrated single-cell transcriptomic and epigenetic study of cell state transition and lineage commitment in embryonic mouse cerebellum. Sci Adv. 2022 Apr;8(13):eabl9156 |
1 | J:234375 Kim H, Jang WY, Kang MC, Jeong J, Choi M, Sung Y, Park S, Kwon W, Jang S, Kim MO, Kim SH, Ryoo ZY, TET1 contributes to neurogenesis onset time during fetal brain development in mice. Biochem Biophys Res Commun. 2016 Mar 18;471(4):437-43 |
1 | J:168981 Kim JJ, Gill PS, Rotin L, van Eede M, Henkelman RM, Hui CC, Rosenblum ND, Suppressor of Fused Controls Mid-Hindbrain Patterning and Cerebellar Morphogenesis via GLI3 Repressor. J Neurosci. 2011 Feb 2;31(5):1825-36 |
1* | J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347 |
1 | J:222255 Knock E, Pereira J, Lombard PD, Dimond A, Leaford D, Livesey FJ, Hendrich B, The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex. Neural Dev. 2015;10:13 |
1 | J:176201 Kordowich S, Collombat P, Mansouri A, Serup P, Arx and Nkx2.2 compound deficiency redirects pancreatic alpha- and beta-cell differentiation to a somatostatin/ghrelin co-expressing cell lineage. BMC Dev Biol. 2011;11:52 |
1* | J:163966 Kowalczyk T, Pontious A, Englund C, Daza RA, Bedogni F, Hodge R, Attardo A, Bell C, Huttner WB, Hevner RF, Intermediate neuronal progenitors (basal progenitors) produce pyramidal-projection neurons for all layers of cerebral cortex. Cereb Cortex. 2009 Oct;19(10):2439-50 |
1 | J:158681 Kuwahara A, Hirabayashi Y, Knoepfler PS, Taketo MM, Sakai J, Kodama T, Gotoh Y, Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex. Development. 2010 Apr;137(7):1035-44 |
1 | J:163240 Kuwako K, Kakumoto K, Imai T, Igarashi M, Hamakubo T, Sakakibara S, Tessier-Lavigne M, Okano HJ, Okano H, Neural RNA-binding protein Musashi1 controls midline crossing of precerebellar neurons through posttranscriptional regulation of Robo3/Rig-1 expression. Neuron. 2010 Aug 12;67(3):407-21 |
1 | J:254235 Lanctot AA, Guo Y, Le Y, Edens BM, Nowakowski RS, Feng Y, Loss of Brap Results in Premature G1/S Phase Transition and Impeded Neural Progenitor Differentiation. Cell Rep. 2017 Aug 1;20(5):1148-1160 |
1 | J:317151 Lavado A, Gangwar R, Pare J, Wan S, Fan Y, Cao X, YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development. Dev Biol. 2021 Dec;480:39-49 |
1* | J:199301 Lavado A, He Y, Pare J, Neale G, Olson EN, Giovannini M, Cao X, Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators. Development. 2013 Aug;140(16):3323-34 |
1 | J:332919 Leca I, Phillips AW, Ushakova L, Cushion TD, Keays DA, Codon modification of Tuba1a alters mRNA levels and causes a severe neurodevelopmental phenotype in mice. Sci Rep. 2023 Jan 21;13(1):1215 |
1 | J:205567 Li K, Leung AW, Guo Q, Yang W, Li JY, Shp2-Dependent ERK Signaling Is Essential for Induction of Bergmann Glia and Foliation of the Cerebellum. J Neurosci. 2014 Jan 15;34(3):922-31 |
2* | J:294282 Li L, Ruan X, Wen C, Chen P, Liu W, Zhu L, Xiang P, Zhang X, Wei Q, Hou L, Yin B, Yuan J, Qiang B, Shu P, Peng X, The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019 Jul 16;28(3):698-711.e5 |
1 | J:328234 Li Y, Fan T, Li X, Liu L, Mao F, Li Y, Miao Z, Zeng C, Song W, Pan J, Zhou S, Wang H, Wang Y, Sun ZS, Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors. Cell Rep. 2022 Aug 30;40(9):111289 |
1* | J:151925 Li Y, Piatigorsky J, Targeted deletion of Dicer disrupts lens morphogenesis, corneal epithelium stratification, and whole eye development. Dev Dyn. 2009 Sep;238(9):2388-400 |
2* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1 | J:295031 Li Z, Pratt T, Price DJ, Zic4-Lineage Cells Increase Their Contribution to Visual Thalamic Nuclei during Murine Embryogenesis If They Are Homozygous or Heterozygous for Loss of Pax6 Function. eNeuro. 2018 Sep-Oct;5(5):ENEURO.0367-18.2018 |
1 | J:348634 Lin L, Zhao J, Kubota N, Li Z, Lam YL, Nguyen LP, Yang L, Pokharel SP, Blue SM, Yee BA, Chen R, Yeo GW, Chen CW, Chen L, Zheng S, Epistatic interactions between NMD and TRP53 control progenitor cell maintenance and brain size. Neuron. 2024 Apr 22; |
1 | J:292113 Lin YN, Lee YS, Li SK, Tang TK, Loss of CPAP in developing mouse brain and its functional implication for human primary microcephaly. J Cell Sci. 2020 Jun 24;133(12):jcs243592 |
1 | J:272578 Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G, Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. Dev Cell. 2019 Jan 7;48(1):49-63.e7 |
1* | J:91057 Louvi A, Sisodia SS, Grove EA, Presenilin 1 in migration and morphogenesis in the central nervous system. Development. 2004 Jul;131(13):3093-105 |
1 | J:240674 Lu HC, Tan Q, Rousseaux MW, Wang W, Kim JY, Richman R, Wan YW, Yeh SY, Patel JM, Liu X, Lin T, Lee Y, Fryer JD, Han J, Chahrour M, Finnell RH, Lei Y, Zurita-Jimenez ME, Ahimaz P, Anyane-Yeboa K, Van Maldergem L, Lehalle D, Jean-Marcais N, Mosca-Boidron AL, Thevenon J, Cousin MA, Bro DE, Lanpher BC, Klee EW, Alexander N, Bainbridge MN, Orr HT, Sillitoe RV, Ljungberg MC, Liu Z, Schaaf CP, Zoghbi HY, Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nat Genet. 2017 Apr;49(4):527-536 |
2 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
1 | J:179730 Mairet-Coello G, Tury A, Van Buskirk E, Robinson K, Genestine M, Dicicco-Bloom E, p57KIP2 regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortex. Development. 2012 Feb;139(3):475-87 |
1 | J:328992 Manuel M, Tan KB, Kozic Z, Molinek M, Marcos TS, Razak MFA, Dobolyi D, Dobie R, Henderson BEP, Henderson NC, Chan WK, Daw MI, Mason JO, Price DJ, Pax6 limits the competence of developing cerebral cortical cells to respond to inductive intercellular signals. PLoS Biol. 2022 Sep;20(9):e3001563 |
1 | J:91469 Marillat V, Sabatier C, Failli V, Matsunaga E, Sotelo C, Tessier-Lavigne M, Chedotal A, The slit receptor Rig-1/Robo3 controls midline crossing by hindbrain precerebellar neurons and axons. Neuron. 2004 Jul 8;43(1):69-79 |
1 | J:341276 Matrongolo MJ, Ho-Nguyen KT, Jain M, Ang PS, Reddy A, Schaper S, Tischfield MA, Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice. Development. 2023 Sep 15;150(18):dev201381 |
1 | J:286398 Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, Furuse T, Shibuya H, Yasuda Y, Yamamori H, Fujimoto M, Nagayasu K, Yamamoto K, Kitagawa K, Miura H, Gotoda-Nishimura N, Igarashi H, Hayashida M, Baba M, Kondo M, Hasebe S, Ueshima K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Iguchi T, Sato M, Yamaguchi S, Tamura M, Wakana S, Yoshiki A, Watabe AM, Okano H, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T, Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes. Nat Commun. 2020 Feb 26;11(1):859 |
2 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
1* | J:231957 McEntagart M, Williamson KA, Rainger JK, Wheeler A, Seawright A, De Baere E, Verdin H, Bergendahl LT, Quigley A, Rainger J, Dixit A, Sarkar A, Lopez Laso E, Sanchez-Carpintero R, Barrio J, Bitoun P, Prescott T, Riise R, McKee S, Cook J, McKie L, Ceulemans B, Meire F, Temple IK, Prieur F, Williams J, Clouston P, Nemeth AH, Banka S, Bengani H, Handley M, Freyer E, Ross A, van Heyningen V, Marsh JA, Elmslie F, FitzPatrick DR, A Restricted Repertoire of De Novo Mutations in ITPR1 Cause Gillespie Syndrome with Evidence for Dominant-Negative Effect. Am J Hum Genet. 2016 May 5;98(5):981-92 |
1 | J:214970 Mecklenburg N, Martinez-Lopez JE, Moreno-Bravo JA, Perez-Balaguer A, Puelles E, Martinez S, Growth and differentiation factor 10 (Gdf10) is involved in Bergmann glial cell development under Shh regulation. Glia. 2014 Oct;62(10):1713-23 |
1 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
1 | J:123317 Miyoshi G, Butt SJ, Takebayashi H, Fishell G, Physiologically distinct temporal cohorts of cortical interneurons arise from telencephalic Olig2-expressing precursors. J Neurosci. 2007 Jul 18;27(29):7786-98 |
1 | J:341495 Mizukoshi T, Yamada S, Sakakibara SI, Spatiotemporal Regulation of De Novo and Salvage Purine Synthesis during Brain Development. eNeuro. 2023 Oct;10(10):ENEURO.0159-23.2023 |
1 | J:331478 Monko T, Rebertus J, Stolley J, Salton SR, Nakagawa Y, Thalamocortical axons regulate neurogenesis and laminar fates in the early sensory cortex. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2201355119 |
1 | J:346596 Mubuchi A, Takechi M, Nishio S, Matsuda T, Itoh Y, Sato C, Kitajima K, Kitagawa H, Miyata S, Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons. Elife. 2024 Mar 21;12 |
1 | J:335191 Munz M, Bharioke A, Kosche G, Moreno-Juan V, Brignall A, Rodrigues TM, Graff-Meyer A, Ulmer T, Haeuselmann S, Pavlinic D, Ledergerber N, Gross-Scherf B, Rozsa B, Krol J, Picelli S, Cowan CS, Roska B, Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex. Cell. 2023 Apr 27;186(9):1930-1949.e31 |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
1 | J:309437 Nakagawa N, Li J, Yabuno-Nakagawa K, Eom TY, Cowles M, Mapp T, Taylor R, Anton ES, APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017 Aug 15;31(16):1679-1692 |
2* | J:68840 Nakagawa Y, O'Leary DD, Combinatorial expression patterns of LIM-homeodomain and other regulatory genes parcellate developing thalamus. J Neurosci. 2001 Apr 15;21(8):2711-25 |
1 | J:330740 Narayanan R, Pham L, Kerimoglu C, Watanabe T, Castro Hernandez R, Sokpor G, Ulmke PA, Kiszka KA, Tonchev AB, Rosenbusch J, Seong RH, Teichmann U, Frahm J, Fischer A, Bonn S, Stoykova A, Staiger JF, Tuoc T, Chromatin Remodeling BAF155 Subunit Regulates the Genesis of Basal Progenitors in Developing Cortex. iScience. 2018 Jun 29;4:109-126 |
1 | J:171288 Nishida K, Nakayama K, Yoshimura S, Murakami F, Role of Neph2 in pontine nuclei formation in the developing hindbrain. Mol Cell Neurosci. 2011 Mar;46(3):662-70 |
1 | J:240892 Nitarska J, Smith JG, Sherlock WT, Hillege MM, Nott A, Barshop WD, Vashisht AA, Wohlschlegel JA, Mitter R, Riccio A, A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development. Cell Rep. 2016 Nov 01;17(6):1683-1698 |
1 | J:285050 Ochi S, Imaizumi Y, Shimojo H, Miyachi H, Kageyama R, Oscillatory expression of Hes1 regulates cell proliferation and neuronal differentiation in the embryonic brain. Development. 2020 Feb 26;147(4):dev182204 |
1 | J:150768 Okado H, Ohtaka-Maruyama C, Sugitani Y, Fukuda Y, Ishida R, Hirai S, Miwa A, Takahashi A, Aoki K, Mochida K, Suzuki O, Honda T, Nakajima K, Ogawa M, Terashima T, Matsuda J, Kawano H, Kasai M, The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Dev Biol. 2009 Jul 15;331(2):140-51 |
1 | J:206963 Orieux G, Picault L, Slembrouck A, Roger JE, Guillonneau X, Sahel JA, Saule S, McPherson JP, Goureau O, Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells. J Neurosci. 2014 Jan 22;34(4):1530-41 |
1 | J:142509 Oron-Karni V, Farhy C, Elgart M, Marquardt T, Remizova L, Yaron O, Xie Q, Cvekl A, Ashery-Padan R, Dual requirement for Pax6 in retinal progenitor cells. Development. 2008 Dec;135(24):4037-47 |
1 | J:230288 Oshiro H, Hirabayashi Y, Furuta Y, Okabe S, Gotoh Y, Up-regulation of HP1gamma expression during neuronal maturation promotes axonal and dendritic development in mouse embryonic neocortex. Genes Cells. 2015 Feb;20(2):108-20 |
1 | J:257543 Owa T, Taya S, Miyashita S, Yamashita M, Adachi T, Yamada K, Yokoyama M, Aida S, Nishioka T, Inoue YU, Goitsuka R, Nakamura T, Inoue T, Kaibuchi K, Hoshino M, Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation. J Neurosci. 2018 Jan 31;38(5):1277-1294 |
1 | J:331057 Parichha A, Datta D, Suresh V, Chatterjee M, Holtzman MJ, Tole S, Dentate gyrus morphogenesis is regulated by beta-catenin function in hem-derived fimbrial glia. Development. 2022 Nov 1;149(21):dev200953 |
1 | J:320719 Parichha A, Suresh V, Chatterjee M, Kshirsagar A, Ben-Reuven L, Olender T, Taketo MM, Radosevic V, Bobic-Rasonja M, Trnski S, Holtzman MJ, Jovanov-Milosevic N, Reiner O, Tole S, Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate. Nat Commun. 2022 Feb 2;13(1):633 |
1* | J:185947 Parisi I, Collinson JM, Regulation of Merkel cell development by Pax6. Int J Dev Biol. 2012;56(5):341-50 |
1 | J:241853 Parisot J, Flore G, Bertacchi M, Studer M, COUP-TFI mitotically regulates production and migration of dentate granule cells and modulates hippocampal Cxcr4 expression. Development. 2017 Jun 01;144(11):2045-2058 |
1 | J:287008 Pearson CA, Moore DM, Tucker HO, Dekker JD, Hu H, Miquelajauregui A, Novitch BG, Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates. Cell Rep. 2020 Feb 11;30(6):1964-1981.e3 |
1* | J:103471 Pinson J, Mason JO, Simpson TI, Price DJ, Regulation of the Pax6 : Pax6(5a) mRNA ratio in the developing mammalian brain. BMC Dev Biol. 2005 Jul 19;5:13 |
1 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:302610 Puelles L, Diaz C, Stuhmer T, Ferran JL, Martinez-de la Torre M, Rubenstein JLR, LacZ-reporter mapping of Dlx5/6 expression and genoarchitectural analysis of the postnatal mouse prethalamus. J Comp Neurol. 2021 Feb;529(2):367-420 |
1 | J:236865 Ramesh V, Bayam E, Cernilogar FM, Bonapace IM, Schulze M, Riemenschneider MJ, Schotta G, Gotz M, Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration. Genes Dev. 2016 Oct 1;30(19):2199-2212 |
1* | J:332883 Rastegar-Pouyani S, Kennedy TE, Kania A, Somatotopy of Mouse Spinothalamic Innervation and the Localization of a Noxious Stimulus Requires Deleted in Colorectal Carcinoma Expression by Phox2a Neurons. J Neurosci. 2022 Oct 19;42(42):7885-7899 |
1 | J:287604 Ratie L, Desmaris E, Garcia-Moreno F, Hoerder-Suabedissen A, Kelman A, Theil T, Bellefroid EJ, Molnar Z, Loss of Dmrt5 Affects the Formation of the Subplate and Early Corticogenesis. Cereb Cortex. 2020 May 14;30(5):3296-3312 |
1* | J:292351 Rodrigues DC, Harvey EM, Suraj R, Erickson SL, Mohammad L, Ren M, Liu H, He G, Kaplan DR, Ellis J, Yang G, Methylglyoxal couples metabolic and translational control of Notch signalling in mammalian neural stem cells. Nat Commun. 2020 Apr 24;11(1):2018 |
1 | J:220958 Rosenthal EH, Tonchev AB, Stoykova A, Chowdhury K, Regulation of archicortical arealization by the transcription factor Zbtb20. Hippocampus. 2012 Nov;22(11):2144-56 |
1 | J:353313 Roussat M, Jungas T, Audouard C, Omerani S, Medevielle F, Agius E, Davy A, Pituello F, Bel-Vialar S, Control of G(2) Phase Duration by CDC25B Modulates the Switch from Direct to Indirect Neurogenesis in the Neocortex. J Neurosci. 2023 Feb 15;43(7):1154-1165 |
1 | J:109774 Roy K, Kuznicki K, Wu Q, Sun Z, Bock D, Schutz G, Vranich N, Monaghan AP, The Tlx gene regulates the timing of neurogenesis in the cortex. J Neurosci. 2004 Sep 22;24(38):8333-45 |
1 | J:168545 Saffary R, Xie Z, FMRP Regulates the Transition from Radial Glial Cells to Intermediate Progenitor Cells during Neocortical Development. J Neurosci. 2011 Jan 26;31(4):1427-39 |
1 | J:341708 Saha S, Jungas TT, Ohayon D, Audouard C, Ye T, Fawal MA, Davy A, Dihydrofolate reductase activity controls neurogenic transitions in the developing neocortex. Development. 2023 Oct 15;150(20):dev201696 |
2 | J:125013 Schmid T, Kruger M, Braun T, NSCL-1 and -2 control the formation of precerebellar nuclei by orchestrating the migration of neuronal precursor cells. J Neurochem. 2007 Sep;102(6):2061-72 |
1 | J:305768 Selvadurai HJ, Luis E, Desai K, Lan X, Vladoiu MC, Whitley O, Galvin C, Vanner RJ, Lee L, Whetstone H, Kushida M, Nowakowski T, Diamandis P, Hawkins C, Bader G, Kriegstein A, Taylor MD, Dirks PB, Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2(+) Granule Neuron Precursor. Cell Rep. 2020 Apr 14;31(2):107511 |
2 | J:195711 Shi F, Fan Y, Zhang L, Meng L, Zhi H, Hu H, Lin A, The expression of Pax6 variants is subject to posttranscriptional regulation in the developing mouse eyelid. PLoS One. 2013;8(1):e53919 |
1 | J:213479 Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, Yoshida N, PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Cereb Cortex. 2013 Aug;23(8):1824-35 |
1 | J:270726 Shimada IS, Hwang SH, Somatilaka BN, Wang X, Skowron P, Kim J, Kim M, Shelton JM, Rajaram V, Xuan Z, Taylor MD, Mukhopadhyay S, Basal Suppression of the Sonic Hedgehog Pathway by the G-Protein-Coupled Receptor Gpr161 Restricts Medulloblastoma Pathogenesis. Cell Rep. 2018 Jan 30;22(5):1169-1184 |
1* | J:275368 Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, Zeng Y, Fu H, Wang M, Chen P, Zhang X, Yin B, Yuan J, Qiang B, Peng X, The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019 Mar 8;294(10):3444-3453 |
1 | J:283783 Shu P, Wu C, Ruan X, Liu W, Hou L, Fu H, Wang M, Liu C, Zeng Y, Chen P, Yin B, Yuan J, Qiang B, Peng X, Zhong W, Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell. 2019 Jun 3;49(5):764-785.e4 |
1 | J:159625 Silver DL, Watkins-Chow DE, Schreck KC, Pierfelice TJ, Larson DM, Burnetti AJ, Liaw HJ, Myung K, Walsh CA, Gaiano N, Pavan WJ, The exon junction complex component Magoh controls brain size by regulating neural stem cell division. Nat Neurosci. 2010 May;13(5):551-8 |
1 | J:122566 Simirskii VN, Wang Y, Duncan MK, Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype. Dev Biol. 2007 Jun 15;306(2):658-68 |
1 | J:206876 Song JY, Park R, Kim JY, Hughes L, Lu L, Kim S, Johnson RL, Cho SH, Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev Biol. 2014 Feb 15;386(2):281-90 |
1 | J:198821 Sparmann A, Xie Y, Verhoeven E, Vermeulen M, Lancini C, Gargiulo G, Hulsman D, Mann M, Knoblich JA, van Lohuizen M, The chromodomain helicase Chd4 is required for Polycomb-mediated inhibition of astroglial differentiation. EMBO J. 2013 May 29;32(11):1598-612 |
1* | J:324710 Stanton-Turcotte D, Hsu K, Moore SA, Yamada M, Fawcett JP, Iulianella A, Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development. J Neurosci. 2022 May 11;42(19):3931-3948 |
1 | J:159839 Stevens HE, Smith KM, Maragnoli ME, Fagel D, Borok E, Shanabrough M, Horvath TL, Vaccarino FM, Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits. J Neurosci. 2010 Apr 21;30(16):5590-602 |
1* | J:65195 Stoykova A, Treichel D, Hallonet M, Gruss P, Pax6 modulates the dorsoventral patterning of the mammalian telencephalon. J Neurosci. 2000 Nov 1;20(21):8042-50 |
1 | J:160871 Sudarov A, Joyner AL, Cerebellum morphogenesis: the foliation pattern is orchestrated by multi-cellular anchoring centers. Neural Dev. 2007;2:26 |
1* | J:203065 Sugiyama T, Osumi N, Katsuyama Y, The germinal matrices in the developing dentate gyrus are composed of neuronal progenitors at distinct differentiation stages. Dev Dyn. 2013 Dec;242(12):1442-53 |
1 | J:343554 Sun Q, Li J, Ma J, Zheng Y, Ju R, Li X, Ren X, Huang L, Chen R, Tan X, Luo L, JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development. Invest Ophthalmol Vis Sci. 2023 Dec 1;64(15):15 |
1 | J:320749 Sun YY, Chen WJ, Huang ZP, Yang G, Wu ML, Xu DE, Yang WL, Luo YC, Xiao ZC, Xu RX, Ma QH, TRIM32 Deficiency Impairs the Generation of Pyramidal Neurons in Developing Cerebral Cortex. Cells. 2022 Jan 28;11(3) |
1 | J:172723 Szabo NE, Zhao T, Cankaya M, Stoykova A, Zhou X, Alvarez-Bolado G, Interaction between Axons and Specific Populations of Surrounding Cells Is Indispensable for Collateral Formation in the Mammillary System. PLoS One. 2011;6(5):e20315 |
1 | J:278287 Tang T, Zhang Y, Wang Y, Cai Z, Lu Z, Li L, Huang R, Hagelkruys A, Matthias P, Zhang H, Seiser C, Xie Y, HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development. Neuron. 2019 Mar 20;101(6):1117-1133.e5 |
1 | J:287102 Tedeschi A, Almagro J, Renshaw MJ, Messal HA, Behrens A, Petronczki M, Cep55 promotes cytokinesis of neural progenitors but is dispensable for most mammalian cell divisions. Nat Commun. 2020 Apr 8;11(1):1746 |
1 | J:191783 Teissier A, Waclaw RR, Griveau A, Campbell K, Pierani A, Tangentially migrating transient glutamatergic neurons control neurogenesis and maintenance of cerebral cortical progenitor pools. Cereb Cortex. 2012 Feb;22(2):403-16 |
1 | J:154456 Thompson H, Andrews W, Parnavelas JG, Erskine L, Robo2 is required for Slit-mediated intraretinal axon guidance. Dev Biol. 2009 Nov 15;335(2):418-26 |
1* | J:104160 Tole S, Gutin G, Bhatnagar L, Remedios R, Hebert JM, Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev Biol. 2006 Jan 1;289(1):141-51 |
1 | J:98620 Tole S, Remedios R, Saha B, Stoykova A, Selective requirement of Pax6, but not Emx2, in the specification and development of several nuclei of the amygdaloid complex. J Neurosci. 2005 Mar 9;25(10):2753-60 |
1 | J:333324 Tominaga K, Sakashita E, Kasashima K, Kuroiwa K, Nagao Y, Iwamori N, Endo H, Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells. Int J Mol Sci. 2023 Jan 20;24(3) |
1 | J:279607 Tonchev AB, Tuoc TC, Rosenthal EH, Studer M, Stoykova A, Zbtb20 modulates the sequential generation of neuronal layers in developing cortex. Mol Brain. 2016 Jun 9;9(1):65 |
1* | J:72724 Toresson H, Campbell K, A role for Gsh1 in the developing striatum and olfactory bulb of Gsh2 mutant mice. Development. 2001 Dec;128(23):4769-80 |
2* | J:64588 Toresson H, Potter SS, Campbell K, Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for pax6 and gsh2. Development. 2000 Oct;127(20):4361-71 |
1 | J:268904 Tripathy R, Leca I, van Dijk T, Weiss J, van Bon BW, Sergaki MC, Gstrein T, Breuss M, Tian G, Bahi-Buisson N, Paciorkowski AR, Pagnamenta AT, Wenninger-Weinzierl A, Martinez-Reza MF, Landler L, Lise S, Taylor JC, Terrone G, Vitiello G, Del Giudice E, Brunetti-Pierri N, D'Amico A, Reymond A, Voisin N, Bernstein JA, Farrelly E, Kini U, Leonard TA, Valence S, Burglen L, Armstrong L, Hiatt SM, Cooper GM, Aldinger KA, Dobyns WB, Mirzaa G, Pierson TM, Baas F, Chelly J, Cowan NJ, Keays DA, Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations. Neuron. 2018 Dec 19;100(6):1354-1368.e5 |
1 | J:150808 Tuoc TC, Radyushkin K, Tonchev AB, Pinon MC, Ashery-Padan R, Molnar Z, Davidoff MS, Stoykova A, Selective cortical layering abnormalities and behavioral deficits in cortex-specific Pax6 knock-out mice. J Neurosci. 2009 Jul 1;29(26):8335-49 |
1 | J:304564 Venkataramanappa S, Schutz D, Saaber F, Kumar PA, Abe P, Schulz S, Stumm R, The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS Genet. 2021 Mar;17(3):e1009441 |
1 | J:64211 Vitalis T, Cases O, Engelkamp D, Verney C, Price DJ, Defect of tyrosine hydroxylase-immunoreactive neurons in the brains of mice lacking the transcription factor Pax6. J Neurosci. 2000 Sep 1;20(17):6501-16 |
1 | J:221658 Vithayathil J, Pucilowska J, Goodnough LH, Atit RP, Landreth GE, Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation. J Neurosci. 2015 Apr 29;35(17):6836-48 |
1 | J:233479 Vong KI, Leung CK, Behringer RR, Kwan KM, Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum. Mol Brain. 2015;8:25 |
1 | J:107576 Waclaw RR, Allen ZJ 2nd, Bell SM, Erdelyi F, Szabo G, Potter SS, Campbell K, The zinc finger transcription factor Sp8 regulates the generation and diversity of olfactory bulb interneurons. Neuron. 2006 Feb 16;49(4):503-16 |
1* | J:1914 Walther C, Gruss P, Pax-6, a murine paired box gene, is expressed in the developing CNS. Development. 1991 Dec;113(4):1435-49 |
2* | J:316179 Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y, An epigenetic circuit controls neurogenic programs during neocortex development. Development. 2021;148:dev199772 |
1 | J:303486 Wang J, Li T, Wang JL, Xu Z, Meng W, Wu QF, Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions. Cell Rep. 2020 Dec 15;33(11):108495 |
1 | J:339243 Wang J, Wang A, Tian K, Hua X, Zhang B, Zheng Y, Kong X, Li W, Xu L, Wang J, Li Z, Liu Y, Zhou Y, A Ctnnb1 enhancer regulates neocortical neurogenesis by controlling the abundance of intermediate progenitors. Cell Discov. 2022 Aug 2;8(1):74 |
1 | J:363654 Wang J, Zhang J, Li J, Gao Q, Chen J, Jia C, Gu X, Cortex-Specific Tmem169 Deficiency Induces Defects in Cortical Neuron Development and Autism-Like Behaviors in Mice. J Neurosci. 2025 Feb 26;45(9) |
1 | J:238248 Wang L, Hou S, Han YG, Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex. Nat Neurosci. 2016 Jul;19(7):888-96 |
1 | J:334078 Wang L, Park JY, Liu F, Olesen KM, Hou S, Peng JC, Infield J, Levesque AC, Wang YD, Jin H, Fan Y, Connelly PJ, Pruett-Miller SM, Hu MG, Hinds PW, Han YG, A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2206147119 |
1 | J:235720 Wang PS, Chou FS, Ramachandran S, Xia S, Chen HY, Guo F, Suraneni P, Maher BJ, Li R, Crucial roles of the Arp2/3 complex during mammalian corticogenesis. Development. 2016 Aug 1;143(15):2741-52 |
1 | J:256746 Wang X, Shan X, Gregory-Evans CY, A mouse model of aniridia reveals the in vivo downstream targets of Pax6 driving iris and ciliary body development in the eye. Biochim Biophys Acta. 2017 Jan;1863(1):60-67 |
1 | J:206929 Watson LA, Wang X, Elbert A, Kernohan KD, Galjart N, Berube NG, Dual Effect of CTCF Loss on Neuroprogenitor Differentiation and Survival. J Neurosci. 2014 Feb 19;34(8):2860-70 |
1 | J:134299 Weng J, Luo J, Cheng X, Jin C, Zhou X, Qu J, Tu L, Ai D, Li D, Wang J, Martin JF, Amendt BA, Liu M, Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6081-6 |
1 | J:242933 Whittaker DE, Riegman KL, Kasah S, Mohan C, Yu T, Sala BP, Hebaishi H, Caruso A, Marques AC, Michetti C, Smachetti ME, Shah A, Sabbioni M, Kulhanci O, Tee WW, Reinberg D, Scattoni ML, Volk H, McGonnell I, Wardle FC, Fernandes C, Basson MA, The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression. J Clin Invest. 2017 Mar 01;127(3):874-887 |
1 | J:227426 Wiegreffe C, Simon R, Peschkes K, Kling C, Strehle M, Cheng J, Srivatsa S, Liu P, Jenkins NA, Copeland NG, Tarabykin V, Britsch S, Bcl11a (Ctip1) Controls Migration of Cortical Projection Neurons through Regulation of Sema3c. Neuron. 2015 Jul 15;87(2):311-25 |
2 | J:325764 Xia Y, Zhang Y, Xu M, Zou X, Gao J, Ji MH, Chen G, Presenilin enhancer 2 is crucial for the transition of apical progenitors into neurons but into not basal progenitors in the developing hippocampus. Development. 2022 May 15;149(10):dev200272 |
1 | J:280461 Xiao D, Jin K, Xiang M, Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development. Front Mol Neurosci. 2018;11:271 |
1 | J:273281 Xu D, Yao M, Wang Y, Yuan L, Hoeck JD, Yu J, Liu L, Yeap YYC, Zhang W, Zhang F, Feng Y, Ma T, Wang Y, Ng DCH, Niu X, Su B, Behrens A, Xu Z, MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis. PLoS Biol. 2018 Dec;16(12):e2006613 |
1 | J:285763 Xu M, Han X, Liu R, Li Y, Qi C, Yang Z, Zhao C, Gao J, PDK1 Deficit Impairs the Development of the Dentate Gyrus in Mice. Cereb Cortex. 2019 Mar 1;29(3):1185-1198 |
1 | J:270427 Yabut OR, Fernandez G, Huynh T, Yoon K, Pleasure SJ, Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis. Cell Rep. 2015 Sep 29;12(12):2021-34 |
1 | J:282462 Yabut OR, Ng HX, Fernandez G, Yoon K, Kuhn J, Pleasure SJ, Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors. J Dev Biol. 2016 Dec;4(4) |
2 | J:345074 Yamanaka T, Kurosawa M, Yoshida A, Shimogori T, Hiyama A, Maity SN, Hattori N, Matsui H, Nukina N, The transcription factor NF-YA is crucial for neural progenitor maintenance during brain development. J Biol Chem. 2024 Jan 8;300(2):105629 |
1 | J:339368 Yao F, Huang S, Liu J, Tan C, Xu M, Wang D, Huang M, Zhu Y, Huang X, He S, Deletion of ARGLU1 causes global defects in alternative splicing in vivo and mouse cortical malformations primarily via apoptosis. Cell Death Dis. 2023 Aug 23;14(8):543 |
1 | J:243989 Yeung J, Goldowitz D, Wls expression in the rhombic lip orchestrates the embryonic development of the mouse cerebellum. Neuroscience. 2017 Jun 23;354:30-42 |
1 | J:363160 Yuizumi N, Harada Y, Kuniya T, Sunabori T, Koike M, Wakabayashi M, Ishihama Y, Suzuki Y, Kawaguchi D, Gotoh Y, Maintenance of neural stem-progenitor cells by the lysosomal biosynthesis regulators TFEB and TFE3 in the embryonic mouse telencephalon. Stem Cells. 2021 Jul;39(7):929-944 |
1 | J:271541 Yung AR, Druckenbrod NR, Cloutier JF, Wu Z, Tessier-Lavigne M, Goodrich LV, Netrin-1 Confines Rhombic Lip-Derived Neurons to the CNS. Cell Rep. 2018 Feb 13;22(7):1666-1680 |
1 | J:341689 Zhang B, Zhao C, Shen W, Li W, Zheng Y, Kong X, Wang J, Wu X, Zeng T, Liu Y, Zhou Y, KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors. Nat Commun. 2023 Oct 14;14(1):6489 |
1 | J:334113 Zhang F, Yoon K, Zhang DY, Kim NS, Ming GL, Song H, Epitranscriptomic regulation of cortical neurogenesis via Mettl8-dependent mitochondrial tRNA m(3)C modification. Cell Stem Cell. 2023 Mar 2;30(3):300-311.e11 |
1 | J:242341 Zhang J, Upadhya D, Lu L, Reneker LW, Fibroblast growth factor receptor 2 (FGFR2) is required for corneal epithelial cell proliferation and differentiation during embryonic development. PLoS One. 2015;10(1):e0117089 |
1 | J:238610 Zhang P, Ha T, Larouche M, Swanson D, Goldowitz D, Kruppel-Like Factor 4 Regulates Granule Cell Pax6 Expression and Cell Proliferation in Early Cerebellar Development. PLoS One. 2015;10(7):e0134390 |
1 | J:328995 Zhang SF, Dai SK, Du HZ, Wang H, Li XG, Tang Y, Liu CM, The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis. Stem Cell Reports. 2022 Sep 13;17(9):2064-2080 |
1* | J:136711 Zhao H, Yang T, Madakashira BP, Thiels CA, Bechtle CA, Garcia CM, Zhang H, Yu K, Ornitz DM, Beebe DC, Robinson ML, Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. Dev Biol. 2008 Jun 15;318(2):276-88 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
1* | J:356303 Zhao Y, Zheng D, Cvekl A, A comprehensive spatial-temporal transcriptomic analysis of differentiating nascent mouse lens epithelial and fiber cells. Exp Eye Res. 2018 Oct;175:56-72 |
1 | J:324298 Zhou J, Liu G, Zhang X, Wu C, Ma M, Wu J, Hou L, Yin B, Qiang B, Shu P, Peng X, Comparison of the Spatiotemporal Expression Patterns of Three Cre Lines, Emx1IRES-Cre, D6-Cre and hGFAP-Cre, Commonly Used in Neocortical Development Research. Cereb Cortex. 2022 Apr 5;32(8):1668-1681 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
2 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
1 | J:217063 Zou M, Luo H, Xiang M, Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord. Dev Dyn. 2015 Jan;244(1):86-97 |
Pax7 paired box 7 (Synonyms: Pax-7) | |
Results | Reference |
2 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1 | J:223814 Aujla PK, Bogdanovic V, Naratadam GT, Raetzman LT, Persistent expression of activated notch in the developing hypothalamus affects survival of pituitary progenitors and alters pituitary structure. Dev Dyn. 2015 Aug;244(8):921-34 |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1 | J:309359 Brinkmeier ML, Bando H, Camarano AC, Fujio S, Yoshimoto K, de Souza FS, Camper SA, Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. J Clin Invest. 2020 Aug 3;130(8):4501-4515 |
1 | J:188254 Budry L, Balsalobre A, Gauthier Y, Khetchoumian K, L'honore A, Vallette S, Brue T, Figarella-Branger D, Meij B, Drouin J, The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling. Genes Dev. 2012 Oct 15;26(20):2299-310 |
1 | J:264143 Cheung L, Le Tissier P, Goldsmith SG, Treier M, Lovell-Badge R, Rizzoti K, NOTCH activity differentially affects alternative cell fate acquisition and maintenance. Elife. 2018 Mar 26;7:e33318 |
1 | J:176609 Goldberg LB, Aujla PK, Raetzman LT, Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis. Dev Biol. 2011 Oct 1;358(1):23-32 |
1 | J:186396 Gruenbaum-Cohen Y, Harel I, Umansky KB, Tzahor E, Snapper SB, Shilo BZ, Schejter ED, The actin regulator N-WASp is required for muscle-cell fusion in mice. Proc Natl Acad Sci U S A. 2012 Jul 10;109(28):11211-6 |
1 | J:150129 Harel I, Nathan E, Tirosh-Finkel L, Zigdon H, Guimaraes-Camboa N, Evans SM, Tzahor E, Distinct origins and genetic programs of head muscle satellite cells. Dev Cell. 2009 Jun;16(6):822-32 |
1 | J:267950 Holzman MA, Bergmann JM, Feldman M, Landry-Truchon K, Jeannotte L, Mansfield JH, HOXA5 protein expression and genetic fate mapping show lineage restriction in the developing musculoskeletal system. Int J Dev Biol. 2018;62(11-12):785-796 |
1 | J:278542 Jia Z, Nie Y, Yue F, Kong Y, Gu L, Gavin TP, Liu X, Kuang S, A requirement of Polo-like kinase 1 in murine embryonic myogenesis and adult muscle regeneration. Elife. 2019 Aug 8;8:e47097 |
1* | J:11250 Jostes B, Walther C, Gruss P, The murine paired box gene, Pax7, is expressed specifically during the development of the nervous and muscular system. Mech Dev. 1990 Dec;33(1):27-37 |
1* | J:98918 Kassar-Duchossoy L, Giacone E, Gayraud-Morel B, Jory A, Gomes D, Tajbakhsh S, Pax3/Pax7 mark a novel population of primitive myogenic cells during development. Genes Dev. 2005 Jun 15;19(12):1426-31 |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
2 | J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97 |
1 | J:242767 Nunes AM, Wuebbles RD, Sarathy A, Fontelonga TM, Deries M, Burkin DJ, Thorsteinsdottir S, Impaired fetal muscle development and JAK-STAT activation mark disease onset and progression in a mouse model for merosin-deficient congenital muscular dystrophy. Hum Mol Genet. 2017 Jun 01;26(11):2018-2033 |
1 | J:99365 Relaix F, Rocancourt D, Mansouri A, Buckingham M, A Pax3/Pax7-dependent population of skeletal muscle progenitor cells. Nature. 2005 Jun 16;435(7044):948-53 |
1 | J:297072 Wurmser M, Chaverot N, Madani R, Sakai H, Negroni E, Demignon J, Saint-Pierre B, Mouly V, Amthor H, Tapscott S, Birchmeier C, Tajbakhsh S, Le Grand F, Sotiropoulos A, Maire P, SIX1 and SIX4 homeoproteins regulate PAX7+ progenitor cell properties during fetal epaxial myogenesis. Development. 2020 Oct 9;147(19):dev185975 |
1 | J:168032 Zacharias AL, Lewandoski M, Rudnicki MA, Gage PJ, Pitx2 is an upstream activator of extraocular myogenesis and survival. Dev Biol. 2011 Jan 15;349(2):395-405 |
1 | J:223040 Zhang T, Gunther S, Looso M, Kunne C, Kruger M, Kim J, Zhou Y, Braun T, Prmt5 is a regulator of muscle stem cell expansion in adult mice. Nat Commun. 2015;6:7140 |
Pax8 paired box 8 (Synonyms: Pax-8) | |
Results | Reference |
1* | J:171072 Carre A, Rachdi L, Tron E, Richard B, Castanet M, Schlumberger M, Bidart JM, Szinnai G, Polak M, Hes1 is required for appropriate morphogenesis and differentiation during mouse thyroid gland development. PLoS One. 2011;6(2):e16752 |
1 | J:30057 Dudley AT, Lyons KM, Robertson EJ, A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev. 1995 NOV 15;9(22):2795-2807 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1 | J:153202 Gerber SD, Steinberg F, Beyeler M, Villiger PM, Trueb B, The murine Fgfrl1 receptor is essential for the development of the metanephric kidney. Dev Biol. 2009 Nov 1;335(1):106-19 |
1 | J:352715 Kang HS, Grimm SA, Liao XH, Jetten AM, GLIS3 expression in the thyroid gland in relation to TSH signaling and regulation of gene expression. Cell Mol Life Sci. 2024 Jan 28;81(1):65 |
1* | J:31258 Kozmik Z, Kurzbauer R, Dorfler P, Busslinger M, Alternative splicing of Pax-8 gene transcripts is developmentally regulated and generates isoforms with different transactivation properties. Mol Cell Biol. 1993 Oct;13(10):6024-35 |
1* | J:297658 Kulibin AY, Malolina EA, Formation of the rete testis during mouse embryonic development. Dev Dyn. 2020 Aug 27; |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1 | J:220108 Marotta P, Amendola E, Scarfo M, De Luca P, Zoppoli P, Amoresano A, De Felice M, Di Lauro R, The paired box transcription factor Pax8 is essential for function and survival of adult thyroid cells. Mol Cell Endocrinol. 2014 Oct;396(1-2):26-36 |
1 | J:326550 Mayere C, Regard V, Perea-Gomez A, Bunce C, Neirijnck Y, Djari C, Bellido-Carreras N, Sararols P, Reeves R, Greenaway S, Simon M, Siggers P, Condrea D, Kuhne F, Gantar I, Tang F, Stevant I, Batti L, Ghyselinck NB, Wilhelm D, Greenfield A, Capel B, Chaboissier MC, Nef S, Origin, specification and differentiation of a rare supporting-like lineage in the developing mouse gonad. Sci Adv. 2022 May 27;8(21):eabm0972 |
1 | J:330583 McKey J, Anbarci DN, Bunce C, Ontiveros AE, Behringer RR, Capel B, Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii. Elife. 2022 Sep 27;11:e81088 |
1 | J:120229 Narlis M, Grote D, Gaitan Y, Boualia SK, Bouchard M, Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney. J Am Soc Nephrol. 2007 Apr;18(4):1121-9 |
1* | J:72 Plachov D, Chowdhury K, Walther C, Simon D, Guenet JL, Gruss P, Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland. Development. 1990 Oct;110(2):643-51 |
1 | J:264384 Ramalingam H, Fessler AR, Das A, Valerius MT, Basta J, Robbins L, Brown AC, Oxburgh L, McMahon AP, Rauchman M, Carroll TJ, Disparate levels of beta-catenin activity determine nephron progenitor cell fate. Dev Biol. 2018 Aug 1;440(1):13-21 |
1 | J:169693 Silberschmidt D, Rodriguez-Mallon A, Mithboakar P, Cali G, Amendola E, Sanges R, Zannini M, Scarfo M, De Luca P, Nitsch L, Di Lauro R, De Felice M, In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1. BMC Dev Biol. 2011;11:9 |
Pax9 paired box 9 (Synonyms: Pax-9) | |
Results | Reference |
1* | J:94541 Jonker L, Kist R, Aw A, Wappler I, Peters H, Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium. Mech Dev. 2004 Nov;121(11):1313-22 |
1 | J:228858 Kist R, Watson M, Crosier M, Robinson M, Fuchs J, Reichelt J, Peters H, The formation of endoderm-derived taste sensory organs requires a Pax9-dependent expansion of embryonic taste bud progenitor cells. PLoS Genet. 2014 Oct;10(10):e1004709 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
2* | J:28311 Neubuser A, Koseki H, Balling R, Characterization and developmental expression of Pax9, a paired-box-containing gene related to Pax1. Dev Biol. 1995 Aug;170(2):701-16 |
1* | J:297164 Nie X, Zheng J, Cruciger M, Yang P, Mao JJ, mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev Biol. 2020 Nov 1;467(1-2):77-87 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:49857 Peters H, Neubuser A, Kratochwil K, Balling R, Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities. Genes Dev. 1998 Sep 1;12(17):2735-47 |
2 | J:217677 Snitow ME, Li S, Morley MP, Rathi K, Lu MM, Kadzik RS, Stewart KM, Morrisey EE, Ezh2 represses the basal cell lineage during lung endoderm development. Development. 2015 Jan 1;142(1):108-17 |
Pbrm1 polybromo 1 (Synonyms: 2310032M22Rik, 2610016F04Rik, BAF180, Pb1) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
1 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1* | J:359452 Pang Y, Ruan X, Liu W, Hou L, Yin B, Shu P, Peng X, MicroRNA-495 Modulates Neuronal Layer Fate Determination by Targeting Tcf4. Int J Biol Sci. 2024;20(15):6207-6221 |
1 | J:321441 Polanetzki V, Frob F, Baroti T, Schimmel M, Tamm ER, Wegner M, Role of the Pbrm1 subunit and the PBAF complex in Schwann cell development. Sci Rep. 2022 Feb 16;12(1):2651 |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
1* | J:337458 Waldhauser V, Baroti T, Frob F, Wegner M, PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12) |
Pbx1 pre B cell leukemia homeobox 1 (Synonyms: 2310056B04Rik, D230003C07Rik, Pbx-1, Pbx1a, Pbx1b) | |
Results | Reference |
1 | J:184521 Koss M, Bolze A, Brendolan A, Saggese M, Capellini TD, Bojilova E, Boisson B, Prall OW, Elliott DA, Solloway M, Lenti E, Hidaka C, Chang CP, Mahlaoui N, Harvey RP, Casanova JL, Selleri L, Congenital Asplenia in Mice and Humans with Mutations in a Pbx/Nkx2-5/p15 Module. Dev Cell. 2012 May 15;22(5):913-26 |
1 | J:330416 Li J, Xu J, Jiang H, Zhang T, Ramakrishnan A, Shen L, Xu PX, Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance. J Am Soc Nephrol. 2021 Nov;32(11):2815-2833 |
1 | J:213341 Li W, Lin CY, Shang C, Han P, Xiong Y, Lin CJ, Yang J, Selleri L, Chang CP, Pbx1 activates Fgf10 in the mesenchyme of developing lungs. Genesis. 2014 May;52(5):399-407 |
1* | J:182007 Russell MK, Longoni M, Wells J, Maalouf FI, Tracy AA, Loscertales M, Ackerman KG, Pober BR, Lage K, Bult CJ, Donahoe PK, Congenital diaphragmatic hernia candidate genes derived from embryonic transcriptomes. Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2978-83 |
1* | J:66539 Schnabel CA, Selleri L, Jacobs Y, Warnke R, Cleary ML, Expression of Pbx1b during mammalian organogenesis. Mech Dev. 2001 Jan;100(1):131-5 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:63180 Toresson H, Parmar M, Campbell K, Expression of meis and pbx genes and their protein products in the developing telencephalon: implications for regional differentiation. Mech Dev. 2000 Jun;94(1-2):183-7 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Pbx2 pre B cell leukemia homeobox 2 (Synonyms: G17) | |
Results | Reference |
1 | J:91079 Selleri L, DiMartino J, van Deursen J, Brendolan A, Sanyal M, Boon E, Capellini T, Smith KS, Rhee J, Popperl H, Grosveld G, Cleary ML, The TALE homeodomain protein Pbx2 is not essential for development and long-term survival. Mol Cell Biol. 2004 Jun;24(12):5324-31 |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
1 | J:63180 Toresson H, Parmar M, Campbell K, Expression of meis and pbx genes and their protein products in the developing telencephalon: implications for regional differentiation. Mech Dev. 2000 Jun;94(1-2):183-7 |
Pbx3 pre B cell leukemia homeobox 3 | |
Results | Reference |
1* | J:111160 Di Giacomo G, Koss M, Capellini TD, Brendolan A, Popperl H, Selleri L, Spatio-temporal expression of Pbx3 during mouse organogenesis. Gene Expr Patterns. 2006 Oct;6(7):747-757 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:81763 Hebert JM, Lin M, Partanen J, Rossant J, McConnell SK, FGF signaling through FGFR1 is required for olfactory bulb morphogenesis. Development. 2003 Mar;130(6):1101-11 |
1 | J:264268 Li J, Wang C, Zhang Z, Wen Y, An L, Liang Q, Xu Z, Wei S, Li W, Guo T, Liu G, Tao G, You Y, Du H, Fu Z, He M, Chen B, Campbell K, Alvarez-Buylla A, Rubenstein JL, Yang Z, Transcription Factors Sp8 and Sp9 Coordinately Regulate Olfactory Bulb Interneuron Development. Cereb Cortex. 2018 Sep 1;28(9):3278-3294 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1 | J:63180 Toresson H, Parmar M, Campbell K, Expression of meis and pbx genes and their protein products in the developing telencephalon: implications for regional differentiation. Mech Dev. 2000 Jun;94(1-2):183-7 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Pbx4 pre B cell leukemia homeobox 4 (Synonyms: 2410015M21Rik) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Pcbp1 poly(rC) binding protein 1 (Synonyms: [a]CP-1, hnRNP E1, WBP17) | |
Results | Reference |
1 | J:243670 Espinoza-Lewis RA, Yang Q, Liu J, Huang ZP, Hu X, Chen D, Wang DZ, Poly(C)-binding protein 1 (Pcbp1) regulates skeletal muscle differentiation by modulating microRNA processing in myoblasts. J Biol Chem. 2017 Jun 09;292(23):9540-9550 |
Pcbp2 poly(rC) binding protein 2 (Synonyms: alphaCP-2, Hnrpx) | |
Results | Reference |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Pcdh1 protocadherin 1 (Synonyms: 2010005A06Rik) | |
Results | Reference |
1* | J:138799 Redies C, Heyder J, Kohoutek T, Staes K, Van Roy F, Expression of protocadherin-1 (Pcdh1) during mouse development. Dev Dyn. 2008 Sep;237(9):2496-505 |
Pcdh7 protocadherin 7 (Synonyms: BH-protocadherin) | |
Results | Reference |
3* | J:261000 Xiao H, Sun Z, Wan J, Hou S, Xiong Y, Overexpression of protocadherin 7 inhibits neuronal survival by downregulating BIRC5 in vitro. Exp Cell Res. 2018 May 1;366(1):71-80 |
Pcdh9 protocadherin 9 (Synonyms: 1500001L12Rik, A730003J17Rik, C530050I23Rik, C630029H24Rik, LOC382930) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Pcdh10 protocadherin 10 (Synonyms: 6430521D13Rik, 6430703F07Rik, mKIAA1400, Olpc, OL-pc) | |
Results | Reference |
1 | J:314124 Gao Y, Duque-Wilckens N, Aljazi MB, Wu Y, Moeser AJ, Mias GI, Robison AJ, He J, Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors. Commun Biol. 2021 Jun 18;4(1):756 |
1 | J:52412 Hirano S, Yan Q, Suzuki ST, Expression of a novel protocadherin, OL-protocadherin, in a subset of functional systems of the developing mouse brain. J Neurosci. 1999 Feb 1;19(3):995-1005 |
1 | J:338454 Marfull-Oromi P, Fleitas C, Zammou B, Rocandio D, Ballester-Lurbe B, Terrado J, Perez-Roger I, Espinet C, Egea J, Genetic ablation of the Rho GTPase Rnd3 triggers developmental defects in internal capsule and the globus pallidus formation. J Neurochem. 2021 Jul;158(2):197-216 |
1* | J:297365 Panezai SK, Luo Y, Vibulyaseck S, Sarpong GA, Nguyen-Minh VT, Nedelescu H, Hirano S, Sugihara I, Reorganization of longitudinal compartments in the laterally protruding paraflocculus of the postnatal mouse cerebellum. J Comp Neurol. 2020 Jul;528(10):1725-1741 |
1 | J:302307 Tran-Anh K, Zhang J, Nguyen-Minh VT, Fujita H, Hirata T, Sugihara I, Common Origin of the Cerebellar Dual Somatotopic Areas Revealed by Tracking Embryonic Purkinje Cell Clusters with Birthdate Tagging. eNeuro. 2020 Nov/Dec;7(6):ENEURO.0251-20.2020 |
2* | J:251975 Vibulyaseck S, Fujita H, Luo Y, Tran AK, Oh-Nishi A, Ono Y, Hirano S, Sugihara I, Spatial rearrangement of Purkinje cell subsets forms the transverse and longitudinal compartmentalization in the mouse embryonic cerebellum. J Comp Neurol. 2017 Oct 1;525(14):2971-2990 |
Pcdh12 protocadherin 12 (Synonyms: vascular endothelial cadherin-2, VE-cadherin-2) | |
Results | Reference |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
Pcdh15 protocadherin 15 (Synonyms: Gm9815, nmf19, roda, Ush1f) | |
Results | Reference |
1 | J:325092 Zhen Y, Cullen CL, Ricci R, Summers BS, Rehman S, Ahmed ZM, Foster AY, Emery B, Gasperini R, Young KM, Protocadherin 15 suppresses oligodendrocyte progenitor cell proliferation and promotes motility through distinct signalling pathways. Commun Biol. 2022 May 30;5(1):511 |
Pcdh17 protocadherin 17 (Synonyms: C030033F14Rik, LOC219228) | |
Results | Reference |
1 | J:330742 Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM, In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022 Oct 17;132(20):e156955 |
1 | J:135991 Lefevre G, Michel V, Weil D, Lepelletier L, Bizard E, Wolfrum U, Hardelin JP, Petit C, A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth. Development. 2008 Apr;135(8):1427-37 |
Pcdh19 protocadherin 19 (Synonyms: B530002L05Rik, LOC279653, mKIAA1313) | |
Results | Reference |
1 | J:303388 Fujitani M, Zhang S, Fujiki R, Fujihara Y, Yamashita T, A chromosome 16p13.11 microduplication causes hyperactivity through dysregulation of miR-484/protocadherin-19 signaling. Mol Psychiatry. 2017 Mar;22(3):364-374 |
1 | J:331265 Pancho A, Mitsogiannis MD, Aerts T, Dalla Vecchia M, Ebert LK, Geenen L, Noterdaeme L, Vanlaer R, Stulens A, Hulpiau P, Staes K, Van Roy F, Dedecker P, Schermer B, Seuntjens E, Modifying PCDH19 levels affects cortical interneuron migration. Front Neurosci. 2022;16:887478 |
Pcdh20 protocadherin 20 (Synonyms: C630015B17Rik, PCDH13) | |
Results | Reference |
1* | J:147117 Cheng TW, Gong Q, Secreted TARSH regulates olfactory mitral cell dendritic complexity. Eur J Neurosci. 2009 Mar;29(6):1083-95 |
Pcdha protocadherin alpha cluster (Synonyms: PCDHA@) | |
Results | Reference |
1 | J:136920 Hasegawa S, Hamada S, Kumode Y, Esumi S, Katori S, Fukuda E, Uchiyama Y, Hirabayashi T, Mombaerts P, Yagi T, The protocadherin-alpha family is involved in axonal coalescence of olfactory sensory neurons into glomeruli of the olfactory bulb in mouse. Mol Cell Neurosci. 2008 May;38(1):66-79 |
1 | J:259627 Hasegawa S, Hirabayashi T, Kondo T, Inoue K, Esumi S, Okayama A, Hamada S, Yagi T, Constitutively expressed Protocadherin-alpha regulates the coalescence and elimination of homotypic olfactory axons through its cytoplasmic region. Front Mol Neurosci. 2012;5:97 |
Pcdha4 protocadherin alpha 4 (Synonyms: Cnr1, Crnr1) | |
Results | Reference |
1 | J:96852 Morishita H, Kawaguchi M, Murata Y, Seiwa C, Hamada S, Asou H, Yagi T, Myelination triggers local loss of axonal CNR/protocadherin alpha family protein expression. Eur J Neurosci. 2004 Dec;20(11):2843-7 |
Pcdhb4 protocadherin beta 4 (Synonyms: Pcdhb5A, PcdhbD) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Pcgf2 polycomb group ring finger 2 (Synonyms: mel-18, Mel18, Rnf110, Zfp144) | |
Results | Reference |
1* | J:38105 Alkema MJ, Bronk M, Verhoeven E, Otte A, van't Veer LJ, Berns A, van Lohuizen M, Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian polycomb complex. Genes Dev. 1997 Jan 15;11(2):226-40 |
Pck1 phosphoenolpyruvate carboxykinase 1, cytosolic (Synonyms: Pck-1, PEPCK) | |
Results | Reference |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
Pcna proliferating cell nuclear antigen | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
1 | J:79879 Akiyama H, Chaboissier MC, Martin JF, Schedl A, De Crombrugghe B, The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6. Genes Dev. 2002 Nov 1;16(21):2813-28 |
1 | J:90567 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 2004 May 1;18(9):1072-87 |
1 | J:346119 Amano K, Okuzaki D, Kitaoka Y, Kato S, Fujiwara M, Tanaka S, Iida S, Pth1r in Neural Crest Cells Regulates Nasal Cartilage Differentiation. J Dent Res. 2024 Mar;103(3):308-317 |
1* | J:88220 Amasaki H, Ogawa M, Nagasao J, Mutoh K, Ichihara N, Asari M, Shiota K, Distributional changes of BrdU, PCNA, E2F1 and PAL31 molecules in developing murine palatal rugae. Ann Anat. 2003 Dec;185(6):517-23 |
1* | J:66790 Anderson SA, Marin O, Horn C, Jennings K, Rubenstein JL, Distinct cortical migrations from the medial and lateral ganglionic eminences. Development. 2001 Feb;128(3):353-63 |
1 | J:67299 Arikawa-Hirasawa E, Watanabe H, Takami H, Hassell JR, Yamada Y, Perlecan is essential for cartilage and cephalic development. Nat Genet. 1999 Nov;23(3):354-8 |
1* | J:132131 Barton KM, Levine EM, Expression patterns and cell cycle profiles of PCNA, MCM6, cyclin D1, cyclin A2, cyclin B1, and phosphorylated histone H3 in the developing mouse retina. Dev Dyn. 2008 Mar;237(3):672-82 |
1 | J:196913 Bertrand J, Stange R, Hidding H, Echtermeyer F, Nalesso G, Godmann L, Timmen M, Bruckner P, Dell'Accio F, Raschke MJ, Pap T, Dreier R, Syndecan 4 supports bone fracture repair, but not fetal skeletal development, in mice. Arthritis Rheum. 2013 Mar;65(3):743-52 |
1 | J:138769 Caubit X, Lye CM, Martin E, Core N, Long DA, Vola C, Jenkins D, Garratt AN, Skaer H, Woolf AS, Fasano L, Teashirt 3 is necessary for ureteral smooth muscle differentiation downstream of SHH and BMP4. Development. 2008 Oct;135(19):3301-10 |
1* | J:316653 Chen Z, Li W, Wang H, Wan C, Luo D, Deng S, Chen H, Chen S, Klf10 regulates odontoblast differentiation and mineralization via promoting expression of dentin matrix protein 1 and dentin sialophosphoprotein genes. Cell Tissue Res. 2016 Feb;363(2):385-98 |
1 | J:185430 Choi SW, Jeong DU, Kim JA, Lee B, Joeng KS, Long F, Kim DW, Indian Hedgehog signalling triggers Nkx3.2 protein degradation during chondrocyte maturation. Biochem J. 2012 May 1;443(3):789-98 |
2 | J:102162 Cicero S, Herrup K, Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci. 2005 Oct 19;25(42):9658-68 |
1* | J:326932 Dai SK, Liu PP, Li X, Jiao LF, Teng ZQ, Liu CM, Dynamic profiling and functional interpretation of histone lysine crotonylation and lactylation during neural development. Development. 2022 Jul 15;149(14):dev200049 |
1* | J:84942 Daniel R, Daniels E, He Z, Bateman A, Progranulin (acrogranin/PC cell-derived growth factor/granulin-epithelin precursor) is expressed in the placenta, epidermis, microvasculature, and brain during murine development. Dev Dyn. 2003 Aug;227(4):593-9 |
1* | J:121517 Danielian PS, Bender Kim CF, Caron AM, Vasile E, Bronson RT, Lees JA, E2f4 is required for normal development of the airway epithelium. Dev Biol. 2007 May 15;305(2):564-76 |
1 | J:155846 de Lange FJ, Moorman AF, Anderson RH, Manner J, Soufan AT, de Gier-de Vries C, Schneider MD, Webb S, van den Hoff MJ, Christoffels VM, Lineage and morphogenetic analysis of the cardiac valves. Circ Res. 2004 Sep 17;95(6):645-54 |
1 | J:112207 Englund C, Kowalczyk T, Daza RA, Dagan A, Lau C, Rose MF, Hevner RF, Unipolar brush cells of the cerebellum are produced in the rhombic lip and migrate through developing white matter. J Neurosci. 2006 Sep 6;26(36):9184-95 |
1 | J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489 |
1 | J:144651 Farkas LM, Haffner C, Giger T, Khaitovich P, Nowick K, Birchmeier C, Paabo S, Huttner WB, Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex. Neuron. 2008 Oct 9;60(1):40-55 |
1 | J:292306 Francis R, Guo H, Streutker C, Ahmed M, Yung T, Dirks PB, He HH, Kim TH, Gastrointestinal transcription factors drive lineage-specific developmental programs in organ specification and cancer. Sci Adv. 2019 Dec;5(12):eaax8898 |
1* | J:294694 Furusawa T, Lim JH, Catez F, Birger Y, Mackem S, Bustin M, Down-regulation of nucleosomal binding protein HMGN1 expression during embryogenesis modulates Sox9 expression in chondrocytes. Mol Cell Biol. 2006 Jan;26(2):592-604 |
1 | J:233661 Garcia-Calero E, Botella-Lopez A, Bahamonde O, Perez-Balaguer A, Martinez S, FoxP2 protein levels regulate cell morphology changes and migration patterns in the vertebrate developing telencephalon. Brain Struct Funct. 2016 Jul;221(6):2905-17 |
1 | J:356109 Ge W, Tan SJ, Wang SH, Li L, Sun XF, Shen W, Wang X, Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development. Theranostics. 2020;10(17):7581-7598 |
2 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:196581 Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G, The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-beta signaling. Dev Biol. 2013 May 15;377(2):415-27 |
1 | J:342170 Gura MA, Bartholomew MA, Abt KM, Relovska S, Seymour KA, Freiman RN, Transcription and chromatin regulation by TAF4b during cellular quiescence of developing prospermatogonia. Front Cell Dev Biol. 2023;11:1270408 |
1 | J:185218 Hall-Glenn F, De Young RA, Huang BL, van Handel B, Hofmann JJ, Chen TT, Choi A, Ong JR, Benya PD, Mikkola H, Iruela-Arispe ML, Lyons KM, CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PLoS One. 2012;7(2):e30562 |
1 | J:135676 Heath E, Tahri D, Andermarcher E, Schofield P, Fleming S, Boulter CA, Abnormal skeletal and cardiac development, cardiomyopathy, muscle atrophy and cataracts in mice with a targeted disruption of the Nov (Ccn3) gene. BMC Dev Biol. 2008;8:18 |
1 | J:196059 Hodge RD, Garcia AJ 3rd, Elsen GE, Nelson BR, Mussar KE, Reiner SL, Ramirez JM, Hevner RF, Tbr2 expression in Cajal-Retzius cells and intermediate neuronal progenitors is required for morphogenesis of the dentate gyrus. J Neurosci. 2013 Feb 27;33(9):4165-80 |
1 | J:121230 Hoogaars WM, Engel A, Brons JF, Verkerk AO, de Lange FJ, Wong LY, Bakker ML, Clout DE, Wakker V, Barnett P, Ravesloot JH, Moorman AF, Verheijck EE, Christoffels VM, Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria. Genes Dev. 2007 May 1;21(9):1098-112 |
1 | J:191801 Huang CC, Shih MC, Hsu NC, Chien Y, Chung BC, Fetal glucocorticoid synthesis is required for development of fetal adrenal medulla and hypothalamus feedback suppression. Endocrinology. 2012 Oct;153(10):4749-56 |
1* | J:283394 Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S, Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162 |
1 | J:83260 Ivkovic S, Yoon BS, Popoff SN, Safadi FF, Libuda DE, Stephenson RC, Daluiski A, Lyons KM, Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development. Development. 2003 Jun;130(12):2779-91 |
1 | J:135131 Kashiwagi M, Morgan BA, Georgopoulos K, The chromatin remodeler Mi-2beta is required for establishment of the basal epidermis and normal differentiation of its progeny. Development. 2007 Apr;134(8):1571-82 |
1 | J:193195 Katoh K, Yamazaki R, Onishi A, Sanuki R, Furukawa T, G9a histone methyltransferase activity in retinal progenitors is essential for proper differentiation and survival of mouse retinal cells. J Neurosci. 2012 Dec 5;32(49):17658-70 |
1 | J:155442 Kawaki H, Kubota S, Suzuki A, Lazar N, Yamada T, Matsumura T, Ohgawara T, Maeda T, Perbal B, Lyons KM, Takigawa M, Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage. J Bone Miner Res. 2008 Nov;23(11):1751-64 |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1 | J:168981 Kim JJ, Gill PS, Rotin L, van Eede M, Henkelman RM, Hui CC, Rosenblum ND, Suppressor of Fused Controls Mid-Hindbrain Patterning and Cerebellar Morphogenesis via GLI3 Repressor. J Neurosci. 2011 Feb 2;31(5):1825-36 |
1 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
1 | J:201110 Komada M, Iguchi T, Takeda T, Ishibashi M, Sato M, Smoothened controls cyclin D2 expression and regulates the generation of intermediate progenitors in the developing cortex. Neurosci Lett. 2013 Jun 28;547:87-91 |
1* | J:231259 Krill KT, Gurdziel K, Heaton JH, Simon DP, Hammer GD, Dicer deficiency reveals microRNAs predicted to control gene expression in the developing adrenal cortex. Mol Endocrinol. 2013 May;27(5):754-68 |
1 | J:195630 Krolewski RC, Packard A, Jang W, Wildner H, Schwob JE, Ascl1 (Mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium. PLoS One. 2012;7(12):e51737 |
1* | J:143513 Lathia JD, Okun E, Tang SC, Griffioen K, Cheng A, Mughal MR, Laryea G, Selvaraj PK, ffrench-Constant C, Magnus T, Arumugam TV, Mattson MP, Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation. J Neurosci. 2008 Dec 17;28(51):13978-84 |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
1 | J:191367 Lee Y, Katyal S, Downing SM, Zhao J, Russell HR, McKinnon PJ, Neurogenesis requires TopBP1 to prevent catastrophic replicative DNA damage in early progenitors. Nat Neurosci. 2012 Jun;15(6):819-26 |
1 | J:181920 Lee Y, Shull ER, Frappart PO, Katyal S, Enriquez-Rios V, Zhao J, Russell HR, Brown EJ, McKinnon PJ, ATR maintains select progenitors during nervous system development. EMBO J. 2012 Mar 7;31(5):1177-89 |
1* | J:205247 Li CC, Chu HY, Yang CW, Chou CK, Tsai TF, Aurora-A overexpression in mouse liver causes p53-dependent premitotic arrest during liver regeneration. Mol Cancer Res. 2009 May;7(5):678-88 |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1 | J:193853 Makino Y, Takahashi Y, Tanabe R, Tamamura Y, Watanabe T, Haraikawa M, Hamagaki M, Hata K, Kanno J, Yoneda T, Saga Y, Goseki-Sone M, Kaneko K, Yamaguchi A, Iimura T, Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone. 2013 Mar;53(1):248-58 |
1 | J:302193 McDonough A, Elsen GE, Daza RM, Bachleda AR, Pizzo D, DelleTorri OM, Hevner RF, Unipolar (Dendritic) Brush Cells Are Morphologically Complex and Require Tbr2 for Differentiation and Migration. Front Neurosci. 2020;14:598548 |
1 | J:198698 Meng L, Lin T, Peng G, Hsu JK, Lee S, Lin SY, Tsai RY, Nucleostemin deletion reveals an essential mechanism that maintains the genomic stability of stem and progenitor cells. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11415-20 |
1 | J:88344 Miao D, Liu H, Plut P, Niu M, Huo R, Goltzman D, Henderson JE, Impaired endochondral bone development and osteopenia in Gli2-deficient mice. Exp Cell Res. 2004 Mar 10;294(1):210-22 |
1 | J:53721 Muglia LJ, Bae DS, Brown TT, Vogt SK, Alvarez JG, Sunday ME, Majzoub JA, Proliferation and differentiation defects during lung development in corticotropin-releasing hormone-deficient mice. Am J Respir Cell Mol Biol. 1999 Feb;20(2):181-8 |
1 | J:143162 Murata J, Tokunaga A, Okano H, Kubo T, Mapping of notch activation during cochlear development in mice: implications for determination of prosensory domain and cell fate diversification. J Comp Neurol. 2006 Jul 20;497(3):502-18 |
1* | J:132157 Nakamura T, de Vega S, Fukumoto S, Jimenez L, Unda F, Yamada Y, Transcription factor epiprofin is essential for tooth morphogenesis by regulating epithelial cell fate and tooth number. J Biol Chem. 2008 Feb 22;283(8):4825-33 |
1* | J:136997 Ohtaka-Maruyama C, Miwa A, Kawano H, Kasai M, Okado H, Spatial and temporal expression of RP58, a novel zinc finger transcriptional repressor, in mouse brain. J Comp Neurol. 2007 Jun 20;502(6):1098-108 |
1 | J:150768 Okado H, Ohtaka-Maruyama C, Sugitani Y, Fukuda Y, Ishida R, Hirai S, Miwa A, Takahashi A, Aoki K, Mochida K, Suzuki O, Honda T, Nakajima K, Ogawa M, Terashima T, Matsuda J, Kawano H, Kasai M, The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Dev Biol. 2009 Jul 15;331(2):140-51 |
1 | J:206963 Orieux G, Picault L, Slembrouck A, Roger JE, Guillonneau X, Sahel JA, Saule S, McPherson JP, Goureau O, Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells. J Neurosci. 2014 Jan 22;34(4):1530-41 |
1 | J:246653 Park JC, Jeong WJ, Kim MY, Min D, Choi KY, Retinoic-acid-mediated HRas stabilization induces neuronal differentiation of neural stem cells during brain development. J Cell Sci. 2016 Aug 01;129(15):2997-3007 |
1 | J:309481 Park NR, Lim KE, Han MS, Che X, Park CY, Kim JE, Taniuchi I, Bae SC, Choi JY, Core Binding Factor beta Plays a Critical Role During Chondrocyte Differentiation. J Cell Physiol. 2016 Jan;231(1):162-71 |
1 | J:309456 Pearson HB, McGlinn E, Phesse TJ, Schluter H, Srikumar A, Godde NJ, Woelwer CB, Ryan A, Phillips WA, Ernst M, Kaur P, Humbert P, The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis. Mol Cancer. 2015 Sep 17;14:169 |
1 | J:294004 Piprek RP, Kolasa M, Podkowa D, Kloc M, Kubiak JZ, N-Cadherin Is Critical for the Survival of Germ Cells, the Formation of Steroidogenic Cells, and the Architecture of Developing Mouse Gonads. Cells. 2019 Dec 11;8(12):1610 |
1* | J:325976 Piprek RP, Rams-Pociecha I, Zdanowski R, Kloc M, Kubiak JZ, Desmoplakin (Dsp) conditional knockout in NR5A1+ somatic cells affects germ cell survival in developing mouse gonads. Reproduction. 2022 Feb 24;163(4):199-207 |
1 | J:73971 Ponnio T, Burton Q, Pereira FA, Wu DK, Conneely OM, The nuclear receptor Nor-1 is essential for proliferation of the semicircular canals of the mouse inner ear. Mol Cell Biol. 2002 Feb;22(3):935-45 |
1 | J:105554 Porse BT, Pedersen TA, Hasemann MS, Schuster MB, Kirstetter P, Luedde T, Damgaard I, Kurz E, Schjerling CK, Nerlov C, The proline-histidine-rich CDK2/CDK4 interaction region of C/EBPalpha is dispensable for C/EBPalpha-mediated growth regulation in vivo. Mol Cell Biol. 2006 Feb;26(3):1028-37 |
1 | J:79935 Sakai Y, Suetake I, Itoh K, Mizugaki M, Tajima S, Yamashina S, Expression of DNA methyltransferase (Dnmt1) in testicular germ cells during development of mouse embryo. Cell Struct Funct. 2001 Dec;26(6):685-91 |
1 | J:195711 Shi F, Fan Y, Zhang L, Meng L, Zhi H, Hu H, Lin A, The expression of Pax6 variants is subject to posttranscriptional regulation in the developing mouse eyelid. PLoS One. 2013;8(1):e53919 |
1* | J:80666 Smits P, Li P, Mandel J, Zhang Z, Deng JM, Behringer RR, de Croumbrugghe B, Lefebvre V, The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001 Aug;1(2):277-90 |
1 | J:298594 Stepien BK, Naumann R, Holtz A, Helppi J, Huttner WB, Vaid S, Lengthening Neurogenic Period during Neocortical Development Causes a Hallmark of Neocortex Expansion. Curr Biol. 2020 Nov 2;30(21):4227-4237.e5 |
1 | J:159839 Stevens HE, Smith KM, Maragnoli ME, Fagel D, Borok E, Shanabrough M, Horvath TL, Vaccarino FM, Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits. J Neurosci. 2010 Apr 21;30(16):5590-602 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1 | J:186876 Sugiyama N, Tsukiyama T, Yamaguchi TP, Yokoyama T, The canonical Wnt signaling pathway is not involved in renal cyst development in the kidneys of inv mutant mice. Kidney Int. 2011 May;79(9):957-65 |
1* | J:203065 Sugiyama T, Osumi N, Katsuyama Y, The germinal matrices in the developing dentate gyrus are composed of neuronal progenitors at distinct differentiation stages. Dev Dyn. 2013 Dec;242(12):1442-53 |
1 | J:306384 Terrey M, Adamson SI, Chuang JH, Ackerman SL, Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology. Elife. 2021 Apr 26;10:e66904 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
1* | J:142315 Tsai CY, Chou CK, Yang CW, Lai YC, Liang CC, Chen CM, Tsai TF, Hurp deficiency in mice leads to female infertility caused by an implantation defect. J Biol Chem. 2008 Sep 26;283(39):26302-6 |
1 | J:80512 Tsai RY, McKay RD, A nucleolar mechanism controlling cell proliferation in stem cells and cancer cells. Genes Dev. 2002 Dec 1;16(23):2991-3003 |
1 | J:233479 Vong KI, Leung CK, Behringer RR, Kwan KM, Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum. Mol Brain. 2015;8:25 |
1 | J:278336 Wang W, Chun H, Baek J, Sadik JE, Shirazyan A, Razavi P, Lopez N, Lyons KM, The TGFbeta type I receptor TGFbetaRI functions as an inhibitor of BMP signaling in cartilage. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15570-15579 |
1 | J:251156 Wen Q, Wang Y, Tang J, Cheng CY, Liu YX, Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development. PLoS One. 2016;11(12):e0167920 |
1 | J:363331 Wu ML, Wheeler K, Silasi R, Lupu F, Griffin CT, Endothelial Chromatin-Remodeling Enzymes Regulate the Production of Critical ECM Components During Murine Lung Development. Arterioscler Thromb Vasc Biol. 2024 Aug;44(8):1784-1798 |
4 | J:180831 Xu B, Hua J, Zhang Y, Jiang X, Zhang H, Ma T, Zheng W, Sun R, Shen W, Sha J, Cooke HJ, Shi Q, Proliferating cell nuclear antigen (PCNA) regulates primordial follicle assembly by promoting apoptosis of oocytes in fetal and neonatal mouse ovaries. PLoS One. 2011;6(1):e16046 |
1* | J:272566 Yang R, Wang H, Kang B, Chen B, Shi Y, Yang S, Sun L, Liu Y, Xiao W, Zhang T, Yang J, Zhang Y, Zhu M, Xu P, Chang Y, Jia Y, Huang Y, CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
1* | J:136711 Zhao H, Yang T, Madakashira BP, Thiels CA, Bechtle CA, Garcia CM, Zhang H, Yu K, Ornitz DM, Beebe DC, Robinson ML, Fibroblast growth factor receptor signaling is essential for lens fiber cell differentiation. Dev Biol. 2008 Jun 15;318(2):276-88 |
1* | J:68672 Zhao J, Chen H, Peschon JJ, Shi W, Zhang Y, Frank SJ, Warburton D, Pulmonary hypoplasia in mice lacking tumor necrosis factor-alpha converting enzyme indicates an indispensable role for cell surface protein shedding during embryonic lung branching morphogenesis. Dev Biol. 2001 Apr 1;232(1):204-18 |
1* | J:157752 Zimmer C, Tiveron MC, Bodmer R, Cremer H, Dynamics of Cux2 expression suggests that an early pool of SVZ precursors is fated to become upper cortical layer neurons. Cereb Cortex. 2004 Dec;14(12):1408-20 |
Pcnt pericentrin (kendrin) (Synonyms: m239Asp, m275Asp, mKIAA0402, Pcnt2) | |
Results | Reference |
1 | J:358347 Dias AP, Rehmani T, Salih M, Tuana B, Tail-anchored membrane protein SLMAP3 is essential for targeting centrosomal proteins to the nuclear envelope in skeletal myogenesis. Open Biol. 2024 Oct;14(10):240094 |
1* | J:215665 Insolera R, Shao W, Airik R, Hildebrandt F, Shi SH, SDCCAG8 regulates pericentriolar material recruitment and neuronal migration in the developing cortex. Neuron. 2014 Aug 20;83(4):805-22 |
1 | J:292113 Lin YN, Lee YS, Li SK, Tang TK, Loss of CPAP in developing mouse brain and its functional implication for human primary microcephaly. J Cell Sci. 2020 Jun 24;133(12):jcs243592 |
1 | J:294113 Lough KJ, Byrd KM, Descovich CP, Spitzer DC, Bergman AJ, Beaudoin GM 3rd, Reichardt LF, Williams SE, Telophase correction refines division orientation in stratified epithelia. Elife. 2019 Dec 13;8:e49249 |
1 | J:317613 Patnaik SR, Kretschmer V, Brucker L, Schneider S, Volz AK, Oancea-Castillo LDR, May-Simera HL, Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation. Cell Mol Life Sci. 2019 Feb;76(4):757-775 |
1 | J:206876 Song JY, Park R, Kim JY, Hughes L, Lu L, Kim S, Johnson RL, Cho SH, Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev Biol. 2014 Feb 15;386(2):281-90 |
1 | J:338452 Wang D, Li H, Chandel NS, Dou Y, Yi R, MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters. Nat Commun. 2023 Jul 21;14(1):4404 |
1 | J:153606 Wodarczyk C, Rowe I, Chiaravalli M, Pema M, Qian F, Boletta A, A novel mouse model reveals that polycystin-1 deficiency in ependyma and choroid plexus results in dysfunctional cilia and hydrocephalus. PLoS One. 2009;4(9):e7137 |
Pcp4 Purkinje cell protein 4 (Synonyms: P16Rimb19, Pcp-4, Pep19) | |
Results | Reference |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
Pcp4l1 Purkinje cell protein 4-like 1 (Synonyms: 1500036F01Rik) | |
Results | Reference |
1* | J:89168 Bulfone A, Caccioppoli C, Pardini C, Faedo A, Martinez S, Banfi S, Pcp4l1, a novel gene encoding a Pcp4-like polypeptide, is expressed in specific domains of the developing brain. Gene Expr Patterns. 2004 May;4(3):297-301 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Pcsk1 proprotein convertase subtilisin/kexin type 1 (Synonyms: Nec-1, Nec1, PC1, PC3, Phpp-1, prohormone convertase 1/3, SPC3) | |
Results | Reference |
1* | J:191140 Grigoryan M, Kedees MH, Guz Y, Teitelman G, Phenotype of entero-endocrine L cells becomes restricted during development. Dev Dyn. 2012 Dec;241(12):1986-92 |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
Pcsk2 proprotein convertase subtilisin/kexin type 2 (Synonyms: 6330411F23Rik, Nec-2, Nec2, PC2, Phpp-2, prohormone convertase 2, SPC2) | |
Results | Reference |
1 | J:188254 Budry L, Balsalobre A, Gauthier Y, Khetchoumian K, L'honore A, Vallette S, Brue T, Figarella-Branger D, Meij B, Drouin J, The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling. Genes Dev. 2012 Oct 15;26(20):2299-310 |
1* | J:191140 Grigoryan M, Kedees MH, Guz Y, Teitelman G, Phenotype of entero-endocrine L cells becomes restricted during development. Dev Dyn. 2012 Dec;241(12):1986-92 |
1* | J:143548 Himes AD, Raetzman LT, Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1. Dev Biol. 2009 Jan 1;325(1):151-61 |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
Pcsk5 proprotein convertase subtilisin/kexin type 5 (Synonyms: b2b1549Clo, b2b585Clo, PC5/6A, PC5A, PC6, SPC6) | |
Results | Reference |
1* | J:34068 Constam DB, Calfon M, Robertson EJ, SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis. J Cell Biol. 1996 Jul;134(1):181-91 |
Pcsk6 proprotein convertase subtilisin/kexin type 6 (Synonyms: b2b2830Clo, PACE4, SPC4) | |
Results | Reference |
1* | J:34068 Constam DB, Calfon M, Robertson EJ, SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis. J Cell Biol. 1996 Jul;134(1):181-91 |
Pcsk7 proprotein convertase subtilisin/kexin type 7 (Synonyms: SPC7) | |
Results | Reference |
2 | J:34068 Constam DB, Calfon M, Robertson EJ, SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis. J Cell Biol. 1996 Jul;134(1):181-91 |
Pctp phosphatidylcholine transfer protein (Synonyms: PC-TP, StarD2) | |
Results | Reference |
1* | J:310743 Lin S, Ikegami M, Moon C, Naren AP, Shannon JM, Lysophosphatidylcholine Acyltransferase 1 (LPCAT1) Specifically Interacts with Phospholipid Transfer Protein StarD10 to Facilitate Surfactant Phospholipid Trafficking in Alveolar Type II Cells. J Biol Chem. 2015 Jul 24;290(30):18559-74 |
Pcx pyruvate carboxylase (Synonyms: Pc) | |
Results | Reference |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
Pdc phosducin (Synonyms: Pdc, Rpr-1, Rpr1) | |
Results | Reference |
1 | J:285747 Liu S, Liu X, Li S, Huang X, Qian H, Jin K, Xiang M, Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5016-5027 |
Pdcd6ip programmed cell death 6 interacting protein (Synonyms: AIP1, Alix, mKIAA1375) | |
Results | Reference |
1* | J:339600 Hermosilla Aguayo V, Martin P, Tian N, Zheng J, Aho R, Losa M, Selleri L, ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42 |
Pdcd10 programmed cell death 10 (Synonyms: 2410003B13Rik, CCM3, TF-1 cell apoptosis related protein-15, Tfa15) | |
Results | Reference |
1 | J:208651 Louvi A, Nishimura S, Gunel M, Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration. Development. 2014 Mar;141(6):1404-15 |
Pde3b phosphodiesterase 3B, cGMP-inhibited (Synonyms: 9830102A01Rik) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:281878 Yook C, Kim K, Kim D, Kang H, Kim SG, Kim E, Kim SY, A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice. Front Mol Neurosci. 2019;12:241 |
Pde10a phosphodiesterase 10A | |
Results | Reference |
1 | J:309347 Botella-Lopez A, Garcia-Lopez R, Pombero A, Martinez S, Radial glia fibers translate Fgf8 morphogenetic signals to generate a thalamic nuclear complex protomap in the mantle layer. Brain Struct Funct. 2019 Mar;224(2):661-679 |
Pdgfa platelet derived growth factor, alpha | |
Results | Reference |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:54912 Karlsson L, Bondjers C, Betsholtz C, Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle. Development. 1999 Jun;126(12):2611-21 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1 | J:62052 Li X, Ponten A, Aase K, Karlsson L, Abramsson A, Uutela M, Backstrom G, Hellstrom M, Bostrom H, Li H, Soriano P, Betsholtz C, Heldin CH, Alitalo K, Ostman A, Eriksson U, PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor [see comments]. Nat Cell Biol. 2000 May;2(5):302-9 |
1* | J:43767 Lindahl P, Karlsson L, Hellstrom M, Gebre-Medhin S, Willetts K, Heath JK, Betsholtz C, Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development. Development. 1997 Oct;124(20):3943-53 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
1 | J:171519 Reneker LW, Chen H, Overbeek PA, Activation of unfolded protein response in transgenic mouse lenses. Invest Ophthalmol Vis Sci. 2011;52(5):2100-8 |
1 | J:95139 Xu X, Bringas P Jr, Soriano P, Chai Y, PDGFR-alpha signaling is critical for tooth cusp and palate morphogenesis. Dev Dyn. 2005 Jan;232(1):75-84 |
Pdgfb platelet derived growth factor, B polypeptide (Synonyms: PDGF-B, Sis) | |
Results | Reference |
1 | J:239651 Hurtado R, Zewdu R, Mtui J, Liang C, Aho R, Kurylo C, Selleri L, Herzlinger D, Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning. Development. 2015 Aug 01;142(15):2653-64 |
1* | J:95138 Inanlou MR, Kablar B, Abnormal development of the intercostal muscles and the rib cage in Myf5-/- embryos leads to pulmonary hypoplasia. Dev Dyn. 2005 Jan;232(1):43-54 |
1 | J:50064 Lindahl P, Hellstrom M, Kalen M, Karlsson L, Pekny M, Pekna M, Soriano P, Betsholtz C, Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli. Development. 1998 Sep;125(17):3313-22 |
1 | J:41523 Lindahl P, Johansson BR, Leveen P, Betsholtz C, Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science. 1997 Jul 11;277(5323):242-5 |
1 | J:178367 Slamon DJ, Cline MJ, Expression of cellular oncogenes during embryonic and fetal development of the mouse. Proc Natl Acad Sci U S A. 1984 Nov;81(22):7141-5 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
Pdgfc platelet-derived growth factor, C polypeptide (Synonyms: 1110064L01Rik, PDGF-C) | |
Results | Reference |
1* | J:73808 Aase K, Abramsson A, Karlsson L, Betsholtz C, Eriksson U, Expression analysis of PDGF-C in adult and developing mouse tissues. Mech Dev. 2002 Jan;110(1-2):187-91 |
1* | J:327413 Gillnas S, Gallini R, He L, Betsholtz C, Andrae J, Severe cerebellar malformations in mutant mice demonstrate a role for PDGF-C/PDGFRalpha signalling in cerebellar development. Biol Open. 2022 Aug 15;11(8):bio059431 |
1 | J:62052 Li X, Ponten A, Aase K, Karlsson L, Abramsson A, Uutela M, Backstrom G, Hellstrom M, Bostrom H, Li H, Soriano P, Betsholtz C, Heldin CH, Alitalo K, Ostman A, Eriksson U, PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor [see comments]. Nat Cell Biol. 2000 May;2(5):302-9 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
Pdgfra platelet derived growth factor receptor, alpha polypeptide (Synonyms: CD140a, Pdgfr-2) | |
Results | Reference |
1* | J:130196 Alfonsi F, Filippi P, Salaun D, deLapeyriere O, Durbec P, LIFR beta plays a major role in neuronal identity determination and glial differentiation in the mouse facial nucleus. Dev Biol. 2008 Jan 1;313(1):267-78 |
1 | J:70255 Andrae J, Hansson I, Afink GB, Nister M, Platelet-derived growth factor receptor-alpha in ventricular zone cells and in developing neurons. Mol Cell Neurosci. 2001 Jun;17(6):1001-13 |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1 | J:227058 Chen D, Wang X, Liang D, Gordon J, Mittal A, Manley N, Degenhardt K, Astrof S, Fibronectin signals through integrin alpha5beta1 to regulate cardiovascular development in a cell type-specific manner. Dev Biol. 2015 Nov 15;407(2):195-210 |
1* | J:284137 Chen L, Toke NH, Luo S, Vasoya RP, Aita R, Parthasarathy A, Tsai YH, Spence JR, Verzi MP, HNF4 factors control chromatin accessibility and are redundantly required for maturation of the fetal intestine. Development. 2019 Aug 6;146(19):dev179432 |
1 | J:217413 Choe Y, Huynh T, Pleasure SJ, Migration of oligodendrocyte progenitor cells is controlled by transforming growth factor beta family proteins during corticogenesis. J Neurosci. 2014 Nov 5;34(45):14973-83 |
1 | J:227188 Choe Y, Huynh T, Pleasure SJ, Epithelial cells supply Sonic Hedgehog to the perinatal dentate gyrus via transport by platelets. Elife. 2015;4 |
1 | J:359797 Coren L, Zaffryar-Eilot S, Odeh A, Kaganovsky A, Hasson P, Fibroblast diversification is an embryonic process dependent on muscle contraction. Cell Rep. 2024 Dec 4;43(12):115034 |
1 | J:212081 Dai ZM, Sun S, Wang C, Huang H, Hu X, Zhang Z, Lu QR, Qiu M, Stage-specific regulation of oligodendrocyte development by Wnt/beta-catenin signaling. J Neurosci. 2014 Jun 18;34(25):8467-73 |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:316977 Endale M, Ahlfeld S, Bao E, Chen X, Green J, Bess Z, Weirauch MT, Xu Y, Perl AK, Temporal, spatial, and phenotypical changes of PDGFRalpha expressing fibroblasts during late lung development. Dev Biol. 2017 May 15;425(2):161-175 |
1* | J:311215 Fazilaty H, Brugger MD, Valenta T, Szczerba BM, Berkova L, Doumpas N, Hausmann G, Scharl M, Basler K, Tracing colonic embryonic transcriptional profiles and their reactivation upon intestinal damage. Cell Rep. 2021 Aug 3;36(5):109484 |
1* | J:74236 Fu H, Qi Y, Tan M, Cai J, Takebayashi H, Nakafuku M, Richardson W, Qiu M, Dual origin of spinal oligodendrocyte progenitors and evidence for the cooperative role of Olig2 and Nkx2.2 in the control of oligodendrocyte differentiation. Development. 2002 Feb;129(3):681-93 |
1 | J:171201 Furusho M, Kaga Y, Ishii A, Hebert JM, Bansal R, Fibroblast growth factor signaling is required for the generation of oligodendrocyte progenitors from the embryonic forebrain. J Neurosci. 2011 Mar 30;31(13):5055-66 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1* | J:86790 Gitler AD, Lu MM, Jiang YQ, Epstein JA, Gruber PJ, Molecular markers of cardiac endocardial cushion development. Dev Dyn. 2003 Dec;228(4):643-50 |
1 | J:283354 Guiu J, Hannezo E, Yui S, Demharter S, Ulyanchenko S, Maimets M, Jorgensen A, Perlman S, Lundvall L, Mamsen LS, Larsen A, Olesen RH, Andersen CY, Thuesen LL, Hare KJ, Pers TH, Khodosevich K, Simons BD, Jensen KB, Tracing the origin of adult intestinal stem cells. Nature. 2019 Jun;570(7759):107-111 |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
1 | J:293063 Hamashima T, Ishii Y, Nguyen LQ, Okuno N, Sang Y, Matsushima T, Kurashige Y, Takebayashi H, Mori H, Fujimori T, Yamamoto S, Sasahara M, Oligodendrogenesis and Myelin Formation in the Forebrain Require Platelet-derived Growth Factor Receptor-alpha. Neuroscience. 2020 Jun 1;436:11-26 |
1* | J:83560 Hamilton TG, Klinghoffer RA, Corrin PD, Soriano P, Evolutionary divergence of platelet-derived growth factor alpha receptor signaling mechanisms. Mol Cell Biol. 2003 Jun;23(11):4013-25 |
1* | J:231833 Hashimoto R, Hori K, Owa T, Miyashita S, Dewa K, Masuyama N, Sakai K, Hayase Y, Seto Y, Inoue YU, Inoue T, Ichinohe N, Kawaguchi Y, Akiyama H, Koizumi S, Hoshino M, Origins of oligodendrocytes in the cerebellum, whose development is controlled by the transcription factor, Sox9. Mech Dev. 2016 May;140:25-40 |
1 | J:267950 Holzman MA, Bergmann JM, Feldman M, Landry-Truchon K, Jeannotte L, Mansfield JH, HOXA5 protein expression and genetic fate mapping show lineage restriction in the developing musculoskeletal system. Int J Dev Biol. 2018;62(11-12):785-796 |
1* | J:314181 Holzman MA, Ryckman A, Finkelstein TM, Landry-Truchon K, Schindler KA, Bergmann JM, Jeannotte L, Mansfield JH, HOXA5 Participates in Brown Adipose Tissue and Epaxial Skeletal Muscle Patterning and in Brown Adipocyte Differentiation. Front Cell Dev Biol. 2021;9:632303 |
1 | J:162581 Huillard E, Ziercher L, Blond O, Wong M, Deloulme JC, Souchelnytskyi S, Baudier J, Cochet C, Buchou T, Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalon. Mol Cell Biol. 2010 Jun;30(11):2737-49 |
1 | J:349163 Huycke TR, Hakkinen TJ, Miyazaki H, Srivastava V, Barruet E, McGinnis CS, Kalantari A, Cornwall-Scoones J, Vaka D, Zhu Q, Jo H, Oria R, Weaver VM, DeGrado WF, Thomson M, Garikipati K, Boffelli D, Klein OD, Gartner ZJ, Patterning and folding of intestinal villi by active mesenchymal dewetting. Cell. 2024 Jun 6;187(12):3072-3089.e20 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:54912 Karlsson L, Bondjers C, Betsholtz C, Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle. Development. 1999 Jun;126(12):2611-21 |
1* | J:347773 Kim HY, Kang B, Lee PR, Kim K, Hong GS, Expression patterns of Piezo1 in the developing mouse forebrain. Brain Struct Funct. 2024 Apr;229(3):759-773 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1 | J:240472 Kumar N, Srivillibhuthur M, Joshi S, Walton KD, Zhou A, Faller WJ, Perekatt AO, Sansom OJ, Gumucio DL, Xing J, Bonder EM, Gao N, White E, Verzi MP, A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis. Development. 2016 Oct 15;143(20):3711-3722 |
1 | J:325446 Lepiemme F, Stoufflet J, Javier-Torrent M, Mazzucchelli G, Silva CG, Nguyen L, Oligodendrocyte precursors guide interneuron migration by unidirectional contact repulsion. Science. 2022 May 20;376(6595):eabn6204 |
1 | J:250062 Li A, Ma S, Smith SM, Lee MK, Fischer A, Borok Z, Bellusci S, Li C, Minoo P, Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate. BMC Biol. 2016 Mar 16;14:19 |
1 | J:361546 Li J, Yang F, Tian Y, Wang Z, Qi D, Yang Z, Song J, Ding J, Wang X, Zhang Z, Lateral/caudal ganglionic eminence makes limited contribution to cortical oligodendrocytes. Elife. 2024 Sep 11;13 |
1 | J:205567 Li K, Leung AW, Guo Q, Yang W, Li JY, Shp2-Dependent ERK Signaling Is Essential for Induction of Bergmann Glia and Foliation of the Cerebellum. J Neurosci. 2014 Jan 15;34(3):922-31 |
1 | J:62052 Li X, Ponten A, Aase K, Karlsson L, Abramsson A, Uutela M, Backstrom G, Hellstrom M, Bostrom H, Li H, Soriano P, Betsholtz C, Heldin CH, Alitalo K, Ostman A, Eriksson U, PDGF-C is a new protease-activated ligand for the PDGF alpha-receptor [see comments]. Nat Cell Biol. 2000 May;2(5):302-9 |
1 | J:214993 Lin C, Chen MH, Yao E, Song H, Gacayan R, Hui CC, Chuang PT, Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development. Dev Biol. 2014 Aug 15;392(2):324-33 |
1 | J:41523 Lindahl P, Johansson BR, Leveen P, Betsholtz C, Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science. 1997 Jul 11;277(5323):242-5 |
1* | J:43767 Lindahl P, Karlsson L, Hellstrom M, Gebre-Medhin S, Willetts K, Heath JK, Betsholtz C, Alveogenesis failure in PDGF-A-deficient mice is coupled to lack of distal spreading of alveolar smooth muscle cell progenitors during lung development. Development. 1997 Oct;124(20):3943-53 |
1 | J:321068 Maimets M, Pedersen MT, Guiu J, Dreier J, Thodberg M, Antoku Y, Schweiger PJ, Rib L, Bressan RB, Miao Y, Garcia KC, Sandelin A, Serup P, Jensen KB, Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling. Nat Commun. 2022 Feb 7;13(1):715 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
1 | J:352884 Miura A, Sarmah H, Tanaka J, Hwang Y, Sawada A, Shimamura Y, Otoshi T, Kondo Y, Fang Y, Shimizu D, Ninish Z, Suer JL, Dubois NC, Davis J, Toyooka S, Wu J, Que J, Hawkins FJ, Lin CS, Mori M, Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes the generation of the whole lung. Elife. 2023 Oct 20;12 |
1 | J:44830 Ogura Y, Takakura N, Yoshida H, Nishikawa SI, Essential role of platelet-derived growth factor receptor alpha in the development of the intraplacental yolk sac/sinus of Duval in mouse placenta. Biol Reprod. 1998 Jan;58(1):65-72 |
1 | J:242339 Ohayon D, Garces A, Joly W, Soukkarieh C, Takagi T, Sabourin JC, Agius E, Darling DS, De Santa Barbara P, Higashi Y, Stolt CC, Hugnot JP, Richardson WD, Carroll P, Pattyn A, Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Cell Rep. 2016 Nov 01;17(6):1473-1481 |
1 | J:187102 Ortega MC, Bribian A, Peregrin S, Gil MT, Marin O, de Castro F, Neuregulin-1/ErbB4 signaling controls the migration of oligodendrocyte precursor cells during development. Exp Neurol. 2012 Jun;235(2):610-20 |
1* | J:45679 Peterson RS, Lim L, Ye H, Zhou H, Overdier DG, Costa RH, The winged helix transcriptional activator HFH-8 is expressed in the mesoderm of the primitive streak stage of mouse embryos and its cellular derivatives. Mech Dev. 1997 Dec;69(1-2):53-69 |
1 | J:92200 Popova SN, Rodriguez-Sanchez B, Liden A, Betsholtz C, Van Den Bos T, Gullberg D, The mesenchymal alpha11beta1 integrin attenuates PDGF-BB-stimulated chemotaxis of embryonic fibroblasts on collagens. Dev Biol. 2004 Jun 15;270(2):427-42 |
1* | J:84432 Qi Y, Tan M, Hui CC, Qiu M, Gli2 is required for normal Shh signaling and oligodendrocyte development in the spinal cord. Mol Cell Neurosci. 2003 Jul;23(3):440-50 |
1* | J:73068 Spassky N, Heydon K, Mangatal A, Jankovski A, Olivier C, Queraud-Lesaux F, Goujet-Zalc C, Thomas JL, Zalc B, Sonic hedgehog-dependent emergence of oligodendrocytes in the telencephalon: evidence for a source of oligodendrocytes in the olfactory bulb that is independent of PDGFRalpha signaling. Development. 2001 Dec;128(24):4993-5004 |
1 | J:84301 Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M, The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 2003 Jul 1;17(13):1677-89 |
2 | J:74258 Stolt CC, Rehberg S, Ader M, Lommes P, Riethmacher D, Schachner M, Bartsch U, Wegner M, Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev. 2002 Jan 15;16(2):165-70 |
1 | J:116148 Stolt CC, Schlierf A, Lommes P, Hillgartner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M, SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell. 2006 Nov;11(5):697-709 |
1* | J:98585 Stolt CC, Schmitt S, Lommes P, Sock E, Wegner M, Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord. Dev Biol. 2005 May 15;281(2):309-17 |
1 | J:107228 Sun T, Hafler BP, Kaing S, Kitada M, Ligon KL, Widlund HR, Yuk DI, Stiles CD, Rowitch DH, Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube. Dev Biol. 2006 Apr 1;292(1):152-64 |
1 | J:144194 Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72 |
1 | J:36077 Takakura N, Yoshida H, Kunisada T, Nishikawa S, Nishikawa SI, Involvement of platelet-derived growth factor receptor-alpha in hair canal formation [comment]. J Invest Dermatol. 1996 Nov;107(5):770-7 |
2* | J:40647 Takakura N, Yoshida H, Ogura Y, Kataoka H, Nishikawa S, Nishikawa S, PDGFR alpha expression during mouse embryogenesis: immunolocalization analyzed by whole-mount immunohistostaining using the monoclonal anti-mouse PDGFR alpha antibody APA5. J Histochem Cytochem. 1997 Jun;45(6):883-93 |
1* | J:70747 Tekki-Kessaris N, Woodruff R, Hall AC, Gaffield W, Kimura S, Stiles CD, Rowitch DH, Richardson WD, Hedgehog-dependent oligodendrocyte lineage specification in the telencephalon. Development. 2001 Jul;128(13):2545-54 |
1* | J:91730 Verma-Kurvari S, Parada LF, Identification of tyrosine kinases expressed in the male mouse gubernaculum during development. Dev Dyn. 2004 Aug;230(4):660-5 |
1* | J:337458 Waldhauser V, Baroti T, Frob F, Wegner M, PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12) |
1* | J:288669 Wedel M, Frob F, Elsesser O, Wittmann MT, Lie DC, Reis A, Wegner M, Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation. Nucleic Acids Res. 2020 May 21;48(9):4839-4857 |
1 | J:340973 Wojahn I, Ludtke TH, Christoffels VM, Trowe MO, Kispert A, TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung. Respir Res. 2019 Dec 23;20(1):292 |
1 | J:105927 Wu S, Wu Y, Capecchi MR, Motoneurons and oligodendrocytes are sequentially generated from neural stem cells but do not appear to share common lineage-restricted progenitors in vivo. Development. 2006 Feb;133(4):581-90 |
1 | J:95139 Xu X, Bringas P Jr, Soriano P, Chai Y, PDGFR-alpha signaling is critical for tooth cusp and palate morphogenesis. Dev Dyn. 2005 Jan;232(1):75-84 |
1 | J:152576 Ye F, Chen Y, Hoang T, Montgomery RL, Zhao XH, Bu H, Hu T, Taketo MM, van Es JH, Clevers H, Hsieh J, Bassel-Duby R, Olson EN, Lu QR, HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci. 2009 Jul;12(7):829-38 |
1 | J:193501 Yu Y, Chen Y, Kim B, Wang H, Zhao C, He X, Liu L, Liu W, Wu LM, Mao M, Chan JR, Wu J, Lu QR, Olig2 targets chromatin remodelers to enhancers to initiate oligodendrocyte differentiation. Cell. 2013 Jan 17;152(1-2):248-61 |
1 | J:325092 Zhen Y, Cullen CL, Ricci R, Summers BS, Rehman S, Ahmed ZM, Foster AY, Emery B, Gasperini R, Young KM, Protocadherin 15 suppresses oligodendrocyte progenitor cell proliferation and promotes motility through distinct signalling pathways. Commun Biol. 2022 May 30;5(1):511 |
1 | J:208340 Zhu Q, Zhao X, Zheng K, Li H, Huang H, Zhang Z, Mastracci T, Wegner M, Chen Y, Sussel L, Qiu M, Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS. Development. 2014 Feb;141(3):548-55 |
1 | J:168041 Zhu Y, Park J, Hu X, Zheng K, Li H, Cao Q, Feng GS, Qiu M, Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase. Glia. 2010 Sep;58(12):1407-14 |
Pdgfrb platelet derived growth factor receptor, beta polypeptide (Synonyms: CD140b, Pdgfr) | |
Results | Reference |
1 | J:219809 Afelik S, Pool B, Schmerr M, Penton C, Jensen J, Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development. Dev Biol. 2015 Mar 15;399(2):204-17 |
2 | J:196361 Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnani MG, Messina G, Cossu G, Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory. Dev Cell. 2013 Mar 25;24(6):586-99 |
1 | J:236848 Chen Q, Zhang H, Liu Y, Adams S, Eilken H, Stehling M, Corada M, Dejana E, Zhou B, Adams RH, Endothelial cells are progenitors of cardiac pericytes and vascular smooth muscle cells. Nat Commun. 2016 Aug 12;7:12422 |
1 | J:346123 Darrigrand JF, Salowka A, Torres-Cano A, Tapia-Rojo R, Zhu T, Garcia-Manyes S, Spagnoli FM, Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner. Dev Cell. 2024 Feb 5;59(3):326-338.e5 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1 | J:228882 Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS, Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016 Jan 1;409(1):218-33 |
1* | J:308556 Goss G, Rognoni E, Salameti V, Watt FM, Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair. Front Cell Dev Biol. 2021;9:675080 |
1 | J:189818 Haege S, Einer C, Thiele S, Mueller W, Nietzsche S, Lupp A, Mackay F, Schulz S, Stumm R, CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney. PLoS One. 2012;7(8):e42814 |
1 | J:293063 Hamashima T, Ishii Y, Nguyen LQ, Okuno N, Sang Y, Matsushima T, Kurashige Y, Takebayashi H, Mori H, Fujimori T, Yamamoto S, Sasahara M, Oligodendrogenesis and Myelin Formation in the Forebrain Require Platelet-derived Growth Factor Receptor-alpha. Neuroscience. 2020 Jun 1;436:11-26 |
1 | J:20328 Hellstrom M, Kal n M, Lindahl P, Abramsson A, Betsholtz C, Role of PDGF-B and PDGFR-beta in recruitment of vascular smooth muscle cells and pericytes during embryonic blood vessel formation in the mouse. Development. 1999 Jun;126(14):3047-55 |
1* | J:95138 Inanlou MR, Kablar B, Abnormal development of the intercostal muscles and the rib cage in Myf5-/- embryos leads to pulmonary hypoplasia. Dev Dyn. 2005 Jan;232(1):43-54 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:174022 Jeansson M, Gawlik A, Anderson G, Li C, Kerjaschki D, Henkelman M, Quaggin SE, Angiopoietin-1 is essential in mouse vasculature during development and in response to injury. J Clin Invest. 2011 Jun 1;121(6):2278-89 |
1 | J:257184 Leid J, Carrelha J, Boukarabila H, Epelman S, Jacobsen SE, Lavine KJ, Primitive Embryonic Macrophages are Required for Coronary Development and Maturation. Circ Res. 2016 May 13;118(10):1498-511 |
1 | J:325446 Lepiemme F, Stoufflet J, Javier-Torrent M, Mazzucchelli G, Silva CG, Nguyen L, Oligodendrocyte precursors guide interneuron migration by unidirectional contact repulsion. Science. 2022 May 20;376(6595):eabn6204 |
1 | J:50064 Lindahl P, Hellstrom M, Kalen M, Karlsson L, Pekny M, Pekna M, Soriano P, Betsholtz C, Paracrine PDGF-B/PDGF-Rbeta signaling controls mesangial cell development in kidney glomeruli. Development. 1998 Sep;125(17):3313-22 |
1 | J:335167 Lu P, Wu B, Wang Y, Russell M, Liu Y, Bernard DJ, Zheng D, Zhou B, Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis. Dev Cell. 2023 Mar 29; |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:241849 Ma S, Santhosh D, Kumar T P, Huang Z, A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis. Dev Cell. 2017 May 22;41(4):366-381.e4 |
1* | J:67157 McCright B, Gao X, Shen L, Lozier J, Lan Y, Maguire M, Herzlinger D, Weinmaster G, Jiang R, Gridley T, Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development. 2001 Feb;128(4):491-502 |
1 | J:352884 Miura A, Sarmah H, Tanaka J, Hwang Y, Sawada A, Shimamura Y, Otoshi T, Kondo Y, Fang Y, Shimizu D, Ninish Z, Suer JL, Dubois NC, Davis J, Toyooka S, Wu J, Que J, Hawkins FJ, Lin CS, Mori M, Conditional blastocyst complementation of a defective Foxa2 lineage efficiently promotes the generation of the whole lung. Elife. 2023 Oct 20;12 |
1 | J:321844 Mochida Y, Ochiai K, Nagase T, Nonomura K, Akimoto Y, Fukuhara H, Sakai T, Matsumura G, Yamaguchi Y, Nagase M, Piezo2 expression and its alteration by mechanical forces in mouse mesangial cells and renin-producing cells. Sci Rep. 2022 Mar 10;12(1):4197 |
1 | J:329397 Nadeem T, Bommareddy A, Bolarinwa L, Cuervo H, Pericyte dynamics in the mouse germinal matrix angiogenesis. FASEB J. 2022 Jun;36(6):e22339 |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
1 | J:117504 Ponten A, Folestad EB, Pietras K, Eriksson U, Platelet-derived growth factor D induces cardiac fibrosis and proliferation of vascular smooth muscle cells in heart-specific transgenic mice. Circ Res. 2005 Nov 11;97(10):1036-45 |
1* | J:17448 Shinbrot E, Peters KG, Williams LT, Expression of the platelet-derived growth factor beta receptor during organogenesis and tissue differentiation in the mouse embryo. Dev Dyn. 1994 Mar;199(3):169-75 |
1 | J:233746 Wang X, Wang Y, Snitow ME, Stewart KM, Li S, Lu M, Morrisey EE, Expression of histone deacetylase 3 instructs alveolar type I cell differentiation by regulating a Wnt signaling niche in the lung. Dev Biol. 2016 Jun 15;414(2):161-9 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:340973 Wojahn I, Ludtke TH, Christoffels VM, Trowe MO, Kispert A, TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung. Respir Res. 2019 Dec 23;20(1):292 |
1 | J:361729 Yang G, He Q, Guo X, Li RY, Lin J, Lang Y, Tao W, Liu W, Lin H, Xing S, Qi Y, Xie Z, Han JJ, Zhou B, Teng Y, Yang X, Identification of the metaphyseal skeletal stem cell building trabecular bone. Sci Adv. 2024 Feb 23;10(8):eadl2238 |
1 | J:352471 Yoshida S, Tsuneoka Y, Tsukada T, Nakakura T, Kawamura A, Kai W, Yoshida K, Primary Cilia are Required for Cell-Type Determination and Angiogenesis in Pituitary Development. Endocrinology. 2024 Jul 1;165(8) |
Pdia2 protein disulfide isomerase associated 2 (Synonyms: 1810041F13Rik, Pdip, Pdipl) | |
Results | Reference |
2* | J:168632 Firtina Z, Duncan MK, Unfolded Protein Response (UPR) is activated during normal lens development. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):135-43 |
Pdia3 protein disulfide isomerase associated 3 (Synonyms: Erp, ERp57, ERp60, ERp61, Grp58, PDI, PDI-Q2, Plca) | |
Results | Reference |
1 | J:270164 Guo M, Du Y, Gokey JJ, Ray S, Bell SM, Adam M, Sudha P, Perl AK, Deshmukh H, Potter SS, Whitsett JA, Xu Y, Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth. Nat Commun. 2019 Jan 3;10(1):37 |
1 | J:128422 Zhang X, Szabo E, Michalak M, Opas M, Endoplasmic reticulum stress during the embryonic development of the central nervous system in the mouse. Int J Dev Neurosci. 2007 Nov;25(7):455-63 |
Pdia4 protein disulfide isomerase associated 4 (Synonyms: Cai, Erp72, ERp72, U48620) | |
Results | Reference |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
Pdk1 pyruvate dehydrogenase kinase, isoenzyme 1 (Synonyms: D530020C15Rik) | |
Results | Reference |
1* | J:314146 Gao W, Zhang Y, Luo H, Niu M, Zheng X, Hu W, Cui J, Xue X, Bo Y, Dai F, Lu Y, Yang D, Guo Y, Guo H, Li H, Zhang Y, Yang T, Li L, Zhang L, Hou R, Wen S, An C, Ma T, Jin L, Xu W, Wu Y, Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis. Cell Death Dis. 2020 Oct 26;11(10):919 |
Pdlim3 PDZ and LIM domain 3 (Synonyms: ALP) | |
Results | Reference |
2 | J:329949 Yuan H, Xie B, Yu X, Lin C, Li M, Zhang Y, Zou X, Lu M, Zhao M, Wen X, A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development. Front Physiol. 2022;13:981311 |
Pdlim7 PDZ and LIM domain 7 (Synonyms: 1110003B01Rik, 2410002J21Rik, Enigma) | |
Results | Reference |
1* | J:166643 Fang P, Wang X, Zhang L, Yuan G, Chen Z, Zhang Q, Immunohistochemical localization of LIM mineralization protein 1 during mouse molar development. J Mol Histol. 2010 Oct;41(4-5):199-203 |
Pdpk1 3-phosphoinositide dependent protein kinase 1 (Synonyms: Pdk1, Pkb kinase) | |
Results | Reference |
1 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
1 | J:305176 Wei Y, Han X, Zhao C, PDK1 regulates the survival of the developing cortical interneurons. Mol Brain. 2020 May 4;13(1):65 |
Pdpn podoplanin (Synonyms: Gp38, OTS-8, PA2.26, RANDAM-2, T1a, T1alpha) | |
Results | Reference |
1 | J:159868 Benezech C, White A, Mader E, Serre K, Parnell S, Pfeffer K, Ware CF, Anderson G, Caamano JH, Ontogeny of stromal organizer cells during lymph node development. J Immunol. 2010 Apr 15;184(8):4521-30 |
1 | J:276488 Bilodeau M, Shojaie S, Ackerley C, Post M, Rossant J, Identification of a proximal progenitor population from murine fetal lungs with clonogenic and multilineage differentiation potential. Stem Cell Reports. 2014 Oct 14;3(4):634-49 |
1 | J:316183 Cai Y, Yoneda M, Tomita T, Kurotani R, Okamoto M, Kido T, Abe H, Mitzner W, Guha A, Kimura S, Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice. BMC Pulm Med. 2015 Jul 16;15:72 |
1* | J:291486 Daniel E, Barlow HR, Sutton GI, Gu X, Htike Y, Cowdin MA, Cleaver O, Cyp26b1 is an essential regulator of distal airway epithelial differentiation during lung development. Development. 2020 Feb 20;147(4):dev181560 |
1 | J:207561 Dellinger MT, Meadows SM, Wynne K, Cleaver O, Brekken RA, Vascular endothelial growth factor receptor-2 promotes the development of the lymphatic vasculature. PLoS One. 2013;8(9):e74686 |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:247780 Fujimoto J, Nunomura-Nakamura S, Liu Y, Lang W, McDowell T, Jakubek Y, Ezzeddine D, Kapere Ochieng J, Petersen J, Davies G, Fukuoka J, Wistuba II, Ehli E, Fowler J, Scheet P, Kadara H, Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a. Int J Cancer. 2017 Oct 15;141(8):1589-1599 |
1* | J:293098 Jafree DJ, Moulding D, Kolatsi-Joannou M, Perretta Tejedor N, Price KL, Milmoe NJ, Walsh CL, Correra RM, Winyard PJ, Harris PC, Ruhrberg C, Walker-Samuel S, Riley PR, Woolf AS, Scambler PJ, Long DA, Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease. Elife. 2019 Dec 6;8:e48183 |
1 | J:329963 Janardhan HP, Dresser K, Hutchinson L, Trivedi CM, Pathological MAPK activation-mediated lymphatic basement membrane disruption causes lymphangiectasia that is treatable with ravoxertinib. JCI Insight. 2022 Sep 8;7(17):e153033 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:237343 Laresgoiti U, Nikolic MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL, Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016 Oct 15;143(20):3686-3699 |
1 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:284120 Mahamud MR, Geng X, Ho YC, Cha B, Kim Y, Ma J, Chen L, Myers G, Camper S, Mustacich D, Witte M, Choi D, Hong YK, Chen H, Varshney G, Engel JD, Wang S, Kim TH, Lim KC, Srinivasan RS, GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126. Development. 2019 Nov 5;146(21):dev184218 |
1 | J:262023 Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K, Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling. Circ Res. 2017 Apr 14;120(8):1276-1288 |
1 | J:231667 Munger SJ, Geng X, Srinivasan RS, Witte MH, Paul DL, Simon AM, Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice. Dev Biol. 2016 Apr 15;412(2):173-90 |
1 | J:275825 Norman TA Jr, Gower AC, Chen F, Fine A, Transcriptional landscape of pulmonary lymphatic endothelial cells during fetal gestation. PLoS One. 2019;14(5):e0216795 |
1 | J:263065 Ogawa T, Li Y, Lua I, Hartner A, Asahina K, Isolation of a unique hepatic stellate cell population expressing integrin alpha8 from embryonic mouse livers. Dev Dyn. 2018 Jun;247(6):867-881 |
1 | J:338969 Shi CY, Elcavage LE, Chivukula RR, Stefano J, Kleaveland B, Bartel DP, ZSWIM8 destabilizes many murine microRNAs and is required for proper embryonic growth and development. Genome Res. 2023 Aug 2; |
1 | J:290284 Shrestha A, Carraro G, Nottet N, Vazquez-Armendariz AI, Herold S, Cordero J, Singh I, Wilhelm J, Barreto G, Morty R, El Agha E, Mari B, Chen C, Zhang JS, Chao CM, Bellusci S, A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development. Cell Mol Life Sci. 2019 Jul;76(14):2817-2832 |
2 | J:217677 Snitow ME, Li S, Morley MP, Rathi K, Lu MM, Kadzik RS, Stewart KM, Morrisey EE, Ezh2 represses the basal cell lineage during lung endoderm development. Development. 2015 Jan 1;142(1):108-17 |
1 | J:177488 Srinivasan RS, Oliver G, Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves. Genes Dev. 2011 Oct 15;25(20):2187-97 |
1 | J:239521 Stzepourginski I, Nigro G, Jacob JM, Dulauroy S, Sansonetti PJ, Eberl G, Peduto L, CD34+ mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E506-E513 |
1 | J:363523 Sun X, Malandraki-Miller S, Kennedy T, Bassat E, Klaourakis K, Zhao J, Gamen E, Vieira JM, Tzahor E, Riley PR, The extracellular matrix protein agrin is essential for epicardial epithelial-to-mesenchymal transition during heart development. Development. 2021 May 1;148(9) |
1 | J:266086 Tsukiji N, Inoue O, Morimoto M, Tatsumi N, Nagatomo H, Ueta K, Shirai T, Sasaki T, Otake S, Tamura S, Tachibana T, Okabe M, Hirashima M, Ozaki Y, Suzuki-Inoue K, Platelets play an essential role in murine lung development through Clec-2/podoplanin interaction. Blood. 2018 Sep 13;132(11):1167-1179 |
1 | J:336858 Vallecillo-Garcia P, Orgeur M, Comai G, Poehle-Kronnawitter S, Fischer C, Gloger M, Dumas CE, Giesecke-Thiel C, Sauer S, Tajbakhsh S, Hopken UE, Stricker S, A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation. Immunity. 2023 Jun 13;56(6):1204-1219.e8 |
1 | J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34 |
1 | J:196696 Zou Z, Enis DR, Bui H, Khandros E, Kumar V, Jakus Z, Thom C, Yang Y, Dhillon V, Chen M, Lu M, Weiss MJ, Kahn ML, The secreted lymphangiogenic factor CCBE1 is essential for fetal liver erythropoiesis. Blood. 2013 Apr 18;121(16):3228-36 |
Pdx1 pancreatic and duodenal homeobox 1 (Synonyms: IDX-1, Ipf1, IPF-1, Mody4, pdx-1, STF-1) | |
Results | Reference |
1* | J:85764 Annicotte JS, Fayard E, Swift GH, Selander L, Edlund H, Tanaka T, Kodama T, Schoonjans K, Auwerx J, Pancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas development. Mol Cell Biol. 2003 Oct;23(19):6713-24 |
1 | J:119565 Boyer DF, Fujitani Y, Gannon M, Powers AC, Stein RW, Wright CV, Complementation rescue of Pdx1 null phenotype demonstrates distinct roles of proximal and distal cis-regulatory sequences in pancreatic and duodenal expression. Dev Biol. 2006 Oct 15;298(2):616-31 |
1 | J:307544 Burtscher I, Tarquis-Medina M, Salinno C, Schirge S, Beckenbauer J, Bakhti M, Lickert H, Generation of a Novel Nkx6-1 Venus Fusion Reporter Mouse Line. Int J Mol Sci. 2021 Mar 26;22(7) |
1* | J:165268 Claiborn KC, Sachdeva MM, Cannon CE, Groff DN, Singer JD, Stoffers DA, Pcif1 modulates Pdx1 protein stability and pancreatic beta cell function and survival in mice. J Clin Invest. 2010 Oct 1;120(10):3713-21 |
1 | J:267596 Escot S, Willnow D, Naumann H, Di Francescantonio S, Spagnoli FM, Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors. Nat Commun. 2018 Nov 30;9(1):5082 |
1 | J:89720 Fajas L, Annicotte JS, Miard S, Sarruf D, Watanabe M, Auwerx J, Impaired pancreatic growth, beta cell mass, and beta cell function in E2F1 (-/- )mice. J Clin Invest. 2004 May;113(9):1288-95 |
1 | J:104617 Fujitani Y, Fujitani S, Boyer DF, Gannon M, Kawaguchi Y, Ray M, Shiota M, Stein RW, Magnuson MA, Wright CV, Targeted deletion of a cis-regulatory region reveals differential gene dosage requirements for Pdx1 in foregut organ differentiation and pancreas formation. Genes Dev. 2006 Jan 15;20(2):253-66 |
1 | J:182863 Gao N, Le Lay J, Qin W, Doliba N, Schug J, Fox AJ, Smirnova O, Matschinsky FM, Kaestner KH, Foxa1 and Foxa2 maintain the metabolic and secretory features of the mature beta-cell. Mol Endocrinol. 2010 Aug;24(8):1594-604 |
1 | J:193959 Georgia S, Kanji M, Bhushan A, DNMT1 represses p53 to maintain progenitor cell survival during pancreatic organogenesis. Genes Dev. 2013 Feb 15;27(4):372-7 |
1* | J:191140 Grigoryan M, Kedees MH, Guz Y, Teitelman G, Phenotype of entero-endocrine L cells becomes restricted during development. Dev Dyn. 2012 Dec;241(12):1986-92 |
1* | J:22553 Guz Y, Montminy MR, Stein R, Leonard J, Gamer LW, Wright CV, Teitelman G, Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny. Development. 1995 Jan;121(1):11-8 |
1* | J:110137 Holland AM, Micallef SJ, Li X, Elefanty AG, Stanley EG, A mouse carrying the green fluorescent protein gene targeted to the Pdx1 locus facilitates the study of pancreas development and function. Genesis. 2006 Jun;44(6):304-7 |
1 | J:263185 Huang M, He H, Belenkaya T, Lin X, Multiple roles of epithelial heparan sulfate in stomach morphogenesis. J Cell Sci. 2018 May 29;131(10):jcs210781 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1 | J:154990 Kang HS, Kim YS, ZeRuth G, Beak JY, Gerrish K, Kilic G, Sosa-Pineda B, Jensen J, Foley J, Jetten AM, Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression. Mol Cell Biol. 2009 Dec;29(24):6366-79 |
1 | J:257425 Kim DS, Song L, Wang J, Wu H, Gu G, Sugi Y, Li Z, Wang H, GRP94 Is an Essential Regulator of Pancreatic beta-Cell Development, Mass, and Function in Male Mice. Endocrinology. 2018 Feb 1;159(2):1062-1073 |
1 | J:250031 Kodama S, Nakano Y, Hirata K, Furuyama K, Horiguchi M, Kuhara T, Masui T, Kawaguchi M, Gannon M, Wright CV, Uemoto S, Kawaguchi Y, Diabetes Caused by Elastase-Cre-Mediated Pdx1 Inactivation in Mice. Sci Rep. 2016 Feb 18;6:21211 |
1 | J:272578 Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G, Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. Dev Cell. 2019 Jan 7;48(1):49-63.e7 |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
1* | J:32017 Offield MF, Jetton TL, Labosky PA, Ray M, Stein RW, Magnuson MA, Hogan BL, Wright CV, PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development. 1996 Mar;122(3):983-95 |
1* | J:235223 Omori H, Ogaki S, Sakano D, Sato M, Umeda K, Takeda N, Nakagata N, Kume S, Changes in expression of C2cd4c in pancreatic endocrine cells during pancreatic development. FEBS Lett. 2016 Aug;590(16):2584-93 |
1 | J:191071 Petzold KM, Naumann H, Spagnoli FM, Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas. Development. 2013 Jan 1;140(1):126-35 |
1* | J:246476 Raum JC, Soleimanpour SA, Groff DN, Core N, Fasano L, Garratt AN, Dai C, Powers AC, Stoffers DA, Tshz1 Regulates Pancreatic beta-Cell Maturation. Diabetes. 2015 Aug;64(8):2905-14 |
1 | J:208409 Reinert RB, Cai Q, Hong JY, Plank JL, Aamodt K, Prasad N, Aramandla R, Dai C, Levy SE, Pozzi A, Labosky PA, Wright CV, Brissova M, Powers AC, Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding. Development. 2014 Apr;141(7):1480-91 |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
2 | J:151981 Spence JR, Lange AW, Lin SC, Kaestner KH, Lowy AM, Kim I, Whitsett JA, Wells JM, Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell. 2009 Jul;17(1):62-74 |
1 | J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521 |
1 | J:166759 Villasenor A, Chong DC, Henkemeyer M, Cleaver O, Epithelial dynamics of pancreatic branching morphogenesis. Development. 2010 Dec;137(24):4295-305 |
1 | J:136131 Wang S, Hecksher-Sorensen J, Xu Y, Zhao A, Dor Y, Rosenberg L, Serup P, Gu G, Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation. Dev Biol. 2008 May 15;317(2):531-40 |
1 | J:362739 Wu Y, Qin K, Xu Y, Rajhans S, Vo T, Lopez KM, Liu J, Nipper MH, Deng J, Yin X, Ramjit LR, Ye Z, Luan Y, Arda HE, Wang P, Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation. Elife. 2024 Jul 25;13 |
Pdyn prodynorphin (Synonyms: Dyn) | |
Results | Reference |
1 | J:119559 Bouwman J, Spijker S, Schut D, Wachtler B, Ylstra B, Smit AB, Verhage M, Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse. J Neurochem. 2006 Oct;99(1):84-96 |
1 | J:142008 Huang M, Huang T, Xiang Y, Xie Z, Chen Y, Yan R, Xu J, Cheng L, Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons. Dev Biol. 2008 Jul 2;322(2):394-405 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
1* | J:57437 Sharifi N, Ament M, Brennan MB, Hochgeschwender U, Isolation and characterization of the mouse homolog of the preprodynorphin (Pdyn) gene. Neuropeptides. 1999 Jun;33(3):236-8 |
1 | J:238868 Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z, The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 2016 Aug 02;16(5):1431-44 |
Pdzrn3 PDZ domain containing RING finger 3 (Synonyms: 1110020C07Rik, LNX3, semaphorin cytoplasmic domain-associated protein 3A, Semcap3) | |
Results | Reference |
1* | J:134925 Lu Z, Je HS, Young P, Gross J, Lu B, Feng G, Regulation of synaptic growth and maturation by a synapse-associated E3 ubiquitin ligase at the neuromuscular junction. J Cell Biol. 2007 Jun 18;177(6):1077-89 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
Pecam1 platelet/endothelial cell adhesion molecule 1 (Synonyms: Cd31, PECAM-1) | |
Results | Reference |
1 | J:226941 Akerberg BN, Sarangam ML, Stankunas K, Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Dev Biol. 2015 Nov 1;407(1):158-72 |
1 | J:362029 Anjum H, Smith JP, Martini AG, Yacu GS, Medrano S, Gomez RA, Sequeira-Lopez MLS, Quaggin SE, Finer G, Tcf21 as a founder transcription factor in specifying Foxd1 cells to the juxtaglomerular cell lineage. Am J Physiol Renal Physiol. 2025 Jan 1;328(1):F121-F130 |
1 | J:284333 Arai HN, Sato F, Yamamoto T, Woltjen K, Kiyonari H, Yoshimoto Y, Shukunami C, Akiyama H, Kist R, Sehara-Fujisawa A, Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate. Cell Rep. 2019 Oct 15;29(3):603-616.e5 |
1 | J:263978 Ariza L, Canete A, Rojas A, Munoz-Chapuli R, Carmona R, Role of the Wilms' tumor suppressor gene Wt1 in pancreatic development. Dev Dyn. 2018 Apr 30; |
1 | J:356098 Bar O, Gelb S, Atamny K, Anzi S, Ben-Zvi A, Angiomodulin (IGFBP7) is a cerebral specific angiocrine factor, but is probably not a blood-brain barrier inducer. Fluids Barriers CNS. 2020 Apr 1;17(1):27 |
1 | J:237340 Ben Shoham A, Rot C, Stern T, Krief S, Akiva A, Dadosh T, Sabany H, Lu Y, Kadler KE, Zelzer E, Deposition of collagen type I onto skeletal endothelium reveals a new role for blood vessels in regulating bone morphology. Development. 2016 Nov 01;143(21):3933-3943 |
1* | J:99531 Benedito R, Duarte A, Expression of Dll4 during mouse embryogenesis suggests multiple developmental roles. Gene Expr Patterns. 2005 Aug;5(6):750-5 |
1* | J:171712 Bird AD, Flecknoe SJ, Tan KH, Olsson PF, Antony N, Mantamadiotis T, Hooper SB, Cole TJ, cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development. PLoS One. 2011;6(3):e17843 |
1* | J:30623 Breier G, Breviario F, Caveda L, Berthier R, Schnurch H, Gotsch U, Vestweber D, Risau W, Dejana E, Molecular cloning and expression of murine vascular endothelial-cadherin in early stage development of cardiovascular system. (Errata: vol. 88(3):1129-33). Blood. 1996 Jan 15;87(2):630-41 |
1 | J:116552 Brissova M, Shostak A, Shiota M, Wiebe PO, Poffenberger G, Kantz J, Chen Z, Carr C, Jerome WG, Chen J, Baldwin HS, Nicholson W, Bader DM, Jetton T, Gannon M, Powers AC, Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function. Diabetes. 2006 Nov;55(11):2974-85 |
1* | J:229936 Cano E, Carmona R, Ruiz-Villalba A, Rojas A, Chau YY, Wagner KD, Wagner N, Hastie ND, Munoz-Chapuli R, Perez-Pomares JM, Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):656-61 |
1 | J:359854 Cano-Carrillo S, Garcia-Padilla C, Aranega AE, Lozano-Velasco E, Franco D, Mef2c- and Nkx2-5-Divergent Transcriptional Regulation of Chick WT1_76127 and Mouse Gm14014 lncRNAs and Their Implication in Epicardial Cell Migration. Int J Mol Sci. 2024 Nov 30;25(23) |
1 | J:196361 Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnani MG, Messina G, Cossu G, Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory. Dev Cell. 2013 Mar 25;24(6):586-99 |
1 | J:192176 Casanova JC, Travisano S, de la Pompa JL, Epithelial-to-mesenchymal transition in epicardium is independent of snail1. Genesis. 2013 Jan;51(1):32-40 |
1 | J:233304 Cha B, Geng X, Mahamud MR, Fu J, Mukherjee A, Kim Y, Jho EH, Kim TH, Kahn ML, Xia L, Dixon JB, Chen H, Srinivasan RS, Mechanotransduction activates canonical Wnt/beta-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves. Genes Dev. 2016 Jun 15;30(12):1454-69 |
2 | J:269779 Cha B, Geng X, Mahamud MR, Zhang JY, Chen L, Kim W, Jho EH, Kim Y, Choi D, Dixon JB, Chen H, Hong YK, Olson L, Kim TH, Merrill BJ, Davis MJ, Srinivasan RS, Complementary Wnt Sources Regulate Lymphatic Vascular Development via PROX1-Dependent Wnt/beta-Catenin Signaling. Cell Rep. 2018 Oct 16;25(3):571-584.e5 |
1 | J:301556 Cha B, Ho YC, Geng X, Mahamud MR, Chen L, Kim Y, Choi D, Kim TH, Randolph GJ, Cao X, Chen H, Srinivasan RS, YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling. Development. 2020 Dec 13;147(23):dev195453 |
1 | J:183485 Chen D, Jarrell A, Guo C, Lang R, Atit R, Dermal beta-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation. Development. 2012 Apr;139(8):1522-33 |
1 | J:227058 Chen D, Wang X, Liang D, Gordon J, Mittal A, Manley N, Degenhardt K, Astrof S, Fibronectin signals through integrin alpha5beta1 to regulate cardiovascular development in a cell type-specific manner. Dev Biol. 2015 Nov 15;407(2):195-210 |
1 | J:208766 Chen J, Tu X, Esen E, Joeng KS, Lin C, Arbeit JM, Ruegg MA, Hall MN, Ma L, Long F, WNT7B promotes bone formation in part through mTORC1. PLoS Genet. 2014 Jan;10(1):e1004145 |
1 | J:339854 Chen SY, Liu FC, The Fgf9-Nolz1-Wnt2 axis regulates morphogenesis of the lung. Development. 2023 Aug 15;150(16):dev201827 |
1* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:218538 Coskun S, Chao H, Vasavada H, Heydari K, Gonzales N, Zhou X, de Crombrugghe B, Hirschi KK, Development of the fetal bone marrow niche and regulation of HSC quiescence and homing ability by emerging osteolineage cells. Cell Rep. 2014 Oct 23;9(2):581-90 |
1 | J:126065 Costa MR, Kessaris N, Richardson WD, Gotz M, Hedin-Pereira C, The marginal zone/layer I as a novel niche for neurogenesis and gliogenesis in developing cerebral cortex. J Neurosci. 2007 Oct 17;27(42):11376-88 |
1 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1* | J:264603 Da Silva F, Massa F, Motamedi FJ, Vidal V, Rocha AS, Gregoire EP, Cai CL, Wagner KD, Schedl A, Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4. Dev Biol. 2018 Sep 1;441(1):42-51 |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
1 | J:206101 Danussi C, Del Bel Belluz L, Pivetta E, Modica TM, Muro A, Wassermann B, Doliana R, Sabatelli P, Colombatti A, Spessotto P, EMILIN1/alpha9beta1 integrin interaction is crucial in lymphatic valve formation and maintenance. Mol Cell Biol. 2013 Nov;33(22):4381-94 |
1 | J:316298 Dejaeger M, Bohm AM, Dirckx N, Devriese J, Nefyodova E, Cardoen R, St-Arnaud R, Tournoy J, Luyten FP, Maes C, Integrin-Linked Kinase Regulates Bone Formation by Controlling Cytoskeletal Organization and Modulating BMP and Wnt Signaling in Osteoprogenitors. J Bone Miner Res. 2017 Oct;32(10):2087-2102 |
1 | J:273024 DiNuoscio G, Atit RP, Wnt/beta-catenin signaling in the mouse embryonic cranial mesenchyme is required to sustain the emerging differentiated meningeal layers. Genesis. 2019 Jan;57(1):e23279 |
1 | J:359863 Do LNH, Delgado E, Lim CG, Bkhache M, Peluzzo AM, Hua Y, Oza M, Mohsin S, Chen H, Autieri MV, Kim S, Liu X, A neuro-lymphatic communication guides lymphatic development by CXCL12 and CXCR4 signaling. Development. 2024 Nov 15;151(22) |
1 | J:190411 Dong Y, Zhang L, Zhang S, Bai Y, Chen H, Sun X, Yong W, Li W, Colvin SC, Rhodes SJ, Shou W, Zhang ZY, Phosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) and activating Akt protein. J Biol Chem. 2012 Sep 14;287(38):32172-9 |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:237001 Duan X, Bradbury SR, Olsen BR, Berendsen AD, VEGF stimulates intramembranous bone formation during craniofacial skeletal development. Matrix Biol. 2016 May-Jul;52-54:127-40 |
1 | J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82 |
1 | J:202337 Estrada KD, Wang W, Retting KN, Chien CT, Elkhoury FF, Heuchel R, Lyons KM, Smad7 regulates terminal maturation of chondrocytes in the growth plate. Dev Biol. 2013 Oct 15;382(2):375-84 |
1 | J:196018 Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W, Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell Rep. 2012 Jul 26;2(1):52-61 |
1 | J:346073 Farhat B, Bordeu I, Jagla B, Ibrahim S, Stefanovic S, Blanc H, Loulier K, Simons BD, Beaurepaire E, Livet J, Puceat M, Understanding the cell fate and behavior of progenitors at the origin of the mouse cardiac mitral valve. Dev Cell. 2024 Feb 5;59(3):339-350.e4 |
1 | J:307825 Fisher AL, Sangkhae V, Balusikova K, Palaskas NJ, Ganz T, Nemeth E, Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy. Nat Commun. 2021 Jun 29;12(1):4026 |
1 | J:215601 Gage PJ, Kuang C, Zacharias AL, The homeodomain transcription factor PITX2 is required for specifying correct cell fates and establishing angiogenic privilege in the developing cornea. Dev Dyn. 2014 Nov;243(11):1391-400 |
1 | J:266493 Gauvrit S, Villasenor A, Strilic B, Kitchen P, Collins MM, Marin-Juez R, Guenther S, Maischein HM, Fukuda N, Canham MA, Brickman JM, Bogue CW, Jayaraman PS, Stainier DYR, HHEX is a transcriptional regulator of the VEGFC/FLT4/PROX1 signaling axis during vascular development. Nat Commun. 2018 Jul 13;9(1):2704 |
1 | J:228882 Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS, Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016 Jan 1;409(1):218-33 |
1 | J:308918 Geng X, Yanagida K, Akwii RG, Choi D, Chen L, Ho Y, Cha B, Mahamud MR, Berman de Ruiz K, Ichise H, Chen H, Wythe JD, Mikelis CM, Hla T, Srinivasan RS, S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling. JCI Insight. 2020 Jul 23;5(14) |
1 | J:252755 Gillers BS, Chiplunkar A, Aly H, Valenta T, Basler K, Christoffels VM, Efimov IR, Boukens BJ, Rentschler S, Canonical wnt signaling regulates atrioventricular junction programming and electrophysiological properties. Circ Res. 2015 Jan 30;116(3):398-406 |
1* | J:260124 Goldmann T, Wieghofer P, Jordao MJ, Prutek F, Hagemeyer N, Frenzel K, Amann L, Staszewski O, Kierdorf K, Krueger M, Locatelli G, Hochgerner H, Zeiser R, Epelman S, Geissmann F, Priller J, Rossi FM, Bechmann I, Kerschensteiner M, Linnarsson S, Jung S, Prinz M, Origin, fate and dynamics of macrophages at central nervous system interfaces. Nat Immunol. 2016 Jul;17(7):797-805 |
1 | J:280117 Gong X, Guo X, Huang R, Liao H, Zhang Q, Yan J, Luo L, Zhang Q, Qiu A, Sun Y, Liang X, Expression of ILK in renal stroma is essential for multiple aspects of renal development. Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F374-F385 |
1 | J:330742 Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM, In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022 Oct 17;132(20):e156955 |
1 | J:173280 Goossens S, Janzen V, Bartunkova S, Yokomizo T, Drogat B, Crisan M, Haigh K, Seuntjens E, Umans L, Riedt T, Bogaert P, Haenebalcke L, Berx G, Dzierzak E, Huylebroeck D, Haigh JJ, The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization. Blood. 2011 May 26;117(21):5620-30 |
1* | J:137168 Gordon EJ, Gale NW, Harvey NL, Expression of the hyaluronan receptor LYVE-1 is not restricted to the lymphatic vasculature; LYVE-1 is also expressed on embryonic blood vessels. Dev Dyn. 2008 Jul;237(7):1901-9 |
2 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1* | J:308556 Goss G, Rognoni E, Salameti V, Watt FM, Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair. Front Cell Dev Biol. 2021;9:675080 |
1 | J:189012 Greif DM, Kumar M, Lighthouse JK, Hum J, An A, Ding L, Red-Horse K, Espinoza FH, Olson L, Offermanns S, Krasnow MA, Radial construction of an arterial wall. Dev Cell. 2012 Sep 11;23(3):482-93 |
1 | J:334094 Gu X, Heinrich A, Li SY, DeFalco T, Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions. Nat Commun. 2023 Mar 15;14(1):1439 |
1 | J:185218 Hall-Glenn F, De Young RA, Huang BL, van Handel B, Hofmann JJ, Chen TT, Choi A, Ong JR, Benya PD, Mikkola H, Iruela-Arispe ML, Lyons KM, CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PLoS One. 2012;7(2):e30562 |
1 | J:342844 Harvey AB, Wolters RA, Deepe RN, Tarolli HG, Drummond JR, Trouten A, Zandi A, Barth JL, Mukherjee R, Romeo MJ, Vaena SG, Tao G, Muise-Helmericks R, Ramos PS, Norris RA, Wessels A, Epicardial deletion of Sox9 leads to myxomatous valve degeneration and identifies Cd109 as a novel gene associated with valve development. J Mol Cell Cardiol. 2023 Nov 5;186:16-30 |
1 | J:217070 Hatch J, Mukouyama YS, Spatiotemporal mapping of vascularization and innervation in the fetal murine intestine. Dev Dyn. 2015 Jan;244(1):56-68 |
1 | J:159025 Hattori T, Muller C, Gebhard S, Bauer E, Pausch F, Schlund B, Bosl MR, Hess A, Surmann-Schmitt C, von der Mark H, de Crombrugghe B, von der Mark K, SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification. Development. 2010 Mar;137(6):901-11 |
1 | J:232449 He L, Tian X, Zhang H, Wythe JD, Zhou B, Fabp4-CreER lineage tracing reveals two distinctive coronary vascular populations. J Cell Mol Med. 2014 Nov;18(11):2152-6 |
1 | J:236411 He X, Ohba S, Hojo H, McMahon AP, AP-1 family members act with Sox9 to promote chondrocyte hypertrophy. Development. 2016 Aug 15;143(16):3012-23 |
1* | J:203907 Herrnberger L, Seitz R, Kuespert S, Bosl MR, Fuchshofer R, Tamm ER, Lack of endothelial diaphragms in fenestrae and caveolae of mutant Plvap-deficient mice. Histochem Cell Biol. 2012 Nov;138(5):709-24 |
1 | J:200722 Hick AC, Delmarcelle AS, Bouquet M, Klotz S, Copetti T, Forez C, Van Der Smissen P, Sonveaux P, Collet JF, Feron O, Courtoy PJ, Pierreux CE, Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiation. Dev Biol. 2013 Sep 1;381(1):227-40 |
1* | J:135686 Hirashima M, Sano K, Morisada T, Murakami K, Rossant J, Suda T, Lymphatic vessel assembly is impaired in Aspp1-deficient mouse embryos. Dev Biol. 2008 Apr 1;316(1):149-59 |
1 | J:343095 Honeycutt SE, N'Guetta PY, Hardesty DM, Xiong Y, Cooper SL, Stevenson MJ, O'Brien LL, Netrin 1 directs vascular patterning and maturity in the developing kidney. Development. 2023 Nov 15;150(22) |
1* | J:239792 Hong KY, Bae H, Park I, Park DY, Kim KH, Kubota Y, Cho ES, Kim H, Adams RH, Yoo OJ, Koh GY, Perilipin+ embryonic preadipocytes actively proliferate along growing vasculatures for adipose expansion. Development. 2015 Aug 01;142(15):2623-32 |
1 | J:237341 Houben A, Kostanova-Poliakova D, Weissenbock M, Graf J, Teufel S, von der Mark K, Hartmann C, beta-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis. Development. 2016 Oct 15;143(20):3826-3838 |
2 | J:298082 Hu D, Zhang L, Yang F, Chen F, Li D, Cai CL, Generation of Pecam1 endothelial specific dual reporter mouse model. Genesis. 2020 Sep;58(9):e23384 |
1 | J:321245 Hu S, Mahadevan A, Elysee IF, Choi J, Souchet NR, Bae GH, Taboada AK, Sanketi B, Duhamel GE, Sevier CS, Tao G, Kurpios NA, The asymmetric Pitx2 gene regulates gut muscular-lacteal development and protects against fatty liver disease. Cell Rep. 2021 Nov 23;37(8):110030 |
1 | J:162581 Huillard E, Ziercher L, Blond O, Wong M, Deloulme JC, Souchelnytskyi S, Baudier J, Cochet C, Buchou T, Disruption of CK2beta in embryonic neural stem cells compromises proliferation and oligodendrogenesis in the mouse telencephalon. Mol Cell Biol. 2010 Jun;30(11):2737-49 |
1 | J:122952 Hung IH, Yu K, Lavine KJ, Ornitz DM, FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. Dev Biol. 2007 Jul 15;307(2):300-13 |
1 | J:146619 Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong TT, Shaw RM, Srivastava D, Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell. 2009 Feb;16(2):233-44 |
1 | J:216228 Inoue S, Moriya M, Watanabe Y, Miyagawa-Tomita S, Niihori T, Oba D, Ono M, Kure S, Ogura T, Matsubara Y, Aoki Y, New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome. Hum Mol Genet. 2014 Dec 15;23(24):6553-66 |
1 | J:239364 Ivins S, Chappell J, Vernay B, Suntharalingham J, Martineau A, Mohun TJ, Scambler PJ, The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development. Dev Cell. 2015 May 26;33(4):455-68 |
1 | J:188056 Jameson SA, Lin YT, Capel B, Testis development requires the repression of Wnt4 by Fgf signaling. Dev Biol. 2012 Oct 1;370(1):24-32 |
1 | J:294193 Jones LK, Lam R, McKee KK, Aleksandrova M, Dowling J, Alexander SI, Mallawaarachchi A, Cottle DL, Short KM, Pais L, Miner JH, Mallett AJ, Simons C, McCarthy H, Yurchenco PD, Smyth IM, A mutation affecting laminin alpha 5 polymerisation gives rise to a syndromic developmental disorder. Development. 2020 Jun 22;147(21):dev189183 |
1 | J:190719 Joza S, Wang J, Fox E, Hillman V, Ackerley C, Post M, Loss of semaphorin-neuropilin-1 signaling causes dysmorphic vascularization reminiscent of alveolar capillary dysplasia. Am J Pathol. 2012 Dec;181(6):2003-17 |
1 | J:294228 Kalailingam P, Wang KQ, Toh XR, Nguyen TQ, Chandrakanthan M, Hasan Z, Habib C, Schif A, Radio FC, Dallapiccola B, Weiss K, Nguyen LN, Deficiency of MFSD7c results in microcephaly-associated vasculopathy in Fowler syndrome. J Clin Invest. 2020 Aug 3;130(8):4081-4093 |
1 | J:173649 Kanady JD, Dellinger MT, Munger SJ, Witte MH, Simon AM, Connexin37 and Connexin43 deficiencies in mice disrupt lymphatic valve development and result in lymphatic disorders including lymphedema and chylothorax. Dev Biol. 2011 Jun 15;354(2):253-66 |
1 | J:131554 Kang J, Gu Y, Li P, Johnson BL, Sucov HM, Thomas PS, PDGF-A as an epicardial mitogen during heart development. Dev Dyn. 2008 Mar;237(3):692-701 |
1 | J:239279 Kidoya H, Naito H, Muramatsu F, Yamakawa D, Jia W, Ikawa M, Sonobe T, Tsuchimochi H, Shirai M, Adams RH, Fukamizu A, Takakura N, APJ Regulates Parallel Alignment of Arteries and Veins in the Skin. Dev Cell. 2015 May 04;33(3):247-59 |
1* | J:122404 Kim KE, Sung HK, Koh GY, Lymphatic development in mouse small intestine. Dev Dyn. 2007 Jul;236(7):2020-5 |
1 | J:155826 King P, Paul A, Laufer E, Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21185-90 |
1 | J:123073 Kruger I, Vollmer M, Simmons DG, Elsasser HP, Philipsen S, Suske G, Sp1/Sp3 compound heterozygous mice are not viable: Impaired erythropoiesis and severe placental defects. Dev Dyn. 2007 Aug;236(8):2235-44 |
1 | J:342552 Kulikauskas MR, Oatley M, Yu T, Liu Z, Matsumura L, Kidder E, Ruter D, Bautch VL, Endothelial cell SMAD6 balances Alk1 function to regulate adherens junctions and hepatic vascular development. Development. 2023 Nov 1;150(21) |
1 | J:240472 Kumar N, Srivillibhuthur M, Joshi S, Walton KD, Zhou A, Faller WJ, Perekatt AO, Sansom OJ, Gumucio DL, Xing J, Bonder EM, Gao N, White E, Verzi MP, A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis. Development. 2016 Oct 15;143(20):3711-3722 |
1 | J:340406 Lai Y, Guo Y, Liao C, Mao C, Liu J, Ren C, Yang W, Luo L, Chen W, Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development. Sci Rep. 2023 Sep 13;13(1):15170 |
1 | J:250555 Langen UH, Pitulescu ME, Kim JM, Enriquez-Gasca R, Sivaraj KK, Kusumbe AP, Singh A, Di Russo J, Bixel MG, Zhou B, Sorokin L, Vaquerizas JM, Adams RH, Cell-matrix signals specify bone endothelial cells during developmental osteogenesis. Nat Cell Biol. 2017 Mar;19(3):189-201 |
1 | J:347708 Lartey NL, van der Ent M, Alonzo R, Chen D, King PD, A temporally-restricted pattern of endothelial cell collagen 4 alpha 1 expression during embryonic development determined with a novel knockin Col4a1-P2A-eGFP mouse line. Genesis. 2024 Feb;62(1):e23539 |
1 | J:257184 Leid J, Carrelha J, Boukarabila H, Epelman S, Jacobsen SE, Lavine KJ, Primitive Embryonic Macrophages are Required for Coronary Development and Maturation. Circ Res. 2016 May 13;118(10):1498-511 |
1 | J:95358 Levinson RS, Batourina E, Choi C, Vorontchikhina M, Kitajewski J, Mendelsohn CL, Foxd1-dependent signals control cellularity in the renal capsule, a structure required for normal renal development. Development. 2005 Feb;132(3):529-39 |
1 | J:200617 Li A, Hardy R, Stoner S, Tuckermann J, Seibel M, Zhou H, Deletion of mesenchymal glucocorticoid receptor attenuates embryonic lung development and abdominal wall closure. PLoS One. 2013;8(5):e63578 |
1 | J:278877 Li Y, Lv Z, He L, Huang X, Zhang S, Zhao H, Pu W, Li Y, Yu W, Zhang L, Liu X, Liu K, Tang J, Tian X, Wang QD, Lui KO, Zhou B, Genetic Tracing Identifies Early Segregation of the Cardiomyocyte and Nonmyocyte Lineages. Circ Res. 2019 Jul 19;125(3):343-355 |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1 | J:319475 Liao C, Lu M, Hong Y, Mao C, Chen J, Ren C, Lin M, Chen W, Osteogenic and angiogenic profiles of the palatal process of the maxilla and the palatal process of the palatine bone. J Anat. 2022 Feb;240(2):385-397 |
2 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
1 | J:332090 Lioux G, Liu X, Temino S, Oxendine M, Ayala E, Ortega S, Kelly RG, Oliver G, Torres M, A Second Heart Field-Derived Vasculogenic Niche Contributes to Cardiac Lymphatics. Dev Cell. 2020 Feb 10;52(3):350-363.e6 |
1 | J:291487 Liu D, Kousa AI, O'Neill KE, Rouse P, Popis M, Farley AM, Tomlinson SR, Ulyanchenko S, Guillemot F, Seymour PA, Jorgensen MC, Serup P, Koch U, Radtke F, Blackburn CC, Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development. Development. 2020 Jun 22;147(12):dev178582 |
1* | J:321931 Liu J, Wu X, Lu Q, Molecular divergence of mammalian astrocyte progenitor cells at early gliogenesis. Development. 2022 Mar 1;149(5):dev199985 |
1 | J:285035 Liu K, Tang M, Jin H, Liu Q, He L, Zhu H, Liu X, Han X, Li Y, Zhang L, Tang J, Pu W, Lv Z, Wang H, Ji H, Zhou B, Triple-cell lineage tracing by a dual reporter on a single allele. J Biol Chem. 2020 Jan 17;295(3):690-700 |
1 | J:266564 Liu K, Yu W, Tang M, Tang J, Liu X, Liu Q, Li Y, He L, Zhang L, Evans SM, Tian X, Lui KO, Zhou B, A dual genetic tracing system identifies diverse and dynamic origins of cardiac valve mesenchyme. Development. 2018 Sep 17;145(18):dev167775 |
1 | J:244674 Liu X, Pasula S, Song H, Tessneer KL, Dong Y, Hahn S, Yago T, Brophy ML, Chang B, Cai X, Wu H, McManus J, Ichise H, Georgescu C, Wren JD, Griffin C, Xia L, Srinivasan RS, Chen H, Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function. Sci Signal. 2014 Oct 14;7(347):ra97 |
1 | J:322701 Liu Y, Chen Q, Jeong HW, Koh BI, Watson EC, Xu C, Stehling M, Zhou B, Adams RH, A specialized bone marrow microenvironment for fetal haematopoiesis. Nat Commun. 2022 Mar 14;13(1):1327 |
1 | J:310382 Liu Z, Vong QP, Liu C, Zheng Y, Borg5 is required for angiogenesis by regulating persistent directional migration of the cardiac microvascular endothelial cells. Mol Biol Cell. 2014 Mar;25(6):841-51 |
1 | J:339241 Liu, K., Intercellular genetic tracing of cardiac endothelium in the developing heart. Dev Cell. 2023 Aug 21;58(16):1502-1512 |
1 | J:315454 Loscertales M, Nicolaou F, Jeanne M, Longoni M, Gould DB, Sun Y, Maalouf FI, Nagy N, Donahoe PK, Type IV collagen drives alveolar epithelial-endothelial association and the morphogenetic movements of septation. BMC Biol. 2016 Jul 13;14:59 |
1 | J:326547 Lu P, Wang P, Wu B, Wang Y, Liu Y, Cheng W, Feng X, Yuan X, Atteya MM, Ferro H, Sugi Y, Rydquist G, Esmaily M, Butcher JT, Chang CP, Lenz J, Zheng D, Zhou B, A SOX17-PDGFB signaling axis regulates aortic root development. Nat Commun. 2022 Jul 13;13(1):4065 |
1 | J:335167 Lu P, Wu B, Wang Y, Russell M, Liu Y, Bernard DJ, Zheng D, Zhou B, Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis. Dev Cell. 2023 Mar 29; |
1 | J:241068 Lucitti JL, Sealock R, Buckley BK, Zhang H, Xiao L, Dudley AC, Faber JE, Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke. Stroke. 2016 Dec;47(12):3022-3031 |
1* | J:231234 Luna RL, Kay VR, Ratsep MT, Khalaj K, Bidarimath M, Peterson N, Carmeliet P, Jin A, Croy BA, Placental growth factor deficiency is associated with impaired cerebral vascular development in mice. Mol Hum Reprod. 2016 Feb;22(2):130-42 |
1 | J:316476 Ma W, Gil HJ, Liu X, Diebold LP, Morgan MA, Oxendine-Burns MJ, Gao P, Chandel NS, Oliver G, Mitochondrial respiration controls the Prox1-Vegfr3 feedback loop during lymphatic endothelial cell fate specification and maintenance. Sci Adv. 2021 Apr;7(18) |
1 | J:233282 Maes C, Araldi E, Haigh K, Khatri R, Van Looveren R, Giaccia AJ, Haigh JJ, Carmeliet G, Schipani E, VEGF-independent cell-autonomous functions of HIF-1alpha regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival. J Bone Miner Res. 2012 Mar;27(3):596-609 |
1 | J:156474 Maes C, Goossens S, Bartunkova S, Drogat B, Coenegrachts L, Stockmans I, Moermans K, Nyabi O, Haigh K, Naessens M, Haenebalcke L, Tuckermann JP, Tjwa M, Carmeliet P, Mandic V, David JP, Behrens A, Nagy A, Carmeliet G, Haigh JJ, Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones. EMBO J. 2010 Jan 20;29(2):424-41 |
1 | J:284120 Mahamud MR, Geng X, Ho YC, Cha B, Kim Y, Ma J, Chen L, Myers G, Camper S, Mustacich D, Witte M, Choi D, Hong YK, Chen H, Varshney G, Engel JD, Wang S, Kim TH, Lim KC, Srinivasan RS, GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126. Development. 2019 Nov 5;146(21):dev184218 |
1 | J:132020 Makita R, Uchijima Y, Nishiyama K, Amano T, Chen Q, Takeuchi T, Mitani A, Nagase T, Yatomi Y, Aburatani H, Nakagawa O, Small EV, Cobo-Stark P, Igarashi P, Murakami M, Tominaga J, Sato T, Asano T, Kurihara Y, Kurihara H, Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ. Am J Physiol Renal Physiol. 2008 Mar;294(3):F542-53 |
1 | J:166573 Martinez-Estrada OM, Lettice LA, Essafi A, Guadix JA, Slight J, Velecela V, Hall E, Reichmann J, Devenney PS, Hohenstein P, Hosen N, Hill RE, Munoz-Chapuli R, Hastie ND, Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin. Nat Genet. 2010 Jan;42(1):89-93 |
1 | J:329978 Maruyama K, Miyagawa-Tomita S, Haneda Y, Kida M, Matsuzaki F, Imanaka-Yoshida K, Kurihara H, The cardiopharyngeal mesoderm contributes to lymphatic vessel development in mouse. Elife. 2022 Oct 5;11:e81515 |
1* | J:278916 Maruyama K, Miyagawa-Tomita S, Mizukami K, Matsuzaki F, Kurihara H, Isl1-expressing non-venous cell lineage contributes to cardiac lymphatic vessel development. Dev Biol. 2019 Aug 15;452(2):134-143 |
2 | J:306872 Maruyama K, Naemura K, Arima Y, Uchijima Y, Nagao H, Yoshihara K, Singh MK, Uemura A, Matsuzaki F, Yoshida Y, Kurihara Y, Miyagawa-Tomita S, Kurihara H, Semaphorin3E-PlexinD1 signaling in coronary artery and lymphatic vessel development with clinical implications in myocardial recovery. iScience. 2021 Apr 23;24(4):102305 |
1 | J:310900 Mesnieres M, Bohm AM, Peredo N, Trompet D, Valle-Tenney R, Bajaj M, Corthout N, Nefyodova E, Cardoen R, Baatsen P, Munck S, Nagy A, Haigh JJ, Khurana S, Verfaillie CM, Maes C, Fetal hematopoietic stem cell homing is controlled by VEGF regulating the integrity and oxidative status of the stromal-vascular bone marrow niches. Cell Rep. 2021 Aug 24;36(8):109618 |
1* | J:59925 Miner JH, Li C, Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane. Dev Biol. 2000 Jan 15;217(2):278-89 |
1 | J:269506 Minocha S, Valloton D, Brunet I, Eichmann A, Hornung JP, Lebrand C, NG2 glia are required for vessel network formation during embryonic development. Elife. 2015 Dec 10;4:e09102 |
1 | J:225118 Mirza M, Pang MF, Zaini MA, Haiko P, Tammela T, Alitalo K, Philipson L, Fuxe J, Sollerbrant K, Essential role of the coxsackie- and adenovirus receptor (CAR) in development of the lymphatic system in mice. PLoS One. 2012;7(5):e37523 |
1* | J:100943 Mirza M, Raschperger E, Philipson L, Pettersson RF, Sollerbrant K, The cell surface protein coxsackie- and adenovirus receptor (CAR) directly associates with the Ligand-of-Numb Protein-X2 (LNX2). Exp Cell Res. 2005 Sep 10;309(1):110-20 |
1 | J:236002 Miura S, Kondo J, Takimoto A, Sano-Takai H, Guo L, Shukunami C, Tanaka H, Hiraki Y, The N-terminal cleavage of chondromodulin-I in growth-plate cartilage at the hypertrophic and calcified zones during bone development. PLoS One. 2014;9(4):e94239 |
1 | J:341495 Mizukoshi T, Yamada S, Sakakibara SI, Spatiotemporal Regulation of De Novo and Salvage Purine Synthesis during Brain Development. eNeuro. 2023 Oct;10(10):ENEURO.0159-23.2023 |
1 | J:318774 Monemdjou R, Vasheghani F, Fahmi H, Perez G, Blati M, Taniguchi N, Lotz M, St-Arnaud R, Pelletier JP, Martel-Pelletier J, Beier F, Kapoor M, Association of cartilage-specific deletion of peroxisome proliferator-activated receptor gamma with abnormal endochondral ossification and impaired cartilage growth and development in a murine model. Arthritis Rheum. 2012 May;64(5):1551-61 |
1 | J:262023 Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K, Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling. Circ Res. 2017 Apr 14;120(8):1276-1288 |
2 | J:288301 Mu Y, Yu H, Wu T, Zhang J, Evans SM, Chen J, O-linked beta-N-acetylglucosamine transferase plays an essential role in heart development through regulating angiopoietin-1. PLoS Genet. 2020 Apr;16(4):e1008730 |
1 | J:231667 Munger SJ, Geng X, Srinivasan RS, Witte MH, Paul DL, Simon AM, Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice. Dev Biol. 2016 Apr 15;412(2):173-90 |
1 | J:275137 Munro DAD, Wineberg Y, Tarnick J, Vink CS, Li Z, Pridans C, Dzierzak E, Kalisky T, Hohenstein P, Davies JA, Macrophages restrict the nephrogenic field and promote endothelial connections during kidney development. Elife. 2019 Feb 13;8:e43271 |
2* | J:77927 Muto S, Aiba A, Saito Y, Nakao K, Nakamura K, Tomita K, Kitamura T, Kurabayashi M, Nagai R, Higashihara E, Harris PC, Katsuki M, Horie S, Pioglitazone improves the phenotype and molecular defects of a targeted Pkd1 mutant. Hum Mol Genet. 2002 Jul 15;11(15):1731-42 |
1 | J:358157 N'Guetta PY, McLarnon SR, Tassou A, Geron M, Shirvan S, Hill RZ, Scherrer G, O'Brien LL, Comprehensive mapping of sensory and sympathetic innervation of the developing kidney. Cell Rep. 2024 Oct 22;43(10):114860 |
1 | J:194919 Nam J, Onitsuka I, Hatch J, Uchida Y, Ray S, Huang S, Li W, Zang H, Ruiz-Lozano P, Mukouyama YS, Coronary veins determine the pattern of sympathetic innervation in the developing heart. Development. 2013 Apr;140(7):1475-85 |
1 | J:77264 Nguyen NM, Miner JH, Pierce RA, Senior RM, Laminin alpha 5 is required for lobar septation and visceral pleural basement membrane formation in the developing mouse lung. Dev Biol. 2002 Jun 15;246(2):231-44 |
1 | J:163740 Ni A, Lashnits E, Yao LC, Baluk P, McDonald DM, Rapid remodeling of airway vascular architecture at birth. Dev Dyn. 2010 Sep;239(9):2354-66 |
1 | J:191589 Nishimura R, Wakabayashi M, Hata K, Matsubara T, Honma S, Wakisaka S, Kiyonari H, Shioi G, Yamaguchi A, Tsumaki N, Akiyama H, Yoneda T, Osterix regulates calcification and degradation of chondrogenic matrices through matrix metalloproteinase 13 (MMP13) expression in association with transcription factor Runx2 during endochondral ossification. J Biol Chem. 2012 Sep 28;287(40):33179-90 |
1 | J:295953 Niu X, Liu L, Wang T, Chuan X, Yu Q, Du M, Gu Y, Wang L, Mapping of Extrinsic Innervation of the Gastrointestinal Tract in the Mouse Embryo. J Neurosci. 2020 Aug 26;40(35):6691-6708 |
1 | J:275825 Norman TA Jr, Gower AC, Chen F, Fine A, Transcriptional landscape of pulmonary lymphatic endothelial cells during fetal gestation. PLoS One. 2019;14(5):e0216795 |
1 | J:181485 Oh JH, Park SY, de Crombrugghe B, Kim JE, Chondrocyte-specific ablation of Osterix leads to impaired endochondral ossification. Biochem Biophys Res Commun. 2012 Feb 24;418(4):634-40 |
1 | J:207212 Oh WJ, Gu C, Establishment of neurovascular congruency in the mouse whisker system by an independent patterning mechanism. Neuron. 2013 Oct 16;80(2):458-69 |
1 | J:361601 Park CJ, Oh JE, Lin P, Zhou S, Bunnell M, Bikorimana E, Spinella MJ, Lim HJ, Ko CJ, A Dynamic Shift in Estrogen Receptor Expression During Granulosa Cell Differentiation in the Ovary. Endocrinology. 2025 Jan 6;166(2) |
1 | J:258274 Patra D, DeLassus E, Mueller J, Abou-Ezzi G, Sandell LJ, Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice. Biol Open. 2018 Feb 22;7(2):bio032094 |
1 | J:266206 Peterson JC, Chughtai M, Wisse LJ, Gittenberger-de Groot AC, Feng Q, Goumans MTH, VanMunsteren JC, Jongbloed MRM, DeRuiter MC, Nos3 mutation leads to abnormal neural crest cell and second heart field lineage patterning in bicuspid aortic valve formation. Dis Model Mech. 2018 Sep 20;:dmm034637 |
1 | J:221833 Prakash A, Udager AM, Saenz DA, Gumucio DL, Roles for Nkx2-5 and Gata3 in the ontogeny of the murine smooth muscle gastric ligaments. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 15;307(4):G430-6 |
1 | J:140378 Qu X, Lam E, Doughman YQ, Chen Y, Chou YT, Lam M, Turakhia M, Dunwoodie SL, Watanabe M, Xu B, Duncan SA, Yang YC, Cited2, a coactivator of HNF4alpha, is essential for liver development. EMBO J. 2007 Oct 31;26(21):4445-56 |
1 | J:158668 Qu X, Tompkins K, Batts LE, Puri M, Baldwin S, Abnormal embryonic lymphatic vessel development in Tie1 hypomorphic mice. Development. 2010 Apr;137(8):1285-95 |
2 | J:281274 Qu X, Violette K, Sewell-Loftin MK, Soslow J, Saint-Jean L, Hinton RB, Merryman WD, Baldwin HS, Loss of flow responsive Tie1 results in ImpairedAortic valve remodeling. Dev Biol. 2019 Nov 1;455(1):73-84 |
1 | J:239420 Rantakari P, Jappinen N, Lokka E, Mokkala E, Gerke H, Peuhu E, Ivaska J, Elima K, Auvinen K, Salmi M, Fetal liver endothelium regulates the seeding of tissue-resident macrophages. Nature. 2016 Oct 20;538(7625):392-396 |
1 | J:208409 Reinert RB, Cai Q, Hong JY, Plank JL, Aamodt K, Prasad N, Aramandla R, Dai C, Levy SE, Pozzi A, Labosky PA, Wright CV, Brissova M, Powers AC, Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding. Development. 2014 Apr;141(7):1480-91 |
1 | J:292237 Roostalu U, Aldeiri B, Albertini A, Humphreys N, Simonsen-Jackson M, Wong JKF, Cossu G, Distinct Cellular Mechanisms Underlie Smooth Muscle Turnover in Vascular Development and Repair. Circ Res. 2018 Jan 19;122(2):267-281 |
1 | J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088 |
1 | J:170315 Rothova M, Feng J, Sharpe PT, Peterkova R, Tucker AS, Contribution of mesoderm to the developing dental papilla. Int J Dev Biol. 2011;55(1):59-64 |
1 | J:249238 Roukens MG, Peterson-Maduro J, Padberg Y, Jeltsch M, Leppanen VM, Bos FL, Alitalo K, Schulte-Merker S, Schulte D, Functional Dissection of the CCBE1 Protein: A Crucial Requirement for the Collagen Repeat Domain. Circ Res. 2015 May 8;116(10):1660-9 |
1 | J:126927 Ruiz-Ederra J, Verkman AS, Aquaporin-1 independent microvessel proliferation in a neonatal mouse model of oxygen-induced retinopathy. Invest Ophthalmol Vis Sci. 2007 Oct;48(10):4802-10 |
1 | J:181330 Sabine A, Agalarov Y, Maby-El Hajjami H, Jaquet M, Hagerling R, Pollmann C, Bebber D, Pfenniger A, Miura N, Dormond O, Calmes JM, Adams RH, Makinen T, Kiefer F, Kwak BR, Petrova TV, Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation. Dev Cell. 2012 Feb 14;22(2):430-45 |
2 | J:361603 Scavuzzo MA, Szlachcic WJ, Hill MC, Ziojla NM, Teaw J, Carlson JC, Tiessen J, Chmielowiec J, Martin JF, Borowiak M, Pancreatic organogenesis mapped through space and time. Exp Mol Med. 2025 Feb;57(1):204-220 |
1 | J:181230 Scotti M, Kmita M, Recruitment of 5' Hoxa genes in the allantois is essential for proper extra-embryonic function in placental mammals. Development. 2012 Feb;139(4):731-9 |
1 | J:346597 Seo S, Sonn SK, Kweon HY, Jin J, Kume T, Ko JY, Park JH, Oh GT, Primary Cilium in Neural Crest Cells Crucial for Anterior Segment Development and Corneal Avascularity. Invest Ophthalmol Vis Sci. 2024 Mar 5;65(3):30 |
1* | J:145448 Shimoda H, Immunohistochemical demonstration of Angiopoietin-2 in lymphatic vascular development. Histochem Cell Biol. 2009 Feb;131(2):231-8 |
1 | J:135068 Shukunami C, Takimoto A, Miura S, Nishizaki Y, Hiraki Y, Chondromodulin-I and tenomodulin are differentially expressed in the avascular mesenchyme during mouse and chick development. Cell Tissue Res. 2008 Apr;332(1):111-22 |
1 | J:187998 Shung CY, Ota S, Zhou ZQ, Keene DR, Hurlin PJ, Disruption of a Sox9-beta-catenin circuit by mutant Fgfr3 in thanatophoric dysplasia type II. Hum Mol Genet. 2012 Nov 1;21(21):4628-44 |
1 | J:177488 Srinivasan RS, Oliver G, Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves. Genes Dev. 2011 Oct 15;25(20):2187-97 |
1 | J:231970 Stevens SM, Gise Av, VanDusen N, Zhou B, Pu WT, Epicardium is required for cardiac seeding by yolk sac macrophages, precursors of resident macrophages of the adult heart. Dev Biol. 2016 May 15;413(2):153-9 |
1 | J:84301 Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M, The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 2003 Jul 1;17(13):1677-89 |
1 | J:260094 Stremmel C, Schuchert R, Wagner F, Thaler R, Weinberger T, Pick R, Mass E, Ishikawa-Ankerhold HC, Margraf A, Hutter S, Vagnozzi R, Klapproth S, Frampton J, Yona S, Scheiermann C, Molkentin JD, Jeschke U, Moser M, Sperandio M, Massberg S, Geissmann F, Schulz C, Yolk sac macrophage progenitors traffic to the embryo during defined stages of development. Nat Commun. 2018 Jan 8;9(1):75 |
1 | J:239521 Stzepourginski I, Nigro G, Jacob JM, Dulauroy S, Sansonetti PJ, Eberl G, Peduto L, CD34+ mesenchymal cells are a major component of the intestinal stem cells niche at homeostasis and after injury. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E506-E513 |
1 | J:227907 Sultana N, Zhang L, Yan J, Chen J, Cai W, Razzaque S, Jeong D, Sheng W, Bu L, Xu M, Huang GY, Hajjar RJ, Zhou B, Moon A, Cai CL, Resident c-kit(+) cells in the heart are not cardiac stem cells. Nat Commun. 2015;6:8701 |
1 | J:319547 Taib S, Lamande N, Martin S, Coulpier F, Topilko P, Brunet I, Myelinating Schwann cells and Netrin-1 control intra-nervous vascularization of the developing mouse sciatic nerve. Elife. 2022 Jan 12;11:e64773 |
1 | J:247344 Takahashi K, Kim R, Lauhan C, Park Y, Nguyen NG, Vestweber D, Dominguez MG, Valenzuela DM, Murphy AJ, Yancopoulos GD, Gale NW, Takahashi T, Expression of receptor-type protein tyrosine phosphatase in developing and adult renal vasculature. PLoS One. 2017;12(5):e0177192 |
1 | J:221216 Takashima Y, Terada M, Kawabata M, Suzuki A, Dynamic three-dimensional morphogenesis of intrahepatic bile ducts in mouse liver development. Hepatology. 2015 Mar;61(3):1003-11 |
1 | J:222261 Tan KS, Inoue T, Kulkeaw K, Tanaka Y, Lai MI, Sugiyama D, Localized SCF and IGF-1 secretion enhances erythropoiesis in the spleen of murine embryos. Biol Open. 2015;4(5):596-607 |
1* | J:136802 Tang H, Ross A, Capel B, Expression and functional analysis of Gm114, a putative mammalian ortholog of Drosophila bam. Dev Biol. 2008 Jun 1;318(1):73-81 |
1 | J:125052 Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H, Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification. Mol Cell Biol. 2007 Aug;27(16):5650-63 |
1 | J:272733 Thomson BR, Souma T, Tompson SW, Onay T, Kizhatil K, Siggs OM, Feng L, Whisenhunt KN, Yanovitch TL, Kalaydjieva L, Azmanov DN, Finzi S, Tanna CE, Hewitt AW, Mackey DA, Bradfield YS, Souzeau E, Javadiyan S, Wiggs JL, Pasutto F, Liu X, John SW, Craig JE, Jin J, Young TL, Quaggin SE, Angiopoietin-1 is required for Schlemm's canal development in mice and humans. J Clin Invest. 2017 Dec 1;127(12):4421-4436 |
1 | J:299728 Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL, Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. Elife. 2019 Dec 4;8:e49977 |
1 | J:175540 Tsau C, Ito M, Gromova A, Hoffman MP, Meech R, Makarenkova HP, Barx2 and Fgf10 regulate ocular glands branching morphogenesis by controlling extracellular matrix remodeling. Development. 2011 Aug;138(15):3307-17 |
1 | J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521 |
1* | J:80128 van der Zwaag B, Hellemons AJ, Leenders WP, Burbach JP, Brunner HG, Padberg GW, Van Bokhoven H, PLEXIN-D1, a novel plexin family member, is expressed in vascular endothelium and the central nervous system during mouse embryogenesis. Dev Dyn. 2002 Nov;225(3):336-43 |
2 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1* | J:84143 Wakayama T, Hamada K, Yamamoto M, Suda T, Iseki S, The expression of platelet endothelial cell adhesion molecule-1 in mouse primordial germ cells during their migration and early gonadal formation. Histochem Cell Biol. 2003 May;119(5):355-62 |
1 | J:122563 Wang G, Woods A, Agoston H, Ulici V, Glogauer M, Beier F, Genetic ablation of Rac1 in cartilage results in chondrodysplasia. Dev Biol. 2007 Jun 15;306(2):612-23 |
1 | J:238547 Wang X, Chen D, Chen K, Jubran A, Ramirez A, Astrof S, Endothelium in the pharyngeal arches 3, 4 and 6 is derived from the second heart field. Dev Biol. 2017 Jan 15;421(2):108-117 |
1 | J:233746 Wang X, Wang Y, Snitow ME, Stewart KM, Li S, Lu M, Morrisey EE, Expression of histone deacetylase 3 instructs alveolar type I cell differentiation by regulating a Wnt signaling niche in the lung. Dev Biol. 2016 Jun 15;414(2):161-9 |
1 | J:261826 Wang Y, Wu B, Farrar E, Lui W, Lu P, Zhang D, Alfieri CM, Mao K, Chu M, Yang D, Xu D, Rauchman M, Taylor V, Conway SJ, Yutzey KE, Butcher JT, Zhou B, Notch-Tnf signalling is required for development and homeostasis of arterial valves. Eur Heart J. 2017 Mar 1;38(9):675-686 |
3 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1* | J:158680 Wansleeben C, Feitsma H, Montcouquiol M, Kroon C, Cuppen E, Meijlink F, Planar cell polarity defects and defective Vangl2 trafficking in mutants for the COPII gene Sec24b. Development. 2010 Apr;137(7):1067-73 |
1 | J:147206 Warr N, Siggers P, Bogani D, Brixey R, Pastorelli L, Yates L, Dean CH, Wells S, Satoh W, Shimono A, Greenfield A, Sfrp1 and Sfrp2 are required for normal male sexual development in mice. Dev Biol. 2009 Feb 15;326(2):273-84 |
1 | J:236410 Watson EC, Koenig MN, Grant ZL, Whitehead L, Trounson E, Dewson G, Coultas L, Apoptosis regulates endothelial cell number and capillary vessel diameter but not vessel regression during retinal angiogenesis. Development. 2016 Aug 15;143(16):2973-82 |
1 | J:102947 Wilm B, Ipenberg A, Hastie ND, Burch JB, Bader DM, The serosal mesothelium is a major source of smooth muscle cells of the gut vasculature. Development. 2005 Dec;132(23):5317-28 |
1* | J:203805 Wu SP, Dong XR, Regan JN, Su C, Majesky MW, Tbx18 regulates development of the epicardium and coronary vessels. Dev Biol. 2013 Nov 15;383(2):307-20 |
1 | J:202407 Xiao Y, Woo WM, Nagao K, Li W, Terunuma A, Mukouyama YS, Oro AE, Vogel JC, Brownell I, Perivascular hair follicle stem cells associate with a venule annulus. J Invest Dermatol. 2013 Oct;133(10):2324-31 |
1* | J:146829 Yamada W, Nagao K, Horikoshi K, Fujikura A, Ikeda E, Inagaki Y, Kakitani M, Tomizuka K, Miyazaki H, Suda T, Takubo K, Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun. 2009 Apr 10;381(3):453-8 |
1 | J:278463 Yang Y, Cha B, Motawe ZY, Srinivasan RS, Scallan JP, VE-Cadherin Is Required for Lymphatic Valve Formation and Maintenance. Cell Rep. 2019;28(9):2397-2412 |
1* | J:90277 Yao HH, Matzuk MM, Jorgez CJ, Menke DB, Page DC, Swain A, Capel B, Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis. Dev Dyn. 2004 Jun;230(2):210-5 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
1* | J:165724 Yu S, Poe B, Schwarz M, Elliot SA, Albertine KH, Fenton S, Garg V, Moon AM, Fetal and postnatal lung defects reveal a novel and required role for Fgf8 in lung development. Dev Biol. 2010 Nov 1;347(1):92-108 |
1* | J:75934 Zelzer E, McLean W, Ng YS, Fukai N, Reginato AM, Lovejoy S, D'Amore PA, Olsen BR, Skeletal defects in VEGF(120/120) mice reveal multiple roles for VEGF in skeletogenesis. Development. 2002 Apr;129(8):1893-904 |
2 | J:208012 Zhang B, Xiao W, Qiu H, Zhang F, Moniz HA, Jaworski A, Condac E, Gutierrez-Sanchez G, Heiss C, Clugston RD, Azadi P, Greer JJ, Bergmann C, Moremen KW, Li D, Linhardt RJ, Esko JD, Wang L, Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia. J Clin Invest. 2014 Jan 2;124(1):209-21 |
1* | J:171387 Zhang H, Tse J, Hu X, Witte M, Bernas M, Kang J, Tilahun F, Hong YK, Qiu M, Chen L, Novel discovery of LYVE-1 expression in the hyaloid vascular system. Invest Ophthalmol Vis Sci. 2010 Dec;51(12):6157-61 |
1* | J:68672 Zhao J, Chen H, Peschon JJ, Shi W, Zhang Y, Frank SJ, Warburton D, Pulmonary hypoplasia in mice lacking tumor necrosis factor-alpha converting enzyme indicates an indispensable role for cell surface protein shedding during embryonic lung branching morphogenesis. Dev Biol. 2001 Apr 1;232(1):204-18 |
1 | J:196696 Zou Z, Enis DR, Bui H, Khandros E, Kumar V, Jakus Z, Thom C, Yang Y, Dhillon V, Chen M, Lu M, Weiss MJ, Kahn ML, The secreted lymphangiogenic factor CCBE1 is essential for fetal liver erythropoiesis. Blood. 2013 Apr 18;121(16):3228-36 |
1 | J:157920 Zovein AC, Luque A, Turlo KA, Hofmann JJ, Yee KM, Becker MS, Fassler R, Mellman I, Lane TF, Iruela-Arispe ML, Beta1 integrin establishes endothelial cell polarity and arteriolar lumen formation via a Par3-dependent mechanism. Dev Cell. 2010 Jan 19;18(1):39-51 |
Peg3 paternally expressed 3 (Synonyms: End4, Gcap4, Pw1, Zfp102) | |
Results | Reference |
1 | J:72872 Bain G, Mansergh FC, Wride MA, Hance JE, Isogawa A, Rancourt SL, Ray WJ, Yoshimura Y, Tsuzuki T, Gottlieb DI, Rancourt DE, ES cell neural differentiation reveals a substantial number of novel ESTs. Funct Integr Genomics. 2000 Sep;1(2):127-139 |
1 | J:232551 Denizot AL, Besson V, Correra RM, Mazzola A, Lopes I, Courbard JR, Marazzi G, Sassoon DA, A Novel Mutant Allele of Pw1/Peg3 Does Not Affect Maternal Behavior or Nursing Behavior. PLoS Genet. 2016 May;12(5):e1006053 |
1 | J:218430 Kamimura S, Hatanaka Y, Hirasawa R, Matsumoto K, Oikawa M, Lee J, Matoba S, Mizutani E, Ogonuki N, Inoue K, Kohda T, Ishino F, Ogura A, Establishment of paternal genomic imprinting in mouse prospermatogonia analyzed by nuclear transfer. Biol Reprod. 2014 Nov;91(5):120 |
1* | J:267655 Marjonen H, Toivonen M, Lahti L, Kaminen-Ahola N, Early prenatal alcohol exposure alters imprinted gene expression in placenta and embryo in a mouse model. PLoS One. 2018;13(5):e0197461 |
Peg10 paternally expressed 10 (Synonyms: Edr, HB-1, Mar2, Mart2, MEF3L, MyEF-3, MyEF-3 like, Rtl2) | |
Results | Reference |
1 | J:72112 Shigemoto K, Brennan J, Walls E, Watson CJ, Stott D, Rigby PW, Reith AD, Identification and characterisation of a developmentally regulated mammalian gene that utilises -1 programmed ribosomal frameshifting. Nucleic Acids Res. 2001 Oct 1;29(19):4079-88 |
Pelo pelota mRNA surveillance and ribosome rescue factor | |
Results | Reference |
1 | J:306384 Terrey M, Adamson SI, Chuang JH, Ackerman SL, Defects in translation-dependent quality control pathways lead to convergent molecular and neurodevelopmental pathology. Elife. 2021 Apr 26;10:e66904 |
Penk preproenkephalin (Synonyms: ENK, Penk, Penk1, PPA) | |
Results | Reference |
1 | J:119559 Bouwman J, Spijker S, Schut D, Wachtler B, Ylstra B, Smit AB, Verhage M, Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse. J Neurochem. 2006 Oct;99(1):84-96 |
1 | J:178178 Bupesh M, Abellan A, Medina L, Genetic and experimental evidence supports the continuum of the central extended amygdala and a mutiple embryonic origin of its principal neurons. J Comp Neurol. 2011 Dec 1;519(17):3507-31 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:142008 Huang M, Huang T, Xiang Y, Xie Z, Chen Y, Yan R, Xu J, Cheng L, Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons. Dev Biol. 2008 Jul 2;322(2):394-405 |
1 | J:244498 Lee B, Lee M, Song S, Loi LD, Lam DT, Yoon J, Baek K, Curtis DJ, Jeong Y, Specification of neurotransmitter identity by Tal1 in thalamic nuclei. Dev Dyn. 2017 Oct;246(10):749-758 |
1 | J:361228 Li Z, Shang Z, Sun M, Jiang X, Tian Y, Yang L, Wang Z, Su Z, Liu G, Li X, You Y, Yang Z, Xu Z, Zhang Z, Transcription factor Sp9 is a negative regulator of D1-type MSN development. Cell Death Discov. 2022 Jun 30;8(1):301 |
1* | J:221341 Lun MP, Johnson MB, Broadbelt KG, Watanabe M, Kang YJ, Chau KF, Springel MW, Malesz A, Sousa AM, Pletikos M, Adelita T, Calicchio ML, Zhang Y, Holtzman MJ, Lidov HG, Sestan N, Steen H, Monuki ES, Lehtinen MK, Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production. J Neurosci. 2015 Mar 25;35(12):4903-16 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1* | J:41496 Vitale M, Vashishtha A, Linzer E, Powell DJ, Friedman JM, Molecular cloning of the mouse CCK gene: expression in different brain regions and during cortical development. Nucleic Acids Res. 1991 Jan 11;19(1):169-77 |
1 | J:319016 Yan R, Huang T, Xie Z, Xia G, Qian H, Zhao X, Cheng L, Lmx1b controls peptide phenotypes in serotonergic and dopaminergic neurons. Acta Biochim Biophys Sin (Shanghai). 2013 May;45(5):345-52 |
2 | J:238868 Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z, The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 2016 Aug 02;16(5):1431-44 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
Per1 period circadian clock 1 (Synonyms: Hftm, mPer1, m-rigui) | |
Results | Reference |
2* | J:325107 Cao X, Yan Y, Luo X, Yang X, Cui H, Yang Y, Li H, Analyses of the circadian clock genes expression in whole embryos and maternal major tissues of mice. J Mol Histol. 2022 Apr;53(2):473-482 |
1* | J:161413 Ratajczak CK, Herzog ED, Muglia LJ, Clock gene expression in gravid uterus and extra-embryonic tissues during late gestation in the mouse. Reprod Fertil Dev. 2010;22(5):743-50 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
2 | J:329949 Yuan H, Xie B, Yu X, Lin C, Li M, Zhang Y, Zou X, Lu M, Zhao M, Wen X, A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development. Front Physiol. 2022;13:981311 |
Per2 period circadian clock 2 (Synonyms: mKIAA0347, mPer2) | |
Results | Reference |
1* | J:158725 Dolatshad H, Cary AJ, Davis FC, Differential expression of the circadian clock in maternal and embryonic tissues of mice. PLoS One. 2010;5(3):e9855 |
1* | J:161413 Ratajczak CK, Herzog ED, Muglia LJ, Clock gene expression in gravid uterus and extra-embryonic tissues during late gestation in the mouse. Reprod Fertil Dev. 2010;22(5):743-50 |
1 | J:329949 Yuan H, Xie B, Yu X, Lin C, Li M, Zhang Y, Zou X, Lu M, Zhao M, Wen X, A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development. Front Physiol. 2022;13:981311 |
Per3 period circadian clock 3 (Synonyms: 2810049O06Rik, mPer3) | |
Results | Reference |
1* | J:278635 Noda M, Iwamoto I, Tabata H, Yamagata T, Ito H, Nagata KI, Role of Per3, a circadian clock gene, in embryonic development of mouse cerebral cortex. Sci Rep. 2019 Apr 10;9(1):5874 |
Perp PERP, TP53 apoptosis effector (Synonyms: 1110017A08Rik, KCP1, KRTCAP1, PIGPC1) | |
Results | Reference |
1* | J:97304 Ihrie RA, Marques MR, Nguyen BT, Horner JS, Papazoglu C, Bronson RT, Mills AA, Attardi LD, Perp is a p63-regulated gene essential for epithelial integrity. Cell. 2005 Mar 25;120(6):843-56 |
1 | J:182873 Jheon AH, Mostowfi P, Snead ML, Ihrie RA, Sone E, Pramparo T, Attardi LD, Klein OD, PERP regulates enamel formation via effects on cell-cell adhesion and gene expression. J Cell Sci. 2011 Mar 1;124(Pt 5):745-54 |
2* | J:293448 Neupane S, Sohn WJ, Rijal G, Lee YJ, Lee S, Yamamoto H, An CH, Cho SW, Lee Y, Shin HI, Kwon TY, Kim JY, Developmental regulations of Perp in mice molar morphogenesis. Cell Tissue Res. 2014 Oct;358(1):109-21 |
Pex13 peroxisomal biogenesis factor 13 (Synonyms: 2610008O20Rik) | |
Results | Reference |
1* | J:224930 Cheerathodi M, Vincent JJ, Ballif BA, Quantitative comparison of CrkL-SH3 binding proteins from embryonic murine brain and liver: Implications for developmental signaling and the quantification of protein species variants in bottom-up proteomics. J Proteomics. 2015 Jul 1;125:104-11 |
Pf4 platelet factor 4 (Synonyms: Cxcl4, Pf4, Scyb4) | |
Results | Reference |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
Pfas phosphoribosylformylglycinamidine synthase (FGAR amidotransferase) (Synonyms: 4432409B16Rik, Sofa) | |
Results | Reference |
1 | J:341495 Mizukoshi T, Yamada S, Sakakibara SI, Spatiotemporal Regulation of De Novo and Salvage Purine Synthesis during Brain Development. eNeuro. 2023 Oct;10(10):ENEURO.0159-23.2023 |
Pfkfb3 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (Synonyms: E330010H22Rik, uPFK-2) | |
Results | Reference |
1* | J:314146 Gao W, Zhang Y, Luo H, Niu M, Zheng X, Hu W, Cui J, Xue X, Bo Y, Dai F, Lu Y, Yang D, Guo Y, Guo H, Li H, Zhang Y, Yang T, Li L, Zhang L, Hou R, Wen S, An C, Ma T, Jin L, Xu W, Wu Y, Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis. Cell Death Dis. 2020 Oct 26;11(10):919 |
Pfn2 profilin 2 (Synonyms: Pfn) | |
Results | Reference |
1* | J:244564 Lin Q, Ponnusamy R, Widagdo J, Choi JA, Ge W, Probst C, Buckley T, Lou M, Bredy TW, Fanselow MS, Ye K, Sun YE, MicroRNA-mediated disruption of dendritogenesis during a critical period of development influences cognitive capacity later in life. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9188-9193 |
Pga5 pepsinogen 5, group I (Synonyms: 1110035E17Rik, Pepf, pepsinogen A5) | |
Results | Reference |
3* | J:71953 Chen X, Rosenfeld CS, Roberts RM, Green JA, An aspartic proteinase expressed in the yolk sac and neonatal stomach of the mouse. Biol Reprod. 2001 Oct;65(4):1092-101 |
Pgap2 post-GPI attachment to proteins 2 (Synonyms: 1810006G21Rik, clpex, Frag1) | |
Results | Reference |
1* | J:277316 Lukacs M, Roberts T, Chatuverdi P, Stottmann RW, Glycosylphosphatidylinositol biosynthesis and remodeling are required for neural tube closure, heart development, and cranial neural crest cell survival. Elife. 2019 Jun 24;8:e45248 |
Pgc progastricsin (pepsinogen C) (Synonyms: 2210410L06Rik, Upg-1, Upg1) | |
Results | Reference |
2 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
Pgf placental growth factor (Synonyms: PIGF, placenta growth factor, PLGF) | |
Results | Reference |
1 | J:311143 Courtney JA, Wilson RL, Cnota J, Jones HN, Conditional Mutation of Hand1 in the Mouse Placenta Disrupts Placental Vascular Development Resulting in Fetal Loss in Both Early and Late Pregnancy. Int J Mol Sci. 2021 Sep 2;22(17) |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
2* | J:231234 Luna RL, Kay VR, Ratsep MT, Khalaj K, Bidarimath M, Peterson N, Carmeliet P, Jin A, Croy BA, Placental growth factor deficiency is associated with impaired cerebral vascular development in mice. Mol Hum Reprod. 2016 Feb;22(2):130-42 |
1* | J:74493 Maes C, Carmeliet P, Moermans K, Stockmans I, Smets N, Collen D, Bouillon R, Carmeliet G, Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF(164) and VEGF(188). Mech Dev. 2002 Feb;111(1-2):61-73 |
Pgk1 phosphoglycerate kinase 1 (Synonyms: Pgk-1) | |
Results | Reference |
1* | J:78912 Hellstrom M, Gerhardt H, Kalen M, Li X, Eriksson U, Wolburg H, Betsholtz C, Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol. 2001 Apr 30;153(3):543-53 |
1* | J:134647 Honda JY, Kobayashi I, Kiyoshima T, Yamaza H, Xie M, Takahashi K, Enoki N, Nagata K, Nakashima A, Sakai H, Glycolytic enzyme Pgk1 is strongly expressed in the developing tooth germ of the mouse lower first molar. Histol Histopathol. 2008 Apr;23(4):423-32 |
1 | J:233282 Maes C, Araldi E, Haigh K, Khatri R, Van Looveren R, Giaccia AJ, Haigh JJ, Carmeliet G, Schipani E, VEGF-independent cell-autonomous functions of HIF-1alpha regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival. J Bone Miner Res. 2012 Mar;27(3):596-609 |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
Pgm1 phosphoglucomutase 1 (Synonyms: 2610020G18Rik, Pgm1a, Pgm-2, Pgm2) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
Pgm2 phosphoglucomutase 2 (Synonyms: 3230402E02Rik, Pgm-1, Pgm1) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
Pgm3 phosphoglucomutase 3 (Synonyms: 2810473H05Rik, GlcNAc-P mutase, Pgm-3) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
Pgr progesterone receptor (Synonyms: 9930019P03Rik, ENSMUSG00000074510, NR3C3, PR, PR-A, PR-B) | |
Results | Reference |
1* | J:85725 Beyer C, Kuppers E, Karolczak M, Trotter A, Ontogenetic expression of estrogen and progesterone receptors in the mouse lung. Biol Neonate. 2003;84(1):59-63 |
Phactr1 phosphatase and actin regulator 1 (Synonyms: 9630030F18Rik, Rpel1) | |
Results | Reference |
1 | J:261960 Ito H, Mizuno M, Noguchi K, Morishita R, Iwamoto I, Hara A, Nagata KI, Expression analyses of Phactr1 (phosphatase and actin regulator 1) during mouse brain development. Neurosci Res. 2018 Mar;128:50-57 |
Phactr4 phosphatase and actin regulator 4 (Synonyms: 3110001B12Rik, C330013F19Rik) | |
Results | Reference |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
Phc1 polyhomeotic 1 (Synonyms: Edr1, Mph1, rae28, Rae-28) | |
Results | Reference |
2* | J:38105 Alkema MJ, Bronk M, Verhoeven E, Otte A, van't Veer LJ, Berns A, van Lohuizen M, Identification of Bmi1-interacting proteins as constituents of a multimeric mammalian polycomb complex. Genes Dev. 1997 Jan 15;11(2):226-40 |
1* | J:47794 Hashimoto N, Brock HW, Nomura M, Kyba M, Hodgson J, Fujita Y, Takihara Y, Shimada K, Higashinakagawa T, RAE28, BMI1, and M33 are members of heterogeneous multimeric mammalian Polycomb group complexes. Biochem Biophys Res Commun. 1998 Apr 17;245(2):356-65 |
Phex phosphate regulating endopeptidase homolog, X-linked (Synonyms: HPDR1) | |
Results | Reference |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
1* | J:307192 Yadav PS, Feng S, Cong Q, Kim H, Liu Y, Yang Y, Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118 |
Phf6 PHD finger protein 6 (Synonyms: 2700007B13Rik, 4931428F02Rik, mKIAA1823) | |
Results | Reference |
3 | J:229060 Franzoni E, Booker SA, Parthasarathy S, Rehfeld F, Grosser S, Srivatsa S, Fuchs HR, Tarabykin V, Vida I, Wulczyn FG, miR-128 regulates neuronal migration, outgrowth and intrinsic excitability via the intellectual disability gene Phf6. Elife. 2015;4 |
2* | J:126288 Voss AK, Gamble R, Collin C, Shoubridge C, Corbett M, Gecz J, Thomas T, Protein and gene expression analysis of Phf6, the gene mutated in the Borjeson-Forssman-Lehmann Syndrome of intellectual disability and obesity. Gene Expr Patterns. 2007 Oct;7(8):858-71 |
Phf8 PHD finger protein 8 (Synonyms: 9830141C09Rik, mKIAA1111) | |
Results | Reference |
2* | J:200889 Laumonnier F, Holbert S, Ronce N, Faravelli F, Lenzner S, Schwartz CE, Lespinasse J, Van Esch H, Lacombe D, Goizet C, Phan-Dinh Tuy F, van Bokhoven H, Fryns JP, Chelly J, Ropers HH, Moraine C, Hamel BC, Briault S, Mutations in PHF8 are associated with X linked mental retardation and cleft lip/cleft palate. J Med Genet. 2005 Oct;42(10):780-6 |
Phf10 PHD finger protein 10 (Synonyms: 1810055P05Rik, Baf45a) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
Phf13 PHD finger protein 13 (Synonyms: SPOC1) | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
Phf21a PHD finger protein 21A (Synonyms: 80kDa, Bhc80, Braf35/HDAC complex (Bhc), D030065N23Rik, MGC:29190, PFTF1) | |
Results | Reference |
2* | J:359190 Nagai M, Porter RS, Miyasato M, Wang A, Gavilan CM, Hughes ED, Wu MC, Saunders TL, Iwase S, Neuronal splicing of the unmethylated histone H3K4 reader, PHF21A, prevents excessive synaptogenesis. J Biol Chem. 2024 Nov;300(11):107881 |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1 | J:361726 Porter RS, An S, Gavilan MC, Nagai M, Murata-Nakamura Y, Zhou B, Bonefas KM, Dionne O, Manuel JM, St-Germain J, Gascon S, Kim J, Browning L, Laurent B, Cho US, Iwase S, Coordinated neuron-specific splicing events restrict nucleosome engagement of the LSD1 histone demethylase complex. Cell Rep. 2025 Jan 28;44(1):115213 |
Phgdh 3-phosphoglycerate dehydrogenase (Synonyms: 3-PGDH, 3PGDH, A10, PGAD, PGD, PGDH, SERA) | |
Results | Reference |
1* | J:354187 Hayashi Y, Kaneko J, Ito-Matsuoka Y, Takehara A, Funakoshi M, Maezawa S, Shirane K, Furuya S, Matsui Y, Control of epigenomic landscape and development of fetal male germ cells through L-serine metabolism. iScience. 2024 Sep 20;27(9):110702 |
Phlda2 pleckstrin homology like domain, family A, member 2 (Synonyms: Ipl, Tssc3) | |
Results | Reference |
1 | J:79882 Fitzpatrick GV, Soloway PD, Higgins MJ, Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1. Nat Genet. 2002 Nov;32(3):426-31 |
1 | J:93878 Salas M, John R, Saxena A, Barton S, Frank D, Fitzpatrick G, Higgins MJ, Tycko B, Placental growth retardation due to loss of imprinting of Phlda2. Mech Dev. 2004 Oct;121(10):1199-210 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
Phox2a paired-like homeobox 2a (Synonyms: Arix, Pmx2, Pmx2a, Px2a) | |
Results | Reference |
1* | J:130196 Alfonsi F, Filippi P, Salaun D, deLapeyriere O, Durbec P, LIFR beta plays a major role in neuronal identity determination and glial differentiation in the mouse facial nucleus. Dev Biol. 2008 Jan 1;313(1):267-78 |
1 | J:166770 Coppola E, d'Autreaux F, Rijli FM, Brunet JF, Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation. Development. 2010 Dec;137(24):4211-20 |
1 | J:126634 Coppola E, Pattyn A, Guthrie SC, Goridis C, Studer M, Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation. EMBO J. 2005 Dec 21;24(24):4392-403 |
1* | J:46409 Hirsch MR, Tiveron MC, Guillemot F, Brunet JF, Goridis C, Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system. Development. 1998 Feb;125(4):599-608 |
1 | J:79390 Huber K, Bruhl B, Guillemot F, Olson EN, Ernsberger U, Unsicker K, Development of chromaffin cells depends on MASH1 function. Development. 2002 Oct;129(20):4729-38 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
1 | J:152424 Jacob J, Storm R, Castro DS, Milton C, Pla P, Guillemot F, Birchmeier C, Briscoe J, Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain. Development. 2009 Jul;136(14):2477-85 |
1* | J:63720 Jacob J, Tiveron MC, Brunet JF, Guthrie S, Role of the target in the pathfinding of facial visceral motor axons. Mol Cell Neurosci. 2000 Jul;16(1):14-26 |
1* | J:332883 Rastegar-Pouyani S, Kennedy TE, Kania A, Somatotopy of Mouse Spinothalamic Innervation and the Localization of a Noxious Stimulus Requires Deleted in Colorectal Carcinoma Expression by Phox2a Neurons. J Neurosci. 2022 Oct 19;42(42):7885-7899 |
2 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
2* | J:286599 Song NN, Ma P, Zhang Q, Zhang L, Wang H, Zhang L, Zhu L, He CH, Mao B, Ding YQ, Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199 |
1* | J:44471 Tiveron MC, Hirsch MR, Brunet JF, The expression pattern of the transcription factor Phox2 delineates synaptic pathways of the autonomic nervous system. J Neurosci. 1996 Dec 1;16(23):7649-60 |
1 | J:343072 Vermeiren S, Cabochette P, Dannawi M, Desiderio S, San Jose AS, Achouri Y, Kricha S, Sitte M, Salinas-Riester G, Vanhollebeke B, Brunet JF, Bellefroid EJ, Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia. iScience. 2023 Dec 15;26(12):108364 |
1 | J:201733 Xu Y, Lopes C, Wende H, Guo Z, Cheng L, Birchmeier C, Ma Q, Ontogeny of excitatory spinal neurons processing distinct somatic sensory modalities. J Neurosci. 2013 Sep 11;33(37):14738-48 |
Phox2b paired-like homeobox 2b (Synonyms: Dilp1, GENA 269, NBPhox, Phox2b, Pmx2b, Px2b) | |
Results | Reference |
1* | J:130196 Alfonsi F, Filippi P, Salaun D, deLapeyriere O, Durbec P, LIFR beta plays a major role in neuronal identity determination and glial differentiation in the mouse facial nucleus. Dev Biol. 2008 Jan 1;313(1):267-78 |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1 | J:166770 Coppola E, d'Autreaux F, Rijli FM, Brunet JF, Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation. Development. 2010 Dec;137(24):4211-20 |
1 | J:155885 Dubreuil V, Thoby-Brisson M, Rallu M, Persson K, Pattyn A, Birchmeier C, Brunet JF, Fortin G, Goridis C, Defective respiratory rhythmogenesis and loss of central chemosensitivity in Phox2b mutants targeting retrotrapezoid nucleus neurons. J Neurosci. 2009 Nov 25;29(47):14836-46 |
1 | J:71881 Enomoto H, Crawford PA, Gorodinsky A, Heuckeroth RO, Johnson EM Jr, Milbrandt J, RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neurons. Development. 2001 Oct;128(20):3963-74 |
1 | J:249229 Espinosa-Medina I, Outin E, Picard CA, Chettouh Z, Dymecki S, Consalez GG, Coppola E, Brunet JF, Neurodevelopment. Parasympathetic ganglia derive from Schwann cell precursors. Science. 2014 Jul 4;345(6192):87-90 |
1 | J:237201 Espinosa-Medina I, Saha O, Boismoreau F, Chettouh Z, Rossi F, Richardson WD, Brunet JF, The sacral autonomic outflow is sympathetic. Science. 2016 Nov 18;354(6314):893-897 |
1* | J:46409 Hirsch MR, Tiveron MC, Guillemot F, Brunet JF, Goridis C, Control of noradrenergic differentiation and Phox2a expression by MASH1 in the central and peripheral nervous system. Development. 1998 Feb;125(4):599-608 |
1 | J:332402 Hockman D, Adameyko I, Kaucka M, Barraud P, Otani T, Hunt A, Hartwig AC, Sock E, Waithe D, Franck MCM, Ernfors P, Ehinger S, Howard MJ, Brown N, Reese J, Baker CVH, Striking parallels between carotid body glomus cell and adrenal chromaffin cell development. Dev Biol. 2018 Dec 1;444 Suppl 1(Suppl 1):S308-S324 |
1 | J:188329 Huang WH, Tupal S, Huang TW, Ward CS, Neul JL, Klisch TJ, Gray PA, Zoghbi HY, Atoh1 Governs the Migration of Postmitotic Neurons that Shape Respiratory Effectiveness at Birth and Chemoresponsiveness in Adulthood. Neuron. 2012 Sep 6;75(5):799-809 |
1 | J:79390 Huber K, Bruhl B, Guillemot F, Olson EN, Ernsberger U, Unsicker K, Development of chromaffin cells depends on MASH1 function. Development. 2002 Oct;129(20):4729-38 |
1* | J:96531 Huber K, Karch N, Ernsberger U, Goridis C, Unsicker K, The role of Phox2B in chromaffin cell development. Dev Biol. 2005 Mar 15;279(2):501-8 |
2 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
1 | J:92081 Ma X, Kawamoto S, Hara Y, Adelstein RS, A point mutation in the motor domain of nonmuscle myosin II-B impairs migration of distinct groups of neurons. Mol Biol Cell. 2004 Jun;15(6):2568-79 |
1 | J:295953 Niu X, Liu L, Wang T, Chuan X, Yu Q, Du M, Gu Y, Wang L, Mapping of Extrinsic Innervation of the Gastrointestinal Tract in the Mouse Embryo. J Neurosci. 2020 Aug 26;40(35):6691-6708 |
1 | J:76685 Ohshima T, Ogawa M, Takeuchi K, Takahashi S, Kulkarni AB, Mikoshiba K, Cyclin-dependent kinase 5/p35 contributes synergistically with Reelin/Dab1 to the positioning of facial branchiomotor and inferior olive neurons in the developing mouse hindbrain. J Neurosci. 2002 May 15;22(10):4036-44 |
1 | J:72062 Qian Y, Fritzsch B, Shirasawa S, Chen CL, Choi Y, Ma Q, Formation of brainstem (nor)adrenergic centers and first-order relay visceral sensory neurons is dependent on homeodomain protein Rnx/Tlx3. Genes Dev. 2001 Oct 1;15(19):2533-45 |
1 | J:155760 Rose MF, Ren J, Ahmad KA, Chao HT, Klisch TJ, Flora A, Greer JJ, Zoghbi HY, Math1 is essential for the development of hindbrain neurons critical for perinatal breathing. Neuron. 2009 Nov 12;64(3):341-54 |
1 | J:173638 Schmidt M, Huber L, Majdazari A, Schutz G, Williams T, Rohrer H, The transcription factors AP-2beta and AP-2alpha are required for survival of sympathetic progenitors and differentiated sympathetic neurons. Dev Biol. 2011 Jul 1;355(1):89-100 |
1 | J:357469 Sivori M, Dempsey B, Chettouh Z, Boismoreau F, Ayerdi M, et al., The pelvic organs receive no parasympathetic innervation. Elife. 2024;15 |
2* | J:286599 Song NN, Ma P, Zhang Q, Zhang L, Wang H, Zhang L, Zhu L, He CH, Mao B, Ding YQ, Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199 |
1 | J:201069 Stubbusch J, Narasimhan P, Huber K, Unsicker K, Rohrer H, Ernsberger U, Synaptic protein and pan-neuronal gene expression and their regulation by Dicer-dependent mechanisms differ between neurons and neuroendocrine cells. Neural Dev. 2013 Aug 20;8(1):16 |
1 | J:224366 Uesaka T, Nagashimada M, Enomoto H, Neuronal Differentiation in Schwann Cell Lineage Underlies Postnatal Neurogenesis in the Enteric Nervous System. J Neurosci. 2015 Jul 8;35(27):9879-88 |
1 | J:343072 Vermeiren S, Cabochette P, Dannawi M, Desiderio S, San Jose AS, Achouri Y, Kricha S, Sitte M, Salinas-Riester G, Vanhollebeke B, Brunet JF, Bellefroid EJ, Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia. iScience. 2023 Dec 15;26(12):108364 |
1* | J:195264 Vincentz JW, Firulli BA, Lin A, Spicer DB, Howard MJ, Firulli AB, Twist1 Controls a Cell-Specification Switch Governing Cell Fate Decisions within the Cardiac Neural Crest. PLoS Genet. 2013 Mar;9(3):e1003405 |
1 | J:81003 Young HM, Bergner AJ, Muller T, Acquisition of neuronal and glial markers by neural crest-derived cells in the mouse intestine. J Comp Neurol. 2003 Jan 27;456(1):1-11 |
1 | J:50258 Young HM, Hearn CJ, Ciampoli D, Southwell BR, Brunet JF, Newgreen DF, A single rostrocaudal colonization of the rodent intestine by enteric neuron precursors is revealed by the expression of Phox2b, Ret, and p75 and by explants grown under the kidney capsule or in organ culture. Dev Biol. 1998 Oct 1;202(1):67-84 |
1 | J:347625 Yu Q, Liu L, Du M, Muller D, Gu Y, Gao Z, Xin X, Gu Y, He M, Marquardt T, Wang L, Sacral Neural Crest-Independent Origin of the Enteric Nervous System in Mouse. Gastroenterology. 2024 Mar 5; |
Pi16 peptidase inhibitor 16 (Synonyms: 1200009H11Rik) | |
Results | Reference |
1 | J:359797 Coren L, Zaffryar-Eilot S, Odeh A, Kaganovsky A, Hasson P, Fibroblast diversification is an embryonic process dependent on muscle contraction. Cell Rep. 2024 Dec 4;43(12):115034 |
Pias1 protein inhibitor of activated STAT 1 (Synonyms: 2900068C24Rik, Ddxbp1, GBP) | |
Results | Reference |
1* | J:198379 Wang J, Sun Z, Zhang Z, Saadi I, Wang J, Li X, Gao S, Engle JJ, Kuburas A, Fu X, Yu W, Klein WH, Russo AF, Amendt BA, Protein inhibitors of activated STAT (Pias1 and Piasy) differentially regulate pituitary homeobox 2 (PITX2) transcriptional activity. J Biol Chem. 2013 May 3;288(18):12580-95 |
Pias2 protein inhibitor of activated STAT 2 (Synonyms: 6330408K17Rik, ARIP3, Dib, Miz1, PIASxalpha, PIASxb, PIASxbeta) | |
Results | Reference |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Pias4 protein inhibitor of activated STAT 4 (Synonyms: PIASy) | |
Results | Reference |
1* | J:63546 Sturm S, Koch M, White FA, Cloning and analysis of a murine PIAS family member, PIASgamma, in developing skin and neurons. J Mol Neurosci. 2000 Feb-Apr;14(1-2):107-21 |
1* | J:198379 Wang J, Sun Z, Zhang Z, Saadi I, Wang J, Li X, Gao S, Engle JJ, Kuburas A, Fu X, Yu W, Klein WH, Russo AF, Amendt BA, Protein inhibitors of activated STAT (Pias1 and Piasy) differentially regulate pituitary homeobox 2 (PITX2) transcriptional activity. J Biol Chem. 2013 May 3;288(18):12580-95 |
Piezo1 piezo-type mechanosensitive ion channel component 1 (Synonyms: Fam38a, Piezo1) | |
Results | Reference |
1* | J:347773 Kim HY, Kang B, Lee PR, Kim K, Hong GS, Expression patterns of Piezo1 in the developing mouse forebrain. Brain Struct Funct. 2024 Apr;229(3):759-773 |
1 | J:348078 Nie X, Abbasi Y, Chung MK, Piezo1 and Piezo2 collectively regulate jawbone development. Development. 2024 May 1;151(9):dev202386 |
1 | J:292430 Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, Zhang X, Zhou Y, Yadav PS, Lin J, Wu N, Zhao L, Huang D, Zhou S, Su P, Yang Y, Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ss-catenin. Elife. 2020 Mar 18;9:e52779 |
Piezo2 piezo-type mechanosensitive ion channel component 2 (Synonyms: 9030411M15Rik, 9430028L06Rik, Fam38b, Fam38b2, Piezo2) | |
Results | Reference |
1 | J:321844 Mochida Y, Ochiai K, Nagase T, Nonomura K, Akimoto Y, Fukuhara H, Sakai T, Matsumura G, Yamaguchi Y, Nagase M, Piezo2 expression and its alteration by mechanical forces in mouse mesangial cells and renin-producing cells. Sci Rep. 2022 Mar 10;12(1):4197 |
1 | J:348078 Nie X, Abbasi Y, Chung MK, Piezo1 and Piezo2 collectively regulate jawbone development. Development. 2024 May 1;151(9):dev202386 |
Pik3ca phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha (Synonyms: 6330412C24Rik, caPI3K, p110alpha) | |
Results | Reference |
1 | J:340406 Lai Y, Guo Y, Liao C, Mao C, Liu J, Ren C, Yang W, Luo L, Chen W, Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development. Sci Rep. 2023 Sep 13;13(1):15170 |
1 | J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410 |
1 | J:180006 Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T, NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54 |
Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 (Synonyms: p50alpha, p55alpha, p85alpha, PI3K) | |
Results | Reference |
1* | J:131397 Cho KW, Cho SW, Lee JM, Lee MJ, Gang HS, Jung HS, Expression of phosphorylated forms of ERK, MEK, PTEN and PI3K in mouse oral development. Gene Expr Patterns. 2008 Apr;8(4):284-290 |
1* | J:83700 Koyama N, Kashimata M, Sakashita H, Sakagami H, Gresik EW, EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland. Dev Dyn. 2003 Jun;227(2):216-26 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1 | J:180006 Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T, NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54 |
Pik3r4 phosphoinositide-3-kinase regulatory subunit 4 (Synonyms: p150, Vps15) | |
Results | Reference |
1 | J:258027 Gstrein T, Edwards A, Pristoupilova A, Leca I, Breuss M, Pilat-Carotta S, Hansen AH, Tripathy R, Traunbauer AK, Hochstoeger T, Rosoklija G, Repic M, Landler L, Stranecky V, Durnberger G, Keane TM, Zuber J, Adams DJ, Flint J, Honzik T, Gut M, Beltran S, Mechtler K, Sherr E, Kmoch S, Gut I, Keays DA, Mutations in Vps15 perturb neuronal migration in mice and are associated with neurodevelopmental disease in humans. Nat Neurosci. 2018 Feb;21(2):207-217 |
Pim1 proviral integration site 1 (Synonyms: Pim-1) | |
Results | Reference |
1* | J:42922 Allen JD, Verhoeven E, Domen J, van der Valk M, Berns A, Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc. Oncogene. 1997 Sep 4;15(10):1133-41 |
1* | J:91592 Mikkers H, Nawijn M, Allen J, Brouwers C, Verhoeven E, Jonkers J, Berns A, Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors. Mol Cell Biol. 2004 Jul;24(13):6104-15 |
Pim2 proviral integration site 2 (Synonyms: DXCch3, Pim-2) | |
Results | Reference |
1* | J:42922 Allen JD, Verhoeven E, Domen J, van der Valk M, Berns A, Pim-2 transgene induces lymphoid tumors, exhibiting potent synergy with c-myc. Oncogene. 1997 Sep 4;15(10):1133-41 |
1* | J:91592 Mikkers H, Nawijn M, Allen J, Brouwers C, Verhoeven E, Jonkers J, Berns A, Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors. Mol Cell Biol. 2004 Jul;24(13):6104-15 |
Pim3 proviral integration site 3 (Synonyms: Kid1, KID-1/kinase induced by depolarization, MGC:27707, MGC:37517) | |
Results | Reference |
1* | J:91592 Mikkers H, Nawijn M, Allen J, Brouwers C, Verhoeven E, Jonkers J, Berns A, Mice deficient for all PIM kinases display reduced body size and impaired responses to hematopoietic growth factors. Mol Cell Biol. 2004 Jul;24(13):6104-15 |
Pimreg PICALM interacting mitotic regulator (Synonyms: 2610008F03Rik, 6720460F02Rik, CATS, Fam64a) | |
Results | Reference |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Pink1 PTEN induced putative kinase 1 (Synonyms: 1190006F07Rik, brpk) | |
Results | Reference |
2 | J:171179 d'Amora M, Angelini C, Marcoli M, Cervetto C, Kitada T, Vallarino M, Expression of PINK1 in the brain, eye and ear of mouse during embryonic development. J Chem Neuroanat. 2011 Mar;41(2):73-85 |
1 | J:356661 Esteban-Martinez L, Sierra-Filardi E, McGreal RS, Salazar-Roa M, Marino G, Seco E, Durand S, Enot D, Grana O, Malumbres M, Cvekl A, Cuervo AM, Kroemer G, Boya P, Programmed mitophagy is essential for the glycolytic switch during cell differentiation. EMBO J. 2017 Jun 14;36(12):1688-1706 |
1 | J:333326 Suh J, Kim NK, Shim W, Lee SH, Kim HJ, Moon E, Sesaki H, Jang JH, Kim JE, Lee YS, Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab. 2023 Feb 7;35(2):345-360.e7 |
1 | J:267715 Wiwatpanit T, Lorenzen SM, Cantu JA, Foo CZ, Hogan AK, Marquez F, Clancy JC, Schipma MJ, Cheatham MA, Duggan A, Garcia-Anoveros J, Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1. Nature. 2018 Nov;563(7733):691-695 |
Pip prolactin induced protein (Synonyms: GCDFP-15, gross cystic disease fluid protein 15, mSMGP) | |
Results | Reference |
1* | J:84947 Lee B, Modha G, Watson PH, Dodd J, Troup S, Blanchard A, Myal Y, Expression of the mouse homologue for the human GCDFP-15/PIP gene during pre- and early post-natal development. Mol Cell Endocrinol. 2003 Jul 31;205(1-2):33-41 |
Pip4k2a phosphatidylinositol-5-phosphate 4-kinase, type II, alpha (Synonyms: Pip5k2a) | |
Results | Reference |
1 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
Pip5k1c phosphatidylinositol-4-phosphate 5-kinase, type 1 gamma (Synonyms: mKIAA0589, PIP5KIgamma) | |
Results | Reference |
1 | J:227887 Hara Y, Fukaya M, Tamaki H, Sakagami H, Type I phosphatidylinositol 4-phosphate 5-kinase gamma is required for neuronal migration in the mouse developing cerebral cortex. Eur J Neurosci. 2013 Sep;38(5):2659-71 |
Pip5kl1 phosphatidylinositol-4-phosphate 5-kinase-like 1 | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
Pisrt1 polled intersex syndrome regulated transcript 1 | |
Results | Reference |
1* | J:101893 Loffler KA, Combes AN, Wilhelm D, Beverdam A, Bowles J, Koopman P, Pisrt1, a gene implicated in XX sex reversal, is expressed in gonads of both sexes during mouse development. Mol Genet Metab. 2005 Sep-Oct;86(1-2):286-92 |
Pitpnm1 phosphatidylinositol transfer protein, membrane-associated 1 (Synonyms: DRES9, RdgB) | |
Results | Reference |
1 | J:42606 Rubboli F, Bulfone A, Bogni S, Marchitiello A, Zollo M, Borsani G, Ballabio A, Banfi S, A mammalian homologue of the Drosophila retinal degeneration B gene: implications for the evolution of phototransduction mechanisms. Genes Funct. 1997 Jun;1(3):205-13 |
Pitx1 paired-like homeodomain transcription factor 1 (Synonyms: Bft, Potx, P-OTX, Ptx1) | |
Results | Reference |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1 | J:89087 Lamolet B, Poulin G, Chu K, Guillemot F, Tsai MJ, Drouin J, Tpit-independent function of NeuroD1(BETA2) in pituitary corticotroph differentiation. Mol Endocrinol. 2004 Apr;18(4):995-1003 |
2* | J:228711 Lanctot C, Gauthier Y, Drouin J, Pituitary homeobox 1 (Ptx1) is differentially expressed during pituitary development. Endocrinology. 1999 Mar;140(3):1416-22 |
1 | J:168032 Zacharias AL, Lewandoski M, Rudnicki MA, Gage PJ, Pitx2 is an upstream activator of extraocular myogenesis and survival. Dev Biol. 2011 Jan 15;349(2):395-405 |
Pitx2 paired-like homeodomain transcription factor 2 (Synonyms: Brx1, Brx1a, Brx1b, Munc30, Otlx2, Pitx2a, Pitx2b, Pitx2c, Ptx2, Rieg, solurshin) | |
Results | Reference |
1* | J:67751 Campione M, Ros MA, Icardo JM, Piedra E, Christoffels VM, Schweickert A, Blum M, Franco D, Moorman AF, Pitx2 expression defines a left cardiac lineage of cells: evidence for atrial and ventricular molecular isomerism in the iv/iv mice. Dev Biol. 2001 Mar 1;231(1):252-64 |
1* | J:52601 Campione M, Steinbeisser H, Schweickert A, Deissler K, van Bebber F , Lowe LA , Nowotschin S , Viebahn C , Haffter P , Kuehn MR , Blum M, The homeobox gene Pitx2: mediator of asymmetric left-right signaling in vertebrate heart and gut looping. Development. 1999 Mar;126(6):1225-34 |
1 | J:199298 Cao H, Jheon A, Li X, Sun Z, Wang J, Florez S, Zhang Z, McManus MT, Klein OD, Amendt BA, The Pitx2:miR-200c/141:noggin pathway regulates Bmp signaling and ameloblast differentiation. Development. 2013 Aug;140(16):3348-59 |
1 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1* | J:39014 Gage PJ, Camper SA, Pituitary homeobox 2, a novel member of the bicoid-related family of homeobox genes, is a potential regulator of anterior structure formation. Hum Mol Genet. 1997 Mar;6(3):457-64 |
1* | J:136041 Gage PJ, Qian M, Wu D, Rosenberg KI, The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development. Dev Biol. 2008 May 1;317(1):310-24 |
1* | J:62068 Hjalt TA, Semina EV, Amendt BA, Murray JC, The Pitx2 protein in mouse development. Dev Dyn. 2000 May;218(1):195-200 |
1 | J:332137 Hu H, Duan Y, Wang K, Fu H, Liao Y, Wang T, Zhang Z, Kang F, Zhang B, Zhang H, Huo F, Yin Y, Chen G, Hu H, Cai H, Tian W, Li Z, Dental niche cells directly contribute to tooth reconstitution and morphogenesis. Cell Rep. 2022 Dec 6;41(10):111737 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:240480 Kapali J, Kabat BE, Schmidt KL, Stallings CE, Tippy M, Jung DO, Edwards BS, Nantie LB, Raeztman LT, Navratil AM, Ellsworth BS, Foxo1 Is Required for Normal Somatotrope Differentiation. Endocrinology. 2016 Nov;157(11):4351-4363 |
1 | J:203117 Li X, Venugopalan SR, Cao H, Pinho FO, Paine ML, Snead ML, Semina EV, Amendt BA, A model for the molecular underpinnings of tooth defects in Axenfeld-Rieger syndrome. Hum Mol Genet. 2014 Jan 1;23(1):194-208 |
1* | J:79853 Liu C, Liu W, Palie J, Lu MF, Brown NA, Martin JF, Pitx2c patterns anterior myocardium and aortic arch vessels and is required for local cell movement into atrioventricular cushions. Development. 2002 Nov;129(21):5081-91 |
1 | J:87220 Liu W, Selever J, Lu MF, Martin JF, Genetic dissection of Pitx2 in craniofacial development uncovers new functions in branchial arch morphogenesis, late aspects of tooth morphogenesis and cell migration. Development. 2003 Dec;130(25):6375-85 |
1* | J:88779 Martin DM, Skidmore JM, Philips ST, Vieira C, Gage PJ, Condie BG, Raphael Y, Martinez S, Camper SA, PITX2 is required for normal development of neurons in the mouse subthalamic nucleus and midbrain. Dev Biol. 2004 Mar 1;267(1):93-108 |
1* | J:46754 Mitsiadis TA, Mucchielli ML, Raffo S, Proust JP, Koopman P, Goridis C, Expression of the transcription factors Otlx2, Barx1 and Sox9 during mouse odontogenesis. Eur J Oral Sci. 1998 Jan;106 Suppl 1:112-6 |
1* | J:38461 Mucchielli ML, Martinez S, Pattyn A, Goridis C, Brunet JF, Otlx2, an Otx-related homeobox gene expressed in the pituitary gland and in a restricted pattern in the forebrain. Mol Cell Neurosci. 1996;8(4):258-71 |
1 | J:43528 Mucchielli ML, Mitsiadis TA, Raffo S, Brunet JF, Proust JP, Goridis C, Mouse Otlx2/RIEG expression in the odontogenic epithelium precedes tooth initiation and requires mesenchyme-derived signals for its maintenance. Dev Biol. 1997 Sep 15;189(2):275-84 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
1 | J:167837 Waite MR, Skidmore JM, Billi AC, Martin JF, Martin DM, GABAergic and glutamatergic identities of developing midbrain Pitx2 neurons. Dev Dyn. 2011 Feb;240(2):333-46 |
1 | J:256746 Wang X, Shan X, Gregory-Evans CY, A mouse model of aniridia reveals the in vivo downstream targets of Pax6 driving iris and ciliary body development in the eye. Biochim Biophys Acta. 2017 Jan;1863(1):60-67 |
1 | J:168032 Zacharias AL, Lewandoski M, Rudnicki MA, Gage PJ, Pitx2 is an upstream activator of extraocular myogenesis and survival. Dev Biol. 2011 Jan 15;349(2):395-405 |
1 | J:157468 Zagoraiou L, Akay T, Martin JF, Brownstone RM, Jessell TM, Miles GB, A cluster of cholinergic premotor interneurons modulates mouse locomotor activity. Neuron. 2009 Dec 10;64(5):645-62 |
Pitx3 paired-like homeodomain transcription factor 3 (Synonyms: Ptx3) | |
Results | Reference |
2 | J:297714 Brignani S, Raj DDA, Schmidt ERE, Dudukcu O, Adolfs Y, De Ruiter AA, Rybiczka-Tesulov M, Verhagen MG, van der Meer C, Broekhoven MH, Moreno-Bravo JA, Grossouw LM, Dumontier E, Cloutier JF, Chedotal A, Pasterkamp RJ, Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development. Neuron. 2020 Aug 19;107(4):684-702.e9 |
1* | J:364202 Kouwenhoven WM, Robinson EJ, Hamberg D, von Oerthel L, Smidt MP, van der Heide LP, The absence of Pitx3 results in postnatal loss of dopamine neurons and is associated with an increase in the pro-apoptotic Bcl2 factor Noxa and cleaved caspase 3. Cell Death Dis. 2025 Apr 1;16(1):230 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
1* | J:133341 Vives J, Sasajala P, Chang KH, Zhao S, Li M, A mouse model for tracking nigrostriatal dopamine neuron axon growth. Genesis. 2008 Mar;46(3):125-31 |
Piwil1 piwi-like RNA-mediated gene silencing 1 (Synonyms: MIWI) | |
Results | Reference |
1* | J:71909 Kuramochi-Miyagawa S, Kimura T, Yomogida K, Kuroiwa A, Tadokoro Y, Fujita Y, Sato M, Matsuda Y, Nakano T, Two mouse piwi-related genes: miwi and mili. Mech Dev. 2001 Oct;108(1-2):121-33 |
1 | J:170319 Yabuta Y, Ohta H, Abe T, Kurimoto K, Chuma S, Saitou M, TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice. J Cell Biol. 2011 Mar 7;192(5):781-95 |
Piwil2 piwi-like RNA-mediated gene silencing 2 (Synonyms: mili, Miwi like) | |
Results | Reference |
1 | J:184034 De Fazio S, Bartonicek N, Di Giacomo M, Abreu-Goodger C, Sankar A, Funaya C, Antony C, Moreira PN, Enright AJ, O'Carroll D, The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements. Nature. 2011 Dec 8;480(7376):259-63 |
2 | J:238224 Fu Q, Pandey RR, Leu NA, Pillai RS, Wang PJ, Mutations in the MOV10L1 ATP Hydrolysis Motif Cause piRNA Biogenesis Failure and Male Sterility in Mice. Biol Reprod. 2016 Nov 1;95(5):103 |
1 | J:326085 Huang TC, Wang YF, Vazquez-Ferrer E, Theofel I, Requena CE, Hanna CW, Kelsey G, Hajkova P, Sex-specific chromatin remodelling safeguards transcription in germ cells. Nature. 2021 Dec;600(7890):737-742 |
1 | J:356915 Ichiyanagi T, Ichiyanagi K, Ogawa A, Kuramochi-Miyagawa S, Nakano T, Chuma S, Sasaki H, Udono H, HSP90alpha plays an important role in piRNA biogenesis and retrotransposon repression in mouse. Nucleic Acids Res. 2014 Oct 29;42(19):11903-11 |
2 | J:312495 Kojima-Kita K, Kuramochi-Miyagawa S, Nakayama M, Miyata H, Jacobsen SE, Ikawa M, Koseki H, Nakano T, MORC3, a novel MIWI2 association partner, as an epigenetic regulator of piRNA dependent transposon silencing in male germ cells. Sci Rep. 2021 Oct 14;11(1):20472 |
1* | J:71909 Kuramochi-Miyagawa S, Kimura T, Yomogida K, Kuroiwa A, Tadokoro Y, Fujita Y, Sato M, Matsuda Y, Nakano T, Two mouse piwi-related genes: miwi and mili. Mech Dev. 2001 Oct;108(1-2):121-33 |
2* | J:159518 Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Takamatsu K, Chuma S, Kojima-Kita K, Shiromoto Y, Asada N, Toyoda A, Fujiyama A, Totoki Y, Shibata T, Kimura T, Nakatsuji N, Noce T, Sasaki H, Nakano T, MVH in piRNA processing and gene silencing of retrotransposons. Genes Dev. 2010 May;24(9):887-92 |
1* | J:133343 Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Totoki Y, Toyoda A, Ikawa M, Asada N, Kojima K, Yamaguchi Y, Ijiri TW, Hata K, Li E, Matsuda Y, Kimura T, Okabe M, Sakaki Y, Sasaki H, Nakano T, DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev. 2008 Apr 1;22(7):908-17 |
1 | J:363950 Lee S, Kuramochi-Miyagawa S, Nagamori I, Nakano T, Effects of transgene insertion loci and copy number on Dnmt3L gene silencing through antisense transgene-derived PIWI-interacting RNAs. RNA. 2022;28(5):683-696 |
2* | J:277128 Shiromoto Y, Kuramochi-Miyagawa S, Nagamori I, Chuma S, Arakawa T, Nishimura T, Hasuwa H, Tachibana T, Ikawa M, Nakano T, GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice. Biol Reprod. 2019 Jul 1;101(1):248-256 |
1 | J:156018 Shoji M, Tanaka T, Hosokawa M, Reuter M, Stark A, Kato Y, Kondoh G, Okawa K, Chujo T, Suzuki T, Hata K, Martin SL, Noce T, Kuramochi-Miyagawa S, Nakano T, Sasaki H, Pillai RS, Nakatsuji N, Chuma S, The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell. 2009 Dec;17(6):775-87 |
2 | J:306454 Tan K, Kim ME, Song HW, Skarbrevik D, Babajanian E, Bedrosian TA, Gage FH, Wilkinson MF, The Rhox gene cluster suppresses germline LINE1 transposition. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2024785118 |
2 | J:221349 Vourekas A, Zheng K, Fu Q, Maragkakis M, Alexiou P, Ma J, Pillai RS, Mourelatos Z, Wang PJ, The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing. Genes Dev. 2015 Mar 15;29(6):617-29 |
1 | J:169934 Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A, Hoki Y, Fujiyama A, Shibata T, Sado T, Noce T, Nakano T, Nakatsuji N, Lin H, Sasaki H, MITOPLD Is a Mitochondrial Protein Essential for Nuage Formation and piRNA Biogenesis in the Mouse Germline. Dev Cell. 2011 Mar 15;20(3):364-75 |
1 | J:170319 Yabuta Y, Ohta H, Abe T, Kurimoto K, Chuma S, Saitou M, TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice. J Cell Biol. 2011 Mar 7;192(5):781-95 |
1* | J:288732 Yang F, Lan Y, Pandey RR, Homolka D, Berger SL, Pillai RS, Bartolomei MS, Wang PJ, TEX15 associates with MILI and silences transposable elements in male germ cells. Genes Dev. 2020 Jun 1;34(11-12):745-750 |
Piwil4 piwi-like RNA-mediated gene silencing 4 (Synonyms: 9230101H05Rik, Miwi2, MIWI2) | |
Results | Reference |
1 | J:155865 Aravin AA, van der Heijden GW, Castaneda J, Vagin VV, Hannon GJ, Bortvin A, Cytoplasmic compartmentalization of the fetal piRNA pathway in mice. PLoS Genet. 2009 Dec;5(12):e1000764 |
1 | J:184034 De Fazio S, Bartonicek N, Di Giacomo M, Abreu-Goodger C, Sankar A, Funaya C, Antony C, Moreira PN, Enright AJ, O'Carroll D, The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements. Nature. 2011 Dec 8;480(7376):259-63 |
1* | J:355681 Dias Mirandela M, Zoch A, Leismann J, Webb S, Berrens RV, Valsakumar D, Kabayama Y, Auchynnikava T, Schito M, Chowdhury T, MacLeod D, Xiang X, Zou J, Rappsilber J, Allshire RC, Voigt P, Cook AG, Barau J, O'Carroll D, Two-factor authentication underpins the precision of the piRNA pathway. Nature. 2024 Oct;634(8035):979-985 |
1 | J:238224 Fu Q, Pandey RR, Leu NA, Pillai RS, Wang PJ, Mutations in the MOV10L1 ATP Hydrolysis Motif Cause piRNA Biogenesis Failure and Male Sterility in Mice. Biol Reprod. 2016 Nov 1;95(5):103 |
1 | J:356915 Ichiyanagi T, Ichiyanagi K, Ogawa A, Kuramochi-Miyagawa S, Nakano T, Chuma S, Sasaki H, Udono H, HSP90alpha plays an important role in piRNA biogenesis and retrotransposon repression in mouse. Nucleic Acids Res. 2014 Oct 29;42(19):11903-11 |
1 | J:252799 Itou D, Shiromoto Y, Yukiho SY, Ishii C, Nishimura T, Ogonuki N, Ogura A, Hasuwa H, Fujihara Y, Kuramochi-Miyagawa S, Nakano T, Induction of DNA methylation by artificial piRNA production in male germ cells. Curr Biol. 2015 Mar 30;25(7):901-6 |
2 | J:312495 Kojima-Kita K, Kuramochi-Miyagawa S, Nakayama M, Miyata H, Jacobsen SE, Ikawa M, Koseki H, Nakano T, MORC3, a novel MIWI2 association partner, as an epigenetic regulator of piRNA dependent transposon silencing in male germ cells. Sci Rep. 2021 Oct 14;11(1):20472 |
2* | J:159518 Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Takamatsu K, Chuma S, Kojima-Kita K, Shiromoto Y, Asada N, Toyoda A, Fujiyama A, Totoki Y, Shibata T, Kimura T, Nakatsuji N, Noce T, Sasaki H, Nakano T, MVH in piRNA processing and gene silencing of retrotransposons. Genes Dev. 2010 May;24(9):887-92 |
1* | J:133343 Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Totoki Y, Toyoda A, Ikawa M, Asada N, Kojima K, Yamaguchi Y, Ijiri TW, Hata K, Li E, Matsuda Y, Kimura T, Okabe M, Sakaki Y, Sasaki H, Nakano T, DNA methylation of retrotransposon genes is regulated by Piwi family members MILI and MIWI2 in murine fetal testes. Genes Dev. 2008 Apr 1;22(7):908-17 |
1 | J:363950 Lee S, Kuramochi-Miyagawa S, Nagamori I, Nakano T, Effects of transgene insertion loci and copy number on Dnmt3L gene silencing through antisense transgene-derived PIWI-interacting RNAs. RNA. 2022;28(5):683-696 |
1* | J:271628 Nagamori I, Kobayashi H, Nishimura T, Yamagishi R, Katahira J, Kuramochi-Miyagawa S, Kono T, Nakano T, Relationship between PIWIL4-Mediated H3K4me2 Demethylation and piRNA-Dependent DNA Methylation. Cell Rep. 2018 Oct 9;25(2):350-356 |
2 | J:291848 Schopp T, Zoch A, Berrens RV, Auchynnikava T, Kabayama Y, Vasiliauskaite L, Rappsilber J, Allshire RC, O'Carroll D, TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing. Nat Commun. 2020 Jul 27;11(1):3739 |
2* | J:277128 Shiromoto Y, Kuramochi-Miyagawa S, Nagamori I, Chuma S, Arakawa T, Nishimura T, Hasuwa H, Tachibana T, Ikawa M, Nakano T, GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice. Biol Reprod. 2019 Jul 1;101(1):248-256 |
1 | J:156018 Shoji M, Tanaka T, Hosokawa M, Reuter M, Stark A, Kato Y, Kondoh G, Okawa K, Chujo T, Suzuki T, Hata K, Martin SL, Noce T, Kuramochi-Miyagawa S, Nakano T, Sasaki H, Pillai RS, Nakatsuji N, Chuma S, The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell. 2009 Dec;17(6):775-87 |
1 | J:262370 Vasiliauskaite L, Vitsios D, Berrens RV, Carrieri C, Reik W, Enright AJ, O'Carroll D, A MILI-independent piRNA biogenesis pathway empowers partial germline reprogramming. Nat Struct Mol Biol. 2017 Jul;24(7):604-606 |
1 | J:221349 Vourekas A, Zheng K, Fu Q, Maragkakis M, Alexiou P, Ma J, Pillai RS, Mourelatos Z, Wang PJ, The RNA helicase MOV10L1 binds piRNA precursors to initiate piRNA processing. Genes Dev. 2015 Mar 15;29(6):617-29 |
1 | J:169934 Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A, Hoki Y, Fujiyama A, Shibata T, Sado T, Noce T, Nakano T, Nakatsuji N, Lin H, Sasaki H, MITOPLD Is a Mitochondrial Protein Essential for Nuage Formation and piRNA Biogenesis in the Mouse Germline. Dev Cell. 2011 Mar 15;20(3):364-75 |
1 | J:243488 Wenda JM, Homolka D, Yang Z, Spinelli P, Sachidanandam R, Pandey RR, Pillai RS, Distinct Roles of RNA Helicases MVH and TDRD9 in PIWI Slicing-Triggered Mammalian piRNA Biogenesis and Function. Dev Cell. 2017 Jun 19;41(6):623-637.e9 |
1 | J:170319 Yabuta Y, Ohta H, Abe T, Kurimoto K, Chuma S, Saitou M, TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice. J Cell Biol. 2011 Mar 7;192(5):781-95 |
1* | J:295943 Zoch A, Auchynnikava T, Berrens RV, Kabayama Y, Schopp T, Heep M, Vasiliauskaite L, Perez-Rico YA, Cook AG, Shkumatava A, Rappsilber J, Allshire RC, O'Carroll D, SPOCD1 is an essential executor of piRNA-directed de novo DNA methylation. Nature. 2020 Aug;584(7822):635-639 |
1 | J:346376 Zoch A, Konieczny G, Auchynnikava T, Stallmeyer B, Rotte N, Heep M, Berrens RV, Schito M, Kabayama Y, Schopp T, Kliesch S, Houston B, Nagirnaja L, O'Bryan MK, Aston KI, Conrad DF, Rappsilber J, Allshire RC, Cook AG, Tuttelmann F, O'Carroll D, C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line. Mol Cell. 2024 Mar 21;84(6):1021-1035.e11 |
Pkd1 polycystin 1, transient receptor potential channel interacting (Synonyms: PC-1, PC1, polycystin-1) | |
Results | Reference |
2* | J:40260 Geng L, Segal Y, Pavlova A, Barros EJ, Lohning C, Lu W, Nigam SK , Frischauf AM , Reeders ST , Zhou J, Distribution and developmentally regulated expression of murine polycystin. Am J Physiol. 1997 Apr;272(4 Pt 2):F451-9 |
1* | J:54093 Guillaume R, D'Agati V, Daoust M, Trudel M, Murine Pkd1 is a developmentally regulated gene from morula to adulthood: role in tissue condensation and patterning. Dev Dyn. 1999 Apr;214(4):337-48 |
1* | J:62085 Guillaume R, Trudel M, Distinct and common developmental expression patterns of the murine pkd2 and pkd1 genes. Mech Dev. 2000 May;93(1-2):179-83 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
3* | J:72627 Lu W, Shen X, Pavlova A, Lakkis M, Ward CJ, Pritchard L, Harris PC, Genest DR, Perez-Atayde AR, Zhou J, Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects. Hum Mol Genet. 2001 Oct 1;10(21):2385-96 |
1 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
1* | J:204460 Nie X, Arend LJ, Pkd1 is required for male reproductive tract development. Mech Dev. 2013 Nov-Dec;130(11-12):567-76 |
1 | J:214978 Nie X, Arend LJ, Novel roles of Pkd2 in male reproductive system development. Differentiation. 2014 Mar-Apr;87(3-4):161-71 |
1 | J:125042 Pierreux CE, Poll AV, Kemp CR, Clotman F, Maestro MA, Cordi S, Ferrer J, Leyns L, Rousseau GG, Lemaigre FP, The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. Gastroenterology. 2006 Feb;130(2):532-41 |
1 | J:176236 Steigelman KA, Lelli A, Wu X, Gao J, Lin S, Piontek K, Wodarczyk C, Boletta A, Kim H, Qian F, Germino G, Geleoc GS, Holt JR, Zuo J, Polycystin-1 is required for stereocilia structure but not for mechanotransduction in inner ear hair cells. J Neurosci. 2011 Aug 24;31(34):12241-50 |
1 | J:127628 Yu S, Hackmann K, Gao J, He X, Piontek K, Garcia Gonzalez MA, Menezes LF, Xu H, Germino GG, Zuo J, Qian F, Essential role of cleavage of Polycystin-1 at G protein-coupled receptor proteolytic site for kidney tubular structure. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18688-93 |
Pkd2 polycystin 2, transient receptor potential cation channel (Synonyms: C030034P18Rik, PC2, polycystin-2, TRPP2) | |
Results | Reference |
1* | J:62085 Guillaume R, Trudel M, Distinct and common developmental expression patterns of the murine pkd2 and pkd1 genes. Mech Dev. 2000 May;93(1-2):179-83 |
1* | J:152213 Markowitz GS, Cai Y, Li L, Wu G, Ward LC, Somlo S, D'Agati VD, Polycystin-2 expression is developmentally regulated. Am J Physiol. 1999 Jul;277(1 Pt 2):F17-25 |
1* | J:77401 Pennekamp P, Karcher C, Fischer A, Schweickert A, Skryabin B, Horst J, Blum M, Dworniczak B, The ion channel polycystin-2 is required for left-right axis determination in mice. Curr Biol. 2002 Jun 4;12(11):938-43 |
1 | J:125042 Pierreux CE, Poll AV, Kemp CR, Clotman F, Maestro MA, Cordi S, Ferrer J, Leyns L, Rousseau GG, Lemaigre FP, The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. Gastroenterology. 2006 Feb;130(2):532-41 |
Pkdcc protein kinase domain containing, cytoplasmic (Synonyms: Adtk1, ESTM17, MAd1, Vlk) | |
Results | Reference |
1* | J:199462 Probst S, Zeller R, Zuniga A, The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development. Differentiation. 2013 Apr-Jun;85(4-5):121-30 |
Pkhd1 polycystic kidney and hepatic disease 1 (Synonyms: FPC, tigmin) | |
Results | Reference |
1 | J:80866 Nagasawa Y, Matthiesen S, Onuchic LF, Hou X, Bergmann C, Esquivel E, Senderek J, Ren Z, Zeltner R, Furu L, Avner E, Moser M, Somlo S, Guay-Woodford L, Buttner R, Zerres K, Germino GG, Identification and characterization of Pkhd1, the mouse orthologue of the human ARPKD gene. J Am Soc Nephrol. 2002 Sep;13(9):2246-58 |
1 | J:125042 Pierreux CE, Poll AV, Kemp CR, Clotman F, Maestro MA, Cordi S, Ferrer J, Leyns L, Rousseau GG, Lemaigre FP, The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. Gastroenterology. 2006 Feb;130(2):532-41 |
Pkm pyruvate kinase, muscle (Synonyms: Pk-2, Pk-3, Pk3, Pkm2) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
3 | J:304342 Magadum A, Singh N, Kurian AA, Munir I, Mehmood T, Brown K, Sharkar MTK, Chepurko E, Sassi Y, Oh JG, Lee P, Santos CXC, Gaziel-Sovran A, Zhang G, Cai CL, Kho C, Mayr M, Shah AM, Hajjar RJ, Zangi L, Pkm2 Regulates Cardiomyocyte Cell Cycle and Promotes Cardiac Regeneration. Circulation. 2020 Apr 14;141(15):1249-1265 |
1 | J:326253 Ni L, Lin B, Hu L, Zhang R, Fu F, Shen M, Yang J, Shi D, Pyruvate Kinase M2 Protects Heart from Pressure Overload-Induced Heart Failure by Phosphorylating RAC1. J Am Heart Assoc. 2022 Jun 7;11(11):e024854 |
1 | J:213479 Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, Yoshida N, PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Cereb Cortex. 2013 Aug;23(8):1824-35 |
2 | J:361525 Wu M, Jia G, Liu Y, Lou Y, Li Y, Xia M, Li H, Li W, PKM2 controls cochlear development through lactate-dependent transcriptional regulation. Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2410829122 |
Pknox1 Pbx/knotted 1 homeobox (Synonyms: D17Wsu76e, PREP1) | |
Results | Reference |
1* | J:56023 Ferretti E, Schulz H, Talarico D, Blasi F, Berthelsen J, The PBX-regulating protein PREP1 is present in different PBX-complexed forms in mouse. Mech Dev. 1999 May;83(1-2):53-64 |
Pknox2 Pbx/knotted 1 homeobox 2 (Synonyms: D230005H23Rik, Prep2) | |
Results | Reference |
1* | J:80127 Haller K, Rambaldi I, Kovacs EN, Daniels E, Featherstone M, Prep2: cloning and expression of a new prep family member. Dev Dyn. 2002 Nov;225(3):358-64 |
Plac1 placental specific protein 1 (Synonyms: DXWsu72e, Epcs26, Oosp2l) | |
Results | Reference |
1* | J:285868 Kong X, Jackman SM, Fant ME, Plac1 (placenta-specific 1) is widely expressed during fetal development and is associated with a lethal form of hydrocephalus. Birth Defects Res A Clin Mol Teratol. 2013 Sep;97(9):571-7 |
Plac8 placenta-specific 8 (Synonyms: C15, D5Wsu111e, onzin) | |
Results | Reference |
1* | J:83692 Galaviz-Hernandez C, Stagg C, de Ridder G, Tanaka TS, Ko MS, Schlessinger D, Nagaraja R, Plac8 and Plac9, novel placental-enriched genes identified through microarray analysis. Gene. 2003 May 8;309(2):81-9 |
Plac9 placenta specific 9 (Synonyms: Gm10393, Gm9780, Plac9, Plac9a, Plac9b) | |
Results | Reference |
1* | J:83692 Galaviz-Hernandez C, Stagg C, de Ridder G, Tanaka TS, Ko MS, Schlessinger D, Nagaraja R, Plac8 and Plac9, novel placental-enriched genes identified through microarray analysis. Gene. 2003 May 8;309(2):81-9 |
Plag1 pleiomorphic adenoma gene 1 | |
Results | Reference |
1* | J:96846 Hensen K, Braem C, Declercq J, Van Dyck F, Dewerchin M, Fiette L, Denef C, Van de Ven WJ, Targeted disruption of the murine Plag1 proto-oncogene causes growth retardation and reduced fertility. Dev Growth Differ. 2004 Oct;46(5):459-70 |
Plagl1 pleiomorphic adenoma gene-like 1 (Synonyms: Zac1) | |
Results | Reference |
1* | J:226471 Adnani L, Langevin LM, Gautier E, Dixit R, Parsons K, Li S, Kaushik G, Wilkinson G, Wilson R, Childs S, Nguyen MD, Journot L, Dehay C, Schuurmans C, Zac1 Regulates the Differentiation and Migration of Neocortical Neurons via Pac1. J Neurosci. 2015 Sep 30;35(39):13430-47 |
1* | J:173507 Du X, Rousseau M, Ounissi-Benkalha H, Marchand L, Jetha A, Paraskevas S, Goodyer C, Polychronakos C, Differential expression pattern of ZAC in developing mouse and human pancreas. J Mol Histol. 2011 Apr;42(2):129-36 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Plagl2 pleiomorphic adenoma gene-like 2 (Synonyms: mKIAA0198) | |
Results | Reference |
2* | J:130260 Van Dyck F, Braem CV, Chen Z, Declercq J, Deckers R, Kim BM, Ito S, Wu MK, Cohen DE, Dewerchin M, Derua R, Waelkens E, Fiette L, Roebroek A, Schuit F, Van de Ven WJ, Shivdasani RA, Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons. Cell Metab. 2007 Nov;6(5):406-13 |
Plat plasminogen activator, tissue (Synonyms: D8Ertd2e, MGC:18508, t-PA, tPA) | |
Results | Reference |
1* | J:99963 Collinge JE, Simirskii VN, Duncan MK, Expression of tissue plasminogen activator during eye development. Exp Eye Res. 2005 Jul;81(1):90-6 |
2* | J:24334 Lefebvre O, Regnier C, Chenard MP, Wendling C, Chambon P, Basset P, Rio MC, Developmental expression of mouse stromelysin-3 mRNA. Development. 1995 Apr;121(4):947-55 |
2 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
Plau plasminogen activator, urokinase (Synonyms: u-PA, uPA, urokinase-type plasminogen activator) | |
Results | Reference |
2* | J:24334 Lefebvre O, Regnier C, Chenard MP, Wendling C, Chambon P, Basset P, Rio MC, Developmental expression of mouse stromelysin-3 mRNA. Development. 1995 Apr;121(4):947-55 |
1 | J:107650 Miskin R, Masos T, Shoham Z, Williams-Simons L, Urokinase-type Plasminogen Activator mRNA is Expressed in Normal Developing Teeth and Leads to Abnormal Incisor Enamel in alphaMUPA Transgenic Mice. Transgenic Res. 2006 Apr;15(2):241-54 |
Plcb2 phospholipase C, beta 2 (Synonyms: B230205M18Rik) | |
Results | Reference |
1 | J:186296 Saqui-Salces M, Keeley TM, Grosse AS, Qiao XT, El-Zaatari M, Gumucio DL, Samuelson LC, Merchant JL, Gastric tuft cells express DCLK1 and are expanded in hyperplasia. Histochem Cell Biol. 2011 Aug;136(2):191-204 |
Plce1 phospholipase C, epsilon 1 (Synonyms: 4933403A21Rik, PLCepsilon) | |
Results | Reference |
1* | J:66491 Tidhar A, Reichenstein M, Cohen D, Faerman A, Copeland NG, Gilbert DJ, Jenkins NA, Shani M, A novel transgenic marker for migrating limb muscle precursors and for vascular smooth muscle cells. Dev Dyn. 2001 Jan;220(1):60-73 |
Plcg1 phospholipase C, gamma 1 (Synonyms: Cded, Plc-1, Plcg-1, Plc-gamma1) | |
Results | Reference |
1* | J:83700 Koyama N, Kashimata M, Sakashita H, Sakagami H, Gresik EW, EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland. Dev Dyn. 2003 Jun;227(2):216-26 |
Plch2 phospholipase C, eta 2 (Synonyms: A930027K05Rik, PLCeta2, Plcl4) | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Pld6 phospholipase D family member 6 (Synonyms: 4933433K01Rik, mitoPLD, Zuc) | |
Results | Reference |
2 | J:169934 Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A, Hoki Y, Fujiyama A, Shibata T, Sado T, Noce T, Nakano T, Nakatsuji N, Lin H, Sasaki H, MITOPLD Is a Mitochondrial Protein Essential for Nuage Formation and piRNA Biogenesis in the Mouse Germline. Dev Cell. 2011 Mar 15;20(3):364-75 |
Plec plectin (Synonyms: Plec1) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
1* | J:350103 Kantaputra P, Daroontum T, Kitiyamas K, Piyakhunakorn P, Kawasaki K, Sathienkijkanchai A, Wasant P, Vatanavicharn N, Yasanga T, Kaewgahya M, Tongsima S, Cox TC, Arold ST, Ohazama A, Ngamphiw C, Homozygosity for a Rare Plec Variant Suggests a Contributory Role in Congenital Insensitivity to Pain. Int J Mol Sci. 2024 Jun 8;25(12) |
2 | J:252201 Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A, p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct;137(10):2157-2167 |
Plekha1 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1 (Synonyms: C920009D07Rik, TAPP1) | |
Results | Reference |
1 | J:320489 Chen Y, Mei R, Teng P, Yang A, Hu X, Zhang Z, Qiu M, Zhao X, TAPP1 inhibits the differentiation of oligodendrocyte precursor cells via suppressing the Mek/Erk pathway. Neurosci Bull. 2015 Oct;31(5):517-26 |
Plekha6 pleckstrin homology domain containing, family A member 6 (Synonyms: Pepp3) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Plekhm1 pleckstrin homology domain containing, family M (with RUN domain) member 1 (Synonyms: AP162, B2, D330036J23Rik) | |
Results | Reference |
1* | J:356303 Zhao Y, Zheng D, Cvekl A, A comprehensive spatial-temporal transcriptomic analysis of differentiating nascent mouse lens epithelial and fiber cells. Exp Eye Res. 2018 Oct;175:56-72 |
Plet1 placenta expressed transcript 1 (Synonyms: 0610037B23Rik, 1600029D21Rik, PLET1) | |
Results | Reference |
1 | J:290414 Li J, Gordon J, Chen ELY, Xiao S, Wu L, Zuniga-Pflucker JC, Manley NR, NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development. Development. 2020 Jun 22;147(12):dev178988 |
1 | J:291487 Liu D, Kousa AI, O'Neill KE, Rouse P, Popis M, Farley AM, Tomlinson SR, Ulyanchenko S, Guillemot F, Seymour PA, Jorgensen MC, Serup P, Koch U, Radtke F, Blackburn CC, Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development. Development. 2020 Jun 22;147(12):dev178582 |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Plin1 perilipin 1 (Synonyms: 6030432J05Rik, Peri, perilipin A, perilipin B, Plin) | |
Results | Reference |
2* | J:239792 Hong KY, Bae H, Park I, Park DY, Kim KH, Kubota Y, Cho ES, Kim H, Adams RH, Yoo OJ, Koh GY, Perilipin+ embryonic preadipocytes actively proliferate along growing vasculatures for adipose expansion. Development. 2015 Aug 01;142(15):2623-32 |
1* | J:199242 Schulz TJ, Tseng YH, Brown adipose tissue: development, metabolism and beyond. Biochem J. 2013 Jul 15;453(2):167-78 |
1 | J:238410 Sun C, Berry WL, Olson LE, PDGFRalpha controls the balance of stromal and adipogenic cells during adipose tissue organogenesis. Development. 2017 Jan 01;144(1):83-94 |
1 | J:216370 Wang W, Kissig M, Rajakumari S, Huang L, Lim HW, Won KJ, Seale P, Ebf2 is a selective marker of brown and beige adipogenic precursor cells. Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14466-71 |
1* | J:236180 Zhou H, Black SM, Benson TW, Weintraub NL, Chen W, Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is Not Required for Brown Adipogenesis but Regulates Brown Adipose Tissue Development and Function. Mol Cell Biol. 2016 Aug 1;36(15):2027-38 |
Plin2 perilipin 2 (Synonyms: Adfp, adipophilin, ADPH, Adrp) | |
Results | Reference |
1 | J:239948 Al Alam D, El Agha E, Sakurai R, Kheirollahi V, Moiseenko A, Danopoulos S, Shrestha A, Schmoldt C, Quantius J, Herold S, Chao CM, Tiozzo C, De Langhe S, Plikus MV, Thornton M, Grubbs B, Minoo P, Rehan VK, Bellusci S, Evidence for the involvement of fibroblast growth factor 10 in lipofibroblast formation during embryonic lung development. Development. 2015 Dec 01;142(23):4139-50 |
1 | J:316977 Endale M, Ahlfeld S, Bao E, Chen X, Green J, Bess Z, Weirauch MT, Xu Y, Perl AK, Temporal, spatial, and phenotypical changes of PDGFRalpha expressing fibroblasts during late lung development. Dev Biol. 2017 May 15;425(2):161-175 |
2 | J:107381 Nadra K, Anghel SI, Joye E, Tan NS, Basu-Modak S, Trono D, Wahli W, Desvergne B, Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta. Mol Cell Biol. 2006 Apr;26(8):3266-81 |
2* | J:236180 Zhou H, Black SM, Benson TW, Weintraub NL, Chen W, Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is Not Required for Brown Adipogenesis but Regulates Brown Adipose Tissue Development and Function. Mol Cell Biol. 2016 Aug 1;36(15):2027-38 |
Plin5 perilipin 5 (Synonyms: 2310076L09Rik, Lsdp5, MLDP) | |
Results | Reference |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
Plk1 polo like kinase 1 (Synonyms: Plk, STPK13) | |
Results | Reference |
1* | J:314146 Gao W, Zhang Y, Luo H, Niu M, Zheng X, Hu W, Cui J, Xue X, Bo Y, Dai F, Lu Y, Yang D, Guo Y, Guo H, Li H, Zhang Y, Yang T, Li L, Zhang L, Hou R, Wen S, An C, Ma T, Jin L, Xu W, Wu Y, Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis. Cell Death Dis. 2020 Oct 26;11(10):919 |
1 | J:183605 Sakai D, Dixon J, Dixon MJ, Trainor PA, Mammalian neurogenesis requires Treacle-Plk1 for precise control of spindle orientation, mitotic progression, and maintenance of neural progenitor cells. PLoS Genet. 2012 Mar;8(3):e1002566 |
1 | J:235197 Wachowicz P, Fernandez-Miranda G, Marugan C, Escobar B, de Carcer G, Genetic depletion of Polo-like kinase 1 leads to embryonic lethality due to mitotic aberrancies. Bioessays. 2016 Jul;38 Suppl 1:S96-S106 |
Plk3 polo like kinase 3 (Synonyms: Cnk) | |
Results | Reference |
1 | J:249145 Goetz JJ, Laboissonniere LA, Wester AK, Lynch MR, Trimarchi JM, Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression. PLoS One. 2016;11(3):e0150878 |
Plp1 proteolipid protein (myelin) 1 (Synonyms: DM20, Plp) | |
Results | Reference |
3 | J:37591 Dickinson PJ, Fanarraga ML, Griffiths IR, Barrie JM, Kyriakides E, Montague P, Oligodendrocyte progenitors in the embryonic spinal cord express DM-20. Neuropathol Appl Neurobiol. 1996 Jun;22(3):188-98 |
1* | J:119850 Oh S, Huang X, Chiang C, Specific requirements of sonic hedgehog signaling during oligodendrocyte development. Dev Dyn. 2005 Nov;234(3):489-96 |
1 | J:305247 Paredes I, Vieira JR, Shah B, Ramunno CF, Dyckow J, Adler H, Richter M, Schermann G, Giannakouri E, Schirmer L, Augustin HG, Ruiz de Almodovar C, Oligodendrocyte precursor cell specification is regulated by bidirectional neural progenitor-endothelial cell crosstalk. Nat Neurosci. 2021 Apr;24(4):478-488 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1* | J:84432 Qi Y, Tan M, Hui CC, Qiu M, Gli2 is required for normal Shh signaling and oligodendrocyte development in the spinal cord. Mol Cell Neurosci. 2003 Jul;23(3):440-50 |
1 | J:74258 Stolt CC, Rehberg S, Ader M, Lommes P, Riethmacher D, Schachner M, Bartsch U, Wegner M, Terminal differentiation of myelin-forming oligodendrocytes depends on the transcription factor Sox10. Genes Dev. 2002 Jan 15;16(2):165-70 |
1 | J:107228 Sun T, Hafler BP, Kaing S, Kitada M, Ligon KL, Widlund HR, Yuk DI, Stiles CD, Rowitch DH, Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube. Dev Biol. 2006 Apr 1;292(1):152-64 |
1* | J:337458 Waldhauser V, Baroti T, Frob F, Wegner M, PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12) |
1* | J:288669 Wedel M, Frob F, Elsesser O, Wittmann MT, Lie DC, Reis A, Wegner M, Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation. Nucleic Acids Res. 2020 May 21;48(9):4839-4857 |
1 | J:152576 Ye F, Chen Y, Hoang T, Montgomery RL, Zhao XH, Bu H, Hu T, Taketo MM, van Es JH, Clevers H, Hsieh J, Bassel-Duby R, Olson EN, Lu QR, HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci. 2009 Jul;12(7):829-38 |
1 | J:208340 Zhu Q, Zhao X, Zheng K, Li H, Huang H, Zhang Z, Mastracci T, Wegner M, Chen Y, Sussel L, Qiu M, Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS. Development. 2014 Feb;141(3):548-55 |
Plpp3 phospholipid phosphatase 3 (Synonyms: 1110003O22Rik, D4Bwg0538e, D4Bwg1535e, Lpp3, Ppap2b) | |
Results | Reference |
1* | J:142493 Escalante-Alcalde D, Morales SL, Stewart CL, Generation of a reporter-null allele of Ppap2b/Lpp3 and its expression during embryogenesis. Int J Dev Biol. 2009;53(1):139-147 |
Plppr1 phospholipid phosphatase related 1 (Synonyms: E130309F12Rik, Lppr1, PRG-3) | |
Results | Reference |
1* | J:106347 Wang WZ, Molnar Z, Dynamic pattern of mRNA expression of plasticity-related gene-3 (PRG-3) in the mouse cerebral cortex during development. Brain Res Bull. 2005 Sep 15;66(4-6):454-60 |
Plppr4 phospholipid phosphatase related 4 (Synonyms: D3Bwg0562e, Lppr4, mKIAA0455, PRG-1) | |
Results | Reference |
1* | J:147117 Cheng TW, Gong Q, Secreted TARSH regulates olfactory mitral cell dendritic complexity. Eur J Neurosci. 2009 Mar;29(6):1083-95 |
Plrg1 pleiotropic regulator 1 (Synonyms: Tango4) | |
Results | Reference |
1* | J:149153 Kleinridders A, Pogoda HM, Irlenbusch S, Smyth N, Koncz C, Hammerschmidt M, Bruning JC, PLRG1 is an essential regulator of cell proliferation and apoptosis during vertebrate development and tissue homeostasis. Mol Cell Biol. 2009 Jun;29(11):3173-85 |
Pls1 plastin 1 (I-isoform) (Synonyms: I-fimbrin) | |
Results | Reference |
1* | J:26070 Chafel MM, Shen W, Matsudaira P, Sequential expression and differential localization of I-, L-, and T-fimbrin during differentiation of the mouse intestine and yolk sac. Dev Dyn. 1995 Jun;203(2):141-51 |
1 | J:306063 Morandell J, Schwarz LA, Basilico B, Tasciyan S, Dimchev G, Nicolas A, Sommer C, Kreuzinger C, Dotter CP, Knaus LS, Dobler Z, Cacci E, Schur FKM, Danzl JG, Novarino G, Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development. Nat Commun. 2021 May 24;12(1):3058 |
Pls3 plastin 3 (T-isoform) (Synonyms: T-fimbrin) | |
Results | Reference |
1* | J:26070 Chafel MM, Shen W, Matsudaira P, Sequential expression and differential localization of I-, L-, and T-fimbrin during differentiation of the mouse intestine and yolk sac. Dev Dyn. 1995 Jun;203(2):141-51 |
2 | J:306063 Morandell J, Schwarz LA, Basilico B, Tasciyan S, Dimchev G, Nicolas A, Sommer C, Kreuzinger C, Dotter CP, Knaus LS, Dobler Z, Cacci E, Schur FKM, Danzl JG, Novarino G, Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development. Nat Commun. 2021 May 24;12(1):3058 |
Pltp phospholipid transfer protein (Synonyms: Bpife, OD107) | |
Results | Reference |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
Plvap plasmalemma vesicle associated protein (Synonyms: MECA32, PV-1) | |
Results | Reference |
1 | J:284215 Auvinen K, Lokka E, Mokkala E, Jappinen N, Tyystjarvi S, Saine H, Peurla M, Shetty S, Elima K, Rantakari P, Salmi M, Fenestral diaphragms and PLVAP associations in liver sinusoidal endothelial cells are developmentally regulated. Sci Rep. 2019 Oct 30;9(1):15698 |
1 | J:253618 Bonney S, Siegenthaler JA, Differential Effects of Retinoic Acid Concentrations in Regulating Blood-Brain Barrier Properties. eNeuro. 2017 May-Jun;4(3):ENEURO.0378-16.2017 |
1 | J:24500 Hallmann R, Mayer DN, Berg EL, Broermann R, Butcher EC, Novel mouse endothelial cell surface marker is suppressed during differentiation of the blood brain barrier. Dev Dyn. 1995 Apr;202(4):325-32 |
1* | J:203907 Herrnberger L, Seitz R, Kuespert S, Bosl MR, Fuchshofer R, Tamm ER, Lack of endothelial diaphragms in fenestrae and caveolae of mutant Plvap-deficient mice. Histochem Cell Biol. 2012 Nov;138(5):709-24 |
1 | J:294228 Kalailingam P, Wang KQ, Toh XR, Nguyen TQ, Chandrakanthan M, Hasan Z, Habib C, Schif A, Radio FC, Dallapiccola B, Weiss K, Nguyen LN, Deficiency of MFSD7c results in microcephaly-associated vasculopathy in Fowler syndrome. J Clin Invest. 2020 Aug 3;130(8):4081-4093 |
2 | J:239420 Rantakari P, Jappinen N, Lokka E, Mokkala E, Gerke H, Peuhu E, Ivaska J, Elima K, Auvinen K, Salmi M, Fetal liver endothelium regulates the seeding of tissue-resident macrophages. Nature. 2016 Oct 20;538(7625):392-396 |
1* | J:341715 Sui Y, Kou S, Ge K, Cao J, Liu C, Zhang H, Expression analysis of plvap in mouse heart development, homeostasis and injury. Gene Expr Patterns. 2023 Sep 28;50:119343 |
1 | J:137812 Vondenhoff MF, Desanti GE, Cupedo T, Bertrand JY, Cumano A, Kraal G, Mebius RE, Golub R, Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner. J Leukoc Biol. 2008 Jul;84(1):152-61 |
1 | J:150308 Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009 May 1;182(9):5439-45 |
1 | J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34 |
1 | J:172737 Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RA, Peterson AS, Solloway MJ, Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol. 2011 May 30;193(5):935-51 |
Plxdc1 plexin domain containing 1 (Synonyms: 2410003I07Rik, Tem7) | |
Results | Reference |
1* | J:119921 Miller SF, Summerhurst K, Runker AE, Kerjan G, Friedel RH, Chedotal A, Murphy P, Mitchell KJ, Expression of Plxdc2/TEM7R in the developing nervous system of the mouse. Gene Expr Patterns. 2007 Apr;7(5):635-44 |
Plxna1 plexin A1 (Synonyms: 2600013D04Rik, NOV, PlexA1, Plxn1) | |
Results | Reference |
2 | J:278733 Hossain MM, Tsuzuki T, Sakakibara K, Imaizumi F, Ikegaya A, Inagaki M, Takahashi I, Ito T, Takamatsu H, Kumanogoh A, Negishi T, Yukawa K, PlexinA1 is crucial for the midline crossing of callosal axons during corpus callosum development in BALB/cAJ mice. PLoS One. 2019;14(8):e0221440 |
1 | J:279215 Jung JS, Zhang KD, Wang Z, McMurray M, Tkaczuk A, Ogawa Y, Hertzano R, Coate TM, Semaphorin-5B Controls Spiral Ganglion Neuron Branch Refinement during Development. J Neurosci. 2019 Aug 14;39(33):6425-6438 |
1* | J:167053 Ko JA, Mizuno Y, Yanai R, Chikama T, Sonoda KH, Expression of semaphorin 3A and its receptors during mouse corneal development. Biochem Biophys Res Commun. 2010 Dec 17;403(3-4):305-9 |
2* | J:67768 Murakami Y, Suto F, Shimizu M, Shinoda T, Kameyama T, Fujisawa H, Differential expression of plexin-a subfamily members in the mouse nervous system. Dev Dyn. 2001 Mar;220(3):246-58 |
1 | J:206997 Ruediger T, Zimmer G, Barchmann S, Castellani V, Bagnard D, Bolz J, Integration of opposing semaphorin guidance cues in cortical axons. Cereb Cortex. 2013 Mar;23(3):604-14 |
1* | J:226501 Uchida Y, James JM, Suto F, Mukouyama YS, Class 3 semaphorins negatively regulate dermal lymphatic network formation. Biol Open. 2015;4(9):1194-205 |
1* | J:100595 van der Zwaag B, Burbach JP, Brunner HG, van Bokhoven H, Padberg GW, Nucleotide variation analysis does not support a causal role for plexin-A1 in hereditary congenital facial paresis. Brain Res Dev Brain Res. 2005 Aug 8;158(1-2):66-71 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Plxna2 plexin A2 (Synonyms: 2810428A13Rik, mKIAA0463, OCT, PlexA2, Plxn2) | |
Results | Reference |
1 | J:320518 Belle M, Parray A, Belle M, Chedotal A, Nguyen-Ba-Charvet KT, PlexinA2 and Sema6A are required for retinal progenitor cell migration. Dev Growth Differ. 2016 Jun;58(5):492-502 |
1* | J:67768 Murakami Y, Suto F, Shimizu M, Shinoda T, Kameyama T, Fujisawa H, Differential expression of plexin-a subfamily members in the mouse nervous system. Dev Dyn. 2001 Mar;220(3):246-58 |
1 | J:206997 Ruediger T, Zimmer G, Barchmann S, Castellani V, Bagnard D, Bolz J, Integration of opposing semaphorin guidance cues in cortical axons. Cereb Cortex. 2013 Mar;23(3):604-14 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Plxna3 plexin A3 (Synonyms: PlexA3, Plxa3, Plxn3, Plxn4, SEX) | |
Results | Reference |
1* | J:72426 Cheng HJ, Bagri A, Yaron A, Stein E, Pleasure SJ, Tessier-Lavigne M, Plexin-a3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections. Neuron. 2001 Oct 25;32(2):249-63 |
2 | J:226819 Coate TM, Spita NA, Zhang KD, Isgrig KT, Kelley MW, Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife. 2015;4 |
1 | J:279215 Jung JS, Zhang KD, Wang Z, McMurray M, Tkaczuk A, Ogawa Y, Hertzano R, Coate TM, Semaphorin-5B Controls Spiral Ganglion Neuron Branch Refinement during Development. J Neurosci. 2019 Aug 14;39(33):6425-6438 |
1 | J:35300 Maestrini E, Tamagnone L, Longati P, Cremona O, Gulisano M, Bione S, Tamanini F, Neel BG, Toniolo D, Comoglio PM, A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor. Proc Natl Acad Sci U S A. 1996 Jan 23;93(2):674-8 |
1* | J:67768 Murakami Y, Suto F, Shimizu M, Shinoda T, Kameyama T, Fujisawa H, Differential expression of plexin-a subfamily members in the mouse nervous system. Dev Dyn. 2001 Mar;220(3):246-58 |
1 | J:206997 Ruediger T, Zimmer G, Barchmann S, Castellani V, Bagnard D, Bolz J, Integration of opposing semaphorin guidance cues in cortical axons. Cereb Cortex. 2013 Mar;23(3):604-14 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:167943 Takeuchi H, Inokuchi K, Aoki M, Suto F, Tsuboi A, Matsuda I, Suzuki M, Aiba A, Serizawa S, Yoshihara Y, Fujisawa H, Sakano H, Sequential arrival and graded secretion of Sema3F by olfactory neuron axons specify map topography at the bulb. Cell. 2010 Jun 11;141(6):1056-67 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Plxna4 plexin A4 (Synonyms: Plxa4) | |
Results | Reference |
1 | J:238795 Paap RH, Oosterbroek S, Wagemans CM, von Oerthel L, Schellevis RD, Vastenhouw-van der Linden AJ, Groot Koerkamp MJ, Hoekman MF, Smidt MP, FoxO6 affects Plxna4-mediated neuronal migration during mouse cortical development. Proc Natl Acad Sci U S A. 2016 Oct 24; |
1 | J:206997 Ruediger T, Zimmer G, Barchmann S, Castellani V, Bagnard D, Bolz J, Integration of opposing semaphorin guidance cues in cortical axons. Cereb Cortex. 2013 Mar;23(3):604-14 |
2* | J:82114 Suto F, Murakami Y, Nakamura F, Goshima Y, Fujisawa H, Identification and characterization of a novel mouse plexin, plexin-A4. Mech Dev. 2003 Mar;120(3):385-96 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Plxnb1 plexin B1 (Synonyms: 2900002G15Rik, mKIAA0407) | |
Results | Reference |
1* | J:225235 Azzarelli R, Pacary E, Garg R, Garcez P, van den Berg D, Riou P, Ridley AJ, Friedel RH, Parsons M, Guillemot F, An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration. Nat Commun. 2014;5:3405 |
1 | J:304850 Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernandez-Baldovinos J, Zhou L, Hoss C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Grone HJ, Graumann PL, Niessen CM, Offermanns S, Wickstrom SA, Worzfeld T, Mechanochemical control of epidermal stem cell divisions by B-plexins. Nat Commun. 2021 Feb 26;12(1):1308 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Plxnb2 plexin B2 (Synonyms: 1110007H23Rik, Debt, mKIAA0315) | |
Results | Reference |
1* | J:225235 Azzarelli R, Pacary E, Garg R, Garcez P, van den Berg D, Riou P, Ridley AJ, Friedel RH, Parsons M, Guillemot F, An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration. Nat Commun. 2014;5:3405 |
1 | J:297714 Brignani S, Raj DDA, Schmidt ERE, Dudukcu O, Adolfs Y, De Ruiter AA, Rybiczka-Tesulov M, Verhagen MG, van der Meer C, Broekhoven MH, Moreno-Bravo JA, Grossouw LM, Dumontier E, Cloutier JF, Chedotal A, Pasterkamp RJ, Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development. Neuron. 2020 Aug 19;107(4):684-702.e9 |
1 | J:304850 Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernandez-Baldovinos J, Zhou L, Hoss C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Grone HJ, Graumann PL, Niessen CM, Offermanns S, Wickstrom SA, Worzfeld T, Mechanochemical control of epidermal stem cell divisions by B-plexins. Nat Commun. 2021 Feb 26;12(1):1308 |
1 | J:168399 Perala N, Jakobson M, Ola R, Fazzari P, Penachioni JY, Nymark M, Tanninen T, Immonen T, Tamagnone L, Sariola H, Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney. Differentiation. 2011 Feb;81(2):81-91 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Plxnb3 plexin B3 (Synonyms: Plxn6) | |
Results | Reference |
1* | J:225235 Azzarelli R, Pacary E, Garg R, Garcez P, van den Berg D, Riou P, Ridley AJ, Friedel RH, Parsons M, Guillemot F, An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration. Nat Commun. 2014;5:3405 |
Plxnc1 plexin C1 (Synonyms: 2510048K12Rik, CD232, vespr) | |
Results | Reference |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Plxnd1 plexin D1 (Synonyms: 6230425C21Rik, b2b1863Clo, b2b553Clo) | |
Results | Reference |
1 | J:197849 Deck M, Lokmane L, Chauvet S, Mailhes C, Keita M, Niquille M, Yoshida M, Yoshida Y, Lebrand C, Mann F, Grove EA, Garel S, Pathfinding of corticothalamic axons relies on a rendezvous with thalamic projections. Neuron. 2013 Feb 6;77(3):472-84 |
2 | J:349009 Kim N, Li Y, Yu R, Kwon HS, Song A, Jun MH, Jeong JY, Lee JH, Lim HH, Kim MJ, Kim JW, Oh WJ, Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1. Elife. 2024 Mar 25;13 |
1 | J:306872 Maruyama K, Naemura K, Arima Y, Uchijima Y, Nagao H, Yoshihara K, Singh MK, Uemura A, Matsuzaki F, Yoshida Y, Kurihara Y, Miyagawa-Tomita S, Kurihara H, Semaphorin3E-PlexinD1 signaling in coronary artery and lymphatic vessel development with clinical implications in myocardial recovery. iScience. 2021 Apr 23;24(4):102305 |
1 | J:260018 Mata A, Gil V, Perez-Clausell J, Dasilva M, Gonzalez-Calixto MC, Soriano E, Garcia-Verdugo JM, Sanchez-Vives MV, Del Rio JA, New functions of Semaphorin 3E and its receptor PlexinD1 during developing and adult hippocampal formation. Sci Rep. 2018 Jan 22;8(1):1381 |
1 | J:207212 Oh WJ, Gu C, Establishment of neurovascular congruency in the mouse whisker system by an independent patterning mechanism. Neuron. 2013 Oct 16;80(2):458-69 |
1 | J:149553 Pecho-Vrieseling E, Sigrist M, Yoshida Y, Jessell TM, Arber S, Specificity of sensory-motor connections encoded by Sema3e-Plxnd1 recognition. Nature. 2009 Jun 11;459(7248):842-6 |
1* | J:80128 van der Zwaag B, Hellemons AJ, Leenders WP, Burbach JP, Brunner HG, Padberg GW, Van Bokhoven H, PLEXIN-D1, a novel plexin family member, is expressed in vascular endothelium and the central nervous system during mouse embryogenesis. Dev Dyn. 2002 Nov;225(3):336-43 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
1 | J:143763 Zhang Y, Singh MK, Degenhardt KR, Lu MM, Bennett J, Yoshida Y, Epstein JA, Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects. Dev Biol. 2009 Jan 1;325(1):82-93 |
Pmaip1 phorbol-12-myristate-13-acetate-induced protein 1 (Synonyms: Noxa) | |
Results | Reference |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
1 | J:261834 Maskell LJ, Qamar K, Babakr AA, Hawkins TA, Heads RJ, Budhram-Mahadeo VS, Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart. Cell Death Dis. 2017 Jun 8;8(6):e2861 |
Pml promyelocytic leukemia (Synonyms: 1200009E24Rik, Trim19) | |
Results | Reference |
1 | J:306221 Chiang SY, Wu HC, Lin SY, Chen HY, Wang CF, Yeh NH, Shih JH, Huang YS, Kuo HC, Chou SJ, Chen RH, Usp11 controls cortical neurogenesis and neuronal migration through Sox11 stabilization. Sci Adv. 2021 Feb;7(7) |
1* | J:347585 Leon NY, Le TNU, Garvie A, Wong LH, Bagheri-Fam S, Harley VR, Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. iScience. 2024 May 17;27(5):109629 |
Pmp22 peripheral myelin protein 22 (Synonyms: Gas-3, TRE002) | |
Results | Reference |
1* | J:30616 Baechner D, Liehr T, Hameister H, Altenberger H, Grehl H, Suter U, Rautenstrauss B, Widespread expression of the peripheral myelin protein-22 gene (PMP22) in neural and non-neural tissues during murine development. J Neurosci Res. 1995 Dec 15;42(6):733-41 |
1 | J:288683 Gacem N, Kavo A, Zerad L, Richard L, Mathis S, Kapur RP, Parisot M, Amiel J, Dufour S, de la Grange P, Pingault V, Vallat JM, Bondurand N, ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. Nat Commun. 2020 Jan 10;11(1):198 |
Pnmt phenylethanolamine-N-methyltransferase (Synonyms: Pent) | |
Results | Reference |
1* | J:296652 Chan WH, Gonsalvez DG, Young HM, Southard-Smith EM, Cane KN, Anderson CR, Differences in CART expression and cell cycle behavior discriminate sympathetic neuroblast from chromaffin cell lineages in mouse sympathoadrenal cells. Dev Neurobiol. 2016 Feb;76(2):137-49 |
1 | J:191801 Huang CC, Shih MC, Hsu NC, Chien Y, Chung BC, Fetal glucocorticoid synthesis is required for development of fetal adrenal medulla and hypothalamus feedback suppression. Endocrinology. 2012 Oct;153(10):4749-56 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
1 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
Pnn pinin (Synonyms: D12Ertd512e) | |
Results | Reference |
1 | J:164807 Joo JH, Taxter TJ, Munguba GC, Kim YH, Dhaduvai K, Dunn NW, Degan WJ, Oh SP, Sugrue SP, Pinin modulates expression of an intestinal homeobox gene, Cdx2, and plays an essential role for small intestinal morphogenesis. Dev Biol. 2010 Sep 15;345(2):191-203 |
4* | J:109158 Leu S, Ouyang P, Spatial and temporal expression profile of pinin during mouse development. Gene Expr Patterns. 2006 Aug;6(6):620-31 |
Pnoc prepronociceptin (Synonyms: N23K, N/OFQ, Npnc1, OFQ/N, proorphanin) | |
Results | Reference |
1 | J:142008 Huang M, Huang T, Xiang Y, Xie Z, Chen Y, Yan R, Xu J, Cheng L, Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons. Dev Biol. 2008 Jul 2;322(2):394-405 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
Pnpla2 patatin-like phospholipase domain containing 2 (Synonyms: 0610039C21Rik, 1110001C14Rik, Atgl, desnutrin) | |
Results | Reference |
1* | J:236180 Zhou H, Black SM, Benson TW, Weintraub NL, Chen W, Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is Not Required for Brown Adipogenesis but Regulates Brown Adipose Tissue Development and Function. Mol Cell Biol. 2016 Aug 1;36(15):2027-38 |
Pnpla6 patatin-like phospholipase domain containing 6 (Synonyms: MSws, Nte, Swiss-cheese) | |
Results | Reference |
1* | J:87675 Moser M, Li Y, Vaupel K, Kretzschmar D, Kluge R, Glynn P, Buettner R, Placental failure and impaired vasculogenesis result in embryonic lethality for neuropathy target esterase-deficient mice. Mol Cell Biol. 2004 Feb;24(4):1667-79 |
Podxl podocalyxin-like (Synonyms: Ly102, PC, Pclp1, podocalyxin, Podxl1) | |
Results | Reference |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:239651 Hurtado R, Zewdu R, Mtui J, Liang C, Aho R, Kurylo C, Selleri L, Herzlinger D, Pbx1-dependent control of VMC differentiation kinetics underlies gross renal vascular patterning. Development. 2015 Aug 01;142(15):2653-64 |
1 | J:161574 Onitsuka I, Tanaka M, Miyajima A, Characterization and functional analyses of hepatic mesothelial cells in mouse liver development. Gastroenterology. 2010 Apr;138(4):1525-35, 1535.e1-6 |
1 | J:308707 Paulson D, Harms R, Ward C, Latterell M, Pazour GJ, Fink DM, Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation. Front Cell Dev Biol. 2021;9:672625 |
1 | J:181330 Sabine A, Agalarov Y, Maby-El Hajjami H, Jaquet M, Hagerling R, Pollmann C, Bebber D, Pfenniger A, Miura N, Dormond O, Calmes JM, Adams RH, Makinen T, Kiefer F, Kwak BR, Petrova TV, Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation. Dev Cell. 2012 Feb 14;22(2):430-45 |
2 | J:346405 Vitureira N, Andres R, Perez-Martinez E, Martinez A, Bribian A, Blasi J, Chelliah S, Lopez-Domenech G, De Castro F, Burgaya F, McNagny K, Soriano E, Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation. PLoS One. 2010 Aug 10;5(8):e12003 |
1 | J:306543 Yu Z, Zeng J, Wang J, Cui Y, Song X, Zhang Y, Cheng X, Hou N, Teng Y, Lan Y, Chen Y, Yang X, Hepatocyte growth factor-regulated tyrosine kinase substrate is essential for endothelial cell polarity and cerebrovascular stability. Cardiovasc Res. 2021 Jan 21;117(2):533-546 |
Podxl2 podocalyxin-like 2 (Synonyms: D130074J02Rik, Endoglycan, PODLX2) | |
Results | Reference |
1* | J:99372 van der Zwaag B, Burbach JP, Scharfe C, Oefner PJ, Brunner HG, Padberg GW, van Bokhoven H, Identifying new candidate genes for hereditary facial paresis on chromosome 3q21-q22 by RNA in situ hybridization in mouse. Genomics. 2005 Jul;86(1):55-67 |
Pof1b premature ovarian failure 1B (Synonyms: 2310066B14Rik) | |
Results | Reference |
2* | J:117822 Rizzolio F, Bione S, Villa A, Berti E, Cassetti A, Bulfone A, Tribioli C, Toniolo D, Spatial and temporal expression of POF1B, a gene expressed in epithelia. Gene Expr Patterns. 2007 Feb;7(4):529-34 |
Pofut1 protein O-fucosyltransferase 1 (Synonyms: O-FucT-1) | |
Results | Reference |
1 | J:83299 Shi S, Stanley P, Protein O-fucosyltransferase 1 is an essential component of Notch signaling pathways. Proc Natl Acad Sci U S A. 2003 Apr 29;100(9):5234-9 |
2 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
Pogz pogo transposable element with ZNF domain (Synonyms: 9530006B08Rik) | |
Results | Reference |
2 | J:286398 Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, Furuse T, Shibuya H, Yasuda Y, Yamamori H, Fujimoto M, Nagayasu K, Yamamoto K, Kitagawa K, Miura H, Gotoda-Nishimura N, Igarashi H, Hayashida M, Baba M, Kondo M, Hasebe S, Ueshima K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Iguchi T, Sato M, Yamaguchi S, Tamura M, Wakana S, Yoshiki A, Watabe AM, Okano H, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T, Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes. Nat Commun. 2020 Feb 26;11(1):859 |
Polr2a polymerase (RNA) II (DNA directed) polypeptide A (Synonyms: 220kDa, Rpo2-1) | |
Results | Reference |
1 | J:190424 Kraemer N, Neubert G, Issa L, Ninnemann O, Seiler AE, Kaindl AM, Reference genes in the developing murine brain and in differentiating embryonic stem cells. Neurol Res. 2012 Sep;34(7):664-8 |
1 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
1 | J:172282 Zhou ZQ, Shung CY, Ota S, Akiyama H, Keene DR, Hurlin PJ, Sequential and coordinated actions of c-Myc and N-Myc control appendicular skeletal development. PLoS One. 2011;6(4):e18795 |
Pomc pro-opiomelanocortin-alpha (Synonyms: ACTH, adrenal corticotropic hormone, alpha-melanocyte stimulating hormone, alpha-MSH, alphaMSH, BE, beta-endorphin, beta-melanocyte stimulating hormone, beta-MSH, gamma-melanocyte stimulating hormone, gamma-MSH, POMC, Pomc-1) | |
Results | Reference |
1 | J:223814 Aujla PK, Bogdanovic V, Naratadam GT, Raetzman LT, Persistent expression of activated notch in the developing hypothalamus affects survival of pituitary progenitors and alters pituitary structure. Dev Dyn. 2015 Aug;244(8):921-34 |
1* | J:290740 Brachet C, Kozhemyakina EA, Boros E, Heinrichs C, Balikova I, Soblet J, Smits G, Vilain C, Mathers PH, Truncating RAX Mutations: Anophthalmia, Hypopituitarism, Diabetes Insipidus, and Cleft Palate in Mice and Men. J Clin Endocrinol Metab. 2019 Jul 1;104(7):2925-2930 |
1 | J:188254 Budry L, Balsalobre A, Gauthier Y, Khetchoumian K, L'honore A, Vallette S, Brue T, Figarella-Branger D, Meij B, Drouin J, The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling. Genes Dev. 2012 Oct 15;26(20):2299-310 |
1 | J:264143 Cheung L, Le Tissier P, Goldsmith SG, Treier M, Lovell-Badge R, Rizzoti K, NOTCH activity differentially affects alternative cell fate acquisition and maintenance. Elife. 2018 Mar 26;7:e33318 |
1* | J:73085 Dasen JS, Barbera JP, Herman TS, Connell SO, Olson L, Ju B, Tollkuhn J, Baek SH, Rose DW, Rosenfeld MG, Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 1;15(23):3193-207 |
1* | J:308824 de Guia RM, Hassing AS, Ma T, Plucinska K, Holst B, Gerhart-Hines Z, Emanuelli B, Treebak JT, Ablation of Nampt in AgRP neurons leads to neurodegeneration and impairs fasting- and ghrelin-mediated food intake. FASEB J. 2021 May;35(5):e21450 |
1* | J:130185 Ellsworth BS, Butts DL, Camper SA, Mechanisms underlying pituitary hypoplasia and failed cell specification in Lhx3-deficient mice. Dev Biol. 2008 Jan 1;313(1):118-29 |
1 | J:176609 Goldberg LB, Aujla PK, Raetzman LT, Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis. Dev Biol. 2011 Oct 1;358(1):23-32 |
1 | J:235668 Goldsmith S, Lovell-Badge R, Rizzoti K, SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitary. Development. 2016 Jul 1;143(13):2376-88 |
1* | J:143548 Himes AD, Raetzman LT, Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1. Dev Biol. 2009 Jan 1;325(1):151-61 |
1* | J:19457 Japon MA, Rubinstein M, Low MJ, In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development. J Histochem Cytochem. 1994 Aug;42(8):1117-25 |
1 | J:240480 Kapali J, Kabat BE, Schmidt KL, Stallings CE, Tippy M, Jung DO, Edwards BS, Nantie LB, Raeztman LT, Navratil AM, Ellsworth BS, Foxo1 Is Required for Normal Somatotrope Differentiation. Endocrinology. 2016 Nov;157(11):4351-4363 |
1 | J:89087 Lamolet B, Poulin G, Chu K, Guillemot F, Tsai MJ, Drouin J, Tpit-independent function of NeuroD1(BETA2) in pituitary corticotroph differentiation. Mol Endocrinol. 2004 Apr;18(4):995-1003 |
1* | J:228711 Lanctot C, Gauthier Y, Drouin J, Pituitary homeobox 1 (Ptx1) is differentially expressed during pituitary development. Endocrinology. 1999 Mar;140(3):1416-22 |
1 | J:332513 Laporte E, De Vriendt S, Hoekx J, Vankelecom H, Interleukin-6 is dispensable in pituitary normal development and homeostasis but needed for pituitary stem cell activation following local injury. Front Endocrinol (Lausanne). 2022;13:1092063 |
1* | J:136893 Lavoie PL, Budry L, Balsalobre A, Drouin J, Developmental Dependence on NurRE and EboxNeuro for Expression of Pituitary Proopiomelanocortin. Mol Endocrinol. 2008 Jul;22(7):1647-57 |
1 | J:263715 Lee B, Kim J, An T, Kim S, Patel EM, Raber J, Lee SK, Lee S, Lee JW, Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons. Nat Commun. 2018 May 23;9(1):2026 |
1 | J:237344 Lee B, Lee S, Lee SK, Lee JW, The LIM-homeobox transcription factor Isl1 plays crucial roles in the development of multiple arcuate nucleus neurons. Development. 2016 Oct 15;143(20):3763-3773 |
1 | J:301300 Lee CH, Song DK, Park CB, Choi J, Kang GM, Shin SH, Kwon I, Park S, Kim S, Kim JY, Dugu H, Park JW, Choi JH, Min SH, Sohn JW, Kim MS, Primary cilia mediate early life programming of adiposity through lysosomal regulation in the developing mouse hypothalamus. Nat Commun. 2020 Nov 13;11(1):5772 |
1* | J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20 |
1 | J:82562 Pulichino AM, Vallette-Kasic S, Tsai JP, Couture C, Gauthier Y, Drouin J, Tpit determines alternate fates during pituitary cell differentiation. Genes Dev. 2003 Mar 15;17(6):738-47 |
1* | J:87368 Raetzman LT, Ross SA, Cook S, Dunwoodie SL, Camper SA, Thomas PQ, Developmental regulation of Notch signaling genes in the embryonic pituitary: Prop1 deficiency affects Notch2 expression. Dev Biol. 2004 Jan 15;265(2):329-40 |
1 | J:134188 Reichardt HM, Schutz G, Feedback control of glucocorticoid production is established during fetal development. Mol Med. 1996 Nov;2(6):735-44 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
3* | J:168512 Simard M, Cote M, Provost PR, Tremblay Y, Expression of genes related to the hypothalamic-pituitary-adrenal axis in murine fetal lungs in late gestation. Reprod Biol Endocrinol. 2010;8:134 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1* | J:62908 Venihaki M, Carrigan A, Dikkes P, Majzoub JA, Circadian rise in maternal glucocorticoid prevents pulmonary dysplasia in fetal mice with adrenal insufficiency. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7336-41 |
2* | J:353361 Yu H, Chiang A, Rubinstein M, Low MJ, The homeodomain transcription factor Six3 regulates hypothalamic Pomc expression and its absence from POMC neurons induces hyperphagia and mild obesity in male mice. Mol Metab. 2024 Sep;87:101993 |
1 | J:319845 Yu H, Rubinstein M, Low MJ, Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes. Elife. 2022 Jan 19;11:e72883 |
1 | J:112960 Zhu X, Zhang J, Tollkuhn J, Ohsawa R, Bresnick EH, Guillemot F, Kageyama R, Rosenfeld MG, Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. Genes Dev. 2006 Oct 1;20(19):2739-53 |
Pomgnt2 protein O-linked mannose beta 1,4-N-acetylglucosaminyltransferase 2 (Synonyms: C85492, Gtdc2) | |
Results | Reference |
1* | J:203678 Manzini MC, Tambunan DE, Hill RS, Yu TW, Maynard TM, Heinzen EL, Shianna KV, Stevens CR, Partlow JN, Barry BJ, Rodriguez J, Gupta VA, Al-Qudah AK, Eyaid WM, Friedman JM, Salih MA, Clark R, Moroni I, Mora M, Beggs AH, Gabriel SB, Walsh CA, Exome sequencing and functional validation in zebrafish identify GTDC2 mutations as a cause of Walker-Warburg syndrome. Am J Hum Genet. 2012 Sep 7;91(3):541-7 |
Pomk protein-O-mannose kinase (Synonyms: 4930444A02Rik, Sgk196) | |
Results | Reference |
1* | J:214732 Di Costanzo S, Balasubramanian A, Pond HL, Rozkalne A, Pantaleoni C, Saredi S, Gupta VA, Sunu CM, Yu TW, Kang PB, Salih MA, Mora M, Gussoni E, Walsh CA, Manzini MC, POMK mutations disrupt muscle development leading to a spectrum of neuromuscular presentations. Hum Mol Genet. 2014 Nov 1;23(21):5781-92 |
Pomt1 protein-O-mannosyltransferase 1 | |
Results | Reference |
1* | J:93435 Willer T, Prados B, Falcon-Perez JM, Renner-Muller I, Przemeck GK, Lommel M, Coloma A, Valero MC, de Angelis MH, Tanner W, Wolf E, Strahl S, Cruces J, Targeted disruption of the Walker-Warburg syndrome gene Pomt1 in mouse results in embryonic lethality. (Correction: 2004;101(45):16081). Proc Natl Acad Sci U S A. 2004 Oct 28;101(39):14126-31 |
Pon1 paraoxonase 1 (Synonyms: Pon) | |
Results | Reference |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
Por cytochrome p450 oxidoreductase (Synonyms: 4933424M13Rik, CPR, CYPOR, NADH cytochrome P450 oxydoreductase) | |
Results | Reference |
2* | J:58885 Keeney DS, Waterman MR, Two novel sites of expression of NADPH cytochrome P450 reductase during murine embryogenesis: limb mesenchyme and developing olfactory neuroepithelia. Dev Dyn. 1999 Dec;216(4-5):511-7 |
Porcn porcupine O-acyltransferase (Synonyms: 2410004O13Rik, DXHXS7465e, mMg61, Mporc, porc) | |
Results | Reference |
2 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
2* | J:311540 Oliver BL, Young CA, Munnamalai V, Spatial and temporal expression of PORCN is highly dynamic in the developing mouse cochlea. Gene Expr Patterns. 2021 Sep 20;42:119214 |
Postn periostin, osteoblast specific factor (Synonyms: A630052E07Rik, Osf2, OSF-2, peri, Periostin) | |
Results | Reference |
1 | J:226941 Akerberg BN, Sarangam ML, Stankunas K, Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Dev Biol. 2015 Nov 1;407(1):158-72 |
1 | J:262819 Bohnenpoll T, Feraric S, Nattkemper M, Weiss AC, Rudat C, Meuser M, Trowe MO, Kispert A, Diversification of Cell Lineages in Ureter Development. J Am Soc Nephrol. 2017 Jun;28(6):1792-1801 |
1 | J:192176 Casanova JC, Travisano S, de la Pompa JL, Epithelial-to-mesenchymal transition in epicardium is independent of snail1. Genesis. 2013 Jan;51(1):32-40 |
2* | J:166807 Fortunati D, Reppe S, Fjeldheim AK, Nielsen M, Gautvik VT, Gautvik KM, Periostin is a collagen associated bone matrix protein regulated by parathyroid hormone. Matrix Biol. 2010 Sep;29(7):594-601 |
1 | J:173586 Hahurij ND, Kolditz DP, Bokenkamp R, Markwald RR, Schalij MJ, Poelmann RE, Gittenberger-DE Groot AC, Blom NA, Accessory atrioventricular myocardial pathways in mouse heart development: substrate for supraventricular tachycardias. Pediatr Res. 2011 Jul;70(1):37-43 |
2* | J:163714 Hakuno D, Kimura N, Yoshioka M, Mukai M, Kimura T, Okada Y, Yozu R, Shukunami C, Hiraki Y, Kudo A, Ogawa S, Fukuda K, Periostin advances atherosclerotic and rheumatic cardiac valve degeneration by inducing angiogenesis and MMP production in humans and rodents. J Clin Invest. 2010 Jul 1;120(7):2292-306 |
1 | J:89225 Kruzynska-Frejtag A, Wang J, Maeda M, Rogers R, Krug E, Hoffman S, Markwald RR, Conway SJ, Periostin is expressed within the developing teeth at the sites of epithelial-mesenchymal interaction. Dev Dyn. 2004 Apr;229(4):857-68 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
1 | J:163275 Snyder EM, Small CL, Bomgardner D, Xu B, Evanoff R, Griswold MD, Hinton BT, Gene expression in the efferent ducts, epididymis, and vas deferens during embryonic development of the mouse. Dev Dyn. 2010 Sep;239(9):2479-91 |
1* | J:233043 Sonnenberg-Riethmacher E, Miehe M, Riethmacher D, Promotion of periostin expression contributes to the migration of Schwann cells. J Cell Sci. 2015 Sep 1;128(17):3345-55 |
1 | J:340973 Wojahn I, Ludtke TH, Christoffels VM, Trowe MO, Kispert A, TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung. Respir Res. 2019 Dec 23;20(1):292 |
1* | J:135261 Zhu S, Barbe MF, Amin N, Rani S, Popoff SN, Safadi FF, Litvin J, Immunolocalization of Periostin-like factor and Periostin during embryogenesis. J Histochem Cytochem. 2008 Apr;56(4):329-45 |
Pou1f1 POU domain, class 1, transcription factor 1 (Synonyms: GHF-1, Hmp1, Pit-1, Pit1, Pit1-rs1, Snell dwarf) | |
Results | Reference |
1 | J:30290 Andersen B, Pearse RV 2nd, Jenne K, Sornson M, Lin SC, Bartke A, Rosenfeld MG, The Ames dwarf gene is required for Pit-1 gene activation. Dev Biol. 1995 Dec;172(2):495-503 |
1 | J:223814 Aujla PK, Bogdanovic V, Naratadam GT, Raetzman LT, Persistent expression of activated notch in the developing hypothalamus affects survival of pituitary progenitors and alters pituitary structure. Dev Dyn. 2015 Aug;244(8):921-34 |
1 | J:41856 Bosse R, Fumagalli F, Jaber M, Giros B, Gainetdinov RR, Wetsel WC , Missale C , Caron MG, Anterior pituitary hypoplasia and dwarfism in mice lacking the dopamine transporter. Neuron. 1997 Jul;19(1):127-38 |
1* | J:290740 Brachet C, Kozhemyakina EA, Boros E, Heinrichs C, Balikova I, Soblet J, Smits G, Vilain C, Mathers PH, Truncating RAX Mutations: Anophthalmia, Hypopituitarism, Diabetes Insipidus, and Cleft Palate in Mice and Men. J Clin Endocrinol Metab. 2019 Jul 1;104(7):2925-2930 |
1 | J:233385 Castinetti F, Brinkmeier ML, Mortensen AH, Vella KR, Gergics P, Brue T, Hollenberg AN, Gan L, Camper SA, ISL1 Is Necessary for Maximal Thyrotrope Response to Hypothyroidism. Mol Endocrinol. 2015 Oct;29(10):1510-21 |
1* | J:73085 Dasen JS, Barbera JP, Herman TS, Connell SO, Olson L, Ju B, Tollkuhn J, Baek SH, Rose DW, Rosenfeld MG, Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 1;15(23):3193-207 |
1 | J:70561 Dasen JS, O'Connell SM, Flynn SE, Treier M, Gleiberman AS, Szeto DP, Hooshmand F, Aggarwal AK, Rosenfeld MG, Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types. Cell. 1999 May 28;97(5):587-98 |
1 | J:132812 Fauquier T, Rizzoti K, Dattani M, Lovell-Badge R, Robinson IC, SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2907-12 |
1 | J:241998 Haston S, Pozzi S, Carreno G, Manshaei S, Panousopoulos L, Gonzalez-Meljem JM, Apps JR, Virasami A, Thavaraj S, Gutteridge A, Forshew T, Marais R, Brandner S, Jacques TS, Andoniadou CL, Martinez-Barbera JP, MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma. Development. 2017 Jun 15;144(12):2141-2152 |
1* | J:143548 Himes AD, Raetzman LT, Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1. Dev Biol. 2009 Jan 1;325(1):151-61 |
2 | J:240480 Kapali J, Kabat BE, Schmidt KL, Stallings CE, Tippy M, Jung DO, Edwards BS, Nantie LB, Raeztman LT, Navratil AM, Ellsworth BS, Foxo1 Is Required for Normal Somatotrope Differentiation. Endocrinology. 2016 Nov;157(11):4351-4363 |
1 | J:89087 Lamolet B, Poulin G, Chu K, Guillemot F, Tsai MJ, Drouin J, Tpit-independent function of NeuroD1(BETA2) in pituitary corticotroph differentiation. Mol Endocrinol. 2004 Apr;18(4):995-1003 |
1 | J:332513 Laporte E, De Vriendt S, Hoekx J, Vankelecom H, Interleukin-6 is dispensable in pituitary normal development and homeostasis but needed for pituitary stem cell activation following local injury. Front Endocrinol (Lausanne). 2022;13:1092063 |
1* | J:33102 Lin C, Lin SC, Chang CP, Rosenfeld MG, Pit-1-dependent expression of the receptor for growth hormone releasing factor mediates pituitary cell growth [see comments]. Nature. 1992 Dec 24-31;360(6406):765-8 |
1 | J:234328 Perez Millan MI, Brinkmeier ML, Mortensen AH, Camper SA, PROP1 triggers epithelial-mesenchymal transition-like process in pituitary stem cells. Elife. 2016;5:e14470 |
1* | J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20 |
1* | J:122509 Raetzman LT, Cai JX, Camper SA, Hes1 is required for pituitary growth and melanotrope specification. Dev Biol. 2007 Apr 15;304(2):455-66 |
1 | J:108374 Vesper AH, Raetzman LT, Camper SA, Role of prophet of Pit1 (PROP1) in gonadotrope differentiation and puberty. Endocrinology. 2006 Apr;147(4):1654-63 |
1 | J:112960 Zhu X, Zhang J, Tollkuhn J, Ohsawa R, Bresnick EH, Guillemot F, Kageyama R, Rosenfeld MG, Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. Genes Dev. 2006 Oct 1;20(19):2739-53 |
Pou2f2 POU domain, class 2, transcription factor 2 (Synonyms: Oct-2, Oct2a, Oct2b, Oct2c, Oct2d, Otf-2, Otf2) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Pou2f3 POU domain, class 2, transcription factor 3 (Synonyms: Epoc-1, Oct11, Oct-11a, Otf-11, Otf11, Skin, Skin-1a, Skn-1a, Skn-li) | |
Results | Reference |
1 | J:226215 Yamaguchi T, Yamashita J, Ohmoto M, Aoude I, Ogura T, Luo W, Bachmanov AA, Lin W, Matsumoto I, Hirota J, Skn-1a/Pou2f3 is required for the generation of Trpm5-expressing microvillous cells in the mouse main olfactory epithelium. BMC Neurosci. 2014;15:13 |
Pou3f1 POU domain, class 3, transcription factor 1 (Synonyms: Oct-6, Oct6, Otf6, Scip, Test1, Tst-1, Tst1) | |
Results | Reference |
1* | J:348861 Aberle T, Walter A, Piefke S, Hillgartner S, Wust HM, Wegner M, Kuspert M, Sox10 Activity and the Timing of Schwann Cell Differentiation Are Controlled by a Tle4-Dependent Negative Feedback Loop. Int J Mol Sci. 2024 May 11;25(10) |
1 | J:249229 Espinosa-Medina I, Outin E, Picard CA, Chettouh Z, Dymecki S, Consalez GG, Coppola E, Brunet JF, Neurodevelopment. Parasympathetic ganglia derive from Schwann cell precursors. Science. 2014 Jul 4;345(6192):87-90 |
1 | J:162692 Finzsch M, Schreiner S, Kichko T, Reeh P, Tamm ER, Bosl MR, Meijer D, Wegner M, Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage. J Cell Biol. 2010 May 17;189(4):701-12 |
1 | J:96824 Friedrich RP, Schlierf B, Tamm ER, Bosl MR, Wegner M, The class III POU domain protein Brn-1 can fully replace the related Oct-6 during schwann cell development and myelination. Mol Cell Biol. 2005 Mar;25(5):1821-9 |
1* | J:339296 Fries M, Brown TW, Jolicoeur C, Boulan B, Boudreau-Pinsonneault C, Javed A, Abram P, Cayouette M, Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections. Cell Rep. 2023 Aug 16;42(8):112985 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:59284 Galceran J, Miyashita-Lin EM, Devaney E, Rubenstein JL, Grosschedl R, Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1. Development. 2000 Feb;127(3):469-82 |
1 | J:44591 Garel S, Marin F, Grosschedl R, Charnay P, Ebf1 controls early cell differentiation in the embryonic striatum. Development. 1999 Dec;126(23):5285-94 |
1 | J:134970 Inoue T, Ogawa M, Mikoshiba K, Aruga J, Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly. J Neurosci. 2008 Apr 30;28(18):4712-25 |
1* | J:91057 Louvi A, Sisodia SS, Grove EA, Presenilin 1 in migration and morphogenesis in the central nervous system. Development. 2004 Jul;131(13):3093-105 |
1* | J:98542 Rowan S, Cepko CL, A POU factor binding site upstream of the Chx10 homeobox gene is required for Chx10 expression in subsets of retinal progenitor cells and bipolar cells. Dev Biol. 2005 May 15;281(2):240-55 |
1 | J:246732 Saller MM, Huettl RE, Hanuschick P, Amend AL, Alberton P, Aszodi A, Huber AB, The role of Sema3-Npn-1 signaling during diaphragm innervation and muscle development. J Cell Sci. 2016 Sep 01;129(17):3295-308 |
1 | J:45303 Tole S, Christian C, Grove EA, Early specification and autonomous development of cortical fields in the mouse hippocampus. Development. 1997 Dec;124(24):4959-70 |
1* | J:64588 Toresson H, Potter SS, Campbell K, Genetic control of dorsal-ventral identity in the telencephalon: opposing roles for pax6 and gsh2. Development. 2000 Oct;127(20):4361-71 |
Pou3f2 POU domain, class 3, transcription factor 2 (Synonyms: 9430075J19Rik, A230098E07Rik, Brn-2, Brn2, Otf7) | |
Results | Reference |
1 | J:113118 Miyagi S, Nishimoto M, Saito T, Ninomiya M, Sawamoto K, Okano H, Muramatsu M, Oguro H, Iwama A, Okuda A, The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon. J Biol Chem. 2006 May 12;281(19):13374-81 |
1 | J:331478 Monko T, Rebertus J, Stolley J, Salton SR, Nakagawa Y, Thalamocortical axons regulate neurogenesis and laminar fates in the early sensory cortex. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2201355119 |
1* | J:231073 Oishi K, Aramaki M, Nakajima K, Mutually repressive interaction between Brn1/2 and Rorb contributes to the establishment of neocortical layer 2/3 and layer 4. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3371-6 |
1* | J:98542 Rowan S, Cepko CL, A POU factor binding site upstream of the Chx10 homeobox gene is required for Chx10 expression in subsets of retinal progenitor cells and bipolar cells. Dev Biol. 2005 May 15;281(2):240-55 |
1* | J:210661 Seto Y, Ishiwata S, Hoshino M, Characterization of Olig2 expression during cerebellar development. Gene Expr Patterns. 2014 May;15(1):1-7 |
1 | J:157301 Siegenthaler JA, Ashique AM, Zarbalis K, Patterson KP, Hecht JH, Kane MA, Folias AE, Choe Y, May SR, Kume T, Napoli JL, Peterson AS, Pleasure SJ, Retinoic acid from the meninges regulates cortical neuron generation. Cell. 2009 Oct 30;139(3):597-609 |
1 | J:152951 Sillitoe RV, Gopal N, Joyner AL, Embryonic origins of ZebrinII parasagittal stripes and establishment of topographic Purkinje cell projections. Neuroscience. 2009 Sep 1;162(3):574-88 |
1 | J:298594 Stepien BK, Naumann R, Holtz A, Helppi J, Huttner WB, Vaid S, Lengthening Neurogenic Period during Neocortical Development Causes a Hallmark of Neocortex Expansion. Curr Biol. 2020 Nov 2;30(21):4227-4237.e5 |
1 | J:77999 Sugitani Y, Nakai S, Minowa O, Nishi M, Jishage K, Kawano H, Mori K, Ogawa M, Noda T, Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. Genes Dev. 2002 Jul 15;16(14):1760-5 |
1 | J:188109 Tan SL, Nishi M, Ohtsuka T, Matsui T, Takemoto K, Kamio-Miura A, Aburatani H, Shinkai Y, Kageyama R, Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development. Development. 2012 Oct;139(20):3806-16 |
1 | J:278287 Tang T, Zhang Y, Wang Y, Cai Z, Lu Z, Li L, Huang R, Hagelkruys A, Matthias P, Zhang H, Seiser C, Xie Y, HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development. Neuron. 2019 Mar 20;101(6):1117-1133.e5 |
1 | J:235720 Wang PS, Chou FS, Ramachandran S, Xia S, Chen HY, Guo F, Suraneni P, Maher BJ, Li R, Crucial roles of the Arp2/3 complex during mammalian corticogenesis. Development. 2016 Aug 1;143(15):2741-52 |
1 | J:177905 Yamasaki T, Kawasaki H, Arakawa S, Shimizu K, Shimizu S, Reiner O, Okano H, Nishina S, Azuma N, Penninger JM, Katada T, Nishina H, Stress-Activated Protein Kinase MKK7 Regulates Axon Elongation in the Developing Cerebral Cortex. J Neurosci. 2011 Nov 16;31(46):16872-16883 |
1 | J:328995 Zhang SF, Dai SK, Du HZ, Wang H, Li XG, Tang Y, Liu CM, The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis. Stem Cell Reports. 2022 Sep 13;17(9):2064-2080 |
Pou3f3 POU domain, class 3, transcription factor 3 (Synonyms: Brn-1, Brn1, HST011, Otf8, urehr2) | |
Results | Reference |
1 | J:228026 Capecchi MR, Pozner A, ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination. Nat Commun. 2015;6:8763 |
1 | J:99355 Depaepe V, Suarez-Gonzalez N, Dufour A, Passante L, Gorski JA, Jones KR, Ledent C, Vanderhaeghen P, Ephrin signalling controls brain size by regulating apoptosis of neural progenitors. Nature. 2005 Jun 30;435(7046):1244-50 |
1 | J:144651 Farkas LM, Haffner C, Giger T, Khaitovich P, Nowick K, Birchmeier C, Paabo S, Huttner WB, Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex. Neuron. 2008 Oct 9;60(1):40-55 |
1 | J:269420 Franz H, Villarreal A, Heidrich S, Videm P, Kilpert F, Mestres I, Calegari F, Backofen R, Manke T, Vogel T, DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex. Nucleic Acids Res. 2019 Jan 10;47(1):168-183 |
1 | J:96824 Friedrich RP, Schlierf B, Tamm ER, Bosl MR, Wegner M, The class III POU domain protein Brn-1 can fully replace the related Oct-6 during schwann cell development and myelination. Mol Cell Biol. 2005 Mar;25(5):1821-9 |
1 | J:101055 Kuo G, Arnaud L, Kronstad-O'Brien P, Cooper JA, Absence of Fyn and Src causes a reeler-like phenotype. J Neurosci. 2005 Sep 14;25(37):8578-86 |
1 | J:113118 Miyagi S, Nishimoto M, Saito T, Ninomiya M, Sawamoto K, Okano H, Muramatsu M, Oguro H, Iwama A, Okuda A, The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon. J Biol Chem. 2006 May 12;281(19):13374-81 |
1 | J:250180 Nakagawa N, Yagi H, Kato K, Takematsu H, Oka S, Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy. Sci Rep. 2015 Jun 10;5:11163 |
1 | J:309384 Neirijnck Y, Reginensi A, Renkema KY, Massa F, Kozlov VM, Dhib H, Bongers EMHF, Feitz WF, van Eerde AM, Lefebvre V, Knoers NVAM, Tabatabaei M, Schulz H, McNeill H, Schaefer F, Wegner M, Sock E, Schedl A, Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT). Kidney Int. 2018 May;93(5):1142-1153 |
1 | J:240398 Ogino H, Hisanaga A, Kohno T, Kondo Y, Okumura K, Kamei T, Sato T, Asahara H, Tsuiji H, Fukata M, Hattori M, Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin. J Neurosci. 2017 Mar 22;37(12):3181-3191 |
1* | J:292351 Rodrigues DC, Harvey EM, Suraj R, Erickson SL, Mohammad L, Ren M, Liu H, He G, Kaplan DR, Ellis J, Yang G, Methylglyoxal couples metabolic and translational control of Notch signalling in mammalian neural stem cells. Nat Commun. 2020 Apr 24;11(1):2018 |
1 | J:77999 Sugitani Y, Nakai S, Minowa O, Nishi M, Jishage K, Kawano H, Mori K, Ogawa M, Noda T, Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. Genes Dev. 2002 Jul 15;16(14):1760-5 |
1 | J:170348 Westerlund N, Zdrojewska J, Padzik A, Komulainen E, Bjorkblom B, Rannikko E, Tararuk T, Garcia-Frigola C, Sandholm J, Nguyen L, Kallunki T, Courtney MJ, Coffey ET, Phosphorylation of SCG10/stathmin-2 determines multipolar stage exit and neuronal migration rate. Nat Neurosci. 2011 Mar;14(3):305-13 |
1 | J:147307 Yokota Y, Kim WY, Chen Y, Wang X, Stanco A, Komuro Y, Snider W, Anton ES, The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex. Neuron. 2009 Jan 15;61(1):42-56 |
1 | J:225537 Zhang J, Taylor RJ, La Torre A, Wilken MS, Cox KE, Reh TA, Vetter ML, Ezh2 maintains retinal progenitor proliferation, transcriptional integrity, and the timing of late differentiation. Dev Biol. 2015 Jul 15;403(2):128-38 |
Pou3f4 POU domain, class 3, transcription factor 4 (Synonyms: Brn4, BRN-4, Otf9) | |
Results | Reference |
1 | J:179898 Coate TM, Raft S, Zhao X, Ryan AK, Crenshaw EB 3rd, Kelley MW, Otic Mesenchyme Cells Regulate Spiral Ganglion Axon Fasciculation through a Pou3f4/EphA4 Signaling Pathway. Neuron. 2012 Jan 12;73(1):49-63 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:176201 Kordowich S, Collombat P, Mansouri A, Serup P, Arx and Nkx2.2 compound deficiency redirects pancreatic alpha- and beta-cell differentiation to a somatostatin/ghrelin co-expressing cell lineage. BMC Dev Biol. 2011;11:52 |
1* | J:59387 Phippard D, Boyd Y, Reed V, Fisher G, Masson WK, Evans EP, Saunders JC, Crenshaw EB 3rd, The sex-linked fidget mutation abolishes Brn4/Pou3f4 gene expression in the embryonic inner ear. Hum Mol Genet. 2000 Jan 1;9(1):79-85 |
1* | J:226319 Phippard D, Heydemann A, Lechner M, Lu L, Lee D, Kyin T, Crenshaw EB 3rd, Changes in the subcellular localization of the Brn4 gene product precede mesenchymal remodeling of the otic capsule. Hear Res. 1998 Jun;120(1-2):77-85 |
1 | J:223566 Raft S, Coate TM, Kelley MW, Crenshaw EB 3rd, Wu DK, Pou3f4-mediated regulation of ephrin-b2 controls temporal bone development in the mouse. PLoS One. 2014;9(10):e109043 |
1 | J:77999 Sugitani Y, Nakai S, Minowa O, Nishi M, Jishage K, Kawano H, Mori K, Ogawa M, Noda T, Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. Genes Dev. 2002 Jul 15;16(14):1760-5 |
Pou4f1 POU domain, class 4, transcription factor 1 (Synonyms: Brn-3, Brn3, Brn-3.0, Brn3a, E130119J07Rik) | |
Results | Reference |
1 | J:273194 Anderson SR, Zhang J, Steele MR, Romero CO, Kautzman AG, Schafer DP, Vetter ML, Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia. J Neurosci. 2019 Mar 13;39(11):2025-2040 |
1 | J:287985 Bosze B, Moon MS, Kageyama R, Brown NL, Simultaneous Requirements for Hes1 in Retinal Neurogenesis and Optic Cup-Stalk Boundary Maintenance. J Neurosci. 2020 Feb 12;40(7):1501-1513 |
1 | J:304642 Dupacova N, Antosova B, Paces J, Kozmik Z, Meis homeobox genes control progenitor competence in the retina. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2013136118 |
1 | J:160656 Eng SR, Dykes IM, Lanier J, Fedtsova N, Turner EE, POU-domain factor Brn3a regulates both distinct and common programs of gene expression in the spinal and trigeminal sensory ganglia. Neural Dev. 2007;2:3 |
1 | J:139182 Farooqui-Kabir SR, Diss JK, Henderson D, Marber MS, Latchman DS, Budhram-Mahadeo V, Heads RJ, Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression. Cell Stress Chaperones. 2008 Sep;13(3):297-312 |
1* | J:135584 Fedtsova N, Quina LA, Wang S, Turner EE, Regulation of the development of tectal neurons and their projections by transcription factors Brn3a and Pax7. Dev Biol. 2008 Apr 1;316(1):6-20 |
1* | J:350259 Fernandez-Nogales M, Lopez-Cascales MT, Murcia-Belmonte V, Escalante A, Fernandez-Albert J, Munoz-Viana R, Barco A, Herrera E, Multiomic Analysis of Neurons with Divergent Projection Patterns Identifies Novel Regulators of Axon Pathfinding. Adv Sci (Weinh). 2022 Oct;9(29):e2200615 |
1 | J:266784 Gay MH, Valenta T, Herr P, Paratore-Hari L, Basler K, Sommer L, Distinct adhesion-independent functions of beta-catenin control stage-specific sensory neurogenesis and proliferation. BMC Biol. 2015 Apr 11;13:24 |
1 | J:34809 Gerrero MR, McEvilly RJ, Turner E, Lin CR, O'Connell S, Jenne KJ, Hobbs MV, Rosenfeld MG, Brn-3.0: a POU-domain protein expressed in the sensory, immune, and endocrine systems that functions on elements distinct from known octamer motifs. Proc Natl Acad Sci U S A. 1993 Nov 15;90(22):10841-5 |
1 | J:254641 Groman-Lupa S, Adewumi J, Park KU, Brzezinski Iv JA, The Transcription Factor Prdm16 Marks a Single Retinal Ganglion Cell Subtype in the Mouse Retina. Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5421-5433 |
1 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1 | J:70744 Huang EJ, Liu W, Fritzsch B, Bianchi LM, Reichardt LF, Xiang M, Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons. Development. 2001 Jul;128(13):2421-32 |
1 | J:279675 Jones I, Hagglund AC, Carlsson L, Reduced mTORC1-signalling in retinal progenitor cells leads to visual pathway dysfunction. Biol Open. 2019 Aug 1;8(8):bio044370 |
1 | J:169455 Kim D, Ackerman SL, The UNC5C netrin receptor regulates dorsal guidance of mouse hindbrain axons. J Neurosci. 2011 Feb 9;31(6):2167-79 |
1* | J:107595 Landsberg RL, Awatramani RB, Hunter NL, Farago AF, DiPietrantonio HJ, Rodriguez CI, Dymecki SM, Hindbrain rhombic lip is comprised of discrete progenitor cell populations allocated by Pax6. Neuron. 2005 Dec 22;48(6):933-47 |
1 | J:254469 Li J, Wang S, Anderson C, Zhao F, Qin Y, Wu D, Wu X, Liu J, He X, Zhao J, Zhang J, Requirement of Smad4 from Ocular Surface Ectoderm for Retinal Development. PLoS One. 2016;11(8):e0159639 |
1 | J:316103 Li X, Gaillard F, Monckton EA, Glubrecht DD, Persad AR, Moser M, Sauve Y, Godbout R, Loss of AP-2delta reduces retinal ganglion cell numbers and axonal projections to the superior colliculus. Mol Brain. 2016 Jun 4;9(1):62 |
1 | J:143462 Liu Z, Li H, Hu X, Yu L, Liu H, Han R, Colella R, Mower GD, Chen Y, Qiu M, Control of precerebellar neuron development by Olig3 bHLH transcription factor. J Neurosci. 2008 Oct 1;28(40):10124-33 |
1 | J:137605 Manuel M, Pratt T, Liu M, Jeffery G, Price DJ, Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance. BMC Dev Biol. 2008;8:59 |
1 | J:214082 Maurer KA, Riesenberg AN, Brown NL, Notch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina. Development. 2014 Aug;141(16):3243-54 |
1 | J:37118 McEvilly RJ, Erkman L, Luo L, Sawchenko PE, Ryan AF, Rosenfeld MG, Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature. 1996 Dec 12;384(6609):574-7 |
1* | J:278827 Murcia-Belmonte V, Coca Y, Vegar C, Negueruela S, de Juan Romero C, Valino AJ, Sala S, DaSilva R, Kania A, Borrell V, Martinez LM, Erskine L, Herrera E, A Retino-retinal Projection Guided by Unc5c Emerged in Species with Retinal Waves. Curr Biol. 2019 Apr 1;29(7):1149-1160.e4 |
1 | J:340810 Nishida K, Matsumura S, Uchida H, Abe M, Sakimura K, Badea TC, Kobayashi T, Brn3a controls the soma localization and axonal extension patterns of developing spinal dorsal horn neurons. PLoS One. 2023;18(9):e0285295 |
1 | J:328038 Niu F, Che P, Yang Z, Zhang J, Yang L, Zhuang M, Ou X, Ji SJ, m(6)A regulation of cortical and retinal neurogenesis is mediated by the redundant m(6)A readers YTHDFs. iScience. 2022 Sep 16;25(9):104908 |
1 | J:335863 Oda M, Yamamoto H, Matsumoto H, Ishizaki Y, Shibasaki K, TRPC5 regulates axonal outgrowth in developing retinal ganglion cells. Lab Invest. 2020 Feb;100(2):297-310 |
1 | J:181398 Ogata-Iwao M, Inatani M, Iwao K, Takihara Y, Nakaishi-Fukuchi Y, Irie F, Sato S, Furukawa T, Yamaguchi Y, Tanihara H, Heparan sulfate regulates intraretinal axon pathfinding by retinal ganglion cells. Invest Ophthalmol Vis Sci. 2011 Aug;52(9):6671-9 |
1 | J:206963 Orieux G, Picault L, Slembrouck A, Roger JE, Guillonneau X, Sahel JA, Saule S, McPherson JP, Goureau O, Involvement of Bcl-2-associated transcription factor 1 in the differentiation of early-born retinal cells. J Neurosci. 2014 Jan 22;34(4):1530-41 |
2 | J:123264 Quina LA, Pak W, Lanier J, Banwait P, Gratwick K, Liu Y, Velasquez T, O'Leary DD, Goulding M, Turner EE, Brn3a-expressing retinal ganglion cells project specifically to thalamocortical and collicular visual pathways. J Neurosci. 2005 Dec 14;25(50):11595-604 |
3 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1 | J:160556 Schoenmann Z, Assa-Kunik E, Tiomny S, Minis A, Haklai-Topper L, Arama E, Yaron A, Axonal degeneration is regulated by the apoptotic machinery or a NAD+-sensitive pathway in insects and mammals. J Neurosci. 2010 May 5;30(18):6375-86 |
1 | J:277160 Sherrill HE, Jean P, Driver EC, Sanders TR, Fitzgerald TS, Moser T, Kelley MW, Pou4f1 Defines a Subgroup of Type I Spiral Ganglion Neurons and Is Necessary for Normal Inner Hair Cell Presynaptic Ca(2+) Signaling. J Neurosci. 2019 Jul 3;39(27):5284-5298 |
1 | J:166950 Shi M, Zheng MH, Liu ZR, Hu ZL, Huang Y, Chen JY, Zhao G, Han H, Ding YQ, DCC is specifically required for the survival of retinal ganglion and displaced amacrine cells in the developing mouse retina. Dev Biol. 2010 Dec 1;348(1):87-96 |
1 | J:154456 Thompson H, Andrews W, Parnavelas JG, Erskine L, Robo2 is required for Slit-mediated intraretinal axon guidance. Dev Biol. 2009 Nov 15;335(2):418-26 |
1* | J:41168 Turner EE, Jenne KJ, Rosenfeld MG, Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid. Neuron. 1994 Jan;12(1):205-18 |
1 | J:167837 Waite MR, Skidmore JM, Billi AC, Martin JF, Martin DM, GABAergic and glutamatergic identities of developing midbrain Pitx2 neurons. Dev Dyn. 2011 Feb;240(2):333-46 |
1 | J:73779 Wang SW, Mu X, Bowers WJ, Kim DS, Plas DJ, Crair MC, Federoff HJ, Gan L, Klein WH, Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth. Development. 2002 Jan;129(2):467-77 |
1* | J:107704 Xiang M, Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors. Dev Biol. 1998 May 15;197(2):155-69 |
1* | J:160668 Yang H, Gan J, Xie X, Deng M, Feng L, Chen X, Gao Z, Gan L, Gfi1-Cre knock-in mouse line: A tool for inner ear hair cell-specific gene deletion. Genesis. 2010 Apr 13;48(6):400-406 |
1* | J:236376 Zheng D, Yang X, Sheng D, Yu D, Liang G, Guo L, Xu M, Hu X, He D, Yang Y, Wang Y, Pou4f2-GFP knock-in mouse line: A model for studying retinal ganglion cell development. Genesis. 2016 Oct;54(10):534-541 |
1 | J:309104 Zheng MH, Shi M, Pei Z, Gao F, Han H, Ding YQ, The transcription factor RBP-J is essential for retinal cell differentiation and lamination. Mol Brain. 2009 Dec 18;2:38 |
Pou4f2 POU domain, class 4, transcription factor 2 (Synonyms: Brn-3.2, Brn-3b, Brn3b, mBrn3-3R, Pou4f-rs1) | |
Results | Reference |
1 | J:146558 Cho JH, Mu X, Wang SW, Klein WH, Retinal ganglion cell death and optic nerve degeneration by genetic ablation in adult mice. Exp Eye Res. 2009 Mar;88(3):542-52 |
2 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1 | J:95327 de Melo J, Du G, Fonseca M, Gillespie LA, Turk WJ, Rubenstein JL, Eisenstat DD, Dlx1 and Dlx2 function is necessary for terminal differentiation and survival of late-born retinal ganglion cells in the developing mouse retina. Development. 2005 Jan;132(2):311-22 |
1 | J:172162 de Melo J, Zhou QP, Zhang Q, Zhang S, Fonseca M, Wigle JT, Eisenstat DD, Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development. Nucleic Acids Res. 2008 Feb;36(3):872-84 |
1 | J:147448 Ding Q, Chen H, Xie X, Libby RT, Tian N, Gan L, BARHL2 differentially regulates the development of retinal amacrine and ganglion neurons. J Neurosci. 2009 Apr 1;29(13):3992-4003 |
1 | J:139182 Farooqui-Kabir SR, Diss JK, Henderson D, Marber MS, Latchman DS, Budhram-Mahadeo V, Heads RJ, Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression. Cell Stress Chaperones. 2008 Sep;13(3):297-312 |
1* | J:339296 Fries M, Brown TW, Jolicoeur C, Boulan B, Boudreau-Pinsonneault C, Javed A, Abram P, Cayouette M, Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections. Cell Rep. 2023 Aug 16;42(8):112985 |
1 | J:32903 Gan L, Xiang M, Zhou L, Wagner DS, Klein WH, Nathans J, POU domain factor Brn-3b is required for the development of a large set of retinal ganglion cells. Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):3920-5 |
1 | J:249145 Goetz JJ, Laboissonniere LA, Wester AK, Lynch MR, Trimarchi JM, Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression. PLoS One. 2016;11(3):e0150878 |
1 | J:237540 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R, The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development. 2016 Nov 15;143(22):4182-4192 |
1 | J:94392 Herrera E, Marcus R, Li S, Williams SE, Erskine L, Lai E, Mason C, Foxd1 is required for proper formation of the optic chiasm. Development. 2004 Nov;131(22):5727-39 |
1 | J:70744 Huang EJ, Liu W, Fritzsch B, Bianchi LM, Reichardt LF, Xiang M, Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons. Development. 2001 Jul;128(13):2421-32 |
1 | J:199663 Jiang Y, Ding Q, Xie X, Libby RT, Lefebvre V, Gan L, Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells. J Biol Chem. 2013 Jun 21;288(25):18429-38 |
1 | J:164295 Jin K, Jiang H, Mo Z, Xiang M, Early B-cell factors are required for specifying multiple retinal cell types and subtypes from postmitotic precursors. J Neurosci. 2010 Sep 8;30(36):11902-16 |
1 | J:267504 Kiyama T, Chen CK, Wang SW, Pan P, Ju Z, Wang J, Takada S, Klein WH, Mao CA, Essential roles of mitochondrial biogenesis regulator Nrf1 in retinal development and homeostasis. Mol Neurodegener. 2018 Oct 17;13(1):56 |
1 | J:130570 Mao CA, Kiyama T, Pan P, Furuta Y, Hadjantonakis AK, Klein WH, Eomesodermin, a target gene of Pou4f2, is required for retinal ganglion cell and optic nerve development in the mouse. Development. 2008 Jan;135(2):271-80 |
1 | J:293331 Martinez-Chavez E, Scheerer C, Wizenmann A, Blaess S, The zinc-finger transcription factor GLI3 is a regulator of precerebellar neuronal migration. Development. 2018 Dec 17;145(24):dev166033 |
2 | J:261834 Maskell LJ, Qamar K, Babakr AA, Hawkins TA, Heads RJ, Budhram-Mahadeo VS, Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart. Cell Death Dis. 2017 Jun 8;8(6):e2861 |
1 | J:37118 McEvilly RJ, Erkman L, Luo L, Sawchenko PE, Ryan AF, Rosenfeld MG, Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature. 1996 Dec 12;384(6609):574-7 |
1 | J:235721 Menuchin-Lasowski Y, Oren-Giladi P, Xie Q, Ezra-Elia R, Ofri R, Peled-Hajaj S, Farhy C, Higashi Y, Van de Putte T, Kondoh H, Huylebroeck D, Cvekl A, Ashery-Padan R, Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals. Development. 2016 Aug 1;143(15):2829-41 |
2 | J:133489 Qiu F, Jiang H, Xiang M, A comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursors. J Neurosci. 2008 Mar 26;28(13):3392-403 |
1* | J:232723 Qu C, Bian D, Li X, Xiao J, Wu C, Li Y, Jiang T, Zhou X, Qu J, Chen JG, Transient Expression of Fez Family Zinc Finger 2 Protein Regulates the Brn3b Gene in Developing Retinal Ganglion Cells. J Biol Chem. 2016 Apr 1;291(14):7661-8 |
1 | J:123264 Quina LA, Pak W, Lanier J, Banwait P, Gratwick K, Liu Y, Velasquez T, O'Leary DD, Goulding M, Turner EE, Brn3a-expressing retinal ganglion cells project specifically to thalamocortical and collicular visual pathways. J Neurosci. 2005 Dec 14;25(50):11595-604 |
1 | J:158918 Renier N, Schonewille M, Giraudet F, Badura A, Tessier-Lavigne M, Avan P, De Zeeuw CI, Chedotal A, Genetic dissection of the function of hindbrain axonal commissures. PLoS Biol. 2010;8(3):e1000325 |
1 | J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77 |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
1* | J:41168 Turner EE, Jenne KJ, Rosenfeld MG, Brn-3.2: a Brn-3-related transcription factor with distinctive central nervous system expression and regulation by retinoic acid. Neuron. 1994 Jan;12(1):205-18 |
1 | J:73779 Wang SW, Mu X, Bowers WJ, Kim DS, Plas DJ, Crair MC, Federoff HJ, Gan L, Klein WH, Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth. Development. 2002 Jan;129(2):467-77 |
1* | J:107704 Xiang M, Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors. Dev Biol. 1998 May 15;197(2):155-69 |
1* | J:160668 Yang H, Gan J, Xie X, Deng M, Feng L, Chen X, Gao Z, Gan L, Gfi1-Cre knock-in mouse line: A tool for inner ear hair cell-specific gene deletion. Genesis. 2010 Apr 13;48(6):400-406 |
1 | J:225537 Zhang J, Taylor RJ, La Torre A, Wilken MS, Cox KE, Reh TA, Vetter ML, Ezh2 maintains retinal progenitor proliferation, transcriptional integrity, and the timing of late differentiation. Dev Biol. 2015 Jul 15;403(2):128-38 |
1 | J:241572 Zhang Q, Zagozewski J, Cheng S, Dixit R, Zhang S, de Melo J, Mu X, Klein WH, Brown NL, Wigle JT, Schuurmans C, Eisenstat DD, Regulation of Brn3b by DLX1 and DLX2 is required for retinal ganglion cell differentiation in the vertebrate retina. Development. 2017 May 01;144(9):1698-1711 |
1* | J:236376 Zheng D, Yang X, Sheng D, Yu D, Liang G, Guo L, Xu M, Hu X, He D, Yang Y, Wang Y, Pou4f2-GFP knock-in mouse line: A model for studying retinal ganglion cell development. Genesis. 2016 Oct;54(10):534-541 |
1 | J:217063 Zou M, Luo H, Xiang M, Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord. Dev Dyn. 2015 Jan;244(1):86-97 |
Pou4f3 POU domain, class 4, transcription factor 3 (Synonyms: Brn-3.1, Brn3.1, Brn3c) | |
Results | Reference |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
1 | J:98458 Kiernan AE, Pelling AL, Leung KK, Tang AS, Bell DM, Tease C, Lovell-Badge R, Steel KP, Cheah KS, Sox2 is required for sensory organ development in the mammalian inner ear. Nature. 2005 Apr 21;434(7036):1031-5 |
1 | J:316103 Li X, Gaillard F, Monckton EA, Glubrecht DD, Persad AR, Moser M, Sauve Y, Godbout R, Loss of AP-2delta reduces retinal ganglion cell numbers and axonal projections to the superior colliculus. Mol Brain. 2016 Jun 4;9(1):62 |
1 | J:37118 McEvilly RJ, Erkman L, Luo L, Sawchenko PE, Ryan AF, Rosenfeld MG, Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons. Nature. 1996 Dec 12;384(6609):574-7 |
1 | J:335097 Qin T, Ho CC, Wang B, Hui CC, Sham MH, Sufu- and Spop-mediated regulation of Gli2 is essential for the control of mammalian cochlear hair cell differentiation. Proc Natl Acad Sci U S A. 2022 Oct 25;119(43):e2206571119 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1* | J:268084 Saha A, Tiwari S, Dharmarajan S, Otteson DC, Belecky-Adams TL, Class I histone deacetylases in retinal progenitors and differentiating ganglion cells. Gene Expr Patterns. 2018 Dec;30:37-48 |
1 | J:73779 Wang SW, Mu X, Bowers WJ, Kim DS, Plas DJ, Crair MC, Federoff HJ, Gan L, Klein WH, Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth. Development. 2002 Jan;129(2):467-77 |
1* | J:107704 Xiang M, Requirement for Brn-3b in early differentiation of postmitotic retinal ganglion cell precursors. Dev Biol. 1998 May 15;197(2):155-69 |
Pou5f1 POU domain, class 5, transcription factor 1 (Synonyms: Oct-3, Oct-3/4, Oct3/4, Oct-4, Oct4, Otf-3, Otf3, Otf3g, Otf3-rs7, Otf-4, Otf4) | |
Results | Reference |
2* | J:186276 Celebi C, van Montfoort A, Skory V, Kieffer E, Kuntz S, Mark M, Viville S, Tex 19 Paralogs Exhibit a Gonad and Placenta-Specific Expression in the Mouse. J Reprod Dev. 2012 Jul 3;58(3):360-5 |
1 | J:316527 Chen HH, Welling M, Bloch DB, Munoz J, Mientjes E, Chen X, Tramp C, Wu J, Yabuuchi A, Chou YF, Buecker C, Krainer A, Willemsen R, Heck AJ, Geijsen N, DAZL limits pluripotency, differentiation, and apoptosis in developing primordial germ cells. Stem Cell Reports. 2014 Nov 11;3(5):892-904 |
1 | J:167041 Cook MS, Munger SC, Nadeau JH, Capel B, Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background. Development. 2011 Jan;138(1):23-32 |
1* | J:143899 Dettman EJ, Justice MJ, The zinc finger SET domain gene Prdm14 is overexpressed in lymphoblastic lymphomas with retroviral insertions at Evi32. PLoS One. 2008;3(11):e3823 |
1 | J:250152 Hu X, Tang Z, Li Y, Liu W, Zhang S, Wang B, Tian Y, Zhao Y, Ran H, Liu W, Feng GS, Shuai J, Wang H, Lu Z, Deletion of the tyrosine phosphatase Shp2 in Sertoli cells causes infertility in mice. Sci Rep. 2015 Aug 12;5:12982 |
1 | J:252799 Itou D, Shiromoto Y, Yukiho SY, Ishii C, Nishimura T, Ogonuki N, Ogura A, Hasuwa H, Fujihara Y, Kuramochi-Miyagawa S, Nakano T, Induction of DNA methylation by artificial piRNA production in male germ cells. Curr Biol. 2015 Mar 30;25(7):901-6 |
1* | J:133713 Kuntz S, Kieffer E, Bianchetti L, Lamoureux N, Fuhrmann G, Viville S, Tex19, a mammalian-specific protein with a restricted expression in pluripotent stem cells and germ line. Stem Cells. 2008 Mar;26(3):734-44 |
1* | J:170274 Li L, Kwon HJ, Harada H, Ohshima H, Cho SW, Jung HS, Expression patterns of ABCG2, Bmi-1, Oct-3/4, and Yap in the developing mouse incisor. Gene Expr Patterns. 2011 Mar-Apr;11(3-4):163-70 |
1* | J:86170 Menke DB, Koubova J, Page DC, Sexual differentiation of germ cells in XX mouse gonads occurs in an anterior-to-posterior wave. Dev Biol. 2003 Oct 15;262(2):303-12 |
1 | J:158526 Naillat F, Prunskaite-Hyyrylainen R, Pietila I, Sormunen R, Jokela T, Shan J, Vainio SJ, Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development. Hum Mol Genet. 2010 Apr 15;19(8):1539-50 |
1* | J:193587 Nakagawa E, Zhang L, Kim EJ, Shin JO, Cho SW, Ohshima H, Jung HS, The novel function of Oct3/4 in mouse tooth development. Histochem Cell Biol. 2012 Mar;137(3):367-76 |
1 | J:296955 Niu W, Spradling AC, Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20015-20026 |
1 | J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34 |
1* | J:46643 Pesce M, Wang X, Wolgemuth DJ, Scholer H, Differential expression of the Oct-4 transcription factor during mouse germ cell differentiation. Mech Dev. 1998 Feb;71(1-2):89-98 |
1 | J:197599 Pitetti JL, Calvel P, Romero Y, Conne B, Truong V, Papaioannou MD, Schaad O, Docquier M, Herrera PL, Wilhelm D, Nef S, Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice. PLoS Genet. 2013;9(1):e1003160 |
2* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1* | J:249296 Spiller CM, Wilhelm D, Koopman P, Retinoblastoma 1 protein modulates XY germ cell entry into G1/G0 arrest during fetal development in mice. Biol Reprod. 2010 Feb;82(2):433-43 |
1 | J:362758 Zhang L, Li Y, Hu Y, Chen M, Cen C, Chen M, Lin L, Zhou J, Wang M, Cui X, Tang F, Gao F, Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression. FASEB J. 2022 Feb;36(2):e22131 |
Pou6f2 POU domain, class 6, transcription factor 2 (Synonyms: D130006K24Rik, RPF-1) | |
Results | Reference |
2 | J:117767 Di Renzo F, Doneda L, Menegola E, Sardella M, De Vecchi G, Collini P, Spreafico F, Fossati-Bellani F, Giavini E, Radice P, Perotti D, The murine Pou6f2 gene is temporally and spatially regulated during kidney embryogenesis and its human homolog is overexpressed in a subset of Wilms tumors. J Pediatr Hematol Oncol. 2006 Dec;28(12):791-7 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
Ppara peroxisome proliferator activated receptor alpha (Synonyms: 4933429D07Rik, Nr1c1, Ppar, PPAR-alpha, PPARalpha) | |
Results | Reference |
1 | J:2943 Beck F, Plummer S, Senior PV, Byrne S, Green S, Brammar WJ, The ontogeny of peroxisome-proliferator-activated receptor gene expression in the mouse and rat. Proc R Soc Lond B Biol Sci. 1992 Feb 22;247(1319):83-7 |
1 | J:324530 Fonseca TL, Russo SC, Luongo C, Salvatore D, Bianco AC, Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 May 1;163(5) |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
1* | J:189008 Jia Y, Viswakarma N, Crawford SE, Sarkar J, Sambasiva Rao M, Karpus WJ, Kanwar YS, Zhu YJ, Reddy JK, Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. Mech Dev. 2012 Sep;129(9-12):193-207 |
1* | J:19422 Kliewer SA, Forman BM, Blumberg B, Ong ES, Borgmeyer U, Mangelsdorf DJ, Umesono K, Evans RM, Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7355-9 |
1* | J:65091 Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP, Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest. 2000 Oct;106(7):847-56 |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
2 | J:71272 Michalik L, Desvergne B, Tan NS, Basu-Modak S, Escher P, Rieusset J, Peters JM, Kaya G, Gonzalez FJ, Zakany J, Metzger D, Chambon P, Duboule D, Wahli W, Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice. J Cell Biol. 2001 Aug 20;154(4):799-814 |
1* | J:40975 Sack MN, Disch DL, Rockman HA, Kelly DP, A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6438-43 |
1 | J:313946 Wada Y, Maekawa M, Ohnishi T, Balan S, Matsuoka S, Iwamoto K, Iwayama Y, Ohba H, Watanabe A, Hisano Y, Nozaki Y, Toyota T, Shimogori T, Itokawa M, Kobayashi T, Yoshikawa T, Peroxisome proliferator-activated receptor alpha as a novel therapeutic target for schizophrenia. EBioMedicine. 2020 Dec;62:103130 |
Ppard peroxisome proliferator activator receptor delta (Synonyms: Nr1c2, NUC1, Peroxisome proliferator-activated receptor beta, Pparb, Pparb/d, PPAR-delta, PPARdelta/beta) | |
Results | Reference |
2 | J:96826 Di-Poi N, Ng CY, Tan NS, Yang Z, Hemmings BA, Desvergne B, Michalik L, Wahli W, Epithelium-mesenchyme interactions control the activity of peroxisome proliferator-activated receptor beta/delta during hair follicle development. Mol Cell Biol. 2005 Mar;25(5):1696-712 |
1* | J:258542 Hupe M, Li MX, Kneitz S, Davydova D, Yokota C, Kele-Olovsson J, Hot B, Stenman JM, Gessler M, Gene expression profiles of brain endothelial cells during embryonic development at bulk and single-cell levels. Sci Signal. 2017 Jul 11;10(487) |
1* | J:189008 Jia Y, Viswakarma N, Crawford SE, Sarkar J, Sambasiva Rao M, Karpus WJ, Kanwar YS, Zhu YJ, Reddy JK, Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. Mech Dev. 2012 Sep;129(9-12):193-207 |
1* | J:19422 Kliewer SA, Forman BM, Blumberg B, Ong ES, Borgmeyer U, Mangelsdorf DJ, Umesono K, Evans RM, Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7355-9 |
2 | J:71272 Michalik L, Desvergne B, Tan NS, Basu-Modak S, Escher P, Rieusset J, Peters JM, Kaya G, Gonzalez FJ, Zakany J, Metzger D, Chambon P, Duboule D, Wahli W, Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice. J Cell Biol. 2001 Aug 20;154(4):799-814 |
1 | J:107381 Nadra K, Anghel SI, Joye E, Tan NS, Basu-Modak S, Trono D, Wahli W, Desvergne B, Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta. Mol Cell Biol. 2006 Apr;26(8):3266-81 |
1 | J:316584 Outhwaite JE, Natale BV, Natale DR, Simmons DG, Expression of aldehyde dehydrogenase family 1, member A3 in glycogen trophoblast cells of the murine placenta. Placenta. 2015 Mar;36(3):304-11 |
Pparg peroxisome proliferator activated receptor gamma (Synonyms: Nr1c3, PPAR-gamma, PPARgamma, Ppar-gamma2, PPARgamma2) | |
Results | Reference |
1 | J:239948 Al Alam D, El Agha E, Sakurai R, Kheirollahi V, Moiseenko A, Danopoulos S, Shrestha A, Schmoldt C, Quantius J, Herold S, Chao CM, Tiozzo C, De Langhe S, Plikus MV, Thornton M, Grubbs B, Minoo P, Rehan VK, Bellusci S, Evidence for the involvement of fibroblast growth factor 10 in lipofibroblast formation during embryonic lung development. Development. 2015 Dec 01;142(23):4139-50 |
1 | J:200565 Antony N, Weir JR, McDougall AR, Mantamadiotis T, Meikle PJ, Cole TJ, Bird AD, cAMP response element binding protein1 is essential for activation of steroyl co-enzyme a desaturase 1 (Scd1) in mouse lung type II epithelial cells. PLoS One. 2013;8(4):e59763 |
1 | J:89611 Asaki T, Konishi M, Miyake A, Kato S, Tomizawa M, Itoh N, Roles of fibroblast growth factor 10 (Fgf10) in adipogenesis in vivo. Mol Cell Endocrinol. 2004 Apr 15;218(1-2):119-28 |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
1 | J:267950 Holzman MA, Bergmann JM, Feldman M, Landry-Truchon K, Jeannotte L, Mansfield JH, HOXA5 protein expression and genetic fate mapping show lineage restriction in the developing musculoskeletal system. Int J Dev Biol. 2018;62(11-12):785-796 |
2* | J:239792 Hong KY, Bae H, Park I, Park DY, Kim KH, Kubota Y, Cho ES, Kim H, Adams RH, Yoo OJ, Koh GY, Perilipin+ embryonic preadipocytes actively proliferate along growing vasculatures for adipose expansion. Development. 2015 Aug 01;142(15):2623-32 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1* | J:189008 Jia Y, Viswakarma N, Crawford SE, Sarkar J, Sambasiva Rao M, Karpus WJ, Kanwar YS, Zhu YJ, Reddy JK, Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. Mech Dev. 2012 Sep;129(9-12):193-207 |
1 | J:342314 Jun S, Angueira AR, Fein EC, Tan JME, Weller AH, Cheng L, Batmanov K, Ishibashi J, Sakers AP, Stine RR, Seale P, Control of murine brown adipocyte development by GATA6. Dev Cell. 2023 Nov 6;58(21):2195-2205.e5 |
1* | J:19422 Kliewer SA, Forman BM, Blumberg B, Ong ES, Borgmeyer U, Mangelsdorf DJ, Umesono K, Evans RM, Differential expression and activation of a family of murine peroxisome proliferator-activated receptors. Proc Natl Acad Sci U S A. 1994 Jul 19;91(15):7355-9 |
1* | J:250161 Lee AJ, Polgar N, Napoli JA, Lui VH, Tamashiro KK, Fujimoto BA, Thompson KS, Fogelgren B, Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy. Sci Rep. 2016 Aug 11;6:31137 |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
2 | J:71272 Michalik L, Desvergne B, Tan NS, Basu-Modak S, Escher P, Rieusset J, Peters JM, Kaya G, Gonzalez FJ, Zakany J, Metzger D, Chambon P, Duboule D, Wahli W, Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice. J Cell Biol. 2001 Aug 20;154(4):799-814 |
1 | J:107381 Nadra K, Anghel SI, Joye E, Tan NS, Basu-Modak S, Trono D, Wahli W, Desvergne B, Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta. Mol Cell Biol. 2006 Apr;26(8):3266-81 |
1 | J:165668 Nadra K, Quignodon L, Sardella C, Joye E, Mucciolo A, Chrast R, Desvergne B, PPARgamma in placental angiogenesis. Endocrinology. 2010 Oct;151(10):4969-81 |
1 | J:341496 Veniaminova NA, Jia YY, Hartigan AM, Huyge TJ, Tsai SY, Grachtchouk M, Nakagawa S, Dlugosz AA, Atwood SX, Wong SY, Distinct mechanisms for sebaceous gland self-renewal and regeneration provide durability in response to injury. Cell Rep. 2023 Sep 26;42(9):113121 |
1 | J:216370 Wang W, Kissig M, Rajakumari S, Huang L, Lim HW, Won KJ, Seale P, Ebf2 is a selective marker of brown and beige adipogenic precursor cells. Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):14466-71 |
2 | J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26 |
1 | J:294983 Yao Y, Liu Q, Adrianto I, Wu X, Glassbrook J, Khalasawi N, Yin C, Yi Q, Dong Z, Geissmann F, Zhou L, Mi QS, Histone deacetylase 3 controls lung alveolar macrophage development and homeostasis. Nat Commun. 2020 Jul 30;11(1):3822 |
2* | J:236180 Zhou H, Black SM, Benson TW, Weintraub NL, Chen W, Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is Not Required for Brown Adipogenesis but Regulates Brown Adipose Tissue Development and Function. Mol Cell Biol. 2016 Aug 1;36(15):2027-38 |
Ppargc1a peroxisome proliferative activated receptor, gamma, coactivator 1 alpha (Synonyms: A830037N07Rik, Gm11133, Pgc1, Pgc-1alpha, Pgc-1alphaa, Pgco1, PPAR Gamma Coactivator-1) | |
Results | Reference |
1 | J:111407 Beaudry JB, Pierreux CE, Hayhurst GP, Plumb-Rudewiez N, Weiss MC, Rousseau GG, Lemaigre FP, Threshold levels of hepatocyte nuclear factor 6 (HNF-6) acting in synergy with HNF-4 and PGC-1alpha are required for time-specific gene expression during liver development. Mol Cell Biol. 2006 Aug;26(16):6037-46 |
1 | J:356661 Esteban-Martinez L, Sierra-Filardi E, McGreal RS, Salazar-Roa M, Marino G, Seco E, Durand S, Enot D, Grana O, Malumbres M, Cvekl A, Cuervo AM, Kroemer G, Boya P, Programmed mitophagy is essential for the glycolytic switch during cell differentiation. EMBO J. 2017 Jun 14;36(12):1688-1706 |
1 | J:324530 Fonseca TL, Russo SC, Luongo C, Salvatore D, Bianco AC, Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 May 1;163(5) |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
1* | J:65091 Lehman JJ, Barger PM, Kovacs A, Saffitz JE, Medeiros DM, Kelly DP, Peroxisome proliferator-activated receptor gamma coactivator-1 promotes cardiac mitochondrial biogenesis. J Clin Invest. 2000 Oct;106(7):847-56 |
Ppargc1b peroxisome proliferative activated receptor, gamma, coactivator 1 beta (Synonyms: 4631412G21Rik, PGC-1beta/ERRL1) | |
Results | Reference |
1 | J:324530 Fonseca TL, Russo SC, Luongo C, Salvatore D, Bianco AC, Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 May 1;163(5) |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
Ppbp pro-platelet basic protein (Synonyms: 2400003M24Rik, beta-TG, b-TG1, CTAP3, CTAPIII, Cxcl7, LA-PF4, LDGF, MDGF, NAP-2, NAP-2, NAP-2-L1, Scyb7, TGB, TGB1, THBGB1) | |
Results | Reference |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
Ppef1 protein phosphatase with EF hand calcium-binding domain 1 (Synonyms: Dres10, PPEF 1, PPEF-1) | |
Results | Reference |
1* | J:42890 Montini E, Rugarli EI, Van de Vosse E, Andolfi G, Mariani M, Puca AA , Consalez GG , den Dunnen JT , Ballabio A , Franco B, A novel human serine-threonine phosphatase related to the Drosophila retinal degeneration C (rdgC) gene is selectively expressed in sensory neurons of neural crest origin. Hum Mol Genet. 1997 Jul;6(7):1137-45 |
Ppfia1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 (Synonyms: C030014K08Rik, liprin, Liprin-alpha1, Liprin-alpha1a, Liprin-alpha1b) | |
Results | Reference |
1* | J:264159 Zurner M, Mittelstaedt T, tom Dieck S, Becker A, Schoch S, Analyses of the spatiotemporal expression and subcellular localization of liprin-alpha proteins. J Comp Neurol. 2011 Oct 15;519(15):3019-39 |
Ppfia2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 (Synonyms: E130120L08Rik, Liprin-alpha2) | |
Results | Reference |
1* | J:264159 Zurner M, Mittelstaedt T, tom Dieck S, Becker A, Schoch S, Analyses of the spatiotemporal expression and subcellular localization of liprin-alpha proteins. J Comp Neurol. 2011 Oct 15;519(15):3019-39 |
Ppfia3 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3 (Synonyms: 2410127E16Rik, Liprin-alpha3) | |
Results | Reference |
1* | J:264159 Zurner M, Mittelstaedt T, tom Dieck S, Becker A, Schoch S, Analyses of the spatiotemporal expression and subcellular localization of liprin-alpha proteins. J Comp Neurol. 2011 Oct 15;519(15):3019-39 |
Ppfia4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 (Synonyms: 1110008G13Rik, Gm3812, Liprin-alpha4, Liprin-alpha4a, Liprin-alpha4b, LOC100042382) | |
Results | Reference |
1* | J:264159 Zurner M, Mittelstaedt T, tom Dieck S, Becker A, Schoch S, Analyses of the spatiotemporal expression and subcellular localization of liprin-alpha proteins. J Comp Neurol. 2011 Oct 15;519(15):3019-39 |
Ppfibp2 PTPRF interacting protein, binding protein 2 (liprin beta 2) (Synonyms: Cclp1, liprin beta 2) | |
Results | Reference |
1* | J:40773 Noben-Trauth K, Naggert JK, Nishina PM, Cloning and expression analysis of mouse Cclp1, a new gene encoding a coiled-coil-like protein. Biochim Biophys Acta. 1997 May 30;1352(2):133-7 |
Ppia peptidylprolyl isomerase A (Synonyms: Cphn, cyclophilin A, CyP-18, CypA) | |
Results | Reference |
1* | J:85731 Spears N, Molinek MD, Robinson LL, Fulton N, Cameron H, Shimoda K, Telfer EE, Anderson RA, Price DJ, The role of neurotrophin receptors in female germ-cell survival in mouse and human. Development. 2003 Nov;130(22):5481-91 |
Ppid peptidylprolyl isomerase D (cyclophilin D) (Synonyms: 4930564J03Rik, cyclophilin 40, CYP-40, cytoplasmic cyclophilin D, Ppidl) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
Ppif peptidylprolyl isomerase F (cyclophilin F) (Synonyms: CypD, CyP-D, CyP-F, mitochondrial Cyclophilin D) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
Ppp1r1a protein phosphatase 1, regulatory inhibitor subunit 1A (Synonyms: 0610038N18Rik, I-1, inhibitor-1, protein phosphatase inhibitor-1) | |
Results | Reference |
1* | J:64301 McLaren L, Boyle S, Mason JO, Bard JB, Expression and genomic characterization of protein phosphatase inhibitor-1: a novel marker for mesothelium in the mouse. Mech Dev. 2000 Sep;96(2):237-41 |
Ppp1r1b protein phosphatase 1, regulatory inhibitor subunit 1B (Synonyms: Darpp32, DARPP-32) | |
Results | Reference |
1 | J:208050 Huang TN, Chuang HC, Chou WH, Chen CY, Wang HF, Chou SJ, Hsueh YP, Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality. Nat Neurosci. 2014 Feb;17(2):240-7 |
1 | J:134641 Liao WL, Tsai HC, Wang HF, Chang J, Lu KM, Wu HL, Lee YC, Tsai TF, Takahashi H, Wagner M, Ghyselinck NB, Chambon P, Liu FC, Modular patterning of structure and function of the striatum by retinoid receptor signaling. Proc Natl Acad Sci U S A. 2008 May 6;105(18):6765-70 |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
Ppp1r3b protein phosphatase 1, regulatory subunit 3B (Synonyms: GL) | |
Results | Reference |
1* | J:132397 Cifuentes D, Martinez-Pons C, Garcia-Rocha M, Galina A, de Pouplana LR, Guinovart JJ, Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver. J Biol Chem. 2008 Feb 29;283(9):5642-9 |
3* | J:113028 Niimi T, Kurotani R, Kimura S, Kitagawa Y, Identification and expression of alternative splice variants of the mouse Ppp1r3b gene in lung epithelial cells. Biochem Biophys Res Commun. 2006 Oct 20;349(2):588-96 |
Ppp1r3c protein phosphatase 1, regulatory subunit 3C (Synonyms: Ppp1r5, protein targeting to glicogen, PTG) | |
Results | Reference |
1* | J:132397 Cifuentes D, Martinez-Pons C, Garcia-Rocha M, Galina A, de Pouplana LR, Guinovart JJ, Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver. J Biol Chem. 2008 Feb 29;283(9):5642-9 |
Ppp1r12a protein phosphatase 1, regulatory subunit 12A (Synonyms: 1200015F06Rik, 5730577I22Rik, D10Ertd625e, Mypt1) | |
Results | Reference |
1 | J:167714 Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, Chen H, Haneline LS, Chan RJ, Schwartz RJ, Field LJ, Atkinson SJ, Shou W, Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development. 2011 Jan;138(2):303-15 |
Ppp1r13b protein phosphatase 1, regulatory subunit 13B (Synonyms: ASPP1) | |
Results | Reference |
1 | J:92259 Hirashima M, Bernstein A, Stanford WL, Rossant J, Gene-trap expression screening to identify endothelial-specific genes. Blood. 2004 Aug 1;104(3):711-8 |
Ppp1r13l protein phosphatase 1, regulatory subunit 13 like (Synonyms: IASPP, NFkB interacting protein 1, wa3) | |
Results | Reference |
1* | J:190557 Toonen J, Liang L, Sidjanin DJ, Waved with open eyelids 2 (woe2) is a novel spontaneous mouse mutation in the protein phosphatase 1, regulatory (inhibitor) subunit 13 like (Ppp1r13l) gene. BMC Genet. 2012;13:76 |
Ppp1r15a protein phosphatase 1, regulatory subunit 15A (Synonyms: Gadd34, Myd116) | |
Results | Reference |
1* | J:110590 Kojima E, Takeuchi A, Haneda M, Yagi A, Hasegawa T, Yamaki K, Takeda K, Akira S, Shimokata K, Isobe K, The function of GADD34 is a recovery from a shutoff of protein synthesis induced by ER stress: elucidation by GADD34-deficient mice. FASEB J. 2003 Aug;17(11):1573-5 |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
Ppp1r17 protein phosphatase 1, regulatory subunit 17 (Synonyms: Gsbs, G-substrate) | |
Results | Reference |
1* | J:329049 Galdos FX, Xu S, Goodyer WR, Duan L, Huang YV, Lee S, Zhu H, Lee C, Wei N, Lee D, Wu SM, devCellPy is a machine learning-enabled pipeline for automated annotation of complex multilayered single-cell transcriptomic data. Nat Commun. 2022 Sep 7;13(1):5271 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
Ppp2ca protein phosphatase 2 (formerly 2A), catalytic subunit, alpha isoform (Synonyms: PP2A) | |
Results | Reference |
1 | J:346063 Rehmani T, Dias AP, Kamal M, Salih M, Tuana BS, Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway. Int J Mol Sci. 2024 Mar 1;25(5) |
Ppp2cb protein phosphatase 2 (formerly 2A), catalytic subunit, beta isoform (Synonyms: D8Ertd766e, PP2Ac) | |
Results | Reference |
1 | J:346063 Rehmani T, Dias AP, Kamal M, Salih M, Tuana BS, Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway. Int J Mol Sci. 2024 Mar 1;25(5) |
Ppp2r1a protein phosphatase 2, regulatory subunit A, alpha (Synonyms: 6330556D22Rik, PP2A, PR65, protein phosphatase PP2A) | |
Results | Reference |
1 | J:346063 Rehmani T, Dias AP, Kamal M, Salih M, Tuana BS, Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway. Int J Mol Sci. 2024 Mar 1;25(5) |
Ppp2r2a protein phosphatase 2, regulatory subunit B, alpha (Synonyms: 2410004D02Rik) | |
Results | Reference |
2 | J:153617 O'Shaughnessy RF, Welti JC, Sully K, Byrne C, Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development. Development. 2009 Oct;136(20):3423-31 |
1 | J:199582 Youssef G, Gerner L, Naeem AS, Ralph O, Ono M, O'Neill CA, O'Shaughnessy RF, Rab3Gap1 mediates exocytosis of Claudin-1 and tight junction formation during epidermal barrier acquisition. Dev Biol. 2013 Aug 15;380(2):274-85 |
Ppp2r2b protein phosphatase 2, regulatory subunit B, beta (Synonyms: 2900026H06Rik, 6330404L05Rik, E130009M08Rik, PP2A-PR55B, PR55-BETA, SCA12) | |
Results | Reference |
1 | J:153617 O'Shaughnessy RF, Welti JC, Sully K, Byrne C, Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development. Development. 2009 Oct;136(20):3423-31 |
Ppp2r2c protein phosphatase 2, regulatory subunit B, gamma (Synonyms: 6330548O06Rik, IMYPNO1, PR52) | |
Results | Reference |
1 | J:153617 O'Shaughnessy RF, Welti JC, Sully K, Byrne C, Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development. Development. 2009 Oct;136(20):3423-31 |
Ppp2r2d protein phosphatase 2, regulatory subunit B, delta (Synonyms: 1300017E19Rik, D7Ertd753e, MDS026, mKIAA1541) | |
Results | Reference |
1 | J:153617 O'Shaughnessy RF, Welti JC, Sully K, Byrne C, Akt-dependent Pp2a activity is required for epidermal barrier formation during late embryonic development. Development. 2009 Oct;136(20):3423-31 |
Ppp2r5b protein phosphatase 2, regulatory subunit B', beta (Synonyms: B'beta) | |
Results | Reference |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
Ppp2r5c protein phosphatase 2, regulatory subunit B', gamma (Synonyms: 2610043M05Rik, 2700063L20Rik, B56/PP2A gamma, Band 8A, D12Bwg0916e, mKIAA0044) | |
Results | Reference |
2* | J:105770 Tierling S, Dalbert S, Schoppenhorst S, Tsai CE, Oliger S, Ferguson-Smith AC, Paulsen M, Walter J, High-resolution map and imprinting analysis of the Gtl2-Dnchc1 domain on mouse chromosome 12. Genomics. 2006 Feb;87(2):225-35 |
Ppp3ca protein phosphatase 3, catalytic subunit, alpha isoform (Synonyms: 2900074D19Rik, Caln, Calna, CN, CnA, PP2BA alpha, PP2B alpha 1) | |
Results | Reference |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Ppp3cb protein phosphatase 3, catalytic subunit, beta isoform (Synonyms: 1110063J16Rik, Calnb, Cnab, CnAbeta, PP2BA beta) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Ppp3r1 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) (Synonyms: CaNB1, Cnb1, PP2B beta 1) | |
Results | Reference |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Ppp3r2 protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type II) (Synonyms: CaNB2, CnB2, PP2B beta 2) | |
Results | Reference |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Ppp6r2 protein phosphatase 6, regulatory subunit 2 (Synonyms: 1110033O10Rik, 8430411H09Rik, B230107H12Rik, Pp6r2, Saps2) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Ppy pancreatic polypeptide (Synonyms: IGSPP, PP) | |
Results | Reference |
1 | J:156329 Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L, Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. J Biol Chem. 2009 Nov 6;284(45):31236-48 |
1* | J:22553 Guz Y, Montminy MR, Stein R, Leonard J, Gamer LW, Wright CV, Teitelman G, Expression of murine STF-1, a putative insulin gene transcription factor, in beta cells of pancreas, duodenal epithelium and pancreatic exocrine and endocrine progenitors during ontogeny. Development. 1995 Jan;121(1):11-8 |
1* | J:1922 Herrera PL, Huarte J, Sanvito F, Meda P, Orci L, Vassalli JD, Embryogenesis of the murine endocrine pancreas; early expression of pancreatic polypeptide gene. Development. 1991 Dec;113(4):1257-65 |
1 | J:35196 Jackerott M, Oster A, Larsson LI, PYY in developing murine islet cells: comparisons to development of islet hormones, NPY, and BrdU incorporation. J Histochem Cytochem. 1996 Aug;44(8):809-17 |
1 | J:62160 Miettinen PJ, Huotari M, Koivisto T, Ustinov J, Palgi J, Rasilainen S, Lehtonen E, Keski-Oja J, Otonkoski T, Impaired migration and delayed differentiation of pancreatic islet cells in mice lacking EGF-receptors. Development. 2000 Jun;127(12):2617-27 |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
1 | J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461 |
1 | J:239946 Pan FC, Brissova M, Powers AC, Pfaff S, Wright CV, Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing beta-cells to a delta-like fate and reveals a facultative proliferative capacity in aged beta-cells. Development. 2015 Nov 01;142(21):3637-48 |
1 | J:147764 Svensson P, Bergqvist I, Norlin S, Edlund H, MFng is dispensable for mouse pancreas development and function. Mol Cell Biol. 2009 Apr;29(8):2129-38 |
Prag1 PEAK1 related kinase activating pseudokinase 1 (Synonyms: D8Ertd82e, NACK) | |
Results | Reference |
1* | J:214228 Weaver KL, Alves-Guerra MC, Jin K, Wang Z, Han X, Ranganathan P, Zhu X, DaSilva T, Liu W, Ratti F, Demarest RM, Tzimas C, Rice M, Vasquez-Del Carpio R, Dahmane N, Robbins DJ, Capobianco AJ, NACK is an integral component of the Notch transcriptional activation complex and is critical for development and tumorigenesis. Cancer Res. 2014 Sep 1;74(17):4741-51 |
Prb1a proline-rich protein BstNI subfamily 1A (Synonyms: Prb1, proline-rich proteoglycan 2) | |
Results | Reference |
1 | J:205334 Saba R, Kato Y, Saga Y, NANOS2 promotes male germ cell development independent of meiosis suppression. Dev Biol. 2014 Jan 1;385(1):32-40 |
Prdm1 PR domain containing 1, with ZNF domain (Synonyms: b2b1765Clo, Blimp-1, Blimp1, PRDI-BF1) | |
Results | Reference |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:304642 Dupacova N, Antosova B, Paces J, Kozmik Z, Meis homeobox genes control progenitor competence in the retina. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2013136118 |
1* | J:178994 Fantauzzo KA, Christiano AM, Trps1 activates a network of secreted Wnt inhibitors and transcription factors crucial to vibrissa follicle morphogenesis. Development. 2012 Jan;139(1):203-14 |
1 | J:356109 Ge W, Tan SJ, Wang SH, Li L, Sun XF, Shen W, Wang X, Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development. Theranostics. 2020;10(17):7581-7598 |
1 | J:223559 Goetz JJ, Martin GM, Chowdhury R, Trimarchi JM, Onecut1 and Onecut2 play critical roles in the development of the mouse retina. PLoS One. 2014;9(10):e110194 |
2 | J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90 |
2* | J:202344 Lesko MH, Driskell RR, Kretzschmar K, Goldie SJ, Watt FM, Sox2 modulates the function of two distinct cell lineages in mouse skin. Dev Biol. 2013 Oct 1;382(1):15-26 |
1 | J:285747 Liu S, Liu X, Li S, Huang X, Qian H, Jin K, Xiang M, Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5016-5027 |
1 | J:253178 Mitani T, Yabuta Y, Ohta H, Nakamura T, Yamashiro C, Yamamoto T, Saitou M, Kurimoto K, Principles for the regulation of multiple developmental pathways by a versatile transcriptional factor, BLIMP1. Nucleic Acids Res. 2017 Dec 1;45(21):12152-12169 |
Prdm2 PR domain containing 2, with ZNF domain (Synonyms: 4833427P12Rik, E330024L24Rik, KMT8, LOC381568, Riz, Riz1) | |
Results | Reference |
2* | J:194983 Ideno H, Shimada A, Imaizumi K, Kimura H, Abe M, Nakashima K, Nifuji A, Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development. Gene Expr Patterns. 2013 Mar-Apr;13(3-4):84-90 |
1* | J:320688 Wada S, Ideno H, Shimada A, Kamiunten T, Nakamura Y, Nakashima K, Kimura H, Shinkai Y, Tachibana M, Nifuji A, H3K9MTase G9a is essential for the differentiation and growth of tenocytes in vitro. Histochem Cell Biol. 2015 Jul;144(1):13-20 |
Prdm5 PR domain containing 5 (Synonyms: 4432417F03Rik, 6530401I24Rik, E130112L17Rik, PFM2) | |
Results | Reference |
1 | J:185118 Galli GG, Honnens de Lichtenberg K, Carrara M, Hans W, Wuelling M, Mentz B, Multhaupt HA, Fog CK, Jensen KT, Rappsilber J, Vortkamp A, Coulton L, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Calogero RA, Couchman JR, Lund AH, Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone. PLoS Genet. 2012 May;8(5):e1002711 |
Prdm6 PR domain containing 6 (Synonyms: LOC225518, PRISM) | |
Results | Reference |
1 | J:209773 Gewies A, Castineiras-Vilarino M, Ferch U, Jahrling N, Heinrich K, Hoeckendorf U, Przemeck GK, Munding M, Gross O, Schroeder T, Horsch M, Karran EL, Majid A, Antonowicz S, Beckers J, Hrabe de Angelis M, Dodt HU, Peschel C, Forster I, Dyer MJ, Ruland J, Prdm6 is essential for cardiovascular development in vivo. PLoS One. 2013;8(11):e81833 |
Prdm8 PR domain containing 8 | |
Results | Reference |
1* | J:144373 Kinameri E, Inoue T, Aruga J, Imayoshi I, Kageyama R, Shimogori T, Moore AW, Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. PLoS One. 2008;3(12):e3859 |
1* | J:152410 Komai T, Iwanari H, Mochizuki Y, Hamakubo T, Shinkai Y, Expression of the mouse PR domain protein Prdm8 in the developing central nervous system. Gene Expr Patterns. 2009 Oct;9(7):503-14 |
2 | J:182304 Ross SE, McCord AE, Jung C, Atan D, Mok SI, Hemberg M, Kim TK, Salogiannis J, Hu L, Cohen S, Lin Y, Harrar D, McInnes RR, Greenberg ME, Bhlhb5 and Prdm8 form a repressor complex involved in neuronal circuit assembly. Neuron. 2012 Jan 26;73(2):292-303 |
Prdm9 PR domain containing 9 (Synonyms: Dsbc1, G1-419-29, Meisetz, MGC:21428, Rcr1, repro7) | |
Results | Reference |
1* | J:102875 Hayashi K, Yoshida K, Matsui Y, A histone H3 methyltransferase controls epigenetic events required for meiotic prophase. Nature. 2005 Nov 17;438(7066):374-8 |
Prdm10 PR domain containing 10 (Synonyms: LOC382066, MGC:73898, tristanin) | |
Results | Reference |
1* | J:161571 Park JA, Kim KC, Expression patterns of PRDM10 during mouse embryonic development. BMB Rep. 2010 Jan;43(1):29-33 |
Prdm12 PR domain containing 12 (Synonyms: LOC381359) | |
Results | Reference |
1 | J:283226 Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld KA, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ, Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA. Cell Rep. 2019 Mar 26;26(13):3522-3536.e5 |
1* | J:144373 Kinameri E, Inoue T, Aruga J, Imayoshi I, Kageyama R, Shimogori T, Moore AW, Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. PLoS One. 2008;3(12):e3859 |
Prdm13 PR domain containing 13 | |
Results | Reference |
1* | J:197142 Chang JC, Meredith DM, Mayer PR, Borromeo MD, Lai HC, Ou YH, Johnson JE, Prdm13 mediates the balance of inhibitory and excitatory neurons in somatosensory circuits. Dev Cell. 2013 Apr 29;25(2):182-95 |
1 | J:316423 Whittaker DE, Oleari R, Gregory LC, Le Quesne-Stabej P, Williams HJ, Torpiano JG, Formosa N, Cachia MJ, Field D, Lettieri A, Ocaka LA, Paganoni AJ, Rajabali SH, Riegman KL, De Martini LB, Chaya T, Robinson IC, Furukawa T, Cariboni A, Basson MA, Dattani MT, A recessive PRDM13 mutation results in congenital hypogonadotropic hypogonadism and cerebellar hypoplasia. J Clin Invest. 2021 Dec 15;131(24):e141587 |
1 | J:354849 Wutikeli H, Yu Y, Zhang T, Cao J, Nawy S, Shen Y, Role of Elavl-like RNA-binding protein in retinal development and signal transduction. Biochim Biophys Acta Mol Basis Dis. 2024 Sep 20;1871(1):167518 |
Prdm14 PR domain containing 14 | |
Results | Reference |
2* | J:143899 Dettman EJ, Justice MJ, The zinc finger SET domain gene Prdm14 is overexpressed in lymphoblastic lymphomas with retroviral insertions at Evi32. PLoS One. 2008;3(11):e3823 |
Prdm16 PR domain containing 16 (Synonyms: 5730557K01Rik, csp1, line 27, Mel1) | |
Results | Reference |
1* | J:330213 Ebeid M, Barnas K, Zhang H, Yaghmour A, Noreikaite G, Bjork BC, PRDM16 expression and function in mammalian cochlear development. Dev Dyn. 2022 Oct;251(10):1666-1683 |
1 | J:324530 Fonseca TL, Russo SC, Luongo C, Salvatore D, Bianco AC, Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 May 1;163(5) |
1 | J:254641 Groman-Lupa S, Adewumi J, Park KU, Brzezinski Iv JA, The Transcription Factor Prdm16 Marks a Single Retinal Ganglion Cell Subtype in the Mouse Retina. Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5421-5433 |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
2 | J:354192 He H, Bell SM, Davis AK, Zhao S, Sridharan A, Na CL, Guo M, Xu Y, Snowball J, Swarr DT, Zacharias WJ, Whitsett JA, PRDM3/16 regulate chromatin accessibility required for NKX2-1 mediated alveolar epithelial differentiation and function. Nat Commun. 2024 Sep 16;15(1):8112 |
1* | J:239166 Inoue M, Iwai R, Tabata H, Konno D, Komabayashi-Suzuki M, Watanabe C, Iwanari H, Mochizuki Y, Hamakubo T, Matsuzaki F, Nagata KI, Mizutani KI, Prdm16 is crucial for progression of the multipolar phase during neural differentiation of the developing neocortex. Development. 2017 Feb 01;144(3):385-399 |
1* | J:144373 Kinameri E, Inoue T, Aruga J, Imayoshi I, Kageyama R, Shimogori T, Moore AW, Prdm proto-oncogene transcription factor family expression and interaction with the Notch-Hes pathway in mouse neurogenesis. PLoS One. 2008;3(12):e3859 |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
1* | J:236180 Zhou H, Black SM, Benson TW, Weintraub NL, Chen W, Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is Not Required for Brown Adipogenesis but Regulates Brown Adipose Tissue Development and Function. Mol Cell Biol. 2016 Aug 1;36(15):2027-38 |
Prdx1 peroxiredoxin 1 (Synonyms: macrophage 23kDa stress protein, macrophase stress protein 22kDa, MSP23, OSF-3, osteoblast specific factor 3, PAG, Paga, prx1, Prx I, PrxI, Tdpx2, TDX2, thioredoxin dependent peroxide reductase 2, Trx dependent peroxide reductase 2) | |
Results | Reference |
1* | J:191045 Huebner AJ, Dai D, Morasso M, Schmidt EE, Schafer M, Werner S, Roop DR, Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero. Dev Cell. 2012 Dec 11;23(6):1238-46 |
1* | J:227089 Pirson M, Knoops B, Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617 |
Prdx2 peroxiredoxin 2 (Synonyms: protector protein, PRP, PrxII, Prx II-1, Tdpx1, TDX1, thiol specific antioxidant protein, thioredoxin dependent peroxide reductase 1, thioredoxin peroxidase, thioredoxin reductase, TPx, TR, Trx dependent peroxide reductase 1, TSA) | |
Results | Reference |
1* | J:227089 Pirson M, Knoops B, Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617 |
Prdx3 peroxiredoxin 3 (Synonyms: Aop1, D0Tohi1, Ef2l, Mer5, Prx III, SP22, TDXM) | |
Results | Reference |
1* | J:227089 Pirson M, Knoops B, Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617 |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
Prdx4 peroxiredoxin 4 (Synonyms: AOE372, Prx4, Prx-iv, Prx IV) | |
Results | Reference |
1* | J:227089 Pirson M, Knoops B, Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617 |
Prdx5 peroxiredoxin 5 (Synonyms: AOEB166, AOPP, peroxiredoxin V, PMP20, Prdx6, PrxV, PrxV) | |
Results | Reference |
1* | J:227089 Pirson M, Knoops B, Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617 |
Prdx6 peroxiredoxin 6 (Synonyms: 1-cysPrx, 1-Cys Prx, 9430088D19Rik, acidic calcium-independent phospholipase A2, aiPLA2, Aop2, Brp-12, CC26, CP-3, GPx, Ltw-4, Ltw4, Lvtw-4, NSGP) | |
Results | Reference |
1* | J:227089 Pirson M, Knoops B, Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617 |
Preb prolactin regulatory element binding | |
Results | Reference |
1* | J:60870 Taylor Clelland CL, Craciun L, Bancroft C, Lufkin T, Mapping and developmental expression analysis of the WD-repeat gene preb. Genomics. 2000 Feb 1;63(3):391-9 |
Prep prolyl endopeptidase (Synonyms: D10Wsu136e, Pop, prolyl oligopeptidase) | |
Results | Reference |
1 | J:162687 Matsubara S, Takahashi T, Kimura AP, Epigenetic patterns at the mouse prolyl oligopeptidase gene locus suggest the CpG island in the gene body to be a novel regulator for gene expression. Gene. 2010 Oct 1;465(1-2):17-29 |
3 | J:174102 Matsubara S, Takahashi T, Kimura AP, Localization and subcellular distribution of prolyl oligopeptidase in the mouse placenta. J Mol Histol. 2011 Jun;42(3):251-64 |
Prg2 proteoglycan 2, bone marrow (Synonyms: EMBP, mMBP, mMBP-1) | |
Results | Reference |
1 | J:295421 Brosig A, Fuchs J, Ipek F, Kroon C, Schrotter S, Vadhvani M, Polyzou A, Ledderose J, van Diepen M, Holzhutter HG, Trimbuch T, Gimber N, Schmoranzer J, Lieberam I, Rosenmund C, Spahn C, Scheerer P, Szczepek M, Leondaritis G, Eickholt BJ, The Axonal Membrane Protein PRG2 Inhibits PTEN and Directs Growth to Branches. Cell Rep. 2019 Nov 12;29(7):2028-2040.e8 |
Prg4 proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein) (Synonyms: DOL54, lubricin, MSF, SZP) | |
Results | Reference |
1 | J:148688 Kahn J, Shwartz Y, Blitz E, Krief S, Sharir A, Breitel DA, Rattenbach R, Relaix F, Maire P, Rountree RB, Kingsley DM, Zelzer E, Muscle contraction is necessary to maintain joint progenitor cell fate. Dev Cell. 2009 May;16(5):734-43 |
1 | J:194035 Kan A, Tabin CJ, c-Jun is required for the specification of joint cell fates. Genes Dev. 2013 Mar 1;27(5):514-24 |
1* | J:326033 Kim M, Koyama E, Saunders CM, Querido W, Pleshko N, Pacifici M, Synovial joint cavitation initiates with microcavities in interzone and is coupled to skeletal flexion and elongation in developing mouse embryo limbs. Biol Open. 2022 Jun 15;11(6):bio059381 |
1 | J:170582 Mundy C, Yasuda T, Kinumatsu T, Yamaguchi Y, Iwamoto M, Enomoto-Iwamoto M, Koyama E, Pacifici M, Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine. Dev Biol. 2011 Mar 1;351(1):70-81 |
1 | J:96756 Rhee DK, Marcelino J, Baker M, Gong Y, Smits P, Lefebvre V, Jay GD, Stewart M, Wang H, Warman ML, Carpten JD, The secreted glycoprotein lubricin protects cartilage surfaces and inhibits synovial cell overgrowth. J Clin Invest. 2005 Mar;115(3):622-31 |
Prickle1 prickle planar cell polarity protein 1 (Synonyms: 1110058P22Rik, b2b019Clo, mpk1, Pk1) | |
Results | Reference |
1 | J:301041 Guo D, Ru J, Mao F, Ouyang H, Ju R, Wu K, Liu Y, Liu C, Ontogenesis of the tear drainage system requires Prickle1-driven polarized basement membrane deposition. Development. 2020 Nov 30;147(22):dev191726 |
1 | J:329316 Kunimoto K, Weiner AT, Axelrod JD, Vladar EK, Distinct overlapping functions for Prickle1 and Prickle2 in the polarization of the airway epithelium. Front Cell Dev Biol. 2022;10:976182 |
1 | J:198157 Liu C, Lin C, Whitaker DT, Bakeri H, Bulgakov OV, Liu P, Lei J, Dong L, Li T, Swaroop A, Prickle1 is expressed in distinct cell populations of the central nervous system and contributes to neuronal morphogenesis. Hum Mol Genet. 2013 Jun 1;22(11):2234-46 |
1 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
2* | J:126805 Okuda H, Miyata S, Mori Y, Tohyama M, Mouse Prickle1 and Prickle2 are expressed in postmitotic neurons and promote neurite outgrowth. FEBS Lett. 2007 Oct 2;581(24):4754-60 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Prickle2 prickle planar cell polarity protein 2 (Synonyms: 6230400G14Rik, 6720451F06Rik, mpk2, Pk2) | |
Results | Reference |
1 | J:119451 Deans MR, Antic D, Suyama K, Scott MP, Axelrod JD, Goodrich LV, Asymmetric distribution of Prickle-like 2 reveals an early underlying polarization of vestibular sensory epithelia in the inner ear. J Neurosci. 2007 Mar 21;27(12):3139-47 |
1 | J:329316 Kunimoto K, Weiner AT, Axelrod JD, Vladar EK, Distinct overlapping functions for Prickle1 and Prickle2 in the polarization of the airway epithelium. Front Cell Dev Biol. 2022;10:976182 |
2* | J:126805 Okuda H, Miyata S, Mori Y, Tohyama M, Mouse Prickle1 and Prickle2 are expressed in postmitotic neurons and promote neurite outgrowth. FEBS Lett. 2007 Oct 2;581(24):4754-60 |
Prkaa1 protein kinase, AMP-activated, alpha 1 catalytic subunit (Synonyms: AMPKalpha1, C130083N04Rik) | |
Results | Reference |
2 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1* | J:305946 Xu M, Yao J, Shi Y, Yi H, Zhao W, Lin X, Yang Z, The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026 |
Prkaa2 protein kinase, AMP-activated, alpha 2 catalytic subunit (Synonyms: 2310008I11Rik, AMPKalpha2) | |
Results | Reference |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1* | J:305946 Xu M, Yao J, Shi Y, Yi H, Zhao W, Lin X, Yang Z, The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026 |
Prkab1 protein kinase, AMP-activated, beta 1 non-catalytic subunit (Synonyms: 1300015D22Rik) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1 | J:280538 Yeganeh B, Lee J, Ermini L, Lok I, Ackerley C, Post M, Autophagy is required for lung development and morphogenesis. J Clin Invest. 2019 Jun 4;129(7):2904-2919 |
Prkab2 protein kinase, AMP-activated, beta 2 non-catalytic subunit (Synonyms: 5730553K21Rik) | |
Results | Reference |
1 | J:280538 Yeganeh B, Lee J, Ermini L, Lok I, Ackerley C, Post M, Autophagy is required for lung development and morphogenesis. J Clin Invest. 2019 Jun 4;129(7):2904-2919 |
Prkaca protein kinase, cAMP dependent, catalytic, alpha (Synonyms: C alpha, Cs, PKA, Pkaca) | |
Results | Reference |
1* | J:35122 Imaizumi-Scherrer T, Faust DM, Benichou JC, Hellio R, Weiss MC, Accumulation in fetal muscle and localization to the neuromuscular junction of cAMP-dependent protein kinase A regulatory and catalytic subunits RI alpha and C alpha. J Cell Biol. 1996 Sep;134(5):1241-54 |
Prkag1 protein kinase, AMP-activated, gamma 1 non-catalytic subunit (Synonyms: Prkaac) | |
Results | Reference |
1* | J:186631 Pinter K, Grignani RT, Czibik G, Farza H, Watkins H, Redwood C, Embryonic expression of AMPK gamma subunits and the identification of a novel gamma2 transcript variant in adult heart. J Mol Cell Cardiol. 2012 Sep;53(3):342-9 |
Prkag2 protein kinase, AMP-activated, gamma 2 non-catalytic subunit (Synonyms: 2410051C13Rik) | |
Results | Reference |
1* | J:186631 Pinter K, Grignani RT, Czibik G, Farza H, Watkins H, Redwood C, Embryonic expression of AMPK gamma subunits and the identification of a novel gamma2 transcript variant in adult heart. J Mol Cell Cardiol. 2012 Sep;53(3):342-9 |
Prkag3 protein kinase, AMP-activated, gamma 3 non-catalytic subunit (Synonyms: AMPKg3, AMPKg3L, AMPKg3S) | |
Results | Reference |
1* | J:186631 Pinter K, Grignani RT, Czibik G, Farza H, Watkins H, Redwood C, Embryonic expression of AMPK gamma subunits and the identification of a novel gamma2 transcript variant in adult heart. J Mol Cell Cardiol. 2012 Sep;53(3):342-9 |
Prkar1a protein kinase, cAMP dependent regulatory, type I, alpha (Synonyms: 1300018C22Rik, RIalpha, Tse-1, Tse1) | |
Results | Reference |
1* | J:35122 Imaizumi-Scherrer T, Faust DM, Benichou JC, Hellio R, Weiss MC, Accumulation in fetal muscle and localization to the neuromuscular junction of cAMP-dependent protein kinase A regulatory and catalytic subunits RI alpha and C alpha. J Cell Biol. 1996 Sep;134(5):1241-54 |
Prkar2a protein kinase, cAMP dependent regulatory, type II alpha (Synonyms: 1110061A24Rik, RII(alpha)) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
Prkca protein kinase C, alpha (Synonyms: Pkca) | |
Results | Reference |
1* | J:332849 Baskaran P, Mihaylov SR, Vinsland E, Shah K, Granat L, Ultanir SK, Tee AR, Murn J, Bateman JM, Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis. J Biol Chem. 2023 Jan;299(1):102788 |
1* | J:87315 Cogram P, Hynes A, Dunlevy LP, Greene ND, Copp AJ, Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol. Hum Mol Genet. 2004 Jan 1;13(1):7-14 |
1 | J:172287 Esteve P, Sandonis A, Cardozo M, Malapeira J, Ibanez C, Crespo I, Marcos S, Gonzalez-Garcia S, Toribio ML, Arribas J, Shimono A, Guerrero I, Bovolenta P, SFRPs act as negative modulators of ADAM10 to regulate retinal neurogenesis. Nat Neurosci. 2011 May;14(5):562-9 |
1 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
1* | J:83700 Koyama N, Kashimata M, Sakashita H, Sakagami H, Gresik EW, EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland. Dev Dyn. 2003 Jun;227(2):216-26 |
1 | J:108702 Zhang CL, Zou Y, Yu RT, Gage FH, Evans RM, Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes Dev. 2006 May 15;20(10):1308-20 |
Prkcb protein kinase C, beta (Synonyms: A130082F03Rik, Pkcb, PKC-Beta, Prkcb1, Prkcb2) | |
Results | Reference |
1* | J:87315 Cogram P, Hynes A, Dunlevy LP, Greene ND, Copp AJ, Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol. Hum Mol Genet. 2004 Jan 1;13(1):7-14 |
1* | J:83700 Koyama N, Kashimata M, Sakashita H, Sakagami H, Gresik EW, EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland. Dev Dyn. 2003 Jun;227(2):216-26 |
Prkcd protein kinase C, delta (Synonyms: D14Ertd420e, Pkcd, PKC[d], PKCdelta) | |
Results | Reference |
1 | J:87315 Cogram P, Hynes A, Dunlevy LP, Greene ND, Copp AJ, Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol. Hum Mol Genet. 2004 Jan 1;13(1):7-14 |
1* | J:83700 Koyama N, Kashimata M, Sakashita H, Sakagami H, Gresik EW, EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland. Dev Dyn. 2003 Jun;227(2):216-26 |
Prkce protein kinase C, epsilon (Synonyms: 5830406C15Rik, PCK epsilon, Pkce, PKC[e], PKCepsilon) | |
Results | Reference |
1* | J:87315 Cogram P, Hynes A, Dunlevy LP, Greene ND, Copp AJ, Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol. Hum Mol Genet. 2004 Jan 1;13(1):7-14 |
1* | J:83700 Koyama N, Kashimata M, Sakashita H, Sakagami H, Gresik EW, EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland. Dev Dyn. 2003 Jun;227(2):216-26 |
Prkcg protein kinase C, gamma (Synonyms: Pkcc, PKCgamma, Prkcc) | |
Results | Reference |
1* | J:87315 Cogram P, Hynes A, Dunlevy LP, Greene ND, Copp AJ, Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol. Hum Mol Genet. 2004 Jan 1;13(1):7-14 |
1* | J:83700 Koyama N, Kashimata M, Sakashita H, Sakagami H, Gresik EW, EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland. Dev Dyn. 2003 Jun;227(2):216-26 |
Prkch protein kinase C, eta (Synonyms: Pkch) | |
Results | Reference |
1 | J:87315 Cogram P, Hynes A, Dunlevy LP, Greene ND, Copp AJ, Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol. Hum Mol Genet. 2004 Jan 1;13(1):7-14 |
1* | J:83700 Koyama N, Kashimata M, Sakashita H, Sakagami H, Gresik EW, EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland. Dev Dyn. 2003 Jun;227(2):216-26 |
Prkci protein kinase C, iota (Synonyms: 2310021H13Rik, aPKClambda, Pkci, Pkcl, PKClambda, Prkcl) | |
Results | Reference |
1 | J:87315 Cogram P, Hynes A, Dunlevy LP, Greene ND, Copp AJ, Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol. Hum Mol Genet. 2004 Jan 1;13(1):7-14 |
1 | J:130194 Costa MR, Wen G, Lepier A, Schroeder T, Gotz M, Par-complex proteins promote proliferative progenitor divisions in the developing mouse cerebral cortex. Development. 2008 Jan;135(1):11-22 |
1 | J:178336 Grosse AS, Pressprich MF, Curley LB, Hamilton KL, Margolis B, Hildebrand JD, Gumucio DL, Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis. Development. 2011 Oct;138(20):4423-32 |
1 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
1 | J:140256 Hartleben B, Schweizer H, Lubben P, Bartram MP, Moller CC, Herr R, Wei C, Neumann-Haefelin E, Schermer B, Zentgraf H, Kerjaschki D, Reiser J, Walz G, Benzing T, Huber TB, Neph-Nephrin proteins bind the Par3-Par6-atypical protein kinase C (aPKC) complex to regulate podocyte cell polarity. J Biol Chem. 2008 Aug 22;283(34):23033-8 |
1* | J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347 |
1* | J:220858 Kim JY, Song JY, Karnam S, Park JY, Lee JJ, Kim S, Cho SH, Common and distinctive localization patterns of Crumbs polarity complex proteins in the mammalian eye. Gene Expr Patterns. 2015 Jan;17(1):31-7 |
1* | J:115984 Kovac J, Oster H, Leitges M, Expression of the atypical protein kinase C (aPKC) isoforms iota/lambda and zeta during mouse embryogenesis. Gene Expr Patterns. 2007 Jan;7(1-2):187-196 |
1* | J:83700 Koyama N, Kashimata M, Sakashita H, Sakagami H, Gresik EW, EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland. Dev Dyn. 2003 Jun;227(2):216-26 |
1 | J:273200 Landin Malt A, Dailey Z, Holbrook-Rasmussen J, Zheng Y, Hogan A, Du Q, Lu X, Par3 is essential for the establishment of planar cell polarity of inner ear hair cells. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4999-5008 |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
2 | J:213479 Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, Yoshida N, PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Cereb Cortex. 2013 Aug;23(8):1824-35 |
1 | J:154910 Sugiyama Y, Akimoto K, Robinson ML, Ohno S, Quinlan RA, A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol. 2009 Dec 15;336(2):246-56 |
1 | J:139368 Wang G, Krishnamurthy K, Chiang YW, Dasgupta S, Bieberich E, Regulation of neural progenitor cell motility by ceramide and potential implications for mouse brain development. J Neurochem. 2008 Jul;106(2):718-33 |
Prkcq protein kinase C, theta (Synonyms: A130035A12Rik, PKC-0, Pkcq, PKC theta, PKC-theta, PKCtheta) | |
Results | Reference |
1 | J:87315 Cogram P, Hynes A, Dunlevy LP, Greene ND, Copp AJ, Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol. Hum Mol Genet. 2004 Jan 1;13(1):7-14 |
Prkcsh protein kinase C substrate 80K-H (Synonyms: 80K-H, hepatocystin) | |
Results | Reference |
1 | J:125042 Pierreux CE, Poll AV, Kemp CR, Clotman F, Maestro MA, Cordi S, Ferrer J, Leyns L, Rousseau GG, Lemaigre FP, The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. Gastroenterology. 2006 Feb;130(2):532-41 |
Prkcz protein kinase C, zeta (Synonyms: aPKCzeta, Pkcz, zetaPKC) | |
Results | Reference |
1 | J:327292 Bakhti M, Bastidas-Ponce A, Tritschler S, Czarnecki O, Tarquis-Medina M, Nedvedova E, Jaki J, Willmann SJ, Scheibner K, Cota P, Salinno C, Boldt K, Horn N, Ueffing M, Burtscher I, Theis FJ, Coskun U, Lickert H, Synaptotagmin-13 orchestrates pancreatic endocrine cell egression and islet morphogenesis. Nat Commun. 2022 Aug 4;13(1):4540 |
1 | J:87315 Cogram P, Hynes A, Dunlevy LP, Greene ND, Copp AJ, Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol. Hum Mol Genet. 2004 Jan 1;13(1):7-14 |
1 | J:220324 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C, Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 1;142(5):871-82 |
1 | J:178336 Grosse AS, Pressprich MF, Curley LB, Hamilton KL, Margolis B, Hildebrand JD, Gumucio DL, Cell dynamics in fetal intestinal epithelium: implications for intestinal growth and morphogenesis. Development. 2011 Oct;138(20):4423-32 |
1 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
1 | J:334107 Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J, Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice. Hum Mol Genet. 2022 Oct 10;31(20):3504-3520 |
1* | J:220858 Kim JY, Song JY, Karnam S, Park JY, Lee JJ, Kim S, Cho SH, Common and distinctive localization patterns of Crumbs polarity complex proteins in the mammalian eye. Gene Expr Patterns. 2015 Jan;17(1):31-7 |
1* | J:115984 Kovac J, Oster H, Leitges M, Expression of the atypical protein kinase C (aPKC) isoforms iota/lambda and zeta during mouse embryogenesis. Gene Expr Patterns. 2007 Jan;7(1-2):187-196 |
1* | J:83700 Koyama N, Kashimata M, Sakashita H, Sakagami H, Gresik EW, EGF-stimulated signaling by means of PI3K, PLCgamma1, and PKC isozymes regulates branching morphogenesis of the fetal mouse submandibular gland. Dev Dyn. 2003 Jun;227(2):216-26 |
1 | J:273200 Landin Malt A, Dailey Z, Holbrook-Rasmussen J, Zheng Y, Hogan A, Du Q, Lu X, Par3 is essential for the establishment of planar cell polarity of inner ear hair cells. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4999-5008 |
2 | J:213479 Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, Yoshida N, PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Cereb Cortex. 2013 Aug;23(8):1824-35 |
1 | J:154910 Sugiyama Y, Akimoto K, Robinson ML, Ohno S, Quinlan RA, A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol. 2009 Dec 15;336(2):246-56 |
1 | J:302296 Vong KI, Ma TC, Li B, Leung TCN, Nong W, Ngai SM, Hui JHL, Jiang L, Kwan KM, SOX9-COL9A3-dependent regulation of choroid plexus epithelial polarity governs blood-cerebrospinal fluid barrier integrity. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2009568118 |
Prkd1 protein kinase D1 (Synonyms: Pkcm, PKD1, Prkcm) | |
Results | Reference |
1 | J:87315 Cogram P, Hynes A, Dunlevy LP, Greene ND, Copp AJ, Specific isoforms of protein kinase C are essential for prevention of folate-resistant neural tube defects by inositol. Hum Mol Genet. 2004 Jan 1;13(1):7-14 |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
Prkd3 protein kinase D3 (Synonyms: 4930557O20Rik, 5730497N19Rik, MGC:47171, PKD3, Prkcn) | |
Results | Reference |
1* | J:136668 Ellwanger K, Pfizenmaier K, Lutz S, Hausser A, Expression patterns of protein kinase D 3 during mouse development. BMC Dev Biol. 2008;8:47 |
Prkdc protein kinase, DNA activated, catalytic polypeptide (Synonyms: DNAPDcs, DNA-PK, DNA-PKcs, DOXNPH, dxnph, slip, XRCC7) | |
Results | Reference |
1 | J:255932 Mario Gonzalez-Meljem J, Haston S, Carreno G, Apps JR, Pozzi S, Stache C, Kaushal G, Virasami A, Panousopoulos L, Neda Mousavy-Gharavy S, Guerrero A, Rashid M, Jani N, Goding CR, Jacques TS, Adams DJ, Gil J, Andoniadou CL, Pedro Martinez-Barbera J, Stem cell senescence drives age-attenuated induction of pituitary tumours in mouse models of paediatric craniopharyngioma. Nat Commun. 2017 Nov 28;8(1):1819 |
Prkg2 protein kinase, cGMP-dependent, type II (Synonyms: cGK-II, Prkgr2) | |
Results | Reference |
1* | J:37306 Pfeifer A, Aszodi A, Seidler U, Ruth P, Hofmann F, Fassler R, Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II. Science. 1996 Dec 20;274(5295):2082-6 |
Prkn parkin RBR E3 ubiquitin protein ligase (Synonyms: Park2, Parkin, PRKN) | |
Results | Reference |
1 | J:356661 Esteban-Martinez L, Sierra-Filardi E, McGreal RS, Salazar-Roa M, Marino G, Seco E, Durand S, Enot D, Grana O, Malumbres M, Cvekl A, Cuervo AM, Kroemer G, Boya P, Programmed mitophagy is essential for the glycolytic switch during cell differentiation. EMBO J. 2017 Jun 14;36(12):1688-1706 |
1 | J:333326 Suh J, Kim NK, Shim W, Lee SH, Kim HJ, Moon E, Sesaki H, Jang JH, Kim JE, Lee YS, Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab. 2023 Feb 7;35(2):345-360.e7 |
Prkx protein kinase, X-linked (Synonyms: Pkare) | |
Results | Reference |
1* | J:99976 Li W, Yu ZX, Kotin RM, Profiles of PrKX Expression in Developmental Mouse Embryo and Human Tissues. J Histochem Cytochem. 2005 Aug;53(8):1003-9 |
Prl prolactin (Synonyms: Prl1a1) | |
Results | Reference |
1 | J:236889 Cao D, Ma X, Cai J, Luan J, Liu AJ, Yang R, Cao Y, Zhu X, Zhang H, Chen YX, Shi Y, Shi GX, Zou D, Cao X, Grusby MJ, Xie Z, Zhang WJ, ZBTB20 is required for anterior pituitary development and lactotrope specification. Nat Commun. 2016 Apr 15;7:11121 |
1 | J:235668 Goldsmith S, Lovell-Badge R, Rizzoti K, SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitary. Development. 2016 Jul 1;143(13):2376-88 |
2* | J:39413 Harigaya T, Komori M, Kawakami T, Watanabe H, Abe M, Expression of prolactin gene in mouse placenta during late pregnancy: detection of mRNA and its translation product. Endocr J. 1997 Feb;44(1):155-61 |
1* | J:19457 Japon MA, Rubinstein M, Low MJ, In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development. J Histochem Cytochem. 1994 Aug;42(8):1117-25 |
2 | J:74195 Matsubara M, Harigaya T, Nogami H, Effects of diethylstilbestrol on the cytogenesis of prolactin cells in the pars distalis of the pituitary gland of the mouse. Cell Tissue Res. 2001 Nov;306(2):301-7 |
1* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl2a1 prolactin family 2, subfamily a, member 1 (Synonyms: PLP-M, Prlpm) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl2b1 prolactin family 2, subfamily b, member 1 (Synonyms: 2310047B08Rik, PLP-K, Prlpk) | |
Results | Reference |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl2c2 prolactin family 2, subfamily c, member 2 (Synonyms: MRP-1, Plf, Plf1, PLF-1) | |
Results | Reference |
1 | J:186550 Jackman SM, Kong X, Fant ME, Plac1 (placenta-specific 1) is essential for normal placental and embryonic development. Mol Reprod Dev. 2012 Aug;79(8):564-72 |
1 | J:123073 Kruger I, Vollmer M, Simmons DG, Elsasser HP, Philipsen S, Suske G, Sp1/Sp3 compound heterozygous mice are not viable: Impaired erythropoiesis and severe placental defects. Dev Dyn. 2007 Aug;236(8):2235-44 |
1 | J:165668 Nadra K, Quignodon L, Sardella C, Joye E, Mucciolo A, Chrast R, Desvergne B, PPARgamma in placental angiogenesis. Endocrinology. 2010 Oct;151(10):4969-81 |
1 | J:122534 Simmons DG, Fortier AL, Cross JC, Diverse subtypes and developmental origins of trophoblast giant cells in the mouse placenta. Dev Biol. 2007 Apr 15;304(2):567-78 |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
1* | J:51098 Yotsumoto S, Shimada T, Cui CY, Nakashima H, Fujiwara H, Ko MS, Expression of adrenomedullin, a hypotensive peptide, in the trophoblast giant cells at the embryo implantation site in mouse. Dev Biol. 1998 Nov 15;203(2):264-75 |
Prl2c3 prolactin family 2, subfamily c, member 3 (Synonyms: MRP-2, MRP-3, mrp/plf3, Mrpplf3, Plf2, PLF-2, PLF-3, Prl2c4) | |
Results | Reference |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl2c5 prolactin family 2, subfamily c, member 5 (Synonyms: MRP-4, Mrpplf4, PLF-4) | |
Results | Reference |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl3a1 prolactin family 3, subfamily a, member 1 (Synonyms: 1600016E11Rik, PLP-H, Plpi, PLP-I, Prlpi) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
2 | J:180846 Saito K, Ogawa A, Toyofuku K, Hosoi Y, Soma M, Iha M, Kasuga K, Kojima I, Kobayashi M, Relationships between homeoprotein EGAM1C and the expression of the placental prolactin gene family in mouse placentae and trophoblast stem cells. Reproduction. 2011 Feb;141(2):259-68 |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl3b1 prolactin family 3, subfamily b, member 1 (Synonyms: Csh2, mplII, mPL-II, PL, Pl-2, Pl2, prolactin-like) | |
Results | Reference |
1* | J:36835 Monkley SJ, Delaney SJ, Pennisi DJ, Christiansen JH, Wainwright BJ, Targeted disruption of the Wnt2 gene results in placentation defects. Development. 1996 Nov;122(11):3343-53 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
2 | J:180846 Saito K, Ogawa A, Toyofuku K, Hosoi Y, Soma M, Iha M, Kasuga K, Kojima I, Kobayashi M, Relationships between homeoprotein EGAM1C and the expression of the placental prolactin gene family in mouse placentae and trophoblast stem cells. Reproduction. 2011 Feb;141(2):259-68 |
1 | J:138768 Screen M, Dean W, Cross JC, Hemberger M, Cathepsin proteases have distinct roles in trophoblast function and vascular remodelling. Development. 2008 Oct;135(19):3311-20 |
1 | J:100602 Simmons DG, Cross JC, Determinants of trophoblast lineage and cell subtype specification in the mouse placenta. Dev Biol. 2005 Aug 1;284(1):12-24 |
1 | J:122534 Simmons DG, Fortier AL, Cross JC, Diverse subtypes and developmental origins of trophoblast giant cells in the mouse placenta. Dev Biol. 2007 Apr 15;304(2):567-78 |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
Prl3c1 prolactin family 3, subfamily c, member 1 (Synonyms: PLP I, PLP-J, Prlpj) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl3d1 prolactin family 3, subfamily d, member 1 (Synonyms: Csh1, mPL-I, Pl-1, Pl1, placental lactogen 1, PL-Ia, prolactin-like 2) | |
Results | Reference |
1 | J:180242 Dupressoir A, Vernochet C, Harper F, Guegan J, Dessen P, Pierron G, Heidmann T, A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1164-73 |
1 | J:107381 Nadra K, Anghel SI, Joye E, Tan NS, Basu-Modak S, Trono D, Wahli W, Desvergne B, Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta. Mol Cell Biol. 2006 Apr;26(8):3266-81 |
1 | J:119564 Shiota C, Woo JT, Lindner J, Shelton KD, Magnuson MA, Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability. Dev Cell. 2006 Oct;11(4):583-9 |
1 | J:122534 Simmons DG, Fortier AL, Cross JC, Diverse subtypes and developmental origins of trophoblast giant cells in the mouse placenta. Dev Biol. 2007 Apr 15;304(2):567-78 |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl3d2 prolactin family 3, subfamily d, member 2 (Synonyms: Plib, PL-Ib) | |
Results | Reference |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl3d3 prolactin family 3, subfamily d, member 3 (Synonyms: Plig, PL-Ig) | |
Results | Reference |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl4a1 prolactin family 4, subfamily a, member 1 (Synonyms: PLP-A, Prlpa) | |
Results | Reference |
2 | J:44831 Muller H, Ishimura R, Orwig KE, Liu B, Soares MJ, Homologues for prolactin-like proteins A and B are present in the mouse. Biol Reprod. 1998 Jan;58(1):45-51 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl5a1 prolactin family 5, subfamily a, member 1 (Synonyms: 1600013P04Rik, D13Wsu14e, PLP-L, Prlpl) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
2 | J:180846 Saito K, Ogawa A, Toyofuku K, Hosoi Y, Soma M, Iha M, Kasuga K, Kojima I, Kobayashi M, Relationships between homeoprotein EGAM1C and the expression of the placental prolactin gene family in mouse placentae and trophoblast stem cells. Reproduction. 2011 Feb;141(2):259-68 |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl6a1 prolactin family 6, subfamily a, member 1 (Synonyms: PLP-B, Prlpb) | |
Results | Reference |
2 | J:44831 Muller H, Ishimura R, Orwig KE, Liu B, Soares MJ, Homologues for prolactin-like proteins A and B are present in the mouse. Biol Reprod. 1998 Jan;58(1):45-51 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
3* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl7a1 prolactin family 7, subfamily a, member 1 (Synonyms: PLP-E, PLP-G, Prlpe, Prlpg) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
3* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl7a2 prolactin family 7, subfamily a, member 2 (Synonyms: PLP-F, Prlpf) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl7b1 prolactin family 7, subfamily b, member 1 (Synonyms: 1600014J19Rik, PLP-N, Prlpn) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl7c1 prolactin family 7, subfamily c, member 1 (Synonyms: 1600017N11Rik, PLP-O, Prlpo) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl7d1 prolactin family 7, subfamily d, member 1 (Synonyms: Plfr, PLF-RP, PRP) | |
Results | Reference |
1 | J:129983 Colosi P, Swiergiel JJ, Wilder EL, Oviedo A, Linzer DI, Characterization of proliferin-related protein. Mol Endocrinol. 1988 Jun;2(6):579-86 |
1 | J:165668 Nadra K, Quignodon L, Sardella C, Joye E, Mucciolo A, Chrast R, Desvergne B, PPARgamma in placental angiogenesis. Endocrinology. 2010 Oct;151(10):4969-81 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl8a1 prolactin family 8, subfamily a, member 1 (Synonyms: 1600017L04Rik, 3830403L08Rik, Plpcd, PLP-Cd, Prlpc4) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
3* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl8a2 prolactin family 8, subfamily a, member 2 (Synonyms: DPRP, Dtprp, D/tPRP, mdPRP) | |
Results | Reference |
2 | J:42315 Orwig KE, Ishimura R, Muller H, Liu B, Soares MJ, Identification and characterization of a mouse homolog for decidual/trophoblast prolactin-related protein. Endocrinology. 1997 Dec;138(12):5511-7 |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl8a6 prolactin family 8, subfamily a, member 6 (Synonyms: PLP-Ca, PLP-calpha, Prlpc, Prlpc1) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
3* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prl8a8 prolactin family 8, subfamily a, member 81 (Synonyms: 1600032B14Rik, PLP-Cgamma, Prlpc3) | |
Results | Reference |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
1 | J:186550 Jackman SM, Kong X, Fant ME, Plac1 (placenta-specific 1) is essential for normal placental and embryonic development. Mol Reprod Dev. 2012 Aug;79(8):564-72 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
3* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
Prl8a9 prolactin family8, subfamily a, member 9 (Synonyms: 1600019F10Rik, PLP-Cbeta, Prlpc2) | |
Results | Reference |
1* | J:76726 Hwang IT, Lee YH, Moon BC, Ahn KY, Lee SW, Chun JY, Identification and characterization of a new member of the placental prolactin-like protein-C (PLP-C) subfamily, PLP-Cbeta. Endocrinology. 2000;141(9):3343-3352 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
2* | J:139954 Simmons DG, Rawn S, Davies A, Hughes M, Cross JC, Spatial and temporal expression of the 23 murine Prolactin/Placental Lactogen-related genes is not associated with their position in the locus. BMC Genomics. 2008;9:352 |
Prlr prolactin receptor (Synonyms: Pr-1, Prlr-rs1) | |
Results | Reference |
1* | J:33825 Brown-Borg HM, Zhang FP, Huhtaniemi I, Bartke A, Developmental aspects of prolactin receptor gene expression in fetal and neonatal mice. Eur J Endocrinol. 1996 Jun;134(6):751-7 |
Prmt2 protein arginine N-methyltransferase 2 (Synonyms: Hrmt1l1) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Prmt5 protein arginine N-methyltransferase 5 (Synonyms: Jak-binding protein 1, Jbp1, Skb1) | |
Results | Reference |
2 | J:264403 Li Q, Jiao J, Li H, Wan H, Zheng C, Cai J, Bao S, Histone arginine methylation by Prmt5 is required for lung branching morphogenesis through repression of BMP signaling. J Cell Sci. 2018 Jul 25;131(14):jcs217406 |
Prmt7 protein arginine N-methyltransferase 7 (Synonyms: 4933402B05Rik, MGC:7929) | |
Results | Reference |
1 | J:305337 Chen M, Wang Y, Lin L, Dong F, Wu H, Bao S, Gao F, PRMT7 is involved in regulation of germ cell proliferation during embryonic stage. Biochem Biophys Res Commun. 2020 Dec 17;533(4):938-944 |
Prmt8 protein arginine N-methyltransferase 8 (Synonyms: Hrmt1l3, Hrmt1l4) | |
Results | Reference |
1* | J:122500 Taneda T, Miyata S, Kousaka A, Inoue K, Koyama Y, Mori Y, Tohyama M, Specific regional distribution of protein arginine methyltransferase 8 (PRMT8) in the mouse brain. Brain Res. 2007 Jun 25;1155:1-9 |
Prnp prion protein (Synonyms: CD230, Prn-i, Prn-p, PrP, PrPC, PrPSc, Sinc) | |
Results | Reference |
1* | J:174473 Benvegnu S, Poggiolini I, Legname G, Neurodevelopmental expression and localization of the cellular prion protein in the central nervous system of the mouse. J Comp Neurol. 2010 Jun 1;518(11):1879-91 |
1 | J:187211 Bribian A, Fontana X, Llorens F, Gavin R, Reina M, Garcia-Verdugo JM, Torres JM, de Castro F, del Rio JA, Role of the cellular prion protein in oligodendrocyte precursor cell proliferation and differentiation in the developing and adult mouse CNS. PLoS One. 2012;7(4):e33872 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:167050 Khan QE, Press CM, Sehic A, Landin MA, Risnes S, Osmundsen H, Expression of prion gene and presence of prion protein during development of mouse molar tooth germ. Eur J Oral Sci. 2010 Dec;118(6):559-65 |
1 | J:188148 Landin MA, Shabestari M, Babaie E, Reseland JE, Osmundsen H, Gene Expression Profiling during Murine Tooth Development. Front Genet. 2012;3:139 |
1* | J:1109 Manson J, West JD, Thomson V, McBride P, Kaufman MH, Hope J, The prion protein gene: a role in mouse embryogenesis?. Development. 1992 May;115(1):117-22 |
1* | J:172286 Miranda A, Pericuesta E, Ramirez MA, Gutierrez-Adan A, Prion protein expression regulates embryonic stem cell pluripotency and differentiation. PLoS One. 2011;6(4):e18422 |
Procr protein C receptor, endothelial (Synonyms: Ccca, EPCR) | |
Results | Reference |
1* | J:80863 Crawley JT, Gu JM, Ferrell G, Esmon CT, Distribution of endothelial cell protein C/activated protein C receptor (EPCR) during mouse embryo development. Thromb Haemost. 2002 Aug;88(2):259-66 |
Prokr1 prokineticin receptor 1 (Synonyms: EG-VEGFR1, Gpr73, Pkr1) | |
Results | Reference |
1 | J:239479 Arora H, Boulberdaa M, Qureshi R, Bitirim V, Messadeq N, Dolle P, Nebigil CG, Prokineticin receptor 1 is required for mesenchymal-epithelial transition in kidney development. FASEB J. 2016 Aug;30(8):2733-40 |
Prokr2 prokineticin receptor 2 (Synonyms: B830005M06Rik, EG-VEGRF2, Gpcr73l1, Gpr73l1, PKR2) | |
Results | Reference |
1 | J:188332 Delogu A, Sellers K, Zagoraiou L, Bocianowska-Zbrog A, Mandal S, Guimera J, Rubenstein JL, Sugden D, Jessell T, Lumsden A, Subcortical visual shell nuclei targeted by ipRGCs develop from a Sox14+-GABAergic progenitor and require Sox14 to regulate daily activity rhythms. Neuron. 2012 Aug 23;75(4):648-62 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:264268 Li J, Wang C, Zhang Z, Wen Y, An L, Liang Q, Xu Z, Wei S, Li W, Guo T, Liu G, Tao G, You Y, Du H, Fu Z, He M, Chen B, Campbell K, Alvarez-Buylla A, Rubenstein JL, Yang Z, Transcription Factors Sp8 and Sp9 Coordinately Regulate Olfactory Bulb Interneuron Development. Cereb Cortex. 2018 Sep 1;28(9):3278-3294 |
1* | J:107587 Matsumoto S, Yamazaki C, Masumoto KH, Nagano M, Naito M, Soga T, Hiyama H, Matsumoto M, Takasaki J, Kamohara M, Matsuo A, Ishii H, Kobori M, Katoh M, Matsushime H, Furuichi K, Shigeyoshi Y, Abnormal development of the olfactory bulb and reproductive system in mice lacking prokineticin receptor PKR2. Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):4140-5 |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
Prol1 proline rich, lacrimal 1 (Synonyms: Muc10) | |
Results | Reference |
1* | J:49213 Jaskoll T, Chen H, Denny PC, Denny PA, Melnick M, Mouse submandibular gland mucin: embryo-specific mRNA and protein species. Mech Dev. 1998 Jun;74(1-2):179-83 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
Prom1 prominin 1 (Synonyms: 4932416E19Rik, AC133, CD133, Prom, Prom-1) | |
Results | Reference |
1 | J:166772 DeRouen MC, Zhen H, Tan SH, Williams S, Marinkovich MP, Oro AE, Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation. BMC Dev Biol. 2010;10:112 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:193958 Huh SH, Narhi K, Lindfors PH, Haara O, Yang L, Ornitz DM, Mikkola ML, Fgf20 governs formation of primary and secondary dermal condensations in developing hair follicles. Genes Dev. 2013 Feb 15;27(4):450-8 |
1 | J:121090 Ito Y, Hamazaki TS, Ohnuma K, Tamaki K, Asashima M, Okochi H, Isolation of murine hair-inducing cells using the cell surface marker prominin-1/CD133. J Invest Dermatol. 2007 May;127(5):1052-60 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
2 | J:227725 Kaushal GS, Rognoni E, Lichtenberger BM, Driskell RR, Kretzschmar K, Hoste E, Watt FM, Fate of Prominin-1 Expressing Dermal Papilla Cells during Homeostasis, Wound Healing and Wnt Activation. J Invest Dermatol. 2015 Dec;135(12):2926-34 |
1* | J:202344 Lesko MH, Driskell RR, Kretzschmar K, Goldie SJ, Watt FM, Sox2 modulates the function of two distinct cell lineages in mouse skin. Dev Biol. 2013 Oct 1;382(1):15-26 |
1 | J:124218 Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan YN, Rakic P, Sestan N, Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci. 2007 Jul;10(7):819-27 |
Prop1 paired like homeodomain factor 1 (Synonyms: Prop-1, prophet of Pit-1, prophet of Pit1) | |
Results | Reference |
1* | J:73085 Dasen JS, Barbera JP, Herman TS, Connell SO, Olson L, Ju B, Tollkuhn J, Baek SH, Rose DW, Rosenfeld MG, Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 1;15(23):3193-207 |
Prox1 prospero homeobox 1 (Synonyms: A230003G05Rik) | |
Results | Reference |
1 | J:181188 Aoki H, Hara A, Era T, Kunisada T, Yamada Y, Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development. 2012 Feb;139(4):667-77 |
1 | J:317549 Aryal S, Viet J, Weatherbee BAT, Siddam AD, Hernandez FG, Gautier-Courteille C, Paillard L, Lachke SA, The cataract-linked RNA-binding protein Celf1 post-transcriptionally controls the spatiotemporal expression of the key homeodomain transcription factors Pax6 and Prox1 in lens development. Hum Genet. 2020 Dec;139(12):1541-1554 |
1* | J:142365 Barry G, Piper M, Lindwall C, Moldrich R, Mason S, Little E, Sarkar A, Tole S, Gronostajski RM, Richards LJ, Specific glial populations regulate hippocampal morphogenesis. J Neurosci. 2008 Nov 19;28(47):12328-40 |
1* | J:181601 Bassett EA, Korol A, Deschamps PA, Buettner R, Wallace VA, Williams T, West-Mays JA, Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29 |
1 | J:152968 Bazigou E, Xie S, Chen C, Weston A, Miura N, Sorokin L, Adams R, Muro AF, Sheppard D, Makinen T, Integrin-alpha9 is required for fibronectin matrix assembly during lymphatic valve morphogenesis. Dev Cell. 2009 Aug;17(2):175-86 |
1 | J:229394 Bernier-Latmani J, Cisarovsky C, Demir CS, Bruand M, Jaquet M, Davanture S, Ragusa S, Siegert S, Dormond O, Benedito R, Radtke F, Luther SA, Petrova TV, DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport. J Clin Invest. 2015 Dec;125(12):4572-86 |
1 | J:316182 Blume M, Inoguchi F, Sugiyama T, Owada Y, Osumi N, Aimi Y, Taki K, Katsuyama Y, Dab1 contributes differently to the morphogenesis of the hippocampal subdivisions. Dev Growth Differ. 2017 Oct;59(8):657-673 |
2 | J:269938 Bovay E, Sabine A, Prat-Luri B, Kim S, Son K, Willrodt AH, Olsson C, Halin C, Kiefer F, Betsholtz C, Jeon NL, Luther SA, Petrova TV, Multiple roles of lymphatic vessels in peripheral lymph node development. J Exp Med. 2018 Nov 5;215(11):2760-2777 |
1 | J:199451 Brunne B, Franco S, Bouche E, Herz J, Howell BW, Pahle J, Muller U, May P, Frotscher M, Bock HH, Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by reelin signaling mutant mice. Glia. 2013 Aug;61(8):1347-63 |
1 | J:326462 Byrne AB, Brouillard P, Sutton DL, Kazenwadel J, Montazaribarforoushi S, Secker GA, Oszmiana A, Babic M, Betterman KL, Brautigan PJ, White M, Piltz SG, Thomas PQ, Hahn CN, Rath M, Felbor U, Korenke GC, Smith CL, Wood KH, Sheppard SE, Adams DM, Kariminejad A, Helaers R, Boon LM, Revencu N, Moore L, Barnett C, Haan E, Arts P, Vikkula M, Scott HS, Harvey NL, Pathogenic variants in MDFIC cause recessive central conducting lymphatic anomaly with lymphedema. Sci Transl Med. 2022 Mar 2;14(634):eabm4869 |
1 | J:302542 Cahill TJ, Sun X, Ravaud C, Villa Del Campo C, Klaourakis K, Lupu IE, Lord AM, Browne C, Jacobsen SEW, Greaves DR, Jackson DG, Cowley SA, James W, Choudhury RP, Vieira JM, Riley PR, Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart. Development. 2021 Feb 3;148(3):dev194563 |
1 | J:233304 Cha B, Geng X, Mahamud MR, Fu J, Mukherjee A, Kim Y, Jho EH, Kim TH, Kahn ML, Xia L, Dixon JB, Chen H, Srinivasan RS, Mechanotransduction activates canonical Wnt/beta-catenin signaling to promote lymphatic vascular patterning and the development of lymphatic and lymphovenous valves. Genes Dev. 2016 Jun 15;30(12):1454-69 |
2 | J:269779 Cha B, Geng X, Mahamud MR, Zhang JY, Chen L, Kim W, Jho EH, Kim Y, Choi D, Dixon JB, Chen H, Hong YK, Olson L, Kim TH, Merrill BJ, Davis MJ, Srinivasan RS, Complementary Wnt Sources Regulate Lymphatic Vascular Development via PROX1-Dependent Wnt/beta-Catenin Signaling. Cell Rep. 2018 Oct 16;25(3):571-584.e5 |
1 | J:301556 Cha B, Ho YC, Geng X, Mahamud MR, Chen L, Kim Y, Choi D, Kim TH, Randolph GJ, Cao X, Chen H, Srinivasan RS, YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling. Development. 2020 Dec 13;147(23):dev195453 |
1 | J:227188 Choe Y, Huynh T, Pleasure SJ, Epithelial cells supply Sonic Hedgehog to the perinatal dentate gyrus via transport by platelets. Elife. 2015;4 |
1 | J:196652 Choe Y, Kozlova A, Graf D, Pleasure SJ, Bone morphogenic protein signaling is a major determinant of dentate development. J Neurosci. 2013 Apr 17;33(16):6766-75 |
1 | J:226607 Clegg JM, Li Z, Molinek M, Caballero IM, Manuel MN, Price DJ, Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons. Neural Dev. 2015;10(1):26 |
1 | J:142229 Dabdoub A, Puligilla C, Jones JM, Fritzsch B, Cheah KS, Pevny LH, Kelley MW, Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18396-401 |
1 | J:93150 Dagenais SL, Hartsough RL, Erickson RP, Witte MH, Butler MG, Glover TW, Foxc2 is expressed in developing lymphatic vessels and other tissues associated with lymphedema-distichiasis syndrome. Gene Expr Patterns. 2004 Oct;4(6):611-9 |
1 | J:206101 Danussi C, Del Bel Belluz L, Pivetta E, Modica TM, Muro A, Wassermann B, Doliana R, Sabatelli P, Colombatti A, Spessotto P, EMILIN1/alpha9beta1 integrin interaction is crucial in lymphatic valve formation and maintenance. Mol Cell Biol. 2013 Nov;33(22):4381-94 |
1 | J:173617 de Melo J, Peng GH, Chen S, Blackshaw S, The Spalt family transcription factor Sall3 regulates the development of cone photoreceptors and retinal horizontal interneurons. Development. 2011 Jun;138(11):2325-36 |
1 | J:359863 Do LNH, Delgado E, Lim CG, Bkhache M, Peluzzo AM, Hua Y, Oza M, Mohsin S, Chen H, Autieri MV, Kim S, Liu X, A neuro-lymphatic communication guides lymphatic development by CXCL12 and CXCR4 signaling. Development. 2024 Nov 15;151(22) |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
1* | J:145843 Duncan MK, Cui W, Oh DJ, Tomarev SI, Prox1 is differentially localized during lens development. Mech Dev. 2002 Mar;112(1-2):195-8 |
1 | J:59284 Galceran J, Miyashita-Lin EM, Devaney E, Rubenstein JL, Grosschedl R, Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1. Development. 2000 Feb;127(3):469-82 |
1 | J:134976 Galichet C, Guillemot F, Parras CM, Neurogenin 2 has an essential role in development of the dentate gyrus. Development. 2008 Jun;135(11):2031-41 |
1 | J:228882 Geng X, Cha B, Mahamud MR, Lim KC, Silasi-Mansat R, Uddin MK, Miura N, Xia L, Simon AM, Engel JD, Chen H, Lupu F, Srinivasan RS, Multiple mouse models of primary lymphedema exhibit distinct defects in lymphovenous valve development. Dev Biol. 2016 Jan 1;409(1):218-33 |
1 | J:308918 Geng X, Yanagida K, Akwii RG, Choi D, Chen L, Ho Y, Cha B, Mahamud MR, Berman de Ruiz K, Ichise H, Chen H, Wythe JD, Mikelis CM, Hla T, Srinivasan RS, S1PR1 regulates the quiescence of lymphatic vessels by inhibiting laminar shear stress-dependent VEGF-C signaling. JCI Insight. 2020 Jul 23;5(14) |
1* | J:137168 Gordon EJ, Gale NW, Harvey NL, Expression of the hyaluronan receptor LYVE-1 is not restricted to the lymphatic vasculature; LYVE-1 is also expressed on embryonic blood vessels. Dev Dyn. 2008 Jul;237(7):1901-9 |
2 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1 | J:102652 Harvey NL, Srinivasan RS, Dillard ME, Johnson NC, Witte MH, Boyd K, Sleeman MW, Oliver G, Lymphatic vascular defects promoted by Prox1 haploinsufficiency cause adult-onset obesity. Nat Genet. 2005 Oct;37(10):1072-81 |
1 | J:308528 Hernandez Vasquez MN, Ulvmar MH, Gonzalez-Loyola A, Kritikos I, Sun Y, He L, Halin C, Petrova TV, Makinen T, Transcription factor FOXP2 is a flow-induced regulator of collecting lymphatic vessels. EMBO J. 2021 Jun 15;40(12):e107192 |
1 | J:196059 Hodge RD, Garcia AJ 3rd, Elsen GE, Nelson BR, Mussar KE, Reiner SL, Ramirez JM, Hevner RF, Tbr2 expression in Cajal-Retzius cells and intermediate neuronal progenitors is required for morphogenesis of the dentate gyrus. J Neurosci. 2013 Feb 27;33(9):4165-80 |
1 | J:160260 Hufnagel RB, Le TT, Riesenberg AL, Brown NL, Neurog2 controls the leading edge of neurogenesis in the mammalian retina. Dev Biol. 2010 Apr 15;340(2):490-503 |
1 | J:315409 Huyghe A, Van den Ackerveken P, Sacheli R, Prevot PP, Thelen N, Renauld J, Thiry M, Delacroix L, Nguyen L, Malgrange B, MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5. Cell Rep. 2015 Oct 6;13(1):31-42 |
1 | J:341378 Iyer D, Mastrogiacomo DM, Li K, Banerjee R, Yang Y, Scallan JP, eNOS Regulates Lymphatic Valve Specification by Controlling beta-Catenin Signaling During Embryogenesis in Mice. Arterioscler Thromb Vasc Biol. 2023 Sep 28; |
1* | J:293098 Jafree DJ, Moulding D, Kolatsi-Joannou M, Perretta Tejedor N, Price KL, Milmoe NJ, Walsh CL, Correra RM, Winyard PJ, Harris PC, Ruhrberg C, Walker-Samuel S, Riley PR, Woolf AS, Scambler PJ, Long DA, Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease. Elife. 2019 Dec 6;8:e48183 |
1 | J:334107 Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J, Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice. Hum Mol Genet. 2022 Oct 10;31(20):3504-3520 |
1* | J:139639 Juszynski M, Ciszek B, Stachurska E, Jablonska A, Ratajska A, Development of lymphatic vessels in mouse embryonic and early postnatal hearts. Dev Dyn. 2008 Sep 24;237(10):2973-2986 |
1 | J:170546 Kaltezioti V, Kouroupi G, Oikonomaki M, Mantouvalou E, Stergiopoulos A, Charonis A, Rohrer H, Matsas R, Politis PK, Prox1 regulates the notch1-mediated inhibition of neurogenesis. PLoS Biol. 2010;8(12):e1000565 |
1 | J:197212 Kim HJ, Woo HM, Ryu J, Bok J, Kim JW, Choi SB, Park MH, Park HY, Koo SK, Conditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development. PLoS One. 2013;8(2):e55609 |
1 | J:222438 Klimova L, Antosova B, Kuzelova A, Strnad H, Kozmik Z, Onecut1 and Onecut2 transcription factors operate downstream of Pax6 to regulate horizontal cell development. Dev Biol. 2015 Jun 1;402(1):48-60 |
1 | J:222246 Klotz L, Norman S, Vieira JM, Masters M, Rohling M, Dube KN, Bollini S, Matsuzaki F, Carr CA, Riley PR, Cardiac lymphatics are heterogeneous in origin and respond to injury. Nature. 2015 Jun 4;522(7554):62-7 |
1 | J:166777 Lavado A, Lagutin OV, Chow LM, Baker SJ, Oliver G, Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. PLoS Biol. 2010;8(8) |
2* | J:117269 Lavado A, Oliver G, Prox1 expression patterns in the developing and adult murine brain. Dev Dyn. 2007 Feb;236(2):518-24 |
1 | J:178118 Li Q, Bian S, Hong J, Kawase-Koga Y, Zhu E, Zheng Y, Yang L, Sun T, Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development. PLoS One. 2011;6(10):e26000 |
2 | J:223043 Liebl J, Zhang S, Moser M, Agalarov Y, Demir CS, Hager B, Bibb JA, Adams RH, Kiefer F, Miura N, Petrova TV, Vollmar AM, Zahler S, Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2. Nat Commun. 2015;6:7274 |
1 | J:332090 Lioux G, Liu X, Temino S, Oxendine M, Ayala E, Ortega S, Kelly RG, Oliver G, Torres M, A Second Heart Field-Derived Vasculogenic Niche Contributes to Cardiac Lymphatics. Dev Cell. 2020 Feb 10;52(3):350-363.e6 |
1* | J:310860 Liu S, Wang Y, Lu Y, Li W, Liu W, Ma J, Sun F, Li M, Chen ZY, Su K, Li W, The Key Transcription Factor Expression in the Developing Vestibular and Auditory Sensory Organs: A Comprehensive Comparison of Spatial and Temporal Patterns. Neural Plast. 2018;2018:7513258 |
1 | J:244674 Liu X, Pasula S, Song H, Tessneer KL, Dong Y, Hahn S, Yago T, Brophy ML, Chang B, Cai X, Wu H, McManus J, Ichise H, Georgescu C, Wren JD, Griffin C, Xia L, Srinivasan RS, Chen H, Temporal and spatial regulation of epsin abundance and VEGFR3 signaling are required for lymphatic valve formation and function. Sci Signal. 2014 Oct 14;7(347):ra97 |
1* | J:81783 Lu M, Grove EA, Miller RJ, Abnormal development of the hippocampal dentate gyrus in mice lacking the CXCR4 chemokine receptor. Proc Natl Acad Sci U S A. 2002 May 14;99(10):7090-5 |
1 | J:276746 Lutze G, Haarmann A, Demanou Toukam JA, Buttler K, Wilting J, Becker J, Non-canonical WNT-signaling controls differentiation of lymphatics and extension lymphangiogenesis via RAC and JNK signaling. Sci Rep. 2019 Mar 18;9(1):4739 |
1 | J:316476 Ma W, Gil HJ, Liu X, Diebold LP, Morgan MA, Oxendine-Burns MJ, Gao P, Chandel NS, Oliver G, Mitochondrial respiration controls the Prox1-Vegfr3 feedback loop during lymphatic endothelial cell fate specification and maintenance. Sci Adv. 2021 Apr;7(18) |
2 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
1 | J:284120 Mahamud MR, Geng X, Ho YC, Cha B, Kim Y, Ma J, Chen L, Myers G, Camper S, Mustacich D, Witte M, Choi D, Hong YK, Chen H, Varshney G, Engel JD, Wang S, Kim TH, Lim KC, Srinivasan RS, GATA2 controls lymphatic endothelial cell junctional integrity and lymphovenous valve morphogenesis through miR-126. Development. 2019 Nov 5;146(21):dev184218 |
1 | J:207861 Manthey AL, Lachke SA, FitzGerald PG, Mason RW, Scheiblin DA, McDonald JH, Duncan MK, Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development. Mech Dev. 2014 Feb;131:86-110 |
1* | J:278916 Maruyama K, Miyagawa-Tomita S, Mizukami K, Matsuzaki F, Kurihara H, Isl1-expressing non-venous cell lineage contributes to cardiac lymphatic vessel development. Dev Biol. 2019 Aug 15;452(2):134-143 |
2 | J:306872 Maruyama K, Naemura K, Arima Y, Uchijima Y, Nagao H, Yoshihara K, Singh MK, Uemura A, Matsuzaki F, Yoshida Y, Kurihara Y, Miyagawa-Tomita S, Kurihara H, Semaphorin3E-PlexinD1 signaling in coronary artery and lymphatic vessel development with clinical implications in myocardial recovery. iScience. 2021 Apr 23;24(4):102305 |
1 | J:226398 Miyoshi G, Young A, Petros T, Karayannis T, McKenzie Chang M, Lavado A, Iwano T, Nakajima M, Taniguchi H, Huang ZJ, Heintz N, Oliver G, Matsuzaki F, Machold RP, Fishell G, Prox1 Regulates the Subtype-Specific Development of Caudal Ganglionic Eminence-Derived GABAergic Cortical Interneurons. J Neurosci. 2015 Sep 16;35(37):12869-89 |
1 | J:262023 Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K, Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling. Circ Res. 2017 Apr 14;120(8):1276-1288 |
1 | J:231667 Munger SJ, Geng X, Srinivasan RS, Witte MH, Paul DL, Simon AM, Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice. Dev Biol. 2016 Apr 15;412(2):173-90 |
1 | J:213874 Murtomaki A, Uh MK, Kitajewski C, Zhao J, Nagasaki T, Shawber CJ, Kitajewski J, Notch signaling functions in lymphatic valve formation. Development. 2014 Jun;141(12):2446-51 |
1 | J:98698 Muzio L, Mallamaci A, Foxg1 confines Cajal-Retzius neuronogenesis and hippocampal morphogenesis to the dorsomedial pallium. J Neurosci. 2005 Apr 27;25(17):4435-41 |
2* | J:137801 Nakayama A, Miura H, Shindo Y, Kusakabe Y, Tomonari H, Harada S, Expression of the basal cell markers of taste buds in the anterior tongue and soft palate of the mouse embryo. J Comp Neurol. 2008 Jul 10;509(2):211-24 |
1 | J:272073 Nicola Z, Fabel K, Kempermann G, Development of the adult neurogenic niche in the hippocampus of mice. Front Neuroanat. 2015;9:53 |
1 | J:275825 Norman TA Jr, Gower AC, Chen F, Fine A, Transcriptional landscape of pulmonary lymphatic endothelial cells during fetal gestation. PLoS One. 2019;14(5):e0216795 |
1 | J:149138 Norrmen C, Ivanov KI, Cheng J, Zangger N, Delorenzi M, Jaquet M, Miura N, Puolakkainen P, Horsley V, Hu J, Augustin HG, Yla-Herttuala S, Alitalo K, Petrova TV, FOXC2 controls formation and maturation of lymphatic collecting vessels through cooperation with NFATc1. J Cell Biol. 2009 May 4;185(3):439-57 |
1 | J:354217 Ohyama K, Shinohara HM, Takayama N, Ogawa R, Omura S, Hayashida M, Takahashi T, Differentiation stage-specific expression of transcriptional regulators for epithelial mesenchymal transition in dentate granule progenitors. Front Neurosci. 2024;18:1425849 |
1* | J:16397 Oliver G, Sosa-Pineda B, Geisendorf S, Spana EP, Doe CQ, Gruss P, Prox 1, a prospero-related homeobox gene expressed during mouse development. Mech Dev. 1993 Nov;44(1):3-16 |
1 | J:331057 Parichha A, Datta D, Suresh V, Chatterjee M, Holtzman MJ, Tole S, Dentate gyrus morphogenesis is regulated by beta-catenin function in hem-derived fimbrial glia. Development. 2022 Nov 1;149(21):dev200953 |
1 | J:320719 Parichha A, Suresh V, Chatterjee M, Kshirsagar A, Ben-Reuven L, Olender T, Taketo MM, Radosevic V, Bobic-Rasonja M, Trnski S, Holtzman MJ, Jovanov-Milosevic N, Reiner O, Tole S, Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate. Nat Commun. 2022 Feb 2;13(1):633 |
1 | J:241853 Parisot J, Flore G, Bertacchi M, Studer M, COUP-TFI mitotically regulates production and migration of dentate granule cells and modulates hippocampal Cxcr4 expression. Development. 2017 Jun 01;144(11):2045-2058 |
1 | J:246400 Paul L, Walker EM, Drosos Y, Cyphert HA, Neale G, Stein R, South J, Grosveld G, Herrera PL, Sosa-Pineda B, Lack of Prox1 Downregulation Disrupts the Expansion and Maturation of Postnatal Murine beta-Cells. Diabetes. 2016 Mar;65(3):687-98 |
1 | J:308707 Paulson D, Harms R, Ward C, Latterell M, Pazour GJ, Fink DM, Loss of Primary Cilia Protein IFT20 Dysregulates Lymphatic Vessel Patterning in Development and Inflammation. Front Cell Dev Biol. 2021;9:672625 |
1 | J:264119 Pichol-Thievend C, Betterman KL, Liu X, Ma W, Skoczylas R, Lesieur E, Bos FL, Schulte D, Schulte-Merker S, Hogan BM, Oliver G, Harvey NL, Francois M, A blood capillary plexus-derived population of progenitor cells contributes to genesis of the dermal lymphatic vasculature during embryonic development. Development. 2018 May 17;145(10):dev160184 |
2 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:130904 Poche RA, Kwan KM, Raven MA, Furuta Y, Reese BE, Behringer RR, Lim1 is essential for the correct laminar positioning of retinal horizontal cells. J Neurosci. 2007 Dec 19;27(51):14099-107 |
1 | J:269234 Pujol F, Hodgson T, Martinez-Corral I, Prats AC, Devenport D, Takeichi M, Genot E, Makinen T, Francis-West P, Garmy-Susini B, Tatin F, Dachsous1-Fat4 Signaling Controls Endothelial Cell Polarization During Lymphatic Valve Morphogenesis-Brief Report. Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1732-1735 |
1 | J:158668 Qu X, Tompkins K, Batts LE, Puri M, Baldwin S, Abnormal embryonic lymphatic vessel development in Tie1 hypomorphic mice. Development. 2010 Apr;137(8):1285-95 |
1 | J:296443 Rondon-Galeano M, Skoczylas R, Bower NI, Simons C, Gordon E, Francois M, Koltowska K, Hogan BM, MAFB modulates the maturation of lymphatic vascular networks in mice. Dev Dyn. 2020 Oct;249(10):1201-1216 |
1 | J:249238 Roukens MG, Peterson-Maduro J, Padberg Y, Jeltsch M, Leppanen VM, Bos FL, Alitalo K, Schulte-Merker S, Schulte D, Functional Dissection of the CCBE1 Protein: A Crucial Requirement for the Collagen Repeat Domain. Circ Res. 2015 May 8;116(10):1660-9 |
1 | J:209095 Rubin AN, Kessaris N, PROX1: a lineage tracer for cortical interneurons originating in the lateral/caudal ganglionic eminence and preoptic area. PLoS One. 2013;8(10):e77339 |
1 | J:181330 Sabine A, Agalarov Y, Maby-El Hajjami H, Jaquet M, Hagerling R, Pollmann C, Bebber D, Pfenniger A, Miura N, Dormond O, Calmes JM, Adams RH, Makinen T, Kiefer F, Kwak BR, Petrova TV, Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation. Dev Cell. 2012 Feb 14;22(2):430-45 |
1 | J:308685 Scallan JP, Knauer LA, Hou H, Castorena-Gonzalez JA, Davis MJ, Yang Y, Foxo1 deletion promotes the growth of new lymphatic valves. J Clin Invest. 2021 Jul 15;131(14) |
1 | J:316218 Schoof M, Hellwig M, Harrison L, Holdhof D, Lauffer MC, Niesen J, Virdi S, Indenbirken D, Schuller U, The basic helix-loop-helix transcription factor TCF4 impacts brain architecture as well as neuronal morphology and differentiation. Eur J Neurosci. 2020 Jun;51(11):2219-2235 |
2 | J:142359 Seah C, Levy MA, Jiang Y, Mokhtarzada S, Higgs DR, Gibbons RJ, Berube NG, Neuronal death resulting from targeted disruption of the Snf2 protein ATRX is mediated by p53. J Neurosci. 2008 Nov 19;28(47):12570-80 |
1* | J:271100 Shen B, Shang Z, Wang B, Zhang L, Zhou F, Li T, Chu M, Jiang H, Wang Y, Qiao T, Zhang J, Sun W, Kong X, He Y, Genetic dissection of tie pathway in mouse lymphatic maturation and valve development. Arterioscler Thromb Vasc Biol. 2014 Jun;34(6):1221-30 |
1* | J:145448 Shimoda H, Immunohistochemical demonstration of Angiopoietin-2 in lymphatic vascular development. Histochem Cell Biol. 2009 Feb;131(2):231-8 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:122566 Simirskii VN, Wang Y, Duncan MK, Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype. Dev Biol. 2007 Jun 15;306(2):658-68 |
1 | J:206876 Song JY, Park R, Kim JY, Hughes L, Lu L, Kim S, Johnson RL, Cho SH, Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev Biol. 2014 Feb 15;386(2):281-90 |
1 | J:158959 Srinivasan RS, Geng X, Yang Y, Wang Y, Mukatira S, Studer M, Porto MP, Lagutin O, Oliver G, The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells. Genes Dev. 2010 Apr 1;24(7):696-707 |
1 | J:177488 Srinivasan RS, Oliver G, Prox1 dosage controls the number of lymphatic endothelial cell progenitors and the formation of the lymphovenous valves. Genes Dev. 2011 Oct 15;25(20):2187-97 |
1 | J:194385 Steffes G, Lorente-Canovas B, Pearson S, Brooker RH, Spiden S, Kiernan AE, Guenet JL, Steel KP, Mutanlallemand (mtl) and Belly Spot and Deafness (bsd) are two new mutations of Lmx1a causing severe cochlear and vestibular defects. PLoS One. 2012;7(11):e51065 |
1 | J:278572 Stone OA, Stainier DYR, Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium. Dev Cell. 2019 Jul 22;50(2):247-255.e3 |
1* | J:203065 Sugiyama T, Osumi N, Katsuyama Y, The germinal matrices in the developing dentate gyrus are composed of neuronal progenitors at distinct differentiation stages. Dev Dyn. 2013 Dec;242(12):1442-53 |
1 | J:216104 Sugiyama T, Osumi N, Katsuyama Y, A novel cell migratory zone in the developing hippocampal formation. J Comp Neurol. 2014 Oct 15;522(15):3520-38 |
1 | J:343554 Sun Q, Li J, Ma J, Zheng Y, Ju R, Li X, Ren X, Huang L, Chen R, Tan X, Luo L, JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development. Invest Ophthalmol Vis Sci. 2023 Dec 1;64(15):15 |
1 | J:327277 Venkataramanappa S, Saaber F, Abe P, Schutz D, Kumar PA, Stumm R, Cxcr4 and Ackr3 regulate allocation of caudal ganglionic eminence-derived interneurons to superficial cortical layers. Cell Rep. 2022 Aug 2;40(5):111157 |
1 | J:221658 Vithayathil J, Pucilowska J, Goodnough LH, Atit RP, Landreth GE, Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation. J Neurosci. 2015 Apr 29;35(17):6836-48 |
1 | J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34 |
1 | J:237534 Wang Y, Baeyens N, Corti F, Tanaka K, Fang JS, Zhang J, Jin Y, Coon B, Hirschi KK, Schwartz MA, Simons M, Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development. Development. 2016 Dec 01;143(23):4441-4451 |
1 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
1 | J:282590 Wei S, Du H, Li Z, Tao G, Xu Z, Song X, Shang Z, Su Z, Chen H, Wen Y, Liu G, You Y, Zhang Z, Yang Z, Transcription factors Sp8 and Sp9 regulate the development of caudal ganglionic eminence-derived cortical interneurons. J Comp Neurol. 2019 Dec 1;527(17):2860-2874 |
1 | J:159315 Xie Z, Ma X, Ji W, Zhou G, Lu Y, Xiang Z, Wang YX, Zhang L, Hu Y, Ding YQ, Zhang WJ, Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6510-5 |
1 | J:285763 Xu M, Han X, Liu R, Li Y, Qi C, Yang Z, Zhao C, Gao J, PDK1 Deficit Impairs the Development of the Dentate Gyrus in Mice. Cereb Cortex. 2019 Mar 1;29(3):1185-1198 |
1 | J:319651 Yamada M, Clark J, McClelland C, Capaldo E, Ray A, Iulianella A, Cux2 activity defines a subpopulation of perinatal neurogenic progenitors in the hippocampus. Hippocampus. 2015 Feb;25(2):253-67 |
2 | J:278463 Yang Y, Cha B, Motawe ZY, Srinivasan RS, Scallan JP, VE-Cadherin Is Required for Lymphatic Valve Formation and Maintenance. Cell Rep. 2019;28(9):2397-2412 |
1 | J:241335 Yang Y, Enis D, Zheng H, Chia S, Yang J, Chen M, Dhillon V, Papayannapoulou T, Kahn ML, Cell Adhesion Mediated by VCAM-ITGalpha9 Interactions Enables Lymphatic Development. Arterioscler Thromb Vasc Biol. 2015 May;35(5):1179-89 |
1 | J:350084 Zhang L, Liu X, Li W, Liu K, Zhang J, Liu X, Wang J, Integrative transcriptomic profiling of ncRNAs and mRNAs in developing mouse lens. Front Genet. 2024;15:1405715 |
1* | J:143210 Zhou CJ, Molotkov A, Song L, Li Y, Pleasure DE, Pleasure SJ, Wang YZ, Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes. Dev Dyn. 2008 Dec;237(12):3681-9 |
1 | J:109778 Zhou CJ, Pinson KI, Pleasure SJ, Severe defects in dorsal thalamic development in low-density lipoprotein receptor-related protein-6 mutants. J Neurosci. 2004 Sep 1;24(35):7632-9 |
1 | J:196696 Zou Z, Enis DR, Bui H, Khandros E, Kumar V, Jakus Z, Thom C, Yang Y, Dhillon V, Chen M, Lu M, Weiss MJ, Kahn ML, The secreted lymphangiogenic factor CCBE1 is essential for fetal liver erythropoiesis. Blood. 2013 Apr 18;121(16):3228-36 |
Prpf38b PRP38 pre-mRNA processing factor 38 (yeast) domain containing B (Synonyms: 1110021E09Rik) | |
Results | Reference |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Prpf39 pre-mRNA processing factor 39 (Synonyms: MGC:37077, Srcs1) | |
Results | Reference |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Prph peripherin (Synonyms: Prph1) | |
Results | Reference |
1 | J:103452 Abbott MA, Joksimovic M, Tuggle CK, Ectopic HOXA5 expression results in abnormal differentiation, migration and p53-independent cell death of superficial dorsal horn neurons. Brain Res Dev Brain Res. 2005 Oct 6;159(2):87-97 |
1 | J:166770 Coppola E, d'Autreaux F, Rijli FM, Brunet JF, Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation. Development. 2010 Dec;137(24):4211-20 |
1 | J:126634 Coppola E, Pattyn A, Guthrie SC, Goridis C, Studer M, Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation. EMBO J. 2005 Dec 21;24(24):4392-403 |
1* | J:194894 Couesnon A, Offner N, Bernard V, Chaverot N, Backer S, Dimitrov A, Perez F, Molgo J, Bloch-Gallego E, CLIPR-59: a protein essential for neuromuscular junction stability during mouse late embryonic development. Development. 2013 Apr;140(7):1583-93 |
1 | J:54791 Faussone-Pellegrini MS, Matini P, DeFelici M, The cytoskeleton of the myenteric neurons during murine embryonic life. Anat Embryol (Berl). 1999 May;199(5):459-69 |
1 | J:315755 Hancock ML, Nowakowski DW, Role LW, Talmage DA, Flanagan JG, Type III neuregulin 1 regulates pathfinding of sensory axons in the developing spinal cord and periphery. Development. 2011 Nov;138(22):4887-98 |
1* | J:95356 Kettunen P, Loes S, Furmanek T, Fjeld K, Kvinnsland IH, Behar O, Yagi T, Fujisawa H, Vainio S, Taniguchi M, Luukko K, Coordination of trigeminal axon navigation and patterning with tooth organ formation: epithelial-mesenchymal interactions, and epithelial Wnt4 and Tgf{beta}1 regulate semaphorin 3a expression in the dental mesenchyme. Development. 2005 Jan;132(2):323-334 |
1 | J:151258 Kolterud A, Grosse AS, Zacharias WJ, Walton KD, Kretovich KE, Madison BB, Waghray M, Ferris JE, Hu C, Merchant JL, Dlugosz AA, Kottmann AH, Gumucio DL, Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning. Gastroenterology. 2009 Aug;137(2):618-28 |
1 | J:204198 Memi F, Abe P, Cariboni A, MacKay F, Parnavelas JG, Stumm R, CXC chemokine receptor 7 (CXCR7) affects the migration of GnRH neurons by regulating CXCL12 availability. J Neurosci. 2013 Oct 30;33(44):17527-37 |
1 | J:201154 Meziane H, Fraulob V, Riet F, Krezel W, Selloum M, Geffarth M, Acampora D, Herault Y, Simeone A, Brand M, Dolle P, Rhinn M, The homeodomain factor Gbx1 is required for locomotion and cell specification in the dorsal spinal cord. PeerJ. 2013;1:e142 |
1 | J:76685 Ohshima T, Ogawa M, Takeuchi K, Takahashi S, Kulkarni AB, Mikoshiba K, Cyclin-dependent kinase 5/p35 contributes synergistically with Reelin/Dab1 to the positioning of facial branchiomotor and inferior olive neurons in the developing mouse hindbrain. J Neurosci. 2002 May 15;22(10):4036-44 |
1 | J:84976 Pattyn A, Vallstedt A, Dias JM, Sander M, Ericson J, Complementary roles for Nkx6 and Nkx2 class proteins in the establishment of motoneuron identity in the hindbrain. Development. 2003 Sep;130(17):4149-59 |
1 | J:221833 Prakash A, Udager AM, Saenz DA, Gumucio DL, Roles for Nkx2-5 and Gata3 in the ontogeny of the murine smooth muscle gastric ligaments. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 15;307(4):G430-6 |
1* | J:268254 Rich CA, Perera SN, Andratschke J, Stolt CC, Buehler DP, Southard-Smith EM, Wegner M, Britsch S, Baker CVH, Olfactory ensheathing cells abutting the embryonic olfactory bulb express Frzb, whose deletion disrupts olfactory axon targeting. Glia. 2018 Dec;66(12):2617-2631 |
1 | J:223063 Rogers SW, Tvrdik P, Capecchi MR, Gahring LC, Prenatal ablation of nicotinic receptor alpha7 cell lineages produces lumbosacral spina bifida the severity of which is modified by choline and nicotine exposure. Am J Med Genet A. 2012 May;158A(5):1135-44 |
1 | J:310449 Shrestha A, Moe K, Luukko K, Taniguchi M, Kettunen P, Sema3A chemorepellant regulates the timing and patterning of dental nerves during development of incisor tooth germ. Cell Tissue Res. 2014 Jul;357(1):15-29 |
1* | J:286599 Song NN, Ma P, Zhang Q, Zhang L, Wang H, Zhang L, Zhu L, He CH, Mao B, Ding YQ, Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199 |
1 | J:124714 Subramanian V, Feng Y, A new role for angiogenin in neurite growth and pathfinding: implications for amyotrophic lateral sclerosis. Hum Mol Genet. 2007 Jun 15;16(12):1445-53 |
1 | J:228275 Udager AM, Prakash A, Saenz DA, Schinke M, Moriguchi T, Jay PY, Lim KC, Engel JD, Gumucio DL, Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3. Gastroenterology. 2014 Jan;146(1):157-65.e10 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
Prph2 peripherin 2 (Synonyms: Nmf193, Rd2, rds, Tspan22) | |
Results | Reference |
1* | J:120114 Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY, A biphasic pattern of gene expression during mouse retina development. BMC Dev Biol. 2006;6:48 |
Prr12 proline rich 12 | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Prr15 proline rich 15 (Synonyms: E130201N16Rik, G90) | |
Results | Reference |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Prrc2c proline-rich coiled-coil 2C (Synonyms: 1810043M20Rik, 9630039I18Rik, Bat2d, Bat2l2, mKIAA1096) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Prrx1 paired related homeobox 1 (Synonyms: A230024N07Rik, K-2, mHox, mHox, MHox1, Pmx1, Prx1) | |
Results | Reference |
3* | J:72551 Chesterman ES, Gainey GD, Varn AC, Peterson RE Jr, Kern MJ, Investigation of Prx1 protein expression provides evidence for conservation of cardiac-specific posttranscriptional regulation in vertebrates. Dev Dyn. 2001 Nov;222(3):459-70 |
1* | J:73653 Chesterman ES, Kern MJ, Comparative analysis of Prx1 and Prx2 expression in mice provides evidence for incomplete compensation. Anat Rec. 2002 Jan 1;266(1):1-4 |
1* | J:131364 Cretekos CJ, Wang Y, Green ED, Martin JF, Rasweiler JJ 4th, Behringer RR, Regulatory divergence modifies limb length between mammals. Genes Dev. 2008 Jan 15;22(2):141-51 |
1* | J:337818 Currie JD, Grosser L, Murawala P, Schuez M, Michel M: Tanaka EM, Sandoval-Guzman T, The Prrx1 limb enhancer marks an adult subpopulation of injury-responsive dermal fibroblasts. Biol Open. 2019;8(7):bio043711 |
2* | J:3255 Kern MJ, Witte DP, Valerius MT, Aronow BJ, Potter SS, A novel murine homeobox gene isolated by a tissue specific PCR cloning strategy. Nucleic Acids Res. 1992 Oct 11;20(19):5189-95 |
1 | J:326535 Petitpre C, Faure L, Uhl P, Fontanet P, Filova I, Pavlinkova G, Adameyko I, Hadjab S, Lallemend F, Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification. Nat Commun. 2022 Jul 5;13(1):3878 |
1* | J:50488 ten Berge D, Brouwer A, Korving J, Martin JF, Meijlink F, Prx1 and Prx2 in skeletogenesis: roles in the craniofacial region, inner ear and limbs. Development. 1998 Oct;125(19):3831-42 |
Prrx2 paired related homeobox 2 (Synonyms: Prx2, S8) | |
Results | Reference |
1* | J:73653 Chesterman ES, Kern MJ, Comparative analysis of Prx1 and Prx2 expression in mice provides evidence for incomplete compensation. Anat Rec. 2002 Jan 1;266(1):1-4 |
1* | J:163272 Haugas M, Lillevali K, Hakanen J, Salminen M, Gata2 is required for the development of inner ear semicircular ducts and the surrounding perilymphatic space. Dev Dyn. 2010 Sep;239(9):2452-69 |
1* | J:44495 Karg H, Burger EH, Lyaruu DM, Bronckers AL, Woltgens JH, Spatiotemporal expression of the homeobox gene S8 during mouse tooth development. Arch Oral Biol. 1997 Sep;42(9):625-31 |
1* | J:239225 Scott KK, Norris RA, Potter SS, Norrington DW, Baybo MA, Hicklin DM, Kern MJ, GeneChip microarrays facilitate identification of Protease Nexin-1 as a target gene of the Prx2 (S8) homeoprotein. DNA Cell Biol. 2003 Feb;22(2):95-105 |
1* | J:50488 ten Berge D, Brouwer A, Korving J, Martin JF, Meijlink F, Prx1 and Prx2 in skeletogenesis: roles in the craniofacial region, inner ear and limbs. Development. 1998 Oct;125(19):3831-42 |
Prss2 serine protease 2 (Synonyms: Ta, Tesp4, Try2, TRY8, TRYP) | |
Results | Reference |
2* | J:50645 Petrucco S, Wellauer PK, Hagenbuchle O, The DNA-binding activity of transcription factor PTF1 parallels the synthesis of pancreas-specific mRNAs during mouse development. Mol Cell Biol. 1990 Jan;10(1):254-64 |
Prss8 serine protease 8 (prostasin) (Synonyms: 2410039E18Rik, CAP1, fr, mCAP1) | |
Results | Reference |
1* | J:117240 Netzel-Arnett S, Currie BM, Szabo R, Lin CY, Chen LM, Chai KX, Antalis TM, Bugge TH, List K, Evidence for a matriptase-prostasin proteolytic cascade regulating terminal epidermal differentiation. J Biol Chem. 2006 Nov 3;281(44):32941-5 |
Prss27 serine protease 27 (Synonyms: CAPH2, marapsin, Mpn, Pancreasin) | |
Results | Reference |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
Prss33 serine protease 33 (Synonyms: Eos, mT6, tryptase-6) | |
Results | Reference |
1 | J:240536 Martin-Ibanez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion-Poll L, Herranz C, Esgleas M, Garcia-Diaz Barriga G, Edel MJ, Vicario-Abejon C, Alberch J, Girault JA, Chan S, Kastner P, Canals JM, Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017 Apr 15;144(8):1566-1577 |
Prss34 serine protease 34 (Synonyms: mast cell protease 11, mMcp-11) | |
Results | Reference |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Prss35 serine protease 35 (Synonyms: 6030424L22Rik) | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
Prss50 serine protease 50 (Synonyms: Tsp50) | |
Results | Reference |
1* | J:306369 Ai HH, Liu B, Yang MT, Zuo QQ, Song ZB, Bao YL, Sun LG, Zhou L, Li YX, Expression and effects of TSP50 in mouse embryo and cardiac myocyte development. Biochem Biophys Res Commun. 2018 Jul 12;502(2):283-288 |
Prss56 serine protease 56 (Synonyms: 1700027L20Rik, Prss56) | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Prx periaxin (Synonyms: L-Periaxin) | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Psap prosaposin (Synonyms: SGP-1) | |
Results | Reference |
2 | J:94199 Cohen T, Ravid L, Altman N, Madar-Shapiro L, Fein A, Weil M, Horowitz M, Conservation of expression and alternative splicing in the prosaposin gene. Brain Res Mol Brain Res. 2004 Oct 22;129(1-2):8-19 |
Psca prostate stem cell antigen (Synonyms: 2210408B04Rik) | |
Results | Reference |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1* | J:68524 Ross S, Spencer SD, Lasky LA, Koeppen H, Selective expression of murine prostate stem cell antigen in fetal and adult tissues and the transgenic adenocarcinoma of the mouse prostate model of prostate carcinogenesis. Am J Pathol. 2001 Mar;158(3):809-16 |
Psen1 presenilin 1 (Synonyms: Ad3h, presenilin-1, PS-1, PS1, S182) | |
Results | Reference |
1 | J:36884 Lee MK, Slunt HH, Martin LJ, Thinakaran G, Kim G, Gandy SE, Seeger M, Koo E, Price DL, Sisodia SS, Expression of presenilin 1 and 2 (PS1 and PS2) in human and murine tissues. J Neurosci. 1996 Dec 1;16(23):7513-25 |
Psen2 presenilin 2 (Synonyms: Ad4h, ALG-3, PS-2, PS2) | |
Results | Reference |
1 | J:236794 Ezratty EJ, Pasolli HA, Fuchs E, A Presenilin-2-ARF4 trafficking axis modulates Notch signaling during epidermal differentiation. J Cell Biol. 2016 Jul 4;214(1):89-101 |
Psenen presenilin enhancer gamma secretase subunit (Synonyms: 1700023M09Rik, Pen2) | |
Results | Reference |
1 | J:325764 Xia Y, Zhang Y, Xu M, Zou X, Gao J, Ji MH, Chen G, Presenilin enhancer 2 is crucial for the transition of apical progenitors into neurons but into not basal progenitors in the developing hippocampus. Development. 2022 May 15;149(10):dev200272 |
Psg17 pregnancy specific beta-1-glycoprotein 17 (Synonyms: Cea-2, Cea2, mmCGM5) | |
Results | Reference |
1 | J:37260 Kromer B, Finkenzeller D, Wessels J, Dveksler G, Thompson J, Zimmermann W, Coordinate expression of splice variants of the murine pregnancy-specific glycoprotein (PSG) gene family during placental development. Eur J Biochem. 1996 Dec 1;242(2):280-7 |
Psg18 pregnancy specific beta-1-glycoprotein 18 (Synonyms: Cea-3, Cea3, mmCGM6) | |
Results | Reference |
1 | J:37260 Kromer B, Finkenzeller D, Wessels J, Dveksler G, Thompson J, Zimmermann W, Coordinate expression of splice variants of the murine pregnancy-specific glycoprotein (PSG) gene family during placental development. Eur J Biochem. 1996 Dec 1;242(2):280-7 |
1 | J:63500 Wessells J, Wessner D, Parsells R, White K, Finkenzeller D, Zimmermann W, Dveksler G, Pregnancy specific glycoprotein 18 induces IL-10 expression in murine macrophages. Eur J Immunol. 2000 Jul;30(7):1830-40 |
Psg19 pregnancy specific beta-1-glycoprotein 19 (Synonyms: Cea-4, Cea4, CGM7) | |
Results | Reference |
1 | J:37260 Kromer B, Finkenzeller D, Wessels J, Dveksler G, Thompson J, Zimmermann W, Coordinate expression of splice variants of the murine pregnancy-specific glycoprotein (PSG) gene family during placental development. Eur J Biochem. 1996 Dec 1;242(2):280-7 |
Psma7 proteasome subunit alpha 7 (Synonyms: C6-I) | |
Results | Reference |
1 | J:162790 Sasaki K, Hamazaki J, Koike M, Hirano Y, Komatsu M, Uchiyama Y, Tanaka K, Murata S, PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis. Mol Cell Biol. 2010 Aug;30(15):3864-74 |
Psmb1 proteasome (prosome, macropain) subunit, beta type 1 (Synonyms: Lmpc5) | |
Results | Reference |
1 | J:162790 Sasaki K, Hamazaki J, Koike M, Hirano Y, Komatsu M, Uchiyama Y, Tanaka K, Murata S, PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis. Mol Cell Biol. 2010 Aug;30(15):3864-74 |
Psmb11 proteasome (prosome, macropain) subunit, beta type, 11 (Synonyms: 5830406J20Rik, beta5t) | |
Results | Reference |
1 | J:290414 Li J, Gordon J, Chen ELY, Xiao S, Wu L, Zuniga-Pflucker JC, Manley NR, NOTCH1 signaling establishes the medullary thymic epithelial cell progenitor pool during mouse fetal development. Development. 2020 Jun 22;147(12):dev178988 |
Psmc2 proteasome (prosome, macropain) 26S subunit, ATPase 2 | |
Results | Reference |
1* | J:39617 Allen J, Colleaux L, Davidson D, Graham E, Lee M, Hill R, Abbott C , Gordon C, Expression and mapping of the mouse S7/Pmsc2 gene, homolog of an essential mitotic gene in yeast. Mamm Genome. 1997 May;8(5):352-4 |
Psmc3ip proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein (Synonyms: HOP2, Tbpip) | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Psmc5 protease (prosome, macropain) 26S subunit, ATPase 5 (Synonyms: mSUG1, Rpt6) | |
Results | Reference |
1 | J:162790 Sasaki K, Hamazaki J, Koike M, Hirano Y, Komatsu M, Uchiyama Y, Tanaka K, Murata S, PAC1 gene knockout reveals an essential role of chaperone-mediated 20S proteasome biogenesis and latent 20S proteasomes in cellular homeostasis. Mol Cell Biol. 2010 Aug;30(15):3864-74 |
Psmd8 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 (Synonyms: 6720456J22Rik, C76433) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Psmd14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 (Synonyms: 2610312C03Rik, 3200001M20Rik, Pad1, POH1) | |
Results | Reference |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Pspc1 paraspeckle protein 1 (Synonyms: 5730470C09Rik, PSP1) | |
Results | Reference |
1* | J:285730 Major AT, Hogarth CA, Young JC, Kurihara Y, Jans DA, Loveland KL, Dynamic paraspeckle component localisation during spermatogenesis. Reproduction. 2019 Sep;158(3):267-280 |
Psrc1 proline/serine-rich coiled-coil 1 (Synonyms: 5430413I02Rik, DDA3) | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Ptbp1 polypyrimidine tract binding protein 1 (Synonyms: hnRNP I, Ptb) | |
Results | Reference |
1* | J:265269 Dhananjaya D, Hung KY, Tarn WY, RBM4 Modulates Radial Migration via Alternative Splicing of Dab1 during Cortex Development. Mol Cell Biol. 2018 Jun 15;38(12) |
2 | J:297779 Lin L, Zhang M, Stoilov P, Chen L, Zheng S, Developmental Attenuation of Neuronal Apoptosis by Neural-Specific Splicing of Bak1 Microexon. Neuron. 2020 Sep 23;107(6):1180-1196.e8 |
2 | J:213479 Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, Yoshida N, PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Cereb Cortex. 2013 Aug;23(8):1824-35 |
1* | J:223915 Suckale J, Wendling O, Masjkur J, Jager M, Munster C, Anastassiadis K, Stewart AF, Solimena M, PTBP1 is required for embryonic development before gastrulation. PLoS One. 2011;6(2):e16992 |
Ptbp2 polypyrimidine tract binding protein 2 (Synonyms: brPTB) | |
Results | Reference |
1* | J:265269 Dhananjaya D, Hung KY, Tarn WY, RBM4 Modulates Radial Migration via Alternative Splicing of Dab1 during Cortex Development. Mol Cell Biol. 2018 Jun 15;38(12) |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
2 | J:213479 Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, Yoshida N, PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Cereb Cortex. 2013 Aug;23(8):1824-35 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Ptch1 patched 1 (Synonyms: A230106A15Rik, Patched 1, Ptc, Ptc1, wig) | |
Results | Reference |
1 | J:90567 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 2004 May 1;18(9):1072-87 |
1 | J:346119 Amano K, Okuzaki D, Kitaoka Y, Kato S, Fujiwara M, Tanaka S, Iida S, Pth1r in Neural Crest Cells Regulates Nasal Cartilage Differentiation. J Dent Res. 2024 Mar;103(3):308-317 |
1 | J:337598 Au TYK, Yip RKH, Wynn SL, Tan TY, Fu A, Geng YH, Szeto IYY, Niu B, Yip KY, Cheung MCH, Lovell-Badge R, Cheah KSE, Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog-Wnt signaling, causing campomelia. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2208623119 |
1 | J:176604 Bell SM, Zhang L, Mendell A, Xu Y, Haitchi HM, Lessard JL, Whitsett JA, Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. Dev Biol. 2011 Oct 1;358(1):79-90 |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
2 | J:155396 Bellon E, Luyten FP, Tylzanowski P, delta-EF1 is a negative regulator of Ihh in the developing growth plate. J Cell Biol. 2009 Nov 30;187(5):685-99 |
2* | J:38383 Bellusci S, Furuta Y, Rush MG, Henderson R, Winnier G, Hogan BL, Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis. Development. 1997 Jan;124(1):53-63 |
1* | J:85724 Bendall AJ, Hu G, Levi G, Abate-Shen C, Dlx5 regulates chondrocyte differentiation at multiple stages. Int J Dev Biol. 2003 Jun;47(5):335-44 |
1* | J:88802 Berman DM, Desai N, Wang X, Karhadkar SS, Reynon M, Abate-Shen C, Beachy PA, Shen MM, Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis. Dev Biol. 2004 Mar 15;267(2):387-98 |
1* | J:168038 Bimonte S, De Angelis A, Quagliata L, Giusti F, Tammaro R, Dallai R, Ascenzi MG, Diez-Roux G, Franco B, Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol. 2011 Jan 15;349(2):179-91 |
2 | J:175458 Bren-Mattison Y, Hausburg M, Olwin BB, Growth of limb muscle is dependent on skeletal-derived Indian hedgehog. Dev Biol. 2011 Aug 15;356(2):486-95 |
2 | J:188176 Caparros-Martin JA, Valencia M, Reytor E, Pacheco M, Fernandez M, Perez-Aytes A, Gean E, Lapunzina P, Peters H, Goodship JA, Ruiz-Perez VL, The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia. Hum Mol Genet. 2013 Jan 1;22(1):124-39 |
1 | J:223109 Choi JJ, Ting CT, Trogrlic L, Milevski SV, Familari M, Martinez G, de Iongh RU, A role for smoothened during murine lens and cornea development. PLoS One. 2014;9(9):e108037 |
3 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1* | J:150375 Cobourne MT, Xavier GM, Depew M, Hagan L, Sealby J, Webster Z, Sharpe PT, Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome. Dev Biol. 2009 Jul 1;331(1):38-49 |
1 | J:111051 Cui CY, Hashimoto T, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9142-7 |
1 | J:230611 Dierker T, Bachvarova V, Krause Y, Li JP, Kjellen L, Seidler DG, Vortkamp A, Altered heparan sulfate structure in Glce(-/-) mice leads to increased Hedgehog signaling in endochondral bones. Matrix Biol. 2016 Jan;49:82-92 |
1 | J:202337 Estrada KD, Wang W, Retting KN, Chien CT, Elkhoury FF, Heuchel R, Lyons KM, Smad7 regulates terminal maturation of chondrocytes in the growth plate. Dev Biol. 2013 Oct 15;382(2):375-84 |
1 | J:147878 Gao B, Hu J, Stricker S, Cheung M, Ma G, Law KF, Witte F, Briscoe J, Mundlos S, He L, Cheah KS, Chan D, A mutation in Ihh that causes digit abnormalities alters its signalling capacity and range. Nature. 2009 Apr 30;458(7242):1196-200 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:74145 Gori F, Schipani E, Demay MB, Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development. J Cell Biochem. 2001 Apr 2-27;82(1):46-57 |
1 | J:117334 Gritli-Linde A, Hallberg K, Harfe BD, Reyahi A, Kannius-Janson M, Nilsson J, Cobourne MT, Sharpe PT, McMahon AP, Linde A, Abnormal hair development and apparent follicular transformation to mammary gland in the absence of hedgehog signaling. Dev Cell. 2007 Jan;12(1):99-112 |
2* | J:53317 Hall JM, Hooper JE, Finger TE, Expression of sonic hedgehog, patched, and Gli1 in developing taste papillae of the mouse. J Comp Neurol. 1999 Apr 5;406(2):143-55 |
1 | J:65293 Hebrok M, Kim SK, St Jacques B, McMahon AP, Melton DA, Regulation of pancreas development by hedgehog signaling. Development. 2000 Nov;127(22):4905-13 |
1 | J:98426 Hill TP, Spater D, Taketo MM, Birchmeier W, Hartmann C, Canonical Wnt/beta-Catenin Signaling Prevents Osteoblasts from Differentiating into Chondrocytes. Dev Cell. 2005 May;8(5):727-38 |
1 | J:104933 Hilton MJ, Gutierrez L, Martinez DA, Wells DE, EXT1 regulates chondrocyte proliferation and differentiation during endochondral bone development. Bone. 2005 Mar;36(3):379-86 |
1 | J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132 |
2 | J:175769 Hsu SH, Zhang X, Yu C, Li ZJ, Wunder JS, Hui CC, Alman BA, Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu. Development. 2011 Sep;138(17):3791-801 |
2 | J:160335 Huang X, Liu J, Ketova T, Fleming JT, Grover VK, Cooper MK, Litingtung Y, Chiang C, Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8422-7 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:108713 Itaranta P, Chi L, Seppanen T, Niku M, Tuukkanen J, Peltoketo H, Vainio S, Wnt-4 signaling is involved in the control of smooth muscle cell fate via Bmp-4 in the medullary stroma of the developing kidney. Dev Biol. 2006 May 15;293(2):473-83 |
1 | J:282774 Jia X, Min L, Zhu S, Zhang S, Huang X, Loss of sonic hedgehog gene leads to muscle development disorder and megaesophagus in mice. FASEB J. 2018 Oct;32(10):5703-5715 |
1 | J:260962 Kamiunten T, Ideno H, Shimada A, Arai Y, Terashima T, Tomooka Y, Nakamura Y, Nakashima K, Kimura H, Shinkai Y, Tachibana M, Nifuji A, Essential roles of G9a in cell proliferation and differentiation during tooth development. Exp Cell Res. 2017 Aug 15;357(2):202-210 |
1 | J:54912 Karlsson L, Bondjers C, Betsholtz C, Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle. Development. 1999 Jun;126(12):2611-21 |
1* | J:160585 Kesper DA, Didt-Koziel L, Vortkamp A, Gli2 activator function in preosteoblasts is sufficient to mediate Ihh-dependent osteoblast differentiation, whereas the repressor function of Gli2 is dispensable for endochondral ossification. Dev Dyn. 2010 Jun;239(6):1818-26 |
1 | J:155826 King P, Paul A, Laufer E, Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21185-90 |
2 | J:151258 Kolterud A, Grosse AS, Zacharias WJ, Walton KD, Kretovich KE, Madison BB, Waghray M, Ferris JE, Hu C, Merchant JL, Dlugosz AA, Kottmann AH, Gumucio DL, Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning. Gastroenterology. 2009 Aug;137(2):618-28 |
1 | J:336410 Koo HY, Kim MA, Min H, Hwang JY, Prajapati-DiNubila M, Kim KS, Matzuk MM, Park JW, Doetzlhofer A, Kim UK, Bok J, Follistatin regulates the specification of the apical cochlea responsible for low-frequency hearing in mammals. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2213099120 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1 | J:92212 Koziel L, Kunath M, Kelly OG, Vortkamp A, Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification. Dev Cell. 2004 Jun;6(6):801-13 |
1 | J:102948 Koziel L, Wuelling M, Schneider S, Vortkamp A, Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation. Development. 2005 Dec;132(23):5249-60 |
1 | J:147576 Kunisada M, Cui CY, Piao Y, Ko MS, Schlessinger D, Requirement for Shh and Fox family genes at different stages in sweat gland development. Hum Mol Genet. 2009 May 15;18(10):1769-78 |
1 | J:78990 Lamm ML, Catbagan WS, Laciak RJ, Barnett DH, Hebner CM, Gaffield W, Walterhouse D, Iannaccone P, Bushman W, Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation. Dev Biol. 2002 Sep 15;249(2):349-66 |
1 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
1 | J:112118 Lee Y, Miller HL, Russell HR, Boyd K, Curran T, McKinnon PJ, Patched2 modulates tumorigenesis in patched1 heterozygous mice. Cancer Res. 2006 Jul 15;66(14):6964-71 |
1 | J:178364 Lenton K, James AW, Manu A, Brugmann SA, Birker D, Nelson ER, Leucht P, Helms JA, Longaker MT, Indian hedgehog positively regulates calvarial ossification and modulates bone morphogenetic protein signaling. Genesis. 2011 Oct;49(10):784-96 |
1 | J:182649 Levi B, James AW, Nelson ER, Brugmann SA, Sorkin M, Manu A, Longaker MT, Role of Indian hedgehog signaling in palatal osteogenesis. Plast Reconstr Surg. 2011 Mar;127(3):1182-90 |
1 | J:92189 Lewis PM, Gritli-Linde A, Smeyne R, Kottmann A, McMahon AP, Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum. Dev Biol. 2004 Jun 15;270(2):393-410 |
1 | J:214993 Lin C, Chen MH, Yao E, Song H, Gacayan R, Hui CC, Chuang PT, Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development. Dev Biol. 2014 Aug 15;392(2):324-33 |
1 | J:75879 Liu Z, Xu J, Colvin JS, Ornitz DM, Coordination of chondrogenesis and osteogenesis by fibroblast growth factor 18. Genes Dev. 2002 Apr 1;16(7):859-69 |
1 | J:88635 Long F, Chung UI, Ohba S, McMahon J, Kronenberg HM, McMahon AP, Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development. 2004 Mar;131(6):1309-18 |
1* | J:73071 Long F, Zhang XM, Karp S, Yang Y, McMahon AP, Genetic manipulation of hedgehog signaling in the endochondral skeleton reveals a direct role in the regulation of chondrocyte proliferation. Development. 2001 Dec;128(24):5099-108 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:236373 Ludtke TH, Rudat C, Wojahn I, Weiss AC, Kleppa MJ, Kurz J, Farin HF, Moon A, Christoffels VM, Kispert A, Tbx2 and Tbx3 Act Downstream of Shh to Maintain Canonical Wnt Signaling during Branching Morphogenesis of the Murine Lung. Dev Cell. 2016 Oct 24;39(2):239-253 |
1 | J:348792 Mead TJ, Bhutada S, Foulcer SJ, Peruzzi N, Nelson CM, Seifert DE, Larkin J, Tran-Lundmark K, Filmus J, Apte SS, Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development. Matrix Biol. 2024 May 13; |
1 | J:218941 Meier F, Giesert F, Delic S, Faus-Kessler T, Matheus F, Simeone A, Holter SM, Kuhn R, Weisenhorn DM, Wurst W, Prakash N, FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS One. 2014;9(7):e101124 |
1* | J:86666 Michno K, Boras-Granic K, Mill P, Hui CC, Hamel PA, Shh expression is required for embryonic hair follicle but not mammary gland development. Dev Biol. 2003 Dec 1;264(1):153-65 |
1 | J:205339 Mis EK, Liem KF Jr, Kong Y, Schwartz NB, Domowicz M, Weatherbee SD, Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length. Dev Biol. 2014 Jan 1;385(1):67-82 |
1 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1 | J:170582 Mundy C, Yasuda T, Kinumatsu T, Yamaguchi Y, Iwamoto M, Enomoto-Iwamoto M, Koyama E, Pacifici M, Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine. Dev Biol. 2011 Mar 1;351(1):70-81 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1 | J:144348 Ohazama A, Johnson EB, Ota MS, Choi HJ, Porntaveetus T, Oommen S, Itoh N, Eto K, Gritli-Linde A, Herz J, Sharpe PT, Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One. 2008;3(12):e4092 |
2 | J:183783 Ortega MC, Cases O, Merchan P, Kozyraki R, Clemente D, de Castro F, Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development. Glia. 2012 May;60(6):851-66 |
2 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1 | J:324528 Qu R, Gupta K, Dong D, Jiang Y, Landa B, Saez C, Strickland G, Levinsohn J, Weng PL, Taketo MM, Kluger Y, Myung P, Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients. Dev Cell. 2022 Apr 25;57(8):1053-1067.e5 |
1 | J:177268 Radzikinas K, Aven L, Jiang Z, Tran T, Paez-Cortez J, Boppidi K, Lu J, Fine A, Ai X, A Shh/miR-206/BDNF Cascade Coordinates Innervation and Formation of Airway Smooth Muscle. J Neurosci. 2011 Oct 26;31(43):15407-15 |
1* | J:130163 Ratzka A, Kalus I, Moser M, Dierks T, Mundlos S, Vortkamp A, Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development. Dev Dyn. 2008 Feb;237(2):339-53 |
1 | J:147287 Retting KN, Song B, Yoon BS, Lyons KM, BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation. Development. 2009 Apr;136(7):1093-104 |
1 | J:163175 Rice DP, Connor EC, Veltmaat JM, Lana-Elola E, Veistinen L, Tanimoto Y, Bellusci S, Rice R, Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation. Hum Mol Genet. 2010 Sep 1;19(17):3457-67 |
1 | J:124105 Ruiz-Perez VL, Blair HJ, Rodriguez-Andres ME, Blanco MJ, Wilson A, Liu YN, Miles C, Peters H, Goodship JA, Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. Development. 2007 Aug;134(16):2903-12 |
1 | J:340421 Ruscitto A, Chen P, Tosa I, Wang Z, Zhou G, Safina I, Wei R, Morel MM, Koch A, Forman M, Reeve G, Lecholop MK, Wilson M, Bonthius D, Chen M, Ono M, Wang TC, Yao H, Embree MC, Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity. Cell Stem Cell. 2023 Sep 7;30(9):1179-1198.e7 |
1* | J:143455 Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Al Awqati Q, Ballabio A, Karsenty G, Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification. Genes Dev. 2008 Oct 1;22(19):2645-50 |
1 | J:284493 Sharon N, Vanderhooft J, Straubhaar J, Mueller J, Chawla R, Zhou Q, Engquist EN, Trapnell C, Gifford DK, Melton DA, Wnt Signaling Separates the Progenitor and Endocrine Compartments during Pancreas Development. Cell Rep. 2019 May 21;27(8):2281-2291.e5 |
1* | J:85949 Shikama N, Lutz W, Kretzschmar R, Sauter N, Roth JF, Marino S, Wittwer J, Scheidweiler A, Eckner R, Essential function of p300 acetyltransferase activity in heart, lung and small intestine formation. EMBO J. 2003 Oct 1;22(19):5175-85 |
1* | J:80666 Smits P, Li P, Mandel J, Zhang Z, Deng JM, Behringer RR, de Croumbrugghe B, Lefebvre V, The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001 Aug;1(2):277-90 |
1 | J:361958 Straube P, Beckers A, Jany UWH, Bergmann F, Ludtke TH, Rudat C, Trowe MO, Peters I, Klopf MG, Mamo TM, Kispert A, Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter. Development. 2025 Feb 1;152(3) |
1 | J:191584 Sueyoshi T, Yamamoto K, Akiyama H, Conditional deletion of Tgfbr2 in hypertrophic chondrocytes delays terminal chondrocyte differentiation. Matrix Biol. 2012 Jul;31(6):352-9 |
1 | J:144194 Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72 |
1 | J:159209 Tornqvist G, Sandberg A, Hagglund AC, Carlsson L, Cyclic expression of lhx2 regulates hair formation. PLoS Genet. 2010;6(4):e1000904 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1 | J:324690 Wang H, Zheng C, Lu W, He T, Fan J, Wang C, Jie Q, Chan D, Cheah KSE, Yang L, Hedgehog signaling orchestrates cartilage-to-bone transition independently of Smoothened. Matrix Biol. 2022 Apr 23; |
1 | J:82377 Watkins DN, Berman DM, Burkholder SG, Wang B, Beachy PA, Baylin SB, Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer. Nature. 2003 Mar 20;422(6929):313-7 |
1 | J:168036 Wells KL, Mou C, Headon DJ, Tucker AS, Defects and rescue of the minor salivary glands in Eda pathway mutants. Dev Biol. 2011 Jan 15;349(2):137-46 |
1 | J:196290 Wheway G, Abdelhamed Z, Natarajan S, Toomes C, Inglehearn C, Johnson CA, Aberrant Wnt signalling and cellular over-proliferation in a novel mouse model of Meckel-Gruber syndrome. Dev Biol. 2013 May 1;377(1):55-66 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1 | J:149459 Wuelling M, Kaiser FJ, Buelens LA, Braunholz D, Shivdasani RA, Depping R, Vortkamp A, Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. Dev Biol. 2009 Apr 1;328(1):40-53 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
2 | J:282462 Yabut OR, Ng HX, Fernandez G, Yoon K, Kuhn J, Pleasure SJ, Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors. J Dev Biol. 2016 Dec;4(4) |
1 | J:116953 Yamago G, Takata Y, Furuta I, Urase K, Momoi T, Huh N, Suppression of hair follicle development inhibits induction of sonic hedgehog, patched, and patched-2 in hair germs in mice. Arch Dermatol Res. 2001 Sep;293(9):435-41 |
1 | J:360708 Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K, Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase. Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2320070121 |
1 | J:93296 Yu H, Wessels A, Chen J, Phelps AL, Oatis J, Tint GS, Patel SB, Late gestational lung hypoplasia in a mouse model of the Smith-Lemli-Opitz syndrome. BMC Dev Biol. 2004 Mar 2;4(1):1 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
1 | J:172282 Zhou ZQ, Shung CY, Ota S, Akiyama H, Keene DR, Hurlin PJ, Sequential and coordinated actions of c-Myc and N-Myc control appendicular skeletal development. PLoS One. 2011;6(4):e18795 |
Ptch2 patched 2 (Synonyms: ptc2) | |
Results | Reference |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:260962 Kamiunten T, Ideno H, Shimada A, Arai Y, Terashima T, Tomooka Y, Nakamura Y, Nakashima K, Kimura H, Shinkai Y, Tachibana M, Nifuji A, Essential roles of G9a in cell proliferation and differentiation during tooth development. Exp Cell Res. 2017 Aug 15;357(2):202-210 |
1 | J:151258 Kolterud A, Grosse AS, Zacharias WJ, Walton KD, Kretovich KE, Madison BB, Waghray M, Ferris JE, Hu C, Merchant JL, Dlugosz AA, Kottmann AH, Gumucio DL, Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning. Gastroenterology. 2009 Aug;137(2):618-28 |
1 | J:112118 Lee Y, Miller HL, Russell HR, Boyd K, Curran T, McKinnon PJ, Patched2 modulates tumorigenesis in patched1 heterozygous mice. Cancer Res. 2006 Jul 15;66(14):6964-71 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1* | J:319559 Wang X, Ma Z, Wu Y, Chen J, Peng X, Wang Y, Fan M, Du J, Expression pattern of Ptch2 in mouse embryonic maxillofacial development. Acta Histochem. 2022 Jan;124(1):151835 |
1 | J:116953 Yamago G, Takata Y, Furuta I, Urase K, Momoi T, Huh N, Suppression of hair follicle development inhibits induction of sonic hedgehog, patched, and patched-2 in hair germs in mice. Arch Dermatol Res. 2001 Sep;293(9):435-41 |
Ptcra pre T cell antigen receptor alpha (Synonyms: pT[a], pT-alpha, pTalpha) | |
Results | Reference |
1* | J:63747 Zuklys S, Balciunaite G, Agarwal A, Fasler-Kan E, Palmer E, Hollander GA, Normal thymic architecture and negative selection are associated with Aire expression, the gene defective in the autoimmune-polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED). J Immunol. 2000 Aug 15;165(4):1976-83 |
Pten phosphatase and tensin homolog (Synonyms: 2310035O07Rik, A130070J02Rik, B430203M17Rik, MMAC1, TEP1) | |
Results | Reference |
1 | J:154797 Cho KW, Cai J, Kim HY, Hosoya A, Ohshima H, Choi KY, Jung HS, ERK activation is involved in tooth development via FGF10 signaling. J Exp Zool B Mol Dev Evol. 2009 Dec 15;312(8):901-11 |
1* | J:131397 Cho KW, Cho SW, Lee JM, Lee MJ, Gang HS, Jung HS, Expression of phosphorylated forms of ERK, MEK, PTEN and PI3K in mouse oral development. Gene Expr Patterns. 2008 Apr;8(4):284-290 |
2 | J:166789 Dong Y, Sui L, Yamaguchi F, Kamitori K, Hirata Y, Hossain MA, Suzuki A, Holley MC, Tokuda M, Phosphatase and tensin homolog deleted on chromosome 10 regulates sensory cell proliferation and differentiation of hair bundles in the mammalian cochlea. Neuroscience. 2010 Nov 10;170(4):1304-13 |
1 | J:190411 Dong Y, Zhang L, Zhang S, Bai Y, Chen H, Sun X, Yong W, Li W, Colvin SC, Rhodes SJ, Shou W, Zhang ZY, Phosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) and activating Akt protein. J Biol Chem. 2012 Sep 14;287(38):32172-9 |
1 | J:197212 Kim HJ, Woo HM, Ryu J, Bok J, Kim JW, Choi SB, Park MH, Park HY, Koo SK, Conditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development. PLoS One. 2013;8(2):e55609 |
1 | J:312817 Lei X, Jiao J, UTX Affects Neural Stem Cell Proliferation and Differentiation through PTEN Signaling. Stem Cell Reports. 2018 Apr 10;10(4):1193-1207 |
1 | J:306158 Wang J, Cui Y, Yu Z, Wang W, Cheng X, Ji W, Guo S, Zhou Q, Wu N, Chen Y, Chen Y, Song X, Jiang H, Wang Y, Lan Y, Zhou B, Mao L, Li J, Yang H, Guo W, Yang X, Brain Endothelial Cells Maintain Lactate Homeostasis and Control Adult Hippocampal Neurogenesis. Cell Stem Cell. 2019 Dec 5;25(6):754-767.e9 |
1 | J:305176 Wei Y, Han X, Zhao C, PDK1 regulates the survival of the developing cortical interneurons. Mol Brain. 2020 May 4;13(1):65 |
Ptf1a pancreas specific transcription factor, 1a (Synonyms: bHLHa29, PTF1-p48) | |
Results | Reference |
1* | J:197142 Chang JC, Meredith DM, Mayer PR, Borromeo MD, Lai HC, Ou YH, Johnson JE, Prdm13 mediates the balance of inhibitory and excitatory neurons in somatosensory circuits. Dev Cell. 2013 Apr 29;25(2):182-95 |
1 | J:337474 Cobo I, Paliwal S, Bodas C, Felipe I, Melia-Aloma J, Torres A, Martinez-Villarreal J, Malumbres M, Garcia F, Millan I, Del Pozo N, Park JC, MacDonald RJ, Munoz J, Mendez R, Real FX, NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation. Nat Commun. 2023 Jun 23;14(1):3761 |
1 | J:304642 Dupacova N, Antosova B, Paces J, Kozmik Z, Meis homeobox genes control progenitor competence in the retina. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2013136118 |
1 | J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489 |
1 | J:115271 Fujitani Y, Fujitani S, Luo H, Qiu F, Burlison J, Long Q, Kawaguchi Y, Edlund H, Macdonald RJ, Furukawa T, Fujikado T, Magnuson MA, Xiang M, Wright CV, Ptf1a determines horizontal and amacrine cell fates during mouse retinal development. Development. 2006 Nov;133(22):4439-50 |
1 | J:268511 Fujiyama T, Miyashita S, Tsuneoka Y, Kanemaru K, Kakizaki M, Kanno S, Ishikawa Y, Yamashita M, Owa T, Nagaoka M, Kawaguchi Y, Yanagawa Y, Magnuson MA, Muratani M, Shibuya A, Nabeshima YI, Yanagisawa M, Funato H, Hoshino M, Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain. Cell Rep. 2018 Jul 3;24(1):79-94 |
1 | J:192856 George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE, Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol. 2012 Dec;32(24):5116-28 |
1 | J:100997 Hoshino M, Nakamura S, Mori K, Kawauchi T, Terao M, Nishimura YV, Fukuda A, Fuse T, Matsuo N, Sone M, Watanabe M, Bito H, Terashima T, Wright CV, Kawaguchi Y, Nakao K, Nabeshima Y, Ptf1a, a bHLH transcriptional gene, defines GABAergic neuronal fates in cerebellum. Neuron. 2005 Jul 21;47(2):201-13 |
1 | J:160335 Huang X, Liu J, Ketova T, Fleming JT, Grover VK, Cooper MK, Litingtung Y, Chiang C, Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8422-7 |
1 | J:222438 Klimova L, Antosova B, Kuzelova A, Strnad H, Kozmik Z, Onecut1 and Onecut2 transcription factors operate downstream of Pax6 to regulate horizontal cell development. Dev Biol. 2015 Jun 1;402(1):48-60 |
1 | J:125691 Masui T, Long Q, Beres TM, Magnuson MA, Macdonald RJ, Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex. Genes Dev. 2007 Oct 15;21(20):2629-43 |
1 | J:119184 Nakhai H, Sel S, Favor J, Mendoza-Torres L, Paulsen F, Duncker GI, Schmid RM, Ptf1a is essential for the differentiation of GABAergic and glycinergic amacrine cells and horizontal cells in the mouse retina. Development. 2007 Mar;134(6):1151-60 |
1 | J:191071 Petzold KM, Naumann H, Spagnoli FM, Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas. Development. 2013 Jan 1;140(1):126-35 |
1 | J:130904 Poche RA, Kwan KM, Raven MA, Furuta Y, Reese BE, Behringer RR, Lim1 is essential for the correct laminar positioning of retinal horizontal cells. J Neurosci. 2007 Dec 19;27(51):14099-107 |
1 | J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356 |
1 | J:147764 Svensson P, Bergqvist I, Norlin S, Edlund H, MFng is dispensable for mouse pancreas development and function. Mol Cell Biol. 2009 Apr;29(8):2129-38 |
1 | J:354849 Wutikeli H, Yu Y, Zhang T, Cao J, Nawy S, Shen Y, Role of Elavl-like RNA-binding protein in retinal development and signal transduction. Biochim Biophys Acta Mol Basis Dis. 2024 Sep 20;1871(1):167518 |
1 | J:210443 Yamada M, Seto Y, Taya S, Owa T, Inoue YU, Inoue T, Kawaguchi Y, Nabeshima Y, Hoshino M, Specification of spatial identities of cerebellar neuron progenitors by ptf1a and atoh1 for proper production of GABAergic and glutamatergic neurons. J Neurosci. 2014 Apr 2;34(14):4786-800 |
1 | J:309104 Zheng MH, Shi M, Pei Z, Gao F, Han H, Ding YQ, The transcription factor RBP-J is essential for retinal cell differentiation and lamination. Mol Brain. 2009 Dec 18;2:38 |
Ptgds prostaglandin D2 synthase (brain) (Synonyms: L-PGDS, PGD2, Ptgs3) | |
Results | Reference |
1 | J:36585 Hoffmann A, Bachner D, Betat N, Lauber J, Gross G, Developmental expression of murine Beta-trace in embryos and adult animals suggests a function in maturation and maintenance of blood-tissue barriers. Dev Dyn. 1996 Nov;207(3):332-43 |
1* | J:48079 Kume T, Deng KY, Winfrey V, Gould DB, Walter MA, Hogan BL, The forkhead/winged helix gene Mf1 is disrupted in the pleiotropic mouse mutation congenital hydrocephalus. Cell. 1998 Jun 12;93(6):985-96 |
1 | J:246806 Li Y, Zhang L, Hu Y, Chen M, Han F, Qin Y, Chen M, Cui X, Duo S, Tang F, Gao F, beta-Catenin directs the transformation of testis Sertoli cells to ovarian granulosa-like cells by inducing Foxl2 expression. J Biol Chem. 2017 Oct 27;292(43):17577-17586 |
1* | J:114661 Lyu YL, Lin CP, Azarova AM, Cai L, Wang JC, Liu LF, Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Mol Cell Biol. 2006 Nov;26(21):7929-41 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Ptger3 prostaglandin E receptor 3 (subtype EP3) (Synonyms: EP3, Pgerep3, Ptgerep3) | |
Results | Reference |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
Ptger4 prostaglandin E receptor 4 (subtype EP4) (Synonyms: EP4, Ptgerep4) | |
Results | Reference |
1 | J:219318 Yokoyama U, Minamisawa S, Shioda A, Ishiwata R, Jin MH, Masuda M, Asou T, Sugimoto Y, Aoki H, Nakamura T, Ishikawa Y, Prostaglandin E2 inhibits elastogenesis in the ductus arteriosus via EP4 signaling. Circulation. 2014 Jan 28;129(4):487-96 |
Ptgs1 prostaglandin-endoperoxide synthase 1 (Synonyms: Cox-1, COX1, Cox-3, cyclooxygenase 1, Pghs1) | |
Results | Reference |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Ptgs2 prostaglandin-endoperoxide synthase 2 (Synonyms: Cox-2, COX2, cyclooxygenase 2, cyclooxygenase-2, Pghs2, PGHS-2, PHS-2, prostaglandin G/H synthase, Tis10) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47 |
1 | J:185829 Park CB, DeMayo FJ, Lydon JP, Dufort D, NODAL in the uterus is necessary for proper placental development and maintenance of pregnancy. Biol Reprod. 2012 Jun;86(6):194 |
1 | J:331834 Zhang F, Sun K, Wang WS, Identification of a Feed-Forward Loop Between 15(S)-HETE and PGE2 in Human Amnion at Parturition. J Lipid Res. 2022 Oct 4;63(11):100294 |
Pth parathyroid hormone | |
Results | Reference |
1 | J:316647 Kameda Y, Saitoh T, Nemoto N, Katoh T, Iseki S, Fujimura T, Hes1 is required for the development of pharyngeal organs and survival of neural crest-derived mesenchymal cells in pharyngeal arches. Cell Tissue Res. 2013 Jul;353(1):9-25 |
1* | J:50339 Kim J, Jones BW, Zock C, Chen Z, Wang H, Goodman CS, Anderson DJ, Isolation and characterization of mammalian homologs of the Drosophila gene glial cells missing. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12364-9 |
1* | J:167511 Liu Z, Farley A, Chen L, Kirby BJ, Kovacs CS, Blackburn CC, Manley NR, Thymus-associated parathyroid hormone has two cellular origins with distinct endocrine and immunological functions. PLoS Genet. 2010;6(12):e1001251 |
Pth1r parathyroid hormone 1 receptor (Synonyms: PPR, PTH1R, PTH/PTHrP receptor, Pthr1, PTH-related peptide receptor) | |
Results | Reference |
1 | J:90567 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 2004 May 1;18(9):1072-87 |
1* | J:75699 Albrecht AN, Schwabe GC, Stricker S, Boddrich A, Wanker EE, Mundlos S, The synpolydactyly homolog (spdh) mutation in the mouse -- a defect in patterning and growth of limb cartilage elements. Mech Dev. 2002 Mar;112(1-2):53-67 |
1 | J:346119 Amano K, Okuzaki D, Kitaoka Y, Kato S, Fujiwara M, Tanaka S, Iida S, Pth1r in Neural Crest Cells Regulates Nasal Cartilage Differentiation. J Dent Res. 2024 Mar;103(3):308-317 |
1 | J:155396 Bellon E, Luyten FP, Tylzanowski P, delta-EF1 is a negative regulator of Ihh in the developing growth plate. J Cell Biol. 2009 Nov 30;187(5):685-99 |
1* | J:168038 Bimonte S, De Angelis A, Quagliata L, Giusti F, Tammaro R, Dallai R, Ascenzi MG, Diez-Roux G, Franco B, Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol. 2011 Jan 15;349(2):179-91 |
1 | J:156015 Blitz E, Viukov S, Sharir A, Shwartz Y, Galloway JL, Pryce BA, Johnson RL, Tabin CJ, Schweitzer R, Zelzer E, Bone ridge patterning during musculoskeletal assembly is mediated through SCX regulation of Bmp4 at the tendon-skeleton junction. Dev Cell. 2009 Dec;17(6):861-73 |
1* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1* | J:66902 Colnot C, Sidhu SS, Balmain N, Poirier F, Uncoupling of chondrocyte death and vascular invasion in mouse galectin 3 null mutant bones. Dev Biol. 2001 Jan 1;229(1):203-14 |
1 | J:111426 Ganss B, Kobayashi H, The zinc finger transcription factor Zfp60 is a negative regulator of cartilage differentiation. J Bone Miner Res. 2002 Dec;17(12):2151-60 |
1 | J:150187 Guo X, Mak KK, Taketo MM, Yang Y, The Wnt/beta-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturation. PLoS One. 2009;4(6):e6067 |
1* | J:194983 Ideno H, Shimada A, Imaizumi K, Kimura H, Abe M, Nakashima K, Nifuji A, Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development. Gene Expr Patterns. 2013 Mar-Apr;13(3-4):84-90 |
1 | J:119288 Jacob AL, Smith C, Partanen J, Ornitz DM, Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation. Dev Biol. 2006 Aug 15;296(2):315-28 |
1 | J:102948 Koziel L, Wuelling M, Schneider S, Vortkamp A, Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation. Development. 2005 Dec;132(23):5249-60 |
2* | J:60156 Lee K, Lanske B, Karaplis AC, Deeds JD, Kohno H, Nissenson RA, Kronenberg HM, Segre GV, Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development. Endocrinology. 1996 Nov;137(11):5109-18 |
1 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
1 | J:125095 Lu J, Lian G, Lenkinski R, De Grand A, Vaid RR, Bryce T, Stasenko M, Boskey A, Walsh C, Sheen V, Filamin B mutations cause chondrocyte defects in skeletal development. Hum Mol Genet. 2007 Jul 15;16(14):1661-75 |
1 | J:100378 MacLean HE, Kronenberg HM, Localization of Indian hedgehog and PTH/PTHrP receptor expression in relation to chondrocyte proliferation during mouse bone development. Dev Growth Differ. 2005 Feb;47(2):59-63 |
1 | J:193853 Makino Y, Takahashi Y, Tanabe R, Tamamura Y, Watanabe T, Haraikawa M, Hamagaki M, Hata K, Kanno J, Yoneda T, Saga Y, Goseki-Sone M, Kaneko K, Yamaguchi A, Iimura T, Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone. 2013 Mar;53(1):248-58 |
1 | J:296737 Matsuura VKSK, Yoshida CA, Komori H, Sakane C, Yamana K, Jiang Q, Komori T, Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice. Int J Mol Sci. 2020 Apr 12;21(8):2682 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1* | J:199462 Probst S, Zeller R, Zuniga A, The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development. Differentiation. 2013 Apr-Jun;85(4-5):121-30 |
1 | J:147287 Retting KN, Song B, Yoon BS, Lyons KM, BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation. Development. 2009 Apr;136(7):1093-104 |
1 | J:76480 Robledo RF, Rajan L, Li X, Lufkin T, The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev. 2002 May 1;16(9):1089-101 |
1 | J:124105 Ruiz-Perez VL, Blair HJ, Rodriguez-Andres ME, Blanco MJ, Wilson A, Liu YN, Miles C, Peters H, Goodship JA, Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. Development. 2007 Aug;134(16):2903-12 |
1 | J:187998 Shung CY, Ota S, Zhou ZQ, Keene DR, Hurlin PJ, Disruption of a Sox9-beta-catenin circuit by mutant Fgfr3 in thanatophoric dysplasia type II. Hum Mol Genet. 2012 Nov 1;21(21):4628-44 |
1 | J:88817 Smits P, Dy P, Mitra S, Lefebvre V, Sox5 and Sox6 are needed to develop and maintain source, columnar, and hypertrophic chondrocytes in the cartilage growth plate. J Cell Biol. 2004 Mar 1;164(5):747-58 |
1* | J:80666 Smits P, Li P, Mandel J, Zhang Z, Deng JM, Behringer RR, de Croumbrugghe B, Lefebvre V, The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001 Aug;1(2):277-90 |
1* | J:76742 Vortkamp A, Lee K, Lanske B, Segre GV, Kronenberg HM, Tabin CJ, Regulation of rate of cartilage differentiation by Indian hedgehog and PTH-related protein. Science. 1996 Aug 2;273(5275):613-22 |
1* | J:154906 Wang W, Lian N, Li L, Moss HE, Wang W, Perrien DS, Elefteriou F, Yang X, Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating Ihh transcription. Development. 2009 Dec;136(24):4143-53 |
1 | J:172737 Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RA, Peterson AS, Solloway MJ, Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol. 2011 May 30;193(5):935-51 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1 | J:60102 Yamazaki K, Suda N, Kuroda T, Distribution of parathyroid hormone-related protein (PTHrP) and type I parathyroid hormone (PTH) PTHrP receptor in developing mouse mandibular condylar cartilage. Arch Oral Biol. 1999 Oct;44(10):853-60 |
1 | J:172282 Zhou ZQ, Shung CY, Ota S, Akiyama H, Keene DR, Hurlin PJ, Sequential and coordinated actions of c-Myc and N-Myc control appendicular skeletal development. PLoS One. 2011;6(4):e18795 |
Pthlh parathyroid hormone-like peptide (Synonyms: parathyroid hormone-like hormone, parathyroid hormone-related peptide, parathyroid hormone-related protein, PTH-like, PTH-related peptide, Pthrp) | |
Results | Reference |
1 | J:90567 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 2004 May 1;18(9):1072-87 |
1 | J:155396 Bellon E, Luyten FP, Tylzanowski P, delta-EF1 is a negative regulator of Ihh in the developing growth plate. J Cell Biol. 2009 Nov 30;187(5):685-99 |
1* | J:168038 Bimonte S, De Angelis A, Quagliata L, Giusti F, Tammaro R, Dallai R, Ascenzi MG, Diez-Roux G, Franco B, Ofd1 is required in limb bud patterning and endochondral bone development. Dev Biol. 2011 Jan 15;349(2):179-91 |
1 | J:188176 Caparros-Martin JA, Valencia M, Reytor E, Pacheco M, Fernandez M, Perez-Aytes A, Gean E, Lapunzina P, Peters H, Goodship JA, Ruiz-Perez VL, The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia. Hum Mol Genet. 2013 Jan 1;22(1):124-39 |
1* | J:128121 Chen X, Macica CM, Dreyer BE, Hammond VE, Hens JR, Philbrick WM, Broadus AE, Initial characterization of PTH-related protein gene-driven lacZ expression in the mouse. J Bone Miner Res. 2006 Jan;21(1):113-23 |
1 | J:102948 Koziel L, Wuelling M, Schneider S, Vortkamp A, Gli3 acts as a repressor downstream of Ihh in regulating two distinct steps of chondrocyte differentiation. Development. 2005 Dec;132(23):5249-60 |
1* | J:60156 Lee K, Lanske B, Karaplis AC, Deeds JD, Kohno H, Nissenson RA, Kronenberg HM, Segre GV, Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development. Endocrinology. 1996 Nov;137(11):5109-18 |
1 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1 | J:147287 Retting KN, Song B, Yoon BS, Lyons KM, BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation. Development. 2009 Apr;136(7):1093-104 |
1 | J:124105 Ruiz-Perez VL, Blair HJ, Rodriguez-Andres ME, Blanco MJ, Wilson A, Liu YN, Miles C, Peters H, Goodship JA, Evc is a positive mediator of Ihh-regulated bone growth that localises at the base of chondrocyte cilia. Development. 2007 Aug;134(16):2903-12 |
1 | J:340421 Ruscitto A, Chen P, Tosa I, Wang Z, Zhou G, Safina I, Wei R, Morel MM, Koch A, Forman M, Reeve G, Lecholop MK, Wilson M, Bonthius D, Chen M, Ono M, Wang TC, Yao H, Embree MC, Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity. Cell Stem Cell. 2023 Sep 7;30(9):1179-1198.e7 |
1* | J:80666 Smits P, Li P, Mandel J, Zhang Z, Deng JM, Behringer RR, de Croumbrugghe B, Lefebvre V, The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001 Aug;1(2):277-90 |
1 | J:134924 Spagnoli A, O'Rear L, Chandler RL, Granero-Molto F, Mortlock DP, Gorska AE, Weis JA, Longobardi L, Chytil A, Shimer K, Moses HL, TGF-beta signaling is essential for joint morphogenesis. J Cell Biol. 2007 Jun 18;177(6):1105-17 |
1 | J:112002 van der Weyden L, Wei L, Luo J, Yang X, Birk DE, Adams DJ, Bradley A, Chen Q, Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis. Am J Pathol. 2006 Aug;169(2):515-27 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1 | J:149459 Wuelling M, Kaiser FJ, Buelens LA, Braunholz D, Shivdasani RA, Depping R, Vortkamp A, Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. Dev Biol. 2009 Apr 1;328(1):40-53 |
1 | J:45347 Yamazaki K, Suda N, Kuroda T, Immunohistochemical localization of parathyroid hormone-related protein in developing mouse Meckel's cartilage and mandible. Arch Oral Biol. 1997 Dec;42(12):787-94 |
1 | J:60102 Yamazaki K, Suda N, Kuroda T, Distribution of parathyroid hormone-related protein (PTHrP) and type I parathyroid hormone (PTH) PTHrP receptor in developing mouse mandibular condylar cartilage. Arch Oral Biol. 1999 Oct;44(10):853-60 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
Ptk2 PTK2 protein tyrosine kinase 2 (Synonyms: Fadk, FAK, FRNK) | |
Results | Reference |
1 | J:331894 Alcantara MC, Suzuki K, Acebedo AR, Kajioka D, Hirohata S, Kaisho T, Hatano Y, Yamagata K, Takahashi S, Yamada G, Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice. iScience. 2022 Dec 22;25(12):105609 |
1* | J:164222 Beverdam A, Svingen T, Bagheri-Fam S, McClive P, Sinclair AH, Harley VR, Koopman P, Protein tyrosine kinase 2 beta (PTK2B), but not focal adhesion kinase (FAK), is expressed in a sexually dimorphic pattern in developing mouse gonads. Dev Dyn. 2010 Oct;239(10):2735-41 |
1* | J:316187 Chacon MR, Navarro AI, Cuesto G, del Pino I, Scott R, Morales M, Rico B, Focal adhesion kinase regulates actin nucleation and neuronal filopodia formation during axonal growth. Development. 2012 Sep;139(17):3200-10 |
1 | J:175562 Cho IH, Lee KW, Ha HY, Han PL, JNK/stress-activated protein kinase associated protein 1 is required for early development of telencephalic commissures in embryonic brains. Exp Mol Med. 2011 Aug 31;43(8):462-70 |
1 | J:101055 Kuo G, Arnaud L, Kronstad-O'Brien P, Cooper JA, Absence of Fyn and Src causes a reeler-like phenotype. J Neurosci. 2005 Sep 14;25(37):8578-86 |
1* | J:316578 Lade A, Ranganathan S, Luo J, Monga SP, Calpain induces N-terminal truncation of beta-catenin in normal murine liver development: diagnostic implications in hepatoblastomas. J Biol Chem. 2012 Jun 29;287(27):22789-98 |
1 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
1* | J:85235 Xie Z, Sanada K, Samuels BA, Shih H, Tsai LH, Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration. Cell. 2003 Aug 22;114(4):469-82 |
Ptk2b PTK2 protein tyrosine kinase 2 beta (Synonyms: CAKbeta, calcium-dependent tyrosine kinase, cellular adhesion kinase beta, E430023O05Rik, proline-rich tyrosine kinase 2, PYK2, Raftk, related adhesion focal tyrosine kinase) | |
Results | Reference |
1* | J:164222 Beverdam A, Svingen T, Bagheri-Fam S, McClive P, Sinclair AH, Harley VR, Koopman P, Protein tyrosine kinase 2 beta (PTK2B), but not focal adhesion kinase (FAK), is expressed in a sexually dimorphic pattern in developing mouse gonads. Dev Dyn. 2010 Oct;239(10):2735-41 |
Ptk6 PTK6 protein tyrosine kinase 6 (Synonyms: Sik, Tksk) | |
Results | Reference |
1* | J:22508 Vasioukhin V, Serfas MS, Siyanova EY, Polonskaia M, Costigan VJ, Liu B, Thomason A, Tyner AL, A novel intracellular epithelial cell tyrosine kinase is expressed in the skin and gastrointestinal tract. Oncogene. 1995 Jan 19;10(2):349-57 |
Ptk7 PTK7 protein tyrosine kinase 7 (Synonyms: 8430404F20Rik, chz, mPTK7/CCK4) | |
Results | Reference |
1* | J:88984 Jung JW, Shin WS, Song J, Lee ST, Cloning and characterization of the full-length mouse Ptk7 cDNA encoding a defective receptor protein tyrosine kinase. Gene. 2004 Mar 17;328:75-84 |
1 | J:273200 Landin Malt A, Dailey Z, Holbrook-Rasmussen J, Zheng Y, Hogan A, Du Q, Lu X, Par3 is essential for the establishment of planar cell polarity of inner ear hair cells. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4999-5008 |
1 | J:199510 Lee J, Andreeva A, Sipe CW, Liu L, Cheng A, Lu X, PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium. Curr Biol. 2012 Jun 5;22(11):956-66 |
2 | J:91298 Lu X, Borchers AG, Jolicoeur C, Rayburn H, Baker JC, Tessier-Lavigne M, PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates. Nature. 2004 Jul 1;430(6995):93-8 |
Ptma prothymosin alpha (Synonyms: Thym) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:32154 Moll J, Schmid P, Sansig G, van der Putten H, The pattern of prothymosin alpha gene expression coincides with that of myc proto-oncogenes during mouse embryogenesis. Histochem J. 1996 Jan;28(1):45-52 |
Ptn pleiotrophin (Synonyms: HB-GAM, HBGF-8, HBNF, heparin-binding growth-associated molecule, heparin-binding growth factor 8, Osf-1, Osf1) | |
Results | Reference |
1* | J:276701 Cui R, Lwigale P, Expression of the heparin-binding growth factors Midkine and pleiotrophin during ocular development. Gene Expr Patterns. 2019 Jun;32:28-37 |
1 | J:139147 Mitsiadis TA, Caton J, De Bari C, Bluteau G, The large functional spectrum of the heparin-binding cytokines MK and HB-GAM in continuously growing organs: the rodent incisor as a model. Dev Biol. 2008 Aug 1;320(1):256-66 |
1* | J:22554 Mitsiadis TA, Salmivirta M, Muramatsu T, Muramatsu H, Rauvala H, Lehtonen E, Jalkanen M, Thesleff I, Expression of the heparin-binding cytokines, midkine (MK) and HB-GAM (pleiotrophin) is associated with epithelial-mesenchymal interactions during fetal development and organogenesis. Development. 1995 Jan;121(1):37-51 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
1* | J:157199 Yanagisawa H, Komuta Y, Kawano H, Toyoda M, Sango K, Pleiotrophin induces neurite outgrowth and up-regulates growth-associated protein (GAP)-43 mRNA through the ALK/GSK3beta/beta-catenin signaling in developing mouse neurons. Neurosci Res. 2010 Jan;66(1):111-6 |
Ptp4a2 protein tyrosine phosphatase 4a2 (Synonyms: Prl-2) | |
Results | Reference |
1 | J:190411 Dong Y, Zhang L, Zhang S, Bai Y, Chen H, Sun X, Yong W, Li W, Colvin SC, Rhodes SJ, Shou W, Zhang ZY, Phosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) and activating Akt protein. J Biol Chem. 2012 Sep 14;287(38):32172-9 |
Ptpn6 protein tyrosine phosphatase, non-receptor type 6 (Synonyms: hcp, Hcph, Ptp1C, SHP-1, Spin) | |
Results | Reference |
1* | J:317552 Casey SC, Blumberg B, The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver. Mol Endocrinol. 2012 Jun;26(6):916-25 |
Ptpn11 protein tyrosine phosphatase, non-receptor type 11 (Synonyms: 2700084A17Rik, PTP1D, PTP2C, SH2 domain-containing protein tyrosine phosphatase-2, Shp2, SHP-2, SH-PTP2, Syp) | |
Results | Reference |
1* | J:19469 Feng GS, Hui CC, Pawson T, SH2-containing phosphotyrosine phosphatase as a target of protein-tyrosine kinases. Science. 1993 Mar 12;259(5101):1607-11 |
2 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:124878 Sierro F, Biben C, Martinez-Munoz L, Mellado M, Ransohoff RM, Li M, Woehl B, Leung H, Groom J, Batten M, Harvey RP, Martinez-A C, Mackay CR, Mackay F, Disrupted cardiac development but normal hematopoiesis in mice deficient in the second CXCL12/SDF-1 receptor, CXCR7. Proc Natl Acad Sci U S A. 2007 Sep 11;104(37):14759-64 |
Ptpn12 protein tyrosine phosphatase, non-receptor type 12 (Synonyms: P19-PTP, PTP-P19, PTP-PEST) | |
Results | Reference |
1* | J:24425 Charest A, Wagner J, Shen SH, Tremblay ML, Murine protein tyrosine phosphatase-PEST, a stable cytosolic protein tyrosine phosphatase. Biochem J. 1995 Jun 1;308(Pt 2):425-32 |
Ptpn13 protein tyrosine phosphatase, non-receptor type 13 (Synonyms: PTP-BL, PTPL1, Ptpri) | |
Results | Reference |
1* | J:31214 Hendriks W, Schepens J, Bachner D, Rijss J, Zeeuwen P, Zechner U, Hameister H, Wieringa B, Molecular cloning of a mouse epithelial protein-tyrosine phosphatase with similarities to submembranous proteins. J Cell Biochem. 1995 Dec;59(4):418-30 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Ptpn23 protein tyrosine phosphatase, non-receptor type 23 (Synonyms: PTP-TD14) | |
Results | Reference |
1* | J:153790 Gingras MC, Kharitidi D, Chenard V, Uetani N, Bouchard M, Tremblay ML, Pause A, Expression analysis and essential role of the putative tyrosine phosphatase His-domain-containing protein tyrosine phosphatase (HD-PTP). Int J Dev Biol. 2009;53(7):1069-74 |
Ptprb protein tyrosine phosphatase receptor type B (Synonyms: 3230402H02Rik, VE-PTP) | |
Results | Reference |
1 | J:247344 Takahashi K, Kim R, Lauhan C, Park Y, Nguyen NG, Vestweber D, Dominguez MG, Valenzuela DM, Murphy AJ, Yancopoulos GD, Gale NW, Takahashi T, Expression of receptor-type protein tyrosine phosphatase in developing and adult renal vasculature. PLoS One. 2017;12(5):e0177192 |
Ptprc protein tyrosine phosphatase receptor type C (Synonyms: B220, CD45, Ly-5, Lyt-4, T200) | |
Results | Reference |
1 | J:186083 Calderon L, Boehm T, Synergistic, context-dependent, and hierarchical functions of epithelial components in thymic microenvironments. Cell. 2012 Mar 30;149(1):159-72 |
1* | J:313926 Cichon MA, Klas K, Buchberger M, Hammer M, Sere K, Zenke M, Tschachler E, Elbe-Burger A, Distinct Distribution of RTN1A in Immune Cells in Mouse Skin and Lymphoid Organs. Front Cell Dev Biol. 2020;8:608876 |
1 | J:360776 Di Michele M, Attina A, Roux PF, Tabet I, Laguesse S, Florido J, Houdeville M, Choquet A, Encislai B, Arena G, De Blasio C, Wendling O, Frenois FX, Papon L, Stuani L, Fuentes M, Jahannault Talignani C, Rousseau M, Guegan J, Buscail Y, Dupre P, Michaud HA, Rodier G, Bellvert F, Kulyk H, Ferraro Peyret C, Mathieu H, Close P, Rapino F, Chaveroux C, Pirot N, Rubio L, Torro A, Sorg T, Ango F, Hirtz C, Compan V, Lebigot E, Legati A, Ghezzi D, Nguyen L, David A, Sardet C, Lacroix M, Le Cam L, E4F1 coordinates pyruvate metabolism and the activity of the elongator complex to ensure translation fidelity during brain development. Nat Commun. 2025 Jan 2;16(1):67 |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1 | J:87395 Eberl G, Marmon S, Sunshine MJ, Rennert PD, Choi Y, Littman DR, An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat Immunol. 2004 Jan;5(1):64-73 |
1 | J:173280 Goossens S, Janzen V, Bartunkova S, Yokomizo T, Drogat B, Crisan M, Haigh K, Seuntjens E, Umans L, Riedt T, Bogaert P, Haenebalcke L, Berx G, Dzierzak E, Huylebroeck D, Haigh JJ, The EMT regulator Zeb2/Sip1 is essential for murine embryonic hematopoietic stem/progenitor cell differentiation and mobilization. Blood. 2011 May 26;117(21):5620-30 |
1 | J:334094 Gu X, Heinrich A, Li SY, DeFalco T, Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions. Nat Commun. 2023 Mar 15;14(1):1439 |
1 | J:291487 Liu D, Kousa AI, O'Neill KE, Rouse P, Popis M, Farley AM, Tomlinson SR, Ulyanchenko S, Guillemot F, Seymour PA, Jorgensen MC, Serup P, Koch U, Radtke F, Blackburn CC, Canonical Notch signaling controls the early thymic epithelial progenitor cell state and emergence of the medullary epithelial lineage in fetal thymus development. Development. 2020 Jun 22;147(12):dev178582 |
1 | J:339241 Liu, K., Intercellular genetic tracing of cardiac endothelium in the developing heart. Dev Cell. 2023 Aug 21;58(16):1502-1512 |
1* | J:71183 Su D, Ellis S, Napier A, Lee K, Manley NR, Hoxa3 and pax1 regulate epithelial cell death and proliferation during thymus and parathyroid organogenesis. Dev Biol. 2001 Aug 15;236(2):316-29 |
1 | J:336858 Vallecillo-Garcia P, Orgeur M, Comai G, Poehle-Kronnawitter S, Fischer C, Gloger M, Dumas CE, Giesecke-Thiel C, Sauer S, Tajbakhsh S, Hopken UE, Stricker S, A local subset of mesenchymal cells expressing the transcription factor Osr1 orchestrates lymph node initiation. Immunity. 2023 Jun 13;56(6):1204-1219.e8 |
1 | J:137812 Vondenhoff MF, Desanti GE, Cupedo T, Bertrand JY, Cumano A, Kraal G, Mebius RE, Golub R, Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner. J Leukoc Biol. 2008 Jul;84(1):152-61 |
1 | J:150308 Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009 May 1;182(9):5439-45 |
1 | J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34 |
1 | J:362739 Wu Y, Qin K, Xu Y, Rajhans S, Vo T, Lopez KM, Liu J, Nipper MH, Deng J, Yin X, Ramjit LR, Ye Z, Luan Y, Arda HE, Wang P, Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation. Elife. 2024 Jul 25;13 |
Ptprd protein tyrosine phosphatase receptor type D (Synonyms: 1110002J03Rik, 3000002J10Rik, B230219D21Rik, MGC:36851) | |
Results | Reference |
1 | J:346120 Cornejo F, Franchini N, Cortes BI, Elgueta D, Cancino GI, Neural conditional ablation of the protein tyrosine phosphatase receptor Delta PTPRD impairs gliogenesis in the developing mouse brain cortex. Front Cell Dev Biol. 2024;12:1357862 |
1 | J:21938 Mizuno K, Hasegawa K, Ogimoto M, Katagiri T, Yakura H, Developmental regulation of gene expression for the MPTP delta isoforms in the central nervous system and the immune system. FEBS Lett. 1994 Dec 5;355(3):223-8 |
1* | J:50941 Schaapveld RQ, Schepens JT, Bachner D, Attema J, Wieringa B, Jap PH, Hendriks WJ, Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse. Mech Dev. 1998 Sep;77(1):59-62 |
Ptprf protein tyrosine phosphatase receptor type F (Synonyms: LAR, RPTP-LAR) | |
Results | Reference |
1* | J:50941 Schaapveld RQ, Schepens JT, Bachner D, Attema J, Wieringa B, Jap PH, Hendriks WJ, Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse. Mech Dev. 1998 Sep;77(1):59-62 |
Ptprg protein tyrosine phosphatase receptor type G (Synonyms: 5430405N12Rik, RPTPgamma) | |
Results | Reference |
1* | J:68840 Nakagawa Y, O'Leary DD, Combinatorial expression patterns of LIM-homeodomain and other regulatory genes parcellate developing thalamus. J Neurosci. 2001 Apr 15;21(8):2711-25 |
Ptprh protein tyrosine phosphatase receptor type H (Synonyms: SAP-1) | |
Results | Reference |
2* | J:146871 Sadakata H, Okazawa H, Sato T, Supriatna Y, Ohnishi H, Kusakari S, Murata Y, Ito T, Nishiyama U, Minegishi T, Harada A, Matozaki T, SAP-1 is a microvillus-specific protein tyrosine phosphatase that modulates intestinal tumorigenesis. Genes Cells. 2009 Mar;14(3):295-308 |
Ptprj protein tyrosine phosphatase receptor type J (Synonyms: Byp, CD148, DEP-1, RPTPJ, Scc-1, Scc1) | |
Results | Reference |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
Ptprk protein tyrosine phosphatase receptor type K (Synonyms: PTPk, RPTPkappa) | |
Results | Reference |
1* | J:46142 Fuchs M, Wang H, Ciossek T, Chen Z, Ullrich A, Differential expression of MAM-subfamily protein tyrosine phosphatases during mouse development. Mech Dev. 1998 Jan;70(1-2):91-109 |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Ptprm protein tyrosine phosphatase receptor type M (Synonyms: RPTPmu) | |
Results | Reference |
2 | J:238868 Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z, The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 2016 Aug 02;16(5):1431-44 |
Ptprs protein tyrosine phosphatase receptor type S (Synonyms: PTP-NU3, PTPsigma, Ptpt9, RPTPsigma) | |
Results | Reference |
1* | J:50941 Schaapveld RQ, Schepens JT, Bachner D, Attema J, Wieringa B, Jap PH, Hendriks WJ, Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse. Mech Dev. 1998 Sep;77(1):59-62 |
Ptpru protein tyrosine phosphatase receptor type U (Synonyms: Ptprl, RPTPlambda) | |
Results | Reference |
1* | J:46142 Fuchs M, Wang H, Ciossek T, Chen Z, Ullrich A, Differential expression of MAM-subfamily protein tyrosine phosphatases during mouse development. Mech Dev. 1998 Jan;70(1-2):91-109 |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Ptprv protein tyrosine phosphatase receptor type V (Synonyms: Esp, mOST-PTP, OST, OST-PTP) | |
Results | Reference |
2* | J:89221 Dacquin R, Mee PJ, Kawaguchi J, Olmsted-Davis EA, Gallagher JA, Nichols J, Lee K, Karsenty G, Smith A, Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar. Dev Dyn. 2004 Apr;229(4):826-34 |
Ptprz1 protein tyrosine phosphatase receptor type Z, polypeptide 1 (Synonyms: DSD-1-PG, phosphacan, PTPbeta, Ptprz, Ptpz, PTPzeta, Rptpbeta, RPTPz) | |
Results | Reference |
1* | J:63083 Clarris HJ, Rauch U, Key B, Dynamic spatiotemporal expression patterns of neurocan and phosphacan indicate diverse roles in the developing and adult mouse olfactory system. J Comp Neurol. 2000 Jul 17;423(1):99-111 |
1 | J:259186 Heng X, Guo Q, Leung AW, Li JY, Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6:e23253 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Pttg1 pituitary tumor-transforming gene 1 (Synonyms: PTTG, securin) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1 | J:340740 Xu J, Zhou X, Zhang T, Zhang B, Xu PX, Smarca4 deficiency induces Pttg1 oncogene upregulation and hyperproliferation of tubular and interstitial cells during kidney development. Front Cell Dev Biol. 2023;11:1233317 |
Pum1 pumilio RNA-binding family member 1 (Synonyms: mKIAA0099, Pumm) | |
Results | Reference |
1* | J:104317 Islam S, Montgomery RK, Fialkovich JJ, Grand RJ, Developmental and regional expression and localization of mRNAs encoding proteins involved in RNA translocation. J Histochem Cytochem. 2005 Dec;53(12):1501-9 |
Pum2 pumilio RNA-binding family member 2 (Synonyms: 5730503J23Rik, mKIAA0235, Pumm2) | |
Results | Reference |
1 | J:158581 Barrios F, Filipponi D, Pellegrini M, Paronetto MP, Di Siena S, Geremia R, Rossi P, De Felici M, Jannini EA, Dolci S, Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells. J Cell Sci. 2010 Mar 15;123(Pt 6):871-80 |
Pvalb parvalbumin (Synonyms: Parv, PV, Pva) | |
Results | Reference |
1 | J:78232 Arber S, Ladle DR, Lin JH, Frank E, Jessell TM, ETS gene Er81 controls the formation of functional connections between group Ia sensory afferents and motor neurons. Cell. 2000 May 26;101(5):485-98 |
1 | J:333392 Cao R, Chen P, Wang H, Jing H, Zhang H, Xing G, Luo B, Pan J, Yu Z, Xiong WC, Mei L, Intrafusal-fiber LRP4 for muscle spindle formation and maintenance in adult and aged animals. Nat Commun. 2023 Feb 10;14(1):744 |
1 | J:94263 Davila JC, Real MA, Olmos L, Legaz I, Medina L, Guirado S, Embryonic and postnatal development of GABA, calbindin, calretinin, and parvalbumin in the mouse claustral complex. J Comp Neurol. 2005 Jan 3;481(1):42-57 |
1 | J:126322 Gao X, Daugherty RL, Tourtellotte WG, Regulation of low affinity neurotrophin receptor (p75(NTR)) by early growth response (Egr) transcriptional regulators. Mol Cell Neurosci. 2007 Dec;36(4):501-14 |
1 | J:132854 Gould TW, Yonemura S, Oppenheim RW, Ohmori S, Enomoto H, The neurotrophic effects of glial cell line-derived neurotrophic factor on spinal motoneurons are restricted to fusimotor subtypes. J Neurosci. 2008 Feb 27;28(9):2131-46 |
1* | J:229257 Gu Z, Imai F, Kim IJ, Fujita H, Katayama Ki, Mori K, Yoshihara Y, Yoshida Y, Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. PLoS One. 2015;10(3):e0121550 |
1 | J:345844 Guo Y, Xiang P, Sun X, Liu W, Zhou J, Yin B, Hou L, Qiang B, Li H, Shu P, Peng X, Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy. Signal Transduct Target Ther. 2024 Feb 14;9(1):32 |
1 | J:80793 Hippenmeyer S, Shneider NA, Birchmeier C, Burden SJ, Jessell TM, Arber S, A role for neuregulin1 signaling in muscle spindle differentiation. Neuron. 2002 Dec 19;36(6):1035-49 |
1 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1 | J:161851 Honma Y, Kawano M, Kohsaka S, Ogawa M, Axonal projections of mechanoreceptive dorsal root ganglion neurons depend on Ret. Development. 2010 Jul;137(14):2319-28 |
1 | J:70744 Huang EJ, Liu W, Fritzsch B, Bianchi LM, Reichardt LF, Xiang M, Brn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neurons. Development. 2001 Jul;128(13):2421-32 |
1* | J:150882 Ichikawa H, Terayama R, Yamaai T, Jacobowitz DM, Qiu F, Xiang M, Sugimoto T, Brn-3a deficiency transiently increases expression of calbindin D-28 k and calretinin in the trigeminal ganglion during embryonic development. Cell Mol Neurobiol. 2009 Jul;29(5):691-8 |
1 | J:184011 John A, Brylka H, Wiegreffe C, Simon R, Liu P, Juttner R, Crenshaw EB 3rd, Luyten FP, Jenkins NA, Copeland NG, Birchmeier C, Britsch S, Bcl11a is required for neuronal morphogenesis and sensory circuit formation in dorsal spinal cord development. Development. 2012 May;139(10):1831-41 |
1 | J:251343 Kim YJ, Wang SZ, Tymanskyj S, Ma L, Tao HW, Zhang LI, Dcc Mediates Functional Assembly of Peripheral Auditory Circuits. Sci Rep. 2016 Apr 4;6:23799 |
1 | J:77764 Levanon D, Bettoun D, Harris-Cerruti C, Woolf E, Negreanu V, Eilam R, Bernstein Y, Goldenberg D, Xiao C, Fliegauf M, Kremer E, Otto F, Brenner O, Lev-Tov A, Groner Y, The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons. EMBO J. 2002 Jul 1;21(13):3454-63 |
1 | J:344891 Maunsell HR, Ellis K, Kelley MW, Driver EC, Lrrn1 Regulates Medial Boundary Formation in the Developing Mouse Organ of Corti. J Neurosci. 2023 Jul 19;43(29):5305-5318 |
1 | J:231738 Reed-Geaghan EG, Wright MC, See LA, Adelman PC, Lee KH, Koerber HR, Maricich SM, Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. J Neurosci. 2016 Apr 13;36(15):4362-76 |
1 | J:199796 Wang SZ, Ibrahim LA, Kim YJ, Gibson DA, Leung HC, Yuan W, Zhang KK, Tao HW, Ma L, Zhang LI, Slit/Robo Signaling Mediates Spatial Positioning of Spiral Ganglion Neurons during Development of Cochlear Innervation. J Neurosci. 2013 Jul 24;33(30):12242-54 |
Pxdn peroxidasin (Synonyms: 2310075M15Rik, mKIAA0230, VPO1) | |
Results | Reference |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
Pxn paxillin (Synonyms: Pax) | |
Results | Reference |
1* | J:183945 Carlisle FA, Steel KP, Lewis MA, Specific expression of Kcna10, Pxn and Odf2 in the organ of Corti. Gene Expr Patterns. 2012 May;12(5-6):172-9 |
1 | J:280117 Gong X, Guo X, Huang R, Liao H, Zhang Q, Yan J, Luo L, Zhang Q, Qiu A, Sun Y, Liang X, Expression of ILK in renal stroma is essential for multiple aspects of renal development. Am J Physiol Renal Physiol. 2018 Aug 1;315(2):F374-F385 |
Pygb brain glycogen phosphorylase (Synonyms: MGC:36329) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
Pygl liver glycogen phosphorylase | |
Results | Reference |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
Pygm muscle glycogen phosphorylase (Synonyms: PG) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
1 | J:342871 Xiang J, Pompetti AJ, Faranda AP, Wang Y, Novo SG, Li DW, Duncan MK, ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment. Cells. 2023 Nov 16;12(22) |
Pygo1 pygopus 1 (Synonyms: 2600014C22Rik) | |
Results | Reference |
1 | J:305040 Lin L, Xu W, Li Y, Zhu P, Yuan W, Liu M, Shi Y, Chen Y, Liang J, Chen J, Yang B, Cai W, Wen Y, Zhu X, Peng X, Zhou Z, Mo X, Wan Y, Yuan H, Li F, Ye X, Jiang Z, Zhuang J, Wang Y, Wu X, Fan X, Pygo1 regulates pathological cardiac hypertrophy via a beta-catenin-dependent mechanism. Am J Physiol Heart Circ Physiol. 2021 Feb 26;320(4) |
Pygo2 pygopus 2 (Synonyms: 1190004M21Rik, mpygo2) | |
Results | Reference |
1* | J:91606 Li B, Mackay DR, Ma J, Dai X, Cloning and developmental expression of mouse pygopus 2, a putative Wnt signaling component. Genomics. 2004 Aug;84(2):398-405 |
Pyy peptide YY (Synonyms: MGC:19143) | |
Results | Reference |
1 | J:35196 Jackerott M, Oster A, Larsson LI, PYY in developing murine islet cells: comparisons to development of islet hormones, NPY, and BrdU incorporation. J Histochem Cytochem. 1996 Aug;44(8):809-17 |
Qsox1 quiescin Q6 sulfhydryl oxidase 1 (Synonyms: 1300003H02Rik, b2b2673Clo, Qscn6, QSOX) | |
Results | Reference |
1* | J:174484 Portes KF, Ikegami CM, Getz J, Martins AP, de Noronha L, Zischler LF, Klassen G, Camargo AA, Zanata SM, Bevilacqua E, Nakao LS, Tissue distribution of quiescin Q6/sulfhydryl oxidase (QSOX) in developing mouse. J Mol Histol. 2008 Apr;39(2):217-25 |
Rab3a RAB3A, member RAS oncogene family | |
Results | Reference |
1* | J:39412 Dechesne CJ, Kauff C, Stettler O, Tavitian B, Rab3A immunolocalization in the mammalian vestibular end-organs during development and comparison with synaptophysin expression. Brain Res Dev Brain Res. 1997 Mar 17;99(1):103-11 |
1 | J:201069 Stubbusch J, Narasimhan P, Huber K, Unsicker K, Rohrer H, Ernsberger U, Synaptic protein and pan-neuronal gene expression and their regulation by Dicer-dependent mechanisms differ between neurons and neuroendocrine cells. Neural Dev. 2013 Aug 20;8(1):16 |
Rab3b RAB3B, member RAS oncogene family | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Rab4a RAB4A, member RAS oncogene family (Synonyms: Rab4) | |
Results | Reference |
2 | J:241068 Lucitti JL, Sealock R, Buckley BK, Zhang H, Xiao L, Dudley AC, Faber JE, Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke. Stroke. 2016 Dec;47(12):3022-3031 |
Rab5a RAB5A, member RAS oncogene family (Synonyms: 2410015H04Rik) | |
Results | Reference |
1 | J:216175 Cerqueira DM, Tran U, Romaker D, Abreu JG, Wessely O, Sterol carrier protein 2 regulates proximal tubule size in the Xenopus pronephric kidney by modulating lipid rafts. Dev Biol. 2014 Oct 1;394(1):54-64 |
1 | J:150394 Jouret F, Auzanneau C, Debaix H, Wada GH, Pretto C, Marbaix E, Karet FE, Courtoy PJ, Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. J Am Soc Nephrol. 2005 Nov;16(11):3235-46 |
Rab5c RAB5C, member RAS oncogene family | |
Results | Reference |
1* | J:24142 Lutcke A, Jansson S, Parton RG, Chavrier P, Valencia A, Huber LA, Lehtonen E, Zerial M, Rab17, a novel small GTPase, is specific for epithelial cells and is induced during cell polarization. J Cell Biol. 1993 May;121(3):553-64 |
Rab6a RAB6A, member RAS oncogene family (Synonyms: 2610028L11Rik, Rab6) | |
Results | Reference |
1 | J:330973 Brault JB, Bardin S, Lampic M, Carpentieri JA, Coquand L, Penisson M, Lachuer H, Victoria GS, Baloul S, El Marjou F, Boncompain G, Miserey-Lenkei S, Belvindrah R, Fraisier V, Francis F, Perez F, Goud B, Baffet AD, RAB6 and dynein drive post-Golgi apical transport to prevent neuronal progenitor delamination. EMBO Rep. 2022 Oct 6;23(10):e54605 |
Rab6b RAB6B, member RAS oncogene family (Synonyms: C330006L04Rik, D9Bwg0185e) | |
Results | Reference |
1* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
Rab7 RAB7, member RAS oncogene family | |
Results | Reference |
1 | J:216175 Cerqueira DM, Tran U, Romaker D, Abreu JG, Wessely O, Sterol carrier protein 2 regulates proximal tubule size in the Xenopus pronephric kidney by modulating lipid rafts. Dev Biol. 2014 Oct 1;394(1):54-64 |
1 | J:241068 Lucitti JL, Sealock R, Buckley BK, Zhang H, Xiao L, Dudley AC, Faber JE, Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke. Stroke. 2016 Dec;47(12):3022-3031 |
Rab11a RAB11A, member RAS oncogene family | |
Results | Reference |
1 | J:336512 Knapp L, Sun H, Wang YM, Chen BJ, Lin X, Gao N, Chen P, Ren D, Rab11a Is Essential for the Development and Integrity of the Stereocilia and Kinocilia in the Mammalian Organ of Corti. eNeuro. 2023 Jun;10(6):ENEURO.0420-22.2023 |
1 | J:215917 Yu S, Nie Y, Knowles B, Sakamori R, Stypulkowski E, Patel C, Das S, Douard V, Ferraris RP, Bonder EM, Goldenring JR, Ip YT, Gao N, TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis. EMBO J. 2014 Sep 1;33(17):1882-95 |
Rab11b RAB11B, member RAS oncogene family (Synonyms: A730055L17Rik) | |
Results | Reference |
1 | J:336512 Knapp L, Sun H, Wang YM, Chen BJ, Lin X, Gao N, Chen P, Ren D, Rab11a Is Essential for the Development and Integrity of the Stereocilia and Kinocilia in the Mammalian Organ of Corti. eNeuro. 2023 Jun;10(6):ENEURO.0420-22.2023 |
Rab11fip3 RAB11 family interacting protein 3 (class II) (Synonyms: D030060O14Rik, mKIAA0665, Rab11-FIP3) | |
Results | Reference |
1 | J:237778 Hara Y, Fukaya M, Hayashi K, Kawauchi T, Nakajima K, Sakagami H, ADP Ribosylation Factor 6 Regulates Neuronal Migration in the Developing Cerebral Cortex through FIP3/Arfophilin-1-dependent Endosomal Trafficking of N-cadherin. eNeuro. 2016 Jul-Aug;3(4):ENEURO.0148-16.2016 |
Rab11fip4 RAB11 family interacting protein 4 (class II) (Synonyms: A730072L08Rik, mKIAA1821, RAB11-FIP4) | |
Results | Reference |
1 | J:237778 Hara Y, Fukaya M, Hayashi K, Kawauchi T, Nakajima K, Sakagami H, ADP Ribosylation Factor 6 Regulates Neuronal Migration in the Developing Cerebral Cortex through FIP3/Arfophilin-1-dependent Endosomal Trafficking of N-cadherin. eNeuro. 2016 Jul-Aug;3(4):ENEURO.0148-16.2016 |
1* | J:116657 Muto A, Aoki Y, Watanabe S, Mouse Rab11-FIP4 regulates proliferation and differentiation of retinal progenitors in a Rab11-independent manner. Dev Dyn. 2007 Jan;236(1):214-25 |
Rab15 RAB15, member RAS oncogene family (Synonyms: 2310012G06Rik) | |
Results | Reference |
1* | J:174506 Lai HC, Klisch TJ, Roberts R, Zoghbi HY, Johnson JE, In vivo neuronal subtype-specific targets of Atoh1 (Math1) in dorsal spinal cord. J Neurosci. 2011 Jul 27;31(30):10859-71 |
Rab17 RAB17, member RAS oncogene family | |
Results | Reference |
2* | J:24142 Lutcke A, Jansson S, Parton RG, Chavrier P, Valencia A, Huber LA, Lehtonen E, Zerial M, Rab17, a novel small GTPase, is specific for epithelial cells and is induced during cell polarization. J Cell Biol. 1993 May;121(3):553-64 |
Rab18 RAB18, member RAS oncogene family | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:30269 Murphy C, Zerial M, Expression of Rab proteins during mouse embryonic development. Methods Enzymol. 1995;257:324-32 |
Rab23 RAB23, member RAS oncogene family | |
Results | Reference |
1 | J:298641 Hasan MR, Takatalo M, Ma H, Rice R, Mustonen T, Rice DP, RAB23 coordinates early osteogenesis by repressing FGF10-pERK1/2 and GLI1. Elife. 2020 Jul 14;9:e55829 |
Rabep1 rabaptin, RAB GTPase binding effector protein 1 (Synonyms: neurocrescin, RAB5 effector protein, rabaptin-5) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
Rabgef1 RAB guanine nucleotide exchange factor (GEF) 1 (Synonyms: Ras negative regulator Rabex-5) | |
Results | Reference |
2 | J:241068 Lucitti JL, Sealock R, Buckley BK, Zhang H, Xiao L, Dudley AC, Faber JE, Variants of Rab GTPase-Effector Binding Protein-2 Cause Variation in the Collateral Circulation and Severity of Stroke. Stroke. 2016 Dec;47(12):3022-3031 |
Rabl2 RAB, member RAS oncogene family-like 2 (Synonyms: 1110031N17Rik, Rabl2a) | |
Results | Reference |
1 | J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005 |
Rac1 Rac family small GTPase 1 (Synonyms: D5Ertd559e) | |
Results | Reference |
1* | J:320610 Auguste D, Maier M, Baldwin C, Aoudjit L, Robins R, Gupta IR, Takano T, Disease-causing mutations of RhoGDIalpha induce Rac1 hyperactivation in podocytes. Small GTPases. 2016 Apr 2;7(2):107-21 |
1 | J:237425 Danopoulos S, Krainock M, Toubat O, Thornton M, Grubbs B, Al Alam D, Rac1 modulates mammalian lung branching morphogenesis in part through canonical Wnt signaling. Am J Physiol Lung Cell Mol Physiol. 2016 Dec 01;311(6):L1036-L1049 |
2 | J:157099 Grimsley-Myers CM, Sipe CW, Geleoc GS, Lu X, The small GTPase Rac1 regulates auditory hair cell morphogenesis. J Neurosci. 2009 Dec 16;29(50):15859-69 |
1 | J:79013 Hayashi K, Ohshima T, Mikoshiba K, Pak1 is involved in dendrite initiation as a downstream effector of rac1 in cortical neurons. Mol Cell Neurosci. 2002 Aug;20(4):579 |
1 | J:167714 Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, Chen H, Haneline LS, Chan RJ, Schwartz RJ, Field LJ, Atkinson SJ, Shou W, Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development. 2011 Jan;138(2):303-15 |
2 | J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134 |
1 | J:227268 Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Bjorklund P, Mackie K, Di Marzo V, Hokfelt TG, Dobrzyn A, Harkany T, Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6185-94 |
1 | J:197886 Peng X, Lin Q, Liu Y, Jin Y, Druso JE, Antonyak MA, Guan JL, Cerione RA, Inactivation of Cdc42 in embryonic brain results in hydrocephalus with ependymal cell defects in mice. Protein Cell. 2013 Mar;4(3):231-42 |
Rac2 Rac family small GTPase 2 | |
Results | Reference |
1 | J:157099 Grimsley-Myers CM, Sipe CW, Geleoc GS, Lu X, The small GTPase Rac1 regulates auditory hair cell morphogenesis. J Neurosci. 2009 Dec 16;29(50):15859-69 |
Rac3 Rac family small GTPase 3 (Synonyms: Rac1B) | |
Results | Reference |
1 | J:235556 Tivodar S, Kalemaki K, Kounoupa Z, Vidaki M, Theodorakis K, Denaxa M, Kessaris N, de Curtis I, Pachnis V, Karagogeos D, Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons. Cereb Cortex. 2015 Sep;25(9):2370-82 |
Racgap1 Rac GTPase-activating protein 1 (Synonyms: Band25, gtl11, GTPase, MgcRacGAP, mKIAA1478) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
Rack1 receptor for activated C kinase 1 (Synonyms: GB-like, Gnb2l1, Gnb2-rs1, p205) | |
Results | Reference |
1 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
Rad21 RAD21 cohesin complex component (Synonyms: mKIAA0078, SCC1) | |
Results | Reference |
1 | J:211663 Fukuda T, Fukuda N, Agostinho A, Hernandez-Hernandez A, Kouznetsova A, Hoog C, STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. EMBO J. 2014 Jun 2;33(11):1243-55 |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
Rad21l RAD21-like (S. pombe) (Synonyms: Gm14160) | |
Results | Reference |
1 | J:211663 Fukuda T, Fukuda N, Agostinho A, Hernandez-Hernandez A, Kouznetsova A, Hoog C, STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. EMBO J. 2014 Jun 2;33(11):1243-55 |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
Rad51 RAD51 recombinase (Synonyms: Rad51a, Reca) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
1 | J:299451 Atkins A, Xu MJ, Li M, Rogers NP, Pryzhkova MV, Jordan PW, SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. Elife. 2020 Nov 17;9:e61171 |
1 | J:173089 Daniel K, Lange J, Hached K, Fu J, Anastassiadis K, Roig I, Cooke HJ, Stewart AF, Wassmann K, Jasin M, Keeney S, Toth A, Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1. Nat Cell Biol. 2011 May;13(5):599-610 |
1 | J:211663 Fukuda T, Fukuda N, Agostinho A, Hernandez-Hernandez A, Kouznetsova A, Hoog C, STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. EMBO J. 2014 Jun 2;33(11):1243-55 |
1 | J:292630 Holton RA, Harris AM, Mukerji B, Singh T, Dia F, Berkowitz KM, CHTF18 ensures the quantity and quality of the ovarian reserve. Biol Reprod. 2020 Jun 23;103(1):24-35 |
1 | J:326085 Huang TC, Wang YF, Vazquez-Ferrer E, Theofel I, Requena CE, Hanna CW, Kelsey G, Hajkova P, Sex-specific chromatin remodelling safeguards transcription in germ cells. Nature. 2021 Dec;600(7890):737-742 |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
1 | J:213575 Malki S, van der Heijden GW, O'Donnell KA, Martin SL, Bortvin A, A role for retrotransposon LINE-1 in fetal oocyte attrition in mice. Dev Cell. 2014 Jun 9;29(5):521-33 |
1 | J:194101 Yamaguchi S, Hong K, Liu R, Shen L, Inoue A, Diep D, Zhang K, Zhang Y, Tet1 controls meiosis by regulating meiotic gene expression. Nature. 2012 Dec 20;492(7429):443-7 |
Rad54b RAD54 homolog B (S. cerevisiae) (Synonyms: E130016E03Rik) | |
Results | Reference |
1* | J:350102 Yu Y, Zuo X, He M, Gao J, Fu Y, Qin C, Meng L, Wang W, Song Y, Cheng Y, Zhou F, Chen G, Zheng X, Wang X, Liang B, Zhu Z, Fu X, Sheng Y, Hao J, Liu Z, Yan H, Mangold E, Ruczinski I, Liu J, Marazita ML, Ludwig KU, Beaty TH, Zhang X, Sun L, Bian Z, Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity. Nat Commun. 2017 Feb 24;8:14364 |
Raf1 v-raf-leukemia viral oncogene 1 (Synonyms: 6430402F14Rik, c-Raf, Craf1, Raf-1, sarcoma 3611 oncogene, v-Raf) | |
Results | Reference |
1 | J:128917 Provot S, Nachtrab G, Paruch J, Chen AP, Silva A, Kronenberg HM, A-raf and B-raf are dispensable for normal endochondral bone development, and parathyroid hormone-related peptide suppresses extracellular signal-regulated kinase activation in hypertrophic chondrocytes. Mol Cell Biol. 2008 Jan;28(1):344-57 |
Rag1 recombination activating 1 (Synonyms: Rag-1) | |
Results | Reference |
3 | J:84781 Chun JJ, Schatz DG, Oettinger MA, Jaenisch R, Baltimore D, The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system. Cell. 1991 Jan 11;64(1):189-200 |
1* | J:77246 Hicar MD, Robinson ML, Wu LC, Embryonic expression and regulation of the large zinc finger protein KRC. Genesis. 2002 May;33(1):8-20 |
1* | J:49918 Murray AM, Simm B, Beagley KW, Cytokine gene expression in murine fetal intestine: potential for extrathymic T cell development. Cytokine. 1998 May;10(5):337-45 |
1 | J:20032 Schlissel MS, Morrow T, Ig heavy chain protein controls B cell development by regulating germ-line transcription and retargeting V(D)J recombination. J Immunol. 1994 Aug 15;153(4):1645-57 |
Rag2 recombination activating gene 2 (Synonyms: Rag-2) | |
Results | Reference |
1 | J:84781 Chun JJ, Schatz DG, Oettinger MA, Jaenisch R, Baltimore D, The recombination activating gene-1 (RAG-1) transcript is present in the murine central nervous system. Cell. 1991 Jan 11;64(1):189-200 |
1* | J:49918 Murray AM, Simm B, Beagley KW, Cytokine gene expression in murine fetal intestine: potential for extrathymic T cell development. Cytokine. 1998 May;10(5):337-45 |
1 | J:20032 Schlissel MS, Morrow T, Ig heavy chain protein controls B cell development by regulating germ-line transcription and retargeting V(D)J recombination. J Immunol. 1994 Aug 15;153(4):1645-57 |
Rala v-ral simian leukemia viral oncogene A (ras related) (Synonyms: 3010001O15Rik, Ral, Rasl1) | |
Results | Reference |
1* | J:65398 Zhao Z, Rivkees SA, Tissue-specific expression of GTPas RalA and RalB during embryogenesis and regulation by epithelial-mesenchymal interaction. Mech Dev. 2000 Oct;97(1-2):201-4 |
Ralb v-ral simian leukemia viral oncogene B (Synonyms: 5730472O18Rik) | |
Results | Reference |
1* | J:65398 Zhao Z, Rivkees SA, Tissue-specific expression of GTPas RalA and RalB during embryogenesis and regulation by epithelial-mesenchymal interaction. Mech Dev. 2000 Oct;97(1-2):201-4 |
Ralgps2 Ral GEF with PH domain and SH3 binding motif 2 (Synonyms: 1810020P17Rik, 2210408F11Rik, 4921528G01Rik, 9130014M22Rik) | |
Results | Reference |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
Ran RAN, member RAS oncogene family | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
Rangap1 RAN GTPase activating protein 1 (Synonyms: Fug1) | |
Results | Reference |
1* | J:315590 Fujiwara K, Hasegawa K, Oka M, Yoneda Y, Yoshikawa K, Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system. Genes Cells. 2016 Nov;21(11):1176-1194 |
Rapgef1 Rap guanine nucleotide exchange factor (GEF) 1 (Synonyms: 4932418O06Rik, C3G, Grf2) | |
Results | Reference |
1* | J:90089 Ballif BA, Arnaud L, Arthur WT, Guris D, Imamoto A, Cooper JA, Activation of a Dab1/CrkL/C3G/Rap1 pathway in Reelin-stimulated neurons. Curr Biol. 2004 Apr 6;14(7):606-10 |
1* | J:224930 Cheerathodi M, Vincent JJ, Ballif BA, Quantitative comparison of CrkL-SH3 binding proteins from embryonic murine brain and liver: Implications for developmental signaling and the quantification of protein species variants in bottom-up proteomics. J Proteomics. 2015 Jul 1;125:104-11 |
Rapgef2 Rap guanine nucleotide exchange factor (GEF) 2 (Synonyms: 5830453M24Rik, CNRasGEF, mKIAA0313, nRapGEP, Pdzgef1, RA-GEF-1) | |
Results | Reference |
1 | J:313612 Arimura N, Okada M, Taya S, Dewa KI, Tsuzuki A, Uetake H, Miyashita S, Hashizume K, Shimaoka K, Egusa S, Nishioka T, Yanagawa Y, Yamakawa K, Inoue YU, Inoue T, Kaibuchi K, Hoshino M, DSCAM regulates delamination of neurons in the developing midbrain. Sci Adv. 2020 Sep;6(36) |
1 | J:165879 Satyanarayana A, Gudmundsson KO, Chen X, Coppola V, Tessarollo L, Keller JR, Hou SX, RapGEF2 is essential for embryonic hematopoiesis but dispensable for adult hematopoiesis. Blood. 2010 Oct 21;116(16):2921-31 |
Rapgef5 Rap guanine nucleotide exchange factor (GEF) 5 (Synonyms: D030051B22Rik, mKIAA0277, mr-gef) | |
Results | Reference |
1* | J:281432 Alharatani R, Griffin JN, Liu KJ, Expression of the guanine nucleotide exchange factor, RAPGEF5, during mouse and human embryogenesis. Gene Expr Patterns. 2019 Jun 1;34:119057 |
1 | J:160574 Bithell A, Hsu T, Kandanearatchi A, Landau S, Everall IP, Tsuang MT, Chana G, Williams BP, Expression of the Rap1 guanine nucleotide exchange factor, MR-GEF, is altered in individuals with bipolar disorder. PLoS One. 2010;5(4):e10392 |
1 | J:126582 Cobos I, Borello U, Rubenstein JL, Dlx transcription factors promote migration through repression of axon and dendrite growth. Neuron. 2007 Jun 21;54(6):873-88 |
Rapgef6 Rap guanine nucleotide exchange factor (GEF) 6 (Synonyms: C030018K18Rik, Pdzgef2, PDZ-GEF2, RA-GEF-2) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Rapsn receptor-associated protein of the synapse (Synonyms: 43kDa acetylcholine receptor-associated protein, Nraps, Raps, rapsyn) | |
Results | Reference |
1 | J:37005 Noakes PG, Phillips WD, Hanley TA, Sanes JR, Merlie JP, 43K protein and acetylcholine receptors colocalize during the initial stages of neuromuscular synapse formation in vivo. Dev Biol. 1991;155(1):275-80 |
Rara retinoic acid receptor, alpha (Synonyms: RAR alpha 1, RARalpha1) | |
Results | Reference |
1 | J:20940 Bloch-Zupan A, Decimo D, Loriot M, Mark MP, Ruch JV, Expression of nuclear retinoic acid receptors during mouse odontogenesis. Differentiation. 1994 Sep;57(3):195-203 |
1* | J:256937 Bohnenpoll T, Weiss AC, Labuhn M, Ludtke TH, Trowe MO, Kispert A, Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter. Sci Rep. 2017 Nov 1;7(1):14803 |
1 | J:44591 Garel S, Marin F, Grosschedl R, Charnay P, Ebf1 controls early cell differentiation in the embryonic striatum. Development. 1999 Dec;126(23):5285-94 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1* | J:88404 Nishizawa H, Manabe N, Morita M, Sugimoto M, Imanishi S, Miyamoto H, Effects of in utero exposure to bisphenol A on expression of RARalpha and RXRalpha mRNAs in murine embryos. J Reprod Dev. 2003 Dec;49(6):539-45 |
1* | J:80765 Romand R, Hashino E, Dolle P, Vonesch JL, Chambon P, Ghyselinck NB, The retinoic acid receptors RARalpha and RARgamma are required for inner ear development. Mech Dev. 2002 Dec;119(2):213-23 |
1 | J:52596 Toresson H, Mata de Urquiza A, Fagerstrom C, Perlmann T, Campbell K, Retinoids are produced by glia in the lateral ganglionic eminence and regulate striatal neuron differentiation. Development. 1999 Mar;126(6):1317-26 |
2* | J:134349 Vezina CM, Allgeier SH, Fritz WA, Moore RW, Strerath M, Bushman W, Peterson RE, Retinoic acid induces prostatic bud formation. Dev Dyn. 2008 May;237(5):1321-33 |
3* | J:16894 Yamagata T, Momoi MY, Yanagisawa M, Kumagai H, Yamakado M, Momoi T, Changes of the expression and distribution of retinoic acid receptors during neurogenesis in mouse embryos. Brain Res Dev Brain Res. 1994 Feb 18;77(2):163-76 |
Rarb retinoic acid receptor, beta (Synonyms: Hap, RAR beta 2, RARbeta2) | |
Results | Reference |
1 | J:20940 Bloch-Zupan A, Decimo D, Loriot M, Mark MP, Ruch JV, Expression of nuclear retinoic acid receptors during mouse odontogenesis. Differentiation. 1994 Sep;57(3):195-203 |
1* | J:256937 Bohnenpoll T, Weiss AC, Labuhn M, Ludtke TH, Trowe MO, Kispert A, Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter. Sci Rep. 2017 Nov 1;7(1):14803 |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
1* | J:17147 Dolle P, Fraulob V, Kastner P, Chambon P, Developmental expression of murine retinoid X receptor (RXR) genes. Mech Dev. 1994 Feb;45(2):91-104 |
1 | J:44591 Garel S, Marin F, Grosschedl R, Charnay P, Ebf1 controls early cell differentiation in the embryonic striatum. Development. 1999 Dec;126(23):5285-94 |
1 | J:57825 Ghyselinck NB, Bavik C, Sapin V, Mark M, Bonnier D, Hindelang C, Dierich A, Nilsson CB, Hakansson H, Sauvant P, Azais-Braesco V, Frasson M, Picaud S, Chambon P, Cellular retinol-binding protein I is essential for vitamin A homeostasis. EMBO J. 1999 Sep 15;18(18):4903-14 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1 | J:98392 Liao WL, Tsai HC, Wu CY, Liu FC, Differential expression of RARbeta isoforms in the mouse striatum during development: A gradient of RARbeta2 expression along the rostrocaudal axis. Dev Dyn. 2005 Jun;233(2):584-94 |
1* | J:1570 Lyons GE, Houzelstein D, Sassoon D, Robert B, Buckingham ME, Multiple sites of Hox-7 expression during mouse embryogenesis: comparison with retinoic acid receptor mRNA localization. Mol Reprod Dev. 1992 Aug;32(4):303-14 |
1* | J:274711 Niewiadomska-Cimicka A, Krzyzosiak A, Ye T, Podlesny-Drabiniok A, Dembele D, Dolle P, Krezel W, Genome-wide Analysis of RARbeta Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington's Disease and Other Neurodegenerative Disorders. Mol Neurobiol. 2017 Jul;54(5):3859-3878 |
1 | J:192641 Okano J, Levy C, Lichti U, Sun HW, Yuspa SH, Sakai Y, Morasso MI, Cutaneous retinoic acid levels determine hair follicle development and downgrowth. J Biol Chem. 2012 Nov 16;287(47):39304-15 |
1 | J:361958 Straube P, Beckers A, Jany UWH, Bergmann F, Ludtke TH, Rudat C, Trowe MO, Peters I, Klopf MG, Mamo TM, Kispert A, Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter. Development. 2025 Feb 1;152(3) |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1 | J:52596 Toresson H, Mata de Urquiza A, Fagerstrom C, Perlmann T, Campbell K, Retinoids are produced by glia in the lateral ganglionic eminence and regulate striatal neuron differentiation. Development. 1999 Mar;126(6):1317-26 |
2* | J:134349 Vezina CM, Allgeier SH, Fritz WA, Moore RW, Strerath M, Bushman W, Peterson RE, Retinoic acid induces prostatic bud formation. Dev Dyn. 2008 May;237(5):1321-33 |
1* | J:92057 Waclaw RR, Wang B, Campbell K, The homeobox gene Gsh2 is required for retinoid production in the embryonic mouse telencephalon. Development. 2004 Aug;131(16):4013-20 |
3* | J:16894 Yamagata T, Momoi MY, Yanagisawa M, Kumagai H, Yamakado M, Momoi T, Changes of the expression and distribution of retinoic acid receptors during neurogenesis in mouse embryos. Brain Res Dev Brain Res. 1994 Feb 18;77(2):163-76 |
1* | J:22011 Zelent A, Mendelsohn C, Kastner P, Krust A, Garnier JM, Ruffenach F, Leroy P, Chambon P, Differentially expressed isoforms of the mouse retinoic acid receptor beta generated by usage of two promoters and alternative splicing. EMBO J. 1991 Jan;10(1):71-81 |
Rarg retinoic acid receptor, gamma (Synonyms: MGC:11555, MGC:18523, RAR gamma 2, RARgamma2) | |
Results | Reference |
1 | J:20940 Bloch-Zupan A, Decimo D, Loriot M, Mark MP, Ruch JV, Expression of nuclear retinoic acid receptors during mouse odontogenesis. Differentiation. 1994 Sep;57(3):195-203 |
1* | J:256937 Bohnenpoll T, Weiss AC, Labuhn M, Ludtke TH, Trowe MO, Kispert A, Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter. Sci Rep. 2017 Nov 1;7(1):14803 |
1 | J:244957 El Shahawy M, Reibring CG, Neben CL, Hallberg K, Marangoni P, Harfe BD, Klein OD, Linde A, Gritli-Linde A, Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid. PLoS Genet. 2017 Jul;13(7):e1006914 |
1* | J:29563 Giguere V, Shago M, Zirngibl R, Tate P, Rossant J, Varmuza S, Identification of a novel isoform of the retinoic acid receptor gamma expressed in the mouse embryo. Mol Cell Biol. 1990 May;10(5):2335-40 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1* | J:32047 Kastner P, Krust A, Mendelsohn C, Garnier JM, Zelent A, Leroy P, Staub A, Chambon P, Murine isoforms of retinoic acid receptor gamma with specific patterns of expression. Proc Natl Acad Sci U S A. 1990 Apr;87(7):2700-4 |
1* | J:1570 Lyons GE, Houzelstein D, Sassoon D, Robert B, Buckingham ME, Multiple sites of Hox-7 expression during mouse embryogenesis: comparison with retinoic acid receptor mRNA localization. Mol Reprod Dev. 1992 Aug;32(4):303-14 |
1 | J:296563 Schnutgen F, Doerflinger N, Calleja C, Wendling O, Chambon P, Ghyselinck NB, A directional strategy for monitoring Cre-mediated recombination at the cellular level in the mouse. Nat Biotechnol. 2003 May;21(5):562-5 |
2* | J:134349 Vezina CM, Allgeier SH, Fritz WA, Moore RW, Strerath M, Bushman W, Peterson RE, Retinoic acid induces prostatic bud formation. Dev Dyn. 2008 May;237(5):1321-33 |
1* | J:92057 Waclaw RR, Wang B, Campbell K, The homeobox gene Gsh2 is required for retinoid production in the embryonic mouse telencephalon. Development. 2004 Aug;131(16):4013-20 |
2* | J:16894 Yamagata T, Momoi MY, Yanagisawa M, Kumagai H, Yamakado M, Momoi T, Changes of the expression and distribution of retinoic acid receptors during neurogenesis in mouse embryos. Brain Res Dev Brain Res. 1994 Feb 18;77(2):163-76 |
Rarres2 retinoic acid receptor responder (tazarotene induced) 2 (Synonyms: 0610007L05Rik, chemerin) | |
Results | Reference |
1* | J:319569 Ohira T, Spear D, Azimi N, Andreeva V, Yelick PC, Chemerin-ChemR23 signaling in tooth development. J Dent Res. 2012 Dec;91(12):1147-53 |
Rasd2 RASD family, member 2 (Synonyms: 4930526B11Rik, Rhes, TEM-2, TEM2) | |
Results | Reference |
1* | J:91597 Spano D, Branchi I, Rosica A, Pirro MT, Riccio A, Mithbaokar P, Affuso A, Arra C, Campolongo P, Terracciano D, Macchia V, Bernal J, Alleva E, Di Lauro R, Rhes is involved in striatal function. Mol Cell Biol. 2004 Jul;24(13):5788-96 |
Rasgrf1 RAS protein-specific guanine nucleotide-releasing factor 1 (Synonyms: CDC25, CDC25Mm, Grf1, Grfbeta) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Rasgrp2 RAS, guanyl releasing protein 2 (Synonyms: Caldaggef1, CalDAG-GEFI) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Rasl2-9 RAS-like, family 2, locus 9 (Synonyms: Ran/M2, Rasl2-9-ps) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
Rasl11a RAS-like, family 11, member A (Synonyms: 1110065D03Rik) | |
Results | Reference |
1 | J:327415 Jing J, Feng J, Yuan Y, Guo T, Lei J, Pei F, Ho TV, Chai Y, Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022 Aug 16;13(1):4803 |
Rassf1 Ras association (RalGDS/AF-6) domain family member 1 (Synonyms: 123F protein, NORE2A, Rassf1A, Rassf1B, Rassf1C, RDA32, REH3P21) | |
Results | Reference |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Rassf5 Ras association (RalGDS/AF-6) domain family member 5 (Synonyms: 1300019G20Rik, Nore1A, Nore1B, Rapl) | |
Results | Reference |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Raver1 ribonucleoprotein, PTB-binding 1 (Synonyms: 1300006N24Rik) | |
Results | Reference |
1* | J:100326 Kleinhenz B, Fabienke M, Swiniarski S, Wittenmayer N, Kirsch J, Jockusch BM, Arnold HH, Illenberger S, Raver2, a new member of the hnRNP family. FEBS Lett. 2005 Aug 15;579(20):4254-8 |
Raver2 ribonucleoprotein, PTB-binding 2 (Synonyms: A430091O22Rik) | |
Results | Reference |
1* | J:100326 Kleinhenz B, Fabienke M, Swiniarski S, Wittenmayer N, Kirsch J, Jockusch BM, Arnold HH, Illenberger S, Raver2, a new member of the hnRNP family. FEBS Lett. 2005 Aug 15;579(20):4254-8 |
Rax retina and anterior neural fold homeobox (Synonyms: E130303K03Rik, ey1, Rx) | |
Results | Reference |
1 | J:188155 Bharti K, Gasper M, Ou J, Brucato M, Clore-Gronenborn K, Pickel J, Arnheiter H, A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development. PLoS Genet. 2012 Jul;8(7):e1002757 |
1 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
1 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Rb1 RB transcriptional corepressor 1 (Synonyms: pRb, Rb, Rb-1, retinoblastoma 1) | |
Results | Reference |
1* | J:198100 Andreeva V, Cardarelli J, Yelick PC, Rb1 mRNA expression in developing mouse teeth. Gene Expr Patterns. 2012 Mar-Apr;12(3-4):130-5 |
1* | J:97746 Bamba N, Chano T, Taga T, Ohta S, Takeuchi Y, Okabe H, Expression and regulation of RB1CC1 in developing murine and human tissues. Int J Mol Med. 2004 Oct;14(4):583-7 |
1* | J:9980 Bernards R, Schackleford GM, Gerber MR, Horowitz JM, Friend SH, Schartl M, Bogenmann E, Rapaport JM, McGee T, Dryja TP, Weinberg RA, Structure and expression of the murine retinoblastoma gene and characterization of its encoded protein. Proc Natl Acad Sci U S A. 1989 Sep;86(17):6474-8 |
1* | J:108720 Berthet C, Klarmann KD, Hilton MB, Suh HC, Keller JR, Kiyokawa H, Kaldis P, Combined loss of Cdk2 and Cdk4 results in embryonic lethality and Rb hypophosphorylation. Dev Cell. 2006 May;10(5):563-73 |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1* | J:305426 Du G, Oatley MJ, Law NC, Robbins C, Wu X, Oatley JM, Proper timing of a quiescence period in precursor prospermatogonia is required for stem cell pool establishment in the male germline. Development. 2021 May 1;148(9):dev194571 |
1* | J:77762 Ferguson KL, Vanderluit JL, Hebert JM, McIntosh WC, Tibbo E, MacLaurin JG, Park DS, Wallace VA, Vooijs M, McConnell SK, Slack RS, Telencephalon-specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development. EMBO J. 2002 Jul 1;21(13):3337-46 |
1 | J:151321 Glickstein SB, Monaghan JA, Koeller HB, Jones TK, Ross ME, Cyclin D2 is critical for intermediate progenitor cell proliferation in the embryonic cortex. J Neurosci. 2009 Jul 29;29(30):9614-24 |
1* | J:39767 Jiang Z, Zacksenhaus E, Gallie BL, Phillips RA, The retinoblastoma gene family is differentially expressed during embryogenesis. Oncogene. 1997 Apr 17;14(15):1789-97 |
1 | J:113043 Lee EY, Hu N, Yuan SS, Cox LA, Bradley A, Lee WH, Herrup K, Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev. 1994 Sep 1;8(17):2008-21 |
1* | J:82897 Leezer JL, Hackmiller RC, Greene RM, Pisano MM, Expression of the retinoblastoma family of tumor suppressors during murine embryonic orofacial development. Orthod Craniofac Res. 2003 Feb;6(1):32-47 |
2 | J:98518 Mantela J, Jiang Z, Ylikoski J, Fritzsch B, Zacksenhaus E, Pirvola U, The retinoblastoma gene pathway regulates the postmitotic state of hair cells of the mouse inner ear. Development. 2005 May;132(10):2377-88 |
1 | J:316097 Pang L, Tian H, Gao X, Wang W, Wang X, Zhang Z, KMT2D deficiency disturbs the proliferation and cell cycle activity of dental epithelial cell line (LS8) partially via Wnt signaling. Biosci Rep. 2021 Nov 26;41(11) |
1 | J:96345 Sage C, Huang M, Karimi K, Gutierrez G, Vollrath MA, Zhang DS, Garcia-Anoveros J, Hinds PW, Corwin JT, Corey DP, Chen ZY, Proliferation of functional hair cells in vivo in the absence of the retinoblastoma protein. Science. 2005 Feb 18;307(5712):1114-8 |
1* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1 | J:186876 Sugiyama N, Tsukiyama T, Yamaguchi TP, Yokoyama T, The canonical Wnt signaling pathway is not involved in renal cyst development in the kidneys of inv mutant mice. Kidney Int. 2011 May;79(9):957-65 |
1 | J:334078 Wang L, Park JY, Liu F, Olesen KM, Hou S, Peng JC, Infield J, Levesque AC, Wang YD, Jin H, Fan Y, Connelly PJ, Pruett-Miller SM, Hu MG, Hinds PW, Han YG, A kinase-independent function of cyclin-dependent kinase 6 promotes outer radial glia expansion and neocortical folding. Proc Natl Acad Sci U S A. 2022 Sep 20;119(38):e2206147119 |
1 | J:103000 Watanabe R, Chano T, Inoue H, Isono T, Koiwai O, Okabe H, Rb1cc1 is critical for myoblast differentiation through Rb1 regulation. Virchows Arch. 2005 Sep;447(3):643-8 |
1 | J:316651 Zhang W, Vazquez B, Andreeva V, Spear D, Kong E, Hinds PW, Yelick PC, Discrete phosphorylated retinoblastoma protein isoform expression in mouse tooth development. J Mol Histol. 2012 Jun;43(3):281-8 |
1* | J:26610 Zhao J, Nornes HO, Neuman T, Expression of Rb, E2F1, cdc2, and D, and B cyclins in developing spinal cord. Neurosci Lett. 1995 Apr 28;190(1):49-52 |
1 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
Rb1cc1 RB1-inducible coiled-coil 1 (Synonyms: 2900055E04Rik, 5930404L04Rik, Cc1, Fip200, LaXp180, mKIAA0203) | |
Results | Reference |
1* | J:97746 Bamba N, Chano T, Taga T, Ohta S, Takeuchi Y, Okabe H, Expression and regulation of RB1CC1 in developing murine and human tissues. Int J Mol Med. 2004 Oct;14(4):583-7 |
3 | J:196581 Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G, The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-beta signaling. Dev Biol. 2013 May 15;377(2):415-27 |
1 | J:103000 Watanabe R, Chano T, Inoue H, Isono T, Koiwai O, Okabe H, Rb1cc1 is critical for myoblast differentiation through Rb1 regulation. Virchows Arch. 2005 Sep;447(3):643-8 |
Rbbp4 retinoblastoma binding protein 4, chromatin remodeling factor (Synonyms: CAF-1 p48 subunit, RBAP48) | |
Results | Reference |
1 | J:113043 Lee EY, Hu N, Yuan SS, Cox LA, Bradley A, Lee WH, Herrup K, Dual roles of the retinoblastoma protein in cell cycle regulation and neuron differentiation. Genes Dev. 1994 Sep 1;8(17):2008-21 |
1* | J:79495 Yang J, Kiefer S, Rauchman M, Characterization of the gene encoding mouse retinoblastoma binding protein-7, a component of chromatin-remodeling complexes. Genomics. 2002 Oct;80(4):407 |
Rbbp6 retinoblastoma binding protein 6, ubiquitin ligase (Synonyms: 4933422O15Rik, C030034J04Rik) | |
Results | Reference |
1* | J:344233 Wu C, Liu H, Zhan Z, Zhang X, Zhang M, You J, Ma J, Unveiling dysregulated lncRNAs and networks in non-syndromic cleft lip with or without cleft palate pathogenesis. Sci Rep. 2024 Jan 10;14(1):1047 |
Rbbp7 retinoblastoma binding protein 7, chromatin remodeling factor | |
Results | Reference |
1* | J:79495 Yang J, Kiefer S, Rauchman M, Characterization of the gene encoding mouse retinoblastoma binding protein-7, a component of chromatin-remodeling complexes. Genomics. 2002 Oct;80(4):407 |
Rbfox3 RNA binding protein, fox-1 homolog (C. elegans) 3 (Synonyms: D11Bwg0517e, Hrnbp3, NeuN, Neuna60) | |
Results | Reference |
1 | J:181188 Aoki H, Hara A, Era T, Kunisada T, Yamada Y, Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development. 2012 Feb;139(4):667-77 |
1* | J:321845 Bernhardt N, Memic F, Velica A, Tran MA, Vieillard J, Sayyab S, Chersa T, Andersson L, Whelan PJ, Boije H, Kullander K, Hop Mice Display Synchronous Hindlimb Locomotion and a Ventrally Fused Lumbar Spinal Cord Caused by a Point Mutation in Ttc26. eNeuro. 2022 Mar-Apr;9(2):ENEURO.0518-21.2022 |
1 | J:199451 Brunne B, Franco S, Bouche E, Herz J, Howell BW, Pahle J, Muller U, May P, Frotscher M, Bock HH, Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by reelin signaling mutant mice. Glia. 2013 Aug;61(8):1347-63 |
1* | J:318768 Carpentieri JA, Di Cicco A, Lampic M, Andreau D, Del Maestro L, El Marjou F, Coquand L, Bahi-Buisson N, Brault JB, Baffet AD, Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly. Nat Commun. 2022 Jan 10;13(1):16 |
1 | J:182705 Choe Y, Siegenthaler JA, Pleasure SJ, A cascade of morphogenic signaling initiated by the meninges controls corpus callosum formation. Neuron. 2012 Feb 23;73(4):698-712 |
1 | J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400 |
1 | J:213791 Dutta DJ, Zameer A, Mariani JN, Zhang J, Asp L, Huynh J, Mahase S, Laitman BM, Argaw AT, Mitiku N, Urbanski M, Melendez-Vasquez CV, Casaccia P, Hayot F, Bottinger EP, Brown CW, John GR, Combinatorial actions of Tgfbeta and Activin ligands promote oligodendrocyte development and CNS myelination. Development. 2014 Jun;141(12):2414-28 |
1 | J:333383 Funk OH, Qalieh Y, Doyle DZ, Lam MM, Kwan KY, Postmitotic accumulation of histone variant H3.3 in new cortical neurons establishes neuronal chromatin, transcriptome, and identity. Proc Natl Acad Sci U S A. 2022 Aug 9;119(32):e2116956119 |
1 | J:266250 Geng A, Qiu R, Murai K, Liu J, Wu X, Zhang H, Farhoodi H, Duong N, Jiang M, Yee JK, Tsark W, Lu Q, KIF20A/MKLP2 regulates the division modes of neural progenitor cells during cortical development. Nat Commun. 2018 Jul 13;9(1):2707 |
1 | J:133208 Hammerle B, Elizalde C, Tejedor FJ, The spatio-temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrk1A in the developing mouse brain suggests distinct sequential roles in neuronal development. Eur J Neurosci. 2008 Mar;27(5):1061-74 |
1* | J:130971 Hasegawa H, Abbott S, Han BX, Qi Y, Wang F, Analyzing somatosensory axon projections with the sensory neuron-specific Advillin gene. J Neurosci. 2007 Dec 26;27(52):14404-14 |
1 | J:244163 Hasegawa S, Kumagai M, Hagihara M, Nishimaru H, Hirano K, Kaneko R, Okayama A, Hirayama T, Sanbo M, Hirabayashi M, Watanabe M, Hirabayashi T, Yagi T, Distinct and Cooperative Functions for the Protocadherin-alpha, -beta and -gamma Clusters in Neuronal Survival and Axon Targeting. Front Mol Neurosci. 2016;9:155 |
1* | J:190090 Hasegawa S, Kume H, Iinuma S, Yamasaki M, Takahashi N, Fukui T, Acetoacetyl-CoA synthetase is essential for normal neuronal development. Biochem Biophys Res Commun. 2012 Oct 19;427(2):398-403 |
1 | J:256260 Homman-Ludiye J, Kwan WC, de Souza MJ, Rodger J, Bourne JA, Ephrin-A2 regulates excitatory neuron differentiation and interneuron migration in the developing neocortex. Sci Rep. 2017 Sep 18;7(1):11813 |
1* | J:150882 Ichikawa H, Terayama R, Yamaai T, Jacobowitz DM, Qiu F, Xiang M, Sugimoto T, Brn-3a deficiency transiently increases expression of calbindin D-28 k and calretinin in the trigeminal ganglion during embryonic development. Cell Mol Neurobiol. 2009 Jul;29(5):691-8 |
1* | J:32806 Keller-Peck CR, Mullen RJ, Patterns of neuronal differentiation in neural tube mutant mice: curly tail and Pax3 splotch-delayed. J Comp Neurol. 1996 May 13;368(4):516-26 |
1 | J:119015 Kellerer S, Schreiner S, Stolt CC, Scholz S, Bosl MR, Wegner M, Replacement of the Sox10 transcription factor by Sox8 reveals incomplete functional equivalence. Development. 2006 Aug;133(15):2875-86 |
1 | J:234375 Kim H, Jang WY, Kang MC, Jeong J, Choi M, Sung Y, Park S, Kwon W, Jang S, Kim MO, Kim SH, Ryoo ZY, TET1 contributes to neurogenesis onset time during fetal brain development in mice. Biochem Biophys Res Commun. 2016 Mar 18;471(4):437-43 |
1 | J:237344 Lee B, Lee S, Lee SK, Lee JW, The LIM-homeobox transcription factor Isl1 plays crucial roles in the development of multiple arcuate nucleus neurons. Development. 2016 Oct 15;143(20):3763-3773 |
1 | J:94879 Lyu YL, Wang JC, Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase IIbeta. Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7123-8 |
1 | J:177840 Magri L, Cambiaghi M, Cominelli M, Alfaro-Cervello C, Cursi M, Pala M, Bulfone A, Garcia-Verdugo JM, Leocani L, Minicucci F, Poliani PL, Galli R, Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions. Cell Stem Cell. 2011 Nov 4;9(5):447-62 |
1 | J:322988 Markert F, Storch A, Hyperoxygenation During Mid-Neurogenesis Accelerates Cortical Development in the Fetal Mouse Brain. Front Cell Dev Biol. 2022;10:732682 |
1 | J:252094 Matuzelski E, Bunt J, Harkins D, Lim JWC, Gronostajski RM, Richards LJ, Harris L, Piper M, Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord. Dev Biol. 2017 Dec 15;432(2):286-297 |
1 | J:330740 Narayanan R, Pham L, Kerimoglu C, Watanabe T, Castro Hernandez R, Sokpor G, Ulmke PA, Kiszka KA, Tonchev AB, Rosenbusch J, Seong RH, Teichmann U, Frahm J, Fischer A, Bonn S, Stoykova A, Staiger JF, Tuoc T, Chromatin Remodeling BAF155 Subunit Regulates the Genesis of Basal Progenitors in Developing Cortex. iScience. 2018 Jun 29;4:109-126 |
1 | J:187391 Pacal M, Bremner R, Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Dev Dyn. 2012 Oct;241(10):1525-44 |
1 | J:125330 Reis JL, Correia-Pinto J, Monteiro MP, Hutchins GM, In utero topographic analysis of astrocytes and neuronal cells in the spinal cord of mutant mice with myelomeningocele. J Neurosurg. 2007 Jun;106(6 Suppl):472-9 |
1 | J:345833 Rodriguez-Perez LM, Lopez-de-San-Sebastian J, de Diego I, Smith A, Roales-Bujan R, Jimenez AJ, Paez-Gonzalez P, A selective defect in the glial wedge as part of the neuroepithelium disruption in hydrocephalus development in the mouse hyh model is associated with complete corpus callosum dysgenesis. Front Cell Neurosci. 2024;18:1330412 |
1 | J:165741 Rojas A, Schachterle W, Xu SM, Martin F, Black BL, Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer. Dev Biol. 2010 Oct 15;346(2):346-55 |
1 | J:205632 Saito A, Kanemoto S, Kawasaki N, Asada R, Iwamoto H, Oki M, Miyagi H, Izumi S, Sanosaka T, Nakashima K, Imaizumi K, Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun. 2012;3:967 |
1 | J:347366 Saito K, Koike T, Kawashima F, Kurata H, Shibuya T, Satoh T, Hata Y, Yamada H, Mori T, Identification of NeuN immunopositive cells in the adult mouse subventricular zone. J Comp Neurol. 2018 Aug 15;526(12):1927-1942 |
1 | J:316218 Schoof M, Hellwig M, Harrison L, Holdhof D, Lauffer MC, Niesen J, Virdi S, Indenbirken D, Schuller U, The basic helix-loop-helix transcription factor TCF4 impacts brain architecture as well as neuronal morphology and differentiation. Eur J Neurosci. 2020 Jun;51(11):2219-2235 |
1 | J:173596 Sekine K, Honda T, Kawauchi T, Kubo K, Nakajima K, The outermost region of the developing cortical plate is crucial for both the switch of the radial migration mode and the dab1-dependent 'inside-out' lamination in the neocortex. J Neurosci. 2011 Jun 22;31(25):9426-39 |
1 | J:184856 Shintani T, Takeuchi Y, Fujikawa A, Noda M, Directional neuronal migration is impaired in mice lacking adenomatous polyposis coli 2. J Neurosci. 2012 May 9;32(19):6468-84 |
1 | J:241169 Stergiopoulos A, Politis PK, Nuclear receptor NR5A2 controls neural stem cell fate decisions during development. Nat Commun. 2016 Jul 22;7:12230 |
1* | J:82445 Talamillo A, Quinn JC, Collinson JM, Caric D, Price DJ, West JD, Hill RE, Pax6 regulates regional development and neuronal migration in the cerebral cortex. Dev Biol. 2003 Mar 1;255(1):151-63 |
1 | J:309451 Vinsland E, Baskaran P, Mihaylov SR, Hobbs C, Wood H, Bouybayoune I, Shah K, Houart C, Tee AR, Murn J, Fernandes C, Bateman JM, The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021 Aug 11;11(1):16299 |
1 | J:242450 Yang Q, Liu S, Yin M, Yin Y, Zhou G, Zhou J, Ebf2 is required for development of dopamine neurons in the midbrain periaqueductal gray matter of mouse. Dev Neurobiol. 2015 Nov;75(11):1282-94 |
1 | J:195329 Zee T, Boller S, Gyory I, Makinistoglu MP, Tuckermann JP, Grosschedl R, Karsenty G, The transcription factor early B-cell factor 1 regulates bone formation in an osteoblast-nonautonomous manner. FEBS Lett. 2013 Mar 18;587(6):711-6 |
1 | J:251744 Zega K, Jovanovic VM, Vitic Z, Niedzielska M, Knaapi L, Jukic MM, Partanen J, Friedel RF, Lang R, Brodski C, Dusp16 Deficiency Causes Congenital Obstructive Hydrocephalus and Brain Overgrowth by Expansion of the Neural Progenitor Pool. Front Mol Neurosci. 2017;10:372 |
1 | J:326576 Zhang M, Du S, Ou H, Cui R, Jiang N, Lin Y, Ge R, Ma D, Zhang J, Ablation of Zfhx4 results in early postnatal lethality by disrupting the respiratory center in mice. J Mol Cell Biol. 2021 Jul 6;13(3):210-224 |
Rbl1 RB transcriptional corepressor like 1 (Synonyms: p107, retinoblastoma-like 1 (p107)) | |
Results | Reference |
1* | J:82897 Leezer JL, Hackmiller RC, Greene RM, Pisano MM, Expression of the retinoblastoma family of tumor suppressors during murine embryonic orofacial development. Orthod Craniofac Res. 2003 Feb;6(1):32-47 |
1* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1* | J:249296 Spiller CM, Wilhelm D, Koopman P, Retinoblastoma 1 protein modulates XY germ cell entry into G1/G0 arrest during fetal development in mice. Biol Reprod. 2010 Feb;82(2):433-43 |
Rbl2 RB transcriptional corepressor like 2 (Synonyms: p130, Rb2, retinoblastoma-like 2) | |
Results | Reference |
1 | J:32706 Chen G, Guy CT, Chen HW, Hu N, Lee EY, Lee WH, Molecular cloning and developmental expression of mouse p130, a member of the retinoblastoma gene family. J Biol Chem. 1996 Apr 19;271(16):9567-72 |
1* | J:39767 Jiang Z, Zacksenhaus E, Gallie BL, Phillips RA, The retinoblastoma gene family is differentially expressed during embryogenesis. Oncogene. 1997 Apr 17;14(15):1789-97 |
1* | J:82897 Leezer JL, Hackmiller RC, Greene RM, Pisano MM, Expression of the retinoblastoma family of tumor suppressors during murine embryonic orofacial development. Orthod Craniofac Res. 2003 Feb;6(1):32-47 |
1* | J:30594 Pertile P, Baldi A, De Luca A, Bagella L, Virgilio L, Pisano MM, Giordano A, Molecular cloning, expression, and developmental characterization of the murine retinoblastoma-related gene Rb2/p130. Cell Growth Differ. 1995 Dec;6(12):1659-64 |
1* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1* | J:249296 Spiller CM, Wilhelm D, Koopman P, Retinoblastoma 1 protein modulates XY germ cell entry into G1/G0 arrest during fetal development in mice. Biol Reprod. 2010 Feb;82(2):433-43 |
Rbm4 RNA binding motif protein 4 (Synonyms: Lark1, Rbm4a) | |
Results | Reference |
1* | J:265269 Dhananjaya D, Hung KY, Tarn WY, RBM4 Modulates Radial Migration via Alternative Splicing of Dab1 during Cortex Development. Mol Cell Biol. 2018 Jun 15;38(12) |
Rbm8a2 RNA binding motif protein 8A2 (Synonyms: B020018G12Rik, Y14) | |
Results | Reference |
1* | J:104317 Islam S, Montgomery RK, Fialkovich JJ, Grand RJ, Developmental and regional expression and localization of mRNAs encoding proteins involved in RNA translocation. J Histochem Cytochem. 2005 Dec;53(12):1501-9 |
Rbm39 RNA binding motif protein 39 (Synonyms: 1500012C14Rik, 2310040E03Rik, B330012G18Rik, caper, Caper alpha, Rnpc2) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Rbmy RNA binding motif protein, Y chromosome (Synonyms: RBM, Rbm1, Rbm1-rs1, Rbmy1a1, Rbmy1a1-rs1) | |
Results | Reference |
1 | J:46791 Mahadevaiah SK, Odorisio T, Elliott DJ, Rattigan A, Szot M, Laval SH , Washburn LL , McCarrey JR , Cattanach BM , Lovell-Badge R , Burgoyne PS, Mouse homologues of the human AZF candidate gene RBM are expressed in spermatogonia and spermatids, and map to a Y chromosome deletion interval associated with a high incidence of sperm abnormalities. Hum Mol Genet. 1998 Apr;7(4):715-27 |
Rbp1 retinol binding protein 1, cellular (Synonyms: Crbp, CRBPI, Rbp-1) | |
Results | Reference |
1 | J:57825 Ghyselinck NB, Bavik C, Sapin V, Mark M, Bonnier D, Hindelang C, Dierich A, Nilsson CB, Hakansson H, Sauvant P, Azais-Braesco V, Frasson M, Picaud S, Chambon P, Cellular retinol-binding protein I is essential for vitamin A homeostasis. EMBO J. 1999 Sep 15;18(18):4903-14 |
1 | J:121381 Hu P, Zhang M, Napoli JL, Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal. Biochim Biophys Acta. 2007 Apr;1770(4):694-705 |
1 | J:89666 Romand R, Sapin V, Ghyselinck NB, Avan P, Le Calvez S, Dolle P, Chambon P, Mark M, Spatio-temporal distribution of cellular retinoid binding protein gene transcripts in the developing and the adult cochlea. Morphological and functional consequences in CRABP- and CRBPI-null mutant mice. Eur J Neurosci. 2000 Aug;12(8):2793-804 |
1 | J:52596 Toresson H, Mata de Urquiza A, Fagerstrom C, Perlmann T, Campbell K, Retinoids are produced by glia in the lateral ganglionic eminence and regulate striatal neuron differentiation. Development. 1999 Mar;126(6):1317-26 |
Rbp2 retinol binding protein 2, cellular (Synonyms: Crbp-2, CrbpII, Rbp-2) | |
Results | Reference |
1 | J:57825 Ghyselinck NB, Bavik C, Sapin V, Mark M, Bonnier D, Hindelang C, Dierich A, Nilsson CB, Hakansson H, Sauvant P, Azais-Braesco V, Frasson M, Picaud S, Chambon P, Cellular retinol-binding protein I is essential for vitamin A homeostasis. EMBO J. 1999 Sep 15;18(18):4903-14 |
Rbp3 retinol binding protein 3, interstitial (Synonyms: Irbp, Rbp-3) | |
Results | Reference |
1* | J:16741 Liou GI, Wang M, Matragoon S, Timing of interphotoreceptor retinoid-binding protein (IRBP) gene expression and hypomethylation in developing mouse retina. Dev Biol. 1994 Feb;161(2):345-56 |
Rbp4 retinol binding protein 4, plasma (Synonyms: Rbp-4, retinol binding protein 4, cellular) | |
Results | Reference |
2* | J:210139 Hatfield JT, Anderson PJ, Powell BC, Retinol-binding protein 4 is expressed in chondrocytes of developing mouse long bones: implications for a local role in formation of the secondary ossification center. Histochem Cell Biol. 2013 May;139(5):727-34 |
Rbpj recombination signal binding protein for immunoglobulin kappa J region (Synonyms: CBF1, Igkjrb, Igkrsbp, RBPjk, RBP-J kappa, Rbpsuh) | |
Results | Reference |
1 | J:341148 Bosze B, Suarez-Navarro J, Cajias I, Brzezinski Iv JA, Brown NL, Notch pathway mutants do not equivalently perturb mouse embryonic retinal development. PLoS Genet. 2023 Sep;19(9):e1010928 |
1 | J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
2* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:125691 Masui T, Long Q, Beres TM, Magnuson MA, Macdonald RJ, Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex. Genes Dev. 2007 Oct 15;21(20):2629-43 |
1* | J:268318 Miesfeld JB, Moon MS, Riesenberg AN, Contreras AN, Kovall RA, Brown NL, Rbpj direct regulation of Atoh7 transcription in the embryonic mouse retina. Sci Rep. 2018 Jul 5;8(1):10195 |
1 | J:156690 Morimoto M, Liu Z, Cheng HT, Winters N, Bader D, Kopan R, Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate. J Cell Sci. 2010 Jan 15;123(Pt 2):213-24 |
1 | J:269446 Salguero-Jimenez A, Grego-Bessa J, D'Amato G, Jimenez-Borreguero LJ, de la Pompa JL, Myocardial Notch1-Rbpj deletion does not affect NOTCH signaling, heart development or function. PLoS One. 2018;13(12):e0203100 |
1 | J:309104 Zheng MH, Shi M, Pei Z, Gao F, Han H, Ding YQ, The transcription factor RBP-J is essential for retinal cell differentiation and lamination. Mol Brain. 2009 Dec 18;2:38 |
Rbpjl recombination signal binding protein for immunoglobulin kappa J region-like (Synonyms: RBP-J kappa-like, RBP-L, Rbpsuhl) | |
Results | Reference |
1 | J:125691 Masui T, Long Q, Beres TM, Magnuson MA, Macdonald RJ, Early pancreatic development requires the vertebrate Suppressor of Hairless (RBPJ) in the PTF1 bHLH complex. Genes Dev. 2007 Oct 15;21(20):2629-43 |
Rbpms RNA binding protein gene with multiple splicing (Synonyms: 2010300K22Rik, 2700019M19Rik, hermes) | |
Results | Reference |
1* | J:333828 Blommers M, Stanton-Turcotte D, Iulianella A, Retinal neuroblast migration and ganglion cell layer organization require the cytoskeletal-interacting protein Mllt11. Dev Dyn. 2023 Feb;252(2):305-319 |
1 | J:341148 Bosze B, Suarez-Navarro J, Cajias I, Brzezinski Iv JA, Brown NL, Notch pathway mutants do not equivalently perturb mouse embryonic retinal development. PLoS Genet. 2023 Sep;19(9):e1010928 |
1 | J:343468 Li Y, Xiao D, Chen H, Zheng XFS, Xiang M, Maf1 controls retinal neuron number by both RNA Pol III- and Pol II-dependent mechanisms. iScience. 2023 Dec 15;26(12):108544 |
Rbpms2 RNA binding protein with multiple splicing 2 (Synonyms: 2400008B06Rik) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Rbx1 ring-box 1 (Synonyms: 1500002P15Rik, ROC1) | |
Results | Reference |
1 | J:158726 Campos Y, Qiu X, Zanoteli E, Moshiach S, Vergani N, Bongiovanni A, Harris AJ, d'Azzo A, Ozz-E3 ubiquitin ligase targets sarcomeric embryonic myosin heavy chain during muscle development. PLoS One. 2010;5(3):e9866 |
Rcan1 regulator of calcineurin 1 (Synonyms: 2410048A02Rik, ADAPT78, CSP1, Dscr1, MCIP1) | |
Results | Reference |
1* | J:68156 Casas C, Martinez S, Pritchard MA, Fuentes JJ, Nadal M, Guimera J, Arbones M, Florez J, Soriano E, Estivill X, Alcantara S, Dscr1, a novel endogenous inhibitor of calcineurin signaling, is expressed in the primitive ventricle of the heart and during neurogenesis. Mech Dev. 2001 Mar;101(1-2):289-92 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Rcan2 regulator of calcineurin 2 (Synonyms: Csp2, Dscr1l1, MCIP2, ZAKI-4) | |
Results | Reference |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Rcan3 regulator of calcineurin 3 (Synonyms: Csp3, Dscr1l2) | |
Results | Reference |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Rcn3 reticulocalbin 3, EF-hand calcium binding domain (Synonyms: 6030455P07Rik, D530026G20Rik, D7Ertd671e, RLP49) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Rcor1 REST corepressor 1 (Synonyms: 6720480E22Rik, D12Wsu95e, mKIAA0071, Rocr1) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Rcvrn recoverin (Synonyms: cancer associated retinopathy protein, guanylate cyclase activator, S-modulin) | |
Results | Reference |
1* | J:181926 Jo HS, Kang KH, Joe CO, Kim JW, Pten coordinates retinal neurogenesis by regulating Notch signalling. EMBO J. 2012 Feb 15;31(4):817-28 |
Rdh1 retinol dehydrogenase 1 (all trans) | |
Results | Reference |
1 | J:121381 Hu P, Zhang M, Napoli JL, Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal. Biochim Biophys Acta. 2007 Apr;1770(4):694-705 |
Rdh9 retinol dehydrogenase 9 (Synonyms: Crad3) | |
Results | Reference |
2 | J:121381 Hu P, Zhang M, Napoli JL, Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal. Biochim Biophys Acta. 2007 Apr;1770(4):694-705 |
Rdh10 retinol dehydrogenase 10 (all-trans) (Synonyms: 3110069K09Rik, 4921506A21Rik, D1Ertd762e, m366Asp) | |
Results | Reference |
1* | J:125490 Cammas L, Romand R, Fraulob V, Mura C, Dolle P, Expression of the murine retinol dehydrogenase 10 (Rdh10) gene correlates with many sites of retinoid signalling during embryogenesis and organ differentiation. Dev Dyn. 2007 Oct;236(10):2899-908 |
1* | J:137638 Romand R, Kondo T, Cammas L, Hashino E, Dolle P, Dynamic expression of the retinoic acid-synthesizing enzyme retinol dehydrogenase 10 (rdh10) in the developing mouse brain and sensory organs. J Comp Neurol. 2008 Jun 20;508(6):879-92 |
Rdh11 retinol dehydrogenase 11 (Synonyms: 2610319N22Rik, Arsdr1, M42C60, Mdt1, Psdr1) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Rdh16 retinol dehydrogenase 16 (Synonyms: cis-retinol/androgen dehydrogenase 1, CRAD1, Rdh6) | |
Results | Reference |
1 | J:121381 Hu P, Zhang M, Napoli JL, Ontogeny of rdh9 (Crad3) expression: ablation causes changes in retinoid and steroid metabolizing enzymes, but RXR and androgen signaling seem normal. Biochim Biophys Acta. 2007 Apr;1770(4):694-705 |
Rdx radixin | |
Results | Reference |
1 | J:214064 Tarchini B, Jolicoeur C, Cayouette M, A molecular blueprint at the apical surface establishes planar asymmetry in cochlear hair cells. Dev Cell. 2013 Oct 14;27(1):88-102 |
1 | J:346405 Vitureira N, Andres R, Perez-Martinez E, Martinez A, Bribian A, Blasi J, Chelliah S, Lopez-Domenech G, De Castro F, Burgaya F, McNagny K, Soriano E, Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation. PLoS One. 2010 Aug 10;5(8):e12003 |
Rec8 REC8 meiotic recombination protein (Synonyms: mrec, Rec8L1) | |
Results | Reference |
1 | J:211663 Fukuda T, Fukuda N, Agostinho A, Hernandez-Hernandez A, Kouznetsova A, Hoog C, STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. EMBO J. 2014 Jun 2;33(11):1243-55 |
1* | J:215225 Koubova J, Hu YC, Bhattacharyya T, Soh YQ, Gill ME, Goodheart ML, Hogarth CA, Griswold MD, Page DC, Retinoic acid activates two pathways required for meiosis in mice. PLoS Genet. 2014 Aug;10(8):e1004541 |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
1 | J:356085 Wang J, Tian GG, Zheng Z, Li B, Xing Q, Wu J, Comprehensive Transcriptomic Analysis of Mouse Gonadal Development Involving Sexual Differentiation, Meiosis and Gametogenesis. Biol Proced Online. 2019;21:20 |
1 | J:362758 Zhang L, Li Y, Hu Y, Chen M, Cen C, Chen M, Lin L, Zhou J, Wang M, Cui X, Tang F, Gao F, Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression. FASEB J. 2022 Feb;36(2):e22131 |
Reck reversion-inducing-cysteine-rich protein with kazal motifs (Synonyms: St15) | |
Results | Reference |
2 | J:128944 Kawashima S, Imamura Y, Chandana EP, Noda T, Takahashi R, Adachi E, Takahashi C, Noda M, Localization of the membrane-anchored MMP-regulator RECK at the neuromuscular junctions. J Neurochem. 2008 Jan;104(2):376-85 |
1* | J:120755 Kondo S, Shukunami C, Morioka Y, Matsumoto N, Takahashi R, Oh J, Atsumi T, Umezawa A, Kudo A, Kitayama H, Hiraki Y, Noda M, Dual effects of the membrane-anchored MMP regulator RECK on chondrogenic differentiation of ATDC5 cells. J Cell Sci. 2007 Mar 1;120(Pt 5):849-57 |
Redrum Redrum, erythroid developmental long intergenic non-protein coding transcript (Synonyms: 9430076G02Rik) | |
Results | Reference |
1* | J:290519 Lee Y, Park C, Lee S, Lee D, Kim J, Isolation and Functional Examination of the Long Non-Coding RNA Redrum. Mol Cells. 2018 Feb 28;41(2):134-139 |
Reep1 receptor accessory protein 1 (Synonyms: D6Ertd253e) | |
Results | Reference |
1* | J:204006 Beetz C, Koch N, Khundadze M, Zimmer G, Nietzsche S, Hertel N, Huebner AK, Mumtaz R, Schweizer M, Dirren E, Karle KN, Irintchev A, Alvarez V, Redies C, Westermann M, Kurth I, Deufel T, Kessels MM, Qualmann B, Hubner CA, A spastic paraplegia mouse model reveals REEP1-dependent ER shaping. J Clin Invest. 2013 Oct 1;123(10):4273-82 |
Reg2 regenerating islet-derived 2 (Synonyms: pancreatic thread protein) | |
Results | Reference |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Reg3a regenerating islet-derived 3 alpha (Synonyms: RegIII (alpha)) | |
Results | Reference |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
Reg3b regenerating islet-derived 3 beta (Synonyms: Pap, PAP1, REG-III, RegIII (beta)) | |
Results | Reference |
2 | J:54886 Lasserre C, Colnot C, Brechot C, Poirier F, HIP/PAP gene, encoding a C-type lectin overexpressed in primary liver cancer, is expressed in nervous system as well as in intestine and pancreas of the postimplantation mouse embryo. Am J Pathol. 1999 May;154(5):1601-10 |
Reg3g regenerating islet-derived 3 gamma (Synonyms: RegIII (gamma)) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:127539 Joglekar MV, Parekh VS, Mehta S, Bhonde RR, Hardikar AA, MicroRNA profiling of developing and regenerating pancreas reveal post-transcriptional regulation of neurogenin3. Dev Biol. 2007 Nov 15;311(2):603-12 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Rel reticuloendotheliosis oncogene (Synonyms: c-Rel) | |
Results | Reference |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
Rela v-rel reticuloendotheliosis viral oncogene homolog A (avian) (Synonyms: p65, p65 NF kappaB) | |
Results | Reference |
1 | J:173973 Benlhabib H, Mendelson CR, Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia. Mol Cell Biol. 2011 May;31(10):1949-58 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1* | J:60742 Rosenfeld ME, Prichard L, Shiojiri N, Fausto N, Prevention of hepatic apoptosis and embryonic lethality in RelA/TNFR-1 double knockout mice. Am J Pathol. 2000 Mar;156(3):997-1007 |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
1 | J:215917 Yu S, Nie Y, Knowles B, Sakamori R, Stypulkowski E, Patel C, Das S, Douard V, Ferraris RP, Bonder EM, Goldenring JR, Ip YT, Gao N, TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis. EMBO J. 2014 Sep 1;33(17):1882-95 |
Relb avian reticuloendotheliosis viral (v-rel) oncogene related B (Synonyms: shep) | |
Results | Reference |
2 | J:14704 Carrasco D, Ryseck RP, Bravo R, Expression of relB transcripts during lymphoid organ development: specific expression in dendritic antigen-presenting cells. Development. 1993 Aug;118(4):1221-31 |
1 | J:111051 Cui CY, Hashimoto T, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9142-7 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
2 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
2 | J:81255 Yilmaz ZB, Weih DS, Sivakumar V, Weih F, RelB is required for Peyer's patch development: differential regulation of p52-RelB by lymphotoxin and TNF. EMBO J. 2003 Jan 2;22(1):121-30 |
1 | J:215917 Yu S, Nie Y, Knowles B, Sakamori R, Stypulkowski E, Patel C, Das S, Douard V, Ferraris RP, Bonder EM, Goldenring JR, Ip YT, Gao N, TLR sorting by Rab11 endosomes maintains intestinal epithelial-microbial homeostasis. EMBO J. 2014 Sep 1;33(17):1882-95 |
Rell2 RELT-like 2 (Synonyms: 4631403P03Rik, ependolin) | |
Results | Reference |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Reln reelin | |
Results | Reference |
1 | J:50421 Alcantara S, Ruiz M, D'Arcangelo G, Ezan F, de Lecea L, Curran T , Sotelo C , Soriano E, Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse. J Neurosci. 1998 Oct 1;18(19):7779-99 |
2 | J:291525 Amelio I, Panatta E, Niklison-Chirou MV, Steinert JR, Agostini M, Morone N, Knight RA, Melino G, The C terminus of p73 is essential for hippocampal development. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15694-15701 |
1 | J:109820 Arnaud L, Ballif BA, Forster E, Cooper JA, Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development. Curr Biol. 2003 Jan 8;13(1):9-17 |
1 | J:53751 Borrell V, Del Rio JA, Alcantara S, Derer M, Martinez A, D'Arcangelo G, Nakajima K, Mikoshiba K, Derer P, Curran T, Soriano E, Reelin regulates the development and synaptogenesis of the layer-specific entorhino-hippocampal connections. J Neurosci. 1999 Feb 15;19(4):1345-58 |
1 | J:113151 Borrell V, Marin O, Meninges control tangential migration of hem-derived Cajal-Retzius cells via CXCL12/CXCR4 signaling. Nat Neurosci. 2006 Oct;9(10):1284-93 |
1 | J:315303 Bouche E, Romero-Ortega MI, Henkemeyer M, Catchpole T, Leemhuis J, Frotscher M, May P, Herz J, Bock HH, Reelin induces EphB activation. Cell Res. 2013 Apr;23(4):473-90 |
1 | J:199451 Brunne B, Franco S, Bouche E, Herz J, Howell BW, Pahle J, Muller U, May P, Frotscher M, Bock HH, Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by reelin signaling mutant mice. Glia. 2013 Aug;61(8):1347-63 |
1 | J:112971 Camarero G, Tyrsin OY, Xiang C, Pfeiffer V, Pleiser S, Wiese S, Gotz R, Rapp UR, Cortical migration defects in mice expressing A-RAF from the B-RAF locus. Mol Cell Biol. 2006 Oct;26(19):7103-15 |
1 | J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5 |
1 | J:184876 Chiara F, Badaloni A, Croci L, Yeh ML, Cariboni A, Hoerder-Suabedissen A, Consalez GG, Eickholt B, Shimogori T, Parnavelas JG, Rakic S, Early B-cell factors 2 and 3 (EBF2/3) regulate early migration of Cajal-Retzius cells from the cortical hem. Dev Biol. 2012 May 1;365(1):277-89 |
1 | J:227188 Choe Y, Huynh T, Pleasure SJ, Epithelial cells supply Sonic Hedgehog to the perinatal dentate gyrus via transport by platelets. Elife. 2015;4 |
1 | J:158610 Coffinier C, Chang SY, Nobumori C, Tu Y, Farber EA, Toth JI, Fong LG, Young SG, Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):5076-81 |
1 | J:44101 de Bergeyck V, Nakajima K, Lambert de Rouvroit C, Naerhuyzen B, Goffinet AM, Miyata T, Ogawa M, Mikoshiba K, A truncated Reelin protein is produced but not secreted in the Orleans reeler mutation (Reln[rl-Orl]). Brain Res Mol Brain Res. 1997 Oct 15;50(1-2):85-90 |
1 | J:99355 Depaepe V, Suarez-Gonzalez N, Dufour A, Passante L, Gorski JA, Jones KR, Ledent C, Vanderhaeghen P, Ephrin signalling controls brain size by regulating apoptosis of neural progenitors. Nature. 2005 Jun 30;435(7046):1244-50 |
1 | J:299148 Deryckere A, Stappers E, Dries R, Peyre E, van den Berghe V, Conidi A, Zampeta FI, Francis A, Bresseleers M, Stryjewska A, Vanlaer R, Maas E, Smal IV, van IJcken WFJ, Grosveld FG, Nguyen L, Huylebroeck D, Seuntjens E, Multifaceted actions of Zeb2 in postnatal neurogenesis from the ventricular-subventricular zone to the olfactory bulb. Development. 2020 May 26;147(10):dev184861 |
1* | J:268912 Ducharme P, Zarruk JG, David S, Paquin J, The ferroxidase ceruloplasmin influences Reelin processing, cofilin phosphorylation and neuronal organization in the developing brain. Mol Cell Neurosci. 2018 Oct;92:104-113 |
1 | J:112207 Englund C, Kowalczyk T, Daza RA, Dagan A, Lau C, Rose MF, Hevner RF, Unipolar brush cells of the cerebellum are produced in the rhombic lip and migrate through developing white matter. J Neurosci. 2006 Sep 6;26(36):9184-95 |
1 | J:106708 Fink AJ, Englund C, Daza RA, Pham D, Lau C, Nivison M, Kowalczyk T, Hevner RF, Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip. J Neurosci. 2006 Mar 15;26(11):3066-76 |
1* | J:117061 Goebbels S, Bormuth I, Bode U, Hermanson O, Schwab MH, Nave KA, Genetic targeting of principal neurons in neocortex and hippocampus of NEX-Cre mice. Genesis. 2006 Dec;44(12):611-21 |
2 | J:125693 Hanashima C, Fernandes M, Hebert JM, Fishell G, The role of Foxg1 and dorsal midline signaling in the generation of Cajal-Retzius subtypes. J Neurosci. 2007 Oct 10;27(41):11103-11 |
1 | J:87404 Hanashima C, Li SC, Shen L, Lai E, Fishell G, Foxg1 suppresses early cortical cell fate. Science. 2004 Jan 2;303(5654):56-9 |
1 | J:156509 Harrison SJ, Nishinakamura R, Monaghan AP, Sall1 regulates mitral cell development and olfactory nerve extension in the developing olfactory bulb. Cereb Cortex. 2008 Jul;18(7):1604-17 |
1 | J:82656 Hevner RF, Neogi T, Englund C, Daza RA, Fink A, Cajal-Retzius cells in the mouse: transcription factors, neurotransmitters, and birthdays suggest a pallial origin. Brain Res Dev Brain Res. 2003 Mar 14;141(1-2):39-53 |
1 | J:219839 Hirota Y, Kubo K, Katayama K, Honda T, Fujino T, Yamamoto TT, Nakajima K, Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex. J Comp Neurol. 2015 Feb 15;523(3):463-78 |
1 | J:24460 Hirotsune S, Takahara T, Sasaki N, Hirose K, Yoshiki A, Ohashi T, Kusakabe M, Murakami Y, Muramatsu M, Watanabe S, Nakao K, Katsuki M, Hayashizaki, The reeler gene encodes a protein with an EGF-like motif expressed by pioneer neurons [see comments]. Nat Genet. 1995 May;10(1):77-83 |
1 | J:196059 Hodge RD, Garcia AJ 3rd, Elsen GE, Nelson BR, Mussar KE, Reiner SL, Ramirez JM, Hevner RF, Tbr2 expression in Cajal-Retzius cells and intermediate neuronal progenitors is required for morphogenesis of the dentate gyrus. J Neurosci. 2013 Feb 27;33(9):4165-80 |
1* | J:43264 Ikeda Y, Terashima T, Expression of reelin, the gene responsible for the reeler mutation, in embryonic development and adulthood in the mouse. Dev Dyn. 1997 Oct;210(2):157-72 |
1 | J:134970 Inoue T, Ogawa M, Mikoshiba K, Aruga J, Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly. J Neurosci. 2008 Apr 30;28(18):4712-25 |
1* | J:294282 Li L, Ruan X, Wen C, Chen P, Liu W, Zhu L, Xiang P, Zhang X, Wei Q, Hou L, Yin B, Yuan J, Qiang B, Shu P, Peng X, The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019 Jul 16;28(3):698-711.e5 |
1 | J:136385 Li S, Jin Z, Koirala S, Bu L, Xu L, Hynes RO, Walsh CA, Corfas G, Piao X, GPR56 regulates pial basement membrane integrity and cortical lamination. J Neurosci. 2008 May 28;28(22):5817-26 |
1* | J:82121 Luque JM, Morante-Oria J, Fairen A, Localization of ApoER2, VLDLR and Dab1 in radial glia: groundwork for a new model of reelin action during cortical development. Brain Res Dev Brain Res. 2003 Feb 16;140(2):195-203 |
2 | J:94879 Lyu YL, Wang JC, Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase IIbeta. Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7123-8 |
2* | J:74630 Magdaleno S, Keshvara L, Curran T, Rescue of Ataxia and Preplate Splitting by Ectopic Expression of Reelin in reeler Mice. Neuron. 2002 Feb 14;33(4):573-86 |
1 | J:156171 Manuel M, Martynoga B, Yu T, West JD, Mason JO, Price DJ, The transcription factor Foxg1 regulates the competence of telencephalic cells to adopt subpallial fates in mice. Development. 2010 Feb;137(3):487-97 |
1 | J:34807 Miyata T, Nakajima K, Aruga J, Takahashi S, Ikenaka K, Mikoshiba K, Ogawa M, Distribution of a reeler gene-related antigen in the developing cerebellum: an immunohistochemical study with an allogeneic antibody CR-50 on normal and reeler mice. J Comp Neurol. 1996 Aug 19;372(2):215-28 |
1 | J:132671 Moers A, Nurnberg A, Goebbels S, Wettschureck N, Offermanns S, Galpha12/Galpha13 deficiency causes localized overmigration of neurons in the developing cerebral and cerebellar cortices. Mol Cell Biol. 2008 Mar;28(5):1480-8 |
1 | J:232899 Moon UY, Park JY, Park R, Cho JY, Hughes LJ, McKenna J 3rd, Goetzl L, Cho SH, Crino PB, Gambello MJ, Kim S, Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex. Cell Rep. 2015 Aug 11;12(6):965-78 |
1 | J:186443 Muller Smith K, Williamson TL, Schwartz ML, Vaccarino FM, Impaired motor coordination and disrupted cerebellar architecture in Fgfr1 and Fgfr2 double knockout mice. Brain Res. 2012 Jun 15;1460:12-24 |
1 | J:98698 Muzio L, Mallamaci A, Foxg1 confines Cajal-Retzius neuronogenesis and hippocampal morphogenesis to the dorsomedial pallium. J Neurosci. 2005 Apr 27;25(17):4435-41 |
1 | J:203478 Myshrall TD, Moore SA, Ostendorf AP, Satz JS, Kowalczyk T, Nguyen H, Daza RA, Lau C, Campbell KP, Hevner RF, Dystroglycan on radial glia end feet is required for pial basement membrane integrity and columnar organization of the developing cerebral cortex. J Neuropathol Exp Neurol. 2012 Dec;71(12):1047-63 |
1 | J:250180 Nakagawa N, Yagi H, Kato K, Takematsu H, Oka S, Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy. Sci Rep. 2015 Jun 10;5:11163 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1* | J:25502 Ogawa M, Miyata T, Nakajima K, Yagyu K, Seike M, Ikenaka K, Yamamoto H, Mikoshiba K, The reeler gene-associated antigen on Cajal-Retzius neurons is a crucial molecule for laminar organization of cortical neurons. Neuron. 1995 MAY;14(5):899-912 |
1 | J:240398 Ogino H, Hisanaga A, Kohno T, Kondo Y, Okumura K, Kamei T, Sato T, Asahara H, Tsuiji H, Fukata M, Hattori M, Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin. J Neurosci. 2017 Mar 22;37(12):3181-3191 |
2* | J:56295 Ohshima T, Gilmore EC, Longenecker G, Jacobowitz DM, Brady RO, Herrup K, Kulkarni AB, Migration defects of cdk5(-/-) neurons in the developing cerebellum is cell autonomous. J Neurosci. 1999 Jul 15;19(14):6017-26 |
1 | J:150768 Okado H, Ohtaka-Maruyama C, Sugitani Y, Fukuda Y, Ishida R, Hirai S, Miwa A, Takahashi A, Aoki K, Mochida K, Suzuki O, Honda T, Nakajima K, Ogawa M, Terashima T, Matsuda J, Kawano H, Kasai M, The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Dev Biol. 2009 Jul 15;331(2):140-51 |
1 | J:331057 Parichha A, Datta D, Suresh V, Chatterjee M, Holtzman MJ, Tole S, Dentate gyrus morphogenesis is regulated by beta-catenin function in hem-derived fimbrial glia. Development. 2022 Nov 1;149(21):dev200953 |
1 | J:138579 Pawlisz AS, Mutch C, Wynshaw-Boris A, Chenn A, Walsh CA, Feng Y, Lis1-Nde1-dependent neuronal fate control determines cerebral cortical size and lamination. Hum Mol Genet. 2008 Aug 15;17(16):2441-55 |
1* | J:88461 Poirier K, Van Esch H, Friocourt G, Saillour Y, Bahi N, Backer S, Souil E, Castelnau-Ptakhine L, Beldjord C, Francis F, Bienvenu T, Chelly J, Neuroanatomical distribution of ARX in brain and its localisation in GABAergic neurons. Brain Res Mol Brain Res. 2004 Mar 17;122(1):35-46 |
1 | J:127421 Remedios R, Huilgol D, Saha B, Hari P, Bhatnagar L, Kowalczyk T, Hevner RF, Suda Y, Aizawa S, Ohshima T, Stoykova A, Tole S, A stream of cells migrating from the caudal telencephalon reveals a link between the amygdala and neocortex. Nat Neurosci. 2007 Sep;10(9):1141-50 |
2 | J:50400 Rice DS, Sheldon M, D'Arcangelo G, Nakajima K, Goldowitz D, Curran T, Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain. Development. 1998 Sep;125(18):3719-29 |
1 | J:269511 Roy A, Skibo J, Kalume F, Ni J, Rankin S, Lu Y, Dobyns WB, Mills GB, Zhao JJ, Baker SJ, Millen KJ, Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy. Elife. 2015 Dec 3;4:e12703 |
1* | J:41321 Schiffmann SN, Bernier B, Goffinet AM, Reelin mRNA expression during mouse brain development. Eur J Neurosci. 1997 May;9(5):1055-71 |
1 | J:171375 Senturk A, Pfennig S, Weiss A, Burk K, Acker-Palmer A, Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration. Nature. 2011 Apr 21;472(7343):356-60 |
1* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
1 | J:283783 Shu P, Wu C, Ruan X, Liu W, Hou L, Fu H, Wang M, Liu C, Zeng Y, Chen P, Yin B, Yuan J, Qiang B, Peng X, Zhong W, Opposing Gradients of MicroRNA Expression Temporally Pattern Layer Formation in the Developing Neocortex. Dev Cell. 2019 Jun 3;49(5):764-785.e4 |
1* | J:82120 Teillon SM, Yiu G, Walsh CA, Reelin is expressed in the accessory olfactory system, but is not a guidance cue for vomeronasal axons. Brain Res Dev Brain Res. 2003 Feb 16;140(2):303-7 |
1 | J:304564 Venkataramanappa S, Schutz D, Saaber F, Kumar PA, Abe P, Schulz S, Stumm R, The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS Genet. 2021 Mar;17(3):e1009441 |
1 | J:184434 Xiang C, Baubet V, Pal S, Holderbaum L, Tatard V, Jiang P, Davuluri RV, Dahmane N, RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion. Cell Death Differ. 2012 Apr;19(4):692-702 |
1 | J:285763 Xu M, Han X, Liu R, Li Y, Qi C, Yang Z, Zhao C, Gao J, PDK1 Deficit Impairs the Development of the Dentate Gyrus in Mice. Cereb Cortex. 2019 Mar 1;29(3):1185-1198 |
1 | J:270427 Yabut OR, Fernandez G, Huynh T, Yoon K, Pleasure SJ, Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis. Cell Rep. 2015 Sep 29;12(12):2021-34 |
1 | J:281878 Yook C, Kim K, Kim D, Kang H, Kim SG, Kim E, Kim SY, A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice. Front Mol Neurosci. 2019;12:241 |
1 | J:223471 Zhao X, Chen Y, Zhu Q, Huang H, Teng P, Zheng K, Hu X, Xie B, Zhang Z, Sander M, Qiu M, Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor. PLoS One. 2014;9(10):e109171 |
1 | J:324298 Zhou J, Liu G, Zhang X, Wu C, Ma M, Wu J, Hou L, Yin B, Qiang B, Shu P, Peng X, Comparison of the Spatiotemporal Expression Patterns of Three Cre Lines, Emx1IRES-Cre, D6-Cre and hGFAP-Cre, Commonly Used in Neocortical Development Research. Cereb Cortex. 2022 Apr 5;32(8):1668-1681 |
Ren1 renin 1 structural (Synonyms: Ren, Ren-1, Ren1c, Ren1d, Ren-A, Rn-1, Rnr) | |
Results | Reference |
2 | J:362029 Anjum H, Smith JP, Martini AG, Yacu GS, Medrano S, Gomez RA, Sequeira-Lopez MLS, Quaggin SE, Finer G, Tcf21 as a founder transcription factor in specifying Foxd1 cells to the juxtaglomerular cell lineage. Am J Physiol Renal Physiol. 2025 Jan 1;328(1):F121-F130 |
1* | J:218046 Cuffe JS, Walton SL, Steane SE, Singh RR, Simmons DG, Moritz KM, The effects of gestational age and maternal hypoxia on the placental renin angiotensin system in the mouse. Placenta. 2014 Nov;35(11):953-61 |
1 | J:321844 Mochida Y, Ochiai K, Nagase T, Nonomura K, Akimoto Y, Fukuhara H, Sakai T, Matsumura G, Yamaguchi Y, Nagase M, Piezo2 expression and its alteration by mechanical forces in mouse mesangial cells and renin-producing cells. Sci Rep. 2022 Mar 10;12(1):4197 |
1 | J:67267 Perera EM, Martin H, Seeherunvong T, Kos L, Hughes IA, Hawkins JR, Berkovitz GD, Tescalcin, a novel gene encoding a putative EF-hand Ca(2+)-binding protein, Col9a3, and renin are expressed in the mouse testis during the early stages of gonadal differentiation. Endocrinology. 2001 Jan;142(1):455-63 |
1* | J:308609 Sararols P, Stevant I, Neirijnck Y, Rebourcet D, Darbey A, Curley MK, Kuhne F, Dermitzakis E, Smith LB, Nef S, Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells. Front Cell Dev Biol. 2021;9:695546 |
2 | J:127938 Sauter A, Machura K, Neubauer B, Kurtz A, Wagner C, Development of renin expression in the mouse kidney. Kidney Int. 2008 Jan;73(1):43-51 |
1 | J:70875 Sequeira Lopez ML, Pentz ES, Robert B, Abrahamson DR, Gomez RA, Embryonic origin and lineage of juxtaglomerular cells. Am J Physiol Renal Physiol. 2001 Aug;281(2):F345-56 |
1 | J:227281 Sequeira-Lopez ML, Nagalakshmi VK, Li M, Sigmund CD, Gomez RA, Vascular versus tubular renin: role in kidney development. Am J Physiol Regul Integr Comp Physiol. 2015 Sep 15;309(6):R650-7 |
1* | J:160194 Shaw L, Johnson PA, Kimber SJ, Gene expression profiling of the developing mouse kidney and embryo. In Vitro Cell Dev Biol Anim. 2010 Feb;46(2):155-65 |
Ren2 renin 2 tandem duplication of Ren1 (Synonyms: Ren, Ren-2, Ren-B, Rn-2, Rnr) | |
Results | Reference |
1 | J:67267 Perera EM, Martin H, Seeherunvong T, Kos L, Hughes IA, Hawkins JR, Berkovitz GD, Tescalcin, a novel gene encoding a putative EF-hand Ca(2+)-binding protein, Col9a3, and renin are expressed in the mouse testis during the early stages of gonadal differentiation. Endocrinology. 2001 Jan;142(1):455-63 |
1 | J:70875 Sequeira Lopez ML, Pentz ES, Robert B, Abrahamson DR, Gomez RA, Embryonic origin and lineage of juxtaglomerular cells. Am J Physiol Renal Physiol. 2001 Aug;281(2):F345-56 |
Resf1 retroelement silencing factor 1 (Synonyms: 2810474O19Rik, 6720435I21Rik, GET) | |
Results | Reference |
2* | J:98793 Hudson QJ, Smith CA, Sinclair AH, Conserved expression of a novel gene during gonadal development. Dev Dyn. 2005 Apr 28;233(3):1083-1090 |
Rest RE1-silencing transcription factor (Synonyms: 2610008J04Rik, NRSF) | |
Results | Reference |
1 | J:181188 Aoki H, Hara A, Era T, Kunisada T, Yamada Y, Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development. 2012 Feb;139(4):667-77 |
1 | J:187349 Hu XL, Cheng X, Cai L, Tan GH, Xu L, Feng XY, Lu TJ, Xiong H, Fei J, Xiong ZQ, Conditional deletion of NRSF in forebrain neurons accelerates epileptogenesis in the kindling model. Cereb Cortex. 2011 Sep;21(9):2158-65 |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1* | J:281311 Nakano Y, Wiechert S, Banfi B, Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8 |
1 | J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12) |
1 | J:321932 Rovira M, Atla G, Maestro MA, Grau V, Garcia-Hurtado J, Maqueda M, Mosquera JL, Yamada Y, Kerr-Conte J, Pattou F, Ferrer J, REST is a major negative regulator of endocrine differentiation during pancreas organogenesis. Genes Dev. 2021 Sep 1;35(17-18):1229-1242 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Ret ret proto-oncogene (Synonyms: c-Ret, RET51, RET9) | |
Results | Reference |
1* | J:82111 Allmendinger A, Stoeckel E, Saarma M, Unsicker K, Huber K, Development of adrenal chromaffin cells is largely normal in mice lacking the receptor tyrosine kinase c-Ret. Mech Dev. 2003 Mar;120(3):299-304 |
1 | J:333984 Altes G, Vaquero M, Cuesta S, Anerillas C, Macia A, Espinet C, Ribera J, Bellusci S, Klein OD, Yeramian A, Dolcet X, Egea J, Encinas M, A dominant negative mutation uncovers cooperative control of caudal Wolffian duct development by Sprouty genes. Cell Mol Life Sci. 2022 Sep 13;79(10):514 |
1 | J:64589 Baudet C, Mikaels A, Westphal H, Johansen J, Johansen TE, Ernfors P, Positive and negative interactions of GDNF, NTN and ART in developing sensory neuron subpopulations, and their collaboration with neurotrophins. Development. 2000 Oct;127(20):4335-44 |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1 | J:166770 Coppola E, d'Autreaux F, Rijli FM, Brunet JF, Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation. Development. 2010 Dec;137(24):4211-20 |
1 | J:126634 Coppola E, Pattyn A, Guthrie SC, Goridis C, Studer M, Reciprocal gene replacements reveal unique functions for Phox2 genes during neural differentiation. EMBO J. 2005 Dec 21;24(24):4392-403 |
1 | J:30057 Dudley AT, Lyons KM, Robertson EJ, A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev. 1995 NOV 15;9(22):2795-2807 |
1 | J:235934 Fleming MS, Li JJ, Ramos D, Li T, Talmage DA, Abe SI, Arber S, Luo W, A RET-ER81-NRG1 Signaling Pathway Drives the Development of Pacinian Corpuscles. J Neurosci. 2016 Oct 5;36(40):10337-10355 |
1 | J:132854 Gould TW, Yonemura S, Oppenheim RW, Ohmori S, Enomoto H, The neurotrophic effects of glial cell line-derived neurotrophic factor on spinal motoneurons are restricted to fusimotor subtypes. J Neurosci. 2008 Feb 27;28(9):2131-46 |
3 | J:196581 Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G, The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-beta signaling. Dev Biol. 2013 May 15;377(2):415-27 |
1 | J:345844 Guo Y, Xiang P, Sun X, Liu W, Zhou J, Yin B, Hou L, Qiang B, Li H, Shu P, Peng X, Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy. Signal Transduct Target Ther. 2024 Feb 14;9(1):32 |
1 | J:161851 Honma Y, Kawano M, Kohsaka S, Ogawa M, Axonal projections of mechanoreceptive dorsal root ganglion neurons depend on Ret. Development. 2010 Jul;137(14):2319-28 |
1 | J:79390 Huber K, Bruhl B, Guillemot F, Olson EN, Ernsberger U, Unsicker K, Development of chromaffin cells depends on MASH1 function. Development. 2002 Oct;129(20):4729-38 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
1* | J:228878 Kosfeld A, Kreuzer M, Daniel C, Brand F, Schafer AK, Chadt A, Weiss AC, Riehmer V, Jeanpierre C, Klintschar M, Brasen JH, Amann K, Pape L, Kispert A, Al-Hasani H, Haffner D, Weber RG, Whole-exome sequencing identifies mutations of TBC1D1 encoding a Rab-GTPase-activating protein in patients with congenital anomalies of the kidneys and urinary tract (CAKUT). Hum Genet. 2016 Jan;135(1):69-87 |
1 | J:44407 Luukko K, Suvanto P, Saarma M, Thesleff I, Expression of GDNF and its receptors in developing tooth is developmentally regulated and suggests multiple roles in innervation and organogenesis. Dev Dyn. 1997 Dec;210(4):463-71 |
1 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
1 | J:120229 Narlis M, Grote D, Gaitan Y, Boualia SK, Bouchard M, Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney. J Am Soc Nephrol. 2007 Apr;18(4):1121-9 |
1* | J:57342 Nishino J, Mochida K, Ohfuji Y, Shimazaki T, Meno C, Ohishi S, Matsuda Y, Fujii H, Saijoh Y, Hamada H, GFR alpha3, a component of the artemin receptor, is required for migration and survival of the superior cervical ganglion. Neuron. 1999 Aug;23(4):725-36 |
1* | J:16246 Pachnis V, Mankoo B, Costantini F, Expression of the c-ret proto-oncogene during mouse embryogenesis. Development. 1993 Dec;119(4):1005-17 |
1 | J:223235 Park HJ, Bolton EC, Glial cell line-derived neurotrophic factor induces cell proliferation in the mouse urogenital sinus. Mol Endocrinol. 2015 Feb;29(2):289-306 |
1 | J:60124 Pitera JE, Smith VV, Thorogood P, Milla PJ, Coordinated expression of 3' hox genes during murine embryonal gut development: an enteric Hox code. Gastroenterology. 1999 Dec;117(6):1339-51 |
1* | J:241573 Pui HP, Saga Y, Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling. Mech Dev. 2017 Apr;144(Pt B):125-139 |
1 | J:231738 Reed-Geaghan EG, Wright MC, See LA, Adelman PC, Lee KH, Koerber HR, Maricich SM, Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. J Neurosci. 2016 Apr 13;36(15):4362-76 |
1 | J:331367 Roussel J, Larcher R, Sicard P, Bideaux P, Richard S, Marmigere F, Thireau J, The autism-associated Meis2 gene is necessary for cardiac baroreflex regulation in mice. Sci Rep. 2022 Nov 23;12(1):20150 |
1 | J:197538 Sasselli V, Boesmans W, Vanden Berghe P, Tissir F, Goffinet AM, Pachnis V, Planar cell polarity genes control the connectivity of enteric neurons. J Clin Invest. 2013 Apr 1;123(4):1763-72 |
2 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
1 | J:73864 Wallen A A, Castro DS, Zetterstrom RH, Karlen M, Olson L, Ericson J, Perlmann T, Orphan nuclear receptor Nurr1 is essential for Ret expression in midbrain dopamine neurons and in the brain stem. Mol Cell Neurosci. 2001 Dec;18(6):649-63 |
2 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
1 | J:81003 Young HM, Bergner AJ, Muller T, Acquisition of neuronal and glial markers by neural crest-derived cells in the mouse intestine. J Comp Neurol. 2003 Jan 27;456(1):1-11 |
Rfng RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase (Synonyms: radical fringe) | |
Results | Reference |
1 | J:63320 Favier B, Fliniaux I, Thelu J, Viallet JP, Demarchez M, Jahoda CA, Dhouailly D, Localisation of members of the notch system and the differentiation of vibrissa hair follicles: receptors, ligands, and fringe modulators. Dev Dyn. 2000 Jul;218(3):426-37 |
1* | J:60388 Ishii Y, Nakamura S, Osumi N, Demarcation of early mammalian cortical development by differential expression of fringe genes. Brain Res Dev Brain Res. 2000 Feb 7;119(2):307-20 |
1 | J:50796 Thelu J, Viallet JP, Dhouailly D, Differential expression pattern of the three Fringe genes is associated with epidermal differentiation. J Invest Dermatol. 1998 Nov;111(5):903-6 |
Rftn2 raftlin family member 2 (Synonyms: 2700010E02Rik, 3222401M22Rik) | |
Results | Reference |
1* | J:333712 Liang J, Liang J, Tan Q, Wang Z, ELAC2 Functions as a Key Gene in the Early Development of Placental Formation Based on WGCNA. Cells. 2023 Feb 14;12(4) |
Rfx1 regulatory factor X, 1 (influences HLA class II expression) | |
Results | Reference |
1 | J:291604 Li J, Zhang T, Ramakrishnan A, Fritzsch B, Xu J, Wong EYM, Loh YE, Ding J, Shen L, Xu PX, Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium. Nucleic Acids Res. 2020 Apr 6;48(6):2880-2896 |
Rfx2 regulatory factor X, 2 (influences HLA class II expression) (Synonyms: 5430432H19Rik) | |
Results | Reference |
1 | J:291604 Li J, Zhang T, Ramakrishnan A, Fritzsch B, Xu J, Wong EYM, Loh YE, Ding J, Shen L, Xu PX, Dynamic changes in cis-regulatory occupancy by Six1 and its cooperative interactions with distinct cofactors drive lineage-specific gene expression programs during progressive differentiation of the auditory sensory epithelium. Nucleic Acids Res. 2020 Apr 6;48(6):2880-2896 |
Rfx3 regulatory factor X, 3 (influences HLA class II expression) (Synonyms: C230093O12Rik, MRFX3) | |
Results | Reference |
1 | J:183848 Benadiba C, Magnani D, Niquille M, Morle L, Valloton D, Nawabi H, Ait-Lounis A, Otsmane B, Reith W, Theil T, Hornung JP, Lebrand C, Durand B, The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development. PLoS Genet. 2012 Mar;8(3):e1002606 |
Rfx4 regulatory factor X, 4 (influences HLA class II expression) (Synonyms: 4933412G19Rik) | |
Results | Reference |
1* | J:84751 Blackshear PJ, Graves JP, Stumpo DJ, Cobos I, Rubenstein JL, Zeldin DC, Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4. Development. 2003 Oct;130(19):4539-52 |
Rgma repulsive guidance molecule family member A (Synonyms: MGC:38550, MGC:69915, RGM domain family, member A) | |
Results | Reference |
1 | J:235517 Kam JW, Dumontier E, Baim C, Brignall AC, Mendes da Silva D, Cowan M, Kennedy TE, Cloutier JF, RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016 May 1;143(9):1534-46 |
2* | J:199400 van den Heuvel DM, Hellemons AJ, Pasterkamp RJ, Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain. PLoS One. 2013;8(2):e55828 |
1 | J:227692 van Erp S, van den Heuvel DM, Fujita Y, Robinson RA, Hellemons AJ, Adolfs Y, Van Battum EY, Blokhuis AM, Kuijpers M, Demmers JA, Hedman H, Hoogenraad CC, Siebold C, Yamashita T, Pasterkamp RJ, Lrig2 Negatively Regulates Ectodomain Shedding of Axon Guidance Receptors by ADAM Proteases. Dev Cell. 2015 Dec 7;35(5):537-52 |
Rgmb repulsive guidance molecule family member B (Synonyms: 1110059F19Rik, DRAGON, RGM domain family, member B) | |
Results | Reference |
3 | J:235517 Kam JW, Dumontier E, Baim C, Brignall AC, Mendes da Silva D, Cowan M, Kennedy TE, Cloutier JF, RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016 May 1;143(9):1534-46 |
2 | J:315293 Kumamoto T, Toma K, Gunadi, McKenna WL, Kasukawa T, Katzman S, Chen B, Hanashima C, Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013 Mar 28;3(3):931-45 |
1* | J:87768 Niederkofler V, Salie R, Sigrist M, Arber S, Repulsive guidance molecule (RGM) gene function is required for neural tube closure but not retinal topography in the mouse visual system. J Neurosci. 2004 Jan 28;24(4):808-18 |
2* | J:199400 van den Heuvel DM, Hellemons AJ, Pasterkamp RJ, Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain. PLoS One. 2013;8(2):e55828 |
Rgs2 regulator of G-protein signaling 2 (Synonyms: GOS8) | |
Results | Reference |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1* | J:95375 Wilson LD, Ross SA, Lepore DA, Wada T, Penninger JM, Thomas PQ, Developmentally regulated expression of the regulator of G-protein signaling gene 2 (Rgs2) in the embryonic mouse pituitary. Gene Expr Patterns. 2005 Feb;5(3):305-11 |
Rgs3 regulator of G-protein signaling 3 (Synonyms: 4930506N09Rik, C2pa, C2PA-RGS3, PDZ-RGS3, RGS3S) | |
Results | Reference |
1* | J:64314 Linares JL, Wendling C, Tomasetto C, Rio MC, C2PA, a new protein expressed during mouse spermatogenesis. FEBS Lett. 2000 Sep 1;480(2-3):249-54 |
1 | J:68850 Lu Q, Sun EE, Klein RS, Flanagan JG, Ephrin-B reverse signaling is mediated by a novel PDZ-RGS protein and selectively inhibits G protein-coupled chemoattraction. Cell. 2001 Apr 6;105(1):69-79 |
Rgs4 regulator of G-protein signaling 4 (Synonyms: ESTM48, ESTM50) | |
Results | Reference |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Rgs5 regulator of G-protein signaling 5 (Synonyms: 1110070A02Rik) | |
Results | Reference |
1* | J:329933 Akkuratova N, Faure L, Kameneva P, Kastriti ME, Adameyko I, Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics. Front Endocrinol (Lausanne). 2022;13:1020000 |
1 | J:196361 Cappellari O, Benedetti S, Innocenzi A, Tedesco FS, Moreno-Fortuny A, Ugarte G, Lampugnani MG, Messina G, Cossu G, Dll4 and PDGF-BB convert committed skeletal myoblasts to pericytes without erasing their myogenic memory. Dev Cell. 2013 Mar 25;24(6):586-99 |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Rgs6 regulator of G-protein signaling 6 | |
Results | Reference |
1* | J:306155 Goodyer WR, Beyersdorf BM, Paik DT, Tian L, Li G, Buikema JW, Chirikian O, Choi S, Venkatraman S, Adams EL, Tessier-Lavigne M, Wu JC, Wu SM, Transcriptomic Profiling of the Developing Cardiac Conduction System at Single-Cell Resolution. Circ Res. 2019 Aug 2;125(4):379-397 |
Rgs12 regulator of G-protein signaling 12 (Synonyms: 1200016K18Rik, 4632412M04Rik) | |
Results | Reference |
1 | J:330604 Akturk A, Day M, Tarchini B, RGS12 polarizes the GPSM2-GNAI complex to organize and elongate stereocilia in sensory hair cells. Sci Adv. 2022 Oct 21;8(42):eabq2826 |
Rhbdf1 rhomboid 5 homolog 1 (Synonyms: Dist, Dist1, Egfr-rs) | |
Results | Reference |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1 | J:317051 Tushaus J, Muller SA, Shrouder J, Arends M, Simons M, Plesnila N, Blobel CP, Lichtenthaler SF, The pseudoprotease iRhom1 controls ectodomain shedding of membrane proteins in the nervous system. FASEB J. 2021 Nov;35(11):e21962 |
Rhbdl3 rhomboid like 3 (Synonyms: Rhbdl4, Ventrhoid, Vrho) | |
Results | Reference |
1 | J:339937 Smith KS, Bihannic L, Gudenas BL, Haldipur P, Tao R, Gao Q, Li Y, Aldinger KA, Iskusnykh IY, Chizhikov VV, Scoggins M, Zhang S, Edwards A, Deng M, Glass IA, Overman LM, Millman J, Sjoboen AH, Hadley J, Golser J, Mankad K, Sheppard H, Onar-Thomas A, Gajjar A, Robinson GW, Hovestadt V, Orr BA, Patay Z, Millen KJ, Northcott PA, Unified rhombic lip origins of group 3 and group 4 medulloblastoma. Nature. 2022 Sep;609(7929):1012-1020 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Rheb Ras homolog enriched in brain (Synonyms: Rheb1) | |
Results | Reference |
1 | J:168571 Zou J, Zhou L, Du XX, Ji Y, Xu J, Tian J, Jiang W, Zou Y, Yu S, Gan L, Luo M, Yang Q, Cui Y, Yang W, Xia X, Chen M, Zhao X, Shen Y, Chen PY, Worley PF, Xiao B, Rheb1 is required for mTORC1 and myelination in postnatal brain development. Dev Cell. 2011 Jan 18;20(1):97-108 |
Rho rhodopsin (Synonyms: Long Wavelength Sensitive opsin, L opsin, LWS opsin, MGC:21585, MGC:25387, Noerg1, Opn2, Ops, opsin 2, Red Opsin, Rod Opsin, RP4) | |
Results | Reference |
1* | J:16741 Liou GI, Wang M, Matragoon S, Timing of interphotoreceptor retinoid-binding protein (IRBP) gene expression and hypomethylation in developing mouse retina. Dev Biol. 1994 Feb;161(2):345-56 |
1* | J:71808 Swain PK, Hicks D, Mears AJ, Apel IJ, Smith JE, John SK, Hendrickson A, Milam AH, Swaroop A, Multiple phosphorylated isoforms of NRL are expressed in rod photoreceptors. J Biol Chem. 2001 Sep 28;276(39):36824-30 |
1 | J:108702 Zhang CL, Zou Y, Yu RT, Gage FH, Evans RM, Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes Dev. 2006 May 15;20(10):1308-20 |
1* | J:120114 Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY, A biphasic pattern of gene expression during mouse retina development. BMC Dev Biol. 2006;6:48 |
Rhoa ras homolog family member A (Synonyms: Arha, Arha1, Arha2, RhoA) | |
Results | Reference |
1 | J:79013 Hayashi K, Ohshima T, Mikoshiba K, Pak1 is involved in dendrite initiation as a downstream effector of rac1 in cortical neurons. Mol Cell Neurosci. 2002 Aug;20(4):579 |
1* | J:314287 Leslie JR, Imai F, Zhou X, Lang RA, Zheng Y, Yoshida Y, RhoA is dispensable for axon guidance of sensory neurons in the mouse dorsal root ganglia. Front Mol Neurosci. 2012;5:67 |
1 | J:167714 Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, Chen H, Haneline LS, Chan RJ, Schwartz RJ, Field LJ, Atkinson SJ, Shou W, Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development. 2011 Jan;138(2):303-15 |
1 | J:346405 Vitureira N, Andres R, Perez-Martinez E, Martinez A, Bribian A, Blasi J, Chelliah S, Lopez-Domenech G, De Castro F, Burgaya F, McNagny K, Soriano E, Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation. PLoS One. 2010 Aug 10;5(8):e12003 |
1 | J:306543 Yu Z, Zeng J, Wang J, Cui Y, Song X, Zhang Y, Cheng X, Hou N, Teng Y, Lan Y, Chen Y, Yang X, Hepatocyte growth factor-regulated tyrosine kinase substrate is essential for endothelial cell polarity and cerebrovascular stability. Cardiovasc Res. 2021 Jan 21;117(2):533-546 |
1* | J:105879 Zhang TJ, Hoffman BG, Ruiz de Algara T, Helgason CD, SAGE reveals expression of Wnt signalling pathway members during mouse prostate development. Gene Expr Patterns. 2006 Mar;6(3):310-24 |
Rhobtb2 Rho-related BTB domain containing 2 (Synonyms: Dbc2, E130206H14Rik, mKIAA0717) | |
Results | Reference |
2* | J:94055 St-Pierre B, Jiang Z, Egan SE, Zacksenhaus E, High expression during neurogenesis but not mammogenesis of a murine homologue of the Deleted in Breast Cancer2/Rhobtb2 tumor suppressor. Gene Expr Patterns. 2004 Dec;5(2):245-251 |
Rhod ras homolog family member D (Synonyms: Arhd) | |
Results | Reference |
1 | J:266104 Choi JH, Jo HS, Lim S, Kim HT, Lee KW, Moon KH, Ha T, Kwak SS, Kim Y, Lee EJ, Joe CO, Kim JW, mTORC1 accelerates retinal development via the immunoproteasome. Nat Commun. 2018 Jun 27;9(1):2502 |
Rhog ras homolog family member G (Synonyms: 2810426G09Rik, Arhg, RhoG, Sid10750) | |
Results | Reference |
1 | J:346405 Vitureira N, Andres R, Perez-Martinez E, Martinez A, Bribian A, Blasi J, Chelliah S, Lopez-Domenech G, De Castro F, Burgaya F, McNagny K, Soriano E, Podocalyxin is a novel polysialylated neural adhesion protein with multiple roles in neural development and synapse formation. PLoS One. 2010 Aug 10;5(8):e12003 |
Rhoj ras homolog family member J (Synonyms: 1110005O19Rik, Arhj, TC10L, TCL) | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Rhou ras homolog family member U (Synonyms: 2310026M05Rik, Arhu, CDC42L1, mG28K, WRCH-1, WRCH1) | |
Results | Reference |
1* | J:281551 Laurin M, Gomez NC, Levorse J, Sendoel A, Sribour M, Fuchs E, An RNAi screen unravels the complexities of Rho GTPase networks in skin morphogenesis. Elife. 2019 Sep 25;8:e50226 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Rhox6 reproductive homeobox 6 (Synonyms: Psx1) | |
Results | Reference |
1* | J:46103 Han YJ, Park AR, Sung DY, Chun JY, Psx, a novel murine homeobox gene expressed in placenta. Gene. 1998 Jan 30;207(2):159-66 |
1* | J:63116 Takasaki N, McIsaac R, Dean J, Gpbox (Psx2), a homeobox gene preferentially expressed in female germ cells at the onset of sexual dimorphism in mice. Dev Biol. 2000 Jul 1;223(1):181-93 |
Rhox9 reproductive homeobox 9 (Synonyms: 1600026O01Rik, Gpbox, Psx2) | |
Results | Reference |
1* | J:63116 Takasaki N, McIsaac R, Dean J, Gpbox (Psx2), a homeobox gene preferentially expressed in female germ cells at the onset of sexual dimorphism in mice. Dev Biol. 2000 Jul 1;223(1):181-93 |
Rhox10 reproductive homeobox 10 | |
Results | Reference |
1 | J:306228 Song HW, Dann CT, McCarrey JR, Meistrich ML, Cornwall GA, Wilkinson MF, Dynamic expression pattern and subcellular localization of the Rhox10 homeobox transcription factor during early germ cell development. Reproduction. 2012 May;143(5):611-24 |
Rian RNA imprinted and accumulated in nucleus (Synonyms: 5530401N18Rik, C130089L09Rik, Irm, Meg8) | |
Results | Reference |
1* | J:173506 Gu T, He H, Xing Y, Liu Q, Gu N, Kenkichi S, Jiang H, Wu Q, Expression of non-coding RNA AB063319 derived from Rian gene during mouse development. J Mol Histol. 2011 Apr;42(2):105-12 |
1 | J:218430 Kamimura S, Hatanaka Y, Hirasawa R, Matsumoto K, Oikawa M, Lee J, Matoba S, Mizutani E, Ogonuki N, Inoue K, Kohda T, Ishino F, Ogura A, Establishment of paternal genomic imprinting in mouse prospermatogonia analyzed by nuclear transfer. Biol Reprod. 2014 Nov;91(5):120 |
1* | J:299191 Kitazawa M, Hayashi S, Imamura M, Takeda S, Oishi Y, Kaneko-Ishino T, Ishino F, Deficiency and overexpression of Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Kagami-Ogata syndromes. Development. 2020 Sep 2;147(21):dev185918 |
1 | J:216177 Labialle S, Marty V, Bortolin-Cavaille ML, Hoareau-Osman M, Pradere JP, Valet P, Martin PG, Cavaille J, The miR-379/miR-410 cluster at the imprinted Dlk1-Dio3 domain controls neonatal metabolic adaptation. EMBO J. 2014 Oct 1;33(19):2216-30 |
1 | J:108133 Sekita Y, Wagatsuma H, Irie M, Kobayashi S, Kohda T, Matsuda J, Yokoyama M, Ogura A, Schuster-Gossler K, Gossler A, Ishino F, Kaneko-Ishino T, Aberrant regulation of imprinted gene expression in Gtl2lacZ mice. Cytogenet Genome Res. 2006;113(1-4):223-9 |
1* | J:166176 Zhou Y, Cheunsuchon P, Nakayama Y, Lawlor MW, Zhong Y, Rice KA, Zhang L, Zhang X, Gordon FE, Lidov HG, Bronson RT, Klibanski A, Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. Development. 2010 Aug;137(16):2643-52 |
Rictor RPTOR independent companion of MTOR, complex 2 (Synonyms: 4921505C17Rik, 6030405M08Rik, D530039E11Rik) | |
Results | Reference |
1 | J:119564 Shiota C, Woo JT, Lindner J, Shelton KD, Magnuson MA, Multiallelic disruption of the rictor gene in mice reveals that mTOR complex 2 is essential for fetal growth and viability. Dev Cell. 2006 Oct;11(4):583-9 |
Rims2 regulating synaptic membrane exocytosis 2 (Synonyms: 2810036I15Rik, mKIAA0751, RIM2, Syt3-rs) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1* | J:353281 Rybiczka-Tesulov M, Garritsen O, Veno MT, Wieg L, Dijk RV, Rahimi K, Gomes-Duarte A, Wit M, van de Haar LL, Michels L, van Kronenburg NCH, van der Meer C, Kjems J, Vangoor VR, Pasterkamp RJ, Circular RNAs regulate neuron size and migration of midbrain dopamine neurons during development. Nat Commun. 2024 Aug 8;15(1):6773 |
Ripk1 receptor (TNFRSF)-interacting serine-threonine kinase 1 (Synonyms: Rinp, Rip1) | |
Results | Reference |
1* | J:265712 Dziedzic SA, Su Z, Jean Barrett V, Najafov A, Mookhtiar AK, Amin P, Pan H, Sun L, Zhu H, Ma A, Abbott DW, Yuan J, ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC. Nat Cell Biol. 2018 Jan;20(1):58-68 |
1 | J:269295 Kang TB, Jeong JS, Yang SH, Kovalenko A, Wallach D, Caspase-8 deficiency in mouse embryos triggers chronic RIPK1-dependent activation of inflammatory genes, independently of RIPK3. Cell Death Differ. 2018 Jun;25(6):1107-1117 |
1 | J:311448 Liang W, Qi W, Geng Y, Wang L, Zhao J, Zhu K, Wu G, Zhang Z, Pan H, Qian L, Yuan J, Necroptosis activates UPR sensors without disrupting their binding with GRP78. Proc Natl Acad Sci U S A. 2021 Sep 28;118(39):e2110476118 |
Ripk3 receptor-interacting serine-threonine kinase 3 (Synonyms: 2610528K09Rik, Rip3) | |
Results | Reference |
1* | J:265712 Dziedzic SA, Su Z, Jean Barrett V, Najafov A, Mookhtiar AK, Amin P, Pan H, Sun L, Zhu H, Ma A, Abbott DW, Yuan J, ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC. Nat Cell Biol. 2018 Jan;20(1):58-68 |
1 | J:311448 Liang W, Qi W, Geng Y, Wang L, Zhao J, Zhu K, Wu G, Zhang Z, Pan H, Qian L, Yuan J, Necroptosis activates UPR sensors without disrupting their binding with GRP78. Proc Natl Acad Sci U S A. 2021 Sep 28;118(39):e2110476118 |
1 | J:285940 Newton K, Wickliffe KE, Maltzman A, Dugger DL, Reja R, Zhang Y, Roose-Girma M, Modrusan Z, Sagolla MS, Webster JD, Dixit VM, Activity of caspase-8 determines plasticity between cell death pathways. Nature. 2019 Nov;575(7784):679-682 |
Ripk4 receptor-interacting serine-threonine kinase 4 (Synonyms: ANKK2, Ankrd3, DIk, PKK, RIP4) | |
Results | Reference |
1 | J:283325 Oberbeck N, Pham VC, Webster JD, Reja R, Huang CS, Zhang Y, Roose-Girma M, Warming S, Li Q, Birnberg A, Wong W, Sandoval W, Komuves LG, Yu K, Dugger DL, Maltzman A, Newton K, Dixit VM, The RIPK4-IRF6 signalling axis safeguards epidermal differentiation and barrier function. Nature. 2019 Oct;574(7777):249-253 |
Ripply1 ripply transcriptional repressor 1 | |
Results | Reference |
1 | J:104947 Kawamura A, Koshida S, Hijikata H, Ohbayashi A, Kondoh H, Takada S, Groucho-associated transcriptional repressor ripply1 is required for proper transition from the presomitic mesoderm to somites. Dev Cell. 2005 Dec;9(6):735-44 |
Ripply2 ripply transcriptional repressor 2 (Synonyms: C030002E08Rik, LOC382089) | |
Results | Reference |
1 | J:104947 Kawamura A, Koshida S, Hijikata H, Ohbayashi A, Kondoh H, Takada S, Groucho-associated transcriptional repressor ripply1 is required for proper transition from the presomitic mesoderm to somites. Dev Cell. 2005 Dec;9(6):735-44 |
Rlbp1 retinaldehyde binding protein 1 (Synonyms: 3110056M11Rik, CRALBP) | |
Results | Reference |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1 | J:108702 Zhang CL, Zou Y, Yu RT, Gage FH, Evans RM, Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes Dev. 2006 May 15;20(10):1308-20 |
Rmdn3 regulator of microtubule dynamics 3 (Synonyms: 1200015F23Rik, Fam82a2) | |
Results | Reference |
3* | J:133715 Maerker D, Stenzinger A, Schreiner D, Tag C, Wimmer M, Expression of PTPIP51 during mouse eye development. Histochem Cell Biol. 2008 Mar;129(3):345-56 |
Rmst rhabdomyosarcoma 2 associated transcript (non-coding RNA) (Synonyms: C230053E11Rik, D930049J19Rik, Dmt2, Gm3515, M2, Ncrms) | |
Results | Reference |
1 | J:232481 Caronia-Brown G, Anderegg A, Awatramani R, Expression and functional analysis of the Wnt/beta-catenin induced mir-135a-2 locus in embryonic forebrain development. Neural Dev. 2016;11:9 |
1* | J:353281 Rybiczka-Tesulov M, Garritsen O, Veno MT, Wieg L, Dijk RV, Rahimi K, Gomes-Duarte A, Wit M, van de Haar LL, Michels L, van Kronenburg NCH, van der Meer C, Kjems J, Vangoor VR, Pasterkamp RJ, Circular RNAs regulate neuron size and migration of midbrain dopamine neurons during development. Nat Commun. 2024 Aug 8;15(1):6773 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Rn18s 18S ribosomal RNA | |
Results | Reference |
1 | J:316972 Mehta A, Dobersch S, Dammann RH, Bellusci S, Ilinskaya ON, Braun T, Barreto G, Validation of Tuba1a as appropriate internal control for normalization of gene expression analysis during mouse lung development. Int J Mol Sci. 2015 Feb 25;16(3):4492-511 |
Rncr4 retina expressed non-coding RNA 4 (Synonyms: Gm37046) | |
Results | Reference |
1* | J:258363 Ushakov K, Koffler-Brill T, Rom A, Perl K, Ulitsky I, Avraham KB, Genome-wide identification and expression profiling of long non-coding RNAs in auditory and vestibular systems. Sci Rep. 2017 Aug 17;7(1):8637 |
Rnd2 Rho family GTPase 2 (Synonyms: Arhn, Rohn) | |
Results | Reference |
1* | J:225235 Azzarelli R, Pacary E, Garg R, Garcez P, van den Berg D, Riou P, Ridley AJ, Friedel RH, Parsons M, Guillemot F, An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration. Nat Commun. 2014;5:3405 |
2 | J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5 |
1 | J:139577 Heng JI, Nguyen L, Castro DS, Zimmer C, Wildner H, Armant O, Skowronska-Krawczyk D, Bedogni F, Matter JM, Hevner R, Guillemot F, Neurogenin 2 controls cortical neuron migration through regulation of Rnd2. Nature. 2008 Sep 4;455(7209):114-8 |
1 | J:174732 Pacary E, Heng J, Azzarelli R, Riou P, Castro D, Lebel-Potter M, Parras C, Bell DM, Ridley AJ, Parsons M, Guillemot F, Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling. Neuron. 2011 Mar 24;69(6):1069-84 |
Rnd3 Rho family GTPase 3 (Synonyms: 2610017M01Rik, Arhe, Rhoe) | |
Results | Reference |
1* | J:225235 Azzarelli R, Pacary E, Garg R, Garcez P, van den Berg D, Riou P, Ridley AJ, Friedel RH, Parsons M, Guillemot F, An antagonistic interaction between PlexinB2 and Rnd3 controls RhoA activity and cortical neuron migration. Nat Commun. 2014;5:3405 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:338359 Kaur N, Han W, Li Z, Madrigal MP, Shim S, Pochareddy S, Gulden FO, Li M, Xu X, Xing X, Takeo Y, Li Z, Lu K, Imamura Kawasawa Y, Ballester-Lurbe B, Moreno-Bravo JA, Chedotal A, Terrado J, Perez-Roger I, Koleske AJ, Sestan N, Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold. Neuron. 2020 Sep 23;107(6):1197-1211.e9 |
1 | J:338454 Marfull-Oromi P, Fleitas C, Zammou B, Rocandio D, Ballester-Lurbe B, Terrado J, Perez-Roger I, Espinet C, Egea J, Genetic ablation of the Rho GTPase Rnd3 triggers developmental defects in internal capsule and the globus pallidus formation. J Neurochem. 2021 Jul;158(2):197-216 |
1 | J:174732 Pacary E, Heng J, Azzarelli R, Riou P, Castro D, Lebel-Potter M, Parras C, Bell DM, Ridley AJ, Parsons M, Guillemot F, Proneural transcription factors regulate different steps of cortical neuron migration through Rnd-mediated inhibition of RhoA signaling. Neuron. 2011 Mar 24;69(6):1069-84 |
1 | J:290493 Peng YR, James RE, Yan W, Kay JN, Kolodkin AL, Sanes JR, Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch. Neuron. 2020 Feb 5;105(3):464-474.e6 |
Rnf2 ring finger protein 2 (Synonyms: dinG, Ring1B) | |
Results | Reference |
1 | J:272608 Cohen I, Zhao D, Menon G, Nakayama M, Koseki H, Zheng D, Ezhkova E, PRC1 preserves epidermal tissue integrity independently of PRC2. Genes Dev. 2019 Jan 1;33(1-2):55-60 |
1 | J:230833 Mardaryev AN, Liu B, Rapisarda V, Poterlowicz K, Malashchuk I, Rudolf J, Sharov AA, Jahoda CA, Fessing MY, Benitah SA, Xu GL, Botchkarev VA, Cbx4 maintains the epithelial lineage identity and cell proliferation in the developing stratified epithelium. J Cell Biol. 2016 Jan 4;212(1):77-89 |
Rnf4 ring finger protein 4 (Synonyms: Gtrgeo8) | |
Results | Reference |
1 | J:40477 Baker RK, Haendel MA, Swanson BJ, Shambaugh JC, Micales BK, Lyons GE, In vitro preselection of gene-trapped embryonic stem cell clones for characterizing novel developmentally regulated genes in the mouse. Dev Biol. 1997 May 15;185(2):201-14 |
1* | J:45958 Chiariotti L, Benvenuto G, Fedele M, Santoro M, Simeone A, Fusco A, Bruni CB, Identification and characterization of a novel RING-finger gene (RNF4) mapping at 4p16.3. Genomics. 1998 Jan 15;47(2):258-65 |
1* | J:163687 Hu XV, Rodrigues TM, Tao H, Baker RK, Miraglia L, Orth AP, Lyons GE, Schultz PG, Wu X, Identification of RING finger protein 4 (RNF4) as a modulator of DNA demethylation through a functional genomics screen. Proc Natl Acad Sci U S A. 2010 Aug 24;107(34):15087-92 |
Rnf7 ring finger protein 7 (Synonyms: Rbx2, Sag) | |
Results | Reference |
2* | J:257927 Fairchild CL, Hino K, Han JS, Miltner AM, Peinado Allina G, Brown CE, Burns ME, La Torre A, Simo S, RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3):dev155283 |
1* | J:266809 Hino K, Simo S, Cooper JA, Comparative Analysis of cul5 and rbx2 Expression in the Developing and Adult Murine Brain and Their Essentiality During Mouse Embryogenesis. Dev Dyn. 2018 Nov;247(11):1227-1236 |
Rnf13 ring finger protein 13 (Synonyms: 2010001H16Rik, Rzf) | |
Results | Reference |
1* | J:148416 Bocock JP, Carmicle S, Chhotani S, Ruffolo MR, Chu H, Erickson AH, The PA-TM-RING protein RING finger protein 13 is an endosomal integral membrane E3 ubiquitin ligase whose RING finger domain is released to the cytoplasm by proteolysis. FEBS J. 2009 Apr;276(7):1860-77 |
Rnf20 ring finger protein 20 (Synonyms: 4833430L21Rik) | |
Results | Reference |
1* | J:363656 Barish S, Berg K, Drozd J, Berglund-Brown I, Khizir L, Wasson LK, Seidman CE, Seidman JG, Chen S, Brueckner M, The H2Bub1-deposition complex is required for human and mouse cardiogenesis. Development. 2023 Dec 1;150(23) |
1* | J:207461 Ishino Y, Hayashi Y, Naruse M, Tomita K, Sanbo M, Fuchigami T, Fujiki R, Hirose K, Toyooka Y, Fujimori T, Ikenaka K, Hitoshi S, Bre1a, a histone H2B ubiquitin ligase, regulates the cell cycle and differentiation of neural precursor cells. J Neurosci. 2014 Feb 19;34(8):3067-78 |
Rnf24 ring finger protein 24 (Synonyms: 2810473M14Rik, 4930505A13Rik, C86507, D2Ertd504e) | |
Results | Reference |
1* | J:333712 Liang J, Liang J, Tan Q, Wang Z, ELAC2 Functions as a Key Gene in the Early Development of Placental Formation Based on WGCNA. Cells. 2023 Feb 14;12(4) |
Rnf40 ring finger protein 40 (Synonyms: MGC:19037, mKIAA0661) | |
Results | Reference |
1* | J:363656 Barish S, Berg K, Drozd J, Berglund-Brown I, Khizir L, Wasson LK, Seidman CE, Seidman JG, Chen S, Brueckner M, The H2Bub1-deposition complex is required for human and mouse cardiogenesis. Development. 2023 Dec 1;150(23) |
Rnf111 ring finger 111 (Synonyms: Arkadia) | |
Results | Reference |
3 | J:196581 Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G, The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-beta signaling. Dev Biol. 2013 May 15;377(2):415-27 |
Rnf113a1 ring finger protein 113A1 (Synonyms: 2810428C21Rik) | |
Results | Reference |
3 | J:363296 Tsampoula M, Tarampoulous I, Manolakou T, Ninou E, Politis PK, The Neurodevelopmental Disorders Associated Gene Rnf113a Regulates Survival and Differentiation Properties of Neural Stem Cells. Stem Cells. 2022 Jul 27;40(7):678-690 |
Rnf113a2 ring finger protein 113A2 (Synonyms: 2310020H19Rik) | |
Results | Reference |
2 | J:363296 Tsampoula M, Tarampoulous I, Manolakou T, Ninou E, Politis PK, The Neurodevelopmental Disorders Associated Gene Rnf113a Regulates Survival and Differentiation Properties of Neural Stem Cells. Stem Cells. 2022 Jul 27;40(7):678-690 |
Rnf138 ring finger protein 138 (Synonyms: 2410015A17Rik, 2810480D20Rik, Trif-d) | |
Results | Reference |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Rnf152 ring finger protein 152 (Synonyms: A930029B02Rik) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Rnf180 ring finger protein 180 (Synonyms: 3110001E11Rik, Rines) | |
Results | Reference |
1* | J:141604 Ogawa M, Mizugishi K, Ishiguro A, Koyabu Y, Imai Y, Takahashi R, Mikoshiba K, Aruga J, Rines/RNF180, a novel RING finger gene-encoded product, is a membrane-bound ubiquitin ligase. Genes Cells. 2008 Apr;13(4):397-409 |
Rnf212 ring finger protein 212 (Synonyms: EG330157, repro57) | |
Results | Reference |
1 | J:361445 Ito M, Yun Y, Kulkarni DS, Lee S, Sandhu S, Nunez B, Hu L, Lee K, Lim N, Hirota RM, Prendergast R, Huang C, Huang I, Hunter N, Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis. Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2412961121 |
Rnf212b ring finger protein 212B (Synonyms: Gm10332, Gm30805) | |
Results | Reference |
1 | J:361445 Ito M, Yun Y, Kulkarni DS, Lee S, Sandhu S, Nunez B, Hu L, Lee K, Lim N, Hirota RM, Prendergast R, Huang C, Huang I, Hunter N, Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis. Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2412961121 |
Rnf220 ring finger protein 220 (Synonyms: 4931406I20Rik, 5730503K05Rik) | |
Results | Reference |
1* | J:286599 Song NN, Ma P, Zhang Q, Zhang L, Wang H, Zhang L, Zhu L, He CH, Mao B, Ding YQ, Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199 |
Rnmt RNA (guanine-7-) methyltransferase (Synonyms: 2610002P10Rik, mKIAA0398) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Rnu6 U6 small nuclear RNA | |
Results | Reference |
1* | J:313935 Fishman ES, Louie M, Miltner AM, Cheema SK, Wong J, Schlaeger NM, Moshiri A, Simo S, Tarantal AF, La Torre A, MicroRNA Signatures of the Developing Primate Fovea. Front Cell Dev Biol. 2021;9:654385 |
Robo1 roundabout guidance receptor 1 (Synonyms: DUTT1) | |
Results | Reference |
2* | J:82500 Anselmo MA, Dalvin S, Prodhan P, Komatsuzaki K, Aidlen JT, Schnitzer JJ, Wu JY, Bernard Kinane T, Slit and robo: expression patterns in lung development. Gene Expr Patterns. 2003 Mar;3(1):13-9 |
1 | J:315765 Borrell V, Cardenas A, Ciceri G, Galceran J, Flames N, Pla R, Nobrega-Pereira S, Garcia-Frigola C, Peregrin S, Zhao Z, Ma L, Tessier-Lavigne M, Marin O, Slit/Robo signaling modulates the proliferation of central nervous system progenitors. Neuron. 2012 Oct 18;76(2):338-52 |
1 | J:264379 Cardenas A, Villalba A, de Juan Romero C, Pico E, Kyrousi C, Tzika AC, Tessier-Lavigne M, Ma L, Drukker M, Cappello S, Borrell V, Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels. Cell. 2018 Jul 26;174(3):590-606.e21 |
2 | J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5 |
1 | J:126582 Cobos I, Borello U, Rubenstein JL, Dlx transcription factors promote migration through repression of axon and dendrite growth. Neuron. 2007 Jun 21;54(6):873-88 |
2 | J:119469 Fouquet C, Di Meglio T, Ma L, Kawasaki T, Long H, Hirata T, Tessier-Lavigne M, Chedotal A, Nguyen-Ba-Charvet KT, Robo1 and robo2 control the development of the lateral olfactory tract. J Neurosci. 2007 Mar 14;27(11):3037-45 |
1* | J:210150 Gonda Y, Andrews WD, Tabata H, Namba T, Parnavelas JG, Nakajima K, Kohsaka S, Hanashima C, Uchino S, Robo1 regulates the migration and laminar distribution of upper-layer pyramidal neurons of the cerebral cortex. Cereb Cortex. 2013 Jun;23(6):1495-508 |
1 | J:217604 Lavado A, Ware M, Pare J, Cao X, The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Development. 2014 Nov;141(21):4182-93 |
1* | J:71421 Loes S, Luukko K, Kvinnsland IH, Kettunen P, Slit1 is specifically expressed in the primary and secondary enamel knots during molar tooth cusp formation. Mech Dev. 2001 Sep;107(1-2):155-7 |
1 | J:120131 Lopez-Bendito G, Flames N, Ma L, Fouquet C, Di Meglio T, Chedotal A, Tessier-Lavigne M, Marin O, Robo1 and Robo2 cooperate to control the guidance of major axonal tracts in the mammalian forebrain. J Neurosci. 2007 Mar 28;27(13):3395-407 |
1* | J:114661 Lyu YL, Lin CP, Azarova AM, Cai L, Wang JC, Liu LF, Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Mol Cell Biol. 2006 Nov;26(21):7929-41 |
2* | J:134543 Nguyen-Ba-Charvet KT, Di Meglio T, Fouquet C, Chedotal A, Robos and slits control the pathfinding and targeting of mouse olfactory sensory axons. J Neurosci. 2008 Apr 16;28(16):4244-9 |
1 | J:154741 Prince JE, Cho JH, Dumontier E, Andrews W, Cutforth T, Tessier-Lavigne M, Parnavelas J, Cloutier JF, Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. J Neurosci. 2009 Nov 11;29(45):14211-22 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:110263 Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM, Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat Neurosci. 2006 Jun;9(6):787-97 |
2 | J:154456 Thompson H, Andrews W, Parnavelas JG, Erskine L, Robo2 is required for Slit-mediated intraretinal axon guidance. Dev Biol. 2009 Nov 15;335(2):418-26 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
1* | J:184936 Unni DK, Piper M, Moldrich RX, Gobius I, Liu S, Fothergill T, Donahoo AL, Baisden JM, Cooper HM, Richards LJ, Multiple Slits regulate the development of midline glial populations and the corpus callosum. Dev Biol. 2012 May 1;365(1):36-49 |
2 | J:199796 Wang SZ, Ibrahim LA, Kim YJ, Gibson DA, Leung HC, Yuan W, Zhang KK, Tao HW, Ma L, Zhang LI, Slit/Robo Signaling Mediates Spatial Positioning of Spiral Ganglion Neurons during Development of Cochlear Innervation. J Neurosci. 2013 Jul 24;33(30):12242-54 |
1 | J:282590 Wei S, Du H, Li Z, Tao G, Xu Z, Song X, Shang Z, Su Z, Chen H, Wen Y, Liu G, You Y, Zhang Z, Yang Z, Transcription factors Sp8 and Sp9 regulate the development of caudal ganglionic eminence-derived cortical interneurons. J Comp Neurol. 2019 Dec 1;527(17):2860-2874 |
1 | J:210623 Yeh ML, Gonda Y, Mommersteeg MT, Barber M, Ypsilanti AR, Hanashima C, Parnavelas JG, Andrews WD, Robo1 modulates proliferation and neurogenesis in the developing neocortex. J Neurosci. 2014 Apr 16;34(16):5717-31 |
Robo2 roundabout guidance receptor 2 (Synonyms: 2600013A04Rik, 9430089E08Rik, D230004I22Rik, mKIAA1568) | |
Results | Reference |
2* | J:82500 Anselmo MA, Dalvin S, Prodhan P, Komatsuzaki K, Aidlen JT, Schnitzer JJ, Wu JY, Bernard Kinane T, Slit and robo: expression patterns in lung development. Gene Expr Patterns. 2003 Mar;3(1):13-9 |
1 | J:315765 Borrell V, Cardenas A, Ciceri G, Galceran J, Flames N, Pla R, Nobrega-Pereira S, Garcia-Frigola C, Peregrin S, Zhao Z, Ma L, Tessier-Lavigne M, Marin O, Slit/Robo signaling modulates the proliferation of central nervous system progenitors. Neuron. 2012 Oct 18;76(2):338-52 |
1 | J:264379 Cardenas A, Villalba A, de Juan Romero C, Pico E, Kyrousi C, Tzika AC, Tessier-Lavigne M, Ma L, Drukker M, Cappello S, Borrell V, Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels. Cell. 2018 Jul 26;174(3):590-606.e21 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:226607 Clegg JM, Li Z, Molinek M, Caballero IM, Manuel MN, Price DJ, Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons. Neural Dev. 2015;10(1):26 |
2 | J:196018 Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W, Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell Rep. 2012 Jul 26;2(1):52-61 |
2 | J:119469 Fouquet C, Di Meglio T, Ma L, Kawasaki T, Long H, Hirata T, Tessier-Lavigne M, Chedotal A, Nguyen-Ba-Charvet KT, Robo1 and robo2 control the development of the lateral olfactory tract. J Neurosci. 2007 Mar 14;27(11):3037-45 |
1 | J:90281 Greenberg JM, Thompson FY, Brooks SK, Shannon JM, Akeson AL, Slit and robo expression in the developing mouse lung. Dev Dyn. 2004 Jun;230(2):350-60 |
1 | J:94593 Inaki K, Nishimura S, Nakashiba T, Itohara S, Yoshihara Y, Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules. J Comp Neurol. 2004 Nov 15;479(3):243-56 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:71421 Loes S, Luukko K, Kvinnsland IH, Kettunen P, Slit1 is specifically expressed in the primary and secondary enamel knots during molar tooth cusp formation. Mech Dev. 2001 Sep;107(1-2):155-7 |
1 | J:120131 Lopez-Bendito G, Flames N, Ma L, Fouquet C, Di Meglio T, Chedotal A, Tessier-Lavigne M, Marin O, Robo1 and Robo2 cooperate to control the guidance of major axonal tracts in the mammalian forebrain. J Neurosci. 2007 Mar 28;27(13):3395-407 |
1* | J:134543 Nguyen-Ba-Charvet KT, Di Meglio T, Fouquet C, Chedotal A, Robos and slits control the pathfinding and targeting of mouse olfactory sensory axons. J Neurosci. 2008 Apr 16;28(16):4244-9 |
1 | J:154741 Prince JE, Cho JH, Dumontier E, Andrews W, Cutforth T, Tessier-Lavigne M, Parnavelas J, Cloutier JF, Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. J Neurosci. 2009 Nov 11;29(45):14211-22 |
2 | J:154456 Thompson H, Andrews W, Parnavelas JG, Erskine L, Robo2 is required for Slit-mediated intraretinal axon guidance. Dev Biol. 2009 Nov 15;335(2):418-26 |
1* | J:104160 Tole S, Gutin G, Bhatnagar L, Remedios R, Hebert JM, Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev Biol. 2006 Jan 1;289(1):141-51 |
1* | J:184936 Unni DK, Piper M, Moldrich RX, Gobius I, Liu S, Fothergill T, Donahoo AL, Baisden JM, Cooper HM, Richards LJ, Multiple Slits regulate the development of midline glial populations and the corpus callosum. Dev Biol. 2012 May 1;365(1):36-49 |
2 | J:199796 Wang SZ, Ibrahim LA, Kim YJ, Gibson DA, Leung HC, Yuan W, Zhang KK, Tao HW, Ma L, Zhang LI, Slit/Robo Signaling Mediates Spatial Positioning of Spiral Ganglion Neurons during Development of Cochlear Innervation. J Neurosci. 2013 Jul 24;33(30):12242-54 |
1 | J:324235 Yu M, Tan L, Li Y, Chen J, Zhai Y, Rao J, Fang X, Wu X, Xu H, Shen Q, Intrauterine low-protein diet aggravates developmental abnormalities of the urinary system via the Akt/Creb3 pathway in Robo2 mutant mice. Am J Physiol Renal Physiol. 2020 Jan 1;318(1):F43-F52 |
Robo3 roundabout guidance receptor 3 (Synonyms: Rbig1, Rig-1, Rig1, Robo3a, Robo3b) | |
Results | Reference |
2* | J:308673 Company V, Andreu-Cervera A, Madrigal MP, Andres B, Almagro-Garcia F, Chedotal A, Lopez-Bendito G, Martinez S, Echevarria D, Moreno-Bravo JA, Puelles E, Netrin 1-Mediated Role of the Substantia Nigra Pars Compacta and Ventral Tegmental Area in the Guidance of the Medial Habenular Axons. Front Cell Dev Biol. 2021;9:682067 |
3* | J:278498 Friocourt F, Kozulin P, Belle M, Suarez R, Di-Poi N, Richards LJ, Giacobini P, Chedotal A, Shared and differential features of Robo3 expression pattern in amniotes. J Comp Neurol. 2019 Aug 15;527(12):2009-2029 |
2 | J:91469 Marillat V, Sabatier C, Failli V, Matsunaga E, Sotelo C, Tessier-Lavigne M, Chedotal A, The slit receptor Rig-1/Robo3 controls midline crossing by hindbrain precerebellar neurons and axons. Neuron. 2004 Jul 8;43(1):69-79 |
2 | J:348685 Masuda A, Nishida K, Ajima R, Saga Y, Bakhtan M, Klar A, Hirata T, Zhu Y, A global gene regulatory program and its region-specific regulator partition neurons into commissural and ipsilateral projection types. Sci Adv. 2024 May 24;10(21):eadk2149 |
1 | J:154741 Prince JE, Cho JH, Dumontier E, Andrews W, Cutforth T, Tessier-Lavigne M, Parnavelas J, Cloutier JF, Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. J Neurosci. 2009 Nov 11;29(45):14211-22 |
1 | J:215618 Schmidt ER, Brignani S, Adolfs Y, Lemstra S, Demmers J, Vidaki M, Donahoo AL, Lillevali K, Vasar E, Richards LJ, Karagogeos D, Kolk SM, Pasterkamp RJ, Subdomain-mediated axon-axon signaling and chemoattraction cooperate to regulate afferent innervation of the lateral habenula. Neuron. 2014 Jul 16;83(2):372-87 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:154456 Thompson H, Andrews W, Parnavelas JG, Erskine L, Robo2 is required for Slit-mediated intraretinal axon guidance. Dev Biol. 2009 Nov 15;335(2):418-26 |
1 | J:210623 Yeh ML, Gonda Y, Mommersteeg MT, Barber M, Ypsilanti AR, Hanashima C, Parnavelas JG, Andrews WD, Robo1 modulates proliferation and neurogenesis in the developing neocortex. J Neurosci. 2014 Apr 16;34(16):5717-31 |
1 | J:294199 Zhu Y, Hirata T, Mackay F, Murakami F, Chemokine receptor CXCR7 non-cell-autonomously controls pontine neuronal migration and nucleus formation. Sci Rep. 2020 Jul 16;10(1):11830 |
Robo4 roundabout guidance receptor 4 (Synonyms: 1200012D01Rik, Magic roundabout) | |
Results | Reference |
1 | J:154456 Thompson H, Andrews W, Parnavelas JG, Erskine L, Robo2 is required for Slit-mediated intraretinal axon guidance. Dev Biol. 2009 Nov 15;335(2):418-26 |
Rock1 Rho-associated coiled-coil containing protein kinase 1 (Synonyms: 1110055K06Rik, Rock-I) | |
Results | Reference |
1 | J:167714 Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, Chen H, Haneline LS, Chan RJ, Schwartz RJ, Field LJ, Atkinson SJ, Shou W, Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development. 2011 Jan;138(2):303-15 |
Rock2 Rho-associated coiled-coil containing protein kinase 2 (Synonyms: B230113H15Rik, Rho-kinase, Rock2m, Rock-II, ROKalpha) | |
Results | Reference |
1 | J:167714 Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, Chen H, Haneline LS, Chan RJ, Schwartz RJ, Field LJ, Atkinson SJ, Shou W, Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development. 2011 Jan;138(2):303-15 |
Rogdi rogdi homolog (Synonyms: 0610011C19Rik, Lzf) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:344072 Jimenez-Armijo A, Morkmued S, Ahumada JT, Kharouf N, de Feraudy Y, Gogl G, Riet F, Niederreither K, Laporte J, Birling MC, Selloum M, Herault Y, Hernandez M, Bloch-Zupan A, The Rogdi knockout mouse is a model for Kohlschutter-Tonz syndrome. Sci Rep. 2024 Jan 3;14(1):445 |
Rom1 rod outer segment membrane protein 1 (Synonyms: M101156, Rgsc1156, Rom-1, Tspan23) | |
Results | Reference |
1 | J:285747 Liu S, Liu X, Li S, Huang X, Qian H, Jin K, Xiang M, Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5016-5027 |
Ror2 receptor tyrosine kinase-like orphan receptor 2 (Synonyms: Ntrkr2) | |
Results | Reference |
1 | J:313969 Alcantara MC, Suzuki K, Acebedo AR, Sakamoto Y, Nishita M, Minami Y, Kikuchi A, Yamada G, Stage-dependent function of Wnt5a during male external genitalia development. Congenit Anom (Kyoto). 2021 Nov;61(6):212-219 |
1* | J:156970 Mikels A, Minami Y, Nusse R, Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling. J Biol Chem. 2009 Oct 30;284(44):30167-76 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
1* | J:88955 Schwabe GC, Trepczik B, Suring K, Brieske N, Tucker AS, Sharpe PT, Minami Y, Mundlos S, Ror2 knockout mouse as a model for the developmental pathology of autosomal recessive Robinow syndrome. Dev Dyn. 2004 Feb;229(2):400-10 |
1* | J:297051 Wang S, Roy JP, Tomlinson AJ, Wang EB, Tsai YH, Cameron L, Underwood J, Spence JR, Walton KD, Stacker SA, Gumucio DL, Lechler T, RYK-mediated filopodial pathfinding facilitates midgut elongation. Development. 2020 Oct 27;147(20):dev195388 |
1 | J:156943 Yamada M, Udagawa J, Matsumoto A, Hashimoto R, Hatta T, Nishita M, Minami Y, Otani H, Ror2 is required for midgut elongation during mouse development. Dev Dyn. 2010 Jan 8;239(3):941-953 |
Rora RAR-related orphan receptor alpha (Synonyms: 9530021D13Rik, Nr1f1, tmgc26) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
1 | J:331478 Monko T, Rebertus J, Stolley J, Salton SR, Nakagawa Y, Thalamocortical axons regulate neurogenesis and laminar fates in the early sensory cortex. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2201355119 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:147427 Vue TY, Bluske K, Alishahi A, Yang LL, Koyano-Nakagawa N, Novitch B, Nakagawa Y, Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice. J Neurosci. 2009 Apr 8;29(14):4484-97 |
Rorb RAR-related orphan receptor beta (Synonyms: hstp, MGC:38728, Nr1f2, Rorbeta, RZR-beta) | |
Results | Reference |
1 | J:127387 Armentano M, Chou SJ, Tomassy GS, Leingartner A, O'Leary DD, Studer M, COUP-TFI regulates the balance of cortical patterning between frontal/motor and sensory areas. Nat Neurosci. 2007 Oct;10(10):1277-86 |
1* | J:184357 Dye CA, El Shawa H, Huffman KJ, A lifespan analysis of intraneocortical connections and gene expression in the mouse I. Cereb Cortex. 2011 Jun;21(6):1311-30 |
1 | J:331478 Monko T, Rebertus J, Stolley J, Salton SR, Nakagawa Y, Thalamocortical axons regulate neurogenesis and laminar fates in the early sensory cortex. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2201355119 |
1* | J:85879 Nakagawa Y, O'Leary DD, Dynamic patterned expression of orphan nuclear receptor genes RORalpha and RORbeta in developing mouse forebrain. Dev Neurosci. 2003 Mar-Aug;25(2-4):234-44 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1* | J:263835 Newman EA, Kim DW, Wan J, Wang J, Qian J, Blackshaw S, Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes. Dev Biol. 2018 Jul 15;439(2):102-111 |
1* | J:231073 Oishi K, Aramaki M, Nakajima K, Mutually repressive interaction between Brn1/2 and Rorb contributes to the establishment of neocortical layer 2/3 and layer 4. Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3371-6 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:184434 Xiang C, Baubet V, Pal S, Holderbaum L, Tatard V, Jiang P, Davuluri RV, Dahmane N, RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion. Cell Death Differ. 2012 Apr;19(4):692-702 |
Rorc RAR-related orphan receptor gamma (Synonyms: RORgamma, Thor, thymus orphan receptor) | |
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1 | J:87395 Eberl G, Marmon S, Sunshine MJ, Rennert PD, Choi Y, Littman DR, An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat Immunol. 2004 Jan;5(1):64-73 |
1 | J:331478 Monko T, Rebertus J, Stolley J, Salton SR, Nakagawa Y, Thalamocortical axons regulate neurogenesis and laminar fates in the early sensory cortex. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2201355119 |
1 | J:142686 Vondenhoff MF, van de Pavert SA, Dillard ME, Greuter M, Goverse G, Oliver G, Mebius RE, Lymph sacs are not required for the initiation of lymph node formation. Development. 2009 Jan;136(1):29-34 |
Ros1 Ros1 proto-oncogene (Synonyms: c-ros, Ros-1) | |
Results | Reference |
1* | J:1111 Tessarollo L, Nagarajan L, Parada LF, c-ros: the vertebrate homolog of the sevenless tyrosine kinase receptor is tightly regulated during organogenesis in mouse embryonic development. Development. 1992 May;115(1):11-20 |
Rpa1 replication protein A1 (Synonyms: 5031405K23Rik, 70kDa, RF-A, Rpa, RP-A) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
1 | J:173089 Daniel K, Lange J, Hached K, Fu J, Anastassiadis K, Roig I, Cooke HJ, Stewart AF, Wassmann K, Jasin M, Keeney S, Toth A, Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1. Nat Cell Biol. 2011 May;13(5):599-610 |
1 | J:211663 Fukuda T, Fukuda N, Agostinho A, Hernandez-Hernandez A, Kouznetsova A, Hoog C, STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. EMBO J. 2014 Jun 2;33(11):1243-55 |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
1 | J:281207 Vazquez BN, Blengini CS, Hernandez Y, Serrano L, Schindler K, SIRT7 promotes chromosome synapsis during prophase I of female meiosis. Chromosoma. 2019 Sep;128(3):369-383 |
Rpa2 replication protein A2 (Synonyms: 30-kDa protein, Rf-A2, RPA34) | |
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1 | J:325094 Guan Y, Lin H, Leu NA, Ruthel G, Fuchs SY, Busino L, Luo M, Wang PJ, SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination. Nucleic Acids Res. 2022 May 20;50(9):5129-5144 |
Rpe65 retinal pigment epithelium 65 (Synonyms: A930029L06Rik, Mord1, rd12) | |
Results | Reference |
1 | J:317613 Patnaik SR, Kretschmer V, Brucker L, Schneider S, Volz AK, Oancea-Castillo LDR, May-Simera HL, Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation. Cell Mol Life Sci. 2019 Feb;76(4):757-775 |
Rph3a rabphilin 3A (Synonyms: 2900002P20Rik, Doc2 family) | |
Results | Reference |
1 | J:143462 Liu Z, Li H, Hu X, Yu L, Liu H, Han R, Colella R, Mower GD, Chen Y, Qiu M, Control of precerebellar neuron development by Olig3 bHLH transcription factor. J Neurosci. 2008 Oct 1;28(40):10124-33 |
1 | J:283382 Qin L, Ahn KJ, Wine Lee L, de Charleroy C Jr, Crenshaw EB 3rd, Analyses with double knockouts of the Bmpr1a and Bmpr1b genes demonstrate that BMP signaling is involved in the formation of precerebellar mossy fiber nuclei derived from the rhombic lip. PLoS One. 2019;14(12):e0226602 |
Rpl6 ribosomal protein L6 (Synonyms: Taxreb107) | |
Results | Reference |
1 | J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134 |
Rpl7 ribosomal protein L7 (Synonyms: Rpl7a, Surf-3) | |
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1* | J:26722 Southard JN, Barrett BA, Bikbulatova L, Ilkbahar Y, Wu K, Talamantes F, Growth hormone (GH) receptor and GH-binding protein messenger ribonucleic acids with alternative 5'-untranslated regions are differentially expressed in mouse liver and placenta. Endocrinology. 1995 Jul;136(7):2913-21 |
Rpl8 ribosomal protein L8 | |
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1 | J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134 |
Rpl10 ribosomal protein L10 (Synonyms: 24.6kDa protein, D0HXS648, DXHXS648, DXHXS648E, QM16) | |
Results | Reference |
1* | J:54774 Mills AA, Mills MJ, Gardiner DM, Bryant SV, Stanbridge EJ, Analysis of the pattern of QM expression during mouse development. Differentiation. 1999 Mar;64(3):161-71 |
Rpl12 ribosomal protein L12 | |
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2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Rpl19 ribosomal protein L19 | |
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1 | J:166789 Dong Y, Sui L, Yamaguchi F, Kamitori K, Hirata Y, Hossain MA, Suzuki A, Holley MC, Tokuda M, Phosphatase and tensin homolog deleted on chromosome 10 regulates sensory cell proliferation and differentiation of hair bundles in the mammalian cochlea. Neuroscience. 2010 Nov 10;170(4):1304-13 |
Rpl23 ribosomal protein L23 (Synonyms: 2810009A01Rik) | |
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1* | J:66696 Kleiter N, Artner I, Copeland NG, Gilbert DJ, Jenkins NA, Kratochwil K, Genomic organization and chromosome location of the murine Rpl23 gene. Cytogenet Cell Genet. 2000;90(3-4):227-30 |
Rpl27a ribosomal protein L27A (Synonyms: L27', L27A, ribosomal protein L29 homolog (yeast)) | |
Results | Reference |
1 | J:71272 Michalik L, Desvergne B, Tan NS, Basu-Modak S, Escher P, Rieusset J, Peters JM, Kaya G, Gonzalez FJ, Zakany J, Metzger D, Chambon P, Duboule D, Wahli W, Impaired skin wound healing in peroxisome proliferator-activated receptor (PPAR)alpha and PPARbeta mutant mice. J Cell Biol. 2001 Aug 20;154(4):799-814 |
Rplp0 ribosomal protein lateral stalk subunit P0 (Synonyms: 36B4, Arbp) | |
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1* | J:267655 Marjonen H, Toivonen M, Lahti L, Kaminen-Ahola N, Early prenatal alcohol exposure alters imprinted gene expression in placenta and embryo in a mouse model. PLoS One. 2018;13(5):e0197461 |
1 | J:139012 Mohri Y, Kato S, Umezawa A, Okuyama R, Nishimori K, Impaired hair placode formation with reduced expression of hair follicle-related genes in mice lacking Lgr4. Dev Dyn. 2008 Aug;237(8):2235-42 |
1 | J:201076 Okano T, Kelley MW, Expression of insulin-like growth factor binding proteins during mouse cochlear development. Dev Dyn. 2013 Oct;242(10):1210-21 |
Rps3 ribosomal protein S3 (Synonyms: D7Ertd795e) | |
Results | Reference |
1 | J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134 |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Rps6 ribosomal protein S6 (Synonyms: S6R) | |
Results | Reference |
1* | J:332849 Baskaran P, Mihaylov SR, Vinsland E, Shah K, Granat L, Ultanir SK, Tee AR, Murn J, Bateman JM, Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis. J Biol Chem. 2023 Jan;299(1):102788 |
1* | J:213870 Chen J, Long F, mTORC1 signaling controls mammalian skeletal growth through stimulation of protein synthesis. Development. 2014 Jul;141(14):2848-54 |
1 | J:242729 Ding X, Bloch W, Iden S, Ruegg MA, Hall MN, Leptin M, Partridge L, Eming SA, mTORC1 and mTORC2 regulate skin morphogenesis and epidermal barrier formation. Nat Commun. 2016 Oct 27;7:13226 |
1 | J:239666 Hagglund AC, Jones I, Carlsson L, A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development. Dis Model Mech. 2017 Mar 01;10(3):245-257 |
1 | J:279675 Jones I, Hagglund AC, Carlsson L, Reduced mTORC1-signalling in retinal progenitor cells leads to visual pathway dysfunction. Biol Open. 2019 Aug 1;8(8):bio044370 |
1 | J:177840 Magri L, Cambiaghi M, Cominelli M, Alfaro-Cervello C, Cursi M, Pala M, Bulfone A, Garcia-Verdugo JM, Leocani L, Minicucci F, Poliani PL, Galli R, Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions. Cell Stem Cell. 2011 Nov 4;9(5):447-62 |
2 | J:232899 Moon UY, Park JY, Park R, Cho JY, Hughes LJ, McKenna J 3rd, Goetzl L, Cho SH, Crino PB, Gambello MJ, Kim S, Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex. Cell Rep. 2015 Aug 11;12(6):965-78 |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
1 | J:355222 Nord C, Jones I, Garcia-Maestre M, Hagglund AC, Carlsson L, Reduced mTORC1-signaling in progenitor cells leads to retinal lamination deficits. Dev Dyn. 2024 Oct;253(10):922-939 |
1* | J:319569 Ohira T, Spear D, Azimi N, Andreeva V, Yelick PC, Chemerin-ChemR23 signaling in tooth development. J Dent Res. 2012 Dec;91(12):1147-53 |
2 | J:326480 Terry BK, Park R, Cho SH, Crino PB, Kim S, Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex. Hum Mol Genet. 2022 Jun 22;31(12):1979-1996 |
2 | J:225743 Um SH, Sticker-Jantscheff M, Chau GC, Vintersten K, Mueller M, Gangloff YG, Adams RH, Spetz JF, Elghazi L, Pfluger PT, Pende M, Bernal-Mizrachi E, Tauler A, Tschop MH, Thomas G, Kozma SC, S6K1 controls pancreatic beta cell size independently of intrauterine growth restriction. J Clin Invest. 2015 Jul 1;125(7):2736-47 |
1 | J:309451 Vinsland E, Baskaran P, Mihaylov SR, Hobbs C, Wood H, Bouybayoune I, Shah K, Houart C, Tee AR, Murn J, Fernandes C, Bateman JM, The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021 Aug 11;11(1):16299 |
1 | J:168571 Zou J, Zhou L, Du XX, Ji Y, Xu J, Tian J, Jiang W, Zou Y, Yu S, Gan L, Luo M, Yang Q, Cui Y, Yang W, Xia X, Chen M, Zhao X, Shen Y, Chen PY, Worley PF, Xiao B, Rheb1 is required for mTORC1 and myelination in postnatal brain development. Dev Cell. 2011 Jan 18;20(1):97-108 |
Rps6ka1 ribosomal protein S6 kinase polypeptide 1 (Synonyms: Rsk1) | |
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1* | J:211945 Laugel-Haushalter V, Paschaki M, Marangoni P, Pilgram C, Langer A, Kuntz T, Demassue J, Morkmued S, Choquet P, Constantinesco A, Bornert F, Schmittbuhl M, Pannetier S, Viriot L, Hanauer A, Dolle P, Bloch-Zupan A, RSK2 is a modulator of craniofacial development. PLoS One. 2014;9(1):e84343 |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
2 | J:79975 Zeniou M, Ding T, Trivier E, Hanauer A, Expression analysis of RSK gene family members: the RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and learning. Hum Mol Genet. 2002 Nov 1;11(23):2929-40 |
Rps6ka2 ribosomal protein S6 kinase, polypeptide 2 (Synonyms: 90kDa, D17Wsu134e, p90rsk, pp90rsk, Rps6ka-rs1, Rsk3) | |
Results | Reference |
1* | J:211945 Laugel-Haushalter V, Paschaki M, Marangoni P, Pilgram C, Langer A, Kuntz T, Demassue J, Morkmued S, Choquet P, Constantinesco A, Bornert F, Schmittbuhl M, Pannetier S, Viriot L, Hanauer A, Dolle P, Bloch-Zupan A, RSK2 is a modulator of craniofacial development. PLoS One. 2014;9(1):e84343 |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
1 | J:79975 Zeniou M, Ding T, Trivier E, Hanauer A, Expression analysis of RSK gene family members: the RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and learning. Hum Mol Genet. 2002 Nov 1;11(23):2929-40 |
Rps6ka3 ribosomal protein S6 kinase polypeptide 3 (Synonyms: Rsk2) | |
Results | Reference |
1* | J:211945 Laugel-Haushalter V, Paschaki M, Marangoni P, Pilgram C, Langer A, Kuntz T, Demassue J, Morkmued S, Choquet P, Constantinesco A, Bornert F, Schmittbuhl M, Pannetier S, Viriot L, Hanauer A, Dolle P, Bloch-Zupan A, RSK2 is a modulator of craniofacial development. PLoS One. 2014;9(1):e84343 |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
1 | J:79975 Zeniou M, Ding T, Trivier E, Hanauer A, Expression analysis of RSK gene family members: the RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and learning. Hum Mol Genet. 2002 Nov 1;11(23):2929-40 |
Rps6ka6 ribosomal protein S6 kinase polypeptide 6 (Synonyms: 2610524K04Rik, RSK4) | |
Results | Reference |
1* | J:211945 Laugel-Haushalter V, Paschaki M, Marangoni P, Pilgram C, Langer A, Kuntz T, Demassue J, Morkmued S, Choquet P, Constantinesco A, Bornert F, Schmittbuhl M, Pannetier S, Viriot L, Hanauer A, Dolle P, Bloch-Zupan A, RSK2 is a modulator of craniofacial development. PLoS One. 2014;9(1):e84343 |
Rps6kb1 ribosomal protein S6 kinase, polypeptide 1 (Synonyms: 2610318I15Rik, p70/85s6k, p70s6k, p70S6K1, S6K1) | |
Results | Reference |
1 | J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410 |
1 | J:208719 Tsai MJ, Yang-Yen HF, Chiang MK, Wang MJ, Wu SS, Chen SH, TCTP is essential for beta-cell proliferation and mass expansion during development and beta-cell adaptation in response to insulin resistance. Endocrinology. 2014 Feb;155(2):392-404 |
1 | J:225743 Um SH, Sticker-Jantscheff M, Chau GC, Vintersten K, Mueller M, Gangloff YG, Adams RH, Spetz JF, Elghazi L, Pfluger PT, Pende M, Bernal-Mizrachi E, Tauler A, Tschop MH, Thomas G, Kozma SC, S6K1 controls pancreatic beta cell size independently of intrauterine growth restriction. J Clin Invest. 2015 Jul 1;125(7):2736-47 |
Rps7 ribosomal protein S7 (Synonyms: Mtu, S7) | |
Results | Reference |
1 | J:195156 Watkins-Chow DE, Cooke J, Pidsley R, Edwards A, Slotkin R, Leeds KE, Mullen R, Baxter LL, Campbell TG, Salzer MC, Biondini L, Gibney G, Phan Dinh Tuy F, Chelly J, Morris HD, Riegler J, Lythgoe MF, Arkell RM, Loreni F, Flint J, Pavan WJ, Keays DA, Mutation of the diamond-blackfan anemia gene Rps7 in mouse results in morphological and neuroanatomical phenotypes. PLoS Genet. 2013 Jan;9(1):e1003094 |
Rps10 ribosomal protein S10 (Synonyms: 2210402A09Rik) | |
Results | Reference |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Rps13 ribosomal protein S13 (Synonyms: 2700063M04Rik) | |
Results | Reference |
1 | J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134 |
Rps14 ribosomal protein S14 (Synonyms: 2600014J02Rik) | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Rps26 ribosomal protein S26 | |
Results | Reference |
1* | J:350102 Yu Y, Zuo X, He M, Gao J, Fu Y, Qin C, Meng L, Wang W, Song Y, Cheng Y, Zhou F, Chen G, Zheng X, Wang X, Liang B, Zhu Z, Fu X, Sheng Y, Hao J, Liu Z, Yan H, Mangold E, Ruczinski I, Liu J, Marazita ML, Ludwig KU, Beaty TH, Zhang X, Sun L, Bian Z, Genome-wide analyses of non-syndromic cleft lip with palate identify 14 novel loci and genetic heterogeneity. Nat Commun. 2017 Feb 24;8:14364 |
Rps27 ribosomal protein S27 (Synonyms: 3200001M24Rik) | |
Results | Reference |
1 | J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39 |
1 | J:206588 Mardaryev AN, Gdula MR, Yarker JL, Emelianov VN, Poterlowicz K, Sharov AA, Sharova TY, Scarpa JA, Chambon P, Botchkarev VA, Fessing MY, p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells. Development. 2014 Jan;141(1):101-11 |
Rpsa ribosomal protein SA (Synonyms: 67lr, Lamr, Lamr1, Lamrl1, P40-3, P40-8) | |
Results | Reference |
1 | J:332234 Harada M, Akita K, Mouse vaginal development with lateral enlargement at late embryonic stages and caudal elongation after birth. Congenit Anom (Kyoto). 2022 Dec 14; |
1 | J:222425 Harada M, Omori A, Nakahara C, Nakagata N, Akita K, Yamada G, Tissue-specific roles of FGF signaling in external genitalia development. Dev Dyn. 2015 Jun;244(6):759-73 |
1 | J:41054 Rabacchi SA, Neve RL, Drager UC, A positional marker for the dorsal embryonic retina is homologous to the high-affinity laminin receptor. Development. 1990 Jul;109(3):521-31 |
Rptn repetin | |
Results | Reference |
1* | J:198837 Cui CY, Klar J, Georgii-Heming P, Frojmark AS, Baig SM, Schlessinger D, Dahl N, Frizzled6 deficiency disrupts the differentiation process of nail development. J Invest Dermatol. 2013 Aug;133(8):1990-7 |
1 | J:114626 Yu Z, Lin KK, Bhandari A, Spencer JA, Xu X, Wang N, Lu Z, Gill GN, Roop DR, Wertz P, Andersen B, The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Dev Biol. 2006 Nov 1;299(1):122-36 |
Rptor regulatory associated protein of MTOR, complex 1 (Synonyms: 4932417H02Rik, mKIAA1303, Rap, raptor) | |
Results | Reference |
1 | J:309451 Vinsland E, Baskaran P, Mihaylov SR, Hobbs C, Wood H, Bouybayoune I, Shah K, Houart C, Tee AR, Murn J, Fernandes C, Bateman JM, The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021 Aug 11;11(1):16299 |
Rras related RAS viral (r-ras) oncogene (Synonyms: Rras1) | |
Results | Reference |
1 | J:34617 Stubbs L, Carver EA, Shannon ME, Kim J, Geisler J, Generoso EE, Stanford BG, Dunn WC, Mohrenweiser H, Zimmermann W, Watt SM, Ashworth LK, Detailed comparative map of human chromosome 19q and related regions of the mouse genome. Genomics. 1996 Aug 1;35(3):499-508 |
Rras2 related RAS viral (r-ras) oncogene 2 (Synonyms: 2610016H24Rik, TC21) | |
Results | Reference |
1 | J:197776 Larive RM, Abad A, Cardaba CM, Hernandez T, Canamero M, de Alava E, Santos E, Alarcon B, Bustelo XR, The Ras-like protein R-Ras2/TC21 is important for proper mammary gland development. Mol Biol Cell. 2012 Jun;23(12):2373-87 |
Rrm1 ribonucleotide reductase M1 (Synonyms: RnrM1) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
Rrm2 ribonucleotide reductase M2 (Synonyms: R2) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Rsad2 radical S-adenosyl methionine domain containing 2 (Synonyms: 2510004L01Rik, cig5, Vig1, viperin) | |
Results | Reference |
1 | J:288683 Gacem N, Kavo A, Zerad L, Richard L, Mathis S, Kapur RP, Parisot M, Amiel J, Dufour S, de la Grange P, Pingault V, Vallat JM, Bondurand N, ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. Nat Commun. 2020 Jan 10;11(1):198 |
Rsl1d1 ribosomal L1 domain containing 1 (Synonyms: 2410005K20Rik) | |
Results | Reference |
1* | J:117454 Meng L, Yasumoto H, Tsai RY, Multiple controls regulate nucleostemin partitioning between nucleolus and nucleoplasm. J Cell Sci. 2006 Dec 15;119(Pt 24):5124-36 |
Rsph4a radial spoke head 4 homolog A (Chlamydomonas) (Synonyms: Rshl3) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Rsph9 radial spoke head 9 homolog (Chlamydomonas) (Synonyms: 1700027N10Rik) | |
Results | Reference |
1 | J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6 |
Rsph14 radial spoke head homolog 14 (Chlamydomonas) (Synonyms: 4933431K05Rik, Rtdr1) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Rspo1 R-spondin 1 (Synonyms: R-spondin, Rspondin) | |
Results | Reference |
1 | J:307093 Amato CM, Yao HH, Developmental and sexual dimorphic atlas of the prenatal mouse external genitalia at the single-cell level. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2103856118 |
2 | J:239281 Caruso M, Ferranti F, Corano Scheri K, Dobrowolny G, Ciccarone F, Grammatico P, Catizone A, Ricci G, R-spondin 1/dickkopf-1/beta-catenin machinery is involved in testicular embryonic angiogenesis. PLoS One. 2015;10(4):e0124213 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:312814 Fernandez Vallone V, Leprovots M, Ribatallada-Soriano D, Gerbier R, Lefort A, Libert F, Vassart G, Garcia MI, LGR5 controls extracellular matrix production by stem cells in the developing intestine. EMBO Rep. 2020 Jul 3;21(7):e49224 |
1 | J:152858 Garcia-Ortiz JE, Pelosi E, Omari S, Nedorezov T, Piao Y, Karmazin J, Uda M, Cao A, Cole SW, Forabosco A, Schlessinger D, Ottolenghi C, Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Dev Biol. 2009;9:36 |
1 | J:246806 Li Y, Zhang L, Hu Y, Chen M, Han F, Qin Y, Chen M, Cui X, Duo S, Tang F, Gao F, beta-Catenin directs the transformation of testis Sertoli cells to ovarian granulosa-like cells by inducing Foxl2 expression. J Biol Chem. 2017 Oct 27;292(43):17577-17586 |
1 | J:321068 Maimets M, Pedersen MT, Guiu J, Dreier J, Thodberg M, Antoku Y, Schweiger PJ, Rib L, Bressan RB, Miao Y, Garcia KC, Sandelin A, Serup P, Jensen KB, Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling. Nat Commun. 2022 Feb 7;13(1):715 |
1 | J:328944 Olbertova K, Hrckulak D, Kriz V, Jesionek W, Kubovciak J, Esner M, Korinek V, Buchtova M, Role of LGR5-positive mesenchymal cells in craniofacial development. Front Cell Dev Biol. 2022;10:810527 |
Rspo2 R-spondin 2 (Synonyms: 2610028F08Rik, FLTL, ftls, Int7) | |
Results | Reference |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
1 | J:312814 Fernandez Vallone V, Leprovots M, Ribatallada-Soriano D, Gerbier R, Lefort A, Libert F, Vassart G, Garcia MI, LGR5 controls extracellular matrix production by stem cells in the developing intestine. EMBO Rep. 2020 Jul 3;21(7):e49224 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:328944 Olbertova K, Hrckulak D, Kriz V, Jesionek W, Kubovciak J, Esner M, Korinek V, Buchtova M, Role of LGR5-positive mesenchymal cells in craniofacial development. Front Cell Dev Biol. 2022;10:810527 |
1 | J:339937 Smith KS, Bihannic L, Gudenas BL, Haldipur P, Tao R, Gao Q, Li Y, Aldinger KA, Iskusnykh IY, Chizhikov VV, Scoggins M, Zhang S, Edwards A, Deng M, Glass IA, Overman LM, Millman J, Sjoboen AH, Hadley J, Golser J, Mankad K, Sheppard H, Onar-Thomas A, Gajjar A, Robinson GW, Hovestadt V, Orr BA, Patay Z, Millen KJ, Northcott PA, Unified rhombic lip origins of group 3 and group 4 medulloblastoma. Nature. 2022 Sep;609(7929):1012-1020 |
1* | J:146829 Yamada W, Nagao K, Horikoshi K, Fujikura A, Ikeda E, Inagaki Y, Kakitani M, Tomizuka K, Miyazaki H, Suda T, Takubo K, Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun. 2009 Apr 10;381(3):453-8 |
Rspo3 R-spondin 3 (Synonyms: 2810459H04Rik, Cristin1, Thsd2) | |
Results | Reference |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
1 | J:312814 Fernandez Vallone V, Leprovots M, Ribatallada-Soriano D, Gerbier R, Lefort A, Libert F, Vassart G, Garcia MI, LGR5 controls extracellular matrix production by stem cells in the developing intestine. EMBO Rep. 2020 Jul 3;21(7):e49224 |
1 | J:321068 Maimets M, Pedersen MT, Guiu J, Dreier J, Thodberg M, Antoku Y, Schweiger PJ, Rib L, Bressan RB, Miao Y, Garcia KC, Sandelin A, Serup P, Jensen KB, Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling. Nat Commun. 2022 Feb 7;13(1):715 |
1 | J:328944 Olbertova K, Hrckulak D, Kriz V, Jesionek W, Kubovciak J, Esner M, Korinek V, Buchtova M, Role of LGR5-positive mesenchymal cells in craniofacial development. Front Cell Dev Biol. 2022;10:810527 |
1 | J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005 |
Rspo4 R-spondin 4 (Synonyms: A930029K19Rik) | |
Results | Reference |
1 | J:312814 Fernandez Vallone V, Leprovots M, Ribatallada-Soriano D, Gerbier R, Lefort A, Libert F, Vassart G, Garcia MI, LGR5 controls extracellular matrix production by stem cells in the developing intestine. EMBO Rep. 2020 Jul 3;21(7):e49224 |
Rspry1 ring finger and SPRY domain containing 1 (Synonyms: 4930470D19Rik) | |
Results | Reference |
1* | J:230757 Faden M, AlZahrani F, Mendoza-Londono R, Dupuis L, Hartley T, Kannu P, Raiman JA, Howard A, Qin W, Tetreault M, Xi JQ, Al-Thamer I, Maas RL, Boycott K, Alkuraya FS, Identification of a Recognizable Progressive Skeletal Dysplasia Caused by RSPRY1 Mutations. Am J Hum Genet. 2015 Oct 1;97(4):608-15 |
Rtl1 retrotransposon Gaglike 1 (Synonyms: Mar, Mart1, Mor1) | |
Results | Reference |
2* | J:224145 Ito M, Sferruzzi-Perri AN, Edwards CA, Adalsteinsson BT, Allen SE, Loo TH, Kitazawa M, Kaneko-Ishino T, Ishino F, Stewart CL, Ferguson-Smith AC, A trans-homologue interaction between reciprocally imprinted miR-127 and Rtl1 regulates placenta development. Development. 2015 Jul 15;142(14):2425-30 |
2* | J:299191 Kitazawa M, Hayashi S, Imamura M, Takeda S, Oishi Y, Kaneko-Ishino T, Ishino F, Deficiency and overexpression of Rtl1 in the mouse cause distinct muscle abnormalities related to Temple and Kagami-Ogata syndromes. Development. 2020 Sep 2;147(21):dev185918 |
1 | J:309146 Kitazawa M, Sutani A, Kaneko-Ishino T, Ishino F, The role of eutherian-specific RTL1 in the nervous system and its implications for the Kagami-Ogata and Temple syndromes. Genes Cells. 2021 Mar;26(3):165-179 |
1* | J:166176 Zhou Y, Cheunsuchon P, Nakayama Y, Lawlor MW, Zhong Y, Rice KA, Zhang L, Zhang X, Gordon FE, Lidov HG, Bronson RT, Klibanski A, Activation of paternally expressed genes and perinatal death caused by deletion of the Gtl2 gene. Development. 2010 Aug;137(16):2643-52 |
Rtn1 reticulon 1 (Synonyms: 0710005K15Rik, 4930441F12Rik, MGC:40985, Nsp, Rtn1-a, Rtn1-b, Rtn1-c) | |
Results | Reference |
1* | J:313926 Cichon MA, Klas K, Buchberger M, Hammer M, Sere K, Zenke M, Tschachler E, Elbe-Burger A, Distinct Distribution of RTN1A in Immune Cells in Mouse Skin and Lymphoid Organs. Front Cell Dev Biol. 2020;8:608876 |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Rtn2 reticulon 2 (Z-band associated protein) (Synonyms: Nspl1) | |
Results | Reference |
1* | J:46660 Geisler JG, Stubbs LJ, Wasserman WW, Mucenski ML, Molecular cloning of a novel mouse gene with predominant muscle and neural expression. Mamm Genome. 1998 Apr;9(4):274-82 |
Rtn3 reticulon 3 | |
Results | Reference |
1* | J:76709 Hamada N, Iwahashi J, Suzuki K, Ogi H, Kashiwagi T, Hara K, Toyoda M, Yamada T, Toyoda T, Molecular cloning and characterization of the mouse reticulon 3 cDNA. Cell Mol Biol (Noisy-Le-Grand). 2002 Mar;48(2):163-72 |
Rtn4 reticulon 4 (Synonyms: 1110020G17Rik, C130026I10Rik, mKIAA0886, NgA, NOGO, Nogo-A, Nogo-B) | |
Results | Reference |
1 | J:118055 Mingorance-Le Meur A, Zheng B, Soriano E, del Rio JA, Involvement of the Myelin-associated inhibitor Nogo-A in early cortical development and neuronal maturation. Cereb Cortex. 2007 Oct;17(10):2375-86 |
2 | J:357471 Pagella P, Lai CF, Pirenne L, Cantu C, Schwab ME, Mitsiadis TA, An unexpected role of neurite outgrowth inhibitor A as regulator of tooth enamel formation. Int J Oral Sci. 2024;16(1):60 |
1 | J:136994 Wang J, Chan CK, Taylor JS, Chan SO, Localization of Nogo and its receptor in the optic pathway of mouse embryos. J Neurosci Res. 2008 Jun;86(8):1721-33 |
Rtn4rl2 reticulon 4 receptor-like 2 (Synonyms: Ngr2, Ngrh1, Ngrl3) | |
Results | Reference |
2 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Rufy3 RUN and FYVE domain containing 3 (Synonyms: 2810428M05Rik, 6330416M07Rik, D5Bwg0860e, mKIAA0871, Rpipx) | |
Results | Reference |
2* | J:253649 Honda A, Usui H, Sakimura K, Igarashi M, Rufy3 is an adapter protein for small GTPases that activates a Rac guanine nucleotide exchange factor to control neuronal polarity. J Biol Chem. 2017 Dec 22;292(51):20936-20946 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:214682 Wei Z, Sun M, Liu X, Zhang J, Jin Y, Rufy3, a protein specifically expressed in neurons, interacts with actin-bundling protein Fascin to control the growth of axons. J Neurochem. 2014 Sep;130(5):678-92 |
Runx1 runt related transcription factor 1 (Synonyms: AML1, Cbfa2, Pebp2a2, runt domain, alpha subunit 2) | |
Results | Reference |
1* | J:93240 Brenner O, Levanon D, Negreanu V, Golubkov O, Fainaru O, Woolf E, Groner Y, Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia. Proc Natl Acad Sci U S A. 2004 Dec 9;101(45):16016-21 |
1 | J:106971 Chen CL, Broom DC, Liu Y, de Nooij JC, Li Z, Cen C, Samad OA, Jessell TM, Woolf CJ, Ma Q, Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain. Neuron. 2006 Feb 2;49(3):365-77 |
1 | J:164668 Gascon E, Gaillard S, Malapert P, Liu Y, Rodat-Despoix L, Samokhvalov IM, Delmas P, Helmbacher F, Maina F, Moqrich A, Hepatocyte growth factor-Met signaling is required for Runx1 extinction and peptidergic differentiation in primary nociceptive neurons. J Neurosci. 2010 Sep 15;30(37):12414-23 |
1 | J:54133 Gjertson C, Sturm KS, Berger CN, Hematopoietic deficiencies and core binding factor expression in murine Ts16, an animal model for Down syndrome. Clin Immunol. 1999 Apr;91(1):50-60 |
1 | J:235517 Kam JW, Dumontier E, Baim C, Brignall AC, Mendes da Silva D, Cowan M, Kennedy TE, Cloutier JF, RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016 May 1;143(9):1534-46 |
2 | J:241125 Levanon D, Bernstein Y, Negreanu V, Bone KR, Pozner A, Eilam R, Lotem J, Brenner O, Groner Y, Absence of Runx3 expression in normal gastrointestinal epithelium calls into question its tumour suppressor function. EMBO Mol Med. 2011 Oct;3(10):593-604 |
2* | J:73303 Levanon D, Brenner O, Negreanu V, Bettoun D, Woolf E, Eilam R, Lotem J, Gat U, Otto F, Speck N, Groner Y, Spatial and temporal expression pattern of Runx3 (Aml2) and Runx1 (Aml1) indicates non-redundant functions during mouse embryogenesis. Mech Dev. 2001 Dec;109(2):413-7 |
1* | J:84279 Lian JB, Balint E, Javed A, Drissi H, Vitti R, Quinlan EJ, Zhang L, Van Wijnen AJ, Stein JL, Speck N, Stein GS, Runx1/AML1 hematopoietic transcription factor contributes to skeletal development in vivo. J Cell Physiol. 2003 Aug;196(2):301-11 |
1* | J:186470 Lopes C, Liu Z, Xu Y, Ma Q, Tlx3 and runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors. J Neurosci. 2012 Jul 11;32(28):9706-15 |
1 | J:330583 McKey J, Anbarci DN, Bunce C, Ontiveros AE, Behringer RR, Capel B, Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii. Elife. 2022 Sep 27;11:e81088 |
1 | J:211575 Murthy M, Bocking S, Verginelli F, Stifani S, Transcription factor Runx1 inhibits proliferation and promotes developmental maturation in a selected population of inner olfactory nerve layer olfactory ensheathing cells. Gene. 2014 May 1;540(2):191-200 |
1 | J:134495 Nakamura S, Senzaki K, Yoshikawa M, Nishimura M, Inoue K, Ito Y, Ozaki S, Shiga T, Dynamic regulation of the expression of neurotrophin receptors by Runx3. Development. 2008 May;135(9):1703-11 |
1 | J:281436 Nicol B, Grimm SA, Chalmel F, Lecluze E, Pannetier M, Pailhoux E, Dupin-De-Beyssat E, Guiguen Y, Capel B, Yao HH, RUNX1 maintains the identity of the fetal ovary through an interplay with FOXL2. Nat Commun. 2019 Nov 11;10(1):5116 |
2 | J:171374 Osorio KM, Lilja KC, Tumbar T, Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol. 2011 Apr 4;193(1):235-50 |
4 | J:125830 Pozner A, Lotem J, Xiao C, Goldenberg D, Brenner O, Negreanu V, Levanon D, Groner Y, Developmentally regulated promoter-switch transcriptionally controls Runx1 function during embryonic hematopoiesis. BMC Dev Biol. 2007;7:84 |
2 | J:142447 Sato S, Kimura A, Ozdemir J, Asou Y, Miyazaki M, Jinno T, Ae K, Liu X, Osaki M, Takeuchi Y, Fukumoto S, Kawaguchi H, Haro H, Shinomiya K, Karsenty G, Takeda S, The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration: Findings in murine models and in human disease. Arthritis Rheum. 2008 Sep;58(9):2764-75 |
1 | J:333986 Shrestha BR, Wu L, Goodrich LV, Runx1 controls auditory sensory neuron diversity in mice. Dev Cell. 2023 Feb 27;58(4):306-319.e5 |
2 | J:95959 Smith N, Dong Y, Lian JB, Pratap J, Kingsley PD, van Wijnen AJ, Stein JL, Schwarz EM, O'keefe RJ, Stein GS, Drissi MH, Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. J Cell Physiol. 2005 Apr;203(1):133-43 |
2 | J:101317 Stewart L, Potok MA, Camper SA, Stifani S, Runx1 expression defines a subpopulation of displaced amacrine cells in the developing mouse retina. J Neurochem. 2005 Sep;94(6):1739-45 |
1 | J:97371 Theriault FM, Nuthall HN, Dong Z, Lo R, Barnabe-Heider F, Miller FD, Stifani S, Role for Runx1 in the proliferation and neuronal differentiation of selected progenitor cells in the mammalian nervous system. J Neurosci. 2005 Feb 23;25(8):2050-61 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1 | J:187723 Zusso M, Methot L, Lo R, Greenhalgh AD, David S, Stifani S, Regulation of postnatal forebrain amoeboid microglial cell proliferation and development by the transcription factor runx1. J Neurosci. 2012 Aug 15;32(33):11285-98 |
Runx1t1 RUNX1 translocation partner 1 (Synonyms: Cbfa2t1h, ETO, MTG8) | |
Results | Reference |
2 | J:328140 Asgarian Z, Oliveira MG, Stryjewska A, Maragkos I, Rubin AN, Magno L, Pachnis V, Ghorbani M, Hiebert SW, Denaxa M, Kessaris N, MTG8 interacts with LHX6 to specify cortical interneuron subtype identity. Nat Commun. 2022 Sep 5;13(1):5217 |
Runx2 runt related transcription factor 2 (Synonyms: AML3, Cbfa1, Osf2, PEBP2aA, PEBP2 alpha A, Pebpa2a, polyomavirus enhancer binding factor 2 (PEBP2), SL3-3 enhancer factor 1) | |
Results | Reference |
1 | J:124269 Abzhanov A, Rodda SJ, McMahon AP, Tabin CJ, Regulation of skeletogenic differentiation in cranial dermal bone. Development. 2007 Sep;134(17):3133-44 |
1 | J:56557 Acampora D, Merlo GR, Paleari L, Zerega B, Postiglione MP, Mantero S, Bober E, Barbieri O, Simeone A, Levi G, Craniofacial, vestibular and bone defects in mice lacking the Distal-less-related gene Dlx5. Development. 1999 Sep;126(17):3795-809 |
1 | J:90567 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 2004 May 1;18(9):1072-87 |
2 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
1* | J:198100 Andreeva V, Cardarelli J, Yelick PC, Rb1 mRNA expression in developing mouse teeth. Gene Expr Patterns. 2012 Mar-Apr;12(3-4):130-5 |
1 | J:91667 Antonopoulou I, Mavrogiannis LA, Wilkie AO, Morriss-Kay GM, Alx4 and Msx2 play phenotypically similar and additive roles in skull vault differentiation. J Anat. 2004 Jun;204(6):487-99 |
1 | J:170583 Baek JA, Lan Y, Liu H, Maltby KM, Mishina Y, Jiang R, Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation. Dev Biol. 2011 Feb 15;350(2):520-31 |
1 | J:181527 Chaible LM, Sanches DS, Cogliati B, Mennecier G, Dagli ML, Delayed osteoblastic differentiation and bone development in Cx43 knockout mice. Toxicol Pathol. 2011 Dec;39(7):1046-55 |
1 | J:185530 Chan KM, Wong HL, Jin G, Liu B, Cao R, Cao Y, Lehti K, Tryggvason K, Zhou Z, MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis. Dev Cell. 2012 Jun 12;22(6):1176-90 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:283477 Chen D, Bashur LA, Liang B, Panattoni M, Tamai K, Pardi R, Zhou G, The transcriptional co-regulator Jab1 is crucial for chondrocyte differentiation in vivo. J Cell Sci. 2013 Jan 1;126(Pt 1):234-43 |
1* | J:311442 Chen W, Sheng P, Huang Z, Meng F, Kang Y, Huang G, Zhang Z, Liao W, Zhang Z, MicroRNA-381 Regulates Chondrocyte Hypertrophy by Inhibiting Histone Deacetylase 4 Expression. Int J Mol Sci. 2016 Aug 23;17(9):1377 |
1* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:327334 Choi KY, Lee SW, Park MH, Bae YC, Shin HI, Nam S, Kim YJ, Kim HJ, Ryoo HM, Spatio-temporal expression patterns of Runx2 isoforms in early skeletogenesis. Exp Mol Med. 2002 Dec 31;34(6):426-33 |
1* | J:66902 Colnot C, Sidhu SS, Balmain N, Poirier F, Uncoupling of chondrocyte death and vascular invasion in mouse galectin 3 null mutant bones. Dev Biol. 2001 Jan 1;229(1):203-14 |
1 | J:293199 Crespo-Enriquez I, Hodgson T, Zakaria S, Cadoni E, Shah M, Allen S, Al-Khishali A, Mao Y, Yiu A, Petzold J, Villagomez-Olea G, Pitsillides AA, Irvine KD, Francis-West P, Dchs1-Fat4 regulation of osteogenic differentiation in mouse. Development. 2019 Jul 29;146(14):dev176776 |
1 | J:54817 D'Souza RN, Aberg T, Gaikwad J, Cavender A, Owen M, Karsenty G, Thesleff I, Cbfa1 is required for epithelial-mesenchymal interactions regulating tooth development in mice. Development. 1999 JUL;126(13):2911-2920 |
1* | J:89221 Dacquin R, Mee PJ, Kawaguchi J, Olmsted-Davis EA, Gallagher JA, Nichols J, Lee K, Karsenty G, Smith A, Knock-in of nuclear localised beta-galactosidase reveals that the tyrosine phosphatase Ptprv is specifically expressed in cells of the bone collar. Dev Dyn. 2004 Apr;229(4):826-34 |
1 | J:146483 de Frutos CA, Dacquin R, Vega S, Jurdic P, Machuca-Gayet I, Nieto MA, Snail1 controls bone mass by regulating Runx2 and VDR expression during osteoblast differentiation. EMBO J. 2009 Mar 18;28(6):686-96 |
1* | J:317089 Du J, Wang Q, Yang P, Wang X, FHL2 mediates tooth development and human dental pulp cell differentiation into odontoblasts, partially by interacting with Runx2. J Mol Histol. 2016 Apr;47(2):195-202 |
1* | J:40781 Ducy P, Zhang R, Geoffroy V, Ridall AL, Karsenty G, Osf2/Cbfa1: a transcriptional activator of osteoblast differentiation. Cell. 1997 May 30;89(5):747-54 |
1 | J:127545 Engleka KA, Wu M, Zhang M, Antonucci NB, Epstein JA, Menin is required in cranial neural crest for palatogenesis and perinatal viability. Dev Biol. 2007 Nov 15;311(2):524-37 |
1* | J:61381 Enomoto H, Enomoto-Iwamoto M, Iwamoto M, Nomura S, Himeno M, Kitamura Y, Kishimoto T, Komori T, Cbfa1 is a positive regulatory factor in chondrocyte maturation. J Biol Chem. 2000 Mar 24;275(12):8695-702 |
1* | J:111429 Feng JQ, Zhang J, Dallas SL, Lu Y, Chen S, Tan X, Owen M, Harris SE, MacDougall M, Dentin matrix protein 1, a target molecule for Cbfa1 in bone, is a unique bone marker gene. J Bone Miner Res. 2002 Oct;17(10):1822-31 |
1 | J:217210 Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H, Loss of Tbx1 induces bone phenotypes similar to cleidocranial dysplasia. Hum Mol Genet. 2015 Jan 15;24(2):424-35 |
1* | J:203540 Gadi J, Jung SH, Lee MJ, Jami A, Ruthala K, Kim KM, Cho NH, Jung HS, Kim CH, Lim SK, The transcription factor protein Sox11 enhances early osteoblast differentiation by facilitating proliferation and the survival of mesenchymal and osteoblast progenitors. J Biol Chem. 2013 Aug 30;288(35):25400-13 |
1* | J:86790 Gitler AD, Lu MM, Jiang YQ, Epstein JA, Gruber PJ, Molecular markers of cardiac endocardial cushion development. Dev Dyn. 2003 Dec;228(4):643-50 |
1 | J:98430 Glass DA 2nd, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G, Canonical wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell. 2005 May;8(5):751-64 |
1* | J:236374 Goldie SJ, Arhatari BD, Anderson P, Auden A, Partridge DD, Jane SM, Dworkin S, Mice lacking the conserved transcription factor Grainyhead-like 3 (Grhl3) display increased apposition of the frontal and parietal bones during embryonic development. BMC Dev Biol. 2016 Oct 18;16(1):37 |
1* | J:70829 Gollner H, Dani C, Phillips B, Philipsen S, Suske G, Impaired ossification in mice lacking the transcription factor Sp3. Mech Dev. 2001 Aug;106(1-2):77-83 |
1 | J:74145 Gori F, Schipani E, Demay MB, Fibromodulin is expressed by both chondrocytes and osteoblasts during fetal bone development. J Cell Biochem. 2001 Apr 2-27;82(1):46-57 |
1 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
1 | J:150187 Guo X, Mak KK, Taketo MM, Yang Y, The Wnt/beta-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturation. PLoS One. 2009;4(6):e6067 |
1 | J:321579 Ha N, Sun J, Bian Q, Wu D, Wang X, Hdac4 Regulates the Proliferation of Neural Crest-Derived Osteoblasts During Murine Craniofacial Development. Front Physiol. 2022;13:819619 |
1 | J:146802 Harada M, Murakami H, Okawa A, Okimoto N, Hiraoka S, Nakahara T, Akasaka R, Shiraishi Y, Futatsugi N, Mizutani-Koseki Y, Kuroiwa A, Shirouzu M, Yokoyama S, Taiji M, Iseki S, Ornitz DM, Koseki H, FGF9 monomer-dimer equilibrium regulates extracellular matrix affinity and tissue diffusion. Nat Genet. 2009 Mar;41(3):289-98 |
1 | J:159025 Hattori T, Muller C, Gebhard S, Bauer E, Pausch F, Schlund B, Bosl MR, Hess A, Surmann-Schmitt C, von der Mark H, de Crombrugghe B, von der Mark K, SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification. Development. 2010 Mar;137(6):901-11 |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1 | J:98426 Hill TP, Spater D, Taketo MM, Birchmeier W, Hartmann C, Canonical Wnt/beta-Catenin Signaling Prevents Osteoblasts from Differentiating into Chondrocytes. Dev Cell. 2005 May;8(5):727-38 |
1 | J:114686 Hinoi E, Bialek P, Chen YT, Rached MT, Groner Y, Behringer RR, Ornitz DM, Karsenty G, Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes Dev. 2006 Nov 1;20(21):2937-42 |
1 | J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132 |
1 | J:286051 Holmes G, O'Rourke C, Motch Perrine SM, Lu N, van Bakel H, Richtsmeier JT, Jabs EW, Midface and upper airway dysgenesis in FGFR2-related craniosynostosis involves multiple tissue-specific and cell cycle effects. Development. 2018 Oct 5;145(19):dev166488 |
1* | J:220612 Holmes G, van Bakel H, Zhou X, Losic B, Jabs EW, BCL11B expression in intramembranous osteogenesis during murine craniofacial suture development. Gene Expr Patterns. 2015 Jan;17(1):16-25 |
1 | J:255577 Hsu WH, Chen CM, You LR, COUP-TFII is required for morphogenesis of the neural crest-derived tympanic ring. Sci Rep. 2017 Sep 28;7(1):12386 |
1* | J:292270 Ideno H, Nakashima K, Komatsu K, Araki R, Abe M, Arai Y, Kimura H, Shinkai Y, Tachibana M, Nifuji A, G9a is involved in the regulation of cranial bone formation through activation of Runx2 function during development. Bone. 2020 Aug;137:115332 |
1* | J:54095 Inada M, Yasui T, Nomura S, Miyake S, Deguchi K, Himeno M, Sato M, Yamagiwa H, Kimura T, Yasui N, Ochi T, Endo N, Kitamura Y, Kishimoto T, Komori T, Maturational disturbance of chondrocytes in Cbfa1-deficient mice. Dev Dyn. 1999 Apr;214(4):279-90 |
1 | J:155543 Inose H, Ochi H, Kimura A, Fujita K, Xu R, Sato S, Iwasaki M, Sunamura S, Takeuchi Y, Fukumoto S, Saito K, Nakamura T, Siomi H, Ito H, Arai Y, Shinomiya K, Takeda S, A microRNA regulatory mechanism of osteoblast differentiation. Proc Natl Acad Sci U S A. 2009 Dec 8;106(49):20794-9 |
1 | J:153633 Ito T, Yadav N, Lee J, Furumatsu T, Yamashita S, Yoshida K, Taniguchi N, Hashimoto M, Tsuchiya M, Ozaki T, Lotz M, Bedford MT, Asahara H, Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC Dev Biol. 2009;9:47 |
1* | J:191572 Iwasaki M, Piao J, Kimura A, Sato S, Inose H, Ochi H, Asou Y, Shinomiya K, Okawa A, Takeda S, Runx2 haploinsufficiency ameliorates the development of ossification of the posterior longitudinal ligament. PLoS One. 2012;7(8):e43372 |
1 | J:256071 Iyyanar PPR, Nazarali AJ, Hoxa2 Inhibits Bone Morphogenetic Protein Signaling during Osteogenic Differentiation of the Palatal Mesenchyme. Front Physiol. 2017;8:929 |
1 | J:119288 Jacob AL, Smith C, Partanen J, Ornitz DM, Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation. Dev Biol. 2006 Aug 15;296(2):315-28 |
1 | J:118173 Jarvinen E, Salazar-Ciudad I, Birchmeier W, Taketo MM, Jernvall J, Thesleff I, Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18627-32 |
1 | J:143588 Kamiya N, Ye L, Kobayashi T, Mochida Y, Yamauchi M, Kronenberg HM, Feng JQ, Mishina Y, BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development. 2008 Nov;135(22):3801-11 |
1 | J:143940 Kimura H, Kwan KM, Zhang Z, Deng JM, Darnay BG, Behringer RR, Nakamura T, de Crombrugghe B, Akiyama H, Cthrc1 is a positive regulator of osteoblastic bone formation. PLoS One. 2008;3(9):e3174 |
1 | J:263685 Kitami K, Kitami M, Kaku M, Wang B, Komatsu Y, BRCA1 and BRCA2 tumor suppressors in neural crest cells are essential for craniofacial bone development. PLoS Genet. 2018 May;14(5):e1007340 |
1 | J:92212 Koziel L, Kunath M, Kelly OG, Vortkamp A, Ext1-dependent heparan sulfate regulates the range of Ihh signaling during endochondral ossification. Dev Cell. 2004 Jun;6(6):801-13 |
1 | J:233640 Kyrylkova K, Iwaniec UT, Philbrick KA, Leid M, BCL11B regulates sutural patency in the mouse craniofacial skeleton. Dev Biol. 2016 Jul 15;415(2):251-60 |
2 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
1 | J:182649 Levi B, James AW, Nelson ER, Brugmann SA, Sorkin M, Manu A, Longaker MT, Role of Indian hedgehog signaling in palatal osteogenesis. Plast Reconstr Surg. 2011 Mar;127(3):1182-90 |
1 | J:317557 Li X, Liu H, Gu S, Liu C, Sun C, Zheng Y, Chen Y, Replacing Shox2 with human SHOX leads to congenital disc degeneration of the temporomandibular joint in mice. Cell Tissue Res. 2014 Feb;355(2):345-54 |
1 | J:319475 Liao C, Lu M, Hong Y, Mao C, Chen J, Ren C, Lin M, Chen W, Osteogenic and angiogenic profiles of the palatal process of the maxilla and the palatal process of the palatine bone. J Anat. 2022 Feb;240(2):385-397 |
1 | J:88635 Long F, Chung UI, Ohba S, McMahon J, Kronenberg HM, McMahon AP, Ihh signaling is directly required for the osteoblast lineage in the endochondral skeleton. Development. 2004 Mar;131(6):1309-18 |
1 | J:152843 Luo J, Zhou W, Zhou X, Li D, Weng J, Yi Z, Cho SG, Li C, Yi T, Wu X, Li XY, de Crombrugghe B, Hook M, Liu M, Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development. 2009 Aug;136(16):2747-56 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1* | J:74493 Maes C, Carmeliet P, Moermans K, Stockmans I, Smets N, Collen D, Bouillon R, Carmeliet G, Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF(164) and VEGF(188). Mech Dev. 2002 Feb;111(1-2):61-73 |
1* | J:160674 Mai S, Wei K, Flenniken A, Adamson SL, Rossant J, Aubin JE, Gong SG, The missense mutation W290R in Fgfr2 causes developmental defects from aberrant IIIb and IIIc signaling. Dev Dyn. 2010 Jun;239(6):1888-900 |
1 | J:193853 Makino Y, Takahashi Y, Tanabe R, Tamamura Y, Watanabe T, Haraikawa M, Hamagaki M, Hata K, Kanno J, Yoneda T, Saga Y, Goseki-Sone M, Kaneko K, Yamaguchi A, Iimura T, Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone. 2013 Mar;53(1):248-58 |
1 | J:149225 Miclea RL, Karperien M, Bosch CA, van der Horst G, van der Valk MA, Kobayashi T, Kronenberg HM, Rawadi G, Akcakaya P, Lowik CW, Fodde R, Wit JM, Robanus-Maandag EC, Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors. BMC Dev Biol. 2009;9:26 |
1* | J:153103 Mikura A, Okuhara S, Saito M, Ota M, Ueda K, Iseki S, Association of tenascin-W expression with mineralization in mouse calvarial development. Congenit Anom (Kyoto). 2009 Jun;49(2):77-84 |
1 | J:276880 Motch Perrine SM, Wu M, Stephens NB, Kriti D, van Bakel H, Jabs EW, Richtsmeier JT, Mandibular dysmorphology due to abnormal embryonic osteogenesis in FGFR2-related craniosynostosis mice. Dis Model Mech. 2019 May 30;12(5):dmm038513 |
1* | J:74344 Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B, The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 2002 Jan 11;108(1):17-29 |
1* | J:297164 Nie X, Zheng J, Cruciger M, Yang P, Mao JJ, mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev Biol. 2020 Nov 1;467(1-2):77-87 |
1 | J:165333 Nishikawa K, Nakashima T, Takeda S, Isogai M, Hamada M, Kimura A, Kodama T, Yamaguchi A, Owen MJ, Takahashi S, Takayanagi H, Maf promotes osteoblast differentiation in mice by mediating the age-related switch in mesenchymal cell differentiation. J Clin Invest. 2010 Oct 1;120(10):3455-65 |
1* | J:319569 Ohira T, Spear D, Azimi N, Andreeva V, Yelick PC, Chemerin-ChemR23 signaling in tooth development. J Dent Res. 2012 Dec;91(12):1147-53 |
1* | J:40784 Otto F, Thornell AP, Crompton T, Denzel A, Gilmour KC, Rosewell IR , Stamp GW , Beddington RS , Mundlos S , Olsen BR , Selby PB , Owen MJ, Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development. Cell. 1997 May 30;89(5):765-71 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1* | J:265842 Palagano E, Zuccarini G, Prontera P, Borgatti R, Stangoni G, Elisei S, Mantero S, Menale C, Forlino A, Uva P, Oppo M, Vezzoni P, Villa A, Merlo GR, Sobacchi C, Mutations in the Neuroblastoma Amplified Sequence gene in a family affected by Acrofrontofacionasal Dysostosis type 1. Bone. 2018 Sep;114:125-136 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
1 | J:299239 Qin X, Jiang Q, Nagano K, Moriishi T, Miyazaki T, Komori H, Ito K, Mark KV, Sakane C, Kaneko H, Komori T, Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts. PLoS Genet. 2020 Nov;16(11):e1009169 |
1 | J:163175 Rice DP, Connor EC, Veltmaat JM, Lana-Elola E, Veistinen L, Tanimoto Y, Bellusci S, Rice R, Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation. Hum Mol Genet. 2010 Sep 1;19(17):3457-67 |
1 | J:76480 Robledo RF, Rajan L, Li X, Lufkin T, The Dlx5 and Dlx6 homeobox genes are essential for craniofacial, axial, and appendicular skeletal development. Genes Dev. 2002 May 1;16(9):1089-101 |
1 | J:340421 Ruscitto A, Chen P, Tosa I, Wang Z, Zhou G, Safina I, Wei R, Morel MM, Koch A, Forman M, Reeve G, Lecholop MK, Wilson M, Bonthius D, Chen M, Ono M, Wang TC, Yao H, Embree MC, Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity. Cell Stem Cell. 2023 Sep 7;30(9):1179-1198.e7 |
2 | J:142447 Sato S, Kimura A, Ozdemir J, Asou Y, Miyazaki M, Jinno T, Ae K, Liu X, Osaki M, Takeuchi Y, Fukumoto S, Kawaguchi H, Haro H, Shinomiya K, Karsenty G, Takeda S, The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration: Findings in murine models and in human disease. Arthritis Rheum. 2008 Sep;58(9):2764-75 |
2 | J:95959 Smith N, Dong Y, Lian JB, Pratap J, Kingsley PD, van Wijnen AJ, Stein JL, Schwarz EM, O'keefe RJ, Stein GS, Drissi MH, Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. J Cell Physiol. 2005 Apr;203(1):133-43 |
1* | J:80666 Smits P, Li P, Mandel J, Zhang Z, Deng JM, Behringer RR, de Croumbrugghe B, Lefebvre V, The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001 Aug;1(2):277-90 |
1 | J:171003 Sugito H, Shibukawa Y, Kinumatsu T, Yasuda T, Nagayama M, Yamada S, Minugh-Purvis N, Pacifici M, Koyama E, Ihh signaling regulates mandibular symphysis development and growth. J Dent Res. 2011 May;90(5):625-31 |
1 | J:333326 Suh J, Kim NK, Shim W, Lee SH, Kim HJ, Moon E, Sesaki H, Jang JH, Kim JE, Lee YS, Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab. 2023 Feb 7;35(2):345-360.e7 |
1* | J:67784 Takeda S, Bonnamy JP, Owen MJ, Ducy P, Karsenty G, Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. Genes Dev. 2001 Feb 15;15(4):467-81 |
1 | J:125052 Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H, Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification. Mol Cell Biol. 2007 Aug;27(16):5650-63 |
1* | J:87170 Thomas G, Moffatt P, Salois P, Gaumond MH, Gingras R, Godin E, Miao D, Goltzman D, Lanctot C, Osteocrin, a novel bone-specific secreted protein that modulates the osteoblast phenotype. J Biol Chem. 2003 Dec 12;278(50):50563-71 |
1 | J:345132 Umar M, Dong C, He F, Characterizing expression pattern of Six2Cre during mouse craniofacial development. Genesis. 2023 Sep;61(5):e23516 |
1 | J:94631 Vega RB, Matsuda K, Oh J, Barbosa AC, Yang X, Meadows E, McAnally J, Pomajzl C, Shelton JM, Richardson JA, Karsenty G, Olson EN, Histone deacetylase 4 controls chondrocyte hypertrophy during skeletogenesis. Cell. 2004 Nov 12;119(4):555-66 |
1* | J:289500 Veistinen L, Takatalo M, Tanimoto Y, Kesper DA, Vortkamp A, Rice DP, Loss-of-Function of Gli3 in Mice Causes Abnormal Frontal Bone Morphology and Premature Synostosis of the Interfrontal Suture. Front Physiol. 2012;3:121 |
1 | J:161451 Villavicencio-Lorini P, Kuss P, Friedrich J, Haupt J, Farooq M, Turkmen S, Duboule D, Hecht J, Mundlos S, Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. J Clin Invest. 2010 Jun 1;120(6):1994-2004 |
1 | J:132462 Wang K, Yamamoto H, Chin JR, Werb Z, Vu TH, Epidermal growth factor receptor-deficient mice have delayed primary endochondral ossification because of defective osteoclast recruitment. J Biol Chem. 2004 Dec 17;279(51):53848-56 |
1 | J:286823 Wang L, Tang Q, Xu J, Li H, Yang T, Li L, Machon O, Hu T, Chen Y, The transcriptional regulator MEIS2 sets up the ground state for palatal osteogenesis in mice. J Biol Chem. 2020 Apr 17;295(16):5449-5460 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1* | J:306094 Xiao Y, Lin YX, Cui Y, Zhang Q, Pei F, Zuo HY, Liu H, Chen Z, Zeb1 Promotes Odontoblast Differentiation in a Stage-Dependent Manner. J Dent Res. 2021 Jun;100(6):648-657 |
1 | J:281388 Xu J, Huang Z, Wang W, Tan X, Li H, Zhang Y, Tian W, Hu T, Chen YP, FGF8 Signaling Alters the Osteogenic Cell Fate in the Hard Palate. J Dent Res. 2018 May;97(5):589-596 |
1 | J:283053 Xu J, Wang L, Li H, Yang T, Zhang Y, Hu T, Huang Z, Chen Y, Shox2 regulates osteogenic differentiation and pattern formation during hard palate development in mice. J Biol Chem. 2019 Nov 29;294(48):18294-18305 |
1 | J:102996 Yamaai T, Nakanishi T, Asano M, Nawachi K, Yoshimichi G, Ohyama K, Komori T, Sugimoto T, Takigawa M, Gene expression of connective tissue growth factor (CTGF/CCN2) in calcifying tissues of normal and cbfa1-null mutant mice in late stage of embryonic development. J Bone Miner Metab. 2005;23(4):280-8 |
1 | J:320311 Yang L, Gu S, Ye W, Song Y, Chen Y, Augmented Indian hedgehog signaling in cranial neural crest cells leads to craniofacial abnormalities and dysplastic temporomandibular joint in mice. Cell Tissue Res. 2016 Apr;364(1):105-15 |
1 | J:360708 Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K, Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase. Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2320070121 |
1* | J:334015 Yoshioka H, Komura S, Kuramitsu N, Goto A, Hasegawa T, Amizuka N, Ishimoto T, Ozasa R, Nakano T, Imai Y, Akiyama H, Deletion of Tfam in Prx1-Cre expressing limb mesenchyme results in spontaneous bone fractures. J Bone Miner Metab. 2022 Sep;40(5):839-852 |
1* | J:90391 Yu K, Xu J, Liu Z, Sosic D, Shao J, Olson EN, Towler DA, Ornitz DM, Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development. 2003 Jul;130(13):3063-74 |
1 | J:329949 Yuan H, Xie B, Yu X, Lin C, Li M, Zhang Y, Zou X, Lu M, Zhao M, Wen X, A potential role of p75NTR in the regulation of circadian rhythm and incremental growth lines during tooth development. Front Physiol. 2022;13:981311 |
1 | J:195329 Zee T, Boller S, Gyory I, Makinistoglu MP, Tuckermann JP, Grosschedl R, Karsenty G, The transcription factor early B-cell factor 1 regulates bone formation in an osteoblast-nonautonomous manner. FEBS Lett. 2013 Mar 18;587(6):711-6 |
1 | J:168525 Zhang S, Xiao Z, Luo J, He N, Mahlios J, Quarles LD, Dose-dependent effects of Runx2 on bone development. J Bone Miner Res. 2009 Nov;24(11):1889-904 |
2 | J:202215 Zhang X, Ting K, Bessette CM, Culiat CT, Sung SJ, Lee H, Chen F, Shen J, Wang JJ, Kuroda S, Soo C, Nell-1, a key functional mediator of Runx2, partially rescues calvarial defects in Runx2(+/-) mice. J Bone Miner Res. 2011 Apr;26(4):777-91 |
1 | J:202210 Zhang X, Ting K, Pathmanathan D, Ko T, Chen W, Chen F, Lee H, James AW, Siu RK, Shen J, Culiat CT, Soo C, Calvarial cleidocraniodysplasia-like defects with ENU-induced Nell-1 deficiency. J Craniofac Surg. 2012 Jan;23(1):61-6 |
1* | J:87163 Zhang Z, Song Y, Zhang X, Tang J, Chen J, Chen Y, Msx1/Bmp4 genetic pathway regulates mammalian alveolar bone formation via induction of Dlx5 and Cbfa1. Mech Dev. 2003 Dec;120(12):1469-79 |
1 | J:218833 Zhao H, Zhou W, Yao Z, Wan Y, Cao J, Zhang L, Zhao J, Li H, Zhou R, Li B, Wei G, Zhang Z, French CA, Dekker JD, Yang Y, Fisher SE, Tucker HO, Guo X, Foxp1/2/4 regulate endochondral ossification as a suppresser complex. Dev Biol. 2015 Feb 15;398(2):242-54 |
1 | J:228857 Zhu X, Wang F, Zhao Y, Yang P, Chen J, Sun H, Liu L, Li W, Pan L, Guo Y, Kou Z, Zhang Y, Zhou C, He J, Zhang X, Li J, Han W, Li J, Liu G, Gao S, Yang Z, A gain-of-function mutation in Tnni2 impeded bone development through increasing Hif3a expression in DA2B mice. PLoS Genet. 2014 Oct;10(10):e1004589 |
Runx3 runt related transcription factor 3 (Synonyms: AML2, Cbfa3, Rx3) | |
Results | Reference |
1 | J:224290 Bauer O, Sharir A, Kimura A, Hantisteanu S, Takeda S, Groner Y, Loss of osteoblast Runx3 produces severe congenital osteopenia. Mol Cell Biol. 2015 Apr;35(7):1097-109 |
1* | J:93240 Brenner O, Levanon D, Negreanu V, Golubkov O, Fainaru O, Woolf E, Groner Y, Loss of Runx3 function in leukocytes is associated with spontaneously developed colitis and gastric mucosal hyperplasia. Proc Natl Acad Sci U S A. 2004 Dec 9;101(45):16016-21 |
1 | J:345844 Guo Y, Xiang P, Sun X, Liu W, Zhou J, Yin B, Hou L, Qiang B, Li H, Shu P, Peng X, Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy. Signal Transduct Target Ther. 2024 Feb 14;9(1):32 |
1 | J:114686 Hinoi E, Bialek P, Chen YT, Rached MT, Groner Y, Behringer RR, Ornitz DM, Karsenty G, Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes Dev. 2006 Nov 1;20(21):2937-42 |
1 | J:100886 Hippenmeyer S, Vrieseling E, Sigrist M, Portmann T, Laengle C, Ladle DR, Arber S, A developmental switch in the response of DRG neurons to ETS transcription factor signaling. PLoS Biol. 2005 May;3(5):e159 |
1* | J:199186 Juuri E, Saito K, Lefebvre S, Michon F, Establishment of crown-root domain borders in mouse incisor. Gene Expr Patterns. 2013 Oct;13(7):255-64 |
1 | J:241125 Levanon D, Bernstein Y, Negreanu V, Bone KR, Pozner A, Eilam R, Lotem J, Brenner O, Groner Y, Absence of Runx3 expression in normal gastrointestinal epithelium calls into question its tumour suppressor function. EMBO Mol Med. 2011 Oct;3(10):593-604 |
1 | J:77764 Levanon D, Bettoun D, Harris-Cerruti C, Woolf E, Negreanu V, Eilam R, Bernstein Y, Goldenberg D, Xiao C, Fliegauf M, Kremer E, Otto F, Brenner O, Lev-Tov A, Groner Y, The Runx3 transcription factor regulates development and survival of TrkC dorsal root ganglia neurons. EMBO J. 2002 Jul 1;21(13):3454-63 |
1* | J:73303 Levanon D, Brenner O, Negreanu V, Bettoun D, Woolf E, Eilam R, Lotem J, Gat U, Otto F, Speck N, Groner Y, Spatial and temporal expression pattern of Runx3 (Aml2) and Runx1 (Aml1) indicates non-redundant functions during mouse embryogenesis. Mech Dev. 2001 Dec;109(2):413-7 |
1 | J:134495 Nakamura S, Senzaki K, Yoshikawa M, Nishimura M, Inoue K, Ito Y, Ozaki S, Shiga T, Dynamic regulation of the expression of neurotrophin receptors by Runx3. Development. 2008 May;135(9):1703-11 |
1 | J:99572 Raveh E, Cohen S, Levanon D, Groner Y, Gat U, Runx3 is involved in hair shape determination. Dev Dyn. 2005 Aug;233(4):1478-87 |
2 | J:142447 Sato S, Kimura A, Ozdemir J, Asou Y, Miyazaki M, Jinno T, Ae K, Liu X, Osaki M, Takeuchi Y, Fukumoto S, Kawaguchi H, Haro H, Shinomiya K, Karsenty G, Takeda S, The distinct role of the Runx proteins in chondrocyte differentiation and intervertebral disc degeneration: Findings in murine models and in human disease. Arthritis Rheum. 2008 Sep;58(9):2764-75 |
2 | J:124088 Soung do Y, Dong Y, Wang Y, Zuscik MJ, Schwarz EM, O'Keefe RJ, Drissi H, Runx3/AML2/Cbfa3 regulates early and late chondrocyte differentiation. J Bone Miner Res. 2007 Aug;22(8):1260-70 |
2* | J:174179 Yamamoto H, Ito K, Kawai M, Murakami Y, Bessho K, Ito Y, Runx3 expression during mouse tongue and palate development. Anat Rec A Discov Mol Cell Evol Biol. 2006 Jul;288(7):695-9 |
1 | J:89327 Yoshida CA, Yamamoto H, Fujita T, Furuichi T, Ito K, Inoue K, Yamana K, Zanma A, Takada K, Ito Y, Komori T, Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog. Genes Dev. 2004 Apr 15;18(8):952-63 |
1 | J:358835 Zhang J, Gao J, Zeng X, Wang Z, Chen C, Rong C, Li S, Cai L, Wang L, Zhang L, Tian Z, A novel Cdc42-YAP-fibronectin signaling axis regulates ameloblast differentiation during early enamel formation. Biochim Biophys Acta Mol Basis Dis. 2024 Nov 14;1871(2):167570 |
Rxfp1 relaxin/insulin-like family peptide receptor 1 (Synonyms: Lgr7, LOC381489) | |
Results | Reference |
1 | J:219254 Duarte C, Kobayashi Y, Kawamoto T, Moriyama K, RELAXIN enhances differentiation and matrix mineralization through Relaxin/insulin-like family peptide receptor 2 (Rxfp2) in MC3T3-E1 cells in vitro. Bone. 2014 Aug;65:92-101 |
Rxfp2 relaxin/insulin-like family peptide receptor 2 (Synonyms: Gpr106, Great, LGR8) | |
Results | Reference |
1 | J:219254 Duarte C, Kobayashi Y, Kawamoto T, Moriyama K, RELAXIN enhances differentiation and matrix mineralization through Relaxin/insulin-like family peptide receptor 2 (Rxfp2) in MC3T3-E1 cells in vitro. Bone. 2014 Aug;65:92-101 |
1 | J:122478 Feng S, Bogatcheva NV, Truong A, Korchin B, Bishop CE, Klonisch T, Agoulnik IU, Agoulnik AI, Devlopmental Expression and gene regulations of insulin-like 3 receptor RXFP2 in mouse male reproductive organs. Biol Reprod. 2007 Oct;77(4):671-80 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
Rxfp3 relaxin family peptide receptor 3 (Synonyms: Rln3r1, Salpr) | |
Results | Reference |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
Rxra retinoid X receptor alpha (Synonyms: 9530071D11Rik, RXR alpha 1, RXRalpha1) | |
Results | Reference |
1 | J:20940 Bloch-Zupan A, Decimo D, Loriot M, Mark MP, Ruch JV, Expression of nuclear retinoic acid receptors during mouse odontogenesis. Differentiation. 1994 Sep;57(3):195-203 |
1* | J:256937 Bohnenpoll T, Weiss AC, Labuhn M, Ludtke TH, Trowe MO, Kispert A, Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter. Sci Rep. 2017 Nov 1;7(1):14803 |
2* | J:17147 Dolle P, Fraulob V, Kastner P, Chambon P, Developmental expression of murine retinoid X receptor (RXR) genes. Mech Dev. 1994 Feb;45(2):91-104 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1* | J:189008 Jia Y, Viswakarma N, Crawford SE, Sarkar J, Sambasiva Rao M, Karpus WJ, Kanwar YS, Zhu YJ, Reddy JK, Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. Mech Dev. 2012 Sep;129(9-12):193-207 |
1* | J:88404 Nishizawa H, Manabe N, Morita M, Sugimoto M, Imanishi S, Miyamoto H, Effects of in utero exposure to bisphenol A on expression of RARalpha and RXRalpha mRNAs in murine embryos. J Reprod Dev. 2003 Dec;49(6):539-45 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
2* | J:134349 Vezina CM, Allgeier SH, Fritz WA, Moore RW, Strerath M, Bushman W, Peterson RE, Retinoic acid induces prostatic bud formation. Dev Dyn. 2008 May;237(5):1321-33 |
Rxrb retinoid X receptor beta (Synonyms: H-2RIIBP, Nr2b2, RCoR-1, Rub) | |
Results | Reference |
1 | J:20940 Bloch-Zupan A, Decimo D, Loriot M, Mark MP, Ruch JV, Expression of nuclear retinoic acid receptors during mouse odontogenesis. Differentiation. 1994 Sep;57(3):195-203 |
1* | J:256937 Bohnenpoll T, Weiss AC, Labuhn M, Ludtke TH, Trowe MO, Kispert A, Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter. Sci Rep. 2017 Nov 1;7(1):14803 |
2* | J:17147 Dolle P, Fraulob V, Kastner P, Chambon P, Developmental expression of murine retinoid X receptor (RXR) genes. Mech Dev. 1994 Feb;45(2):91-104 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
2 | J:142312 Murai J, Ikegami D, Okamoto M, Yoshikawa H, Tsumaki N, Insulation of the ubiquitous Rxrb promoter from the cartilage-specific adjacent gene, Col11a2. J Biol Chem. 2008 Oct 10;283(41):27677-87 |
2* | J:134349 Vezina CM, Allgeier SH, Fritz WA, Moore RW, Strerath M, Bushman W, Peterson RE, Retinoic acid induces prostatic bud formation. Dev Dyn. 2008 May;237(5):1321-33 |
Rxrg retinoid X receptor gamma (Synonyms: Nr2b3) | |
Results | Reference |
1 | J:273194 Anderson SR, Zhang J, Steele MR, Romero CO, Kautzman AG, Schafer DP, Vetter ML, Complement Targets Newborn Retinal Ganglion Cells for Phagocytic Elimination by Microglia. J Neurosci. 2019 Mar 13;39(11):2025-2040 |
1 | J:20940 Bloch-Zupan A, Decimo D, Loriot M, Mark MP, Ruch JV, Expression of nuclear retinoic acid receptors during mouse odontogenesis. Differentiation. 1994 Sep;57(3):195-203 |
1* | J:256937 Bohnenpoll T, Weiss AC, Labuhn M, Ludtke TH, Trowe MO, Kispert A, Retinoic acid signaling maintains epithelial and mesenchymal progenitors in the developing mouse ureter. Sci Rep. 2017 Nov 1;7(1):14803 |
2* | J:17147 Dolle P, Fraulob V, Kastner P, Chambon P, Developmental expression of murine retinoid X receptor (RXR) genes. Mech Dev. 1994 Feb;45(2):91-104 |
1 | J:304642 Dupacova N, Antosova B, Paces J, Kozmik Z, Meis homeobox genes control progenitor competence in the retina. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2013136118 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:44591 Garel S, Marin F, Grosschedl R, Charnay P, Ebf1 controls early cell differentiation in the embryonic striatum. Development. 1999 Dec;126(23):5285-94 |
1* | J:159513 Huang J, Bi Y, Zhu GH, He Y, Su Y, He BC, Wang Y, Kang Q, Chen L, Zuo GW, Luo Q, Shi Q, Zhang BQ, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Retinoic acid signalling induces the differentiation of mouse fetal liver-derived hepatic progenitor cells. Liver Int. 2009 Nov;29(10):1569-81 |
1 | J:214082 Maurer KA, Riesenberg AN, Brown NL, Notch signaling differentially regulates Atoh7 and Neurog2 in the distal mouse retina. Development. 2014 Aug;141(16):3243-54 |
1 | J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
2* | J:134349 Vezina CM, Allgeier SH, Fritz WA, Moore RW, Strerath M, Bushman W, Peterson RE, Retinoic acid induces prostatic bud formation. Dev Dyn. 2008 May;237(5):1321-33 |
Rybp RING1 and YY1 binding protein (Synonyms: 2410018J24Rik, DEDAF, MGC:62213) | |
Results | Reference |
1* | J:134591 Pirity MK, Locker J, Schreiber-Agus N, Rybp/DEDAF is required for early postimplantation and for central nervous system development. Mol Cell Biol. 2005 Aug;25(16):7193-202 |
1 | J:134428 Pirity MK, Wang WL, Wolf LV, Tamm ER, Schreiber-Agus N, Cvekl A, Rybp, a polycomb complex-associated protein, is required for mouse eye development. BMC Dev Biol. 2007;7:39 |
Ryk receptor-like tyrosine kinase (Synonyms: ERK-3, Vik) | |
Results | Reference |
1 | J:283040 McKenzie MG, Cobbs LV, Dummer PD, Petros TJ, Halford MM, Stacker SA, Zou Y, Fishell GJ, Au E, Non-canonical Wnt Signaling through Ryk Regulates the Generation of Somatostatin- and Parvalbumin-Expressing Cortical Interneurons. Neuron. 2019 Sep 4;103(5):853-864.e4 |
3 | J:52203 Serfas MS, Tyner AL, Ryk is expressed in a differentiation-specific manner in epithelial tissues and is strongly induced in decidualizing uterine stroma. Oncogene. 1998 Dec 31;17(26):3435-44 |
1* | J:297051 Wang S, Roy JP, Tomlinson AJ, Wang EB, Tsai YH, Cameron L, Underwood J, Spence JR, Walton KD, Stacker SA, Gumucio DL, Lechler T, RYK-mediated filopodial pathfinding facilitates midgut elongation. Development. 2020 Oct 27;147(20):dev195388 |
1 | J:170544 Zhong J, Kim HT, Lyu J, Yoshikawa K, Nakafuku M, Lu W, The Wnt receptor Ryk controls specification of GABAergic neurons versus oligodendrocytes during telencephalon development. Development. 2011 Feb;138(3):409-19 |
Ryr1 ryanodine receptor 1, skeletal muscle (Synonyms: calcium release channel isoform 1, Ryr, skrr) | |
Results | Reference |
2* | J:79406 Faure AV, Grunwald D, Moutin MJ, Hilly M, Mauger JP, Marty I, De Waard M, Villaz M, Albrieux M, Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex. Eur J Neurosci. 2001 Nov;14(10):1613-22 |
2 | J:194896 Pistocchi A, Gaudenzi G, Foglia E, Monteverde S, Moreno-Fortuny A, Pianca A, Cossu G, Cotelli F, Messina G, Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution. Development. 2013 Apr;140(7):1528-36 |
1* | J:53109 Rosemblit N, Moschella MC, Ondriasa E, Gutstein DE, Ondrias K, Marks AR, Intracellular calcium release channel expression during embryogenesis. Dev Biol. 1999 Feb 15;206(2):163-77 |
1 | J:72636 Takekura H, Flucher BE, Franzini-Armstrong C, Sequential Docking, Molecular Differentiation, and Positioning of T-Tubule/SR Junctions in Developing Mouse Skeletal Muscle. Dev Biol. 2001 Nov 15;239(2):204-14 |
1 | J:200792 Wang P, Tang M, Gao L, Luo H, Wang G, Ma X, Duan Y, Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development. J Cell Biochem. 2013 Aug;114(8):1852-62 |
Ryr2 ryanodine receptor 2, cardiac (Synonyms: 9330127I20Rik) | |
Results | Reference |
2* | J:79406 Faure AV, Grunwald D, Moutin MJ, Hilly M, Mauger JP, Marty I, De Waard M, Villaz M, Albrieux M, Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex. Eur J Neurosci. 2001 Nov;14(10):1613-22 |
1* | J:97586 Hong S, Kim TW, Choi I, Woo JM, Oh J, Park WJ, Kim do H, Cho C, Complementary DNA cloning, genomic characterization and expression analysis of a mammalian gene encoding histidine-rich calcium binding protein. Biochim Biophys Acta. 2005 Mar 10;1727(3):188-96 |
2 | J:194896 Pistocchi A, Gaudenzi G, Foglia E, Monteverde S, Moreno-Fortuny A, Pianca A, Cossu G, Cotelli F, Messina G, Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution. Development. 2013 Apr;140(7):1528-36 |
1* | J:53109 Rosemblit N, Moschella MC, Ondriasa E, Gutstein DE, Ondrias K, Marks AR, Intracellular calcium release channel expression during embryogenesis. Dev Biol. 1999 Feb 15;206(2):163-77 |
1 | J:72636 Takekura H, Flucher BE, Franzini-Armstrong C, Sequential Docking, Molecular Differentiation, and Positioning of T-Tubule/SR Junctions in Developing Mouse Skeletal Muscle. Dev Biol. 2001 Nov 15;239(2):204-14 |
1 | J:200792 Wang P, Tang M, Gao L, Luo H, Wang G, Ma X, Duan Y, Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development. J Cell Biochem. 2013 Aug;114(8):1852-62 |
Ryr3 ryanodine receptor 3 (Synonyms: calcium release channel isoform 3) | |
Results | Reference |
2* | J:79406 Faure AV, Grunwald D, Moutin MJ, Hilly M, Mauger JP, Marty I, De Waard M, Villaz M, Albrieux M, Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex. Eur J Neurosci. 2001 Nov;14(10):1613-22 |
2 | J:194896 Pistocchi A, Gaudenzi G, Foglia E, Monteverde S, Moreno-Fortuny A, Pianca A, Cossu G, Cotelli F, Messina G, Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution. Development. 2013 Apr;140(7):1528-36 |
1 | J:72636 Takekura H, Flucher BE, Franzini-Armstrong C, Sequential Docking, Molecular Differentiation, and Positioning of T-Tubule/SR Junctions in Developing Mouse Skeletal Muscle. Dev Biol. 2001 Nov 15;239(2):204-14 |
1 | J:200792 Wang P, Tang M, Gao L, Luo H, Wang G, Ma X, Duan Y, Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development. J Cell Biochem. 2013 Aug;114(8):1852-62 |
S1pr1 sphingosine-1-phosphate receptor 1 (Synonyms: Edg1, S1P, S1P1) | |
Results | Reference |
1 | J:41657 Liu CH, Hla T, The mouse gene for the inducible G-protein-coupled receptor edg-1. Genomics. 1997 Jul 1;43(1):15-24 |
1 | J:144181 Meng H, Lee VM, Differential expression of sphingosine-1-phosphate receptors 1-5 in the developing nervous system. Dev Dyn. 2009 Feb;238(2):487-500 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
S1pr2 sphingosine-1-phosphate receptor 2 (Synonyms: 1100001A16Rik, Edg5, Gpcr13, H218, LPb2, S1P2) | |
Results | Reference |
1 | J:144181 Meng H, Lee VM, Differential expression of sphingosine-1-phosphate receptors 1-5 in the developing nervous system. Dev Dyn. 2009 Feb;238(2):487-500 |
1 | J:243381 Serafimidis I, Rodriguez-Aznar E, Lesche M, Yoshioka K, Takuwa Y, Dahl A, Pan D, Gavalas A, Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. PLoS Biol. 2017 Mar;15(3):e2000949 |
S1pr3 sphingosine-1-phosphate receptor 3 (Synonyms: Edg3, LPb3, S1P3) | |
Results | Reference |
1 | J:144181 Meng H, Lee VM, Differential expression of sphingosine-1-phosphate receptors 1-5 in the developing nervous system. Dev Dyn. 2009 Feb;238(2):487-500 |
S1pr4 sphingosine-1-phosphate receptor 4 (Synonyms: Edg6, lpC1, S1P4) | |
Results | Reference |
1 | J:144181 Meng H, Lee VM, Differential expression of sphingosine-1-phosphate receptors 1-5 in the developing nervous system. Dev Dyn. 2009 Feb;238(2):487-500 |
S1pr5 sphingosine-1-phosphate receptor 5 (Synonyms: Edg8, lpB4, S1P5) | |
Results | Reference |
1 | J:144181 Meng H, Lee VM, Differential expression of sphingosine-1-phosphate receptors 1-5 in the developing nervous system. Dev Dyn. 2009 Feb;238(2):487-500 |
S100a1 S100 calcium binding protein A1 (Synonyms: S100, S100a) | |
Results | Reference |
1* | J:66482 Kiewitz R, Lyons GE, Schafer BW, Heizmann CW, Transcriptional regulation of S100A1 and expression during mouse heart development. Biochim Biophys Acta. 2000 Dec 20;1498(2-3):207-19 |
2* | J:326663 Qasrawi F, Meuser M, Lehnhoff F, Schulte M, Kispert A, S100A1 expression characterizes terminally differentiated superficial cells in the urothelium of the murine bladder and ureter. Histochem Cell Biol. 2022 Jun 1; |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
S100a4 S100 calcium binding protein A4 (Synonyms: 18A2, 42a, calvasculin, Capl, CAPL, Fibroblast-specific protein 1, FSp1, metastasin, Mts1, PeL98, pk9a) | |
Results | Reference |
1 | J:205073 Cano E, Carmona R, Munoz-Chapuli R, Wt1-expressing progenitors contribute to multiple tissues in the developing lung. Am J Physiol Lung Cell Mol Physiol. 2013 Aug 15;305(4):L322-32 |
1 | J:70451 Ito M, Kizawa K, Expression of calcium-binding S100 proteins A4 and A6 in regions of the epithelial sac associated with the onset of hair follicle regeneration. J Invest Dermatol. 2001 Jun;116(6):956-63 |
1 | J:27240 Jackson-Grusby LL, Swiergiel J, Linzer DI, A growth-related mRNA in cultured mouse cells encodes a placental calcium binding protein. Nucleic Acids Res. 1987 Aug 25;15(16):6677-90 |
1 | J:173588 Kanazawa T, Ichii O, Otsuka S, Namiki Y, Hashimoto Y, Kon Y, Hepatocyte nuclear factor 4 alpha is associated with mesenchymal-epithelial transition in developing kidneys of C57BL/6 mice. J Vet Med Sci. 2011 May;73(5):601-7 |
1 | J:43267 Klingelhofer J, Ambartsumian NS, Lukanidin EM, Expression of the metastasis-associated mts1 gene during mouse development. Dev Dyn. 1997 Oct;210(2):87-95 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:340973 Wojahn I, Ludtke TH, Christoffels VM, Trowe MO, Kispert A, TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung. Respir Res. 2019 Dec 23;20(1):292 |
S100a5 S100 calcium binding protein A5 (Synonyms: S100D9) | |
Results | Reference |
1 | J:301112 Maddala R, Gao J, Mathias RT, Lewis TR, Arshavsky VY, Levine A, Backer JM, Bresnick AR, Rao PV, Absence of S100A4 in the mouse lens induces an aberrant retina-specific differentiation program and cataract. Sci Rep. 2021 Jan 26;11(1):2203 |
S100a6 S100 calcium binding protein A6 (calcyclin) (Synonyms: 2A9, 5B10, Cacy, CALCYCLIN, PRA) | |
Results | Reference |
2* | J:49624 Farnsworth RL, Talamantes F, Calcyclin in the mouse decidua: expression and effects on placental lactogen secretion. Biol Reprod. 1998 Sep;59(3):546-52 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:70451 Ito M, Kizawa K, Expression of calcium-binding S100 proteins A4 and A6 in regions of the epithelial sac associated with the onset of hair follicle regeneration. J Invest Dermatol. 2001 Jun;116(6):956-63 |
1 | J:95925 Park YK, Franklin JL, Settle SH, Levy SE, Chung E, Jeyakumar LH, Shyr Y, Washington MK, Whitehead RH, Aronow BJ, Coffey RJ, Gene expression profile analysis of mouse colon embryonic development. Genesis. 2005 Jan;41(1):1-12 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
S100a8 S100 calcium binding protein A8 (calgranulin A) (Synonyms: 60B8Ag, B8Ag, Caga, CFAg, CP-10, MRP8, p8) | |
Results | Reference |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
S100a9 S100 calcium binding protein A9 (calgranulin B) (Synonyms: 60B8Ag, BEE22, Cagb, GAGB, L1Ag, MRP14, p14) | |
Results | Reference |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1 | J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39 |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
1 | J:114626 Yu Z, Lin KK, Bhandari A, Spencer JA, Xu X, Wang N, Lu Z, Gill GN, Roop DR, Wertz P, Andersen B, The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Dev Biol. 2006 Nov 1;299(1):122-36 |
S100a11 S100 calcium binding protein A11 (Synonyms: cal, calgizzarin, Emap1, S100a14, S100c) | |
Results | Reference |
2* | J:57920 Kraszucka K, Burfeind P, Nayernia K, Kohler M, Schmid M, Yaylaoglu M, Engel W, Developmental stage- and germ cell-regulated expression of a calcium-binding protein mRNA in mouse Sertoli cells. Mol Reprod Dev. 1999 Nov;54(3):232-43 |
S100a16 S100 calcium binding protein A16 (Synonyms: 2300002L21Rik) | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
S100b S100 protein, beta polypeptide, neural | |
Results | Reference |
1* | J:130196 Alfonsi F, Filippi P, Salaun D, deLapeyriere O, Durbec P, LIFR beta plays a major role in neuronal identity determination and glial differentiation in the mouse facial nucleus. Dev Biol. 2008 Jan 1;313(1):267-78 |
1* | J:199435 Barraud P, St John JA, Stolt CC, Wegner M, Baker CV, Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Biol Open. 2013 Jul 15;2(7):750-9 |
1 | J:199451 Brunne B, Franco S, Bouche E, Herz J, Howell BW, Pahle J, Muller U, May P, Frotscher M, Bock HH, Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by reelin signaling mutant mice. Glia. 2013 Aug;61(8):1347-63 |
1 | J:313341 Comer JD, Pan FC, Willet SG, Haldipur P, Millen KJ, Wright CV, Kaltschmidt JA, Sensory and spinal inhibitory dorsal midline crossing is independent of Robo3. Front Neural Circuits. 2015;9:36 |
1 | J:311541 Du J, Yi M, Zhou F, He W, Yang A, Qiu M, Huang H, S100B is selectively expressed by gray matter protoplasmic astrocytes and myelinating oligodendrocytes in the developing CNS. Mol Brain. 2021 Oct 6;14(1):154 |
1 | J:229100 Goto M, Hojo M, Ando M, Kita A, Kitagawa M, Ohtsuka T, Kageyama R, Miyamoto S, Hes1 and Hes5 are required for differentiation of pituicytes and formation of the neurohypophysis in pituitary development. Brain Res. 2015 Nov 2;1625:206-17 |
1* | J:269500 Hao MM, Capoccia E, Cirillo C, Boesmans W, Vanden Berghe P, Arundic Acid Prevents Developmental Upregulation of S100B Expression and Inhibits Enteric Glial Development. Front Cell Neurosci. 2017;11:42 |
1 | J:332402 Hockman D, Adameyko I, Kaucka M, Barraud P, Otani T, Hunt A, Hartwig AC, Sock E, Waithe D, Franck MCM, Ernfors P, Ehinger S, Howard MJ, Brown N, Reese J, Baker CVH, Striking parallels between carotid body glomus cell and adrenal chromaffin cell development. Dev Biol. 2018 Dec 1;444 Suppl 1(Suppl 1):S308-S324 |
1* | J:346057 Lu D, Zhi Y, Su H, Lin X, Lin J, Shi Y, Yi W, Hong C, Zhang T, Fu Z, Chen LY, Zhao Z, Li R, Xu Z, Chen W, Wang N, Xu D, ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells. Cell Rep. 2024 Feb 24;43(3):113818 |
1 | J:95755 Maka M, Stolt CC, Wegner M, Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect. Dev Biol. 2005 Jan 1;277(1):155-69 |
1 | J:333797 Min KW, Kim N, Lee JH, Sung Y, Kim M, Lee EJ, Kim JM, Kim JH, Lee J, Cho W, Yang JM, Kim N, Kim J, Lee CJ, Park YG, Lee SH, Lee HW, Kim JW, Visuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant. Exp Mol Med. 2023 Feb;55(2):385-400 |
1 | J:269506 Minocha S, Valloton D, Brunet I, Eichmann A, Hornung JP, Lebrand C, NG2 glia are required for vessel network formation during embryonic development. Elife. 2015 Dec 10;4:e09102 |
1 | J:182762 Mundell NA, Plank JL, LeGrone AW, Frist AY, Zhu L, Shin MK, Southard-Smith EM, Labosky PA, Enteric nervous system specific deletion of Foxd3 disrupts glial cell differentiation and activates compensatory enteric progenitors. Dev Biol. 2012 Mar 15;363(2):373-87 |
1 | J:205632 Saito A, Kanemoto S, Kawasaki N, Asada R, Iwamoto H, Oki M, Miyagi H, Izumi S, Sanosaka T, Nakashima K, Imaizumi K, Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun. 2012;3:967 |
1 | J:84301 Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M, The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 2003 Jul 1;17(13):1677-89 |
S100g S100 calcium binding protein G (Synonyms: CABP1, Cabp9k, CaBP-D9K, Calb3, Calbindin D9k) | |
Results | Reference |
1 | J:50421 Alcantara S, Ruiz M, D'Arcangelo G, Ezan F, de Lecea L, Curran T , Sotelo C , Soriano E, Regional and cellular patterns of reelin mRNA expression in the forebrain of the developing and adult mouse. J Neurosci. 1998 Oct 1;18(19):7779-99 |
1 | J:99635 Legaz I, Olmos L, Real MA, Guirado S, Davila JC, Medina L, Development of neurons and fibers containing calcium binding proteins in the pallial amygdala of mouse, with special emphasis on those of the basolateral amygdalar complex. J Comp Neurol. 2005 Aug 8;488(4):492-513 |
Saa2 serum amyloid A 2 (Synonyms: Saa-2) | |
Results | Reference |
1* | J:148705 Kelly KJ, Kluve-Beckerman B, Dominguez JH, Acute-phase response protein serum amyloid A stimulates renal tubule formation: studies in vitro and in vivo. Am J Physiol Renal Physiol. 2009 Jun;296(6):F1355-63 |
Sae1 SUMO1 activating enzyme subunit 1 (Synonyms: 2400010M20Rik, 2610044L12Rik, AOS1, D7Ertd177e, HSPC140, SUMO-1 activating enzyme subunit 1, Uble1a) | |
Results | Reference |
1* | J:356303 Zhao Y, Zheng D, Cvekl A, A comprehensive spatial-temporal transcriptomic analysis of differentiating nascent mouse lens epithelial and fiber cells. Exp Eye Res. 2018 Oct;175:56-72 |
Sall1 spalt like transcription factor 1 (Synonyms: Msal-3) | |
Results | Reference |
1 | J:278104 Acebedo AR, Suzuki K, Hino S, Alcantara MC, Sato Y, Haga H, Matsumoto KI, Nakao M, Shimamura K, Takeo T, Nakagata N, Miyagawa S, Nishinakamura R, Adelstein RS, Yamada G, Mesenchymal actomyosin contractility is required for androgen-driven urethral masculinization in mice. Commun Biol. 2019;2:95 |
1 | J:331894 Alcantara MC, Suzuki K, Acebedo AR, Kajioka D, Hirohata S, Kaisho T, Hatano Y, Yamagata K, Takahashi S, Yamada G, Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice. iScience. 2022 Dec 22;25(12):105609 |
1* | J:290791 Baba Y, Watabe Y, Sagara H, Watanabe S, Sall1 plays pivotal roles for lens fiber cell differentiation in mouse. Biochem Biophys Res Commun. 2019 May 14;512(4):927-933 |
1 | J:109774 Roy K, Kuznicki K, Wu Q, Sun Z, Bock D, Schutz G, Vranich N, Monaghan AP, The Tlx gene regulates the timing of neurogenesis in the cortex. J Neurosci. 2004 Sep 22;24(38):8333-45 |
1 | J:225537 Zhang J, Taylor RJ, La Torre A, Wilken MS, Cox KE, Reh TA, Vetter ML, Ezh2 maintains retinal progenitor proliferation, transcriptional integrity, and the timing of late differentiation. Dev Biol. 2015 Jul 15;403(2):128-38 |
Sall2 spalt like transcription factor 2 (Synonyms: mKIAA0360, Msal-2) | |
Results | Reference |
1* | J:59254 Kohlhase J, Altmann M, Archangelo L, Dixkens C, Engel W, Genomic cloning, chromosomal mapping, and expression analysis of msal-2. Mamm Genome. 2000 Jan;11(1):64-8 |
Sall3 spalt like transcription factor 3 (Synonyms: B130022O04Rik, Msal, Msal-1, Salt, Spalt) | |
Results | Reference |
1 | J:173617 de Melo J, Peng GH, Chen S, Blackshaw S, The Spalt family transcription factor Sall3 regulates the development of cone photoreceptors and retinal horizontal interneurons. Development. 2011 Jun;138(11):2325-36 |
1 | J:314124 Gao Y, Duque-Wilckens N, Aljazi MB, Wu Y, Moeser AJ, Mias GI, Robison AJ, He J, Loss of histone methyltransferase ASH1L in the developing mouse brain causes autistic-like behaviors. Commun Biol. 2021 Jun 18;4(1):756 |
1* | J:137254 Harrison SJ, Parrish M, Monaghan AP, Sall3 is required for the terminal maturation of olfactory glomerular interneurons. J Comp Neurol. 2008 Apr 10;507(5):1780-94 |
1* | J:33754 Ott T, Kaestner KH, Monaghan AP, Schutz G, The mouse homolog of the region specific homeotic gene spalt of Drosophila is expressed in the developing nervous system and in mesoderm-derived structures. Mech Dev. 1996 May;56(1-2):117-28 |
1 | J:92241 Parrish M, Ott T, Lance-Jones C, Schuetz G, Schwaeger-Nickolenko A, Monaghan AP, Loss of the Sall3 gene leads to palate deficiency, abnormalities in cranial nerves, and perinatal lethality. Mol Cell Biol. 2004 Aug;24(16):7102-12 |
1 | J:131661 Rizzolio F, Bione S, Sala C, Tribioli C, Ciccone R, Zuffardi O, di Iorgi N, Maghnie M, Toniolo D, Highly conserved non-coding sequences and the 18q critical region for short stature: a common mechanism of disease?. PLoS One. 2008;3(1):e1460 |
1 | J:109774 Roy K, Kuznicki K, Wu Q, Sun Z, Bock D, Schutz G, Vranich N, Monaghan AP, The Tlx gene regulates the timing of neurogenesis in the cortex. J Neurosci. 2004 Sep 22;24(38):8333-45 |
Sall4 spalt like transcription factor 4 (Synonyms: 5730441M18Rik, C330011P20Rik, Tex20) | |
Results | Reference |
1 | J:316527 Chen HH, Welling M, Bloch DB, Munoz J, Mientjes E, Chen X, Tramp C, Wu J, Yabuuchi A, Chou YF, Buecker C, Krainer A, Willemsen R, Heck AJ, Geijsen N, DAZL limits pluripotency, differentiation, and apoptosis in developing primordial germ cells. Stem Cell Reports. 2014 Nov 11;3(5):892-904 |
Samd1 sterile alpha motif domain containing 1 | |
Results | Reference |
1* | J:333561 Campbell B, Weber LM, Engle SJ, Ozolins TRS, Bourassa P, Aiello R, Liefke R, Investigation of SAMD1 ablation in mice. Sci Rep. 2023 Feb 21;13(1):3000 |
Sap30 sin3 associated polypeptide (Synonyms: 30kDa) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Sapcd2 suppressor APC domain containing 2 (Synonyms: 2010317E24Rik, 6030458L21Rik, ang) | |
Results | Reference |
1* | J:94056 Murata T, Furushima K, Hirano M, Kiyonari H, Nakamura M, Suda Y, Aizawa S, ang is a novel gene expressed in early neuroectoderm, but its null mutant exhibits no obvious phenotype. Gene Expr Patterns. 2004 Dec;5(2):171-8 |
Sar1b secretion associated Ras related GTPase 1B (Synonyms: 2310075M17Rik, 2900019I22Rik, Sara2) | |
Results | Reference |
1* | J:299703 Li X, Yan M, Guo Z, Yan L, Feng R, Zhu H, Tu X, Yu S, Chen JG, Inhibition of Sar1b, the Gene Implicated in Chylomicron Retention Disease, Impairs Migration and Morphogenesis of Developing Cortical Neurons. Neuroscience. 2020 Nov 21;449:228-240 |
Sat1 spermidine/spermine N1-acetyl transferase 1 | |
Results | Reference |
1* | J:120114 Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY, A biphasic pattern of gene expression during mouse retina development. BMC Dev Biol. 2006;6:48 |
Satb1 special AT-rich sequence binding protein 1 (Synonyms: 2610306G12Rik) | |
Results | Reference |
2 | J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:354849 Wutikeli H, Yu Y, Zhang T, Cao J, Nawy S, Shen Y, Role of Elavl-like RNA-binding protein in retinal development and signal transduction. Biochim Biophys Acta Mol Basis Dis. 2024 Sep 20;1871(1):167518 |
Satb2 special AT-rich sequence binding protein 2 (Synonyms: BAP002, mKIAA1034) | |
Results | Reference |
1 | J:344365 Abad C, Robayo MC, Muniz-Moreno MDM, Bernardi MT, Otero MG, Kosanovic C, Griswold AJ, Pierson TM, Walz K, Young JI, Gatad2b, associated with the neurodevelopmental syndrome GAND, plays a critical role in neurodevelopment and cortical patterning. Transl Psychiatry. 2024 Jan 18;14(1):33 |
1 | J:314588 Ahmed M, Moon R, Prajapati RS, James E, Albert Basson M, Streit A, The chromatin remodelling factor Chd7 protects auditory neurons and sensory hair cells from stress-induced degeneration. Commun Biol. 2021 Nov 3;4(1):1260 |
1 | J:350469 Alderman PJ, Saxon D, Torrijos-Saiz LI, Sharief M, Page CE, Baroudi JK, Biagiotti SW, Butyrkin VA, Melamed A, Kuo CT, Vicini S, Garcia-Verdugo JM, Herranz-Perez V, Corbin JG, Sorrells SF, Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala. Neuron. 2024 Feb 21;112(4):574-592.e10 |
1 | J:178862 Alfano C, Viola L, Heng JI, Pirozzi M, Clarkson M, Flore G, De Maio A, Schedl A, Guillemot F, Studer M, COUP-TFI promotes radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression. Development. 2011 Nov;138(21):4685-97 |
1 | J:339612 Altounian M, Bellon A, Mann F, Neuronal miR-17-5p contributes to interhemispheric cortical connectivity defects induced by prenatal alcohol exposure. Cell Rep. 2023 Aug 22;42(9):113020 |
1 | J:299451 Atkins A, Xu MJ, Li M, Rogers NP, Pryzhkova MV, Jordan PW, SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. Elife. 2020 Nov 17;9:e61171 |
1 | J:305458 Bertacchi M, Romano AL, Loubat A, Tran Mau-Them F, Willems M, Faivre L, Khau van Kien P, Perrin L, Devillard F, Sorlin A, Kuentz P, Philippe C, Garde A, Neri F, Di Giaimo R, Oliviero S, Cappello S, D'Incerti L, Frassoni C, Studer M, NR2F1 regulates regional progenitor dynamics in the mouse neocortex and cortical gyrification in BBSOAS patients. EMBO J. 2020 Jul 1;39(13):e104163 |
1 | J:349721 Borisova E, Newman AG, Couce Iglesias M, Dannenberg R, Schaub T, Qin B, Rusanova A, Brockmann M, Koch J, Daniels M, Turko P, Jahn O, Kaplan DR, Rosario M, Iwawaki T, Spahn CMT, Rosenmund C, Meierhofer D, Kraushar ML, Tarabykin V, Ambrozkiewicz MC, Protein translation rate determines neocortical neuron fate. Nat Commun. 2024 Jun 7;15(1):4879 |
1 | J:135318 Britanova O, de Juan Romero C, Cheung A, Kwan KY, Schwark M, Gyorgy A, Vogel T, Akopov S, Mitkovski M, Agoston D, Sestan N, Molnar Z, Tarabykin V, Satb2 is a postmitotic determinant for upper-layer neuron specification in the neocortex. Neuron. 2008 Feb 7;57(3):378-92 |
1 | J:300487 Chai G, Webb A, Li C, Antaki D, Lee S, Breuss MW, Lang N, Stanley V, Anzenberg P, Yang X, Marshall T, Gaffney P, Wierenga KJ, Chung BH, Tsang MH, Pais LS, Lovgren AK, VanNoy GE, Rehm HL, Mirzaa G, Leon E, Diaz J, Neumann A, Kalverda AP, Manfield IW, Parry DA, Logan CV, Johnson CA, Bonthron DT, Valleley EMA, Issa MY, Abdel-Ghafar SF, Abdel-Hamid MS, Jennings P, Zaki MS, Sheridan E, Gleeson JG, Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 Jan 20;109(2):241-256.e9 |
1 | J:235552 Chinn GA, Hirokawa KE, Chuang TM, Urbina C, Patel F, Fong J, Funatsu N, Monuki ES, Agenesis of the Corpus Callosum Due to Defective Glial Wedge Formation in Lhx2 Mutant Mice. Cereb Cortex. 2015 Sep;25(9):2707-18 |
1 | J:192580 Diaz-Alonso J, Aguado T, Wu CS, Palazuelos J, Hofmann C, Garcez P, Guillemot F, Lu HC, Lutz B, Guzman M, Galve-Roperh I, The CB(1) cannabinoid receptor drives corticospinal motor neuron differentiation through the Ctip2/Satb2 transcriptional regulation axis. J Neurosci. 2012 Nov 21;32(47):16651-65 |
2 | J:115876 Dobreva G, Chahrour M, Dautzenberg M, Chirivella L, Kanzler B, Farinas I, Karsenty G, Grosschedl R, SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation. Cell. 2006 Jun 2;125(5):971-86 |
1 | J:272744 Fawal MA, Jungas T, Kischel A, Audouard C, Iacovoni JS, Davy A, Cross Talk between One-Carbon Metabolism, Eph Signaling, and Histone Methylation Promotes Neural Stem Cell Differentiation. Cell Rep. 2018 Jun 5;23(10):2864-2873.e7 |
1 | J:211816 Fei JF, Haffner C, Huttner WB, 3' UTR-dependent, miR-92-mediated restriction of Tis21 expression maintains asymmetric neural stem cell division to ensure proper neocortex size. Cell Rep. 2014 Apr 24;7(2):398-411 |
1 | J:269420 Franz H, Villarreal A, Heidrich S, Videm P, Kilpert F, Mestres I, Calegari F, Backofen R, Manke T, Vogel T, DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex. Nucleic Acids Res. 2019 Jan 10;47(1):168-183 |
1* | J:205524 Fujimori A, Itoh K, Goto S, Hirakawa H, Wang B, Kokubo T, Kito S, Tsukamoto S, Fushiki S, Disruption of Aspm causes microcephaly with abnormal neuronal differentiation. Brain Dev. 2014 Sep;36(8):661-9 |
1 | J:360819 Gabriel GC, Yagi H, Tan T, Bais A, Glennon BJ, Stapleton MC, Huang L, Reynolds WT, Shaffer MG, Ganapathiraju M, Simon D, Panigrahy A, Wu YL, Lo CW, Mitotic block and epigenetic repression underlie neurodevelopmental defects and neurobehavioral deficits in congenital heart disease. Nat Commun. 2025 Jan 7;16(1):469 |
1 | J:205533 Gallagher D, Norman AA, Woodard CL, Yang G, Gauthier-Fisher A, Fujitani M, Vessey JP, Cancino GI, Sachewsky N, Woltjen K, Fatt MP, Morshead CM, Kaplan DR, Miller FD, Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway. Cell Stem Cell. 2013 Nov 7;13(5):564-76 |
1 | J:179195 Georgala PA, Manuel M, Price DJ, The generation of superficial cortical layers is regulated by levels of the transcription factor Pax6. Cereb Cortex. 2011 Jan;21(1):81-94 |
1 | J:230652 Harb K, Magrinelli E, Nicolas CS, Lukianets N, Frangeul L, Pietri M, Sun T, Sandoz G, Grammont F, Jabaudon D, Studer M, Alfano C, Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications. Elife. 2016;5:e09531 |
2* | J:332929 Harnett D, Ambrozkiewicz MC, Zinnall U, Rusanova A, Borisova E, Drescher AN, Couce-Iglesias M, Villamil G, Dannenberg R, Imami K, Munster-Wandowski A, Fauler B, Mielke T, Selbach M, Landthaler M, Spahn CMT, Tarabykin V, Ohler U, Kraushar ML, A critical period of translational control during brain development at codon resolution. Nat Struct Mol Biol. 2022 Dec;29(12):1277-1290 |
1* | J:220612 Holmes G, van Bakel H, Zhou X, Losic B, Jabs EW, BCL11B expression in intramembranous osteogenesis during murine craniofacial suture development. Gene Expr Patterns. 2015 Jan;17(1):16-25 |
1* | J:289438 Kischel A, Audouard C, Fawal MA, Davy A, Ephrin-B2 paces neuronal production in the developing neocortex. BMC Dev Biol. 2020 May 13;20(1):12 |
1 | J:222255 Knock E, Pereira J, Lombard PD, Dimond A, Leaford D, Livesey FJ, Hendrich B, The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex. Neural Dev. 2015;10:13 |
1 | J:217604 Lavado A, Ware M, Pare J, Cao X, The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Development. 2014 Nov;141(21):4182-93 |
1 | J:235635 Leone DP, Heavner WE, Ferenczi EA, Dobreva G, Huguenard JR, Grosschedl R, McConnell SK, Satb2 Regulates the Differentiation of Both Callosal and Subcerebral Projection Neurons in the Developing Cerebral Cortex. Cereb Cortex. 2015 Oct;25(10):3406-19 |
1* | J:237748 Li X, Xiao J, Frohlich H, Tu X, Li L, Xu Y, Cao H, Qu J, Rappold GA, Chen JG, Foxp1 regulates cortical radial migration and neuronal morphogenesis in developing cerebral cortex. PLoS One. 2015;10(5):e0127671 |
1 | J:348287 Liang XG, Hoang K, Meyerink BL, Kc P, Paraiso K, Wang L, Jones IR, Zhang Y, Katzman S, Finn TS, Tsyporin J, Qu F, Chen Z, Visel A, Kriegstein A, Shen Y, Pilaz LJ, Chen B, A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex. Proc Natl Acad Sci U S A. 2024 May 14;121(20):e2321711121 |
3 | J:325428 Liu J, Yang M, Su M, Liu B, Zhou K, Sun C, Ba R, Yu B, Zhang B, Zhang Z, Fan W, Wang K, Zhong M, Han J, Zhao C, FOXG1 sequentially orchestrates subtype specification of postmitotic cortical projection neurons. Sci Adv. 2022 May 27;8(21):eabh3568 |
1* | J:346057 Lu D, Zhi Y, Su H, Lin X, Lin J, Shi Y, Yi W, Hong C, Zhang T, Fu Z, Chen LY, Zhao Z, Li R, Xu Z, Chen W, Wang N, Xu D, ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells. Cell Rep. 2024 Feb 24;43(3):113818 |
1 | J:322988 Markert F, Storch A, Hyperoxygenation During Mid-Neurogenesis Accelerates Cortical Development in the Fetal Mouse Brain. Front Cell Dev Biol. 2022;10:732682 |
1 | J:341276 Matrongolo MJ, Ho-Nguyen KT, Jain M, Ang PS, Reddy A, Schaper S, Tischfield MA, Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice. Development. 2023 Sep 15;150(18):dev201381 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:310398 Mire E, Hocine M, Bazellieres E, Jungas T, Davy A, Chauvet S, Mann F, Developmental Upregulation of Ephrin-B1 Silences Sema3C/Neuropilin-1 Signaling during Post-crossing Navigation of Corpus Callosum Axons. Curr Biol. 2018 Jun 4;28(11):1768-1782.e4 |
1* | J:219340 Molyneaux BJ, Goff LA, Brettler AC, Chen HH, Brown JR, Hrvatin S, Rinn JL, Arlotta P, DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex. Neuron. 2015 Jan 21;85(2):275-88 |
1 | J:335191 Munz M, Bharioke A, Kosche G, Moreno-Juan V, Brignall A, Rodrigues TM, Graff-Meyer A, Ulmer T, Haeuselmann S, Pavlinic D, Ledergerber N, Gross-Scherf B, Rozsa B, Krol J, Picelli S, Cowan CS, Roska B, Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex. Cell. 2023 Apr 27;186(9):1930-1949.e31 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1 | J:353047 Nevorankova P, Sulcova M, Kavkova M, Zimcik D, Balkova SM, Peleskova K, Kristekova D, Jakesova V, Zikmund T, Kaiser J, Hola LI, Kolar M, Buchtova M, Region-specific gene expression profiling of early mouse mandible uncovered SATB2 as a key molecule for teeth patterning. Sci Rep. 2024 Aug 6;14(1):18212 |
1 | J:330578 Qian X, DeGennaro EM, Talukdar M, Akula SK, Lai A, Shao DD, Gonzalez D, Marciano JH, Smith RS, Hylton NK, Yang E, Bazan JF, Barrett L, Yeh RC, Hill RS, Beck SG, Otani A, Angad J, Mitani T, Posey JE, Pehlivan D, Calame D, Aydin H, Yesilbas O, Parks KC, Argilli E, England E, Im K, Taranath A, Scott HS, Barnett CP, Arts P, Sherr EH, Lupski JR, Walsh CA, Loss of non-motor kinesin KIF26A causes congenital brain malformations via dysregulated neuronal migration and axonal growth as well as apoptosis. Dev Cell. 2022 Oct 24;57(20):2381-2396.e13 |
1 | J:353313 Roussat M, Jungas T, Audouard C, Omerani S, Medevielle F, Agius E, Davy A, Pituello F, Bel-Vialar S, Control of G(2) Phase Duration by CDC25B Modulates the Switch from Direct to Indirect Neurogenesis in the Neocortex. J Neurosci. 2023 Feb 15;43(7):1154-1165 |
1 | J:341708 Saha S, Jungas TT, Ohayon D, Audouard C, Ye T, Fawal MA, Davy A, Dihydrofolate reductase activity controls neurogenic transitions in the developing neocortex. Development. 2023 Oct 15;150(20):dev201696 |
1* | J:291094 Sheikh BN, Guhathakurta S, Tsang TH, Schwabenland M, Renschler G, Herquel B, Bhardwaj V, Holz H, Stehle T, Bondareva O, Aizarani N, Mossad O, Kretz O, Reichardt W, Chatterjee A, Braun LJ, Thevenon J, Sartelet H, Blank T, Grun D, von Elverfeldt D, Huber TB, Vestweber D, Avilov S, Prinz M, Buescher JM, Akhtar A, Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nat Cell Biol. 2020 Jul;22(7):828-841 |
1* | J:324710 Stanton-Turcotte D, Hsu K, Moore SA, Yamada M, Fawcett JP, Iulianella A, Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development. J Neurosci. 2022 May 11;42(19):3931-3948 |
1 | J:298594 Stepien BK, Naumann R, Holtz A, Helppi J, Huttner WB, Vaid S, Lengthening Neurogenic Period during Neocortical Development Causes a Hallmark of Neocortex Expansion. Curr Biol. 2020 Nov 2;30(21):4227-4237.e5 |
1 | J:278287 Tang T, Zhang Y, Wang Y, Cai Z, Lu Z, Li L, Huang R, Hagelkruys A, Matthias P, Zhang H, Seiser C, Xie Y, HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development. Neuron. 2019 Mar 20;101(6):1117-1133.e5 |
1* | J:305372 Tian H, She Z, Gao X, Wang W, Tian H, MicroRNA-31 regulates dental epithelial cell proliferation by targeting Satb2. Biochem Biophys Res Commun. 2020 Nov 5;532(2):321-328 |
1 | J:343099 Tonosaki M, Fujimori A, Yaoi T, Itoh K, Loss of Aspm causes increased apoptosis of developing neural cells during mouse cerebral corticogenesis. PLoS One. 2023;18(11):e0294893 |
1 | J:304564 Venkataramanappa S, Schutz D, Saaber F, Kumar PA, Abe P, Schulz S, Stumm R, The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS Genet. 2021 Mar;17(3):e1009441 |
1* | J:316179 Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y, An epigenetic circuit controls neurogenic programs during neocortex development. Development. 2021;148:dev199772 |
1 | J:177905 Yamasaki T, Kawasaki H, Arakawa S, Shimizu K, Shimizu S, Reiner O, Okano H, Nishina S, Azuma N, Penninger JM, Katada T, Nishina H, Stress-Activated Protein Kinase MKK7 Regulates Axon Elongation in the Developing Cerebral Cortex. J Neurosci. 2011 Nov 16;31(46):16872-16883 |
1 | J:296696 Zhang L, Song NN, Zhang Q, Mei WY, He CH, Ma P, Huang Y, Chen JY, Mao B, Lang B, Ding YQ, Satb2 is required for the regionalization of retrosplenial cortex. Cell Death Differ. 2020 May;27(5):1604-1617 |
1 | J:312485 Zhang Q, Zhang L, Huang Y, Ma P, Mao B, Ding YQ, Song NN, Satb2 regulates the development of dopaminergic neurons in the arcuate nucleus by Dlx1. Cell Death Dis. 2021 Sep 25;12(10):879 |
1 | J:328995 Zhang SF, Dai SK, Du HZ, Wang H, Li XG, Tang Y, Liu CM, The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis. Stem Cell Reports. 2022 Sep 13;17(9):2064-2080 |
Saxo2 stabilizer of axonemal microtubules 2 (Synonyms: 1700129I04Rik, Fam154b) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Sbsn suprabasin (Synonyms: 1110005D19Rik) | |
Results | Reference |
1* | J:119780 Bazzi H, Fantauzzo KA, Richardson GD, Jahoda CA, Christiano AM, Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression. Dev Dyn. 2007 Mar 1;236(4):961-970 |
2 | J:91898 Moffatt P, Salois P, St-Amant N, Gaumond MH, Lanctot C, Identification of a conserved cluster of skin-specific genes encoding secreted proteins. Gene. 2004 Jun 9;334:123-31 |
1* | J:296400 Nakazawa S, Shimauchi T, Funakoshi A, Aoshima M, Phadungsaksawasdi P, Sakabe JI, Asakawa S, Hirasawa N, Ito T, Tokura Y, Suprabasin-null mice retain skin barrier function and show high contact hypersensitivity to nickel upon oral nickel loading. Sci Rep. 2020 Sep 3;10(1):14559 |
Scap SREBF chaperone | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
3 | J:264124 Tsushima H, Tang YJ, Puviindran V, Hsu SC, Nadesan P, Yu C, Zhang H, Mirando AJ, Hilton MJ, Alman BA, Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis. Development. 2018 Jul 9;145(13):dev162396 |
Scaper S phase cyclin A-associated protein in the ER (Synonyms: D530014O03Rik, Zfp291) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Scara5 scavenger receptor class A, member 5 (Synonyms: 4932433F15Rik, 4933425F03Rik) | |
Results | Reference |
1* | J:102851 Sarraj MA, McClive PJ, Wilmore HP, Loveland KL, Sinclair AH, Novel scavenger receptor gene is differentially expressed in the embryonic and adult mouse testis. Dev Dyn. 2005 Dec;234(4):1026-33 |
Scarb1 scavenger receptor class B, member 1 (Synonyms: Cd36l1, Chohd1, Chohd1, Cla-1, D5Ertd460e, Hdlq1, Hlb398, Srb1, SR-BI, SRBI) | |
Results | Reference |
1 | J:57052 Cao G, Zhao L, Stangl H, Hasegawa T, Richardson JA, Parker KL, Hobbs HH, Developmental and hormonal regulation of murine scavenger receptor, class B, type 1. Mol Endocrinol. 1999 Sep;13(9):1460-73 |
Scd1 stearoyl-Coenzyme A desaturase 1 (Synonyms: SCD, Scd-1, stearoyl-CoA desaturase) | |
Results | Reference |
2 | J:200565 Antony N, Weir JR, McDougall AR, Mantamadiotis T, Meikle PJ, Cole TJ, Bird AD, cAMP response element binding protein1 is essential for activation of steroyl co-enzyme a desaturase 1 (Scd1) in mouse lung type II epithelial cells. PLoS One. 2013;8(4):e59763 |
1* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
Scd2 stearoyl-Coenzyme A desaturase 2 (Synonyms: Scd-2) | |
Results | Reference |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
Scg2 secretogranin II (Synonyms: Chgc, SgII) | |
Results | Reference |
1* | J:329933 Akkuratova N, Faure L, Kameneva P, Kastriti ME, Adameyko I, Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics. Front Endocrinol (Lausanne). 2022;13:1020000 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Scg3 secretogranin III (Synonyms: 1B1075, Chgd, SgIII) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1* | J:281311 Nakano Y, Wiechert S, Banfi B, Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8 |
1 | J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12) |
Scgb1a1 secretoglobin, family 1A, member 1 (Synonyms: Blastokinin, CC10, CC16, CCSP, club cell secretory protein, PCB-BP, UG, Utg) | |
Results | Reference |
1 | J:180979 Besnard V, Wert SE, Ikegami M, Xu Y, Heffner C, Murray SA, Donahue LR, Whitsett JA, Maternal synchronization of gestational length and lung maturation. PLoS One. 2011;6(11):e26682 |
2* | J:104973 Besnard V, Wert SE, Kaestner KH, Whitsett JA, Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1. Am J Physiol Lung Cell Mol Physiol. 2005 Nov;289(5):L750-9 |
1* | J:171712 Bird AD, Flecknoe SJ, Tan KH, Olsson PF, Antony N, Mantamadiotis T, Hooper SB, Cole TJ, cAMP response element binding protein is required for differentiation of respiratory epithelium during murine development. PLoS One. 2011;6(3):e17843 |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1 | J:91818 Collins BJ, Kleeberger W, Ball DW, Notch in lung development and lung cancer. Semin Cancer Biol. 2004 Oct;14(5):357-64 |
1 | J:315450 Giridhar PV, Bell SM, Sridharan A, Rajavelu P, Kitzmiller JA, Na CL, Kofron M, Brandt EB, Ericksen M, Naren AP, Moon C, Khurana Hershey GK, Whitsett JA, Airway Epithelial KIF3A Regulates Th2 Responses to Aeroallergens. J Immunol. 2016 Dec 1;197(11):4228-4239 |
1 | J:270164 Guo M, Du Y, Gokey JJ, Ray S, Bell SM, Adam M, Sudha P, Perl AK, Deshmukh H, Potter SS, Whitsett JA, Xu Y, Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth. Nat Commun. 2019 Jan 3;10(1):37 |
1 | J:233686 Jia WJ, Jiang S, Tang QL, Shen D, Xue B, Ning W, Li CJ, Geranylgeranyl Diphosphate Synthase Modulates Fetal Lung Branching Morphogenesis Possibly through Controlling K-Ras Prenylation. Am J Pathol. 2016 Jun;186(6):1454-65 |
1 | J:81588 Kaplan F, Comber J, Sladek R, Hudson TJ, Muglia LJ, Macrae T, Gagnon S, Asada M, Brewer JA, Sweezey NB, The growth factor midkine is modulated by both glucocorticoid and retinoid in fetal lung development. Am J Respir Cell Mol Biol. 2003 Jan;28(1):33-41 |
2 | J:136676 Li H, Cho SN, Evans CM, Dickey BF, Jeong JW, DeMayo FJ, Cre-mediated recombination in mouse Clara cells. Genesis. 2008 Jun;46(6):300-7 |
1 | J:338836 Li Q, Jiao J, Heng Y, Lu Q, Zheng Y, Li H, Cai J, Mei M, Bao S, Prmt5 promotes ciliated cell specification of airway epithelial progenitors via transcriptional inhibition of Tp63. J Biol Chem. 2023 Jun 24;299(8):104964 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:316972 Mehta A, Dobersch S, Dammann RH, Bellusci S, Ilinskaya ON, Braun T, Barreto G, Validation of Tuba1a as appropriate internal control for normalization of gene expression analysis during mouse lung development. Int J Mol Sci. 2015 Feb 25;16(3):4492-511 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
2* | J:276140 Naizhen X, Kido T, Yokoyama S, Linnoila RI, Kimura S, Spatiotemporal Expression of Three Secretoglobin Proteins, SCGB1A1, SCGB3A1, and SCGB3A2, in Mouse Airway Epithelia. J Histochem Cytochem. 2019 Jun;67(6):453-463 |
1* | J:82365 Reynolds SD, Reynolds PR, Pryhuber GS, Finder JD, Stripp BR, Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways. Am J Respir Crit Care Med. 2002 Dec 1;166(11):1498-509 |
1 | J:185114 Reynolds SD, Zemke AC, Giangreco A, Brockway BL, Teisanu RM, Drake JA, Mariani T, Di PY, Taketo MM, Stripp BR, Conditional stabilization of beta-catenin expands the pool of lung stem cells. Stem Cells. 2008 May;26(5):1337-46 |
2 | J:217677 Snitow ME, Li S, Morley MP, Rathi K, Lu MM, Kadzik RS, Stewart KM, Morrisey EE, Ezh2 represses the basal cell lineage during lung endoderm development. Development. 2015 Jan 1;142(1):108-17 |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
1* | J:146829 Yamada W, Nagao K, Horikoshi K, Fujikura A, Ikeda E, Inagaki Y, Kakitani M, Tomizuka K, Miyazaki H, Suda T, Takubo K, Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun. 2009 Apr 10;381(3):453-8 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Scgb1b27 secretoglobin, family 1B, member 27 (Synonyms: Abp, Abpa, Abpa27, Sal-1, Tcp) | |
Results | Reference |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
Scgb3a1 secretoglobin, family 3A, member 1 (Synonyms: 1110030K16Rik, HIN-1, LuLeu2, UGRP2) | |
Results | Reference |
2* | J:276140 Naizhen X, Kido T, Yokoyama S, Linnoila RI, Kimura S, Spatiotemporal Expression of Three Secretoglobin Proteins, SCGB1A1, SCGB3A1, and SCGB3A2, in Mouse Airway Epithelia. J Histochem Cytochem. 2019 Jun;67(6):453-463 |
1* | J:79794 Niimi T, Copeland NG, Gilbert DJ, Jenkins NA, Srisodsai A, Zimonjic DB, Keck-Waggoner CL, Popescu NC, Kimura S, Cloning, expression, and chromosomal localization of the mouse gene (Scgb3a1, alias Ugrp2) that encodes a member of the novel uteroglobin-related protein gene family. Cytogenet Genome Res. 2002;97(1-2):120-7 |
1* | J:76819 Porter D, Lahti-Domenici J, Torres-Arzayus M, Chin L, Polyak K, Expression of high in normal-1 (HIN-1) and uteroglobin related protein-1 (UGRP-1) in adult and developing tissues. Mech Dev. 2002 Jun;114(1-2):201 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Scgb3a2 secretoglobin, family 3A, member 2 (Synonyms: LuLeu1, UGRP1) | |
Results | Reference |
2 | J:316183 Cai Y, Yoneda M, Tomita T, Kurotani R, Okamoto M, Kido T, Abe H, Mitzner W, Guha A, Kimura S, Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice. BMC Pulm Med. 2015 Jul 16;15:72 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:308704 Kiyokawa H, Yamaoka A, Matsuoka C, Tokuhara T, Abe T, Morimoto M, Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfbeta-Id2 axis, for tissue regeneration. Dev Cell. 2021 Jul 12;56(13):1917-1929.e9 |
2* | J:276140 Naizhen X, Kido T, Yokoyama S, Linnoila RI, Kimura S, Spatiotemporal Expression of Three Secretoglobin Proteins, SCGB1A1, SCGB3A1, and SCGB3A2, in Mouse Airway Epithelia. J Histochem Cytochem. 2019 Jun;67(6):453-463 |
1* | J:72388 Niimi T, Keck-Waggoner CL, Popescu NC, Zhou Y, Levitt RC, Kimura S, UGRP1, a Uteroglobin/Clara Cell Secretory Protein-Related Protein, Is a Novel Lung-Enriched Downstream Target Gene for the T/EBP/NKX2.1 Homeodomain Transcription Factor. Mol Endocrinol. 2001 Nov;15(11):2021-36 |
1* | J:76819 Porter D, Lahti-Domenici J, Torres-Arzayus M, Chin L, Polyak K, Expression of high in normal-1 (HIN-1) and uteroglobin related protein-1 (UGRP-1) in adult and developing tissues. Mech Dev. 2002 Jun;114(1-2):201 |
1* | J:82365 Reynolds SD, Reynolds PR, Pryhuber GS, Finder JD, Stripp BR, Secretoglobins SCGB3A1 and SCGB3A2 define secretory cell subsets in mouse and human airways. Am J Respir Crit Care Med. 2002 Dec 1;166(11):1498-509 |
1* | J:141842 Tomita T, Kido T, Kurotani R, Iemura S, Sterneck E, Natsume T, Vinson C, Kimura S, CAATT/enhancer-binding proteins alpha and delta interact with NKX2-1 to synergistically activate mouse secretoglobin 3A2 gene expression. J Biol Chem. 2008 Sep 12;283(37):25617-27 |
1 | J:353791 Xu L, Tan C, Barr J, Talaba N, Verheyden J, Chin JS, Gaboyan S, Kasaraneni N, Elgamal RM, Gaulton KJ, Lin G, Afshar K, Golts E, Meier A, Alexander LEC, Borok Z, Shen Y, Chung WK, McCulley DJ, Sun X, Context-dependent roles of mitochondrial LONP1 in orchestrating the balance between airway progenitor versus progeny cells. Cell Stem Cell. 2024 Aug 16; |
Scgn secretagogin, EF-hand calcium binding protein (Synonyms: MGC:27615) | |
Results | Reference |
1* | J:163028 Mulder J, Spence L, Tortoriello G, Dinieri JA, Uhlen M, Shui B, Kotlikoff MI, Yanagawa Y, Aujard F, Hokfelt T, Hurd YL, Harkany T, Secretagogin is a Ca2+-binding protein identifying prospective extended amygdala neurons in the developing mammalian telencephalon. Eur J Neurosci. 2010 Jun;31(12):2166-77 |
1* | J:262512 Raju CS, Spatazza J, Stanco A, Larimer P, Sorrells SF, Kelley KW, Nicholas CR, Paredes MF, Lui JH, Hasenstaub AR, Kriegstein AR, Alvarez-Buylla A, Rubenstein JL, Oldham MC, Secretagogin is Expressed by Developing Neocortical GABAergic Neurons in Humans but not Mice and Increases Neurite Arbor Size and Complexity. Cereb Cortex. 2018 Jun 1;28(6):1946-1958 |
Scin scinderin (Synonyms: adseverin) | |
Results | Reference |
1 | J:56669 Arai M, Kwiatkowski DJ, Differential developmentally regulated expression of gelsolin family members in the mouse. Dev Dyn. 1999 Aug;215(4):297-307 |
Scn2a sodium channel, voltage-gated, type II, alpha (Synonyms: A230052E19Rik, Nav1.2, Scn2a1) | |
Results | Reference |
1 | J:98945 Ballas N, Grunseich C, Lu DD, Speh JC, Mandel G, REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell. 2005 May 20;121(4):645-57 |
1 | J:268565 Ogiwara I, Miyamoto H, Tatsukawa T, Yamagata T, Nakayama T, Atapour N, Miura E, Mazaki E, Ernst SJ, Cao D, Ohtani H, Itohara S, Yanagawa Y, Montal M, Yuzaki M, Inoue Y, Hensch TK, Noebels JL, Yamakawa K, Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice. Commun Biol. 2018;1 |
Scn3b sodium channel, voltage-gated, type III, beta (Synonyms: 1110001K16Rik, 4833414B02Rik) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1 | J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12) |
Scn5a sodium channel, voltage-gated, type V, alpha (Synonyms: mH1, Nav1.5, Nav1.5c, SkM2) | |
Results | Reference |
1 | J:280846 Bezzina CR, Barc J, Mizusawa Y, Remme CA, Gourraud JB, Simonet F, Verkerk AO, Schwartz PJ, Crotti L, Dagradi F, Guicheney P, Fressart V, Leenhardt A, Antzelevitch C, Bartkowiak S, Borggrefe M, Schimpf R, Schulze-Bahr E, Zumhagen S, Behr ER, Bastiaenen R, Tfelt-Hansen J, Olesen MS, Kaab S, Beckmann BM, Weeke P, Watanabe H, Endo N, Minamino T, Horie M, Ohno S, Hasegawa K, Makita N, Nogami A, Shimizu W, Aiba T, Froguel P, Balkau B, Lantieri O, Torchio M, Wiese C, Weber D, Wolswinkel R, Coronel R, Boukens BJ, Bezieau S, Charpentier E, Chatel S, Despres A, Gros F, Kyndt F, Lecointe S, Lindenbaum P, Portero V, Violleau J, Gessler M, Tan HL, Roden DM, Christoffels VM, Le Marec H, Wilde AA, Probst V, Schott JJ, Dina C, Redon R, Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death. Nat Genet. 2013 Sep;45(9):1044-9 |
1 | J:250657 Greulich F, Trowe MO, Leffler A, Stoetzer C, Farin HF, Kispert A, Misexpression of Tbx18 in cardiac chambers of fetal mice interferes with chamber-specific developmental programs but does not induce a pacemaker-like gene signature. J Mol Cell Cardiol. 2016 Aug;97:140-9 |
Scn8a sodium channel, voltage-gated, type VIII, alpha (Synonyms: ataxia 3, C630029C19Rik, med, mnd-2, mnd2, motor end-plate disease, NaCh6, Nav1.6, nmf2, nmf335, NMF335, nmf58, nur14, seal) | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Scn9a sodium channel, voltage-gated, type IX, alpha (Synonyms: PN1) | |
Results | Reference |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
Scn10a sodium channel, voltage-gated, type X, alpha (Synonyms: Nav1.8) | |
Results | Reference |
1 | J:283226 Desiderio S, Vermeiren S, Van Campenhout C, Kricha S, Malki E, Richts S, Fletcher EV, Vanwelden T, Schmidt BZ, Henningfeld KA, Pieler T, Woods CG, Nagy V, Verfaillie C, Bellefroid EJ, Prdm12 Directs Nociceptive Sensory Neuron Development by Regulating the Expression of the NGF Receptor TrkA. Cell Rep. 2019 Mar 26;26(13):3522-3536.e5 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
Scn11a sodium channel, voltage-gated, type XI, alpha (Synonyms: NaN, NaT, NSS2, SNS2) | |
Results | Reference |
1 | J:326535 Petitpre C, Faure L, Uhl P, Fontanet P, Filova I, Pavlinkova G, Adameyko I, Hadjab S, Lallemend F, Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification. Nat Commun. 2022 Jul 5;13(1):3878 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
Scnn1a sodium channel, nonvoltage-gated 1 alpha (Synonyms: ENaC alpha, mENaC, Scnn1) | |
Results | Reference |
1 | J:183431 Aboudehen K, Hilliard S, Saifudeen Z, El-Dahr SS, Mechanisms of p53 activation and physiological relevance in the developing kidney. Am J Physiol Renal Physiol. 2012 Apr;302(8):F928-40 |
1* | J:42864 Dagenais A, Kothary R, Berthiaume Y, The alpha subunit of the epithelial sodium channel in the mouse: developmental regulation of its expression. Pediatr Res. 1997 Sep;42(3):327-34 |
1 | J:249431 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ, Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6:e26851 |
1* | J:107770 Nakamura K, Stokes JB, McCray PB Jr, Endogenous and exogenous glucocorticoid regulation of ENaC mRNA expression in developing kidney and lung. Am J Physiol Cell Physiol. 2002 Sep;283(3):C762-72 |
1* | J:151683 Parreira KS, Debaix H, Cnops Y, Geffers L, Devuyst O, Expression patterns of the aquaporin gene family during renal development: influence of genetic variability. Pflugers Arch. 2009 Aug;458(4):745-59 |
Scnn1b sodium channel, nonvoltage-gated 1 beta (Synonyms: ENaC beta) | |
Results | Reference |
1 | J:326201 Hayashi T, Eto K, Kadoya Y, Downregulation of ten-eleven translocation-2 triggers epithelial differentiation during organogenesis. Differentiation. 2022 May-Jun;125:45-53 |
1* | J:107770 Nakamura K, Stokes JB, McCray PB Jr, Endogenous and exogenous glucocorticoid regulation of ENaC mRNA expression in developing kidney and lung. Am J Physiol Cell Physiol. 2002 Sep;283(3):C762-72 |
Scnn1g sodium channel, nonvoltage-gated 1 gamma (Synonyms: ENaC gamma) | |
Results | Reference |
1* | J:329933 Akkuratova N, Faure L, Kameneva P, Kastriti ME, Adameyko I, Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics. Front Endocrinol (Lausanne). 2022;13:1020000 |
1* | J:107770 Nakamura K, Stokes JB, McCray PB Jr, Endogenous and exogenous glucocorticoid regulation of ENaC mRNA expression in developing kidney and lung. Am J Physiol Cell Physiol. 2002 Sep;283(3):C762-72 |
1 | J:231738 Reed-Geaghan EG, Wright MC, See LA, Adelman PC, Lee KH, Koerber HR, Maricich SM, Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. J Neurosci. 2016 Apr 13;36(15):4362-76 |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
Scpep1 serine carboxypeptidase 1 (Synonyms: 2410018F01Rik, 4833411K15Rik, Risc) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Scrib scribbled planar cell polarity (Synonyms: Crc, mKIAA0147, Scrb1) | |
Results | Reference |
2 | J:306225 Ezan J, Moreau MM, Mamo TM, Shimbo M, Decroo M, Richter M, Peyroutou R, Rachel R, Tissir F, de Anda FC, Sans N, Montcouquiol M, Early loss of Scribble affects cortical development, interhemispheric connectivity and psychomotor activity. Sci Rep. 2021 Apr 27;11(1):9106 |
1 | J:266265 Kishimoto K, Tamura M, Nishita M, Minami Y, Yamaoka A, Abe T, Shigeta M, Morimoto M, Synchronized mesenchymal cell polarization and differentiation shape the formation of the murine trachea and esophagus. Nat Commun. 2018 Jul 19;9(1):2816 |
1 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
1 | J:309456 Pearson HB, McGlinn E, Phesse TJ, Schluter H, Srikumar A, Godde NJ, Woelwer CB, Ryan A, Phillips WA, Ernst M, Kaur P, Humbert P, The polarity protein Scrib mediates epidermal development and exerts a tumor suppressive function during skin carcinogenesis. Mol Cancer. 2015 Sep 17;14:169 |
1 | J:178461 Pearson HB, Perez-Mancera PA, Dow LE, Ryan A, Tennstedt P, Bogani D, Elsum I, Greenfield A, Tuveson DA, Simon R, Humbert PO, SCRIB expression is deregulated in human prostate cancer, and its deficiency in mice promotes prostate neoplasia. J Clin Invest. 2011 Nov 1;121(11):4257-67 |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
1 | J:239794 Szymaniak AD, Mahoney JE, Cardoso WV, Varelas X, Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap. Dev Cell. 2015 Aug 10;34(3):283-96 |
1 | J:302296 Vong KI, Ma TC, Li B, Leung TCN, Nong W, Ngai SM, Hui JHL, Jiang L, Kwan KM, SOX9-COL9A3-dependent regulation of choroid plexus epithelial polarity governs blood-cerebrospinal fluid barrier integrity. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2009568118 |
Scrt1 scratch family zinc finger 1 | |
Results | Reference |
1 | J:197573 Itoh Y, Moriyama Y, Hasegawa T, Endo TA, Toyoda T, Gotoh Y, Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition-like mechanism. Nat Neurosci. 2013 Apr;16(4):416-25 |
Scrt2 scratch family zinc finger 2 | |
Results | Reference |
1 | J:197573 Itoh Y, Moriyama Y, Hasegawa T, Endo TA, Toyoda T, Gotoh Y, Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition-like mechanism. Nat Neurosci. 2013 Apr;16(4):416-25 |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
Sct secretin | |
Results | Reference |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
2* | J:95321 Siu FK, Sham MH, Chow BK, Secretin, a known gastrointestinal peptide, is widely expressed during mouse embryonic development. Gene Expr Patterns. 2005 Feb;5(3):445-51 |
Scube1 signal peptide, CUB domain, EGF-like 1 (Synonyms: 7330410C13Rik, A630023E24Rik) | |
Results | Reference |
1 | J:195784 Xavier GM, Panousopoulos L, Cobourne MT, Scube3 is expressed in multiple tissues during development but is dispensable for embryonic survival in the mouse. PLoS One. 2013;8(1):e55274 |
Scube2 signal peptide, CUB domain, EGF-like 2 (Synonyms: 4932442O19Rik, Cegf1, ICRFP703B1614Q5.1, ICRFP703N2430Q5.1) | |
Results | Reference |
1 | J:359451 Amato CM, Xu X, Yao HH, An extragenital cell population contributes to urethra closure during mouse penis development. Sci Adv. 2024 Dec 6;10(49):eadp0673 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1* | J:177203 Xavier GM, Cobourne MT, Scube2 expression extends beyond the central nervous system during mouse development. J Mol Histol. 2011 Oct;42(5):383-91 |
1 | J:195784 Xavier GM, Panousopoulos L, Cobourne MT, Scube3 is expressed in multiple tissues during development but is dispensable for embryonic survival in the mouse. PLoS One. 2013;8(1):e55274 |
Scube3 signal peptide, CUB domain, EGF-like 3 (Synonyms: D030038I21Rik) | |
Results | Reference |
1* | J:119915 Haworth K, Smith F, Zoupa M, Seppala M, Sharpe PT, Cobourne MT, Expression of the Scube3 epidermal growth factor-related gene during early embryonic development in the mouse. Gene Expr Patterns. 2007 Apr;7(5):630-634 |
1* | J:168645 Xavier GM, Economou A, Senna Guimaraes AL, Sharpe PT, Cobourne MT, Characterization of a mouse Scube3 reporter line. Genesis. 2010 Dec;48(12):684-92 |
1 | J:195784 Xavier GM, Panousopoulos L, Cobourne MT, Scube3 is expressed in multiple tissues during development but is dispensable for embryonic survival in the mouse. PLoS One. 2013;8(1):e55274 |
Scx scleraxis scleraxis bHLH transcription factor (Synonyms: bHLHa41, Scl) | |
Results | Reference |
1* | J:80873 Asou Y, Nifuji A, Tsuji K, Shinomiya K, Olson EN, Koopman P, Noda M, Coordinated expression of scleraxis and Sox9 genes during embryonic development of tendons and cartilage. J Orthop Res. 2002 Jul;20(4):827-33 |
1 | J:311884 Berthet E, Chen C, Butcher K, Schneider RA, Alliston T, Amirtharajah M, Smad3 binds Scleraxis and Mohawk and regulates tendon matrix organization. J Orthop Res. 2013 Sep;31(9):1475-83 |
1 | J:156015 Blitz E, Viukov S, Sharir A, Shwartz Y, Galloway JL, Pryce BA, Johnson RL, Tabin CJ, Schweitzer R, Zelzer E, Bone ridge patterning during musculoskeletal assembly is mediated through SCX regulation of Bmp4 at the tendon-skeleton junction. Dev Cell. 2009 Dec;17(6):861-73 |
1 | J:24330 Cserjesi P, Brown D, Ligon KL, Lyons GE, Copeland NG, Gilbert DJ, Jenkins NA, Olson EN, Scleraxis: a basic helix-loop-helix protein that prefigures skeletal formation during mouse embryogenesis. Development. 1995 Apr;121(4):1099-110 |
1 | J:160493 Dy P, Smits P, Silvester A, Penzo-Mendez A, Dumitriu B, Han Y, de la Motte CA, Kingsley DM, Lefebvre V, Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. Dev Biol. 2010 May 15;341(2):346-59 |
1 | J:272612 Eyal S, Rubin S, Krief S, Levin L, Zelzer E, Common cellular origin and diverging developmental programs for different sesamoid bones. Development. 2019 Feb 28;146(4):dev167452 |
1 | J:300927 Han X, Feng J, Guo T, Loh YE, Yuan Y, Ho TV, Cho CK, Li J, Jing J, Janeckova E, He J, Pei F, Bi J, Song B, Chai Y, Runx2-Twist1 interaction coordinates cranial neural crest guidance of soft palate myogenesis. Elife. 2021 Jan 22;10:e62387 |
1 | J:308781 Lejard V, Blais F, Guerquin MJ, Bonnet A, Bonnin MA, Havis E, Malbouyres M, Bidaud CB, Maro G, Gilardi-Hebenstreit P, Rossert J, Ruggiero F, Duprez D, EGR1 and EGR2 involvement in vertebrate tendon differentiation. J Biol Chem. 2011 Feb 18;286(7):5855-67 |
1 | J:155292 Levay AK, Peacock JD, Lu Y, Koch M, Hinton RB Jr, Kadler KE, Lincoln J, Scleraxis is required for cell lineage differentiation and extracellular matrix remodeling during murine heart valve formation in vivo. Circ Res. 2008 Oct 24;103(9):948-56 |
1* | J:307824 Liu H, Xu J, Lan Y, Lim HW, Jiang R, The Scleraxis Transcription Factor Directly Regulates Multiple Distinct Molecular and Cellular Processes During Early Tendon Cell Differentiation. Front Cell Dev Biol. 2021;9:654397 |
1* | J:356701 Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD, Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr;91(4):387-93 |
1 | J:354236 Wada S, Ideno H, Nakashima K, Komatsu K, Demura N, Tomonari H, Kimura H, Tachibana M, Nifuji A, The histone H3K9 methyltransferase G9a regulates tendon formation during development. Sci Rep. 2024 Sep 5;14(1):20771 |
1 | J:173585 Wang L, Bresee CS, Jiang H, He W, Ren T, Schweitzer R, Brigande JV, Scleraxis is Required for Differentiation of the Stapedius and Tensor Tympani Tendons of the Middle Ear. J Assoc Res Otolaryngol. 2011 Aug;12(4):407-21 |
1 | J:274387 Yoshimoto Y, Takimoto A, Watanabe H, Hiraki Y, Kondoh G, Shukunami C, Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system. Sci Rep. 2017 Mar 22;7:45010 |
Sdc1 syndecan 1 (Synonyms: CD138, syn-1, Synd, Synd1) | |
Results | Reference |
1 | J:191082 Clavel C, Grisanti L, Zemla R, Rezza A, Barros R, Sennett R, Mazloom AR, Chung CY, Cai X, Cai CL, Pevny L, Nicolis S, Ma'ayan A, Rendl M, Sox2 in the dermal papilla niche controls hair growth by fine-tuning BMP signaling in differentiating hair shaft progenitors. Dev Cell. 2012 Nov 13;23(5):981-94 |
1 | J:166772 DeRouen MC, Zhen H, Tan SH, Williams S, Marinkovich MP, Oro AE, Laminin-511 and integrin beta-1 in hair follicle development and basal cell carcinoma formation. BMC Dev Biol. 2010;10:112 |
1 | J:221161 Filatova A, Pagella P, Mitsiadis TA, Distribution of syndecan-1 protein in developing mouse teeth. Front Physiol. 2014;5:518 |
1 | J:83512 Hikake T, Mori T, Iseki K, Hagino S, Zhang Y, Takagi H, Yokoya S, Wanaka A, Comparison of expression patterns between CREB family transcription factor OASIS and proteoglycan core protein genes during murine tooth development. Anat Embryol (Berl). 2003 Apr;206(5):373-80 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:149989 Richardson GD, Bazzi H, Fantauzzo KA, Waters JM, Crawford H, Hynd P, Christiano AM, Jahoda CA, KGF and EGF signalling block hair follicle induction and promote interfollicular epidermal fate in developing mouse skin. Development. 2009 Jul;136(13):2153-64 |
1* | J:150758 Richardson GD, Fantauzzo KA, Bazzi H, Maatta A, Jahoda CA, Dynamic expression of Syndecan-1 during hair follicle morphogenesis. Gene Expr Patterns. 2009 Sep;9(6):454-60 |
1* | J:32188 Vainio S, Jalkanen M, Bernfield M, Saxen L, Transient expression of syndecan in mesenchymal cell aggregates of the embryonic kidney. Dev Biol. 1992 Aug;152(2):221-32 |
1 | J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10) |
Sdc2 syndecan 2 (Synonyms: 4833414L08Rik, fibroglycan, Hspg1, Synd2) | |
Results | Reference |
2 | J:196913 Bertrand J, Stange R, Hidding H, Echtermeyer F, Nalesso G, Godmann L, Timmen M, Bruckner P, Dell'Accio F, Raschke MJ, Pap T, Dreier R, Syndecan 4 supports bone fracture repair, but not fetal skeletal development, in mice. Arthritis Rheum. 2013 Mar;65(3):743-52 |
1 | J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10) |
Sdc3 syndecan 3 (Synonyms: MGC:65603, MGC:69616, mKIAA0468, syn-3, Synd3) | |
Results | Reference |
1 | J:83512 Hikake T, Mori T, Iseki K, Hagino S, Zhang Y, Takagi H, Yokoya S, Wanaka A, Comparison of expression patterns between CREB family transcription factor OASIS and proteoglycan core protein genes during murine tooth development. Anat Embryol (Berl). 2003 Apr;206(5):373-80 |
1 | J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10) |
Sdc4 syndecan 4 (Synonyms: ryudocan, S4, Synd4, syndecan-4) | |
Results | Reference |
1 | J:337768 Wishart TFL, Lovicu FJ, Spatiotemporal Localisation of Heparan Sulphate Proteoglycans throughout Mouse Lens Morphogenesis. Cells. 2023 May 11;12(10) |
Sdcbp syndecan binding protein (Synonyms: MDA-9, Sycl, syndecan interacting protein, syntenin, syntenin-1) | |
Results | Reference |
1* | J:195897 Jeon HY, Das SK, Dasgupta S, Emdad L, Sarkar D, Kim SH, Lee SG, Fisher PB, Expression patterns of MDA-9/syntenin during development of the mouse embryo. J Mol Histol. 2013 Apr;44(2):159-66 |
Sdccag8 serologically defined colon cancer antigen 8 (Synonyms: 2700048G21Rik, 5730470G24Rik, CCCAP) | |
Results | Reference |
1* | J:215665 Insolera R, Shao W, Airik R, Hildebrandt F, Shi SH, SDCCAG8 regulates pericentriolar material recruitment and neuronal migration in the developing cortex. Neuron. 2014 Aug 20;83(4):805-22 |
Sdha succinate dehydrogenase complex, subunit A, flavoprotein (Fp) (Synonyms: 2310034D06Rik, FP, SDH2, SDHF) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:216158 Rastetter RH, Bernard P, Palmer JS, Chassot AA, Chen H, Western PS, Ramsay RG, Chaboissier MC, Wilhelm D, Marker genes identify three somatic cell types in the fetal mouse ovary. Dev Biol. 2014 Oct 15;394(2):242-52 |
Sdhb succinate dehydrogenase complex, subunit B, iron sulfur (Ip) (Synonyms: 0710008N11Rik) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
1 | J:337469 Park A, Kim KE, Park I, Lee SH, Park KY, Jung M, Li X, Sleiman MB, Lee SJ, Kim DS, Kim J, Lim DS, Woo EJ, Lee EW, Han BS, Oh KJ, Lee SC, Auwerx J, Mun JY, Rhee HW, Kim WK, Bae KH, Suh JM, Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice. Nat Commun. 2023 Jun 23;14(1):3746 |
1* | J:305946 Xu M, Yao J, Shi Y, Yi H, Zhao W, Lin X, Yang Z, The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026 |
Sdk2 sidekick cell adhesion molecule 2 (Synonyms: 4632412F08Rik, 5330435L01Rik, mKIAA1514) | |
Results | Reference |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Sebox SEBOX homeobox (Synonyms: OG9, Og9x) | |
Results | Reference |
1* | J:63829 Cinquanta M, Rovescalli AC, Kozak CA, Nirenberg M, Mouse Sebox homeobox gene expression in skin, brain, oocytes, and two-cell embryos. Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):8904-9 |
1* | J:191898 Moreno DL, Salazar Z, Betancourt M, Casas E, Ducolomb Y, Gonzalez C, Bonilla E, Sebox plays an important role during the early mouse oogenesis in vitro. Zygote. 2012 Jul 18;:1-5 |
Sec22c SEC22 homolog C, vesicle trafficking protein (Synonyms: 5930407I15Rik, Sec22l3) | |
Results | Reference |
1* | J:245876 Rohacek AM, Bebee TW, Tilton RK, Radens CM, McDermott-Roe C, Peart N, Kaur M, Zaykaner M, Cieply B, Musunuru K, Barash Y, Germiller JA, Krantz ID, Carstens RP, Epstein DJ, ESRP1 Mutations Cause Hearing Loss due to Defects in Alternative Splicing that Disrupt Cochlear Development. Dev Cell. 2017 Nov 06;43(3):318-331.e5 |
Sec23a SEC23 homolog A, COPII coat complex component (Synonyms: Msec23, Sec23r) | |
Results | Reference |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
Sec24c SEC24 homolog C, COPII coat complex component (Synonyms: 2610204K03Rik, mKIAA0079) | |
Results | Reference |
2 | J:265679 Wang B, Joo JH, Mount R, Teubner BJW, Krenzer A, Ward AL, Ichhaporia VP, Adams EJ, Khoriaty R, Peters ST, Pruett-Miller SM, Zakharenko SS, Ginsburg D, Kundu M, The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018 Aug 1;128(8):3319-3332 |
Sec63 SEC63 homolog, protein translocation regulator (Synonyms: 5730478J10Rik) | |
Results | Reference |
1 | J:125042 Pierreux CE, Poll AV, Kemp CR, Clotman F, Maestro MA, Cordi S, Ferrer J, Leyns L, Rousseau GG, Lemaigre FP, The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse. Gastroenterology. 2006 Feb;130(2):532-41 |
Sectm1a secreted and transmembrane 1A (Synonyms: MGC:7970) | |
Results | Reference |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Sel1l sel-1 suppressor of lin-12-like (C. elegans) (Synonyms: Sel1h) | |
Results | Reference |
1 | J:255072 Cardano M, Diaferia GR, Conti L, Baronchelli S, Sessa A, Broccoli V, Barbieri A, De Blasio P, Biunno I, mSEL-1L deficiency affects vasculogenesis and neural stem cell lineage commitment. J Cell Physiol. 2018 Apr;233(4):3152-3163 |
1 | J:209744 Diaferia GR, Cirulli V, Biunno I, SEL1L regulates adhesion, proliferation and secretion of insulin by affecting integrin signaling. PLoS One. 2013;8(11):e79458 |
Sel1l3 sel-1 suppressor of lin-12-like 3 (C. elegans) (Synonyms: 2310045A20Rik, mKIAA0746) | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
Selenoh selenoprotein H (Synonyms: 2700094K13Rik, SelH) | |
Results | Reference |
1* | J:121143 Novoselov SV, Kryukov GV, Xu XM, Carlson BA, Hatfield DL, Gladyshev VN, Selenoprotein H is a nucleolar thioredoxin-like protein with a unique expression pattern. J Biol Chem. 2007 Apr 20;282(16):11960-8 |
Selenom selenoprotein M (Synonyms: 1500040L08Rik, Selm, SelM) | |
Results | Reference |
1* | J:174506 Lai HC, Klisch TJ, Roberts R, Zoghbi HY, Johnson JE, In vivo neuronal subtype-specific targets of Atoh1 (Math1) in dorsal spinal cord. J Neurosci. 2011 Jul 27;31(30):10859-71 |
Selenop selenoprotein P (Synonyms: D15Ucla1, selp, Se-P, Sepp1) | |
Results | Reference |
2* | J:140390 Lee SR, Yon JM, Baek IJ, Kim MR, Park CG, Lee BJ, Yun YW, Nam SY, Spatiotemporal expression of the selenoprotein P genein postimplantational mouse embryos. Int J Dev Biol. 2008;52(7):1005-11 |
1 | J:49017 Steinert P, Bachner D, Flohe L, Analysis of the mouse selenoprotein P gene. Biol Chem. 1998 Jun;379(6):683-91 |
Sema3a sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A (Synonyms: collapsin-1, Semad, sema III, semaphorin III, SemD) | |
Results | Reference |
1* | J:49945 Bagnard D, Lohrum M, Uziel D, Puschel AW, Bolz J, Semaphorins act as attractive and repulsive guidance signals during the development of cortical projections. Development. 1998 Dec;125(24):5043-53 |
1 | J:332313 Cantu-Guerra HL, Papazian MR, Gorsky AL, Alekos NS, Caccavano A, Karagulyan N, Neef J, Vicini S, Moser T, Coate TM, Cochlear hair cell innervation is dependent on a modulatory function of Semaphorin-3A. Dev Dyn. 2023 Jan;252(1):124-144 |
1 | J:126582 Cobos I, Borello U, Rubenstein JL, Dlx transcription factors promote migration through repression of axon and dendrite growth. Neuron. 2007 Jun 21;54(6):873-88 |
1 | J:226381 Homman-Ludiye J, Bourne JA, The guidance molecule Semaphorin3A is differentially involved in the arealization of the mouse and primate neocortex. Cereb Cortex. 2014 Nov;24(11):2884-98 |
2 | J:278733 Hossain MM, Tsuzuki T, Sakakibara K, Imaizumi F, Ikegaya A, Inagaki M, Takahashi I, Ito T, Takamatsu H, Kumanogoh A, Negishi T, Yukawa K, PlexinA1 is crucial for the midline crossing of callosal axons during corpus callosum development in BALB/cAJ mice. PLoS One. 2019;14(8):e0221440 |
1 | J:190719 Joza S, Wang J, Fox E, Hillman V, Ackerley C, Post M, Loss of semaphorin-neuropilin-1 signaling causes dysmorphic vascularization reminiscent of alveolar capillary dysplasia. Am J Pathol. 2012 Dec;181(6):2003-17 |
1* | J:95356 Kettunen P, Loes S, Furmanek T, Fjeld K, Kvinnsland IH, Behar O, Yagi T, Fujisawa H, Vainio S, Taniguchi M, Luukko K, Coordination of trigeminal axon navigation and patterning with tooth organ formation: epithelial-mesenchymal interactions, and epithelial Wnt4 and Tgf{beta}1 regulate semaphorin 3a expression in the dental mesenchyme. Development. 2005 Jan;132(2):323-334 |
1* | J:167053 Ko JA, Mizuno Y, Yanai R, Chikama T, Sonoda KH, Expression of semaphorin 3A and its receptors during mouse corneal development. Biochem Biophys Res Commun. 2010 Dec 17;403(3-4):305-9 |
1 | J:213341 Li W, Lin CY, Shang C, Han P, Xiong Y, Lin CJ, Yang J, Selleri L, Chang CP, Pbx1 activates Fgf10 in the mesenchyme of developing lungs. Genesis. 2014 May;52(5):399-407 |
1* | J:68163 Loes S, Kettunen P, Kvinnsland IH, Taniguchi M, Fujisawa H, Luukko K, Expression of class 3 semaphorins and neuropilin receptors in the developing mouse tooth. Mech Dev. 2001 Mar;101(1-2):191-4 |
1 | J:260018 Mata A, Gil V, Perez-Clausell J, Dasilva M, Gonzalez-Calixto MC, Soriano E, Garcia-Verdugo JM, Sanchez-Vives MV, Del Rio JA, New functions of Semaphorin 3E and its receptor PlexinD1 during developing and adult hippocampal formation. Sci Rep. 2018 Jan 22;8(1):1381 |
1 | J:187230 McKenna CC, Munjaal RP, Lwigale PY, Distinct roles for neuropilin1 and neuropilin2 during mouse corneal innervation. PLoS One. 2012;7(5):e37175 |
2 | J:214759 McKenna CC, Ojeda AF, Spurlin J 3rd, Kwiatkowski S, Lwigale PY, Sema3A maintains corneal avascularity during development by inhibiting Vegf induced angioblast migration. Dev Biol. 2014 Jul 15;391(2):241-50 |
1 | J:273473 McKey J, Bunce C, Batchvarov IS, Ornitz DM, Capel B, Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5570-5575 |
1* | J:183735 Moe K, Shrestha A, Kvinnsland IH, Luukko K, Kettunen P, Developmentally regulated expression of Sema3A chemorepellant in the developing mouse incisor. Acta Odontol Scand. 2012 May;70(3):184-9 |
1* | J:25500 Puschel AW, Adams RH, Betz H, Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension. Neuron. 1995 May;14(5):941-8 |
1 | J:206997 Ruediger T, Zimmer G, Barchmann S, Castellani V, Bagnard D, Bolz J, Integration of opposing semaphorin guidance cues in cortical axons. Cereb Cortex. 2013 Mar;23(3):604-14 |
1 | J:248731 Salehi P, Ge MX, Gundimeda U, Michelle Baum L, Lael Cantu H, Lavinsky J, Tao L, Myint A, Cruz C, Wang J, Nikolakopoulou AM, Abdala C, Kelley MW, Ohyama T, Coate TM, Friedman RA, Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea. PLoS Genet. 2017 Oct;13(10):e1007048 |
1* | J:41287 Zhou L, White FA, Lentz SI, Wright DE, Fisher DA, Snider WD, Cloning and expression of a novel murine semaphorin with structural similarity to insect semaphorin I. Mol Cell Neurosci. 1997 Jan;9(1):26-41 |
Sema3b sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B (Synonyms: LUCA-1, SemA, SemA, sema5, Semaa, semaV) | |
Results | Reference |
1 | J:226819 Coate TM, Spita NA, Zhang KD, Isgrig KT, Kelley MW, Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife. 2015;4 |
1* | J:68163 Loes S, Kettunen P, Kvinnsland IH, Taniguchi M, Fujisawa H, Luukko K, Expression of class 3 semaphorins and neuropilin receptors in the developing mouse tooth. Mech Dev. 2001 Mar;101(1-2):191-4 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1* | J:25500 Puschel AW, Adams RH, Betz H, Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension. Neuron. 1995 May;14(5):941-8 |
Sema3c sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C (Synonyms: 1110036B02Rik, Semae) | |
Results | Reference |
1* | J:49945 Bagnard D, Lohrum M, Uziel D, Puschel AW, Bolz J, Semaphorins act as attractive and repulsive guidance signals during the development of cortical projections. Development. 1998 Dec;125(24):5043-53 |
1 | J:226819 Coate TM, Spita NA, Zhang KD, Isgrig KT, Kelley MW, Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife. 2015;4 |
1 | J:226381 Homman-Ludiye J, Bourne JA, The guidance molecule Semaphorin3A is differentially involved in the arealization of the mouse and primate neocortex. Cereb Cortex. 2014 Nov;24(11):2884-98 |
2 | J:278733 Hossain MM, Tsuzuki T, Sakakibara K, Imaizumi F, Ikegaya A, Inagaki M, Takahashi I, Ito T, Takamatsu H, Kumanogoh A, Negishi T, Yukawa K, PlexinA1 is crucial for the midline crossing of callosal axons during corpus callosum development in BALB/cAJ mice. PLoS One. 2019;14(8):e0221440 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
2 | J:190719 Joza S, Wang J, Fox E, Hillman V, Ackerley C, Post M, Loss of semaphorin-neuropilin-1 signaling causes dysmorphic vascularization reminiscent of alveolar capillary dysplasia. Am J Pathol. 2012 Dec;181(6):2003-17 |
2 | J:349009 Kim N, Li Y, Yu R, Kwon HS, Song A, Jun MH, Jeong JY, Lee JH, Lim HH, Kim MJ, Kim JW, Oh WJ, Repulsive Sema3E-Plexin-D1 signaling coordinates both axonal extension and steering via activating an autoregulatory factor, Mtss1. Elife. 2024 Mar 25;13 |
1* | J:68163 Loes S, Kettunen P, Kvinnsland IH, Taniguchi M, Fujisawa H, Luukko K, Expression of class 3 semaphorins and neuropilin receptors in the developing mouse tooth. Mech Dev. 2001 Mar;101(1-2):191-4 |
1 | J:217046 Magnani D, Hasenpusch-Theil K, Benadiba C, Yu T, Basson MA, Price DJ, Lebrand C, Theil T, Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Cereb Cortex. 2014 Jan;24(1):186-98 |
1 | J:273473 McKey J, Bunce C, Batchvarov IS, Ornitz DM, Capel B, Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5570-5575 |
1 | J:310398 Mire E, Hocine M, Bazellieres E, Jungas T, Davy A, Chauvet S, Mann F, Developmental Upregulation of Ephrin-B1 Silences Sema3C/Neuropilin-1 Signaling during Post-crossing Navigation of Corpus Callosum Axons. Curr Biol. 2018 Jun 4;28(11):1768-1782.e4 |
1* | J:25500 Puschel AW, Adams RH, Betz H, Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension. Neuron. 1995 May;14(5):941-8 |
1 | J:206997 Ruediger T, Zimmer G, Barchmann S, Castellani V, Bagnard D, Bolz J, Integration of opposing semaphorin guidance cues in cortical axons. Cereb Cortex. 2013 Mar;23(3):604-14 |
2 | J:227426 Wiegreffe C, Simon R, Peschkes K, Kling C, Strehle M, Cheng J, Srivatsa S, Liu P, Jenkins NA, Copeland NG, Tarabykin V, Britsch S, Bcl11a (Ctip1) Controls Migration of Cortical Projection Neurons through Regulation of Sema3c. Neuron. 2015 Jul 15;87(2):311-25 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Sema3d sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D (Synonyms: 4631426B19Rik) | |
Results | Reference |
1 | J:226819 Coate TM, Spita NA, Zhang KD, Isgrig KT, Kelley MW, Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife. 2015;4 |
Sema3e sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E (Synonyms: mKIAA0331, Semah) | |
Results | Reference |
2 | J:46372 Christensen CR, Klingelhofer J, Tarabykina S, Hulgaard EF, Kramerov D, Lukanidin E, Transcription of a novel mouse semaphorin gene, M-semaH, correlates with the metastatic ability of mouse tumor cell lines. Cancer Res. 1998 Mar 15;58(6):1238-44 |
1 | J:260018 Mata A, Gil V, Perez-Clausell J, Dasilva M, Gonzalez-Calixto MC, Soriano E, Garcia-Verdugo JM, Sanchez-Vives MV, Del Rio JA, New functions of Semaphorin 3E and its receptor PlexinD1 during developing and adult hippocampal formation. Sci Rep. 2018 Jan 22;8(1):1381 |
2 | J:56478 Miyazaki N, Furuyama T, Sakai T, Fujioka S, Mori T, Ohoka Y, Takeda N, Kubo T, Inagaki S, Developmental localization of semaphorin H messenger RNA acting as a collapsing factor on sensory axons in the mouse brain. Neuroscience. 1999;93(1):401-8 |
1 | J:207212 Oh WJ, Gu C, Establishment of neurovascular congruency in the mouse whisker system by an independent patterning mechanism. Neuron. 2013 Oct 16;80(2):458-69 |
Sema3f sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F (Synonyms: Sema IV, Semak) | |
Results | Reference |
1 | J:226819 Coate TM, Spita NA, Zhang KD, Isgrig KT, Kelley MW, Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife. 2015;4 |
1* | J:52351 Eckhardt F, Meyerhans A, Cloning and expression pattern of a murine semaphorin homologous to H-sema IV. Neuroreport. 1998 Dec 1;9(17):3975-9 |
1 | J:190719 Joza S, Wang J, Fox E, Hillman V, Ackerley C, Post M, Loss of semaphorin-neuropilin-1 signaling causes dysmorphic vascularization reminiscent of alveolar capillary dysplasia. Am J Pathol. 2012 Dec;181(6):2003-17 |
1* | J:68163 Loes S, Kettunen P, Kvinnsland IH, Taniguchi M, Fujisawa H, Luukko K, Expression of class 3 semaphorins and neuropilin receptors in the developing mouse tooth. Mech Dev. 2001 Mar;101(1-2):191-4 |
1 | J:260018 Mata A, Gil V, Perez-Clausell J, Dasilva M, Gonzalez-Calixto MC, Soriano E, Garcia-Verdugo JM, Sanchez-Vives MV, Del Rio JA, New functions of Semaphorin 3E and its receptor PlexinD1 during developing and adult hippocampal formation. Sci Rep. 2018 Jan 22;8(1):1381 |
1 | J:187230 McKenna CC, Munjaal RP, Lwigale PY, Distinct roles for neuropilin1 and neuropilin2 during mouse corneal innervation. PLoS One. 2012;7(5):e37175 |
1 | J:273473 McKey J, Bunce C, Batchvarov IS, Ornitz DM, Capel B, Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5570-5575 |
1 | J:167943 Takeuchi H, Inokuchi K, Aoki M, Suto F, Tsuboi A, Matsuda I, Suzuki M, Aiba A, Serizawa S, Yoshihara Y, Fujisawa H, Sakano H, Sequential arrival and graded secretion of Sema3F by olfactory neuron axons specify map topography at the bulb. Cell. 2010 Jun 11;141(6):1056-67 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Sema3g sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G | |
Results | Reference |
1 | J:184199 Kutschera S, Weber H, Weick A, De Smet F, Genove G, Takemoto M, Prahst C, Riedel M, Mikelis C, Baulande S, Champseix C, Kummerer P, Conseiller E, Multon MC, Heroult M, Bicknell R, Carmeliet P, Betsholtz C, Augustin HG, Differential endothelial transcriptomics identifies semaphorin 3G as a vascular class 3 semaphorin. Arterioscler Thromb Vasc Biol. 2011 Jan;31(1):151-9 |
Sema4a sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A (Synonyms: Semab, SemB, SemB) | |
Results | Reference |
1 | J:273473 McKey J, Bunce C, Batchvarov IS, Ornitz DM, Capel B, Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5570-5575 |
1* | J:25500 Puschel AW, Adams RH, Betz H, Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension. Neuron. 1995 May;14(5):941-8 |
Sema4b sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B (Synonyms: Semac, SemC) | |
Results | Reference |
1* | J:25500 Puschel AW, Adams RH, Betz H, Murine semaphorin D/collapsin is a member of a diverse gene family and creates domains inhibitory for axonal extension. Neuron. 1995 May;14(5):941-8 |
Sema4c sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C (Synonyms: M-Sema F, Semacl1, Semacl1, Semaf, Semai) | |
Results | Reference |
1* | J:28378 Inagaki S, Furuyama T, Iwahashi Y, Identification of a member of mouse semaphorin family. FEBS Lett. 1995 Aug 21;370(3):269-72 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Sema4d sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D (Synonyms: CD100, coll-4, M-sema G, Semacl2, Semaj, semaphorin H, Semcl2) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Sema4f sema domain, immunoglobulin domain (Ig), TM domain, and short cytoplasmic domain (Synonyms: Sema W) | |
Results | Reference |
1* | J:189472 Armendariz BG, Bribian A, Perez-Martinez E, Martinez A, de Castro F, Soriano E, Burgaya F, Expression of Semaphorin 4F in neurons and brain oligodendrocytes and the regulation of oligodendrocyte precursor migration in the optic nerve. Mol Cell Neurosci. 2012 Jan;49(1):54-67 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Sema4g sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G | |
Results | Reference |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Sema5a sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A (Synonyms: 9130201M22Rik, M-Sema D, Semaf, semF) | |
Results | Reference |
1 | J:80875 Oster SF, Bodeker MO, He F, Sretavan DW, Invariant Sema5A inhibition serves an ensheathing function during optic nerve development. Development. 2003 Feb;130(4):775-84 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Sema5b sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5B (Synonyms: mKIAA1445, Semag, SemG, SemG) | |
Results | Reference |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Sema6a sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A (Synonyms: A730020P05Rik, sema, Sema6A-1, Semaq, VIa) | |
Results | Reference |
1* | J:79830 Garel S, Yun K, Grosschedl R, Rubenstein JL, The early topography of thalamocortical projections is shifted in Ebf1 and Dlx1/2 mutant mice. Development. 2002 Dec;129(24):5621-34 |
1 | J:226381 Homman-Ludiye J, Bourne JA, The guidance molecule Semaphorin3A is differentially involved in the arealization of the mouse and primate neocortex. Cereb Cortex. 2014 Nov;24(11):2884-98 |
1 | J:150482 Little GE, Lopez-Bendito G, Runker AE, Garcia N, Pinon MC, Chedotal A, Molnar Z, Mitchell KJ, Specificity and plasticity of thalamocortical connections in Sema6A mutant mice. PLoS Biol. 2009 Apr 28;7(4):e98 |
1 | J:273473 McKey J, Bunce C, Batchvarov IS, Ornitz DM, Capel B, Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5570-5575 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
1* | J:41287 Zhou L, White FA, Lentz SI, Wright DE, Fisher DA, Snider WD, Cloning and expression of a novel murine semaphorin with structural similarity to insect semaphorin I. Mol Cell Neurosci. 1997 Jan;9(1):26-41 |
Sema6b sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B (Synonyms: Sema, Seman, semaZ, VIb) | |
Results | Reference |
1 | J:160509 Tawarayama H, Yoshida Y, Suto F, Mitchell KJ, Fujisawa H, Roles of semaphorin-6B and plexin-A2 in lamina-restricted projection of hippocampal mossy fibers. J Neurosci. 2010 May 19;30(20):7049-60 |
Sema6c sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6C (Synonyms: mKIAA1869, Semay, Sema Y) | |
Results | Reference |
1 | J:273473 McKey J, Bunce C, Batchvarov IS, Ornitz DM, Capel B, Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5570-5575 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
Sema6d sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (Synonyms: 1110067B02Rik, mKIAA1479, Sema6D-1, Sema6D-2, Sema6D-4, Sema6D-5, Sema6D-6) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:87694 Taniguchi M, Shimizu T, Characterization of a novel member of murine semaphorin family. Biochem Biophys Res Commun. 2004 Jan 30;314(1):242-8 |
Sema7a sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A (Synonyms: 2900057C09Rik, CDw108, Semal, Semaphorin K1) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Senp2 SUMO/sentrin specific peptidase 2 (Synonyms: 2310007L05Rik, 4930538C18Rik, mKIAA1331) | |
Results | Reference |
1* | J:315590 Fujiwara K, Hasegawa K, Oka M, Yoneda Y, Yoshikawa K, Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system. Genes Cells. 2016 Nov;21(11):1176-1194 |
1 | J:183651 Kim EY, Chen L, Ma Y, Yu W, Chang J, Moskowitz IP, Wang J, Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J Mol Cell Cardiol. 2012 Mar;52(3):638-49 |
1 | J:294283 Liang Q, Zheng Q, Zuo Y, Chen Y, Ma J, Ni P, Cheng J, SENP2 Suppresses Necdin Expression to Promote Brown Adipocyte Differentiation. Cell Rep. 2019 Aug 20;28(8):2004-2011.e4 |
Senp3 SUMO/sentrin specific peptidase 3 (Synonyms: Smt3ip1) | |
Results | Reference |
1* | J:317437 Yamada S, Sato A, Ishihara N, Akiyama H, Sakakibara SI, Drp1 SUMO/deSUMOylation by Senp5 isoforms influences ER tubulation and mitochondrial dynamics to regulate brain development. iScience. 2021 Dec 17;24(12):103484 |
Senp5 SUMO/sentrin specific peptidase 5 (Synonyms: 6230429P13Rik, A730063F07Rik) | |
Results | Reference |
2* | J:317437 Yamada S, Sato A, Ishihara N, Akiyama H, Sakakibara SI, Drp1 SUMO/deSUMOylation by Senp5 isoforms influences ER tubulation and mitochondrial dynamics to regulate brain development. iScience. 2021 Dec 17;24(12):103484 |
Septin1 septin 1 (Synonyms: Diff6, PNUTL3, Sept1) | |
Results | Reference |
1* | J:320379 Ito H, Morishita R, Noda M, Iwamoto I, Nagata KI, Biochemical and morphological characterization of SEPT1 in mouse brain. Med Mol Morphol. 2020 Dec;53(4):221-228 |
Septin2 septin 2 (Synonyms: mKIAA0158, Nedd5, Sept2) | |
Results | Reference |
1 | J:41234 Kinoshita M, Kumar S, Mizoguchi A, Ide C, Kinoshita A, Haraguchi T , Hiraoka Y , Noda M, Nedd5, a mammalian septin, is a novel cytoskeletal component interacting with actin-based structures. Genes Dev. 1997 Jun 15;11(12):1535-47 |
Septin3 septin 3 (Synonyms: 3110018K01Rik, B530002E20Rik, Gm46500, Sep3, Sept3) | |
Results | Reference |
1* | J:57028 Xiong JW, Leahy A, Stuhlmann H, Retroviral promoter-trap insertion into a novel mammalian septin gene expressed during mouse neuronal development. Mech Dev. 1999 Aug;86(1-2):183-91 |
Septin11 septin 11 (Synonyms: 6230410I01Rik, D5Ertd606e, Sept11) | |
Results | Reference |
1* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
Serpina1 serine (or cysteine) peptidase inhibitor, clade A, member 1 cluster (Synonyms: [a]1-antitrypsin, [a]1-PI, [a]1-proteinase inhibitor, Aat, alpha-1 antiproteinase, antitrypsin, Pre, Pre-1, Spi-1, Spi1) | |
Results | Reference |
1* | J:120667 Bouzin C, Clotman F, Renauld JC, Lemaigre FP, Rousseau GG, The onecut transcription factor hepatocyte nuclear factor-6 controls B lymphopoiesis in fetal liver. J Immunol. 2003 Aug 1;171(3):1297-303 |
Serpina1e serine (or cysteine) peptidase inhibitor, clade A, member 1E (Synonyms: PI5, Spi1-5) | |
Results | Reference |
2 | J:307817 Theis A, Singer RA, Garofalo D, Paul A, Narayana A, Sussel L, Groucho co-repressor proteins regulate beta cell development and proliferation by repressing Foxa1 in the developing mouse pancreas. Development. 2021 Mar 24;148(6):dev192401 |
Serpina5 serine (or cysteine) peptidase inhibitor, clade A, member 5 (Synonyms: alpha-1 antiproteinase, antitrypsin, PAI-3, Pci) | |
Results | Reference |
2* | J:161870 Wagenaar GT, Uhrin P, Weipoltshammer K, Almeder M, Hiemstra PS, Geiger M, Meijers JC, Schofer C, Expression patterns of protein C inhibitor in mouse development. J Mol Histol. 2010 Feb;41(1):27-37 |
Serpina12 serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 12 (Synonyms: vaspin) | |
Results | Reference |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Serpinb5 serine (or cysteine) peptidase inhibitor, clade B, member 5 (Synonyms: 1110036M19Rik, Maspin, ovalbumin, Spi7) | |
Results | Reference |
1 | J:188148 Landin MA, Shabestari M, Babaie E, Reseland JE, Osmundsen H, Gene Expression Profiling during Murine Tooth Development. Front Genet. 2012;3:139 |
Serpinb6a serine (or cysteine) peptidase inhibitor, clade B, member 6a (Synonyms: 4930482L21Rik, D330015H01Rik, ovalbumin, Spi3) | |
Results | Reference |
1* | J:164931 Sirmaci A, Erbek S, Price J, Huang M, Duman D, Cengiz FB, Bademci G, Tokgoz-Yilmaz S, Hismi B, Ozdag H, Ozturk B, Kulaksizoglu S, Yildirim E, Kokotas H, Grigoriadou M, Petersen MB, Shahin H, Kanaan M, King MC, Chen ZY, Blanton SH, Liu XZ, Zuchner S, AkarN, Tekin M, A truncating mutation in SERPINB6 is associated with autosomal-recessive nonsyndromic sensorineural hearing loss. Am J Hum Genet. 2010 May 14;86(5):797-804 |
Serpine1 serine (or cysteine) peptidase inhibitor, clade E, member 1 (Synonyms: PAI-1, PAI1, Planh1) | |
Results | Reference |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1 | J:250062 Li A, Ma S, Smith SM, Lee MK, Fischer A, Borok Z, Bellusci S, Li C, Minoo P, Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate. BMC Biol. 2016 Mar 16;14:19 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
Serpine2 serine (or cysteine) peptidase inhibitor, clade E, member 2 (Synonyms: B230326M24Rik, nexin, PI7, PN-1, protease nexin 1, Spi4) | |
Results | Reference |
1 | J:139818 Feutz AC, Barrandon Y, Monard D, Control of thrombin signaling through PI3K is a mechanism underlying plasticity between hair follicle dermal sheath and papilla cells. J Cell Sci. 2008 May 1;121(Pt 9):1435-43 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1* | J:16551 Mansuy IM, van der Putten H, Schmid P, Meins M, Botteri FM, Monard D, Variable and multiple expression of Protease Nexin-1 during mouse organogenesis and nervous system development. Development. 1993 Dec;119(4):1119-34 |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
1* | J:239225 Scott KK, Norris RA, Potter SS, Norrington DW, Baybo MA, Hicklin DM, Kern MJ, GeneChip microarrays facilitate identification of Protease Nexin-1 as a target gene of the Prx2 (S8) homeoprotein. DNA Cell Biol. 2003 Feb;22(2):95-105 |
Serpinf1 serine (or cysteine) peptidase inhibitor, clade F, member 1 (Synonyms: EPC-1, Pedf, Pedfl, pigment epithelium derived factor, Sdf3) | |
Results | Reference |
1 | J:48124 Kozaki K, Miyaishi O, Koiwai O, Yasui Y, Kashiwai A, Nishikawa Y, Shimizu S, Saga S, Isolation, purification, and characterization of a collagen-associated serpin, caspin, produced by murine colon adenocarcinoma cells. J Biol Chem. 1998 Jun 12;273(24):15125-30 |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Serping1 serine (or cysteine) peptidase inhibitor, clade G, member 1 (Synonyms: C1INH, C1 inhibitor, C1nh) | |
Results | Reference |
1 | J:310898 Gorelik A, Sapir T, Woodruff TM, Reiner O, Serping1/C1 Inhibitor Affects Cortical Development in a Cell Autonomous and Non-cell Autonomous Manner. Front Cell Neurosci. 2017;11:169 |
Serpinh1 serine (or cysteine) peptidase inhibitor, clade H, member 1 (Synonyms: Cbp1, Cbp2, colligin, gp46, Hsp47, J6, Serpinh2) | |
Results | Reference |
1* | J:51222 Bachner D, Ahrens M, Schroder D, Hoffmann A, Lauber J, Betat N, Steinert P, Flohe L, Gross G, Bmp-2 downstream targets in mesenchymal development identified by subtractive cloning from recombinant mesenchymal progenitors (C3H10T1/2). Dev Dyn. 1998 Dec;213(4):398-411 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
1* | J:52896 Masuda H, Hosokawa N, Nagata K, Expression and localization of collagen-binding stress protein Hsp47 in mouse embryo development: comparison with types I and II collagen. Cell Stress Chaperones. 1998 Dec;3(4):256-64 |
4* | J:36919 Tanaka Y, Kobayashi K, Kita M, Masuda H, Kinoshita S, Nagata K, Imanishi J, Expression of 47 kDa heat shock protein (HSP47) during development of mouse cornea. Exp Eye Res. 1996 Oct;63(4):383-93 |
Setd2 SET domain containing 2 (Synonyms: 4921524K10Rik, KMT3A) | |
Results | Reference |
1 | J:346179 Abe S, Nagatomo H, Sasaki H, Ishiuchi T, A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation. Epigenetics. 2021 Oct;16(10):1123-1134 |
Setd5 SET domain containing 5 (Synonyms: 2900045N06Rik, mKIAA1757) | |
Results | Reference |
1 | J:271411 Deliu E, Arecco N, Morandell J, Dotter CP, Contreras X, Girardot C, Kasper EL, Kozlova A, Kishi K, Chiaradia I, Noh KM, Novarino G, Haploinsufficiency of the intellectual disability gene SETD5 disturbs developmental gene expression and cognition. Nat Neurosci. 2018 Dec;21(12):1717-1727 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Setd7 SET domain containing (lysine methyltransferase) 7 (Synonyms: 1600028F23Rik, KMT7, mKIAA1717, Set7, Set7/9) | |
Results | Reference |
1 | J:346895 Guo P, Lim RC, Rajawasam K, Trinh T, Sun H, Zhang H, A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis. Elife. 2024 Feb 12;13 |
Setdb1 SET domain, bifurcated 1 (Synonyms: ESET, KMT1E, mKIAA0067) | |
Results | Reference |
1 | J:173973 Benlhabib H, Mendelson CR, Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia. Mol Cell Biol. 2011 May;31(10):1949-58 |
2* | J:194983 Ideno H, Shimada A, Imaizumi K, Kimura H, Abe M, Nakashima K, Nifuji A, Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development. Gene Expr Patterns. 2013 Mar-Apr;13(3-4):84-90 |
Sez6 seizure related gene 6 (Synonyms: D11Bhm177e, sez-6) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Sez6l seizure related 6 homolog like (Synonyms: Acig1, mKIAA0927) | |
Results | Reference |
1 | J:267715 Wiwatpanit T, Lorenzen SM, Cantu JA, Foo CZ, Hogan AK, Marquez F, Clancy JC, Schipma MJ, Cheatham MA, Duggan A, Garcia-Anoveros J, Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1. Nature. 2018 Nov;563(7733):691-695 |
Sf1 splicing factor 1 (Synonyms: CW17R, MZFM, WBP4, Zfp162) | |
Results | Reference |
1 | J:230219 Ishizuka A, Hasegawa Y, Ishida K, Yanaka K, Nakagawa S, Formation of nuclear bodies by the lncRNA Gomafu-associating proteins Celf3 and SF1. Genes Cells. 2014 Sep;19(9):704-21 |
Sfmbt2 Scm-like with four mbt domains 2 (Synonyms: D2Wsu23e, D330030P06Rik) | |
Results | Reference |
1* | J:83414 Tanaka TS, Kunath T, Kimber WL, Jaradat SA, Stagg CA, Usuda M, Yokota T, Niwa H, Rossant J, Ko MS, Gene expression profiling of embryo-derived stem cells reveals candidate genes associated with pluripotency and lineage specificity. Genome Res. 2002 Dec;12(12):1921-8 |
Sfn stratifin (Synonyms: 14-3-3, 14-3-3 sigma, Er, MME1, Ywhas) | |
Results | Reference |
1 | J:158529 Burgess D, Zhang Y, Siefker E, Vaca R, Kuracha MR, Reneker L, Overbeek PA, Govindarajan V, Activated Ras alters lens and corneal development through induction of distinct downstream targets. BMC Dev Biol. 2010;10:13 |
1 | J:133461 Choi PS, Zakhary L, Choi WY, Caron S, Alvarez-Saavedra E, Miska EA, McManus M, Harfe B, Giraldez AJ, Horvitz RH, Schier AF, Dulac C, Members of the miRNA-200 family regulate olfactory neurogenesis. Neuron. 2008 Jan 10;57(1):41-55 |
1 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
Sfpq splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated) (Synonyms: 1110004P21Rik, 2810416M14Rik, 5730453G22Rik, 9030402K04Rik, D4Ertd314e, PSF, REP1) | |
Results | Reference |
1 | J:271630 Takeuchi A, Iida K, Tsubota T, Hosokawa M, Denawa M, Brown JB, Ninomiya K, Ito M, Kimura H, Abe T, Kiyonari H, Ohno K, Hagiwara M, Loss of Sfpq Causes Long-Gene Transcriptopathy in the Brain. Cell Rep. 2018 May 1;23(5):1326-1341 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Sfrp1 secreted frizzled-related protein 1 (Synonyms: 2210415K03Rik, sFRP-1) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
2 | J:163382 Foronjy R, Imai K, Shiomi T, Mercer B, Sklepkiewicz P, Thankachen J, Bodine P, D'Armiento J, The divergent roles of secreted frizzled related protein-1 (SFRP1) in lung morphogenesis and emphysema. Am J Pathol. 2010 Aug;177(2):598-607 |
1 | J:171428 Li J, Huang X, Xu X, Mayo J, Bringas P Jr, Jiang R, Wang S, Chai Y, SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis. Development. 2011 May;138(10):1977-89 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:321068 Maimets M, Pedersen MT, Guiu J, Dreier J, Thodberg M, Antoku Y, Schweiger PJ, Rib L, Bressan RB, Miao Y, Garcia KC, Sandelin A, Serup P, Jensen KB, Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling. Nat Commun. 2022 Feb 7;13(1):715 |
1 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
1 | J:123406 Miquelajauregui A, Van de Putte T, Polyakov A, Nityanandam A, Boppana S, Seuntjens E, Karabinos A, Higashi Y, Huylebroeck D, Tarabykin V, Smad-interacting protein-1 (Zfhx1b) acts upstream of Wnt signaling in the mouse hippocampus and controls its formation. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12919-24 |
1 | J:261627 Mori K, Nakamura H, Kurooka H, Miyachi H, Tamada K, Sugai M, Takumi T, Yokota Y, Id2 determines intestinal identity through repression of the foregut transcription factor, Irx5. Mol Cell Biol. 2018 Feb 20; |
1 | J:146606 Pritchard C, Mecham B, Dumpit R, Coleman I, Bhattacharjee M, Chen Q, Sikes RA, Nelson PS, Conserved gene expression programs integrate mammalian prostate development and tumorigenesis. Cancer Res. 2009 Mar 1;69(5):1739-47 |
1* | J:137794 Trevant B, Gaur T, Hussain S, Symons J, Komm BS, Bodine PV, Stein GS, Lian JB, Expression of secreted frizzled related protein 1, a Wnt antagonist, in brain, kidney, and skeleton is dispensable for normal embryonic development. J Cell Physiol. 2008 Oct;217(1):113-26 |
1 | J:147206 Warr N, Siggers P, Bogani D, Brixey R, Pastorelli L, Yates L, Dean CH, Wells S, Satoh W, Shimono A, Greenfield A, Sfrp1 and Sfrp2 are required for normal male sexual development in mice. Dev Biol. 2009 Feb 15;326(2):273-84 |
Sfrp2 secreted frizzled-related protein 2 (Synonyms: Sdf5) | |
Results | Reference |
1 | J:353312 Adutwum-Ofosu K, Magnani D, Theil T, Price DJ, Fotaki, The molecular and cellular signatures of the mouse eminentia thalami support its role as a signalling centre in the developing forebrain. Brain Struct Funct. 2016;221(7):3709-27 |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1* | J:70346 Kim AS, Anderson SA, Rubenstein JL, Lowenstein DH, Pleasure SJ, Pax-6 regulates expression of SFRP-2 and Wnt-7b in the developing CNS. J Neurosci. 2001 Mar 1;21(5):RC132 |
1* | J:49904 Leimeister C, Bach A, Gessler M, Developmental expression patterns of mouse sFRP genes encoding members of the secreted frizzled related protein family. Mech Dev. 1998 Jul;75(1-2):29-42 |
1* | J:51287 Lescher B, Haenig B, Kispert A, sFRP-2 is a target of the Wnt-4 signaling pathway in the developing metanephric kidney. Dev Dyn. 1998 Dec;213(4):440-51 |
1 | J:171428 Li J, Huang X, Xu X, Mayo J, Bringas P Jr, Jiang R, Wang S, Chai Y, SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis. Development. 2011 May;138(10):1977-89 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:220152 Marcos S, Nieto-Lopez F, Sandonis A, Cardozo MJ, Di Marco F, Esteve P, Bovolenta P, Secreted frizzled related proteins modulate pathfinding and fasciculation of mouse retina ganglion cell axons by direct and indirect mechanisms. J Neurosci. 2015 Mar 18;35(11):4729-40 |
1 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
2 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
1 | J:261627 Mori K, Nakamura H, Kurooka H, Miyachi H, Tamada K, Sugai M, Takumi T, Yokota Y, Id2 determines intestinal identity through repression of the foregut transcription factor, Irx5. Mol Cell Biol. 2018 Feb 20; |
1 | J:328944 Olbertova K, Hrckulak D, Kriz V, Jesionek W, Kubovciak J, Esner M, Korinek V, Buchtova M, Role of LGR5-positive mesenchymal cells in craniofacial development. Front Cell Dev Biol. 2022;10:810527 |
1 | J:146606 Pritchard C, Mecham B, Dumpit R, Coleman I, Bhattacharjee M, Chen Q, Sikes RA, Nelson PS, Conserved gene expression programs integrate mammalian prostate development and tumorigenesis. Cancer Res. 2009 Mar 1;69(5):1739-47 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
2 | J:341689 Zhang B, Zhao C, Shen W, Li W, Zheng Y, Kong X, Wang J, Wu X, Zeng T, Liu Y, Zhou Y, KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors. Nat Commun. 2023 Oct 14;14(1):6489 |
3* | J:105879 Zhang TJ, Hoffman BG, Ruiz de Algara T, Helgason CD, SAGE reveals expression of Wnt signalling pathway members during mouse prostate development. Gene Expr Patterns. 2006 Mar;6(3):310-24 |
Sfrp4 secreted frizzled-related protein 4 | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
2 | J:315409 Huyghe A, Van den Ackerveken P, Sacheli R, Prevot PP, Thelen N, Renauld J, Thiry M, Delacroix L, Nguyen L, Malgrange B, MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5. Cell Rep. 2015 Oct 6;13(1):31-42 |
Sfrp5 secreted frizzled-related sequence protein 5 (Synonyms: SARP3) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
2 | J:315409 Huyghe A, Van den Ackerveken P, Sacheli R, Prevot PP, Thelen N, Renauld J, Thiry M, Delacroix L, Nguyen L, Malgrange B, MicroRNA-124 Regulates Cell Specification in the Cochlea through Modulation of Sfrp4/5. Cell Rep. 2015 Oct 6;13(1):31-42 |
1* | J:154372 Li X, Udager AM, Hu C, Qiao XT, Richards N, Gumucio DL, Dynamic patterning at the pylorus: Formation of an epithelial intestine-stomach boundary in late fetal life. Dev Dyn. 2009 Oct 29;238(12):3205-3217 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Sfta3 surfactant associated 3 (Synonyms: E030019B13Rik, Nanci, Sfta3-ps) | |
Results | Reference |
1* | J:212084 Herriges MJ, Swarr DT, Morley MP, Rathi KS, Peng T, Stewart KM, Morrisey EE, Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development. Genes Dev. 2014 Jun 15;28(12):1363-79 |
1* | J:243650 Herriges MJ, Tischfield DJ, Cui Z, Morley MP, Han Y, Babu A, Li S, Lu M, Cendan I, Garcia BA, Anderson SA, Morrisey EE, The NANCI-Nkx2.1 gene duplex buffers Nkx2.1 expression to maintain lung development and homeostasis. Genes Dev. 2017 May 01;31(9):889-903 |
Sftpa1 surfactant associated protein A1 (Synonyms: Sftp-1, Sftp1, SFTPA1, SP-A, surfactant pulmonary associated protein A1) | |
Results | Reference |
1 | J:173973 Benlhabib H, Mendelson CR, Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia. Mol Cell Biol. 2011 May;31(10):1949-58 |
1 | J:104973 Besnard V, Wert SE, Kaestner KH, Whitsett JA, Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1. Am J Physiol Lung Cell Mol Physiol. 2005 Nov;289(5):L750-9 |
1 | J:173840 El-Hashash AH, Al Alam D, Turcatel G, Rogers O, Li X, Bellusci S, Warburton D, Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. Dev Biol. 2011 May 15;353(2):242-58 |
1 | J:150516 Hu Z, Wang C, Xiao Y, Sheng N, Chen Y, Xu Y, Zhang L, Mo W, Jing N, Hu G, NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development. J Cell Sci. 2009 Apr 15;122(Pt 8):1145-54 |
1* | J:33469 Jaskoll T, Choy HA, Melnick M, The glucocorticoid-glucocorticoid receptor signal transduction pathway, transforming growth factor-beta, and embryonic mouse lung development in vivo. Pediatr Res. 1996 May;39(5):749-59 |
2 | J:213341 Li W, Lin CY, Shang C, Han P, Xiong Y, Lin CJ, Yang J, Selleri L, Chang CP, Pbx1 activates Fgf10 in the mesenchyme of developing lungs. Genesis. 2014 May;52(5):399-407 |
1 | J:267889 Moon S, Im SK, Kim N, Youn H, Park UH, Kim JY, Kim AR, An SJ, Kim JH, Sun W, Hwang JT, Kim EJ, Um SJ, Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis. Cell Death Dis. 2018 Nov 2;9(11):1118 |
1 | J:53721 Muglia LJ, Bae DS, Brown TT, Vogt SK, Alvarez JG, Sunday ME, Majzoub JA, Proliferation and differentiation defects during lung development in corticotropin-releasing hormone-deficient mice. Am J Respir Cell Mol Biol. 1999 Feb;20(2):181-8 |
1 | J:97215 Okubo T, Knoepfler PS, Eisenman RN, Hogan BL, Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation. Development. 2005 Mar;132(6):1363-74 |
1 | J:135431 Salminen A, Paananen R, Vuolteenaho R, Metsola J, Ojaniemi M, Autio-Harmainen H, Hallman M, Maternal endotoxin-induced preterm birth in mice: fetal responses in toll-like receptors, collectins, and cytokines. Pediatr Res. 2008 Mar;63(3):280-6 |
1* | J:73304 Tebar M, Destree O, de Vree WJ, Ten Have-Opbroek AA, Expression of Tcf/Lef and sFrp and localization of beta-catenin in the developing mouse lung. Mech Dev. 2001 Dec;109(2):437-40 |
1 | J:44870 Ten Have-Opbroek AA, Lung development in the mouse embryo. Exp Lung Res. 1991 Mar-Apr;17(2):111-30 |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
Sftpb surfactant associated protein B (Synonyms: SF-B, Sftp-3, Sftp3, SP-B) | |
Results | Reference |
1 | J:180979 Besnard V, Wert SE, Ikegami M, Xu Y, Heffner C, Murray SA, Donahue LR, Whitsett JA, Maternal synchronization of gestational length and lung maturation. PLoS One. 2011;6(11):e26682 |
2* | J:104973 Besnard V, Wert SE, Kaestner KH, Whitsett JA, Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1. Am J Physiol Lung Cell Mol Physiol. 2005 Nov;289(5):L750-9 |
1 | J:202949 Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J, Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18042-51 |
1* | J:84360 Dalvin S, Anselmo MA, Prodhan P, Komatsuzaki K, Schnitzer JJ, Kinane TB, Expression of Netrin-1 and its two receptors DCC and UNC5H2 in the developing mouse lung. Gene Expr Patterns. 2003 Jun;3(3):279-83 |
1 | J:94928 De Paepe ME, Mao Q, Embree-Ku M, Rubin LP, Luks FI, Fas/FasL-mediated apoptosis in perinatal murine lungs. Am J Physiol Lung Cell Mol Physiol. 2004 Oct;287(4):L730-42 |
1* | J:149067 Grier DG, Thompson A, Lappin TR, Halliday HL, Quantification of Hox and Surfactant Protein-B Transcription during Murine Lung Development. Neonatology. 2009 Feb 10;96(1):50-60 |
1 | J:233686 Jia WJ, Jiang S, Tang QL, Shen D, Xue B, Ning W, Li CJ, Geranylgeranyl Diphosphate Synthase Modulates Fetal Lung Branching Morphogenesis Possibly through Controlling K-Ras Prenylation. Am J Pathol. 2016 Jun;186(6):1454-65 |
2 | J:213341 Li W, Lin CY, Shang C, Han P, Xiong Y, Lin CJ, Yang J, Selleri L, Chang CP, Pbx1 activates Fgf10 in the mesenchyme of developing lungs. Genesis. 2014 May;52(5):399-407 |
1 | J:267889 Moon S, Im SK, Kim N, Youn H, Park UH, Kim JY, Kim AR, An SJ, Kim JH, Sun W, Hwang JT, Kim EJ, Um SJ, Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis. Cell Death Dis. 2018 Nov 2;9(11):1118 |
1 | J:53721 Muglia LJ, Bae DS, Brown TT, Vogt SK, Alvarez JG, Sunday ME, Majzoub JA, Proliferation and differentiation defects during lung development in corticotropin-releasing hormone-deficient mice. Am J Respir Cell Mol Biol. 1999 Feb;20(2):181-8 |
1 | J:121421 Shu W, Lu MM, Zhang Y, Tucker PW, Zhou D, Morrisey EE, Foxp2 and Foxp1 cooperatively regulate lung and esophagus development. Development. 2007 May;134(10):1991-2000 |
1* | J:61159 Stahlman MT, Gray MP, Falconieri MW, Whitsett JA, Weaver TE, Lamellar body formation in normal and surfactant protein B-deficient fetal mice. Lab Invest. 2000 Mar;80(3):395-403 |
1* | J:97487 Xu J, Tian J, Shapiro SD, Normal Lung Development in RAIG1-Deficient Mice Despite Unique Lung Epithelium-Specific Expression. Am J Respir Cell Mol Biol. 2005 May;32(5):381-7 |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
Sftpc surfactant associated protein C (Synonyms: Bricd6, pro-SpC, Sftp-2, Sftp2, SP-C, SPC) | |
Results | Reference |
1* | J:33591 Bellusci S, Henderson R, Winnier G, Oikawa T, Hogan BL, Evidence from normal expression and targeted misexpression that bone morphogenetic protein (Bmp-4) plays a role in mouse embryonic lung morphogenesis. Development. 1996 Jun;122(6):1693-702 |
1 | J:180979 Besnard V, Wert SE, Ikegami M, Xu Y, Heffner C, Murray SA, Donahue LR, Whitsett JA, Maternal synchronization of gestational length and lung maturation. PLoS One. 2011;6(11):e26682 |
2* | J:104973 Besnard V, Wert SE, Kaestner KH, Whitsett JA, Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1. Am J Physiol Lung Cell Mol Physiol. 2005 Nov;289(5):L750-9 |
1 | J:316183 Cai Y, Yoneda M, Tomita T, Kurotani R, Okamoto M, Kido T, Abe H, Mitzner W, Guha A, Kimura S, Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice. BMC Pulm Med. 2015 Jul 16;15:72 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1* | J:291486 Daniel E, Barlow HR, Sutton GI, Gu X, Htike Y, Cowdin MA, Cleaver O, Cyp26b1 is an essential regulator of distal airway epithelial differentiation during lung development. Development. 2020 Feb 20;147(4):dev181560 |
1 | J:173840 El-Hashash AH, Al Alam D, Turcatel G, Rogers O, Li X, Bellusci S, Warburton D, Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. Dev Biol. 2011 May 15;353(2):242-58 |
2 | J:28082 Holmberg M, Leonardsson G, Ny T, The species-specific differences in the cAMP regulation of the tissue-type plasminogen activator gene between rat, mouse and human is caused by a one-nucleotide substitution in the cAMP-responsive element of the promoters. Eur J Biochem. 1995 Jul 15;231(2):466-74 |
1 | J:150516 Hu Z, Wang C, Xiao Y, Sheng N, Chen Y, Xu Y, Zhang L, Mo W, Jing N, Hu G, NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development. J Cell Sci. 2009 Apr 15;122(Pt 8):1145-54 |
1 | J:81588 Kaplan F, Comber J, Sladek R, Hudson TJ, Muglia LJ, Macrae T, Gagnon S, Asada M, Brewer JA, Sweezey NB, The growth factor midkine is modulated by both glucocorticoid and retinoid in fetal lung development. Am J Respir Cell Mol Biol. 2003 Jan;28(1):33-41 |
1 | J:178426 Kishimoto K, Nishizuka M, Ueda T, Kajita K, Ugawa S, Shimada S, Osada S, Imagawa M, Indispensable role of factor for adipocyte differentiation 104 (fad104) in lung maturation. Exp Cell Res. 2011 Sep 10;317(15):2110-23 |
1 | J:237343 Laresgoiti U, Nikolic MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL, Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016 Oct 15;143(20):3686-3699 |
2 | J:213341 Li W, Lin CY, Shang C, Han P, Xiong Y, Lin CJ, Yang J, Selleri L, Chang CP, Pbx1 activates Fgf10 in the mesenchyme of developing lungs. Genesis. 2014 May;52(5):399-407 |
1 | J:315454 Loscertales M, Nicolaou F, Jeanne M, Longoni M, Gould DB, Sun Y, Maalouf FI, Nagy N, Donahoe PK, Type IV collagen drives alveolar epithelial-endothelial association and the morphogenetic movements of septation. BMC Biol. 2016 Jul 13;14:59 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1* | J:69279 Mailleux AA, Tefft D, Ndiaye D, Itoh N, Thiery JP, Warburton D, Bellusci S, Evidence that SPROUTY2 functions as an inhibitor of mouse embryonic lung growth and morphogenesis. Mech Dev. 2001 Apr;102(1-2):81-94 |
1 | J:316972 Mehta A, Dobersch S, Dammann RH, Bellusci S, Ilinskaya ON, Braun T, Barreto G, Validation of Tuba1a as appropriate internal control for normalization of gene expression analysis during mouse lung development. Int J Mol Sci. 2015 Feb 25;16(3):4492-511 |
1 | J:139210 Metzger DE, Stahlman MT, Shannon JM, Misexpression of ELF5 disrupts lung branching and inhibits epithelial differentiation. Dev Biol. 2008 Aug 1;320(1):149-60 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
1 | J:264719 Moghieb A, Clair G, Mitchell HD, Kitzmiller J, Zink EM, Kim YM, Petyuk V, Shukla A, Moore RJ, Metz TO, Carson J, McDermott JE, Corley RA, Whitsett JA, Ansong C, Time-resolved proteome profiling of normal lung development. Am J Physiol Lung Cell Mol Physiol. 2018 Jul 1;315(1):L11-L24 |
1 | J:267889 Moon S, Im SK, Kim N, Youn H, Park UH, Kim JY, Kim AR, An SJ, Kim JH, Sun W, Hwang JT, Kim EJ, Um SJ, Asxl1 exerts an antiproliferative effect on mouse lung maturation via epigenetic repression of the E2f1-Nmyc axis. Cell Death Dis. 2018 Nov 2;9(11):1118 |
1 | J:156690 Morimoto M, Liu Z, Cheng HT, Winters N, Bader D, Kopan R, Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate. J Cell Sci. 2010 Jan 15;123(Pt 2):213-24 |
1 | J:53721 Muglia LJ, Bae DS, Brown TT, Vogt SK, Alvarez JG, Sunday ME, Majzoub JA, Proliferation and differentiation defects during lung development in corticotropin-releasing hormone-deficient mice. Am J Respir Cell Mol Biol. 1999 Feb;20(2):181-8 |
1 | J:135340 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 maintains distal lung bud epithelium and excessive signaling leads to progenitor state arrest, distalization, and goblet cell metaplasia. BMC Dev Biol. 2008;8:2 |
1 | J:95881 Oblander SA, Zhou Z, Galvez BG, Starcher B, Shannon JM, Durbeej M, Arroyo AG, Tryggvason K, Apte SS, Distinctive functions of membrane type 1 matrix-metalloprotease (MT1-MMP or MMP-14) in lung and submandibular gland development are independent of its role in pro-MMP-2 activation. Dev Biol. 2005 Jan 1;277(1):255-69 |
1 | J:348633 Paramore SV, Trenado-Yuste C, Sharan R, Nelson CM, Devenport D, Vangl-dependent mesenchymal thinning shapes the distal lung during murine sacculation. Dev Cell. 2024 May 20;59(10):1302-1316.e5 |
1 | J:161760 Provost PR, Simard M, Tremblay Y, A link between lung androgen metabolism and the emergence of mature epithelial type II cells. Am J Respir Crit Care Med. 2004 Aug 1;170(3):296-305 |
1 | J:185114 Reynolds SD, Zemke AC, Giangreco A, Brockway BL, Teisanu RM, Drake JA, Mariani T, Di PY, Taketo MM, Stripp BR, Conditional stabilization of beta-catenin expands the pool of lung stem cells. Stem Cells. 2008 May;26(5):1337-46 |
2* | J:280280 Rutledge EA, Parvez RK, Short KM, Smyth IM, McMahon AP, Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease. Dev Biol. 2019 Oct 15;454(2):156-169 |
1 | J:191793 Schnatwinkel C, Niswander L, Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice. PLoS One. 2012;7(9):e44871 |
1 | J:338969 Shi CY, Elcavage LE, Chivukula RR, Stefano J, Kleaveland B, Bartel DP, ZSWIM8 destabilizes many murine microRNAs and is required for proper embryonic growth and development. Genome Res. 2023 Aug 2; |
1 | J:290284 Shrestha A, Carraro G, Nottet N, Vazquez-Armendariz AI, Herold S, Cordero J, Singh I, Wilhelm J, Barreto G, Morty R, El Agha E, Mari B, Chen C, Zhang JS, Chao CM, Bellusci S, A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development. Cell Mol Life Sci. 2019 Jul;76(14):2817-2832 |
1 | J:99391 Shu W, Guttentag S, Wang Z, Andl T, Ballard P, Lu MM, Piccolo S, Birchmeier W, Whitsett JA, Millar SE, Morrisey EE, Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung. Dev Biol. 2005 Jul 1;283(1):226-39 |
1 | J:121421 Shu W, Lu MM, Zhang Y, Tucker PW, Zhou D, Morrisey EE, Foxp2 and Foxp1 cooperatively regulate lung and esophagus development. Development. 2007 May;134(10):1991-2000 |
1* | J:61159 Stahlman MT, Gray MP, Falconieri MW, Whitsett JA, Weaver TE, Lamellar body formation in normal and surfactant protein B-deficient fetal mice. Lab Invest. 2000 Mar;80(3):395-403 |
1* | J:106945 Tremblay Y, Provost PR, 17beta-HSD type 5 expression and the emergence of differentiated epithelial Type II cells in fetal lung: A novel role for androgen during the surge of surfactant. Mol Cell Endocrinol. 2006 Mar 27;248(1-2):118-25 |
1 | J:99501 Wang J, Ito T, Udaka N, Okudela K, Yazawa T, Kitamura H, PI3K-AKT pathway mediates growth and survival signals during development of fetal mouse lung. Tissue Cell. 2005 Feb;37(1):25-35 |
1 | J:317033 Xie C, Abrams SR, Herranz-Perez V, Garcia-Verdugo JM, Reiter JF, Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity. Dev Cell. 2021 Dec 20;56(24):3334-3348.e6 |
1* | J:97487 Xu J, Tian J, Shapiro SD, Normal Lung Development in RAIG1-Deficient Mice Despite Unique Lung Epithelium-Specific Expression. Am J Respir Cell Mol Biol. 2005 May;32(5):381-7 |
1 | J:353791 Xu L, Tan C, Barr J, Talaba N, Verheyden J, Chin JS, Gaboyan S, Kasaraneni N, Elgamal RM, Gaulton KJ, Lin G, Afshar K, Golts E, Meier A, Alexander LEC, Borok Z, Shen Y, Chung WK, McCulley DJ, Sun X, Context-dependent roles of mitochondrial LONP1 in orchestrating the balance between airway progenitor versus progeny cells. Cell Stem Cell. 2024 Aug 16; |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
1* | J:68672 Zhao J, Chen H, Peschon JJ, Shi W, Zhang Y, Frank SJ, Warburton D, Pulmonary hypoplasia in mice lacking tumor necrosis factor-alpha converting enzyme indicates an indispensable role for cell surface protein shedding during embryonic lung branching morphogenesis. Dev Biol. 2001 Apr 1;232(1):204-18 |
Sftpd surfactant associated protein D (Synonyms: Sfpd, Sftp4, SP-D) | |
Results | Reference |
1 | J:104973 Besnard V, Wert SE, Kaestner KH, Whitsett JA, Stage-specific regulation of respiratory epithelial cell differentiation by Foxa1. Am J Physiol Lung Cell Mol Physiol. 2005 Nov;289(5):L750-9 |
1 | J:237343 Laresgoiti U, Nikolic MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL, Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016 Oct 15;143(20):3686-3699 |
2 | J:213341 Li W, Lin CY, Shang C, Han P, Xiong Y, Lin CJ, Yang J, Selleri L, Chang CP, Pbx1 activates Fgf10 in the mesenchyme of developing lungs. Genesis. 2014 May;52(5):399-407 |
1 | J:135431 Salminen A, Paananen R, Vuolteenaho R, Metsola J, Ojaniemi M, Autio-Harmainen H, Hallman M, Maternal endotoxin-induced preterm birth in mice: fetal responses in toll-like receptors, collectins, and cytokines. Pediatr Res. 2008 Mar;63(3):280-6 |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
Sgip1 SH3-domain GRB2-like (endophilin) interacting protein 1 (Synonyms: 3110007P09Rik) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Sgk1 serum/glucocorticoid regulated kinase 1 (Synonyms: Sgk) | |
Results | Reference |
1 | J:327415 Jing J, Feng J, Yuan Y, Guo T, Lei J, Pei F, Ho TV, Chai Y, Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022 Aug 16;13(1):4803 |
1* | J:69788 Lee E, Lein ES, Firestone GL, Tissue-specific expression of the transcriptionally regulated serum and glucocorticoid-inducible protein kinase (Sgk) during mouse embryogenesis. Mech Dev. 2001 May;103(1-2):177-81 |
Sgms1 sphingomyelin synthase 1 (Synonyms: 9530058O11Rik, SMS1, SMS1alpha1, SMS1alpha2, SMS1beta, SMS1gamma, Tmem23) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Sgms2 sphingomyelin synthase 2 (Synonyms: 4933405A16Rik, 5133401H06Rik) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Sgo2a shugoshin 2A (Synonyms: 1110007N04Rik, 5730576N04Rik, D1Ertd8e, Sgol2, Sgol2a, Tripin) | |
Results | Reference |
1 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
Sh2d3c SH2 domain containing 3C (Synonyms: Cas/HEF1-associated signal transducer, Chat, Nsp3, SH2-containing Eph receptor-binding protein 1, Shep1) | |
Results | Reference |
1 | J:164874 Wang L, Vervoort V, Wallez Y, Core N, Cremer H, Pasquale EB, The SRC homology 2 domain protein Shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain. J Neurosci. 2010 Sep 29;30(39):13201-10 |
Sh3glb1 SH3-domain GRB2-like B1 (endophilin) (Synonyms: Bif-1, Endophilin B1) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Sh3pxd2b SH3 and PX domains 2B (Synonyms: Fad49, G431001E03Rik, Tks4) | |
Results | Reference |
1* | J:158635 Iqbal Z, Cejudo-Martin P, de Brouwer A, van der Zwaag B, Ruiz-Lozano P, Scimia MC, Lindsey JD, Weinreb R, Albrecht B, Megarbane A, Alanay Y, Ben-Neriah Z, Amenduni M, Artuso R, Veltman JA, van Beusekom E, Oudakker A, Millan JL, Hennekam R, Hamel B, Courtneidge SA, van Bokhoven H, Disruption of the podosome adaptor protein TKS4 (SH3PXD2B) causes the skeletal dysplasia, eye, and cardiac abnormalities of Frank-Ter Haar Syndrome. Am J Hum Genet. 2010 Feb 12;86(2):254-61 |
Sh3rf1 SH3 domain containing ring finger 1 (Synonyms: 2200003J05Rik, Posh, Sh3md2) | |
Results | Reference |
1 | J:261829 Yang T, Sun Y, Zhang F, Zhu Y, Shi L, Li H, Xu Z, POSH localizes activated Rac1 to control the formation of cytoplasmic dilation of the leading process and neuronal migration. Cell Rep. 2012 Sep 27;2(3):640-51 |
Shank3 SH3 and multiple ankyrin repeat domains 3 (Synonyms: ProSAP2) | |
Results | Reference |
1 | J:94527 Schuetz G, Rosario M, Grimm J, Boeckers TM, Gundelfinger ED, Birchmeier W, The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells. J Cell Biol. 2004 Dec 6;167(5):945-52 |
Shbg sex hormone binding globulin | |
Results | Reference |
1 | J:246806 Li Y, Zhang L, Hu Y, Chen M, Han F, Qin Y, Chen M, Cui X, Duo S, Tang F, Gao F, beta-Catenin directs the transformation of testis Sertoli cells to ovarian granulosa-like cells by inducing Foxl2 expression. J Biol Chem. 2017 Oct 27;292(43):17577-17586 |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
Shc1 src homology 2 domain-containing transforming protein C1 (Synonyms: p66, p66shc, ShcA) | |
Results | Reference |
1* | J:166965 Hawley SP, Wills MK, Rabalski AJ, Bendall AJ, Jones N, Expression patterns of ShcD and Shc family adaptor proteins during mouse embryonic development. Dev Dyn. 2011 Jan;240(1):221-31 |
Shc2 SHC (Src homology 2 domain containing) transforming protein 2 (Synonyms: ShcB, Sli) | |
Results | Reference |
1* | J:166965 Hawley SP, Wills MK, Rabalski AJ, Bendall AJ, Jones N, Expression patterns of ShcD and Shc family adaptor proteins during mouse embryonic development. Dev Dyn. 2011 Jan;240(1):221-31 |
1* | J:66508 Sakai R, Henderson JT, O'Bryan JP, Elia AJ, Saxton TM, Pawson T, The mammalian ShcB and ShcC phosphotyrosine docking proteins function in the maturation of sensory and sympathetic neurons. Neuron. 2000 Dec;28(3):819-33 |
Shc3 src homology 2 domain-containing transforming protein C3 (Synonyms: N-Shc, Rai, ShcC) | |
Results | Reference |
1 | J:259892 Campbell DP, Chrysostomou E, Doetzlhofer A, Canonical Notch signaling plays an instructive role in auditory supporting cell development. Sci Rep. 2016 Jan 20;6:19484 |
1* | J:166965 Hawley SP, Wills MK, Rabalski AJ, Bendall AJ, Jones N, Expression patterns of ShcD and Shc family adaptor proteins during mouse embryonic development. Dev Dyn. 2011 Jan;240(1):221-31 |
Shc4 SHC (Src homology 2 domain containing) family, member 4 (Synonyms: 6230417E10Rik, 9930029B02Rik, LOC271849) | |
Results | Reference |
1* | J:166965 Hawley SP, Wills MK, Rabalski AJ, Bendall AJ, Jones N, Expression patterns of ShcD and Shc family adaptor proteins during mouse embryonic development. Dev Dyn. 2011 Jan;240(1):221-31 |
1* | J:194646 Turco MY, Furia L, Dietze A, Fernandez Diaz L, Ronzoni S, Sciullo A, Simeone A, Constam D, Faretta M, Lanfrancone L, Cellular heterogeneity during embryonic stem cell differentiation to epiblast stem cells is revealed by the ShcD/RaLP adaptor protein. Stem Cells. 2012 Nov;30(11):2423-36 |
Shcbp1 Shc SH2-domain binding protein 1 (Synonyms: mPAL) | |
Results | Reference |
1 | J:183920 Chen J, Lai F, Niswander L, The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling. Genes Dev. 2012 Apr 15;26(8):803-15 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Shh sonic hedgehog (Synonyms: Hhg1) | |
Results | Reference |
1 | J:350005 Adasooriya D, Jeong JK, Kyeong M, Kan S, Kim J, Cho ES, Cho SW, Notum regulates the cusp and root patterns in mouse molar. Sci Rep. 2024 Jun 13;14(1):13633 |
1* | J:198100 Andreeva V, Cardarelli J, Yelick PC, Rb1 mRNA expression in developing mouse teeth. Gene Expr Patterns. 2012 Mar-Apr;12(3-4):130-5 |
2 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
1 | J:149988 Beites CL, Hollenbeck PL, Kim J, Lovell-Badge R, Lander AD, Calof AL, Follistatin modulates a BMP autoregulatory loop to control the size and patterning of sensory domains in the developing tongue. Development. 2009 Jul;136(13):2187-97 |
1 | J:176604 Bell SM, Zhang L, Mendell A, Xu Y, Haitchi HM, Lessard JL, Whitsett JA, Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. Dev Biol. 2011 Oct 1;358(1):79-90 |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
2* | J:38383 Bellusci S, Furuta Y, Rush MG, Henderson R, Winnier G, Hogan BL, Involvement of Sonic hedgehog (Shh) in mouse embryonic lung growth and morphogenesis. Development. 1997 Jan;124(1):53-63 |
1* | J:88802 Berman DM, Desai N, Wang X, Karhadkar SS, Reynon M, Abate-Shen C, Beachy PA, Shen MM, Roles for Hedgehog signaling in androgen production and prostate ductal morphogenesis. Dev Biol. 2004 Mar 15;267(2):387-98 |
1* | J:29671 Bitgood MJ, McMahon AP, Hedgehog and Bmp genes are coexpressed at many diverse sites of cell-cell interaction in the mouse embryo. Dev Biol. 1995 Nov;172(1):126-38 |
1 | J:262819 Bohnenpoll T, Feraric S, Nattkemper M, Weiss AC, Rudat C, Meuser M, Trowe MO, Kispert A, Diversification of Cell Lineages in Ureter Development. J Am Soc Nephrol. 2017 Jun;28(6):1792-1801 |
1 | J:282102 Canizares MA, Albors AR, Singer G, Suttie N, Gorkic M, Felts P, Storey KG, Multiple steps characterise ventricular layer attrition to form the ependymal cell lining of the adult mouse spinal cord central canal. J Anat. 2019 Oct 31; |
1 | J:135168 Capurro MI, Xu P, Shi W, Li F, Jia A, Filmus J, Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding. Dev Cell. 2008 May;14(5):700-11 |
1* | J:21621 Chang DT, Lopez A, von Kessler DP, Chiang C, Simandl BK, Zhao R, Seldin MF, Fallon JF, Beachy PA, Products, genetic linkage and limb patterning activity of a murine hedgehog gene. Development. 1994 Nov;120(11):3339-53 |
1* | J:166178 Chen H, Yong W, Hinds TD Jr, Yang Z, Zhou Y, Sanchez ER, Shou W, Fkbp52 regulates androgen receptor transactivation activity and male urethra morphogenesis. J Biol Chem. 2010 Sep 3;285(36):27776-84 |
3 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1* | J:91052 Cobourne MT, Miletich I, Sharpe PT, Restriction of sonic hedgehog signalling during early tooth development. Development. 2004 Jun;131(12):2875-85 |
1* | J:150375 Cobourne MT, Xavier GM, Depew M, Hagan L, Sealby J, Webster Z, Sharpe PT, Sonic hedgehog signalling inhibits palatogenesis and arrests tooth development in a mouse model of the nevoid basal cell carcinoma syndrome. Dev Biol. 2009 Jul 1;331(1):38-49 |
1 | J:111051 Cui CY, Hashimoto T, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9142-7 |
1 | J:217500 Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D, Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60 |
1 | J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82 |
1* | J:16386 Echelard Y, Epstein DJ, St-Jacques B, Shen L, Mohler J, McMahon JA, McMahon AP, Sonic hedgehog, a member of a family of putative signaling molecules, is implicated in the regulation of CNS polarity. Cell. 1993 Dec 31;75(7):1417-30 |
1 | J:244957 El Shahawy M, Reibring CG, Neben CL, Hallberg K, Marangoni P, Harfe BD, Klein OD, Linde A, Gritli-Linde A, Cell fate specification in the lingual epithelium is controlled by antagonistic activities of Sonic hedgehog and retinoic acid. PLoS Genet. 2017 Jul;13(7):e1006914 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:163224 Garcia-Lopez M, Abellan A, Legaz I, Rubenstein JL, Puelles L, Medina L, Histogenetic compartments of the mouse centromedial and extended amygdala based on gene expression patterns during development. J Comp Neurol. 2008 Jan 1;506(1):46-74 |
1 | J:356109 Ge W, Tan SJ, Wang SH, Li L, Sun XF, Shen W, Wang X, Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development. Theranostics. 2020;10(17):7581-7598 |
1 | J:71184 Gritli-Linde A, Lewis P, McMahon AP, Linde A, The whereabouts of a morphogen: direct evidence for short- and graded long-range activity of hedgehog signaling peptides. Dev Biol. 2001 Aug 15;236(2):364-86 |
1* | J:75698 Grunder A, Ebel TT, Mallo M, Schwarzkopf G, Shimizu T, Sippel AE, Schrewe H, Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia. Mech Dev. 2002 Mar;112(1-2):69-77 |
1* | J:53317 Hall JM, Hooper JE, Finger TE, Expression of sonic hedgehog, patched, and Gli1 in developing taste papillae of the mouse. J Comp Neurol. 1999 Apr 5;406(2):143-55 |
1 | J:222425 Harada M, Omori A, Nakahara C, Nakagata N, Akita K, Yamada G, Tissue-specific roles of FGF signaling in external genitalia development. Dev Dyn. 2015 Jun;244(6):759-73 |
1 | J:217375 Heavner WE, Andoniadou CL, Pevny LH, Establishment of the neurogenic boundary of the mouse retina requires cooperation of SOX2 and WNT signaling. Neural Dev. 2014;9:27 |
1 | J:65293 Hebrok M, Kim SK, St Jacques B, McMahon AP, Melton DA, Regulation of pancreas development by hedgehog signaling. Development. 2000 Nov;127(22):4905-13 |
1 | J:241569 Higashiyama H, Ozawa A, Sumitomo H, Uemura M, Fujino K, Igarashi H, Imaimatsu K, Tsunekawa N, Hirate Y, Kurohmaru M, Saijoh Y, Kanai-Azuma M, Kanai Y, Embryonic cholecystitis and defective gallbladder contraction in the Sox17-haploinsufficient mouse model of biliary atresia. Development. 2017 May 15;144(10):1906-1917 |
1 | J:152851 Huang X, Ketova T, Fleming JT, Wang H, Dey SK, Litingtung Y, Chiang C, Sonic hedgehog signaling regulates a novel epithelial progenitor domain of the hindbrain choroid plexus. Development. 2009 Aug;136(15):2535-43 |
2 | J:160335 Huang X, Liu J, Ketova T, Fleming JT, Grover VK, Cooper MK, Litingtung Y, Chiang C, Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8422-7 |
2 | J:214032 Ishida K, Yuge Y, Hanaoka M, Yasukawa M, Minami Y, Ogawa M, Masumoto KH, Shigeyoshi Y, Saito M, Tsuji T, Gadd45g regulates dental epithelial cell proliferation through p38 MAPK-mediated p21 expression. Genes Cells. 2013 Aug;18(8):660-71 |
1 | J:108713 Itaranta P, Chi L, Seppanen T, Niku M, Tuukkanen J, Peltoketo H, Vainio S, Wnt-4 signaling is involved in the control of smooth muscle cell fate via Bmp-4 in the medullary stroma of the developing kidney. Dev Biol. 2006 May 15;293(2):473-83 |
1 | J:119729 Iwatsuki K, Liu HX, Gronder A, Singer MA, Lane TF, Grosschedl R, Mistretta CM, Margolskee RF, Wnt signaling interacts with Shh to regulate taste papilla development. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2253-8 |
1 | J:118173 Jarvinen E, Salazar-Ciudad I, Birchmeier W, Taketo MM, Jernvall J, Thesleff I, Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18627-32 |
1* | J:38389 Jensen AM, Wallace VA, Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina. Development. 1997 Jan;124(2):363-71 |
1 | J:170540 Jeong Y, Dolson DK, Waclaw RR, Matise MP, Sussel L, Campbell K, Kaestner KH, Epstein DJ, Spatial and temporal requirements for sonic hedgehog in the regulation of thalamic interneuron identity. Development. 2011 Feb;138(3):531-41 |
1 | J:233686 Jia WJ, Jiang S, Tang QL, Shen D, Xue B, Ning W, Li CJ, Geranylgeranyl Diphosphate Synthase Modulates Fetal Lung Branching Morphogenesis Possibly through Controlling K-Ras Prenylation. Am J Pathol. 2016 Jun;186(6):1454-65 |
1 | J:282774 Jia X, Min L, Zhu S, Zhang S, Huang X, Loss of sonic hedgehog gene leads to muscle development disorder and megaesophagus in mice. FASEB J. 2018 Oct;32(10):5703-5715 |
1 | J:260962 Kamiunten T, Ideno H, Shimada A, Arai Y, Terashima T, Tomooka Y, Nakamura Y, Nakashima K, Kimura H, Shinkai Y, Tachibana M, Nifuji A, Essential roles of G9a in cell proliferation and differentiation during tooth development. Exp Cell Res. 2017 Aug 15;357(2):202-210 |
1 | J:54912 Karlsson L, Bondjers C, Betsholtz C, Roles for PDGF-A and sonic hedgehog in development of mesenchymal components of the hair follicle. Development. 1999 Jun;126(12):2611-21 |
1* | J:260416 Kibe K, Nakatomi M, Kataoka S, Toyono T, Seta Y, Hey1 and Hey2 are differently expressed during mouse tooth development. Gene Expr Patterns. 2018 Jan;27:99-105 |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1 | J:155826 King P, Paul A, Laufer E, Shh signaling regulates adrenocortical development and identifies progenitors of steroidogenic lineages. Proc Natl Acad Sci U S A. 2009 Dec 15;106(50):21185-90 |
1 | J:130572 Klein OD, Lyons DB, Balooch G, Marshall GW, Basson MA, Peterka M, Boran T, Peterkova R, Martin GR, An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development. 2008 Jan;135(2):377-85 |
1 | J:151258 Kolterud A, Grosse AS, Zacharias WJ, Walton KD, Kretovich KE, Madison BB, Waghray M, Ferris JE, Hu C, Merchant JL, Dlugosz AA, Kottmann AH, Gumucio DL, Paracrine Hedgehog signaling in stomach and intestine: new roles for hedgehog in gastrointestinal patterning. Gastroenterology. 2009 Aug;137(2):618-28 |
1 | J:114152 Kuraguchi M, Wang XP, Bronson RT, Rothenberg R, Ohene-Baah NY, Lund JJ, Kucherlapati M, Maas RL, Kucherlapati R, Adenomatous Polyposis Coli (APC) is required for normal development of skin and thymus. PLoS Genet. 2006;2(9):e146 |
1 | J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670 |
1 | J:78990 Lamm ML, Catbagan WS, Laciak RJ, Barnett DH, Hebner CM, Gaffield W, Walterhouse D, Iannaccone P, Bushman W, Sonic hedgehog activates mesenchymal Gli1 expression during prostate ductal bud formation. Dev Biol. 2002 Sep 15;249(2):349-66 |
1 | J:69382 Lamm ML, Podlasek CA, Barnett DH, Lee J, Clemens JQ, Hebner CM, Bushman W, Mesenchymal factor bone morphogenetic protein 4 restricts ductal budding and branching morphogenesis in the developing prostate. Dev Biol. 2001 Apr 15;232(2):301-14 |
3 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
1* | J:326256 Lee JM, Qin C, Chai OH, Lan Y, Jiang R, Kwon HE, MSX1 Drives Tooth Morphogenesis Through Controlling Wnt Signaling Activity. J Dent Res. 2022 Jul;101(7):832-839 |
1 | J:178364 Lenton K, James AW, Manu A, Brugmann SA, Birker D, Nelson ER, Leucht P, Helms JA, Longaker MT, Indian hedgehog positively regulates calvarial ossification and modulates bone morphogenetic protein signaling. Genesis. 2011 Oct;49(10):784-96 |
1 | J:92189 Lewis PM, Gritli-Linde A, Smeyne R, Kottmann A, McMahon AP, Sonic hedgehog signaling is required for expansion of granule neuron precursors and patterning of the mouse cerebellum. Dev Biol. 2004 Jun 15;270(2):393-410 |
1 | J:214993 Lin C, Chen MH, Yao E, Song H, Gacayan R, Hui CC, Chuang PT, Differential regulation of Gli proteins by Sufu in the lung affects PDGF signaling and myofibroblast development. Dev Biol. 2014 Aug 15;392(2):324-33 |
1 | J:179217 Liu HX, Grosse AS, Iwatsuki K, Mishina Y, Gumucio DL, Mistretta CM, Separate and distinctive roles for Wnt5a in tongue, lingual tissue and taste papilla development. Dev Biol. 2012 Jan 1;361(1):39-56 |
1 | J:160591 Liu Z, Owen T, Zhang L, Zuo J, Dynamic expression pattern of Sonic hedgehog in developing cochlear spiral ganglion neurons. Dev Dyn. 2010 Jun;239(6):1674-83 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:321068 Maimets M, Pedersen MT, Guiu J, Dreier J, Thodberg M, Antoku Y, Schweiger PJ, Rib L, Bressan RB, Miao Y, Garcia KC, Sandelin A, Serup P, Jensen KB, Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling. Nat Commun. 2022 Feb 7;13(1):715 |
1 | J:137605 Manuel M, Pratt T, Liu M, Jeffery G, Price DJ, Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance. BMC Dev Biol. 2008;8:59 |
1 | J:348792 Mead TJ, Bhutada S, Foulcer SJ, Peruzzi N, Nelson CM, Seifert DE, Larkin J, Tran-Lundmark K, Filmus J, Apte SS, Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development. Matrix Biol. 2024 May 13; |
1 | J:218941 Meier F, Giesert F, Delic S, Faus-Kessler T, Matheus F, Simeone A, Holter SM, Kuhn R, Weisenhorn DM, Wurst W, Prakash N, FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS One. 2014;9(7):e101124 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1 | J:126364 Merchan P, Bribian A, Sanchez-Camacho C, Lezameta M, Bovolenta P, de Castro F, Sonic hedgehog promotes the migration and proliferation of optic nerve oligodendrocyte precursors. Mol Cell Neurosci. 2007 Nov;36(3):355-368 |
1* | J:86666 Michno K, Boras-Granic K, Mill P, Hui CC, Hamel PA, Shh expression is required for embryonic hair follicle but not mammary gland development. Dev Biol. 2003 Dec 1;264(1):153-65 |
1* | J:156970 Mikels A, Minami Y, Nusse R, Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling. J Biol Chem. 2009 Oct 30;284(44):30167-76 |
1 | J:100687 Mill P, Mo R, Hu MC, Dagnino L, Rosenblum ND, Hui CC, Shh controls epithelial proliferation via independent pathways that converge on N-Myc. Dev Cell. 2005 Aug;9(2):293-303 |
1* | J:73657 Miller LA, Wert SE, Whitsett JA, Immunolocalization of sonic hedgehog (Shh) in developing mouse lung. J Histochem Cytochem. 2001 Dec;49(12):1593-604 |
1 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1 | J:309402 Nakamura T, Jimenez-Rojo L, Koyama E, Pacifici M, de Vega S, Iwamoto M, Fukumoto S, Unda F, Yamada Y, Epiprofin Regulates Enamel Formation and Tooth Morphogenesis by Controlling Epithelial-Mesenchymal Interactions During Tooth Development. J Bone Miner Res. 2017 Mar;32(3):601-610 |
3* | J:137801 Nakayama A, Miura H, Shindo Y, Kusakabe Y, Tomonari H, Harada S, Expression of the basal cell markers of taste buds in the anterior tongue and soft palate of the mouse embryo. J Comp Neurol. 2008 Jul 10;509(2):211-24 |
1 | J:353047 Nevorankova P, Sulcova M, Kavkova M, Zimcik D, Balkova SM, Peleskova K, Kristekova D, Jakesova V, Zikmund T, Kaiser J, Hola LI, Kolar M, Buchtova M, Region-specific gene expression profiling of early mouse mandible uncovered SATB2 as a key molecule for teeth patterning. Sci Rep. 2024 Aug 6;14(1):18212 |
1* | J:297164 Nie X, Zheng J, Cruciger M, Yang P, Mao JJ, mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev Biol. 2020 Nov 1;467(1-2):77-87 |
1 | J:160263 Nielsen CM, Dymecki SM, Sonic hedgehog is required for vascular outgrowth in the hindbrain choroid plexus. Dev Biol. 2010 Apr 15;340(2):430-7 |
1 | J:144348 Ohazama A, Johnson EB, Ota MS, Choi HJ, Porntaveetus T, Oommen S, Itoh N, Eto K, Gritli-Linde A, Herz J, Sharpe PT, Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One. 2008;3(12):e4092 |
1 | J:183783 Ortega MC, Cases O, Merchan P, Kozyraki R, Clemente D, de Castro F, Megalin mediates the influence of sonic hedgehog on oligodendrocyte precursor cell migration and proliferation during development. Glia. 2012 May;60(6):851-66 |
1 | J:185279 Paces-Fessy M, Fabre M, Lesaulnier C, Cereghini S, Hnf1b and Pax2 cooperate to control different pathways in kidney and ureter morphogenesis. Hum Mol Genet. 2012 Jul 15;21(14):3143-55 |
1 | J:51967 Podlasek CA, Seo RM, Clemens JQ, Ma L, Maas RL, Bushman W, Hoxa-10 deficient male mice exhibit abnormal development of the accessory sex organs. Dev Dyn. 1999 Jan;214(1):1-12 |
1 | J:163175 Rice DP, Connor EC, Veltmaat JM, Lana-Elola E, Veistinen L, Tanimoto Y, Bellusci S, Rice R, Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation. Hum Mol Genet. 2010 Sep 1;19(17):3457-67 |
1 | J:117758 Sasaki Y, O'kane S, Dixon J, Dixon MJ, Ferguson MW, Temporal and spatial expression of Pax9 and Sonic hedgehog during development of normal mouse palates and cleft palates in TGF-beta3 null embryos. Arch Oral Biol. 2007 Mar;52(3):260-7 |
1 | J:167067 Seidel K, Ahn CP, Lyons D, Nee A, Ting K, Brownell I, Cao T, Carano RA, Curran T, Schober M, Fuchs E, Joyner A, Martin GR, de Sauvage FJ, Klein OD, Hedgehog signaling regulates the generation of ameloblast progenitors in the continuously growing mouse incisor. Development. 2010 Nov;137(22):3753-61 |
2* | J:85949 Shikama N, Lutz W, Kretzschmar R, Sauter N, Roth JF, Marino S, Wittwer J, Scheidweiler A, Eckner R, Essential function of p300 acetyltransferase activity in heart, lung and small intestine formation. EMBO J. 2003 Oct 1;22(19):5175-85 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:121421 Shu W, Lu MM, Zhang Y, Tucker PW, Zhou D, Morrisey EE, Foxp2 and Foxp1 cooperatively regulate lung and esophagus development. Development. 2007 May;134(10):1991-2000 |
1 | J:361958 Straube P, Beckers A, Jany UWH, Bergmann F, Ludtke TH, Rudat C, Trowe MO, Peters I, Klopf MG, Mamo TM, Kispert A, Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter. Development. 2025 Feb 1;152(3) |
1 | J:144194 Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72 |
1 | J:161718 Suzuki Y, Ikeda K, Kawakami K, Regulatory role of Six1 in the development of taste papillae. Cell Tissue Res. 2010 Mar;339(3):513-25 |
1 | J:288236 Takahashi M, Ikeda K, Ohmuraya M, Nakagawa Y, Sakuma T, Yamamoto T, Kawakami K, Six1 is required for signaling center formation and labial-lingual asymmetry in developing lower incisors. Dev Dyn. 2020 Apr 3; |
1 | J:159209 Tornqvist G, Sandberg A, Hagglund AC, Carlsson L, Cyclic expression of lhx2 regulates hair formation. PLoS Genet. 2010;6(4):e1000904 |
1 | J:149542 Wang XP, O'Connell DJ, Lund JJ, Saadi I, Kuraguchi M, Turbe-Doan A, Cavallesco R, Kim H, Park PJ, Harada H, Kucherlapati R, Maas RL, Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood. Development. 2009 Jun;136(11):1939-49 |
1 | J:91704 Wang XP, Suomalainen M, Jorgez CJ, Matzuk MM, Wankell M, Werner S, Thesleff I, Modulation of activin/bone morphogenetic protein signaling by follistatin is required for the morphogenesis of mouse molar teeth. Dev Dyn. 2004 Sep;231(1):98-108 |
1 | J:351706 Wang Y, Wang J, Xu T, Yang S, Wang X, Zhu L, Li N, Liu B, Xiao J, Liu C, Ectopic Activation of Fgf8 in Dental Mesenchyme Causes Incisor Agenesis and Molar Microdontia. Int J Mol Sci. 2024 Jun 27;25(13) |
1 | J:82377 Watkins DN, Berman DM, Burkholder SG, Wang B, Beachy PA, Baylin SB, Hedgehog signalling within airway epithelial progenitors and in small-cell lung cancer. Nature. 2003 Mar 20;422(6929):313-7 |
2 | J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26 |
1 | J:196290 Wheway G, Abdelhamed Z, Natarajan S, Toomes C, Inglehearn C, Johnson CA, Aberrant Wnt signalling and cellular over-proliferation in a novel mouse model of Meckel-Gruber syndrome. Dev Biol. 2013 May 1;377(1):55-66 |
1 | J:195784 Xavier GM, Panousopoulos L, Cobourne MT, Scube3 is expressed in multiple tissues during development but is dispensable for embryonic survival in the mouse. PLoS One. 2013;8(1):e55274 |
1 | J:234179 Xiao Y, Thoresen DT, Miao L, Williams JS, Wang C, Atit RP, Wong SY, Brownell I, A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development. PLoS Genet. 2016 Jul;12(7):e1006150 |
1* | J:332246 Xie F, Zhu X, Liu X, Chen H, Wang J, N6-methyladenosine (m6A) RNA methylation mediated by methyltransferase complex subunit WTAP regulates amelogenesis. J Biol Chem. 2022 Dec;298(12):102715 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
1 | J:140401 Xu X, Han J, Ito Y, Bringas P Jr, Deng C, Chai Y, Ectodermal Smad4 and p38 MAPK are functionally redundant in mediating TGF-beta/BMP signaling during tooth and palate development. Dev Cell. 2008 Aug;15(2):322-9 |
1 | J:116953 Yamago G, Takata Y, Furuta I, Urase K, Momoi T, Huh N, Suppression of hair follicle development inhibits induction of sonic hedgehog, patched, and patched-2 in hair germs in mice. Arch Dermatol Res. 2001 Sep;293(9):435-41 |
1 | J:309435 Zhang B, Tsai PC, Gonzalez-Celeiro M, Chung O, Boumard B, Perdigoto CN, Ezhkova E, Hsu YC, Hair follicles' transit-amplifying cells govern concurrent dermal adipocyte production through Sonic Hedgehog. Genes Dev. 2016 Oct 15;30(20):2325-2338 |
2 | J:328995 Zhang SF, Dai SK, Du HZ, Wang H, Li XG, Tang Y, Liu CM, The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis. Stem Cell Reports. 2022 Sep 13;17(9):2064-2080 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
1 | J:266585 Zheng J, Nie X, He L, Yoon AJ, Wu L, Zhang X, Vats M, Schiff MD, Xiang L, Tian Z, Ling J, Mao JJ, Epithelial Cdc42 Deletion Induced Enamel Organ Defects and Cystogenesis. J Dent Res. 2018 Nov;97(12):1346-1354 |
Shisa2 shisa family member 2 (Synonyms: 9430059P22Rik, MAd2, mShisa, shisa, Tmem46) | |
Results | Reference |
1 | J:259894 Onishi K, Zou Y, Sonic Hedgehog switches on Wnt/planar cell polarity signaling in commissural axon growth cones by reducing levels of Shisa2. Elife. 2017 Sep 8;6:e25269 |
Shisa3 shisa family member 3 (Synonyms: D830007B15Rik, mShisa3) | |
Results | Reference |
1 | J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005 |
Shisa8 shisa family member 8 (Synonyms: AI848285, CKAMP39, Orf26) | |
Results | Reference |
1* | J:306246 He M, Wu B, Ye W, Le DD, Sinclair AW, Padovano V, Chen Y, Li KX, Sit R, Tan M, Caplan MJ, Neff N, Jan YN, Darmanis S, Jan LY, Chloride channels regulate differentiation and barrier functions of the mammalian airway. Elife. 2020 Apr 14;9:e53085 |
Shoc1 shortage in chiasmata 1 (Synonyms: AI481877, Gm426, LOC242489, Mzip2) | |
Results | Reference |
1 | J:268520 Zhang Q, Shao J, Fan HY, Yu C, Evolutionarily-conserved MZIP2 is essential for crossover formation in mammalian meiosis. Commun Biol. 2018;1:147 |
Shox2 SHOX homeobox 2 (Synonyms: 6330543G17Rik, Og12x, Prx3) | |
Results | Reference |
1 | J:46173 Blaschke RJ, Monaghan AP, Schiller S, Schechinger B, Rao E, Padilla-Nash H, Ried T, Rappold GA, SHOT, a SHOX-related homeobox gene, is implicated in craniofacial, brain, heart, and limb development. Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2406-11 |
1* | J:146147 Espinoza-Lewis RA, Yu L, He F, Liu H, Tang R, Shi J, Sun X, Martin JF, Wang D, Yang J, Chen Y, Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5. Dev Biol. 2009 Mar 15;327(2):376-85 |
1 | J:191689 Gross S, Krause Y, Wuelling M, Vortkamp A, Hoxa11 and Hoxd11 regulate chondrocyte differentiation upstream of Runx2 and Shox2 in mice. PLoS One. 2012;7(8):e43553 |
1* | J:138379 Gu S, Wei N, Yu L, Fei J, Chen Y, Shox2-deficiency leads to dysplasia and ankylosis of the temporomandibular joint in mice. Mech Dev. 2008 Aug;125(8):729-42 |
1* | J:295958 Neupane S, Adhikari N, Jung JK, An CH, Lee S, Jun JH, Kim JY, Lee Y, Sohn WJ, Kim JY, Regulation of mesenchymal signaling in palatal mucosa differentiation. Histochem Cell Biol. 2018 Feb;149(2):143-152 |
1 | J:235118 Sun C, Yu D, Ye W, Liu C, Gu S, Sinsheimer NR, Song Z, Li X, Chen C, Song Y, Wang S, Schrader L, Chen Y, The short stature homeobox 2 (Shox2)-bone morphogenetic protein (BMP) pathway regulates dorsal mesenchymal protrusion development and its temporary function as a pacemaker during cardiogenesis. J Biol Chem. 2015 Jan 23;290(4):2007-23 |
1 | J:212095 Wang J, Bai Y, Li N, Ye W, Zhang M, Greene SB, Tao Y, Chen Y, Wehrens XH, Martin JF, Pitx2-microRNA pathway that delimits sinoatrial node development and inhibits predisposition to atrial fibrillation. Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9181-6 |
1 | J:226315 Ye W, Wang J, Song Y, Yu D, Sun C, Liu C, Chen F, Zhang Y, Wang F, Harvey RP, Schrader L, Martin JF, Chen Y, A common Shox2-Nkx2-5 antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node. Development. 2015 Jul 15;142(14):2521-32 |
Shq1 SHQ1 homolog (S. cerevisiae) (Synonyms: 2810403P18Rik, Grim-1) | |
Results | Reference |
1* | J:361610 Chang CH, Wong LC, Huang CW, Li YR, Yang CW, Tsai JW, Lee WT, Pathogenic SHQ1 variants result in disruptions to neuronal development and the dopaminergic pathway. Exp Neurol. 2024 Dec;382:114968 |
Shroom4 shroom family member 4 (Synonyms: D430043L16Rik, Shrm4) | |
Results | Reference |
1* | J:116398 Hagens O, Dubos A, Abidi F, Barbi G, Van Zutven L, Hoeltzenbein M, Tommerup N, Moraine C, Fryns JP, Chelly J, van Bokhoven H, Gecz J, Dollfus H, Ropers HH, Schwartz CE, de Cassia Stocco Dos Santos R, Kalscheuer V, Hanauer A, Disruptions of the novel KIAA1202 gene are associated with X-linked mental retardation. Hum Genet. 2006 Jan;118(5):578-90 |
Shtn1 shootin 1 (Synonyms: 4930506M07Rik, shootin1) | |
Results | Reference |
2 | J:272349 Baba K, Yoshida W, Toriyama M, Shimada T, Manning CF, Saito M, Kohno K, Trimmer JS, Watanabe R, Inagaki N, Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance. Elife. 2018 Aug 7;7:e34593 |
1 | J:270842 Minegishi T, Uesugi Y, Kaneko N, Yoshida W, Sawamoto K, Inagaki N, Shootin1b Mediates a Mechanical Clutch to Produce Force for Neuronal Migration. Cell Rep. 2018 Oct 16;25(3):624-639.e6 |
Siah1a siah E3 ubiquitin protein ligase 1A (Synonyms: Sinh1a) | |
Results | Reference |
1* | J:12699 Della NG, Senior PV, Bowtell DD, Isolation and characterisation of murine homologues of the Drosophila seven in absentia gene (sina). Development. 1993 Apr;117(4):1333-43 |
Siah2 siah E3 ubiquitin protein ligase 2 (Synonyms: Sinh2) | |
Results | Reference |
2* | J:12699 Della NG, Senior PV, Bowtell DD, Isolation and characterisation of murine homologues of the Drosophila seven in absentia gene (sina). Development. 1993 Apr;117(4):1333-43 |
Siglecg sialic acid binding Ig-like lectin G (Synonyms: A630096C01Rik, mSiglec-G) | |
Results | Reference |
1* | J:317552 Casey SC, Blumberg B, The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver. Mol Endocrinol. 2012 Jun;26(6):916-25 |
Siglech sialic acid binding Ig-like lectin H (Synonyms: 6430529G09Rik, Siglec-H) | |
Results | Reference |
1* | J:333946 Hattori Y, Kato D, Murayama F, Koike S, Asai H, Yamasaki A, Naito Y, Kawaguchi A, Konishi H, Prinz M, Masuda T, Wake H, Miyata T, CD206(+) macrophages transventricularly infiltrate the early embryonic cerebral wall to differentiate into microglia. Cell Rep. 2023 Feb 7;42(2):112092 |
Sik1 salt inducible kinase 1 (Synonyms: Msk, Snf1lk) | |
Results | Reference |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
Sik2 salt inducible kinase 2 (Synonyms: G630080D20Rik, Snf1lk2) | |
Results | Reference |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
Sik3 SIK family kinase 3 (Synonyms: 5730525O22Rik, 9030204A07Rik, mKIAA0999) | |
Results | Reference |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
Sim1 single-minded family bHLH transcription factor 1 (Synonyms: bHLHe14) | |
Results | Reference |
1* | J:31897 Fan CM, Kuwana E, Bulfone A, Fletcher CF, Copeland NG, Jenkins NA, Crews S, Martinez S, Puelles L, Rubenstein JL, Tessier-Lavigne M, Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome. Mol Cell Neurosci. 1996 Jan;7(1):1-16 |
2 | J:304355 Garcia-Calero E, Lopez-Gonzalez L, Martinez-de-la-Torre M, Fan CM, Puelles L, Sim1-expressing cells illuminate the origin and course of migration of the nucleus of the lateral olfactory tract in the mouse amygdala. Brain Struct Funct. 2021 Mar;226(2):519-562 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:120909 Xu C, Fan CM, Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1. Mol Endocrinol. 2007 May;21(5):1234-45 |
Sim2 single-minded family bHLH transcription factor 2 (Synonyms: bHLHe15) | |
Results | Reference |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1* | J:31897 Fan CM, Kuwana E, Bulfone A, Fletcher CF, Copeland NG, Jenkins NA, Crews S, Martinez S, Puelles L, Rubenstein JL, Tessier-Lavigne M, Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome. Mol Cell Neurosci. 1996 Jan;7(1):1-16 |
1 | J:76787 Goshu E, Jin H, Fasnacht R, Sepenski M, Michaud JL, Fan CM, Sim2 mutants have developmental defects not overlapping with those of Sim1 mutants. Mol Cell Biol. 2002 Jun;22(12):4147-57 |
1 | J:89548 Goshu E, Jin H, Lovejoy J, Marion JF, Michaud JL, Fan CM, Sim2 contributes to neuroendocrine hormone gene expression in the anterior hypothalamus. Mol Endocrinol. 2004 May;18(5):1251-62 |
1* | J:134028 Levesque BM, Zhou S, Shan L, Johnston P, Kong Y, Degan S, Sunday ME, NPAS1 regulates branching morphogenesis in embryonic lung. Am J Respir Cell Mol Biol. 2007 Apr;36(4):427-34 |
Sin3a transcriptional regulator, SIN3A (yeast) (Synonyms: mSin3A, Sin3) | |
Results | Reference |
2 | J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34 |
2* | J:281257 Witteveen JS, Willemsen MH, Dombroski TC, van Bakel NH, Nillesen WM, van Hulten JA, Jansen EJ, Verkaik D, Veenstra-Knol HE, van Ravenswaaij-Arts CM, Wassink-Ruiter JS, Vincent M, David A, Le Caignec C, Schieving J, Gilissen C, Foulds N, Rump P, Strom T, Cremer K, Zink AM, Engels H, de Munnik SA, Visser JE, Brunner HG, Martens GJ, Pfundt R, Kleefstra T, Kolk SM, Haploinsufficiency of MeCP2-interacting transcriptional co-repressor SIN3A causes mild intellectual disability by affecting the development of cortical integrity. Nat Genet. 2016 Aug;48(8):877-87 |
1 | J:242896 Yao C, Carraro G, Konda B, Guan X, Mizuno T, Chiba N, Kostelny M, Kurkciyan A, David G, McQualter JL, Stripp BR, Sin3a regulates epithelial progenitor cell fate during lung development. Development. 2017 Jul 15;144(14):2618-2628 |
Sinhcaf SIN3-HDAC complex associated factor (Synonyms: Fam60a, Pptcs1, Tera) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Sipa1l1 signal-induced proliferation-associated 1 like 1 (Synonyms: 4931426N11Rik, mKIAA0440, Spar) | |
Results | Reference |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Sirt1 sirtuin 1 (Synonyms: Sir2, Sir2alpha) | |
Results | Reference |
1 | J:248208 Hisahara S, Chiba S, Matsumoto H, Tanno M, Yagi H, Shimohama S, Sato M, Horio Y, Histone deacetylase SIRT1 modulates neuronal differentiation by its nuclear translocation. Proc Natl Acad Sci U S A. 2008 Oct 7;105(40):15599-604 |
1 | J:297808 Li B, Li M, Li X, Li H, Lai Y, Huang S, He X, Si X, Zheng H, Liao W, Liao Y, Bin J, Sirt1-inducible deacetylation of p21 promotes cardiomyocyte proliferation. Aging (Albany NY). 2019 Dec 26;11(24):12546-12567 |
4* | J:87352 Sakamoto J, Miura T, Shimamoto K, Horio Y, Predominant expression of Sir2alpha, an NAD-dependent histone deacetylase, in the embryonic mouse heart and brain. FEBS Lett. 2004 Jan 2;556(1-3):281-6 |
Sirt6 sirtuin 6 (Synonyms: 2810449N18Rik) | |
Results | Reference |
3 | J:344966 Wei Y, Wang X, Ma Z, Xiang P, Liu G, Yin B, Hou L, Shu P, Liu W, Peng X, Sirt6 regulates the proliferation of neural precursor cells and cortical neurogenesis in mice. iScience. 2024 Feb 16;27(2):108706 |
Sis sucrase isomaltase (Synonyms: 2010204N08Rik, Si-s, sucrase-isomaltase) | |
Results | Reference |
2 | J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90 |
1* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
1 | J:106280 Li ZS, Schmauss C, Cuenca A, Ratcliffe E, Gershon MD, Physiological modulation of intestinal motility by enteric dopaminergic neurons and the D2 receptor: analysis of dopamine receptor expression, location, development, and function in wild-type and knock-out mice. J Neurosci. 2006 Mar 8;26(10):2798-807 |
1 | J:42211 Tung J, Markowitz AJ, Silberg DG, Traber PG, Developmental expression of SI is regulated in transgenic mice by an evolutionarily conserved promoter. Am J Physiol. 1997 Jul;273(1 Pt 1):G83-92 |
Siva1 SIVA1, apoptosis-inducing factor (Synonyms: CD27bp) | |
Results | Reference |
1 | J:308690 Coccia E, Planells-Ferrer L, Badillos-Rodriguez R, Pascual M, Segura MF, Fernandez-Hernandez R, Lopez-Soriano J, Gari E, Soriano E, Barneda-Zahonero B, Moubarak RS, Perez-Garcia MJ, Comella JX, SIVA-1 regulates apoptosis and synaptic function by modulating XIAP interaction with the death receptor antagonist FAIM-L. Cell Death Dis. 2020 Feb 3;11(2):82 |
Six1 sine oculis-related homeobox 1 | |
Results | Reference |
1* | J:181471 Ahmed M, Wong EY, Sun J, Xu J, Wang F, Xu PX, Eya1-six1 interaction is sufficient to induce hair cell fate in the cochlea by activating atoh1 expression in cooperation with sox2. Dev Cell. 2012 Feb 14;22(2):377-90 |
2 | J:173840 El-Hashash AH, Al Alam D, Turcatel G, Rogers O, Li X, Bellusci S, Warburton D, Six1 transcription factor is critical for coordination of epithelial, mesenchymal and vascular morphogenesis in the mammalian lung. Dev Biol. 2011 May 15;353(2):242-58 |
1* | J:170495 Ikeda K, Kageyama R, Suzuki Y, Kawakami K, Six1 is indispensable for production of functional progenitor cells during olfactory epithelial development. Int J Dev Biol. 2010;54(10):1453-64 |
1* | J:126356 Ikeda K, Ookawara S, Sato S, Ando Z, Kageyama R, Kawakami K, Six1 is essential for early neurogenesis in the development of olfactory epithelium. Dev Biol. 2007 Nov 1;311(1):53-68 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:321428 Kruber P, Angay O, Winkler A, Bosl MR, Kneitz S, Heinze KG, Gessler M, Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation. Int J Cancer. 2019 Mar 15;144(6):1391-1400 |
1 | J:159508 Nonomura K, Takahashi M, Wakamatsu Y, Takano-Yamamoto T, Osumi N, Dynamic expression of Six family genes in the dental mesenchyme and the epithelial ameloblast stem/progenitor cells during murine tooth development. J Anat. 2010 Jan;216(1):80-91 |
1 | J:161718 Suzuki Y, Ikeda K, Kawakami K, Regulatory role of Six1 in the development of taste papillae. Cell Tissue Res. 2010 Mar;339(3):513-25 |
1* | J:320689 Xu J, Li J, Ramakrishnan A, Yan H, Shen L, Xu PX, Six1 and Six2 of the Sine Oculis Homeobox Subfamily are Not Functionally Interchangeable in Mouse Nephron Formation. Front Cell Dev Biol. 2022;10:815249 |
1 | J:225537 Zhang J, Taylor RJ, La Torre A, Wilken MS, Cox KE, Reh TA, Vetter ML, Ezh2 maintains retinal progenitor proliferation, transcriptional integrity, and the timing of late differentiation. Dev Biol. 2015 Jul 15;403(2):128-38 |
Six2 sine oculis-related homeobox 2 | |
Results | Reference |
1 | J:315767 Ahn SY, Kim Y, Kim ST, Swat W, Miner JH, Scaffolding proteins DLG1 and CASK cooperate to maintain the nephron progenitor population during kidney development. J Am Soc Nephrol. 2013 Jun;24(7):1127-38 |
1 | J:332930 Anderson MJ, Misaghian S, Sharma N, Perantoni AO, Lewandoski M, Fgf8 promotes survival of nephron progenitors by regulating BAX/BAK-mediated apoptosis. Differentiation. 2022 Dec 6;130:7-15 |
1 | J:185582 Barak H, Huh SH, Chen S, Jeanpierre C, Martinovic J, Parisot M, Bole-Feysot C, Nitschke P, Salomon R, Antignac C, Ornitz DM, Kopan R, FGF9 and FGF20 Maintain the Stemness of Nephron Progenitors in Mice and Man. Dev Cell. 2012 Jun 12;22(6):1191-207 |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
2 | J:355647 Bugacov H, Der B, Briantseva BM, Guo Q, Kim S, Lindstrom NO, McMahon AP, Dose-dependent responses to canonical Wnt transcriptional complexes in the regulation of mammalian nephron progenitors. Development. 2024 Sep 15;151(18) |
1 | J:237525 Chung E, Deacon P, Marable S, Shin J, Park JS, Notch signaling promotes nephrogenesis by downregulating Six2. Development. 2016 Nov 01;143(21):3907-3913 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1* | J:343078 Diniz F, Ngo NYN, Colon-Leyva M, Edgington-Giordano F, Hilliard S, Zwezdaryk K, Liu J, El-Dahr SS, Tortelote GG, Acetyl-CoA is a key molecule for nephron progenitor cell pool maintenance. Nat Commun. 2023 Nov 25;14(1):7733 |
1 | J:153202 Gerber SD, Steinberg F, Beyeler M, Villiger PM, Trueb B, The murine Fgfrl1 receptor is essential for the development of the metanephric kidney. Dev Biol. 2009 Nov 1;335(1):106-19 |
1* | J:310454 Gu Y, Zhao Y, Zhou Y, Xie Y, Ju P, Long Y, Liu J, Ni D, Cao F, Lyu Z, Mao Z, Hao J, Li Y, Wan Q, Kanyomse Q, Liu Y, Ren D, Ning Y, Li X, Zhou Q, Li B, Zeb1 Is a Potential Regulator of Six2 in the Proliferation, Apoptosis and Migration of Metanephric Mesenchyme Cells. Int J Mol Sci. 2016 Aug 6;17(8):1283 |
1* | J:207609 Hilliard SA, Yao X, El-Dahr SS, Mdm2 is required for maintenance of the nephrogenic niche. Dev Biol. 2014 Mar 1;387(1):1-14 |
1* | J:326010 Kanda S, Ohmuraya M, Akagawa H, Horita S, Yoshida Y, Kaneko N, Sugawara N, Ishizuka K, Miura K, Harita Y, Yamamoto T, Oka A, Araki K, Furukawa T, Hattori M, Deletion in the Cobalamin Synthetase W Domain-Containing Protein 1 Gene Is associated with Congenital Anomalies of the Kidney and Urinary Tract. J Am Soc Nephrol. 2020 Jan;31(1):139-147 |
1 | J:321428 Kruber P, Angay O, Winkler A, Bosl MR, Kneitz S, Heinze KG, Gessler M, Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation. Int J Cancer. 2019 Mar 15;144(6):1391-1400 |
1 | J:306027 Li H, Kurtzeborn K, Kupari J, Gui Y, Siefker E, Lu B, Matlik K, Olfat S, Montano-Rodriguez AR, Huh SH, Costantini F, Andressoo JO, Kuure S, Postnatal prolongation of mammalian nephrogenesis by excess fetal GDNF. Development. 2021 May 15;148(10):dev197475 |
1* | J:330216 Li J, Cheng C, Xu J, Zhang T, Tokat B, Dolios G, Ramakrishnan A, Shen L, Wang R, Xu PX, The transcriptional coactivator Eya1 exerts transcriptional repressive activity by interacting with REST corepressors and REST-binding sequences to maintain nephron progenitor identity. Nucleic Acids Res. 2022 Oct 14;50(18):10343-10359 |
1 | J:330416 Li J, Xu J, Jiang H, Zhang T, Ramakrishnan A, Shen L, Xu PX, Chromatin Remodelers Interact with Eya1 and Six2 to Target Enhancers to Control Nephron Progenitor Cell Maintenance. J Am Soc Nephrol. 2021 Nov;32(11):2815-2833 |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1* | J:263032 Magella B, Mahoney R, Adam M, Potter SS, Reduced Abd-B Hox function during kidney development results in lineage infidelity. Dev Biol. 2018 Jun 15;438(2):84-93 |
1 | J:239657 Mao Y, Francis-West P, Irvine KD, Fat4/Dchs1 signaling between stromal and cap mesenchyme cells influences nephrogenesis and ureteric bud branching. Development. 2015 Aug 01;142(15):2574-85 |
2 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
1 | J:347984 Naillat F, Deshar G, Hankkila A, Rak-Raszewska A, Sharma A, Prunskaite-Hyyrylainen R, Railo A, Shan J, Vainio SJ, Calcium signaling induces partial EMT and renal fibrosis in a Wnt4(mCherry) knock-in mouse model. Biochim Biophys Acta Mol Basis Dis. 2024 Apr 21;1870(5):167180 |
1 | J:309384 Neirijnck Y, Reginensi A, Renkema KY, Massa F, Kozlov VM, Dhib H, Bongers EMHF, Feitz WF, van Eerde AM, Lefebvre V, Knoers NVAM, Tabatabaei M, Schulz H, McNeill H, Schaefer F, Wegner M, Sock E, Schedl A, Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT). Kidney Int. 2018 May;93(5):1142-1153 |
1 | J:159508 Nonomura K, Takahashi M, Wakamatsu Y, Takano-Yamamoto T, Osumi N, Dynamic expression of Six family genes in the dental mesenchyme and the epithelial ameloblast stem/progenitor cells during murine tooth development. J Anat. 2010 Jan;216(1):80-91 |
3 | J:264647 O'Brien LL, Guo Q, Bahrami-Samani E, Park JS, Hasso SM, Lee YJ, Fang A, Kim AD, Guo J, Hong TM, Peterson KA, Lozanoff S, Raviram R, Ren B, Fogelgren B, Smith AD, Valouev A, McMahon AP, Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies. PLoS Genet. 2018 Jan;14(1):e1007181 |
2 | J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005 |
2 | J:349014 Rinta-Jaskari MM, Naillat F, Ruotsalainen HJ, Ronkainen VP, Heljasvaara R, Akram SU, Izzi V, Miinalainen I, Vainio SJ, Pihlajaniemi TA, Collagen XVIII regulates extracellular matrix integrity in the developing nephrons and impacts nephron progenitor cell behavior. Matrix Biol. 2024 May 22; |
1 | J:331052 Sharma A, Meer M, Dapkunas A, Ihermann-Hella A, Kuure S, Vainio SJ, Iber D, Naillat F, FGF8 induces chemokinesis and regulates condensation of mouse nephron progenitor cells. Development. 2022 Nov 1;149(21):dev201012 |
1* | J:285711 Sweat YY, Sweat M, Mansaray M, Cao H, Eliason S, Adeyemo WL, Gowans LJJ, Eshete MA, Anand D, Chalkley C, Saadi I, Lachke SA, Butali A, Amendt BA, Six2 regulates Pax9 expression, palatogenesis and craniofacial bone formation. Dev Biol. 2020 Feb 15;458(2):246-256 |
1 | J:326979 Taglienti M, Graf D, Schumacher V, Kreidberg JA, Bmp7 drives proximal tubule expansion and determines nephron number in the developing kidney. Development. 2022 Jul 15;149(14):dev200773 |
1 | J:345132 Umar M, Dong C, He F, Characterizing expression pattern of Six2Cre during mouse craniofacial development. Genesis. 2023 Sep;61(5):e23516 |
1* | J:320689 Xu J, Li J, Ramakrishnan A, Yan H, Shen L, Xu PX, Six1 and Six2 of the Sine Oculis Homeobox Subfamily are Not Functionally Interchangeable in Mouse Nephron Formation. Front Cell Dev Biol. 2022;10:815249 |
1 | J:208647 Xu J, Liu H, Park JS, Lan Y, Jiang R, Osr1 acts downstream of and interacts synergistically with Six2 to maintain nephron progenitor cells during kidney organogenesis. Development. 2014 Apr;141(7):1442-52 |
1 | J:363737 Xue Z, Xuan H, Lau K, Su Y, Wegener M, Li K, Turner L, Adams M, Shi X, Wen H, Expression of ENL YEATS domain tumor mutations in nephrogenic or stromal lineage impairs kidney development. Nat Commun. 2025 Mar 14;16(1):2531 |
1 | J:270550 Yermalovich AV, Osborne JK, Sousa P, Han A, Kinney MA, Chen MJ, Robinton DA, Montie H, Pearson DS, Wilson SB, Combes AN, Little MH, Daley GQ, Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis. Nat Commun. 2019 Jan 11;10(1):168 |
Six3 sine oculis-related homeobox 3 (Synonyms: E130112M24Rik) | |
Results | Reference |
1 | J:334460 Bando H, Brinkmeier ML, Castinetti F, Fang Q, Lee MS, Saveanu A, Albarel F, Dupuis C, Brue T, Camper SA, Heterozygous variants in SIX3 and POU1F1 cause pituitary hormone deficiency in mouse and man. Hum Mol Genet. 2023 Jan 13;32(3):367-385 |
1 | J:188155 Bharti K, Gasper M, Ou J, Brucato M, Clore-Gronenborn K, Pickel J, Arnheiter H, A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development. PLoS Genet. 2012 Jul;8(7):e1002757 |
1 | J:297714 Brignani S, Raj DDA, Schmidt ERE, Dudukcu O, Adolfs Y, De Ruiter AA, Rybiczka-Tesulov M, Verhagen MG, van der Meer C, Broekhoven MH, Moreno-Bravo JA, Grossouw LM, Dumontier E, Cloutier JF, Chedotal A, Pasterkamp RJ, Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development. Neuron. 2020 Aug 19;107(4):684-702.e9 |
1 | J:304355 Garcia-Calero E, Lopez-Gonzalez L, Martinez-de-la-Torre M, Fan CM, Puelles L, Sim1-expressing cells illuminate the origin and course of migration of the nucleus of the lateral olfactory tract in the mouse amygdala. Brain Struct Funct. 2021 Mar;226(2):519-562 |
1 | J:178674 Lavado A, Oliver G, Six3 is required for ependymal cell maturation. Development. 2011 Dec;138(24):5291-300 |
1 | J:137605 Manuel M, Pratt T, Liu M, Jeffery G, Price DJ, Overexpression of Pax6 results in microphthalmia, retinal dysplasia and defective retinal ganglion cell axon guidance. BMC Dev Biol. 2008;8:59 |
1 | J:196051 Moldrich RX, Gobius I, Pollak T, Zhang J, Ren T, Brown L, Mori S, De Juan Romero C, Britanova O, Tarabykin V, Richards LJ, Molecular regulation of the developing commissural plate. J Comp Neurol. 2010 Sep 15;518(18):3645-61 |
1 | J:159508 Nonomura K, Takahashi M, Wakamatsu Y, Takano-Yamamoto T, Osumi N, Dynamic expression of Six family genes in the dental mesenchyme and the epithelial ameloblast stem/progenitor cells during murine tooth development. J Anat. 2010 Jan;216(1):80-91 |
1* | J:177132 Rapicavoli NA, Poth EM, Zhu H, Blackshaw S, The long noncoding RNA Six3OS acts in trans to regulate retinal development by modulating Six3 activity. Neural Dev. 2011;6:32 |
1 | J:328873 Shang Z, Yang L, Wang Z, Tian Y, Gao Y, Su Z, Guo R, Li W, Liu G, Li X, Yang Z, Li Z, Zhang Z, The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity. Front Cell Dev Biol. 2022;10:948331 |
1 | J:350099 Song X, Chen H, Shang Z, Du H, Li Z, Wen Y, Liu G, Qi D, You Y, Yang Z, Zhang Z, Xu Z, Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons. Neurosci Bull. 2021 Jul;37(7):985-998 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
2 | J:264125 Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z, SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. Development. 2018 Jul 23;145(14):dev165456 |
1 | J:363737 Xue Z, Xuan H, Lau K, Su Y, Wegener M, Li K, Turner L, Adams M, Shi X, Wen H, Expression of ENL YEATS domain tumor mutations in nephrogenic or stromal lineage impairs kidney development. Nat Commun. 2025 Mar 14;16(1):2531 |
1* | J:353361 Yu H, Chiang A, Rubinstein M, Low MJ, The homeodomain transcription factor Six3 regulates hypothalamic Pomc expression and its absence from POMC neurons induces hyperphagia and mild obesity in male mice. Mol Metab. 2024 Sep;87:101993 |
1 | J:319845 Yu H, Rubinstein M, Low MJ, Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes. Elife. 2022 Jan 19;11:e72883 |
Six3os1 SIX homeobox 3, opposite strand 1 (Synonyms: D17Mgi26, E130112H22Rik, Rncr1) | |
Results | Reference |
1* | J:177132 Rapicavoli NA, Poth EM, Zhu H, Blackshaw S, The long noncoding RNA Six3OS acts in trans to regulate retinal development by modulating Six3 activity. Neural Dev. 2011;6:32 |
1 | J:350099 Song X, Chen H, Shang Z, Du H, Li Z, Wen Y, Liu G, Qi D, You Y, Yang Z, Zhang Z, Xu Z, Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons. Neurosci Bull. 2021 Jul;37(7):985-998 |
Six4 sine oculis-related homeobox 4 (Synonyms: AREC3, TrexBF) | |
Results | Reference |
1 | J:159508 Nonomura K, Takahashi M, Wakamatsu Y, Takano-Yamamoto T, Osumi N, Dynamic expression of Six family genes in the dental mesenchyme and the epithelial ameloblast stem/progenitor cells during murine tooth development. J Anat. 2010 Jan;216(1):80-91 |
1 | J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005 |
1* | J:190431 Suzuki Y, Ikeda K, Kawakami K, Development of gustatory papillae in the absence of Six1 and Six4. J Anat. 2011 Dec;219(6):710-21 |
Six5 sine oculis-related homeobox 5 (Synonyms: Dmahp, MDMAHP, TrexBF) | |
Results | Reference |
1 | J:159508 Nonomura K, Takahashi M, Wakamatsu Y, Takano-Yamamoto T, Osumi N, Dynamic expression of Six family genes in the dental mesenchyme and the epithelial ameloblast stem/progenitor cells during murine tooth development. J Anat. 2010 Jan;216(1):80-91 |
Six6 sine oculis-related homeobox 6 (Synonyms: Optx2, Six9) | |
Results | Reference |
1 | J:188155 Bharti K, Gasper M, Ou J, Brucato M, Clore-Gronenborn K, Pickel J, Arnheiter H, A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development. PLoS Genet. 2012 Jul;8(7):e1002757 |
1 | J:185560 Lee B, Rizzoti K, Kwon DS, Kim SY, Oh S, Epstein DJ, Son Y, Yoon J, Baek K, Jeong Y, Direct transcriptional regulation of Six6 is controlled by SoxB1 binding to a remote forebrain enhancer. Dev Biol. 2012 Jun 15;366(2):393-403 |
1* | J:74240 Mui SH, Hindges R, O'Leary DD, Lemke G, Bertuzzi S, The homeodomain protein Vax2 patterns the dorsoventral and nasotemporal axes of the eye. Development. 2002 Feb;129(3):797-804 |
1 | J:159508 Nonomura K, Takahashi M, Wakamatsu Y, Takano-Yamamoto T, Osumi N, Dynamic expression of Six family genes in the dental mesenchyme and the epithelial ameloblast stem/progenitor cells during murine tooth development. J Anat. 2010 Jan;216(1):80-91 |
1 | J:319845 Yu H, Rubinstein M, Low MJ, Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes. Elife. 2022 Jan 19;11:e72883 |
Ska3 spindle and kinetochore associated complex subunit 3 (Synonyms: F630043A04Rik) | |
Results | Reference |
1* | J:314146 Gao W, Zhang Y, Luo H, Niu M, Zheng X, Hu W, Cui J, Xue X, Bo Y, Dai F, Lu Y, Yang D, Guo Y, Guo H, Li H, Zhang Y, Yang T, Li L, Zhang L, Hou R, Wen S, An C, Ma T, Jin L, Xu W, Wu Y, Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis. Cell Death Dis. 2020 Oct 26;11(10):919 |
Ski ski sarcoma viral oncogene homolog (avian) (Synonyms: 2310012I02Rik, 2610001A11Rik, MGC:8300) | |
Results | Reference |
3 | J:196581 Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G, The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-beta signaling. Dev Biol. 2013 May 15;377(2):415-27 |
1 | J:21947 Lyons GE, Micales BK, Herr MJ, Horrigan SK, Namciu S, Shardy D, Stavnezer E, Protooncogene c-ski is expressed in both proliferating and postmitotic neuronal populations. Dev Dyn. 1994 Dec;201(4):354-65 |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
1 | J:29515 Namciu S, Lyons GE, Micales BK, Heyman HC, Colmenares C, Stavnezer E, Enhanced expression of mouse c-ski accompanies terminal skeletal muscle differentiation in vivo and in vitro. Dev Dyn. 1995 Nov;204(3):291-300 |
Skil SKI-like (Synonyms: 9130011J04Rik, Skir, sno-dE3, SnoN, SnoN2) | |
Results | Reference |
1* | J:31157 Pelzer T, Lyons GE, Kim S, Moreadith RW, Cloning and characterization of the murine homolog of the sno proto-oncogene reveals a novel splice variant. Dev Dyn. 1996 Feb;205(2):114-25 |
Skor2 SKI family transcriptional corepressor 2 (Synonyms: Corl2, Fussel18, Gm7348) | |
Results | Reference |
1 | J:184000 Baubet V, Xiang C, Molczan A, Roccograndi L, Melamed S, Dahmane N, Rp58 is essential for the growth and patterning of the cerebellum and for glutamatergic and GABAergic neuron development. Development. 2012 Jun;139(11):1903-9 |
1 | J:302307 Tran-Anh K, Zhang J, Nguyen-Minh VT, Fujita H, Hirata T, Sugihara I, Common Origin of the Cerebellar Dual Somatotopic Areas Revealed by Tracking Embryonic Purkinje Cell Clusters with Birthdate Tagging. eNeuro. 2020 Nov/Dec;7(6):ENEURO.0251-20.2020 |
1* | J:251975 Vibulyaseck S, Fujita H, Luo Y, Tran AK, Oh-Nishi A, Ono Y, Hirano S, Sugihara I, Spatial rearrangement of Purkinje cell subsets forms the transverse and longitudinal compartmentalization in the mouse embryonic cerebellum. J Comp Neurol. 2017 Oct 1;525(14):2971-2990 |
Skp1 S-phase kinase-associated protein 1 (Synonyms: 2610043E24Rik, 2610206H23Rik, p19Skp1, Skp1a, Tceb1l) | |
Results | Reference |
2 | J:325094 Guan Y, Lin H, Leu NA, Ruthel G, Fuchs SY, Busino L, Luo M, Wang PJ, SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination. Nucleic Acids Res. 2022 May 20;50(9):5129-5144 |
Skp2 S-phase kinase-associated protein 2 (Synonyms: 4930500A04Rik, FBXL1) | |
Results | Reference |
2 | J:320759 Yamauchi Y, Nita A, Nishiyama M, Muto Y, Shimizu H, Nakatsumi H, Nakayama KI, Skp2 contributes to cell cycle progression in trophoblast stem cells and to placental development. Genes Cells. 2020 Jun;25(6):427-438 |
Slc1a3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 (Synonyms: B430115D02Rik, Eaat1, GLAST, Gmt1, MGluT1) | |
Results | Reference |
2* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
1* | J:89775 Anthony TE, Klein C, Fishell G, Heintz N, Radial glia serve as neuronal progenitors in all regions of the central nervous system. Neuron. 2004 Mar 25;41(6):881-90 |
1* | J:142365 Barry G, Piper M, Lindwall C, Moldrich R, Mason S, Little E, Sarkar A, Tole S, Gronostajski RM, Richards LJ, Specific glial populations regulate hippocampal morphogenesis. J Neurosci. 2008 Nov 19;28(47):12328-40 |
1 | J:183848 Benadiba C, Magnani D, Niquille M, Morle L, Valloton D, Nawabi H, Ait-Lounis A, Otsmane B, Reith W, Theil T, Hornung JP, Lebrand C, Durand B, The ciliogenic transcription factor RFX3 regulates early midline distribution of guidepost neurons required for corpus callosum development. PLoS Genet. 2012 Mar;8(3):e1002606 |
1* | J:237193 Chaboub LS, Manalo JM, Lee HK, Glasgow SM, Chen F, Kawasaki Y, Akiyama T, Kuo CT, Creighton CJ, Mohila CA, Deneen B, Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury. J Neurosci. 2016 Nov 23;36(47):11904-11917 |
1 | J:240770 Gobius I, Morcom L, Suarez R, Bunt J, Bukshpun P, Reardon W, Dobyns WB, Rubenstein JL, Barkovich AJ, Sherr EH, Richards LJ, Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum. Cell Rep. 2016 Oct 11;17(3):735-747 |
1* | J:243644 Gobius I, Suarez R, Morcom L, Paolino A, Edwards TJ, Kozulin P, Richards LJ, Astroglial-mediated remodeling of the interhemispheric midline during telencephalic development is exclusive to eutherian mammals. Neural Dev. 2017 May 30;12(1):9 |
1 | J:126335 Hack I, Hellwig S, Junghans D, Brunne B, Bock HH, Zhao S, Frotscher M, Divergent roles of ApoER2 and Vldlr in the migration of cortical neurons. Development. 2007 Nov;134(21):3883-91 |
1 | J:67408 Hartfuss E, Galli R, Heins N, Gotz M, Characterization of CNS precursor subtypes and radial glia. Dev Biol. 2001 Jan 1;229(1):15-30 |
1 | J:259186 Heng X, Guo Q, Leung AW, Li JY, Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6:e23253 |
1 | J:126325 Komine O, Nagaoka M, Watase K, Gutmann DH, Tanigaki K, Honjo T, Radtke F, Saito T, Chiba S, Tanaka K, The monolayer formation of Bergmann glial cells is regulated by Notch/RBP-J signaling. Dev Biol. 2007 Nov 1;311(1):238-250 |
1 | J:205567 Li K, Leung AW, Guo Q, Yang W, Li JY, Shp2-Dependent ERK Signaling Is Essential for Induction of Bergmann Glia and Foliation of the Cerebellum. J Neurosci. 2014 Jan 15;34(3):922-31 |
1 | J:136385 Li S, Jin Z, Koirala S, Bu L, Xu L, Hynes RO, Walsh CA, Corfas G, Piao X, GPR56 regulates pial basement membrane integrity and cortical lamination. J Neurosci. 2008 May 28;28(22):5817-26 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:217046 Magnani D, Hasenpusch-Theil K, Benadiba C, Yu T, Basson MA, Price DJ, Lebrand C, Theil T, Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Cereb Cortex. 2014 Jan;24(1):186-98 |
1 | J:177840 Magri L, Cambiaghi M, Cominelli M, Alfaro-Cervello C, Cursi M, Pala M, Bulfone A, Garcia-Verdugo JM, Leocani L, Minicucci F, Poliani PL, Galli R, Sustained Activation of mTOR Pathway in Embryonic Neural Stem Cells Leads to Development of Tuberous Sclerosis Complex-Associated Lesions. Cell Stem Cell. 2011 Nov 4;9(5):447-62 |
1 | J:252094 Matuzelski E, Bunt J, Harkins D, Lim JWC, Gronostajski RM, Richards LJ, Harris L, Piper M, Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord. Dev Biol. 2017 Dec 15;432(2):286-297 |
1 | J:275078 Minocha S, Valloton D, Arsenijevic Y, Cardinaux JR, Guidi R, Hornung JP, Lebrand C, Nkx2.1 regulates the generation of telencephalic astrocytes during embryonic development. Sci Rep. 2017 Mar 7;7:43093 |
1 | J:269506 Minocha S, Valloton D, Brunet I, Eichmann A, Hornung JP, Lebrand C, NG2 glia are required for vessel network formation during embryonic development. Elife. 2015 Dec 10;4:e09102 |
1 | J:304719 Morcom L, Gobius I, Marsh AP, Suarez R, Lim JW, Bridges C, Ye Y, Fenlon LR, Zagar Y, Douglass AM, Donahoo AL, Fothergill T, Shaikh S, Kozulin P, Edwards TJ, Cooper HM, Sherr EH, Chedotal A, Leventer RJ, Lockhart PJ, Richards LJ, DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation. Elife. 2021 Apr 19;10:e61769 |
1 | J:131109 Ohkubo Y, Uchida AO, Shin D, Partanen J, Vaccarino FM, Fibroblast growth factor receptor 1 is required for the proliferation of hippocampal progenitor cells and for hippocampal growth in mouse. J Neurosci. 2004 Jul 7;24(27):6057-69 |
2 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:160038 Piper M, Moldrich RX, Lindwall C, Little E, Barry G, Mason S, Sunn N, Kurniawan ND, Gronostajski RM, Richards LJ, Multiple non-cell-autonomous defects underlie neocortical callosal dysgenesis in Nfib-deficient mice. Neural Dev. 2009;4:43 |
1 | J:84301 Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M, The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 2003 Jul 1;17(13):1677-89 |
1 | J:238248 Wang L, Hou S, Han YG, Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex. Nat Neurosci. 2016 Jul;19(7):888-96 |
1 | J:223471 Zhao X, Chen Y, Zhu Q, Huang H, Teng P, Zheng K, Hu X, Xie B, Zhang Z, Sander M, Qiu M, Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor. PLoS One. 2014;9(10):e109171 |
Slc2a1 solute carrier family 2 (facilitated glucose transporter), member 1 (Synonyms: Glut-1, Glut1, M100200, Rgsc200) | |
Results | Reference |
1 | J:346910 Ayyangar U, Karkhanis A, Tay H, Afandi AFB, Bhattacharjee O, Ks L, Lee SH, Chan J, Raghavan S, Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin. EMBO J. 2024 Apr;43(7):1113-1134 |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
1 | J:121238 Ganguly A, McKnight RA, Raychaudhuri S, Shin BC, Ma Z, Moley K, Devaskar SU, Glucose transporter isoform-3 mutations cause early pregnancy loss and fetal growth restriction. Am J Physiol Endocrinol Metab. 2007 May;292(5):E1241-55 |
1* | J:78912 Hellstrom M, Gerhardt H, Kalen M, Li X, Eriksson U, Wolburg H, Betsholtz C, Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol. 2001 Apr 30;153(3):543-53 |
2 | J:294228 Kalailingam P, Wang KQ, Toh XR, Nguyen TQ, Chandrakanthan M, Hasan Z, Habib C, Schif A, Radio FC, Dallapiccola B, Weiss K, Nguyen LN, Deficiency of MFSD7c results in microcephaly-associated vasculopathy in Fowler syndrome. J Clin Invest. 2020 Aug 3;130(8):4081-4093 |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1 | J:268341 Lee SY, Abel ED, Long F, Glucose metabolism induced by Bmp signaling is essential for murine skeletal development. Nat Commun. 2018 Nov 16;9(1):4831 |
1* | J:326531 Li Y, Yang S, Liu Y, Qin L, Yang S, IFT20 governs mesenchymal stem cell fate through positively regulating TGF-beta-Smad2/3-Glut1 signaling mediated glucose metabolism. Redox Biol. 2022 Aug;54:102373 |
2 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:241849 Ma S, Santhosh D, Kumar T P, Huang Z, A Brain-Region-Specific Neural Pathway Regulating Germinal Matrix Angiogenesis. Dev Cell. 2017 May 22;41(4):366-381.e4 |
1 | J:237944 Mishra S, Choe Y, Pleasure SJ, Siegenthaler JA, Cerebrovascular defects in Foxc1 mutants correlate with aberrant WNT and VEGF-A pathways downstream of retinoic acid from the meninges. Dev Biol. 2016 Dec 01;420(1):148-165 |
1 | J:140565 Sakakura Y, Shibui T, Irie K, Yajima T, Metabolic mode peculiar to Meckel's cartilage: immunohistochemical comparisons of hypoxia-inducible factor-1alpha and glucose transporters in developing endochondral bones in mice. Eur J Oral Sci. 2008 Jul;116(4):341-52 |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
Slc2a2 solute carrier family 2 (facilitated glucose transporter), member 2 (Synonyms: Glut-2, Glut2, liver-type glucose transporter) | |
Results | Reference |
1 | J:105207 Chu K, Tsai MJ, Neuronatin, a downstream target of BETA2/NeuroD1 in the pancreas, is involved in glucose-mediated insulin secretion. Diabetes. 2005 Apr;54(4):1064-73 |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
1* | J:32017 Offield MF, Jetton TL, Labosky PA, Ray M, Stein RW, Magnuson MA, Hogan BL, Wright CV, PDX-1 is required for pancreatic outgrowth and differentiation of the rostral duodenum. Development. 1996 Mar;122(3):983-95 |
1 | J:225743 Um SH, Sticker-Jantscheff M, Chau GC, Vintersten K, Mueller M, Gangloff YG, Adams RH, Spetz JF, Elghazi L, Pfluger PT, Pende M, Bernal-Mizrachi E, Tauler A, Tschop MH, Thomas G, Kozma SC, S6K1 controls pancreatic beta cell size independently of intrauterine growth restriction. J Clin Invest. 2015 Jul 1;125(7):2736-47 |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
1 | J:144661 Zhang W, Feng D, Li Y, Iida K, McGrath B, Cavener DR, PERK EIF2AK3 control of pancreatic beta cell differentiation and proliferation is required for postnatal glucose homeostasis. Cell Metab. 2006 Dec;4(6):491-7 |
Slc2a3 solute carrier family 2 (facilitated glucose transporter), member 3 (Synonyms: Glut-3, Glut3) | |
Results | Reference |
1 | J:180242 Dupressoir A, Vernochet C, Harper F, Guegan J, Dessen P, Pierron G, Heidmann T, A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1164-73 |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
1 | J:121238 Ganguly A, McKnight RA, Raychaudhuri S, Shin BC, Ma Z, Moley K, Devaskar SU, Glucose transporter isoform-3 mutations cause early pregnancy loss and fetal growth restriction. Am J Physiol Endocrinol Metab. 2007 May;292(5):E1241-55 |
1 | J:140565 Sakakura Y, Shibui T, Irie K, Yajima T, Metabolic mode peculiar to Meckel's cartilage: immunohistochemical comparisons of hypoxia-inducible factor-1alpha and glucose transporters in developing endochondral bones in mice. Eur J Oral Sci. 2008 Jul;116(4):341-52 |
Slc2a4 solute carrier family 2 (facilitated glucose transporter), member 4 (Synonyms: Glut-4, Glut4, twgy) | |
Results | Reference |
1* | J:228878 Kosfeld A, Kreuzer M, Daniel C, Brand F, Schafer AK, Chadt A, Weiss AC, Riehmer V, Jeanpierre C, Klintschar M, Brasen JH, Amann K, Pape L, Kispert A, Al-Hasani H, Haffner D, Weber RG, Whole-exome sequencing identifies mutations of TBC1D1 encoding a Rab-GTPase-activating protein in patients with congenital anomalies of the kidneys and urinary tract (CAKUT). Hum Genet. 2016 Jan;135(1):69-87 |
Slc2a5 solute carrier family 2 (facilitated glucose transporter), member 5 (Synonyms: GLUT5) | |
Results | Reference |
1 | J:140565 Sakakura Y, Shibui T, Irie K, Yajima T, Metabolic mode peculiar to Meckel's cartilage: immunohistochemical comparisons of hypoxia-inducible factor-1alpha and glucose transporters in developing endochondral bones in mice. Eur J Oral Sci. 2008 Jul;116(4):341-52 |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
Slc2a9 solute carrier family 2 (facilitated glucose transporter), member 9 (Synonyms: Glut9, SLC2a9A, SLC2A9B) | |
Results | Reference |
1 | J:160518 Swartling FJ, Grimmer MR, Hackett CS, Northcott PA, Fan QW, Goldenberg DD, Lau J, Masic S, Nguyen K, Yakovenko S, Zhe XN, Gilmer HC, Collins R, Nagaoka M, Phillips JJ, Jenkins RB, Tihan T, Vandenberg SR, James CD, Tanaka K, Taylor MD, Weiss WA, Chesler L, Pleiotropic role for MYCN in medulloblastoma. Genes Dev. 2010 May 15;24(10):1059-72 |
Slc3a2 solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2 (Synonyms: 4F2HC, Cd98, Ly-10, Ly-m10, Mdu1, Mgp-2hc) | |
Results | Reference |
1 | J:342871 Xiang J, Pompetti AJ, Faranda AP, Wang Y, Novo SG, Li DW, Duncan MK, ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment. Cells. 2023 Nov 16;12(22) |
Slc4a1 solute carrier family 4 (anion exchanger), member 1 (Synonyms: Ae1, band 3, CD233, Empb3, erythrocyte membrane protein band 3, l11Jus51) | |
Results | Reference |
1 | J:355097 Gao C, Chen L, Chen E, Tsilosani A, Xia Y, Zhang W, Generation of Distal Renal Segments Involves a Unique Population of Aqp2 + Progenitor Cells. J Am Soc Nephrol. 2021 Dec 1;32(12):3035-3049 |
1* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
Slc4a9 solute carrier family 4, sodium bicarbonate cotransporter, member 9 (Synonyms: AE4, D630024F24Rik) | |
Results | Reference |
1 | J:249431 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ, Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6:e26851 |
Slc4a10 solute carrier family 4, sodium bicarbonate cotransporter-like, member 10 (Synonyms: NCBE) | |
Results | Reference |
1* | J:284778 Huebner AK, Maier H, Maul A, Nietzsche S, Herrmann T, Praetorius J, Hubner CA, Early Hearing Loss upon Disruption of Slc4a10 in C57BL/6 Mice. J Assoc Res Otolaryngol. 2019 Jun;20(3):233-245 |
Slc5a5 solute carrier family 5 (sodium iodide symporter), member 5 (Synonyms: NIS) | |
Results | Reference |
1* | J:171072 Carre A, Rachdi L, Tron E, Richard B, Castanet M, Schlumberger M, Bidart JM, Szinnai G, Polak M, Hes1 is required for appropriate morphogenesis and differentiation during mouse thyroid gland development. PLoS One. 2011;6(2):e16752 |
1 | J:352715 Kang HS, Grimm SA, Liao XH, Jetten AM, GLIS3 expression in the thyroid gland in relation to TSH signaling and regulation of gene expression. Cell Mol Life Sci. 2024 Jan 28;81(1):65 |
1 | J:80538 Postiglione MP, Parlato R, Rodriguez-Mallon A, Rosica A, Mithbaokar P, Maresca M, Marians RC, Davies TF, Zannini MS, De Felice M, Di Lauro R, Role of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15462-7 |
1 | J:169693 Silberschmidt D, Rodriguez-Mallon A, Mithboakar P, Cali G, Amendola E, Sanges R, Zannini M, Scarfo M, De Luca P, Nitsch L, Di Lauro R, De Felice M, In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1. BMC Dev Biol. 2011;11:9 |
Slc5a11 solute carrier family 5 (sodium/glucose cotransporter), member 11 (Synonyms: 2010013B02Rik, Kst1) | |
Results | Reference |
1 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
Slc6a1 solute carrier family 6 (neurotransmitter transporter, GABA), member 1 (Synonyms: Gabt, Gabt1, Gat1, GAT-1, XT-1, Xtrp1) | |
Results | Reference |
2* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Slc6a2 solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2 (Synonyms: NET, NE transporter, norepinephrine transporter, Slc6a5) | |
Results | Reference |
1 | J:166738 Li Z, Caron MG, Blakely RD, Margolis KG, Gershon MD, Dependence of serotonergic and other nonadrenergic enteric neurons on norepinephrine transporter expression. J Neurosci. 2010 Dec 8;30(49):16730-40 |
1* | J:286599 Song NN, Ma P, Zhang Q, Zhang L, Wang H, Zhang L, Zhu L, He CH, Mao B, Ding YQ, Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199 |
Slc6a3 solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 (Synonyms: DAT, Dat1) | |
Results | Reference |
1* | J:154889 Deschamps C, Faideau M, Jaber M, Gaillard A, Prestoz L, Expression of ephrinA5 during development and potential involvement in the guidance of the mesostriatal pathway. Exp Neurol. 2009 Oct;219(2):466-80 |
1 | J:161774 Wang S, Turner EE, Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity. J Neurosci. 2010 Jul 7;30(27):9224-7 |
Slc6a4 solute carrier family 6 (neurotransmitter transporter, serotonin), member 4 (Synonyms: 5-HTT, Htt, Sert) | |
Results | Reference |
2 | J:164404 Garcia-Frigola C, Herrera E, Zic2 regulates the expression of Sert to modulate eye-specific refinement at the visual targets. EMBO J. 2010 Sep 15;29(18):3170-83 |
1 | J:237535 Haugas M, Tikker L, Achim K, Salminen M, Partanen J, Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe. Development. 2016 Dec 01;143(23):4495-4508 |
1 | J:239986 Lahti L, Haugas M, Tikker L, Airavaara M, Voutilainen MH, Anttila J, Kumar S, Inkinen C, Salminen M, Partanen J, Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei. Development. 2016 Feb 01;143(3):516-29 |
2 | J:50802 Lebrand C, Cases O, Wehrle R, Blakely RD, Edwards RH, Gaspar P, Transient developmental expression of monoamine transporters in the rodent forebrain. J Comp Neurol. 1998 Nov 30;401(4):506-24 |
1 | J:75806 Pfaar H, von Holst A, Vogt Weisenhorn DM, Brodski C, Guimera J, Wurst W, mPet-1, a mouse ETS-domain transcription factor, is expressed in central serotonergic neurons. Dev Genes Evol. 2002 Feb;212(1):43-6 |
1 | J:123685 Saarimaki-Vire J, Peltopuro P, Lahti L, Naserke T, Blak AA, Vogt Weisenhorn DM, Yu K, Ornitz DM, Wurst W, Partanen J, Fibroblast growth factor receptors cooperate to regulate neural progenitor properties in the developing midbrain and hindbrain. J Neurosci. 2007 Aug 8;27(32):8581-92 |
1 | J:86868 Simon R, Lufkin T, Postnatal lethality in mice lacking the Sax2 homeobox gene homologous to Drosophila S59/slouch: evidence for positive and negative autoregulation. Mol Cell Biol. 2003 Dec;23(24):9046-60 |
1 | J:56671 Upton AL, Salichon N, Lebrand C, Ravary A, Blakely R, Seif I, Gaspar P, Excess of serotonin (5-HT) alters the segregation of ispilateral and contralateral retinal projections in monoamine oxidase A knock-out mice: possible role of 5-HT uptake in retinal ganglion cells during development. J Neurosci. 1999 Aug 15;19(16):7007-24 |
Slc6a5 solute carrier family 6 (neurotransmitter transporter, glycine), member 5 (Synonyms: Glyt2) | |
Results | Reference |
1 | J:104420 Glasgow SM, Henke RM, Macdonald RJ, Wright CV, Johnson JE, Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn. Development. 2005 Dec;132(24):5461-9 |
1 | J:142008 Huang M, Huang T, Xiang Y, Xie Z, Chen Y, Yan R, Xu J, Cheng L, Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons. Dev Biol. 2008 Jul 2;322(2):394-405 |
1 | J:34236 Jursky F, Nelson N, Developmental expression of the glycine transporters GLYT1 and GLYT2 in mouse brain. J Neurochem. 1996 Jul;67(1):336-44 |
Slc6a9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9 (Synonyms: Glyt-1, Glyt1) | |
Results | Reference |
1* | J:23734 Adams RH, Sato K, Shimada S, Tohyama M, Puschel AW, Betz H, Gene structure and glial expression of the glycine transporter GlyT1 in embryonic and adult rodents. J Neurosci. 1995 Mar;15(3 Pt 2):2524-32 |
1 | J:34236 Jursky F, Nelson N, Developmental expression of the glycine transporters GLYT1 and GLYT2 in mouse brain. J Neurochem. 1996 Jul;67(1):336-44 |
Slc6a11 solute carrier family 6 (neurotransmitter transporter, GABA), member 11 (Synonyms: D930045G19Rik, E130202I16Rik, Gabt4, Gat3, GAT4) | |
Results | Reference |
1* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Slc6a12 solute carrier family 6 (neurotransmitter transporter, betaine/GABA), member 12 (Synonyms: BGT1, Gabt2) | |
Results | Reference |
1* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Slc6a13 solute carrier family 6 (neurotransmitter transporter, GABA), member 13 (Synonyms: Gabt3, Gat2) | |
Results | Reference |
2* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
Slc7a1 solute carrier family 7 (cationic amino acid transporter, y+ system), member 1 (Synonyms: 4831426K01Rik, Atrc-1, Atrc1, Cat1, mCAT-1, Rec-1, Rev-1) | |
Results | Reference |
1 | J:117766 Chang J, Nicolas E, Marks D, Sander C, Lerro A, Buendia MA, Xu C, Mason WS, Moloshok T, Bort R, Zaret KS, Taylor JM, miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1. RNA Biol. 2004 Jul;1(2):106-13 |
Slc7a5 solute carrier family 7 (cationic amino acid transporter, y+ system), member 5 (Synonyms: D0H16S474E, Gm42049, LAT1, TA1) | |
Results | Reference |
1* | J:146910 Capelo LP, Beber EH, Fonseca TL, Gouveia CH, The monocarboxylate transporter 8 and L-type amino acid transporters 1 and 2 are expressed in mouse skeletons and in osteoblastic MC3T3-E1 cells. Thyroid. 2009 Feb;19(2):171-80 |
1 | J:335218 Knaus LS, Basilico B, Malzl D, Gerykova Bujalkova M, Smogavec M, Schwarz LA, Gorkiewicz S, Amberg N, Pauler FM, Knittl-Frank C, Tassinari M, Maulide N, Rulicke T, Menche J, Hippenmeyer S, Novarino G, Large neutral amino acid levels tune perinatal neuronal excitability and survival. Cell. 2023 Apr 27;186(9):1950-1967.e25 |
Slc7a8 solute carrier family 7 (cationic amino acid transporter, y+ system), member 8 (Synonyms: LAT2) | |
Results | Reference |
1* | J:59975 Bassi MT, Sperandeo MP, Incerti B, Bulfone A, Pepe A, Surace EM, Gattuso C, De Grandi A, Buoninconti A, Riboni M, Manzoni M, Andria G, Ballabio A, Borsani G, Sebastio G, SLC7A8, a gene mapping within the lysinuric protein intolerance critical region, encodes a new member of the glycoprotein-associated amino acid transporter family. Genomics. 1999 Dec 1;62(2):297-303 |
1* | J:146910 Capelo LP, Beber EH, Fonseca TL, Gouveia CH, The monocarboxylate transporter 8 and L-type amino acid transporters 1 and 2 are expressed in mouse skeletons and in osteoblastic MC3T3-E1 cells. Thyroid. 2009 Feb;19(2):171-80 |
Slc7a12 solute carrier family 7 (cationic amino acid transporter, y+ system), member 12 (Synonyms: Asc-2, asc-type amino acid transporter 2, XAT1) | |
Results | Reference |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
Slc8a1 solute carrier family 8 (sodium/calcium exchanger), member 1 (Synonyms: D930008O12Rik, Ncx1) | |
Results | Reference |
1* | J:81603 Conway SJ, Kruzynska-Frejtag A, Wang J, Rogers R, Kneer PL, Chen H, Creazzo T, Menick DR, Koushik SV, Role of sodium-calcium exchanger (Ncx1) in embryonic heart development: a transgenic rescue?. Ann N Y Acad Sci. 2002 Nov;976:268-81 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
2* | J:74176 Wakimoto K, Kuro-o M, Yanaka N, Komuro I, Nabeshima YI, Imai Y, Expression of Na+/Ca(2+) exchanger (NCX1) gene in the developmental mouse embryo and adult mouse brain. Comp Biochem Physiol B Biochem Mol Biol. 2001 Sep;130(2):191-8 |
Slc10a7 solute carrier family 10 (sodium/bile acid cotransporter family), member 7 (Synonyms: 2410193C02Rik) | |
Results | Reference |
1* | J:265027 Dubail J, Huber C, Chantepie S, Sonntag S, Tuysuz B, Mihci E, Gordon CT, Steichen-Gersdorf E, Amiel J, Nur B, Stolte-Dijkstra I, van Eerde AM, van Gassen KL, Breugem CC, Stegmann A, Lekszas C, Maroofian R, Karimiani EG, Bruneel A, Seta N, Munnich A, Papy-Garcia D, De La Dure-Molla M, Cormier-Daire V, SLC10A7 mutations cause a skeletal dysplasia with amelogenesis imperfecta mediated by GAG biosynthesis defects. Nat Commun. 2018 Aug 6;9(1):3087 |
1* | J:298768 Laugel-Haushalter V, Bar S, Schaefer E, Stoetzel C, Geoffroy V, Alembik Y, Kharouf N, Huckert M, Hamm P, Hemmerle J, Maniere MC, Friant S, Dollfus H, Bloch-Zupan A, A New SLC10A7 Homozygous Missense Mutation Responsible for a Milder Phenotype of Skeletal Dysplasia With Amelogenesis Imperfecta. Front Genet. 2019;10:504 |
Slc12a1 solute carrier family 12, member 1 (Synonyms: D630042G03Rik, mBSC1, Nkcc2, urehr3) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
2* | J:28941 Igarashi P, Vanden Heuvel GB, Payne JA, Forbush B 3rd, Cloning, embryonic expression, and alternative splicing of a murine kidney-specific Na-K-Cl cotransporter. Am J Physiol. 1995 Sep;269(3 Pt 2):F405-18 |
1 | J:353306 Ma YS, Deng SQ, Zhang P, Thomsen JS, Andreasen A, Chang SJ, Zhang J, Gu L, Zhai XY, Identification of countercurrent tubule-vessel arrangements in the early development of mouse kidney based on immunohistochemistry and computer-assisted 3D visualization. PLoS One. 2024;19(8):e0307223 |
1* | J:263032 Magella B, Mahoney R, Adam M, Potter SS, Reduced Abd-B Hox function during kidney development results in lineage infidelity. Dev Biol. 2018 Jun 15;438(2):84-93 |
1 | J:347984 Naillat F, Deshar G, Hankkila A, Rak-Raszewska A, Sharma A, Prunskaite-Hyyrylainen R, Railo A, Shan J, Vainio SJ, Calcium signaling induces partial EMT and renal fibrosis in a Wnt4(mCherry) knock-in mouse model. Biochim Biophys Acta Mol Basis Dis. 2024 Apr 21;1870(5):167180 |
1 | J:185279 Paces-Fessy M, Fabre M, Lesaulnier C, Cereghini S, Hnf1b and Pax2 cooperate to control different pathways in kidney and ureter morphogenesis. Hum Mol Genet. 2012 Jul 15;21(14):3143-55 |
1 | J:158678 Tran U, Zakin L, Schweickert A, Agrawal R, Doger R, Blum M, De Robertis EM, Wessely O, The RNA-binding protein bicaudal C regulates polycystin 2 in the kidney by antagonizing miR-17 activity. Development. 2010 Apr;137(7):1107-16 |
Slc12a2 solute carrier family 12, member 2 (Synonyms: mBSC2, Nkcc1, sodium/potassium/chloride cotransporters, sy-ns) | |
Results | Reference |
1 | J:103002 Ando Z, Sato S, Ikeda K, Kawakami K, Slc12a2 is a direct target of two closely related homeobox proteins, Six1 and Six4. FEBS J. 2005 Jun;272(12):3026-41 |
1 | J:347984 Naillat F, Deshar G, Hankkila A, Rak-Raszewska A, Sharma A, Prunskaite-Hyyrylainen R, Railo A, Shan J, Vainio SJ, Calcium signaling induces partial EMT and renal fibrosis in a Wnt4(mCherry) knock-in mouse model. Biochim Biophys Acta Mol Basis Dis. 2024 Apr 21;1870(5):167180 |
1 | J:356070 Song EC, Min S, Oyelakin A, Smalley K, Bard JE, Liao L, Xu J, Romano RA, Genetic and scRNA-seq Analysis Reveals Distinct Cell Populations that Contribute to Salivary Gland Development and Maintenance. Sci Rep. 2018 Sep 19;8(1):14043 |
2* | J:112319 Vanden Heuvel GB, Payne JA, Igarashi P, Forbush B rd, Expression of the basolateral Na-K-Cl cotransporter during mouse nephrogenesis and embryonic development. Gene Expr Patterns. 2006 Dec;6(8):1000-6 |
Slc12a3 solute carrier family 12, member 3 (Synonyms: NCC, TSC) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
1 | J:185279 Paces-Fessy M, Fabre M, Lesaulnier C, Cereghini S, Hnf1b and Pax2 cooperate to control different pathways in kidney and ureter morphogenesis. Hum Mol Genet. 2012 Jul 15;21(14):3143-55 |
1 | J:180153 Veikkolainen V, Naillat F, Railo A, Chi L, Manninen A, Hohenstein P, Hastie N, Vainio S, Elenius K, ErbB4 Modulates Tubular Cell Polarity and Lumen Diameter during Kidney Development. J Am Soc Nephrol. 2012 Jan;23(1):112-22 |
1 | J:291675 Zhang P, Gu L, Cong J, Zhang J, Thomsen JS, Andreasen A, Chang SJ, Deng SQ, Xing J, Zhai XY, Morphology of the initial nephron-collecting duct connection in mice using computerized 3D tracing and electron microscopy. Biochem Biophys Res Commun. 2019 Jan 29;509(1):114-118 |
Slc12a5 solute carrier family 12, member 5 (Synonyms: KCC2, mKIAA1176) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1 | J:87826 Stein V, Hermans-Borgmeyer I, Jentsch TJ, Hubner CA, Expression of the KCl cotransporter KCC2 parallels neuronal maturation and the emergence of low intracellular chloride. J Comp Neurol. 2004 Jan 1;468(1):57-64 |
Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 (Synonyms: MCT1) | |
Results | Reference |
1 | J:333799 Radford BN, Zhao X, Glazer T, Eaton M, Blackwell D, Mohammad S, Lo Vercio LD, Devine J, Shalom-Barak T, Hallgrimsson B, Cross JC, Sucov HM, Barak Y, Dean W, Hemberger M, Defects in placental syncytiotrophoblast cells are a common cause of developmental heart disease. Nat Commun. 2023 Mar 1;14(1):1174 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Slc16a2 solute carrier family 16 (monocarboxylic acid transporters), member 2 (Synonyms: MCT8, XPCT) | |
Results | Reference |
1* | J:146910 Capelo LP, Beber EH, Fonseca TL, Gouveia CH, The monocarboxylate transporter 8 and L-type amino acid transporters 1 and 2 are expressed in mouse skeletons and in osteoblastic MC3T3-E1 cells. Thyroid. 2009 Feb;19(2):171-80 |
1 | J:357738 Liu Y, Ng L, Liu H, Heuer H, Forrest D, Cone photoreceptor differentiation regulated by thyroid hormone transporter MCT8 in the retinal pigment epithelium. Proc Natl Acad Sci U S A. 2024 Jul 23;121(30):e2402560121 |
Slc16a3 solute carrier family 16 (monocarboxylic acid transporters), member 3 (Synonyms: MCT3, MCT4, monocarboxylate transporter 4) | |
Results | Reference |
1 | J:286013 Outhwaite JE, Patel J, Simmons DG, Secondary Placental Defects in Cxadr Mutant Mice. Front Physiol. 2019;10:622 |
1 | J:333799 Radford BN, Zhao X, Glazer T, Eaton M, Blackwell D, Mohammad S, Lo Vercio LD, Devine J, Shalom-Barak T, Hallgrimsson B, Cross JC, Sucov HM, Barak Y, Dean W, Hemberger M, Defects in placental syncytiotrophoblast cells are a common cause of developmental heart disease. Nat Commun. 2023 Mar 1;14(1):1174 |
Slc16a7 solute carrier family 16 (monocarboxylic acid transporters), member 7 (Synonyms: 4921534N07Rik, 9030411M13Rik, D630004K10Rik, MCT2) | |
Results | Reference |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
Slc17a5 solute carrier family 17 (anion/sugar transporter), member 5 (Synonyms: 4631416G20Rik) | |
Results | Reference |
1* | J:99712 Yarovaya N, Schot R, Fodero L, McMahon M, Mahoney A, Williams R, Verbeek E, de Bondt A, Hampson M, van der Spek P, Stubbs A, Masters CL, Verheijen FW, Mancini GM, Venter DJ, Sialin, an anion transporter defective in sialic acid storage diseases, shows highly variable expression in adult mouse brain, and is developmentally regulated. Neurobiol Dis. 2005 Aug;19(3):351-65 |
Slc17a6 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 6 (Synonyms: 2900073D12Rik, VGLUT2) | |
Results | Reference |
1 | J:156468 Birgner C, Nordenankar K, Lundblad M, Mendez JA, Smith C, le Greves M, Galter D, Olson L, Fredriksson A, Trudeau LE, Kullander K, Wallen-Mackenzie A, VGLUT2 in dopamine neurons is required for psychostimulant-induced behavioral activation. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):389-94 |
2 | J:104420 Glasgow SM, Henke RM, Macdonald RJ, Wright CV, Johnson JE, Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn. Development. 2005 Dec;132(24):5461-9 |
1* | J:136732 Guirado S, Real MA, Davila JC, Distinct immunohistochemically defined areas in the medial amygdala in the developing and adult mouse. Brain Res Bull. 2008 Mar 18;75(2-4):214-7 |
1 | J:130251 Hori K, Cholewa-Waclaw J, Nakada Y, Glasgow SM, Masui T, Henke RM, Wildner H, Martarelli B, Beres TM, Epstein JA, Magnuson MA, Macdonald RJ, Birchmeier C, Johnson JE, A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes Dev. 2008 Jan 15;22(2):166-78 |
1 | J:170540 Jeong Y, Dolson DK, Waclaw RR, Matise MP, Sussel L, Campbell K, Kaestner KH, Epstein DJ, Spatial and temporal requirements for sonic hedgehog in the regulation of thalamic interneuron identity. Development. 2011 Feb;138(3):531-41 |
1* | J:195909 Lam RS, Mombaerts P, Odorant responsiveness of embryonic mouse olfactory sensory neurons expressing the odorant receptors S1 or MOR23. Eur J Neurosci. 2013 Jul;38(2):2210-7 |
1 | J:244498 Lee B, Lee M, Song S, Loi LD, Lam DT, Yoon J, Baek K, Curtis DJ, Jeong Y, Specification of neurotransmitter identity by Tal1 in thalamic nuclei. Dev Dyn. 2017 Oct;246(10):749-758 |
1 | J:254523 Magno L, Barry C, Schmidt-Hieber C, Theodotou P, Hausser M, Kessaris N, NKX2-1 Is Required in the Embryonic Septum for Cholinergic System Development, Learning, and Memory. Cell Rep. 2017 Aug 15;20(7):1572-1584 |
1 | J:258875 Mona B, Uruena A, Kollipara RK, Ma Z, Borromeo MD, Chang JC, Johnson JE, Repression by PRDM13 is critical for generating precision in neuronal identity. Elife. 2017 Aug 29;6:e25787 |
1 | J:331478 Monko T, Rebertus J, Stolley J, Salton SR, Nakagawa Y, Thalamocortical axons regulate neurogenesis and laminar fates in the early sensory cortex. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2201355119 |
1 | J:162166 Peltopuro P, Kala K, Partanen J, Distinct requirements for Ascl1 in subpopulations of midbrain GABAergic neurons. Dev Biol. 2010 Jul 1;343(1-2):63-70 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:345248 Tran HN, Nguyen QH, Jeong Y, Dbx1 is a dorsal midbrain-specific determinant of GABAergic neuron fate and regulates differentiation of the dorsal midbrain into the inferior and superior colliculi. Front Cell Dev Biol. 2024;12:1336308 |
1* | J:287411 Tran HN, Park W, Seong S, Jeong JE, Nguyen QH, Yoon J, Baek K, Jeong Y, Tcf7l2 transcription factor is required for the maintenance, but not the initial specification, of the neurotransmitter identity in the caudal thalamus. Dev Dyn. 2020 May;249(5):646-655 |
1 | J:181187 Woo SH, Baba Y, Franco AM, Lumpkin EA, Owens DM, Excitatory glutamate is essential for development and maintenance of the piloneural mechanoreceptor. Development. 2012 Feb;139(4):740-8 |
1 | J:201733 Xu Y, Lopes C, Wende H, Guo Z, Cheng L, Birchmeier C, Ma Q, Ontogeny of excitatory spinal neurons processing distinct somatic sensory modalities. J Neurosci. 2013 Sep 11;33(37):14738-48 |
Slc17a7 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7 (Synonyms: 2900052E22Rik, Vglut1) | |
Results | Reference |
1 | J:161851 Honma Y, Kawano M, Kohsaka S, Ogawa M, Axonal projections of mechanoreceptive dorsal root ganglion neurons depend on Ret. Development. 2010 Jul;137(14):2319-28 |
1 | J:151894 Oishi K, Watatani K, Itoh Y, Okano H, Guillemot F, Nakajima K, Gotoh Y, Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):13064-9 |
Slc17a8 solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8 (Synonyms: Vglut3, Vgt3) | |
Results | Reference |
1 | J:237535 Haugas M, Tikker L, Achim K, Salminen M, Partanen J, Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe. Development. 2016 Dec 01;143(23):4495-4508 |
1* | J:282727 Li C, Shu Y, Wang G, Zhang H, Lu Y, Li X, Li G, Song L, Liu Z, Characterizing a novel vGlut3-P2A-iCreER knockin mouse strain in cochlea. Hear Res. 2018 Jul;364:12-24 |
Slc18a1 solute carrier family 18 (vesicular monoamine), member 1 (Synonyms: 4832416I10Rik, MGC:28683, MGC:37299) | |
Results | Reference |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
Slc18a2 solute carrier family 18 (vesicular monoamine), member 2 (Synonyms: 1110037L13Rik, Vmat2) | |
Results | Reference |
2 | J:50802 Lebrand C, Cases O, Wehrle R, Blakely RD, Edwards RH, Gaspar P, Transient developmental expression of monoamine transporters in the rodent forebrain. J Comp Neurol. 1998 Nov 30;401(4):506-24 |
1 | J:161774 Wang S, Turner EE, Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity. J Neurosci. 2010 Jul 7;30(27):9224-7 |
Slc18a3 solute carrier family 18 (vesicular monoamine), member 3 (Synonyms: VAChT, VAT) | |
Results | Reference |
1* | J:321845 Bernhardt N, Memic F, Velica A, Tran MA, Vieillard J, Sayyab S, Chersa T, Andersson L, Whelan PJ, Boije H, Kullander K, Hop Mice Display Synchronous Hindlimb Locomotion and a Ventrally Fused Lumbar Spinal Cord Caused by a Point Mutation in Ttc26. eNeuro. 2022 Mar-Apr;9(2):ENEURO.0518-21.2022 |
1 | J:92351 Burau K, Stenull I, Huber K, Misawa H, Berse B, Unsicker K, Ernsberger U, c-ret regulates cholinergic properties in mouse sympathetic neurons: evidence from mutant mice. Eur J Neurosci. 2004 Jul;20(2):353-62 |
1 | J:213234 Cho HH, Cargnin F, Kim Y, Lee B, Kwon RJ, Nam H, Shen R, Barnes AP, Lee JW, Lee S, Lee SK, Isl1 directly controls a cholinergic neuronal identity in the developing forebrain and spinal cord by forming cell type-specific complexes. PLoS Genet. 2014 Apr;10(4):e1004280 |
1 | J:166770 Coppola E, d'Autreaux F, Rijli FM, Brunet JF, Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation. Development. 2010 Dec;137(24):4211-20 |
1 | J:237201 Espinosa-Medina I, Saha O, Boismoreau F, Chettouh Z, Rossi F, Richardson WD, Brunet JF, The sacral autonomic outflow is sympathetic. Science. 2016 Nov 18;354(6314):893-897 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1 | J:306265 Hao MM, Fung C, Boesmans W, Lowette K, Tack J, Vanden Berghe P, Development of the intrinsic innervation of the small bowel mucosa and villi. Am J Physiol Gastrointest Liver Physiol. 2020 Jan 1;318(1):G53-G65 |
1 | J:345795 Hsu HC, Hsu SP, Hsu FY, Chang M, Chen JA, LncRNA Litchi is a regulator for harmonizing maturity and resilient functionality in spinal motor neurons. iScience. 2024 Mar 15;27(3):109207 |
1 | J:199638 Huang T, Hu J, Wang B, Nie Y, Geng J, Cheng L, Tlx3 controls cholinergic transmitter and Peptide phenotypes in a subset of prenatal sympathetic neurons. J Neurosci. 2013 Jun 26;33(26):10667-75 |
1* | J:42766 Sang Q, Young HM, Development of nicotinic receptor clusters and innervation accompanying the change in muscle phenotype in the mouse esophagus. J Comp Neurol. 1997 Sep 15;386(1):119-36 |
1 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
1 | J:277336 Turco AE, Cadena MT, Zhang HL, Sandhu JK, Oakes SR, Chathurvedula T, Peterson RE, Keast JR, Vezina CM, A temporal and spatial map of axons in developing mouse prostate. Histochem Cell Biol. 2019 Jul;152(1):35-45 |
1 | J:60159 Wolpowitz D, Mason TB, Dietrich P, Mendelsohn M, Talmage DA, Role LW, Cysteine-rich domain isoforms of the neuregulin-1 gene are required for maintenance of peripheral synapses. Neuron. 2000 Jan;25(1):79-91 |
Slc20a1 solute carrier family 20, member 1 (Synonyms: Glvr-1, Glvr1, PiT-1) | |
Results | Reference |
1* | J:257428 Merametdjian L, Beck-Cormier S, Bon N, Couasnay G, Sourice S, Guicheux J, Gaucher C, Beck L, Expression of Phosphate Transporters during Dental Mineralization. J Dent Res. 2018 Feb;97(2):209-217 |
Slc20a2 solute carrier family 20, member 2 (Synonyms: MolPit2, Pit-2, PiT-2, Ram-1, Ram1) | |
Results | Reference |
1* | J:257428 Merametdjian L, Beck-Cormier S, Bon N, Couasnay G, Sourice S, Guicheux J, Gaucher C, Beck L, Expression of Phosphate Transporters during Dental Mineralization. J Dent Res. 2018 Feb;97(2):209-217 |
Slc22a1 solute carrier family 22 (organic cation transporter), member 1 (Synonyms: Lx1, MGC:14019, Oct1, Oct1, Orct, Orct1) | |
Results | Reference |
1 | J:330742 Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM, In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022 Oct 17;132(20):e156955 |
1 | J:61599 Pavlova A, Sakurai H, Leclercq B, Beier DR, Yu AS, Nigam SK, Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct. Am J Physiol Renal Physiol. 2000 Apr;278(4):F635-43 |
Slc22a2 solute carrier family 22 (organic cation transporter), member 2 (Synonyms: MGC:18339, Oct2, Orct2) | |
Results | Reference |
1 | J:173801 Hudson QJ, Seidl CI, Kulinski TM, Huang R, Warczok KE, Bittner R, Bartolomei MS, Barlow DP, Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo. Dev Biol. 2011 May 15;353(2):420-31 |
Slc22a3 solute carrier family 22 (organic cation transporter), member 3 (Synonyms: EMT, Oct3, Orct3) | |
Results | Reference |
1 | J:173801 Hudson QJ, Seidl CI, Kulinski TM, Huang R, Warczok KE, Bittner R, Bartolomei MS, Barlow DP, Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo. Dev Biol. 2011 May 15;353(2):420-31 |
1* | J:52875 Verhaagh S, Schweifer N, Barlow DP, Zwart R, Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27. Genomics. 1999 Jan 15;55(2):209-18 |
Slc22a6 solute carrier family 22 (organic anion transporter), member 6 (Synonyms: mOat1, NKT, Oat1, Orctl1) | |
Results | Reference |
1* | J:151683 Parreira KS, Debaix H, Cnops Y, Geffers L, Devuyst O, Expression patterns of the aquaporin gene family during renal development: influence of genetic variability. Pflugers Arch. 2009 Aug;458(4):745-59 |
2 | J:61599 Pavlova A, Sakurai H, Leclercq B, Beier DR, Yu AS, Nigam SK, Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct. Am J Physiol Renal Physiol. 2000 Apr;278(4):F635-43 |
Slc22a8 solute carrier family 22 (organic anion transporter), member 8 (Synonyms: mOat3, OAT3, Roct) | |
Results | Reference |
1 | J:61599 Pavlova A, Sakurai H, Leclercq B, Beier DR, Yu AS, Nigam SK, Developmentally regulated expression of organic ion transporters NKT (OAT1), OCT1, NLT (OAT2), and Roct. Am J Physiol Renal Physiol. 2000 Apr;278(4):F635-43 |
Slc22a18 solute carrier family 22 (organic cation transporter), member 18 (Synonyms: BWR1A, BWSCR1A, Impt1, IMPT1, Orctl2, p45-BWR1A, Slc22a1l, TSSC5) | |
Results | Reference |
1 | J:79882 Fitzpatrick GV, Soloway PD, Higgins MJ, Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1. Nat Genet. 2002 Nov;32(3):426-31 |
1 | J:93878 Salas M, John R, Saxena A, Barton S, Frank D, Fitzpatrick G, Higgins MJ, Tycko B, Placental growth retardation due to loss of imprinting of Phlda2. Mech Dev. 2004 Oct;121(10):1199-210 |
Slc23a2 solute carrier family 23 (nucleobase transporters), member 2 (Synonyms: mKIAA0238, Slc23a1, SVCT2, YSPL3) | |
Results | Reference |
1 | J:338914 Cao B, Xia Y, Cai Z, Wang Z, Tang C, Song Y, Construction of a Brain-specific SLC23A2 Gene Knockout Mice Model. Neuroscience. 2023 Aug 1;524:137-148 |
Slc24a4 solute carrier family 24 (sodium/potassium/calcium exchanger), member 4 (Synonyms: A930002M03Rik, NCKX4) | |
Results | Reference |
1* | J:306594 De Maria A, Zhao H, Bassnett S, Expression of potassium-dependent sodium-calcium exchanger in the murine lens. Exp Eye Res. 2018 Feb;167:18-24 |
Slc25a3 solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3 (Synonyms: 5730556H19Rik, Phc) | |
Results | Reference |
1* | J:259125 Yang J, Hung LH, Licht T, Kostin S, Looso M, Khrameeva E, Bindereif A, Schneider A, Braun T, RBM24 is a major regulator of muscle-specific alternative splicing. Dev Cell. 2014 Oct 13;31(1):87-99 |
Slc25a5 solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5 (Synonyms: adenine nucleotide translocase, Ant2) | |
Results | Reference |
1* | J:286886 Lim CH, Brower JV, Resnick JL, Oh SP, Terada N, Adenine nucleotide translocase 4 is expressed within embryonic ovaries and dispensable during oogenesis. Reprod Sci. 2015 Feb;22(2):250-7 |
Slc25a31 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31 (Synonyms: 1700034J06Rik) | |
Results | Reference |
1* | J:286886 Lim CH, Brower JV, Resnick JL, Oh SP, Terada N, Adenine nucleotide translocase 4 is expressed within embryonic ovaries and dispensable during oogenesis. Reprod Sci. 2015 Feb;22(2):250-7 |
Slc26a4 solute carrier family 26, member 4 (Synonyms: Pds, pendrin) | |
Results | Reference |
1 | J:215675 Deng M, Luo XJ, Pan L, Yang H, Xie X, Liang G, Huang L, Hu F, Kiernan AE, Gan L, LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea. J Neurosci. 2014 Jul 23;34(30):10072-7 |
1* | J:360528 Fritzsch B, Weng X, Yamoah EN, Qin T, Hui CC, Lebron-Mora L, Pavlinkova G, Sham MH, Irx3/5 Null Deletion in Mice Blocks Cochlea-Saccule Segregation and Disrupts the Auditory Tonotopic Map. J Comp Neurol. 2024 Dec;532(12):e70008 |
1 | J:355097 Gao C, Chen L, Chen E, Tsilosani A, Xia Y, Zhang W, Generation of Distal Renal Segments Involves a Unique Population of Aqp2 + Progenitor Cells. J Am Soc Nephrol. 2021 Dec 1;32(12):3035-3049 |
1 | J:249431 Honda K, Kim SH, Kelly MC, Burns JC, Constance L, Li X, Zhou F, Hoa M, Kelley MW, Wangemann P, Morell RJ, Griffith AJ, Molecular architecture underlying fluid absorption by the developing inner ear. Elife. 2017 Oct 10;6:e26851 |
1 | J:82307 Hulander M, Kiernan AE, Blomqvist SR, Carlsson P, Samuelsson EJ, Johansson BR, Steel KP, Enerback S, Lack of pendrin expression leads to deafness and expansion of the endolymphatic compartment in inner ears of Foxi1 null mutant mice. Development. 2003 May;130(9):2013-25 |
1* | J:150394 Jouret F, Auzanneau C, Debaix H, Wada GH, Pretto C, Marbaix E, Karet FE, Courtoy PJ, Devuyst O, Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis. J Am Soc Nephrol. 2005 Nov;16(11):3235-46 |
1 | J:171693 Kim HM, Wangemann P, Epithelial cell stretching and luminal acidification lead to a retarded development of stria vascularis and deafness in mice lacking pendrin. PLoS One. 2011;6(3):e17949 |
2 | J:285979 Kim MA, Kim SH, Ryu N, Ma JH, Kim YR, Jung J, Hsu CJ, Choi JY, Lee KY, Wangemann P, Bok J, Kim UK, Gene therapy for hereditary hearing loss by SLC26A4 mutations in mice reveals distinct functional roles of pendrin in normal hearing. Theranostics. 2019;9(24):7184-7199 |
1 | J:199292 Li X, Sanneman JD, Harbidge DG, Zhou F, Ito T, Nelson R, Picard N, Chambrey R, Eladari D, Miesner T, Griffith AJ, Marcus DC, Wangemann P, SLC26A4 Targeted to the Endolymphatic Sac Rescues Hearing and Balance in Slc26a4 Mutant Mice. PLoS Genet. 2013 Jul;9(7):e1003641 |
Slc27a4 solute carrier family 27 (fatty acid transporter), member 4 (Synonyms: FATP4, fatty acid transport protein 4) | |
Results | Reference |
1* | J:244468 Lin MH, Hsu FF, Miner JH, Requirement of fatty acid transport protein 4 for development, maturation, and function of sebaceous glands in a mouse model of ichthyosis prematurity syndrome. J Biol Chem. 2013 Feb 08;288(6):3964-76 |
Slc30a3 solute carrier family 30 (zinc transporter), member 3 (Synonyms: Znt3) | |
Results | Reference |
1* | J:80104 Valente T, Auladell C, Developmental expression of ZnT3 in mouse brain: correlation between the vesicular zinc transporter protein and chelatable vesicular zinc (CVZ) cells. Glial and neuronal CVZ cells interact. Mol Cell Neurosci. 2002 Oct;21(2):189-204 |
Slc31a1 solute carrier family 31, member 1 (Synonyms: 4930445G01Rik, Ctr1) | |
Results | Reference |
1* | J:69862 Kuo YM, Zhou B, Cosco D, Gitschier J, The copper transporter CTR1 provides an essential function in mammalian embryonic development. Proc Natl Acad Sci U S A. 2001 Jun 5;98(12):6836-41 |
Slc32a1 solute carrier family 32 (GABA vesicular transporter), member 1 (Synonyms: R75019, VGAT, Viaat) | |
Results | Reference |
1 | J:90585 Cheng L, Arata A, Mizuguchi R, Qian Y, Karunaratne A, Gray PA, Arata S, Shirasawa S, Bouchard M, Luo P, Chen CL, Busslinger M, Goulding M, Onimaru H, Ma Q, Tlx3 and Tlx1 are post-mitotic selector genes determining glutamatergic over GABAergic cell fates. Nat Neurosci. 2004 May;7(5):510-7 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
2* | J:143211 Kwakowsky A, Schwirtlich M, Kooy F, Abraham I, Mate Z, Katarova Z, Szabo G, GABA neurotransmitter signaling in the developing mouse lens: dynamic regulation of components and functionality. Dev Dyn. 2008 Dec;237(12):3830-41 |
1* | J:158888 Oh WJ, Westmoreland JJ, Summers R, Condie BG, Cleft palate is caused by CNS dysfunction in Gad1 and Viaat knockout mice. PLoS One. 2010;5(3):e9758 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
Slc33a1 solute carrier family 33 (acetyl-CoA transporter), member 1 (Synonyms: Acatn, D630022N01Rik) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Slc34a1 solute carrier family 34 (sodium phosphate), member 1 (Synonyms: Na/Pi cotransporter, NaPi-IIa, Npt2, renal Na+/Pi transporter, Slc17a2) | |
Results | Reference |
2* | J:111272 Chau H, El-Maadawy S, McKee MD, Tenenhouse HS, Renal calcification in mice homozygous for the disrupted type IIa Na/Pi cotransporter gene Npt2. J Bone Miner Res. 2003 Apr;18(4):644-57 |
1 | J:347984 Naillat F, Deshar G, Hankkila A, Rak-Raszewska A, Sharma A, Prunskaite-Hyyrylainen R, Railo A, Shan J, Vainio SJ, Calcium signaling induces partial EMT and renal fibrosis in a Wnt4(mCherry) knock-in mouse model. Biochim Biophys Acta Mol Basis Dis. 2024 Apr 21;1870(5):167180 |
1* | J:151683 Parreira KS, Debaix H, Cnops Y, Geffers L, Devuyst O, Expression patterns of the aquaporin gene family during renal development: influence of genetic variability. Pflugers Arch. 2009 Aug;458(4):745-59 |
Slc34a2 solute carrier family 34 (sodium phosphate), member 2 (Synonyms: D5Ertd227e, NaPi-2b, Npt2b, type IIb Na/Picotransporter) | |
Results | Reference |
1* | J:257428 Merametdjian L, Beck-Cormier S, Bon N, Couasnay G, Sourice S, Guicheux J, Gaucher C, Beck L, Expression of Phosphate Transporters during Dental Mineralization. J Dent Res. 2018 Feb;97(2):209-217 |
1 | J:190056 Xu Y, Wang Y, Besnard V, Ikegami M, Wert SE, Heffner C, Murray SA, Donahue LR, Whitsett JA, Transcriptional programs controlling perinatal lung maturation. PLoS One. 2012;7(8):e37046 |
Slc38a1 solute carrier family 38, member 1 (Synonyms: NAT2, SNAT1) | |
Results | Reference |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
Slc38a2 solute carrier family 38, member 2 (Synonyms: 5033402L14Rik, mKIAA1382, SNAT2) | |
Results | Reference |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
Slc38a4 solute carrier family 38, member 4 (Synonyms: 1110012E16Rik, 1700012A18Rik, Ata3) | |
Results | Reference |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
Slc39a8 solute carrier family 39 (metal ion transporter), member 8 (Synonyms: 4933419D20Rik, BIGM103, ZIP8) | |
Results | Reference |
2* | J:278469 Galvez-Peralta M, He L, Jorge-Nebert LF, Wang B, Miller ML, Eppert BL, Afton S, Nebert DW, ZIP8 zinc transporter: indispensable role for both multiple-organ organogenesis and hematopoiesis in utero. PLoS One. 2012;7(5):e36055 |
2* | J:174970 Wang B, He L, Dong H, Dalton TP, Nebert DW, Generation of a Slc39a8 hypomorph mouse: markedly decreased ZIP8 Zn(2)/(HCO) transporter expression. Biochem Biophys Res Commun. 2011 Jul 1;410(2):289-94 |
Slc39a14 solute carrier family 39 (zinc transporter), member 14 (Synonyms: G630015O18Rik, MGC:38539, Zip14) | |
Results | Reference |
1 | J:171670 Hojyo S, Fukada T, Shimoda S, Ohashi W, Bin BH, Koseki H, Hirano T, The zinc transporter SLC39A14/ZIP14 controls G-protein coupled receptor-mediated signaling required for systemic growth. PLoS One. 2011;6(3):e18059 |
Slc40a1 solute carrier family 40 (iron-regulated transporter), member 1 (Synonyms: Dusg, ferroportin1, FPN1, IREG1, metal transporting protein 1, MTP1, Ol5, Pcm, Slc11a3) | |
Results | Reference |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
2 | J:98335 Mok H, Mendoza M, Prchal JT, Balogh P, Schumacher A, Dysregulation of ferroportin 1 interferes with spleen organogenesis in polycythaemia mice. Development. 2004 Oct;131(19):4871-81 |
Slc43a3 solute carrier family 43, member 3 (Synonyms: Eeg1, SEEEG-1) | |
Results | Reference |
1* | J:74194 Stuart RO, Pavlova A, Beier D, Li Z, Krijanovski Y, Nigam SK, EEG1, a putative transporter expressed during epithelial organogenesis: comparison with embryonic transporter expression during nephrogenesis. Am J Physiol Renal Physiol. 2001 Dec;281(6):F1148-56 |
Slc45a4 solute carrier family 45, member 4 (Synonyms: 9330175B01Rik) | |
Results | Reference |
1* | J:288134 Suenkel C, Cavalli D, Massalini S, Calegari F, Rajewsky N, A Highly Conserved Circular RNA Is Required to Keep Neural Cells in a Progenitor State in the Mammalian Brain. Cell Rep. 2020 Feb 18;30(7):2170-2179.e5 |
Slc52a3 solute carrier protein family 52, member 3 (Synonyms: 2310046K01Rik) | |
Results | Reference |
1* | J:298819 Jin C, Yonezawa A, Yoshimatsu H, Imai S, Koyanagi M, Yamanishi K, Nakagawa S, Itohara K, Omura T, Nakagawa T, Nagai J, Matsubara K, Effect of riboflavin deficiency on development of the cerebral cortex in Slc52a3 knockout mice. Sci Rep. 2020 Oct 28;10(1):18443 |
Slco1c1 solute carrier organic anion transporter family, member 1c1 (Synonyms: OATP-F, Slc21a14) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Slit1 slit guidance ligand 1 (Synonyms: mKIAA0813, Slil1) | |
Results | Reference |
1 | J:195145 Amaniti EM, Hasenpusch-Theil K, Li Z, Magnani D, Kessaris N, Mason JO, Theil T, Gli3 is required in Emx1(+) progenitors for the development of the corpus callosum. Dev Biol. 2013 Apr 15;376(2):113-24 |
1 | J:315765 Borrell V, Cardenas A, Ciceri G, Galceran J, Flames N, Pla R, Nobrega-Pereira S, Garcia-Frigola C, Peregrin S, Zhao Z, Ma L, Tessier-Lavigne M, Marin O, Slit/Robo signaling modulates the proliferation of central nervous system progenitors. Neuron. 2012 Oct 18;76(2):338-52 |
1 | J:264379 Cardenas A, Villalba A, de Juan Romero C, Pico E, Kyrousi C, Tzika AC, Tessier-Lavigne M, Ma L, Drukker M, Cappello S, Borrell V, Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels. Cell. 2018 Jul 26;174(3):590-606.e21 |
1* | J:71421 Loes S, Luukko K, Kvinnsland IH, Kettunen P, Slit1 is specifically expressed in the primary and secondary enamel knots during molar tooth cusp formation. Mech Dev. 2001 Sep;107(1-2):155-7 |
1* | J:134543 Nguyen-Ba-Charvet KT, Di Meglio T, Fouquet C, Chedotal A, Robos and slits control the pathfinding and targeting of mouse olfactory sensory axons. J Neurosci. 2008 Apr 16;28(16):4244-9 |
1 | J:154741 Prince JE, Cho JH, Dumontier E, Andrews W, Cutforth T, Tessier-Lavigne M, Parnavelas J, Cloutier JF, Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. J Neurosci. 2009 Nov 11;29(45):14211-22 |
1 | J:119315 Thompson H, Barker D, Camand O, Erskine L, Slits contribute to the guidance of retinal ganglion cell axons in the mammalian optic tract. Dev Biol. 2006 Aug 15;296(2):476-84 |
1* | J:184936 Unni DK, Piper M, Moldrich RX, Gobius I, Liu S, Fothergill T, Donahoo AL, Baisden JM, Cooper HM, Richards LJ, Multiple Slits regulate the development of midline glial populations and the corpus callosum. Dev Biol. 2012 May 1;365(1):36-49 |
2 | J:199796 Wang SZ, Ibrahim LA, Kim YJ, Gibson DA, Leung HC, Yuan W, Zhang KK, Tao HW, Ma L, Zhang LI, Slit/Robo Signaling Mediates Spatial Positioning of Spiral Ganglion Neurons during Development of Cochlear Innervation. J Neurosci. 2013 Jul 24;33(30):12242-54 |
1 | J:282590 Wei S, Du H, Li Z, Tao G, Xu Z, Song X, Shang Z, Su Z, Chen H, Wen Y, Liu G, You Y, Zhang Z, Yang Z, Transcription factors Sp8 and Sp9 regulate the development of caudal ganglionic eminence-derived cortical interneurons. J Comp Neurol. 2019 Dec 1;527(17):2860-2874 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
1 | J:223471 Zhao X, Chen Y, Zhu Q, Huang H, Teng P, Zheng K, Hu X, Xie B, Zhang Z, Sander M, Qiu M, Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor. PLoS One. 2014;9(10):e109171 |
1 | J:161800 Zheng K, Li H, Zhu Y, Zhu Q, Qiu M, MicroRNAs are essential for the developmental switch from neurogenesis to gliogenesis in the developing spinal cord. J Neurosci. 2010 Jun 16;30(24):8245-50 |
Slit2 slit guidance ligand 2 (Synonyms: b2b1200.1Clo, Drad-1, E030015M03Rik, E130320P19Rik, Slil3) | |
Results | Reference |
1 | J:195145 Amaniti EM, Hasenpusch-Theil K, Li Z, Magnani D, Kessaris N, Mason JO, Theil T, Gli3 is required in Emx1(+) progenitors for the development of the corpus callosum. Dev Biol. 2013 Apr 15;376(2):113-24 |
2* | J:82500 Anselmo MA, Dalvin S, Prodhan P, Komatsuzaki K, Aidlen JT, Schnitzer JJ, Wu JY, Bernard Kinane T, Slit and robo: expression patterns in lung development. Gene Expr Patterns. 2003 Mar;3(1):13-9 |
1 | J:315765 Borrell V, Cardenas A, Ciceri G, Galceran J, Flames N, Pla R, Nobrega-Pereira S, Garcia-Frigola C, Peregrin S, Zhao Z, Ma L, Tessier-Lavigne M, Marin O, Slit/Robo signaling modulates the proliferation of central nervous system progenitors. Neuron. 2012 Oct 18;76(2):338-52 |
1 | J:264379 Cardenas A, Villalba A, de Juan Romero C, Pico E, Kyrousi C, Tzika AC, Tessier-Lavigne M, Ma L, Drukker M, Cappello S, Borrell V, Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels. Cell. 2018 Jul 26;174(3):590-606.e21 |
1 | J:73073 Chapouton P, Schuurmans C, Guillemot F, Gotz M, The transcription factor neurogenin 2 restricts cell migration from the cortex to the striatum. Development. 2001 Dec;128(24):5149-59 |
1 | J:272376 Clegg JM, Parkin HM, Mason JO, Pratt T, Heparan Sulfate Sulfation by Hs2st Restricts Astroglial Precursor Somal Translocation in Developing Mouse Forebrain by a Non-Cell-Autonomous Mechanism. J Neurosci. 2019 Feb 20;39(8):1386-1404 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1 | J:339855 Gannoun L, De Schrevel C, Belle M, Dauguet N, Achouri Y, Loriot A, Vanderaa C, Cordi S, Dili A, Heremans Y, Rooman I, Leclercq IA, Jacquemin P, Gatto L, Lemaigre FP, Axon guidance genes control hepatic artery development. Development. 2023 Aug 15;150(16):dev201642 |
1 | J:355142 Gomez-Del Arco P, Isern J, Jimenez-Carretero D, Lopez-Maderuelo D, Pineiro-Sabaris R, El Abdellaoui-Soussi F, Torroja C, Vera-Pedrosa ML, Grima-Terren M, Benguria A, Simon-Chica A, Queiro-Palou A, Dopazo A, Sanchez-Cabo F, Jalife J, de la Pompa JL, Filgueiras-Rama D, Munoz-Canoves P, Redondo JM, The G4 resolvase Dhx36 modulates cardiomyocyte differentiation and ventricular conduction system development. Nat Commun. 2024 Oct 4;15(1):8602 |
1 | J:330742 Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM, In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022 Oct 17;132(20):e156955 |
1 | J:90281 Greenberg JM, Thompson FY, Brooks SK, Shannon JM, Akeson AL, Slit and robo expression in the developing mouse lung. Dev Dyn. 2004 Jun;230(2):350-60 |
1* | J:52200 Holmes GP, Negus K, Burridge L, Raman S, Algar E, Yamada T, Little MH, Distinct but overlapping expression patterns of two vertebrate slit homologs implies functional roles in CNS development and organogenesis. Mech Dev. 1998 Dec;79(1-2):57-72 |
1* | J:71421 Loes S, Luukko K, Kvinnsland IH, Kettunen P, Slit1 is specifically expressed in the primary and secondary enamel knots during molar tooth cusp formation. Mech Dev. 2001 Sep;107(1-2):155-7 |
1 | J:217046 Magnani D, Hasenpusch-Theil K, Benadiba C, Yu T, Basson MA, Price DJ, Lebrand C, Theil T, Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Cereb Cortex. 2014 Jan;24(1):186-98 |
1 | J:154741 Prince JE, Cho JH, Dumontier E, Andrews W, Cutforth T, Tessier-Lavigne M, Parnavelas J, Cloutier JF, Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. J Neurosci. 2009 Nov 11;29(45):14211-22 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
1 | J:345833 Rodriguez-Perez LM, Lopez-de-San-Sebastian J, de Diego I, Smith A, Roales-Bujan R, Jimenez AJ, Paez-Gonzalez P, A selective defect in the glial wedge as part of the neuroepithelium disruption in hydrocephalus development in the mouse hyh model is associated with complete corpus callosum dysgenesis. Front Cell Neurosci. 2024;18:1330412 |
1 | J:246732 Saller MM, Huettl RE, Hanuschick P, Amend AL, Alberton P, Aszodi A, Huber AB, The role of Sema3-Npn-1 signaling during diaphragm innervation and muscle development. J Cell Sci. 2016 Sep 01;129(17):3295-308 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
2 | J:110263 Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM, Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat Neurosci. 2006 Jun;9(6):787-97 |
1 | J:119315 Thompson H, Barker D, Camand O, Erskine L, Slits contribute to the guidance of retinal ganglion cell axons in the mammalian optic tract. Dev Biol. 2006 Aug 15;296(2):476-84 |
1* | J:104160 Tole S, Gutin G, Bhatnagar L, Remedios R, Hebert JM, Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev Biol. 2006 Jan 1;289(1):141-51 |
1* | J:184936 Unni DK, Piper M, Moldrich RX, Gobius I, Liu S, Fothergill T, Donahoo AL, Baisden JM, Cooper HM, Richards LJ, Multiple Slits regulate the development of midline glial populations and the corpus callosum. Dev Biol. 2012 May 1;365(1):36-49 |
2 | J:199796 Wang SZ, Ibrahim LA, Kim YJ, Gibson DA, Leung HC, Yuan W, Zhang KK, Tao HW, Ma L, Zhang LI, Slit/Robo Signaling Mediates Spatial Positioning of Spiral Ganglion Neurons during Development of Cochlear Innervation. J Neurosci. 2013 Jul 24;33(30):12242-54 |
1 | J:334513 Yan K, Bormuth I, Bormuth O, Tutukova S, Renner A, Bessa P, Schaub T, Rosario M, Tarabykin V, TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6. Cereb Cortex. 2023 Feb 20;33(5):1752-1767 |
1 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
Slit3 slit guidance ligand 3 (Synonyms: b2b2362.1Clo, Slit1) | |
Results | Reference |
2* | J:82500 Anselmo MA, Dalvin S, Prodhan P, Komatsuzaki K, Aidlen JT, Schnitzer JJ, Wu JY, Bernard Kinane T, Slit and robo: expression patterns in lung development. Gene Expr Patterns. 2003 Mar;3(1):13-9 |
1 | J:264379 Cardenas A, Villalba A, de Juan Romero C, Pico E, Kyrousi C, Tzika AC, Tessier-Lavigne M, Ma L, Drukker M, Cappello S, Borrell V, Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels. Cell. 2018 Jul 26;174(3):590-606.e21 |
2 | J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5 |
1 | J:90281 Greenberg JM, Thompson FY, Brooks SK, Shannon JM, Akeson AL, Slit and robo expression in the developing mouse lung. Dev Dyn. 2004 Jun;230(2):350-60 |
1* | J:52200 Holmes GP, Negus K, Burridge L, Raman S, Algar E, Yamada T, Little MH, Distinct but overlapping expression patterns of two vertebrate slit homologs implies functional roles in CNS development and organogenesis. Mech Dev. 1998 Dec;79(1-2):57-72 |
1* | J:71421 Loes S, Luukko K, Kvinnsland IH, Kettunen P, Slit1 is specifically expressed in the primary and secondary enamel knots during molar tooth cusp formation. Mech Dev. 2001 Sep;107(1-2):155-7 |
1 | J:273473 McKey J, Bunce C, Batchvarov IS, Ornitz DM, Capel B, Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5570-5575 |
1 | J:154741 Prince JE, Cho JH, Dumontier E, Andrews W, Cutforth T, Tessier-Lavigne M, Parnavelas J, Cloutier JF, Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. J Neurosci. 2009 Nov 11;29(45):14211-22 |
1 | J:110263 Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM, Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat Neurosci. 2006 Jun;9(6):787-97 |
1* | J:184936 Unni DK, Piper M, Moldrich RX, Gobius I, Liu S, Fothergill T, Donahoo AL, Baisden JM, Cooper HM, Richards LJ, Multiple Slits regulate the development of midline glial populations and the corpus callosum. Dev Biol. 2012 May 1;365(1):36-49 |
2 | J:199796 Wang SZ, Ibrahim LA, Kim YJ, Gibson DA, Leung HC, Yuan W, Zhang KK, Tao HW, Ma L, Zhang LI, Slit/Robo Signaling Mediates Spatial Positioning of Spiral Ganglion Neurons during Development of Cochlear Innervation. J Neurosci. 2013 Jul 24;33(30):12242-54 |
Slitrk1 SLIT and NTRK-like family, member 1 (Synonyms: 3200001I04Rik) | |
Results | Reference |
1* | J:85959 Aruga J, Mikoshiba K, Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth. Mol Cell Neurosci. 2003 Sep;24(1):117-29 |
Slitrk2 SLIT and NTRK-like family, member 2 | |
Results | Reference |
1* | J:85959 Aruga J, Mikoshiba K, Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth. Mol Cell Neurosci. 2003 Sep;24(1):117-29 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Slitrk3 SLIT and NTRK-like family, member 3 (Synonyms: ST3) | |
Results | Reference |
1* | J:85959 Aruga J, Mikoshiba K, Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth. Mol Cell Neurosci. 2003 Sep;24(1):117-29 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
Slitrk4 SLIT and NTRK-like family, member 4 (Synonyms: D930039I09Rik) | |
Results | Reference |
1* | J:85959 Aruga J, Mikoshiba K, Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth. Mol Cell Neurosci. 2003 Sep;24(1):117-29 |
1* | J:147117 Cheng TW, Gong Q, Secreted TARSH regulates olfactory mitral cell dendritic complexity. Eur J Neurosci. 2009 Mar;29(6):1083-95 |
Slitrk5 SLIT and NTRK-like family, member 5 (Synonyms: 2610019D03Rik) | |
Results | Reference |
1* | J:85959 Aruga J, Mikoshiba K, Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth. Mol Cell Neurosci. 2003 Sep;24(1):117-29 |
1 | J:330742 Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM, In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022 Oct 17;132(20):e156955 |
Slitrk6 SLIT and NTRK-like family, member 6 (Synonyms: 4832410J21Rik) | |
Results | Reference |
1* | J:85959 Aruga J, Mikoshiba K, Identification and characterization of Slitrk, a novel neuronal transmembrane protein family controlling neurite outgrowth. Mol Cell Neurosci. 2003 Sep;24(1):117-29 |
1 | J:155405 Katayama K, Zine A, Ota M, Matsumoto Y, Inoue T, Fritzsch B, Aruga J, Disorganized innervation and neuronal loss in the inner ear of Slitrk6-deficient mice. PLoS One. 2009;4(11):e7786 |
Slmap sarcolemma associated protein (Synonyms: D330001L02Rik, Miranda, mKIAA1601, Slap) | |
Results | Reference |
1 | J:358347 Dias AP, Rehmani T, Salih M, Tuana B, Tail-anchored membrane protein SLMAP3 is essential for targeting centrosomal proteins to the nuclear envelope in skeletal myogenesis. Open Biol. 2024 Oct;14(10):240094 |
Slu7 SLU7 splicing factor homolog (S. cerevisiae) (Synonyms: D11Ertd730e, D3Bwg0878e, MGC:31026) | |
Results | Reference |
1 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
Slx Sycp3 like X-linked (Synonyms: EG664958, Xmr) | |
Results | Reference |
1* | J:138760 Reynard LN, Turner JM, Cocquet J, Mahadevaiah SK, Toure A, Hoog C, Burgoyne PS, Expression analysis of the mouse multi-copy X-linked gene Xlr-related, meiosis-regulated (Xmr), reveals that Xmr encodes a spermatid-expressed cytoplasmic protein, SLX/XMR. Biol Reprod. 2007 Aug;77(2):329-35 |
Slxl1 Slx-like 1 (Synonyms: 4930527E24Rik, OTTMUSG00000017407) | |
Results | Reference |
1* | J:138760 Reynard LN, Turner JM, Cocquet J, Mahadevaiah SK, Toure A, Hoog C, Burgoyne PS, Expression analysis of the mouse multi-copy X-linked gene Xlr-related, meiosis-regulated (Xmr), reveals that Xmr encodes a spermatid-expressed cytoplasmic protein, SLX/XMR. Biol Reprod. 2007 Aug;77(2):329-35 |
Smad1 SMAD family member 1 (Synonyms: Madh1, Madr1, Smad 1) | |
Results | Reference |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
1 | J:282102 Canizares MA, Albors AR, Singer G, Suttie N, Gorkic M, Felts P, Storey KG, Multiple steps characterise ventricular layer attrition to form the ependymal cell lining of the adult mouse spinal cord central canal. J Anat. 2019 Oct 31; |
1 | J:98474 Chen C, Chen H, Sun J, Bringas P Jr, Chen Y, Warburton D, Shi W, Smad1 expression and function during mouse embryonic lung branching morphogenesis. Am J Physiol Lung Cell Mol Physiol. 2005 Jun;288(6):L1033-9 |
1 | J:217413 Choe Y, Huynh T, Pleasure SJ, Migration of oligodendrocyte progenitor cells is controlled by transforming growth factor beta family proteins during corticogenesis. J Neurosci. 2014 Nov 5;34(45):14973-83 |
1* | J:93808 Chuva de Sousa Lopes SM, Feijen A, Korving J, Korchynskyi O, Larsson J, Karlsson S, ten Dijke P, Lyons KM, Goldschmeding R, Doevendans P, Mummery CL, Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction. Dev Dyn. 2004 Nov;231(3):542-50 |
2 | J:206944 Clegg JM, Conway CD, Howe KM, Price DJ, Mason JO, Turnbull JE, Basson MA, Pratt T, Heparan sulfotransferases Hs6st1 and Hs2st Keep Erk in check for mouse corpus callosum development. J Neurosci. 2014 Feb 5;34(6):2389-401 |
1 | J:310908 Deng J, Wang S, Li N, Chen X, Wang B, Liu H, Zhu L, Cong W, Xiao J, Liu C, Noggin Overexpression Impairs the Development of Muscles, Tendons, and Aponeurosis in Soft Palates by Disrupting BMP-Smad and Shh-Gli1 Signaling. Front Cell Dev Biol. 2021;9:711334 |
1 | J:215675 Deng M, Luo XJ, Pan L, Yang H, Xie X, Liang G, Huang L, Hu F, Kiernan AE, Gan L, LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea. J Neurosci. 2014 Jul 23;34(30):10072-7 |
1 | J:164103 Du Y, Xiao Q, Yip HK, Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the smad/id cascade. Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3764-73 |
1* | J:198483 Finelli MJ, Murphy KJ, Chen L, Zou H, Differential phosphorylation of Smad1 integrates BMP and neurotrophin pathways through Erk/Dusp in axon development. Cell Rep. 2013 May 30;3(5):1592-606 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:90584 Horiki M, Imamura T, Okamoto M, Hayashi M, Murai J, Myoui A, Ochi T, Miyazono K, Yoshikawa H, Tsumaki N, Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia. J Cell Biol. 2004 Jun 10;165(3):433-45 |
1 | J:150516 Hu Z, Wang C, Xiao Y, Sheng N, Chen Y, Xu Y, Zhang L, Mo W, Jing N, Hu G, NDST1-dependent heparan sulfate regulates BMP signaling and internalization in lung development. J Cell Sci. 2009 Apr 15;122(Pt 8):1145-54 |
2 | J:200638 Islam SS, Mokhtari RB, Kumar S, Maalouf J, Arab S, Yeger H, Farhat WA, Spatio-temporal distribution of Smads and role of Smads/TGF-beta/BMP-4 in the regulation of mouse bladder organogenesis. PLoS One. 2013;8(4):e61340 |
1 | J:294228 Kalailingam P, Wang KQ, Toh XR, Nguyen TQ, Chandrakanthan M, Hasan Z, Habib C, Schif A, Radio FC, Dallapiccola B, Weiss K, Nguyen LN, Deficiency of MFSD7c results in microcephaly-associated vasculopathy in Fowler syndrome. J Clin Invest. 2020 Aug 3;130(8):4081-4093 |
1 | J:308704 Kiyokawa H, Yamaoka A, Matsuoka C, Tokuhara T, Abe T, Morimoto M, Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfbeta-Id2 axis, for tissue regeneration. Dev Cell. 2021 Jul 12;56(13):1917-1929.e9 |
1* | J:238086 Kusano R, Fujita K, Shinoda Y, Nagaura Y, Kiyonari H, Abe T, Watanabe T, Matsui Y, Fukaya M, Sakagami H, Sato T, Funahashi JI, Ohnishi M, Tamura S, Kobayashi T, Targeted disruption of the mouse protein phosphatase ppm1l gene leads to structural abnormalities in the brain. FEBS Lett. 2016 Oct;590(20):3606-3615 |
1 | J:348857 Li Z, Liu G, Yang L, Sun M, Zhang Z, Xu Z, Gao Y, Jiang X, Su Z, Li X, Yang Z, BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period. Protein Cell. 2024 Jan 3;15(1):21-35 |
1 | J:236373 Ludtke TH, Rudat C, Wojahn I, Weiss AC, Kleppa MJ, Kurz J, Farin HF, Moon A, Christoffels VM, Kispert A, Tbx2 and Tbx3 Act Downstream of Shh to Maintain Canonical Wnt Signaling during Branching Morphogenesis of the Murine Lung. Dev Cell. 2016 Oct 24;39(2):239-253 |
1 | J:193853 Makino Y, Takahashi Y, Tanabe R, Tamamura Y, Watanabe T, Haraikawa M, Hamagaki M, Hata K, Kanno J, Yoneda T, Saga Y, Goseki-Sone M, Kaneko K, Yamaguchi A, Iimura T, Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone. 2013 Mar;53(1):248-58 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:297164 Nie X, Zheng J, Cruciger M, Yang P, Mao JJ, mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev Biol. 2020 Nov 1;467(1-2):77-87 |
1 | J:214075 Norrie JL, Lewandowski JP, Bouldin CM, Amarnath S, Li Q, Vokes MS, Ehrlich LI, Harfe BD, Vokes SA, Dynamics of BMP signaling in limb bud mesenchyme and polydactyly. Dev Biol. 2014 Sep 15;393(2):270-81 |
1 | J:144348 Ohazama A, Johnson EB, Ota MS, Choi HJ, Porntaveetus T, Oommen S, Itoh N, Eto K, Gritli-Linde A, Herz J, Sharpe PT, Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One. 2008;3(12):e4092 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
1 | J:231738 Reed-Geaghan EG, Wright MC, See LA, Adelman PC, Lee KH, Koerber HR, Maricich SM, Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. J Neurosci. 2016 Apr 13;36(15):4362-76 |
1 | J:205632 Saito A, Kanemoto S, Kawasaki N, Asada R, Iwamoto H, Oki M, Miyagi H, Izumi S, Sanosaka T, Nakashima K, Imaizumi K, Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun. 2012;3:967 |
1 | J:302551 Schlesinger SY, Seo S, Pryce BA, Tufa SF, Keene DR, Huang AH, Schweitzer R, Loss of Smad4 in the scleraxis cell lineage results in postnatal joint contracture. Dev Biol. 2021 Feb;470:108-120 |
1 | J:220362 Sun Y, Nakanishi M, Sato F, Oikawa K, Muragaki Y, Zhou G, Trps1 deficiency inhibits the morphogenesis of secondary hair follicles via decreased Noggin expression. Biochem Biophys Res Commun. 2015 Jan 16;456(3):721-6 |
1 | J:144194 Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:172689 Wang M, Jin H, Tang D, Huang S, Zuscik MJ, Chen D, Smad1 plays an essential role in bone development and postnatal bone formation. Osteoarthritis Cartilage. 2011 Jun;19(6):751-62 |
1 | J:278336 Wang W, Chun H, Baek J, Sadik JE, Shirazyan A, Razavi P, Lopez N, Lyons KM, The TGFbeta type I receptor TGFbetaRI functions as an inhibitor of BMP signaling in cartilage. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15570-15579 |
2 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
2 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
1 | J:316215 Zhou N, Li N, Liu J, Wang Y, Gao J, Wu Y, Chen X, Liu C, Xiao J, Persistent Wnt/beta-catenin signaling in mouse epithelium induces the ectopic Dspp expression in cheek mesenchyme. Organogenesis. 2019;15(1):1-12 |
1 | J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687 |
Smad2 SMAD family member 2 (Synonyms: 7120426M23Rik, Madh2, Madr2, Smad 2) | |
Results | Reference |
1* | J:93808 Chuva de Sousa Lopes SM, Feijen A, Korving J, Korchynskyi O, Larsson J, Karlsson S, ten Dijke P, Lyons KM, Goldschmeding R, Doevendans P, Mummery CL, Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction. Dev Dyn. 2004 Nov;231(3):542-50 |
1 | J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400 |
1 | J:139005 Geske MJ, Zhang X, Patel KK, Ornitz DM, Stappenbeck TS, Fgf9 signaling regulates small intestinal elongation and mesenchymal development. Development. 2008 Sep;135(17):2959-68 |
1 | J:236173 Guo W, Benlhabib H, Mendelson CR, The MicroRNA 29 Family Promotes Type II Cell Differentiation in Developing Lung. Mol Cell Biol. 2016 Aug 15;36(16):2141 |
2 | J:200638 Islam SS, Mokhtari RB, Kumar S, Maalouf J, Arab S, Yeger H, Farhat WA, Spatio-temporal distribution of Smads and role of Smads/TGF-beta/BMP-4 in the regulation of mouse bladder organogenesis. PLoS One. 2013;8(4):e61340 |
1 | J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47 |
1 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
1 | J:250062 Li A, Ma S, Smith SM, Lee MK, Fischer A, Borok Z, Bellusci S, Li C, Minoo P, Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate. BMC Biol. 2016 Mar 16;14:19 |
1* | J:257228 Li S, Pan Y, Differential expression of transforming growth factor-beta1, connective tissue growth factor, phosphorylated-SMAD2/3 and phosphorylated-ERK1/2 during mouse tooth development. J Mol Histol. 2017 Dec;48(5-6):347-355 |
1 | J:236373 Ludtke TH, Rudat C, Wojahn I, Weiss AC, Kleppa MJ, Kurz J, Farin HF, Moon A, Christoffels VM, Kispert A, Tbx2 and Tbx3 Act Downstream of Shh to Maintain Canonical Wnt Signaling during Branching Morphogenesis of the Murine Lung. Dev Cell. 2016 Oct 24;39(2):239-253 |
1 | J:193853 Makino Y, Takahashi Y, Tanabe R, Tamamura Y, Watanabe T, Haraikawa M, Hamagaki M, Hata K, Kanno J, Yoneda T, Saga Y, Goseki-Sone M, Kaneko K, Yamaguchi A, Iimura T, Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone. 2013 Mar;53(1):248-58 |
2 | J:214978 Nie X, Arend LJ, Novel roles of Pkd2 in male reproductive system development. Differentiation. 2014 Mar-Apr;87(3-4):161-71 |
1 | J:134924 Spagnoli A, O'Rear L, Chandler RL, Granero-Molto F, Mortlock DP, Gorska AE, Weis JA, Longobardi L, Chytil A, Shimer K, Moses HL, TGF-beta signaling is essential for joint morphogenesis. J Cell Biol. 2007 Jun 18;177(6):1105-17 |
1 | J:156253 Tateossian H, Hardisty-Hughes RE, Morse S, Romero MR, Hilton H, Dean C, Brown SD, Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant. Pathogenetics. 2009;2(1):5 |
1* | J:167709 Todorovic V, Finnegan E, Freyer L, Zilberberg L, Ota M, Rifkin DB, Long form of latent TGF-beta binding protein 1 (Ltbp1L) regulates cardiac valve development. Dev Dyn. 2011 Jan;240(1):176-87 |
1 | J:278336 Wang W, Chun H, Baek J, Sadik JE, Shirazyan A, Razavi P, Lopez N, Lyons KM, The TGFbeta type I receptor TGFbetaRI functions as an inhibitor of BMP signaling in cartilage. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15570-15579 |
1* | J:236232 Wang W, Song B, Anbarchian T, Shirazyan A, Sadik JE, Lyons KM, Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate. PLoS Genet. 2016 Oct;12(10):e1006352 |
1 | J:283373 Zhang W, Shen Z, Xing Y, Zhao H, Liang Y, Chen J, Zhong X, Shi L, Wan X, Zhou J, Tang S, MiR-106a-5p modulates apoptosis and metabonomics changes by TGF-beta/Smad signaling pathway in cleft palate. Exp Cell Res. 2020 Jan 15;386(2):111734 |
1 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
Smad3 SMAD family member 3 (Synonyms: Madh3, Smad 3) | |
Results | Reference |
1 | J:311884 Berthet E, Chen C, Butcher K, Schneider RA, Alliston T, Amirtharajah M, Smad3 binds Scleraxis and Mohawk and regulates tendon matrix organization. J Orthop Res. 2013 Sep;31(9):1475-83 |
1 | J:139005 Geske MJ, Zhang X, Patel KK, Ornitz DM, Stappenbeck TS, Fgf9 signaling regulates small intestinal elongation and mesenchymal development. Development. 2008 Sep;135(17):2959-68 |
3 | J:196581 Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G, The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-beta signaling. Dev Biol. 2013 May 15;377(2):415-27 |
2 | J:200638 Islam SS, Mokhtari RB, Kumar S, Maalouf J, Arab S, Yeger H, Farhat WA, Spatio-temporal distribution of Smads and role of Smads/TGF-beta/BMP-4 in the regulation of mouse bladder organogenesis. PLoS One. 2013;8(4):e61340 |
1 | J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47 |
1* | J:257228 Li S, Pan Y, Differential expression of transforming growth factor-beta1, connective tissue growth factor, phosphorylated-SMAD2/3 and phosphorylated-ERK1/2 during mouse tooth development. J Mol Histol. 2017 Dec;48(5-6):347-355 |
1 | J:236373 Ludtke TH, Rudat C, Wojahn I, Weiss AC, Kleppa MJ, Kurz J, Farin HF, Moon A, Christoffels VM, Kispert A, Tbx2 and Tbx3 Act Downstream of Shh to Maintain Canonical Wnt Signaling during Branching Morphogenesis of the Murine Lung. Dev Cell. 2016 Oct 24;39(2):239-253 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
1 | J:156253 Tateossian H, Hardisty-Hughes RE, Morse S, Romero MR, Hilton H, Dean C, Brown SD, Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant. Pathogenetics. 2009;2(1):5 |
1 | J:278336 Wang W, Chun H, Baek J, Sadik JE, Shirazyan A, Razavi P, Lopez N, Lyons KM, The TGFbeta type I receptor TGFbetaRI functions as an inhibitor of BMP signaling in cartilage. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15570-15579 |
1* | J:236232 Wang W, Song B, Anbarchian T, Shirazyan A, Sadik JE, Lyons KM, Smad2 and Smad3 Regulate Chondrocyte Proliferation and Differentiation in the Growth Plate. PLoS Genet. 2016 Oct;12(10):e1006352 |
2 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
1 | J:267715 Wiwatpanit T, Lorenzen SM, Cantu JA, Foo CZ, Hogan AK, Marquez F, Clancy JC, Schipma MJ, Cheatham MA, Duggan A, Garcia-Anoveros J, Trans-differentiation of outer hair cells into inner hair cells in the absence of INSM1. Nature. 2018 Nov;563(7733):691-695 |
1 | J:283373 Zhang W, Shen Z, Xing Y, Zhao H, Liang Y, Chen J, Zhong X, Shi L, Wan X, Zhou J, Tang S, MiR-106a-5p modulates apoptosis and metabonomics changes by TGF-beta/Smad signaling pathway in cleft palate. Exp Cell Res. 2020 Jan 15;386(2):111734 |
1 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
Smad4 SMAD family member 4 (Synonyms: D18Wsu70e, Dpc4, DPC4, Madh4, Smad 4) | |
Results | Reference |
1 | J:184924 Fernandes M, Antoine M, Hebert JM, SMAD4 is essential for generating subtypes of neurons during cerebellar development. Dev Biol. 2012 May 1;365(1):82-90 |
2 | J:200638 Islam SS, Mokhtari RB, Kumar S, Maalouf J, Arab S, Yeger H, Farhat WA, Spatio-temporal distribution of Smads and role of Smads/TGF-beta/BMP-4 in the regulation of mouse bladder organogenesis. PLoS One. 2013;8(4):e61340 |
1 | J:294228 Kalailingam P, Wang KQ, Toh XR, Nguyen TQ, Chandrakanthan M, Hasan Z, Habib C, Schif A, Radio FC, Dallapiccola B, Weiss K, Nguyen LN, Deficiency of MFSD7c results in microcephaly-associated vasculopathy in Fowler syndrome. J Clin Invest. 2020 Aug 3;130(8):4081-4093 |
1 | J:122566 Simirskii VN, Wang Y, Duncan MK, Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype. Dev Biol. 2007 Jun 15;306(2):658-68 |
1 | J:156253 Tateossian H, Hardisty-Hughes RE, Morse S, Romero MR, Hilton H, Dean C, Brown SD, Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant. Pathogenetics. 2009;2(1):5 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:218980 Yan J, Zhang L, Xu J, Sultana N, Hu J, Cai X, Li J, Xu PX, Cai CL, Smad4 regulates ureteral smooth muscle cell differentiation during mouse embryogenesis. PLoS One. 2014;9(8):e104503 |
1 | J:283373 Zhang W, Shen Z, Xing Y, Zhao H, Liang Y, Chen J, Zhong X, Shi L, Wan X, Zhou J, Tang S, MiR-106a-5p modulates apoptosis and metabonomics changes by TGF-beta/Smad signaling pathway in cleft palate. Exp Cell Res. 2020 Jan 15;386(2):111734 |
Smad5 SMAD family member 5 (Synonyms: Madh5, MusMLP, Smad 5) | |
Results | Reference |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
1 | J:282102 Canizares MA, Albors AR, Singer G, Suttie N, Gorkic M, Felts P, Storey KG, Multiple steps characterise ventricular layer attrition to form the ependymal cell lining of the adult mouse spinal cord central canal. J Anat. 2019 Oct 31; |
1 | J:217413 Choe Y, Huynh T, Pleasure SJ, Migration of oligodendrocyte progenitor cells is controlled by transforming growth factor beta family proteins during corticogenesis. J Neurosci. 2014 Nov 5;34(45):14973-83 |
1* | J:93808 Chuva de Sousa Lopes SM, Feijen A, Korving J, Korchynskyi O, Larsson J, Karlsson S, ten Dijke P, Lyons KM, Goldschmeding R, Doevendans P, Mummery CL, Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction. Dev Dyn. 2004 Nov;231(3):542-50 |
2 | J:206944 Clegg JM, Conway CD, Howe KM, Price DJ, Mason JO, Turnbull JE, Basson MA, Pratt T, Heparan sulfotransferases Hs6st1 and Hs2st Keep Erk in check for mouse corpus callosum development. J Neurosci. 2014 Feb 5;34(6):2389-401 |
1 | J:310908 Deng J, Wang S, Li N, Chen X, Wang B, Liu H, Zhu L, Cong W, Xiao J, Liu C, Noggin Overexpression Impairs the Development of Muscles, Tendons, and Aponeurosis in Soft Palates by Disrupting BMP-Smad and Shh-Gli1 Signaling. Front Cell Dev Biol. 2021;9:711334 |
1 | J:215675 Deng M, Luo XJ, Pan L, Yang H, Xie X, Liang G, Huang L, Hu F, Kiernan AE, Gan L, LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea. J Neurosci. 2014 Jul 23;34(30):10072-7 |
1 | J:164103 Du Y, Xiao Q, Yip HK, Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the smad/id cascade. Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3764-73 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:90584 Horiki M, Imamura T, Okamoto M, Hayashi M, Murai J, Myoui A, Ochi T, Miyazono K, Yoshikawa H, Tsumaki N, Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia. J Cell Biol. 2004 Jun 10;165(3):433-45 |
2 | J:200638 Islam SS, Mokhtari RB, Kumar S, Maalouf J, Arab S, Yeger H, Farhat WA, Spatio-temporal distribution of Smads and role of Smads/TGF-beta/BMP-4 in the regulation of mouse bladder organogenesis. PLoS One. 2013;8(4):e61340 |
1 | J:294228 Kalailingam P, Wang KQ, Toh XR, Nguyen TQ, Chandrakanthan M, Hasan Z, Habib C, Schif A, Radio FC, Dallapiccola B, Weiss K, Nguyen LN, Deficiency of MFSD7c results in microcephaly-associated vasculopathy in Fowler syndrome. J Clin Invest. 2020 Aug 3;130(8):4081-4093 |
1 | J:308704 Kiyokawa H, Yamaoka A, Matsuoka C, Tokuhara T, Abe T, Morimoto M, Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfbeta-Id2 axis, for tissue regeneration. Dev Cell. 2021 Jul 12;56(13):1917-1929.e9 |
1* | J:238086 Kusano R, Fujita K, Shinoda Y, Nagaura Y, Kiyonari H, Abe T, Watanabe T, Matsui Y, Fukaya M, Sakagami H, Sato T, Funahashi JI, Ohnishi M, Tamura S, Kobayashi T, Targeted disruption of the mouse protein phosphatase ppm1l gene leads to structural abnormalities in the brain. FEBS Lett. 2016 Oct;590(20):3606-3615 |
1 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
1 | J:348857 Li Z, Liu G, Yang L, Sun M, Zhang Z, Xu Z, Gao Y, Jiang X, Su Z, Li X, Yang Z, BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period. Protein Cell. 2024 Jan 3;15(1):21-35 |
1 | J:236373 Ludtke TH, Rudat C, Wojahn I, Weiss AC, Kleppa MJ, Kurz J, Farin HF, Moon A, Christoffels VM, Kispert A, Tbx2 and Tbx3 Act Downstream of Shh to Maintain Canonical Wnt Signaling during Branching Morphogenesis of the Murine Lung. Dev Cell. 2016 Oct 24;39(2):239-253 |
1 | J:193853 Makino Y, Takahashi Y, Tanabe R, Tamamura Y, Watanabe T, Haraikawa M, Hamagaki M, Hata K, Kanno J, Yoneda T, Saga Y, Goseki-Sone M, Kaneko K, Yamaguchi A, Iimura T, Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone. 2013 Mar;53(1):248-58 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:297164 Nie X, Zheng J, Cruciger M, Yang P, Mao JJ, mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev Biol. 2020 Nov 1;467(1-2):77-87 |
1 | J:214075 Norrie JL, Lewandowski JP, Bouldin CM, Amarnath S, Li Q, Vokes MS, Ehrlich LI, Harfe BD, Vokes SA, Dynamics of BMP signaling in limb bud mesenchyme and polydactyly. Dev Biol. 2014 Sep 15;393(2):270-81 |
1 | J:144348 Ohazama A, Johnson EB, Ota MS, Choi HJ, Porntaveetus T, Oommen S, Itoh N, Eto K, Gritli-Linde A, Herz J, Sharpe PT, Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One. 2008;3(12):e4092 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
1 | J:231738 Reed-Geaghan EG, Wright MC, See LA, Adelman PC, Lee KH, Koerber HR, Maricich SM, Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. J Neurosci. 2016 Apr 13;36(15):4362-76 |
1 | J:205632 Saito A, Kanemoto S, Kawasaki N, Asada R, Iwamoto H, Oki M, Miyagi H, Izumi S, Sanosaka T, Nakashima K, Imaizumi K, Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun. 2012;3:967 |
1 | J:302551 Schlesinger SY, Seo S, Pryce BA, Tufa SF, Keene DR, Huang AH, Schweitzer R, Loss of Smad4 in the scleraxis cell lineage results in postnatal joint contracture. Dev Biol. 2021 Feb;470:108-120 |
1 | J:220362 Sun Y, Nakanishi M, Sato F, Oikawa K, Muragaki Y, Zhou G, Trps1 deficiency inhibits the morphogenesis of secondary hair follicles via decreased Noggin expression. Biochem Biophys Res Commun. 2015 Jan 16;456(3):721-6 |
1 | J:144194 Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:278336 Wang W, Chun H, Baek J, Sadik JE, Shirazyan A, Razavi P, Lopez N, Lyons KM, The TGFbeta type I receptor TGFbetaRI functions as an inhibitor of BMP signaling in cartilage. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15570-15579 |
2 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
2 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
1 | J:316215 Zhou N, Li N, Liu J, Wang Y, Gao J, Wu Y, Chen X, Liu C, Xiao J, Persistent Wnt/beta-catenin signaling in mouse epithelium induces the ectopic Dspp expression in cheek mesenchyme. Organogenesis. 2019;15(1):1-12 |
1 | J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687 |
Smad6 SMAD family member 6 (Synonyms: b2b390Clo, Madh6, Smad 6) | |
Results | Reference |
1* | J:86790 Gitler AD, Lu MM, Jiang YQ, Epstein JA, Gruber PJ, Molecular markers of cardiac endocardial cushion development. Dev Dyn. 2003 Dec;228(4):643-50 |
1 | J:90584 Horiki M, Imamura T, Okamoto M, Hayashi M, Murai J, Myoui A, Ochi T, Miyazono K, Yoshikawa H, Tsumaki N, Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia. J Cell Biol. 2004 Jun 10;165(3):433-45 |
2 | J:200638 Islam SS, Mokhtari RB, Kumar S, Maalouf J, Arab S, Yeger H, Farhat WA, Spatio-temporal distribution of Smads and role of Smads/TGF-beta/BMP-4 in the regulation of mouse bladder organogenesis. PLoS One. 2013;8(4):e61340 |
1* | J:142326 Iwai T, Murai J, Yoshikawa H, Tsumaki N, Smad7 Inhibits chondrocyte differentiation at multiple steps during endochondral bone formation and down-regulates p38 MAPK pathways. J Biol Chem. 2008 Oct 3;283(40):27154-64 |
1 | J:342552 Kulikauskas MR, Oatley M, Yu T, Liu Z, Matsumura L, Kidder E, Ruter D, Bautch VL, Endothelial cell SMAD6 balances Alk1 function to regulate adherens junctions and hepatic vascular development. Development. 2023 Nov 1;150(21) |
1 | J:122566 Simirskii VN, Wang Y, Duncan MK, Conditional deletion of beta1-integrin from the developing lens leads to loss of the lens epithelial phenotype. Dev Biol. 2007 Jun 15;306(2):658-68 |
Smad7 SMAD family member 7 (Synonyms: Madh7) | |
Results | Reference |
1 | J:145777 Chen Q, Chen H, Zheng D, Kuang C, Fang H, Zou B, Zhu W, Bu G, Jin T, Wang Z, Zhang X, Chen J, Field LJ, Rubart M, Shou W, Chen Y, Smad7 is required for the development and function of the heart. J Biol Chem. 2009 Jan 2;284(1):292-300 |
1 | J:198451 El-Gohary Y, Tulachan S, Guo P, Welsh C, Wiersch J, Prasadan K, Paredes J, Shiota C, Xiao X, Wada Y, Diaz M, Gittes G, Smad signaling pathways regulate pancreatic endocrine development. Dev Biol. 2013 Jun 15;378(2):83-93 |
3 | J:196581 Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G, The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-beta signaling. Dev Biol. 2013 May 15;377(2):415-27 |
2 | J:200638 Islam SS, Mokhtari RB, Kumar S, Maalouf J, Arab S, Yeger H, Farhat WA, Spatio-temporal distribution of Smads and role of Smads/TGF-beta/BMP-4 in the regulation of mouse bladder organogenesis. PLoS One. 2013;8(4):e61340 |
2* | J:142326 Iwai T, Murai J, Yoshikawa H, Tsumaki N, Smad7 Inhibits chondrocyte differentiation at multiple steps during endochondral bone formation and down-regulates p38 MAPK pathways. J Biol Chem. 2008 Oct 3;283(40):27154-64 |
Smad9 SMAD family member 9 (Synonyms: MADH6, Madh9, SMAD8A, SMAD8B) | |
Results | Reference |
1* | J:119296 Arnold SJ, Maretto S, Islam A, Bikoff EK, Robertson EJ, Dose-dependent Smad1, Smad5 and Smad8 signaling in the early mouse embryo. Dev Biol. 2006 Aug 1;296(1):104-18 |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
1 | J:217413 Choe Y, Huynh T, Pleasure SJ, Migration of oligodendrocyte progenitor cells is controlled by transforming growth factor beta family proteins during corticogenesis. J Neurosci. 2014 Nov 5;34(45):14973-83 |
1* | J:93808 Chuva de Sousa Lopes SM, Feijen A, Korving J, Korchynskyi O, Larsson J, Karlsson S, ten Dijke P, Lyons KM, Goldschmeding R, Doevendans P, Mummery CL, Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction. Dev Dyn. 2004 Nov;231(3):542-50 |
1 | J:310908 Deng J, Wang S, Li N, Chen X, Wang B, Liu H, Zhu L, Cong W, Xiao J, Liu C, Noggin Overexpression Impairs the Development of Muscles, Tendons, and Aponeurosis in Soft Palates by Disrupting BMP-Smad and Shh-Gli1 Signaling. Front Cell Dev Biol. 2021;9:711334 |
1 | J:215675 Deng M, Luo XJ, Pan L, Yang H, Xie X, Liang G, Huang L, Hu F, Kiernan AE, Gan L, LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea. J Neurosci. 2014 Jul 23;34(30):10072-7 |
1 | J:164103 Du Y, Xiao Q, Yip HK, Regulation of retinal progenitor cell differentiation by bone morphogenetic protein 4 is mediated by the smad/id cascade. Invest Ophthalmol Vis Sci. 2010 Jul;51(7):3764-73 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:90584 Horiki M, Imamura T, Okamoto M, Hayashi M, Murai J, Myoui A, Ochi T, Miyazono K, Yoshikawa H, Tsumaki N, Smad6/Smurf1 overexpression in cartilage delays chondrocyte hypertrophy and causes dwarfism with osteopenia. J Cell Biol. 2004 Jun 10;165(3):433-45 |
1 | J:150213 Huang Z, Wang D, Ihida-Stansbury K, Jones PL, Martin JF, Defective pulmonary vascular remodeling in Smad8 mutant mice. Hum Mol Genet. 2009 Aug 1;18(15):2791-801 |
2 | J:200638 Islam SS, Mokhtari RB, Kumar S, Maalouf J, Arab S, Yeger H, Farhat WA, Spatio-temporal distribution of Smads and role of Smads/TGF-beta/BMP-4 in the regulation of mouse bladder organogenesis. PLoS One. 2013;8(4):e61340 |
1 | J:308704 Kiyokawa H, Yamaoka A, Matsuoka C, Tokuhara T, Abe T, Morimoto M, Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfbeta-Id2 axis, for tissue regeneration. Dev Cell. 2021 Jul 12;56(13):1917-1929.e9 |
1* | J:238086 Kusano R, Fujita K, Shinoda Y, Nagaura Y, Kiyonari H, Abe T, Watanabe T, Matsui Y, Fukaya M, Sakagami H, Sato T, Funahashi JI, Ohnishi M, Tamura S, Kobayashi T, Targeted disruption of the mouse protein phosphatase ppm1l gene leads to structural abnormalities in the brain. FEBS Lett. 2016 Oct;590(20):3606-3615 |
1 | J:348857 Li Z, Liu G, Yang L, Sun M, Zhang Z, Xu Z, Gao Y, Jiang X, Su Z, Li X, Yang Z, BMP7 expression in mammalian cortical radial glial cells increases the length of the neurogenic period. Protein Cell. 2024 Jan 3;15(1):21-35 |
1 | J:236373 Ludtke TH, Rudat C, Wojahn I, Weiss AC, Kleppa MJ, Kurz J, Farin HF, Moon A, Christoffels VM, Kispert A, Tbx2 and Tbx3 Act Downstream of Shh to Maintain Canonical Wnt Signaling during Branching Morphogenesis of the Murine Lung. Dev Cell. 2016 Oct 24;39(2):239-253 |
1 | J:193853 Makino Y, Takahashi Y, Tanabe R, Tamamura Y, Watanabe T, Haraikawa M, Hamagaki M, Hata K, Kanno J, Yoneda T, Saga Y, Goseki-Sone M, Kaneko K, Yamaguchi A, Iimura T, Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone. 2013 Mar;53(1):248-58 |
1* | J:297164 Nie X, Zheng J, Cruciger M, Yang P, Mao JJ, mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev Biol. 2020 Nov 1;467(1-2):77-87 |
1 | J:214075 Norrie JL, Lewandowski JP, Bouldin CM, Amarnath S, Li Q, Vokes MS, Ehrlich LI, Harfe BD, Vokes SA, Dynamics of BMP signaling in limb bud mesenchyme and polydactyly. Dev Biol. 2014 Sep 15;393(2):270-81 |
1 | J:144348 Ohazama A, Johnson EB, Ota MS, Choi HJ, Porntaveetus T, Oommen S, Itoh N, Eto K, Gritli-Linde A, Herz J, Sharpe PT, Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One. 2008;3(12):e4092 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
1 | J:231738 Reed-Geaghan EG, Wright MC, See LA, Adelman PC, Lee KH, Koerber HR, Maricich SM, Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. J Neurosci. 2016 Apr 13;36(15):4362-76 |
1 | J:205632 Saito A, Kanemoto S, Kawasaki N, Asada R, Iwamoto H, Oki M, Miyagi H, Izumi S, Sanosaka T, Nakashima K, Imaizumi K, Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun. 2012;3:967 |
1 | J:302551 Schlesinger SY, Seo S, Pryce BA, Tufa SF, Keene DR, Huang AH, Schweitzer R, Loss of Smad4 in the scleraxis cell lineage results in postnatal joint contracture. Dev Biol. 2021 Feb;470:108-120 |
1 | J:220362 Sun Y, Nakanishi M, Sato F, Oikawa K, Muragaki Y, Zhou G, Trps1 deficiency inhibits the morphogenesis of secondary hair follicles via decreased Noggin expression. Biochem Biophys Res Commun. 2015 Jan 16;456(3):721-6 |
1 | J:144194 Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:278336 Wang W, Chun H, Baek J, Sadik JE, Shirazyan A, Razavi P, Lopez N, Lyons KM, The TGFbeta type I receptor TGFbetaRI functions as an inhibitor of BMP signaling in cartilage. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15570-15579 |
2 | J:258463 Wang Y, Terrell AM, Riggio BA, Anand D, Lachke SA, Duncan MK, beta1-Integrin Deletion From the Lens Activates Cellular Stress Responses Leading to Apoptosis and Fibrosis. Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3896-3922 |
2 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
1 | J:316215 Zhou N, Li N, Liu J, Wang Y, Gao J, Wu Y, Chen X, Liu C, Xiao J, Persistent Wnt/beta-catenin signaling in mouse epithelium induces the ectopic Dspp expression in cheek mesenchyme. Organogenesis. 2019;15(1):1-12 |
1 | J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687 |
Smarca2 SWI/SNF related BAF chromatin remodeling complex subunit ATPase 2 (Synonyms: 2610209L14Rik, brm, Snf2l2) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
Smarca4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 (Synonyms: b2b508.1Clo, b2b692Clo, Brg1, SNF2beta, SW1/SNF) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
1 | J:349032 Gobel C, Schoof M, Holdhof D, Spohn M, Schuller U, SMARCA4 Loss and Mutated beta-Catenin Induce Proliferative Lesions in the Murine Embryonic Cerebellum. J Neurosci. 2024 Apr 10;44(15) |
1 | J:168483 He S, Pirity MK, Wang WL, Wolf L, Chauhan BK, Cveklova K, Tamm ER, Ashery-Padan R, Metzger D, Nakai A, Chambon P, Zavadil J, Cvekl A, Chromatin remodeling enzyme Brg1 is required for mouse lens fiber cell terminal differentiation and its denucleation. Epigenetics Chromatin. 2010;3(1):21 |
1 | J:334107 Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J, Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice. Hum Mol Genet. 2022 Oct 10;31(20):3504-3520 |
1* | J:72635 Kim JK, Huh SO, Choi H, Lee KS, Shin D, Lee C, Nam JS, Kim H, Chung H, Lee HW, Park SD, Seong RH, Srg3, a mouse homolog of yeast swi3, is essential for early embryogenesis and involved in brain development. Mol Cell Biol. 2001 Nov;21(22):7787-95 |
2 | J:206588 Mardaryev AN, Gdula MR, Yarker JL, Emelianov VN, Poterlowicz K, Sharov AA, Sharova TY, Scarpa JA, Chambon P, Botchkarev VA, Fessing MY, p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells. Development. 2014 Jan;141(1):101-11 |
3 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
2* | J:16411 Randazzo FM, Khavari P, Crabtree G, Tamkun J, Rossant J, brg1: a putative murine homologue of the Drosophila brahma gene, a homeotic gene regulator. Dev Biol. 1994 Jan;161(1):229-42 |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
1* | J:236406 Takada Y, Fukuda A, Chiba T, Seno H, Brg1 plays an essential role in development and homeostasis of the duodenum through regulation of Notch signaling. Development. 2016 Oct 1;143(19):3532-3539 |
1* | J:316179 Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y, An epigenetic circuit controls neurogenic programs during neocortex development. Development. 2021;148:dev199772 |
1 | J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26 |
Smarca5 SNF2 related chromatin remodeling ATPase 5 (Synonyms: 4933427E24Rik, D030040M08Rik, D330027N15Rik, MommeD4, Snf2h) | |
Results | Reference |
1 | J:235665 He S, Limi S, McGreal RS, Xie Q, Brennan LA, Kantorow WL, Kokavec J, Majumdar R, Hou H Jr, Edelmann W, Liu W, Ashery-Padan R, Zavadil J, Kantorow M, Skoultchi AI, Stopka T, Cvekl A, Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation. Development. 2016 Jun 1;143(11):1937-47 |
Smarcb1 SWI/SNF related BAF chromatin remodeling complex subunit B1 (Synonyms: Baf47, Ini1, integrase interactor 1, Snf5, SNF5/INI1) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
Smarcc1 SWI/SNF related BAF chromatin remodeling complex subunit C1 (Synonyms: BAF155, msp3, SRG3) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
1* | J:72635 Kim JK, Huh SO, Choi H, Lee KS, Shin D, Lee C, Nam JS, Kim H, Chung H, Lee HW, Park SD, Seong RH, Srg3, a mouse homolog of yeast swi3, is essential for early embryogenesis and involved in brain development. Mol Cell Biol. 2001 Nov;21(22):7787-95 |
1 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1* | J:316179 Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y, An epigenetic circuit controls neurogenic programs during neocortex development. Development. 2021;148:dev199772 |
Smarcc2 SWI/SNF related BAF chromatin remodeling complex subunit C2 (Synonyms: 5930405J04Rik) | |
Results | Reference |
1* | J:184001 Ahmed M, Xu J, Xu PX, EYA1 and SIX1 drive the neuronal developmental program in cooperation with the SWI/SNF chromatin-remodeling complex and SOX2 in the mammalian inner ear. Development. 2012 Jun;139(11):1965-77 |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
1 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
2 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
1 | J:197141 Tuoc TC, Boretius S, Sansom SN, Pitulescu ME, Frahm J, Livesey FJ, Stoykova A, Chromatin Regulation by BAF170 Controls Cerebral Cortical Size and Thickness. Dev Cell. 2013 May 13;25(3):256-69 |
1* | J:316179 Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y, An epigenetic circuit controls neurogenic programs during neocortex development. Development. 2021;148:dev199772 |
Smarcd1 SWI/SNF related BAF chromatin remodeling complex subunit D1 (Synonyms: Baf60a, D15Kz1) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
Smarcd2 SWI/SNF related BAF chromatin remodeling complex subunit D2 (Synonyms: Baf60b) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
1 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
Smarcd3 SWI/SNF related BAF chromatin remodeling complex subunit D3 (Synonyms: 1500001J14Rik, 2210409C08Rik, BAF60C) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
1* | J:89493 Debril MB, Gelman L, Fayard E, Annicotte JS, Rocchi S, Auwerx J, Transcription factors and nuclear receptors interact with the SWI/SNF complex through the BAF60c subunit. J Biol Chem. 2004 Apr 16;279(16):16677-86 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1* | J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903 |
Smarce1 SWI/SNF related BAF chromatin remodeling complex subunit E1 (Synonyms: 2810417B20Rik, 5830412H02Rik, 9030408N19Rik, BAF57) | |
Results | Reference |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
1 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1* | J:316179 Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y, An epigenetic circuit controls neurogenic programs during neocortex development. Development. 2021;148:dev199772 |
Smc1b structural maintenance of chromosomes 1B (Synonyms: SMC1beta, Smc1l2) | |
Results | Reference |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
Smc3 structural maintenance of chromosomes 3 (Synonyms: Bamacan, Cspg6, Mmip1, SmcD) | |
Results | Reference |
1 | J:211663 Fukuda T, Fukuda N, Agostinho A, Hernandez-Hernandez A, Kouznetsova A, Hoog C, STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. EMBO J. 2014 Jun 2;33(11):1243-55 |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
1* | J:354443 Zhang B, Zhu Y, Zhang Z, Wu F, Ma X, Sheng W, Dai R, Guo Z, Yan W, Hao L, Huang G, Ma D, Hao B, Ma J, SMC3 contributes to heart development by regulating super-enhancer associated genes. Exp Mol Med. 2024 Aug;56(8):1826-1842 |
Smc5 structural maintenance of chromosomes 5 (Synonyms: MGC:7569, Smc5l1) | |
Results | Reference |
1 | J:299451 Atkins A, Xu MJ, Li M, Rogers NP, Pryzhkova MV, Jordan PW, SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. Elife. 2020 Nov 17;9:e61171 |
Smc6 structural maintenance of chromosomes 6 (Synonyms: 2810489L22Rik, 3830418C19Rik, Smc6l1) | |
Results | Reference |
1 | J:299451 Atkins A, Xu MJ, Li M, Rogers NP, Pryzhkova MV, Jordan PW, SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. Elife. 2020 Nov 17;9:e61171 |
Smgc submandibular gland protein C (Synonyms: 2310010P21Rik, DXImx49e, Sfc21) | |
Results | Reference |
2 | J:341713 Aure MH, Symonds JM, Villapudua CU, Dodge JT, Werner S, Knosp WM, Hoffman MP, FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation. Nat Commun. 2023 Oct 14;14(1):6485 |
1* | J:218202 Mellas RE, Kim H, Osinski J, Sadibasic S, Gronostajski RM, Cho M, Baker OJ, NFIB Regulates Embryonic Development of Submandibular Glands. J Dent Res. 2015 Feb;94(2):312-9 |
Smo smoothened, frizzled class receptor (Synonyms: E130215L21Rik) | |
Results | Reference |
1 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1 | J:144348 Ohazama A, Johnson EB, Ota MS, Choi HJ, Porntaveetus T, Oommen S, Itoh N, Eto K, Gritli-Linde A, Herz J, Sharpe PT, Lrp4 modulates extracellular integration of cell signaling pathways in development. PLoS One. 2008;3(12):e4092 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1 | J:159209 Tornqvist G, Sandberg A, Hagglund AC, Carlsson L, Cyclic expression of lhx2 regulates hair formation. PLoS Genet. 2010;6(4):e1000904 |
Smoc1 SPARC related modular calcium binding 1 (Synonyms: 2600002F22Rik, SPARC-related protein, SRG) | |
Results | Reference |
1 | J:226941 Akerberg BN, Sarangam ML, Stankunas K, Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Dev Biol. 2015 Nov 1;407(1):158-72 |
2 | J:144899 Gersdorff N, Muller M, Schall A, Miosge N, Secreted modular calcium-binding protein-1 localization during mouse embryogenesis. Histochem Cell Biol. 2006 Dec;126(6):705-12 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Smoc2 SPARC related modular calcium binding 2 (Synonyms: 1700056C05Rik, 5430426J21Rik, Smoc2l) | |
Results | Reference |
1* | J:191534 Bloch-Zupan A, Jamet X, Etard C, Laugel V, Muller J, Geoffroy V, Strauss JP, Pelletier V, Marion V, Poch O, Strahle U, Stoetzel C, Dollfus H, Homozygosity mapping and candidate prioritization identify mutations, missed by whole-exome sequencing, in SMOC2, causing major dental developmental defects. Am J Hum Genet. 2011 Dec 9;89(6):773-81 |
1 | J:359797 Coren L, Zaffryar-Eilot S, Odeh A, Kaganovsky A, Hasson P, Fibroblast diversification is an embryonic process dependent on muscle contraction. Cell Rep. 2024 Dec 4;43(12):115034 |
1 | J:330742 Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM, In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022 Oct 17;132(20):e156955 |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Smpd1 sphingomyelin phosphodiesterase 1, acid lysosomal (Synonyms: acid sphingomyelinase, ASM, aSMase, A-SMase, Zn-SMase) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Smpd2 sphingomyelin phosphodiesterase 2, neutral (Synonyms: nSMase) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Smpd3 sphingomyelin phosphodiesterase 3, neutral (Synonyms: 4631433G07Rik, fro, neutral sphingomyelinase II, Nsm2, nSMase2) | |
Results | Reference |
1 | J:327415 Jing J, Feng J, Yuan Y, Guo T, Lei J, Pei F, Ho TV, Chai Y, Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis. Nat Commun. 2022 Aug 16;13(1):4803 |
1 | J:176975 Khavandgar Z, Poirier C, Clarke CJ, Li J, Wang N, McKee MD, Hannun YA, Murshed M, A cell-autonomous requirement for neutral sphingomyelinase 2 in bone mineralization. J Cell Biol. 2011 Jul 25;194(2):277-89 |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
Smtn smoothelin | |
Results | Reference |
1 | J:361958 Straube P, Beckers A, Jany UWH, Bergmann F, Ludtke TH, Rudat C, Trowe MO, Peters I, Klopf MG, Mamo TM, Kispert A, Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter. Development. 2025 Feb 1;152(3) |
Smtnl1 smoothelin-like 1 (Synonyms: 1110030K22Rik, Chasm) | |
Results | Reference |
1* | J:136573 Wooldridge AA, Fortner CN, Lontay B, Akimoto T, Neppl RL, Facemire C, Datto MB, Kwon A, McCook E, Li P, Wang S, Thresher RJ, Miller SE, Perriard JC, Gavin TP, Hickner RC, Coffman TM, Somlyo AV, Yan Z, Haystead TA, Deletion of the protein kinase A/protein kinase G target SMTNL1 promotes an exercise-adapted phenotype in vascular smooth muscle. J Biol Chem. 2008 Apr 25;283(17):11850-9 |
Smurf2 SMAD specific E3 ubiquitin protein ligase 2 (Synonyms: 2810411E22Rik) | |
Results | Reference |
3 | J:196581 Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G, The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-beta signaling. Dev Biol. 2013 May 15;377(2):415-27 |
1 | J:156253 Tateossian H, Hardisty-Hughes RE, Morse S, Romero MR, Hilton H, Dean C, Brown SD, Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant. Pathogenetics. 2009;2(1):5 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
Smyd1 SET and MYND domain containing 1 (Synonyms: 4632404M21Rik, Bop) | |
Results | Reference |
1 | J:332132 Cattaneo P, Hayes MGB, Baumgarten N, Hecker D, Peruzzo S, Aslan GS, Kunderfranco P, Larcher V, Zhang L, Contu R, Fonseca G, Spinozzi S, Chen J, Condorelli G, Dimmeler S, Schulz MH, Heinz S, Guimaraes-Camboa N, Evans SM, DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal. Nat Commun. 2022 Dec 2;13(1):7444 |
1* | J:158898 Diehl F, Brown MA, van Amerongen MJ, Novoyatleva T, Wietelmann A, Harriss J, Ferrazzi F, Bottger T, Harvey RP, Tucker PW, Engel FB, Cardiac deletion of Smyd2 is dispensable for mouse heart development. PLoS One. 2010;5(3):e9748 |
2 | J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97 |
Smyd2 SET and MYND domain containing 2 (Synonyms: 1110020E07Rik, KMT3C, Zmynd14) | |
Results | Reference |
1* | J:158898 Diehl F, Brown MA, van Amerongen MJ, Novoyatleva T, Wietelmann A, Harriss J, Ferrazzi F, Bottger T, Harvey RP, Tucker PW, Engel FB, Cardiac deletion of Smyd2 is dispensable for mouse heart development. PLoS One. 2010;5(3):e9748 |
Smyd5 SET and MYND domain containing 5 (Synonyms: MGC:29044, NN8-4AG, Rai15, Rrg1) | |
Results | Reference |
1* | J:158898 Diehl F, Brown MA, van Amerongen MJ, Novoyatleva T, Wietelmann A, Harriss J, Ferrazzi F, Bottger T, Harvey RP, Tucker PW, Engel FB, Cardiac deletion of Smyd2 is dispensable for mouse heart development. PLoS One. 2010;5(3):e9748 |
Snai1 snail family zinc finger 1 (Synonyms: Sna, Sna1, Snail, Snail1) | |
Results | Reference |
1 | J:239479 Arora H, Boulberdaa M, Qureshi R, Bitirim V, Messadeq N, Dolle P, Nebigil CG, Prokineticin receptor 1 is required for mesenchymal-epithelial transition in kidney development. FASEB J. 2016 Aug;30(8):2733-40 |
1 | J:192176 Casanova JC, Travisano S, de la Pompa JL, Epithelial-to-mesenchymal transition in epicardium is independent of snail1. Genesis. 2013 Jan;51(1):32-40 |
3* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:146483 de Frutos CA, Dacquin R, Vega S, Jurdic P, Machuca-Gayet I, Nieto MA, Snail1 controls bone mass by regulating Runx2 and VDR expression during osteoblast differentiation. EMBO J. 2009 Mar 18;28(6):686-96 |
1 | J:128902 de Frutos CA, Vega S, Manzanares M, Flores JM, Huertas H, Martinez-Frias ML, Nieto MA, Snail1 is a transcriptional effector of FGFR3 signaling during chondrogenesis and achondroplasias. Dev Cell. 2007 Dec;13(6):872-83 |
1 | J:168537 Gouzi M, Kim YH, Katsumoto K, Johansson K, Grapin-Botton A, Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development. Dev Dyn. 2011 Mar;240(3):589-604 |
1 | J:221041 Horvay K, Jarde T, Casagranda F, Perreau VM, Haigh K, Nefzger CM, Akhtar R, Gridley T, Berx G, Haigh JJ, Barker N, Polo JM, Hime GR, Abud HE, Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium. EMBO J. 2015 May 12;34(10):1319-35 |
1 | J:97750 Jamora C, Lee P, Kocieniewski P, Azhar M, Hosokawa R, Chai Y, Fuchs E, A signaling pathway involving TGF-beta2 and snail in hair follicle morphogenesis. PLoS Biol. 2005 Jan;3(1):e11 |
1 | J:254094 Jing X, Gao Y, Xiao S, Qin Q, Wei X, Yan Y, Wu L, Deng S, Du J, Liu Y, She Q, Hypoxia induced the differentiation of Tbx18-positive epicardial cells to CoSMCs. Sci Rep. 2016 Jul 26;6:30468 |
1* | J:87413 Martinez-Alvarez C, Blanco MJ, Perez R, Rabadan MA, Aparicio M, Resel E, Martinez T, Nieto MA, Snail family members and cell survival in physiological and pathological cleft palates. Dev Biol. 2004 Jan 1;265(1):207-18 |
1 | J:166573 Martinez-Estrada OM, Lettice LA, Essafi A, Guadix JA, Slight J, Velecela V, Hall E, Reichmann J, Devenney PS, Hohenstein P, Hosen N, Hill RE, Munoz-Chapuli R, Hastie ND, Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin. Nat Genet. 2010 Jan;42(1):89-93 |
1 | J:100235 Rice R, Thesleff I, Rice DP, Regulation of Twist, Snail, and Id1 is conserved between the developing murine palate and tooth. Dev Dyn. 2005 Sep;234(1):28-35 |
1* | J:3684 Smith DE, Franco del Amo F, Gridley T, Isolation of Sna, a mouse gene homologous to the Drosophila genes snail and escargot: its expression pattern suggests multiple roles during postimplantation development [published erratum appears in Development 1993 Mar;117(3):preceding table of contents]. Development. 1992 Dec;116(4):1033-9 |
1 | J:208115 Zander MA, Burns SE, Yang G, Kaplan DR, Miller FD, Snail coordinately regulates downstream pathways to control multiple aspects of Mammalian neural precursor development. J Neurosci. 2014 Apr 9;34(15):5164-75 |
Snai2 snail family zinc finger 2 (Synonyms: Slug, Slugh, Snail2) | |
Results | Reference |
1 | J:192176 Casanova JC, Travisano S, de la Pompa JL, Epithelial-to-mesenchymal transition in epicardium is independent of snail1. Genesis. 2013 Jan;51(1):32-40 |
4* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:168537 Gouzi M, Kim YH, Katsumoto K, Johansson K, Grapin-Botton A, Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development. Dev Dyn. 2011 Mar;240(3):589-604 |
1 | J:221041 Horvay K, Jarde T, Casagranda F, Perreau VM, Haigh K, Nefzger CM, Akhtar R, Gridley T, Berx G, Haigh JJ, Barker N, Polo JM, Hime GR, Abud HE, Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium. EMBO J. 2015 May 12;34(10):1319-35 |
1 | J:254094 Jing X, Gao Y, Xiao S, Qin Q, Wei X, Yan Y, Wu L, Deng S, Du J, Liu Y, She Q, Hypoxia induced the differentiation of Tbx18-positive epicardial cells to CoSMCs. Sci Rep. 2016 Jul 26;6:30468 |
1 | J:335167 Lu P, Wu B, Wang Y, Russell M, Liu Y, Bernard DJ, Zheng D, Zhou B, Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis. Dev Cell. 2023 Mar 29; |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
1* | J:82525 Oram KF, Carver EA, Gridley T, Slug expression during organogenesis in mice. Anat Rec A Discov Mol Cell Evol Biol. 2003 Mar;271(1):189-91 |
1* | J:341382 Wu B, Wu B, Benkaci S, Shi L, Lu P, Park T, Morrow BE, Wang Y, Zhou B, Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development. J Am Heart Assoc. 2023 Sep 19;12(18):e029683 |
Snai3 snail family zinc finger 3 (Synonyms: Smuc, Snail-related gene from muscle cells, Zfp293) | |
Results | Reference |
1 | J:168537 Gouzi M, Kim YH, Katsumoto K, Johansson K, Grapin-Botton A, Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development. Dev Dyn. 2011 Mar;240(3):589-604 |
Snap25 synaptosomal-associated protein 25 (Synonyms: Bdr, GENA 70, SNAP-25, sp) | |
Results | Reference |
1* | J:335231 Bustamante-Barrientos FA, Mendez-Ruette M, Molina L, Koning T, Ehrenfeld P, Gonzalez CB, Wyneken U, Henzi R, Batiz LF, Alpha-SNAP (M105I) mutation promotes neuronal differentiation of neural stem/progenitor cells through overactivation of AMPK. Front Cell Dev Biol. 2023;11:1061777 |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1* | J:281311 Nakano Y, Wiechert S, Banfi B, Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8 |
1 | J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12) |
1 | J:154587 Niquille M, Garel S, Mann F, Hornung JP, Otsmane B, Chevalley S, Parras C, Guillemot F, Gaspar P, Yanagawa Y, Lebrand C, Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C. PLoS Biol. 2009 Oct;7(10):e1000230 |
1 | J:74020 Soriano E, Del Rio JA, Martinez A, Super H, Organization of the embryonic and early postnatal murine hippocampus. I. Immunocytochemical characterization of neuronal populations in the subplate and marginal zone. J Comp Neurol. 1994 Apr 22;342(4):571-95 |
1 | J:201069 Stubbusch J, Narasimhan P, Huber K, Unsicker K, Rohrer H, Ernsberger U, Synaptic protein and pan-neuronal gene expression and their regulation by Dicer-dependent mechanisms differ between neurons and neuroendocrine cells. Neural Dev. 2013 Aug 20;8(1):16 |
1 | J:64148 Vannucchi MG, Faussone-Pellegrini MS, Synapse formation during neuron differentiation: An in situ study of the myenteric plexus during murine embryonic life. J Comp Neurol. 2000 Sep 25;425(3):369-81 |
Snap91 synaptosomal-associated protein 91 (Synonyms: 91kDa, AP180, F1-20, mKIAA0656) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Snca synuclein, alpha (Synonyms: alpha-Syn, alphaSYN, alpha-synuclein) | |
Results | Reference |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
1* | J:159509 Zhong SC, Luo X, Chen XS, Cai QY, Liu J, Chen XH, Yao ZX, Expression and subcellular location of alpha-synuclein during mouse-embryonic development. Cell Mol Neurobiol. 2010 Apr;30(3):469-82 |
Sncg synuclein, gamma (Synonyms: C79089, persyn) | |
Results | Reference |
2* | J:350259 Fernandez-Nogales M, Lopez-Cascales MT, Murcia-Belmonte V, Escalante A, Fernandez-Albert J, Munoz-Viana R, Barco A, Herrera E, Multiomic Analysis of Neurons with Divergent Projection Patterns Identifies Novel Regulators of Axon Pathfinding. Adv Sci (Weinh). 2022 Oct;9(29):e2200615 |
1 | J:249145 Goetz JJ, Laboissonniere LA, Wester AK, Lynch MR, Trimarchi JM, Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression. PLoS One. 2016;11(3):e0150878 |
1 | J:223559 Goetz JJ, Martin GM, Chowdhury R, Trimarchi JM, Onecut1 and Onecut2 play critical roles in the development of the mouse retina. PLoS One. 2014;9(10):e110194 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Snhg1 small nucleolar RNA host gene 1 | |
Results | Reference |
1 | J:312381 Li M, Zheng H, Han Y, Chen Y, Li B, Chen G, Chen X, Huang S, He X, Wei G, Xu T, Feng X, Liao W, Liao Y, Chen Y, Bin J, LncRNA Snhg1-driven self-reinforcing regulatory network promoted cardiac regeneration and repair after myocardial infarction. Theranostics. 2021;11(19):9397-9414 |
Snhg5 small nucleolar RNA host gene 5 (Synonyms: 2810026P18Rik, mU50HG-b) | |
Results | Reference |
1* | J:212084 Herriges MJ, Swarr DT, Morley MP, Rathi KS, Peng T, Stewart KM, Morrisey EE, Long noncoding RNAs are spatially correlated with transcription factors and regulate lung development. Genes Dev. 2014 Jun 15;28(12):1363-79 |
Snhg11 small nucleolar RNA host gene 11 (Synonyms: A930034L06Rik, E130013N09Rik) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Snorc secondary ossification center associated regulator of chondrocyte maturation (Synonyms: 3110079O15Rik, Snorc) | |
Results | Reference |
2* | J:174146 Heinonen J, Taipaleenmaki H, Roering P, Takatalo M, Harkness L, Sandholm J, Uusitalo-Jarvinen H, Kassem M, Kiviranta I, Laitala-Leinonen T, Saamanen AM, Snorc is a novel cartilage specific small membrane proteoglycan expressed in differentiating and articular chondrocytes. Osteoarthritis Cartilage. 2011 Aug;19(8):1026-35 |
1 | J:250431 Heinonen J, Zhang FP, Surmann-Schmitt C, Honkala S, Stock M, Poutanen M, Saamanen AM, Defects in chondrocyte maturation and secondary ossification in mouse knee joint epiphyses due to Snorc deficiency. Osteoarthritis Cartilage. 2017 Jul;25(7):1132-1142 |
Snrk SNF related kinase (Synonyms: 2010012F07Rik, MGC:28970, mKIAA0096, SNRK) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Snrpe small nuclear ribonucleoprotein E | |
Results | Reference |
1 | J:182350 Zanucco E, Gotz R, Potapenko T, Carraretto I, Ceteci S, Ceteci F, Seeger W, Savai R, Rapp UR, Expression of B-RAF V600E in type II pneumocytes causes abnormalities in alveolar formation, airspace enlargement and tumor formation in mice. PLoS One. 2011;6(12):e29093 |
Snrpn small nuclear ribonucleoprotein N (Synonyms: 2410045I01Rik, MGC:18604, MGC:30325, Peg4, Pwcr1) | |
Results | Reference |
1* | J:267655 Marjonen H, Toivonen M, Lahti L, Kaminen-Ahola N, Early prenatal alcohol exposure alters imprinted gene expression in placenta and embryo in a mouse model. PLoS One. 2018;13(5):e0197461 |
1 | J:30428 Szabo PE, Mann JR, Allele-specific expression and total expression levels of imprinted genes during early mouse development: implications for imprinting mechanisms. Genes Dev. 1995 Dec 15;9(24):3097-108 |
Sntn sentan, cilia apical structure protein (Synonyms: A430083B19Rik) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Snx5 sorting nexin 5 (Synonyms: 0910001N05Rik, 1810032P22Rik, D2Ertd52e) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Snx10 sorting nexin 10 (Synonyms: 2410004M09Rik) | |
Results | Reference |
1* | J:183128 Zhu CH, Morse LR, Battaglino RA, SNX10 is required for osteoclast formation and resorption activity. J Cell Biochem. 2012 May;113(5):1608-15 |
Snx12 sorting nexin 12 (Synonyms: 2610001F05Rik) | |
Results | Reference |
2* | J:181157 Mizutani R, Nakamura K, Kato N, Aizawa K, Miyamoto Y, Torii T, Yamauchi J, Tanoue A, Expression of sorting nexin 12 is regulated in developing cerebral cortical neurons. J Neurosci Res. 2012 Apr;90(4):721-31 |
Snx14 sorting nexin 14 (Synonyms: C330035N22Rik, YR-14) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Snx15 sorting nexin 15 (Synonyms: 1500032B08Rik, E130013C21Rik) | |
Results | Reference |
1* | J:315121 Feng T, Niu M, Ji C, Gao Y, Wen J, Bu G, Xu H, Zhang YW, SNX15 Regulates Cell Surface Recycling of APP and Abeta Generation. Mol Neurobiol. 2016 Aug;53(6):3690-3701 |
Snx31 sorting nexin 31 (Synonyms: 4631426E05Rik) | |
Results | Reference |
1* | J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903 |
Socs1 suppressor of cytokine signaling 1 (Synonyms: Cish1, Cish7, JAB, JAK2-binding protein, JAK-binding protein, SOCS-1, SSI-1, STAT-induced STAT inhibitor 1) | |
Results | Reference |
1* | J:257927 Fairchild CL, Hino K, Han JS, Miltner AM, Peinado Allina G, Brown CE, Burns ME, La Torre A, Simo S, RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3):dev155283 |
1 | J:62883 Polizzotto MN, Bartlett PF, Turnley AM, Expression of 'suppressor of cytokine signalling' (SOCS) genes in the developing and adult mouse nervous system. J Comp Neurol. 2000 Jul 24;423(2):348-58 |
Socs2 suppressor of cytokine signaling 2 (Synonyms: CIS2, Cish2, cytokine-inducible SH2 protein 2, D130043N08Rik, JAB, SOCS-2, SSI-2, STAT-induced STAT inhibitor 2) | |
Results | Reference |
1* | J:257927 Fairchild CL, Hino K, Han JS, Miltner AM, Peinado Allina G, Brown CE, Burns ME, La Torre A, Simo S, RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3):dev155283 |
1 | J:62883 Polizzotto MN, Bartlett PF, Turnley AM, Expression of 'suppressor of cytokine signalling' (SOCS) genes in the developing and adult mouse nervous system. J Comp Neurol. 2000 Jul 24;423(2):348-58 |
Socs3 suppressor of cytokine signaling 3 (Synonyms: CIS3, Cish3, cytokine-inducible SH2 protein 3, E2a-Pbx1 target gene in fibroblasts 10, EF-10, SOCS-3, SSI-3, STAT-induced STAT inhibitor 3) | |
Results | Reference |
1* | J:257927 Fairchild CL, Hino K, Han JS, Miltner AM, Peinado Allina G, Brown CE, Burns ME, La Torre A, Simo S, RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3):dev155283 |
1 | J:62883 Polizzotto MN, Bartlett PF, Turnley AM, Expression of 'suppressor of cytokine signalling' (SOCS) genes in the developing and adult mouse nervous system. J Comp Neurol. 2000 Jul 24;423(2):348-58 |
Socs4 suppressor of cytokine signaling 4 (Synonyms: 3110032M18Rik, A730004F22Rik, Socs7) | |
Results | Reference |
1* | J:257927 Fairchild CL, Hino K, Han JS, Miltner AM, Peinado Allina G, Brown CE, Burns ME, La Torre A, Simo S, RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3):dev155283 |
Socs5 suppressor of cytokine signaling 5 (Synonyms: 1810018L08Rik, Cish5, SOCS-5) | |
Results | Reference |
1* | J:257927 Fairchild CL, Hino K, Han JS, Miltner AM, Peinado Allina G, Brown CE, Burns ME, La Torre A, Simo S, RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3):dev155283 |
Socs6 suppressor of cytokine signaling 6 (Synonyms: 1500012M23Rik, 5830401B18Rik, CIS4, Cish4, HSPC060, Socs4, SOCS-4, SOCS-6, SSI4, STAI4, STAT4, STATI4) | |
Results | Reference |
1* | J:257927 Fairchild CL, Hino K, Han JS, Miltner AM, Peinado Allina G, Brown CE, Burns ME, La Torre A, Simo S, RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3):dev155283 |
Socs7 suppressor of cytokine signaling 7 (Synonyms: 2310063P06Rik, Nap4) | |
Results | Reference |
1* | J:257927 Fairchild CL, Hino K, Han JS, Miltner AM, Peinado Allina G, Brown CE, Burns ME, La Torre A, Simo S, RBX2 maintains final retinal cell position in a DAB1-dependent and -independent fashion. Development. 2018 Feb 2;145(3):dev155283 |
1 | J:205551 Simo S, Cooper JA, Rbx2 regulates neuronal migration through different cullin 5-RING ligase adaptors. Dev Cell. 2013 Nov 25;27(4):399-411 |
Sod1 superoxide dismutase 1, soluble (Synonyms: B430204E11Rik, Cu(2+)-Zn2+ superoxide dismutase, Cu/Zn-SOD, CuZnSOD, Ipo-1, Ipo1, Sod-1, SODC) | |
Results | Reference |
1* | J:17746 de Haan JB, Tymms MJ, Cristiano F, Kola I, Expression of copper/zinc superoxide dismutase and glutathione peroxidase in organs of developing mouse embryos, fetuses, and neonates. Pediatr Res. 1994 Feb;35(2):188-96 |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
2* | J:127407 Yon JM, Baek IJ, Lee SR, Jin Y, Kim MR, Nahm SS, Kim JS, Ahn B, Lee BJ, Yun YW, Nam SY, The spatio-temporal expression pattern of cytoplasmic Cu/Zn superoxide dismutase (SOD1) mRNA during mouse embryogenesis. J Mol Histol. 2008 Feb;39(1):95-103 |
2* | J:141032 Yon JM, Baek IJ, Lee SR, Kim MR, Lee BJ, Yun YW, Nam SY, Immunohistochemical identification and quantitative analysis of cytoplasmic Cu/Zn superoxide dismutase in mouse organogenesis. J Vet Sci. 2008 Sep;9(3):233-40 |
Sod2 superoxide dismutase 2, mitochondrial (Synonyms: manganese SOD, manganese superoxide dismutase, MGC:6144, MnSOD, Sod-2) | |
Results | Reference |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
4* | J:174063 Yon JM, Baek IJ, Lee BJ, Yun YW, Nam SY, Dynamic expression of manganese superoxide dismutase during mouse embryonic organogenesis. Int J Dev Biol. 2011;55(3):327-34 |
Sod3 superoxide dismutase 3, extracellular (Synonyms: EC-SOD, MGC:13799) | |
Results | Reference |
3* | J:170398 Kim MR, Yon JM, Lee SR, Baek IJ, Kim JS, Hong JT, Lee BJ, Yun YW, Nam SY, Expression profiles of extracellular superoxide dismutase during mouse organogenesis. Gene Expr Patterns. 2011 Mar-Apr;11(3-4):207-15 |
1* | J:221341 Lun MP, Johnson MB, Broadbelt KG, Watanabe M, Kang YJ, Chau KF, Springel MW, Malesz A, Sousa AM, Pletikos M, Adelita T, Calicchio ML, Zhang Y, Holtzman MJ, Lidov HG, Sestan N, Steen H, Monuki ES, Lehtinen MK, Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production. J Neurosci. 2015 Mar 25;35(12):4903-16 |
Sohlh1 spermatogenesis and oogenesis specific basic helix-loop-helix 1 (Synonyms: LOC227631, NOHLH) | |
Results | Reference |
2 | J:244395 Shin YH, Ren Y, Suzuki H, Golnoski KJ, Ahn HW, Mico V, Rajkovic A, Transcription factors SOHLH1 and SOHLH2 coordinate oocyte differentiation without affecting meiosis I. J Clin Invest. 2017 Jun 01;127(6):2106-2117 |
1 | J:297097 Sorrenti M, Klinger FG, Iona S, Rossi V, Marcozzi S, DE Felici M, Expression and possible roles of extracellular signal-related kinases 1-2 (ERK1-2) in mouse primordial germ cell development. J Reprod Dev. 2020 Oct 13;66(5):399-409 |
1* | J:143535 Toyoda S, Miyazaki T, Miyazaki S, Yoshimura T, Yamamoto M, Tashiro F, Yamato E, Miyazaki J, Sohlh2 affects differentiation of KIT positive oocytes and spermatogonia. Dev Biol. 2009 Jan 1;325(1):238-48 |
Sohlh2 spermatogenesis and oogenesis specific basic helix-loop-helix 2 (Synonyms: 4933406N12Rik) | |
Results | Reference |
1* | J:191898 Moreno DL, Salazar Z, Betancourt M, Casas E, Ducolomb Y, Gonzalez C, Bonilla E, Sebox plays an important role during the early mouse oogenesis in vitro. Zygote. 2012 Jul 18;:1-5 |
1 | J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34 |
1 | J:244395 Shin YH, Ren Y, Suzuki H, Golnoski KJ, Ahn HW, Mico V, Rajkovic A, Transcription factors SOHLH1 and SOHLH2 coordinate oocyte differentiation without affecting meiosis I. J Clin Invest. 2017 Jun 01;127(6):2106-2117 |
1 | J:297097 Sorrenti M, Klinger FG, Iona S, Rossi V, Marcozzi S, DE Felici M, Expression and possible roles of extracellular signal-related kinases 1-2 (ERK1-2) in mouse primordial germ cell development. J Reprod Dev. 2020 Oct 13;66(5):399-409 |
1* | J:143535 Toyoda S, Miyazaki T, Miyazaki S, Yoshimura T, Yamamoto M, Tashiro F, Yamato E, Miyazaki J, Sohlh2 affects differentiation of KIT positive oocytes and spermatogonia. Dev Biol. 2009 Jan 1;325(1):238-48 |
1 | J:362758 Zhang L, Li Y, Hu Y, Chen M, Cen C, Chen M, Lin L, Zhou J, Wang M, Cui X, Tang F, Gao F, Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression. FASEB J. 2022 Feb;36(2):e22131 |
Sorbs1 sorbin and SH3 domain containing 1 (Synonyms: 2310065E01Rik, 9530001P15Rik, CAP, c-Cbl-associated protein, mKIAA1296, Ponsin, Sh3d5) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Sorcs1 sortilin-related VPS10 domain containing receptor 1 | |
Results | Reference |
1* | J:74098 Hermey G, Schaller HC, Hermans-Borgmeyer I, Transient expression of SorCS in developing telencephalic and mesencephalic structures of the mouse. Neuroreport. 2001 Jan 22;12(1):29-32 |
Sorcs2 sortilin-related VPS10 domain containing receptor 2 (Synonyms: mKIAA1329, VPS10 domain receptor protein) | |
Results | Reference |
1* | J:67268 Rezgaoui M, Hermey G, Riedel IB, Hampe W, Schaller HC, Hermans-Borgmeyer I, Identification of SorCS2, a novel member of the VPS10 domain containing receptor family, prominently expressed in the developing mouse brain. Mech Dev. 2001 Feb;100(2):335-8 |
Sorcs3 sortilin-related VPS10 domain containing receptor 3 (Synonyms: 6330404A12Rik) | |
Results | Reference |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Sorl1 sortilin-related receptor, LDLR class A repeats-containing (Synonyms: 2900010L19Rik, LR11, mSorLA, Sorla) | |
Results | Reference |
1* | J:46143 Hermans-Borgmeyer I, Hampe W, Schinke B, Methner A, Nykjaer A, Susens U, Fenger U, Herbarth B, Schaller HC, Unique expression pattern of a novel mosaic receptor in the developing cerebral cortex. Mech Dev. 1998 Jan;70(1-2):65-76 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Sort1 sortilin 1 (Synonyms: 2900053A11Rik, neurotensin receptor 3, Ntr3, Ntsr3, sortilin) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:53414 Hermans-Borgmeyer I, Hermey G, Nykjaer A, Schaller C, Expression of the 100-kDa neurotensin receptor sortilin during mouse embryonal development. Brain Res Mol Brain Res. 1999 Mar 5;65(2):216-9 |
Sost sclerostin (Synonyms: 5430411E23Rik) | |
Results | Reference |
1 | J:128100 Ellies DL, Viviano B, McCarthy J, Rey JP, Itasaki N, Saunders S, Krumlauf R, Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity. J Bone Miner Res. 2006 Nov;21(11):1738-49 |
1 | J:143588 Kamiya N, Ye L, Kobayashi T, Mochida Y, Yamauchi M, Kronenberg HM, Feng JQ, Mishina Y, BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development. 2008 Nov;135(22):3801-11 |
1 | J:294900 Koide M, Yamashita T, Murakami K, Uehara S, Nakamura K, Nakamura M, Matsushita M, Ara T, Yasuda H, Penninger JM, Takahashi N, Udagawa N, Kobayashi Y, Sclerostin expression in trabecular bone is downregulated by osteoclasts. Sci Rep. 2020 Aug 13;10(1):13751 |
1 | J:316483 Leek CC, Soulas JM, Bhattacharya I, Ganji E, Locke RC, Smith MC, Bhavsar JD, Polson SW, Ornitz DM, Killian ML, Deletion of Fibroblast growth factor 9 globally and in skeletal muscle results in enlarged tuberosities at sites of deltoid tendon attachments. Dev Dyn. 2021 Dec;250(12):1778-1795 |
1* | J:170473 Naka T, Yokose S, Spatiotemporal expression of sclerostin in odontoblasts during embryonic mouse tooth morphogenesis. J Endod. 2011 Mar;37(3):340-5 |
1 | J:92630 Ohyama Y, Nifuji A, Maeda Y, Amagasa T, Noda M, Spaciotemporal association and bone morphogenetic protein regulation of sclerostin and osterix expression during embryonic osteogenesis. Endocrinology. 2004 Oct;145(10):4685-92 |
1* | J:307192 Yadav PS, Feng S, Cong Q, Kim H, Liu Y, Yang Y, Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118 |
Sostdc1 sclerostin domain containing 1 (Synonyms: ectodin, Sostl, USAG-1, Wise) | |
Results | Reference |
1 | J:111051 Cui CY, Hashimoto T, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9142-7 |
1 | J:128100 Ellies DL, Viviano B, McCarthy J, Rey JP, Itasaki N, Saunders S, Krumlauf R, Bone density ligand, Sclerostin, directly interacts with LRP5 but not LRP5G171V to modulate Wnt activity. J Bone Miner Res. 2006 Nov;21(11):1738-49 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1 | J:118173 Jarvinen E, Salazar-Ciudad I, Birchmeier W, Taketo MM, Jernvall J, Thesleff I, Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18627-32 |
1 | J:265947 Kawasaki M, Kawasaki K, Meguro F, Yamada A, Ishikawa R, Porntaveetus T, Blackburn J, Otsuka-Tanaka Y, Saito N, Ota MS, Sharpe PT, Kessler JA, Herz J, Cobourne MT, Maeda T, Ohazama A, Lrp4/Wise regulates palatal rugae development through Turing-type reaction-diffusion mechanisms. PLoS One. 2018;13(9):e0204126 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Sowaha sosondowah ankyrin repeat domain family member A (Synonyms: A830006N08Rik, Ankrd43) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Sox1 SRY (sex determining region Y)-box 1 (Synonyms: Sox-1) | |
Results | Reference |
1 | J:269420 Franz H, Villarreal A, Heidrich S, Videm P, Kilpert F, Mestres I, Calegari F, Backofen R, Manke T, Vogel T, DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex. Nucleic Acids Res. 2019 Jan 10;47(1):168-183 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:151537 Maeda A, Moriguchi T, Hamada M, Kusakabe M, Fujioka Y, Nakano T, Yoh K, Lim KC, Engel JD, Takahashi S, Transcription factor GATA-3 is essential for lens development. Dev Dyn. 2009 Jul 21;238(9):2280-2291 |
1 | J:357897 Renaux E, Baudouin C, Schakman O, Gay O, Martin M, Marchese D, Achouri Y, Rezsohazy R, Gofflot F, Clotman F, Arid3c identifies an uncharacterized subpopulation of V2 interneurons during embryonic spinal cord development. Front Cell Neurosci. 2024;18:1466056 |
Sox2 SRY (sex determining region Y)-box 2 (Synonyms: lcc, Sox-2, ysb) | |
Results | Reference |
1 | J:226478 Abe P, Molnar Z, Tzeng YS, Lai DM, Arnold SJ, Stumm R, Intermediate Progenitors Facilitate Intracortical Progression of Thalamocortical Axons and Interneurons through CXCL12 Chemokine Signaling. J Neurosci. 2015 Sep 23;35(38):13053-63 |
1* | J:348861 Aberle T, Walter A, Piefke S, Hillgartner S, Wust HM, Wegner M, Kuspert M, Sox10 Activity and the Timing of Schwann Cell Differentiation Are Controlled by a Tle4-Dependent Negative Feedback Loop. Int J Mol Sci. 2024 May 11;25(10) |
1* | J:181471 Ahmed M, Wong EY, Sun J, Xu J, Wang F, Xu PX, Eya1-six1 interaction is sufficient to induce hair cell fate in the cochlea by activating atoh1 expression in cooperation with sox2. Dev Cell. 2012 Feb 14;22(2):377-90 |
1 | J:299451 Atkins A, Xu MJ, Li M, Rogers NP, Pryzhkova MV, Jordan PW, SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. Elife. 2020 Nov 17;9:e61171 |
1 | J:223814 Aujla PK, Bogdanovic V, Naratadam GT, Raetzman LT, Persistent expression of activated notch in the developing hypothalamus affects survival of pituitary progenitors and alters pituitary structure. Dev Dyn. 2015 Aug;244(8):921-34 |
1 | J:305458 Bertacchi M, Romano AL, Loubat A, Tran Mau-Them F, Willems M, Faivre L, Khau van Kien P, Perrin L, Devillard F, Sorlin A, Kuentz P, Philippe C, Garde A, Neri F, Di Giaimo R, Oliviero S, Cappello S, D'Incerti L, Frassoni C, Studer M, NR2F1 regulates regional progenitor dynamics in the mouse neocortex and cortical gyrification in BBSOAS patients. EMBO J. 2020 Jul 1;39(13):e104163 |
1 | J:267642 Biggs LC, Makela OJ, Myllymaki SM, Das Roy R, Narhi K, Pispa J, Mustonen T, Mikkola ML, Hair follicle dermal condensation forms via Fgf20 primed cell cycle exit, cell motility, and aggregation. Elife. 2018 Jul 31;7:e36468 |
1 | J:316182 Blume M, Inoguchi F, Sugiyama T, Owada Y, Osumi N, Aimi Y, Taki K, Katsuyama Y, Dab1 contributes differently to the morphogenesis of the hippocampal subdivisions. Dev Growth Differ. 2017 Oct;59(8):657-673 |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1 | J:309359 Brinkmeier ML, Bando H, Camarano AC, Fujio S, Yoshimoto K, de Souza FS, Camper SA, Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. J Clin Invest. 2020 Aug 3;130(8):4501-4515 |
1 | J:282102 Canizares MA, Albors AR, Singer G, Suttie N, Gorkic M, Felts P, Storey KG, Multiple steps characterise ventricular layer attrition to form the ependymal cell lining of the adult mouse spinal cord central canal. J Anat. 2019 Oct 31; |
1 | J:300487 Chai G, Webb A, Li C, Antaki D, Lee S, Breuss MW, Lang N, Stanley V, Anzenberg P, Yang X, Marshall T, Gaffney P, Wierenga KJ, Chung BH, Tsang MH, Pais LS, Lovgren AK, VanNoy GE, Rehm HL, Mirzaa G, Leon E, Diaz J, Neumann A, Kalverda AP, Manfield IW, Parry DA, Logan CV, Johnson CA, Bonthron DT, Valleley EMA, Issa MY, Abdel-Ghafar SF, Abdel-Hamid MS, Jennings P, Zaki MS, Sheridan E, Gleeson JG, Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 Jan 20;109(2):241-256.e9 |
2 | J:202949 Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J, Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18042-51 |
1 | J:316527 Chen HH, Welling M, Bloch DB, Munoz J, Mientjes E, Chen X, Tramp C, Wu J, Yabuuchi A, Chou YF, Buecker C, Krainer A, Willemsen R, Heck AJ, Geijsen N, DAZL limits pluripotency, differentiation, and apoptosis in developing primordial germ cells. Stem Cell Reports. 2014 Nov 11;3(5):892-904 |
1 | J:317045 Cheng W, Li HL, Xi SY, Zhang XF, Zhu Y, Le Xing, Mo YX, Li MM, Kong FE, Zhu WJ, Chen XG, Cui HQ, Cao ZM, Gong YF, Tang YQ, Zhang Y, Guan XY, Ma NF, Liu M, Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma. Nat Commun. 2021 Dec 8;12(1):7142 |
1* | J:63842 Cheung M, Abu-Elmagd M, Clevers H, Scotting PJ, Roles of Sox4 in central nervous system development. Brain Res Mol Brain Res. 2000 Jun 23;79(1-2):180-91 |
1 | J:235552 Chinn GA, Hirokawa KE, Chuang TM, Urbina C, Patel F, Fong J, Funatsu N, Monuki ES, Agenesis of the Corpus Callosum Due to Defective Glial Wedge Formation in Lhx2 Mutant Mice. Cereb Cortex. 2015 Sep;25(9):2707-18 |
1 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1 | J:191082 Clavel C, Grisanti L, Zemla R, Rezza A, Barros R, Sennett R, Mazloom AR, Chung CY, Cai X, Cai CL, Pevny L, Nicolis S, Ma'ayan A, Rendl M, Sox2 in the dermal papilla niche controls hair growth by fine-tuning BMP signaling in differentiating hair shaft progenitors. Dev Cell. 2012 Nov 13;23(5):981-94 |
1 | J:226607 Clegg JM, Li Z, Molinek M, Caballero IM, Manuel MN, Price DJ, Pax6 is required intrinsically by thalamic progenitors for the normal molecular patterning of thalamic neurons but not the growth and guidance of their axons. Neural Dev. 2015;10(1):26 |
1 | J:226819 Coate TM, Spita NA, Zhang KD, Isgrig KT, Kelley MW, Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife. 2015;4 |
1 | J:167041 Cook MS, Munger SC, Nadeau JH, Capel B, Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background. Development. 2011 Jan;138(1):23-32 |
1* | J:242692 Coulthard LG, Hawksworth OA, Li R, Balachandran A, Lee JD, Sepehrband F, Kurniawan N, Jeanes A, Simmons DG, Wolvetang E, Woodruff TM, Complement C5aR1 Signaling Promotes Polarization and Proliferation of Embryonic Neural Progenitor Cells through PKCzeta. J Neurosci. 2017 May 31;37(22):5395-5407 |
1 | J:142229 Dabdoub A, Puligilla C, Jones JM, Fritzsch B, Cheah KS, Pevny LH, Kelley MW, Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea. Proc Natl Acad Sci U S A. 2008 Nov 25;105(47):18396-401 |
1* | J:202451 Del Rio T, Nishitani AM, Yu WM, Goodrich LV, In vivo analysis of lrig genes reveals redundant and independent functions in the inner ear. PLoS Genet. 2013 Sep;9(9):e1003824 |
1 | J:215675 Deng M, Luo XJ, Pan L, Yang H, Xie X, Liang G, Huang L, Hu F, Kiernan AE, Gan L, LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochlea. J Neurosci. 2014 Jul 23;34(30):10072-7 |
1 | J:152844 Driskell RR, Giangreco A, Jensen KB, Mulder KW, Watt FM, Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis. Development. 2009 Aug;136(16):2815-23 |
1* | J:330213 Ebeid M, Barnas K, Zhang H, Yaghmour A, Noreikaite G, Bjork BC, PRDM16 expression and function in mammalian cochlear development. Dev Dyn. 2022 Oct;251(10):1666-1683 |
1 | J:336102 Eenjes E, Benthem F, Boerema-de Munck A, Buscop-van Kempen M, Tibboel D, Rottier RJ, Distinct roles for SOX2 and SOX21 in differentiation, distribution and maturation of pulmonary neuroendocrine cells. Cell Mol Life Sci. 2023 Mar 3;80(3):79 |
1 | J:316977 Endale M, Ahlfeld S, Bao E, Chen X, Green J, Bess Z, Weirauch MT, Xu Y, Perl AK, Temporal, spatial, and phenotypical changes of PDGFRalpha expressing fibroblasts during late lung development. Dev Biol. 2017 May 15;425(2):161-175 |
1 | J:218288 Falcone C, Filippis C, Granzotto M, Mallamaci A, Emx2 expression levels in NSCs modulate astrogenesis rates by regulating EgfR and Fgf9. Glia. 2015 Mar;63(3):412-22 |
1 | J:132812 Fauquier T, Rizzoti K, Dattani M, Lovell-Badge R, Robinson IC, SOX2-expressing progenitor cells generate all of the major cell types in the adult mouse pituitary gland. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2907-12 |
1 | J:272744 Fawal MA, Jungas T, Kischel A, Audouard C, Iacovoni JS, Davy A, Cross Talk between One-Carbon Metabolism, Eph Signaling, and Histone Methylation Promotes Neural Stem Cell Differentiation. Cell Rep. 2018 Jun 5;23(10):2864-2873.e7 |
1 | J:311887 Filova I, Dvorakova M, Bohuslavova R, Pavlinek A, Elliott KL, Vochyanova S, Fritzsch B, Pavlinkova G, Combined Atoh1 and Neurod1 Deletion Reveals Autonomous Growth of Auditory Nerve Fibers. Mol Neurobiol. 2020 Dec;57(12):5307-5323 |
1 | J:162692 Finzsch M, Schreiner S, Kichko T, Reeh P, Tamm ER, Bosl MR, Meijer D, Wegner M, Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage. J Cell Biol. 2010 May 17;189(4):701-12 |
1 | J:205533 Gallagher D, Norman AA, Woodard CL, Yang G, Gauthier-Fisher A, Fujitani M, Vessey JP, Cancino GI, Sachewsky N, Woltjen K, Fatt MP, Morshead CM, Kaplan DR, Miller FD, Transient maternal IL-6 mediates long-lasting changes in neural stem cell pools by deregulating an endogenous self-renewal pathway. Cell Stem Cell. 2013 Nov 7;13(5):564-76 |
1 | J:206763 Gan Q, Lee A, Suzuki R, Yamagami T, Stokes A, Nguyen BC, Pleasure D, Wang J, Chen HW, Zhou CJ, Pax6 mediates ss-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells. Stem Cells. 2014 Jan;32(1):45-58 |
1 | J:176609 Goldberg LB, Aujla PK, Raetzman LT, Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis. Dev Biol. 2011 Oct 1;358(1):23-32 |
1 | J:223798 Golden EJ, Benito-Gonzalez A, Doetzlhofer A, The RNA-binding protein LIN28B regulates developmental timing in the mammalian cochlea. Proc Natl Acad Sci U S A. 2015 Jul 21;112(29):E3864-73 |
1 | J:316093 Golden EJ, Larson ED, Shechtman LA, Trahan GD, Gaillard D, Fellin TJ, Scott JK, Jones KL, Barlow LA, Onset of taste bud cell renewal starts at birth and coincides with a shift in SHH function. Elife. 2021 May 19;10:e64013 |
1 | J:235668 Goldsmith S, Lovell-Badge R, Rizzoti K, SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitary. Development. 2016 Jul 1;143(13):2376-88 |
1 | J:136180 Gontan C, de Munck A, Vermeij M, Grosveld F, Tibboel D, Rottier R, Sox2 is important for two crucial processes in lung development: branching morphogenesis and epithelial cell differentiation. Dev Biol. 2008 May 1;317(1):296-309 |
1 | J:231665 Goodliffe JW, Olmos-Serrano JL, Aziz NM, Pennings JL, Guedj F, Bianchi DW, Haydar TF, Absence of Prenatal Forebrain Defects in the Dp(16)1Yey/+ Mouse Model of Down Syndrome. J Neurosci. 2016 Mar 9;36(10):2926-44 |
1 | J:180774 Grimsley-Myers CM, Sipe CW, Wu DK, Lu X, Redundant functions of Rac GTPases in inner ear morphogenesis. Dev Biol. 2012 Feb 15;362(2):172-86 |
1 | J:196480 Grisanti L, Clavel C, Cai X, Rezza A, Tsai SY, Sennett R, Mumau M, Cai CL, Rendl M, Tbx18 targets dermal condensates for labeling, isolation, and gene ablation during embryonic hair follicle formation. J Invest Dermatol. 2013 Feb;133(2):344-53 |
1 | J:243204 Han L, Xu J, Grigg E, Slack M, Chaturvedi P, Jiang R, Zorn AM, Osr1 functions downstream of Hedgehog pathway to regulate foregut development. Dev Biol. 2017 Jul 01;427(1):72-83 |
1* | J:314664 Harada Y, Yamada M, Imayoshi I, Kageyama R, Suzuki Y, Kuniya T, Furutachi S, Kawaguchi D, Gotoh Y, Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module. Nat Commun. 2021 Nov 12;12(1):6562 |
1 | J:266597 Hartman BH, Bscke R, Ellwanger DC, Keymeulen S, Scheibinger M, Heller S, Fbxo2(VHC) mouse and embryonic stem cell reporter lines delineate in vitro-generated inner ear sensory epithelia cells and enable otic lineage selection and Cre-recombination. Dev Biol. 2018 Nov 1;443(1):64-77 |
1 | J:355958 Hartman BH, Durruthy-Durruthy R, Laske RD, Losorelli S, Heller S, Identification and characterization of mouse otic sensory lineage genes. Front Cell Neurosci. 2015;9:79 |
1 | J:241998 Haston S, Pozzi S, Carreno G, Manshaei S, Panousopoulos L, Gonzalez-Meljem JM, Apps JR, Virasami A, Thavaraj S, Gutteridge A, Forshew T, Marais R, Brandner S, Jacques TS, Andoniadou CL, Martinez-Barbera JP, MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma. Development. 2017 Jun 15;144(12):2141-2152 |
1* | J:238590 Hayashi K, Ikari T, Sugiyama G, Sugiura T, Ohyama Y, Kumamaru W, Shirasuna K, Mori Y, Involvement of the T-box transcription factor Brachyury in early-stage embryonic mouse salivary gland. Biochem Biophys Res Commun. 2016 Sep 02;477(4):814-9 |
1 | J:354192 He H, Bell SM, Davis AK, Zhao S, Sridharan A, Na CL, Guo M, Xu Y, Snowball J, Swarr DT, Zacharias WJ, Whitsett JA, PRDM3/16 regulate chromatin accessibility required for NKX2-1 mediated alveolar epithelial differentiation and function. Nat Commun. 2024 Sep 16;15(1):8112 |
1 | J:259186 Heng X, Guo Q, Leung AW, Li JY, Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6:e23253 |
1 | J:196059 Hodge RD, Garcia AJ 3rd, Elsen GE, Nelson BR, Mussar KE, Reiner SL, Ramirez JM, Hevner RF, Tbr2 expression in Cajal-Retzius cells and intermediate neuronal progenitors is required for morphogenesis of the dentate gyrus. J Neurosci. 2013 Feb 27;33(9):4165-80 |
1 | J:176483 Holmes G, Bromage TG, Basilico C, The Sox2 high mobility group transcription factor inhibits mature osteoblast function in transgenic mice. Bone. 2011 Oct;49(4):653-61 |
1 | J:218888 Hong S, Song MR, Signal transducer and activator of transcription-3 maintains the stemness of radial glia at mid-neurogenesis. J Neurosci. 2015 Jan 21;35(3):1011-23 |
1 | J:193958 Huh SH, Narhi K, Lindfors PH, Haara O, Yang L, Ornitz DM, Mikkola ML, Fgf20 governs formation of primary and secondary dermal condensations in developing hair follicles. Genes Dev. 2013 Feb 15;27(4):450-8 |
2* | J:171479 Hutton SR, Pevny LH, SOX2 expression levels distinguish between neural progenitor populations of the developing dorsal telencephalon. Dev Biol. 2011 Apr 1;352(1):40-7 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:170540 Jeong Y, Dolson DK, Waclaw RR, Matise MP, Sussel L, Campbell K, Kaestner KH, Epstein DJ, Spatial and temporal requirements for sonic hedgehog in the regulation of thalamic interneuron identity. Development. 2011 Feb;138(3):531-41 |
1 | J:334107 Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J, Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice. Hum Mol Genet. 2022 Oct 10;31(20):3504-3520 |
2* | J:194917 Juuri E, Jussila M, Seidel K, Holmes S, Wu P, Richman J, Heikinheimo K, Chuong CM, Arnold K, Hochedlinger K, Klein O, Michon F, Thesleff I, Sox2 marks epithelial competence to generate teeth in mammals and reptiles. Development. 2013 Apr;140(7):1424-32 |
2 | J:354051 Kagoshima H, Ohnishi H, Yamamoto R, Yasumoto A, Tona Y, Nakagawa T, Omori K, Yamamoto N, EBF1 Limits the Numbers of Cochlear Hair and Supporting Cells and Forms the Scala Tympani and Spiral Limbus during Inner Ear Development. J Neurosci. 2024 Feb 14;44(7) |
1 | J:235517 Kam JW, Dumontier E, Baim C, Brignall AC, Mendes da Silva D, Cowan M, Kennedy TE, Cloutier JF, RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016 May 1;143(9):1534-46 |
1 | J:240480 Kapali J, Kabat BE, Schmidt KL, Stallings CE, Tippy M, Jung DO, Edwards BS, Nantie LB, Raeztman LT, Navratil AM, Ellsworth BS, Foxo1 Is Required for Normal Somatotrope Differentiation. Endocrinology. 2016 Nov;157(11):4351-4363 |
1 | J:361142 Ke X, van Soldt B, Vlahos L, Zhou Y, Qian J, George J, Capdevila C, Glass I, Yan K, Califano A, Cardoso WV, Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate. Dev Cell. 2024 Dec 9; |
1 | J:327969 Khattar D, Fernandes S, Snowball J, Guo M, Gillen MC, Jain SS, Sinner D, Zacharias W, Swarr DT, PI3K signaling specifies proximal-distal fate by driving a developmental gene regulatory network in SOX9+ mouse lung progenitors. Elife. 2022 Aug 17;11:e67954 |
1 | J:98458 Kiernan AE, Pelling AL, Leung KK, Tang AS, Bell DM, Tease C, Lovell-Badge R, Steel KP, Cheah KS, Sox2 is required for sensory organ development in the mammalian inner ear. Nature. 2005 Apr 21;434(7036):1031-5 |
1 | J:195630 Krolewski RC, Packard A, Jang W, Wildner H, Schwob JE, Ascl1 (Mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium. PLoS One. 2012;7(12):e51737 |
1 | J:343097 Kurabayashi N, Fujii K, Otobe Y, Hiroki S, Hiratsuka M, Yoshitane H, Kazuki Y, Takao K, Neocortical neuronal production and maturation defects in the TcMAC21 mouse model of Down syndrome. iScience. 2023 Dec 15;26(12):108379 |
1* | J:215602 Lai YJ, Li MY, Yang CY, Huang KH, Tsai JC, Wang TW, TRIP6 regulates neural stem cell maintenance in the postnatal mammalian subventricular zone. Dev Dyn. 2014 Sep;243(9):1130-42 |
1 | J:254235 Lanctot AA, Guo Y, Le Y, Edens BM, Nowakowski RS, Feng Y, Loss of Brap Results in Premature G1/S Phase Transition and Impeded Neural Progenitor Differentiation. Cell Rep. 2017 Aug 1;20(5):1148-1160 |
1* | J:223203 Langer L, Sulik K, Pevny L, Cleft Palate in a Mouse Model of SOX2 Haploinsufficiency. Cleft Palate Craniofac J. 2014 Jan;51(1):110-4 |
1 | J:332513 Laporte E, De Vriendt S, Hoekx J, Vankelecom H, Interleukin-6 is dispensable in pituitary normal development and homeostasis but needed for pituitary stem cell activation following local injury. Front Endocrinol (Lausanne). 2022;13:1092063 |
2 | J:237343 Laresgoiti U, Nikolic MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL, Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016 Oct 15;143(20):3686-3699 |
1 | J:317151 Lavado A, Gangwar R, Pare J, Wan S, Fan Y, Cao X, YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development. Dev Biol. 2021 Dec;480:39-49 |
1 | J:217604 Lavado A, Ware M, Pare J, Cao X, The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Development. 2014 Nov;141(21):4182-93 |
1* | J:306217 Lee H, Ko HW, Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development. BMB Rep. 2020 Jul;53(7):367-372 |
1 | J:181920 Lee Y, Shull ER, Frappart PO, Katyal S, Enriquez-Rios V, Zhao J, Russell HR, Brown EJ, McKinnon PJ, ATR maintains select progenitors during nervous system development. EMBO J. 2012 Mar 7;31(5):1177-89 |
2* | J:202344 Lesko MH, Driskell RR, Kretzschmar K, Goldie SJ, Watt FM, Sox2 modulates the function of two distinct cell lineages in mouse skin. Dev Biol. 2013 Oct 1;382(1):15-26 |
1 | J:205567 Li K, Leung AW, Guo Q, Yang W, Li JY, Shp2-Dependent ERK Signaling Is Essential for Induction of Bergmann Glia and Foliation of the Cerebellum. J Neurosci. 2014 Jan 15;34(3):922-31 |
1 | J:306873 Li L, Jin J, Yang XJ, Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells. iScience. 2019 Oct 25;20:148-167 |
1 | J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410 |
1 | J:338836 Li Q, Jiao J, Heng Y, Lu Q, Zheng Y, Li H, Cai J, Mei M, Bao S, Prmt5 promotes ciliated cell specification of airway epithelial progenitors via transcriptional inhibition of Tp63. J Biol Chem. 2023 Jun 24;299(8):104964 |
1* | J:293091 Li Z, Li Y, Jiao J, Neural progenitor cells mediated by H2A.Z.2 regulate microglial development via Cxcl14 in the embryonic brain. Proc Natl Acad Sci U S A. 2019 Nov 26;116(48):24122-24132 |
1 | J:292113 Lin YN, Lee YS, Li SK, Tang TK, Loss of CPAP in developing mouse brain and its functional implication for human primary microcephaly. J Cell Sci. 2020 Jun 24;133(12):jcs243592 |
1 | J:146694 Lin YP, Ouchi Y, Satoh S, Watanabe S, Sox2 plays a role in the induction of amacrine and Muller glial cells in mouse retinal progenitor cells. Invest Ophthalmol Vis Sci. 2009 Jan;50(1):68-74 |
1* | J:310860 Liu S, Wang Y, Lu Y, Li W, Liu W, Ma J, Sun F, Li M, Chen ZY, Su K, Li W, The Key Transcription Factor Expression in the Developing Vestibular and Auditory Sensory Organs: A Comprehensive Comparison of Spatial and Temporal Patterns. Neural Plast. 2018;2018:7513258 |
1* | J:329558 Liu W, Chen H, Zhu X, Yu H, Expression of Calbindin-D28K in the Developing and Adult Mouse Cochlea. J Histochem Cytochem. 2022 Aug;70(8):583-596 |
1 | J:160533 Lizarraga SB, Margossian SP, Harris MH, Campagna DR, Han AP, Blevins S, Mudbhary R, Barker JE, Walsh CA, Fleming MD, Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors. Development. 2010 Jun;137(11):1907-17 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:219800 Lungova V, Verheyden JM, Herriges J, Sun X, Thibeault SL, Ontogeny of the mouse vocal fold epithelium. Dev Biol. 2015 Mar 15;399(2):263-82 |
1 | J:336095 Lupan BM, Solecki RA, Musso CM, Alsina FC, Silver DL, The exon junction complex component EIF4A3 is essential for mouse and human cortical progenitor mitosis and neurogenesis. Development. 2023 May 15;150(10) |
1 | J:362502 Lv Y, Zou W, Li L, Zhang S, Liang J, Pu J, Jiao J, IFITM2 Modulates Endocytosis Maintaining Neural Stem Cells in Developing Neocortex. Adv Sci (Weinh). 2025 Mar 7;:e2501593 |
1* | J:150757 Mak AC, Szeto IY, Fritzsch B, Cheah KS, Differential and overlapping expression pattern of SOX2 and SOX9 in inner ear development. Gene Expr Patterns. 2009 Sep;9(6):444-53 |
1 | J:286398 Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, Furuse T, Shibuya H, Yasuda Y, Yamamori H, Fujimoto M, Nagayasu K, Yamamoto K, Kitagawa K, Miura H, Gotoda-Nishimura N, Igarashi H, Hayashida M, Baba M, Kondo M, Hasebe S, Ueshima K, Kasai A, Ago Y, Hayata-Takano A, Shintani N, Iguchi T, Sato M, Yamaguchi S, Tamura M, Wakana S, Yoshiki A, Watabe AM, Okano H, Takuma K, Hashimoto R, Hashimoto H, Nakazawa T, Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes. Nat Commun. 2020 Feb 26;11(1):859 |
1 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
1 | J:252094 Matuzelski E, Bunt J, Harkins D, Lim JWC, Gronostajski RM, Richards LJ, Harris L, Piper M, Transcriptional regulation of Nfix by NFIB drives astrocytic maturation within the developing spinal cord. Dev Biol. 2017 Dec 15;432(2):286-297 |
1 | J:218941 Meier F, Giesert F, Delic S, Faus-Kessler T, Matheus F, Simeone A, Holter SM, Kuhn R, Weisenhorn DM, Wurst W, Prakash N, FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS One. 2014;9(7):e101124 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:332403 Miller SR, Perera SN, Benito C, Stott SR, Baker CV, Evidence for a Notch1-mediated transition during olfactory ensheathing cell development. J Anat. 2016 Sep;229(3):369-83 |
1 | J:138323 Miyagi S, Masui S, Niwa H, Saito T, Shimazaki T, Okano H, Nishimoto M, Muramatsu M, Iwama A, Okuda A, Consequence of the loss of Sox2 in the developing brain of the mouse. FEBS Lett. 2008 Aug 6;582(18):2811-5 |
1 | J:113118 Miyagi S, Nishimoto M, Saito T, Ninomiya M, Sawamoto K, Okano H, Muramatsu M, Oguro H, Iwama A, Okuda A, The Sox2 regulatory region 2 functions as a neural stem cell-specific enhancer in the telencephalon. J Biol Chem. 2006 May 12;281(19):13374-81 |
1 | J:306063 Morandell J, Schwarz LA, Basilico B, Tasciyan S, Dimchev G, Nicolas A, Sommer C, Kreuzinger C, Dotter CP, Knaus LS, Dobler Z, Cacci E, Schur FKM, Danzl JG, Novarino G, Cul3 regulates cytoskeleton protein homeostasis and cell migration during a critical window of brain development. Nat Commun. 2021 May 24;12(1):3058 |
1* | J:324129 Moreci RS, Lechler T, KIF18B is a cell type-specific regulator of spindle orientation in the epidermis. Mol Biol Cell. 2021 Nov 1;32(21):ar29 |
1 | J:186443 Muller Smith K, Williamson TL, Schwartz ML, Vaccarino FM, Impaired motor coordination and disrupted cerebellar architecture in Fgfr1 and Fgfr2 double knockout mice. Brain Res. 2012 Jun 15;1460:12-24 |
1 | J:188114 Munnamalai V, Hayashi T, Bermingham-McDonogh O, Notch prosensory effects in the Mammalian cochlea are partially mediated by fgf20. J Neurosci. 2012 Sep 12;32(37):12876-84 |
1 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
1 | J:353047 Nevorankova P, Sulcova M, Kavkova M, Zimcik D, Balkova SM, Peleskova K, Kristekova D, Jakesova V, Zikmund T, Kaiser J, Hola LI, Kolar M, Buchtova M, Region-specific gene expression profiling of early mouse mandible uncovered SATB2 as a key molecule for teeth patterning. Sci Rep. 2024 Aug 6;14(1):18212 |
1 | J:326948 Ng KJ, Lim J, Tan YN, Quek D, Lim Z, Pantelireis N, Clavel C, Sox2 in the dermal papilla regulates hair follicle pigmentation. Cell Rep. 2022 Jul 19;40(3):111100 |
1 | J:267954 Nguyen MB, Cohen I, Kumar V, Xu Z, Bar C, Dauber-Decker KL, Tsai PC, Marangoni P, Klein OD, Hsu YC, Chen T, Mikkola ML, Ezhkova E, FGF signalling controls the specification of hair placode-derived SOX9 positive progenitors to Merkel cells. Nat Commun. 2018 Jun 13;9(1):2333 |
2* | J:313342 Nichols DH, Bouma JE, Kopecky BJ, Jahan I, Beisel KW, He DZZ, Liu H, Fritzsch B, Interaction with ectopic cochlear crista sensory epithelium disrupts basal cochlear sensory epithelium development in Lmx1a mutant mice. Cell Tissue Res. 2020 Jun;380(3):435-448 |
1 | J:272073 Nicola Z, Fabel K, Kempermann G, Development of the adult neurogenic niche in the hippocampus of mice. Front Neuroanat. 2015;9:53 |
1* | J:297164 Nie X, Zheng J, Cruciger M, Yang P, Mao JJ, mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev Biol. 2020 Nov 1;467(1-2):77-87 |
1 | J:240892 Nitarska J, Smith JG, Sherlock WT, Hillege MM, Nott A, Barshop WD, Vashisht AA, Wohlschlegel JA, Mitter R, Riccio A, A Functional Switch of NuRD Chromatin Remodeling Complex Subunits Regulates Mouse Cortical Development. Cell Rep. 2016 Nov 01;17(6):1683-1698 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
2 | J:282790 Ogawa Y, Sasanuma Y, Shitara S, Koshizuka A, Okada R, Sakuraba H, Oishi K, Abnormal organization during neurodevelopment in a mouse model of Sandhoff disease. Neurosci Res. 2019 Jul 21; |
1 | J:242339 Ohayon D, Garces A, Joly W, Soukkarieh C, Takagi T, Sabourin JC, Agius E, Darling DS, De Santa Barbara P, Higashi Y, Stolt CC, Hugnot JP, Richardson WD, Carroll P, Pattyn A, Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Cell Rep. 2016 Nov 01;17(6):1473-1481 |
1 | J:354217 Ohyama K, Shinohara HM, Takayama N, Ogawa R, Omura S, Hayashida M, Takahashi T, Differentiation stage-specific expression of transcriptional regulators for epithelial mesenchymal transition in dentate granule progenitors. Front Neurosci. 2024;18:1425849 |
2* | J:112945 Okubo T, Pevny LH, Hogan BL, Sox2 is required for development of taste bud sensory cells. Genes Dev. 2006 Oct 1;20(19):2654-9 |
1* | J:311540 Oliver BL, Young CA, Munnamalai V, Spatial and temporal expression of PORCN is highly dynamic in the developing mouse cochlea. Gene Expr Patterns. 2021 Sep 20;42:119214 |
1 | J:173538 Packard A, Schnittke N, Romano RA, Sinha S, Schwob JE, {Delta}Np63 regulates stem cell dynamics in the Mammalian olfactory epithelium. J Neurosci. 2011 Jun 15;31(24):8748-59 |
1 | J:246653 Park JC, Jeong WJ, Kim MY, Min D, Choi KY, Retinoic-acid-mediated HRas stabilization induces neuronal differentiation of neural stem cells during brain development. J Cell Sci. 2016 Aug 01;129(15):2997-3007 |
1 | J:287008 Pearson CA, Moore DM, Tucker HO, Dekker JD, Hu H, Miquelajauregui A, Novitch BG, Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates. Cell Rep. 2020 Feb 11;30(6):1964-1981.e3 |
1* | J:360369 Pelenyi A, Atterton C, Jones J, Currey L, Al-Khalily M, Wright L, Kurniawan ND, Thor S, Piper M, Expression of the Hippo pathway effector, TEAD1, within the developing murine forebrain. Gene Expr Patterns. 2024 Dec;54:119384 |
1 | J:290493 Peng YR, James RE, Yan W, Kay JN, Kolodkin AL, Sanes JR, Binary Fate Choice between Closely Related Interneuronal Types Is Determined by a Fezf1-Dependent Postmitotic Transcriptional Switch. Neuron. 2020 Feb 5;105(3):464-474.e6 |
1 | J:187354 Poche RA, Furuta Y, Chaboissier MC, Schedl A, Behringer RR, Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Muller glial cell development. J Comp Neurol. 2008 Sep 20;510(3):237-50 |
2 | J:324528 Qu R, Gupta K, Dong D, Jiang Y, Landa B, Saez C, Strickland G, Levinsohn J, Weng PL, Taketo MM, Kluger Y, Myung P, Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients. Dev Cell. 2022 Apr 25;57(8):1053-1067.e5 |
1* | J:332883 Rastegar-Pouyani S, Kennedy TE, Kania A, Somatotopy of Mouse Spinothalamic Innervation and the Localization of a Noxious Stimulus Requires Deleted in Colorectal Carcinoma Expression by Phox2a Neurons. J Neurosci. 2022 Oct 19;42(42):7885-7899 |
1 | J:217395 Ritchie K, Watson LA, Davidson B, Jiang Y, Berube NG, ATRX is required for maintenance of the neuroprogenitor cell pool in the embryonic mouse brain. Biol Open. 2014;3(12):1158-63 |
1 | J:202984 Rockich BE, Hrycaj SM, Shih HP, Nagy MS, Ferguson MA, Kopp JL, Sander M, Wellik DM, Spence JR, Sox9 plays multiple roles in the lung epithelium during branching morphogenesis. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4456-64 |
1 | J:220958 Rosenthal EH, Tonchev AB, Stoykova A, Chowdhury K, Regulation of archicortical arealization by the transcription factor Zbtb20. Hippocampus. 2012 Nov;22(11):2144-56 |
1* | J:268084 Saha A, Tiwari S, Dharmarajan S, Otteson DC, Belecky-Adams TL, Class I histone deacetylases in retinal progenitors and differentiating ganglion cells. Gene Expr Patterns. 2018 Dec;30:37-48 |
1 | J:286655 Sakamoto S, Tateya T, Omori K, Kageyama R, Id genes are required for morphogenesis and cellular patterning in the developing mammalian cochlea. Dev Biol. 2020 Apr 15;460(2):164-175 |
1 | J:248731 Salehi P, Ge MX, Gundimeda U, Michelle Baum L, Lael Cantu H, Lavinsky J, Tao L, Myint A, Cruz C, Wang J, Nikolakopoulou AM, Abdala C, Kelley MW, Ohyama T, Coate TM, Friedman RA, Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea. PLoS Genet. 2017 Oct;13(10):e1007048 |
1 | J:301269 Sankoda N, Tanabe W, Tanaka A, Shibata H, Woltjen K, Chiba T, Haga H, Sakai Y, Mandai M, Yamamoto T, Yamada Y, Uemoto S, Kawaguchi Y, Epithelial expression of Gata4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice. Nat Commun. 2021 Jan 25;12(1):560 |
1 | J:327338 Sartoretti MM, Campetella CA, Lanuza GM, Dbx1 controls the development of astrocytes of the intermediate spinal cord by modulating Notch signaling. Development. 2022 Aug 1;149(15):dev200750 |
1 | J:345231 Satta JP, Lan Q, Taketo MM, Mikkola ML, Stabilization of Epithelial beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis. J Invest Dermatol. 2023 Dec 28; |
1 | J:191793 Schnatwinkel C, Niswander L, Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice. PLoS One. 2012;7(9):e44871 |
1 | J:316218 Schoof M, Hellwig M, Harrison L, Holdhof D, Lauffer MC, Niesen J, Virdi S, Indenbirken D, Schuller U, The basic helix-loop-helix transcription factor TCF4 impacts brain architecture as well as neuronal morphology and differentiation. Eur J Neurosci. 2020 Jun;51(11):2219-2235 |
1 | J:296487 Schoof M, Launspach M, Holdhof D, Nguyen L, Engel V, Filser S, Peters F, Immenschuh J, Hellwig M, Niesen J, Mall V, Ertl-Wagner B, Hagel C, Spohn M, Lutz B, Sedlacik J, Indenbirken D, Merk DJ, Schuller U, The transcriptional coactivator and histone acetyltransferase CBP regulates neural precursor cell development and migration. Acta Neuropathol Commun. 2019 Dec 5;7(1):199 |
2 | J:305768 Selvadurai HJ, Luis E, Desai K, Lan X, Vladoiu MC, Whitley O, Galvin C, Vanner RJ, Lee L, Whetstone H, Kushida M, Nowakowski T, Diamandis P, Hawkins C, Bader G, Kriegstein A, Taylor MD, Dirks PB, Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2(+) Granule Neuron Precursor. Cell Rep. 2020 Apr 14;31(2):107511 |
1* | J:311166 Semenza ER, Harraz MM, Abramson E, Malla AP, Vasavda C, Gadalla MM, Kornberg MD, Snyder SH, Roychaudhuri R, D-cysteine is an endogenous regulator of neural progenitor cell dynamics in the mammalian brain. Proc Natl Acad Sci U S A. 2021 Sep 28;118(39):e2110610118 |
1 | J:215784 Sennett R, Rezza A, Dauber KL, Clavel C, Rendl M, Cxcr4 is transiently expressed in both epithelial and mesenchymal compartments of nascent hair follicles but is not required for follicle formation. Exp Dermatol. 2014 Oct;23(10):748-50 |
1 | J:327067 Shang L, Mao D, Li Z, Gao X, Deng J, Neuroglobin Is Involved in the Hypoxic Stress Response in the Brain. Biomed Res Int. 2022;2022:8263373 |
1 | J:328873 Shang Z, Yang L, Wang Z, Tian Y, Gao Y, Su Z, Guo R, Li W, Liu G, Li X, Yang Z, Li Z, Zhang Z, The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity. Front Cell Dev Biol. 2022;10:948331 |
1 | J:278483 Shi L, Qalieh A, Lam MM, Keil JM, Kwan KY, Robust elimination of genome-damaged cells safeguards against brain somatic aneuploidy following Knl1 deletion. Nat Commun. 2019 Jun 13;10(1):2588 |
1 | J:217677 Snitow ME, Li S, Morley MP, Rathi K, Lu MM, Kadzik RS, Stewart KM, Morrisey EE, Ezh2 represses the basal cell lineage during lung endoderm development. Development. 2015 Jan 1;142(1):108-17 |
1 | J:218837 Song H, Lee B, Pyun D, Guimera J, Son Y, Yoon J, Baek K, Wurst W, Jeong Y, Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation. Dev Biol. 2015 Feb 15;398(2):280-91 |
1* | J:324710 Stanton-Turcotte D, Hsu K, Moore SA, Yamada M, Fawcett JP, Iulianella A, Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development. J Neurosci. 2022 May 11;42(19):3931-3948 |
3 | J:137641 Stringer EJ, Pritchard CA, Beck F, Cdx2 initiates histodifferentiation of the midgut endoderm. FEBS Lett. 2008 Jul 23;582(17):2555-60 |
1* | J:316648 Suflita MT, Pfaltzgraff ER, Mundell NA, Pevny LH, Labosky PA, Ground-state transcriptional requirements for skin-derived precursors. Stem Cells Dev. 2013 Jun 15;22(12):1779-88 |
1* | J:203065 Sugiyama T, Osumi N, Katsuyama Y, The germinal matrices in the developing dentate gyrus are composed of neuronal progenitors at distinct differentiation stages. Dev Dyn. 2013 Dec;242(12):1442-53 |
1 | J:216104 Sugiyama T, Osumi N, Katsuyama Y, A novel cell migratory zone in the developing hippocampal formation. J Comp Neurol. 2014 Oct 15;522(15):3520-38 |
1 | J:237541 Sun Z, Yu W, Sanz Navarro M, Sweat M, Eliason S, Sharp T, Liu H, Seidel K, Zhang L, Moreno M, Lynch T, Holton NE, Rogers L, Neff T, Goodheart MJ, Michon F, Klein OD, Chai Y, Dupuy A, Engelhardt JF, Chen Z, Amendt BA, Sox2 and Lef-1 interact with Pitx2 to regulate incisor development and stem cell renewal. Development. 2016 Nov 15;143(22):4115-4126 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
1 | J:278287 Tang T, Zhang Y, Wang Y, Cai Z, Lu Z, Li L, Huang R, Hagelkruys A, Matthias P, Zhang H, Seiser C, Xie Y, HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development. Neuron. 2019 Mar 20;101(6):1117-1133.e5 |
1* | J:264553 Tarchini B, Longo-Guess C, Tian C, Tadenev ALD, Devanney N, Johnson KR, A spontaneous mouse deletion in Mctp1 uncovers a long-range cis-regulatory region crucial for NR2F1 function during inner ear development. Dev Biol. 2018 Nov 15;443(2):153-164 |
1 | J:171513 Tian Y, Zhang Y, Hurd L, Hannenhalli S, Liu F, Lu MM, Morrisey EE, Regulation of lung endoderm progenitor cell behavior by miR302/367. Development. 2011 Apr;138(7):1235-45 |
1 | J:343099 Tonosaki M, Fujimori A, Yaoi T, Itoh K, Loss of Aspm causes increased apoptosis of developing neural cells during mouse cerebral corticogenesis. PLoS One. 2023;18(11):e0294893 |
1 | J:363296 Tsampoula M, Tarampoulous I, Manolakou T, Ninou E, Politis PK, The Neurodevelopmental Disorders Associated Gene Rnf113a Regulates Survival and Differentiation Properties of Neural Stem Cells. Stem Cells. 2022 Jul 27;40(7):678-690 |
1 | J:163859 Tucker ES, Lehtinen MK, Maynard T, Zirlinger M, Dulac C, Rawson N, Pevny L, Lamantia AS, Proliferative and transcriptional identity of distinct classes of neural precursors in the mammalian olfactory epithelium. Development. 2010 Aug 1;137(15):2471-81 |
1 | J:266598 Ustiyan V, Bolte C, Zhang Y, Han L, Xu Y, Yutzey KE, Zorn AM, Kalin TV, Shannon JM, Kalinichenko VV, FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme. Dev Biol. 2018 Nov 1;443(1):50-63 |
1 | J:293532 Vaid S, Camp JG, Hersemann L, Eugster Oegema C, Heninger AK, Winkler S, Brandl H, Sarov M, Treutlein B, Huttner WB, Namba T, A novel population of Hopx-dependent basal radial glial cells in the developing mouse neocortex. Development. 2018 Oct 18;145(20):dev169276 |
1 | J:340444 Veithen M, Huyghe A, Van Den Ackerveken P, Fukada SI, Kokubo H, Breuskin I, Nguyen L, Delacroix L, Malgrange B, Sox9 Inhibits Cochlear Hair Cell Fate by Upregulating Hey1 and HeyL Antagonists of Atoh1. Cells. 2023 Aug 25;12(17) |
1 | J:241851 Villani R, Hodgson S, Legrand J, Greaney J, Wong HY, Pichol-Thievend C, Adolphe C, Wainwight B, Francois M, Khosrotehrani K, Dominant-negative Sox18 function inhibits dermal papilla maturation and differentiation in all murine hair types. Development. 2017 May 15;144(10):1887-1895 |
1 | J:233479 Vong KI, Leung CK, Behringer RR, Kwan KM, Sox9 is critical for suppression of neurogenesis but not initiation of gliogenesis in the cerebellum. Mol Brain. 2015;8:25 |
1 | J:132518 Vue TY, Aaker J, Taniguchi A, Kazemzadeh C, Skidmore JM, Martin DM, Martin JF, Treier M, Nakagawa Y, Characterization of progenitor domains in the developing mouse thalamus. J Comp Neurol. 2007 Nov 1;505(1):73-91 |
1 | J:147427 Vue TY, Bluske K, Alishahi A, Yang LL, Koyano-Nakagawa N, Novitch B, Nakagawa Y, Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice. J Neurosci. 2009 Apr 8;29(14):4484-97 |
1* | J:316179 Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y, An epigenetic circuit controls neurogenic programs during neocortex development. Development. 2021;148:dev199772 |
1 | J:265679 Wang B, Joo JH, Mount R, Teubner BJW, Krenzer A, Ward AL, Ichhaporia VP, Adams EJ, Khoriaty R, Peters ST, Pruett-Miller SM, Zakharenko SS, Ginsburg D, Kundu M, The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018 Aug 1;128(8):3319-3332 |
1 | J:238248 Wang L, Hou S, Han YG, Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex. Nat Neurosci. 2016 Jul;19(7):888-96 |
1 | J:302429 Wang Z, Jung JS, Inbar TC, Rangoussis KM, Faaborg-Andersen C, Coate TM, The Purinergic Receptor P2rx3 is Required for Spiral Ganglion Neuron Branch Refinement during Development. eNeuro. 2020 Jul/Aug;7(4):ENEURO.0179-20.2020 |
1 | J:206929 Watson LA, Wang X, Elbert A, Kernohan KD, Galjart N, Berube NG, Dual Effect of CTCF Loss on Neuroprogenitor Differentiation and Survival. J Neurosci. 2014 Feb 19;34(8):2860-70 |
1 | J:329947 Wei W, Tang X, Jiang N, Ni C, He H, Sun S, Yu M, Yu C, Qiu M, Yan D, Zhou Z, Song Y, Liu H, Zhao B, Lin X, Chromatin remodeler Znhit1 controls bone morphogenetic protein signaling in embryonic lung tissue branching. J Biol Chem. 2022 Sep 14;298(10):102490 |
1 | J:344966 Wei Y, Wang X, Ma Z, Xiang P, Liu G, Yin B, Hou L, Shu P, Liu W, Peng X, Sirt6 regulates the proliferation of neural precursor cells and cortical neurogenesis in mice. iScience. 2024 Feb 16;27(2):108706 |
2 | J:278634 Wilkerson BA, Chitsazan AD, VandenBosch LS, Wilken MS, Reh TA, Bermingham-McDonogh O, Open chromatin dynamics in prosensory cells of the embryonic mouse cochlea. Sci Rep. 2019 Jun 21;9(1):9060 |
2* | J:104307 Wilson ME, Yang KY, Kalousova A, Lau J, Kosaka Y, Lynn FC, Wang J, Mrejen C, Episkopou V, Clevers HC, German MS, The HMG Box Transcription Factor Sox4 Contributes to the Development of the Endocrine Pancreas. Diabetes. 2005 Dec;54(12):3402-9 |
1 | J:306208 Wu J, Tian Y, Han L, Liu C, Sun T, Li L, Yu Y, Lamichhane B, D'Souza RN, Millar SE, Krumlauf R, Ornitz DM, Feng JQ, Klein O, Zhao H, Zhang F, Linhardt RJ, Wang X, FAM20B-catalyzed glycosaminoglycans control murine tooth number by restricting FGFR2b signaling. BMC Biol. 2020 Jul 14;18(1):87 |
1 | J:361525 Wu M, Jia G, Liu Y, Lou Y, Li Y, Xia M, Li H, Li W, PKM2 controls cochlear development through lactate-dependent transcriptional regulation. Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2410829122 |
1 | J:354849 Wutikeli H, Yu Y, Zhang T, Cao J, Nawy S, Shen Y, Role of Elavl-like RNA-binding protein in retinal development and signal transduction. Biochim Biophys Acta Mol Basis Dis. 2024 Sep 20;1871(1):167518 |
1 | J:234179 Xiao Y, Thoresen DT, Miao L, Williams JS, Wang C, Atit RP, Wong SY, Brownell I, A Cascade of Wnt, Eda, and Shh Signaling Is Essential for Touch Dome Merkel Cell Development. PLoS Genet. 2016 Jul;12(7):e1006150 |
1 | J:317033 Xie C, Abrams SR, Herranz-Perez V, Garcia-Verdugo JM, Reiter JF, Endoderm development requires centrioles to restrain p53-mediated apoptosis in the absence of ERK activity. Dev Cell. 2021 Dec 20;56(24):3334-3348.e6 |
1 | J:273281 Xu D, Yao M, Wang Y, Yuan L, Hoeck JD, Yu J, Liu L, Yeap YYC, Zhang W, Zhang F, Feng Y, Ma T, Wang Y, Ng DCH, Niu X, Su B, Behrens A, Xu Z, MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis. PLoS Biol. 2018 Dec;16(12):e2006613 |
1* | J:214315 Yamada M, Clark J, Iulianella A, MLLT11/AF1q is differentially expressed in maturing neurons during development. Gene Expr Patterns. 2014 Jul;15(2):80-7 |
1 | J:209314 Yamamoto H, Maruo T, Majima T, Ishizaki H, Tanaka-Okamoto M, Miyoshi J, Mandai K, Takai Y, Genetic deletion of afadin causes hydrocephalus by destruction of adherens junctions in radial glial and ependymal cells in the midbrain. PLoS One. 2013;8(11):e80356 |
2 | J:345074 Yamanaka T, Kurosawa M, Yoshida A, Shimogori T, Hiyama A, Maity SN, Hattori N, Matsui H, Nukina N, The transcription factor NF-YA is crucial for neural progenitor maintenance during brain development. J Biol Chem. 2024 Jan 8;300(2):105629 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
1 | J:264522 Youngblood JL, Coleman TF, Davis SW, Regulation of Pituitary Progenitor Differentiation by beta-Catenin. Endocrinology. 2018 Sep 1;159(9):3287-3305 |
1 | J:363160 Yuizumi N, Harada Y, Kuniya T, Sunabori T, Koike M, Wakabayashi M, Ishihama Y, Suzuki Y, Kawaguchi D, Gotoh Y, Maintenance of neural stem-progenitor cells by the lysosomal biosynthesis regulators TFEB and TFE3 in the embryonic mouse telencephalon. Stem Cells. 2021 Jul;39(7):929-944 |
1 | J:332095 Zhang K, Yao E, Chuang E, Chen B, Chuang EY, Chuang PT, mTORC1 signaling facilitates differential stem cell differentiation to shape the developing murine lung and is associated with mitochondrial capacity. Nat Commun. 2022 Nov 25;13(1):7252 |
1 | J:299730 Zhang L, Jing H, Li H, Chen W, Luo B, Zhang H, Dong Z, Li L, Su H, Xiong WC, Mei L, Neddylation is critical to cortical development by regulating Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26448-26459 |
1 | J:362758 Zhang L, Li Y, Hu Y, Chen M, Cen C, Chen M, Lin L, Zhou J, Wang M, Cui X, Tang F, Gao F, Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression. FASEB J. 2022 Feb;36(2):e22131 |
3* | J:187393 Zhang L, Yuan G, Liu H, Lin H, Wan C, Chen Z, Expression pattern of Sox2 during mouse tooth development. Gene Expr Patterns. 2012 Aug;12(7-8):273-81 |
1 | J:287752 Zhang W, Ma L, Yang M, Shao Q, Xu J, Lu Z, Zhao Z, Chen R, Chai Y, Chen JF, Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes. Genes Dev. 2020 Apr 1;34(7-8):580-597 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
1 | J:324298 Zhou J, Liu G, Zhang X, Wu C, Ma M, Wu J, Hou L, Yin B, Qiang B, Shu P, Peng X, Comparison of the Spatiotemporal Expression Patterns of Three Cre Lines, Emx1IRES-Cre, D6-Cre and hGFAP-Cre, Commonly Used in Neocortical Development Research. Cereb Cortex. 2022 Apr 5;32(8):1668-1681 |
1 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
Sox3 SRY (sex determining region Y)-box 3 (Synonyms: Sox-3) | |
Results | Reference |
1 | J:204443 Egan CM, Nyman U, Skotte J, Streubel G, Turner S, O'Connell DJ, Rraklli V, Dolan MJ, Chadderton N, Hansen K, Farrar GJ, Helin K, Holmberg J, Bracken AP, CHD5 is required for neurogenesis and has a dual role in facilitating gene expression and polycomb gene repression. Dev Cell. 2013 Aug 12;26(3):223-36 |
1 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:175105 Shen JH, Ingraham HA, Regulation of the orphan nuclear receptor steroidogenic factor 1 by Sox proteins. Mol Endocrinol. 2002 Mar;16(3):529-40 |
1 | J:116148 Stolt CC, Schlierf A, Lommes P, Hillgartner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M, SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell. 2006 Nov;11(5):697-709 |
Sox4 SRY (sex determining region Y)-box 4 (Synonyms: Sox-4) | |
Results | Reference |
1 | J:225805 Chen C, Lee GA, Pourmorady A, Sock E, Donoghue MJ, Orchestration of Neuronal Differentiation and Progenitor Pool Expansion in the Developing Cortex by SoxC Genes. J Neurosci. 2015 Jul 22;35(29):10629-42 |
1* | J:63842 Cheung M, Abu-Elmagd M, Clevers H, Scotting PJ, Roles of Sox4 in central nervous system development. Brain Res Mol Brain Res. 2000 Jun 23;79(1-2):180-91 |
1 | J:306221 Chiang SY, Wu HC, Lin SY, Chen HY, Wang CF, Yeh NH, Shih JH, Huang YS, Kuo HC, Chou SJ, Chen RH, Usp11 controls cortical neurogenesis and neuronal migration through Sox11 stabilization. Sci Adv. 2021 Feb;7(7) |
1* | J:173070 Dy P, Penzo-Mendez A, Wang H, Pedraza CE, Macklin WB, Lefebvre V, The three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular properties. Nucleic Acids Res. 2008 May;36(9):3101-17 |
1 | J:269420 Franz H, Villarreal A, Heidrich S, Videm P, Kilpert F, Mestres I, Calegari F, Backofen R, Manke T, Vogel T, DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex. Nucleic Acids Res. 2019 Jan 10;47(1):168-183 |
1* | J:86790 Gitler AD, Lu MM, Jiang YQ, Epstein JA, Gruber PJ, Molecular markers of cardiac endocardial cushion development. Dev Dyn. 2003 Dec;228(4):643-50 |
1 | J:332402 Hockman D, Adameyko I, Kaucka M, Barraud P, Otani T, Hunt A, Hartwig AC, Sock E, Waithe D, Franck MCM, Ernfors P, Ehinger S, Howard MJ, Brown N, Reese J, Baker CVH, Striking parallels between carotid body glomus cell and adrenal chromaffin cell development. Dev Biol. 2018 Dec 1;444 Suppl 1(Suppl 1):S308-S324 |
1 | J:137911 Hoser M, Potzner MR, Koch JM, Bosl MR, Wegner M, Sock E, Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors. Mol Cell Biol. 2008 Aug;28(15):4675-87 |
1* | J:198192 Huang J, Arsenault M, Kann M, Lopez-Mendez C, Saleh M, Wadowska D, Taglienti M, Ho J, Miao Y, Sims D, Spears J, Lopez A, Wright G, Hartwig S, The transcription factor Sry-related HMG box-4 (SOX4) is required for normal renal development in vivo. Dev Dyn. 2013 Jun;242(6):790-9 |
1 | J:199663 Jiang Y, Ding Q, Xie X, Libby RT, Lefebvre V, Gan L, Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells. J Biol Chem. 2013 Jun 21;288(25):18429-38 |
2 | J:325428 Liu J, Yang M, Su M, Liu B, Zhou K, Sun C, Ba R, Yu B, Zhang B, Zhang Z, Fan W, Wang K, Zhong M, Han J, Zhao C, FOXG1 sequentially orchestrates subtype specification of postmitotic cortical projection neurons. Sci Adv. 2022 May 27;8(21):eabh3568 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:279389 Miao Q, Hill MC, Chen F, Mo Q, Ku AT, Ramos C, Sock E, Lefebvre V, Nguyen H, SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair. Nat Commun. 2019 Sep 6;10(1):4042 |
1 | J:165741 Rojas A, Schachterle W, Xu SM, Martin F, Black BL, Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer. Dev Biol. 2010 Oct 15;346(2):346-55 |
1 | J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1* | J:104307 Wilson ME, Yang KY, Kalousova A, Lau J, Kosaka Y, Lynn FC, Wang J, Mrejen C, Episkopou V, Clevers HC, German MS, The HMG Box Transcription Factor Sox4 Contributes to the Development of the Endocrine Pancreas. Diabetes. 2005 Dec;54(12):3402-9 |
1 | J:220744 Xu EE, Krentz NA, Tan S, Chow SZ, Tang M, Nian C, Lynn FC, SOX4 cooperates with neurogenin 3 to regulate endocrine pancreas formation in mouse models. Diabetologia. 2015 May;58(5):1013-23 |
Sox5 SRY (sex determining region Y)-box 5 (Synonyms: A730017D01Rik) | |
Results | Reference |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1* | J:139199 Dumitriu B, Patrick MR, Petschek JP, Cherukuri S, Klingmuller U, Fox PL, Lefebvre V, Sox6 cell-autonomously stimulates erythroid cell survival, proliferation, and terminal maturation and is thereby an important enhancer of definitive erythropoiesis during mouse development. Blood. 2006 Aug 15;108(4):1198-207 |
1 | J:160493 Dy P, Smits P, Silvester A, Penzo-Mendez A, Dumitriu B, Han Y, de la Motte CA, Kingsley DM, Lefebvre V, Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. Dev Biol. 2010 May 15;341(2):346-59 |
1 | J:269420 Franz H, Villarreal A, Heidrich S, Videm P, Kilpert F, Mestres I, Calegari F, Backofen R, Manke T, Vogel T, DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex. Nucleic Acids Res. 2019 Jan 10;47(1):168-183 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:159978 Gao Z, Kim GH, Mackinnon AC, Flagg AE, Bassett B, Earley JU, Svensson EC, Ets1 is required for proper migration and differentiation of the cardiac neural crest. Development. 2010 May;137(9):1543-51 |
1 | J:315293 Kumamoto T, Toma K, Gunadi, McKenna WL, Kasukawa T, Katzman S, Chen B, Hanashima C, Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013 Mar 28;3(3):931-45 |
2 | J:325428 Liu J, Yang M, Su M, Liu B, Zhou K, Sun C, Ba R, Yu B, Zhang B, Zhang Z, Fan W, Wang K, Zhong M, Han J, Zhao C, FOXG1 sequentially orchestrates subtype specification of postmitotic cortical projection neurons. Sci Adv. 2022 May 27;8(21):eabh3568 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1* | J:74344 Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B, The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 2002 Jan 11;108(1):17-29 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1 | J:173055 Stolt CC, Lommes P, Hillgartner S, Wegner M, The transcription factor Sox5 modulates Sox10 function during melanocyte development. Nucleic Acids Res. 2008 Oct;36(17):5427-40 |
1 | J:116148 Stolt CC, Schlierf A, Lommes P, Hillgartner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M, SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell. 2006 Nov;11(5):697-709 |
1 | J:159315 Xie Z, Ma X, Ji W, Zhou G, Lu Y, Xiang Z, Wang YX, Zhang L, Hu Y, Ding YQ, Zhang WJ, Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6510-5 |
1* | J:317374 Zhang M, Lu Q, Miller AH, Barnthouse NC, Wang J, Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage. Int J Biochem Cell Biol. 2016 Mar;72:125-134 |
Sox6 SRY (sex determining region Y)-box 6 | |
Results | Reference |
1 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:154935 Batista-Brito R, Rossignol E, Hjerling-Leffler J, Denaxa M, Wegner M, Lefebvre V, Pachnis V, Fishell G, The cell-intrinsic requirement of Sox6 for cortical interneuron development. Neuron. 2009 Aug 27;63(4):466-81 |
1* | J:139199 Dumitriu B, Patrick MR, Petschek JP, Cherukuri S, Klingmuller U, Fox PL, Lefebvre V, Sox6 cell-autonomously stimulates erythroid cell survival, proliferation, and terminal maturation and is thereby an important enhancer of definitive erythropoiesis during mouse development. Blood. 2006 Aug 15;108(4):1198-207 |
1 | J:160493 Dy P, Smits P, Silvester A, Penzo-Mendez A, Dumitriu B, Han Y, de la Motte CA, Kingsley DM, Lefebvre V, Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. Dev Biol. 2010 May 15;341(2):346-59 |
1 | J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132 |
1 | J:336092 Knowles SJ, Stafford AM, Zaman T, Angara K, Williams MR, Newbern JM, Vogt D, Distinct hyperactive RAS/MAPK alleles converge on common GABAergic interneuron core programs. Development. 2023 May 15;150(10):dev201371 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1 | J:214153 Rudrabhatla P, Utreras E, Jaffe H, Kulkarni AB, Regulation of sox6 by cyclin dependent kinase 5 in brain. PLoS One. 2014;9(3):e89310 |
1* | J:358134 Soma S, Murakami K, Fukuchi Y, Kunimoto H, Nakajima H, O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. Stem Cells. 2024 Jan 13;42(1):55-63 |
1 | J:116148 Stolt CC, Schlierf A, Lommes P, Hillgartner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M, SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell. 2006 Nov;11(5):697-709 |
1 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
1 | J:241609 Taglietti V, Maroli G, Cermenati S, Monteverde S, Ferrante A, Rossi G, Cossu G, Beltrame M, Messina G, Nfix Induces a Switch in Sox6 Transcriptional Activity to Regulate MyHC-I Expression in Fetal Muscle. Cell Rep. 2016 Nov 22;17(9):2354-2366 |
1* | J:337458 Waldhauser V, Baroti T, Frob F, Wegner M, PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12) |
1 | J:282590 Wei S, Du H, Li Z, Tao G, Xu Z, Song X, Shang Z, Su Z, Chen H, Wen Y, Liu G, You Y, Zhang Z, Yang Z, Transcription factors Sp8 and Sp9 regulate the development of caudal ganglionic eminence-derived cortical interneurons. J Comp Neurol. 2019 Dec 1;527(17):2860-2874 |
1* | J:115753 Yi Z, Cohen-Barak O, Hagiwara N, Kingsley PD, Fuchs DA, Erickson DT, Epner EM, Palis J, Brilliant MH, Sox6 directly silences epsilon globin expression in definitive erythropoiesis. PLoS Genet. 2006 Feb;2(2):e14 |
1* | J:317374 Zhang M, Lu Q, Miller AH, Barnthouse NC, Wang J, Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage. Int J Biochem Cell Biol. 2016 Mar;72:125-134 |
Sox7 SRY (sex determining region Y)-box 7 | |
Results | Reference |
1 | J:333725 Chiang IKN, Graus MS, Kirschnick N, Davidson T, Luu W, Harwood R, Jiang K, Li B, Wong YY, Moustaqil M, Lesieur E, Skoczylas R, Kouskoff V, Kazenwadel J, Arriola-Martinez L, Sierecki E, Gambin Y, Alitalo K, Kiefer F, Harvey NL, Francois M, The blood vasculature instructs lymphatic patterning in a SOX7-dependent manner. EMBO J. 2023 Mar 1;42(5):e109032 |
1 | J:241851 Villani R, Hodgson S, Legrand J, Greaney J, Wong HY, Pichol-Thievend C, Adolphe C, Wainwight B, Francois M, Khosrotehrani K, Dominant-negative Sox18 function inhibits dermal papilla maturation and differentiation in all murine hair types. Development. 2017 May 15;144(10):1887-1895 |
1 | J:187416 Wat MJ, Beck TF, Hernandez-Garcia A, Yu Z, Veenma D, Garcia M, Holder AM, Wat JJ, Chen Y, Mohila CA, Lally KP, Dickinson M, Tibboel D, de Klein A, Lee B, Scott DA, Mouse model reveals the role of SOX7 in the development of congenital diaphragmatic hernia associated with recurrent deletions of 8p23.1. Hum Mol Genet. 2012 Sep 15;21(18):4115-25 |
Sox8 SRY (sex determining region Y)-box 8 | |
Results | Reference |
1 | J:95755 Maka M, Stolt CC, Wegner M, Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect. Dev Biol. 2005 Jan 1;277(1):155-69 |
1 | J:350915 Molin AN, Contentin R, Angelozzi M, Karvande A, Kc R, Haseeb A, Voskamp C, de Charleroy C, Lefebvre V, Skeletal growth is enhanced by a shared role for SOX8 and SOX9 in promoting reserve chondrocyte commitment to columnar proliferation. Proc Natl Acad Sci U S A. 2024 Feb 20;121(8):e2316969121 |
1 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:338174 Reiprich S, Stolt CC, Schreiner S, Parlato R, Wegner M, SoxE proteins are differentially required in mouse adrenal gland development. Mol Biol Cell. 2008 Apr;19(4):1575-86 |
1* | J:84956 Schmidt K, Glaser G, Wernig A, Wegner M, Rosorius O, Sox8 is a specific marker for muscle satellite cells and inhibits myogenesis. J Biol Chem. 2003 Aug 8;278(32):29769-75 |
1 | J:175105 Shen JH, Ingraham HA, Regulation of the orphan nuclear receptor steroidogenic factor 1 by Sox proteins. Mol Endocrinol. 2002 Mar;16(3):529-40 |
1* | J:71578 Sock E, Schmidt K, Hermanns-Borgmeyer I, Bosl MR, Wegner M, Idiopathic weight reduction in mice deficient in the high-mobility-group transcription factor sox8. Mol Cell Biol. 2001 Oct;21(20):6951-9 |
1 | J:98431 Stolt CC, Lommes P, Friedrich RP, Wegner M, Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy. Development. 2004 May;131(10):2349-58 |
1 | J:356085 Wang J, Tian GG, Zheng Z, Li B, Xing Q, Wu J, Comprehensive Transcriptomic Analysis of Mouse Gonadal Development Involving Sexual Differentiation, Meiosis and Gametogenesis. Biol Proced Online. 2019;21:20 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
Sox9 SRY (sex determining region Y)-box 9 (Synonyms: 2010306G03Rik) | |
Results | Reference |
1 | J:346179 Abe S, Nagatomo H, Sasaki H, Ishiuchi T, A histone H3.3K36M mutation in mice causes an imbalance of histone modifications and defects in chondrocyte differentiation. Epigenetics. 2021 Oct;16(10):1123-1134 |
1 | J:219809 Afelik S, Pool B, Schmerr M, Penton C, Jensen J, Wnt7b is required for epithelial progenitor growth and operates during epithelial-to-mesenchymal signaling in pancreatic development. Dev Biol. 2015 Mar 15;399(2):204-17 |
3 | J:166547 Airik R, Trowe MO, Foik A, Farin HF, Petry M, Schuster-Gossler K, Schweizer M, Scherer G, Kist R, Kispert A, Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme. Hum Mol Genet. 2010 Dec 15;19(24):4918-29 |
2 | J:90567 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 2004 May 1;18(9):1072-87 |
1 | J:121946 Akiyama H, Stadler HS, Martin JF, Ishii TM, Beachy PA, Nakamura T, de Crombrugghe B, Misexpression of Sox9 in mouse limb bud mesenchyme induces polydactyly and rescues hypodactyly mice. Matrix Biol. 2007 May;26(4):224-33 |
1* | J:324263 Aksel S, Cao M, Derpinghaus A, Baskin LS, Cunha GR, Ontogeny of mouse Sertoli, Leydig and peritubular myoid cells from embryonic day 10 to adulthood. Differentiation. 2022 Mar 7; |
2 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:307093 Amato CM, Yao HH, Developmental and sexual dimorphic atlas of the prenatal mouse external genitalia at the single-cell level. Proc Natl Acad Sci U S A. 2021 Jun 22;118(25):e2103856118 |
1 | J:275626 Anamthathmakula P, Miryala CSJ, Moreci RS, Kyathanahalli C, Hassan SS, Condon JC, Jeyasuria P, Steroidogenic Factor 1 (Nr5a1) is Required for Sertoli Cell Survival Post Sex Determination. Sci Rep. 2019 Mar 14;9(1):4452 |
1 | J:305792 Ansarullah, Jain C, Far FF, Homberg S, Wissmiller K, von Hahn FG, Raducanu A, Schirge S, Sterr M, Bilekova S, Siehler J, Wiener J, Oppenlander L, Morshedi A, Bastidas-Ponce A, Collden G, Irmler M, Beckers J, Feuchtinger A, Grzybek M, Ahlbrecht C, Feederle R, Plettenburg O, Muller TD, Meier M, Tschop MH, Coskun U, Lickert H, Inceptor counteracts insulin signalling in beta-cells to control glycaemia. Nature. 2021 Feb;590(7845):326-331 |
1 | J:150973 Antoniou A, Raynaud P, Cordi S, Zong Y, Tronche F, Stanger BZ, Jacquemin P, Pierreux CE, Clotman F, Lemaigre FP, Intrahepatic bile ducts develop according to a new mode of tubulogenesis regulated by the transcription factor SOX9. Gastroenterology. 2009 Jun;136(7):2325-33 |
1 | J:284333 Arai HN, Sato F, Yamamoto T, Woltjen K, Kiyonari H, Yoshimoto Y, Shukunami C, Akiyama H, Kist R, Sehara-Fujisawa A, Metalloprotease-Dependent Attenuation of BMP Signaling Restricts Cardiac Neural Crest Cell Fate. Cell Rep. 2019 Oct 15;29(3):603-616.e5 |
1 | J:313612 Arimura N, Okada M, Taya S, Dewa KI, Tsuzuki A, Uetake H, Miyashita S, Hashizume K, Shimaoka K, Egusa S, Nishioka T, Yanagawa Y, Yamakawa K, Inoue YU, Inoue T, Kaibuchi K, Hoshino M, DSCAM regulates delamination of neurons in the developing midbrain. Sci Adv. 2020 Sep;6(36) |
2 | J:337598 Au TYK, Yip RKH, Wynn SL, Tan TY, Fu A, Geng YH, Szeto IYY, Niu B, Yip KY, Cheung MCH, Lovell-Badge R, Cheah KSE, Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog-Wnt signaling, causing campomelia. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2208623119 |
1* | J:316640 Badri MK, Zhang H, Ohyama Y, Venkitapathi S, Alamoudi A, Kamiya N, Takeda H, Ray M, Scott G, Tsuji T, Kunieda T, Mishina Y, Mochida Y, Expression of Evc2 in craniofacial tissues and craniofacial bone defects in Evc2 knockout mouse. Arch Oral Biol. 2016 Aug;68:142-52 |
1 | J:327292 Bakhti M, Bastidas-Ponce A, Tritschler S, Czarnecki O, Tarquis-Medina M, Nedvedova E, Jaki J, Willmann SJ, Scheibner K, Cota P, Salinno C, Boldt K, Horn N, Ueffing M, Burtscher I, Theis FJ, Coskun U, Lickert H, Synaptotagmin-13 orchestrates pancreatic endocrine cell egression and islet morphogenesis. Nat Commun. 2022 Aug 4;13(1):4540 |
1 | J:226612 Bankaitis ED, Bechard ME, Wright CV, Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche. Genes Dev. 2015 Oct 15;29(20):2203-16 |
1 | J:235658 Bechard ME, Bankaitis ED, Hipkens SB, Ustione A, Piston DW, Yang YP, Magnuson MA, Wright CV, Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells. Genes Dev. 2016 Aug 15;30(16):1852-65 |
1 | J:176604 Bell SM, Zhang L, Mendell A, Xu Y, Haitchi HM, Lessard JL, Whitsett JA, Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. Dev Biol. 2011 Oct 1;358(1):79-90 |
1 | J:263981 Benhamouche-Trouillet S, O'Loughlin E, Liu CH, Polacheck W, Fitamant J, McKee M, El-Bardeesy N, Chen CS, McClatchey AI, Proliferation-independent role of NF2 (merlin) in limiting biliary morphogenesis. Development. 2018 Apr 30;145(9):dev162123 |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1 | J:336423 Bottasso-Arias N, Burra K, Sinner D, Riede T, Disruption of BMP4 signaling is associated with laryngeal birth defects in a mouse model. Dev Biol. 2023 May 23;500:10-21 |
1 | J:309359 Brinkmeier ML, Bando H, Camarano AC, Fujio S, Yoshimoto K, de Souza FS, Camper SA, Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. J Clin Invest. 2020 Aug 3;130(8):4501-4515 |
1 | J:307544 Burtscher I, Tarquis-Medina M, Salinno C, Schirge S, Beckenbauer J, Bakhti M, Lickert H, Generation of a Novel Nkx6-1 Venus Fusion Reporter Mouse Line. Int J Mol Sci. 2021 Mar 26;22(7) |
1 | J:313961 Caramello A, Galichet C, Rizzoti K, Lovell-Badge R, Dentate gyrus development requires a cortical hem-derived astrocytic scaffold. Elife. 2021 Jan 4;10:e63904 |
1 | J:177402 Carpentier R, Suner RE, van Hul N, Kopp JL, Beaudry JB, Cordi S, Antoniou A, Raynaud P, Lepreux S, Jacquemin P, Leclercq IA, Sander M, Lemaigre FP, Embryonic ductal plate cells give rise to cholangiocytes, periportal hepatocytes, and adult liver progenitor cells. Gastroenterology. 2011 Oct;141(4):1432-1438.e4 |
1 | J:202949 Chang DR, Martinez Alanis D, Miller RK, Ji H, Akiyama H, McCrea PD, Chen J, Lung epithelial branching program antagonizes alveolar differentiation. Proc Natl Acad Sci U S A. 2013 Nov 5;110(45):18042-51 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1* | J:166517 Chen G, Yang L, Begum S, Xu L, GPR56 is essential for testis development and male fertility in mice. Dev Dyn. 2010 Dec;239(12):3358-67 |
1 | J:190166 Chen JA, Wichterle H, Apoptosis of limb innervating motor neurons and erosion of motor pool identity upon lineage specific dicer inactivation. Front Neurosci. 2012;6:69 |
1* | J:248190 Chen K, Quan H, Chen G, Xiao D, Spatio-temporal expression patterns of Wnt signaling pathway during the development of temporomandibular condylar cartilage. Gene Expr Patterns. 2017 Nov;25-26:149-158 |
1* | J:319765 Chen L, Chen Y, Xu Y, Shen SG, Dai J, Effect of Swell1 on regulating chondrocyte hypertrophy during the condylar osteochondral development process in mice. Biochem Biophys Res Commun. 2022 Jan 29;590:42-48 |
1 | J:251599 Chen W, Chen L, Zhang Z, Meng F, Huang G, Sheng P, Zhang Z, Liao W, MicroRNA-455-3p modulates cartilage development and degeneration through modification of histone H3 acetylation. Biochim Biophys Acta. 2016 Dec;1863(12):2881-2891 |
3* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:317045 Cheng W, Li HL, Xi SY, Zhang XF, Zhu Y, Le Xing, Mo YX, Li MM, Kong FE, Zhu WJ, Chen XG, Cui HQ, Cao ZM, Gong YF, Tang YQ, Zhang Y, Guan XY, Ma NF, Liu M, Growth differentiation factor 1-induced tumour plasticity provides a therapeutic window for immunotherapy in hepatocellular carcinoma. Nat Commun. 2021 Dec 8;12(1):7142 |
1 | J:206944 Clegg JM, Conway CD, Howe KM, Price DJ, Mason JO, Turnbull JE, Basson MA, Pratt T, Heparan sulfotransferases Hs6st1 and Hs2st Keep Erk in check for mouse corpus callosum development. J Neurosci. 2014 Feb 5;34(6):2389-401 |
1* | J:332642 Cohen-Gulkar M, David A, Messika-Gold N, Eshel M, Ovadia S, Zuk-Bar N, Idelson M, Cohen-Tayar Y, Reubinoff B, Ziv T, Shamay M, Elkon R, Ashery-Padan R, The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration. PLoS Biol. 2023 Jan;21(1):e3001924 |
1 | J:346120 Cornejo F, Franchini N, Cortes BI, Elgueta D, Cancino GI, Neural conditional ablation of the protein tyrosine phosphatase receptor Delta PTPRD impairs gliogenesis in the developing mouse brain cortex. Front Cell Dev Biol. 2024;12:1357862 |
1 | J:346123 Darrigrand JF, Salowka A, Torres-Cano A, Tapia-Rojo R, Zhu T, Garcia-Manyes S, Spagnoli FM, Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner. Dev Cell. 2024 Feb 5;59(3):326-338.e5 |
1 | J:220324 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C, Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 1;142(5):871-82 |
1 | J:361670 Defamie V, Aliar K, Sarkar S, Vyas F, Shetty R, Reddy Narala S, Fang H, Saw S, Tharmapalan P, Sanchez O, Knox JJ, Waterhouse PD, Khokha R, Metalloproteinase inhibitors regulate biliary progenitor cells through sDLK1 in organoid models of liver injury. J Clin Invest. 2024 Dec 19;135(3) |
1 | J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109 |
1 | J:160493 Dy P, Smits P, Silvester A, Penzo-Mendez A, Dumitriu B, Han Y, de la Motte CA, Kingsley DM, Lefebvre V, Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. Dev Biol. 2010 May 15;341(2):346-59 |
1* | J:302398 Edelsztein NY, Kashimada K, Schteingart HF, Rey RA, CYP26B1 declines postnatally in Sertoli cells independently of androgen action in the mouse testis. Mol Reprod Dev. 2020 Jan;87(1):66-77 |
1 | J:316977 Endale M, Ahlfeld S, Bao E, Chen X, Green J, Bess Z, Weirauch MT, Xu Y, Perl AK, Temporal, spatial, and phenotypical changes of PDGFRalpha expressing fibroblasts during late lung development. Dev Biol. 2017 May 15;425(2):161-175 |
1 | J:267596 Escot S, Willnow D, Naumann H, Di Francescantonio S, Spagnoli FM, Robo signalling controls pancreatic progenitor identity by regulating Tead transcription factors. Nat Commun. 2018 Nov 30;9(1):5082 |
1 | J:293351 Eyal S, Kult S, Rubin S, Krief S, Felsenthal N, Pineault KM, Leshkowitz D, Salame TM, Addadi Y, Wellik DM, Zelzer E, Bone morphology is regulated modularly by global and regional genetic programs. Development. 2019 Jul 26;146(14):dev167882 |
2 | J:272612 Eyal S, Rubin S, Krief S, Levin L, Zelzer E, Common cellular origin and diverging developmental programs for different sesamoid bones. Development. 2019 Feb 28;146(4):dev167452 |
2 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1 | J:194118 Fantauzzo KA, Kurban M, Levy B, Christiano AM, Trps1 and its target gene Sox9 regulate epithelial proliferation in the developing hair follicle and are associated with hypertrichosis. PLoS Genet. 2012;8(11):e1003002 |
1 | J:292306 Francis R, Guo H, Streutker C, Ahmed M, Yung T, Dirks PB, He HH, Kim TH, Gastrointestinal transcription factors drive lineage-specific developmental programs in organ specification and cancer. Sci Adv. 2019 Dec;5(12):eaax8898 |
1 | J:168727 Furuyama K, Kawaguchi Y, Akiyama H, Horiguchi M, Kodama S, Kuhara T, Hosokawa S, Elbahrawy A, Soeda T, Koizumi M, Masui T, Kawaguchi M, Takaori K, Doi R, Nishi E, Kakinoki R, Deng JM, Behringer RR, Nakamura T, Uemoto S, Continuous cell supply from a Sox9-expressing progenitor zone in adult liver, exocrine pancreas and intestine. Nat Genet. 2011 Jan;43(1):34-41 |
1 | J:339855 Gannoun L, De Schrevel C, Belle M, Dauguet N, Achouri Y, Loriot A, Vanderaa C, Cordi S, Dili A, Heremans Y, Rooman I, Leclercq IA, Jacquemin P, Gatto L, Lemaigre FP, Axon guidance genes control hepatic artery development. Development. 2023 Aug 15;150(16):dev201642 |
1 | J:159978 Gao Z, Kim GH, Mackinnon AC, Flagg AE, Bassett B, Earley JU, Svensson EC, Ets1 is required for proper migration and differentiation of the cardiac neural crest. Development. 2010 May;137(9):1543-51 |
1 | J:152858 Garcia-Ortiz JE, Pelosi E, Omari S, Nedorezov T, Piao Y, Karmazin J, Uda M, Cao A, Cole SW, Forabosco A, Schlessinger D, Ottolenghi C, Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Dev Biol. 2009;9:36 |
1 | J:356109 Ge W, Tan SJ, Wang SH, Li L, Sun XF, Shen W, Wang X, Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development. Theranostics. 2020;10(17):7581-7598 |
1 | J:192856 George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE, Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol. 2012 Dec;32(24):5116-28 |
1 | J:193959 Georgia S, Kanji M, Bhushan A, DNMT1 represses p53 to maintain progenitor cell survival during pancreatic organogenesis. Genes Dev. 2013 Feb 15;27(4):372-7 |
1* | J:260471 Gerhardt B, Leesman L, Burra K, Snowball J, Rosenzweig R, Guzman N, Ambalavanan M, Sinner D, Notum attenuates Wnt/beta-catenin signaling to promote tracheal cartilage patterning. Dev Biol. 2018 Apr 1;436(1):14-27 |
1 | J:189063 Goodnough LH, Chang AT, Treloar C, Yang J, Scacheri PC, Atit RP, Twist1 mediates repression of chondrogenesis by beta-catenin to promote cranial bone progenitor specification. Development. 2012 Dec;139(23):4428-38 |
1 | J:264149 Goto S, Onishi A, Misaki K, Yonemura S, Sugita S, Ito H, Ohigashi Y, Ema M, Sakaguchi H, Nishida K, Takahashi M, Neural retina-specific Aldh1a1 controls dorsal choroidal vascular development via Sox9 expression in retinal pigment epithelial cells. Elife. 2018 Apr 3;7:e32358 |
1 | J:334094 Gu X, Heinrich A, Li SY, DeFalco T, Testicular macrophages are recruited during a narrow fetal time window and promote organ-specific developmental functions. Nat Commun. 2023 Mar 15;14(1):1439 |
1 | J:287857 Gur-Cohen S, Yang H, Baksh SC, Miao Y, Levorse J, Kataru RP, Liu X, de la Cruz-Racelis J, Mehrara BJ, Fuchs E, Stem cell-driven lymphatic remodeling coordinates tissue regeneration. Science. 2019 Dec 6;366(6470):1218-1225 |
1 | J:243204 Han L, Xu J, Grigg E, Slack M, Chaturvedi P, Jiang R, Zorn AM, Osr1 functions downstream of Hedgehog pathway to regulate foregut development. Dev Biol. 2017 Jul 01;427(1):72-83 |
1 | J:309374 Haraguchi R, Kitazawa R, Kitazawa S, Epigenetic regulation of Tbx18 gene expression during endochondral bone formation. Cell Tissue Res. 2015 Feb;359(2):503-512 |
1 | J:342844 Harvey AB, Wolters RA, Deepe RN, Tarolli HG, Drummond JR, Trouten A, Zandi A, Barth JL, Mukherjee R, Romeo MJ, Vaena SG, Tao G, Muise-Helmericks R, Ramos PS, Norris RA, Wessels A, Epicardial deletion of Sox9 leads to myxomatous valve degeneration and identifies Cd109 as a novel gene associated with valve development. J Mol Cell Cardiol. 2023 Nov 5;186:16-30 |
1* | J:231833 Hashimoto R, Hori K, Owa T, Miyashita S, Dewa K, Masuyama N, Sakai K, Hayase Y, Seto Y, Inoue YU, Inoue T, Ichinohe N, Kawaguchi Y, Akiyama H, Koizumi S, Hoshino M, Origins of oligodendrocytes in the cerebellum, whose development is controlled by the transcription factor, Sox9. Mech Dev. 2016 May;140:25-40 |
1* | J:348284 Hassan D, Chen J, CEBPA restricts alveolar type 2 cell plasticity during development and injury-repair. Nat Commun. 2024 May 16;15(1):4148 |
1 | J:159025 Hattori T, Muller C, Gebhard S, Bauer E, Pausch F, Schlund B, Bosl MR, Hess A, Surmann-Schmitt C, von der Mark H, de Crombrugghe B, von der Mark K, SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification. Development. 2010 Mar;137(6):901-11 |
1 | J:354192 He H, Bell SM, Davis AK, Zhao S, Sridharan A, Na CL, Guo M, Xu Y, Snowball J, Swarr DT, Zacharias WJ, Whitsett JA, PRDM3/16 regulate chromatin accessibility required for NKX2-1 mediated alveolar epithelial differentiation and function. Nat Commun. 2024 Sep 16;15(1):8112 |
2 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:267950 Holzman MA, Bergmann JM, Feldman M, Landry-Truchon K, Jeannotte L, Mansfield JH, HOXA5 protein expression and genetic fate mapping show lineage restriction in the developing musculoskeletal system. Int J Dev Biol. 2018;62(11-12):785-796 |
1 | J:237341 Houben A, Kostanova-Poliakova D, Weissenbock M, Graf J, Teufel S, von der Mark K, Hartmann C, beta-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis. Development. 2016 Oct 15;143(20):3826-3838 |
1 | J:255577 Hsu WH, Chen CM, You LR, COUP-TFII is required for morphogenesis of the neural crest-derived tympanic ring. Sci Rep. 2017 Sep 28;7(1):12386 |
1 | J:332137 Hu H, Duan Y, Wang K, Fu H, Liao Y, Wang T, Zhang Z, Kang F, Zhang B, Zhang H, Huo F, Yin Y, Chen G, Hu H, Cai H, Tian W, Li Z, Dental niche cells directly contribute to tooth reconstitution and morphogenesis. Cell Rep. 2022 Dec 6;41(10):111737 |
1 | J:213598 Hu J, Lu J, Lian G, Ferland RJ, Dettenhofer M, Sheen VL, Formin 1 and filamin B physically interact to coordinate chondrocyte proliferation and differentiation in the growth plate. Hum Mol Genet. 2014 Sep 1;23(17):4663-73 |
1 | J:213355 Hu J, Lu J, Lian G, Zhang J, Hecht JL, Sheen VL, Filamin B regulates chondrocyte proliferation and differentiation through Cdk1 signaling. PLoS One. 2014;9(2):e89352 |
1* | J:163555 Huang CC, Yao HH, Inactivation of Dicer1 in Steroidogenic factor 1-positive cells reveals tissue-specific requirement for Dicer1 in adrenal, testis, and ovary. BMC Dev Biol. 2010;10:66 |
1* | J:175121 Huang W, Zhou X, Lefebvre V, de Crombrugghe B, Phosphorylation of SOX9 by cyclic AMP-dependent protein kinase A enhances SOX9's ability to transactivate a Col2a1 chondrocyte-specific enhancer. Mol Cell Biol. 2000 Jun;20(11):4149-58 |
1 | J:160335 Huang X, Liu J, Ketova T, Fleming JT, Grover VK, Cooper MK, Litingtung Y, Chiang C, Transventricular delivery of Sonic hedgehog is essential to cerebellar ventricular zone development. Proc Natl Acad Sci U S A. 2010 May 4;107(18):8422-7 |
1 | J:270532 Iezaki T, Fukasawa K, Horie T, Park G, Robinson S, Nakaya M, Fujita H, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Yoneda Y, Takarada T, Guo XE, Kurose H, Hinoi E, The MAPK Erk5 is necessary for proper skeletogenesis involving a Smurf-Smad-Sox9 molecular axis. Development. 2018 Jul 26;145(14):dev164004 |
1 | J:81856 Ihanamaki T, Saamanen AM, Suominen J, Pelliniemi LJ, Harley V, Vuorio E, Salminen H, Expression of Sox9 and type IIA procollagen during ocular development and aging in transgenic Del1 mice with a mutation in the type II collagen gene. Eur J Ophthalmol. 2002 Nov-Dec;12(6):450-8 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:188056 Jameson SA, Lin YT, Capel B, Testis development requires the repression of Wnt4 by Fgf signaling. Dev Biol. 2012 Oct 1;370(1):24-32 |
1 | J:289708 Jiang X, Yin S, Fan S, Bao J, Jiao Y, Ali A, Iqbal F, Xu J, Zhang Y, Shi Q, Npat-dependent programmed Sertoli cell proliferation is indispensable for testis cord development and germ cell mitotic arrest. FASEB J. 2019 Aug;33(8):9075-9086 |
2 | J:324237 Kajimoto M, Suzuki K, Ueda Y, Fujimoto K, Takeo T, Nakagata N, Hyuga T, Isono K, Yamada G, Androgen/Wnt/beta-catenin signal axis augments cell proliferation of the mouse erectile tissue, corpus cavernosum. Congenit Anom (Kyoto). 2022 May;62(3):123-133 |
1 | J:361142 Ke X, van Soldt B, Vlahos L, Zhou Y, Qian J, George J, Capdevila C, Glass I, Yan K, Califano A, Cardoso WV, Morphogenesis and regeneration share a conserved core transition cell state program that controls lung epithelial cell fate. Dev Cell. 2024 Dec 9; |
1 | J:327969 Khattar D, Fernandes S, Snowball J, Guo M, Gillen MC, Jain SS, Sinner D, Zacharias W, Swarr DT, PI3K signaling specifies proximal-distal fate by driving a developmental gene regulatory network in SOX9+ mouse lung progenitors. Elife. 2022 Aug 17;11:e67954 |
1 | J:356145 Khouri-Farah N, Guo Q, Morgan K, Shin J, Li JYH, Integrated single-cell transcriptomic and epigenetic study of cell state transition and lineage commitment in embryonic mouse cerebellum. Sci Adv. 2022 Apr;8(13):eabl9156 |
1* | J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347 |
1* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
1 | J:299734 Kishimoto K, Furukawa KT, Luz-Madrigal A, Yamaoka A, Matsuoka C, Habu M, Alev C, Zorn AM, Morimoto M, Bidirectional Wnt signaling between endoderm and mesoderm confers tracheal identity in mouse and human cells. Nat Commun. 2020 Aug 27;11(1):4159 |
1 | J:266265 Kishimoto K, Tamura M, Nishita M, Minami Y, Yamaoka A, Abe T, Shigeta M, Morimoto M, Synchronized mesenchymal cell polarization and differentiation shape the formation of the murine trachea and esophagus. Nat Commun. 2018 Jul 19;9(1):2816 |
1 | J:348423 Kitamura A, Yamamoto M, Hirouchi H, Watanabe G, Taniguchi S, Sekiya S, Ishizuka S, Jeong J, Higa K, Yamashita S, Abe S, Downregulation of SOX9 expression in developing entheses adjacent to intramembranous bone. PLoS One. 2024;19(5):e0301080 |
1 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
1 | J:227517 Koizumi M, Oyama K, Yamakami Y, Kida T, Satoh R, Kato S, Hidema S, Oe T, Goto T, Clevers H, Nawa A, Nishimori K, Lgr4 controls specialization of female gonads in mice. Biol Reprod. 2015 Oct;93(4):90 |
2* | J:297658 Kulibin AY, Malolina EA, Formation of the rete testis during mouse embryonic development. Dev Dyn. 2020 Aug 27; |
1 | J:235955 Laitman BM, Asp L, Mariani JN, Zhang J, Liu J, Sawai S, Chapouly C, Horng S, Kramer EG, Mitiku N, Loo H, Burlant N, Pedre X, Hara Y, Nudelman G, Zaslavsky E, Lee YM, Braun DA, Lu QR, Narla G, Raine CS, Friedman SL, Casaccia P, John GR, The Transcriptional Activator Kruppel-like Factor-6 Is Required for CNS Myelination. PLoS Biol. 2016 May;14(5):e1002467 |
3 | J:237343 Laresgoiti U, Nikolic MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL, Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016 Oct 15;143(20):3686-3699 |
1 | J:217604 Lavado A, Ware M, Pare J, Cao X, The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Development. 2014 Nov;141(21):4182-93 |
3 | J:175843 Lee FY, Faivre EJ, Suzawa M, Lontok E, Ebert D, Cai F, Belsham DD, Ingraham HA, Eliminating SF-1 (NR5A1) sumoylation in vivo results in ectopic hedgehog signaling and disruption of endocrine development. Dev Cell. 2011 Aug 16;21(2):315-27 |
1* | J:306217 Lee H, Ko HW, Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development. BMB Rep. 2020 Jul;53(7):367-372 |
1 | J:316483 Leek CC, Soulas JM, Bhattacharya I, Ganji E, Locke RC, Smith MC, Bhavsar JD, Polson SW, Ornitz DM, Killian ML, Deletion of Fibroblast growth factor 9 globally and in skeletal muscle results in enlarged tuberosities at sites of deltoid tendon attachments. Dev Dyn. 2021 Dec;250(12):1778-1795 |
2 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
1 | J:205567 Li K, Leung AW, Guo Q, Yang W, Li JY, Shp2-Dependent ERK Signaling Is Essential for Induction of Bergmann Glia and Foliation of the Cerebellum. J Neurosci. 2014 Jan 15;34(3):922-31 |
1 | J:335070 Li MH, Kuetemeyer JM, Yallowitz AR, Wellik DM, Characterization of a novel Hoxa5eGFP mouse line. Dev Dyn. 2023 Apr;252(4):536-546 |
1 | J:317557 Li X, Liu H, Gu S, Liu C, Sun C, Zheng Y, Chen Y, Replacing Shox2 with human SHOX leads to congenital disc degeneration of the temporomandibular joint in mice. Cell Tissue Res. 2014 Feb;355(2):345-54 |
1 | J:246806 Li Y, Zhang L, Hu Y, Chen M, Han F, Qin Y, Chen M, Cui X, Duo S, Tang F, Gao F, beta-Catenin directs the transformation of testis Sertoli cells to ovarian granulosa-like cells by inducing Foxl2 expression. J Biol Chem. 2017 Oct 27;292(43):17577-17586 |
1* | J:307824 Liu H, Xu J, Lan Y, Lim HW, Jiang R, The Scleraxis Transcription Factor Directly Regulates Multiple Distinct Molecular and Cellular Processes During Early Tendon Cell Differentiation. Front Cell Dev Biol. 2021;9:654397 |
1 | J:315454 Loscertales M, Nicolaou F, Jeanne M, Longoni M, Gould DB, Sun Y, Maalouf FI, Nagy N, Donahoe PK, Type IV collagen drives alveolar epithelial-endothelial association and the morphogenetic movements of septation. BMC Biol. 2016 Jul 13;14:59 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:258790 Lungova V, Verheyden JM, Sun X, Thibeault SL, beta-Catenin signaling is essential for mammalian larynx recanalization and the establishment of vocal fold progenitor cells. Development. 2018 Feb 16;145(4):dev157677 |
1 | J:152843 Luo J, Zhou W, Zhou X, Li D, Weng J, Yi Z, Cho SG, Li C, Yi T, Wu X, Li XY, de Crombrugghe B, Hook M, Liu M, Regulation of bone formation and remodeling by G-protein-coupled receptor 48. Development. 2009 Aug;136(16):2747-56 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1* | J:150757 Mak AC, Szeto IY, Fritzsch B, Cheah KS, Differential and overlapping expression pattern of SOX2 and SOX9 in inner ear development. Gene Expr Patterns. 2009 Sep;9(6):444-53 |
1 | J:193853 Makino Y, Takahashi Y, Tanabe R, Tamamura Y, Watanabe T, Haraikawa M, Hamagaki M, Hata K, Kanno J, Yoneda T, Saga Y, Goseki-Sone M, Kaneko K, Yamaguchi A, Iimura T, Spatiotemporal disorder in the axial skeleton development of the Mesp2-null mouse: a model of spondylocostal dysostosis and spondylothoracic dysostosis. Bone. 2013 Mar;53(1):248-58 |
1* | J:173838 Manuylov NL, Zhou B, Ma Q, Fox SC, Pu WT, Tevosian SG, Conditional ablation of Gata4 and Fog2 genes in mice reveals their distinct roles in mammalian sexual differentiation. Dev Biol. 2011 May 15;353(2):229-41 |
1 | J:239657 Mao Y, Francis-West P, Irvine KD, Fat4/Dchs1 signaling between stromal and cap mesenchyme cells influences nephrogenesis and ureteric bud branching. Development. 2015 Aug 01;142(15):2574-85 |
1* | J:239654 Marongiu M, Marcia L, Pelosi E, Lovicu M, Deiana M, Zhang Y, Puddu A, Loi A, Uda M, Forabosco A, Schlessinger D, Crisponi L, FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice. BMC Dev Biol. 2015 Jul 02;15:27 |
2 | J:202129 Martin E, Caubit X, Airik R, Vola C, Fatmi A, Kispert A, Fasano L, TSHZ3 and SOX9 regulate the timing of smooth muscle cell differentiation in the ureter by reducing myocardin activity. PLoS One. 2013;8(5):e63721 |
1 | J:210514 Martinez P, Ferrara-Romeo I, Flores JM, Blasco MA, Essential role for the TRF2 telomere protein in adult skin homeostasis. Aging Cell. 2014 Aug;13(4):656-68 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:144181 Meng H, Lee VM, Differential expression of sphingosine-1-phosphate receptors 1-5 in the developing nervous system. Dev Dyn. 2009 Feb;238(2):487-500 |
1 | J:149225 Miclea RL, Karperien M, Bosch CA, van der Horst G, van der Valk MA, Kobayashi T, Kronenberg HM, Rawadi G, Akcakaya P, Lowik CW, Fodde R, Wit JM, Robanus-Maandag EC, Adenomatous polyposis coli-mediated control of beta-catenin is essential for both chondrogenic and osteogenic differentiation of skeletal precursors. BMC Dev Biol. 2009;9:26 |
1 | J:205339 Mis EK, Liem KF Jr, Kong Y, Schwartz NB, Domowicz M, Weatherbee SD, Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length. Dev Biol. 2014 Jan 1;385(1):67-82 |
1* | J:46754 Mitsiadis TA, Mucchielli ML, Raffo S, Proust JP, Koopman P, Goridis C, Expression of the transcription factors Otlx2, Barx1 and Sox9 during mouse odontogenesis. Eur J Oral Sci. 1998 Jan;106 Suppl 1:112-6 |
1 | J:225050 Miyabayashi K, Katoh-Fukui Y, Ogawa H, Baba T, Shima Y, Sugiyama N, Kitamura K, Morohashi K, Aristaless related homeobox gene, Arx, is implicated in mouse fetal Leydig cell differentiation possibly through expressing in the progenitor cells. PLoS One. 2013;8(6):e68050 |
1 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1 | J:264719 Moghieb A, Clair G, Mitchell HD, Kitzmiller J, Zink EM, Kim YM, Petyuk V, Shukla A, Moore RJ, Metz TO, Carson J, McDermott JE, Corley RA, Whitsett JA, Ansong C, Time-resolved proteome profiling of normal lung development. Am J Physiol Lung Cell Mol Physiol. 2018 Jul 1;315(1):L11-L24 |
1 | J:350915 Molin AN, Contentin R, Angelozzi M, Karvande A, Kc R, Haseeb A, Voskamp C, de Charleroy C, Lefebvre V, Skeletal growth is enhanced by a shared role for SOX8 and SOX9 in promoting reserve chondrocyte commitment to columnar proliferation. Proc Natl Acad Sci U S A. 2024 Feb 20;121(8):e2316969121 |
1 | J:320686 Molina LM, Zhu J, Li Q, Pradhan-Sundd T, Krutsenko Y, Sayed K, Jenkins N, Vats R, Bhushan B, Ko S, Hu S, Poddar M, Singh S, Tao J, Sundd P, Singhi A, Watkins S, Ma X, Benos PV, Feranchak A, Michalopoulos G, Nejak-Bowen K, Watson A, Bell A, Monga SP, Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors. Cell Rep. 2021 Jul 6;36(1):109310 |
2 | J:318774 Monemdjou R, Vasheghani F, Fahmi H, Perez G, Blati M, Taniguchi N, Lotz M, St-Arnaud R, Pelletier JP, Martel-Pelletier J, Beier F, Kapoor M, Association of cartilage-specific deletion of peroxisome proliferator-activated receptor gamma with abnormal endochondral ossification and impaired cartilage growth and development in a murine model. Arthritis Rheum. 2012 May;64(5):1551-61 |
1 | J:304719 Morcom L, Gobius I, Marsh AP, Suarez R, Lim JW, Bridges C, Ye Y, Fenlon LR, Zagar Y, Douglass AM, Donahoo AL, Fothergill T, Shaikh S, Kozulin P, Edwards TJ, Cooper HM, Sherr EH, Chedotal A, Leventer RJ, Lockhart PJ, Richards LJ, DCC regulates astroglial development essential for telencephalic morphogenesis and corpus callosum formation. Elife. 2021 Apr 19;10:e61769 |
1* | J:324129 Moreci RS, Lechler T, KIF18B is a cell type-specific regulator of spindle orientation in the epidermis. Mol Biol Cell. 2021 Nov 1;32(21):ar29 |
1 | J:324116 Morita R, Sanzen N, Sasaki H, Hayashi T, Umeda M, Yoshimura M, Yamamoto T, Shibata T, Abe T, Kiyonari H, Furuta Y, Nikaido I, Fujiwara H, Tracing the origin of hair follicle stem cells. Nature. 2021 Jun;594(7864):547-552 |
3 | J:205660 Nakamura Y, Yamamoto K, He X, Otsuki B, Kim Y, Murao H, Soeda T, Tsumaki N, Deng JM, Zhang Z, Behringer RR, Crombrugghe Bd, Postlethwait JH, Warman ML, Nakamura T, Akiyama H, Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25. Nat Commun. 2011;2:251 |
1 | J:85095 Nakashima K, de Crombrugghe B, Transcriptional mechanisms in osteoblast differentiation and bone formation. Trends Genet. 2003 Aug;19(8):458-66 |
1* | J:74344 Nakashima K, Zhou X, Kunkel G, Zhang Z, Deng JM, Behringer RR, de Crombrugghe B, The novel zinc finger-containing transcription factor osterix is required for osteoblast differentiation and bone formation. Cell. 2002 Jan 11;108(1):17-29 |
1 | J:309384 Neirijnck Y, Reginensi A, Renkema KY, Massa F, Kozlov VM, Dhib H, Bongers EMHF, Feitz WF, van Eerde AM, Lefebvre V, Knoers NVAM, Tabatabaei M, Schulz H, McNeill H, Schaefer F, Wegner M, Sock E, Schedl A, Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT). Kidney Int. 2018 May;93(5):1142-1153 |
1* | J:148405 Nel-Themaat L, Vadakkan TJ, Wang Y, Dickinson ME, Akiyama H, Behringer RR, Morphometric analysis of testis cord formation in Sox9-EGFP mice. Dev Dyn. 2009 May;238(5):1100-10 |
1* | J:38926 Ng LJ, Wheatley S, Muscat GE, Conway-Campbell J, Bowles J, Wright E , Bell DM , Tam PP , Cheah KS , Koopman P, SOX9 binds DNA, activates transcription, and coexpresses with type II collagen during chondrogenesis in the mouse. Dev Biol. 1997 Mar 1;183(1):108-21 |
1 | J:253982 Norlin S, Parekh V, Edlund H, The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival. Development. 2018 Jan 3;145(1):dev154468 |
2 | J:207286 Nowak JA, Polak L, Pasolli HA, Fuchs E, Hair follicle stem cells are specified and function in early skin morphogenesis. Cell Stem Cell. 2008 Jul 3;3(1):33-43 |
1 | J:242339 Ohayon D, Garces A, Joly W, Soukkarieh C, Takagi T, Sabourin JC, Agius E, Darling DS, De Santa Barbara P, Higashi Y, Stolt CC, Hugnot JP, Richardson WD, Carroll P, Pattyn A, Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Cell Rep. 2016 Nov 01;17(6):1473-1481 |
1 | J:97215 Okubo T, Knoepfler PS, Eisenman RN, Hogan BL, Nmyc plays an essential role during lung development as a dosage-sensitive regulator of progenitor cell proliferation and differentiation. Development. 2005 Mar;132(6):1363-74 |
1 | J:171374 Osorio KM, Lilja KC, Tumbar T, Runx1 modulates adult hair follicle stem cell emergence and maintenance from distinct embryonic skin compartments. J Cell Biol. 2011 Apr 4;193(1):235-50 |
1 | J:257543 Owa T, Taya S, Miyashita S, Yamashita M, Adachi T, Yamada K, Yokoyama M, Aida S, Nishioka T, Inoue YU, Goitsuka R, Nakamura T, Inoue T, Kaibuchi K, Hoshino M, Meis1 Coordinates Cerebellar Granule Cell Development by Regulating Pax6 Transcription, BMP Signaling and Atoh1 Degradation. J Neurosci. 2018 Jan 31;38(5):1277-1294 |
1* | J:265842 Palagano E, Zuccarini G, Prontera P, Borgatti R, Stangoni G, Elisei S, Mantero S, Menale C, Forlino A, Uva P, Oppo M, Vezzoni P, Villa A, Merlo GR, Sobacchi C, Mutations in the Neuroblastoma Amplified Sequence gene in a family affected by Acrofrontofacionasal Dysostosis type 1. Bone. 2018 Sep;114:125-136 |
1 | J:84742 Pavlov MI, Sautier JM, Oboeuf M, Asselin A, Berdal A, Chondrogenic differentiation during midfacial development in the mouse: in vivo and in vitro studies. Biol Cell. 2003;95(2):75-86 |
1 | J:95910 Perl AK, Kist R, Shan Z, Scherer G, Whitsett JA, Normal lung development and function after Sox9 inactivation in the respiratory epithelium. Genesis. 2005 Jan;41(1):23-32 |
1 | J:191071 Petzold KM, Naumann H, Spagnoli FM, Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas. Development. 2013 Jan 1;140(1):126-35 |
1 | J:197599 Pitetti JL, Calvel P, Romero Y, Conne B, Truong V, Papaioannou MD, Schaad O, Docquier M, Herrera PL, Wilhelm D, Nef S, Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice. PLoS Genet. 2013;9(1):e1003160 |
2 | J:187354 Poche RA, Furuta Y, Chaboissier MC, Schedl A, Behringer RR, Sox9 is expressed in mouse multipotent retinal progenitor cells and functions in Muller glial cell development. J Comp Neurol. 2008 Sep 20;510(3):237-50 |
1 | J:71330 Pompolo S, Harley VR, Localisation of the SRY-related HMG box protein, SOX9, in rodent brain. Brain Res. 2001 Jul 6;906(1-2):143-8 |
1 | J:221833 Prakash A, Udager AM, Saenz DA, Gumucio DL, Roles for Nkx2-5 and Gata3 in the ontogeny of the murine smooth muscle gastric ligaments. Am J Physiol Gastrointest Liver Physiol. 2014 Aug 15;307(4):G430-6 |
1* | J:199462 Probst S, Zeller R, Zuniga A, The hedgehog target Vlk genetically interacts with Gli3 to regulate chondrocyte differentiation during mouse long bone development. Differentiation. 2013 Apr-Jun;85(4-5):121-30 |
1* | J:326026 Prokopuk L, Jarred EG, Blucher RO, McLaughlin EA, Stringer JM, Western PS, An essential role for Polycomb Repressive Complex 2 in the mouse ovary. Reproduction. 2022 Feb 17;163(3):167-182 |
1 | J:128917 Provot S, Nachtrab G, Paruch J, Chen AP, Silva A, Kronenberg HM, A-raf and B-raf are dispensable for normal endochondral bone development, and parathyroid hormone-related peptide suppresses extracellular signal-regulated kinase activation in hypertrophic chondrocytes. Mol Cell Biol. 2008 Jan;28(1):344-57 |
1* | J:356701 Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD, Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr;91(4):387-93 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1 | J:281274 Qu X, Violette K, Sewell-Loftin MK, Soslow J, Saint-Jean L, Hinton RB, Merryman WD, Baldwin HS, Loss of flow responsive Tie1 results in ImpairedAortic valve remodeling. Dev Biol. 2019 Nov 1;455(1):73-84 |
1 | J:223566 Raft S, Coate TM, Kelley MW, Crenshaw EB 3rd, Wu DK, Pou3f4-mediated regulation of ephrin-b2 controls temporal bone development in the mouse. PLoS One. 2014;9(10):e109043 |
1 | J:282858 Ramachandran J, Liu Z, Gray RS, Vokes SA, PRMT5 is necessary to form distinct cartilage identities in the knee and long bone. Dev Biol. 2019 Dec 15;456(2):154-163 |
1 | J:168845 Reginensi A, Clarkson M, Neirijnck Y, Lu B, Ohyama T, Groves AK, Sock E, Wegner M, Costantini F, Chaboissier MC, Schedl A, SOX9 controls epithelial branching by activating RET effector genes during kidney development. Hum Mol Genet. 2011 Mar 15;20(6):1143-53 |
1 | J:202984 Rockich BE, Hrycaj SM, Shih HP, Nagy MS, Ferguson MA, Kopp JL, Sander M, Wellik DM, Spence JR, Sox9 plays multiple roles in the lung epithelium during branching morphogenesis. Proc Natl Acad Sci U S A. 2013 Nov 19;110(47):E4456-64 |
1 | J:165741 Rojas A, Schachterle W, Xu SM, Martin F, Black BL, Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer. Dev Biol. 2010 Oct 15;346(2):346-55 |
1 | J:340421 Ruscitto A, Chen P, Tosa I, Wang Z, Zhou G, Safina I, Wei R, Morel MM, Koch A, Forman M, Reeve G, Lecholop MK, Wilson M, Bonthius D, Chen M, Ono M, Wang TC, Yao H, Embree MC, Lgr5-expressing secretory cells form a Wnt inhibitory niche in cartilage critical for chondrocyte identity. Cell Stem Cell. 2023 Sep 7;30(9):1179-1198.e7 |
1 | J:334500 Ruthig VA, Yokonishi T, Friedersdorf MB, Batchvarova S, Hardy J, Garness JA, Keene JD, Capel B, A transgenic DND1GFP fusion allele reports in vivo expression and RNA-binding targets in undifferentiated mouse germ cells. Biol Reprod. 2021 Apr 1;104(4):861-874 |
1 | J:327338 Sartoretti MM, Campetella CA, Lanuza GM, Dbx1 controls the development of astrocytes of the intermediate spinal cord by modulating Notch signaling. Development. 2022 Aug 1;149(15):dev200750 |
1 | J:345231 Satta JP, Lan Q, Taketo MM, Mikkola ML, Stabilization of Epithelial beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis. J Invest Dermatol. 2023 Dec 28; |
1* | J:207837 Schmid R, Bosserhoff AK, Redundancy in regulation of chondrogenesis in MIA/CD-RAP-deficient mice. Mech Dev. 2014 Feb;131:24-34 |
2 | J:191793 Schnatwinkel C, Niswander L, Nubp1 is required for lung branching morphogenesis and distal progenitor cell survival in mice. PLoS One. 2012;7(9):e44871 |
1* | J:281428 Schneider AJ, Gawdzik J, Vezina CM, Baker TR, Peterson RE, Sox9 in mouse urogenital sinus epithelium mediates elongation of prostatic buds and expression of genes involved in epithelial cell migration. Gene Expr Patterns. 2019 Oct 25;34:119075 |
1 | J:175105 Shen JH, Ingraham HA, Regulation of the orphan nuclear receptor steroidogenic factor 1 by Sox proteins. Mol Endocrinol. 2002 Mar;16(3):529-40 |
1 | J:119736 Shiota M, Heike T, Haruyama M, Baba S, Tsuchiya A, Fujino H, Kobayashi H, Kato T, Umeda K, Yoshimoto M, Nakahata T, Isolation and characterization of bone marrow-derived mesenchymal progenitor cells with myogenic and neuronal properties. Exp Cell Res. 2007 Mar 10;313(5):1008-23 |
1 | J:238111 Shirokova V, Biggs LC, Jussila M, Ohyama T, Groves AK, Mikkola ML, Foxi3 Deficiency Compromises Hair Follicle Stem Cell Specification and Activation. Stem Cells. 2016 Jul;34(7):1896-908 |
2 | J:187998 Shung CY, Ota S, Zhou ZQ, Keene DR, Hurlin PJ, Disruption of a Sox9-beta-catenin circuit by mutant Fgfr3 in thanatophoric dysplasia type II. Hum Mol Genet. 2012 Nov 1;21(21):4628-44 |
1 | J:95959 Smith N, Dong Y, Lian JB, Pratap J, Kingsley PD, van Wijnen AJ, Stein JL, Schwarz EM, O'keefe RJ, Stein GS, Drissi MH, Overlapping expression of Runx1(Cbfa2) and Runx2(Cbfa1) transcription factors supports cooperative induction of skeletal development. J Cell Physiol. 2005 Apr;203(1):133-43 |
1* | J:80666 Smits P, Li P, Mandel J, Zhang Z, Deng JM, Behringer RR, de Croumbrugghe B, Lefebvre V, The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001 Aug;1(2):277-90 |
1 | J:217677 Snitow ME, Li S, Morley MP, Rathi K, Lu MM, Kadzik RS, Stewart KM, Morrisey EE, Ezh2 represses the basal cell lineage during lung endoderm development. Development. 2015 Jan 1;142(1):108-17 |
1 | J:156016 Solar M, Cardalda C, Houbracken I, Martin M, Maestro MA, De Medts N, Xu X, Grau V, Heimberg H, Bouwens L, Ferrer J, Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth. Dev Cell. 2009 Dec;17(6):849-60 |
1 | J:317562 Sono T, Akiyama H, Miura S, Deng JM, Shukunami C, Hiraki Y, Tsushima Y, Azuma Y, Behringer RR, Matsuda S, THRAP3 interacts with and inhibits the transcriptional activity of SOX9 during chondrogenesis. J Bone Miner Metab. 2018 Jul;36(4):410-419 |
1 | J:124088 Soung do Y, Dong Y, Wang Y, Zuscik MJ, Schwarz EM, O'Keefe RJ, Drissi H, Runx3/AML2/Cbfa3 regulates early and late chondrocyte differentiation. J Bone Miner Res. 2007 Aug;22(8):1260-70 |
1 | J:134924 Spagnoli A, O'Rear L, Chandler RL, Granero-Molto F, Mortlock DP, Gorska AE, Weis JA, Longobardi L, Chytil A, Shimer K, Moses HL, TGF-beta signaling is essential for joint morphogenesis. J Cell Biol. 2007 Jun 18;177(6):1105-17 |
1* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1 | J:84301 Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M, The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 2003 Jul 1;17(13):1677-89 |
1 | J:275375 Sun S, Zhu XJ, Huang H, Guo W, Tang T, Xie B, Xu X, Zhang Z, Shen Y, Dai ZM, Qiu M, WNT signaling represses astrogliogenesis via Ngn2-dependent direct suppression of astrocyte gene expression. Glia. 2019 Jul;67(7):1333-1343 |
1 | J:351035 Tan Z, Chen P, Dong X, Guo S, Leung VYL, Cheung JPY, Chan D, Richardson SM, Hoyland JA, To MKT, Cheah KSE, Progenitor-like cells contributing to cellular heterogeneity in the nucleus pulposus are lost in intervertebral disc degeneration. Cell Rep. 2024 Jun 25;43(6):114342 |
1 | J:135788 Thomsen MK, Butler CM, Shen MM, Swain A, Sox9 is required for prostate development. Dev Biol. 2008 Apr 15;316(2):302-11 |
1 | J:171513 Tian Y, Zhang Y, Hurd L, Hannenhalli S, Liu F, Lu MM, Morrisey EE, Regulation of lung endoderm progenitor cell behavior by miR302/367. Development. 2011 Apr;138(7):1235-45 |
1 | J:112372 Tsumaki N, Nakase T, Miyaji T, Kakiuchi M, Kimura T, Ochi T, Yoshikawa H, Bone morphogenetic protein signals are required for cartilage formation and differently regulate joint development during skeletogenesis. J Bone Miner Res. 2002 May;17(5):898-906 |
1 | J:228275 Udager AM, Prakash A, Saenz DA, Schinke M, Moriguchi T, Jay PY, Lim KC, Engel JD, Gumucio DL, Proper development of the outer longitudinal smooth muscle of the mouse pylorus requires Nkx2-5 and Gata3. Gastroenterology. 2014 Jan;146(1):157-65.e10 |
1* | J:209518 Ushijima T, Okazaki K, Tsushima H, Iwamoto Y, CCAAT/enhancer-binding protein beta regulates the repression of type II collagen expression during the differentiation from proliferative to hypertrophic chondrocytes. J Biol Chem. 2014 Jan 31;289(5):2852-63 |
1 | J:266598 Ustiyan V, Bolte C, Zhang Y, Han L, Xu Y, Yutzey KE, Zorn AM, Kalin TV, Shannon JM, Kalinichenko VV, FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme. Dev Biol. 2018 Nov 1;443(1):50-63 |
1 | J:112002 van der Weyden L, Wei L, Luo J, Yang X, Birk DE, Adams DJ, Bradley A, Chen Q, Functional knockout of the matrilin-3 gene causes premature chondrocyte maturation to hypertrophy and increases bone mineral density and osteoarthritis. Am J Pathol. 2006 Aug;169(2):515-27 |
1 | J:231427 Vanderpool C, Sparks EE, Huppert KA, Gannon M, Means AL, Huppert SS, Genetic interactions between hepatocyte nuclear factor-6 and Notch signaling regulate mouse intrahepatic bile duct development in vivo. Hepatology. 2012 Jan;55(1):233-43 |
1 | J:340444 Veithen M, Huyghe A, Van Den Ackerveken P, Fukada SI, Kokubo H, Breuskin I, Nguyen L, Delacroix L, Malgrange B, Sox9 Inhibits Cochlear Hair Cell Fate by Upregulating Hey1 and HeyL Antagonists of Atoh1. Cells. 2023 Aug 25;12(17) |
1 | J:308907 Verheijen N, Suttorp CM, van Rheden REM, Regan RF, Helmich MPAC, Kuijpers-Jagtman AM, Wagener FADTG, CXCL12-CXCR4 Interplay Facilitates Palatal Osteogenesis in Mice. Front Cell Dev Biol. 2020;8:771 |
2 | J:214986 Walker EM, Thompson CA, Battle MA, GATA4 and GATA6 regulate intestinal epithelial cytodifferentiation during development. Dev Biol. 2014 Aug 15;392(2):283-94 |
1 | J:338452 Wang D, Li H, Chandel NS, Dou Y, Yi R, MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters. Nat Commun. 2023 Jul 21;14(1):4404 |
1 | J:356085 Wang J, Tian GG, Zheng Z, Li B, Xing Q, Wu J, Comprehensive Transcriptomic Analysis of Mouse Gonadal Development Involving Sexual Differentiation, Meiosis and Gametogenesis. Biol Proced Online. 2019;21:20 |
1 | J:316121 Wang JR, Wang CJ, Xu CY, Wu XK, Hong D, Shi W, Gong Y, Chen HX, Long F, Wu XM, Signaling Cascades Governing Cdc42-Mediated Chondrogenic Differentiation and Mensenchymal Condensation. Genetics. 2016 Mar;202(3):1055-69 |
1 | J:101174 Wang Y, Xiao R, Yang F, Karim BO, Iacovelli AJ, Cai J, Lerner CP, Richtsmeier JT, Leszl JM, Hill CA, Yu K, Ornitz DM, Elisseeff J, Huso DL, Jabs EW, Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse. Development. 2005 Aug;132(15):3537-48 |
1 | J:286995 Wang YQ, Cheng JM, Wen Q, Tang JX, Li J, Chen SR, Liu YX, An exploration of the role of Sertoli cells on fetal testis development using cell ablation strategy. Mol Reprod Dev. 2020 Feb;87(2):223-230 |
1* | J:104307 Wilson ME, Yang KY, Kalousova A, Lau J, Kosaka Y, Lynn FC, Wang J, Mrejen C, Episkopou V, Clevers HC, German MS, The HMG Box Transcription Factor Sox4 Contributes to the Development of the Endocrine Pancreas. Diabetes. 2005 Dec;54(12):3402-9 |
1* | J:96928 Wilson MJ, Jeyasuria P, Parker KL, Koopman P, The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development. J Biol Chem. 2005 Feb 18;280(7):5917-23 |
1 | J:301042 Wright D, Kiso M, Saga Y, Genetic and structural analysis of the in vivo functional redundancy between murine NANOS2 and NANOS3. Development. 2021 Jan 11;148(1):dev191916 |
2 | J:224370 Wu C, Jiao H, Lai Y, Zheng W, Chen K, Qu H, Deng W, Song P, Zhu K, Cao H, Galson DL, Fan J, Im HJ, Liu Y, Chen J, Chen D, Xiao G, Kindlin-2 controls TGF-beta signalling and Sox9 expression to regulate chondrogenesis. Nat Commun. 2015;6:7531 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1 | J:362739 Wu Y, Qin K, Xu Y, Rajhans S, Vo T, Lopez KM, Liu J, Nipper MH, Deng J, Yin X, Ramjit LR, Ye Z, Luan Y, Arda HE, Wang P, Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation. Elife. 2024 Jul 25;13 |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
1 | J:331058 Xu J, Liu H, Lan Y, Jiang R, The transcription factors Foxf1 and Foxf2 integrate the SHH, HGF and TGFbeta signaling pathways to drive tongue organogenesis. Development. 2022 Nov 1;149(21):dev200667 |
1 | J:352714 Yang J, Zhang YN, Wang RX, Hao CZ, Qiu Y, Chi H, Luan WS, Tang H, Zhang XJ, Sun X, Sheps JA, Ling V, Cao M, Wang JS, ZFYVE19 deficiency: a ciliopathy involving failure of cell division, with cell death. J Med Genet. 2024 Jul 19;61(8):750-758 |
1 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
1 | J:320311 Yang L, Gu S, Ye W, Song Y, Chen Y, Augmented Indian hedgehog signaling in cranial neural crest cells leads to craniofacial abnormalities and dysplastic temporomandibular joint in mice. Cell Tissue Res. 2016 Apr;364(1):105-15 |
1 | J:141958 Yang SH, Andl T, Grachtchouk V, Wang A, Liu J, Syu LJ, Ferris J, Wang TS, Glick AB, Millar SE, Dlugosz AA, Pathological responses to oncogenic Hedgehog signaling in skin are dependent on canonical Wnt/beta-catenin signaling. Nat Genet. 2008 Sep 1;40(9):1130-5 |
2* | J:254619 Yang ZC, Li D, Feng S, Sui XD, Chen Z, Zhang L, Spatial and temporal expression of Sox9 during murine incisor development. J Mol Histol. 2017 Aug;48(4):321-327 |
2 | J:296772 Yin W, Kim HT, Wang S, Gunawan F, Li R, Buettner C, Grohmann B, Sengle G, Sinner D, Offermanns S, Stainier DYR, Fibrillin-2 is a key mediator of smooth muscle extracellular matrix homeostasis during mouse tracheal tubulogenesis. Eur Respir J. 2019 Mar;53(3) |
1 | J:266389 Yin W, Kim HT, Wang S, Gunawan F, Wang L, Kishimoto K, Zhong H, Roman D, Preussner J, Guenther S, Graef V, Buettner C, Grohmann B, Looso M, Morimoto M, Mardon G, Offermanns S, Stainier DYR, The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis. Nat Commun. 2018 Jul 19;9(1):2815 |
1 | J:360708 Yoshida S, Kawamura A, Aoki K, Wiriyasermkul P, Sugimoto S, Tomiyoshi J, Tajima A, Ishida Y, Katoh Y, Tsukada T, Tsuneoka Y, Yamada K, Nagamori S, Nakayama K, Yoshida K, Positive regulation of Hedgehog signaling via phosphorylation of GLI2/GLI3 by DYRK2 kinase. Proc Natl Acad Sci U S A. 2024 Jul 9;121(28):e2320070121 |
1 | J:331689 Zhang CH, Gao Y, Hung HH, Zhuo Z, Grodzinsky AJ, Lassar AB, Creb5 coordinates synovial joint formation with the genesis of articular cartilage. Nat Commun. 2022 Nov 26;13(1):7295 |
1 | J:332095 Zhang K, Yao E, Chuang E, Chen B, Chuang EY, Chuang PT, mTORC1 signaling facilitates differential stem cell differentiation to shape the developing murine lung and is associated with mitochondrial capacity. Nat Commun. 2022 Nov 25;13(1):7252 |
1 | J:220734 Zhang L, Chen M, Wen Q, Li Y, Wang Y, Wang Y, Qin Y, Cui X, Yang L, Huff V, Gao F, Reprogramming of Sertoli cells to fetal-like Leydig cells by Wt1 ablation. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4003-8 |
2* | J:317374 Zhang M, Lu Q, Miller AH, Barnthouse NC, Wang J, Dynamic epigenetic mechanisms regulate age-dependent SOX9 expression in mouse articular cartilage. Int J Biochem Cell Biol. 2016 Mar;72:125-134 |
1 | J:202210 Zhang X, Ting K, Pathmanathan D, Ko T, Chen W, Chen F, Lee H, James AW, Siu RK, Shen J, Culiat CT, Soo C, Calvarial cleidocraniodysplasia-like defects with ENU-induced Nell-1 deficiency. J Craniofac Surg. 2012 Jan;23(1):61-6 |
1 | J:292430 Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, Zhang X, Zhou Y, Yadav PS, Lin J, Wu N, Zhao L, Huang D, Zhou S, Su P, Yang Y, Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ss-catenin. Elife. 2020 Mar 18;9:e52779 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Sox10 SRY (sex determining region Y)-box 10 (Synonyms: gt, Sox21) | |
Results | Reference |
1* | J:348861 Aberle T, Walter A, Piefke S, Hillgartner S, Wust HM, Wegner M, Kuspert M, Sox10 Activity and the Timing of Schwann Cell Differentiation Are Controlled by a Tle4-Dependent Negative Feedback Loop. Int J Mol Sci. 2024 May 11;25(10) |
1* | J:130196 Alfonsi F, Filippi P, Salaun D, deLapeyriere O, Durbec P, LIFR beta plays a major role in neuronal identity determination and glial differentiation in the mouse facial nucleus. Dev Biol. 2008 Jan 1;313(1):267-78 |
1 | J:230341 Aoki H, Hara A, Kunisada T, White spotting phenotype induced by targeted REST disruption during neural crest specification to a melanocyte cell lineage. Genes Cells. 2015 May;20(5):439-49 |
2* | J:199435 Barraud P, St John JA, Stolt CC, Wegner M, Baker CV, Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Biol Open. 2013 Jul 15;2(7):750-9 |
1 | J:218900 Bischof M, Weider M, Kuspert M, Nave KA, Wegner M, Brg1-dependent chromatin remodelling is not essentially required during oligodendroglial differentiation. J Neurosci. 2015 Jan 7;35(1):21-35 |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
2 | J:154462 Breuskin I, Bodson M, Thelen N, Thiry M, Borgs L, Nguyen L, Lefebvre PP, Malgrange B, Sox10 promotes the survival of cochlear progenitors during the establishment of the organ of Corti. Dev Biol. 2009 Nov 15;335(2):327-39 |
1 | J:179898 Coate TM, Raft S, Zhao X, Ryan AK, Crenshaw EB 3rd, Kelley MW, Otic Mesenchyme Cells Regulate Spiral Ganglion Axon Fasciculation through a Pou3f4/EphA4 Signaling Pathway. Neuron. 2012 Jan 12;73(1):49-63 |
1 | J:212081 Dai ZM, Sun S, Wang C, Huang H, Hu X, Zhang Z, Lu QR, Qiu M, Stage-specific regulation of oligodendrocyte development by Wnt/beta-catenin signaling. J Neurosci. 2014 Jun 18;34(25):8467-73 |
1 | J:314408 Dravis C, Spike BT, Harrell JC, Johns C, Trejo CL, Southard-Smith EM, Perou CM, Wahl GM, Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells. Cell Rep. 2015 Sep 29;12(12):2035-48 |
2 | J:162692 Finzsch M, Schreiner S, Kichko T, Reeh P, Tamm ER, Bosl MR, Meijer D, Wegner M, Sox10 is required for Schwann cell identity and progression beyond the immature Schwann cell stage. J Cell Biol. 2010 May 17;189(4):701-12 |
1 | J:96824 Friedrich RP, Schlierf B, Tamm ER, Bosl MR, Wegner M, The class III POU domain protein Brn-1 can fully replace the related Oct-6 during schwann cell development and myelination. Mol Cell Biol. 2005 Mar;25(5):1821-9 |
1 | J:171201 Furusho M, Kaga Y, Ishii A, Hebert JM, Bansal R, Fibroblast growth factor signaling is required for the generation of oligodendrocyte progenitors from the embryonic forebrain. J Neurosci. 2011 Mar 30;31(13):5055-66 |
1 | J:288683 Gacem N, Kavo A, Zerad L, Richard L, Mathis S, Kapur RP, Parisot M, Amiel J, Dufour S, de la Grange P, Pingault V, Vallat JM, Bondurand N, ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. Nat Commun. 2020 Jan 10;11(1):198 |
1 | J:219427 Glasgow SM, Zhu W, Stolt CC, Huang TW, Chen F, LoTurco JJ, Neul JL, Wegner M, Mohila C, Deneen B, Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subtypes. Nat Neurosci. 2014 Oct;17(10):1322-9 |
1 | J:196579 Gonsalvez DG, Cane KN, Landman KA, Enomoto H, Young HM, Anderson CR, Proliferation and cell cycle dynamics in the developing stellate ganglion. J Neurosci. 2013 Apr 3;33(14):5969-79 |
1 | J:293063 Hamashima T, Ishii Y, Nguyen LQ, Okuno N, Sang Y, Matsushima T, Kurashige Y, Takebayashi H, Mori H, Fujimori T, Yamamoto S, Sasahara M, Oligodendrogenesis and Myelin Formation in the Forebrain Require Platelet-derived Growth Factor Receptor-alpha. Neuroscience. 2020 Jun 1;436:11-26 |
1* | J:269500 Hao MM, Capoccia E, Cirillo C, Boesmans W, Vanden Berghe P, Arundic Acid Prevents Developmental Upregulation of S100B Expression and Inhibits Enteric Glial Development. Front Cell Neurosci. 2017;11:42 |
1 | J:306265 Hao MM, Fung C, Boesmans W, Lowette K, Tack J, Vanden Berghe P, Development of the intrinsic innervation of the small bowel mucosa and villi. Am J Physiol Gastrointest Liver Physiol. 2020 Jan 1;318(1):G53-G65 |
1* | J:202344 Lesko MH, Driskell RR, Kretzschmar K, Goldie SJ, Watt FM, Sox2 modulates the function of two distinct cell lineages in mouse skin. Dev Biol. 2013 Oct 1;382(1):15-26 |
1 | J:361546 Li J, Yang F, Tian Y, Wang Z, Qi D, Yang Z, Song J, Ding J, Wang X, Zhang Z, Lateral/caudal ganglionic eminence makes limited contribution to cortical oligodendrocytes. Elife. 2024 Sep 11;13 |
2 | J:95755 Maka M, Stolt CC, Wegner M, Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect. Dev Biol. 2005 Jan 1;277(1):155-69 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:298989 Mertelmeyer S, Weider M, Baroti T, Reiprich S, Frob F, Stolt CC, Wagner KU, Wegner M, The transcription factor Sox10 is an essential determinant of branching morphogenesis and involution in the mouse mammary gland. Sci Rep. 2020 Oct 20;10(1):17807 |
1 | J:182762 Mundell NA, Plank JL, LeGrone AW, Frist AY, Zhu L, Shin MK, Southard-Smith EM, Labosky PA, Enteric nervous system specific deletion of Foxd3 disrupts glial cell differentiation and activates compensatory enteric progenitors. Dev Biol. 2012 Mar 15;363(2):373-87 |
1 | J:277848 Ohayon D, Escalas N, Cochard P, Glise B, Danesin C, Soula C, Sulfatase 2 promotes generation of a spinal cord astrocyte subtype that stands out through the expression of Olig2. Glia. 2019 Aug;67(8):1478-1495 |
1 | J:242339 Ohayon D, Garces A, Joly W, Soukkarieh C, Takagi T, Sabourin JC, Agius E, Darling DS, De Santa Barbara P, Higashi Y, Stolt CC, Hugnot JP, Richardson WD, Carroll P, Pattyn A, Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Cell Rep. 2016 Nov 01;17(6):1473-1481 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:321441 Polanetzki V, Frob F, Baroti T, Schimmel M, Tamm ER, Wegner M, Role of the Pbrm1 subunit and the PBAF complex in Schwann cell development. Sci Rep. 2022 Feb 16;12(1):2651 |
1 | J:122531 Que J, Okubo T, Goldenring JR, Nam KT, Kurotani R, Morrisey EE, Taranova O, Pevny LH, Hogan BL, Multiple dose-dependent roles for Sox2 in the patterning and differentiation of anterior foregut endoderm. Development. 2007 Jul;134(13):2521-31 |
1 | J:313294 Raucci F, Tiong JD, Wray S, P75 nerve growth factor receptors modulate development of GnRH neurons and olfactory ensheating cells. Front Neurosci. 2013;7:262 |
1* | J:268254 Rich CA, Perera SN, Andratschke J, Stolt CC, Buehler DP, Southard-Smith EM, Wegner M, Britsch S, Baker CVH, Olfactory ensheathing cells abutting the embryonic olfactory bulb express Frzb, whose deletion disrupts olfactory axon targeting. Glia. 2018 Dec;66(12):2617-2631 |
1 | J:165741 Rojas A, Schachterle W, Xu SM, Martin F, Black BL, Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer. Dev Biol. 2010 Oct 15;346(2):346-55 |
1 | J:345231 Satta JP, Lan Q, Taketo MM, Mikkola ML, Stabilization of Epithelial beta-Catenin Compromises Mammary Cell Fate Acquisition and Branching Morphogenesis. J Invest Dermatol. 2023 Dec 28; |
1 | J:173638 Schmidt M, Huber L, Majdazari A, Schutz G, Williams T, Rohrer H, The transcription factors AP-2beta and AP-2alpha are required for survival of sympathetic progenitors and differentiated sympathetic neurons. Dev Biol. 2011 Jul 1;355(1):89-100 |
1* | J:194281 Silver DL, Leeds KE, Hwang HW, Miller EE, Pavan WJ, The EJC component Magoh regulates proliferation and expansion of neural crest-derived melanocytes. Dev Biol. 2013 Mar 15;375(2):172-81 |
1* | J:45117 Southard-Smith EM, Kos L, Pavan WJ, Sox10 mutation disrupts neural crest development in Dom Hirschsprung mouse model. Nat Genet. 1998 Jan;18(1):60-4 |
1 | J:98431 Stolt CC, Lommes P, Friedrich RP, Wegner M, Transcription factors Sox8 and Sox10 perform non-equivalent roles during oligodendrocyte development despite functional redundancy. Development. 2004 May;131(10):2349-58 |
1 | J:84301 Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M, The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 2003 Jul 1;17(13):1677-89 |
1 | J:116148 Stolt CC, Schlierf A, Lommes P, Hillgartner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M, SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell. 2006 Nov;11(5):697-709 |
1* | J:98585 Stolt CC, Schmitt S, Lommes P, Sock E, Wegner M, Impact of transcription factor Sox8 on oligodendrocyte specification in the mouse embryonic spinal cord. Dev Biol. 2005 May 15;281(2):309-17 |
1* | J:314172 Sundaram VK, El Jalkh T, Barakat R, Fernandez CJI, Massaad C, Grenier J, Retracing Schwann Cell Developmental Transitions in Embryonic Dissociated DRG/Schwann Cell Cocultures in Mice. Front Cell Neurosci. 2021;15:590537 |
1 | J:105340 Tan M, Hu X, Qi Y, Park J, Cai J, Qiu M, Gli3 mutation rescues the generation, but not the differentiation, of oligodendrocytes in Shh mutants. Brain Res. 2006 Jan 5;1067(1):158-63 |
1 | J:202753 Uesaka T, Nagashimada M, Enomoto H, GDNF signaling levels control migration and neuronal differentiation of enteric ganglion precursors. J Neurosci. 2013 Oct 9;33(41):16372-82 |
2* | J:200791 Wakaoka T, Motohashi T, Hayashi H, Kuze B, Aoki M, Mizuta K, Kunisada T, Ito Y, Tracing Sox10-expressing cells elucidates the dynamic development of the mouse inner ear. Hear Res. 2013 Aug;302:17-25 |
1* | J:337458 Waldhauser V, Baroti T, Frob F, Wegner M, PBAF Subunit Pbrm1 Selectively Influences the Transition from Progenitors to Pre-Myelinating Cells during Oligodendrocyte Development. Cells. 2023 Jun 6;12(12) |
1* | J:66518 Watanabe K, Takeda K, Katori Y, Ikeda K, Oshima T, Yasumoto K, Saito H, Takasaka T, Shibahara S, Expression of the Sox10 gene during mouse inner ear development. Brain Res Mol Brain Res. 2000 Dec 8;84(1-2):141-5 |
1* | J:288669 Wedel M, Frob F, Elsesser O, Wittmann MT, Lie DC, Reis A, Wegner M, Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation. Nucleic Acids Res. 2020 May 21;48(9):4839-4857 |
1* | J:172177 Werner T, Hammer A, Wahlbuhl M, Bosl MR, Wegner M, Multiple conserved regulatory elements with overlapping functions determine Sox10 expression in mouse embryogenesis. Nucleic Acids Res. 2007;35(19):6526-38 |
1 | J:343328 Xie Z, Ma XH, Bai QF, Tang J, Sun JH, Jiang F, Guo W, Wang CM, Yang R, Wen YC, Wang FY, Chen YX, Zhang H, He DZ, Kelley MW, Yang S, Zhang WJ, ZBTB20 is essential for cochlear maturation and hearing in mice. Proc Natl Acad Sci U S A. 2023 Jun 13;120(24):e2220867120 |
1 | J:81003 Young HM, Bergner AJ, Muller T, Acquisition of neuronal and glial markers by neural crest-derived cells in the mouse intestine. J Comp Neurol. 2003 Jan 27;456(1):1-11 |
1 | J:347625 Yu Q, Liu L, Du M, Muller D, Gu Y, Gao Z, Xin X, Gu Y, He M, Marquardt T, Wang L, Sacral Neural Crest-Independent Origin of the Enteric Nervous System in Mouse. Gastroenterology. 2024 Mar 5; |
1 | J:208340 Zhu Q, Zhao X, Zheng K, Li H, Huang H, Zhang Z, Mastracci T, Wegner M, Chen Y, Sussel L, Qiu M, Genetic evidence that Nkx2.2 and Pdgfra are major determinants of the timing of oligodendrocyte differentiation in the developing CNS. Development. 2014 Feb;141(3):548-55 |
1 | J:168041 Zhu Y, Park J, Hu X, Zheng K, Li H, Cao Q, Feng GS, Qiu M, Control of oligodendrocyte generation and proliferation by Shp2 protein tyrosine phosphatase. Glia. 2010 Sep;58(12):1407-14 |
Sox11 SRY (sex determining region Y)-box 11 (Synonyms: 1110038H03Rik, 6230403H02Rik, end1) | |
Results | Reference |
1 | J:72872 Bain G, Mansergh FC, Wride MA, Hance JE, Isogawa A, Rancourt SL, Ray WJ, Yoshimura Y, Tsuzuki T, Gottlieb DI, Rancourt DE, ES cell neural differentiation reveals a substantial number of novel ESTs. Funct Integr Genomics. 2000 Sep;1(2):127-139 |
1 | J:225805 Chen C, Lee GA, Pourmorady A, Sock E, Donoghue MJ, Orchestration of Neuronal Differentiation and Progenitor Pool Expansion in the Developing Cortex by SoxC Genes. J Neurosci. 2015 Jul 22;35(29):10629-42 |
1* | J:63842 Cheung M, Abu-Elmagd M, Clevers H, Scotting PJ, Roles of Sox4 in central nervous system development. Brain Res Mol Brain Res. 2000 Jun 23;79(1-2):180-91 |
2 | J:306221 Chiang SY, Wu HC, Lin SY, Chen HY, Wang CF, Yeh NH, Shih JH, Huang YS, Kuo HC, Chou SJ, Chen RH, Usp11 controls cortical neurogenesis and neuronal migration through Sox11 stabilization. Sci Adv. 2021 Feb;7(7) |
1* | J:173070 Dy P, Penzo-Mendez A, Wang H, Pedraza CE, Macklin WB, Lefebvre V, The three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular properties. Nucleic Acids Res. 2008 May;36(9):3101-17 |
1 | J:269420 Franz H, Villarreal A, Heidrich S, Videm P, Kilpert F, Mestres I, Calegari F, Backofen R, Manke T, Vogel T, DOT1L promotes progenitor proliferation and primes neuronal layer identity in the developing cerebral cortex. Nucleic Acids Res. 2019 Jan 10;47(1):168-183 |
1* | J:203540 Gadi J, Jung SH, Lee MJ, Jami A, Ruthala K, Kim KM, Cho NH, Jung HS, Kim CH, Lim SK, The transcription factor protein Sox11 enhances early osteoblast differentiation by facilitating proliferation and the survival of mesenchymal and osteoblast progenitors. J Biol Chem. 2013 Aug 30;288(35):25400-13 |
1 | J:332402 Hockman D, Adameyko I, Kaucka M, Barraud P, Otani T, Hunt A, Hartwig AC, Sock E, Waithe D, Franck MCM, Ernfors P, Ehinger S, Howard MJ, Brown N, Reese J, Baker CVH, Striking parallels between carotid body glomus cell and adrenal chromaffin cell development. Dev Biol. 2018 Dec 1;444 Suppl 1(Suppl 1):S308-S324 |
1 | J:137911 Hoser M, Potzner MR, Koch JM, Bosl MR, Wegner M, Sock E, Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors. Mol Cell Biol. 2008 Aug;28(15):4675-87 |
1* | J:198192 Huang J, Arsenault M, Kann M, Lopez-Mendez C, Saleh M, Wadowska D, Taglienti M, Ho J, Miao Y, Sims D, Spears J, Lopez A, Wright G, Hartwig S, The transcription factor Sry-related HMG box-4 (SOX4) is required for normal renal development in vivo. Dev Dyn. 2013 Jun;242(6):790-9 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:199663 Jiang Y, Ding Q, Xie X, Libby RT, Lefebvre V, Gan L, Transcription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells. J Biol Chem. 2013 Jun 21;288(25):18429-38 |
1* | J:48317 Kuhlbrodt K, Herbarth B, Sock E, Enderich J, Hermans-Borgmeyer I, Wegner M, Cooperative function of POU proteins and SOX proteins in glial cells. J Biol Chem. 1998 Jun 26;273(26):16050-7 |
2 | J:325428 Liu J, Yang M, Su M, Liu B, Zhou K, Sun C, Ba R, Yu B, Zhang B, Zhang Z, Fan W, Wang K, Zhong M, Han J, Zhao C, FOXG1 sequentially orchestrates subtype specification of postmitotic cortical projection neurons. Sci Adv. 2022 May 27;8(21):eabh3568 |
1 | J:340389 Luo Z, Xia M, Shi W, Zhao C, Wang J, Xin D, Dong X, Xiong Y, Zhang F, Berry K, Ogurek S, Liu X, Rao R, Xing R, Wu LMN, Cui S, Xu L, Lin Y, Ma W, Tian S, Xie Q, Zhang L, Xin M, Wang X, Yue F, Zheng H, Liu Y, Stevenson CB, de Blank P, Perentesis JP, Gilbertson RJ, Li H, Ma J, Zhou W, Taylor MD, Lu QR, Human fetal cerebellar cell atlas informs medulloblastoma origin and oncogenesis. Nature. 2022 Dec;612(7941):787-794 |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:279389 Miao Q, Hill MC, Chen F, Mo Q, Ku AT, Ramos C, Sock E, Lefebvre V, Nguyen H, SOX11 and SOX4 drive the reactivation of an embryonic gene program during murine wound repair. Nat Commun. 2019 Sep 6;10(1):4042 |
1 | J:309384 Neirijnck Y, Reginensi A, Renkema KY, Massa F, Kozlov VM, Dhib H, Bongers EMHF, Feitz WF, van Eerde AM, Lefebvre V, Knoers NVAM, Tabatabaei M, Schulz H, McNeill H, Schaefer F, Wegner M, Sock E, Schedl A, Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT). Kidney Int. 2018 May;93(5):1142-1153 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:104307 Wilson ME, Yang KY, Kalousova A, Lau J, Kosaka Y, Lynn FC, Wang J, Mrejen C, Episkopou V, Clevers HC, German MS, The HMG Box Transcription Factor Sox4 Contributes to the Development of the Endocrine Pancreas. Diabetes. 2005 Dec;54(12):3402-9 |
Sox12 SRY (sex determining region Y)-box 12 (Synonyms: 2010205A02Rik) | |
Results | Reference |
1* | J:173070 Dy P, Penzo-Mendez A, Wang H, Pedraza CE, Macklin WB, Lefebvre V, The three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular properties. Nucleic Acids Res. 2008 May;36(9):3101-17 |
1 | J:137911 Hoser M, Potzner MR, Koch JM, Bosl MR, Wegner M, Sock E, Sox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factors. Mol Cell Biol. 2008 Aug;28(15):4675-87 |
1* | J:198192 Huang J, Arsenault M, Kann M, Lopez-Mendez C, Saleh M, Wadowska D, Taglienti M, Ho J, Miao Y, Sims D, Spears J, Lopez A, Wright G, Hartwig S, The transcription factor Sry-related HMG box-4 (SOX4) is required for normal renal development in vivo. Dev Dyn. 2013 Jun;242(6):790-9 |
1* | J:104307 Wilson ME, Yang KY, Kalousova A, Lau J, Kosaka Y, Lynn FC, Wang J, Mrejen C, Episkopou V, Clevers HC, German MS, The HMG Box Transcription Factor Sox4 Contributes to the Development of the Endocrine Pancreas. Diabetes. 2005 Dec;54(12):3402-9 |
Sox13 SRY (sex determining region Y)-box 13 | |
Results | Reference |
1* | J:139199 Dumitriu B, Patrick MR, Petschek JP, Cherukuri S, Klingmuller U, Fox PL, Lefebvre V, Sox6 cell-autonomously stimulates erythroid cell survival, proliferation, and terminal maturation and is thereby an important enhancer of definitive erythropoiesis during mouse development. Blood. 2006 Aug 15;108(4):1198-207 |
1 | J:45482 Roose J, Korver W, Oving E, Wilson A, Wagenaar G, Markman M, Lamers W, Clevers H, High expression of the HMG box factor sox-13 in arterial walls during embryonic development. Nucleic Acids Res. 1998 Jan 15;26(2):469-76 |
1* | J:104307 Wilson ME, Yang KY, Kalousova A, Lau J, Kosaka Y, Lynn FC, Wang J, Mrejen C, Episkopou V, Clevers HC, German MS, The HMG Box Transcription Factor Sox4 Contributes to the Development of the Endocrine Pancreas. Diabetes. 2005 Dec;54(12):3402-9 |
Sox14 SRY (sex determining region Y)-box 14 | |
Results | Reference |
2 | J:188332 Delogu A, Sellers K, Zagoraiou L, Bocianowska-Zbrog A, Mandal S, Guimera J, Rubenstein JL, Sugden D, Jessell T, Lumsden A, Subcortical visual shell nuclei targeted by ipRGCs develop from a Sox14+-GABAergic progenitor and require Sox14 to regulate daily activity rhythms. Neuron. 2012 Aug 23;75(4):648-62 |
1 | J:244498 Lee B, Lee M, Song S, Loi LD, Lam DT, Yoon J, Baek K, Curtis DJ, Jeong Y, Specification of neurotransmitter identity by Tal1 in thalamic nuclei. Dev Dyn. 2017 Oct;246(10):749-758 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:147427 Vue TY, Bluske K, Alishahi A, Yang LL, Koyano-Nakagawa N, Novitch B, Nakagawa Y, Sonic hedgehog signaling controls thalamic progenitor identity and nuclei specification in mice. J Neurosci. 2009 Apr 8;29(14):4484-97 |
1 | J:312485 Zhang Q, Zhang L, Huang Y, Ma P, Mao B, Ding YQ, Song NN, Satb2 regulates the development of dopaminergic neurons in the arcuate nucleus by Dlx1. Cell Death Dis. 2021 Sep 25;12(10):879 |
Sox17 SRY (sex determining region Y)-box 17 | |
Results | Reference |
1 | J:333725 Chiang IKN, Graus MS, Kirschnick N, Davidson T, Luu W, Harwood R, Jiang K, Li B, Wong YY, Moustaqil M, Lesieur E, Skoczylas R, Kouskoff V, Kazenwadel J, Arriola-Martinez L, Sierecki E, Gambin Y, Alitalo K, Kiefer F, Harvey NL, Francois M, The blood vasculature instructs lymphatic patterning in a SOX7-dependent manner. EMBO J. 2023 Mar 1;42(5):e109032 |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
2 | J:109303 Park KS, Wells JM, Zorn AM, Wert SE, Whitsett JA, Sox17 influences the differentiation of respiratory epithelial cells. Dev Biol. 2006 Jun 1;294(1):192-202 |
1 | J:151981 Spence JR, Lange AW, Lin SC, Kaestner KH, Lowy AM, Kim I, Whitsett JA, Wells JM, Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell. 2009 Jul;17(1):62-74 |
1 | J:332220 Uchida A, Imaimatsu K, Suzuki H, Han X, Ushioda H, Uemura M, Imura-Kishi K, Hiramatsu R, Takase HM, Hirate Y, Ogura A, Kanai-Azuma M, Kudo A, Kanai Y, SOX17-positive rete testis epithelium is required for Sertoli valve formation and normal spermiogenesis in the male mouse. Nat Commun. 2022 Dec 21;13(1):7860 |
1 | J:241851 Villani R, Hodgson S, Legrand J, Greaney J, Wong HY, Pichol-Thievend C, Adolphe C, Wainwight B, Francois M, Khosrotehrani K, Dominant-negative Sox18 function inhibits dermal papilla maturation and differentiation in all murine hair types. Development. 2017 May 15;144(10):1887-1895 |
Sox18 SRY (sex determining region Y)-box 18 (Synonyms: Ragl, Sry-related HMG-box gene 18) | |
Results | Reference |
1 | J:356109 Ge W, Tan SJ, Wang SH, Li L, Sun XF, Shen W, Wang X, Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development. Theranostics. 2020;10(17):7581-7598 |
1 | J:241851 Villani R, Hodgson S, Legrand J, Greaney J, Wong HY, Pichol-Thievend C, Adolphe C, Wainwight B, Francois M, Khosrotehrani K, Dominant-negative Sox18 function inhibits dermal papilla maturation and differentiation in all murine hair types. Development. 2017 May 15;144(10):1887-1895 |
Sox21 SRY (sex determining region Y)-box 21 (Synonyms: Sox25) | |
Results | Reference |
1 | J:336102 Eenjes E, Benthem F, Boerema-de Munck A, Buscop-van Kempen M, Tibboel D, Rottier RJ, Distinct roles for SOX2 and SOX21 in differentiation, distribution and maturation of pulmonary neuroendocrine cells. Cell Mol Life Sci. 2023 Mar 3;80(3):79 |
Sp1 trans-acting transcription factor 1 (Synonyms: 1110003E12Rik, Sp1-1) | |
Results | Reference |
3* | J:306453 Kajioka D, Suzuki K, Matsushita S, Hino S, Sato T, Takada S, Isono K, Takeo T, Kajimoto M, Nakagata N, Nakao M, Suyama M, DeFalco T, Miyagawa S, Yamada G, Sexual fate of murine external genitalia development: Conserved transcriptional competency for male-biased genes in both sexes. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2024067118 |
1 | J:123073 Kruger I, Vollmer M, Simmons DG, Elsasser HP, Philipsen S, Suske G, Sp1/Sp3 compound heterozygous mice are not viable: Impaired erythropoiesis and severe placental defects. Dev Dyn. 2007 Aug;236(8):2235-44 |
1* | J:40975 Sack MN, Disch DL, Rockman HA, Kelly DP, A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6438-43 |
Sp2 Sp2 transcription factor | |
Results | Reference |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
Sp3 trans-acting transcription factor 3 (Synonyms: D130027J01Rik) | |
Results | Reference |
1* | J:146765 Golonzhka O, Metzger D, Bornert JM, Bay BK, Gross MK, Kioussi C, Leid M, Ctip2/Bcl11b controls ameloblast formation during mammalian odontogenesis. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4278-83 |
1 | J:123073 Kruger I, Vollmer M, Simmons DG, Elsasser HP, Philipsen S, Suske G, Sp1/Sp3 compound heterozygous mice are not viable: Impaired erythropoiesis and severe placental defects. Dev Dyn. 2007 Aug;236(8):2235-44 |
1* | J:40975 Sack MN, Disch DL, Rockman HA, Kelly DP, A role for Sp and nuclear receptor transcription factors in a cardiac hypertrophic growth program. Proc Natl Acad Sci U S A. 1997 Jun 10;94(12):6438-43 |
Sp6 trans-acting transcription factor 6 (Synonyms: 1110025J03Rik, Epfn, epiprofin, Klf14) | |
Results | Reference |
1* | J:146765 Golonzhka O, Metzger D, Bornert JM, Bay BK, Gross MK, Kioussi C, Leid M, Ctip2/Bcl11b controls ameloblast formation during mammalian odontogenesis. Proc Natl Acad Sci U S A. 2009 Mar 17;106(11):4278-83 |
1 | J:118173 Jarvinen E, Salazar-Ciudad I, Birchmeier W, Taketo MM, Jernvall J, Thesleff I, Continuous tooth generation in mouse is induced by activated epithelial Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18627-32 |
1* | J:132157 Nakamura T, de Vega S, Fukumoto S, Jimenez L, Unda F, Yamada Y, Transcription factor epiprofin is essential for tooth morphogenesis by regulating epithelial cell fate and tooth number. J Biol Chem. 2008 Feb 22;283(8):4825-33 |
1 | J:309402 Nakamura T, Jimenez-Rojo L, Koyama E, Pacifici M, de Vega S, Iwamoto M, Fukumoto S, Unda F, Yamada Y, Epiprofin Regulates Enamel Formation and Tooth Morphogenesis by Controlling Epithelial-Mesenchymal Interactions During Tooth Development. J Bone Miner Res. 2017 Mar;32(3):601-610 |
1 | J:354246 Zhu S, Huo S, Wang Z, Huang C, Li C, Song H, Yang X, He R, Ding C, Qiu M, Zhu XJ, Follistatin controls the number of murine teeth by limiting TGF-beta signaling. iScience. 2024 Sep 20;27(9):110785 |
Sp7 Sp7 transcription factor 7 (Synonyms: 6430578P22Rik, osterix, Osx) | |
Results | Reference |
1 | J:124269 Abzhanov A, Rodda SJ, McMahon AP, Tabin CJ, Regulation of skeletogenic differentiation in cranial dermal bone. Development. 2007 Sep;134(17):3133-44 |
2 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
1 | J:337598 Au TYK, Yip RKH, Wynn SL, Tan TY, Fu A, Geng YH, Szeto IYY, Niu B, Yip KY, Cheung MCH, Lovell-Badge R, Cheah KSE, Hypomorphic and dominant-negative impact of truncated SOX9 dysregulates Hedgehog-Wnt signaling, causing campomelia. Proc Natl Acad Sci U S A. 2023 Jan 3;120(1):e2208623119 |
1 | J:170583 Baek JA, Lan Y, Liu H, Maltby KM, Mishina Y, Jiang R, Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation. Dev Biol. 2011 Feb 15;350(2):520-31 |
1 | J:237340 Ben Shoham A, Rot C, Stern T, Krief S, Akiva A, Dadosh T, Sabany H, Lu Y, Kadler KE, Zelzer E, Deposition of collagen type I onto skeletal endothelium reveals a new role for blood vessels in regulating bone morphology. Development. 2016 Nov 01;143(21):3933-3943 |
1 | J:208766 Chen J, Tu X, Esen E, Joeng KS, Lin C, Arbeit JM, Ruegg MA, Hall MN, Ma L, Long F, WNT7B promotes bone formation in part through mTORC1. PLoS Genet. 2014 Jan;10(1):e1004145 |
1 | J:274818 Chen Y, Wang Z, Chen Y, Zhang Y, Conditional deletion of Bmp2 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Cell Tissue Res. 2019 May;376(2):199-210 |
1 | J:217906 Cooley MA, Harikrishnan K, Oppel JA, Miler SF, Barth JL, Haycraft CJ, Reddy SV, Scott Argraves W, Fibulin-1 is required for bone formation and Bmp-2-mediated induction of Osterix. Bone. 2014 Dec;69:30-8 |
1 | J:293199 Crespo-Enriquez I, Hodgson T, Zakaria S, Cadoni E, Shah M, Allen S, Al-Khishali A, Mao Y, Yiu A, Petzold J, Villagomez-Olea G, Pitsillides AA, Irvine KD, Francis-West P, Dchs1-Fat4 regulation of osteogenic differentiation in mouse. Development. 2019 Jul 29;146(14):dev176776 |
1 | J:104802 Deckelbaum RA, Majithia A, Booker T, Henderson JE, Loomis CA, The homeoprotein engrailed 1 has pleiotropic functions in calvarial intramembranous bone formation and remodeling. Development. 2006 Jan;133(1):63-74 |
1 | J:237001 Duan X, Bradbury SR, Olsen BR, Berendsen AD, VEGF stimulates intramembranous bone formation during craniofacial skeletal development. Matrix Biol. 2016 May-Jul;52-54:127-40 |
1* | J:195901 Ehlen H, Inactivation of anoctamin-6/Tmem16f, a regulator of phosphatidylserine scrambling in osteoblasts, leads to decreased mineral deposition in skeletal tissues. J Bone Miner Res. 2013;28(2):246-59 |
1 | J:127545 Engleka KA, Wu M, Zhang M, Antonucci NB, Epstein JA, Menin is required in cranial neural crest for palatogenesis and perinatal viability. Dev Biol. 2007 Nov 15;311(2):524-37 |
1 | J:294823 Fabik J, Kovacova K, Kozmik Z, Machon O, Neural crest cells require Meis2 for patterning the mandibular arch via the Sonic hedgehog pathway. Biol Open. 2020 Jul 2;9(6):bio052043 |
1 | J:330128 Fabik J, Psutkova V, Machon O, Meis2 controls skeletal formation in the hyoid region. Front Cell Dev Biol. 2022;10:951063 |
1 | J:308983 Farmer DT, Mlcochova H, Zhou Y, Koelling N, Wang G, Ashley N, Bugacov H, Chen HJ, Parvez R, Tseng KC, Merrill AE, Maxson RE Jr, Wilkie AOM, Crump JG, Twigg SRF, The developing mouse coronal suture at single-cell resolution. Nat Commun. 2021 Aug 10;12(1):4797 |
1* | J:203540 Gadi J, Jung SH, Lee MJ, Jami A, Ruthala K, Kim KM, Cho NH, Jung HS, Kim CH, Lim SK, The transcription factor protein Sox11 enhances early osteoblast differentiation by facilitating proliferation and the survival of mesenchymal and osteoblast progenitors. J Biol Chem. 2013 Aug 30;288(35):25400-13 |
1 | J:185118 Galli GG, Honnens de Lichtenberg K, Carrara M, Hans W, Wuelling M, Mentz B, Multhaupt HA, Fog CK, Jensen KT, Rappsilber J, Vortkamp A, Coulton L, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Calogero RA, Couchman JR, Lund AH, Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone. PLoS Genet. 2012 May;8(5):e1002711 |
1 | J:150187 Guo X, Mak KK, Taketo MM, Yang Y, The Wnt/beta-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturation. PLoS One. 2009;4(6):e6067 |
1 | J:236411 He X, Ohba S, Hojo H, McMahon AP, AP-1 family members act with Sox9 to promote chondrocyte hypertrophy. Development. 2016 Aug 15;143(16):3012-23 |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1 | J:98426 Hill TP, Spater D, Taketo MM, Birchmeier W, Hartmann C, Canonical Wnt/beta-Catenin Signaling Prevents Osteoblasts from Differentiating into Chondrocytes. Dev Cell. 2005 May;8(5):727-38 |
1 | J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132 |
1 | J:256071 Iyyanar PPR, Nazarali AJ, Hoxa2 Inhibits Bone Morphogenetic Protein Signaling during Osteogenic Differentiation of the Palatal Mesenchyme. Front Physiol. 2017;8:929 |
1 | J:178499 Joeng KS, Schumacher CA, Zylstra-Diegel CR, Long F, Williams BO, Lrp5 and Lrp6 redundantly control skeletal development in the mouse embryo. Dev Biol. 2011 Nov 15;359(2):222-9 |
2 | J:129783 Kaback LA, Soung do Y, Naik A, Smith N, Schwarz EM, O'Keefe RJ, Drissi H, Osterix/Sp7 regulates mesenchymal stem cell mediated endochondral ossification. J Cell Physiol. 2008 Jan;214(1):173-82 |
1 | J:143588 Kamiya N, Ye L, Kobayashi T, Mochida Y, Yamauchi M, Kronenberg HM, Feng JQ, Mishina Y, BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development. 2008 Nov;135(22):3801-11 |
1 | J:268341 Lee SY, Abel ED, Long F, Glucose metabolism induced by Bmp signaling is essential for murine skeletal development. Nat Commun. 2018 Nov 16;9(1):4831 |
1* | J:355649 Li Q, Jiang S, Lei K, Han H, Chen Y, Lin W, Xiong Q, Qi X, Gan X, Sheng R, Wang Y, Zhang Y, Ma J, Li T, Lin S, Zhou C, Chen D, Yuan Q, Metabolic rewiring during bone development underlies tRNA m7G-associated primordial dwarfism. J Clin Invest. 2024 Sep 10;134(20) |
1 | J:319475 Liao C, Lu M, Hong Y, Mao C, Chen J, Ren C, Lin M, Chen W, Osteogenic and angiogenic profiles of the palatal process of the maxilla and the palatal process of the palatine bone. J Anat. 2022 Feb;240(2):385-397 |
2 | J:333798 Luo S, Liu Z, Bian Q, Wang X, Ectomesenchymal Six1 controls mandibular skeleton formation. Front Genet. 2023;14:1082911 |
1 | J:347800 Lv Y, Wang Q, Lin C, Zheng X, Zhang Y, Hu X, Overexpression of Fgf18 in cranial neural crest cells recapitulates Pierre Robin sequence in mice. Front Cell Dev Biol. 2024;12:1376814 |
1* | J:270314 Mitomo K, Matsunaga S, Kitamura K, Nakamura T, Saito A, Komori T, Muramatsu T, Yamaguchi A, Sphenoid bone hypoplasia is a skeletal phenotype of cleidocranial dysplasia in a mouse model and patients. Bone. 2019 Mar;120:176-186 |
1* | J:265083 Mullen RD, Wang Y, Liu B, Moore EL, Behringer RR, Osterix functions downstream of anti-Mullerian hormone signaling to regulate Mullerian duct regression. Proc Natl Acad Sci U S A. 2018 Aug 14;115(33):8382-8387 |
1 | J:232190 Noda K, Kitami M, Kitami K, Kaku M, Komatsu Y, Canonical and noncanonical intraflagellar transport regulates craniofacial skeletal development. Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2589-97 |
2 | J:181485 Oh JH, Park SY, de Crombrugghe B, Kim JE, Chondrocyte-specific ablation of Osterix leads to impaired endochondral ossification. Biochem Biophys Res Commun. 2012 Feb 24;418(4):634-40 |
1 | J:92630 Ohyama Y, Nifuji A, Maeda Y, Amagasa T, Noda M, Spaciotemporal association and bone morphogenetic protein regulation of sclerostin and osterix expression during embryonic osteogenesis. Endocrinology. 2004 Oct;145(10):4685-92 |
2 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1 | J:299239 Qin X, Jiang Q, Nagano K, Moriishi T, Miyazaki T, Komori H, Ito K, Mark KV, Sakane C, Kaneko H, Komori T, Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts. PLoS Genet. 2020 Nov;16(11):e1009169 |
1 | J:333326 Suh J, Kim NK, Shim W, Lee SH, Kim HJ, Moon E, Sesaki H, Jang JH, Kim JE, Lee YS, Mitochondrial fragmentation and donut formation enhance mitochondrial secretion to promote osteogenesis. Cell Metab. 2023 Feb 7;35(2):345-360.e7 |
1* | J:285711 Sweat YY, Sweat M, Mansaray M, Cao H, Eliason S, Adeyemo WL, Gowans LJJ, Eshete MA, Anand D, Chalkley C, Saadi I, Lachke SA, Butali A, Amendt BA, Six2 regulates Pax9 expression, palatogenesis and craniofacial bone formation. Dev Biol. 2020 Feb 15;458(2):246-256 |
1 | J:125052 Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H, Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification. Mol Cell Biol. 2007 Aug;27(16):5650-63 |
1* | J:269344 Teng CS, Ting MC, Farmer DT, Brockop M, Maxson RE, Crump JG, Altered bone growth dynamics prefigure craniosynostosis in a zebrafish model of Saethre-Chotzen syndrome. Elife. 2018 Oct 25;7:e37024 |
1 | J:286823 Wang L, Tang Q, Xu J, Li H, Yang T, Li L, Machon O, Hu T, Chen Y, The transcriptional regulator MEIS2 sets up the ground state for palatal osteogenesis in mice. J Biol Chem. 2020 Apr 17;295(16):5449-5460 |
1 | J:236410 Watson EC, Koenig MN, Grant ZL, Whitehead L, Trounson E, Dewson G, Coultas L, Apoptosis regulates endothelial cell number and capillary vessel diameter but not vessel regression during retinal angiogenesis. Development. 2016 Aug 15;143(16):2973-82 |
1 | J:185130 Wei J, Shi Y, Zheng L, Zhou B, Inose H, Wang J, Guo XE, Grosschedl R, Karsenty G, miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. J Cell Biol. 2012 May 14;197(4):509-21 |
1 | J:283053 Xu J, Wang L, Li H, Yang T, Zhang Y, Hu T, Huang Z, Chen Y, Shox2 regulates osteogenic differentiation and pattern formation during hard palate development in mice. J Biol Chem. 2019 Nov 29;294(48):18294-18305 |
1* | J:307192 Yadav PS, Feng S, Cong Q, Kim H, Liu Y, Yang Y, Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118 |
1 | J:326460 Yang R, Li R, Huang Z, Zuo Y, Yue H, Wu H, Gu F, Wang F, He M, Bian Z, Mycn deficiency underlies the development of orofacial clefts in mice and humans. Hum Mol Genet. 2022 Mar 3;31(5):803-815 |
1 | J:218833 Zhao H, Zhou W, Yao Z, Wan Y, Cao J, Zhang L, Zhao J, Li H, Zhou R, Li B, Wei G, Zhang Z, French CA, Dekker JD, Yang Y, Fisher SE, Tucker HO, Guo X, Foxp1/2/4 regulate endochondral ossification as a suppresser complex. Dev Biol. 2015 Feb 15;398(2):242-54 |
1 | J:292430 Zhou T, Gao B, Fan Y, Liu Y, Feng S, Cong Q, Zhang X, Zhou Y, Yadav PS, Lin J, Wu N, Zhao L, Huang D, Zhou S, Su P, Yang Y, Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ss-catenin. Elife. 2020 Mar 18;9:e52779 |
Sp8 trans-acting transcription factor 8 (Synonyms: D930049B17Rik, mBtd) | |
Results | Reference |
1* | J:86196 Bell SM, Schreiner CM, Waclaw RR, Campbell K, Potter SS, Scott WJ, Sp8 is crucial for limb outgrowth and neuropore closure. Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12195-200 |
1* | J:193583 Cai Y, Zhang Q, Wang C, Zhang Y, Ma T, Zhou X, Tian M, Rubenstein JL, Yang Z, Nuclear receptor COUP-TFII-expressing neocortical interneurons are derived from the medial and lateral/caudal ganglionic eminence and define specific subsets of mature interneurons. J Comp Neurol. 2013 Feb 1;521(2):479-97 |
1 | J:268552 Denaxa M, Neves G, Rabinowitz A, Kemlo S, Liodis P, Burrone J, Pachnis V, Modulation of Apoptosis Controls Inhibitory Interneuron Number in the Cortex. Cell Rep. 2018 Feb 13;22(7):1710-1721 |
1 | J:309450 Doeppner TR, Herz J, Bahr M, Tonchev AB, Stoykova A, Zbtb20 Regulates Developmental Neurogenesis in the Olfactory Bulb and Gliogenesis After Adult Brain Injury. Mol Neurobiol. 2019 Jan;56(1):567-582 |
2 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1* | J:252114 Kohli V, Nardini D, Ehrman LA, Waclaw RR, Characterization of Glcci1 expression in a subpopulation of lateral ganglionic eminence progenitors in the mouse telencephalon. Dev Dyn. 2018 Jan;247(1):222-228 |
1 | J:348287 Liang XG, Hoang K, Meyerink BL, Kc P, Paraiso K, Wang L, Jones IR, Zhang Y, Katzman S, Finn TS, Tsyporin J, Qu F, Chen Z, Visel A, Kriegstein A, Shen Y, Pilaz LJ, Chen B, A conserved molecular logic for neurogenesis to gliogenesis switch in the cerebral cortex. Proc Natl Acad Sci U S A. 2024 May 14;121(20):e2321711121 |
1 | J:226398 Miyoshi G, Young A, Petros T, Karayannis T, McKenzie Chang M, Lavado A, Iwano T, Nakajima M, Taniguchi H, Huang ZJ, Heintz N, Oliver G, Matsuzaki F, Machold RP, Fishell G, Prox1 Regulates the Subtype-Specific Development of Caudal Ganglionic Eminence-Derived GABAergic Cortical Interneurons. J Neurosci. 2015 Sep 16;35(37):12869-89 |
1* | J:262512 Raju CS, Spatazza J, Stanco A, Larimer P, Sorrells SF, Kelley KW, Nicholas CR, Paredes MF, Lui JH, Hasenstaub AR, Kriegstein AR, Alvarez-Buylla A, Rubenstein JL, Oldham MC, Secretagogin is Expressed by Developing Neocortical GABAergic Neurons in Humans but not Mice and Increases Neurite Arbor Size and Complexity. Cereb Cortex. 2018 Jun 1;28(6):1946-1958 |
1 | J:328873 Shang Z, Yang L, Wang Z, Tian Y, Gao Y, Su Z, Guo R, Li W, Liu G, Li X, Yang Z, Li Z, Zhang Z, The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity. Front Cell Dev Biol. 2022;10:948331 |
1 | J:350099 Song X, Chen H, Shang Z, Du H, Li Z, Wen Y, Liu G, Qi D, You Y, Yang Z, Zhang Z, Xu Z, Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons. Neurosci Bull. 2021 Jul;37(7):985-998 |
2 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1 | J:107576 Waclaw RR, Allen ZJ 2nd, Bell SM, Erdelyi F, Szabo G, Potter SS, Campbell K, The zinc finger transcription factor Sp8 regulates the generation and diversity of olfactory bulb interneurons. Neuron. 2006 Feb 16;49(4):503-16 |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
1 | J:264125 Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z, SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. Development. 2018 Jul 23;145(14):dev165456 |
Sp9 trans-acting transcription factor 9 | |
Results | Reference |
2 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:361228 Li Z, Shang Z, Sun M, Jiang X, Tian Y, Yang L, Wang Z, Su Z, Liu G, Li X, You Y, Yang Z, Xu Z, Zhang Z, Transcription factor Sp9 is a negative regulator of D1-type MSN development. Cell Death Discov. 2022 Jun 30;8(1):301 |
1 | J:328873 Shang Z, Yang L, Wang Z, Tian Y, Gao Y, Su Z, Guo R, Li W, Liu G, Li X, Yang Z, Li Z, Zhang Z, The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity. Front Cell Dev Biol. 2022;10:948331 |
1 | J:350099 Song X, Chen H, Shang Z, Du H, Li Z, Wen Y, Liu G, Qi D, You Y, Yang Z, Zhang Z, Xu Z, Homeobox Gene Six3 is Required for the Differentiation of D2-Type Medium Spiny Neurons. Neurosci Bull. 2021 Jul;37(7):985-998 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
2 | J:264125 Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z, SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. Development. 2018 Jul 23;145(14):dev165456 |
2 | J:238868 Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z, The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 2016 Aug 02;16(5):1431-44 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
Spaca9 sperm acrosome associated 9 (Synonyms: 1700026L06Rik, Mast) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Spag1 sperm associated antigen 1 (Synonyms: tpis, TPR-containing protein involved in spermatogenesis) | |
Results | Reference |
1* | J:58009 Takaishi M, Huh Nh, A tetratricopeptide repeat-containing protein gene, tpis, whose expression is induced with differentiation of spermatogenic cells. Biochem Biophys Res Commun. 1999 Oct 14;264(1):81-5 |
Spag5 sperm associated antigen 5 (Synonyms: Astrin, D11Bhm180e, Deepest, MAP126, Mastrin, s17, S17) | |
Results | Reference |
1* | J:196507 Kersten FF, van Wijk E, Hetterschijt L, Baubeta K, Peters TA, Aslanyan MG, van der Zwaag B, Wolfrum U, Keunen JE, Roepman R, Kremer H, The mitotic spindle protein SPAG5/Astrin connects to the Usher protein network postmitotically. Cilia. 2012;1(1):2 |
Spag6l sperm associated antigen 6-like (Synonyms: PF16, Spag6) | |
Results | Reference |
1 | J:306188 Yan R, Hu X, Zhang Q, Song L, Zhang M, Zhang Y, Zhao S, Spag6 Negatively Regulates Neuronal Migration During Mouse Brain Development. J Mol Neurosci. 2015 Dec;57(4):463-9 |
Spag17 sperm associated antigen 17 (Synonyms: 4931427F14Rik, PF6) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Sparc secreted acidic cysteine rich glycoprotein (Synonyms: BM-40, osteonectin) | |
Results | Reference |
1* | J:111223 Kitano Y, Kurihara H, Kurihara Y, Maemura K, Ryo Y, Yazaki Y, Harii K, Gene expression of bone matrix proteins and endothelin receptors in endothelin-1-deficient mice revealed by in situ hybridization. J Bone Miner Res. 1998 Feb;13(2):237-44 |
2* | J:321931 Liu J, Wu X, Lu Q, Molecular divergence of mammalian astrocyte progenitor cells at early gliogenesis. Development. 2022 Mar 1;149(5):dev199985 |
1 | J:8425 Mason IJ, Murphy D, Munke M, Francke U, Elliott RW, Hogan BL, Developmental and transformation-sensitive expression of the Sparc gene on mouse chromosome 11. EMBO J. 1986 Aug;5(8):1831-7 |
1 | J:274409 Masuda T, Sankowski R, Staszewski O, Bottcher C, Amann L, Sagar, Scheiwe C, Nessler S, Kunz P, van Loo G, Coenen VA, Reinacher PC, Michel A, Sure U, Gold R, Grun D, Priller J, Stadelmann C, Prinz M, Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution. Nature. 2019 Feb;566(7744):388-392 |
1* | J:74179 Nikaido T, Yokoya S, Mori T, Hagino S, Iseki K, Zhang Y, Takeuchi M, Takaki H, Kikuchi S, Wanaka A, Expression of the novel transcription factor OASIS, which belongs to the CREB/ATF family, in mouse embryo with special reference to bone development. Histochem Cell Biol. 2001 Aug;116(2):141-8 |
1* | J:9026 Nomura S, Wills AJ, Edwards DR, Heath JK, Hogan BL, Developmental expression of 2ar (osteopontin) and SPARC (osteonectin) RNA as revealed by in situ hybridization. J Cell Biol. 1988 Feb;106(2):441-50 |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
1* | J:306243 Shur I, Socher R, Benayahu D, In vivo association of CReMM/CHD9 with promoters in osteogenic cells. J Cell Physiol. 2006 May;207(2):374-8 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1 | J:101174 Wang Y, Xiao R, Yang F, Karim BO, Iacovelli AJ, Cai J, Lerner CP, Richtsmeier JT, Leszl JM, Hill CA, Yu K, Ornitz DM, Elisseeff J, Huso DL, Jabs EW, Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse. Development. 2005 Aug;132(15):3537-48 |
Sparcl1 SPARC-like 1 (Synonyms: Ecm2, hevin, mast9, Sc1) | |
Results | Reference |
1 | J:87426 Gongidi V, Ring C, Moody M, Brekken R, Sage EH, Rakic P, Anton ES, SPARC-like 1 Regulates the Terminal Phase of Radial Glia-Guided Migration in the Cerebral Cortex. Neuron. 2004 Jan 8;41(1):57-69 |
1* | J:190034 Hurley PJ, Marchionni L, Simons BW, Ross AE, Peskoe SB, Miller RM, Erho N, Vergara IA, Ghadessi M, Huang Z, Gurel B, Park BH, Davicioni E, Jenkins RB, Platz EA, Berman DM, Schaeffer EM, Secreted protein, acidic and rich in cysteine-like 1 (SPARCL1) is down regulated in aggressive prostate cancers and is prognostic for poor clinical outcome. Proc Natl Acad Sci U S A. 2012 Sep 11;109(37):14977-82 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
2* | J:321931 Liu J, Wu X, Lu Q, Molecular divergence of mammalian astrocyte progenitor cells at early gliogenesis. Development. 2022 Mar 1;149(5):dev199985 |
Spast spastin (Synonyms: mKIAA1083, Spg4) | |
Results | Reference |
1 | J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6 |
Spata7 spermatogenesis associated 7 (Synonyms: B230306G18Rik, HSD3) | |
Results | Reference |
1* | J:150892 Wang H, den Hollander AI, Moayedi Y, Abulimiti A, Li Y, Collin RW, Hoyng CB, Lopez I, Bray M, Lewis RA, Lupski JR, Mardon G, Koenekoop RK, Chen R, Mutations in SPATA7 cause Leber congenital amaurosis and juvenile retinitis pigmentosa. Am J Hum Genet. 2009 Mar;84(3):380-7 |
Spata13 spermatogenesis associated 13 (Synonyms: ESTM11, mKIAA1112) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Spc24 SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae) (Synonyms: 2410030K01Rik, Spbc24) | |
Results | Reference |
2* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
Spc25 SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae) (Synonyms: 2600017H08Rik, 2610205L13Rik, Spbc25) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Spdef SAM pointed domain containing ets transcription factor (Synonyms: PDEF, Pse) | |
Results | Reference |
1 | J:181435 Gupta D, Harvey SA, Kaminski N, Swamynathan SK, Mouse conjunctival forniceal gene expression during postnatal development and its regulation by Kruppel-like factor 4. Invest Ophthalmol Vis Sci. 2011 Jul;52(8):4951-62 |
1 | J:102106 Shroyer NF, Wallis D, Venken KJ, Bellen HJ, Zoghbi HY, Gfi1 functions downstream of Math1 to control intestinal secretory cell subtype allocation and differentiation. Genes Dev. 2005 Oct 15;19(20):2412-7 |
1 | J:161774 Wang S, Turner EE, Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity. J Neurosci. 2010 Jul 7;30(27):9224-7 |
Speg SPEG complex locus (Synonyms: Apeg1, BPEG, D1Bwg1450e, mKIAA1297, SPEG, SPEGalpha, SPEGbeta) | |
Results | Reference |
1* | J:163968 Liu X, Ramjiganesh T, Chen YH, Chung SW, Hall SR, Schissel SL, Padera RF Jr, Liao R, Ackerman KG, Kajstura J, Leri A, Anversa P, Yet SF, Layne MD, Perrella MA, Disruption of striated preferentially expressed gene locus leads to dilated cardiomyopathy in mice. Circulation. 2009 Jan 20;119(2):261-8 |
Sphk1 sphingosine kinase 1 (Synonyms: 1110006G24Rik, SK1) | |
Results | Reference |
1 | J:243381 Serafimidis I, Rodriguez-Aznar E, Lesche M, Yoshioka K, Takuwa Y, Dahl A, Pan D, Gavalas A, Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. PLoS Biol. 2017 Mar;15(3):e2000949 |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Sphk2 sphingosine kinase 2 | |
Results | Reference |
1 | J:243381 Serafimidis I, Rodriguez-Aznar E, Lesche M, Yoshioka K, Takuwa Y, Dahl A, Pan D, Gavalas A, Pancreas lineage allocation and specification are regulated by sphingosine-1-phosphate signalling. PLoS Biol. 2017 Mar;15(3):e2000949 |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Spi1 Spi-1 proto-oncogene (Synonyms: Dis-1, PU.1, Sfpi-1, Sfpi1, Spi-1, spleen focus forming virus (SFFV) proviral integration oncogene, Tcfpu1, Tfpu.1) | |
Results | Reference |
1 | J:336863 Barry-Carroll L, Greulich P, Marshall AR, Riecken K, Fehse B, Askew KE, Li K, Garaschuk O, Menassa DA, Gomez-Nicola D, Microglia colonize the developing brain by clonal expansion of highly proliferative progenitors, following allometric scaling. Cell Rep. 2023 May 30;42(5):112425 |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
Spib Spi-B transcription factor (Spi-1/PU.1 related) (Synonyms: Spi-B) | |
Results | Reference |
1 | J:188796 de Lau W, Kujala P, Schneeberger K, Middendorp S, Li VS, Barker N, Martens A, Hofhuis F, DeKoter RP, Peters PJ, Nieuwenhuis E, Clevers H, Peyer's patch M cells derived from Lgr5(+) stem cells require SpiB and are induced by RankL in cultured "miniguts". Mol Cell Biol. 2012 Sep;32(18):3639-47 |
Spin1 spindlin 1 (Synonyms: Spin) | |
Results | Reference |
1* | J:355681 Dias Mirandela M, Zoch A, Leismann J, Webb S, Berrens RV, Valsakumar D, Kabayama Y, Auchynnikava T, Schito M, Chowdhury T, MacLeod D, Xiang X, Zou J, Rappsilber J, Allshire RC, Voigt P, Cook AG, Barau J, O'Carroll D, Two-factor authentication underpins the precision of the piRNA pathway. Nature. 2024 Oct;634(8035):979-985 |
Spink5 serine peptidase inhibitor, Kazal type 5 (Synonyms: 2310065D10Rik, LEKT1) | |
Results | Reference |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
1 | J:93050 Yang T, Liang D, Koch PJ, Hohl D, Kheradmand F, Overbeek PA, Epidermal detachment, desmosomal dissociation, and destabilization of corneodesmosin in Spink5-/- mice. Genes Dev. 2004 Oct 1;18(19):2354-8 |
Spint1 serine protease inhibitor, Kunitz type 1 (Synonyms: HAI-1) | |
Results | Reference |
1 | J:99182 Tanaka H, Nagaike K, Takeda N, Itoh H, Kohama K, Fukushima T, Miyata S, Uchiyama S, Uchinokura S, Shimomura T, Miyazawa K, Kitamura N, Yamada G, Kataoka H, Hepatocyte Growth Factor Activator Inhibitor Type 1 (HAI-1) Is Required for Branching Morphogenesis in the Chorioallantoic Placenta. Mol Cell Biol. 2005 Jul;25(13):5687-98 |
Spo11 SPO11 initiator of meiotic double stranded breaks (Synonyms: Spo11a, Spo11b) | |
Results | Reference |
1 | J:316797 Weitzel AJ, Grunwald HA, Weber C, Levina R, Gantz VM, Hedrick SM, Bier E, Cooper KL, Meiotic Cas9 expression mediates gene conversion in the male and female mouse germline. PLoS Biol. 2021 Dec;19(12):e3001478 |
Spocd1 SPOC domain containing 1 (Synonyms: OTTMUSG00000009522) | |
Results | Reference |
2* | J:355681 Dias Mirandela M, Zoch A, Leismann J, Webb S, Berrens RV, Valsakumar D, Kabayama Y, Auchynnikava T, Schito M, Chowdhury T, MacLeod D, Xiang X, Zou J, Rappsilber J, Allshire RC, Voigt P, Cook AG, Barau J, O'Carroll D, Two-factor authentication underpins the precision of the piRNA pathway. Nature. 2024 Oct;634(8035):979-985 |
1 | J:346376 Zoch A, Konieczny G, Auchynnikava T, Stallmeyer B, Rotte N, Heep M, Berrens RV, Schito M, Kabayama Y, Schopp T, Kliesch S, Houston B, Nagirnaja L, O'Bryan MK, Aston KI, Conrad DF, Rappsilber J, Allshire RC, Cook AG, Tuttelmann F, O'Carroll D, C19ORF84 connects piRNA and DNA methylation machineries to defend the mammalian germ line. Mol Cell. 2024 Mar 21;84(6):1021-1035.e11 |
Spock2 sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2 (Synonyms: Gcap26, mKIAA0275, testican-2) | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
Spon1 spondin 1, (f-spondin) extracellular matrix protein (Synonyms: D330035F22Rik, FSP) | |
Results | Reference |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
Spop speckle-type BTB/POZ protein (Synonyms: TEF2) | |
Results | Reference |
1 | J:239074 Cai H, Liu A, Spop promotes skeletal development and homeostasis by positively regulating Ihh signaling. Proc Natl Acad Sci U S A. 2016 Dec 20;113(51):14751-14756 |
Spp1 secreted phosphoprotein 1 (Synonyms: 2ar, 44kDa bone phosphoprotein, Apl-1, BNSP, bone sialoprotein 1, ETA-1, minopontin, OP, Opn, Opnl, osteopontin, osteopontin-like protein, Ric, Spp-1) | |
Results | Reference |
1 | J:124269 Abzhanov A, Rodda SJ, McMahon AP, Tabin CJ, Regulation of skeletogenic differentiation in cranial dermal bone. Development. 2007 Sep;134(17):3133-44 |
1 | J:77612 Akazawa H, Komuro I, Sugitani Y, Yazaki Y, Nagai R, Noda T, Targeted disruption of the homeobox transcription factor Bapx1 results in lethal skeletal dysplasia with asplenia and gastroduodenal malformation. Genes Cells. 2000 Jun;5(6):499-513 |
1 | J:90567 Akiyama H, Lyons JP, Mori-Akiyama Y, Yang X, Zhang R, Zhang Z, Deng JM, Taketo MM, Nakamura T, Behringer RR, McCrea PD, de Crombrugghe B, Interactions between Sox9 and beta-catenin control chondrocyte differentiation. Genes Dev. 2004 May 1;18(9):1072-87 |
2 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
1 | J:91667 Antonopoulou I, Mavrogiannis LA, Wilkie AO, Morriss-Kay GM, Alx4 and Msx2 play phenotypically similar and additive roles in skull vault differentiation. J Anat. 2004 Jun;204(6):487-99 |
1* | J:293506 Cao H, Cao B, Heazlewood CK, Domingues M, Sun X, Debele E, McGregor NE, Sims NA, Heazlewood SY, Nilsson SK, Osteopontin is An Important Regulative Component of the Fetal Bone Marrow Hematopoietic Stem Cell Niche. Cells. 2019 Aug 27;8(9):985 |
1 | J:181527 Chaible LM, Sanches DS, Cogliati B, Mennecier G, Dagli ML, Delayed osteoblastic differentiation and bone development in Cx43 knockout mice. Toxicol Pathol. 2011 Dec;39(7):1046-55 |
1 | J:185530 Chan KM, Wong HL, Jin G, Liu B, Cao R, Cao Y, Lehti K, Tryggvason K, Zhou Z, MT1-MMP Inactivates ADAM9 to Regulate FGFR2 Signaling and Calvarial Osteogenesis. Dev Cell. 2012 Jun 12;22(6):1176-90 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:232617 Chen Z, Yue SX, Zhou G, Greenfield EM, Murakami S, ERK1 and ERK2 regulate chondrocyte terminal differentiation during endochondral bone formation. J Bone Miner Res. 2015 May;30(5):765-74 |
1 | J:97179 Colnot C, de la Fuente L, Huang S, Hu D, Lu C, St-Jacques B, Helms JA, Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development. Development. 2005 Mar;132(5):1057-67 |
1* | J:66902 Colnot C, Sidhu SS, Balmain N, Poirier F, Uncoupling of chondrocyte death and vascular invasion in mouse galectin 3 null mutant bones. Dev Biol. 2001 Jan 1;229(1):203-14 |
1 | J:293199 Crespo-Enriquez I, Hodgson T, Zakaria S, Cadoni E, Shah M, Allen S, Al-Khishali A, Mao Y, Yiu A, Petzold J, Villagomez-Olea G, Pitsillides AA, Irvine KD, Francis-West P, Dchs1-Fat4 regulation of osteogenic differentiation in mouse. Development. 2019 Jul 29;146(14):dev176776 |
1 | J:346123 Darrigrand JF, Salowka A, Torres-Cano A, Tapia-Rojo R, Zhu T, Garcia-Manyes S, Spagnoli FM, Acinar-ductal cell rearrangement drives branching morphogenesis of the murine pancreas in an IGF/PI3K-dependent manner. Dev Cell. 2024 Feb 5;59(3):326-338.e5 |
1 | J:104802 Deckelbaum RA, Majithia A, Booker T, Henderson JE, Loomis CA, The homeoprotein engrailed 1 has pleiotropic functions in calvarial intramembranous bone formation and remodeling. Development. 2006 Jan;133(1):63-74 |
1* | J:286571 Denda S, Reichardt LF, Muller U, Identification of osteopontin as a novel ligand for the integrin alpha8 beta1 and potential roles for this integrin-ligand interaction in kidney morphogenesis. Mol Biol Cell. 1998 Jun;9(6):1425-35 |
1* | J:77698 Eswarakumar VP, Monsonego-Ornan E, Pines M, Antonopoulou I, Morriss-Kay GM, Lonai P, The IIIc alternative of Fgfr2 is a positive regulator of bone formation. Development. 2002 Aug 15;129(16):3783-93 |
1 | J:347133 Funato N, Srivastava D, Shibata S, Yanagisawa H, TBX1 Regulates Chondrocyte Maturation in the Spheno-occipital Synchondrosis. J Dent Res. 2020 Sep;99(10):1182-1191 |
1 | J:185118 Galli GG, Honnens de Lichtenberg K, Carrara M, Hans W, Wuelling M, Mentz B, Multhaupt HA, Fog CK, Jensen KT, Rappsilber J, Vortkamp A, Coulton L, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Calogero RA, Couchman JR, Lund AH, Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone. PLoS Genet. 2012 May;8(5):e1002711 |
1 | J:150187 Guo X, Mak KK, Taketo MM, Yang Y, The Wnt/beta-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturation. PLoS One. 2009;4(6):e6067 |
1* | J:76230 Hajihosseini MK, Heath JK, Expression patterns of fibroblast growth factors-18 and -20 in mouse embryos is suggestive of novel roles in calvarial and limb development. Mech Dev. 2002 Apr;113(1):79-83 |
1 | J:146802 Harada M, Murakami H, Okawa A, Okimoto N, Hiraoka S, Nakahara T, Akasaka R, Shiraishi Y, Futatsugi N, Mizutani-Koseki Y, Kuroiwa A, Shirouzu M, Yokoyama S, Taiji M, Iseki S, Ornitz DM, Koseki H, FGF9 monomer-dimer equilibrium regulates extracellular matrix affinity and tissue diffusion. Nat Genet. 2009 Mar;41(3):289-98 |
1 | J:159025 Hattori T, Muller C, Gebhard S, Bauer E, Pausch F, Schlund B, Bosl MR, Hess A, Surmann-Schmitt C, von der Mark H, de Crombrugghe B, von der Mark K, SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification. Development. 2010 Mar;137(6):901-11 |
1 | J:176483 Holmes G, Bromage TG, Basilico C, The Sox2 high mobility group transcription factor inhibits mature osteoblast function in transgenic mice. Bone. 2011 Oct;49(4):653-61 |
1* | J:149465 Holmes G, Rothschild G, Roy UB, Deng CX, Mansukhani A, Basilico C, Early onset of craniosynostosis in an Apert mouse model reveals critical features of this pathology. Dev Biol. 2009 Apr 15;328(2):273-84 |
1 | J:237341 Houben A, Kostanova-Poliakova D, Weissenbock M, Graf J, Teufel S, von der Mark K, Hartmann C, beta-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis. Development. 2016 Oct 15;143(20):3826-3838 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:54095 Inada M, Yasui T, Nomura S, Miyake S, Deguchi K, Himeno M, Sato M, Yamagiwa H, Kimura T, Yasui N, Ochi T, Endo N, Kitamura Y, Kishimoto T, Komori T, Maturational disturbance of chondrocytes in Cbfa1-deficient mice. Dev Dyn. 1999 Apr;214(4):279-90 |
2* | J:43065 Iseki S, Wilkie AO, Heath JK, Ishimaru T, Eto K, Morriss-Kay GM, Fgfr2 and osteopontin domains in the developing skull vault are mutually exclusive and can be altered by locally applied FGF2. Development. 1997 Sep;124(17):3375-84 |
1 | J:153633 Ito T, Yadav N, Lee J, Furumatsu T, Yamashita S, Yoshida K, Taniguchi N, Hashimoto M, Tsuchiya M, Ozaki T, Lotz M, Bedford MT, Asahara H, Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC Dev Biol. 2009;9:47 |
1 | J:119288 Jacob AL, Smith C, Partanen J, Ornitz DM, Fibroblast growth factor receptor 1 signaling in the osteo-chondrogenic cell lineage regulates sequential steps of osteoblast maturation. Dev Biol. 2006 Aug 15;296(2):315-28 |
1 | J:233766 Jiang Q, Qin X, Kawane T, Komori H, Matsuo Y, Taniuchi I, Ito K, Izumi S, Komori T, Cbfb2 Isoform Dominates More Potent Cbfb1 and Is Required for Skeletal Development. J Bone Miner Res. 2016 Jul;31(7):1391-404 |
1* | J:300574 Jiang Q, Qin X, Yoshida CA, Komori H, Yamana K, Ohba S, Hojo H, Croix BS, Kawata-Matsuura VKS, Komori T, Antxr1, Which is a Target of Runx2, Regulates Chondrocyte Proliferation and Apoptosis. Int J Mol Sci. 2020 Mar 31;21(7):2425 |
1 | J:154990 Kang HS, Kim YS, ZeRuth G, Beak JY, Gerrish K, Kilic G, Sosa-Pineda B, Jensen J, Foley J, Jetten AM, Transcription factor Glis3, a novel critical player in the regulation of pancreatic beta-cell development and insulin gene expression. Mol Cell Biol. 2009 Dec;29(24):6366-79 |
1 | J:295492 Kawai M, Herrmann D, Fuchs A, Cheng S, Ferrer-Vaquer A, Gotz R, Driller K, Neubuser A, Ohura K, Fgfr1 conditional-knockout in neural crest cells induces heterotopic chondrogenesis and osteogenesis in mouse frontal bones. Med Mol Morphol. 2019 Sep;52(3):156-163 |
1 | J:108608 Kilic G, Wang J, Sosa-Pineda B, Osteopontin is a novel marker of pancreatic ductal tissues and of undifferentiated pancreatic precursors in mice. Dev Dyn. 2006 Jun;235(6):1659-67 |
1 | J:80669 Kundu M, Javed A, Jeon JP, Horner A, Shum L, Eckhaus M, Muenke M, Lian JB, Yang Y, Nuckolls GH, Stein GS, Liu PP, Cbfbeta interacts with Runx2 and has a critical role in bone development. Nat Genet. 2002 Dec;32(4):639-44 |
1* | J:60156 Lee K, Lanske B, Karaplis AC, Deeds JD, Kohno H, Nissenson RA, Kronenberg HM, Segre GV, Parathyroid hormone-related peptide delays terminal differentiation of chondrocytes during endochondral bone development. Endocrinology. 1996 Nov;137(11):5109-18 |
1 | J:319475 Liao C, Lu M, Hong Y, Mao C, Chen J, Ren C, Lin M, Chen W, Osteogenic and angiogenic profiles of the palatal process of the maxilla and the palatal process of the palatine bone. J Anat. 2022 Feb;240(2):385-397 |
1 | J:333798 Luo S, Liu Z, Bian Q, Wang X, Ectomesenchymal Six1 controls mandibular skeleton formation. Front Genet. 2023;14:1082911 |
1* | J:85738 MacLean HE, Kim JI, Glimcher MJ, Wang J, Kronenberg HM, Glimcher LH, Absence of transcription factor c-maf causes abnormal terminal differentiation of hypertrophic chondrocytes during endochondral bone development. Dev Biol. 2003 Oct 1;262(1):51-63 |
1* | J:74493 Maes C, Carmeliet P, Moermans K, Stockmans I, Smets N, Collen D, Bouillon R, Carmeliet G, Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF(164) and VEGF(188). Mech Dev. 2002 Feb;111(1-2):61-73 |
1 | J:296737 Matsuura VKSK, Yoshida CA, Komori H, Sakane C, Yamana K, Jiang Q, Komori T, Expression of a Constitutively Active Form of Hck in Chondrocytes Activates Wnt and Hedgehog Signaling Pathways, and Induces Chondrocyte Proliferation in Mice. Int J Mol Sci. 2020 Apr 12;21(8):2682 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1* | J:74179 Nikaido T, Yokoya S, Mori T, Hagino S, Iseki K, Zhang Y, Takeuchi M, Takaki H, Kikuchi S, Wanaka A, Expression of the novel transcription factor OASIS, which belongs to the CREB/ATF family, in mouse embryo with special reference to bone development. Histochem Cell Biol. 2001 Aug;116(2):141-8 |
2* | J:9026 Nomura S, Wills AJ, Edwards DR, Heath JK, Hogan BL, Developmental expression of 2ar (osteopontin) and SPARC (osteonectin) RNA as revealed by in situ hybridization. J Cell Biol. 1988 Feb;106(2):441-50 |
1 | J:75880 Ohbayashi N, Shibayama M, Kurotaki Y, Imanishi M, Fujimori T, Itoh N, Takada S, FGF18 is required for normal cell proliferation and differentiation during osteogenesis and chondrogenesis. Genes Dev. 2002 Apr 1;16(7):870-9 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1 | J:219841 Qin X, Jiang Q, Matsuo Y, Kawane T, Komori H, Moriishi T, Taniuchi I, Ito K, Kawai Y, Rokutanda S, Izumi S, Komori T, Cbfb regulates bone development by stabilizing runx family proteins. J Bone Miner Res. 2015 Apr;30(4):706-14 |
1 | J:299239 Qin X, Jiang Q, Nagano K, Moriishi T, Miyazaki T, Komori H, Ito K, Mark KV, Sakane C, Kaneko H, Komori T, Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts. PLoS Genet. 2020 Nov;16(11):e1009169 |
2* | J:76140 Shibata S, Fukada K, Suzuki S, Ogawa T, Yamashita Y, In situ hybridization and immunohistochemistry of bone sialoprotein and secreted phosphoprotein 1 (osteopontin) in the developing mouse mandibular condylar cartilage compared with limb bud cartilage. J Anat. 2002 Mar;200(Pt 3):309-20 |
1 | J:150837 Shim JH, Greenblatt MB, Xie M, Schneider MD, Zou W, Zhai B, Gygi S, Glimcher LH, TAK1 is an essential regulator of BMP signalling in cartilage. EMBO J. 2009 Jul 22;28(14):2028-41 |
1* | J:76263 Stricker S, Fundele R, Vortkamp A, Mundlos S, Role of Runx genes in chondrocyte differentiation. Dev Biol. 2002 May 1;245(1):95-108 |
1 | J:191584 Sueyoshi T, Yamamoto K, Akiyama H, Conditional deletion of Tgfbr2 in hypertrophic chondrocytes delays terminal chondrocyte differentiation. Matrix Biol. 2012 Jul;31(6):352-9 |
1 | J:171003 Sugito H, Shibukawa Y, Kinumatsu T, Yasuda T, Nagayama M, Yamada S, Minugh-Purvis N, Pacifici M, Koyama E, Ihh signaling regulates mandibular symphysis development and growth. J Dent Res. 2011 May;90(5):625-31 |
1 | J:351035 Tan Z, Chen P, Dong X, Guo S, Leung VYL, Cheung JPY, Chan D, Richardson SM, Hoyland JA, To MKT, Cheah KSE, Progenitor-like cells contributing to cellular heterogeneity in the nucleus pulposus are lost in intervertebral disc degeneration. Cell Rep. 2024 Jun 25;43(6):114342 |
1 | J:125052 Taniguchi N, Yoshida K, Ito T, Tsuda M, Mishima Y, Furumatsu T, Ronfani L, Abeyama K, Kawahara K, Komiya S, Maruyama I, Lotz M, Bianchi ME, Asahara H, Stage-specific secretion of HMGB1 in cartilage regulates endochondral ossification. Mol Cell Biol. 2007 Aug;27(16):5650-63 |
1 | J:161451 Villavicencio-Lorini P, Kuss P, Friedrich J, Haupt J, Farooq M, Turkmen S, Duboule D, Hecht J, Mundlos S, Homeobox genes d11-d13 and a13 control mouse autopod cortical bone and joint formation. J Clin Invest. 2010 Jun 1;120(6):1994-2004 |
1 | J:101174 Wang Y, Xiao R, Yang F, Karim BO, Iacovelli AJ, Cai J, Lerner CP, Richtsmeier JT, Leszl JM, Hill CA, Yu K, Ornitz DM, Elisseeff J, Huso DL, Jabs EW, Abnormalities in cartilage and bone development in the Apert syndrome FGFR2(+/S252W) mouse. Development. 2005 Aug;132(15):3537-48 |
1* | J:326545 Watanabe R, Matsugaki A, Ishimoto T, Ozasa R, Matsumoto T, Nakano T, A Novel Ex Vivo Bone Culture Model for Regulation of Collagen/Apatite Preferential Orientation by Mechanical Loading. Int J Mol Sci. 2022 Jul 4;23(13) |
1 | J:172737 Wilson DG, Phamluong K, Li L, Sun M, Cao TC, Liu PS, Modrusan Z, Sandoval WN, Rangell L, Carano RA, Peterson AS, Solloway MJ, Global defects in collagen secretion in a Mia3/TANGO1 knockout mouse. J Cell Biol. 2011 May 30;193(5):935-51 |
1 | J:362739 Wu Y, Qin K, Xu Y, Rajhans S, Vo T, Lopez KM, Liu J, Nipper MH, Deng J, Yin X, Ramjit LR, Ye Z, Luan Y, Arda HE, Wang P, Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation. Elife. 2024 Jul 25;13 |
1* | J:307192 Yadav PS, Feng S, Cong Q, Kim H, Liu Y, Yang Y, Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118 |
1 | J:283626 Yin L, Du X, Li C, Xu X, Chen Z, Su N, Zhao L, Qi H, Li F, Xue J, Yang J, Jin M, Deng C, Chen L, A Pro253Arg mutation in fibroblast growth factor receptor 2 (Fgfr2) causes skeleton malformation mimicking human Apert syndrome by affecting both chondrogenesis and osteogenesis. Bone. 2008 Apr;42(4):631-43 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
1* | J:90391 Yu K, Xu J, Liu Z, Sosic D, Shao J, Olson EN, Towler DA, Ornitz DM, Conditional inactivation of FGF receptor 2 reveals an essential role for FGF signaling in the regulation of osteoblast function and bone growth. Development. 2003 Jul;130(13):3063-74 |
1 | J:202210 Zhang X, Ting K, Pathmanathan D, Ko T, Chen W, Chen F, Lee H, James AW, Siu RK, Shen J, Culiat CT, Soo C, Calvarial cleidocraniodysplasia-like defects with ENU-induced Nell-1 deficiency. J Craniofac Surg. 2012 Jan;23(1):61-6 |
1 | J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39 |
Spp2 secreted phosphoprotein 2 (Synonyms: 0610038O04Rik, spp24) | |
Results | Reference |
1 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
Sppl3 signal peptide peptidase 3 (Synonyms: 4833416I09Rik, Usmg3) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Spred1 sprouty protein with EVH-1 domain 1, related sequence (Synonyms: 5730461F13Rik, Spred-1) | |
Results | Reference |
1* | J:168653 Sylvestersen KB, Herrera PL, Serup P, Rescan C, Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):105-11 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Spred2 sprouty-related EVH1 domain containing 2 (Synonyms: Spred-2) | |
Results | Reference |
1* | J:168653 Sylvestersen KB, Herrera PL, Serup P, Rescan C, Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):105-11 |
Sprr1a small proline-rich protein 1A | |
Results | Reference |
1* | J:129949 Cui CY, Kunisada M, Esibizione D, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet. 2007 Nov 1;16(21):2583-90 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
2* | J:62093 Marshall D, Hardman MJ, Byrne C, SPRR1 gene induction and barrier formation occur as coordinated moving fronts in terminally differentiating epithelia. J Invest Dermatol. 2000 May;114(5):967-75 |
1* | J:234993 Nishiguchi Y, Ohmoto M, Koki J, Enomoto T, Kominami R, Matsumoto I, Hirota J, Bcl11b/Ctip2 is required for development of lingual papillae in mice. Dev Biol. 2016 Aug 1;416(1):98-110 |
Sprr2d small proline-rich protein 2D | |
Results | Reference |
1 | J:321162 Boix J, Carceller E, Sevilla LM, Marcos-Garces V, Perez P, The mineralocorticoid receptor plays a transient role in mouse skin development. Exp Dermatol. 2016 Jan;25(1):69-71 |
1* | J:191045 Huebner AJ, Dai D, Morasso M, Schmidt EE, Schafer M, Werner S, Roop DR, Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero. Dev Cell. 2012 Dec 11;23(6):1238-46 |
1 | J:65187 Koch PJ, de Viragh PA, Scharer E, Bundman D, Longley MA, Bickenbach J, Kawachi Y, Suga Y, Zhou Z, Huber M, Hohl D, Kartasova T, Jarnik M, Steven AC, Roop DR, Lessons from loricrin-deficient mice. Compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein. J Cell Biol. 2000 Oct 16;151(2):389-400 |
1 | J:182938 Sevilla LM, Bayo P, Latorre V, Sanchis A, Perez P, Glucocorticoid receptor regulates overlapping and differential gene subsets in developing and adult skin. Mol Endocrinol. 2010 Nov;24(11):2166-78 |
Sprr2h small proline-rich protein 2H | |
Results | Reference |
1* | J:191045 Huebner AJ, Dai D, Morasso M, Schmidt EE, Schafer M, Werner S, Roop DR, Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero. Dev Cell. 2012 Dec 11;23(6):1238-46 |
Spry1 sprouty RTK signaling antagonist 1 (Synonyms: sprouty 1, sprouty1) | |
Results | Reference |
1 | J:240770 Gobius I, Morcom L, Suarez R, Bunt J, Bukshpun P, Reardon W, Dobyns WB, Rubenstein JL, Barkovich AJ, Sherr EH, Richards LJ, Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum. Cell Rep. 2016 Oct 11;17(3):735-747 |
1 | J:235521 Joo A, Long R, Cheng Z, Alexander C, Chang W, Klein OD, Sprouty2 regulates endochondral bone formation by modulation of RTK and BMP signaling. Bone. 2016 Jul;88:170-9 |
1 | J:130572 Klein OD, Lyons DB, Balooch G, Marshall GW, Basson MA, Peterka M, Boran T, Peterkova R, Martin GR, An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development. 2008 Jan;135(2):377-85 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:356701 Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD, Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr;91(4):387-93 |
1 | J:98303 Shim K, Minowada G, Coling DE, Martin GR, Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling. Dev Cell. 2005 Apr;8(4):553-64 |
1 | J:345586 Wazin F, Lovicu FJ, Conditional Ablation of Spred1 and Spred2 in the Eye Lens Negatively Impacts Its Development and Growth. Cells. 2024 Feb 6;13(4) |
1 | J:173529 Yu T, Yaguchi Y, Echevarria D, Martinez S, Basson MA, Sprouty genes prevent excessive FGF signalling in multiple cell types throughout development of the cerebellum. Development. 2011 Jul;138(14):2957-68 |
Spry2 sprouty RTK signaling antagonist 2 (Synonyms: sprouty2) | |
Results | Reference |
1 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
1 | J:195145 Amaniti EM, Hasenpusch-Theil K, Li Z, Magnani D, Kessaris N, Mason JO, Theil T, Gli3 is required in Emx1(+) progenitors for the development of the corpus callosum. Dev Biol. 2013 Apr 15;376(2):113-24 |
1 | J:240770 Gobius I, Morcom L, Suarez R, Bunt J, Bukshpun P, Reardon W, Dobyns WB, Rubenstein JL, Barkovich AJ, Sherr EH, Richards LJ, Astroglial-Mediated Remodeling of the Interhemispheric Midline Is Required for the Formation of the Corpus Callosum. Cell Rep. 2016 Oct 11;17(3):735-747 |
1 | J:117235 Hayashi T, Cunningham D, Bermingham-McDonogh O, Loss of Fgfr3 leads to excess hair cell development in the mouse organ of Corti. Dev Dyn. 2007 Feb;236(2):525-33 |
1 | J:233686 Jia WJ, Jiang S, Tang QL, Shen D, Xue B, Ning W, Li CJ, Geranylgeranyl Diphosphate Synthase Modulates Fetal Lung Branching Morphogenesis Possibly through Controlling K-Ras Prenylation. Am J Pathol. 2016 Jun;186(6):1454-65 |
1 | J:235521 Joo A, Long R, Cheng Z, Alexander C, Chang W, Klein OD, Sprouty2 regulates endochondral bone formation by modulation of RTK and BMP signaling. Bone. 2016 Jul;88:170-9 |
1 | J:130572 Klein OD, Lyons DB, Balooch G, Marshall GW, Basson MA, Peterka M, Boran T, Peterkova R, Martin GR, An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development. 2008 Jan;135(2):377-85 |
1 | J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670 |
1 | J:217046 Magnani D, Hasenpusch-Theil K, Benadiba C, Yu T, Basson MA, Price DJ, Lebrand C, Theil T, Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Cereb Cortex. 2014 Jan;24(1):186-98 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:356701 Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD, Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr;91(4):387-93 |
1 | J:98303 Shim K, Minowada G, Coling DE, Martin GR, Sprouty2, a mouse deafness gene, regulates cell fate decisions in the auditory sensory epithelium by antagonizing FGF signaling. Dev Cell. 2005 Apr;8(4):553-64 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:168653 Sylvestersen KB, Herrera PL, Serup P, Rescan C, Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):105-11 |
1 | J:345586 Wazin F, Lovicu FJ, Conditional Ablation of Spred1 and Spred2 in the Eye Lens Negatively Impacts Its Development and Growth. Cells. 2024 Feb 6;13(4) |
1 | J:173529 Yu T, Yaguchi Y, Echevarria D, Martinez S, Basson MA, Sprouty genes prevent excessive FGF signalling in multiple cell types throughout development of the cerebellum. Development. 2011 Jul;138(14):2957-68 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
Spry3 sprouty RTK signaling antagonist 3 (Synonyms: LOC236576, sprouty3) | |
Results | Reference |
1* | J:356701 Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD, Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr;91(4):387-93 |
1* | J:168653 Sylvestersen KB, Herrera PL, Serup P, Rescan C, Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):105-11 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
Spry4 sprouty RTK signaling antagonist 4 (Synonyms: A030006O18Rik, sprouty4) | |
Results | Reference |
1 | J:235521 Joo A, Long R, Cheng Z, Alexander C, Chang W, Klein OD, Sprouty2 regulates endochondral bone formation by modulation of RTK and BMP signaling. Bone. 2016 Jul;88:170-9 |
1 | J:130572 Klein OD, Lyons DB, Balooch G, Marshall GW, Basson MA, Peterka M, Boran T, Peterkova R, Martin GR, An FGF signaling loop sustains the generation of differentiated progeny from stem cells in mouse incisors. Development. 2008 Jan;135(2):377-85 |
1 | J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670 |
1* | J:160766 Porntaveetus T, Oommen S, Sharpe PT, Ohazama A, Expression of Fgf signalling pathway related genes during palatal rugae development in the mouse. Gene Expr Patterns. 2010 Jun;10(4-5):193-8 |
1* | J:356701 Purcell P, Jheon A, Vivero MP, Rahimi H, Joo A, Klein OD, Spry1 and spry2 are essential for development of the temporomandibular joint. J Dent Res. 2012 Apr;91(4):387-93 |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
1* | J:168653 Sylvestersen KB, Herrera PL, Serup P, Rescan C, Fgf9 signalling stimulates Spred and Sprouty expression in embryonic mouse pancreas mesenchyme. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):105-11 |
1 | J:173529 Yu T, Yaguchi Y, Echevarria D, Martinez S, Basson MA, Sprouty genes prevent excessive FGF signalling in multiple cell types throughout development of the cerebellum. Development. 2011 Jul;138(14):2957-68 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
Spta1 spectrin alpha, erythrocytic 1 (Synonyms: erythroid, ihj, Spna-1, Spna1) | |
Results | Reference |
1 | J:216288 Jones C, Qian D, Kim SM, Li S, Ren D, Knapp L, Sprinzak D, Avraham KB, Matsuzaki F, Chi F, Chen P, Ankrd6 is a mammalian functional homolog of Drosophila planar cell polarity gene diego and regulates coordinated cellular orientation in the mouse inner ear. Dev Biol. 2014 Nov 1;395(1):62-72 |
Sptan1 spectrin alpha, non-erythrocytic 1 (Synonyms: 2610027H02Rik, alpha-fodrin, alphaII-spectrin, Spna-2, Spna2) | |
Results | Reference |
1 | J:119451 Deans MR, Antic D, Suyama K, Scott MP, Axelrod JD, Goodrich LV, Asymmetric distribution of Prickle-like 2 reveals an early underlying polarization of vestibular sensory epithelia in the inner ear. J Neurosci. 2007 Mar 21;27(12):3139-47 |
Sptbn1 spectrin beta, non-erythrocytic 1 (Synonyms: 9930031C03Rik, beta fodrin, brain spectrin, elf1, elf3, non-erythrocytic, spectrin G, Spnb-2, Spnb2) | |
Results | Reference |
1* | J:219548 Lim JA, Baek HJ, Jang MS, Choi EK, Lee YM, Lee SJ, Lim SC, Kim JY, Kim TH, Kim HS, Mishra L, Kim SS, Loss of beta2-spectrin prevents cardiomyocyte differentiation and heart development. Cardiovasc Res. 2014 Jan 1;101(1):39-47 |
2 | J:52539 Mishra L, Cai T, Yu P, Monga SP, Mishra B, Elf3 encodes a novel 200-kD beta-spectrin: role in liver development. Oncogene. 1999 Jan 14;18(2):353-64 |
Sptbn2 spectrin beta, non-erythrocytic 2 (Synonyms: Spnb3) | |
Results | Reference |
1 | J:330450 Ji YR, Tona Y, Wafa T, Christman ME, Tourney ED, Jiang T, Ohta S, Cheng H, Fitzgerald T, Fritzsch B, Jones SM, Cullen KE, Wu DK, Function of bidirectional sensitivity in the otolith organs established by transcription factor Emx2. Nat Commun. 2022 Oct 24;13(1):6330 |
Sptlc1 serine palmitoyltransferase, long chain base subunit 1 (Synonyms: Lcb1, Spt1) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Sptlc2 serine palmitoyltransferase, long chain base subunit 2 (Synonyms: LCB2, Spt2) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Sptlc3 serine palmitoyltransferase, long chain base subunit 3 (Synonyms: C130053K05Rik) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Sqstm1 sequestosome 1 (Synonyms: A170, OSF-6, Osi, p62, STAP) | |
Results | Reference |
2 | J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410 |
1 | J:342871 Xiang J, Pompetti AJ, Faranda AP, Wang Y, Novo SG, Li DW, Duncan MK, ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment. Cells. 2023 Nov 16;12(22) |
Src Rous sarcoma oncogene (Synonyms: pp60c-src) | |
Results | Reference |
1 | J:109820 Arnaud L, Ballif BA, Forster E, Cooper JA, Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development. Curr Biol. 2003 Jan 8;13(1):9-17 |
1 | J:101055 Kuo G, Arnaud L, Kronstad-O'Brien P, Cooper JA, Absence of Fyn and Src causes a reeler-like phenotype. J Neurosci. 2005 Sep 14;25(37):8578-86 |
1 | J:178367 Slamon DJ, Cline MJ, Expression of cellular oncogenes during embryonic and fetal development of the mouse. Proc Natl Acad Sci U S A. 1984 Nov;81(22):7141-5 |
1* | J:55945 Wang JP, Chuang SM, Shen CL, Chen ST, Expression of Src family during development of the mouse nervous system. Biomed Res. 1998 OCT;19(5):315-325 |
Srd5a1 steroid 5 alpha-reductase 1 (Synonyms: 0610031P22Rik, 4930435F02Rik, Srd5a-1) | |
Results | Reference |
1 | J:205146 Praktiknjo SD, Llamas B, Scott-Boyer MP, Picard S, Robert F, Langlais D, Haibe-Kains B, Faubert D, Silversides DW, Deschepper CF, Novel effects of chromosome Y on cardiac regulation, chromatin remodeling, and neonatal programming in male mice. Endocrinology. 2013 Dec;154(12):4746-56 |
Srd5a2 steroid 5 alpha-reductase 2 (Synonyms: 5ART2) | |
Results | Reference |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1* | J:192625 Keil KP, Mehta V, Branam AM, Abler LL, Buresh-Stiemke RA, Joshi PS, Schmitz CT, Marker PC, Vezina CM, Wnt inhibitory factor 1 (Wif1) is regulated by androgens and enhances androgen-dependent prostate development. Endocrinology. 2012 Dec;153(12):6091-103 |
1* | J:354175 Ueda Y, Suzuki K, Kajimoto M, Fujimoto K, Mahendroo M, Ema M, Yamada G, Hara I, Possible testosterone redundancy for 5alpha-dihydrotestosterone in the masculinization of mouse external genitalia. Exp Anim. 2022 Nov 10;71(4):451-459 |
Srebf1 sterol regulatory element binding transcription factor 1 (Synonyms: ADD-1, bHLHd1, SREBP-1, SREBP1, SREBP-1a, SREBP-1c, SREBP1c) | |
Results | Reference |
1 | J:200565 Antony N, Weir JR, McDougall AR, Mantamadiotis T, Meikle PJ, Cole TJ, Bird AD, cAMP response element binding protein1 is essential for activation of steroyl co-enzyme a desaturase 1 (Scd1) in mouse lung type II epithelial cells. PLoS One. 2013;8(4):e59763 |
Srebf2 sterol regulatory element binding factor 2 (Synonyms: bHLHd2, lop13, nuc, SREBP-2, SREBP2, SREBP2gc) | |
Results | Reference |
1 | J:264124 Tsushima H, Tang YJ, Puviindran V, Hsu SC, Nadesan P, Yu C, Zhang H, Mirando AJ, Hilton MJ, Alman BA, Intracellular biosynthesis of lipids and cholesterol by Scap and Insig in mesenchymal cells regulates long bone growth and chondrocyte homeostasis. Development. 2018 Jul 9;145(13):dev162396 |
Srf serum response factor | |
Results | Reference |
1 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1 | J:183651 Kim EY, Chen L, Ma Y, Yu W, Chang J, Moskowitz IP, Wang J, Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J Mol Cell Cardiol. 2012 Mar;52(3):638-49 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
2* | J:267238 Sun K, Battle MA, Misra RP, Duncan SA, Hepatocyte expression of serum response factor is essential for liver function, hepatocyte proliferation and survival, and postnatal body growth in mice. Hepatology. 2009 May;49(5):1645-54 |
Srgap1 SLIT-ROBO Rho GTPase activating protein 1 (Synonyms: 4930572H05Rik, Arhgap13) | |
Results | Reference |
1* | J:146175 Bacon C, Endris V, Rappold G, Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system. J Comp Neurol. 2009 Mar 10;513(2):224-36 |
1 | J:240644 Fan X, Yang H, Kumar S, Tumelty KE, Pisarek-Horowitz A, Rasouly HM, Sharma R, Chan S, Tyminski E, Shamashkin M, Belghasem M, Henderson JM, Coyle AJ, Salant DJ, Berasi SP, Lu W, SLIT2/ROBO2 signaling pathway inhibits nonmuscle myosin IIA activity and destabilizes kidney podocyte adhesion. JCI Insight. 2016 Nov 17;1(19):e86934 |
1 | J:333727 Rogg M, Maier JI, Dotzauer R, Artelt N, Kretz O, Helmstadter M, Abed A, Sammarco A, Sigle A, Sellung D, Dinse P, Reiche K, Yasuda-Yamahara M, Biniossek ML, Walz G, Werner M, Endlich N, Schilling O, Huber TB, Schell C, SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance. J Am Soc Nephrol. 2021 Mar;32(3):563-579 |
Srgap2 SLIT-ROBO Rho GTPase activating protein 2 (Synonyms: 9930124L22Rik, FBP2, Fnbp2) | |
Results | Reference |
1* | J:146175 Bacon C, Endris V, Rappold G, Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system. J Comp Neurol. 2009 Mar 10;513(2):224-36 |
1 | J:333727 Rogg M, Maier JI, Dotzauer R, Artelt N, Kretz O, Helmstadter M, Abed A, Sammarco A, Sigle A, Sellung D, Dinse P, Reiche K, Yasuda-Yamahara M, Biniossek ML, Walz G, Werner M, Endlich N, Schilling O, Huber TB, Schell C, SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance. J Am Soc Nephrol. 2021 Mar;32(3):563-579 |
Srgap3 SLIT-ROBO Rho GTPase activating protein 3 (Synonyms: Arhgap14, D130026O08Rik, mKIAA0411) | |
Results | Reference |
1* | J:146175 Bacon C, Endris V, Rappold G, Dynamic expression of the Slit-Robo GTPase activating protein genes during development of the murine nervous system. J Comp Neurol. 2009 Mar 10;513(2):224-36 |
1 | J:333727 Rogg M, Maier JI, Dotzauer R, Artelt N, Kretz O, Helmstadter M, Abed A, Sammarco A, Sigle A, Sellung D, Dinse P, Reiche K, Yasuda-Yamahara M, Biniossek ML, Walz G, Werner M, Endlich N, Schilling O, Huber TB, Schell C, SRGAP1 Controls Small Rho GTPases To Regulate Podocyte Foot Process Maintenance. J Am Soc Nephrol. 2021 Mar;32(3):563-579 |
Srr serine racemase (Synonyms: M100034, Rgsc34) | |
Results | Reference |
1 | J:336861 Folorunso OO, Brown SE, Baruah J, Harvey TL, Jami SA, Radzishevsky I, Wolosker H, McNally JM, Gray JA, Vasudevan A, Balu DT, D-serine availability modulates prefrontal cortex inhibitory interneuron development and circuit maturation. Sci Rep. 2023 Jun 13;13(1):9595 |
Srrm3 serine/arginine repetitive matrix 3 (Synonyms: 2900083I11Rik, SRm300-like, Srrm2l) | |
Results | Reference |
1* | J:281311 Nakano Y, Wiechert S, Banfi B, Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8 |
1 | J:305017 Nakano Y, Wiechert S, Fritzsch B, Banfi B, Inhibition of a transcriptional repressor rescues hearing in a splicing factor-deficient mouse. Life Sci Alliance. 2020 Dec;3(12) |
Srrm4 serine/arginine repetitive matrix 4 (Synonyms: 1500001A10Rik, B230202K19Rik, bv, flopsy, fp, mKIAA1853, nSR100) | |
Results | Reference |
2* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
1* | J:281311 Nakano Y, Wiechert S, Banfi B, Overlapping Activities of Two Neuronal Splicing Factors Switch the GABA Effect from Excitatory to Inhibitory by Regulating REST. Cell Rep. 2019 Apr 16;27(3):860-871.e8 |
1 | J:221584 Quesnel-Vallieres M, Irimia M, Cordes SP, Blencowe BJ, Essential roles for the splicing regulator nSR100/SRRM4 during nervous system development. Genes Dev. 2015 Apr 1;29(7):746-59 |
Srsf1 serine and arginine-rich splicing factor 1 (Synonyms: 1110054N12Rik, 5730507C05Rik, 6330415C05Rik, Sfrs1) | |
Results | Reference |
1 | J:341968 Weber AI, Parthasarathy S, Borisova E, Epifanova E, Preussner M, Rusanova A, Ambrozkiewicz MC, Bessa P, Newman AG, Muller L, Schaal H, Heyd F, Tarabykin V, Srsf1 and Elavl1 act antagonistically on neuronal fate choice in the developing neocortex by controlling TrkC receptor isoform expression. Nucleic Acids Res. 2023 Oct 27;51(19):10218-10237 |
1* | J:344233 Wu C, Liu H, Zhan Z, Zhang X, Zhang M, You J, Ma J, Unveiling dysregulated lncRNAs and networks in non-syndromic cleft lip with or without cleft palate pathogenesis. Sci Rep. 2024 Jan 10;14(1):1047 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Srsf2 serine and arginine-rich splicing factor 2 (Synonyms: D11Wsu175e, MRF-1, SC35, Sfrs10, Sfrs2) | |
Results | Reference |
1 | J:206588 Mardaryev AN, Gdula MR, Yarker JL, Emelianov VN, Poterlowicz K, Sharov AA, Sharova TY, Scarpa JA, Chambon P, Botchkarev VA, Fessing MY, p63 and Brg1 control developmentally regulated higher-order chromatin remodelling at the epidermal differentiation complex locus in epidermal progenitor cells. Development. 2014 Jan;141(1):101-11 |
2 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
Srsf3 serine and arginine-rich splicing factor 3 (Synonyms: Sfrs3, X16) | |
Results | Reference |
2* | J:314887 Zhang M, Zhou J, Jiao L, Xu L, Hou L, Yin B, Qiang B, Lu S, Shu P, Peng X, Long Non-coding RNA T-uc.189 Modulates Neural Progenitor Cell Fate by Regulating Srsf3 During Mouse Cerebral Cortex Development. Front Neurosci. 2021;15:709684 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Srsf5 serine and arginine-rich splicing factor 5 (Synonyms: Sfrs5) | |
Results | Reference |
1 | J:311867 Zhang X, Wang Z, Xu Q, Chen Y, Liu W, Zhong T, Li H, Quan C, Zhang L, Cui CP, Splicing factor Srsf5 deletion disrupts alternative splicing and causes noncompaction of ventricular myocardium. iScience. 2021 Oct 22;24(10):103097 |
Srsf6 serine and arginine-rich splicing factor 6 (Synonyms: 1210001E11Rik, Sfrs6) | |
Results | Reference |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Srsf7 serine and arginine-rich splicing factor 7 (Synonyms: 9430065L19Rik, 9G8, NX-96, Sfrs7) | |
Results | Reference |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Srsf11 serine and arginine-rich splicing factor 11 (Synonyms: 0610009J05Rik, 2610019N13Rik, Sfrs11) | |
Results | Reference |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Sry sex determining region of Chr Y (Synonyms: Tdf, Tdy) | |
Results | Reference |
1* | J:10838 Koopman P, Munsterberg A, Capel B, Vivian N, Lovell-Badge R, Expression of a candidate sex-determining gene during mouse testis differentiation. Nature. 1990 Nov 29;348(6300):450-2 |
1* | J:21125 Lee CH, Taketo T, Normal onset, but prolonged expression, of Sry gene in the B6.YDOM sex-reversed mouse gonad. Dev Biol. 1994 Oct;165(2):442-52 |
1 | J:67267 Perera EM, Martin H, Seeherunvong T, Kos L, Hughes IA, Hawkins JR, Berkovitz GD, Tescalcin, a novel gene encoding a putative EF-hand Ca(2+)-binding protein, Col9a3, and renin are expressed in the mouse testis during the early stages of gonadal differentiation. Endocrinology. 2001 Jan;142(1):455-63 |
Ss18 SS18, subunit of BAF chromatin remodeling complex (Synonyms: Ssxt) | |
Results | Reference |
1 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
Ss18l1 SS18, nBAF chromatin remodeling complex subunit like 1 (Synonyms: A230053O16Rik, CREST) | |
Results | Reference |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
1 | J:153169 Kouznetsova A, Wang H, Bellani M, Camerini-Otero RD, Jessberger R, Hoog C, BRCA1-mediated chromatin silencing is limited to oocytes with a small number of asynapsed chromosomes. J Cell Sci. 2009 Jul 15;122(Pt 14):2446-52 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1 | J:203746 Shin YH, McGuire MM, Rajkovic A, Mouse HORMAD1 is a meiosis i checkpoint protein that modulates DNA double- strand break repair during female meiosis. Biol Reprod. 2013 Aug;89(2):29 |
1 | J:194101 Yamaguchi S, Hong K, Liu R, Shen L, Inoue A, Diep D, Zhang K, Zhang Y, Tet1 controls meiosis by regulating meiotic gene expression. Nature. 2012 Dec 20;492(7429):443-7 |
Ss18l2 SS18, nBAF chromatin remodeling complex subunit like 2 (Synonyms: 1110020I04Rik, Band 47B, Deb1) | |
Results | Reference |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
Ssbp2 single-stranded DNA binding protein 2 (Synonyms: 1500004K09Rik, 2310079I02Rik, 9330163K02Rik, A830008M03Rik, Hspc116, Ssdp2) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Ssr1 signal sequence receptor, alpha (Synonyms: SSR, TRAPalpha) | |
Results | Reference |
1 | J:115006 Mesbah K, Camus A, Babinet C, Barra J, Mutation in the Trapalpha/Ssr1 gene, encoding translocon-associated protein alpha, results in outflow tract morphogenetic defects. Mol Cell Biol. 2006 Oct;26(20):7760-71 |
Sst somatostatin (Synonyms: preprosomatostatin, Smst, SOM, SRIF) | |
Results | Reference |
1 | J:156329 Anderson KR, Torres CA, Solomon K, Becker TC, Newgard CB, Wright CV, Hagman J, Sussel L, Cooperative transcriptional regulation of the essential pancreatic islet gene NeuroD1 (beta2) by Nkx2.2 and neurogenin 3. J Biol Chem. 2009 Nov 6;284(45):31236-48 |
2* | J:109247 Bates CM, Kegg H, Grady S, Expression of somatostatin in the adult and developing mouse kidney. Kidney Int. 2004 Nov;66(5):1785-93 |
1 | J:119559 Bouwman J, Spijker S, Schut D, Wachtler B, Ylstra B, Smit AB, Verhage M, Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse. J Neurochem. 2006 Oct;99(1):84-96 |
1 | J:116552 Brissova M, Shostak A, Shiota M, Wiebe PO, Poffenberger G, Kantz J, Chen Z, Carr C, Jerome WG, Chen J, Baldwin HS, Nicholson W, Bader DM, Jetton T, Gannon M, Powers AC, Pancreatic islet production of vascular endothelial growth factor--a is essential for islet vascularization, revascularization, and function. Diabetes. 2006 Nov;55(11):2974-85 |
1* | J:196346 Burgold T, Voituron N, Caganova M, Tripathi PP, Menuet C, Tusi BK, Spreafico F, Bevengut M, Gestreau C, Buontempo S, Simeone A, Kruidenier L, Natoli G, Casola S, Hilaire G, Testa G, The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival. Cell Rep. 2012 Nov 29;2(5):1244-58 |
1 | J:220324 De Vas MG, Kopp JL, Heliot C, Sander M, Cereghini S, Haumaitre C, Hnf1b controls pancreas morphogenesis and the generation of Ngn3+ endocrine progenitors. Development. 2015 Mar 1;142(5):871-82 |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:163224 Garcia-Lopez M, Abellan A, Legaz I, Rubenstein JL, Puelles L, Medina L, Histogenetic compartments of the mouse centromedial and extended amygdala based on gene expression patterns during development. J Comp Neurol. 2008 Jan 1;506(1):46-74 |
1* | J:152922 Golson ML, Le Lay J, Gao N, Bramswig N, Loomes KM, Oakey R, May CL, White P, Kaestner KH, Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas. Mech Dev. 2009 Aug-Sep;126(8-9):687-99 |
1 | J:89548 Goshu E, Jin H, Lovejoy J, Marion JF, Michaud JL, Fan CM, Sim2 contributes to neuroendocrine hormone gene expression in the anterior hypothalamus. Mol Endocrinol. 2004 May;18(5):1251-62 |
1 | J:134078 Hezel AF, Gurumurthy S, Granot Z, Swisa A, Chu GC, Bailey G, Dor Y, Bardeesy N, Depinho RA, Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. Mol Cell Biol. 2008 Apr;28(7):2414-25 |
1 | J:199638 Huang T, Hu J, Wang B, Nie Y, Geng J, Cheng L, Tlx3 controls cholinergic transmitter and Peptide phenotypes in a subset of prenatal sympathetic neurons. J Neurosci. 2013 Jun 26;33(26):10667-75 |
2 | J:257425 Kim DS, Song L, Wang J, Wu H, Gu G, Sugi Y, Li Z, Wang H, GRP94 Is an Essential Regulator of Pancreatic beta-Cell Development, Mass, and Function in Male Mice. Endocrinology. 2018 Feb 1;159(2):1062-1073 |
1* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
1 | J:263715 Lee B, Kim J, An T, Kim S, Patel EM, Raber J, Lee SK, Lee S, Lee JW, Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons. Nat Commun. 2018 May 23;9(1):2026 |
1 | J:237344 Lee B, Lee S, Lee SK, Lee JW, The LIM-homeobox transcription factor Isl1 plays crucial roles in the development of multiple arcuate nucleus neurons. Development. 2016 Oct 15;143(20):3763-3773 |
1 | J:272578 Liu J, Banerjee A, Herring CA, Attalla J, Hu R, Xu Y, Shao Q, Simmons AJ, Dadi PK, Wang S, Jacobson DA, Liu B, Hodges E, Lau KS, Gu G, Neurog3-Independent Methylation Is the Earliest Detectable Mark Distinguishing Pancreatic Progenitor Identity. Dev Cell. 2019 Jan 7;48(1):49-63.e7 |
3 | J:290417 Lorberbaum DS, Kishore S, Rosselot C, Sarbaugh D, Brooks EP, Aragon E, Xuan S, Simon O, Ghosh D, Mendelsohn C, Gadue P, Sussel L, Retinoic acid signaling within pancreatic endocrine progenitors regulates mouse and human beta cell specification. Development. 2020 Jun 22;147(12):dev189977 |
1 | J:62160 Miettinen PJ, Huotari M, Koivisto T, Ustinov J, Palgi J, Rasilainen S, Lehtonen E, Keski-Oja J, Otonkoski T, Impaired migration and delayed differentiation of pancreatic islet cells in mice lacking EGF-receptors. Development. 2000 Jun;127(12):2617-27 |
1 | J:321229 Murakami-Kawaguchi S, Takasawa S, Onogawa T, Nata K, Itaya-Hironaka A, Sakuramoto-Tsuchida S, Yamauchi A, Ota H, Takeda M, Kato M, Okamoto H, Expression of Ins1 and Ins2 genes in mouse fetal liver. Cell Tissue Res. 2014 Feb;355(2):303-14 |
1* | J:263835 Newman EA, Kim DW, Wan J, Wang J, Qian J, Blackshaw S, Foxd1 is required for terminal differentiation of anterior hypothalamic neuronal subtypes. Dev Biol. 2018 Jul 15;439(2):102-111 |
1 | J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461 |
1 | J:239946 Pan FC, Brissova M, Powers AC, Pfaff S, Wright CV, Inactivating the permanent neonatal diabetes gene Mnx1 switches insulin-producing beta-cells to a delta-like fate and reveals a facultative proliferative capacity in aged beta-cells. Development. 2015 Nov 01;142(21):3637-48 |
1* | J:224572 Pombero A, Martinez S, The alpha2-subunit of the nicotinic cholinergic receptor is specifically expressed in medial subpallium-derived cells of mammalian amygdala. J Comp Neurol. 2015 Aug 1;523(11):1608-21 |
1 | J:225813 Puelles L, Morales-Delgado N, Merchan P, Castro-Robles B, Martinez-de-la-Torre M, Diaz C, Ferran JL, Radial and tangential migration of telencephalic somatostatin neurons originated from the mouse diagonal area. Brain Struct Funct. 2016 Jul;221(6):3027-65 |
1* | J:146286 Real MA, Heredia R, Labrador Mdel C, Davila JC, Guirado S, Expression of somatostatin and neuropeptide Y in the embryonic, postnatal, and adult mouse amygdalar complex. J Comp Neurol. 2009 Apr 1;513(4):335-48 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
1 | J:357469 Sivori M, Dempsey B, Chettouh Z, Boismoreau F, Ayerdi M, et al., The pelvic organs receive no parasympathetic innervation. Elife. 2024;15 |
1 | J:151981 Spence JR, Lange AW, Lin SC, Kaestner KH, Lowy AM, Kim I, Whitsett JA, Wells JM, Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell. 2009 Jul;17(1):62-74 |
1 | J:147764 Svensson P, Bergqvist I, Norlin S, Edlund H, MFng is dispensable for mouse pancreas development and function. Mol Cell Biol. 2009 Apr;29(8):2129-38 |
1 | J:307817 Theis A, Singer RA, Garofalo D, Paul A, Narayana A, Sussel L, Groucho co-repressor proteins regulate beta cell development and proliferation by repressing Foxa1 in the developing mouse pancreas. Development. 2021 Mar 24;148(6):dev192401 |
1 | J:235556 Tivodar S, Kalemaki K, Kounoupa Z, Vidaki M, Theodorakis K, Denaxa M, Kessaris N, de Curtis I, Pachnis V, Karagogeos D, Rac-GTPases Regulate Microtubule Stability and Axon Growth of Cortical GABAergic Interneurons. Cereb Cortex. 2015 Sep;25(9):2370-82 |
1 | J:197638 van den Berghe V, Stappers E, Vandesande B, Dimidschstein J, Kroes R, Francis A, Conidi A, Lesage F, Dries R, Cazzola S, Berx G, Kessaris N, Vanderhaeghen P, van Ijcken W, Grosveld FG, Goossens S, Haigh JJ, Fishell G, Goffinet A, Aerts S, Huylebroeck D, Seuntjens E, Directed migration of cortical interneurons depends on the cell-autonomous action of Sip1. Neuron. 2013 Jan 9;77(1):70-82 |
1 | J:193303 Vidaki M, Tivodar S, Doulgeraki K, Tybulewicz V, Kessaris N, Pachnis V, Karagogeos D, Rac1-dependent cell cycle exit of MGE precursors and GABAergic interneuron migration to the cortex. Cereb Cortex. 2012 Mar;22(3):680-92 |
1* | J:41496 Vitale M, Vashishtha A, Linzer E, Powell DJ, Friedman JM, Molecular cloning of the mouse CCK gene: expression in different brain regions and during cortical development. Nucleic Acids Res. 1991 Jan 11;19(1):169-77 |
1 | J:282590 Wei S, Du H, Li Z, Tao G, Xu Z, Song X, Shang Z, Su Z, Chen H, Wen Y, Liu G, You Y, Zhang Z, Yang Z, Transcription factors Sp8 and Sp9 regulate the development of caudal ganglionic eminence-derived cortical interneurons. J Comp Neurol. 2019 Dec 1;527(17):2860-2874 |
1 | J:305176 Wei Y, Han X, Zhao C, PDK1 regulates the survival of the developing cortical interneurons. Mol Brain. 2020 May 4;13(1):65 |
1 | J:201733 Xu Y, Lopes C, Wende H, Guo Z, Cheng L, Birchmeier C, Ma Q, Ontogeny of excitatory spinal neurons processing distinct somatic sensory modalities. J Neurosci. 2013 Sep 11;33(37):14738-48 |
Sstr1 somatostatin receptor 1 (Synonyms: Smstr-1, Smstr1, sst1) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Sstr2 somatostatin receptor 2 (Synonyms: Smstr-2, Smstr2, sst2, SSTR-2) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1 | J:361729 Yang G, He Q, Guo X, Li RY, Lin J, Lang Y, Tao W, Liu W, Lin H, Xing S, Qi Y, Xie Z, Han JJ, Zhou B, Teng Y, Yang X, Identification of the metaphyseal skeletal stem cell building trabecular bone. Sci Adv. 2024 Feb 23;10(8):eadl2238 |
Sstr3 somatostatin receptor 3 (Synonyms: Smstr-3, Smstr3, sst3) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Sstr4 somatostatin receptor 4 (Synonyms: Smstr4, sst4) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Sstr5 somatostatin receptor 5 (Synonyms: Smstr5, sst5) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
St14 suppression of tumorigenicity 14 (colon carcinoma) (Synonyms: Epithin, matriptase, MT-SP1, Prss14, Tmprss14) | |
Results | Reference |
1* | J:117240 Netzel-Arnett S, Currie BM, Szabo R, Lin CY, Chen LM, Chai KX, Antalis TM, Bugge TH, List K, Evidence for a matriptase-prostasin proteolytic cascade regulating terminal epidermal differentiation. J Biol Chem. 2006 Nov 3;281(44):32941-5 |
St18 suppression of tumorigenicity 18 (Synonyms: mKIAA0535, Myt3, Nzf3) | |
Results | Reference |
1 | J:316197 Tennant BR, Chen J, Shih AZ, Luciani DS, Hoffman BG, Myt3 Mediates Laminin-V/Integrin-beta1-Induced Islet-Cell Migration via Tgfbi. Mol Endocrinol. 2015 Sep;29(9):1254-68 |
Stab1 stabilin 1 (Synonyms: mKIAA0246, MS-1) | |
Results | Reference |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Stac src homology three (SH3) and cysteine rich domain | |
Results | Reference |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Stag1 STAG1 cohesin complex component (Synonyms: SA-1, Scc3) | |
Results | Reference |
1 | J:211663 Fukuda T, Fukuda N, Agostinho A, Hernandez-Hernandez A, Kouznetsova A, Hoog C, STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. EMBO J. 2014 Jun 2;33(11):1243-55 |
Stag2 STAG2 cohesin complex component (Synonyms: 9230105L23Rik, B230112I07Rik, nuclear protein SA2, SA-2, SAP2) | |
Results | Reference |
1 | J:211663 Fukuda T, Fukuda N, Agostinho A, Hernandez-Hernandez A, Kouznetsova A, Hoog C, STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. EMBO J. 2014 Jun 2;33(11):1243-55 |
Stag3 STAG3 cohesin complex component (Synonyms: SA-2, stromalin 3) | |
Results | Reference |
1 | J:211663 Fukuda T, Fukuda N, Agostinho A, Hernandez-Hernandez A, Kouznetsova A, Hoog C, STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. EMBO J. 2014 Jun 2;33(11):1243-55 |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
1 | J:153169 Kouznetsova A, Wang H, Bellani M, Camerini-Otero RD, Jessberger R, Hoog C, BRCA1-mediated chromatin silencing is limited to oocytes with a small number of asynapsed chromosomes. J Cell Sci. 2009 Jul 15;122(Pt 14):2446-52 |
Stam2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 (Synonyms: 1200004O12Rik, 5730456G07Rik, Hbp) | |
Results | Reference |
3* | J:180802 Curlin M, Kapuralin K, Muro AF, Baralle FE, Chowdhury K, Gajovic S, Stam2 expression pattern during embryo development. Gene Expr Patterns. 2012 Jan;12(1-2):68-76 |
Star steroidogenic acute regulatory protein (Synonyms: D8Ertd419e) | |
Results | Reference |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:91352 Jeyasuria P, Ikeda Y, Jamin SP, Zhao L, De Rooij DG, Themmen AP, Behringer RR, Parker KL, Cell-specific knockout of steroidogenic factor 1 reveals its essential roles in gonadal function. Mol Endocrinol. 2004 Jul;18(7):1610-9 |
1 | J:307764 Kothandapani A, Larsen MC, Lee J, Jorgensen JS, Jefcoate CR, Distinctive functioning of STARD1 in the fetal Leydig cells compared to adult Leydig and adrenal cells. Impact of Hedgehog signaling via the primary cilium. Mol Cell Endocrinol. 2021 Jul 1;531:111265 |
1 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
1 | J:192626 Miyado M, Nakamura M, Miyado K, Morohashi K, Sano S, Nagata E, Fukami M, Ogata T, Mamld1 deficiency significantly reduces mRNA expression levels of multiple genes expressed in mouse fetal Leydig cells but permits normal genital and reproductive development. Endocrinology. 2012 Dec;153(12):6033-40 |
1* | J:308609 Sararols P, Stevant I, Neirijnck Y, Rebourcet D, Darbey A, Curley MK, Kuhne F, Dermitzakis E, Smith LB, Nef S, Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells. Front Cell Dev Biol. 2021;9:695546 |
1* | J:62908 Venihaki M, Carrigan A, Dikkes P, Majzoub JA, Circadian rise in maternal glucocorticoid prevents pulmonary dysplasia in fetal mice with adrenal insufficiency. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7336-41 |
Stard4 StAR related lipid transfer domain containing 4 (Synonyms: 4632419C16Rik, 9030213J02Rik) | |
Results | Reference |
1* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
Stard7 StAR related lipid transfer domain containing 7 | |
Results | Reference |
1* | J:310743 Lin S, Ikegami M, Moon C, Naren AP, Shannon JM, Lysophosphatidylcholine Acyltransferase 1 (LPCAT1) Specifically Interacts with Phospholipid Transfer Protein StarD10 to Facilitate Surfactant Phospholipid Trafficking in Alveolar Type II Cells. J Biol Chem. 2015 Jul 24;290(30):18559-74 |
Stard10 StAR related lipid transfer domain containing 10 (Synonyms: CGI-52, NY-C0-28, PC-TP2, PCTP2, Pctpl, Sdccag28, TISP-81) | |
Results | Reference |
1* | J:310743 Lin S, Ikegami M, Moon C, Naren AP, Shannon JM, Lysophosphatidylcholine Acyltransferase 1 (LPCAT1) Specifically Interacts with Phospholipid Transfer Protein StarD10 to Facilitate Surfactant Phospholipid Trafficking in Alveolar Type II Cells. J Biol Chem. 2015 Jul 24;290(30):18559-74 |
Stat1 signal transducer and activator of transcription 1 (Synonyms: 2010005J02Rik) | |
Results | Reference |
1 | J:212725 Hong S, Song MR, STAT3 but not STAT1 is required for astrocyte differentiation. PLoS One. 2014;9(1):e86851 |
1 | J:218888 Hong S, Song MR, Signal transducer and activator of transcription-3 maintains the stemness of radial glia at mid-neurogenesis. J Neurosci. 2015 Jan 21;35(3):1011-23 |
1* | J:85765 Nakajima A, Shimizu S, Moriya H, Yamazaki M, Expression of fibroblast growth factor receptor-3 (FGFR3), signal transducer and activator of transcription-1, and cyclin-dependent kinase inhibitor p21 during endochondral ossification: differential role of FGFR3 in skeletal development and fracture repair. Endocrinology. 2003 Oct;144(10):4659-68 |
1 | J:62883 Polizzotto MN, Bartlett PF, Turnley AM, Expression of 'suppressor of cytokine signalling' (SOCS) genes in the developing and adult mouse nervous system. J Comp Neurol. 2000 Jul 24;423(2):348-58 |
1 | J:147287 Retting KN, Song B, Yoon BS, Lyons KM, BMP canonical Smad signaling through Smad1 and Smad5 is required for endochondral bone formation. Development. 2009 Apr;136(7):1093-104 |
1 | J:119669 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM, BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways. Development. 2006 Dec;133(23):4667-78 |
1 | J:238710 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y, Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. PLoS Genet. 2016 Dec;12(12):e1006510 |
1 | J:358835 Zhang J, Gao J, Zeng X, Wang Z, Chen C, Rong C, Li S, Cai L, Wang L, Zhang L, Tian Z, A novel Cdc42-YAP-fibronectin signaling axis regulates ameloblast differentiation during early enamel formation. Biochim Biophys Acta Mol Basis Dis. 2024 Nov 14;1871(2):167570 |
1 | J:82697 Zhang SS, Wei JY, Li C, Barnstable CJ, Fu XY, Expression and activation of STAT proteins during mouse retina development. Exp Eye Res. 2003 Apr;76(4):421-31 |
Stat2 signal transducer and activator of transcription 2 (Synonyms: 1600010G07Rik) | |
Results | Reference |
1 | J:82697 Zhang SS, Wei JY, Li C, Barnstable CJ, Fu XY, Expression and activation of STAT proteins during mouse retina development. Exp Eye Res. 2003 Apr;76(4):421-31 |
Stat3 signal transducer and activator of transcription 3 (Synonyms: 1110034C02Rik, Aprf) | |
Results | Reference |
1 | J:287755 Agarwal M, Sharma A, Kumar P, Kumar A, Bharadwaj A, Saini M, Kardon G, Mathew SJ, Myosin heavy chain-embryonic regulates skeletal muscle differentiation during mammalian development. Development. 2020 Apr 6;147(7):dev184507 |
2 | J:212725 Hong S, Song MR, STAT3 but not STAT1 is required for astrocyte differentiation. PLoS One. 2014;9(1):e86851 |
1 | J:218888 Hong S, Song MR, Signal transducer and activator of transcription-3 maintains the stemness of radial glia at mid-neurogenesis. J Neurosci. 2015 Jan 21;35(3):1011-23 |
1 | J:235955 Laitman BM, Asp L, Mariani JN, Zhang J, Liu J, Sawai S, Chapouly C, Horng S, Kramer EG, Mitiku N, Loo H, Burlant N, Pedre X, Hara Y, Nudelman G, Zaslavsky E, Lee YM, Braun DA, Lu QR, Narla G, Raine CS, Friedman SL, Casaccia P, John GR, The Transcriptional Activator Kruppel-like Factor-6 Is Required for CNS Myelination. PLoS Biol. 2016 May;14(5):e1002467 |
2 | J:237343 Laresgoiti U, Nikolic MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL, Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016 Oct 15;143(20):3686-3699 |
1 | J:163484 Lin MH, Chang KW, Lin SC, Miner JH, Epidermal hyperproliferation in mice lacking fatty acid transport protein 4 (FATP4) involves ectopic EGF receptor and STAT3 signaling. Dev Biol. 2010 Aug 15;344(2):707-19 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1 | J:62883 Polizzotto MN, Bartlett PF, Turnley AM, Expression of 'suppressor of cytokine signalling' (SOCS) genes in the developing and adult mouse nervous system. J Comp Neurol. 2000 Jul 24;423(2):348-58 |
1 | J:205632 Saito A, Kanemoto S, Kawasaki N, Asada R, Iwamoto H, Oki M, Miyagi H, Izumi S, Sanosaka T, Nakashima K, Imaizumi K, Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. Nat Commun. 2012;3:967 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1 | J:110232 Yoshimatsu T, Kawaguchi D, Oishi K, Takeda K, Akira S, Masuyama N, Gotoh Y, Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex. Development. 2006 Jul;133(13):2553-63 |
1 | J:319643 Zhang B, Meng B, Viloria E, Naveau A, Ganss B, Jheon AH, The Role of Epithelial Stat3 in Amelogenesis during Mouse Incisor Renewal. Cells Tissues Organs. 2018;205(2):63-71 |
1 | J:82697 Zhang SS, Wei JY, Li C, Barnstable CJ, Fu XY, Expression and activation of STAT proteins during mouse retina development. Exp Eye Res. 2003 Apr;76(4):421-31 |
Stat4 signal transducer and activator of transcription 4 | |
Results | Reference |
1 | J:82697 Zhang SS, Wei JY, Li C, Barnstable CJ, Fu XY, Expression and activation of STAT proteins during mouse retina development. Exp Eye Res. 2003 Apr;76(4):421-31 |
Stat5a signal transducer and activator of transcription 5A (Synonyms: STAT5) | |
Results | Reference |
2 | J:237343 Laresgoiti U, Nikolic MZ, Rao C, Brady JL, Richardson RV, Batchen EJ, Chapman KE, Rawlins EL, Lung epithelial tip progenitors integrate glucocorticoid- and STAT3-mediated signals to control progeny fate. Development. 2016 Oct 15;143(20):3686-3699 |
1 | J:235014 Legrand JM, Roy E, Ellis JJ, Francois M, Brooks AJ, Khosrotehrani K, STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction. J Invest Dermatol. 2016 Sep;136(9):1781-91 |
1 | J:123223 Markham K, Schuurmans C, Weiss S, STAT5A/B activity is required in the developing forebrain and spinal cord. Mol Cell Neurosci. 2007 Jun;35(2):272-82 |
1* | J:358134 Soma S, Murakami K, Fukuchi Y, Kunimoto H, Nakajima H, O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. Stem Cells. 2024 Jan 13;42(1):55-63 |
1 | J:82697 Zhang SS, Wei JY, Li C, Barnstable CJ, Fu XY, Expression and activation of STAT proteins during mouse retina development. Exp Eye Res. 2003 Apr;76(4):421-31 |
1* | J:356303 Zhao Y, Zheng D, Cvekl A, A comprehensive spatial-temporal transcriptomic analysis of differentiating nascent mouse lens epithelial and fiber cells. Exp Eye Res. 2018 Oct;175:56-72 |
Stat5b signal transducer and activator of transcription 5B | |
Results | Reference |
1 | J:235014 Legrand JM, Roy E, Ellis JJ, Francois M, Brooks AJ, Khosrotehrani K, STAT5 Activation in the Dermal Papilla Is Important for Hair Follicle Growth Phase Induction. J Invest Dermatol. 2016 Sep;136(9):1781-91 |
1 | J:123223 Markham K, Schuurmans C, Weiss S, STAT5A/B activity is required in the developing forebrain and spinal cord. Mol Cell Neurosci. 2007 Jun;35(2):272-82 |
1* | J:358134 Soma S, Murakami K, Fukuchi Y, Kunimoto H, Nakajima H, O-Linked N-Acetylglucosamine Transferase Ensures Survival of Mouse Fetal Liver Hematopoietic Progenitors Partly by Regulating Bcl-xL and Oxidative Phosphorylation. Stem Cells. 2024 Jan 13;42(1):55-63 |
1 | J:82697 Zhang SS, Wei JY, Li C, Barnstable CJ, Fu XY, Expression and activation of STAT proteins during mouse retina development. Exp Eye Res. 2003 Apr;76(4):421-31 |
Stat6 signal transducer and activator of transcription 6 | |
Results | Reference |
1 | J:82697 Zhang SS, Wei JY, Li C, Barnstable CJ, Fu XY, Expression and activation of STAT proteins during mouse retina development. Exp Eye Res. 2003 Apr;76(4):421-31 |
Stau1 staufen double-stranded RNA binding protein 1 (Synonyms: 5830401L18Rik) | |
Results | Reference |
1* | J:104317 Islam S, Montgomery RK, Fialkovich JJ, Grand RJ, Developmental and regional expression and localization of mRNAs encoding proteins involved in RNA translocation. J Histochem Cytochem. 2005 Dec;53(12):1501-9 |
1* | J:160269 Michon F, Tummers M, Kyyronen M, Frilander MJ, Thesleff I, Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol. 2010 Apr 15;340(2):355-68 |
Stau2 staufen double-stranded RNA binding protein 2 | |
Results | Reference |
1* | J:160269 Michon F, Tummers M, Kyyronen M, Frilander MJ, Thesleff I, Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol. 2010 Apr 15;340(2):355-68 |
Stbd1 starch binding domain 1 (Synonyms: D530019K15Rik, D5Ertd593e) | |
Results | Reference |
2* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
Stc1 stanniocalcin 1 | |
Results | Reference |
2* | J:66492 Stasko SE, Wagner GF, Stanniocalcin gene expression during mouse urogenital development: A possible role in mesenchymal-epithelial signalling. Dev Dyn. 2001 Jan;220(1):49-59 |
2* | J:72537 Stasko SE, Wagner GF, Possible roles for stanniocalcin during early skeletal patterning and joint formation in the mouse. J Endocrinol. 2001 Nov;171(2):237-48 |
3 | J:75561 Yoshiko Y, Aubin JE, Maeda N, Stanniocalcin 1 (STC1) protein and mRNA are developmentally regulated during embryonic mouse osteogenesis: the potential of stc1 as an autocrine/paracrine factor for osteoblast development and bone formation. J Histochem Cytochem. 2002 Apr;50(4):483-92 |
Stim1 stromal interaction molecule 1 (Synonyms: SIM) | |
Results | Reference |
2* | J:145505 Stiber J, Hawkins A, Zhang ZS, Wang S, Burch J, Graham V, Ward CC, Seth M, Finch E, Malouf N, Williams RS, Eu JP, Rosenberg P, STIM1 signalling controls store-operated calcium entry required for development and contractile function in skeletal muscle. Nat Cell Biol. 2008 Jun;10(6):688-97 |
Stk3 serine/threonine kinase 3 (Synonyms: 0610042I06Rik, mess1, MST, Mst2, Ste20) | |
Results | Reference |
1 | J:192856 George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE, Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol. 2012 Dec;32(24):5116-28 |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
Stk4 serine/threonine kinase 4 (Synonyms: Kas-2, Mst1, sterile 20-like kinase 1, Ysk3) | |
Results | Reference |
1 | J:192856 George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE, Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol. 2012 Dec;32(24):5116-28 |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
1 | J:346063 Rehmani T, Dias AP, Kamal M, Salih M, Tuana BS, Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway. Int J Mol Sci. 2024 Mar 1;25(5) |
Stk10 serine/threonine kinase 10 (Synonyms: Gek1, Lok) | |
Results | Reference |
1* | J:37035 Yanagisawa M, Mukouyama Y, Watanabe T, Obinata M, Matsui Y, A novel serine/threonine kinase gene, Gek1, is expressed in meiotic testicular germ cells and primordial germ cells. Mol Reprod Dev. 1996 Dec;45(4):411-20 |
Stk11 serine/threonine kinase 11 (Synonyms: Lkb1, Par-4) | |
Results | Reference |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1 | J:134078 Hezel AF, Gurumurthy S, Granot Z, Swisa A, Chu GC, Bailey G, Dor Y, Bardeesy N, Depinho RA, Pancreatic LKB1 deletion leads to acinar polarity defects and cystic neoplasms. Mol Cell Biol. 2008 Apr;28(7):2414-25 |
2 | J:207603 Veleva-Rotse BO, Smart JL, Baas AF, Edmonds B, Zhao ZM, Brown A, Klug LR, Hansen K, Reilly G, Gardner AP, Subbiah K, Gaucher EA, Clevers H, Barnes AP, STRAD pseudokinases regulate axogenesis and LKB1 stability. Neural Dev. 2014;9:5 |
Stk36 serine/threonine kinase 36 (Synonyms: 1700112N14Rik, Fused) | |
Results | Reference |
1 | J:116391 Merchant M, Evangelista M, Luoh SM, Frantz GD, Chalasani S, Carano RA, van Hoy M, Ramirez J, Ogasawara AK, McFarland LM, Filvaroff EH, French DM, de Sauvage FJ, Loss of the serine/threonine kinase fused results in postnatal growth defects and lethality due to progressive hydrocephalus. Mol Cell Biol. 2005 Aug;25(16):7054-68 |
Stk40 serine/threonine kinase 40 (Synonyms: 2310004N11Rik) | |
Results | Reference |
1* | J:238480 He K, Hu J, Yu H, Wang L, Tang F, Gu J, Ge L, Wang H, Li S, Hu P, Jin Y, Serine/Threonine Kinase 40 (Stk40) Functions as a Novel Regulator of Skeletal Muscle Differentiation. J Biol Chem. 2017 Jan 06;292(1):351-360 |
Stmn1 stathmin 1 (Synonyms: 19K, Lag, Lap18, leukemia associated phosphoprotein p18, metablastin, oncoprotein18, op18, p18, p19, pig, PP17, PP18, PR22, prosolin, SMN) | |
Results | Reference |
1* | J:74091 Camoletto P, Colesanti A, Ozon S, Sobel A, Fasolo A, Expression of stathmin and SCG10 proteins in the olfactory neurogenesis during development and after lesion in the adulthood. Brain Res Bull. 2001 Jan 1;54(1):19-28 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Stmn2 stathmin-like 2 (Synonyms: SCG10, Scgn10) | |
Results | Reference |
1 | J:181188 Aoki H, Hara A, Era T, Kunisada T, Yamada Y, Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development. 2012 Feb;139(4):667-77 |
1 | J:315092 Hu ZL, Zhang X, Shi M, Tian ZW, Huang Y, Chen JY, Ding YQ, Delayed but not loss of gliogenesis in Rbpj-deficient trigeminal ganglion. Int J Clin Exp Pathol. 2013;6(7):1261-71 |
1 | J:142008 Huang M, Huang T, Xiang Y, Xie Z, Chen Y, Yan R, Xu J, Cheng L, Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons. Dev Biol. 2008 Jul 2;322(2):394-405 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
1 | J:173638 Schmidt M, Huber L, Majdazari A, Schutz G, Williams T, Rohrer H, The transcription factors AP-2beta and AP-2alpha are required for survival of sympathetic progenitors and differentiated sympathetic neurons. Dev Biol. 2011 Jul 1;355(1):89-100 |
1 | J:201069 Stubbusch J, Narasimhan P, Huber K, Unsicker K, Rohrer H, Ernsberger U, Synaptic protein and pan-neuronal gene expression and their regulation by Dicer-dependent mechanisms differ between neurons and neuroendocrine cells. Neural Dev. 2013 Aug 20;8(1):16 |
Stmp1 short transmembrane mitochondrial protein 1 (Synonyms: 1810058I24Rik) | |
Results | Reference |
1* | J:331690 Zheng X, Guo Y, Zhang R, Chen H, Liu S, Qiu S, Xiang M, The mitochondrial micropeptide Stmp1 promotes retinal cell differentiation. Biochem Biophys Res Commun. 2022 Dec 25;636(Pt 2):79-86 |
Stra6 stimulated by retinoic acid gene 6 | |
Results | Reference |
1* | J:40904 Bouillet P, Sapin V, Chazaud C, Messaddeq N, Decimo D, Dolle P , Chambon P, Developmental expression pattern of Stra6, a retinoic acid-responsive gene encoding a new type of membrane protein. Mech Dev. 1997 May;63(2):173-86 |
1* | J:35169 Chazaud C, Bouillet P, Oulad-Abdelghani M, Dolle P, Restricted expression of a novel retinoic acid responsive gene during limb bud dorsoventral patterning and endochondral ossification. Dev Genet. 1996;19(1):66-73 |
Stra8 stimulated by retinoic acid gene 8 | |
Results | Reference |
2* | J:305426 Du G, Oatley MJ, Law NC, Robbins C, Wu X, Oatley JM, Proper timing of a quiescence period in precursor prospermatogonia is required for stem cell pool establishment in the male germline. Development. 2021 May 1;148(9):dev194571 |
1* | J:290712 Ishiguro KI, Matsuura K, Tani N, Takeda N, Usuki S, Yamane M, Sugimoto M, Fujimura S, Hosokawa M, Chuma S, Ko MSH, Araki K, Niwa H, MEIOSIN Directs the Switch from Mitosis to Meiosis in Mammalian Germ Cells. Dev Cell. 2020 Feb 24;52(4):429-445.e10 |
1 | J:154048 Li H, MacLean G, Cameron D, Clagett-Dame M, Petkovich M, Cyp26b1 expression in murine Sertoli cells is required to maintain male germ cells in an undifferentiated state during embryogenesis. PLoS One. 2009;4(10):e7501 |
1* | J:86170 Menke DB, Koubova J, Page DC, Sexual differentiation of germ cells in XX mouse gonads occurs in an anterior-to-posterior wave. Dev Biol. 2003 Oct 15;262(2):303-12 |
1 | J:158526 Naillat F, Prunskaite-Hyyrylainen R, Pietila I, Sormunen R, Jokela T, Shan J, Vainio SJ, Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development. Hum Mol Genet. 2010 Apr 15;19(8):1539-50 |
1 | J:36069 Oulad-Abdelghani M, Bouillet P, Decimo D, Gansmuller A, Heyberger S, Dolle P, Bronner S, Lutz Y, Chambon P, Characterization of a premeiotic germ cell-specific cytoplasmic protein encoded by Stra8, a novel retinoic acid-responsive gene. J Cell Biol. 1996 Oct;135(2):469-77 |
1* | J:241573 Pui HP, Saga Y, Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling. Mech Dev. 2017 Apr;144(Pt B):125-139 |
1 | J:307649 Satirapod C, Wang N, MacDonald JA, Sun M, Woods DC, Tilly JL, Estrogen regulation of germline stem cell differentiation as a mechanism contributing to female reproductive aging. Aging (Albany NY). 2020 Apr 17;12(8):7313-7333 |
2 | J:362758 Zhang L, Li Y, Hu Y, Chen M, Cen C, Chen M, Lin L, Zhou J, Wang M, Cui X, Tang F, Gao F, Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression. FASEB J. 2022 Feb;36(2):e22131 |
Strada STE20-related kinase adaptor alpha (Synonyms: 2610019A05Rik, 6030402H20Rik) | |
Results | Reference |
2 | J:207603 Veleva-Rotse BO, Smart JL, Baas AF, Edmonds B, Zhao ZM, Brown A, Klug LR, Hansen K, Reilly G, Gardner AP, Subbiah K, Gaucher EA, Clevers H, Barnes AP, STRAD pseudokinases regulate axogenesis and LKB1 stability. Neural Dev. 2014;9:5 |
Stradb STE20-related kinase adaptor beta (Synonyms: Als2cr2, D1Ucla2, PRO1038) | |
Results | Reference |
1 | J:207603 Veleva-Rotse BO, Smart JL, Baas AF, Edmonds B, Zhao ZM, Brown A, Klug LR, Hansen K, Reilly G, Gardner AP, Subbiah K, Gaucher EA, Clevers H, Barnes AP, STRAD pseudokinases regulate axogenesis and LKB1 stability. Neural Dev. 2014;9:5 |
Strn striatin, calmodulin binding protein | |
Results | Reference |
1 | J:346063 Rehmani T, Dias AP, Kamal M, Salih M, Tuana BS, Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway. Int J Mol Sci. 2024 Mar 1;25(5) |
Strn3 striatin, calmodulin binding protein 3 (Synonyms: SG2NA) | |
Results | Reference |
1 | J:346063 Rehmani T, Dias AP, Kamal M, Salih M, Tuana BS, Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway. Int J Mol Sci. 2024 Mar 1;25(5) |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Sts steroid sulfatase (Synonyms: ArsC) | |
Results | Reference |
1* | J:43858 Compagnone NA, Salido E, Shapiro LJ, Mellon SH, Expression of steroid sulfatase during embryogenesis. Endocrinology. 1997 Nov;138(11):4768-73 |
Stub1 STIP1 homology and U-Box containing protein 1 (Synonyms: 0610033N24Rik, 2210017D18Rik, 2310040B03Rik, CHIP) | |
Results | Reference |
4* | J:336094 Zheng H, Zhang X, Fu J, Xue Y, Chen Z, Yang G, Chen Y, Chen D, Yuan G, CHIP inhibits odontoblast differentiation through promoting DLX3 polyubiquitylation and degradation. Development. 2023 May 15;150(10):dev200848 |
Stum mechanosensory transduction mediator (Synonyms: 6330403A02Rik) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Stx1a syntaxin 1A (brain) (Synonyms: HPC-1) | |
Results | Reference |
1* | J:181601 Bassett EA, Korol A, Deschamps PA, Buettner R, Wallace VA, Williams T, West-Mays JA, Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29 |
1* | J:56117 Noakes PG, Chin D, Kim SS, Liang S, Phillips WD, Expression and localisation of dynamin and syntaxin during neural development and neuromuscular synapse formation. J Comp Neurol. 1999 Aug 9;410(4):531-40 |
Stx5a syntaxin 5A (Synonyms: 0610031F24Rik, D19Ertd627e, syntaxin 5) | |
Results | Reference |
1 | J:253982 Norlin S, Parekh V, Edlund H, The ATPase activity of Asna1/TRC40 is required for pancreatic progenitor cell survival. Development. 2018 Jan 3;145(1):dev154468 |
Stxbp1 syntaxin binding protein 1 (Synonyms: Munc18-1, Munc-18a, nsec1, N-sec1, Rb-sec1, Sxtbp1, Unc18h) | |
Results | Reference |
1 | J:119559 Bouwman J, Spijker S, Schut D, Wachtler B, Ylstra B, Smit AB, Verhage M, Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse. J Neurochem. 2006 Oct;99(1):84-96 |
Stxbp2 syntaxin binding protein 2 (Synonyms: C79054, Munc-18-2, Munc-18b, Munc18b, muSec1, Sxtp2) | |
Results | Reference |
1 | J:59870 Han SH, Morgan JI, Comparison of munc-18 and cdk5 expression in the nervous system during mouse embryogenesis. Neuroscience. 1999;94(3):955-64 |
Stxbp5 syntaxin binding protein 5 (tomosyn) (Synonyms: 0710001E20Rik, 4930565N16Rik, LGL3, mKIAA1006, tomosyn 1) | |
Results | Reference |
1 | J:96244 Groffen AJ, Jacobsen L, Schut D, Verhage M, Two distinct genes drive expression of seven tomosyn isoforms in the mammalian brain, sharing a conserved structure with a unique variable domain. J Neurochem. 2005 Feb;92(3):554-68 |
Stxbp5l syntaxin binding protein 5-like (Synonyms: A830015P08Rik, insulin level locus 1, LLGL4, T2dm1, t2md1, tomosyn-2) | |
Results | Reference |
1 | J:96244 Groffen AJ, Jacobsen L, Schut D, Verhage M, Two distinct genes drive expression of seven tomosyn isoforms in the mammalian brain, sharing a conserved structure with a unique variable domain. J Neurochem. 2005 Feb;92(3):554-68 |
Stxbp6 syntaxin binding protein 6 (amisyn) (Synonyms: MGC:30948) | |
Results | Reference |
1 | J:208050 Huang TN, Chuang HC, Chou WH, Chen CY, Wang HF, Chou SJ, Hsueh YP, Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality. Nat Neurosci. 2014 Feb;17(2):240-7 |
Suclg2 succinate-Coenzyme A ligase, GDP-forming, beta subunit (Synonyms: D6Wsu120e) | |
Results | Reference |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
Sufu SUFU negative regulator of hedgehog signaling (Synonyms: 2810026F04Rik, b2b273Clo, Su(Fu)) | |
Results | Reference |
2* | J:58014 Ding Q, Fukami Si, Meng X, Nishizaki Y, Zhang X, Sasaki H, Dlugosz A, Nakafuku M, Hui Cc, Mouse suppressor of fused is a negative regulator of sonic hedgehog signaling and alters the subcellular distribution of Gli1. Curr Biol. 1999 Oct 7;9(19):1119-22 |
2 | J:175769 Hsu SH, Zhang X, Yu C, Li ZJ, Wunder JS, Hui CC, Alman BA, Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu. Development. 2011 Sep;138(17):3791-801 |
1* | J:113421 Szczepny A, Hime GR, Loveland KL, Expression of hedgehog signalling components in adult mouse testis. Dev Dyn. 2006 Nov;235(11):3063-70 |
1 | J:282462 Yabut OR, Ng HX, Fernandez G, Yoon K, Kuhn J, Pleasure SJ, Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors. J Dev Biol. 2016 Dec;4(4) |
Sulf1 sulfatase 1 | |
Results | Reference |
2 | J:124898 Ai X, Kitazawa T, Do AT, Kusche-Gullberg M, Labosky PA, Emerson CP Jr, SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation. Development. 2007 Sep;134(18):3327-38 |
1* | J:191132 Buresh-Stiemke RA, Malinowski RL, Keil KP, Vezina CM, Oosterhof A, Van Kuppevelt TH, Marker PC, Distinct expression patterns of Sulf1 and Hs6st1 spatially regulate heparan sulfate sulfation during prostate development. Dev Dyn. 2012 Dec;241(12):2005-13 |
1* | J:184289 Hayano S, Kurosaka H, Yanagita T, Kalus I, Milz F, Ishihara Y, Islam MN, Kawanabe N, Saito M, Kamioka H, Adachi T, Dierks T, Yamashiro T, Roles of heparan sulfate sulfation in dentinogenesis. J Biol Chem. 2012 Apr 6;287(15):12217-29 |
1 | J:293401 Phua YL, Chen KH, Hemker SL, Marrone AK, Bodnar AJ, Liu X, Clugston A, Kostka D, Butterworth MB, Ho J, Loss of miR-17~92 results in dysregulation of Cftr in nephron progenitors. Am J Physiol Renal Physiol. 2019 May 1;316(5):F993-F1005 |
1* | J:130163 Ratzka A, Kalus I, Moser M, Dierks T, Mundlos S, Vortkamp A, Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development. Dev Dyn. 2008 Feb;237(2):339-53 |
1* | J:160587 Ratzka A, Mundlos S, Vortkamp A, Expression patterns of sulfatase genes in the developing mouse embryo. Dev Dyn. 2010 Jun;239(6):1779-88 |
Sulf2 sulfatase 2 (Synonyms: 2010004N24Rik, mKIAA1247) | |
Results | Reference |
1* | J:184289 Hayano S, Kurosaka H, Yanagita T, Kalus I, Milz F, Ishihara Y, Islam MN, Kawanabe N, Saito M, Kamioka H, Adachi T, Dierks T, Yamashiro T, Roles of heparan sulfate sulfation in dentinogenesis. J Biol Chem. 2012 Apr 6;287(15):12217-29 |
1* | J:130163 Ratzka A, Kalus I, Moser M, Dierks T, Mundlos S, Vortkamp A, Redundant function of the heparan sulfate 6-O-endosulfatases Sulf1 and Sulf2 during skeletal development. Dev Dyn. 2008 Feb;237(2):339-53 |
1* | J:160587 Ratzka A, Mundlos S, Vortkamp A, Expression patterns of sulfatase genes in the developing mouse embryo. Dev Dyn. 2010 Jun;239(6):1779-88 |
Sult1e1 sulfotransferase family 1E, member 1 (Synonyms: EST, Ste) | |
Results | Reference |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1* | J:308609 Sararols P, Stevant I, Neirijnck Y, Rebourcet D, Darbey A, Curley MK, Kuhne F, Dermitzakis E, Smith LB, Nef S, Specific Transcriptomic Signatures and Dual Regulation of Steroidogenesis Between Fetal and Adult Mouse Leydig Cells. Front Cell Dev Biol. 2021;9:695546 |
2* | J:96050 Tong MH, Jiang H, Liu P, Lawson JA, Brass LF, Song WC, Spontaneous fetal loss caused by placental thrombosis in estrogen sulfotransferase-deficient mice. Nat Med. 2005 Feb;11(2):153-9 |
Sumf1 sulfatase modifying factor 1 | |
Results | Reference |
2* | J:143455 Settembre C, Arteaga-Solis E, McKee MD, de Pablo R, Al Awqati Q, Ballabio A, Karsenty G, Proteoglycan desulfation determines the efficiency of chondrocyte autophagy and the extent of FGF signaling during endochondral ossification. Genes Dev. 2008 Oct 1;22(19):2645-50 |
Sumo1 small ubiquitin-like modifier 1 (Synonyms: PIC1, SENTRIN, Smt3C, Ubl1) | |
Results | Reference |
1* | J:315590 Fujiwara K, Hasegawa K, Oka M, Yoneda Y, Yoshikawa K, Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system. Genes Cells. 2016 Nov;21(11):1176-1194 |
2* | J:208871 Gong L, Ji WK, Hu XH, Hu WF, Tang XC, Huang ZX, Li L, Liu M, Xiang SH, Wu E, Woodward Z, Liu YZ, Nguyen QD, Li DW, Sumoylation differentially regulates Sp1 to control cell differentiation. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5574-9 |
1 | J:183651 Kim EY, Chen L, Ma Y, Yu W, Chang J, Moskowitz IP, Wang J, Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J Mol Cell Cardiol. 2012 Mar;52(3):638-49 |
1* | J:356303 Zhao Y, Zheng D, Cvekl A, A comprehensive spatial-temporal transcriptomic analysis of differentiating nascent mouse lens epithelial and fiber cells. Exp Eye Res. 2018 Oct;175:56-72 |
Sumo2 small ubiquitin-like modifier 2 (Synonyms: Smt3b, Smt3h2) | |
Results | Reference |
1* | J:315590 Fujiwara K, Hasegawa K, Oka M, Yoneda Y, Yoshikawa K, Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system. Genes Cells. 2016 Nov;21(11):1176-1194 |
2* | J:208871 Gong L, Ji WK, Hu XH, Hu WF, Tang XC, Huang ZX, Li L, Liu M, Xiang SH, Wu E, Woodward Z, Liu YZ, Nguyen QD, Li DW, Sumoylation differentially regulates Sp1 to control cell differentiation. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5574-9 |
1 | J:183651 Kim EY, Chen L, Ma Y, Yu W, Chang J, Moskowitz IP, Wang J, Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J Mol Cell Cardiol. 2012 Mar;52(3):638-49 |
Sumo3 small ubiquitin-like modifier 3 (Synonyms: 2810014B19Rik, D10Ertd345e, SMT3A, Smt3h1) | |
Results | Reference |
1* | J:315590 Fujiwara K, Hasegawa K, Oka M, Yoneda Y, Yoshikawa K, Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system. Genes Cells. 2016 Nov;21(11):1176-1194 |
2* | J:208871 Gong L, Ji WK, Hu XH, Hu WF, Tang XC, Huang ZX, Li L, Liu M, Xiang SH, Wu E, Woodward Z, Liu YZ, Nguyen QD, Li DW, Sumoylation differentially regulates Sp1 to control cell differentiation. Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5574-9 |
1 | J:183651 Kim EY, Chen L, Ma Y, Yu W, Chang J, Moskowitz IP, Wang J, Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction. J Mol Cell Cardiol. 2012 Mar;52(3):638-49 |
1* | J:356303 Zhao Y, Zheng D, Cvekl A, A comprehensive spatial-temporal transcriptomic analysis of differentiating nascent mouse lens epithelial and fiber cells. Exp Eye Res. 2018 Oct;175:56-72 |
Sun1 Sad1 and UNC84 domain containing 1 (Synonyms: 4632417G13Rik, 5730434D03Rik, mKIAA0810, Unc84a) | |
Results | Reference |
2 | J:252201 Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A, p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct;137(10):2157-2167 |
1 | J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088 |
Sun2 Sad1 and UNC84 domain containing 2 (Synonyms: B230369L08Rik, Unc84b) | |
Results | Reference |
1 | J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088 |
Supv3l1 suppressor of var1, 3-like 1 (S. cerevisiae) (Synonyms: 6330443E10Rik) | |
Results | Reference |
1* | J:163582 Paul E, Kielbasinski M, Sedivy JM, Murga-Zamalloa C, Khanna H, Klysik JE, Widespread expression of the Supv3L1 mitochondrial RNA helicase in the mouse. Transgenic Res. 2010 Aug;19(4):691-701 |
Susd4 sushi domain containing 4 (Synonyms: E430021N18Rik) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Suv39h1 suppressor of variegation 3-9 1 (Synonyms: DXHXS7466e, KMT1A, mIS6, Suv39h histone methyltransferase) | |
Results | Reference |
1 | J:173973 Benlhabib H, Mendelson CR, Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia. Mol Cell Biol. 2011 May;31(10):1949-58 |
2* | J:194983 Ideno H, Shimada A, Imaizumi K, Kimura H, Abe M, Nakashima K, Nifuji A, Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development. Gene Expr Patterns. 2013 Mar-Apr;13(3-4):84-90 |
2 | J:315014 Zhou C, Chen D, Ren J, Huang D, Li R, Luo H, Guan C, Cao Y, Wang W, FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex. J Cell Mol Med. 2021 Mar;25(6):3051-3062 |
Suv39h2 suppressor of variegation 3-9 2 (Synonyms: 4930507K23Rik, D2Ertd544e, KMT1B, Suv39h histone methyltransferase) | |
Results | Reference |
1 | J:173973 Benlhabib H, Mendelson CR, Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia. Mol Cell Biol. 2011 May;31(10):1949-58 |
2* | J:194983 Ideno H, Shimada A, Imaizumi K, Kimura H, Abe M, Nakashima K, Nifuji A, Predominant expression of H3K9 methyltransferases in prehypertrophic and hypertrophic chondrocytes during mouse growth plate cartilage development. Gene Expr Patterns. 2013 Mar-Apr;13(3-4):84-90 |
Suz12 SUZ12 polycomb repressive complex 2 subunit (Synonyms: 2610028O16Rik, D11Ertd530e, mKIAA0160) | |
Results | Reference |
1 | J:316527 Chen HH, Welling M, Bloch DB, Munoz J, Mientjes E, Chen X, Tramp C, Wu J, Yabuuchi A, Chou YF, Buecker C, Krainer A, Willemsen R, Heck AJ, Geijsen N, DAZL limits pluripotency, differentiation, and apoptosis in developing primordial germ cells. Stem Cell Reports. 2014 Nov 11;3(5):892-904 |
1* | J:150128 Miro X, Zhou X, Boretius S, Michaelis T, Kubisch C, Alvarez-Bolado G, Gruss P, Haploinsufficiency of the murine polycomb gene Suz12 results in diverse malformations of the brain and neural tube. Dis Model Mech. 2009 Jul-Aug;2(7-8):412-8 |
Sv2a synaptic vesicle glycoprotein 2a | |
Results | Reference |
1 | J:336102 Eenjes E, Benthem F, Boerema-de Munck A, Buscop-van Kempen M, Tibboel D, Rottier RJ, Distinct roles for SOX2 and SOX21 in differentiation, distribution and maturation of pulmonary neuroendocrine cells. Cell Mol Life Sci. 2023 Mar 3;80(3):79 |
Svep1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 (Synonyms: 1110021D17Rik, 4833413O10Rik, D430029O09Rik, Polydom) | |
Results | Reference |
1* | J:315946 Sato-Nishiuchi R, Nakano I, Ozawa A, Sato Y, Takeichi M, Kiyozumi D, Yamazaki K, Yasunaga T, Futaki S, Sekiguchi K, Polydom/SVEP1 is a ligand for integrin alpha9beta1. J Biol Chem. 2012 Jul 20;287(30):25615-30 |
Svet1 subventricular expressed transcript 1 | |
Results | Reference |
1 | J:150768 Okado H, Ohtaka-Maruyama C, Sugitani Y, Fukuda Y, Ishida R, Hirai S, Miwa A, Takahashi A, Aoki K, Mochida K, Suzuki O, Honda T, Nakajima K, Ogawa M, Terashima T, Matsuda J, Kawano H, Kasai M, The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Dev Biol. 2009 Jul 15;331(2):140-51 |
1 | J:109774 Roy K, Kuznicki K, Wu Q, Sun Z, Bock D, Schutz G, Vranich N, Monaghan AP, The Tlx gene regulates the timing of neurogenesis in the cortex. J Neurosci. 2004 Sep 22;24(38):8333-45 |
2 | J:141783 Sasaki S, Tabata H, Tachikawa K, Nakajima K, The cortical subventricular zone-specific molecule Svet1 is part of the nuclear RNA coded by the putative Netrin receptor gene Unc5d and is expressed in multipolar migrating cells. Mol Cell Neurosci. 2008 Aug;38(4):474-83 |
1* | J:143543 Vogel T, Gruss P, Expression of Leukaemia associated transcription factor Af9/Mllt3 in the cerebral cortex of the mouse. Gene Expr Patterns. 2009 Feb;9(2):83-93 |
Svopl SV2 related protein homolog (rat)-like (Synonyms: 9430071P14Rik) | |
Results | Reference |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
Syce1 synaptonemal complex central element protein 1 (Synonyms: 4933406J07Rik) | |
Results | Reference |
1 | J:325094 Guan Y, Lin H, Leu NA, Ruthel G, Fuchs SY, Busino L, Luo M, Wang PJ, SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination. Nucleic Acids Res. 2022 May 20;50(9):5129-5144 |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
Syce2 synaptonemal complex central element protein 2 (Synonyms: 1700013H19Rik) | |
Results | Reference |
1 | J:173089 Daniel K, Lange J, Hached K, Fu J, Anastassiadis K, Roig I, Cooke HJ, Stewart AF, Wassmann K, Jasin M, Keeney S, Toth A, Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1. Nat Cell Biol. 2011 May;13(5):599-610 |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
Syce3 synaptonemal complex central element protein 3 (Synonyms: 1700007E06Rik) | |
Results | Reference |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
1 | J:172714 Schramm S, Fraune J, Naumann R, Hernandez-Hernandez A, Hoog C, Cooke HJ, Alsheimer M, Benavente R, A novel mouse synaptonemal complex protein is essential for loading of central element proteins, recombination, and fertility. PLoS Genet. 2011 May;7(5):e1002088 |
Sycp1 synaptonemal complex protein 1 (Synonyms: SCP1) | |
Results | Reference |
2* | J:63364 Di Carlo AD, Travia G, De Felici M, The meiotic specific synaptonemal complex protein SCP3 is expressed by female and male primordial germ cells of the mouse embryo. Int J Dev Biol. 2000 Feb;44(2):241-4 |
1 | J:211663 Fukuda T, Fukuda N, Agostinho A, Hernandez-Hernandez A, Kouznetsova A, Hoog C, STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. EMBO J. 2014 Jun 2;33(11):1243-55 |
1 | J:325094 Guan Y, Lin H, Leu NA, Ruthel G, Fuchs SY, Busino L, Luo M, Wang PJ, SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination. Nucleic Acids Res. 2022 May 20;50(9):5129-5144 |
1 | J:326085 Huang TC, Wang YF, Vazquez-Ferrer E, Theofel I, Requena CE, Hanna CW, Kelsey G, Hajkova P, Sex-specific chromatin remodelling safeguards transcription in germ cells. Nature. 2021 Dec;600(7890):737-742 |
1 | J:213984 Kogo H, Tsutsumi M, Ohye T, Inagaki H, Abe T, Kurahashi H, HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes. Genes Cells. 2012 Jun;17(6):439-54 |
1* | J:87821 Olesen C, Moller M, Byskov AG, Tesmin transcription is regulated differently during male and female meiosis. Mol Reprod Dev. 2004 Jan;67(1):116-26 |
1 | J:342011 Shimada R, Kato Y, Takeda N, Fujimura S, Yasunaga KI, Usuki S, Niwa H, Araki K, Ishiguro KI, STRA8-RB interaction is required for timely entry of meiosis in mouse female germ cells. Nat Commun. 2023 Oct 25;14(1):6443 |
1 | J:313675 Soygur B, Jaszczak RG, Fries A, Nguyen DH, Malki S, Hu G, Demir N, Arora R, Laird DJ, Intercellular bridges coordinate the transition from pluripotency to meiosis in mouse fetal oocytes. Sci Adv. 2021 Apr;7(15) |
1 | J:83946 Tay J, Hodgman R, Sarkissian M, Richter JD, Regulated CPEB phosphorylation during meiotic progression suggests a mechanism for temporal control of maternal mRNA translation. Genes Dev. 2003 Jun 15;17(12):1457-62 |
2 | J:102097 Tay J, Richter JD, Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice. Dev Cell. 2001 Aug;1(2):201-13 |
1 | J:194101 Yamaguchi S, Hong K, Liu R, Shen L, Inoue A, Diep D, Zhang K, Zhang Y, Tet1 controls meiosis by regulating meiotic gene expression. Nature. 2012 Dec 20;492(7429):443-7 |
1* | J:90277 Yao HH, Matzuk MM, Jorgez CJ, Menke DB, Page DC, Swain A, Capel B, Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis. Dev Dyn. 2004 Jun;230(2):210-5 |
Sycp2 synaptonemal complex protein 2 (Synonyms: 3830402K23Rik, 4930518F03Rik) | |
Results | Reference |
1 | J:211663 Fukuda T, Fukuda N, Agostinho A, Hernandez-Hernandez A, Kouznetsova A, Hoog C, STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. EMBO J. 2014 Jun 2;33(11):1243-55 |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
1 | J:213575 Malki S, van der Heijden GW, O'Donnell KA, Martin SL, Bortvin A, A role for retrotransposon LINE-1 in fetal oocyte attrition in mice. Dev Cell. 2014 Jun 9;29(5):521-33 |
1 | J:203746 Shin YH, McGuire MM, Rajkovic A, Mouse HORMAD1 is a meiosis i checkpoint protein that modulates DNA double- strand break repair during female meiosis. Biol Reprod. 2013 Aug;89(2):29 |
Sycp3 synaptonemal complex protein 3 (Synonyms: Cor1, Scp3) | |
Results | Reference |
1 | J:167041 Cook MS, Munger SC, Nadeau JH, Capel B, Regulation of male germ cell cycle arrest and differentiation by DND1 is modulated by genetic background. Development. 2011 Jan;138(1):23-32 |
1 | J:173089 Daniel K, Lange J, Hached K, Fu J, Anastassiadis K, Roig I, Cooke HJ, Stewart AF, Wassmann K, Jasin M, Keeney S, Toth A, Meiotic homologue alignment and its quality surveillance are controlled by mouse HORMAD1. Nat Cell Biol. 2011 May;13(5):599-610 |
1 | J:242462 Daniel K, Trankner D, Wojtasz L, Shibuya H, Watanabe Y, Alsheimer M, Toth A, Mouse CCDC79 (TERB1) is a meiosis-specific telomere associated protein. BMC Cell Biol. 2014 May 22;15:17 |
1* | J:63364 Di Carlo AD, Travia G, De Felici M, The meiotic specific synaptonemal complex protein SCP3 is expressed by female and male primordial germ cells of the mouse embryo. Int J Dev Biol. 2000 Feb;44(2):241-4 |
1 | J:211663 Fukuda T, Fukuda N, Agostinho A, Hernandez-Hernandez A, Kouznetsova A, Hoog C, STAG3-mediated stabilization of REC8 cohesin complexes promotes chromosome synapsis during meiosis. EMBO J. 2014 Jun 2;33(11):1243-55 |
1 | J:325094 Guan Y, Lin H, Leu NA, Ruthel G, Fuchs SY, Busino L, Luo M, Wang PJ, SCF ubiquitin E3 ligase regulates DNA double-strand breaks in early meiotic recombination. Nucleic Acids Res. 2022 May 20;50(9):5129-5144 |
1 | J:292630 Holton RA, Harris AM, Mukerji B, Singh T, Dia F, Berkowitz KM, CHTF18 ensures the quantity and quality of the ovarian reserve. Biol Reprod. 2020 Jun 23;103(1):24-35 |
1 | J:307864 Horisawa-Takada Y, Kodera C, Takemoto K, Sakashita A, Horisawa K, Maeda R, Shimada R, Usuki S, Fujimura S, Tani N, Matsuura K, Akiyama T, Suzuki A, Niwa H, Tachibana M, Ohba T, Katabuchi H, Namekawa SH, Araki K, Ishiguro KI, Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis. Nat Commun. 2021 Jun 1;12(1):3184 |
1 | J:326085 Huang TC, Wang YF, Vazquez-Ferrer E, Theofel I, Requena CE, Hanna CW, Kelsey G, Hajkova P, Sex-specific chromatin remodelling safeguards transcription in germ cells. Nature. 2021 Dec;600(7890):737-742 |
1 | J:361445 Ito M, Yun Y, Kulkarni DS, Lee S, Sandhu S, Nunez B, Hu L, Lee K, Lim N, Hirota RM, Prendergast R, Huang C, Huang I, Hunter N, Distinct and interdependent functions of three RING proteins regulate recombination during mammalian meiosis. Proc Natl Acad Sci U S A. 2025 Jan 14;122(2):e2412961121 |
1 | J:188056 Jameson SA, Lin YT, Capel B, Testis development requires the repression of Wnt4 by Fgf signaling. Dev Biol. 2012 Oct 1;370(1):24-32 |
1 | J:213984 Kogo H, Tsutsumi M, Ohye T, Inagaki H, Abe T, Kurahashi H, HORMAD1-dependent checkpoint/surveillance mechanism eliminates asynaptic oocytes. Genes Cells. 2012 Jun;17(6):439-54 |
1 | J:154048 Li H, MacLean G, Cameron D, Clagett-Dame M, Petkovich M, Cyp26b1 expression in murine Sertoli cells is required to maintain male germ cells in an undifferentiated state during embryogenesis. PLoS One. 2009;4(10):e7501 |
1 | J:347973 Li Y, Wu Y, Khan I, Zhou J, Lu Y, Ye J, Liu J, Xie X, Hu C, Jiang H, Fan S, Zhang H, Zhang Y, Jiang X, Xu B, Ma H, Shi Q, M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination. EMBO Rep. 2023 Feb 6;24(2):e55778 |
1* | J:286886 Lim CH, Brower JV, Resnick JL, Oh SP, Terada N, Adenine nucleotide translocase 4 is expressed within embryonic ovaries and dispensable during oogenesis. Reprod Sci. 2015 Feb;22(2):250-7 |
1 | J:126705 MacLean G, Li H, Metzger D, Chambon P, Petkovich M, Apoptotic extinction of germ cells in testes of Cyp26b1 knockout mice. Endocrinology. 2007 Oct;148(10):4560-7 |
1 | J:296955 Niu W, Spradling AC, Two distinct pathways of pregranulosa cell differentiation support follicle formation in the mouse ovary. Proc Natl Acad Sci U S A. 2020 Aug 18;117(33):20015-20026 |
1* | J:140807 Otsuka S, Konno A, Hashimoto Y, Sasaki N, Endoh D, Kon Y, Oocytes in newborn MRL mouse testes. Biol Reprod. 2008 Jul;79(1):9-16 |
1 | J:197599 Pitetti JL, Calvel P, Romero Y, Conne B, Truong V, Papaioannou MD, Schaad O, Docquier M, Herrera PL, Wilhelm D, Nef S, Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice. PLoS Genet. 2013;9(1):e1003160 |
1* | J:209131 Saba R, Wu Q, Saga Y, CYP26B1 promotes male germ cell differentiation by suppressing STRA8-dependent meiotic and STRA8-independent mitotic pathways. Dev Biol. 2014 May 15;389(2):173-81 |
1 | J:342011 Shimada R, Kato Y, Takeda N, Fujimura S, Yasunaga KI, Usuki S, Niwa H, Araki K, Ishiguro KI, STRA8-RB interaction is required for timely entry of meiosis in mouse female germ cells. Nat Commun. 2023 Oct 25;14(1):6443 |
1* | J:242348 Soh YQS, Mikedis MM, Kojima M, Godfrey AK, de Rooij DG, Page DC, Meioc maintains an extended meiotic prophase I in mice. PLoS Genet. 2017 Apr;13(4):e1006704 |
1 | J:313675 Soygur B, Jaszczak RG, Fries A, Nguyen DH, Malki S, Hu G, Demir N, Arora R, Laird DJ, Intercellular bridges coordinate the transition from pluripotency to meiosis in mouse fetal oocytes. Sci Adv. 2021 Apr;7(15) |
1 | J:123269 Tachibana M, Nozaki M, Takeda N, Shinkai Y, Functional dynamics of H3K9 methylation during meiotic prophase progression. EMBO J. 2007 Jul 25;26(14):3346-59 |
1 | J:83946 Tay J, Hodgman R, Sarkissian M, Richter JD, Regulated CPEB phosphorylation during meiotic progression suggests a mechanism for temporal control of maternal mRNA translation. Genes Dev. 2003 Jun 15;17(12):1457-62 |
2 | J:102097 Tay J, Richter JD, Germ cell differentiation and synaptonemal complex formation are disrupted in CPEB knockout mice. Dev Cell. 2001 Aug;1(2):201-13 |
1* | J:133934 Tomizuka K, Horikoshi K, Kitada R, Sugawara Y, Iba Y, Kojima A, Yoshitome A, Yamawaki K, Amagai M, Inoue A, Oshima T, Kakitani M, R-spondin1 plays an essential role in ovarian development through positively regulating Wnt-4 signaling. Hum Mol Genet. 2008 May 1;17(9):1278-91 |
1 | J:281207 Vazquez BN, Blengini CS, Hernandez Y, Serrano L, Schindler K, SIRT7 promotes chromosome synapsis during prophase I of female meiosis. Chromosoma. 2019 Sep;128(3):369-383 |
1 | J:223223 Wu Q, Fukuda K, Weinstein M, Graff JM, Saga Y, SMAD2 and p38 signaling pathways act in concert to determine XY primordial germ cell fate in mice. Development. 2015 Feb 1;142(3):575-86 |
1 | J:180831 Xu B, Hua J, Zhang Y, Jiang X, Zhang H, Ma T, Zheng W, Sun R, Shen W, Sha J, Cooke HJ, Shi Q, Proliferating cell nuclear antigen (PCNA) regulates primordial follicle assembly by promoting apoptosis of oocytes in fetal and neonatal mouse ovaries. PLoS One. 2011;6(1):e16046 |
1 | J:356758 Yamaguchi S, Hong K, Liu R, Inoue A, Shen L, Zhang K, Zhang Y, Dynamics of 5-methylcytosine and 5-hydroxymethylcytosine during germ cell reprogramming. Cell Res. 2013 Mar;23(3):329-39 |
1 | J:194101 Yamaguchi S, Hong K, Liu R, Shen L, Inoue A, Diep D, Zhang K, Zhang Y, Tet1 controls meiosis by regulating meiotic gene expression. Nature. 2012 Dec 20;492(7429):443-7 |
1* | J:90277 Yao HH, Matzuk MM, Jorgez CJ, Menke DB, Page DC, Swain A, Capel B, Follistatin operates downstream of Wnt4 in mammalian ovary organogenesis. Dev Dyn. 2004 Jun;230(2):210-5 |
1 | J:353355 Yao X, Wang C, Yu W, Sun L, Lv Z, Xie X, Tian S, Yan L, Li L, Liu J, BCAS2 regulates oocyte meiotic prophase I by participating in mRNA alternative splicing. FASEB J. 2024 Jan;38(1):e23361 |
2 | J:362758 Zhang L, Li Y, Hu Y, Chen M, Cen C, Chen M, Lin L, Zhou J, Wang M, Cui X, Tang F, Gao F, Somatic cell-derived BMPs induce premature meiosis in male germ cells during the embryonic stage by upregulating Dazl expression. FASEB J. 2022 Feb;36(2):e22131 |
Syn1 synapsin I (Synonyms: Syn-1, Synapsin Ia, Synapsin Ib) | |
Results | Reference |
1 | J:297711 Kaplan MM, Flucher BE, Postsynaptic CaV1.1-driven calcium signaling coordinates presynaptic differentiation at the developing neuromuscular junction. Sci Rep. 2019 Dec 5;9(1):18450 |
1 | J:358157 N'Guetta PY, McLarnon SR, Tassou A, Geron M, Shirvan S, Hill RZ, Scherrer G, O'Brien LL, Comprehensive mapping of sensory and sympathetic innervation of the developing kidney. Cell Rep. 2024 Oct 22;43(10):114860 |
1 | J:178882 Odajima J, Wills ZP, Ndassa YM, Terunuma M, Kretschmannova K, Deeb TZ, Geng Y, Gawrzak S, Quadros IM, Newman J, Das M, Jecrois ME, Yu Q, Li N, Bienvenu F, Moss SJ, Greenberg ME, Marto JA, Sicinski P, Cyclin E constrains Cdk5 activity to regulate synaptic plasticity and memory formation. Dev Cell. 2011 Oct 18;21(4):655-68 |
2* | J:39572 Weiner JA, Chun J, Maternally derived immunoglobulin light chain is present in the fetal mammalian CNS. J Neurosci. 1997 May 1;17(9):3148-56 |
Syna syncytin a (Synonyms: Gm52, syncytin-A) | |
Results | Reference |
1* | J:253345 Bacquin A, Bireau C, Tanguy M, Romanet C, Vernochet C, Dupressoir A, Heidmann T, A Cell Fusion-Based Screening Method Identifies Glycosylphosphatidylinositol-Anchored Protein Ly6e as the Receptor for Mouse Endogenous Retroviral Envelope Syncytin-A. J Virol. 2017 Sep 15;91(18) |
1* | J:288988 Coudert AE, Redelsperger F, Chabbi-Achengli Y, Vernochet C, Marty C, Decrouy X, Heidmann T, de Vernejoul MC, Dupressoir A, Role of the captured retroviral envelope syncytin-B gene in the fusion of osteoclast and giant cell precursors and in bone resorption, analyzed ex vivo and in vivo in syncytin-B knockout mice. Bone Rep. 2019 Dec;11:100214 |
1 | J:180242 Dupressoir A, Vernochet C, Harper F, Guegan J, Dessen P, Pierron G, Heidmann T, A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1164-73 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
Synb syncytin b (Synonyms: D930020E02Rik, syncytin-B) | |
Results | Reference |
1 | J:331974 Cao C, Fleming MD, Loss of the placental iron exporter ferroportin 1 causes embryonic demise in late-gestation mouse pregnancy. Development. 2022 Dec 1;149(23):dev201160 |
2* | J:288988 Coudert AE, Redelsperger F, Chabbi-Achengli Y, Vernochet C, Marty C, Decrouy X, Heidmann T, de Vernejoul MC, Dupressoir A, Role of the captured retroviral envelope syncytin-B gene in the fusion of osteoclast and giant cell precursors and in bone resorption, analyzed ex vivo and in vivo in syncytin-B knockout mice. Bone Rep. 2019 Dec;11:100214 |
1 | J:180242 Dupressoir A, Vernochet C, Harper F, Guegan J, Dessen P, Pierron G, Heidmann T, A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1164-73 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
Syne2 spectrin repeat containing, nuclear envelope 2 (Synonyms: 6820443O06Rik, Cpfl8, D12Ertd777e, dice, diminished cone electroretinogram, mKIAA1011, Nesp2g, nesprin-2, syne-2) | |
Results | Reference |
2* | J:347982 Li C, Warren DT, Zhou C, De Silva S, Wilson DGS, Garcia-Maya M, Wheeler MA, Meinke P, Sawyer G, Ehler E, Wehnert M, Rao L, Zhang Q, Shanahan CM, Nesprin-2 is a novel scaffold protein for telethonin and FHL-2 in the cardiomyocyte sarcomere. J Biol Chem. 2024 Apr 2;300(5):107254 |
1 | J:252201 Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A, p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct;137(10):2157-2167 |
Syne3 spectrin repeat containing, nuclear envelope family member 3 (Synonyms: 4831426I19Rik, nesprin-3, nesprin-3alpha, nesprin-3beta) | |
Results | Reference |
2 | J:252201 Rapisarda V, Malashchuk I, Asamaowei IE, Poterlowicz K, Fessing MY, Sharov AA, Karakesisoglou I, Botchkarev VA, Mardaryev A, p63 Transcription Factor Regulates Nuclear Shape and Expression of Nuclear Envelope-Associated Genes in Epidermal Keratinocytes. J Invest Dermatol. 2017 Oct;137(10):2157-2167 |
Syngap1 synaptic Ras GTPase activating protein 1 homolog (rat) (Synonyms: Syngap) | |
Results | Reference |
1 | J:97490 Porter K, Komiyama NH, Vitalis T, Kind PC, Grant SG, Differential expression of two NMDA receptor interacting proteins, PSD-95 and SynGAP during mouse development. Eur J Neurosci. 2005 Jan;21(2):351-62 |
1* | J:334714 Yang R, Feng X, Arias-Cavieres A, Mitchell RM, Polo A, Hu K, Zhong R, Qi C, Zhang RS, Westneat N, Portillo CA, Nobrega MA, Hansel C, Garcia Iii AJ, Zhang X, Upregulation of SYNGAP1 expression in mice and human neurons by redirecting alternative splicing. Neuron. 2023 Mar 3; |
Synj1 synaptojanin 1 (Synonyms: A930006D20Rik, mKIAA0910) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Synpo synaptopodin (Synonyms: 9030217H17Rik, 9330140I15Rik) | |
Results | Reference |
1* | J:190090 Hasegawa S, Kume H, Iinuma S, Yamasaki M, Takahashi N, Fukui T, Acetoacetyl-CoA synthetase is essential for normal neuronal development. Biochem Biophys Res Commun. 2012 Oct 19;427(2):398-403 |
1 | J:326979 Taglienti M, Graf D, Schumacher V, Kreidberg JA, Bmp7 drives proximal tubule expansion and determines nephron number in the developing kidney. Development. 2022 Jul 15;149(14):dev200773 |
Syp synaptophysin (Synonyms: A230093K24Rik, p38, Syn, Syp I) | |
Results | Reference |
1 | J:227113 Amin ND, Bai G, Klug JR, Bonanomi D, Pankratz MT, Gifford WD, Hinckley CA, Sternfeld MJ, Driscoll SP, Dominguez B, Lee KF, Jin X, Pfaff SL, Loss of motoneuron-specific microRNA-218 causes systemic neuromuscular failure. Science. 2015 Dec 18;350(6267):1525-9 |
1 | J:126558 Chen F, Qian L, Yang ZH, Huang Y, Ngo ST, Ruan NJ, Wang J, Schneider C, Noakes PG, Ding YQ, Mei L, Luo ZG, Rapsyn interaction with calpain stabilizes AChR clusters at the neuromuscular junction. Neuron. 2007 Jul 19;55(2):247-60 |
1* | J:39412 Dechesne CJ, Kauff C, Stettler O, Tavitian B, Rab3A immunolocalization in the mammalian vestibular end-organs during development and comparison with synaptophysin expression. Brain Res Dev Brain Res. 1997 Mar 17;99(1):103-11 |
1 | J:252860 Dorninger F, Herbst R, Kravic B, Camurdanoglu BZ, Macinkovic I, Zeitler G, Forss-Petter S, Strack S, Khan MM, Waterham HR, Rudolf R, Hashemolhosseini S, Berger J, Reduced muscle strength in ether lipid-deficient mice is accompanied by altered development and function of the neuromuscular junction. J Neurochem. 2017 Dec;143(5):569-583 |
1 | J:102479 Fu AK, Ip FC, Fu WY, Cheung J, Wang JH, Yung WH, Ip NY, Aberrant motor axon projection, acetylcholine receptor clustering, and neurotransmission in cyclin-dependent kinase 5 null mice. Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15224-9 |
1 | J:80082 Herbst R, Avetisova E, Burden SJ, Restoration of synapse formation in Musk mutant mice expressing a Musk/Trk chimeric receptor. Development. 2002 Dec;129(23):5449-60 |
1 | J:261960 Ito H, Mizuno M, Noguchi K, Morishita R, Iwamoto I, Hara A, Nagata KI, Expression analyses of Phactr1 (phosphatase and actin regulator 1) during mouse brain development. Neurosci Res. 2018 Mar;128:50-57 |
1* | J:266603 Ito H, Morishita R, Mizuno M, Kawamura N, Tabata H, Nagata KI, Biochemical and Morphological Characterization of a Neurodevelopmental Disorder-Related Mono-ADP-Ribosylhydrolase, MACRO Domain Containing 2. Dev Neurosci. 2018;40(3):278-287 |
1 | J:140163 Lin S, Maj M, Bezakova G, Magyar JP, Brenner HR, Ruegg MA, Muscle-wide secretion of a miniaturized form of neural agrin rescues focal neuromuscular innervation in agrin mutant mice. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11406-11 |
1 | J:99854 Lin W, Dominguez B, Yang J, Aryal P, Brandon EP, Gage FH, Lee KF, Neurotransmitter acetylcholine negatively regulates neuromuscular synapse formation by a Cdk5-dependent mechanism. Neuron. 2005 May 19;46(4):569-79 |
1 | J:60191 Lin W, Sanchez HB, Deerinck T, Morris JK, Ellisman M, Lee KF, Aberrant development of motor axons and neuromuscular synapses in erbB2-deficient mice. Proc Natl Acad Sci U S A. 2000 Feb 1;97(3):1299-304 |
1 | J:250166 Liu K, Lei R, Li Q, Wang XX, Wu Q, An P, Zhang J, Zhu M, Xu Z, Hong Y, Wang F, Shen Y, Li H, Li H, Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity. Sci Rep. 2016 Feb 16;6:21019 |
1 | J:175241 Mohseni P, Sung HK, Murphy AJ, Laliberte CL, Pallari HM, Henkelman M, Georgiou J, Xie G, Quaggin SE, Thorner PS, Eriksson JE, Nagy A, Nestin Is Not Essential for Development of the CNS But Required for Dispersion of Acetylcholine Receptor Clusters at the Area of Neuromuscular Junctions. J Neurosci. 2011 Aug 10;31(32):11547-11552 |
1 | J:178379 Richard AF, Demignon J, Sakakibara I, Pujol J, Favier M, Strochlic L, Le Grand F, Sgarioto N, Guernec A, Schmitt A, Cagnard N, Huang R, Legay C, Guillet-Deniau I, Maire P, Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression. Dev Biol. 2011 Nov 15;359(2):303-20 |
1 | J:149890 Saiga T, Fukuda T, Matsumoto M, Tada H, Okano HJ, Okano H, Nakayama KI, Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development. Mol Cell Biol. 2009 Jul;29(13):3529-43 |
1 | J:246732 Saller MM, Huettl RE, Hanuschick P, Amend AL, Alberton P, Aszodi A, Huber AB, The role of Sema3-Npn-1 signaling during diaphragm innervation and muscle development. J Cell Sci. 2016 Sep 01;129(17):3295-308 |
1* | J:42766 Sang Q, Young HM, Development of nicotinic receptor clusters and innervation accompanying the change in muscle phenotype in the mouse esophagus. J Comp Neurol. 1997 Sep 15;386(1):119-36 |
1 | J:338071 Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn LJ, Rosenthal B, Gurtler M, Estanboulieh RR, Shvartsman D, Gifford DK, Trapnell C, Melton D, A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets. Cell. 2019 Feb 7;176(4):790-804.e13 |
1 | J:73913 Tisay KT, St John JA, Key B, Expression of specific glycoconjugates in both primary and secondary olfactory pathways in BALB/C mice. J Comp Neurol. 2002 Feb 11;443(3):213-25 |
1 | J:64148 Vannucchi MG, Faussone-Pellegrini MS, Synapse formation during neuron differentiation: An in situ study of the myenteric plexus during murine embryonic life. J Comp Neurol. 2000 Sep 25;425(3):369-81 |
1 | J:152457 Wang Z, Wang B, Yang L, Guo Q, Aithmitti N, Songyang Z, Zheng H, Presynaptic and postsynaptic interaction of the amyloid precursor protein promotes peripheral and central synaptogenesis. J Neurosci. 2009 Sep 2;29(35):10788-801 |
1 | J:185531 Wu H, Lu Y, Barik A, Joseph A, Taketo MM, Xiong WC, Mei L, beta-Catenin gain of function in muscles impairs neuromuscular junction formation. Development. 2012 Jul;139(13):2392-404 |
Syt1 synaptotagmin I (Synonyms: G630098F17Rik) | |
Results | Reference |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1 | J:226819 Coate TM, Spita NA, Zhang KD, Isgrig KT, Kelley MW, Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife. 2015;4 |
1* | J:243480 Gomez-Herreros F, Schuurs-Hoeijmakers JH, McCormack M, Greally MT, Rulten S, Romero-Granados R, Counihan TJ, Chaila E, Conroy J, Ennis S, Delanty N, Cortes-Ledesma F, de Brouwer AP, Cavalleri GL, El-Khamisy SF, de Vries BB, Caldecott KW, TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function. Nat Genet. 2014 May;46(5):516-21 |
1* | J:263979 Harley RJ, Murdy JP, Wang Z, Kelly MC, Ropp TF, Park SH, Maness PF, Manis PB, Coate TM, Neuronal cell adhesion molecule (NrCAM) is expressed by sensory cells in the cochlea and is necessary for proper cochlear innervation and sensory domain patterning during development. Dev Dyn. 2018 Mar 14; |
1* | J:114661 Lyu YL, Lin CP, Azarova AM, Cai L, Wang JC, Liu LF, Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Mol Cell Biol. 2006 Nov;26(21):7929-41 |
1 | J:201069 Stubbusch J, Narasimhan P, Huber K, Unsicker K, Rohrer H, Ernsberger U, Synaptic protein and pan-neuronal gene expression and their regulation by Dicer-dependent mechanisms differ between neurons and neuroendocrine cells. Neural Dev. 2013 Aug 20;8(1):16 |
Syt2 synaptotagmin II | |
Results | Reference |
1 | J:134988 Liu Y, Padgett D, Takahashi M, Li H, Sayeed A, Teichert RW, Olivera BM, McArdle JJ, Green WN, Lin W, Essential roles of the acetylcholine receptor {gamma}-subunit in neuromuscular synaptic patterning. Development. 2008 Jun;135(11):1957-67 |
1 | J:273796 Liu Y, Sugiura Y, Chen F, Lee KF, Ye Q, Lin W, Blocking skeletal muscle DHPRs/Ryr1 prevents neuromuscular synapse loss in mutant mice deficient in type III Neuregulin 1 (CRD-Nrg1). PLoS Genet. 2019 Mar;15(3):e1007857 |
Syt4 synaptotagmin IV | |
Results | Reference |
1 | J:181188 Aoki H, Hara A, Era T, Kunisada T, Yamada Y, Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development. 2012 Feb;139(4):667-77 |
1 | J:98945 Ballas N, Grunseich C, Lu DD, Speh JC, Mandel G, REST and its corepressors mediate plasticity of neuronal gene chromatin throughout neurogenesis. Cell. 2005 May 20;121(4):645-57 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
Syt6 synaptotagmin VI (Synonyms: 3110037A08Rik) | |
Results | Reference |
1 | J:357469 Sivori M, Dempsey B, Chettouh Z, Boismoreau F, Ayerdi M, et al., The pelvic organs receive no parasympathetic innervation. Elife. 2024;15 |
Syt9 synaptotagmin IX (Synonyms: Sytv) | |
Results | Reference |
1* | J:121917 Olesen C, Nyeng P, Kalisz M, Jensen TH, Moller M, Tommerup N, Byskov AG, Global gene expression analysis in fetal mouse ovaries with and without meiosis and comparison of selected genes with meiosis in the testis. Cell Tissue Res. 2007 Apr;328(1):207-21 |
Syt13 synaptotagmin XIII (Synonyms: 5730409J20Rik) | |
Results | Reference |
2 | J:327292 Bakhti M, Bastidas-Ponce A, Tritschler S, Czarnecki O, Tarquis-Medina M, Nedvedova E, Jaki J, Willmann SJ, Scheibner K, Cota P, Salinno C, Boldt K, Horn N, Ueffing M, Burtscher I, Theis FJ, Coskun U, Lickert H, Synaptotagmin-13 orchestrates pancreatic endocrine cell egression and islet morphogenesis. Nat Commun. 2022 Aug 4;13(1):4540 |
T brachyury, T-box transcription factor T (Synonyms: Bra, T1, Tbxt) | |
Results | Reference |
2* | J:238590 Hayashi K, Ikari T, Sugiyama G, Sugiura T, Ohyama Y, Kumamaru W, Shirasuna K, Mori Y, Involvement of the T-box transcription factor Brachyury in early-stage embryonic mouse salivary gland. Biochem Biophys Res Commun. 2016 Sep 02;477(4):814-9 |
1* | J:36233 Larue L, Antos C, Butz S, Huber O, Delmas V, Dominis M, Kemler R, A role for cadherins in tissue formation. Development. 1996 Oct;122(10):3185-94 |
Tab1 TGF-beta activated kinase 1/MAP3K7 binding protein 1 (Synonyms: 2310012M03Rik, b2b449Clo, Map3k7ip1, Tak1-binding protein 1) | |
Results | Reference |
1* | J:140317 Inagaki M, Komatsu Y, Scott G, Yamada G, Ray M, Ninomiya-Tsuji J, Mishina Y, Generation of a conditional mutant allele for Tab1 in mouse. Genesis. 2008 Aug;46(8):431-9 |
Tab2 TGF-beta activated kinase 1/MAP3K7 binding protein 2 (Synonyms: 1110030N06Rik, A530078N03Rik, Map3k7ip2, mKIAA0733, Tak1 binding protein 2) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Tac1 tachykinin 1 (Synonyms: 4930528L02Rik, neurokinin 1, neurokinin A, NK-1, NK1, Nkna, PPT-A, PPTA, preprotachykinin A, SP, substance P) | |
Results | Reference |
1 | J:119559 Bouwman J, Spijker S, Schut D, Wachtler B, Ylstra B, Smit AB, Verhage M, Reduced expression of neuropeptide genes in a genome-wide screen of a secretion-deficient mouse. J Neurochem. 2006 Oct;99(1):84-96 |
1 | J:85092 Funakoshi K, Goris RC, Kadota T, Atobe Y, Nakano M, Kishida R, Prenatal development of peptidergic primary afferent projections to mouse lumbosacral autonomic preganglionic cell columns. Brain Res Dev Brain Res. 2003 Aug 12;144(1):107-19 |
1 | J:361228 Li Z, Shang Z, Sun M, Jiang X, Tian Y, Yang L, Wang Z, Su Z, Liu G, Li X, You Y, Yang Z, Xu Z, Zhang Z, Transcription factor Sp9 is a negative regulator of D1-type MSN development. Cell Death Discov. 2022 Jun 30;8(1):301 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
1 | J:328873 Shang Z, Yang L, Wang Z, Tian Y, Gao Y, Su Z, Guo R, Li W, Liu G, Li X, Yang Z, Li Z, Zhang Z, The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity. Front Cell Dev Biol. 2022;10:948331 |
1* | J:28007 Weil M, Itin A, Keshet E, A role for mesenchyme-derived tachykinins in tooth and mammary gland morphogenesis. Development. 1995 Aug;121(8):2419-28 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
1 | J:319016 Yan R, Huang T, Xie Z, Xia G, Qian H, Zhao X, Cheng L, Lmx1b controls peptide phenotypes in serotonergic and dopaminergic neurons. Acta Biochim Biophys Sin (Shanghai). 2013 May;45(5):345-52 |
1 | J:238868 Zhang Q, Zhang Y, Wang C, Xu Z, Liang Q, An L, Li J, Liu Z, You Y, He M, Mao Y, Chen B, Xiong ZQ, Rubenstein JL, Yang Z, The Zinc Finger Transcription Factor Sp9 Is Required for the Development of Striatopallidal Projection Neurons. Cell Rep. 2016 Aug 02;16(5):1431-44 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
Tacr1 tachykinin receptor 1 (Synonyms: neurokinin receptor 1, NK1-R, NK-1R, NK1 receptor, SPr, substance p receptor, Tac1r) | |
Results | Reference |
1* | J:196346 Burgold T, Voituron N, Caganova M, Tripathi PP, Menuet C, Tusi BK, Spreafico F, Bevengut M, Gestreau C, Buontempo S, Simeone A, Kruidenier L, Natoli G, Casola S, Hilaire G, Testa G, The H3K27 demethylase JMJD3 is required for maintenance of the embryonic respiratory neuronal network, neonatal breathing, and survival. Cell Rep. 2012 Nov 29;2(5):1244-58 |
1* | J:243896 Chevalier M, Cardoit L, Moreau M, Sans N, Montcouquiol M, Simmers J, Thoby-Brisson M, The embryonic development of hindbrain respiratory networks is unaffected by mutation of the planar polarity protein Scribble. Neuroscience. 2017 Aug 15;357:160-171 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1 | J:188329 Huang WH, Tupal S, Huang TW, Ward CS, Neul JL, Klisch TJ, Gray PA, Zoghbi HY, Atoh1 Governs the Migration of Postmitotic Neurons that Shape Respiratory Effectiveness at Birth and Chemoresponsiveness in Adulthood. Neuron. 2012 Sep 6;75(5):799-809 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
1 | J:155760 Rose MF, Ren J, Ahmad KA, Chao HT, Klisch TJ, Flora A, Greer JJ, Zoghbi HY, Math1 is essential for the development of hindbrain neurons critical for perinatal breathing. Neuron. 2009 Nov 12;64(3):341-54 |
1 | J:277837 Thoby-Brisson M, Bouvier J, Glasco DM, Stewart ME, Dean C, Murdoch JN, Champagnat J, Fortin G, Chandrasekhar A, Brainstem respiratory oscillators develop independently of neuronal migration defects in the Wnt/PCP mouse mutant looptail. PLoS One. 2012;7(2):e31140 |
1 | J:116180 Wallen-Mackenzie A, Gezelius H, Thoby-Brisson M, Nygard A, Enjin A, Fujiyama F, Fortin G, Kullander K, Vesicular glutamate transporter 2 is required for central respiratory rhythm generation but not for locomotor central pattern generation. J Neurosci. 2006 Nov 22;26(47):12294-307 |
1* | J:28007 Weil M, Itin A, Keshet E, A role for mesenchyme-derived tachykinins in tooth and mammary gland morphogenesis. Development. 1995 Aug;121(8):2419-28 |
1 | J:132276 Zanella S, Watrin F, Mebarek S, Marly F, Roussel M, Gire C, Diene G, Tauber M, Muscatelli F, Hilaire G, Necdin plays a role in the serotonergic modulation of the mouse respiratory network: implication for Prader-Willi syndrome. J Neurosci. 2008 Feb 13;28(7):1745-55 |
Tacr2 tachykinin receptor 2 (Synonyms: Tac2r) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Tacr3 tachykinin receptor 3 (Synonyms: neuromedin K receptor, Nk3r, Tac3r) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
Tacstd2 tumor-associated calcium signal transducer 2 (Synonyms: EGP-1, GA733-1, Ly97, TROP2) | |
Results | Reference |
1* | J:203768 Mustata RC, Vasile G, Fernandez-Vallone V, Strollo S, Lefort A, Libert F, Monteyne D, Perez-Morga D, Vassart G, Garcia MI, Identification of Lgr5-independent spheroid-generating progenitors of the mouse fetal intestinal epithelium. Cell Rep. 2013 Oct 31;5(2):421-32 |
Taf1 TATA-box binding protein associated factor 1 (Synonyms: B430306D02Rik, Ccg-1, Ccg1, KAT4, Taf2a) | |
Results | Reference |
2 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
Taf3 TATA-box binding protein associated factor 3 (Synonyms: 4933439M23Rik, mTAFII140) | |
Results | Reference |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
Taf4 TATA-box binding protein associated factor 4 (Synonyms: Taf2c1, Taf4a, TAFII130, TAFII135) | |
Results | Reference |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
Taf5 TATA-box binding protein associated factor 5 (Synonyms: 6330528C20Rik) | |
Results | Reference |
2 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
Taf6 TATA-box binding protein associated factor 6 (Synonyms: 80kDa, p80, Taf2e) | |
Results | Reference |
2 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
Taf7 TATA-box binding protein associated factor 7 (Synonyms: 55kDa, Taf2f, TAFII55) | |
Results | Reference |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
Taf8 TATA-box binding protein associated factor 8 (Synonyms: Taf8, Tbn) | |
Results | Reference |
2 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
Taf10 TATA-box binding protein associated factor 10 (Synonyms: 30kDa, Taf2h, TAFII30) | |
Results | Reference |
2 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Taf11 TATA-box binding protein associated factor 11 (Synonyms: 1110038O14Rik, 28kDa, PRO214, TAF2I, TAFII28) | |
Results | Reference |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
Taf12 TATA-box binding protein associated factor 12 (Synonyms: 20kDa, 2810422D08Rik, Taf2J) | |
Results | Reference |
2 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
Taf13 TATA-box binding protein associated factor 13 (Synonyms: 1810004N01Rik, 2010309N11Rik) | |
Results | Reference |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
Tafa1 TAFA chemokine like family member 1 (Synonyms: C630007B19Rik, Fam19a1, Tafa-1) | |
Results | Reference |
1* | J:292915 Yong HJ, Ha N, Cho EB, Yun S, Kim H, Hwang JI, Seong JY, The unique expression profile of FAM19A1 in the mouse brain and its association with hyperactivity, long-term memory and fear acquisition. Sci Rep. 2020 Mar 2;10(1):3969 |
1 | J:271709 Zheng C, Chen D, Zhang Y, Bai Y, Huang S, Zheng D, Liang W, She S, Peng X, Wang P, Mo X, Song Q, Lv P, Huang J, Ye RD, Wang Y, FAM19A1 is a new ligand for GPR1 that modulates neural stem-cell proliferation and differentiation. FASEB J. 2018 May 25;:fj201800020RRR |
Tafa2 TAFA chemokine like family member 2 (Synonyms: Fam19a2, Sam2, Tafa-2, Tafa2) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Tafa5 TAFA chemokine like family member 5 (Synonyms: Fam19a5, Tara-5) | |
Results | Reference |
1 | J:360963 Huang S, Zheng C, Xie G, Song Z, Wang P, Bai Y, Chen D, Zhang Y, Lv P, Liang W, She S, Li Q, Liu Z, Wang Y, Xing GG, Wang Y, FAM19A5/TAFA5, a novel neurokine, plays a crucial role in depressive-like and spatial memory-related behaviors in mice. Mol Psychiatry. 2021 Jun;26(6):2363-2379 |
Tagln transgelin (Synonyms: SM22, Sm22a, SM-22 alpha, SM22alpha) | |
Results | Reference |
2 | J:124898 Ai X, Kitazawa T, Do AT, Kusche-Gullberg M, Labosky PA, Emerson CP Jr, SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation. Development. 2007 Sep;134(18):3327-38 |
1 | J:106499 Airik R, Bussen M, Singh MK, Petry M, Kispert A, Tbx18 regulates the development of the ureteral mesenchyme. J Clin Invest. 2006 Mar;116(3):663-74 |
1 | J:166547 Airik R, Trowe MO, Foik A, Farin HF, Petry M, Schuster-Gossler K, Schweizer M, Scherer G, Kist R, Kispert A, Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme. Hum Mol Genet. 2010 Dec 15;19(24):4918-29 |
1 | J:176638 Albinsson S, Suarez Y, Skoura A, Offermanns S, Miano JM, Sessa WC, MicroRNAs are necessary for vascular smooth muscle growth, differentiation, and function. Arterioscler Thromb Vasc Biol. 2010 Jun;30(6):1118-26 |
1 | J:245883 Aldeiri B, Roostalu U, Albertini A, Wong J, Morabito A, Cossu G, Transgelin-expressing myofibroblasts orchestrate ventral midline closure through TGFbeta signalling. Development. 2017 Sep 15;144(18):3336-3348 |
1* | J:272619 Aydogdu N, Rudat C, Trowe MO, Kaiser M, Ludtke TH, Taketo MM, Christoffels VM, Moon A, Kispert A, TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827 |
1 | J:262819 Bohnenpoll T, Feraric S, Nattkemper M, Weiss AC, Rudat C, Meuser M, Trowe MO, Kispert A, Diversification of Cell Lineages in Ureter Development. J Am Soc Nephrol. 2017 Jun;28(6):1792-1801 |
1 | J:244068 Bohnenpoll T, Wittern AB, Mamo TM, Weiss AC, Rudat C, Kleppa MJ, Schuster-Gossler K, Wojahn I, Ludtke TH, Trowe MO, Kispert A, A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development. PLoS Genet. 2017 Aug;13(8):e1006951 |
1* | J:264603 Da Silva F, Massa F, Motamedi FJ, Vidal V, Rocha AS, Gregoire EP, Cai CL, Wagner KD, Schedl A, Myocardial-specific R-spondin3 drives proliferation of the coronary stems primarily through the Leucine Rich Repeat G Protein coupled receptor LGR4. Dev Biol. 2018 Sep 1;441(1):42-51 |
2 | J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767 |
1 | J:339855 Gannoun L, De Schrevel C, Belle M, Dauguet N, Achouri Y, Loriot A, Vanderaa C, Cordi S, Dili A, Heremans Y, Rooman I, Leclercq IA, Jacquemin P, Gatto L, Lemaigre FP, Axon guidance genes control hepatic artery development. Development. 2023 Aug 15;150(16):dev201642 |
2 | J:294628 Gong H, Ni J, Xu Z, Huang J, Zhang J, Huang Y, Zeng C, Zhang X, Cheng H, Ke Y, Shp2 in myocytes is essential for cardiovascular and neointima development. J Mol Cell Cardiol. 2019 Dec;137:71-81 |
1 | J:239364 Ivins S, Chappell J, Vernay B, Suntharalingham J, Martineau A, Mohun TJ, Scambler PJ, The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development. Dev Cell. 2015 May 26;33(4):455-68 |
1 | J:316525 Kaku Y, Ohmori T, Kudo K, Fujimura S, Suzuki K, Evans SM, Kawakami Y, Nishinakamura R, Islet1 deletion causes kidney agenesis and hydroureter resembling CAKUT. J Am Soc Nephrol. 2013 Jul;24(8):1242-9 |
1 | J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522 |
2* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1* | J:32678 Li L, Miano JM, Cserjesi P, Olson EN, SM22 alpha, a marker of adult smooth muscle, is expressed in multiple myogenic lineages during embryogenesis. Circ Res. 1996 Feb;78(2):188-95 |
1* | J:75939 Li WE, Waldo K, Linask KL, Chen T, Wessels A, Parmacek MS, Kirby ML, Lo CW, An essential role for connexin43 gap junctions in mouse coronary artery development. Development. 2002 Apr;129(8):2031-42 |
1 | J:73145 Lu MM, Yang H, Zhang L, Shu W, Blair DG, Morrisey EE, The bone morphogenic protein antagonist gremlin regulates proximal-distal patterning of the lung. Dev Dyn. 2001 Dec;222(4):667-80 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:243772 Mamo TM, Wittern AB, Kleppa MJ, Bohnenpoll T, Weiss AC, Kispert A, BMP4 uses several different effector pathways to regulate proliferation and differentiation in the epithelial and mesenchymal tissue compartments of the developing mouse ureter. Hum Mol Genet. 2017 Sep 15;26(18):3553-3563 |
1 | J:202129 Martin E, Caubit X, Airik R, Vola C, Fatmi A, Kispert A, Fasano L, TSHZ3 and SOX9 regulate the timing of smooth muscle cell differentiation in the ureter by reducing myocardin activity. PLoS One. 2013;8(5):e63721 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
1 | J:156690 Morimoto M, Liu Z, Cheng HT, Winters N, Bader D, Kopan R, Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate. J Cell Sci. 2010 Jan 15;123(Pt 2):213-24 |
1 | J:170647 Mundell NA, Labosky PA, Neural crest stem cell multipotency requires Foxd3 to maintain neural potential and repress mesenchymal fates. Development. 2011 Feb;138(4):641-52 |
1 | J:157941 Nie X, Sun J, Gordon RE, Cai CL, Xu PX, SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation. Development. 2010 Mar;137(5):755-65 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:339839 Ross JA, Arcos-Villacis N, Battey E, Boogerd C, Orellana CA, Marhuenda E, Swiatlowska P, Hodzic D, Prin F, Mohun T, Catibog N, Tapia O, Gerace L, Iskratsch T, Shah AM, Stroud MJ, Lem2 is essential for cardiac development by maintaining nuclear integrity. Cardiovasc Res. 2023 Sep 5;119(11):2074-2088 |
1 | J:188834 Shen D, Li J, Lepore JJ, Anderson TJ, Sinha S, Lin AY, Cheng L, Cohen ED, Roberts JD Jr, Dedhar S, Parmacek MS, Gerszten RE, Aortic aneurysm generation in mice with targeted deletion of integrin-linked kinase in vascular smooth muscle cells. Circ Res. 2011 Sep 2;109(6):616-28 |
1 | J:178150 Singh MK, Lu MM, Massera D, Epstein JA, MicroRNA-processing Enzyme Dicer Is Required in Epicardium for Coronary Vasculature Development. J Biol Chem. 2011 Nov 25;286(47):41036-45 |
1 | J:361958 Straube P, Beckers A, Jany UWH, Bergmann F, Ludtke TH, Rudat C, Trowe MO, Peters I, Klopf MG, Mamo TM, Kispert A, Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter. Development. 2025 Feb 1;152(3) |
1 | J:171513 Tian Y, Zhang Y, Hurd L, Hannenhalli S, Liu F, Lu MM, Morrisey EE, Regulation of lung endoderm progenitor cell behavior by miR302/367. Development. 2011 Apr;138(7):1235-45 |
1 | J:311811 Trowe MO, Airik R, Weiss AC, Farin HF, Foik AB, Bettenhausen E, Schuster-Gossler K, Taketo MM, Kispert A, Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter. Development. 2012 Sep;139(17):3099-108 |
1 | J:233746 Wang X, Wang Y, Snitow ME, Stewart KM, Li S, Lu M, Morrisey EE, Expression of histone deacetylase 3 instructs alveolar type I cell differentiation by regulating a Wnt signaling niche in the lung. Dev Biol. 2016 Jun 15;414(2):161-9 |
2 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:214811 Weiss AC, Airik R, Bohnenpoll T, Greulich F, Foik A, Trowe MO, Rudat C, Costantini F, Adams RH, Kispert A, Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme. Development. 2014 Sep;141(17):3420-30 |
1* | J:279388 Weiss AC, Bohnenpoll T, Kurz J, Blank P, Airik R, Ludtke TH, Kleppa MJ, Deuper L, Kaiser M, Mamo TM, Costa R, von Hahn T, Trowe MO, Kispert A, Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme. J Pathol. 2019 Aug;248(4):452-463 |
1 | J:340973 Wojahn I, Ludtke TH, Christoffels VM, Trowe MO, Kispert A, TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung. Respir Res. 2019 Dec 23;20(1):292 |
1 | J:193198 Wu B, Zhang Z, Lui W, Chen X, Wang Y, Chamberlain AA, Moreno-Rodriguez RA, Markwald RR, O'Rourke BP, Sharp DJ, Zheng D, Lenz J, Baldwin HS, Chang CP, Zhou B, Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling. Cell. 2012 Nov 21;151(5):1083-96 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
Tagln2 transgelin 2 (Synonyms: 2700094C18Rik, Sm22B) | |
Results | Reference |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Tagln3 transgelin 3 (Synonyms: 2700038H05Rik, 2900005O10Rik, Np25) | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Tal1 T cell acute lymphocytic leukemia 1 (Synonyms: bHLHa17, Hpt, Scl, SCL/tal-1) | |
Results | Reference |
1 | J:170540 Jeong Y, Dolson DK, Waclaw RR, Matise MP, Sussel L, Campbell K, Kaestner KH, Epstein DJ, Spatial and temporal requirements for sonic hedgehog in the regulation of thalamic interneuron identity. Development. 2011 Feb;138(3):531-41 |
1 | J:244498 Lee B, Lee M, Song S, Loi LD, Lam DT, Yoon J, Baek K, Curtis DJ, Jeong Y, Specification of neurotransmitter identity by Tal1 in thalamic nuclei. Dev Dyn. 2017 Oct;246(10):749-758 |
1 | J:218837 Song H, Lee B, Pyun D, Guimera J, Son Y, Yoon J, Baek K, Wurst W, Jeong Y, Ascl1 and Helt act combinatorially to specify thalamic neuronal identity by repressing Dlxs activation. Dev Biol. 2015 Feb 15;398(2):280-91 |
1* | J:287411 Tran HN, Park W, Seong S, Jeong JE, Nguyen QH, Yoon J, Baek K, Jeong Y, Tcf7l2 transcription factor is required for the maintenance, but not the initial specification, of the neurotransmitter identity in the caudal thalamus. Dev Dyn. 2020 May;249(5):646-655 |
Tango6 transport and golgi organization 6 (Synonyms: Tango6, Tmco7) | |
Results | Reference |
1 | J:346124 Feng Z, Liu S, Su M, Song C, Lin C, Zhao F, Li Y, Zeng X, Zhu Y, Hou Y, Ren C, Zhang H, Yi P, Ji Y, Wang C, Li H, Ma M, Luo L, Li L, TANGO6 regulates cell proliferation via COPI vesicle-mediated RPB2 nuclear entry. Nat Commun. 2024 Mar 15;15(1):2371 |
Tardbp TAR DNA binding protein (Synonyms: 1190002A23Rik, Tdp43, TDP-43) | |
Results | Reference |
1* | J:159888 Sephton CF, Good SK, Atkin S, Dewey CM, Mayer P rd, Herz J, Yu G, TDP-43 is a developmentally regulated protein essential for early embryonic development. J Biol Chem. 2010 Feb 26;285(9):6826-34 |
Tasor transcription activation suppressor (Synonyms: 4933409E02Rik, D14Abb1e, Fam208a, MommeD6) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Tat tyrosine aminotransferase (Synonyms: MGC:37772, MGC:37789, MGC:37790, MGC:37819, MGC:37828, MGC:37842) | |
Results | Reference |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
1* | J:146970 Li T, Huang J, Jiang Y, Zeng Y, He F, Zhang MQ, Han Z, Zhang X, Multi-stage analysis of gene expression and transcription regulation in C57/B6 mouse liver development. Genomics. 2009 Mar;93(3):235-42 |
Tbata thymus, brain and testes associated (Synonyms: 1700021K02Rik, Spatial) | |
Results | Reference |
1* | J:102265 Flomerfelt FA, Kim MG, Schwartz RH, Spatial, a gene expressed in thymic stromal cells, depends on three-dimensional thymus organization for its expression. Genes Immun. 2000 Aug;1(6):391-401 |
Tbc1d1 TBC1 domain family, member 1 (Synonyms: 1110062G02Rik, mKIAA1108, Nob1, Nobq1) | |
Results | Reference |
1* | J:228878 Kosfeld A, Kreuzer M, Daniel C, Brand F, Schafer AK, Chadt A, Weiss AC, Riehmer V, Jeanpierre C, Klintschar M, Brasen JH, Amann K, Pape L, Kispert A, Al-Hasani H, Haffner D, Weber RG, Whole-exome sequencing identifies mutations of TBC1D1 encoding a Rab-GTPase-activating protein in patients with congenital anomalies of the kidneys and urinary tract (CAKUT). Hum Genet. 2016 Jan;135(1):69-87 |
Tbc1d22b TBC1 domain family, member 22B (Synonyms: MGC:31516, MGC:61359) | |
Results | Reference |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
Tbc1d24 TBC1 domain family, member 24 (Synonyms: C530046L02Rik, mKIAA1171) | |
Results | Reference |
2 | J:360774 Pepe S, Aprile D, Castroflorio E, Marte A, Giubbolini S, Hopestone S, Parsons A, Soares T, Benfenati F, Oliver PL, Fassio A, TBC1D24 interacts with the v-ATPase and regulates intraorganellar pH in neurons. iScience. 2025 Jan 17;28(1):111515 |
Tbcb tubulin folding cofactor B (Synonyms: 2410007D12Rik, Ckap1) | |
Results | Reference |
1* | J:119540 Lopez-Fanarraga M, Carranza G, Bellido J, Kortazar D, Villegas JC, Zabala JC, Tubulin cofactor B plays a role in the neuronal growth cone. J Neurochem. 2007 Mar;100(6):1680-7 |
Tbp TATA box binding protein (Synonyms: Gtf2d) | |
Results | Reference |
1 | J:111407 Beaudry JB, Pierreux CE, Hayhurst GP, Plumb-Rudewiez N, Weiss MC, Rousseau GG, Lemaigre FP, Threshold levels of hepatocyte nuclear factor 6 (HNF-6) acting in synergy with HNF-4 and PGC-1alpha are required for time-specific gene expression during liver development. Mol Cell Biol. 2006 Aug;26(16):6037-46 |
1 | J:173973 Benlhabib H, Mendelson CR, Epigenetic regulation of surfactant protein A gene (SP-A) expression in fetal lung reveals a critical role for Suv39h methyltransferases during development and hypoxia. Mol Cell Biol. 2011 May;31(10):1949-58 |
1* | J:120667 Bouzin C, Clotman F, Renauld JC, Lemaigre FP, Rousseau GG, The onecut transcription factor hepatocyte nuclear factor-6 controls B lymphopoiesis in fetal liver. J Immunol. 2003 Aug 1;171(3):1297-303 |
2 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
1 | J:30127 Kaestner KH, Monaghan AP, Kern H, Ang SL, Weitz S, Lichter P, Schutz G, The mouse fkh-2 gene. Implications for notochord, foregut, and midbrain regionalization. J Biol Chem. 1995 Dec 15;270(50):30029-35 |
1 | J:167091 Nyeng P, Bjerke MA, Norgaard GA, Qu X, Kobberup S, Jensen J, Fibroblast growth factor 10 represses premature cell differentiation during establishment of the intestinal progenitor niche. Dev Biol. 2011 Jan 1;349(1):20-34 |
Tbr1 T-box brain transcription factor 1 (Synonyms: T-box brain gene 1) | |
Results | Reference |
1 | J:306383 Ahmed R, Sarwar S, Hu J, Cardin V, Qiu LR, Zapata G, Vandeleur L, Yan K, Lerch JP, Corbett MA, Gecz J, Picketts DJ, Transgenic mice with an R342X mutation in Phf6 display clinical features of Borjeson-Forssman-Lehmann Syndrome. Hum Mol Genet. 2021 May 12;30(7):575-594 |
1 | J:350469 Alderman PJ, Saxon D, Torrijos-Saiz LI, Sharief M, Page CE, Baroudi JK, Biagiotti SW, Butyrkin VA, Melamed A, Kuo CT, Vicini S, Garcia-Verdugo JM, Herranz-Perez V, Corbin JG, Sorrells SF, Delayed maturation and migration of excitatory neurons in the juvenile mouse paralaminar amygdala. Neuron. 2024 Feb 21;112(4):574-592.e10 |
1 | J:178862 Alfano C, Viola L, Heng JI, Pirozzi M, Clarkson M, Flore G, De Maio A, Schedl A, Guillemot F, Studer M, COUP-TFI promotes radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression. Development. 2011 Nov;138(21):4685-97 |
1 | J:195145 Amaniti EM, Hasenpusch-Theil K, Li Z, Magnani D, Kessaris N, Mason JO, Theil T, Gli3 is required in Emx1(+) progenitors for the development of the corpus callosum. Dev Biol. 2013 Apr 15;376(2):113-24 |
1 | J:299451 Atkins A, Xu MJ, Li M, Rogers NP, Pryzhkova MV, Jordan PW, SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. Elife. 2020 Nov 17;9:e61171 |
1* | J:142365 Barry G, Piper M, Lindwall C, Moldrich R, Mason S, Little E, Sarkar A, Tole S, Gronostajski RM, Richards LJ, Specific glial populations regulate hippocampal morphogenesis. J Neurosci. 2008 Nov 19;28(47):12328-40 |
1 | J:162313 Bedogni F, Hodge RD, Elsen GE, Nelson BR, Daza RA, Beyer RP, Bammler TK, Rubenstein JL, Hevner RF, Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex. Proc Natl Acad Sci U S A. 2010 Jul 20;107(29):13129-34 |
1 | J:356256 Bertino F, Mukherjee D, Bonora M, Bagowski C, Nardelli J, Metani L, Zanin Venturini DI, Chianese D, Santander N, Salaroglio IC, Hentschel A, Quarta E, Genova T, McKinney AA, Allocco AL, Fiorito V, Petrillo S, Ammirata G, De Giorgio F, Dennis E, Allington G, Maier F, Shoukier M, Gloning KP, Munaron L, Mussano F, Salsano E, Pareyson D, di Rocco M, Altruda F, Panagiotakos G, Kahle KT, Gressens P, Riganti C, Pinton PP, Roos A, Arnold T, Tolosano E, Chiabrando D, Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus. Cell Rep Med. 2024 Jul 16;5(7):101647 |
1* | J:55094 Bulfone A, Martinez S, Marigo V, Campanella M, Basile A, Quaderi N, Gattuso C, Rubenstein JL, Ballabio A, Expression pattern of the Tbr2 (Eomesodermin) gene during mouse and chick brain development. Mech Dev. 1999 Jun;84(1-2):133-8 |
1* | J:27413 Bulfone A, Smiga SM, Shimamura K, Peterson A, Puelles L, Rubenstein JL, T-brain-1: a homolog of Brachyury whose expression defines molecularly distinct domains within the cerebral cortex. Neuron. 1995 Jul;15(1):63-78 |
1 | J:337815 Bunt J, Osinski JM, Lim JW, Vidovic D, Ye Y, Zalucki O, O'Connor TR, Harris L, Gronostajski RM, Richards LJ, Piper M, Combined allelic dosage of Nfia and Nfib regulates cortical development. Brain Neurosci Adv. 2017 Jan-Dec;1:2398212817739433 |
1 | J:159309 Buttner N, Johnsen SA, Kugler S, Vogel T, Af9/Mllt3 interferes with Tbr1 expression through epigenetic modification of histone H3K79 during development of the cerebral cortex. Proc Natl Acad Sci U S A. 2010 Apr 13;107(15):7042-7 |
1 | J:324533 Calderon L, Weiss FD, Beagan JA, Oliveira MS, Georgieva R, Wang YF, Carroll TS, Dharmalingam G, Gong W, Tossell K, de Paola V, Whilding C, Ungless MA, Fisher AG, Phillips-Cremins JE, Merkenschlager M, Cohesin-dependence of neuronal gene expression relates to chromatin loop length. Elife. 2022 Apr 26;11:e76539 |
1 | J:228026 Capecchi MR, Pozner A, ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination. Nat Commun. 2015;6:8763 |
1 | J:182669 Cappello S, Bohringer CR, Bergami M, Conzelmann KK, Ghanem A, Tomassy GS, Arlotta P, Mainardi M, Allegra M, Caleo M, van Hengel J, Brakebusch C, Gotz M, A radial glia-specific role of RhoA in double cortex formation. Neuron. 2012 Mar 8;73(5):911-24 |
1 | J:264379 Cardenas A, Villalba A, de Juan Romero C, Pico E, Kyrousi C, Tzika AC, Tessier-Lavigne M, Ma L, Drukker M, Cappello S, Borrell V, Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels. Cell. 2018 Jul 26;174(3):590-606.e21 |
1 | J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5 |
1 | J:107294 Chang Y, Ostling P, Akerfelt M, Trouillet D, Rallu M, Gitton Y, El Fatimy R, Fardeau V, Le Crom S, Morange M, Sistonen L, Mezger V, Role of heat-shock factor 2 in cerebral cortex formation and as a regulator of p35 expression. Genes Dev. 2006 Apr 1;20(7):836-47 |
1 | J:160586 Chen CM, Wang HY, You LR, Shang RL, Liu FC, Expression analysis of an evolutionary conserved metallophosphodiesterase gene, Mpped1, in the normal and beta-catenin-deficient malformed dorsal telencephalon. Dev Dyn. 2010 Jun;239(6):1797-806 |
1 | J:235552 Chinn GA, Hirokawa KE, Chuang TM, Urbina C, Patel F, Fong J, Funatsu N, Monuki ES, Agenesis of the Corpus Callosum Due to Defective Glial Wedge Formation in Lhx2 Mutant Mice. Cereb Cortex. 2015 Sep;25(9):2707-18 |
1 | J:264980 Coffinier C, Jung HJ, Nobumori C, Chang S, Tu Y, Barnes RH 2nd, Yoshinaga Y, de Jong PJ, Vergnes L, Reue K, Fong LG, Young SG, Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell. 2011 Dec;22(23):4683-93 |
1 | J:229227 Colasante G, Simonet JC, Calogero R, Crispi S, Sessa A, Cho G, Golden JA, Broccoli V, ARX regulates cortical intermediate progenitor cell expansion and upper layer neuron formation through repression of Cdkn1c. Cereb Cortex. 2015 Feb;25(2):322-35 |
1 | J:169370 Conway CD, Howe KM, Nettleton NK, Price DJ, Mason JO, Pratt T, Heparan sulfate sugar modifications mediate the functions of slits and other factors needed for mouse forebrain commissure development. J Neurosci. 2011 Feb 9;31(6):1955-70 |
1 | J:99355 Depaepe V, Suarez-Gonzalez N, Dufour A, Passante L, Gorski JA, Jones KR, Ledent C, Vanderhaeghen P, Ephrin signalling controls brain size by regulating apoptosis of neural progenitors. Nature. 2005 Jun 30;435(7046):1244-50 |
1 | J:192580 Diaz-Alonso J, Aguado T, Wu CS, Palazuelos J, Hofmann C, Garcez P, Guillemot F, Lu HC, Lutz B, Guzman M, Galve-Roperh I, The CB(1) cannabinoid receptor drives corticospinal motor neuron differentiation through the Ctip2/Satb2 transcriptional regulation axis. J Neurosci. 2012 Nov 21;32(47):16651-65 |
1* | J:78160 Faedo A, Ficara F, Ghiani M, Aiuti A, Rubenstein JL, Bulfone A, Developmental expression of the T-box transcription factor T-bet/Tbx21 during mouse embryogenesis. Mech Dev. 2002 Aug;116(1-2):157-60 |
1 | J:139119 Fan X, Kim HJ, Bouton D, Warner M, Gustafsson JA, Expression of liver X receptor beta is essential for formation of superficial cortical layers and migration of later-born neurons. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13445-50 |
1 | J:144651 Farkas LM, Haffner C, Giger T, Khaitovich P, Nowick K, Birchmeier C, Paabo S, Huttner WB, Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex. Neuron. 2008 Oct 9;60(1):40-55 |
1 | J:272744 Fawal MA, Jungas T, Kischel A, Audouard C, Iacovoni JS, Davy A, Cross Talk between One-Carbon Metabolism, Eph Signaling, and Histone Methylation Promotes Neural Stem Cell Differentiation. Cell Rep. 2018 Jun 5;23(10):2864-2873.e7 |
1 | J:94756 Feng Y, Walsh CA, Mitotic spindle regulation by Nde1 controls cerebral cortical size. Neuron. 2004 Oct 14;44(2):279-93 |
1 | J:250440 Ferguson R, Serafeimidou-Pouliou E, Subramanian V, Dynamic expression of the mouse orthologue of the human amyotropic lateral sclerosis associated gene C9orf72 during central nervous system development and neuronal differentiation. J Anat. 2016 Dec;229(6):871-891 |
1 | J:106708 Fink AJ, Englund C, Daza RA, Pham D, Lau C, Nivison M, Kowalczyk T, Hevner RF, Development of the deep cerebellar nuclei: transcription factors and cell migration from the rhombic lip. J Neurosci. 2006 Mar 15;26(11):3066-76 |
1* | J:205524 Fujimori A, Itoh K, Goto S, Hirakawa H, Wang B, Kokubo T, Kito S, Tsukamoto S, Fushiki S, Disruption of Aspm causes microcephaly with abnormal neuronal differentiation. Brain Dev. 2014 Sep;36(8):661-9 |
1 | J:360819 Gabriel GC, Yagi H, Tan T, Bais A, Glennon BJ, Stapleton MC, Huang L, Reynolds WT, Shaffer MG, Ganapathiraju M, Simon D, Panigrahy A, Wu YL, Lo CW, Mitotic block and epigenetic repression underlie neurodevelopmental defects and neurobehavioral deficits in congenital heart disease. Nat Commun. 2025 Jan 7;16(1):469 |
1 | J:179195 Georgala PA, Manuel M, Price DJ, The generation of superficial cortical layers is regulated by levels of the transcription factor Pax6. Cereb Cortex. 2011 Jan;21(1):81-94 |
1 | J:151321 Glickstein SB, Monaghan JA, Koeller HB, Jones TK, Ross ME, Cyclin D2 is critical for intermediate progenitor cell proliferation in the embryonic cortex. J Neurosci. 2009 Jul 29;29(30):9614-24 |
1 | J:206577 Green MJ, Myat AM, Emmenegger BA, Wechsler-Reya RJ, Wilson LJ, Wingate RJ, Independently specified Atoh1 domains define novel developmental compartments in rhombomere 1. Development. 2014 Jan;141(2):389-98 |
1* | J:207495 Green MJ, Wingate RJ, Developmental origins of diversity in cerebellar output nuclei. Neural Dev. 2014;9:1 |
1 | J:333012 Han X, Shen X, Wang M, Wang X, Jian Y, Yang C, Guo W, Loss of RNA-Binding Protein HuR Leads to Defective Ependymal Cells and Hydrocephalus. J Neurosci. 2022 Jan 12;42(2):202-219 |
1 | J:81763 Hebert JM, Lin M, Partanen J, Rossant J, McConnell SK, FGF signaling through FGFR1 is required for olfactory bulb morphogenesis. Development. 2003 Mar;130(6):1101-11 |
1 | J:82656 Hevner RF, Neogi T, Englund C, Daza RA, Fink A, Cajal-Retzius cells in the mouse: transcription factors, neurotransmitters, and birthdays suggest a pallial origin. Brain Res Dev Brain Res. 2003 Mar 14;141(1-2):39-53 |
1* | J:213614 Hirata-Fukae C, Hirata T, The zinc finger gene Fezf2 is required for the development of excitatory neurons in the basolateral complex of the amygdala. Dev Dyn. 2014 Aug;243(8):1030-6 |
1 | J:130251 Hori K, Cholewa-Waclaw J, Nakada Y, Glasgow SM, Masui T, Henke RM, Wildner H, Martarelli B, Beres TM, Epstein JA, Magnuson MA, Macdonald RJ, Birchmeier C, Johnson JE, A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes Dev. 2008 Jan 15;22(2):166-78 |
1 | J:294837 Huang C, Liu T, Wang Q, Hou W, Zhou C, Song Z, Shi YS, Gao X, Chen G, Yin Z, Hu Y, Loss of PP2A Disrupts the Retention of Radial Glial Progenitors in the Telencephalic Niche to Impair the Generation for Late-Born Neurons During Cortical Development. Cereb Cortex. 2020 Jun 1;30(7):4183-4196 |
2 | J:208050 Huang TN, Chuang HC, Chou WH, Chen CY, Wang HF, Chou SJ, Hsueh YP, Tbr1 haploinsufficiency impairs amygdalar axonal projections and results in cognitive abnormality. Nat Neurosci. 2014 Feb;17(2):240-7 |
1 | J:153525 Hurtado-Chong A, Yusta-Boyo MJ, Vergano-Vera E, Bulfone A, de Pablo F, Vicario-Abejon C, IGF-I promotes neuronal migration and positioning in the olfactory bulb and the exit of neuroblasts from the subventricular zone. Eur J Neurosci. 2009 Sep;30(5):742-55 |
1 | J:134970 Inoue T, Ogawa M, Mikoshiba K, Aruga J, Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly. J Neurosci. 2008 Apr 30;28(18):4712-25 |
1 | J:334107 Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J, Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice. Hum Mol Genet. 2022 Oct 10;31(20):3504-3520 |
1 | J:207606 Kahoud RJ, Elsen GE, Hevner RF, Hodge RD, Conditional ablation of Tbr2 results in abnormal development of the olfactory bulbs and subventricular zone-rostral migratory stream. Dev Dyn. 2014 Mar;243(3):440-50 |
1 | J:169455 Kim D, Ackerman SL, The UNC5C netrin receptor regulates dorsal guidance of mouse hindbrain axons. J Neurosci. 2011 Feb 9;31(6):2167-79 |
1 | J:160624 Kim S, Lehtinen MK, Sessa A, Zappaterra MW, Cho SH, Gonzalez D, Boggan B, Austin CA, Wijnholds J, Gambello MJ, Malicki J, LaMantia AS, Broccoli V, Walsh CA, The apical complex couples cell fate and cell survival to cerebral cortical development. Neuron. 2010 Apr 15;66(1):69-84 |
1* | J:289438 Kischel A, Audouard C, Fawal MA, Davy A, Ephrin-B2 paces neuronal production in the developing neocortex. BMC Dev Biol. 2020 May 13;20(1):12 |
1 | J:222255 Knock E, Pereira J, Lombard PD, Dimond A, Leaford D, Livesey FJ, Hendrich B, The methyl binding domain 3/nucleosome remodelling and deacetylase complex regulates neural cell fate determination and terminal differentiation in the cerebral cortex. Neural Dev. 2015;10:13 |
1 | J:132370 Konno D, Shioi G, Shitamukai A, Mori A, Kiyonari H, Miyata T, Matsuzaki F, Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis. Nat Cell Biol. 2008 Jan;10(1):93-101 |
1 | J:101055 Kuo G, Arnaud L, Kronstad-O'Brien P, Cooper JA, Absence of Fyn and Src causes a reeler-like phenotype. J Neurosci. 2005 Sep 14;25(37):8578-86 |
1 | J:343097 Kurabayashi N, Fujii K, Otobe Y, Hiroki S, Hiratsuka M, Yoshitane H, Kazuki Y, Takao K, Neocortical neuronal production and maturation defects in the TcMAC21 mouse model of Down syndrome. iScience. 2023 Dec 15;26(12):108379 |
1 | J:178681 Lakoma J, Garcia-Alonso L, Luque JM, Reelin sets the pace of neocortical neurogenesis. Development. 2011 Dec;138(23):5223-34 |
1 | J:317151 Lavado A, Gangwar R, Pare J, Wan S, Fan Y, Cao X, YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development. Dev Biol. 2021 Dec;480:39-49 |
1 | J:306873 Li L, Jin J, Yang XJ, Histone Deacetylase 3 Governs Perinatal Cerebral Development via Neural Stem and Progenitor Cells. iScience. 2019 Oct 25;20:148-167 |
2 | J:325428 Liu J, Yang M, Su M, Liu B, Zhou K, Sun C, Ba R, Yu B, Zhang B, Zhang Z, Fan W, Wang K, Zhong M, Han J, Zhao C, FOXG1 sequentially orchestrates subtype specification of postmitotic cortical projection neurons. Sci Adv. 2022 May 27;8(21):eabh3568 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:217046 Magnani D, Hasenpusch-Theil K, Benadiba C, Yu T, Basson MA, Price DJ, Lebrand C, Theil T, Gli3 controls corpus callosum formation by positioning midline guideposts during telencephalic patterning. Cereb Cortex. 2014 Jan;24(1):186-98 |
1 | J:179730 Mairet-Coello G, Tury A, Van Buskirk E, Robinson K, Genestine M, Dicicco-Bloom E, p57KIP2 regulates radial glia and intermediate precursor cell cycle dynamics and lower layer neurogenesis in developing cerebral cortex. Development. 2012 Feb;139(3):475-87 |
1 | J:338454 Marfull-Oromi P, Fleitas C, Zammou B, Rocandio D, Ballester-Lurbe B, Terrado J, Perez-Roger I, Espinet C, Egea J, Genetic ablation of the Rho GTPase Rnd3 triggers developmental defects in internal capsule and the globus pallidus formation. J Neurochem. 2021 Jul;158(2):197-216 |
1 | J:322988 Markert F, Storch A, Hyperoxygenation During Mid-Neurogenesis Accelerates Cortical Development in the Fetal Mouse Brain. Front Cell Dev Biol. 2022;10:732682 |
1* | J:257918 Massimino L, Flores-Garcia L, Di Stefano B, Colasante G, Icoresi-Mazzeo C, Zaghi M, Hamilton BA, Sessa A, TBR2 antagonizes retinoic acid dependent neuronal differentiation by repressing Zfp423 during corticogenesis. Dev Biol. 2018 Feb 15;434(2):231-248 |
1 | J:341276 Matrongolo MJ, Ho-Nguyen KT, Jain M, Ang PS, Reddy A, Schaper S, Tischfield MA, Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice. Development. 2023 Sep 15;150(18):dev201381 |
1 | J:306233 Mesman S, Bakker R, Smidt MP, Tcf4 is required for correct brain development during embryogenesis. Mol Cell Neurosci. 2020 Jul;106:103502 |
1 | J:238369 Mihalas AB, Elsen GE, Bedogni F, Daza RA, Ramos-Laguna KA, Arnold SJ, Hevner RF, Intermediate Progenitor Cohorts Differentially Generate Cortical Layers and Require Tbr2 for Timely Acquisition of Neuronal Subtype Identity. Cell Rep. 2016 Jun 28;16(1):92-105 |
1 | J:335191 Munz M, Bharioke A, Kosche G, Moreno-Juan V, Brignall A, Rodrigues TM, Graff-Meyer A, Ulmer T, Haeuselmann S, Pavlinic D, Ledergerber N, Gross-Scherf B, Rozsa B, Krol J, Picelli S, Cowan CS, Roska B, Pyramidal neurons form active, transient, multilayered circuits perturbed by autism-associated mutations at the inception of neocortex. Cell. 2023 Apr 27;186(9):1930-1949.e31 |
2 | J:314576 Narayanan R, Pirouz M, Kerimoglu C, Pham L, Wagener RJ, Kiszka KA, Rosenbusch J, Seong RH, Kessel M, Fischer A, Stoykova A, Staiger JF, Tuoc T, Loss of BAF (mSWI/SNF) Complexes Causes Global Transcriptional and Chromatin State Changes in Forebrain Development. Cell Rep. 2015 Dec 1;13(9):1842-54 |
1 | J:154587 Niquille M, Garel S, Mann F, Hornung JP, Otsmane B, Chevalley S, Parras C, Guillemot F, Gaspar P, Yanagawa Y, Lebrand C, Transient neuronal populations are required to guide callosal axons: a role for semaphorin 3C. PLoS Biol. 2009 Oct;7(10):e1000230 |
1 | J:240398 Ogino H, Hisanaga A, Kohno T, Kondo Y, Okumura K, Kamei T, Sato T, Asahara H, Tsuiji H, Fukata M, Hattori M, Secreted Metalloproteinase ADAMTS-3 Inactivates Reelin. J Neurosci. 2017 Mar 22;37(12):3181-3191 |
1 | J:151894 Oishi K, Watatani K, Itoh Y, Okano H, Guillemot F, Nakajima K, Gotoh Y, Selective induction of neocortical GABAergic neurons by the PDK1-Akt pathway through activation of Mash1. Proc Natl Acad Sci U S A. 2009 Aug 4;106(31):13064-9 |
1 | J:150768 Okado H, Ohtaka-Maruyama C, Sugitani Y, Fukuda Y, Ishida R, Hirai S, Miwa A, Takahashi A, Aoki K, Mochida K, Suzuki O, Honda T, Nakajima K, Ogawa M, Terashima T, Matsuda J, Kawano H, Kasai M, The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Dev Biol. 2009 Jul 15;331(2):140-51 |
1 | J:363605 Ortiz A, Ayhan F, Khandelwal N, Outland E, Jankovic M, Harper M, Konopka G, Cell-type-specific roles of FOXP1 in the excitatory neuronal lineage during early neocortical murine development. Cell Rep. 2025 Mar 5;44(3):115384 |
1 | J:287008 Pearson CA, Moore DM, Tucker HO, Dekker JD, Hu H, Miquelajauregui A, Novitch BG, Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates. Cell Rep. 2020 Feb 11;30(6):1964-1981.e3 |
1 | J:326380 Penisson M, Jin M, Wang S, Hirotsune S, Francis F, Belvindrah R, Lis1 mutation prevents basal radial glia-like cell production in the mouse. Hum Mol Genet. 2022 Mar 21;31(6):942-957 |
2 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:255488 Premarathne S, Murtaza M, Matigian N, Jolly LA, Wood SA, Loss of Usp9x disrupts cell adhesion, and components of the Wnt and Notch signaling pathways in neural progenitors. Sci Rep. 2017 Aug 14;7(1):8109 |
1 | J:185659 Pucilowska J, Puzerey PA, Karlo JC, Galan RF, Landreth GE, Disrupted ERK Signaling during Cortical Development Leads to Abnormal Progenitor Proliferation, Neuronal and Network Excitability and Behavior, Modeling Human Neuro-Cardio-Facial-Cutaneous and Related Syndromes. J Neurosci. 2012 Jun 20;32(25):8663-77 |
1 | J:236865 Ramesh V, Bayam E, Cernilogar FM, Bonapace IM, Schulze M, Riemenschneider MJ, Schotta G, Gotz M, Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration. Genes Dev. 2016 Oct 1;30(19):2199-2212 |
1 | J:187684 Rodriguez M, Choi J, Park S, Sockanathan S, Gde2 regulates cortical neuronal identity by controlling the timing of cortical progenitor differentiation. Development. 2012 Oct;139(20):3870-9 |
1 | J:123784 Romito-DiGiacomo RR, Menegay H, Cicero SA, Herrup K, Effects of Alzheimer's disease on different cortical layers: the role of intrinsic differences in Abeta susceptibility. J Neurosci. 2007 Aug 8;27(32):8496-504 |
1 | J:353313 Roussat M, Jungas T, Audouard C, Omerani S, Medevielle F, Agius E, Davy A, Pituello F, Bel-Vialar S, Control of G(2) Phase Duration by CDC25B Modulates the Switch from Direct to Indirect Neurogenesis in the Neocortex. J Neurosci. 2023 Feb 15;43(7):1154-1165 |
1 | J:269511 Roy A, Skibo J, Kalume F, Ni J, Rankin S, Lu Y, Dobyns WB, Mills GB, Zhao JJ, Baker SJ, Millen KJ, Mouse models of human PIK3CA-related brain overgrowth have acutely treatable epilepsy. Elife. 2015 Dec 3;4:e12703 |
1 | J:341708 Saha S, Jungas TT, Ohayon D, Audouard C, Ye T, Fawal MA, Davy A, Dihydrofolate reductase activity controls neurogenic transitions in the developing neocortex. Development. 2023 Oct 15;150(20):dev201696 |
1* | J:210661 Seto Y, Ishiwata S, Hoshino M, Characterization of Olig2 expression during cerebellar development. Gene Expr Patterns. 2014 May;15(1):1-7 |
1* | J:170671 Shibata M, Nakao H, Kiyonari H, Abe T, Aizawa S, MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22 |
1 | J:228291 Shinmyo Y, Asrafuzzaman Riyadh M, Ahmed G, Bin Naser I, Hossain M, Takebayashi H, Kawasaki H, Ohta K, Tanaka H, Draxin from neocortical neurons controls the guidance of thalamocortical projections into the neocortex. Nat Commun. 2015;6:10232 |
1 | J:184856 Shintani T, Takeuchi Y, Fujikawa A, Noda M, Directional neuronal migration is impaired in mice lacking adenomatous polyposis coli 2. J Neurosci. 2012 May 9;32(19):6468-84 |
1 | J:152951 Sillitoe RV, Gopal N, Joyner AL, Embryonic origins of ZebrinII parasagittal stripes and establishment of topographic Purkinje cell projections. Neuroscience. 2009 Sep 1;162(3):574-88 |
1 | J:214381 Spiegel I, Mardinly AR, Gabel HW, Bazinet JE, Couch CH, Tzeng CP, Harmin DA, Greenberg ME, Npas4 regulates excitatory-inhibitory balance within neural circuits through cell-type-specific gene programs. Cell. 2014 May 22;157(5):1216-29 |
1* | J:324710 Stanton-Turcotte D, Hsu K, Moore SA, Yamada M, Fawcett JP, Iulianella A, Mllt11 Regulates Migration and Neurite Outgrowth of Cortical Projection Neurons during Development. J Neurosci. 2022 May 11;42(19):3931-3948 |
1 | J:298594 Stepien BK, Naumann R, Holtz A, Helppi J, Huttner WB, Vaid S, Lengthening Neurogenic Period during Neocortical Development Causes a Hallmark of Neocortex Expansion. Curr Biol. 2020 Nov 2;30(21):4227-4237.e5 |
1 | J:159839 Stevens HE, Smith KM, Maragnoli ME, Fagel D, Borok E, Shanabrough M, Horvath TL, Vaccarino FM, Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits. J Neurosci. 2010 Apr 21;30(16):5590-602 |
1 | J:320749 Sun YY, Chen WJ, Huang ZP, Yang G, Wu ML, Xu DE, Yang WL, Luo YC, Xiao ZC, Xu RX, Ma QH, TRIM32 Deficiency Impairs the Generation of Pyramidal Neurons in Developing Cerebral Cortex. Cells. 2022 Jan 28;11(3) |
1 | J:188109 Tan SL, Nishi M, Ohtsuka T, Matsui T, Takemoto K, Kamio-Miura A, Aburatani H, Shinkai Y, Kageyama R, Essential roles of the histone methyltransferase ESET in the epigenetic control of neural progenitor cells during development. Development. 2012 Oct;139(20):3806-16 |
1 | J:278287 Tang T, Zhang Y, Wang Y, Cai Z, Lu Z, Li L, Huang R, Hagelkruys A, Matthias P, Zhang H, Seiser C, Xie Y, HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development. Neuron. 2019 Mar 20;101(6):1117-1133.e5 |
1 | J:98620 Tole S, Remedios R, Saha B, Stoykova A, Selective requirement of Pax6, but not Emx2, in the specification and development of several nuclei of the amygdaloid complex. J Neurosci. 2005 Mar 9;25(10):2753-60 |
1 | J:343099 Tonosaki M, Fujimori A, Yaoi T, Itoh K, Loss of Aspm causes increased apoptosis of developing neural cells during mouse cerebral corticogenesis. PLoS One. 2023;18(11):e0294893 |
1 | J:304564 Venkataramanappa S, Schutz D, Saaber F, Kumar PA, Abe P, Schulz S, Stumm R, The microcephaly gene Donson is essential for progenitors of cortical glutamatergic and GABAergic neurons. PLoS Genet. 2021 Mar;17(3):e1009441 |
1 | J:309451 Vinsland E, Baskaran P, Mihaylov SR, Hobbs C, Wood H, Bouybayoune I, Shah K, Houart C, Tee AR, Murn J, Fernandes C, Bateman JM, The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021 Aug 11;11(1):16299 |
1* | J:143543 Vogel T, Gruss P, Expression of Leukaemia associated transcription factor Af9/Mllt3 in the cerebral cortex of the mouse. Gene Expr Patterns. 2009 Feb;9(2):83-93 |
1 | J:265679 Wang B, Joo JH, Mount R, Teubner BJW, Krenzer A, Ward AL, Ichhaporia VP, Adams EJ, Khoriaty R, Peters ST, Pruett-Miller SM, Zakharenko SS, Ginsburg D, Kundu M, The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018 Aug 1;128(8):3319-3332 |
2 | J:94801 Wang TF, Ding CN, Wang GS, Luo SC, Lin YL, Ruan Y, Hevner R, Rubenstein JL, Hsueh YP, Identification of Tbr-1/CASK complex target genes in neurons. J Neurochem. 2004 Dec;91(6):1483-92 |
1 | J:299244 Wang Y, Guo Y, Tang C, Han X, Xu M, Sun J, Zhao Y, Zhang Y, Wang M, Cao X, Zhu X, Guo W, Developmental Cytoplasmic-to-Nuclear Translocation of RNA-Binding Protein HuR Is Required for Adult Neurogenesis. Cell Rep. 2019 Dec 3;29(10):3101-3117.e7 |
2 | J:184434 Xiang C, Baubet V, Pal S, Holderbaum L, Tatard V, Jiang P, Davuluri RV, Dahmane N, RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion. Cell Death Differ. 2012 Apr;19(4):692-702 |
1 | J:270427 Yabut OR, Fernandez G, Huynh T, Yoon K, Pleasure SJ, Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis. Cell Rep. 2015 Sep 29;12(12):2021-34 |
1 | J:147307 Yokota Y, Kim WY, Chen Y, Wang X, Stanco A, Komuro Y, Snider W, Anton ES, The adenomatous polyposis coli protein is an essential regulator of radial glial polarity and construction of the cerebral cortex. Neuron. 2009 Jan 15;61(1):42-56 |
1 | J:281878 Yook C, Kim K, Kim D, Kang H, Kim SG, Kim E, Kim SY, A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice. Front Mol Neurosci. 2019;12:241 |
1 | J:328995 Zhang SF, Dai SK, Du HZ, Wang H, Li XG, Tang Y, Liu CM, The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis. Stem Cell Reports. 2022 Sep 13;17(9):2064-2080 |
1 | J:287752 Zhang W, Ma L, Yang M, Shao Q, Xu J, Lu Z, Zhao Z, Chen R, Chai Y, Chen JF, Cerebral organoid and mouse models reveal a RAB39b-PI3K-mTOR pathway-dependent dysregulation of cortical development leading to macrocephaly/autism phenotypes. Genes Dev. 2020 Apr 1;34(7-8):580-597 |
1 | J:297167 Zhao YF, He XX, Song ZF, Guo Y, Zhang YN, Yu HL, He ZX, Xiong WC, Guo W, Zhu XJ, Human antigen R-regulated mRNA metabolism promotes the cell motility of migrating mouse neurons. Development. 2020 Mar 16;147(6):dev183509 |
Tbx1 T-box 1 (Synonyms: nmf219) | |
Results | Reference |
1* | J:166613 Cao H, Florez S, Amen M, Huynh T, Skobe Z, Baldini A, Amendt BA, Tbx1 regulates progenitor cell proliferation in the dental epithelium by modulating Pitx2 activation of p21. Dev Biol. 2010 Nov 15;347(2):289-300 |
1 | J:304609 Caprio C, Lania G, Bilio M, Ferrentino R, Chen L, Baldini A, EZH2 is required for parathyroid and thymic development through differentiation of the third pharyngeal pouch endoderm. Dis Model Mech. 2021 Feb 19;:dmm.046789 |
1* | J:149254 Caton J, Luder HU, Zoupa M, Bradman M, Bluteau G, Tucker AS, Klein O, Mitsiadis TA, Enamel-free teeth: Tbx1 deletion affects amelogenesis in rodent incisors. Dev Biol. 2009 Apr 15;328(2):493-505 |
2 | J:159824 Chen L, Mupo A, Huynh T, Cioffi S, Woods M, Jin C, McKeehan W, Thompson-Snipes L, Baldini A, Illingworth E, Tbx1 regulates Vegfr3 and is required for lymphatic vessel development. J Cell Biol. 2010 May 3;189(3):417-24 |
1 | J:143603 Esibizione D, Cui CY, Schlessinger D, Candidate EDA targets revealed by expression profiling of primary keratinocytes from Tabby mutant mice. Gene. 2008 Dec 31;427(1-2):42-6 |
1 | J:217210 Funato N, Nakamura M, Richardson JA, Srivastava D, Yanagisawa H, Loss of Tbx1 induces bone phenotypes similar to cleidocranial dysplasia. Hum Mol Genet. 2015 Jan 15;24(2):424-35 |
1 | J:347133 Funato N, Srivastava D, Shibata S, Yanagisawa H, TBX1 Regulates Chondrocyte Maturation in the Spheno-occipital Synchondrosis. J Dent Res. 2020 Sep;99(10):1182-1191 |
1 | J:187316 Kyrylkova K, Kyryachenko S, Biehs B, Klein O, Kioussi C, Leid M, BCL11B regulates epithelial proliferation and asymmetric development of the mouse mandibular incisor. PLoS One. 2012;7(5):e37670 |
1 | J:164590 Mitsiadis TA, Graf D, Luder H, Gridley T, Bluteau G, BMPs and FGFs target Notch signalling via jagged 2 to regulate tooth morphogenesis and cytodifferentiation. Development. 2010 Sep;137(18):3025-35 |
1 | J:308790 Sweat M, Sweat Y, Yu W, Su D, Leonard RJ, Eliason SL, Amendt BA, The miR-200 family is required for ectodermal organ development through the regulation of the epithelial stem cell niche. Stem Cells. 2021 Jun;39(6):761-775 |
1 | J:128008 Xu H, Chen L, Baldini A, In vivo genetic ablation of the periotic mesoderm affects cell proliferation survival and differentiation in the cochlea. Dev Biol. 2007 Oct 15;310(2):329-40 |
1 | J:354246 Zhu S, Huo S, Wang Z, Huang C, Li C, Song H, Yang X, He R, Ding C, Qiu M, Zhu XJ, Follistatin controls the number of murine teeth by limiting TGF-beta signaling. iScience. 2024 Sep 20;27(9):110785 |
Tbx2 T-box 2 | |
Results | Reference |
2* | J:272619 Aydogdu N, Rudat C, Trowe MO, Kaiser M, Ludtke TH, Taketo MM, Christoffels VM, Moon A, Kispert A, TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1* | J:198654 Saadi I, Das P, Zhao M, Raj L, Ruspita I, Xia Y, Papaioannou VE, Bei M, Msx1 and Tbx2 antagonistically regulate Bmp4 expression during the bud-to-cap stage transition in tooth development. Development. 2013 Jul;140(13):2697-702 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
2 | J:340973 Wojahn I, Ludtke TH, Christoffels VM, Trowe MO, Kispert A, TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung. Respir Res. 2019 Dec 23;20(1):292 |
Tbx3 T-box 3 (Synonyms: D5Ertd189e) | |
Results | Reference |
2* | J:272619 Aydogdu N, Rudat C, Trowe MO, Kaiser M, Ludtke TH, Taketo MM, Christoffels VM, Moon A, Kispert A, TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827 |
1 | J:149014 Bakker ML, Boukens BJ, Mommersteeg MT, Brons JF, Wakker V, Moorman AF, Christoffels VM, Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system. Circ Res. 2008 Jun 6;102(11):1340-9 |
1 | J:221075 Dai M, Wang Y, Fang L, Irwin DM, Zhu T, Zhang J, Zhang S, Wang Z, Differential expression of Meis2, Mab21l2 and Tbx3 during limb development associated with diversification of limb morphology in mammals. PLoS One. 2014;9(8):e106100 |
1 | J:126770 Hodge LK, Klassen MP, Han BX, Yiu G, Hurrell J, Howell A, Rousseau G, Lemaigre F, Tessier-Lavigne M, Wang F, Retrograde BMP signaling regulates trigeminal sensory neuron identities and the formation of precise face maps. Neuron. 2007 Aug 16;55(4):572-86 |
1 | J:204126 Liang X, Wang G, Lin L, Lowe J, Zhang Q, Bu L, Chen Y, Chen J, Sun Y, Evans SM, HCN4 dynamically marks the first heart field and conduction system precursors. Circ Res. 2013 Aug 2;113(4):399-407 |
1 | J:317604 Liu F, Lu MM, Patel NN, Schillinger KJ, Wang T, Patel VV, GATA-Binding Factor 6 Contributes to Atrioventricular Node Development and Function. Circ Cardiovasc Genet. 2015 Apr;8(2):284-93 |
2 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:231738 Reed-Geaghan EG, Wright MC, See LA, Adelman PC, Lee KH, Koerber HR, Maricich SM, Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes. J Neurosci. 2016 Apr 13;36(15):4362-76 |
1 | J:134487 Suzuki A, Sekiya S, Buscher D, Izpisua Belmonte JC, Taniguchi H, Tbx3 controls the fate of hepatic progenitor cells in liver development by suppressing p19ARF expression. Development. 2008 May;135(9):1589-95 |
1 | J:340973 Wojahn I, Ludtke TH, Christoffels VM, Trowe MO, Kispert A, TBX2-positive cells represent a multi-potent mesenchymal progenitor pool in the developing lung. Respir Res. 2019 Dec 23;20(1):292 |
1 | J:348286 Zhang Z, Wu Y, Fu J, Yu X, Su Y, Jia S, Cheng H, Shen Y, He X, Ren K, Zheng X, Guan H, Rao F, Zhao L, Proteostatic reactivation of the developmental transcription factor TBX3 drives BRAF/MAPK-mediated tumorigenesis. Nat Commun. 2024 May 15;15(1):4108 |
Tbx3os1 T-box 3, opposite strand 1 (Synonyms: Gm2301) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Tbx4 T-box 4 | |
Results | Reference |
1 | J:268349 Kim HT, Yin W, Jin YJ, Panza P, Gunawan F, Grohmann B, Buettner C, Sokol AM, Preussner J, Guenther S, Kostin S, Ruppert C, Bhagwat AM, Ma X, Graumann J, Looso M, Guenther A, Adelstein RS, Offermanns S, Stainier DYR, Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease. Nat Commun. 2018 Nov 2;9(1):4600 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:139169 Menke DB, Guenther C, Kingsley DM, Dual hindlimb control elements in the Tbx4 gene and region-specific control of bone size in vertebrate limbs. Development. 2008 Aug;135(15):2543-53 |
1* | J:177135 Naiche LA, Arora R, Kania A, Lewandoski M, Papaioannou VE, Identity and fate of Tbx4-expressing cells reveal developmental cell fate decisions in the allantois, limb, and external genitalia. Dev Dyn. 2011 Oct;240(10):2290-300 |
Tbx5 T-box 5 | |
Results | Reference |
1 | J:149014 Bakker ML, Boukens BJ, Mommersteeg MT, Brons JF, Wakker V, Moorman AF, Christoffels VM, Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system. Circ Res. 2008 Jun 6;102(11):1340-9 |
1* | J:74241 Barbieri AM, Broccoli V, Bovolenta P, Alfano G, Marchitiello A, Mocchetti C, Crippa L, Bulfone A, Marigo V, Ballabio A, Banfi S, Vax2 inactivation in mouse determines alteration of the eye dorsal-ventral axis, misrouting of the optic fibres and eye coloboma. Development. 2002 Feb;129(3):805-13 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
1 | J:119145 Franco D, Meilhac SM, Christoffels VM, Kispert A, Buckingham M, Kelly RG, Left and right ventricular contributions to the formation of the interventricular septum in the mouse heart. Dev Biol. 2006 Jun 15;294(2):366-75 |
1* | J:329049 Galdos FX, Xu S, Goodyer WR, Duan L, Huang YV, Lee S, Zhu H, Lee C, Wei N, Lee D, Wu SM, devCellPy is a machine learning-enabled pipeline for automated annotation of complex multilayered single-cell transcriptomic data. Nat Commun. 2022 Sep 7;13(1):5271 |
1 | J:224301 Harris JP, Bhakta M, Bezprozvannaya S, Wang L, Lubczyk C, Olson EN, Munshi NV, MyoR modulates cardiac conduction by repressing Gata4. Mol Cell Biol. 2015 Feb;35(4):649-61 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
Tbx15 T-box 15 (Synonyms: de, Tbx14, Tbx8) | |
Results | Reference |
1* | J:49066 Agulnik SI, Papaioannou VE, Silver LM, Cloning, mapping, and expression analysis of TBX15, a new member of the T-Box gene family. Genomics. 1998 Jul 1;51(1):68-75 |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
2* | J:96466 Singh MK, Petry M, Haenig B, Lescher B, Leitges M, Kispert A, The T-box transcription factor Tbx15 is required for skeletal development. Mech Dev. 2005 Feb;122(2):131-44 |
Tbx18 T-box18 (Synonyms: 2810012F10Rik, 2810404D13Rik) | |
Results | Reference |
2 | J:106499 Airik R, Bussen M, Singh MK, Petry M, Kispert A, Tbx18 regulates the development of the ureteral mesenchyme. J Clin Invest. 2006 Mar;116(3):663-74 |
1 | J:214677 Bohnenpoll T, Trowe MO, Wojahn I, Taketo MM, Petry M, Kispert A, Canonical Wnt signaling regulates the proliferative expansion and differentiation of fibrocytes in the murine inner ear. Dev Biol. 2014 Jul 1;391(1):54-65 |
2 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1* | J:147421 Christoffels VM, Grieskamp T, Norden J, Mommersteeg MT, Rudat C, Kispert A, Tbx18 and the fate of epicardial progenitors. Nature. 2009 Apr 16;458(7240):E8-9; discussion E9-10 |
1 | J:119145 Franco D, Meilhac SM, Christoffels VM, Kispert A, Buckingham M, Kelly RG, Left and right ventricular contributions to the formation of the interventricular septum in the mouse heart. Dev Biol. 2006 Jun 15;294(2):366-75 |
1* | J:308556 Goss G, Rognoni E, Salameti V, Watt FM, Distinct Fibroblast Lineages Give Rise to NG2+ Pericyte Populations in Mouse Skin Development and Repair. Front Cell Dev Biol. 2021;9:675080 |
2 | J:250657 Greulich F, Trowe MO, Leffler A, Stoetzer C, Farin HF, Kispert A, Misexpression of Tbx18 in cardiac chambers of fetal mice interferes with chamber-specific developmental programs but does not induce a pacemaker-like gene signature. J Mol Cell Cardiol. 2016 Aug;97:140-9 |
1 | J:196480 Grisanti L, Clavel C, Cai X, Rezza A, Tsai SY, Sennett R, Mumau M, Cai CL, Rendl M, Tbx18 targets dermal condensates for labeling, isolation, and gene ablation during embryonic hair follicle formation. J Invest Dermatol. 2013 Feb;133(2):344-53 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
2* | J:211545 Pu D, Du JL, Zhang J, Li XQ, Weng MJ, Liu YJ, Gao LZ, Xia S, Chen YQ, She Q, An economical and practical method for whole-mount in situ hybridization for mouse embryos and organs. Biotech Histochem. 2013 Jan;88(1):27-37 |
Tbx19 T-box 19 (Synonyms: D1Ertd754e, Tpit) | |
Results | Reference |
1 | J:188254 Budry L, Balsalobre A, Gauthier Y, Khetchoumian K, L'honore A, Vallette S, Brue T, Figarella-Branger D, Meij B, Drouin J, The selector gene Pax7 dictates alternate pituitary cell fates through its pioneer action on chromatin remodeling. Genes Dev. 2012 Oct 15;26(20):2299-310 |
1 | J:233385 Castinetti F, Brinkmeier ML, Mortensen AH, Vella KR, Gergics P, Brue T, Hollenberg AN, Gan L, Camper SA, ISL1 Is Necessary for Maximal Thyrotrope Response to Hypothyroidism. Mol Endocrinol. 2015 Oct;29(10):1510-21 |
1 | J:264143 Cheung L, Le Tissier P, Goldsmith SG, Treier M, Lovell-Badge R, Rizzoti K, NOTCH activity differentially affects alternative cell fate acquisition and maintenance. Elife. 2018 Mar 26;7:e33318 |
1 | J:176609 Goldberg LB, Aujla PK, Raetzman LT, Persistent expression of activated Notch inhibits corticotrope and melanotrope differentiation and results in dysfunction of the HPA axis. Dev Biol. 2011 Oct 1;358(1):23-32 |
1 | J:235668 Goldsmith S, Lovell-Badge R, Rizzoti K, SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitary. Development. 2016 Jul 1;143(13):2376-88 |
1 | J:241998 Haston S, Pozzi S, Carreno G, Manshaei S, Panousopoulos L, Gonzalez-Meljem JM, Apps JR, Virasami A, Thavaraj S, Gutteridge A, Forshew T, Marais R, Brandner S, Jacques TS, Andoniadou CL, Martinez-Barbera JP, MAPK pathway control of stem cell proliferation and differentiation in the embryonic pituitary provides insights into the pathogenesis of papillary craniopharyngioma. Development. 2017 Jun 15;144(12):2141-2152 |
1 | J:89087 Lamolet B, Poulin G, Chu K, Guillemot F, Tsai MJ, Drouin J, Tpit-independent function of NeuroD1(BETA2) in pituitary corticotroph differentiation. Mol Endocrinol. 2004 Apr;18(4):995-1003 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Tbx20 T-box 20 (Synonyms: 9430010M06Rik, Tbx12) | |
Results | Reference |
1 | J:149014 Bakker ML, Boukens BJ, Mommersteeg MT, Brons JF, Wakker V, Moorman AF, Christoffels VM, Transcription factor Tbx3 is required for the specification of the atrioventricular conduction system. Circ Res. 2008 Jun 6;102(11):1340-9 |
1 | J:110808 Dufour HD, Chettouh Z, Deyts C, de Rosa R, Goridis C, Joly JS, Brunet JF, Precraniate origin of cranial motoneurons. Proc Natl Acad Sci U S A. 2006 Jun 6;103(23):8727-32 |
1 | J:237201 Espinosa-Medina I, Saha O, Boismoreau F, Chettouh Z, Rossi F, Richardson WD, Brunet JF, The sacral autonomic outflow is sympathetic. Science. 2016 Nov 18;354(6314):893-897 |
1 | J:119145 Franco D, Meilhac SM, Christoffels VM, Kispert A, Buckingham M, Kelly RG, Left and right ventricular contributions to the formation of the interventricular septum in the mouse heart. Dev Biol. 2006 Jun 15;294(2):366-75 |
1 | J:357469 Sivori M, Dempsey B, Chettouh Z, Boismoreau F, Ayerdi M, et al., The pelvic organs receive no parasympathetic innervation. Elife. 2024;15 |
1 | J:101739 Takeuchi JK, Mileikovskaia M, Koshiba-Takeuchi K, Heidt AB, Mori AD, Arruda EP, Gertsenstein M, Georges R, Davidson L, Mo R, Hui CC, Henkelman RM, Nemer M, Black BL, Nagy A, Bruneau BG, Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development. Development. 2005 May;132(10):2463-74 |
Tbx21 T-box 21 (Synonyms: T-bet, Tbet, Tblym, TBT1) | |
Results | Reference |
1* | J:78160 Faedo A, Ficara F, Ghiani M, Aiuti A, Rubenstein JL, Bulfone A, Developmental expression of the T-box transcription factor T-bet/Tbx21 during mouse embryogenesis. Mech Dev. 2002 Aug;116(1-2):157-60 |
Tbx22 T-box 22 (Synonyms: D230020M15Rik) | |
Results | Reference |
1* | J:79619 Braybrook C, Lisgo S, Doudney K, Henderson D, Marcano AC, Strachan T, Patton MA, Villard L, Moore GE, Stanier P, Lindsay S, Craniofacial expression of human and murine TBX22 correlates with the cleft palate and ankyloglossia phenotype observed in CPX patients. Hum Mol Genet. 2002 Oct 15;11(22):2793-804 |
Tcap titin-cap (Synonyms: Telethonin) | |
Results | Reference |
1* | J:325107 Cao X, Yan Y, Luo X, Yang X, Cui H, Yang Y, Li H, Analyses of the circadian clock genes expression in whole embryos and maternal major tissues of mice. J Mol Histol. 2022 Apr;53(2):473-482 |
Tcf3 transcription factor 3 (Synonyms: A1, ALF2, bHLHb21, E12, E2A, E47, Pan1, Pan2, Tcfe2a) | |
Results | Reference |
1* | J:331303 Kantzer CG, Yang W, Grommisch D, Patikl KV, Mak KH, Shirokova V, Genander M, ID1 and CEBPA coordinate epidermal progenitor cell differentiation. Development. 2022 Nov;149(22) |
Tcf4 transcription factor 4 (Synonyms: 5730422P05Rik, ASP-I2, bHLHb19, E2-2, E2.2, ITF-2, ITF-2b, ME2, MITF-2A, MITF-2B, SEF-2, SEF2-1, TFE) | |
Results | Reference |
1* | J:331303 Kantzer CG, Yang W, Grommisch D, Patikl KV, Mak KH, Shirokova V, Genander M, ID1 and CEBPA coordinate epidermal progenitor cell differentiation. Development. 2022 Nov;149(22) |
1 | J:308040 Kim H, Berens NC, Ochandarena NE, Philpot BD, Region and Cell Type Distribution of TCF4 in the Postnatal Mouse Brain. Front Neuroanat. 2020;14:42 |
2 | J:306233 Mesman S, Bakker R, Smidt MP, Tcf4 is required for correct brain development during embryogenesis. Mol Cell Neurosci. 2020 Jul;106:103502 |
1* | J:359452 Pang Y, Ruan X, Liu W, Hou L, Yin B, Shu P, Peng X, MicroRNA-495 Modulates Neuronal Layer Fate Determination by Targeting Tcf4. Int J Biol Sci. 2024;20(15):6207-6221 |
1 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
1 | J:278474 Zhu XJ, Liu Y, Dai ZM, Zhang X, Yang X, Li Y, Qiu M, Fu J, Hsu W, Chen Y, Zhang Z, BMP-FGF signaling axis mediates Wnt-induced epidermal stratification in developing mammalian skin. PLoS Genet. 2014 Oct;10(10):e1004687 |
Tcf7 transcription factor 7, T cell specific (Synonyms: T cell factor-1, T-cell factor 1, Tcf1, TCF-1) | |
Results | Reference |
1 | J:127546 Brinkmeier ML, Potok MA, Davis SW, Camper SA, TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors. Dev Biol. 2007 Nov 15;311(2):396-407 |
1 | J:355647 Bugacov H, Der B, Briantseva BM, Guo Q, Kim S, Lindstrom NO, McMahon AP, Dose-dependent responses to canonical Wnt transcriptional complexes in the regulation of mammalian nephron progenitors. Development. 2024 Sep 15;151(18) |
1 | J:188176 Caparros-Martin JA, Valencia M, Reytor E, Pacheco M, Fernandez M, Perez-Aytes A, Gean E, Lapunzina P, Peters H, Goodship JA, Ruiz-Perez VL, The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia. Hum Mol Genet. 2013 Jan 1;22(1):124-39 |
1 | J:98430 Glass DA 2nd, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G, Canonical wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell. 2005 May;8(5):751-64 |
1 | J:98426 Hill TP, Spater D, Taketo MM, Birchmeier W, Hartmann C, Canonical Wnt/beta-Catenin Signaling Prevents Osteoblasts from Differentiating into Chondrocytes. Dev Cell. 2005 May;8(5):727-38 |
1 | J:197885 Nagalski A, Irimia M, Szewczyk L, Ferran JL, Misztal K, Kuznicki J, Wisniewska MB, Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain. Brain Struct Funct. 2013 Nov;218(6):1531-49 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Tcf7l1 transcription factor 7 like 1 (T cell specific, HMG box) (Synonyms: Tcf3) | |
Results | Reference |
1 | J:355647 Bugacov H, Der B, Briantseva BM, Guo Q, Kim S, Lindstrom NO, McMahon AP, Dose-dependent responses to canonical Wnt transcriptional complexes in the regulation of mammalian nephron progenitors. Development. 2024 Sep 15;151(18) |
1 | J:98430 Glass DA 2nd, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G, Canonical wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell. 2005 May;8(5):751-64 |
1* | J:45934 Korinek V, Barker N, Willert K, Molenaar M, Roose J, Wagenaar G, Markman M, Lamers W, Destree O, Clevers H, Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse. Mol Cell Biol. 1998 Mar;18(3):1248-56 |
1 | J:197885 Nagalski A, Irimia M, Szewczyk L, Ferran JL, Misztal K, Kuznicki J, Wisniewska MB, Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain. Brain Struct Funct. 2013 Nov;218(6):1531-49 |
1* | J:73292 Ridanpaa M, Fodde R, Kielman M, Dynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structures. Mech Dev. 2001 Dec;109(2):173-81 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Tcf7l2 transcription factor 7 like 2, T cell specific, HMG box (Synonyms: mTcf-4B, mTcf-4E, Tcf-4, Tcf4, TCF4B, TCF4E) | |
Results | Reference |
1 | J:170088 Angus-Hill ML, Elbert KM, Hidalgo J, Capecchi MR, T-cell factor 4 functions as a tumor suppressor whose disruption modulates colon cell proliferation and tumorigenesis. Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):4914-9 |
1 | J:127546 Brinkmeier ML, Potok MA, Davis SW, Camper SA, TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors. Dev Biol. 2007 Nov 15;311(2):396-407 |
1 | J:355647 Bugacov H, Der B, Briantseva BM, Guo Q, Kim S, Lindstrom NO, McMahon AP, Dose-dependent responses to canonical Wnt transcriptional complexes in the regulation of mammalian nephron progenitors. Development. 2024 Sep 15;151(18) |
1* | J:50943 Cho EA, Dressler GR, TCF-4 binds beta-catenin and is expressed in distinct regions of the embryonic brain and limbs. Mech Dev. 1998 Sep;77(1):9-18 |
1 | J:98430 Glass DA 2nd, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G, Canonical wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell. 2005 May;8(5):751-64 |
1 | J:267950 Holzman MA, Bergmann JM, Feldman M, Landry-Truchon K, Jeannotte L, Mansfield JH, HOXA5 protein expression and genetic fate mapping show lineage restriction in the developing musculoskeletal system. Int J Dev Biol. 2018;62(11-12):785-796 |
1 | J:164807 Joo JH, Taxter TJ, Munguba GC, Kim YH, Dhaduvai K, Dunn NW, Degan WJ, Oh SP, Sugrue SP, Pinin modulates expression of an intestinal homeobox gene, Cdx2, and plays an essential role for small intestinal morphogenesis. Dev Biol. 2010 Sep 15;345(2):191-203 |
1 | J:48968 Korinek V, Barker N, Moerer P, van Donselaar E, Huls G, Peters PJ, Clevers H, Depletion of epithelial stem-cell compartments in the small intestine of mice lacking Tcf-4. Nat Genet. 1998 Aug;19(4):379-83 |
1* | J:45934 Korinek V, Barker N, Willert K, Molenaar M, Roose J, Wagenaar G, Markman M, Lamers W, Destree O, Clevers H, Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse. Mol Cell Biol. 1998 Mar;18(3):1248-56 |
1 | J:220322 Kutchuk L, Laitala A, Soueid-Bomgarten S, Shentzer P, Rosendahl AH, Eilot S, Grossman M, Sagi I, Sormunen R, Myllyharju J, Maki JM, Hasson P, Muscle composition is regulated by a Lox-TGFbeta feedback loop. Development. 2015 Mar 1;142(5):983-93 |
1* | J:316578 Lade A, Ranganathan S, Luo J, Monga SP, Calpain induces N-terminal truncation of beta-catenin in normal murine liver development: diagnostic implications in hepatoblastomas. J Biol Chem. 2012 Jun 29;287(27):22789-98 |
1 | J:231793 Merrell AJ, Ellis BJ, Fox ZD, Lawson JA, Weiss JA, Kardon G, Muscle connective tissue controls development of the diaphragm and is a source of congenital diaphragmatic hernias. Nat Genet. 2015 May;47(5):496-504 |
1 | J:197885 Nagalski A, Irimia M, Szewczyk L, Ferran JL, Misztal K, Kuznicki J, Wisniewska MB, Postnatal isoform switch and protein localization of LEF1 and TCF7L2 transcription factors in cortical, thalamic, and mesencephalic regions of the adult mouse brain. Brain Struct Funct. 2013 Nov;218(6):1531-49 |
1* | J:336866 Puelles L, Hidalgo-Sanchez M, The Midbrain Preisthmus: A Poorly Known Effect of the Isthmic Organizer. Int J Mol Sci. 2023 Jun 5;24(11) |
1* | J:73292 Ridanpaa M, Fodde R, Kielman M, Dynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structures. Mech Dev. 2001 Dec;109(2):173-81 |
1* | J:287411 Tran HN, Park W, Seong S, Jeong JE, Nguyen QH, Yoon J, Baek K, Jeong Y, Tcf7l2 transcription factor is required for the maintenance, but not the initial specification, of the neurotransmitter identity in the caudal thalamus. Dev Dyn. 2020 May;249(5):646-655 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
1 | J:152576 Ye F, Chen Y, Hoang T, Montgomery RL, Zhao XH, Bu H, Hu T, Taketo MM, van Es JH, Clevers H, Hsieh J, Bassel-Duby R, Olson EN, Lu QR, HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction. Nat Neurosci. 2009 Jul;12(7):829-38 |
Tcf12 transcription factor 12 (Synonyms: ALF1, bHLHb20, HEB, HEBAlt, HTF-4, HTF4, ME1, REB) | |
Results | Reference |
1* | J:331303 Kantzer CG, Yang W, Grommisch D, Patikl KV, Mak KH, Shirokova V, Genander M, ID1 and CEBPA coordinate epidermal progenitor cell differentiation. Development. 2022 Nov;149(22) |
1 | J:60116 Uittenbogaard M, Chiaramello A, Expression of the basic Helix-Loop-Helix ME1 E-protein during development and aging of the murine cerebellum. Neurosci Lett. 1999 Oct 29;274(3):191-4 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Tcf15 transcription factor 15 (Synonyms: bHLH-EC2, Meso1, paraxis) | |
Results | Reference |
1* | J:26515 Blanar MA, Crossley PH, Peters KG, Steingrimsson E, Copeland NG, Jenkins NA, Martin GR, Rutter WJ, Meso1, a basic-helix-loop-helix protein involved in mammalian presomitic mesoderm development. Proc Natl Acad Sci U S A. 1995 Jun 20;92(13):5870-4 |
Tcf19 transcription factor 19 (Synonyms: 5730403J10Rik) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Tcf21 transcription factor 21 (Synonyms: bHLHa23, capsulin, epc, epicardin, Pod-1, Pod1, podocyte-expressed 1) | |
Results | Reference |
1 | J:185552 Acharya A, Baek ST, Huang G, Eskiocak B, Goetsch S, Sung CY, Banfi S, Sauer MF, Olsen GS, Duffield JS, Olson EN, Tallquist MD, The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors. Development. 2012 Jun;139(12):2139-49 |
1 | J:362029 Anjum H, Smith JP, Martini AG, Yacu GS, Medrano S, Gomez RA, Sequeira-Lopez MLS, Quaggin SE, Finer G, Tcf21 as a founder transcription factor in specifying Foxd1 cells to the juxtaglomerular cell lineage. Am J Physiol Renal Physiol. 2025 Jan 1;328(1):F121-F130 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1 | J:291050 Ide S, Finer G, Maezawa Y, Onay T, Souma T, Scott R, Ide K, Akimoto Y, Li C, Ye M, Zhao X, Baba Y, Minamizuka T, Jin J, Takemoto M, Yokote K, Quaggin SE, Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development. J Am Soc Nephrol. 2018 Dec;29(12):2795-2808 |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
1 | J:275480 Park J, Ivey MJ, Deana Y, Riggsbee KL, Sorensen E, Schwabl V, Sjoberg C, Hjertberg T, Park GY, Swonger JM, Rosengreen T, Morty RE, Ahlbrecht K, Tallquist MD, The Tcf21 lineage constitutes the lung lipofibroblast population. Am J Physiol Lung Cell Mol Physiol. 2019 May 1;316(5):L872-L885 |
2* | J:47105 Quaggin SE, Vanden Heuvel GB, Igarash P, Pod-1, a mesoderm-specific basic-helix-loop-helix protein expressed in mesenchymal and glomerular epithelial cells in the developing kidney. Mech Dev. 1998 Feb;71(1-2):37-48 |
Tchp trichoplein, keratin filament binding (Synonyms: A930031F18Rik) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Tcn2 transcobalamin 2 (Synonyms: Tcn-2) | |
Results | Reference |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Tcra T cell receptor alpha chain (Synonyms: Tcr alpha, Tcralpha) | |
Results | Reference |
1* | J:15545 Boehm T, Spillantini MG, Sofroniew MV, Surani MA, Rabbitts TH, Developmentally regulated and tissue specific expression of mRNAs encoding the two alternative forms of the LIM domain oncogene rhombotin: evidence for thymus expression. Oncogene. 1991 May;6(5):695-703 |
Tcrd T cell receptor delta chain (Synonyms: Tcr delta, Tcrdelta) | |
Results | Reference |
1* | J:15545 Boehm T, Spillantini MG, Sofroniew MV, Surani MA, Rabbitts TH, Developmentally regulated and tissue specific expression of mRNAs encoding the two alternative forms of the LIM domain oncogene rhombotin: evidence for thymus expression. Oncogene. 1991 May;6(5):695-703 |
Tcrd-J T cell receptor delta, joining region | |
Results | Reference |
1 | J:43089 Wilbert OM, Weber-Arden J, Kabelitz D, Arden B, TCR-delta gene rearrangement and selection during fetal thymocyte development. J Immunol. 1997 Oct 1;159(7):3338-46 |
Tcrd-V7 T cell receptor delta, variable 7 | |
Results | Reference |
1 | J:43089 Wilbert OM, Weber-Arden J, Kabelitz D, Arden B, TCR-delta gene rearrangement and selection during fetal thymocyte development. J Immunol. 1997 Oct 1;159(7):3338-46 |
Tdg thymine DNA glycosylase (Synonyms: E130317C12Rik, Jza1) | |
Results | Reference |
1* | J:50138 Niederreither K, Harbers M, Chambon P, Dolle P, Expression of T:G mismatch-specific thymidine-DNA glycosylase and DNA methyl transferase genes during development and tumorigenesis. Oncogene. 1998 Sep 24;17(12):1577-85 |
Tdo2 tryptophan 2,3-dioxygenase (Synonyms: chky, TDO, TO) | |
Results | Reference |
1* | J:272586 Suzuki T, Kikuguchi C, Nishijima S, Nagashima T, Takahashi A, Okada M, Yamamoto T, Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. Development. 2019 Feb 15;146(4):dev168146 |
Tdpoz2 TD and POZ domain containing 2 | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Tdrd1 tudor domain containing 1 (Synonyms: MTR-1) | |
Results | Reference |
1 | J:184034 De Fazio S, Bartonicek N, Di Giacomo M, Abreu-Goodger C, Sankar A, Funaya C, Antony C, Moreira PN, Enright AJ, O'Carroll D, The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements. Nature. 2011 Dec 8;480(7376):259-63 |
1* | J:159518 Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Takamatsu K, Chuma S, Kojima-Kita K, Shiromoto Y, Asada N, Toyoda A, Fujiyama A, Totoki Y, Shibata T, Kimura T, Nakatsuji N, Noce T, Sasaki H, Nakano T, MVH in piRNA processing and gene silencing of retrotransposons. Genes Dev. 2010 May;24(9):887-92 |
2* | J:277128 Shiromoto Y, Kuramochi-Miyagawa S, Nagamori I, Chuma S, Arakawa T, Nishimura T, Hasuwa H, Tachibana T, Ikawa M, Nakano T, GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice. Biol Reprod. 2019 Jul 1;101(1):248-256 |
1 | J:306454 Tan K, Kim ME, Song HW, Skarbrevik D, Babajanian E, Bedrosian TA, Gage FH, Wilkinson MF, The Rhox gene cluster suppresses germline LINE1 transposition. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2024785118 |
1 | J:169934 Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A, Hoki Y, Fujiyama A, Shibata T, Sado T, Noce T, Nakano T, Nakatsuji N, Lin H, Sasaki H, MITOPLD Is a Mitochondrial Protein Essential for Nuage Formation and piRNA Biogenesis in the Mouse Germline. Dev Cell. 2011 Mar 15;20(3):364-75 |
1 | J:170319 Yabuta Y, Ohta H, Abe T, Kurimoto K, Chuma S, Saitou M, TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice. J Cell Biol. 2011 Mar 7;192(5):781-95 |
Tdrd5 tudor domain containing 5 | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
2 | J:170319 Yabuta Y, Ohta H, Abe T, Kurimoto K, Chuma S, Saitou M, TDRD5 is required for retrotransposon silencing, chromatoid body assembly, and spermiogenesis in mice. J Cell Biol. 2011 Mar 7;192(5):781-95 |
Tdrd9 tudor domain containing 9 (Synonyms: 4930441E05Rik) | |
Results | Reference |
1 | J:184034 De Fazio S, Bartonicek N, Di Giacomo M, Abreu-Goodger C, Sankar A, Funaya C, Antony C, Moreira PN, Enright AJ, O'Carroll D, The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements. Nature. 2011 Dec 8;480(7376):259-63 |
1* | J:159518 Kuramochi-Miyagawa S, Watanabe T, Gotoh K, Takamatsu K, Chuma S, Kojima-Kita K, Shiromoto Y, Asada N, Toyoda A, Fujiyama A, Totoki Y, Shibata T, Kimura T, Nakatsuji N, Noce T, Sasaki H, Nakano T, MVH in piRNA processing and gene silencing of retrotransposons. Genes Dev. 2010 May;24(9):887-92 |
1 | J:156018 Shoji M, Tanaka T, Hosokawa M, Reuter M, Stark A, Kato Y, Kondoh G, Okawa K, Chujo T, Suzuki T, Hata K, Martin SL, Noce T, Kuramochi-Miyagawa S, Nakano T, Sasaki H, Pillai RS, Nakatsuji N, Chuma S, The TDRD9-MIWI2 complex is essential for piRNA-mediated retrotransposon silencing in the mouse male germline. Dev Cell. 2009 Dec;17(6):775-87 |
1 | J:243488 Wenda JM, Homolka D, Yang Z, Spinelli P, Sachidanandam R, Pandey RR, Pillai RS, Distinct Roles of RNA Helicases MVH and TDRD9 in PIWI Slicing-Triggered Mammalian piRNA Biogenesis and Function. Dev Cell. 2017 Jun 19;41(6):623-637.e9 |
Tead1 TEA domain family member 1 (Synonyms: 2610024B07Rik, B230114H05Rik, Gtrgeo5, mTEF-1, Tcf13, TEAD-1, TEF-1) | |
Results | Reference |
1* | J:35437 Jacquemin P, Hwang JJ, Martial JA, Dolle P, Davidson I, A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain. J Biol Chem. 1996 Sep 6;271(36):21775-85 |
2* | J:306471 Niki Y, Kobayashi Y, Moriyama K, Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth. Gene Expr Patterns. 2021 Jun;40:119182 |
1* | J:360369 Pelenyi A, Atterton C, Jones J, Currey L, Al-Khalily M, Wright L, Kurniawan ND, Thor S, Piper M, Expression of the Hippo pathway effector, TEAD1, within the developing murine forebrain. Gene Expr Patterns. 2024 Dec;54:119384 |
Tead2 TEA domain family member 2 (Synonyms: Etdf, TEAD-2, TEF-4) | |
Results | Reference |
1* | J:35437 Jacquemin P, Hwang JJ, Martial JA, Dolle P, Davidson I, A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain. J Biol Chem. 1996 Sep 6;271(36):21775-85 |
1* | J:306471 Niki Y, Kobayashi Y, Moriyama K, Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth. Gene Expr Patterns. 2021 Jun;40:119182 |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
Tead3 TEA domain family member 3 (Synonyms: DTEF-1, ETFR-1, Tcf13r2, TEAD-3, TEF-5) | |
Results | Reference |
1* | J:306471 Niki Y, Kobayashi Y, Moriyama K, Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth. Gene Expr Patterns. 2021 Jun;40:119182 |
Tead4 TEA domain family member 4 (Synonyms: Etfr2, ETFR-2a, Rtef1, Tcf13r1, TEAD-4, Tef3, TEF-3, Tefr, Tefr1a) | |
Results | Reference |
1* | J:306471 Niki Y, Kobayashi Y, Moriyama K, Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth. Gene Expr Patterns. 2021 Jun;40:119182 |
Tecta tectorin alpha (Synonyms: [a]-tectorin, Tctna) | |
Results | Reference |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
3 | J:245765 Goodyear RJ, Lu X, Deans MR, Richardson GP, A tectorin-based matrix and planar cell polarity genes are required for normal collagen-fibril orientation in the developing tectorial membrane. Development. 2017 Nov 01;144(21):3978-3989 |
Tectb tectorin beta (Synonyms: [b]-tectorin, Tctnb) | |
Results | Reference |
1 | J:245765 Goodyear RJ, Lu X, Deans MR, Richardson GP, A tectorin-based matrix and planar cell polarity genes are required for normal collagen-fibril orientation in the developing tectorial membrane. Development. 2017 Nov 01;144(21):3978-3989 |
Tek TEK receptor tyrosine kinase (Synonyms: Cd202b, Hyk, tie-2, Tie2) | |
Results | Reference |
1 | J:71816 Ayadi A, Zheng H, Sobieszczuk P, Buchwalter G, Moerman P, Alitalo K, Wasylyk B, Net-targeted mutant mice develop a vascular phenotype and up-regulate egr-1. EMBO J. 2001 Sep 17;20(18):5139-52 |
1 | J:311143 Courtney JA, Wilson RL, Cnota J, Jones HN, Conditional Mutation of Hand1 in the Mouse Placenta Disrupts Placental Vascular Development Resulting in Fetal Loss in Both Early and Late Pregnancy. Int J Mol Sci. 2021 Sep 2;22(17) |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1 | J:302486 Jiang X, Tian W, Granucci EJ, Tu AB, Kim D, Dahms P, Pasupneti S, Peng G, Kim Y, Lim AH, Espinoza FH, Cribb M, Dixon JB, Rockson SG, Semenza GL, Nicolls MR, Decreased lymphatic HIF-2alpha accentuates lymphatic remodeling in lymphedema. J Clin Invest. 2020 Oct 1;130(10):5562-5575 |
1 | J:262023 Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K, Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling. Circ Res. 2017 Apr 14;120(8):1276-1288 |
2 | J:281274 Qu X, Violette K, Sewell-Loftin MK, Soslow J, Saint-Jean L, Hinton RB, Merryman WD, Baldwin HS, Loss of flow responsive Tie1 results in ImpairedAortic valve remodeling. Dev Biol. 2019 Nov 1;455(1):73-84 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
2* | J:57001 Yuan HT, Suri C, Yancopoulos GD, Woolf AS, Expression of angiopoietin-1, angiopoietin-2, and the Tie-2 receptor tyrosine kinase during mouse kidney maturation. J Am Soc Nephrol. 1999 Aug;10(8):1722-36 |
Tenm1 teneurin transmembrane protein 1 (Synonyms: Odz1, TCAP-1, teneurin-1, Ten-m1) | |
Results | Reference |
1 | J:348278 Liakath-Ali K, Refaee R, Sudhof TC, Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development. PLoS Biol. 2024 May;22(5):e3002599 |
Tenm2 teneurin transmembrane protein 2 (Synonyms: 2610040L17Rik, 9330187F13Rik, D3Bwg1534e, mKIAA1127, Odz2, Ten-m2) | |
Results | Reference |
1 | J:348278 Liakath-Ali K, Refaee R, Sudhof TC, Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development. PLoS Biol. 2024 May;22(5):e3002599 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Tenm3 teneurin transmembrane protein 3 (Synonyms: 2610100B16Rik, mKIAA1455, Odz3, Ten-m3) | |
Results | Reference |
1 | J:348278 Liakath-Ali K, Refaee R, Sudhof TC, Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development. PLoS Biol. 2024 May;22(5):e3002599 |
1* | J:114661 Lyu YL, Lin CP, Azarova AM, Cai L, Wang JC, Liu LF, Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Mol Cell Biol. 2006 Nov;26(21):7929-41 |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Tenm4 teneurin transmembrane protein 4 (Synonyms: Doc4, ELM2, l(7)-3Rn, l7Rn3, mKIAA1302, Odz4, Ten-m4) | |
Results | Reference |
1 | J:152858 Garcia-Ortiz JE, Pelosi E, Omari S, Nedorezov T, Piao Y, Karmazin J, Uda M, Cao A, Cole SW, Forabosco A, Schlessinger D, Ottolenghi C, Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Dev Biol. 2009;9:36 |
1 | J:348278 Liakath-Ali K, Refaee R, Sudhof TC, Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development. PLoS Biol. 2024 May;22(5):e3002599 |
Tent5a terminal nucleotidyltransferase 5A (Synonyms: BAP014, D930050G01Rik, Fam46a) | |
Results | Reference |
1* | J:156193 Etokebe GE, Kuchler AM, Haraldsen G, Landin M, Osmundsen H, Dembic Z, Family-with-sequence-similarity-46, member A (Fam46a) gene is expressed in developing tooth buds. Arch Oral Biol. 2009 Nov;54(11):1002-7 |
Tent5c terminal nucleotidyltransferase 5C (Synonyms: 4930431B09Rik, Fam46c) | |
Results | Reference |
1* | J:307860 Choquet H, Melles RB, Anand D, Yin J, Cuellar-Partida G, Wang W, Hoffmann TJ, Nair KS, Hysi PG, Lachke SA, Jorgenson E, A large multiethnic GWAS meta-analysis of cataract identifies new risk loci and sex-specific effects. Nat Commun. 2021 Jun 14;12(1):3595 |
Terb1 telomere repeat binding bouquet formation protein 1 (Synonyms: 4930532D21Rik, Ccdc79) | |
Results | Reference |
1 | J:242462 Daniel K, Trankner D, Wojtasz L, Shibuya H, Watanabe Y, Alsheimer M, Toth A, Mouse CCDC79 (TERB1) is a meiosis-specific telomere associated protein. BMC Cell Biol. 2014 May 22;15:17 |
Terf1 telomeric repeat binding factor 1 (Synonyms: Pin2, Trbf1, Trf1) | |
Results | Reference |
1* | J:347585 Leon NY, Le TNU, Garvie A, Wong LH, Bagheri-Fam S, Harley VR, Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. iScience. 2024 May 17;27(5):109629 |
Terf2 telomeric repeat binding factor 2 (Synonyms: TRF2) | |
Results | Reference |
1 | J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39 |
Tesc tescalcin (Synonyms: 1010001A17Rik, 2410011K10Rik, TE-1) | |
Results | Reference |
1 | J:341713 Aure MH, Symonds JM, Villapudua CU, Dodge JT, Werner S, Knosp WM, Hoffman MP, FGFR2 is essential for salivary gland duct homeostasis and MAPK-dependent seromucous acinar cell differentiation. Nat Commun. 2023 Oct 14;14(1):6485 |
1* | J:148940 Bao Y, Hudson QJ, Perera EM, Akan L, Tobet SA, Smith CA, Sinclair AH, Berkovitz GD, Expression and evolutionary conservation of the tescalcin gene during development. Gene Expr Patterns. 2009 Jun;9(5):273-81 |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
1 | J:67267 Perera EM, Martin H, Seeherunvong T, Kos L, Hughes IA, Hawkins JR, Berkovitz GD, Tescalcin, a novel gene encoding a putative EF-hand Ca(2+)-binding protein, Col9a3, and renin are expressed in the mouse testis during the early stages of gonadal differentiation. Endocrinology. 2001 Jan;142(1):455-63 |
Tesmin testis expressed metallothionein like (Synonyms: Mtl5, tesmin) | |
Results | Reference |
1* | J:87821 Olesen C, Moller M, Byskov AG, Tesmin transcription is regulated differently during male and female meiosis. Mol Reprod Dev. 2004 Jan;67(1):116-26 |
Tet1 tet methylcytosine dioxygenase 1 (Synonyms: 2510010B09Rik, BB001228, Cxxc6, D10Ertd17e, mKIAA1676) | |
Results | Reference |
2 | J:326201 Hayashi T, Eto K, Kadoya Y, Downregulation of ten-eleven translocation-2 triggers epithelial differentiation during organogenesis. Differentiation. 2022 May-Jun;125:45-53 |
1 | J:234375 Kim H, Jang WY, Kang MC, Jeong J, Choi M, Sung Y, Park S, Kwon W, Jang S, Kim MO, Kim SH, Ryoo ZY, TET1 contributes to neurogenesis onset time during fetal brain development in mice. Biochem Biophys Res Commun. 2016 Mar 18;471(4):437-43 |
1* | J:258221 Rakoczy J, Padmanabhan N, Krzak AM, Kieckbusch J, Cindrova-Davies T, Watson ED, Dynamic expression of TET1, TET2, and TET3 dioxygenases in mouse and human placentas throughout gestation. Placenta. 2017 Nov;59:46-56 |
1 | J:194101 Yamaguchi S, Hong K, Liu R, Shen L, Inoue A, Diep D, Zhang K, Zhang Y, Tet1 controls meiosis by regulating meiotic gene expression. Nature. 2012 Dec 20;492(7429):443-7 |
Tet2 tet methylcytosine dioxygenase 2 (Synonyms: Ayu17-449, E130014J05Rik, mKIAA1546) | |
Results | Reference |
2 | J:326201 Hayashi T, Eto K, Kadoya Y, Downregulation of ten-eleven translocation-2 triggers epithelial differentiation during organogenesis. Differentiation. 2022 May-Jun;125:45-53 |
1* | J:258221 Rakoczy J, Padmanabhan N, Krzak AM, Kieckbusch J, Cindrova-Davies T, Watson ED, Dynamic expression of TET1, TET2, and TET3 dioxygenases in mouse and human placentas throughout gestation. Placenta. 2017 Nov;59:46-56 |
1 | J:194101 Yamaguchi S, Hong K, Liu R, Shen L, Inoue A, Diep D, Zhang K, Zhang Y, Tet1 controls meiosis by regulating meiotic gene expression. Nature. 2012 Dec 20;492(7429):443-7 |
Tet3 tet methylcytosine dioxygenase 3 (Synonyms: B430006D22Rik, D230004J03Rik) | |
Results | Reference |
1 | J:326201 Hayashi T, Eto K, Kadoya Y, Downregulation of ten-eleven translocation-2 triggers epithelial differentiation during organogenesis. Differentiation. 2022 May-Jun;125:45-53 |
1* | J:258221 Rakoczy J, Padmanabhan N, Krzak AM, Kieckbusch J, Cindrova-Davies T, Watson ED, Dynamic expression of TET1, TET2, and TET3 dioxygenases in mouse and human placentas throughout gestation. Placenta. 2017 Nov;59:46-56 |
1 | J:194101 Yamaguchi S, Hong K, Liu R, Shen L, Inoue A, Diep D, Zhang K, Zhang Y, Tet1 controls meiosis by regulating meiotic gene expression. Nature. 2012 Dec 20;492(7429):443-7 |
Tex11 testis expressed gene 11 (Synonyms: 4930565P14Rik) | |
Results | Reference |
2 | J:347973 Li Y, Wu Y, Khan I, Zhou J, Lu Y, Ye J, Liu J, Xie X, Hu C, Jiang H, Fan S, Zhang H, Zhang Y, Jiang X, Xu B, Ma H, Shi Q, M1AP interacts with the mammalian ZZS complex and promotes male meiotic recombination. EMBO Rep. 2023 Feb 6;24(2):e55778 |
Tex12 testis expressed 12 (Synonyms: 5730518K06Rik) | |
Results | Reference |
1 | J:182264 Kouznetsova A, Benavente R, Pastink A, Hoog C, Meiosis in mice without a synaptonemal complex. PLoS One. 2011;6(12):e28255 |
Tex15 testis expressed gene 15 meiosis and synapsis associated (Synonyms: 2210014E14Rik) | |
Results | Reference |
1 | J:291848 Schopp T, Zoch A, Berrens RV, Auchynnikava T, Kabayama Y, Vasiliauskaite L, Rappsilber J, Allshire RC, O'Carroll D, TEX15 is an essential executor of MIWI2-directed transposon DNA methylation and silencing. Nat Commun. 2020 Jul 27;11(1):3739 |
1* | J:288732 Yang F, Lan Y, Pandey RR, Homolka D, Berger SL, Pillai RS, Bartolomei MS, Wang PJ, TEX15 associates with MILI and silences transposable elements in male germ cells. Genes Dev. 2020 Jun 1;34(11-12):745-750 |
Tex19.1 testis expressed gene 19.1 (Synonyms: 2410081M02Rik, Tex19, Tex19.1) | |
Results | Reference |
2* | J:186276 Celebi C, van Montfoort A, Skory V, Kieffer E, Kuntz S, Mark M, Viville S, Tex 19 Paralogs Exhibit a Gonad and Placenta-Specific Expression in the Mouse. J Reprod Dev. 2012 Jul 3;58(3):360-5 |
1* | J:133713 Kuntz S, Kieffer E, Bianchetti L, Lamoureux N, Fuhrmann G, Viville S, Tex19, a mammalian-specific protein with a restricted expression in pluripotent stem cells and germ line. Stem Cells. 2008 Mar;26(3):734-44 |
Tex19.2 testis expressed gene 19.2 (Synonyms: 4921530G04Rik, Tex19.2) | |
Results | Reference |
2* | J:186276 Celebi C, van Montfoort A, Skory V, Kieffer E, Kuntz S, Mark M, Viville S, Tex 19 Paralogs Exhibit a Gonad and Placenta-Specific Expression in the Mouse. J Reprod Dev. 2012 Jul 3;58(3):360-5 |
1* | J:133713 Kuntz S, Kieffer E, Bianchetti L, Lamoureux N, Fuhrmann G, Viville S, Tex19, a mammalian-specific protein with a restricted expression in pluripotent stem cells and germ line. Stem Cells. 2008 Mar;26(3):734-44 |
Tex101 testis expressed gene 101 (Synonyms: 1700008H15Rik, TES101RP) | |
Results | Reference |
1* | J:98774 Takayama T, Mishima T, Mori M, Jin H, Tsukamoto H, Takahashi K, Takizawa T, Kinoshita K, Suzuki M, Sato I, Matsubara S, Araki Y, Takizawa T, Sexually Dimorphic Expression of the Novel Germ Cell Antigen TEX101 During Mouse Gonad Development. Biol Reprod. 2005 Jun;72(6):1315-23 |
Tfam transcription factor A, mitochondrial (Synonyms: Hmgts, mtTFA, tsHMG) | |
Results | Reference |
1 | J:356661 Esteban-Martinez L, Sierra-Filardi E, McGreal RS, Salazar-Roa M, Marino G, Seco E, Durand S, Enot D, Grana O, Malumbres M, Cvekl A, Cuervo AM, Kroemer G, Boya P, Programmed mitophagy is essential for the glycolytic switch during cell differentiation. EMBO J. 2017 Jun 14;36(12):1688-1706 |
1* | J:334015 Yoshioka H, Komura S, Kuramitsu N, Goto A, Hasegawa T, Amizuka N, Ishimoto T, Ozasa R, Nakano T, Imai Y, Akiyama H, Deletion of Tfam in Prx1-Cre expressing limb mesenchyme results in spontaneous bone fractures. J Bone Miner Metab. 2022 Sep;40(5):839-852 |
Tfap2a transcription factor AP-2, alpha (Synonyms: Ap2, Ap-2 (a), AP-2 alpha, AP2alpha, Ap2tf, Tcfap2a) | |
Results | Reference |
1* | J:181601 Bassett EA, Korol A, Deschamps PA, Buettner R, Wallace VA, Williams T, West-Mays JA, Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29 |
1* | J:20591 Byrne C, Tainsky M, Fuchs E, Programming gene expression in developing epidermis. Development. 1994 Sep;120(9):2369-83 |
1 | J:304642 Dupacova N, Antosova B, Paces J, Kozmik Z, Meis homeobox genes control progenitor competence in the retina. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2013136118 |
1 | J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489 |
1 | J:249145 Goetz JJ, Laboissonniere LA, Wester AK, Lynch MR, Trimarchi JM, Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression. PLoS One. 2016;11(3):e0150878 |
1 | J:254641 Groman-Lupa S, Adewumi J, Park KU, Brzezinski Iv JA, The Transcription Factor Prdm16 Marks a Single Retinal Ganglion Cell Subtype in the Mouse Retina. Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5421-5433 |
1 | J:237540 Gueta K, David A, Cohen T, Menuchin-Lasowski Y, Nobel H, Narkis G, Li L, Love P, de Melo J, Blackshaw S, Westphal H, Ashery-Padan R, The stage-dependent roles of Ldb1 and functional redundancy with Ldb2 in mammalian retinogenesis. Development. 2016 Nov 15;143(22):4182-4192 |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
1 | J:302827 Jin K, Jiang H, Xiao D, Zou M, Zhu J, Xiang M, Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis. Mol Brain. 2015 May 13;8:28 |
2 | J:173638 Schmidt M, Huber L, Majdazari A, Schutz G, Williams T, Rohrer H, The transcription factors AP-2beta and AP-2alpha are required for survival of sympathetic progenitors and differentiated sympathetic neurons. Dev Biol. 2011 Jul 1;355(1):89-100 |
1 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
1* | J:314172 Sundaram VK, El Jalkh T, Barakat R, Fernandez CJI, Massaad C, Grenier J, Retracing Schwann Cell Developmental Transitions in Embryonic Dissociated DRG/Schwann Cell Cocultures in Mice. Front Cell Neurosci. 2021;15:590537 |
1 | J:154456 Thompson H, Andrews W, Parnavelas JG, Erskine L, Robo2 is required for Slit-mediated intraretinal axon guidance. Dev Biol. 2009 Nov 15;335(2):418-26 |
Tfap2b transcription factor AP-2 beta (Synonyms: AP-2(beta), E130018K07Rik, Tcfap2b) | |
Results | Reference |
1* | J:181601 Bassett EA, Korol A, Deschamps PA, Buettner R, Wallace VA, Williams T, West-Mays JA, Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29 |
1 | J:221018 Farhy C, Elgart M, Shapira Z, Oron-Karni V, Yaron O, Menuchin Y, Rechavi G, Ashery-Padan R, Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells. PLoS One. 2013;8(9):e76489 |
1 | J:249145 Goetz JJ, Laboissonniere LA, Wester AK, Lynch MR, Trimarchi JM, Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression. PLoS One. 2016;11(3):e0150878 |
1 | J:223559 Goetz JJ, Martin GM, Chowdhury R, Trimarchi JM, Onecut1 and Onecut2 play critical roles in the development of the mouse retina. PLoS One. 2014;9(10):e110194 |
2 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:302827 Jin K, Jiang H, Xiao D, Zou M, Zhu J, Xiang M, Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis. Mol Brain. 2015 May 13;8:28 |
1* | J:272508 Ma J, Lwigale P, Transformation of the Transcriptomic Profile of Mouse Periocular Mesenchyme During Formation of the Embryonic Cornea. Invest Ophthalmol Vis Sci. 2019 Feb 1;60(2):661-676 |
1 | J:235721 Menuchin-Lasowski Y, Oren-Giladi P, Xie Q, Ezra-Elia R, Ofri R, Peled-Hajaj S, Farhy C, Higashi Y, Van de Putte T, Kondoh H, Huylebroeck D, Cvekl A, Ashery-Padan R, Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals. Development. 2016 Aug 1;143(15):2829-41 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:173638 Schmidt M, Huber L, Majdazari A, Schutz G, Williams T, Rohrer H, The transcription factors AP-2beta and AP-2alpha are required for survival of sympathetic progenitors and differentiated sympathetic neurons. Dev Biol. 2011 Jul 1;355(1):89-100 |
1 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Tfap2c transcription factor AP-2, gamma (Synonyms: Ap-2.2, AP2gamma, Stra2, Tcfap2c) | |
Results | Reference |
1* | J:181601 Bassett EA, Korol A, Deschamps PA, Buettner R, Wallace VA, Williams T, West-Mays JA, Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina. Dev Dyn. 2012 Apr;241(4):814-29 |
1* | J:136080 Guttormsen J, Koster MI, Stevens JR, Roop DR, Williams T, Winger QA, Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice. Dev Biol. 2008 May 1;317(1):187-95 |
Tfap2d transcription factor AP-2, delta (Synonyms: Tcfap2d) | |
Results | Reference |
1* | J:177585 Hesse K, Vaupel K, Kurt S, Buettner R, Kirfel J, Moser M, AP-2delta is a crucial transcriptional regulator of the posterior midbrain. PLoS One. 2011;6(8):e23483 |
1 | J:316103 Li X, Gaillard F, Monckton EA, Glubrecht DD, Persad AR, Moser M, Sauve Y, Godbout R, Loss of AP-2delta reduces retinal ganglion cell numbers and axonal projections to the superior colliculus. Mol Brain. 2016 Jun 4;9(1):62 |
1* | J:83321 Zhao F, Lufkin T, Gelb BD, Expression of Tfap2d, the gene encoding the transcription factor Ap-2delta, during mouse embryogenesis. Gene Expr Patterns. 2003 May;3(2):213-7 |
Tfap2e transcription factor AP-2, epsilon (Synonyms: AP-2e, Tcfap2e) | |
Results | Reference |
1* | J:86250 Feng W, Williams T, Cloning and characterization of the mouse AP-2epsilon gene: a novel family member expressed in the developing olfactory bulb. Mol Cell Neurosci. 2003 Oct;24(2):460-75 |
2 | J:263083 Jain S, Glubrecht DD, Germain DR, Moser M, Godbout R, AP-2epsilon Expression in Developing Retina: Contributing to the Molecular Diversity of Amacrine Cells. Sci Rep. 2018 Feb 21;8(1):3386 |
1* | J:91733 Wang HV, Vaupel K, Buettner R, Bosserhoff AK, Moser M, Identification and embryonic expression of a new AP-2 transcription factor, AP-2 epsilon. Dev Dyn. 2004 Sep;231(1):128-35 |
Tfcp2l1 transcription factor CP2-like 1 (Synonyms: 1810030F05Rik, 4932442M07Rik, Cp2l1, Crtr-1, D930018N21Rik, LBP-9, Tcfcp2l1) | |
Results | Reference |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
2 | J:67293 Rodda S, Sharma S, Scherer M, Chapman G, Rathjen P, CRTR-1, a developmentally regulated transcriptional repressor related to the CP2 family of transcription factors. J Biol Chem. 2001 Feb 2;276(5):3324-32 |
Tfdp1 transcription factor Dp 1 (Synonyms: Dp1, Drtf1) | |
Results | Reference |
1* | J:40858 Dagnino L, Fry CJ, Bartley SM, Farnham P, Gallie BL, Phillips RA, Expression patterns of the E2F family of transcription factors during murine epithelial development. Cell Growth Differ. 1997 May;8(5):553-63 |
1* | J:37674 Gopalkrishnan RV, Dolle P, Mattei MG, La Thangue NB, Kedinger C, Genomic structure and developmental expression of the mouse cell cycle regulatory transcription factor DP1. Oncogene. 1996 Dec 19;13(12):2671-80 |
2* | J:31363 Tevosian SG, Paulson KE, Bronson R, Yee AS, Expression of the E2F-1/DP-1 transcription factor in murine development. Cell Growth Differ. 1996 Jan;7(1):43-52 |
Tfeb transcription factor EB (Synonyms: bHLHe35, Tcfeb, TFEB) | |
Results | Reference |
1* | J:161201 Gao N, Kaestner KH, Cdx2 regulates endo-lysosomal function and epithelial cell polarity. Genes Dev. 2010 Jun 15;24(12):1295-305 |
Tfec transcription factor EC (Synonyms: bHLHe34, Tcfec, TFEC) | |
Results | Reference |
1* | J:154372 Li X, Udager AM, Hu C, Qiao XT, Richards N, Gumucio DL, Dynamic patterning at the pylorus: Formation of an epithelial intestine-stomach boundary in late fetal life. Dev Dyn. 2009 Oct 29;238(12):3205-3217 |
Tff1 trefoil factor 1 (Synonyms: Bcei, PS2) | |
Results | Reference |
1 | J:318863 Belovari T, Bijelic N, Tolusic Levak M, Baus Loncar M, Trefoil factor family peptides TFF1 and TFF3 in the nervous tissues of developing mouse embryo. Bosn J Basic Med Sci. 2015 Feb 1;15(1):33-7 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
1 | J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461 |
Tff2 trefoil factor 2 (spasmolytic protein 1) (Synonyms: mSP, SP) | |
Results | Reference |
2 | J:275470 Hirata K, Kodama S, Nakano Y, Minaki-Nakagawa Y, Aoyama Y, Sakikubo M, Goto T, Yoshida M, Masui T, Yamamoto T, Uemoto S, Kawaguchi Y, Exocrine tissue-driven TFF2 prevents apoptotic cell death of endocrine lineage during pancreas organogenesis. Sci Rep. 2019 Feb 7;9(1):1636 |
1 | J:134393 Nyeng P, Norgaard GA, Kobberup S, Jensen J, FGF10 signaling controls stomach morphogenesis. Dev Biol. 2007 Mar 1;303(1):295-310 |
2 | J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461 |
Tff3 trefoil factor 3, intestinal (Synonyms: ITF, mITF) | |
Results | Reference |
1 | J:318863 Belovari T, Bijelic N, Tolusic Levak M, Baus Loncar M, Trefoil factor family peptides TFF1 and TFF3 in the nervous tissues of developing mouse embryo. Bosn J Basic Med Sci. 2015 Feb 1;15(1):33-7 |
1* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
1 | J:353482 Ortiz JA, Ghazalli N, Lopez K, Rawson J, McCown EM, Oh E, Irimia JM, Jou K, Mares J, Chen MH, Wu X, Zook HN, Quijano JC, Erdem N, Lizarraga A, Kandeel F, Fueger PT, Thurmond DC, Ku HT, Trefoil Factor 2 Expressed by the Murine Pancreatic Acinar Cells Is Required for the Development of Islets and for beta-Cell Function During Aging. Diabetes. 2024 Sep 1;73(9):1447-1461 |
1* | J:137338 Paulsen FP, Woon CW, Varoga D, Jansen A, Garreis F, Jager K, Amm M, Podolsky DK, Steven P, Barker NP, Sel S, Intestinal trefoil factor/TFF3 promotes re-epithelialization of corneal wounds. J Biol Chem. 2008 May 9;283(19):13418-27 |
Tfg Trk-fused gene | |
Results | Reference |
2 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
Tfpi tissue factor pathway inhibitor (Synonyms: A630013F22Rik) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Tfpi2 tissue factor pathway inhibitor 2 (Synonyms: PP5/TFPI-2) | |
Results | Reference |
1* | J:267655 Marjonen H, Toivonen M, Lahti L, Kaminen-Ahola N, Early prenatal alcohol exposure alters imprinted gene expression in placenta and embryo in a mouse model. PLoS One. 2018;13(5):e0197461 |
Tfrc transferrin receptor (Synonyms: 2610028K12Rik, CD71, E430033M20Rik, Mtvr-1, Mtvr1, p90, TfR1, Trfr) | |
Results | Reference |
1 | J:250166 Liu K, Lei R, Li Q, Wang XX, Wu Q, An P, Zhang J, Zhu M, Xu Z, Hong Y, Wang F, Shen Y, Li H, Li H, Transferrin Receptor Controls AMPA Receptor Trafficking Efficiency and Synaptic Plasticity. Sci Rep. 2016 Feb 16;6:21019 |
Tg thyroglobulin (Synonyms: Tgn) | |
Results | Reference |
1* | J:296875 Carre A, Gawade S, Dertschnig S, Hafen K, Polak M, Szinnai G, Ex vivo model for elucidating the functional and structural differentiation of the embryonic mouse thyroid. Mol Cell Endocrinol. 2020 Jun 15;510:110834 |
1* | J:171072 Carre A, Rachdi L, Tron E, Richard B, Castanet M, Schlumberger M, Bidart JM, Szinnai G, Polak M, Hes1 is required for appropriate morphogenesis and differentiation during mouse thyroid gland development. PLoS One. 2011;6(2):e16752 |
1 | J:146225 Kameda Y, Ito M, Nishimaki T, Gotoh N, FRS2alpha is required for the separation, migration, and survival of pharyngeal-endoderm derived organs including thyroid, ultimobranchial body, parathyroid, and thymus. Dev Dyn. 2009 Mar;238(3):503-13 |
1* | J:84449 Meunier D, Aubin J, Jeannotte L, Perturbed thyroid morphology and transient hypothyroidism symptoms in Hoxa5 mutant mice. Dev Dyn. 2003 Jul;227(3):367-78 |
1 | J:144862 Newbern J, Zhong J, Wickramasinghe RS, Li X, Wu Y, Samuels I, Cherosky N, Karlo JC, O'Loughlin B, Wikenheiser J, Gargesha M, Doughman YQ, Charron J, Ginty DD, Watanabe M, Saitta SC, Snider WD, Landreth GE, Mouse and human phenotypes indicate a critical conserved role for ERK2 signaling in neural crest development. Proc Natl Acad Sci U S A. 2008 Nov 4;105(44):17115-20 |
1 | J:80538 Postiglione MP, Parlato R, Rodriguez-Mallon A, Rosica A, Mithbaokar P, Maresca M, Marians RC, Davies TF, Zannini MS, De Felice M, Di Lauro R, Role of the thyroid-stimulating hormone receptor signaling in development and differentiation of the thyroid gland. Proc Natl Acad Sci U S A. 2002 Nov 26;99(24):15462-7 |
1 | J:169693 Silberschmidt D, Rodriguez-Mallon A, Mithboakar P, Cali G, Amendola E, Sanges R, Zannini M, Scarfo M, De Luca P, Nitsch L, Di Lauro R, De Felice M, In vivo role of different domains and of phosphorylation in the transcription factor Nkx2-1. BMC Dev Biol. 2011;11:9 |
Tgfa transforming growth factor alpha | |
Results | Reference |
1* | J:36353 Berkowitz EA, Seroogy KB, Schroeder JA, Russell WE, Evans EP, Riedel RF, Phillips HK, Harrison CA, Lee DC, Luetteke NC, Characterization of the mouse transforming growth factor alpha gene: its expression during eyelid development and in waved 1 tissues. Cell Growth Differ. 1996 Sep;7(9):1271-82 |
1* | J:299515 Bezamat M, Souza JF, Silva FMF, Correa EG, Fatturi AL, Brancher JA, Carvalho FM, Cavallari T, Bertolazo L, Machado-Souza C, Koruyucu M, Bayram M, Racic A, Harrison BM, Sweat YY, Letra A, Studen-Pavlovich D, Seymen F, Amendt B, Werneck RI, Costa MC, Modesto A, Vieira AR, Gene-environment interaction in molar-incisor hypomineralization. PLoS One. 2021;16(1):e0241898 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
2 | J:38205 Kashimata M, Gresik EW, Epidermal growth factor system is a physiological regulator of development of the mouse fetal submandibular gland and regulates expression of the alpha6-integrin subunit. Dev Dyn. 1997 Feb;208(2):149-61 |
1 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1* | J:130339 Minami S, Iwamoto R, Mekada E, HB-EGF decelerates cell proliferation synergistically with TGFalpha in perinatal distal lung development. Dev Dyn. 2008 Jan;237(1):247-58 |
1 | J:93433 Weston CR, Wong A, Hall JP, Goad ME, Flavell RA, Davis RJ, The c-Jun NH2-terminal kinase is essential for epidermal growth factor expression during epidermal morphogenesis. Proc Natl Acad Sci U S A. 2004 Oct 28;101(39):14114-9 |
1* | J:137275 Yu Z, Bhandari A, Mannik J, Pham T, Xu X, Andersen B, Grainyhead-like factor Get1/Grhl3 regulates formation of the epidermal leading edge during eyelid closure. Dev Biol. 2008 Jul 1;319(1):56-67 |
Tgfb1 transforming growth factor, beta 1 (Synonyms: Tgfb, Tgfb-1, TGF-beta 1, TGF-beta1, TGFbeta1) | |
Results | Reference |
1* | J:33496 Akhurst RJ, Lehnert SA, Faissner A, Duffie E, TGF beta in murine morphogenetic processes: the early embryo and cardiogenesis. Development. 1990 Apr;108(4):645-56 |
1 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
1 | J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400 |
1 | J:213791 Dutta DJ, Zameer A, Mariani JN, Zhang J, Asp L, Huynh J, Mahase S, Laitman BM, Argaw AT, Mitiku N, Urbanski M, Melendez-Vasquez CV, Casaccia P, Hayot F, Bottinger EP, Brown CW, John GR, Combinatorial actions of Tgfbeta and Activin ligands promote oligodendrocyte development and CNS myelination. Development. 2014 Jun;141(12):2414-28 |
1* | J:75698 Grunder A, Ebel TT, Mallo M, Schwarzkopf G, Shimizu T, Sippel AE, Schrewe H, Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia. Mech Dev. 2002 Mar;112(1-2):69-77 |
3 | J:196581 Gui T, Sun Y, Gai Z, Shimokado A, Muragaki Y, Zhou G, The loss of Trps1 suppresses ureteric bud branching because of the activation of TGF-beta signaling. Dev Biol. 2013 May 15;377(2):415-27 |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
2 | J:200638 Islam SS, Mokhtari RB, Kumar S, Maalouf J, Arab S, Yeger H, Farhat WA, Spatio-temporal distribution of Smads and role of Smads/TGF-beta/BMP-4 in the regulation of mouse bladder organogenesis. PLoS One. 2013;8(4):e61340 |
2 | J:41235 Kaestner KH, Silberg DG, Traber PG, Schutz G, The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation. Genes Dev. 1997 Jun 15;11(12):1583-95 |
1 | J:188148 Landin MA, Shabestari M, Babaie E, Reseland JE, Osmundsen H, Gene Expression Profiling during Murine Tooth Development. Front Genet. 2012;3:139 |
1* | J:250161 Lee AJ, Polgar N, Napoli JA, Lui VH, Tamashiro KK, Fujimoto BA, Thompson KS, Fogelgren B, Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy. Sci Rep. 2016 Aug 11;6:31137 |
1* | J:257228 Li S, Pan Y, Differential expression of transforming growth factor-beta1, connective tissue growth factor, phosphorylated-SMAD2/3 and phosphorylated-ERK1/2 during mouse tooth development. J Mol Histol. 2017 Dec;48(5-6):347-355 |
1* | J:28117 Mahmood R, Flanders KC, Morriss-Kay GM, The effects of retinoid status on TGF beta expression during mouse embryogenesis. Anat Embryol (Berl). 1995 Jul;192(1):21-33 |
1* | J:11119 Millan FA, Denhez F, Kondaiah P, Akhurst RJ, Embryonic gene expression patterns of TGF beta 1, beta 2 and beta 3 suggest different developmental functions in vivo. Development. 1991 Jan;111(1):131-43 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
2* | J:49900 Montuenga LM, Mariano JM, Prentice MA, Cuttitta F, Jakowlew SB, Coordinate expression of transforming growth factor-beta1 and adrenomedullin in rodent embryogenesis. Endocrinology. 1998 Sep;139(9):3946-57 |
1 | J:160474 Moreno SG, Attali M, Allemand I, Messiaen S, Fouchet P, Coffigny H, Romeo PH, Habert R, TGFbeta signaling in male germ cells regulates gonocyte quiescence and fertility in mice. Dev Biol. 2010 Jun 1;342(1):74-84 |
1 | J:361601 Park CJ, Oh JE, Lin P, Zhou S, Bunnell M, Bikorimana E, Spinella MJ, Lim HJ, Ko CJ, A Dynamic Shift in Estrogen Receptor Expression During Granulosa Cell Differentiation in the Ovary. Endocrinology. 2025 Jan 6;166(2) |
1* | J:11609 Pelton RW, Dickinson ME, Moses HL, Hogan BL, In situ hybridization analysis of TGF beta 3 RNA expression during mouse development: comparative studies with TGF beta 1 and beta 2. Development. 1990 Oct;110(2):609-20 |
1* | J:43626 Pelton RW, Saxena B, Jones M, Moses HL, Gold LI, Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. J Cell Biol. 1991 Nov;115(4):1091-105 |
1 | J:321171 Safwan-Zaiter H, Wagner N, Michiels JF, Wagner KD, Dynamic Spatiotemporal Expression Pattern of the Senescence-Associated Factor p16Ink4a in Development and Aging. Cells. 2022 Feb 4;11(3) |
1* | J:31180 Schmid P, Cox D, Bilbe G, Maier R, McMaster GK, Differential expression of TGF beta 1, beta 2 and beta 3 genes during mouse embryogenesis. Development. 1991 Jan;111(1):117-30 |
1 | J:171003 Sugito H, Shibukawa Y, Kinumatsu T, Yasuda T, Nagayama M, Yamada S, Minugh-Purvis N, Pacifici M, Koyama E, Ihh signaling regulates mandibular symphysis development and growth. J Dent Res. 2011 May;90(5):625-31 |
1 | J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521 |
1 | J:11717 Vaahtokari A, Vainio S, Thesleff I, Associations between transforming growth factor beta 1 RNA expression and epithelial-mesenchymal interactions during tooth morphogenesis. Development. 1991 Nov;113(3):985-94 |
1 | J:346785 Wang S, Zhang H, Wiltshire T, Sealock R, Faber JE, Genetic dissection of the Canq1 locus governing variation in extent of the collateral circulation. PLoS One. 2012;7(3):e31910 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Tgfb1i1 transforming growth factor beta 1 induced transcript 1 (Synonyms: ARA55, hic-5, TSC-5) | |
Results | Reference |
1* | J:70363 Brunskill EW, Witte DP, Yutzey KE, Potter SS, Novel cell lines promote the discovery of genes involved in early heart development. Dev Biol. 2001 Jul 15;235(2):507-20 |
Tgfb2 transforming growth factor, beta 2 (Synonyms: Tgfb-2, Tgf-beta2) | |
Results | Reference |
1 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
1* | J:17727 Burns TM, Clough JA, Klein RM, Wood GW, Berman NE, Developmental regulation of cytokine expression in the mouse brain. Growth Factors. 1993;9(4):253-8 |
1 | J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1* | J:75698 Grunder A, Ebel TT, Mallo M, Schwarzkopf G, Shimizu T, Sippel AE, Schrewe H, Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia. Mech Dev. 2002 Mar;112(1-2):69-77 |
1 | J:236173 Guo W, Benlhabib H, Mendelson CR, The MicroRNA 29 Family Promotes Type II Cell Differentiation in Developing Lung. Mol Cell Biol. 2016 Aug 15;36(16):2141 |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
2 | J:213572 Ishtiaq Ahmed AS, Bose GC, Huang L, Azhar M, Generation of mice carrying a knockout-first and conditional-ready allele of transforming growth factor beta2 gene. Genesis. 2014 Sep;52(9):817-26 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
2 | J:41235 Kaestner KH, Silberg DG, Traber PG, Schutz G, The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation. Genes Dev. 1997 Jun 15;11(12):1583-95 |
1* | J:145162 Li JY, Hu B, Wang XJ, Wang SL, Temporal and spatial expression of TGF-beta2 in tooth crown development in mouse first lower molar. Eur J Histochem. 2008 Oct-Dec;52(4):243-50 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1* | J:11119 Millan FA, Denhez F, Kondaiah P, Akhurst RJ, Embryonic gene expression patterns of TGF beta 1, beta 2 and beta 3 suggest different developmental functions in vivo. Development. 1991 Jan;111(1):131-43 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:160474 Moreno SG, Attali M, Allemand I, Messiaen S, Fouchet P, Coffigny H, Romeo PH, Habert R, TGFbeta signaling in male germ cells regulates gonocyte quiescence and fertility in mice. Dev Biol. 2010 Jun 1;342(1):74-84 |
1* | J:52221 Paradies NE, Sanford LP, Doetschman T, Friedman RA, Developmental expression of the TGF beta s in the mouse cochlea. Mech Dev. 1998 Dec;79(1-2):165-8 |
1* | J:11609 Pelton RW, Dickinson ME, Moses HL, Hogan BL, In situ hybridization analysis of TGF beta 3 RNA expression during mouse development: comparative studies with TGF beta 1 and beta 2. Development. 1990 Oct;110(2):609-20 |
1* | J:43626 Pelton RW, Saxena B, Jones M, Moses HL, Gold LI, Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. J Cell Biol. 1991 Nov;115(4):1091-105 |
1* | J:31180 Schmid P, Cox D, Bilbe G, Maier R, McMaster GK, Differential expression of TGF beta 1, beta 2 and beta 3 genes during mouse embryogenesis. Development. 1991 Jan;111(1):117-30 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1 | J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521 |
2 | J:256746 Wang X, Shan X, Gregory-Evans CY, A mouse model of aniridia reveals the in vivo downstream targets of Pax6 driving iris and ciliary body development in the eye. Biochim Biophys Acta. 2017 Jan;1863(1):60-67 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
Tgfb3 transforming growth factor, beta 3 (Synonyms: Tgfb-3) | |
Results | Reference |
1 | J:128363 Arai KY, Nishiyama T, Developmental Changes in Extracellular Matrix Messenger RNAs in the Mouse Placenta During the Second Half of Pregnancy: Possible Factors Involved in the Regulation of Placental Extracellular Matrix Expression. Biol Reprod. 2007 Dec;77(6):923-33 |
1* | J:75698 Grunder A, Ebel TT, Mallo M, Schwarzkopf G, Shimizu T, Sippel AE, Schrewe H, Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia. Mech Dev. 2002 Mar;112(1-2):69-77 |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:317512 Jalali A, Zhu X, Liu C, Nawshad A, Induction of palate epithelial mesenchymal transition by transforming growth factor beta3 signaling. Dev Growth Differ. 2012 Aug;54(6):633-48 |
1 | J:137800 Jin JZ, Li Q, Higashi Y, Darling DS, Ding J, Analysis of Zfhx1a mutant mice reveals palatal shelf contact-independent medial edge epithelial differentiation during palate fusion. Cell Tissue Res. 2008 Jul;333(1):29-38 |
2 | J:41235 Kaestner KH, Silberg DG, Traber PG, Schutz G, The mesenchymal winged helix transcription factor Fkh6 is required for the control of gastrointestinal proliferation and differentiation. Genes Dev. 1997 Jun 15;11(12):1583-95 |
1 | J:308704 Kiyokawa H, Yamaoka A, Matsuoka C, Tokuhara T, Abe T, Morimoto M, Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfbeta-Id2 axis, for tissue regeneration. Dev Cell. 2021 Jul 12;56(13):1917-1929.e9 |
1 | J:225061 Kouskoura T, Kozlova A, Alexiou M, Blumer S, Zouvelou V, Katsaros C, Chiquet M, Mitsiadis TA, Graf D, The etiology of cleft palate formation in BMP7-deficient mice. PLoS One. 2013;8(3):e59463 |
1* | J:11119 Millan FA, Denhez F, Kondaiah P, Akhurst RJ, Embryonic gene expression patterns of TGF beta 1, beta 2 and beta 3 suggest different developmental functions in vivo. Development. 1991 Jan;111(1):131-43 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:160474 Moreno SG, Attali M, Allemand I, Messiaen S, Fouchet P, Coffigny H, Romeo PH, Habert R, TGFbeta signaling in male germ cells regulates gonocyte quiescence and fertility in mice. Dev Biol. 2010 Jun 1;342(1):74-84 |
1* | J:11609 Pelton RW, Dickinson ME, Moses HL, Hogan BL, In situ hybridization analysis of TGF beta 3 RNA expression during mouse development: comparative studies with TGF beta 1 and beta 2. Development. 1990 Oct;110(2):609-20 |
1* | J:43626 Pelton RW, Saxena B, Jones M, Moses HL, Gold LI, Immunohistochemical localization of TGF beta 1, TGF beta 2, and TGF beta 3 in the mouse embryo: expression patterns suggest multiple roles during embryonic development. J Cell Biol. 1991 Nov;115(4):1091-105 |
1* | J:31180 Schmid P, Cox D, Bilbe G, Maier R, McMaster GK, Differential expression of TGF beta 1, beta 2 and beta 3 genes during mouse embryogenesis. Development. 1991 Jan;111(1):117-30 |
1 | J:156253 Tateossian H, Hardisty-Hughes RE, Morse S, Romero MR, Hilton H, Dean C, Brown SD, Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant. Pathogenetics. 2009;2(1):5 |
1 | J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521 |
Tgfbi transforming growth factor, beta induced (Synonyms: 68kDa, Beta-ig, bIG-h3) | |
Results | Reference |
1* | J:155785 Brinkmeier ML, Davis SW, Carninci P, MacDonald JW, Kawai J, Ghosh D, Hayashizaki Y, Lyons RH, Camper SA, Discovery of transcriptional regulators and signaling pathways in the developing pituitary gland by bioinformatic and genomic approaches. Genomics. 2009 May;93(5):449-60 |
1* | J:85509 Ferguson JW, Mikesh MF, Wheeler EF, LeBaron RG, Developmental expression patterns of Beta-ig (betaIG-H3) and its function as a cell adhesion protein. Mech Dev. 2003 Aug;120(8):851-64 |
1 | J:84735 Ferguson JW, Thoma BS, Mikesh MF, Kramer RH, Bennett KL, Purchio A, Bellard BJ, LeBaron RG, The extracellular matrix protein betaIG-H3 is expressed at myotendinous junctions and supports muscle cell adhesion. Cell Tissue Res. 2003 Jul;313(1):93-105 |
1 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
1* | J:63731 Schorderet DF, Menasche M, Morand S, Bonnel S, Buchillier V, Marchant D, Auderset K, Bonny C, Abitbol M, Munier FL, Genomic characterization and embryonic expression of the mouse Bigh3 (Tgfbi) gene. Biochem Biophys Res Commun. 2000 Aug 2;274(2):267-74 |
Tgfbr1 transforming growth factor, beta receptor I (Synonyms: Alk-5, ALK5, TbetaR-I, TbetaRI) | |
Results | Reference |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1* | J:75698 Grunder A, Ebel TT, Mallo M, Schwarzkopf G, Shimizu T, Sippel AE, Schrewe H, Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia. Mech Dev. 2002 Mar;112(1-2):69-77 |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1 | J:250062 Li A, Ma S, Smith SM, Lee MK, Fischer A, Borok Z, Bellusci S, Li C, Minoo P, Mesodermal ALK5 controls lung myofibroblast versus lipofibroblast cell fate. BMC Biol. 2016 Mar 16;14:19 |
2* | J:51497 Mariano JM, Montuenga LM, Prentice MA, Cuttitta F, Jakowlew SB, Concurrent and distinct transcription and translation of transforming growth factor-beta type I and type II receptors in rodent embryogenesis. Int J Dev Biol. 1998 Nov;42(8):1125-36 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1* | J:103164 Minina E, Schneider S, Rosowski M, Lauster R, Vortkamp A, Expression of Fgf and Tgfbeta signaling related genes during embryonic endochondral ossification. Gene Expr Patterns. 2005 Dec;6(1):102-109 |
1 | J:160474 Moreno SG, Attali M, Allemand I, Messiaen S, Fouchet P, Coffigny H, Romeo PH, Habert R, TGFbeta signaling in male germ cells regulates gonocyte quiescence and fertility in mice. Dev Biol. 2010 Jun 1;342(1):74-84 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:156253 Tateossian H, Hardisty-Hughes RE, Morse S, Romero MR, Hilton H, Dean C, Brown SD, Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant. Pathogenetics. 2009;2(1):5 |
2 | J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521 |
1 | J:278336 Wang W, Chun H, Baek J, Sadik JE, Shirazyan A, Razavi P, Lopez N, Lyons KM, The TGFbeta type I receptor TGFbetaRI functions as an inhibitor of BMP signaling in cartilage. Proc Natl Acad Sci U S A. 2019 Jul 30;116(31):15570-15579 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
Tgfbr2 transforming growth factor, beta receptor II (Synonyms: 1110020H15Rik, TbetaR-II, TbetaRII, TBR-II) | |
Results | Reference |
1 | J:218171 Falix FA, Weeda VB, Labruyere WT, Poncy A, de Waart DR, Hakvoort TB, Lemaigre F, Gaemers IC, Aronson DC, Lamers WH, Hepatic Notch2 deficiency leads to bile duct agenesis perinatally and secondary bile duct formation after weaning. Dev Biol. 2014 Dec 15;396(2):201-13 |
1* | J:75698 Grunder A, Ebel TT, Mallo M, Schwarzkopf G, Shimizu T, Sippel AE, Schrewe H, Nuclear factor I-B (Nfib) deficient mice have severe lung hypoplasia. Mech Dev. 2002 Mar;112(1-2):69-77 |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1* | J:16493 Lawler S, Candia AF, Ebner R, Shum L, Lopez AR, Moses HL, Wright CV, Derynck R, The murine type II TGF-beta receptor has a coincident embryonic expression and binding preference for TGF-beta 1. Development. 1994 Jan;120(1):165-75 |
2* | J:51497 Mariano JM, Montuenga LM, Prentice MA, Cuttitta F, Jakowlew SB, Concurrent and distinct transcription and translation of transforming growth factor-beta type I and type II receptors in rodent embryogenesis. Int J Dev Biol. 1998 Nov;42(8):1125-36 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:160474 Moreno SG, Attali M, Allemand I, Messiaen S, Fouchet P, Coffigny H, Romeo PH, Habert R, TGFbeta signaling in male germ cells regulates gonocyte quiescence and fertility in mice. Dev Biol. 2010 Jun 1;342(1):74-84 |
1* | J:121723 Oka S, Oka K, Xu X, Sasaki T, Bringas P Jr, Chai Y, Cell autonomous requirement for TGF-beta signaling during odontoblast differentiation and dentin matrix formation. Mech Dev. 2007 Jul;124(6):409-15 |
2 | J:134924 Spagnoli A, O'Rear L, Chandler RL, Granero-Molto F, Mortlock DP, Gorska AE, Weis JA, Longobardi L, Chytil A, Shimer K, Moses HL, TGF-beta signaling is essential for joint morphogenesis. J Cell Biol. 2007 Jun 18;177(6):1105-17 |
1 | J:156253 Tateossian H, Hardisty-Hughes RE, Morse S, Romero MR, Hilton H, Dean C, Brown SD, Regulation of TGF-beta signalling by Fbxo11, the gene mutated in the Jeff otitis media mouse mutant. Pathogenetics. 2009;2(1):5 |
2 | J:121629 Tulachan SS, Tei E, Hembree M, Crisera C, Prasadan K, Koizumi M, Shah S, Guo P, Bottinger E, Gittes GK, TGF-beta isoform signaling regulates secondary transition and mesenchymal-induced endocrine development in the embryonic mouse pancreas. Dev Biol. 2007 May 15;305(2):508-521 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1* | J:28712 Wang YQ, Sizeland A, Wang XF, Sassoon D, Restricted expression of type-II TGF beta receptor in murine embryonic development suggests a central role in tissue modeling and CNS patterning. Mech Dev. 1995 Aug;52(2-3):275-89 |
2 | J:283373 Zhang W, Shen Z, Xing Y, Zhao H, Liang Y, Chen J, Zhong X, Shi L, Wan X, Zhou J, Tang S, MiR-106a-5p modulates apoptosis and metabonomics changes by TGF-beta/Smad signaling pathway in cleft palate. Exp Cell Res. 2020 Jan 15;386(2):111734 |
Tgfbr3 transforming growth factor, beta receptor III (Synonyms: 1110036H20Rik, betaglycan, TBRIII) | |
Results | Reference |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1 | J:335167 Lu P, Wu B, Wang Y, Russell M, Liu Y, Bernard DJ, Zheng D, Zhou B, Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis. Dev Cell. 2023 Mar 29; |
2* | J:134998 Sarraj MA, Chua HK, Umbers A, Loveland KL, Findlay JK, Stenvers KL, Differential expression of TGFBR3 (betaglycan) in mouse ovary and testis during gonadogenesis. Growth Factors. 2007 Oct;25(5):334-45 |
1 | J:172391 Walker KA, Sims-Lucas S, Caruana G, Cullen-McEwen L, Li J, Sarraj MA, Bertram JF, Stenvers KL, Betaglycan is required for the establishment of nephron endowment in the mouse. PLoS One. 2011;6(4):e18723 |
Tgif1 TGFB-induced factor homeobox 1 (Synonyms: Tgif) | |
Results | Reference |
1 | J:143264 Satoh S, Watanabe S, TGIF, a homeodomain transcription factor, regulates retinal progenitor cell differentiation. Exp Eye Res. 2008 Dec;87(6):571-9 |
Tgif2 TGFB-induced factor homeobox 2 (Synonyms: 5730599O09Rik, TALE family homeobox) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:143264 Satoh S, Watanabe S, TGIF, a homeodomain transcription factor, regulates retinal progenitor cell differentiation. Exp Eye Res. 2008 Dec;87(6):571-9 |
Tgm1 transglutaminase 1, K polypeptide (Synonyms: 2310004J08Rik, K polypeptide, protein-glutamine-gamma-glutamyltransferase, TGase 1, TGase1, TG K) | |
Results | Reference |
1* | J:214170 Itoh M, Tatsukawa H, Eun-Seo L, Yamanishi K, Kojima S, Hitomi K, Variations in both TG1 and TG2 isozyme-specific in situ activities and protein expressions during mouse embryonic development. J Histochem Cytochem. 2013 Nov;61(11):793-801 |
1 | J:114626 Yu Z, Lin KK, Bhandari A, Spencer JA, Xu X, Wang N, Lu Z, Gill GN, Roop DR, Wertz P, Andersen B, The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Dev Biol. 2006 Nov 1;299(1):122-36 |
Tgm2 transglutaminase 2, C polypeptide (Synonyms: G[a]h, protein-glutamine gamma-glutamyltransferase, TG2, TGase2, TG C, tissue transglutaminase, tTG, tTGas) | |
Results | Reference |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1* | J:214170 Itoh M, Tatsukawa H, Eun-Seo L, Yamanishi K, Kojima S, Hitomi K, Variations in both TG1 and TG2 isozyme-specific in situ activities and protein expressions during mouse embryonic development. J Histochem Cytochem. 2013 Nov;61(11):793-801 |
3* | J:98561 Lee SK, Kim YS, Lee YJ, Lee SS, Song IS, Park SC, Chi JG, Chung SI, Transglutaminase 2 expression in the salivary myoepithelial cells of mouse embryo. Arch Oral Biol. 2005 Mar;50(3):301-8 |
1* | J:279119 Seow BKL, McDougall ARA, Short KL, Wallace MJ, Hooper SB, Cole TJ, Identification of Betamethasone-Regulated Target Genes and Cell Pathways in Fetal Rat Lung Mesenchymal Fibroblasts. Endocrinology. 2019 Aug 1;160(8):1868-1884 |
Tgm3 transglutaminase 3, E polypeptide (Synonyms: TG E, we) | |
Results | Reference |
2* | J:100385 Zhang J, Zhi HY, Ding F, Luo AP, Liu ZH, Transglutaminase 3 expression in C57BL/6J mouse embryo epidermis and the correlation with its differentiation. Cell Res. 2005 Feb;15(2):105-10 |
Tgs1 trimethylguanosine synthase 1 (Synonyms: D4Ertd800e, Ncoa6ip, Pimt) | |
Results | Reference |
3* | J:189008 Jia Y, Viswakarma N, Crawford SE, Sarkar J, Sambasiva Rao M, Karpus WJ, Kanwar YS, Zhu YJ, Reddy JK, Early embryonic lethality of mice with disrupted transcription cofactor PIMT/NCOA6IP/Tgs1 gene. Mech Dev. 2012 Sep;129(9-12):193-207 |
Th tyrosine hydroxylase | |
Results | Reference |
1 | J:185533 Achim K, Peltopuro P, Lahti L, Li J, Salminen M, Partanen J, Distinct developmental origins and regulatory mechanisms for GABAergic neurons associated with dopaminergic nuclei in the ventral mesodiencephalic region. Development. 2012 Jul;139(13):2360-70 |
1* | J:329933 Akkuratova N, Faure L, Kameneva P, Kastriti ME, Adameyko I, Developmental heterogeneity of embryonic neuroendocrine chromaffin cells and their maturation dynamics. Front Endocrinol (Lausanne). 2022;13:1020000 |
1 | J:207519 Anderegg A, Lin HP, Chen JA, Caronia-Brown G, Cherepanova N, Yun B, Joksimovic M, Rock J, Harfe BD, Johnson R, Awatramani R, An Lmx1b-miR135a2 regulatory circuit modulates Wnt1/Wnt signaling and determines the size of the midbrain dopaminergic progenitor pool. PLoS Genet. 2013 Dec;9(12):e1003973 |
2 | J:169444 Armstrong A, Ryu YK, Chieco D, Kuruvilla R, Frizzled3 Is Required for Neurogenesis and Target Innervation during Sympathetic Nervous System Development. J Neurosci. 2011 Feb 16;31(7):2371-81 |
1 | J:316661 Barallobre MJ, Perier C, Bove J, Laguna A, Delabar JM, Vila M, Arbones ML, DYRK1A promotes dopaminergic neuron survival in the developing brain and in a mouse model of Parkinson's disease. Cell Death Dis. 2014 Jun 12;5:e1289 |
1 | J:194255 Baydyuk M, Xie Y, Tessarollo L, Xu B, Midbrain-derived neurotrophins support survival of immature striatal projection neurons. J Neurosci. 2013 Feb 20;33(8):3363-9 |
1 | J:156468 Birgner C, Nordenankar K, Lundblad M, Mendez JA, Smith C, le Greves M, Galter D, Olson L, Fredriksson A, Trudeau LE, Kullander K, Wallen-Mackenzie A, VGLUT2 in dopamine neurons is required for psychostimulant-induced behavioral activation. Proc Natl Acad Sci U S A. 2010 Jan 5;107(1):389-94 |
1 | J:208337 Bodea GO, Spille JH, Abe P, Andersson AS, Acker-Palmer A, Stumm R, Kubitscheck U, Blaess S, Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system. Development. 2014 Feb;141(3):661-73 |
1 | J:175248 Bodmer D, Ascano M, Kuruvilla R, Isoform-specific dephosphorylation of dynamin1 by calcineurin couples neurotrophin receptor endocytosis to axonal growth. Neuron. 2011 Jun 23;70(6):1085-99 |
1 | J:149814 Bodmer D, Levine-Wilkinson S, Richmond A, Hirsh S, Kuruvilla R, Wnt5a mediates nerve growth factor-dependent axonal branching and growth in developing sympathetic neurons. J Neurosci. 2009 Jun 10;29(23):7569-81 |
1 | J:277168 Bohuslavova R, Cerychova R, Papousek F, Olejnickova V, Bartos M, Gorlach A, Kolar F, Sedmera D, Semenza GL, Pavlinkova G, HIF-1alpha is required for development of the sympathetic nervous system. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13414-13423 |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1 | J:297714 Brignani S, Raj DDA, Schmidt ERE, Dudukcu O, Adolfs Y, De Ruiter AA, Rybiczka-Tesulov M, Verhagen MG, van der Meer C, Broekhoven MH, Moreno-Bravo JA, Grossouw LM, Dumontier E, Cloutier JF, Chedotal A, Pasterkamp RJ, Remotely Produced and Axon-Derived Netrin-1 Instructs GABAergic Neuron Migration and Dopaminergic Substantia Nigra Development. Neuron. 2020 Aug 19;107(4):684-702.e9 |
1 | J:51888 Bulfone A, Wang F, Hevner R, Anderson S, Cutforth T, Chen S, Meneses J, Pedersen R, Axel R, Rubenstein JL, An olfactory sensory map develops in the absence of normal projection neurons or GABAergic interneurons. Neuron. 1998 Dec;21(6):1273-82 |
1 | J:210127 Bupesh M, Vicario A, Abellan A, Desfilis E, Medina L, Dynamic expression of tyrosine hydroxylase mRNA and protein in neurons of the striatum and amygdala of mice, and experimental evidence of their multiple embryonic origin. Brain Struct Funct. 2014 May;219(3):751-76 |
1* | J:296652 Chan WH, Gonsalvez DG, Young HM, Southard-Smith EM, Cane KN, Anderson CR, Differences in CART expression and cell cycle behavior discriminate sympathetic neuroblast from chromaffin cell lineages in mouse sympathoadrenal cells. Dev Neurobiol. 2016 Feb;76(2):137-49 |
1* | J:308673 Company V, Andreu-Cervera A, Madrigal MP, Andres B, Almagro-Garcia F, Chedotal A, Lopez-Bendito G, Martinez S, Echevarria D, Moreno-Bravo JA, Puelles E, Netrin 1-Mediated Role of the Substantia Nigra Pars Compacta and Ventral Tegmental Area in the Guidance of the Medial Habenular Axons. Front Cell Dev Biol. 2021;9:682067 |
1 | J:166770 Coppola E, d'Autreaux F, Rijli FM, Brunet JF, Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation. Development. 2010 Dec;137(24):4211-20 |
2* | J:276249 Crerar H, Scott-Solomon E, Bodkin-Clarke C, Andreassi C, Hazbon M, Logie E, Cano-Jaimez M, Gaspari M, Kuruvilla R, Riccio A, Regulation of NGF Signaling by an Axonal Untranslated mRNA. Neuron. 2019 May 8;102(3):553-563.e8 |
1* | J:86516 Dauger S, Pattyn A, Lofaso F, Gaultier C, Goridis C, Gallego J, Brunet JF, Phox2b controls the development of peripheral chemoreceptors and afferent visceral pathways. Development. 2003 Dec;130(26):6635-42 |
1 | J:124043 Deng DR, Djalali S, Holtje M, Grosse G, Stroh T, Voigt I, Kusserow H, Theuring F, Ahnert-Hilger G, Hortnagl H, Embryonic and postnatal development of the serotonergic raphe system and its target regions in 5-HT1A receptor deletion or overexpressing mouse mutants. Neuroscience. 2007 Jun 29;147(2):388-402 |
1* | J:154889 Deschamps C, Faideau M, Jaber M, Gaillard A, Prestoz L, Expression of ephrinA5 during development and potential involvement in the guidance of the mesostriatal pathway. Exp Neurol. 2009 Oct;219(2):466-80 |
1 | J:358820 Dudukcu O, Raj DDA, van de Haar LL, Grossouw LM, Linders LE, Garritsen O, Adolfs Y, van Kronenburg NCH, Broekhoven MH, Kapteijns THW, Meye FJ, Pasterkamp RJ, Molecular diversity and migration of GABAergic neurons in the developing ventral midbrain. iScience. 2024 Nov 15;27(11):111239 |
1 | J:30830 Durbec PL, Larsson-Blomberg LB, Schuchardt A, Costantini F, Pachnis V, Common origin and developmental dependence on c-ret of subsets of enteric and sympathetic neuroblasts. Development. 1996 Jan;122(1):349-58 |
1 | J:98272 Engleka KA, Gitler AD, Zhang M, Zhou DD, High FA, Epstein JA, Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives. Dev Biol. 2005 Apr 15;280(2):396-406 |
1 | J:187343 Erickson CS, Zaitoun I, Haberman KM, Gosain A, Druckenbrod NR, Epstein ML, Sacral neural crest-derived cells enter the aganglionic colon of Ednrb-/- mice along extrinsic nerve fibers. J Comp Neurol. 2012 Feb 15;520(3):620-32 |
1 | J:244596 Furlan A, Dyachuk V, Kastriti ME, Calvo-Enrique L, Abdo H, Hadjab S, Chontorotzea T, Akkuratova N, Usoskin D, Kamenev D, Petersen J, Sunadome K, Memic F, Marklund U, Fried K, Topilko P, Lallemend F, Kharchenko PV, Ernfors P, Adameyko I, Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla. Science. 2017 Jul 07;357(6346) |
1 | J:223161 Gahring LC, Myers E, Palumbos S, Rogers SW, Nicotinic receptor Alpha7 expression during mouse adrenal gland development. PLoS One. 2014;9(8):e103861 |
1 | J:87702 Glebova NO, Ginty DD, Heterogeneous requirement of NGF for sympathetic target innervation in vivo. J Neurosci. 2004 Jan 21;24(3):743-51 |
1 | J:196579 Gonsalvez DG, Cane KN, Landman KA, Enomoto H, Young HM, Anderson CR, Proliferation and cell cycle dynamics in the developing stellate ganglion. J Neurosci. 2013 Apr 3;33(14):5969-79 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1 | J:315113 Hafner R, Bohnenpoll T, Rudat C, Schultheiss TM, Kispert A, Fgfr2 is required for the expansion of the early adrenocortical primordium. Mol Cell Endocrinol. 2015 Sep 15;413:168-77 |
1* | J:137254 Harrison SJ, Parrish M, Monaghan AP, Sall3 is required for the terminal maturation of olfactory glomerular interneurons. J Comp Neurol. 2008 Apr 10;507(5):1780-94 |
1 | J:193109 Hayes L, Ralls S, Wang H, Ahn S, Duration of Shh signaling contributes to mDA neuron diversity. Dev Biol. 2013 Feb 1;374(1):115-26 |
1 | J:253782 Hedlund E, Belnoue L, Theofilopoulos S, Salto C, Bye C, Parish C, Deng Q, Kadkhodaei B, Ericson J, Arenas E, Perlmann T, Simon A, Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors. Sci Rep. 2016 Jun 1;6:26448 |
1 | J:256518 Hegarty SV, Wyatt SL, Howard L, Stappers E, Huylebroeck D, Sullivan AM, O'Keeffe GW, Zeb2 is a negative regulator of midbrain dopaminergic axon growth and target innervation. Sci Rep. 2017 Aug 17;7(1):8568 |
2 | J:332402 Hockman D, Adameyko I, Kaucka M, Barraud P, Otani T, Hunt A, Hartwig AC, Sock E, Waithe D, Franck MCM, Ernfors P, Ehinger S, Howard MJ, Brown N, Reese J, Baker CVH, Striking parallels between carotid body glomus cell and adrenal chromaffin cell development. Dev Biol. 2018 Dec 1;444 Suppl 1(Suppl 1):S308-S324 |
1 | J:189572 Huang CC, Liu C, Yao HH, Investigating the role of adrenal cortex in organization and differentiation of the adrenal medulla in mice. Mol Cell Endocrinol. 2012 Sep 25;361(1-2):165-71 |
1 | J:191801 Huang CC, Shih MC, Hsu NC, Chien Y, Chung BC, Fetal glucocorticoid synthesis is required for development of fetal adrenal medulla and hypothalamus feedback suppression. Endocrinology. 2012 Oct;153(10):4749-56 |
1* | J:163555 Huang CC, Yao HH, Inactivation of Dicer1 in Steroidogenic factor 1-positive cells reveals tissue-specific requirement for Dicer1 in adrenal, testis, and ovary. BMC Dev Biol. 2010;10:66 |
1 | J:199638 Huang T, Hu J, Wang B, Nie Y, Geng J, Cheng L, Tlx3 controls cholinergic transmitter and Peptide phenotypes in a subset of prenatal sympathetic neurons. J Neurosci. 2013 Jun 26;33(26):10667-75 |
2 | J:79390 Huber K, Bruhl B, Guillemot F, Olson EN, Ernsberger U, Unsicker K, Development of chromaffin cells depends on MASH1 function. Development. 2002 Oct;129(20):4729-38 |
1 | J:199593 Huber K, Narasimhan P, Shtukmaster S, Pfeifer D, Evans SM, Sun Y, The LIM-Homeodomain transcription factor Islet-1 is required for the development of sympathetic neurons and adrenal chromaffin cells. Dev Biol. 2013 Aug 15;380(2):286-98 |
1 | J:152424 Jacob J, Storm R, Castro DS, Milton C, Pla P, Guillemot F, Birchmeier C, Briscoe J, Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain. Development. 2009 Jul;136(14):2477-85 |
1 | J:146200 Joksimovic M, Yun BA, Kittappa R, Anderegg AM, Chang WW, Taketo MM, McKay RD, Awatramani RB, Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis. Nat Neurosci. 2009 Feb;12(2):125-31 |
1 | J:308791 Kameneva P, Artemov AV, Kastriti ME, Faure L, Olsen TK, Otte J, Erickson A, Semsch B, Andersson ER, Ratz M, Frisen J, Tischler AS, de Krijger RR, Bouderlique T, Akkuratova N, Vorontsova M, Gusev O, Fried K, Sundstrom E, Mei S, Kogner P, Baryawno N, Kharchenko PV, Adameyko I, Single-cell transcriptomics of human embryos identifies multiple sympathoblast lineages with potential implications for neuroblastoma origin. Nat Genet. 2021 May;53(5):694-706 |
1 | J:84337 Kawano H, Horie M, Honma S, Kawamura K, Takeuchi K, Kimura S, Aberrant trajectory of ascending dopaminergic pathway in mice lacking Nkx2.1. Exp Neurol. 2003 Jul;182(1):103-12 |
1* | J:25959 Kawano H, Ohyama K, Kawamura K, Nagatsu I, Migration of dopaminergic neurons in the embryonic mesencephalon of mice. Brain Res Dev Brain Res. 1995 May 26;86(1-2):101-13 |
1 | J:346372 Kolesova H, Hrabalova P, Bohuslavova R, Abaffy P, Fabriciova V, Sedmera D, Pavlinkova G, Reprogramming of the developing heart by Hif1a-deficient sympathetic system and maternal diabetes exposure. Front Endocrinol (Lausanne). 2024;15:1344074 |
1 | J:153883 Kolk SM, Gunput RA, Tran TS, van den Heuvel DM, Prasad AA, Hellemons AJ, Adolfs Y, Ginty DD, Kolodkin AL, Burbach JP, Smidt MP, Pasterkamp RJ, Semaphorin 3F is a bifunctional guidance cue for dopaminergic axons and controls their fasciculation, channeling, rostral growth, and intracortical targeting. J Neurosci. 2009 Oct 7;29(40):12542-57 |
1 | J:201110 Komada M, Iguchi T, Takeda T, Ishibashi M, Sato M, Smoothened controls cyclin D2 expression and regulates the generation of intermediate progenitors in the developing cortex. Neurosci Lett. 2013 Jun 28;547:87-91 |
1 | J:229533 Kouwenhoven WM, Veenvliet JV, van Hooft JA, van der Heide LP, Smidt MP, Engrailed 1 shapes the dopaminergic and serotonergic landscape through proper isthmic organizer maintenance and function. Biol Open. 2016;5(3):279-88 |
1* | J:231259 Krill KT, Gurdziel K, Heaton JH, Simon DP, Hammer GD, Dicer deficiency reveals microRNAs predicted to control gene expression in the developing adrenal cortex. Mol Endocrinol. 2013 May;27(5):754-68 |
1 | J:222854 Laguna A, Schintu N, Nobre A, Alvarsson A, Volakakis N, Jacobsen JK, Gomez-Galan M, Sopova E, Joodmardi E, Yoshitake T, Deng Q, Kehr J, Ericson J, Svenningsson P, Shupliakov O, Perlmann T, Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease. Nat Neurosci. 2015 Jun;18(6):826-35 |
1 | J:239986 Lahti L, Haugas M, Tikker L, Airavaara M, Voutilainen MH, Anttila J, Kumar S, Inkinen C, Salminen M, Partanen J, Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei. Development. 2016 Feb 01;143(3):516-29 |
1 | J:263715 Lee B, Kim J, An T, Kim S, Patel EM, Raber J, Lee SK, Lee S, Lee JW, Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons. Nat Commun. 2018 May 23;9(1):2026 |
1 | J:237344 Lee B, Lee S, Lee SK, Lee JW, The LIM-homeobox transcription factor Isl1 plays crucial roles in the development of multiple arcuate nucleus neurons. Development. 2016 Oct 15;143(20):3763-3773 |
1 | J:250662 Manousiouthakis E, Mendez M, Garner MC, Exertier P, Makita T, Venous endothelin guides sympathetic innervation of the developing mouse heart. Nat Commun. 2014 May 29;5:3918 |
1* | J:327955 Mapps AA, Boehm E, Beier C, Keenan WT, Langel J, Liu M, Thomsen MB, Hattar S, Zhao H, Tampakakis E, Kuruvilla R, Satellite glia modulate sympathetic neuron survival, activity, and autonomic function. Elife. 2022 Aug 23;11:e74295 |
1 | J:338454 Marfull-Oromi P, Fleitas C, Zammou B, Rocandio D, Ballester-Lurbe B, Terrado J, Perez-Roger I, Espinet C, Egea J, Genetic ablation of the Rho GTPase Rnd3 triggers developmental defects in internal capsule and the globus pallidus formation. J Neurochem. 2021 Jul;158(2):197-216 |
1 | J:293919 Martin-Lopez E, Xu C, Liberia T, Meller SJ, Greer CA, Embryonic and postnatal development of mouse olfactory tubercle. Mol Cell Neurosci. 2019 Jul;98:82-96 |
1 | J:313300 Mesman S, van Hooft JA, Smidt MP, Mest/Peg1 Is Essential for the Development and Maintenance of a SNc Neuronal Subset. Front Mol Neurosci. 2016;9:166 |
1 | J:239291 Metzakopian E, Bouhali K, Alvarez-Saavedra M, Whitsett JA, Picketts DJ, Ang SL, Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells. Development. 2015 Apr 01;142(7):1315-24 |
2 | J:295953 Niu X, Liu L, Wang T, Chuan X, Yu Q, Du M, Gu Y, Wang L, Mapping of Extrinsic Innervation of the Gastrointestinal Tract in the Mouse Embryo. J Neurosci. 2020 Aug 26;40(35):6691-6708 |
1 | J:124270 Ono Y, Nakatani T, Sakamoto Y, Mizuhara E, Minaki Y, Kumai M, Hamaguchi A, Nishimura M, Inoue Y, Hayashi H, Takahashi J, Imai T, Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells. Development. 2007 Sep;134(17):3213-25 |
1 | J:315120 Panman L, Papathanou M, Laguna A, Oosterveen T, Volakakis N, Acampora D, Kurtsdotter I, Yoshitake T, Kehr J, Joodmardi E, Muhr J, Simeone A, Ericson J, Perlmann T, Sox6 and Otx2 control the specification of substantia nigra and ventral tegmental area dopamine neurons. Cell Rep. 2014 Aug 21;8(4):1018-25 |
1 | J:335234 Parveen N, Wang JK, Bhattacharya S, Cuala J, Singh Rajkumar M, Butler AE, Wu X, Shih HP, Georgia SK, Dhawan S, DNA methylation Dependent Restriction of Tyrosine Hydroxylase Contributes to Pancreatic beta-cell Heterogeneity. Diabetes. 2023 Jan 6;72(5):575-89 |
2 | J:228293 Patel A, Yamashita N, Ascano M, Bodmer D, Boehm E, Bodkin-Clarke C, Ryu YK, Kuruvilla R, RCAN1 links impaired neurotrophin trafficking to aberrant development of the sympathetic nervous system in Down syndrome. Nat Commun. 2015;6:10119 |
1 | J:197599 Pitetti JL, Calvel P, Romero Y, Conne B, Truong V, Papaioannou MD, Schaad O, Docquier M, Herrera PL, Wilhelm D, Nef S, Insulin and IGF1 receptors are essential for XX and XY gonadal differentiation and adrenal development in mice. PLoS Genet. 2013;9(1):e1003160 |
1 | J:133489 Qiu F, Jiang H, Xiang M, A comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursors. J Neurosci. 2008 Mar 26;28(13):3392-403 |
1 | J:155760 Rose MF, Ren J, Ahmad KA, Chao HT, Klisch TJ, Flora A, Greer JJ, Zoghbi HY, Math1 is essential for the development of hindbrain neurons critical for perinatal breathing. Neuron. 2009 Nov 12;64(3):341-54 |
1* | J:196291 Ryu YK, Collins SE, Ho HY, Zhao H, Kuruvilla R, An autocrine Wnt5a-Ror signaling loop mediates sympathetic target innervation. Dev Biol. 2013 May 1;377(1):79-89 |
2 | J:361603 Scavuzzo MA, Szlachcic WJ, Hill MC, Ziojla NM, Teaw J, Carlson JC, Tiessen J, Chmielowiec J, Martin JF, Borowiak M, Pancreatic organogenesis mapped through space and time. Exp Mol Med. 2025 Feb;57(1):204-220 |
1 | J:215618 Schmidt ER, Brignani S, Adolfs Y, Lemstra S, Demmers J, Vidaki M, Donahoo AL, Lillevali K, Vasar E, Richards LJ, Karagogeos D, Kolk SM, Pasterkamp RJ, Subdomain-mediated axon-axon signaling and chemoattraction cooperate to regulate afferent innervation of the lateral habenula. Neuron. 2014 Jul 16;83(2):372-87 |
1 | J:198880 Shi M, Hu ZL, Zheng MH, Song NN, Huang Y, Zhao G, Han H, Ding YQ, Notch-Rbpj signaling is required for the development of noradrenergic neurons in the mouse locus coeruleus. J Cell Sci. 2012 Sep 15;125(Pt 18):4320-32 |
1* | J:286599 Song NN, Ma P, Zhang Q, Zhang L, Wang H, Zhang L, Zhu L, He CH, Mao B, Ding YQ, Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199 |
2 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
1 | J:338930 Tarnick J, Elhendawi M, Holland I, Chang Z, Davies JA, Innervation of the developing kidney in vivo and in vitro. Biol Open. 2023 Aug 15;12(8) |
1* | J:137167 Tennese AA, Gee CB, Wevrick R, Loss of the Prader-Willi syndrome protein necdin causes defective migration, axonal outgrowth, and survival of embryonic sympathetic neurons. Dev Dyn. 2008 Jul;237(7):1935-43 |
1 | J:214891 Torigoe M, Yamauchi K, Tamada A, Matsuda I, Aiba A, Castellani V, Murakami F, Role of neuropilin-2 in the ipsilateral growth of midbrain dopaminergic axons. Eur J Neurosci. 2013 May;37(10):1573-83 |
1 | J:277336 Turco AE, Cadena MT, Zhang HL, Sandhu JK, Oakes SR, Chathurvedula T, Peterson RE, Keast JR, Vezina CM, A temporal and spatial map of axons in developing mouse prostate. Histochem Cell Biol. 2019 Jul;152(1):35-45 |
1* | J:199400 van den Heuvel DM, Hellemons AJ, Pasterkamp RJ, Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain. PLoS One. 2013;8(2):e55828 |
1* | J:195264 Vincentz JW, Firulli BA, Lin A, Spicer DB, Howard MJ, Firulli AB, Twist1 Controls a Cell-Specification Switch Governing Cell Fate Decisions within the Cardiac Neural Crest. PLoS Genet. 2013 Mar;9(3):e1003405 |
1 | J:64211 Vitalis T, Cases O, Engelkamp D, Verney C, Price DJ, Defect of tyrosine hydroxylase-immunoreactive neurons in the brains of mice lacking the transcription factor Pax6. J Neurosci. 2000 Sep 1;20(17):6501-16 |
1 | J:161774 Wang S, Turner EE, Expression of dopamine pathway genes in the midbrain is independent of known ETS transcription factor activity. J Neurosci. 2010 Jul 7;30(27):9224-7 |
1 | J:297686 Watanabe-Asaka T, Hayashi M, Engel JD, Kawai Y, Moriguchi T, GATA2 functions in adrenal chromaffin cells. Genes Cells. 2020 Sep;25(9):607-614 |
1 | J:242450 Yang Q, Liu S, Yin M, Yin Y, Zhou G, Zhou J, Ebf2 is required for development of dopamine neurons in the midbrain periaqueductal gray matter of mouse. Dev Neurobiol. 2015 Nov;75(11):1282-94 |
1 | J:311873 Ye S, Yang N, Lu T, Wu T, Wang L, Pan YH, Cao X, Yuan X, Wisniewski T, Dang S, Zhang W, Adamts18 modulates the development of the aortic arch and common carotid artery. iScience. 2021 Jun 25;24(6):102672 |
1 | J:312485 Zhang Q, Zhang L, Huang Y, Ma P, Mao B, Ding YQ, Song NN, Satb2 regulates the development of dopaminergic neurons in the arcuate nucleus by Dlx1. Cell Death Dis. 2021 Sep 25;12(10):879 |
2 | J:302950 Zhang Y, Granholm AC, Huh K, Shan L, Diaz-Ruiz O, Malik N, Olson L, Hoffer BJ, Lupica CR, Hoffman AF, Backman CM, PTEN deletion enhances survival, neurite outgrowth and function of dopamine neuron grafts to MitoPark mice. Brain. 2012 Sep;135(Pt 9):2736-49 |
1 | J:143763 Zhang Y, Singh MK, Degenhardt KR, Lu MM, Bennett J, Yoshida Y, Epstein JA, Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects. Dev Biol. 2009 Jan 1;325(1):82-93 |
Thap11 THAP domain containing 11 (Synonyms: 2810036E22Rik, CTG-B45d, Ronin) | |
Results | Reference |
1 | J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134 |
2 | J:301859 Poche RA, Zhang M, Rueda EM, Tong X, McElwee ML, Wong L, Hsu CW, Dejosez M, Burns AR, Fox DA, Martin JF, Zwaka TP, Dickinson ME, RONIN Is an Essential Transcriptional Regulator of Genes Required for Mitochondrial Function in the Developing Retina. Cell Rep. 2016 Feb 23;14(7):1684-1697 |
Thbd thrombomodulin (Synonyms: CD141, TM) | |
Results | Reference |
1 | J:14532 Ford VA, Wilkinson JE, Kennel SJ, Thrombomodulin distribution during murine development. Roux Arch Dev Biol. 1993 Aug;202(6):364-370 |
Thbs1 thrombospondin 1 (Synonyms: tbsp1, Thbs-1, TSP-1, TSP1) | |
Results | Reference |
2* | J:14410 Iruela-Arispe ML, Liska DJ, Sage EH, Bornstein P, Differential expression of thrombospondin 1, 2, and 3 during murine development. Dev Dyn. 1993 May;197(1):40-56 |
1* | J:1991 Laherty CD, O'Rourke K, Wolf FW, Katz R, Seldin MF, Dixit VM, Characterization of mouse thrombospondin 2 sequence and expression during cell growth and development. J Biol Chem. 1992 Feb 15;267(5):3274-81 |
1* | J:91885 Saika S, Miyamoto T, Ishida I, Barbour WK, Ohnishi Y, Ooshima A, Accumulation of thrombospondin-1 in post-operative capsular fibrosis and its down-regulation in lens cells during lens fiber formation. Exp Eye Res. 2004 Aug;79(2):147-56 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Thbs2 thrombospondin 2 (Synonyms: Thbs-2, Thrombospondin-2, TSP2) | |
Results | Reference |
2* | J:14410 Iruela-Arispe ML, Liska DJ, Sage EH, Bornstein P, Differential expression of thrombospondin 1, 2, and 3 during murine development. Dev Dyn. 1993 May;197(1):40-56 |
1* | J:1991 Laherty CD, O'Rourke K, Wolf FW, Katz R, Seldin MF, Dixit VM, Characterization of mouse thrombospondin 2 sequence and expression during cell growth and development. J Biol Chem. 1992 Feb 15;267(5):3274-81 |
Thbs3 thrombospondin 3 (Synonyms: Thbs-3, TSP3) | |
Results | Reference |
2* | J:14410 Iruela-Arispe ML, Liska DJ, Sage EH, Bornstein P, Differential expression of thrombospondin 1, 2, and 3 during murine development. Dev Dyn. 1993 May;197(1):40-56 |
2* | J:16883 Qabar AN, Lin Z, Wolf FW, O'Shea KS, Lawler J, Dixit VM, Thrombospondin 3 is a developmentally regulated heparin binding protein. J Biol Chem. 1994 Jan 14;269(2):1262-9 |
Thbs4 thrombospondin 4 (Synonyms: TSP-4, TSP4) | |
Results | Reference |
1 | J:333369 Lipp SN, Jacobson KR, Colling HA, Tuttle TG, Miles DT, McCreery KP, Calve S, Mechanical loading is required for initiation of extracellular matrix deposition at the developing murine myotendinous junction. Matrix Biol. 2023 Feb;116:28-48 |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Thoc2l THO complex subunit 2-like (Synonyms: BC005561, Gm3179) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Thpo thrombopoietin (Synonyms: Mpllg, myeloproliferative leukemia virus oncogene ligand, TPO, TPO-1, TPO-2, TPO-3, TPO-4) | |
Results | Reference |
1* | J:159378 Chou S, Lodish HF, Fetal liver hepatic progenitors are supportive stromal cells for hematopoietic stem cells. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7799-804 |
Thra thyroid hormone receptor alpha (Synonyms: 6430529J03Rik, c-erbAalpha, Erba, Nr1a1, Rvr, T3R[a], T3Ralpha, Thra1, Thra2, TR alpha 1, TR alpha 2) | |
Results | Reference |
1 | J:222168 Huang CC, Kraft C, Moy N, Ng L, Forrest D, A Novel Population of Inner Cortical Cells in the Adrenal Gland That Displays Sexually Dimorphic Expression of Thyroid Hormone Receptor-beta1. Endocrinology. 2015 Jun;156(6):2338-48 |
1 | J:178367 Slamon DJ, Cline MJ, Expression of cellular oncogenes during embryonic and fetal development of the mouse. Proc Natl Acad Sci U S A. 1984 Nov;81(22):7141-5 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Thrap3 thyroid hormone receptor associated protein 3 (Synonyms: 9330151F09Rik, B230333E16Rik, Trap150) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:317562 Sono T, Akiyama H, Miura S, Deng JM, Shukunami C, Hiraki Y, Tsushima Y, Azuma Y, Behringer RR, Matsuda S, THRAP3 interacts with and inhibits the transcriptional activity of SOX9 during chondrogenesis. J Bone Miner Metab. 2018 Jul;36(4):410-419 |
Thrb thyroid hormone receptor beta (Synonyms: c-erbAbeta, Nr1a2, T3R[b], T3Rbeta, Thrb1, Thrb2, TR beta) | |
Results | Reference |
1 | J:287985 Bosze B, Moon MS, Kageyama R, Brown NL, Simultaneous Requirements for Hes1 in Retinal Neurogenesis and Optic Cup-Stalk Boundary Maintenance. J Neurosci. 2020 Feb 12;40(7):1501-1513 |
1 | J:341148 Bosze B, Suarez-Navarro J, Cajias I, Brzezinski Iv JA, Brown NL, Notch pathway mutants do not equivalently perturb mouse embryonic retinal development. PLoS Genet. 2023 Sep;19(9):e1010928 |
1 | J:314893 Emerson MM, Surzenko N, Goetz JJ, Trimarchi J, Cepko CL, Otx2 and Onecut1 promote the fates of cone photoreceptors and horizontal cells and repress rod photoreceptors. Dev Cell. 2013 Jul 15;26(1):59-72 |
1 | J:222168 Huang CC, Kraft C, Moy N, Ng L, Forrest D, A Novel Population of Inner Cortical Cells in the Adrenal Gland That Displays Sexually Dimorphic Expression of Thyroid Hormone Receptor-beta1. Endocrinology. 2015 Jun;156(6):2338-48 |
1 | J:285747 Liu S, Liu X, Li S, Huang X, Qian H, Jin K, Xiang M, Foxn4 is a temporal identity factor conferring mid/late-early retinal competence and involved in retinal synaptogenesis. Proc Natl Acad Sci U S A. 2020 Mar 3;117(9):5016-5027 |
1 | J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77 |
1 | J:309104 Zheng MH, Shi M, Pei Z, Gao F, Han H, Ding YQ, The transcription factor RBP-J is essential for retinal cell differentiation and lamination. Mol Brain. 2009 Dec 18;2:38 |
Thrsp thyroid hormone responsive (Synonyms: S14, Spot 14) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Thsd4 thrombospondin, type I, domain containing 4 (Synonyms: ADAMTSL6, B230114P05Rik) | |
Results | Reference |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:160041 Tsutsui K, Manabe R, Yamada T, Nakano I, Oguri Y, Keene DR, Sengle G, Sakai LY, Sekiguchi K, ADAMTSL-6 is a novel extracellular matrix protein that binds to fibrillin-1 and promotes fibrillin-1 fibril formation. J Biol Chem. 2010 Feb 12;285(7):4870-82 |
Thy1 thymus cell antigen 1, theta (Synonyms: CD90, T25, theta, Thy-1, Thy1.1, Thy 1.2, Thy-1.2, Thy1.2) | |
Results | Reference |
1 | J:186083 Calderon L, Boehm T, Synergistic, context-dependent, and hierarchical functions of epithelial components in thymic microenvironments. Cell. 2012 Mar 30;149(1):159-72 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1 | J:94593 Inaki K, Nishimura S, Nakashiba T, Itohara S, Yoshihara Y, Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules. J Comp Neurol. 2004 Nov 15;479(3):243-56 |
1* | J:114661 Lyu YL, Lin CP, Azarova AM, Cai L, Wang JC, Liu LF, Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Mol Cell Biol. 2006 Nov;26(21):7929-41 |
2 | J:32950 Xue GP, Calvert RA, Morris RJ, Expression of the neuronal surface glycoprotein Thy-1 is under post-transcriptional control, and is spatially regulated, in the developing olfactory system. Development. 1990 Aug;109(4):851-64 |
Tia1 cytotoxic granule-associated RNA binding protein 1 (Synonyms: 2310050N03Rik, mTIA-1) | |
Results | Reference |
1* | J:36355 Lowin B, French L, Martinou JC, Tschopp J, Expression of the CTL-associated protein TIA-1 during murine embryogenesis. J Immunol. 1996 Aug 15;157(4):1448-54 |
Tial1 Tia1 cytotoxic granule-associated RNA binding protein-like 1 (Synonyms: 5330433G13Rik, mTIAR, TIAR) | |
Results | Reference |
1 | J:158581 Barrios F, Filipponi D, Pellegrini M, Paronetto MP, Di Siena S, Geremia R, Rossi P, De Felici M, Jannini EA, Dolci S, Opposing effects of retinoic acid and FGF9 on Nanos2 expression and meiotic entry of mouse germ cells. J Cell Sci. 2010 Mar 15;123(Pt 6):871-80 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Tiam1 T cell lymphoma invasion and metastasis 1 (Synonyms: D16Ium10, D16Ium10e) | |
Results | Reference |
1 | J:273200 Landin Malt A, Dailey Z, Holbrook-Rasmussen J, Zheng Y, Hogan A, Du Q, Lu X, Par3 is essential for the establishment of planar cell polarity of inner ear hair cells. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4999-5008 |
2 | J:171513 Tian Y, Zhang Y, Hurd L, Hannenhalli S, Liu F, Lu MM, Morrisey EE, Regulation of lung endoderm progenitor cell behavior by miR302/367. Development. 2011 Apr;138(7):1235-45 |
Tiam2 T cell lymphoma invasion and metastasis 2 (Synonyms: 3000002F19Rik, mKIAA2016, STEF) | |
Results | Reference |
1* | J:55621 Hoshino M, Sone M, Fukata M, Kuroda S, Kaibuchi K, Nabeshima Y, Hama C, Identification of the stef gene that encodes a novel guanine nucleotide exchange factor specific for Rac1. J Biol Chem. 1999 Jun 18;274(25):17837-44 |
Tie1 tyrosine kinase with immunoglobulin-like and EGF-like domains 1 (Synonyms: D430008P04Rik, TIE, tie-1) | |
Results | Reference |
1 | J:71816 Ayadi A, Zheng H, Sobieszczuk P, Buchwalter G, Moerman P, Alitalo K, Wasylyk B, Net-targeted mutant mice develop a vascular phenotype and up-regulate egr-1. EMBO J. 2001 Sep 17;20(18):5139-52 |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1 | J:262023 Morooka N, Futaki S, Sato-Nishiuchi R, Nishino M, Totani Y, Shimono C, Nakano I, Nakajima H, Mochizuki N, Sekiguchi K, Polydom Is an Extracellular Matrix Protein Involved in Lymphatic Vessel Remodeling. Circ Res. 2017 Apr 14;120(8):1276-1288 |
2 | J:281274 Qu X, Violette K, Sewell-Loftin MK, Soslow J, Saint-Jean L, Hinton RB, Merryman WD, Baldwin HS, Loss of flow responsive Tie1 results in ImpairedAortic valve remodeling. Dev Biol. 2019 Nov 1;455(1):73-84 |
1 | J:219810 Qu X, Zhou B, Scott Baldwin H, Tie1 is required for lymphatic valve and collecting vessel development. Dev Biol. 2015 Mar 1;399(1):117-28 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1* | J:57001 Yuan HT, Suri C, Yancopoulos GD, Woolf AS, Expression of angiopoietin-1, angiopoietin-2, and the Tie-2 receptor tyrosine kinase during mouse kidney maturation. J Am Soc Nephrol. 1999 Aug;10(8):1722-36 |
Timm23 translocase of inner mitochondrial membrane 23 (Synonyms: MGC:46821, Tim23) | |
Results | Reference |
1* | J:305946 Xu M, Yao J, Shi Y, Yi H, Zhao W, Lin X, Yang Z, The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026 |
Timp1 tissue inhibitor of metalloproteinase 1 (Synonyms: Clgi, MGC:7143, TIMP-1) | |
Results | Reference |
1* | J:14524 Clauss IM, Gravallese EM, Darling JM, Shapiro F, Glimcher MJ, Glimcher LH, In situ hybridization studies suggest a role for the basic region-leucine zipper protein hXBP-1 in exocrine gland and skeletal development during mouse embryogenesis. Dev Dyn. 1993 Jun;197(2):146-56 |
1* | J:151001 Flenniken AM, Williams BR, Developmental expression of the endogenous TIMP gene and a TIMP-lacZ fusion gene in transgenic mice. Genes Dev. 1990 Jul;4(7):1094-106 |
1* | J:74063 Joronen K, Salminen H, Glumoff V, Savontaus M, Vuorio E, Temporospatial expression of tissue inhibitors of matrix metalloproteinases-1, -2 and -3 during development, growth and aging of the mouse skeleton. Histochem Cell Biol. 2000 Aug;114(2):157-65 |
2 | J:35125 Nomura S, Hogan BL, Wills AJ, Heath JK, Edwards DR, Developmental expression of tissue inhibitor of metalloproteinase (TIMP) RNA. Development. 1989 Mar;105(3):575-83 |
2* | J:273625 Takahashi M, Fujikawa K, Angammana R, Shibata S, An in situ hybridization study of MMP-2, -9, -13, -14, TIMP-1, and -2 mRNA in fetal mouse mandibular condylar cartilage as compared with limb bud cartilage. Gene Expr Patterns. 2019 Feb 27;32:1-11 |
2* | J:53323 Teesalu T, Masson R, Basset P, Blasi F, Talarico D, Expression of matrix metalloproteinases during murine chorioallantoic placenta maturation. Dev Dyn. 1999 Mar;214(3):248-58 |
2 | J:85488 Yoshiba N, Yoshiba K, Stoetzel C, Perrin-Schmitt F, Cam Y, Ruch JV, Lesot H, Temporospatial gene expression and protein localization of matrix metalloproteinases and their inhibitors during mouse molar tooth development. Dev Dyn. 2003 Sep;228(1):105-12 |
Timp2 tissue inhibitor of metalloproteinase 2 (Synonyms: D11Bwg1104e, Timp-2, TIMP-2) | |
Results | Reference |
1* | J:42593 Blavier L, DeClerck YA, Tissue inhibitor of metalloproteinases-2 is expressed in the interstitial matrix in adult mouse organs and during embryonic development. Mol Biol Cell. 1997 Aug;8(8):1513-27 |
1* | J:74063 Joronen K, Salminen H, Glumoff V, Savontaus M, Vuorio E, Temporospatial expression of tissue inhibitors of matrix metalloproteinases-1, -2 and -3 during development, growth and aging of the mouse skeleton. Histochem Cell Biol. 2000 Aug;114(2):157-65 |
2* | J:273625 Takahashi M, Fujikawa K, Angammana R, Shibata S, An in situ hybridization study of MMP-2, -9, -13, -14, TIMP-1, and -2 mRNA in fetal mouse mandibular condylar cartilage as compared with limb bud cartilage. Gene Expr Patterns. 2019 Feb 27;32:1-11 |
2* | J:53323 Teesalu T, Masson R, Basset P, Blasi F, Talarico D, Expression of matrix metalloproteinases during murine chorioallantoic placenta maturation. Dev Dyn. 1999 Mar;214(3):248-58 |
2 | J:85488 Yoshiba N, Yoshiba K, Stoetzel C, Perrin-Schmitt F, Cam Y, Ruch JV, Lesot H, Temporospatial gene expression and protein localization of matrix metalloproteinases and their inhibitors during mouse molar tooth development. Dev Dyn. 2003 Sep;228(1):105-12 |
Timp3 tissue inhibitor of metalloproteinase 3 (Synonyms: Timp-3) | |
Results | Reference |
1 | J:19451 Apte SS, Hayashi K, Seldin MF, Mattei MG, Hayashi M, Olsen BR, Gene encoding a novel murine tissue inhibitor of metalloproteinases (TIMP), TIMP-3, is expressed in developing mouse epithelia, cartilage, and muscle, and is located on mouse chromosome 10. Dev Dyn. 1994 Jul;200(3):177-97 |
1* | J:42593 Blavier L, DeClerck YA, Tissue inhibitor of metalloproteinases-2 is expressed in the interstitial matrix in adult mouse organs and during embryonic development. Mol Biol Cell. 1997 Aug;8(8):1513-27 |
1* | J:74063 Joronen K, Salminen H, Glumoff V, Savontaus M, Vuorio E, Temporospatial expression of tissue inhibitors of matrix metalloproteinases-1, -2 and -3 during development, growth and aging of the mouse skeleton. Histochem Cell Biol. 2000 Aug;114(2):157-65 |
2* | J:273625 Takahashi M, Fujikawa K, Angammana R, Shibata S, An in situ hybridization study of MMP-2, -9, -13, -14, TIMP-1, and -2 mRNA in fetal mouse mandibular condylar cartilage as compared with limb bud cartilage. Gene Expr Patterns. 2019 Feb 27;32:1-11 |
2* | J:53323 Teesalu T, Masson R, Basset P, Blasi F, Talarico D, Expression of matrix metalloproteinases during murine chorioallantoic placenta maturation. Dev Dyn. 1999 Mar;214(3):248-58 |
2 | J:85488 Yoshiba N, Yoshiba K, Stoetzel C, Perrin-Schmitt F, Cam Y, Ruch JV, Lesot H, Temporospatial gene expression and protein localization of matrix metalloproteinases and their inhibitors during mouse molar tooth development. Dev Dyn. 2003 Sep;228(1):105-12 |
Tiparp TCDD-inducible poly(ADP-ribose) polymerase (Synonyms: DDF1, PARP-7, PARP7) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Tjp1 tight junction protein 1 (Synonyms: ZO-1, ZO1) | |
Results | Reference |
1 | J:228518 Arya P, Rainey MA, Bhattacharyya S, Mohapatra BC, George M, Kuracha MR, Storck MD, Band V, Govindarajan V, Band H, The endocytic recycling regulatory protein EHD1 Is required for ocular lens development. Dev Biol. 2015 Dec 1;408(1):41-55 |
1 | J:253618 Bonney S, Siegenthaler JA, Differential Effects of Retinoic Acid Concentrations in Regulating Blood-Brain Barrier Properties. eNeuro. 2017 May-Jun;4(3):ENEURO.0378-16.2017 |
1 | J:196836 Cammas L, Wolfe J, Choi SY, Dedhar S, Beggs HE, Integrin-linked kinase deletion in the developing lens leads to capsule rupture, impaired fiber migration and non-apoptotic epithelial cell death. Invest Ophthalmol Vis Sci. 2012;53(6):3067-81 |
1 | J:254639 Chen L, Martino V, Dombkowski A, Williams T, West-Mays J, Gage PJ, AP-2beta Is a Downstream Effector of PITX2 Required to Specify Endothelium and Establish Angiogenic Privilege During Corneal Development. Invest Ophthalmol Vis Sci. 2016 Mar;57(3):1072-81 |
1 | J:145627 Devenport D, Fuchs E, Planar polarization in embryonic epidermis orchestrates global asymmetric morphogenesis of hair follicles. Nat Cell Biol. 2008 Nov;10(11):1257-68 |
1 | J:242328 Foerster P, Daclin M, Asm S, Faucourt M, Boletta A, Genovesio A, Spassky N, mTORC1 signaling and primary cilia are required for brain ventricle morphogenesis. Development. 2017 Jan 15;144(2):201-210 |
1 | J:321161 Gerner L, Youssef G, O'Shaughnessy RF, The protein phosphatase 2A regulatory subunit Ppp2r2a is required for Connexin-43 dephosphorlyation during epidermal barrier acquisition. Exp Dermatol. 2013 Nov;22(11):754-6 |
1* | J:93085 Hashizume A, Ueno T, Furuse M, Tsukita S, Nakanishi Y, Hieda Y, Expression patterns of claudin family of tight junction membrane proteins in developing mouse submandibular gland. Dev Dyn. 2004 Oct;231(2):425-31 |
1* | J:156021 Hick AC, van Eyll JM, Cordi S, Forez C, Passante L, Kohara H, Nagasawa T, Vanderhaeghen P, Courtoy PJ, Rousseau GG, Lemaigre FP, Pierreux CE, Mechanism of primitive duct formation in the pancreas and submandibular glands: a role for SDF-1. BMC Dev Biol. 2009;9:66 |
1 | J:317816 Ibarretxe G, Aurrekoetxea M, Crende O, Badiola I, Jimenez-Rojo L, Nakamura T, Yamada Y, Unda F, Epiprofin/Sp6 regulates Wnt-BMP signaling and the establishment of cellular junctions during the bell stage of tooth development. Cell Tissue Res. 2012 Oct;350(1):95-107 |
1 | J:197573 Itoh Y, Moriyama Y, Hasegawa T, Endo TA, Toyoda T, Gotoh Y, Scratch regulates neuronal migration onset via an epithelial-mesenchymal transition-like mechanism. Nat Neurosci. 2013 Apr;16(4):416-25 |
1 | J:334107 Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J, Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice. Hum Mol Genet. 2022 Oct 10;31(20):3504-3520 |
2 | J:173588 Kanazawa T, Ichii O, Otsuka S, Namiki Y, Hashimoto Y, Kon Y, Hepatocyte nuclear factor 4 alpha is associated with mesenchymal-epithelial transition in developing kidneys of C57BL/6 mice. J Vet Med Sci. 2011 May;73(5):601-7 |
1* | J:171566 Kim E, Hyrc KL, Speck J, Lundberg YW, Salles FT, Kachar B, Goldberg MP, Warchol ME, Ornitz DM, Regulation of cellular calcium in vestibular supporting cells by otopetrin 1. J Neurophysiol. 2010 Dec;104(6):3439-50 |
1* | J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347 |
1 | J:306060 Kindt KS, Akturk A, Jarysta A, Day M, Beirl A, Flonard M, Tarchini B, EMX2-GPR156-Galphai reverses hair cell orientation in mechanosensory epithelia. Nat Commun. 2021 May 17;12(1):2861 |
1 | J:266265 Kishimoto K, Tamura M, Nishita M, Minami Y, Yamaoka A, Abe T, Shigeta M, Morimoto M, Synchronized mesenchymal cell polarization and differentiation shape the formation of the murine trachea and esophagus. Nat Commun. 2018 Jul 19;9(1):2816 |
1 | J:270927 Kridsada K, Niu J, Haldipur P, Wang Z, Ding L, Li JJ, Lindgren AG, Herrera E, Thomas GM, Chizhikov VV, Millen KJ, Luo W, Roof Plate-Derived Radial Glial-like Cells Support Developmental Growth of Rapidly Adapting Mechanoreceptor Ascending Axons. Cell Rep. 2018 Jun 5;23(10):2928-2941 |
1 | J:317151 Lavado A, Gangwar R, Pare J, Wan S, Fan Y, Cao X, YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development. Dev Biol. 2021 Dec;480:39-49 |
1 | J:261049 Leone DP, Srinivasan K, Brakebusch C, McConnell SK, The rho GTPase Rac1 is required for proliferation and survival of progenitors in the developing forebrain. Dev Neurobiol. 2010 Aug;70(9):659-78 |
1 | J:246153 Logan CM, Rajakaruna S, Bowen C, Radice GL, Robinson ML, Menko AS, N-cadherin regulates signaling mechanisms required for lens fiber cell elongation and lens morphogenesis. Dev Biol. 2017 Aug 01;428(1):118-134 |
1* | J:218202 Mellas RE, Kim H, Osinski J, Sadibasic S, Gronostajski RM, Cho M, Baker OJ, NFIB Regulates Embryonic Development of Submandibular Glands. J Dent Res. 2015 Feb;94(2):312-9 |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
1* | J:107229 Ohta H, Adachi H, Inaba M, Developmental changes in the expression of tight junction protein claudins in murine metanephroi and embryonic kidneys. J Vet Med Sci. 2006 Feb;68(2):149-55 |
1 | J:317613 Patnaik SR, Kretschmer V, Brucker L, Schneider S, Volz AK, Oancea-Castillo LDR, May-Simera HL, Bardet-Biedl Syndrome proteins regulate cilia disassembly during tissue maturation. Cell Mol Life Sci. 2019 Feb;76(4):757-775 |
1 | J:256217 Rubsam M, Mertz AF, Kubo A, Marg S, Jungst C, Goranci-Buzhala G, Schauss AC, Horsley V, Dufresne ER, Moser M, Ziegler W, Amagai M, Wickstrom SA, Niessen CM, E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning. Nat Commun. 2017 Nov 1;8(1):1250 |
1 | J:213479 Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, Yoshida N, PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Cereb Cortex. 2013 Aug;23(8):1824-35 |
1 | J:206876 Song JY, Park R, Kim JY, Hughes L, Lu L, Kim S, Johnson RL, Cho SH, Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev Biol. 2014 Feb 15;386(2):281-90 |
1 | J:154910 Sugiyama Y, Akimoto K, Robinson ML, Ohno S, Quinlan RA, A cell polarity protein aPKClambda is required for eye lens formation and growth. Dev Biol. 2009 Dec 15;336(2):246-56 |
1 | J:343554 Sun Q, Li J, Ma J, Zheng Y, Ju R, Li X, Ren X, Huang L, Chen R, Tan X, Luo L, JAM-C Is Important for Lens Epithelial Cell Proliferation and Lens Fiber Maturation in Murine Lens Development. Invest Ophthalmol Vis Sci. 2023 Dec 1;64(15):15 |
1 | J:214064 Tarchini B, Jolicoeur C, Cayouette M, A molecular blueprint at the apical surface establishes planar asymmetry in cochlear hair cells. Dev Cell. 2013 Oct 14;27(1):88-102 |
1 | J:302296 Vong KI, Ma TC, Li B, Leung TCN, Nong W, Ngai SM, Hui JHL, Jiang L, Kwan KM, SOX9-COL9A3-dependent regulation of choroid plexus epithelial polarity governs blood-cerebrospinal fluid barrier integrity. Proc Natl Acad Sci U S A. 2021 Feb 9;118(6):e2009568118 |
1* | J:169193 Walsh T, Pierce SB, Lenz DR, Brownstein Z, Dagan-Rosenfeld O, Shahin H, Roeb W, McCarthy S, Nord AS, Gordon CR, Ben-Neriah Z, Sebat J, Kanaan M, Lee MK, Frydman M, King MC, Avraham KB, Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51. Am J Hum Genet. 2010 Jul 9;87(1):101-9 |
1 | J:199582 Youssef G, Gerner L, Naeem AS, Ralph O, Ono M, O'Neill CA, O'Shaughnessy RF, Rab3Gap1 mediates exocytosis of Claudin-1 and tight junction formation during epidermal barrier acquisition. Dev Biol. 2013 Aug 15;380(2):274-85 |
1 | J:125580 Zhang L, Deng M, Kao CW, Kao WW, Xia Y, MEK kinase 1 regulates c-Jun phosphorylation in the control of corneal morphogenesis. Mol Vis. 2003 Nov 3;9:584-93 |
Tjp2 tight junction protein 2 (Synonyms: ZO-2) | |
Results | Reference |
1 | J:173588 Kanazawa T, Ichii O, Otsuka S, Namiki Y, Hashimoto Y, Kon Y, Hepatocyte nuclear factor 4 alpha is associated with mesenchymal-epithelial transition in developing kidneys of C57BL/6 mice. J Vet Med Sci. 2011 May;73(5):601-7 |
2* | J:169193 Walsh T, Pierce SB, Lenz DR, Brownstein Z, Dagan-Rosenfeld O, Shahin H, Roeb W, McCarthy S, Nord AS, Gordon CR, Ben-Neriah Z, Sebat J, Kanaan M, Lee MK, Frydman M, King MC, Avraham KB, Genomic duplication and overexpression of TJP2/ZO-2 leads to altered expression of apoptosis genes in progressive nonsyndromic hearing loss DFNA51. Am J Hum Genet. 2010 Jul 9;87(1):101-9 |
Tkt transketolase (Synonyms: p68) | |
Results | Reference |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Tle1 transducin-like enhancer of split 1 (Synonyms: C230057C06Rik, Estm14, Grg1, Tle4l) | |
Results | Reference |
1 | J:60107 Allen T, Lobe CG, A comparison of Notch, Hes and Grg expression during murine embryonic and post-natal development. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):687-708 |
1* | J:73085 Dasen JS, Barbera JP, Herman TS, Connell SO, Olson L, Ju B, Tollkuhn J, Baek SH, Rose DW, Rosenfeld MG, Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 1;15(23):3193-207 |
1* | J:29935 Dehni G, Liu Y, Husain J, Stifani S, TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination. Mech Dev. 1995 Nov;53(3):369-81 |
1* | J:47495 Yao J, Liu Y, Husain J, Lo R, Palaparti A, Henderson J, Stifani S, Combinatorial expression patterns of individual TLE proteins during cell determination and differentiation suggest non-redundant functions for mammalian homologs of Drosophila Groucho. Dev Growth Differ. 1998 Apr;40(2):133-46 |
Tle3 transducin-like enhancer of split 3 (Synonyms: 2610103N05Rik, ESG, Grg3a, Grg3b, mKIAA1547) | |
Results | Reference |
1 | J:60107 Allen T, Lobe CG, A comparison of Notch, Hes and Grg expression during murine embryonic and post-natal development. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):687-708 |
1 | J:86317 Brinkmeier ML, Potok MA, Cha KB, Gridley T, Stifani S, Meeldijk J, Clevers H, Camper SA, TCF and Groucho-related genes influence pituitary growth and development. Mol Endocrinol. 2003 Nov;17(11):2152-61 |
1* | J:29935 Dehni G, Liu Y, Husain J, Stifani S, TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination. Mech Dev. 1995 Nov;53(3):369-81 |
1 | J:119914 Doyle MJ, Loomis ZL, Sussel L, Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet. Development. 2007 Feb;134(3):515-23 |
1* | J:130185 Ellsworth BS, Butts DL, Camper SA, Mechanisms underlying pituitary hypoplasia and failed cell specification in Lhx3-deficient mice. Dev Biol. 2008 Jan 1;313(1):118-29 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1* | J:35621 Koop KE, MacDonald LM, Lobe CG, Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development. Mech Dev. 1996 Sep;59(1):73-87 |
1* | J:37523 Leon C, Lobe CG, Grg3, a murine Groucho-related gene, is expressed in the developing nervous system and in mesenchyme-induced epithelial structures. Dev Dyn. 1997 Jan;208(1):11-24 |
Tle4 transducin-like enhancer of split 4 (Synonyms: 5730411M05Rik, Bce1, ESTM13, ESTM14, Grg4) | |
Results | Reference |
1* | J:348861 Aberle T, Walter A, Piefke S, Hillgartner S, Wust HM, Wegner M, Kuspert M, Sox10 Activity and the Timing of Schwann Cell Differentiation Are Controlled by a Tle4-Dependent Negative Feedback Loop. Int J Mol Sci. 2024 May 11;25(10) |
1 | J:60107 Allen T, Lobe CG, A comparison of Notch, Hes and Grg expression during murine embryonic and post-natal development. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):687-708 |
1 | J:86317 Brinkmeier ML, Potok MA, Cha KB, Gridley T, Stifani S, Meeldijk J, Clevers H, Camper SA, TCF and Groucho-related genes influence pituitary growth and development. Mol Endocrinol. 2003 Nov;17(11):2152-61 |
1* | J:35621 Koop KE, MacDonald LM, Lobe CG, Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development. Mech Dev. 1996 Sep;59(1):73-87 |
1* | J:219340 Molyneaux BJ, Goff LA, Brettler AC, Chen HH, Brown JR, Hrvatin S, Rinn JL, Arlotta P, DeCoN: genome-wide analysis of in vivo transcriptional dynamics during pyramidal neuron fate selection in neocortex. Neuron. 2015 Jan 21;85(2):275-88 |
1 | J:306633 Tsyporin J, Tastad D, Ma X, Nehme A, Finn T, Huebner L, Liu G, Gallardo D, Makhamreh A, Roberts JM, Katzman S, Sestan N, McConnell SK, Yang Z, Qiu S, Chen B, Transcriptional repression by FEZF2 restricts alternative identities of cortical projection neurons. Cell Rep. 2021 Jun;35 |
1* | J:47495 Yao J, Liu Y, Husain J, Lo R, Palaparti A, Henderson J, Stifani S, Combinatorial expression patterns of individual TLE proteins during cell determination and differentiation suggest non-redundant functions for mammalian homologs of Drosophila Groucho. Dev Growth Differ. 1998 Apr;40(2):133-46 |
Tle5 TLE family member 5, transcriptional modulator (Synonyms: Aes, AES, Grg, Grg5) | |
Results | Reference |
1 | J:60107 Allen T, Lobe CG, A comparison of Notch, Hes and Grg expression during murine embryonic and post-natal development. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):687-708 |
1 | J:86317 Brinkmeier ML, Potok MA, Cha KB, Gridley T, Stifani S, Meeldijk J, Clevers H, Camper SA, TCF and Groucho-related genes influence pituitary growth and development. Mol Endocrinol. 2003 Nov;17(11):2152-61 |
1* | J:13403 Mallo M, Franco del Amo F, Gridley T, Cloning and developmental expression of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex. Mech Dev. 1993 Jul;42(1-2):67-76 |
Tln1 talin 1 | |
Results | Reference |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Tlr2 toll-like receptor 2 (Synonyms: Ly105) | |
Results | Reference |
1 | J:135431 Salminen A, Paananen R, Vuolteenaho R, Metsola J, Ojaniemi M, Autio-Harmainen H, Hallman M, Maternal endotoxin-induced preterm birth in mice: fetal responses in toll-like receptors, collectins, and cytokines. Pediatr Res. 2008 Mar;63(3):280-6 |
Tlr3 toll-like receptor 3 | |
Results | Reference |
1* | J:143513 Lathia JD, Okun E, Tang SC, Griffioen K, Cheng A, Mughal MR, Laryea G, Selvaraj PK, ffrench-Constant C, Magnus T, Arumugam TV, Mattson MP, Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation. J Neurosci. 2008 Dec 17;28(51):13978-84 |
Tlr4 toll-like receptor 4 (Synonyms: lipopolysaccharide response, Lps, Rasl2-8) | |
Results | Reference |
1 | J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47 |
1 | J:135431 Salminen A, Paananen R, Vuolteenaho R, Metsola J, Ojaniemi M, Autio-Harmainen H, Hallman M, Maternal endotoxin-induced preterm birth in mice: fetal responses in toll-like receptors, collectins, and cytokines. Pediatr Res. 2008 Mar;63(3):280-6 |
Tlx1 T cell leukemia, homeobox 1 (Synonyms: Hox-11, Hox11) | |
Results | Reference |
1* | J:107696 Kanzler B, Dear TN, Hox11 acts cell autonomously in spleen development and its absence results in altered cell fate of mesenchymal spleen precursors. Dev Biol. 2001 Jun 1;234(1):231-43 |
1 | J:258875 Mona B, Uruena A, Kollipara RK, Ma Z, Borromeo MD, Chang JC, Johnson JE, Repression by PRDM13 is critical for generating precision in neuronal identity. Elife. 2017 Aug 29;6:e25787 |
1* | J:16396 Raju K, Tang S, Dube ID, Kamel-Reid S, Bryce DM, Breitman ML, Characterization and developmental expression of Tlx-1, the murine homolog of HOX11. Mech Dev. 1993 Nov;44(1):51-64 |
1* | J:17695 Roberts CW, Shutter JR, Korsmeyer SJ, Hox11 controls the genesis of the spleen. Nature. 1994 Apr 21;368(6473):747-9 |
1* | J:30628 Yamamoto H, Hatano M, Iitsuka Y, Mahyar NS, Yamamoto M, Tokuhisa T, Two forms of Hox11 a T cell leukemia oncogene, are expressed in fetal spleen but not in primary lymphocytes. Mol Immunol. 1995 Nov;32(16):1177-82 |
Tlx3 T cell leukemia, homeobox 3 (Synonyms: Hox11l2, Rnx, Tlx1l2) | |
Results | Reference |
1 | J:104420 Glasgow SM, Henke RM, Macdonald RJ, Wright CV, Johnson JE, Ptf1a determines GABAergic over glutamatergic neuronal cell fate in the spinal cord dorsal horn. Development. 2005 Dec;132(24):5461-9 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1 | J:130251 Hori K, Cholewa-Waclaw J, Nakada Y, Glasgow SM, Masui T, Henke RM, Wildner H, Martarelli B, Beres TM, Epstein JA, Magnuson MA, Macdonald RJ, Birchmeier C, Johnson JE, A nonclassical bHLH Rbpj transcription factor complex is required for specification of GABAergic neurons independent of Notch signaling. Genes Dev. 2008 Jan 15;22(2):166-78 |
1 | J:199638 Huang T, Hu J, Wang B, Nie Y, Geng J, Cheng L, Tlx3 controls cholinergic transmitter and Peptide phenotypes in a subset of prenatal sympathetic neurons. J Neurosci. 2013 Jun 26;33(26):10667-75 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:258875 Mona B, Uruena A, Kollipara RK, Ma Z, Borromeo MD, Chang JC, Johnson JE, Repression by PRDM13 is critical for generating precision in neuronal identity. Elife. 2017 Aug 29;6:e25787 |
1 | J:76655 Qian Y, Shirasawa S, Chen CL, Cheng L, Ma Q, Proper development of relay somatic sensory neurons and D2/D4 interneurons requires homeobox genes Rnx/Tlx-3 and Tlx-1. Genes Dev. 2002 May 15;16(10):1220-33 |
1* | J:160590 Rebelo S, Reguenga C, Lopes C, Lima D, Prrxl1 is required for the generation of a subset of nociceptive glutamatergic superficial spinal dorsal horn neurons. Dev Dyn. 2010 Jun;239(6):1684-94 |
1 | J:124186 Rebelo S, Reguenga C, Osorio L, Pereira C, Lopes C, Lima D, DRG11 immunohistochemical expression during embryonic development in the mouse. Dev Dyn. 2007 Sep;236(9):2653-60 |
1 | J:165741 Rojas A, Schachterle W, Xu SM, Martin F, Black BL, Direct transcriptional regulation of Gata4 during early endoderm specification is controlled by FoxA2 binding to an intronic enhancer. Dev Biol. 2010 Oct 15;346(2):346-55 |
1 | J:116148 Stolt CC, Schlierf A, Lommes P, Hillgartner S, Werner T, Kosian T, Sock E, Kessaris N, Richardson WD, Lefebvre V, Wegner M, SoxD proteins influence multiple stages of oligodendrocyte development and modulate SoxE protein function. Dev Cell. 2006 Nov;11(5):697-709 |
2 | J:221159 Stubbusch J, Narasimhan P, Hennchen M, Huber K, Unsicker K, Ernsberger U, Rohrer H, Lineage and stage specific requirement for Dicer1 in sympathetic ganglia and adrenal medulla formation and maintenance. Dev Biol. 2015 Apr 15;400(2):210-23 |
1 | J:343072 Vermeiren S, Cabochette P, Dannawi M, Desiderio S, San Jose AS, Achouri Y, Kricha S, Sitte M, Salinas-Riester G, Vanhollebeke B, Brunet JF, Bellefroid EJ, Prdm12 represses the expression of the visceral neuron determinants Phox2a/b in developing somatosensory ganglia. iScience. 2023 Dec 15;26(12):108364 |
1 | J:201733 Xu Y, Lopes C, Wende H, Guo Z, Cheng L, Birchmeier C, Ma Q, Ontogeny of excitatory spinal neurons processing distinct somatic sensory modalities. J Neurosci. 2013 Sep 11;33(37):14738-48 |
Tm4sf1 transmembrane 4 superfamily member 1 (Synonyms: 12A8 target antigen, L6, L6 antigen, M3s1) | |
Results | Reference |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
Tm4sf4 transmembrane 4 superfamily member 4 (Synonyms: il-TMP, MGC:19127) | |
Results | Reference |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
Tm9sf4 transmembrane 9 superfamily member 4 (Synonyms: mKIAA0255) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Tmbim6 transmembrane BAX inhibitor motif containing 6 (Synonyms: Bax inhibitor 1, Tegt) | |
Results | Reference |
1 | J:291194 Aryal YP, Neupane S, Adhikari N, An CH, Ha JH, Kwon TY, Yamamoto H, Jung JK, Park EK, Kim JY, Cho SW, Sohn WJ, Lee Y, Chae HJ, Kim HR, Kim JY, An endoplasmic reticulum stress regulator, Tmbim6, modulates secretory stage of mice molar. J Cell Physiol. 2019 Nov;234(11):20354-20365 |
Tmcc1 transmembrane and coiled coil domains 1 (Synonyms: 3632431M01Rik) | |
Results | Reference |
1* | J:99372 van der Zwaag B, Burbach JP, Scharfe C, Oefner PJ, Brunner HG, Padberg GW, van Bokhoven H, Identifying new candidate genes for hereditary facial paresis on chromosome 3q21-q22 by RNA in situ hybridization in mouse. Genomics. 2005 Jul;86(1):55-67 |
Tmcc3 transmembrane and coiled coil domains 3 (Synonyms: A230066D03Rik, C630016B22Rik, LOC380656) | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Tmco1 transmembrane and coiled-coil domains 1 (Synonyms: 1190006A08Rik, 4930403O06Rik, ESTM39) | |
Results | Reference |
3 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
Tmeff2 transmembrane protein with EGF-like and two follistatin-like domains 2 (Synonyms: 4832418D20Rik, 7630402F16Rik) | |
Results | Reference |
1 | J:274105 Huang H, Teng P, Mei R, Yang A, Zhang Z, Zhao X, Qiu M, Tmeff2 is expressed in differentiating oligodendrocytes but dispensable for their differentiation in vivo. Sci Rep. 2017 Mar 23;7(1):337 |
Tmem40 transmembrane protein 40 (Synonyms: 9030407H20Rik) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Tmem53 transmembrane protein 53 (Synonyms: 1110038M16Rik, 1500001P22Rik, 1700012A05Rik) | |
Results | Reference |
1* | J:306057 Guo L, Iida A, Bhavani GS, Gowrishankar K, Wang Z, Xue JY, Wang J, Miyake N, Matsumoto N, Hasegawa T, Iizuka Y, Matsuda M, Nakashima T, Takechi M, Iseki S, Yambe S, Nishimura G, Koseki H, Shukunami C, Girisha KM, Ikegawa S, Deficiency of TMEM53 causes a previously unknown sclerosing bone disorder by dysregulation of BMP-SMAD signaling. Nat Commun. 2021 Apr 6;12(1):2046 |
Tmem61 transmembrane protein 61 (Synonyms: 4732441L20Rik) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Tmem98 transmembrane protein 98 (Synonyms: 6530411B15Rik, Rwhs) | |
Results | Reference |
1 | J:287119 Cross SH, Mckie L, Hurd TW, Riley S, Wills J, Barnard AR, Young F, MacLaren RE, Jackson IJ, The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification. PLoS Genet. 2020 Apr;16(4):e1008583 |
Tmem100 transmembrane protein 100 (Synonyms: 1810057C19Rik) | |
Results | Reference |
1 | J:186473 Somekawa S, Imagawa K, Hayashi H, Sakabe M, Ioka T, Sato GE, Inada K, Iwamoto T, Mori T, Uemura S, Nakagawa O, Saito Y, Tmem100, an ALK1 receptor signaling-dependent gene essential for arterial endothelium differentiation and vascular morphogenesis. Proc Natl Acad Sci U S A. 2012 Jul 24;109(30):12064-9 |
Tmem116 transmembrane protein 116 (Synonyms: 4930406A18Rik, 4930513P12Rik, C030022K24Rik) | |
Results | Reference |
2* | J:314587 Zhang S, Dai H, Li W, Wang R, Wu H, Shen M, Hu Y, Xie L, Xing Y, TMEM116 is required for lung cancer cell motility and metastasis through PDK1 signaling pathway. Cell Death Dis. 2021 Nov 16;12(12):1086 |
Tmem151a transmembrane protein 151A (Synonyms: LOC381199, Tmem151) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Tmem161a transmembrane protein 161A (Synonyms: MGC:29210) | |
Results | Reference |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
Tmem161b transmembrane protein 161B (Synonyms: 2810446P07Rik) | |
Results | Reference |
1* | J:225478 Oliver PL, Chodroff RA, Gosal A, Edwards B, Cheung AF, Gomez-Rodriguez J, Elliot G, Garrett LJ, Lickiss T, Szele F, Green ED, Molnar Z, Ponting CP, Disruption of Visc-2, a Brain-Expressed Conserved Long Noncoding RNA, Does Not Elicit an Overt Anatomical or Behavioral Phenotype. Cereb Cortex. 2015 Oct;25(10):3572-85 |
Tmem184a transmembrane protein 184a (Synonyms: MGC:30809, MGC:37596, Sdmg1) | |
Results | Reference |
1* | J:142647 Best D, Adams IR, Sdmg1 is a component of secretory granules in mouse secretory exocrine tissues. Dev Dyn. 2008 Dec 18;238(1):223-231 |
1* | J:122361 Svingen T, Beverdam A, Bernard P, McClive P, Harley VR, Sinclair AH, Koopman P, Sex-specific expression of a novel gene Tmem184a during mouse testis differentiation. Reproduction. 2007 May;133(5):983-9 |
Tmem184c transmembrane protein 184C (Synonyms: 8430433H16Rik, MGC:8158, Tmem34) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Tmem204 transmembrane protein 204 (Synonyms: Clp24) | |
Results | Reference |
1* | J:159519 Saharinen P, Helotera H, Miettinen J, Norrmen C, D'Amico G, Jeltsch M, Langenberg T, Vandevelde W, Ny A, Dewerchin M, Carmeliet P, Alitalo K, Claudin-like protein 24 interacts with the VEGFR-2 and VEGFR-3 pathways and regulates lymphatic vessel development. Genes Dev. 2010 May;24(9):875-80 |
Tmem212 transmembrane protein 212 (Synonyms: E030011K20Rik) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Tmem233 transmembrane protein 233 (Synonyms: Gm13843) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Tmie transmembrane inner ear (Synonyms: 5131400L21Rik, Mm.87012) | |
Results | Reference |
1 | J:307596 De Rosa A, Mastrostefano F, Di Maio A, Nuzzo T, Saitoh Y, Katane M, Isidori AM, Caputo V, Marotta P, Falco G, De Stefano ME, Homma H, Usiello A, Errico F, Prenatal expression of D-aspartate oxidase causes early cerebral D-aspartate depletion and influences brain morphology and cognitive functions at adulthood. Amino Acids. 2020 Apr;52(4):597-617 |
1 | J:330450 Ji YR, Tona Y, Wafa T, Christman ME, Tourney ED, Jiang T, Ohta S, Cheng H, Fitzgerald T, Fritzsch B, Jones SM, Cullen KE, Wu DK, Function of bidirectional sensitivity in the otolith organs established by transcription factor Emx2. Nat Commun. 2022 Oct 24;13(1):6330 |
Tmod1 tropomodulin 1 (Synonyms: erythrocyte tropomodulin, E-Tmod) | |
Results | Reference |
1* | J:22993 Ito M, Swanson B, Sussman MA, Kedes L, Lyons G, Cloning of tropomodulin cDNA and localization of gene transcripts during mouse embryogenesis. Dev Biol. 1995 Jan;167(1):317-28 |
Tmpo thymopoietin (Synonyms: 5630400D24Rik, lamina-associated polypeptide 2, LAP2, TP) | |
Results | Reference |
1 | J:264980 Coffinier C, Jung HJ, Nobumori C, Chang S, Tu Y, Barnes RH 2nd, Yoshinaga Y, de Jong PJ, Vergnes L, Reue K, Fong LG, Young SG, Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons. Mol Biol Cell. 2011 Dec;22(23):4683-93 |
1* | J:120114 Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY, A biphasic pattern of gene expression during mouse retina development. BMC Dev Biol. 2006;6:48 |
Tmprss2 transmembrane protease, serine 2 (Synonyms: D16Ertd61e, epitheliasin) | |
Results | Reference |
1* | J:105558 Kim TS, Heinlein C, Hackman RC, Nelson PS, Phenotypic analysis of mice lacking the Tmprss2-encoded protease. Mol Cell Biol. 2006 Feb;26(3):965-75 |
Tmprss6 transmembrane serine protease 6 (Synonyms: 1300008A22Rik, matriptase-2) | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Tmsb4x thymosin, beta 4, X chromosome (Synonyms: Ptmb4, Tb4, Tbeta4) | |
Results | Reference |
1* | J:147939 Dhaese S, Vandepoele K, Waterschoot D, Vanloo B, Vandekerckhove J, Ampe C, Van Troys M, The mouse thymosin beta15 gene family displays unique complexity and encodes a functional thymosin repeat. J Mol Biol. 2009 Apr 10;387(4):809-25 |
1* | J:207642 Shiotsuka M, Wada H, Kiyoshima T, Nagata K, Fujiwara H, Kihara M, Hasegawa K, Someya H, Takahashi I, Sakai H, The expression and function of thymosin beta 10 in tooth germ development. Int J Dev Biol. 2013;57(11-12):873-83 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1 | J:309992 Vasilopoulou E, Kolatsi-Joannou M, Lindenmeyer MT, White KE, Robson MG, Cohen CD, Sebire NJ, Riley PR, Winyard PJ, Long DA, Loss of endogenous thymosin beta4 accelerates glomerular disease. Kidney Int. 2016 Nov;90(5):1056-1070 |
Tmsb10 thymosin beta 10 (Synonyms: Ptmb10, Tb10) | |
Results | Reference |
1* | J:147939 Dhaese S, Vandepoele K, Waterschoot D, Vanloo B, Vandekerckhove J, Ampe C, Van Troys M, The mouse thymosin beta15 gene family displays unique complexity and encodes a functional thymosin repeat. J Mol Biol. 2009 Apr 10;387(4):809-25 |
1* | J:207642 Shiotsuka M, Wada H, Kiyoshima T, Nagata K, Fujiwara H, Kihara M, Hasegawa K, Someya H, Takahashi I, Sakai H, The expression and function of thymosin beta 10 in tooth germ development. Int J Dev Biol. 2013;57(11-12):873-83 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Tmsb15a thymosin beta 15a (Synonyms: 1700129I15Rik, Tb15a, Tmsl8) | |
Results | Reference |
1* | J:147939 Dhaese S, Vandepoele K, Waterschoot D, Vanloo B, Vandekerckhove J, Ampe C, Van Troys M, The mouse thymosin beta15 gene family displays unique complexity and encodes a functional thymosin repeat. J Mol Biol. 2009 Apr 10;387(4):809-25 |
Tmsb15b1 thymosin beta 15b1 (Synonyms: Tm15b) | |
Results | Reference |
1* | J:147939 Dhaese S, Vandepoele K, Waterschoot D, Vanloo B, Vandekerckhove J, Ampe C, Van Troys M, The mouse thymosin beta15 gene family displays unique complexity and encodes a functional thymosin repeat. J Mol Biol. 2009 Apr 10;387(4):809-25 |
Tmsb15b2 thymosin beta 15b2 (Synonyms: Tb15c) | |
Results | Reference |
1* | J:147939 Dhaese S, Vandepoele K, Waterschoot D, Vanloo B, Vandekerckhove J, Ampe C, Van Troys M, The mouse thymosin beta15 gene family displays unique complexity and encodes a functional thymosin repeat. J Mol Biol. 2009 Apr 10;387(4):809-25 |
Tmsb15l thymosin beta 15b like (Synonyms: 4930488E11Rik, Tb15r, Tmsb15b1-Tmsb15b2) | |
Results | Reference |
1* | J:147939 Dhaese S, Vandepoele K, Waterschoot D, Vanloo B, Vandekerckhove J, Ampe C, Van Troys M, The mouse thymosin beta15 gene family displays unique complexity and encodes a functional thymosin repeat. J Mol Biol. 2009 Apr 10;387(4):809-25 |
Tmtc3 transmembrane and tetratricopeptide repeat containing 3 (Synonyms: 9130014E20Rik, B130008E12Rik, mSmile) | |
Results | Reference |
1* | J:178869 Yun EJ, Vu TH, mSmile is Necessary for Bronchial Smooth Muscle and Alveolar Myofibroblast Development. Anat Rec (Hoboken). 2012 Jan;295(1):167-76 |
Tmx3 thioredoxin-related transmembrane protein 3 (Synonyms: 6430411B10Rik, A730024F05Rik, mKIAA1830, Txndc10) | |
Results | Reference |
1* | J:160833 Chao R, Nevin L, Agarwal P, Riemer J, Bai X, Delaney A, Akana M, JimenezLopez N, Bardakjian T, Schneider A, Chassaing N, Schorderet DF, FitzPatrick D, Kwok PY, Ellgaard L, Gould DB, Zhang Y, Malicki J, Baier H, Slavotinek A, A male with unilateral microphthalmia reveals a role for TMX3 in eye development. PLoS One. 2010;5(5):e10565 |
Tnc tenascin C (Synonyms: C130033P17Rik, cytotactin, hexabrachion, Hxb, tenascin-C, TN, TN-C) | |
Results | Reference |
2* | J:105375 Ajioka I, Maeda T, Nakajima K, Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development. Eur J Neurosci. 2006 Jan;23(2):296-308 |
1 | J:226941 Akerberg BN, Sarangam ML, Stankunas K, Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Dev Biol. 2015 Nov 1;407(1):158-72 |
1 | J:245883 Aldeiri B, Roostalu U, Albertini A, Wong J, Morabito A, Cossu G, Transgelin-expressing myofibroblasts orchestrate ventral midline closure through TGFbeta signalling. Development. 2017 Sep 15;144(18):3336-3348 |
1* | J:152889 Aufderheide E, Chiquet-Ehrismann R, Ekblom P, Epithelial-mesenchymal interactions in the developing kidney lead to expression of tenascin in the mesenchyme. J Cell Biol. 1987 Jul;105(1):599-608 |
1 | J:346910 Ayyangar U, Karkhanis A, Tay H, Afandi AFB, Bhattacharjee O, Ks L, Lee SH, Chan J, Raghavan S, Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin. EMBO J. 2024 Apr;43(7):1113-1134 |
1 | J:311884 Berthet E, Chen C, Butcher K, Schneider RA, Alliston T, Amirtharajah M, Smad3 binds Scleraxis and Mohawk and regulates tendon matrix organization. J Orthop Res. 2013 Sep;31(9):1475-83 |
1 | J:335626 Castillo V, Diaz-Astudillo P, Corrales-Orovio R, San Martin S, Egana JT, Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin. Cells. 2023 Apr 22;12(9) |
1 | J:259186 Heng X, Guo Q, Leung AW, Li JY, Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia. Elife. 2017 May 10;6:e23253 |
1 | J:196289 Huegel J, Mundy C, Sgariglia F, Nygren P, Billings PC, Yamaguchi Y, Koyama E, Pacifici M, Perichondrium phenotype and border function are regulated by Ext1 and heparan sulfate in developing long bones: A mechanism likely deranged in Hereditary Multiple Exostoses. Dev Biol. 2013 May 1;377(1):100-12 |
1* | J:55558 Joester A, Faissner A, Evidence for combinatorial variability of tenascin-C isoforms and developmental regulation in the mouse central nervous system. J Biol Chem. 1999 Jun 11;274(24):17144-51 |
2 | J:42541 Kalembey I, Yoshida T, Iriyama K, Sakakura T, Analysis of tenascin mRNA expression in the murine mammary gland from embryogenesis to carcinogenesis: an in situ hybridization study. Int J Dev Biol. 1997 Aug;41(4):569-73 |
2 | J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47 |
1 | J:205567 Li K, Leung AW, Guo Q, Yang W, Li JY, Shp2-Dependent ERK Signaling Is Essential for Induction of Bergmann Glia and Foliation of the Cerebellum. J Neurosci. 2014 Jan 15;34(3):922-31 |
1 | J:333369 Lipp SN, Jacobson KR, Colling HA, Tuttle TG, Miles DT, McCreery KP, Calve S, Mechanical loading is required for initiation of extracellular matrix deposition at the developing murine myotendinous junction. Matrix Biol. 2023 Feb;116:28-48 |
1 | J:218941 Meier F, Giesert F, Delic S, Faus-Kessler T, Matheus F, Simeone A, Holter SM, Kuhn R, Weisenhorn DM, Wurst W, Prakash N, FGF/FGFR2 signaling regulates the generation and correct positioning of Bergmann glia cells in the developing mouse cerebellum. PLoS One. 2014;9(7):e101124 |
4 | J:346596 Mubuchi A, Takechi M, Nishio S, Matsuda T, Itoh Y, Sato C, Kitajima K, Kitagawa H, Miyata S, Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons. Elife. 2024 Mar 21;12 |
1 | J:242339 Ohayon D, Garces A, Joly W, Soukkarieh C, Takagi T, Sabourin JC, Agius E, Darling DS, De Santa Barbara P, Higashi Y, Stolt CC, Hugnot JP, Richardson WD, Carroll P, Pattyn A, Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Cell Rep. 2016 Nov 01;17(6):1473-1481 |
2 | J:162001 Piper M, Barry G, Hawkins J, Mason S, Lindwall C, Little E, Sarkar A, Smith AG, Moldrich RX, Boyle GM, Tole S, Gronostajski RM, Bailey TL, Richards LJ, NFIA controls telencephalic progenitor cell differentiation through repression of the Notch effector Hes1. J Neurosci. 2010 Jul 7;30(27):9127-39 |
1 | J:160038 Piper M, Moldrich RX, Lindwall C, Little E, Barry G, Mason S, Sunn N, Kurniawan ND, Gronostajski RM, Richards LJ, Multiple non-cell-autonomous defects underlie neocortical callosal dysgenesis in Nfib-deficient mice. Neural Dev. 2009;4:43 |
1* | J:320343 Randilini A, Fujikawa K, Shibata S, An in situ hybridization study of decorin and biglycan mRNA in mouse osteoblasts in vivo. Anat Sci Int. 2021 Mar;96(2):265-272 |
1 | J:74132 Sahlberg C, Aukhil I, Thesleff I, Tenascin-C in developing mouse teeth: expression of splice variants and stimulation by TGFbeta and FGF. Eur J Oral Sci. 2001 Apr;109(2):114-24 |
1 | J:87910 Scherberich A, Tucker RP, Samandari E, Brown-Luedi M, Martin D, Chiquet-Ehrismann R, Murine tenascin-W: a novel mammalian tenascin expressed in kidney and at sites of bone and smooth muscle development. J Cell Sci. 2004 Feb 1;117(Pt 4):571-81 |
1* | J:53565 Whitlon DS, Zhang X, Kusakabe M, Tenascin-C in the cochlea of the developing mouse. J Comp Neurol. 1999 Apr 12;406(3):361-74 |
1 | J:176365 Yallowitz AR, Hrycaj SM, Short KM, Smyth IM, Wellik DM, Hox10 genes function in kidney development in the differentiation and integration of the cortical stroma. PLoS One. 2011;6(8):e23410 |
1 | J:36639 Yuasa S, Bergmann glial development in the mouse cerebellum as revealed by tenascin expression. Anat Embryol (Berl). 1996 Sep;194(3):223-34 |
1 | J:74157 Yuasa S, Development of astrocytes in the mouse hippocampus as tracked by tenascin-C gene expression. Arch Histol Cytol. 2001 May;64(2):149-58 |
Tnf tumor necrosis factor (Synonyms: DIF, Tnfa, TNF alpha, TNF-alpha, TNFalpha, Tnfsf1a, tumor necrosis factor-alpha) | |
Results | Reference |
1* | J:17727 Burns TM, Clough JA, Klein RM, Wood GW, Berman NE, Developmental regulation of cytokine expression in the mouse brain. Growth Factors. 1993;9(4):253-8 |
1 | J:21326 Deman J, Humblet C, Martin MT, Boniver J, Defresne MP, Analysis by in situ hybridization of cytokine mRNA expression in the murine developing thymus. Int Immunol. 1994 Oct;6(10):1613-9 |
1* | J:35158 Deman J, Van Meurs M, Claassen E, Humblet C, Boniver J, Defresne MP, In vivo expression of interleukin-1 beta (IL-1 beta), IL-2, IL-4, IL-6, tumour necrosis factor-alpha and interferon-gamma in the fetal murine thymus. Immunology. 1996 Sep;89(1):152-7 |
1 | J:307825 Fisher AL, Sangkhae V, Balusikova K, Palaskas NJ, Ganz T, Nemeth E, Iron-dependent apoptosis causes embryotoxicity in inflamed and obese pregnancy. Nat Commun. 2021 Jun 29;12(1):4026 |
1 | J:137419 Kajino-Sakamoto R, Inagaki M, Lippert E, Akira S, Robine S, Matsumoto K, Jobin C, Ninomiya-Tsuji J, Enterocyte-derived TAK1 signaling prevents epithelium apoptosis and the development of ileitis and colitis. J Immunol. 2008 Jul 15;181(2):1143-52 |
1 | J:170178 Kobayashi K, Umezawa K, Yasui M, Apoptosis in mouse amniotic epithelium is induced by activated macrophages through the TNF receptor type 1/TNF pathway. Biol Reprod. 2011 Feb;84(2):248-54 |
1 | J:239115 Kurbet AS, Hegde S, Bhattacharjee O, Marepally S, Vemula PK, Raghavan S, Sterile Inflammation Enhances ECM Degradation in Integrin beta1 KO Embryonic Skin. Cell Rep. 2016 Sep 20;16(12):3334-47 |
1 | J:68367 Melnick M, Chen H, Zhou YM, Jaskoll T, Interleukin-6 signaling and embryonic mouse submandibular salivary gland morphogenesis. Cells Tissues Organs. 2001;168(4):233-45 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1* | J:44503 Montgomery RA, Dallman MJ, Semi-quantitative polymerase chain reaction analysis of cytokine and cytokine receptor gene expression during thymic ontogeny. Cytokine. 1997 Oct;9(10):717-26 |
1 | J:135431 Salminen A, Paananen R, Vuolteenaho R, Metsola J, Ojaniemi M, Autio-Harmainen H, Hallman M, Maternal endotoxin-induced preterm birth in mice: fetal responses in toll-like receptors, collectins, and cytokines. Pediatr Res. 2008 Mar;63(3):280-6 |
Tnfaip2 tumor necrosis factor, alpha-induced protein 2 (Synonyms: Exoc3l3, M-sec, Tnfip2) | |
Results | Reference |
2* | J:16743 Wolf FW, Sarma V, Seldin M, Drake S, Suchard SJ, Shao H, O'Shea KS, Dixit VM, B94, a primary response gene inducible by tumor necrosis factor-alpha, is expressed in developing hematopoietic tissues and the sperm acrosome. J Biol Chem. 1994 Feb 4;269(5):3633-40 |
Tnfaip3 tumor necrosis factor, alpha-induced protein 3 (Synonyms: A20, Tnfip3, zinc finger protein A20) | |
Results | Reference |
1 | J:43379 Tewari M, Wolf FW, Seldin MF, O'Shea KS, Dixit VM, Turka LA, Lymphoid expression and regulation of A20, an inhibitor of programmed cell death. J Immunol. 1995 Feb 15;154(4):1699-706 |
Tnfrsf1a tumor necrosis factor receptor superfamily, member 1a (Synonyms: CD120a, p55, p55-R, TNF-alpha-R1, TNF-alphaR1, TNFalpha-R1, TNFAR, Tnfr1, TNF-R1, TNF-R55, TNFR60, TNF receptor alpha chain, TNF-R-I, TNFRI, TNFRp55) | |
Results | Reference |
1 | J:170178 Kobayashi K, Umezawa K, Yasui M, Apoptosis in mouse amniotic epithelium is induced by activated macrophages through the TNF receptor type 1/TNF pathway. Biol Reprod. 2011 Feb;84(2):248-54 |
Tnfrsf10b tumor necrosis factor receptor superfamily, member 10b (Synonyms: DR5, KILLER, Killer/Dr5, Ly98, TRAIL-R2, TRAILR2, Trail Receptor, TRICK2A, TRICK2B, TRICKB) | |
Results | Reference |
1 | J:181055 Niu Y, Li Y, Zang J, Huang H, Deng J, Cui Z, Yu D, Deng J, Death receptor 5 and neuroproliferation. Cell Mol Neurobiol. 2012 Mar;32(2):255-65 |
Tnfrsf11a tumor necrosis factor receptor superfamily, member 11a, NFKB activator (Synonyms: Rank, TRANCE-R) | |
Results | Reference |
1 | J:340406 Lai Y, Guo Y, Liao C, Mao C, Liu J, Ren C, Yang W, Luo L, Chen W, Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development. Sci Rep. 2023 Sep 13;13(1):15170 |
Tnfrsf11b tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Synonyms: OCIF, Opg, OPG, osteoclastogenesis inhibitory factor, TR1) | |
Results | Reference |
1 | J:98430 Glass DA 2nd, Bialek P, Ahn JD, Starbuck M, Patel MS, Clevers H, Taketo MM, Long F, McMahon AP, Lang RA, Karsenty G, Canonical wnt signaling in differentiated osteoblasts controls osteoclast differentiation. Dev Cell. 2005 May;8(5):751-64 |
1 | J:237341 Houben A, Kostanova-Poliakova D, Weissenbock M, Graf J, Teufel S, von der Mark K, Hartmann C, beta-catenin activity in late hypertrophic chondrocytes locally orchestrates osteoblastogenesis and osteoclastogenesis. Development. 2016 Oct 15;143(20):3826-3838 |
1 | J:340406 Lai Y, Guo Y, Liao C, Mao C, Liu J, Ren C, Yang W, Luo L, Chen W, Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development. Sci Rep. 2023 Sep 13;13(1):15170 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
Tnfrsf12a tumor necrosis factor receptor superfamily, member 12a (Synonyms: Fn14, TweakR, TWEAK-R) | |
Results | Reference |
2 | J:330441 Ortega MA, Villiger RK, Harrison-Chau M, Lieu S, Tamashiro KK, Lee AJ, Fujimoto BA, Patwardhan GY, Kepler J, Fogelgren B, Exocyst inactivation in urothelial cells disrupts autophagy and activates non-canonical NF-kappaB signaling. Dis Model Mech. 2022 Oct 1;15(10):dmm049785 |
Tnfrsf19 tumor necrosis factor receptor superfamily, member 19 (Synonyms: TAJ, TAJ-ALPHA, TRADE, Troy) | |
Results | Reference |
1* | J:63235 Kojima T, Morikawa Y, Copeland NG, Gilbert DJ, Jenkins NA, Senba E, Kitamura T, TROY, a newly identified member of the tumor necrosis factor receptor superfamily, exhibits a homology with Edar and is expressed in embryonic skin and hair follicles. J Biol Chem. 2000 Jul 7;275(27):20742-7 |
Tnfrsf22 tumor necrosis factor receptor superfamily, member 22 (Synonyms: 2810028K06Rik, C130035G06Rik, mDcTrailr2, SOBa, Tnfrh2) | |
Results | Reference |
1* | J:186763 Esperon Ede L, Cordier G, Engel N, A genomic reservoir for Tnfrsf genes is developmentally regulated and imprinted in the mouse. Epigenetics. 2012 Jun 1;7(6):626-34 |
Tnfrsf23 tumor necrosis factor receptor superfamily, member 23 (Synonyms: mDcTrailr1, mSOB, Tnfrh1) | |
Results | Reference |
1* | J:186763 Esperon Ede L, Cordier G, Engel N, A genomic reservoir for Tnfrsf genes is developmentally regulated and imprinted in the mouse. Epigenetics. 2012 Jun 1;7(6):626-34 |
Tnfrsf26 tumor necrosis factor receptor superfamily, member 26 (Synonyms: Tnfrh3) | |
Results | Reference |
1* | J:186763 Esperon Ede L, Cordier G, Engel N, A genomic reservoir for Tnfrsf genes is developmentally regulated and imprinted in the mouse. Epigenetics. 2012 Jun 1;7(6):626-34 |
Tnfsf11 tumor necrosis factor (ligand) superfamily, member 11 (Synonyms: Ly109l, ODF, OPGL, OPGL, osteoclast differentiation factor, RANKL, Trance) | |
Results | Reference |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
1 | J:159868 Benezech C, White A, Mader E, Serre K, Parnell S, Pfeffer K, Ware CF, Anderson G, Caamano JH, Ontogeny of stromal organizer cells during lymph node development. J Immunol. 2010 Apr 15;184(8):4521-30 |
1* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:150187 Guo X, Mak KK, Taketo MM, Yang Y, The Wnt/beta-catenin pathway interacts differentially with PTHrP signaling to control chondrocyte hypertrophy and final maturation. PLoS One. 2009;4(6):e6067 |
2 | J:340406 Lai Y, Guo Y, Liao C, Mao C, Liu J, Ren C, Yang W, Luo L, Chen W, Osteoclast differentiation and dynamic mRNA expression during mice embryonic palatal bone development. Sci Rep. 2023 Sep 13;13(1):15170 |
1 | J:153980 Matsushita T, Chan YY, Kawanami A, Balmes G, Landreth GE, Murakami S, Extracellular signal-regulated kinase 1 (ERK1) and ERK2 play essential roles in osteoblast differentiation and in supporting osteoclastogenesis. Mol Cell Biol. 2009 Nov;29(21):5843-57 |
1 | J:299239 Qin X, Jiang Q, Nagano K, Moriishi T, Miyazaki T, Komori H, Ito K, Mark KV, Sakane C, Kaneko H, Komori T, Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts. PLoS Genet. 2020 Nov;16(11):e1009169 |
1 | J:150308 Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009 May 1;182(9):5439-45 |
1 | J:87592 Zhou HM, Weskamp G, Chesneau V, Sahin U, Vortkamp A, Horiuchi K, Chiusaroli R, Hahn R, Wilkes D, Fisher P, Baron R, Manova K, Basson CT, Hempstead B, Blobel CP, Essential role for ADAM19 in cardiovascular morphogenesis. Mol Cell Biol. 2004 Jan;24(1):96-104 |
Tnfsf12 tumor necrosis factor (ligand) superfamily, member 12 (Synonyms: APO3L, DR3L, Tweak) | |
Results | Reference |
1 | J:330441 Ortega MA, Villiger RK, Harrison-Chau M, Lieu S, Tamashiro KK, Lee AJ, Fujimoto BA, Patwardhan GY, Kepler J, Fogelgren B, Exocyst inactivation in urothelial cells disrupts autophagy and activates non-canonical NF-kappaB signaling. Dis Model Mech. 2022 Oct 1;15(10):dmm049785 |
Tnip1 TNFAIP3 interacting protein 1 (Synonyms: A20-binding inhibitor of NF-kappa B activation, ABIN1, Nef, VAN) | |
Results | Reference |
1* | J:265712 Dziedzic SA, Su Z, Jean Barrett V, Najafov A, Mookhtiar AK, Amin P, Pan H, Sun L, Zhu H, Ma A, Abbott DW, Yuan J, ABIN-1 regulates RIPK1 activation by linking Met1 ubiquitylation with Lys63 deubiquitylation in TNF-RSC. Nat Cell Biol. 2018 Jan;20(1):58-68 |
Tnk2 tyrosine kinase, non-receptor, 2 (Synonyms: Ack, ACK1, activated p21cdc42Hs kinase, P21cdc42Hs kinase, Pyk1) | |
Results | Reference |
1* | J:112339 La Torre A, Del Rio JA, Soriano E, Urena JM, Expression pattern of ACK1 tyrosine kinase during brain development in the mouse. Gene Expr Patterns. 2006 Oct 2;6(8):886-892 |
Tnmd tenomodulin (Synonyms: 1110017I01Rik, Bricd4, ChM1L, myodulin, TeM, tendin) | |
Results | Reference |
1 | J:311884 Berthet E, Chen C, Butcher K, Schneider RA, Alliston T, Amirtharajah M, Smad3 binds Scleraxis and Mohawk and regulates tendon matrix organization. J Orthop Res. 2013 Sep;31(9):1475-83 |
1 | J:272612 Eyal S, Rubin S, Krief S, Levin L, Zelzer E, Common cellular origin and diverging developmental programs for different sesamoid bones. Development. 2019 Feb 28;146(4):dev167452 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:175747 Liu W, Watson SS, Lan Y, Keene DR, Ovitt CE, Liu H, Schweitzer R, Jiang R, The atypical homeodomain transcription factor Mohawk controls tendon morphogenesis. Mol Cell Biol. 2010 Oct;30(20):4797-807 |
2 | J:83025 Oshima Y, Shukunami C, Honda J, Nishida K, Tashiro F, Miyazaki J, Hiraki Y, Tano Y, Expression and localization of tenomodulin, a transmembrane type chondromodulin-I-related angiogenesis inhibitor, in mouse eyes. Invest Ophthalmol Vis Sci. 2003 May;44(5):1814-23 |
1* | J:265842 Palagano E, Zuccarini G, Prontera P, Borgatti R, Stangoni G, Elisei S, Mantero S, Menale C, Forlino A, Uva P, Oppo M, Vezzoni P, Villa A, Merlo GR, Sobacchi C, Mutations in the Neuroblastoma Amplified Sequence gene in a family affected by Acrofrontofacionasal Dysostosis type 1. Bone. 2018 Sep;114:125-136 |
2 | J:135068 Shukunami C, Takimoto A, Miura S, Nishizaki Y, Hiraki Y, Chondromodulin-I and tenomodulin are differentially expressed in the avascular mesenchyme during mouse and chick development. Cell Tissue Res. 2008 Apr;332(1):111-22 |
1* | J:146224 Staverosky JA, Pryce BA, Watson SS, Schweitzer R, Tubulin polymerization-promoting protein family member 3, Tppp3, is a specific marker of the differentiating tendon sheath and synovial joints. Dev Dyn. 2009 Mar;238(3):685-92 |
1 | J:354236 Wada S, Ideno H, Nakashima K, Komatsu K, Demura N, Tomonari H, Kimura H, Tachibana M, Nifuji A, The histone H3K9 methyltransferase G9a regulates tendon formation during development. Sci Rep. 2024 Sep 5;14(1):20771 |
2* | J:320688 Wada S, Ideno H, Shimada A, Kamiunten T, Nakamura Y, Nakashima K, Kimura H, Shinkai Y, Tachibana M, Nifuji A, H3K9MTase G9a is essential for the differentiation and growth of tenocytes in vitro. Histochem Cell Biol. 2015 Jul;144(1):13-20 |
2 | J:274387 Yoshimoto Y, Takimoto A, Watanabe H, Hiraki Y, Kondoh G, Shukunami C, Scleraxis is required for maturation of tissue domains for proper integration of the musculoskeletal system. Sci Rep. 2017 Mar 22;7:45010 |
Tnn tenascin N (Synonyms: tenascin-W, Tnw) | |
Results | Reference |
1* | J:296375 Holmes G, Gonzalez-Reiche AS, Lu N, Zhou X, Rivera J, Kriti D, Sebra R, Williams AA, Donovan MJ, Potter SS, Pinto D, Zhang B, van Bakel H, Jabs EW, Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis. Cell Rep. 2020 Jul 7;32(1):107871 |
1 | J:267950 Holzman MA, Bergmann JM, Feldman M, Landry-Truchon K, Jeannotte L, Mansfield JH, HOXA5 protein expression and genetic fate mapping show lineage restriction in the developing musculoskeletal system. Int J Dev Biol. 2018;62(11-12):785-796 |
1* | J:121509 Kimura H, Akiyama H, Nakamura T, Crombrugghe B, Tenascin-W inhibits proliferation and differentiation of preosteoblasts during endochondral bone formation. Biochem Biophys Res Commun. 2007 May 18;356(4):935-41 |
1* | J:153103 Mikura A, Okuhara S, Saito M, Ota M, Ueda K, Iseki S, Association of tenascin-W expression with mineralization in mouse calvarial development. Congenit Anom (Kyoto). 2009 Jun;49(2):77-84 |
2 | J:87910 Scherberich A, Tucker RP, Samandari E, Brown-Luedi M, Martin D, Chiquet-Ehrismann R, Murine tenascin-W: a novel mammalian tenascin expressed in kidney and at sites of bone and smooth muscle development. J Cell Sci. 2004 Feb 1;117(Pt 4):571-81 |
Tnnc1 troponin C, cardiac/slow skeletal (Synonyms: cTnC, TnC) | |
Results | Reference |
1* | J:100572 Hagiwara N, Ma B, Ly A, Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H. Dev Dyn. 2005 Oct;234(2):301-11 |
Tnni1 troponin I, skeletal, slow 1 (Synonyms: 2700018B22Rik, ssTnI) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
1 | J:102575 Franco D, Icardo JM, Molecular characterization of the ventricular conduction system in the developing mouse heart: topographical correlation in normal and congenitally malformed hearts. Cardiovasc Res. 2001 Feb 1;49(2):417-29 |
1* | J:100572 Hagiwara N, Ma B, Ly A, Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H. Dev Dyn. 2005 Oct;234(2):301-11 |
1 | J:26132 Zhu L, Lyons GE, Juhasz O, Joya JE, Hardeman EC, Wade R, Developmental regulation of troponin I isoform genes in striated muscles of transgenic mice. Dev Biol. 1995 Jun;169(2):487-503 |
Tnni2 troponin I, skeletal, fast 2 | |
Results | Reference |
1* | J:100572 Hagiwara N, Ma B, Ly A, Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H. Dev Dyn. 2005 Oct;234(2):301-11 |
1* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
1 | J:26132 Zhu L, Lyons GE, Juhasz O, Joya JE, Hardeman EC, Wade R, Developmental regulation of troponin I isoform genes in striated muscles of transgenic mice. Dev Biol. 1995 Jun;169(2):487-503 |
Tnni3 troponin I, cardiac 3 (Synonyms: cardiac troponin I, cTnI, Tn1) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
1 | J:280846 Bezzina CR, Barc J, Mizusawa Y, Remme CA, Gourraud JB, Simonet F, Verkerk AO, Schwartz PJ, Crotti L, Dagradi F, Guicheney P, Fressart V, Leenhardt A, Antzelevitch C, Bartkowiak S, Borggrefe M, Schimpf R, Schulze-Bahr E, Zumhagen S, Behr ER, Bastiaenen R, Tfelt-Hansen J, Olesen MS, Kaab S, Beckmann BM, Weeke P, Watanabe H, Endo N, Minamino T, Horie M, Ohno S, Hasegawa K, Makita N, Nogami A, Shimizu W, Aiba T, Froguel P, Balkau B, Lantieri O, Torchio M, Wiese C, Weber D, Wolswinkel R, Coronel R, Boukens BJ, Bezieau S, Charpentier E, Chatel S, Despres A, Gros F, Kyndt F, Lecointe S, Lindenbaum P, Portero V, Violleau J, Gessler M, Tan HL, Roden DM, Christoffels VM, Le Marec H, Wilde AA, Probst V, Schott JJ, Dina C, Redon R, Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death. Nat Genet. 2013 Sep;45(9):1044-9 |
1 | J:192707 He A, Ma Q, Cao J, von Gise A, Zhou P, Xie H, Zhang B, Hsing M, Christodoulou DC, Cahan P, Daley GQ, Kong SW, Orkin SH, Seidman CE, Seidman JG, Pu WT, Polycomb repressive complex 2 regulates normal development of the mouse heart. Circ Res. 2012 Feb 3;110(3):406-15 |
1* | J:179371 He A, Shen X, Ma Q, Cao J, von Gise A, Zhou P, Wang G, Marquez VE, Orkin SH, Pu WT, PRC2 directly methylates GATA4 and represses its transcriptional activity. Genes Dev. 2012 Jan 1;26(1):37-42 |
1 | J:278877 Li Y, Lv Z, He L, Huang X, Zhang S, Zhao H, Pu W, Li Y, Yu W, Zhang L, Liu X, Liu K, Tang J, Tian X, Wang QD, Lui KO, Zhou B, Genetic Tracing Identifies Early Segregation of the Cardiomyocyte and Nonmyocyte Lineages. Circ Res. 2019 Jul 19;125(3):343-355 |
1 | J:285035 Liu K, Tang M, Jin H, Liu Q, He L, Zhu H, Liu X, Han X, Li Y, Zhang L, Tang J, Pu W, Lv Z, Wang H, Ji H, Zhou B, Triple-cell lineage tracing by a dual reporter on a single allele. J Biol Chem. 2020 Jan 17;295(3):690-700 |
1 | J:326547 Lu P, Wang P, Wu B, Wang Y, Liu Y, Cheng W, Feng X, Yuan X, Atteya MM, Ferro H, Sugi Y, Rydquist G, Esmaily M, Butcher JT, Chang CP, Lenz J, Zheng D, Zhou B, A SOX17-PDGFB signaling axis regulates aortic root development. Nat Commun. 2022 Jul 13;13(1):4065 |
1 | J:141338 Mommersteeg MT, Brown NA, Prall OW, de Gier-de Vries C, Harvey RP, Moorman AF, Christoffels VM, Pitx2c and Nkx2-5 are required for the formation and identity of the pulmonary myocardium. Circ Res. 2007 Oct 26;101(9):902-9 |
1 | J:171035 Norden J, Grieskamp T, Lausch E, van Wijk B, van den Hoff MJ, Englert C, Petry M, Mommersteeg MT, Christoffels VM, Niederreither K, Kispert A, Wt1 and retinoic acid signaling in the subcoelomic mesenchyme control the development of the pleuropericardial membranes and the sinus horns. Circ Res. 2010 Apr 16;106(7):1212-20 |
1 | J:329315 Sheldon C, Farley A, Ma Q, Pu WT, Lin Z, Depletion of VGLL4 Causes Perinatal Lethality without Affecting Myocardial Development. Cells. 2022 Sep 10;11(18) |
1 | J:193198 Wu B, Zhang Z, Lui W, Chen X, Wang Y, Chamberlain AA, Moreno-Rodriguez RA, Markwald RR, O'Rourke BP, Sharp DJ, Zheng D, Lenz J, Baldwin HS, Chang CP, Zhou B, Endocardial cells form the coronary arteries by angiogenesis through myocardial-endocardial VEGF signaling. Cell. 2012 Nov 21;151(5):1083-96 |
1 | J:26132 Zhu L, Lyons GE, Juhasz O, Joya JE, Hardeman EC, Wade R, Developmental regulation of troponin I isoform genes in striated muscles of transgenic mice. Dev Biol. 1995 Jun;169(2):487-503 |
Tnnt1 troponin T1, skeletal, slow (Synonyms: skeletal muscle slow-twitch TnT, ssTnT, sTnT, Tnt) | |
Results | Reference |
1* | J:100572 Hagiwara N, Ma B, Ly A, Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H. Dev Dyn. 2005 Oct;234(2):301-11 |
1 | J:178379 Richard AF, Demignon J, Sakakibara I, Pujol J, Favier M, Strochlic L, Le Grand F, Sgarioto N, Guernec A, Schmitt A, Cagnard N, Huang R, Legay C, Guillet-Deniau I, Maire P, Genesis of muscle fiber-type diversity during mouse embryogenesis relies on Six1 and Six4 gene expression. Dev Biol. 2011 Nov 15;359(2):303-20 |
1* | J:69158 Wang Q, Reiter RS, Huang QQ, Jin JP, Lin JJ, Comparative studies on the expression patterns of three troponin T genes during mouse development. Anat Rec. 2001 May 1;263(1):72-84 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
Tnnt2 troponin T2, cardiac (Synonyms: cardiac TnT, cTnT, Tnt) | |
Results | Reference |
1* | J:325730 Ahuja N, Hiltabidle MS, Rajasekhar H, Voss S, Lu SZ, Barlow HR, Cowdin MA, Daniel E, Vaddaraju V, Anandakumar T, Black E, Cleaver O, Maynard C, Endothelial Cyp26b1 restrains murine heart valve growth during development. Dev Biol. 2022 Jun;486:81-95 |
1 | J:166547 Airik R, Trowe MO, Foik A, Farin HF, Petry M, Schuster-Gossler K, Schweizer M, Scherer G, Kist R, Kispert A, Hydroureternephrosis due to loss of Sox9-regulated smooth muscle cell differentiation of the ureteric mesenchyme. Hum Mol Genet. 2010 Dec 15;19(24):4918-29 |
1* | J:272619 Aydogdu N, Rudat C, Trowe MO, Kaiser M, Ludtke TH, Taketo MM, Christoffels VM, Moon A, Kispert A, TBX2 and TBX3 act downstream of canonical WNT signaling in patterning and differentiation of the mouse ureteric mesenchyme. Development. 2018 Nov 26;145(23):dev171827 |
1 | J:359854 Cano-Carrillo S, Garcia-Padilla C, Aranega AE, Lozano-Velasco E, Franco D, Mef2c- and Nkx2-5-Divergent Transcriptional Regulation of Chick WT1_76127 and Mouse Gm14014 lncRNAs and Their Implication in Epicardial Cell Migration. Int J Mol Sci. 2024 Nov 30;25(23) |
1 | J:217615 Chen HI, Poduri A, Numi H, Kivela R, Saharinen P, McKay AS, Raftrey B, Churko J, Tian X, Zhou B, Wu JC, Alitalo K, Red-Horse K, VEGF-C and aortic cardiomyocytes guide coronary artery stem development. J Clin Invest. 2014 Nov;124(11):4899-914 |
1 | J:131962 Chen JF, Murchison EP, Tang R, Callis TE, Tatsuguchi M, Deng Z, Rojas M, Hammond SM, Schneider MD, Selzman CH, Meissner G, Patterson C, Hannon GJ, Wang DZ, Targeted deletion of Dicer in the heart leads to dilated cardiomyopathy and heart failure. Proc Natl Acad Sci U S A. 2008 Feb 12;105(6):2111-6 |
1 | J:185237 Chen L, Ma Y, Kim EY, Yu W, Schwartz RJ, Qian L, Wang J, Conditional ablation of Ezh2 in murine hearts reveals its essential roles in endocardial cushion formation, cardiomyocyte proliferation and survival. PLoS One. 2012;7(2):e31005 |
1 | J:271384 D'Amato G, Luxan G, del Monte-Nieto G, Martinez-Poveda B, Torroja C, Walter W, Bochter MS, Benedito R, Cole S, Martinez F, Hadjantonakis AK, Uemura A, Jimenez-Borreguero LJ, de la Pompa JL, Sequential Notch activation regulates ventricular chamber development. Nat Cell Biol. 2016 Jan;18(1):7-20 |
1 | J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767 |
1* | J:319356 Dong K, Shen J, He X, Hu G, Wang L, Osman I, Bunting KM, Dixon-Melvin R, Zheng Z, Xin H, Xiang M, Vazdarjanova A, Fulton DJR, Zhou J, CARMN Is an Evolutionarily Conserved Smooth Muscle Cell-Specific LncRNA That Maintains Contractile Phenotype by Binding Myocardin. Circulation. 2021 Dec 7;144(23):1856-1875 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
1* | J:100572 Hagiwara N, Ma B, Ly A, Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H. Dev Dyn. 2005 Oct;234(2):301-11 |
1 | J:335098 Han F, Yang B, Chen Y, Liu L, Cheng X, Huang J, Zhou K, Zhang D, Xu E, Lai M, Lv B, Cheng H, Zhang H, Loss of GLTSCR1 causes congenital heart defects by regulating NPPA transcription. Angiogenesis. 2023 May;26(2):217-232 |
1 | J:342844 Harvey AB, Wolters RA, Deepe RN, Tarolli HG, Drummond JR, Trouten A, Zandi A, Barth JL, Mukherjee R, Romeo MJ, Vaena SG, Tao G, Muise-Helmericks R, Ramos PS, Norris RA, Wessels A, Epicardial deletion of Sox9 leads to myxomatous valve degeneration and identifies Cd109 as a novel gene associated with valve development. J Mol Cell Cardiol. 2023 Nov 5;186:16-30 |
1 | J:183083 Katz TC, Singh MK, Degenhardt K, Rivera-Feliciano J, Johnson RL, Epstein JA, Tabin CJ, Distinct compartments of the proepicardial organ give rise to coronary vascular endothelial cells. Dev Cell. 2012 Mar 13;22(3):639-50 |
1 | J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522 |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
1 | J:284141 Li D, Angermeier A, Wang J, Planar cell polarity signaling regulates polarized second heart field morphogenesis to promote both arterial and venous pole septation. Development. 2019 Oct 9;146(20):dev181719 |
1* | J:350467 Li Y, Ma K, Dong Z, Gao S, Zhang J, Huang S, Yang J, Fang G, Li Y, Li X, Welch C, Griffin EL, Ramaswamy P, Valivullah Z, Liu X, Dong J, Wang DW, Du J, Chung WK, Li Y, Frameshift variants in C10orf71 cause dilated cardiomyopathy in human, mouse, and organoid models. J Clin Invest. 2024 Jun 17;134(12) |
1 | J:344312 Liu H, Zhou R, Li S, Dong J, Fang Y, Luo Y, Su H, Lai B, Liang L, Zhang D, Zhang Y, Shyy JY, Zhou B, Yuan Z, Wang Y, Epigenetic repression of Cend1 by lysine-specific demethylase 1 is essential for murine heart development. iScience. 2024 Jan 19;27(1):108722 |
1 | J:243772 Mamo TM, Wittern AB, Kleppa MJ, Bohnenpoll T, Weiss AC, Kispert A, BMP4 uses several different effector pathways to regulate proliferation and differentiation in the epithelial and mesenchymal tissue compartments of the developing mouse ureter. Hum Mol Genet. 2017 Sep 15;26(18):3553-3563 |
1 | J:326253 Ni L, Lin B, Hu L, Zhang R, Fu F, Shen M, Yang J, Shi D, Pyruvate Kinase M2 Protects Heart from Pressure Overload-Induced Heart Failure by Phosphorylating RAC1. J Am Heart Assoc. 2022 Jun 7;11(11):e024854 |
1 | J:199136 Rog-Zielinska EA, Thomson A, Kenyon CJ, Brownstein DG, Moran CM, Szumska D, Michailidou Z, Richardson J, Owen E, Watt A, Morrison H, Forrester LM, Bhattacharya S, Holmes MC, Chapman KE, Glucocorticoid receptor is required for foetal heart maturation. Hum Mol Genet. 2013 Aug 15;22(16):3269-82 |
1 | J:338889 Siguero-Alvarez M, Salguero-Jimenez A, Grego-Bessa J, de la Barrera J, MacGrogan D, Prados B, Sanchez-Saez F, Pineiro-Sabaris R, Felipe-Medina N, Torroja C, Gomez MJ, Sabater-Molina M, Escriba R, Richaud-Patin I, Iglesias-Garcia O, Sbroggio M, Callejas S, O'Regan DP, McGurk KA, Dopazo A, Giovinazzo G, Ibanez B, Monserrat L, Perez-Pomares JM, Sanchez-Cabo F, Pendas AM, Raya A, Gimeno-Blanes JR, de la Pompa JL, A Human Hereditary Cardiomyopathy Shares a Genetic Substrate With Bicuspid Aortic Valve. Circulation. 2023 Jan 3;147(1):47-65 |
1* | J:244087 Stopp S, Grundl M, Fackler M, Malkmus J, Leone M, Naumann R, Frantz S, Wolf E, von Eyss B, Engel FB, Gaubatz S, Deletion of Gas2l3 in mice leads to specific defects in cardiomyocyte cytokinesis during development. Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):8029-8034 |
1 | J:311811 Trowe MO, Airik R, Weiss AC, Farin HF, Foik AB, Bettenhausen E, Schuster-Gossler K, Taketo MM, Kispert A, Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter. Development. 2012 Sep;139(17):3099-108 |
2* | J:69158 Wang Q, Reiter RS, Huang QQ, Jin JP, Lin JJ, Comparative studies on the expression patterns of three troponin T genes during mouse development. Anat Rec. 2001 May 1;263(1):72-84 |
1 | J:214811 Weiss AC, Airik R, Bohnenpoll T, Greulich F, Foik A, Trowe MO, Rudat C, Costantini F, Adams RH, Kispert A, Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme. Development. 2014 Sep;141(17):3420-30 |
1* | J:279388 Weiss AC, Bohnenpoll T, Kurz J, Blank P, Airik R, Ludtke TH, Kleppa MJ, Deuper L, Kaiser M, Mamo TM, Costa R, von Hahn T, Trowe MO, Kispert A, Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme. J Pathol. 2019 Aug;248(4):452-463 |
2 | J:253740 Yan J, Zhang L, Sultana N, Oh JG, Wu B, Hajjar RJ, Zhou B, Cai CL, A series of robust genetic indicators for definitive identification of cardiomyocytes. J Mol Cell Cardiol. 2016 Aug;97:278-85 |
1 | J:261328 Zou J, Ma W, Li J, Littlejohn R, Zhou H, Kim IM, Fulton DJR, Chen W, Weintraub NL, Zhou J, Su H, Neddylation mediates ventricular chamber maturation through repression of Hippo signaling. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4101-E4110 |
Tnnt3 troponin T3, skeletal, fast (Synonyms: fTnT, skeletal muscle fast-twitch TnT) | |
Results | Reference |
1 | J:283675 Comai G, Heude E, Mella S, Paisant S, Pala F, Gallardo M, Langa F, Kardon G, Gopalakrishnan S, Tajbakhsh S, A distinct cardiopharyngeal mesoderm genetic hierarchy establishes antero-posterior patterning of esophagus striated muscle. Elife. 2019 Sep 19;8:e47460 |
1* | J:100572 Hagiwara N, Ma B, Ly A, Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H. Dev Dyn. 2005 Oct;234(2):301-11 |
1* | J:69158 Wang Q, Reiter RS, Huang QQ, Jin JP, Lin JJ, Comparative studies on the expression patterns of three troponin T genes during mouse development. Anat Rec. 2001 May 1;263(1):72-84 |
Tnr tenascin R (Synonyms: J1-tenascin, janusin, restrictin, TN-R) | |
Results | Reference |
1* | J:33496 Akhurst RJ, Lehnert SA, Faissner A, Duffie E, TGF beta in murine morphogenetic processes: the early embryo and cardiogenesis. Development. 1990 Apr;108(4):645-56 |
Tnrc6a trinucleotide repeat containing 6a (Synonyms: 2010321I05Rik, 3110054G10Rik, CAGH26, D130023A07Rik, MGC:11932, Tnrc6) | |
Results | Reference |
1* | J:160269 Michon F, Tummers M, Kyyronen M, Frilander MJ, Thesleff I, Tooth morphogenesis and ameloblast differentiation are regulated by micro-RNAs. Dev Biol. 2010 Apr 15;340(2):355-68 |
Tob1 transducer of ErbB-2.1 (Synonyms: Tob, Trob) | |
Results | Reference |
1* | J:346062 Perez RC, Yang X, Familari M, Martinez G, Lovicu FJ, Hime GR, de Iongh RU, TOB1 and TOB2 mark distinct RNA processing granules in differentiating lens fiber cells. J Mol Histol. 2024 Feb;55(1):121-138 |
Tob2 transducer of ERBB2, 2 (Synonyms: 2900090N22Rik, 4930545K18Rik, mKIAA1663) | |
Results | Reference |
1* | J:346062 Perez RC, Yang X, Familari M, Martinez G, Lovicu FJ, Hime GR, de Iongh RU, TOB1 and TOB2 mark distinct RNA processing granules in differentiating lens fiber cells. J Mol Histol. 2024 Feb;55(1):121-138 |
Tom1l1 target of myb1-like 1 (chicken) (Synonyms: 2310045L10Rik, Srcasm) | |
Results | Reference |
1* | J:237193 Chaboub LS, Manalo JM, Lee HK, Glasgow SM, Chen F, Kawasaki Y, Akiyama T, Kuo CT, Creighton CJ, Mohila CA, Deneen B, Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury. J Neurosci. 2016 Nov 23;36(47):11904-11917 |
Tomm20 translocase of outer mitochondrial membrane 20 (Synonyms: 1810060K07Rik, MGC:6333, mKIAA0016, TOM20) | |
Results | Reference |
1 | J:235665 He S, Limi S, McGreal RS, Xie Q, Brennan LA, Kantorow WL, Kokavec J, Majumdar R, Hou H Jr, Edelmann W, Liu W, Ashery-Padan R, Zavadil J, Kantorow M, Skoultchi AI, Stopka T, Cvekl A, Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation. Development. 2016 Jun 1;143(11):1937-47 |
1 | J:224310 Ishihara T, Ban-Ishihara R, Maeda M, Matsunaga Y, Ichimura A, Kyogoku S, Aoki H, Katada S, Nakada K, Nomura M, Mizushima N, Mihara K, Ishihara N, Dynamics of mitochondrial DNA nucleoids regulated by mitochondrial fission is essential for maintenance of homogeneously active mitochondria during neonatal heart development. Mol Cell Biol. 2015 Jan;35(1):211-23 |
2 | J:240472 Kumar N, Srivillibhuthur M, Joshi S, Walton KD, Zhou A, Faller WJ, Perekatt AO, Sansom OJ, Gumucio DL, Xing J, Bonder EM, Gao N, White E, Verzi MP, A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis. Development. 2016 Oct 15;143(20):3711-3722 |
2* | J:277128 Shiromoto Y, Kuramochi-Miyagawa S, Nagamori I, Chuma S, Arakawa T, Nishimura T, Hasuwa H, Tachibana T, Ikawa M, Nakano T, GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice. Biol Reprod. 2019 Jul 1;101(1):248-256 |
Top2a topoisomerase (DNA) II alpha (Synonyms: DNA Topoisomerase II alpha, Top-2) | |
Results | Reference |
2 | J:290729 Grundl M, Walz S, Hauf L, Schwab M, Werner KM, Spahr S, Schulte C, Maric HM, Ade CP, Gaubatz S, Interaction of YAP with the Myb-MuvB (MMB) complex defines a transcriptional program to promote the proliferation of cardiomyocytes. PLoS Genet. 2020 May;16(5):e1008818 |
1 | J:316922 Holmes G, Gonzalez-Reiche AS, Saturne M, Motch Perrine SM, Zhou X, Borges AC, Shewale B, Richtsmeier JT, Zhang B, van Bakel H, Jabs EW, Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nat Commun. 2021 Dec 8;12(1):7132 |
1 | J:328936 Qin S, Yuan Y, Huang X, Tan Z, Hu X, Liu H, Pu Y, Ding YQ, Su Z, He C, Topoisomerase IIA in adult NSCs regulates SVZ neurogenesis by transcriptional activation of Usp37. Nucleic Acids Res. 2022 Aug 27; |
1 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
Top2b topoisomerase (DNA) II beta (Synonyms: D230016L12Rik, Top-2) | |
Results | Reference |
1 | J:94879 Lyu YL, Wang JC, Aberrant lamination in the cerebral cortex of mouse embryos lacking DNA topoisomerase IIbeta. Proc Natl Acad Sci U S A. 2003 Jun 10;100(12):7123-8 |
Topaz1 testis and ovary specific PAZ domain containing 1 (Synonyms: Gm9524) | |
Results | Reference |
1* | J:181001 Baillet A, Le Bouffant R, Volff JN, Luangpraseuth A, Poumerol E, Thepot D, Pailhoux E, Livera G, Cotinot C, Mandon-Pepin B, TOPAZ1, a novel germ cell-specific expressed gene conserved during evolution across vertebrates. PLoS One. 2011;6(11):e26950 |
Tox thymocyte selection-associated high mobility group box (Synonyms: 1700007F02Rik) | |
Results | Reference |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
Tox2 TOX high mobility group box family member 2 (Synonyms: LOC269389, RxHMG1) | |
Results | Reference |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
Tpbg trophoblast glycoprotein (Synonyms: 5T4, 5T4 oncofetal antigen) | |
Results | Reference |
1* | J:99569 Barrow KM, Ward CM, Rutter J, Ali S, Stern PL, Embryonic expression of murine 5T4 oncofoetal antigen is associated with morphogenetic events at implantation and in developing epithelia. Dev Dyn. 2005 Aug;233(4):1535-45 |
Tpbpa trophoblast specific protein alpha (Synonyms: 4311, clone 4311, Tb-1, Tb1, Tpbp) | |
Results | Reference |
1 | J:231798 Chen CY, Chan CH, Chen CM, Tsai YS, Tsai TY, Wu Lee YH, You LR, Targeted inactivation of murine Ddx3x: essential roles of Ddx3x in placentation and embryogenesis. Hum Mol Genet. 2016 July 15;25(14):2905-2922 |
1 | J:241566 Chi L, Ahmed A, Roy AR, Vuong S, Cahill LS, Caporiccio L, Sled JG, Caniggia I, Wilson MD, Delgado-Olguin P, G9a controls placental vascular maturation by activating the Notch Pathway. Development. 2017 Jun 01;144(11):1976-1987 |
1 | J:190411 Dong Y, Zhang L, Zhang S, Bai Y, Chen H, Sun X, Yong W, Li W, Colvin SC, Rhodes SJ, Shou W, Zhang ZY, Phosphatase of regenerating liver 2 (PRL2) is essential for placental development by down-regulating PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) and activating Akt protein. J Biol Chem. 2012 Sep 14;287(38):32172-9 |
1 | J:180242 Dupressoir A, Vernochet C, Harper F, Guegan J, Dessen P, Pierron G, Heidmann T, A pair of co-opted retroviral envelope syncytin genes is required for formation of the two-layered murine placental syncytiotrophoblast. Proc Natl Acad Sci U S A. 2011 Nov 15;108(46):E1164-73 |
1 | J:249801 Duval C, Dilworth MR, Tunster SJ, Kimber SJ, Glazier JD, PTHrP is essential for normal morphogenetic and functional development of the murine placenta. Dev Biol. 2017 Oct 15;430(2):325-336 |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
1 | J:123073 Kruger I, Vollmer M, Simmons DG, Elsasser HP, Philipsen S, Suske G, Sp1/Sp3 compound heterozygous mice are not viable: Impaired erythropoiesis and severe placental defects. Dev Dyn. 2007 Aug;236(8):2235-44 |
1* | J:36835 Monkley SJ, Delaney SJ, Pennisi DJ, Christiansen JH, Wainwright BJ, Targeted disruption of the Wnt2 gene results in placentation defects. Development. 1996 Nov;122(11):3343-53 |
1 | J:107381 Nadra K, Anghel SI, Joye E, Tan NS, Basu-Modak S, Trono D, Wahli W, Desvergne B, Differentiation of trophoblast giant cells and their metabolic functions are dependent on peroxisome proliferator-activated receptor beta/delta. Mol Cell Biol. 2006 Apr;26(8):3266-81 |
1 | J:50463 Pitman JL, Lin TP, Kleeman JE, Erickson GF, MacLeod CL, Normal reproductive and macrophage function in Pem homeobox gene-deficient mice. Dev Biol. 1998 Oct 15;202(2):196-214 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
2 | J:180846 Saito K, Ogawa A, Toyofuku K, Hosoi Y, Soma M, Iha M, Kasuga K, Kojima I, Kobayashi M, Relationships between homeoprotein EGAM1C and the expression of the placental prolactin gene family in mouse placentae and trophoblast stem cells. Reproduction. 2011 Feb;141(2):259-68 |
1 | J:240089 Sharma N, Kubaczka C, Kaiser S, Nettersheim D, Mughal SS, Riesenberg S, Holzel M, Winterhager E, Schorle H, Tpbpa-Cre-mediated deletion of TFAP2C leads to deregulation of Cdkn1a, Akt1 and the ERK pathway, causing placental growth arrest. Development. 2016 Mar 01;143(5):787-98 |
1 | J:51692 Teesalu T, Grassi F, Guttinger M, Expression pattern of the epithelial v-like antigen (Eva) transcript suggests a possible role in placental morphogenesis. Dev Genet. 1998;23(4):317-23 |
1* | J:53323 Teesalu T, Masson R, Basset P, Blasi F, Talarico D, Expression of matrix metalloproteinases during murine chorioallantoic placenta maturation. Dev Dyn. 1999 Mar;214(3):248-58 |
2 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
Tpbpb trophoblast specific protein beta (Synonyms: 1600012N09Rik) | |
Results | Reference |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
Tph1 tryptophan hydroxylase 1 | |
Results | Reference |
1 | J:319016 Yan R, Huang T, Xie Z, Xia G, Qian H, Zhao X, Cheng L, Lmx1b controls peptide phenotypes in serotonergic and dopaminergic neurons. Acta Biochim Biophys Sin (Shanghai). 2013 May;45(5):345-52 |
Tph2 tryptophan hydroxylase 2 | |
Results | Reference |
1 | J:237535 Haugas M, Tikker L, Achim K, Salminen M, Partanen J, Gata2 and Gata3 regulate the differentiation of serotonergic and glutamatergic neuron subtypes of the dorsal raphe. Development. 2016 Dec 01;143(23):4495-4508 |
Tpm1 tropomyosin 1, alpha (Synonyms: alpha-TM, TM2, Tm3, Tpm-1) | |
Results | Reference |
1* | J:163968 Liu X, Ramjiganesh T, Chen YH, Chung SW, Hall SR, Schissel SL, Padera RF Jr, Liao R, Ackerman KG, Kajstura J, Leri A, Anversa P, Yet SF, Layne MD, Perrella MA, Disruption of striated preferentially expressed gene locus leads to dilated cardiomyopathy in mice. Circulation. 2009 Jan 20;119(2):261-8 |
1 | J:320916 Teekakirikul P, Zhu W, Xu X, Young CB, Tan T, Smith AM, Wang C, Peterson KA, Gabriel GC, Ho S, Sheng Y, Moreau de Bellaing A, Sonnenberg DA, Lin J, Fotiou E, Tenin G, Wang MX, Wu YL, Feinstein T, Devine W, Gou H, Bais AS, Glennon BJ, Zahid M, wong TC, Ahmad F, Rynkiewiz MJ, Lehman WJ, Keavney B, Alastaqlo TP, Freckmann ML, Orwig K, Murray S, Ware SM, Zhao H, Feingold B, Lo CW, Genetic resiliency associated with dominant lethal TPM1 mutation causing atrial septal defect with high heritability. Cell Rep Med. 2022;3 |
Tpm2 tropomyosin 2, beta (Synonyms: Tpm-2, Trop-2) | |
Results | Reference |
1* | J:321979 Kurz J, Weiss AC, Thiesler H, Qasrawi F, Deuper L, Kaur J, Rudat C, Ludtke TH, Wojahn I, Hildebrandt H, Trowe MO, Kispert A, Notch signaling is a novel regulator of visceral smooth muscle cell differentiation in the murine ureter. Development. 2022 Feb 15;149(4):dev199735 |
2 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Tpm3 tropomyosin 3, gamma (Synonyms: gamma-TM, hTM30nm, hTMnm, skalphaTM.2, Tm5NM, Tpm-5, Tpm5, Trop-5) | |
Results | Reference |
1 | J:200894 Fath T, Agnes Chan YK, Vrhovski B, Clarke H, Curthoys N, Hook J, Lemckert F, Schevzov G, Tam P, Watson CM, Khoo PL, Gunning P, New aspects of tropomyosin-regulated neuritogenesis revealed by the deletion of Tm5NM1 and 2. Eur J Cell Biol. 2010 Jul;89(7):489-98 |
Tpm4 tropomyosin 4 (Synonyms: 2610528G24Rik) | |
Results | Reference |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Tppp3 tubulin polymerization-promoting protein family member 3 (Synonyms: 2700055K07Rik) | |
Results | Reference |
1 | J:272612 Eyal S, Rubin S, Krief S, Levin L, Zelzer E, Common cellular origin and diverging developmental programs for different sesamoid bones. Development. 2019 Feb 28;146(4):dev167452 |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
1* | J:146224 Staverosky JA, Pryce BA, Watson SS, Schweitzer R, Tubulin polymerization-promoting protein family member 3, Tppp3, is a specific marker of the differentiating tendon sheath and synovial joints. Dev Dyn. 2009 Mar;238(3):685-92 |
Tpsab1 tryptase alpha/beta 1 (Synonyms: Mcp-7, Mcpt7, MMCP-7) | |
Results | Reference |
2* | J:113235 Abraham D, Oster H, Huber M, Leitges M, The expression pattern of three mast cell specific proteases during mouse development. Mol Immunol. 2007 Feb;44(5):732-40 |
Tpsb2 tryptase beta 2 (Synonyms: Mcp-6, Mcp6, Mcpt6, MMCP-6) | |
Results | Reference |
2* | J:113235 Abraham D, Oster H, Huber M, Leitges M, The expression pattern of three mast cell specific proteases during mouse development. Mol Immunol. 2007 Feb;44(5):732-40 |
Tpt1 tumor protein, translationally-controlled 1 (Synonyms: fortilin, TCTP, Trt) | |
Results | Reference |
3 | J:301138 Chen SH, Lu CH, Tsai MJ, TCTP is Essential for Cell Proliferation and Survival during CNS Development. Cells. 2020 Jan 6;9(1):133 |
1 | J:148696 Koide Y, Kiyota T, Tonganunt M, Pinkaew D, Liu Z, Kato Y, Hutadilok-Towatana N, Phongdara A, Fujise K, Embryonic lethality of fortilin-null mutant mice by BMP-pathway overactivation. Biochim Biophys Acta. 2009 May;1790(5):326-38 |
1 | J:208719 Tsai MJ, Yang-Yen HF, Chiang MK, Wang MJ, Wu SS, Chen SH, TCTP is essential for beta-cell proliferation and mass expansion during development and beta-cell adaptation in response to insulin resistance. Endocrinology. 2014 Feb;155(2):392-404 |
Tra2a transformer 2 alpha (Synonyms: 1500010G04Rik, G430041M01Rik, mAWMS1) | |
Results | Reference |
1 | J:179807 Grellscheid S, Dalgliesh C, Storbeck M, Best A, Liu Y, Jakubik M, Mende Y, Ehrmann I, Curk T, Rossbach K, Bourgeois CF, Stevenin J, Grellscheid D, Jackson MS, Wirth B, Elliott DJ, Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2beta in development. PLoS Genet. 2011 Dec;7(12):e1002390 |
1 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Tra2b transformer 2 beta (Synonyms: 5730405G21Rik, Sfrs10, Silg41, TRA2beta) | |
Results | Reference |
1* | J:274718 Diao Y, Cui L, Chen Y, Burbridge TJ, Han W, Wirth B, Sestan N, Crair MC, Zhang J, Reciprocal Connections Between Cortex and Thalamus Contribute to Retinal Axon Targeting to Dorsal Lateral Geniculate Nucleus. Cereb Cortex. 2018 Apr 1;28(4):1168-1182 |
3 | J:179807 Grellscheid S, Dalgliesh C, Storbeck M, Best A, Liu Y, Jakubik M, Mende Y, Ehrmann I, Curk T, Rossbach K, Bourgeois CF, Stevenin J, Grellscheid D, Jackson MS, Wirth B, Elliott DJ, Identification of evolutionarily conserved exons as regulated targets for the splicing activator tra2beta in development. PLoS Genet. 2011 Dec;7(12):e1002390 |
2 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Tradd TNFRSF1A-associated via death domain (Synonyms: 9130005N23Rik) | |
Results | Reference |
1* | J:60742 Rosenfeld ME, Prichard L, Shiojiri N, Fausto N, Prevention of hepatic apoptosis and embryonic lethality in RelA/TNFR-1 double knockout mice. Am J Pathol. 2000 Mar;156(3):997-1007 |
Traf1 TNF receptor-associated factor 1 (Synonyms: 4732496E14Rik) | |
Results | Reference |
1* | J:46644 Masson R, Regnier CH, Chenard MP, Wendling C, Mattei MG, Tomasetto C, Rio MC, Tumor necrosis factor receptor associated factor 4 (TRAF4) expression pattern during mouse development. Mech Dev. 1998 Feb;71(1-2):187-91 |
1 | J:264370 Sima J, Yan Z, Chen Y, Lehrmann E, Zhang Y, Nagaraja R, Wang W, Wang Z, Schlessinger D, Eda-activated RelB recruits an SWI/SNF (BAF) chromatin-remodeling complex and initiates gene transcription in skin appendage formation. Proc Natl Acad Sci U S A. 2018 Aug 7;115(32):8173-8178 |
Traf2 TNF receptor-associated factor 2 | |
Results | Reference |
1* | J:46644 Masson R, Regnier CH, Chenard MP, Wendling C, Mattei MG, Tomasetto C, Rio MC, Tumor necrosis factor receptor associated factor 4 (TRAF4) expression pattern during mouse development. Mech Dev. 1998 Feb;71(1-2):187-91 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1* | J:60742 Rosenfeld ME, Prichard L, Shiojiri N, Fausto N, Prevention of hepatic apoptosis and embryonic lethality in RelA/TNFR-1 double knockout mice. Am J Pathol. 2000 Mar;156(3):997-1007 |
Traf3 TNF receptor-associated factor 3 (Synonyms: CAP-1, CD40bp, CRAF1, LAP1) | |
Results | Reference |
1* | J:46644 Masson R, Regnier CH, Chenard MP, Wendling C, Mattei MG, Tomasetto C, Rio MC, Tumor necrosis factor receptor associated factor 4 (TRAF4) expression pattern during mouse development. Mech Dev. 1998 Feb;71(1-2):187-91 |
1* | J:34163 Wang X, Bornslaeger EA, Haub O, Tomihara-Newberger C, Lonberg N, Dinulos MB, Disteche CM, Copeland N, Gilbert DJ, Jenkins NA, Lacy E, A candidate gene for the amnionless gastrulation stage mouse mutation encodes a TRAF-related protein. Dev Biol. 1996 Jul 10;177(1):274-90 |
Traf4 TNF receptor associated factor 4 (Synonyms: A530032M13Rik, CART1, msp2) | |
Results | Reference |
2* | J:46644 Masson R, Regnier CH, Chenard MP, Wendling C, Mattei MG, Tomasetto C, Rio MC, Tumor necrosis factor receptor associated factor 4 (TRAF4) expression pattern during mouse development. Mech Dev. 1998 Feb;71(1-2):187-91 |
Traf6 TNF receptor-associated factor 6 (Synonyms: 2310003F17Rik, C630032O20Rik) | |
Results | Reference |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1 | J:77350 Naito A, Yoshida H, Nishioka E, Satoh M, Azuma S, Yamamoto T, Nishikawa S, Inoue J, TRAF6-deficient mice display hypohidrotic ectodermal dysplasia. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8766-71 |
Traip TRAF-interacting protein (Synonyms: Trip) | |
Results | Reference |
2* | J:127324 Park ES, Choi S, Kim JM, Jeong Y, Choe J, Park CS, Choi Y, Rho J, Early embryonic lethality caused by targeted disruption of the TRAF-interacting protein (TRIP) gene. Biochem Biophys Res Commun. 2007 Nov 30;363(4):971-7 |
Trank1 tetratricopeptide repeat and ankyrin repeat containing 1 (Synonyms: A230061D21Rik, C030048J01Rik, Lba1, LOC235639) | |
Results | Reference |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
Trdc T cell receptor delta, constant region (Synonyms: Tcrd-C) | |
Results | Reference |
1 | J:43089 Wilbert OM, Weber-Arden J, Kabelitz D, Arden B, TCR-delta gene rearrangement and selection during fetal thymocyte development. J Immunol. 1997 Oct 1;159(7):3338-46 |
Trdn triadin (Synonyms: 2310045H21Rik, EG432451, triadin 1, triadin-1, triadin 2, triadin-2, triadin 3, triadin-3) | |
Results | Reference |
1* | J:97586 Hong S, Kim TW, Choi I, Woo JM, Oh J, Park WJ, Kim do H, Cho C, Complementary DNA cloning, genomic characterization and expression analysis of a mammalian gene encoding histidine-rich calcium binding protein. Biochim Biophys Acta. 2005 Mar 10;1727(3):188-96 |
Treh trehalase (brush-border membrane glycoprotein) (Synonyms: 2210412M19Rik) | |
Results | Reference |
1 | J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90 |
Trem2 triggering receptor expressed on myeloid cells 2 (Synonyms: Trem2a, Trem2b, Trem2c) | |
Results | Reference |
1* | J:346378 Liang Y, Hu Y, Zhang J, Song H, Zhang X, Chen Y, Peng Y, Sun L, Sun Y, Xue R, Ji S, Li C, Rong Z, Yang B, Xu Y, Dynamic pathological analysis reveals a protective role against skin fibrosis for TREM2-dependent macrophages. Theranostics. 2024;14(5):2232-2245 |
Trex1 three prime repair exonuclease 1 | |
Results | Reference |
1* | J:328989 Patel SD, Anand D, Motohashi H, Katsuoka F, Yamamoto M, Lachke SA, Deficiency of the bZIP transcription factors Mafg and Mafk causes misexpression of genes in distinct pathways and results in lens embryonic developmental defects. Front Cell Dev Biol. 2022;10:981893 |
Trf transferrin (Synonyms: HP, Tfn) | |
Results | Reference |
1 | J:301391 Yu Y, Jiang L, Wang H, Shen Z, Cheng Q, Zhang P, Wang J, Wu Q, Fang X, Duan L, Wang S, Wang K, An P, Shao T, Chung RT, Zheng S, Min J, Wang F, Hepatic transferrin plays a role in systemic iron homeostasis and liver ferroptosis. Blood. 2020 Aug 6;136(6):726-739 |
Trh thyrotropin releasing hormone | |
Results | Reference |
1 | J:326535 Petitpre C, Faure L, Uhl P, Fontanet P, Filova I, Pavlinkova G, Adameyko I, Hadjab S, Lallemend F, Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification. Nat Commun. 2022 Jul 5;13(1):3878 |
1 | J:319016 Yan R, Huang T, Xie Z, Xia G, Qian H, Zhao X, Cheng L, Lmx1b controls peptide phenotypes in serotonergic and dopaminergic neurons. Acta Biochim Biophys Sin (Shanghai). 2013 May;45(5):345-52 |
Triap1 TP53 regulated inhibitor of apoptosis 1 (Synonyms: 1810015M01Rik) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Trib2 tribbles pseudokinase 2 (Synonyms: TRB2) | |
Results | Reference |
1* | J:243411 Rutledge EA, Benazet JD, McMahon AP, Cellular heterogeneity in the ureteric progenitor niche and distinct profiles of branching morphogenesis in organ development. Development. 2017 Sep 01;144(17):3177-3188 |
Trib3 tribbles pseudokinase 3 (Synonyms: Ifld2, Nipk, SKIP3, Trb3) | |
Results | Reference |
1 | J:253948 Magarin M, Pohl T, Lill A, Schulz H, Blaschke F, Heuser A, Thierfelder L, Donath S, Drenckhahn JD, Embryonic cardiomyocytes can orchestrate various cell protective mechanisms to survive mitochondrial stress. J Mol Cell Cardiol. 2016 Aug;97:1-14 |
Trim2 tripartite motif-containing 2 (Synonyms: narf, neural activity-related ring finger protein) | |
Results | Reference |
1 | J:265843 Chowdhury R, Laboissonniere LA, Wester AK, Muller M, Trimarchi JM, The Trim family of genes and the retina: Expression and functional characterization. PLoS One. 2018;13(9):e0202867 |
Trim9 tripartite motif-containing 9 (Synonyms: C030048G07Rik, mKIAA0282) | |
Results | Reference |
1 | J:265843 Chowdhury R, Laboissonniere LA, Wester AK, Muller M, Trimarchi JM, The Trim family of genes and the retina: Expression and functional characterization. PLoS One. 2018;13(9):e0202867 |
1* | J:215804 Winkle CC, McClain LM, Valtschanoff JG, Park CS, Maglione C, Gupton SL, A novel Netrin-1-sensitive mechanism promotes local SNARE-mediated exocytosis during axon branching. J Cell Biol. 2014 Apr 28;205(2):217-32 |
Trim24 tripartite motif-containing 24 (Synonyms: A130082H20Rik, D430004I05Rik, Tif1a, TIF1alpha) | |
Results | Reference |
1* | J:55698 Remboutsika E, Lutz Y, Gansmuller A, Vonesch JL, Losson R, Chambon P, The putative nuclear receptor mediator TIF1alpha is tightly associated with euchromatin. J Cell Sci. 1999 Jun;112(Pt 11):1671-83 |
Trim25 tripartite motif-containing 25 (Synonyms: estrogen-responsive finger protein, Zfp147) | |
Results | Reference |
1* | J:29351 Orimo A, Inoue S, Ikeda K, Noji S, Muramatsu M, Molecular cloning, structure, and expression of mouse estrogen-responsive finger protein Efp. Co-localization with estrogen receptor mRNA in target organs. J Biol Chem. 1995 Oct 13;270(41):24406-13 |
Trim28 tripartite motif-containing 28 (Synonyms: KAP-1, KRIP-1, MommeD9, Tif1b) | |
Results | Reference |
1 | J:265843 Chowdhury R, Laboissonniere LA, Wester AK, Muller M, Trimarchi JM, The Trim family of genes and the retina: Expression and functional characterization. PLoS One. 2018;13(9):e0202867 |
Trim32 tripartite motif-containing 32 (Synonyms: 1810045E12Rik, 3f3, BBS11, Zfp117) | |
Results | Reference |
1 | J:265843 Chowdhury R, Laboissonniere LA, Wester AK, Muller M, Trimarchi JM, The Trim family of genes and the retina: Expression and functional characterization. PLoS One. 2018;13(9):e0202867 |
1 | J:145909 Schwamborn JC, Berezikov E, Knoblich JA, The TRIM-NHL protein TRIM32 activates microRNAs and prevents self-renewal in mouse neural progenitors. Cell. 2009 Mar 6;136(5):913-25 |
1 | J:320749 Sun YY, Chen WJ, Huang ZP, Yang G, Wu ML, Xu DE, Yang WL, Luo YC, Xiao ZC, Xu RX, Ma QH, TRIM32 Deficiency Impairs the Generation of Pyramidal Neurons in Developing Cerebral Cortex. Cells. 2022 Jan 28;11(3) |
Trim33 tripartite motif-containing 33 (Synonyms: 8030451N04Rik, Ecto, ectodermin, mKIAA1113, Tif1g) | |
Results | Reference |
1 | J:91317 Okubo T, Hogan BL, Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm. J Biol. 2004;3(3):11 |
1 | J:91900 Yan KP, Dolle P, Mark M, Lerouge T, Wendling O, Chambon P, Losson R, Molecular cloning, genomic structure, and expression analysis of the mouse transcriptional intermediary factor 1 gamma gene. Gene. 2004 Jun 9;334:3-13 |
Trim36 tripartite motif-containing 36 (Synonyms: D18Wsu100e, Haprin) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Trim41 tripartite motif-containing 41 (Synonyms: MGC:28280, RINCK) | |
Results | Reference |
1 | J:325726 Oura S, Hino T, Satoh T, Noda T, Koyano T, Isotani A, Matsuyama M, Akira S, Ishiguro KI, Ikawa M, Trim41 is required to regulate chromosome axis protein dynamics and meiosis in male mice. PLoS Genet. 2022 Jun;18(6):e1010241 |
Trim44 tripartite motif-containing 44 (Synonyms: DIPB, Mc7) | |
Results | Reference |
1 | J:265843 Chowdhury R, Laboissonniere LA, Wester AK, Muller M, Trimarchi JM, The Trim family of genes and the retina: Expression and functional characterization. PLoS One. 2018;13(9):e0202867 |
Trim46 tripartite motif-containing 46 (Synonyms: TRIFIC) | |
Results | Reference |
1 | J:265843 Chowdhury R, Laboissonniere LA, Wester AK, Muller M, Trimarchi JM, The Trim family of genes and the retina: Expression and functional characterization. PLoS One. 2018;13(9):e0202867 |
Trim50 tripartite motif-containing 50 | |
Results | Reference |
1* | J:316637 Strogantsev R, Krueger F, Yamazawa K, Shi H, Gould P, Goldman-Roberts M, McEwen K, Sun B, Pedersen R, Ferguson-Smith AC, Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression. Genome Biol. 2015 May 30;16:112 |
Trim54 tripartite motif-containing 54 (Synonyms: 4930486E09Rik, 4930566I02Rik, MuRF3, Rnf30) | |
Results | Reference |
1* | J:63980 Spencer JA, Eliazer S, Ilaria RL Jr, Richardson JA, Olson EN, Regulation of microtubule dynamics and myogenic differentiation by MURF, a striated muscle RING-finger protein. J Cell Biol. 2000 Aug 21;150(4):771-84 |
Trim55 tripartite motif-containing 55 (Synonyms: D830041C10Rik, Murf2) | |
Results | Reference |
1* | J:170578 Perera S, Holt MR, Mankoo BS, Gautel M, Developmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover. Dev Biol. 2011 Mar 1;351(1):46-61 |
Trim62 tripartite motif-containing 62 (Synonyms: 6330414G21Rik, Dear1) | |
Results | Reference |
1 | J:265843 Chowdhury R, Laboissonniere LA, Wester AK, Muller M, Trimarchi JM, The Trim family of genes and the retina: Expression and functional characterization. PLoS One. 2018;13(9):e0202867 |
Trim63 tripartite motif-containing 63 (Synonyms: MuRF1, Rnf28) | |
Results | Reference |
1 | J:229482 Nagandla H, Lopez S, Yu W, Rasmussen TL, Tucker HO, Schwartz RJ, Stewart MD, Defective myogenesis in the absence of the muscle-specific lysine methyltransferase SMYD1. Dev Biol. 2016 Feb 1;410(1):86-97 |
Trim71 tripartite motif-containing 71 (Synonyms: 2610206G21Rik, 636931, lin-41, Lin41, LOC382112, mlin-41, mLin41) | |
Results | Reference |
1 | J:183920 Chen J, Lai F, Niswander L, The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling. Genes Dev. 2012 Apr 15;26(8):803-15 |
1* | J:102849 Schulman BR, Esquela-Kerscher A, Slack FJ, Reciprocal expression of lin-41 and the microRNAs let-7 and mir-125 during mouse embryogenesis. Dev Dyn. 2005 Dec;234(4):1046-54 |
Trim72 tripartite motif-containing 72 (Synonyms: MG53, mitsugumin 53) | |
Results | Reference |
1* | J:186368 Lee CS, Yi JS, Jung SY, Kim BW, Lee NR, Choo HJ, Jang SY, Han J, Chi SG, Park M, Lee JH, Ko YG, TRIM72 negatively regulates myogenesis via targeting insulin receptor substrate-1. Cell Death Differ. 2010 Aug;17(8):1254-65 |
Trio triple functional domain (PTPRF interacting) (Synonyms: 6720464I07Rik, Solo) | |
Results | Reference |
1 | J:273200 Landin Malt A, Dailey Z, Holbrook-Rasmussen J, Zheng Y, Hogan A, Du Q, Lu X, Par3 is essential for the establishment of planar cell polarity of inner ear hair cells. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4999-5008 |
1 | J:321518 Sun X, Wang L, Wei C, Sun M, Li Q, Meng H, Yue W, Zhang D, Li J, Dysfunction of Trio GEF1 involves in excitatory/inhibitory imbalance and autism-like behaviors through regulation of interneuron migration. Mol Psychiatry. 2021 Dec;26(12):7621-7640 |
Triobp TRIO and F-actin binding protein (Synonyms: EST478828, Mus EST 478828, Tara) | |
Results | Reference |
1 | J:200106 Duncan JS, Fritzsch B, Continued expression of GATA3 is necessary for cochlear neurosensory development. PLoS One. 2013;8(4):e62046 |
Trip6 thyroid hormone receptor interactor 6 | |
Results | Reference |
1* | J:200664 Cuppen E, van Ham M, Wansink DG, de Leeuw A, Wieringa B, Hendriks W, The zyxin-related protein TRIP6 interacts with PDZ motifs in the adaptor protein RIL and the protein tyrosine phosphatase PTP-BL. Eur J Cell Biol. 2000 Apr;79(4):283-93 |
2* | J:215602 Lai YJ, Li MY, Yang CY, Huang KH, Tsai JC, Wang TW, TRIP6 regulates neural stem cell maintenance in the postnatal mammalian subventricular zone. Dev Dyn. 2014 Sep;243(9):1130-42 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:312425 Shukla S, Haenold R, Urbanek P, Frappart L, Monajembashi S, Grigaravicius P, Nagel S, Min WK, Tapias A, Kassel O, Heuer H, Wang ZQ, Ploubidou A, Herrlich P, TRIP6 functions in brain ciliogenesis. Nat Commun. 2021 Oct 7;12(1):5887 |
Trip10 thyroid hormone receptor interactor 10 (Synonyms: Cip4) | |
Results | Reference |
1* | J:182499 Saengsawang W, Mitok K, Viesselmann C, Pietila L, Lumbard DC, Corey SJ, Dent EW, The F-BAR Protein CIP4 Inhibits Neurite Formation by Producing Lamellipodial Protrusions. Curr Biol. 2012 Mar 20;22(6):494-501 |
Trip12 thyroid hormone receptor interactor 12 (Synonyms: 1110036I07Rik, 6720416K24Rik, Gtl6) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Trmt1l tRNA methyltransferase 1 like (Synonyms: 1190005F20Rik, Trm1-like) | |
Results | Reference |
1* | J:118222 Vauti F, Goller T, Beine R, Becker L, Klopstock T, Holter SM, Wurst W, Fuchs H, Gailus-Durner V, de Angelis MH, Arnold HH, The mouse Trm1-like gene is expressed in neural tissues and plays a role in motor coordination and exploratory behaviour. Gene. 2007 Mar 15;389(2):174-85 |
Trmt112 tRNA methyltransferase 11-2 (Synonyms: 0610038D11Rik, Trm112p) | |
Results | Reference |
2* | J:186320 Gu T, He H, Zhang Y, Han Z, Hou G, Zeng T, Liu Q, Wu Q, Trmt112 gene expression in mouse embryonic development. Acta Histochem Cytochem. 2012 Apr 26;45(2):113-9 |
Trnp1 TMF1-regulated nuclear protein 1 (Synonyms: 2300002D11Rik) | |
Results | Reference |
1* | J:197030 Stahl R, Walcher T, De Juan Romero C, Pilz GA, Cappello S, Irmler M, Sanz-Aquela JM, Beckers J, Blum R, Borrell V, Gotz M, Trnp1 regulates expansion and folding of the mammalian cerebral cortex by control of radial glial fate. Cell. 2013 Apr 25;153(3):535-49 |
Trp53 transformation related protein 53 (Synonyms: p44, p53) | |
Results | Reference |
1 | J:183431 Aboudehen K, Hilliard S, Saifudeen Z, El-Dahr SS, Mechanisms of p53 activation and physiological relevance in the developing kidney. Am J Physiol Renal Physiol. 2012 Apr;302(8):F928-40 |
1 | J:299451 Atkins A, Xu MJ, Li M, Rogers NP, Pryzhkova MV, Jordan PW, SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. Elife. 2020 Nov 17;9:e61171 |
1* | J:148991 Barkic M, Crnomarkovic S, Grabusic K, Bogetic I, Panic L, Tamarut S, Cokaric M, Jeric I, Vidak S, Volarevic S, The p53 tumor suppressor causes congenital malformations in Rpl24-deficient mice and promotes their survival. Mol Cell Biol. 2009 May;29(10):2489-504 |
1 | J:300487 Chai G, Webb A, Li C, Antaki D, Lee S, Breuss MW, Lang N, Stanley V, Anzenberg P, Yang X, Marshall T, Gaffney P, Wierenga KJ, Chung BH, Tsang MH, Pais LS, Lovgren AK, VanNoy GE, Rehm HL, Mirzaa G, Leon E, Diaz J, Neumann A, Kalverda AP, Manfield IW, Parry DA, Logan CV, Johnson CA, Bonthron DT, Valleley EMA, Issa MY, Abdel-Ghafar SF, Abdel-Hamid MS, Jennings P, Zaki MS, Sheridan E, Gleeson JG, Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 Jan 20;109(2):241-256.e9 |
1* | J:211539 Chen Y, Gridley T, Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis. J Bone Miner Res. 2013 Jun;28(6):1412-21 |
1 | J:206141 Eguren M, Porlan E, Manchado E, Garcia-Higuera I, Canamero M, Farinas I, Malumbres M, The APC/C cofactor Cdh1 prevents replicative stress and p53-dependent cell death in neural progenitors. Nat Commun. 2013;4:2880 |
1 | J:337771 El-Saafin F, Bergamasco MI, Chen Y, May RE, Esakky P, Hediyeh-Zadeh S, Dixon M, Wilcox S, Davis MJ, Strasser A, Smyth GK, Thomas T, Voss AK, Loss of TAF8 causes TFIID dysfunction and p53-mediated apoptotic neuronal cell death. Cell Death Differ. 2022 May;29(5):1013-1027 |
1 | J:216295 Garnatz AS, Gao Z, Broman M, Martens S, Earley JU, Svensson EC, FOG-2 mediated recruitment of the NuRD complex regulates cardiomyocyte proliferation during heart development. Dev Biol. 2014 Nov 1;395(1):50-61 |
1 | J:313928 Kim EJ, Lee JE, Yoon S, Lee DJ, Mai HN, Ida-Yonemochi H, Choi J, Jung HS, Hypoxia-Responsive Oxygen Nanobubbles for Tissues-Targeted Delivery in Developing Tooth Germs. Front Cell Dev Biol. 2021;9:626224 |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
1 | J:181920 Lee Y, Shull ER, Frappart PO, Katyal S, Enriquez-Rios V, Zhao J, Russell HR, Brown EJ, McKinnon PJ, ATR maintains select progenitors during nervous system development. EMBO J. 2012 Mar 7;31(5):1177-89 |
1 | J:352165 Lin Y, Tang W, Huang P, Wang Z, Duan L, Jia C, Sun R, Liu L, Shen J, Denticleless E3 ubiquitin protein ligase (DTL) maintains the proliferation and differentiation of epidermis and hair follicles during skin development. Dev Dyn. 2024 Jul;253(7):635-647 |
1 | J:210514 Martinez P, Ferrara-Romeo I, Flores JM, Blasco MA, Essential role for the TRF2 telomere protein in adult skin homeostasis. Aging Cell. 2014 Aug;13(4):656-68 |
1 | J:185038 Martinez P, Flores JM, Blasco MA, 53BP1 deficiency combined with telomere dysfunction activates ATR-dependent DNA damage response. J Cell Biol. 2012 Apr 16;197(2):283-300 |
1 | J:261834 Maskell LJ, Qamar K, Babakr AA, Hawkins TA, Heads RJ, Budhram-Mahadeo VS, Essential but partially redundant roles for POU4F1/Brn-3a and POU4F2/Brn-3b transcription factors in the developing heart. Cell Death Dis. 2017 Jun 8;8(6):e2861 |
1* | J:60700 Matsui Y, Nagano R, Obinata M, Apoptosis of fetal testicular cells is regulated by both p53-dependent and independent mechanisms. Mol Reprod Dev. 2000 Apr;55(4):399-405 |
1 | J:152818 Melnick M, Phair RD, Lapidot SA, Jaskoll T, Salivary gland branching morphogenesis: a quantitative systems analysis of the Eda/Edar/NFkappaB paradigm. BMC Dev Biol. 2009;9:32 |
1 | J:97328 Nishio S, Hatano M, Nagata M, Horie S, Koike T, Tokuhisa T, Mochizuki T, Pkd1 regulates immortalized proliferation of renal tubular epithelial cells through p53 induction and JNK activation. J Clin Invest. 2005 Apr 1;115(4):910-918 |
1 | J:166316 Saifudeen Z, Dipp S, Stefkova J, Yao X, Lookabaugh S, El-Dahr SS, p53 regulates metanephric development. J Am Soc Nephrol. 2009 Nov;20(11):2328-37 |
1* | J:2003 Schmid P, Lorenz A, Hameister H, Montenarh M, Expression of p53 during mouse embryogenesis. Development. 1991 Nov;113(3):857-65 |
1* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1 | J:208719 Tsai MJ, Yang-Yen HF, Chiang MK, Wang MJ, Wu SS, Chen SH, TCTP is essential for beta-cell proliferation and mass expansion during development and beta-cell adaptation in response to insulin resistance. Endocrinology. 2014 Feb;155(2):392-404 |
1 | J:206929 Watson LA, Wang X, Elbert A, Kernohan KD, Galjart N, Berube NG, Dual Effect of CTCF Loss on Neuroprogenitor Differentiation and Survival. J Neurosci. 2014 Feb 19;34(8):2860-70 |
1* | J:261042 Welcker D, Jain M, Khurshid S, Jokic M, Hohne M, Schmitt A, Frommolt P, Niessen CM, Spiro J, Persigehl T, Wittersheim M, Buttner R, Fanciulli M, Schermer B, Reinhardt HC, Benzing T, Hopker K, AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer. Oncogene. 2018 Mar;37(11):1503-1518 |
1 | J:241249 Xue Y, Raharja A, Sim W, Wong ES, Rahmat SA, Lane DP, The hot-spot p53R172H mutant promotes formation of giant spermatogonia triggered by DNA damage. Oncogene. 2017 Apr 06;36(14):2002-2013 |
Trp53bp1 transformation related protein 53 binding protein 1 (Synonyms: 53BP1, p53BP1) | |
Results | Reference |
1* | J:347585 Leon NY, Le TNU, Garvie A, Wong LH, Bagheri-Fam S, Harley VR, Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. iScience. 2024 May 17;27(5):109629 |
1 | J:333324 Tominaga K, Sakashita E, Kasashima K, Kuroiwa K, Nagao Y, Iwamori N, Endo H, Tip60/KAT5 Histone Acetyltransferase Is Required for Maintenance and Neurogenesis of Embryonic Neural Stem Cells. Int J Mol Sci. 2023 Jan 20;24(3) |
Trp53inp1 transformation related protein 53 inducible nuclear protein 1 (Synonyms: 2700057G22Rik, SIP, SIP18, SIP27, Stinp, Teap, Tp53inp1) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Trp63 transformation related protein 63 (Synonyms: deltaNp63, KET protein, p51/p63, p63, p73L, TAp63, Trp53rp1) | |
Results | Reference |
1 | J:276773 Beeler JS, Marshall CB, Gonzalez-Ericsson PI, Shaver TM, Santos Guasch GL, Lea ST, Johnson KN, Jin H, Venters BJ, Sanders ME, Pietenpol JA, p73 regulates epidermal wound healing and induced keratinocyte programming. PLoS One. 2019;14(6):e0218458 |
1 | J:176604 Bell SM, Zhang L, Mendell A, Xu Y, Haitchi HM, Lessard JL, Whitsett JA, Kruppel-like factor 5 is required for formation and differentiation of the bladder urothelium. Dev Biol. 2011 Oct 1;358(1):79-90 |
1 | J:276488 Bilodeau M, Shojaie S, Ackerley C, Post M, Rossant J, Identification of a proximal progenitor population from murine fetal lungs with clonogenic and multilineage differentiation potential. Stem Cell Reports. 2014 Oct 14;3(4):634-49 |
1 | J:262819 Bohnenpoll T, Feraric S, Nattkemper M, Weiss AC, Rudat C, Meuser M, Trowe MO, Kispert A, Diversification of Cell Lineages in Ureter Development. J Am Soc Nephrol. 2017 Jun;28(6):1792-1801 |
1 | J:244068 Bohnenpoll T, Wittern AB, Mamo TM, Weiss AC, Rudat C, Kleppa MJ, Schuster-Gossler K, Wojahn I, Ludtke TH, Trowe MO, Kispert A, A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development. PLoS Genet. 2017 Aug;13(8):e1006951 |
1 | J:158529 Burgess D, Zhang Y, Siefker E, Vaca R, Kuracha MR, Reneker L, Overbeek PA, Govindarajan V, Activated Ras alters lens and corneal development through induction of distinct downstream targets. BMC Dev Biol. 2010;10:13 |
1 | J:309371 Chilukuri RV, Patel VK, Martinez M, Guyden JC, Samms MD, The Antigenic Determinant That Defines Thymic Nurse Cells Is Expressed by Thymic Epithelial Progenitor Cells. Front Cell Dev Biol. 2014 Apr 28;2(13) |
1* | J:288446 Christians A, Weiss AC, Martens H, Klopf MG, Hennies I, Haffner D, Kispert A, Weber RG, Inflammation-like changes in the urothelium of Lifr-deficient mice and LIFR-haploinsufficient humans with urinary tract anomalies. Hum Mol Genet. 2020 May 8;29(7):1192-1204 |
1 | J:330942 Chu Q, Yao C, Qi X, Stripp BR, Tang N, STK11 is required for the normal program of ciliated cell differentiation in airways. Cell Discov. 2019;5:36 |
1 | J:130204 Cook C, Vezina CM, Allgeier SH, Shaw A, Yu M, Peterson RE, Bushman W, Noggin is required for normal lobe patterning and ductal budding in the mouse prostate. Dev Biol. 2007 Dec 1;312(1):217-30 |
1* | J:121517 Danielian PS, Bender Kim CF, Caron AM, Vasile E, Bronson RT, Lees JA, E2f4 is required for normal development of the airway epithelium. Dev Biol. 2007 May 15;305(2):564-76 |
1 | J:259661 De Groote P, Tran HT, Fransen M, Tanghe G, Urwyler C, De Craene B, Leurs K, Gilbert B, Van Imschoot G, De Rycke R, Guerin CJ, Holland P, Berx G, Vandenabeele P, Lippens S, Vleminckx K, Declercq W, A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes. Cell Death Differ. 2015 Jun;22(6):1012-24 |
1 | J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767 |
1 | J:207252 Drosten M, Lechuga CG, Barbacid M, Ras signaling is essential for skin development. Oncogene. 2014 May 29;33(22):2857-65 |
1 | J:260456 Duteil D, Tourrette Y, Eberlin A, Willmann D, Patel D, Friedrichs N, Muller JM, Schule R, The histone acetyltransferase inhibitor Nir regulates epidermis development. Development. 2018 Mar 21;145(6):dev158543 |
1 | J:177729 Fessing MY, Mardaryev AN, Gdula MR, Sharov AA, Sharova TY, Rapisarda V, Gordon KB, Smorodchenko AD, Poterlowicz K, Ferone G, Kohwi Y, Missero C, Kohwi-Shigematsu T, Botchkarev VA, p63 regulates Satb1 to control tissue-specific chromatin remodeling during development of the epidermis. J Cell Biol. 2011 Sep 19;194(6):825-39 |
1 | J:193630 Fujimoto A, Kurban M, Nakamura M, Farooq M, Fujikawa H, Kibbi AG, Ito M, Dahdah M, Matta M, Diab H, Shimomura Y, GJB6, of which mutations underlie Clouston syndrome, is a potential direct target gene of p63. J Dermatol Sci. 2013 Feb;69(2):159-66 |
2 | J:199282 Gunschmann C, Stachelscheid H, Akyuz MD, Schmitz A, Missero C, Bruning JC, Niessen CM, Insulin/IGF-1 Controls Epidermal Morphogenesis via Regulation of FoxO-Mediated p63 Inhibition. Dev Cell. 2013 Jul 29;26(2):176-87 |
1* | J:136080 Guttormsen J, Koster MI, Stevens JR, Roop DR, Williams T, Winger QA, Disruption of epidermal specific gene expression and delayed skin development in AP-2 gamma mutant mice. Dev Biol. 2008 May 1;317(1):187-95 |
1 | J:222425 Harada M, Omori A, Nakahara C, Nakagata N, Akita K, Yamada G, Tissue-specific roles of FGF signaling in external genitalia development. Dev Dyn. 2015 Jun;244(6):759-73 |
1 | J:197815 Hashimoto S, Chen H, Que J, Brockway BL, Drake JA, Snyder JC, Randell SH, Stripp BR, beta-Catenin-SOX2 signaling regulates the fate of developing airway epithelium. J Cell Sci. 2012 Feb 15;125(Pt 4):932-42 |
1 | J:112460 Hatsell SJ, Cowin P, Gli3-mediated repression of Hedgehog targets is required for normal mammary development. Development. 2006 Sep;133(18):3661-70 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:182873 Jheon AH, Mostowfi P, Snead ML, Ihrie RA, Sone E, Pramparo T, Attardi LD, Klein OD, PERP regulates enamel formation via effects on cell-cell adhesion and gene expression. J Cell Sci. 2011 Mar 1;124(Pt 5):745-54 |
1 | J:252735 Jiang M, Li H, Zhang Y, Yang Y, Lu R, Liu K, Lin S, Lan X, Wang H, Wu H, Zhu J, Zhou Z, Xu J, Lee DK, Zhang L, Lee YC, Yuan J, Abrams JA, Wang TC, Sepulveda AR, Wu Q, Chen H, Sun X, She J, Chen X, Que J, Transitional basal cells at the squamous-columnar junction generate Barrett's oesophagus. Nature. 2017 Oct 26;550(7677):529-533 |
1* | J:169680 Karni-Schmidt O, Castillo-Martin M, Shen TH, Gladoun N, Domingo-Domenech J, Sanchez-Carbayo M, Li Y, Lowe S, Prives C, Cordon-Cardo C, Distinct Expression Profiles of p63 Variants during Urothelial Development and Bladder Cancer Progression. Am J Pathol. 2011 Mar;178(3):1350-60 |
1 | J:308704 Kiyokawa H, Yamaoka A, Matsuoka C, Tokuhara T, Abe T, Morimoto M, Airway basal stem cells reutilize the embryonic proliferation regulator, Tgfbeta-Id2 axis, for tissue regeneration. Dev Cell. 2021 Jul 12;56(13):1917-1929.e9 |
1* | J:100707 Kurita T, Cunha GR, Robboy SJ, Mills AA, Medina RT, Differential expression of p63 isoforms in female reproductive organs. Mech Dev. 2005 Sep;122(9):1043-55 |
1 | J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522 |
1 | J:168590 LeBoeuf M, Terrell A, Trivedi S, Sinha S, Epstein JA, Olson EN, Morrisey EE, Millar SE, Hdac1 and Hdac2 act redundantly to control p63 and p53 functions in epidermal progenitor cells. Dev Cell. 2010 Dec 14;19(6):807-18 |
1* | J:250161 Lee AJ, Polgar N, Napoli JA, Lui VH, Tamashiro KK, Fujimoto BA, Thompson KS, Fogelgren B, Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy. Sci Rep. 2016 Aug 11;6:31137 |
1 | J:338836 Li Q, Jiao J, Heng Y, Lu Q, Zheng Y, Li H, Cai J, Mei M, Bao S, Prmt5 promotes ciliated cell specification of airway epithelial progenitors via transcriptional inhibition of Tp63. J Biol Chem. 2023 Jun 24;299(8):104964 |
1 | J:352165 Lin Y, Tang W, Huang P, Wang Z, Duan L, Jia C, Sun R, Liu L, Shen J, Denticleless E3 ubiquitin protein ligase (DTL) maintains the proliferation and differentiation of epidermis and hair follicles during skin development. Dev Dyn. 2024 Jul;253(7):635-647 |
1 | J:219800 Lungova V, Verheyden JM, Herriges J, Sun X, Thibeault SL, Ontogeny of the mouse vocal fold epithelium. Dev Biol. 2015 Mar 15;399(2):263-82 |
1 | J:243772 Mamo TM, Wittern AB, Kleppa MJ, Bohnenpoll T, Weiss AC, Kispert A, BMP4 uses several different effector pathways to regulate proliferation and differentiation in the epithelial and mesenchymal tissue compartments of the developing mouse ureter. Hum Mol Genet. 2017 Sep 15;26(18):3553-3563 |
1 | J:210514 Martinez P, Ferrara-Romeo I, Flores JM, Blasco MA, Essential role for the TRF2 telomere protein in adult skin homeostasis. Aging Cell. 2014 Aug;13(4):656-68 |
1* | J:316269 Mehta V, Schmitz CT, Keil KP, Joshi PS, Abler LL, Lin TM, Taketo MM, Sun X, Vezina CM, Beta-catenin (CTNNB1) induces Bmp expression in urogenital sinus epithelium and participates in prostatic bud initiation and patterning. Dev Biol. 2013 Apr 15;376(2):125-35 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1 | J:161749 Mill P, Lee AW, Fukata Y, Tsutsumi R, Fukata M, Keighren M, Porter RM, McKie L, Smyth I, Jackson IJ, Palmitoylation regulates epidermal homeostasis and hair follicle differentiation. PLoS Genet. 2009 Nov;5(11):e1000748 |
1 | J:161645 Moretti F, Marinari B, Lo Iacono N, Botti E, Giunta A, Spallone G, Garaffo G, Vernersson-Lindahl E, Merlo G, Mills AA, Ballaro C, Alema S, Chimenti S, Guerrini L, Costanzo A, A regulatory feedback loop involving p63 and IRF6 links the pathogenesis of 2 genetically different human ectodermal dysplasias. J Clin Invest. 2010 May 3;120(5):1570-7 |
1 | J:238903 Mori M, Mahoney JE, Stupnikov MR, Paez-Cortez JR, Szymaniak AD, Varelas X, Herrick DB, Schwob J, Zhang H, Cardoso WV, Notch3-Jagged signaling controls the pool of undifferentiated airway progenitors. Development. 2015 Jan 15;142(2):258-67 |
2* | J:85888 Nakamuta N, Kobayashi S, Expression of p63 in the testis of mouse embryos. J Vet Med Sci. 2003 Aug;65(8):853-6 |
1* | J:297164 Nie X, Zheng J, Cruciger M, Yang P, Mao JJ, mTOR plays a pivotal role in multiple processes of enamel organ development principally through the mTORC1 pathway and in part via regulating cytoskeleton dynamics. Dev Biol. 2020 Nov 1;467(1-2):77-87 |
1* | J:197594 Okubo T, Clark C, Hogan BL, Cell lineage mapping of taste bud cells and keratinocytes in the mouse tongue and soft palate. Stem Cells. 2009 Feb;27(2):442-50 |
1 | J:173538 Packard A, Schnittke N, Romano RA, Sinha S, Schwob JE, {Delta}Np63 regulates stem cell dynamics in the Mammalian olfactory epithelium. J Neurosci. 2011 Jun 15;31(24):8748-59 |
2* | J:326663 Qasrawi F, Meuser M, Lehnhoff F, Schulte M, Kispert A, S100A1 expression characterizes terminally differentiated superficial cells in the urothelium of the murine bladder and ureter. Histochem Cell Biol. 2022 Jun 1; |
1 | J:180027 Restivo G, Nguyen BC, Dziunycz P, Ristorcelli E, Ryan RJ, Ozuysal OY, Di Piazza M, Radtke F, Dixon MJ, Hofbauer GF, Lefort K, Dotto GP, IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes. EMBO J. 2011 Nov 16;30(22):4571-85 |
1 | J:149319 Romano RA, Ortt K, Birkaya B, Smalley K, Sinha S, An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate. PLoS One. 2009;4(5):e5623 |
1 | J:168262 Romano RA, Smalley K, Liu S, Sinha S, Abnormal hair follicle development and altered cell fate of follicular keratinocytes in transgenic mice expressing DeltaNp63alpha. Development. 2010 May;137(9):1431-9 |
1 | J:301269 Sankoda N, Tanabe W, Tanaka A, Shibata H, Woltjen K, Chiba T, Haga H, Sakai Y, Mandai M, Yamamoto T, Yamada Y, Uemoto S, Kawaguchi Y, Epithelial expression of Gata4 and Sox2 regulates specification of the squamous-columnar junction via MAPK/ERK signaling in mice. Nat Commun. 2021 Jan 25;12(1):560 |
1 | J:217677 Snitow ME, Li S, Morley MP, Rathi K, Lu MM, Kadzik RS, Stewart KM, Morrisey EE, Ezh2 represses the basal cell lineage during lung endoderm development. Development. 2015 Jan 1;142(1):108-17 |
1 | J:356070 Song EC, Min S, Oyelakin A, Smalley K, Bard JE, Liao L, Xu J, Romano RA, Genetic and scRNA-seq Analysis Reveals Distinct Cell Populations that Contribute to Salivary Gland Development and Maintenance. Sci Rep. 2018 Sep 19;8(1):14043 |
1* | J:247327 Spiller CM, Wilhelm D, Jans DA, Bowles J, Koopman P, Mice Lacking Hbp1 Function Are Viable and Fertile. PLoS One. 2017;12(1):e0170576 |
1 | J:239794 Szymaniak AD, Mahoney JE, Cardoso WV, Varelas X, Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap. Dev Cell. 2015 Aug 10;34(3):283-96 |
1 | J:266598 Ustiyan V, Bolte C, Zhang Y, Han L, Xu Y, Yutzey KE, Zorn AM, Kalin TV, Shannon JM, Kalinichenko VV, FOXF1 transcription factor promotes lung morphogenesis by inducing cellular proliferation in fetal lung mesenchyme. Dev Biol. 2018 Nov 1;443(1):50-63 |
1* | J:294158 Vernersson Lindahl E, Garcia EL, Mills AA, An allelic series of Trp63 mutations defines TAp63 as a modifier of EEC syndrome. Am J Med Genet A. 2013 Aug;161A(8):1961-71 |
1 | J:338452 Wang D, Li H, Chandel NS, Dou Y, Yi R, MOF-mediated histone H4 Lysine 16 acetylation governs mitochondrial and ciliary functions by controlling gene promoters. Nat Commun. 2023 Jul 21;14(1):4404 |
3 | J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26 |
1 | J:326460 Yang R, Li R, Huang Z, Zuo Y, Yue H, Wu H, Gu F, Wang F, He M, Bian Z, Mycn deficiency underlies the development of orofacial clefts in mice and humans. Hum Mol Genet. 2022 Mar 3;31(5):803-815 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
1* | J:173972 Zhao H, Li S, Han D, Kaartinen V, Chai Y, Alk5-mediated transforming growth factor beta signaling acts upstream of fibroblast growth factor 10 to regulate the proliferation and maintenance of dental epithelial stem cells. Mol Cell Biol. 2011 May;31(10):2079-89 |
Trp73 transformation related protein 73 (Synonyms: deltaNp73, p73, TAp73) | |
Results | Reference |
2 | J:291525 Amelio I, Panatta E, Niklison-Chirou MV, Steinert JR, Agostini M, Morone N, Knight RA, Melino G, The C terminus of p73 is essential for hippocampal development. Proc Natl Acad Sci U S A. 2020 Jul 7;117(27):15694-15701 |
1 | J:276773 Beeler JS, Marshall CB, Gonzalez-Ericsson PI, Shaver TM, Santos Guasch GL, Lea ST, Johnson KN, Jin H, Venters BJ, Sanders ME, Pietenpol JA, p73 regulates epidermal wound healing and induced keratinocyte programming. PLoS One. 2019;14(6):e0218458 |
1 | J:125693 Hanashima C, Fernandes M, Hebert JM, Fishell G, The role of Foxg1 and dorsal midline signaling in the generation of Cajal-Retzius subtypes. J Neurosci. 2007 Oct 10;27(41):11103-11 |
1 | J:134970 Inoue T, Ogawa M, Mikoshiba K, Aruga J, Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly. J Neurosci. 2008 Apr 30;28(18):4712-25 |
1* | J:105760 Swetloff A, Ferretti P, Changes in E2F5 intracellular localization in mouse and human choroid plexus epithelium with development. Int J Dev Biol. 2005;49(7):859-65 |
1 | J:221658 Vithayathil J, Pucilowska J, Goodnough LH, Atit RP, Landreth GE, Dentate Gyrus Development Requires ERK Activity to Maintain Progenitor Population and MAPK Pathway Feedback Regulation. J Neurosci. 2015 Apr 29;35(17):6836-48 |
Trpa1 transient receptor potential cation channel, subfamily A, member 1 (Synonyms: ANKTM1) | |
Results | Reference |
1 | J:106971 Chen CL, Broom DC, Liu Y, de Nooij JC, Li Z, Cen C, Samad OA, Jessell TM, Woolf CJ, Ma Q, Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain. Neuron. 2006 Feb 2;49(3):365-77 |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
Trpc1 transient receptor potential cation channel, subfamily C, member 1 (Synonyms: Mtrp1, Trp1, Trrp1) | |
Results | Reference |
1 | J:147315 Boisseau S, Kunert-Keil C, Lucke S, Bouron A, Heterogeneous distribution of TRPC proteins in the embryonic cortex. Histochem Cell Biol. 2009 Mar;131(3):355-63 |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
Trpc2 transient receptor potential cation channel, subfamily C, member 2 (Synonyms: 3010009O07Rik, mTrp2, trp2, TRPC2a, TRPC2b, Trrp2) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
Trpc3 transient receptor potential cation channel, subfamily C, member 3 (Synonyms: Trcp3, Trp3, Trrp3) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
Trpc4 transient receptor potential cation channel, subfamily C, member 4 (Synonyms: CCE1, STRPC4, Trp4, Trrp4) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
1* | J:121911 Zechel S, Werner S, von Bohlen Und Halbach O, Distribution of TRPC4 in developing and adult murine brain. Cell Tissue Res. 2007 Jun;328(3):651-6 |
Trpc5 transient receptor potential cation channel, subfamily C, member 5 (Synonyms: CCE2, TRP5, Trrp5) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
2 | J:335863 Oda M, Yamamoto H, Matsumoto H, Ishizaki Y, Shibasaki K, TRPC5 regulates axonal outgrowth in developing retinal ganglion cells. Lab Invest. 2020 Feb;100(2):297-310 |
Trpc6 transient receptor potential cation channel, subfamily C, member 6 (Synonyms: mtrp6, Trrp6) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
1 | J:170449 Yamaguchi N, Chakraborty A, Pasek DA, Molkentin JD, Meissner G, Dysfunctional ryanodine receptor and cardiac hypertrophy: role of signaling molecules. Am J Physiol Heart Circ Physiol. 2011 Jun;300(6):H2187-95 |
Trpc7 transient receptor potential cation channel, subfamily C, member 7 (Synonyms: TRP7, Trrp8) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
Trpm1 transient receptor potential cation channel, subfamily M, member 1 (Synonyms: 4732499L03Rik, LTRPC1, melastatin, Mlsn1) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
Trpm2 transient receptor potential cation channel, subfamily M, member 2 (Synonyms: 9830168K16Rik, LTRPC2, TRPC7, Trrp7) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
Trpm3 transient receptor potential cation channel, subfamily M, member 3 (Synonyms: 6330504P12Rik, B930001P07Rik, LTRPC3, melastatin 2, MLSN2) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
Trpm4 transient receptor potential cation channel, subfamily M, member 4 (Synonyms: 1110030C19Rik, LTRPC4, TRPM4B) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
Trpm5 transient receptor potential cation channel, subfamily M, member 5 (Synonyms: 9430099A16Rik, Ltrpc5, Mtr1) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
1* | J:63702 Paulsen M, El-Maarri O, Engemann S, Strodicke M, Franck O, Davies K, Reinhardt R, Reik W, Walter J, Sequence conservation and variability of imprinting in the beckwith-wiedemann syndrome gene cluster in human and mouse. Hum Mol Genet. 2000 Jul 22;9(12):1829-41 |
1 | J:261444 Pyrski M, Eckstein E, Schmid A, Bufe B, Weiss J, Chubanov V, Boehm U, Zufall F, Trpm5 expression in the olfactory epithelium. Mol Cell Neurosci. 2017 Apr;80:75-88 |
1 | J:186296 Saqui-Salces M, Keeley TM, Grosse AS, Qiao XT, El-Zaatari M, Gumucio DL, Samuelson LC, Merchant JL, Gastric tuft cells express DCLK1 and are expanded in hyperplasia. Histochem Cell Biol. 2011 Aug;136(2):191-204 |
Trpm6 transient receptor potential cation channel, subfamily M, member 6 (Synonyms: CHAK2) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
1* | J:153718 Walder RY, Yang B, Stokes JB, Kirby PA, Cao X, Shi P, Searby CC, Husted RF, Sheffield VC, Mice defective in Trpm6 show embryonic mortality and neural tube defects. Hum Mol Genet. 2009 Nov 15;18(22):4367-75 |
Trpm7 transient receptor potential cation channel, subfamily M, member 7 (Synonyms: 2310022G15Rik, 4833414K03Rik, 5033407O22Rik, CHAK, CHAK1, Ltpr7, LTRPC7, TRP-PLIK) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
1 | J:286893 Ogata K, Tsumuraya T, Oka K, Shin M, Okamoto F, Kajiya H, Katagiri C, Ozaki M, Matsushita M, Okabe K, The crucial role of the TRPM7 kinase domain in the early stage of amelogenesis. Sci Rep. 2017 Dec 22;7(1):18099 |
Trpm8 transient receptor potential cation channel, subfamily M, member 8 (Synonyms: CMR1, Trp-p8, TRPP8) | |
Results | Reference |
1 | J:106971 Chen CL, Broom DC, Liu Y, de Nooij JC, Li Z, Cen C, Samad OA, Jessell TM, Woolf CJ, Ma Q, Runx1 determines nociceptive sensory neuron phenotype and is required for thermal and neuropathic pain. Neuron. 2006 Feb 2;49(3):365-77 |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
1* | J:186470 Lopes C, Liu Z, Xu Y, Ma Q, Tlx3 and runx1 act in combination to coordinate the development of a cohort of nociceptors, thermoceptors, and pruriceptors. J Neurosci. 2012 Jul 11;32(28):9706-15 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
Trps1 transcriptional repressor GATA binding 1 (Synonyms: D15Ertd586e, trichorhinophalangeal syndrome I (human)) | |
Results | Reference |
3* | J:130445 Fantauzzo KA, Bazzi H, Jahoda CA, Christiano AM, Dynamic expression of the zinc-finger transcription factor Trps1 during hair follicle morphogenesis and cycling. Gene Expr Patterns. 2008 Jan;8(2):51-7 |
1 | J:194118 Fantauzzo KA, Kurban M, Levy B, Christiano AM, Trps1 and its target gene Sox9 regulate epithelial proliferation in the developing hair follicle and are associated with hypertrichosis. PLoS Genet. 2012;8(11):e1003002 |
2* | J:141036 Fantauzzo KA, Tadin-Strapps M, You Y, Mentzer SE, Baumeister FA, Cianfarani S, Van Maldergem L, Warburton D, Sundberg JP, Christiano AM, A position effect on TRPS1 is associated with Ambras syndrome in humans and the Koala phenotype in mice. Hum Mol Genet. 2008 Nov 15;17(22):3539-51 |
1* | J:81315 Kunath M, Ludecke HJ, Vortkamp A, Expression of Trps1 during mouse embryonic development. Mech Dev. 2002 Dec;119 Suppl 1:S117-20 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
2 | J:149459 Wuelling M, Kaiser FJ, Buelens LA, Braunholz D, Shivdasani RA, Depping R, Vortkamp A, Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. Dev Biol. 2009 Apr 1;328(1):40-53 |
1 | J:283400 Wuelling M, Schneider S, Schrother VA, Waterkamp C, Hoffmann D, Vortkamp A, Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of chondrocyte hypertrophy. Dev Biol. 2020 Jan 1;457(1):104-118 |
Trpv1 transient receptor potential cation channel, subfamily V, member 1 (Synonyms: capsaicin receptor, OTRPC1, Vr1, VR-1) | |
Results | Reference |
1 | J:174523 Cavanaugh DJ, Chesler AT, Braz JM, Shah NM, Julius D, Basbaum AI, Restriction of transient receptor potential vanilloid-1 to the peptidergic subset of primary afferent neurons follows its developmental downregulation in nonpeptidergic neurons. J Neurosci. 2011 Jul 13;31(28):10119-27 |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
1 | J:114546 Funakoshi K, Nakano M, Atobe Y, Kadota T, Goris RC, Prenatal development of transient receptor potential vanilloid 1-expressing primary sensory projections to sacral autonomic preganglionic neurons. Neurosci Lett. 2006 Oct 30;407(3):230-3 |
1 | J:227268 Malenczyk K, Keimpema E, Piscitelli F, Calvigioni D, Bjorklund P, Mackie K, Di Marzo V, Hokfelt TG, Dobrzyn A, Harkany T, Fetal endocannabinoids orchestrate the organization of pancreatic islet microarchitecture. Proc Natl Acad Sci U S A. 2015 Nov 10;112(45):E6185-94 |
1 | J:145293 Wickramasinghe SR, Alvania RS, Ramanan N, Wood JN, Mandai K, Ginty DD, Serum response factor mediates NGF-dependent target innervation by embryonic DRG sensory neurons. Neuron. 2008 May 22;58(4):532-45 |
Trpv2 transient receptor potential cation channel, subfamily V, member 2 (Synonyms: OTRPC2, Vrl1, VRL-1) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
Trpv3 transient receptor potential cation channel, subfamily V, member 3 (Synonyms: 1110036I10Rik, Nh, VRL3) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
Trpv4 transient receptor potential cation channel, subfamily V, member 4 (Synonyms: 0610033B08Rik, OTRPC4, Trp12, VRL-2, VR-OAC, VROAC) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
Trpv5 transient receptor potential cation channel, subfamily V, member 5 (Synonyms: CaT2, ECaC1) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
Trpv6 transient receptor potential cation channel, subfamily V, member 6 (Synonyms: Cac, CAT, CaT1, Ecac2) | |
Results | Reference |
1 | J:307092 De Clercq K, Perez-Garcia V, Van Bree R, Pollastro F, Peeraer K, Voets T, Vriens J, Mapping the expression of transient receptor potential channels across murine placental development. Cell Mol Life Sci. 2021 Jun;78(11):4993-5014 |
Tsc1 TSC complex subunit 1 (Synonyms: hamartin, tuberous sclerosis 1) | |
Results | Reference |
1* | J:332849 Baskaran P, Mihaylov SR, Vinsland E, Shah K, Granat L, Ultanir SK, Tee AR, Murn J, Bateman JM, Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis. J Biol Chem. 2023 Jan;299(1):102788 |
Tsc2 TSC complex subunit 2 (Synonyms: Nafld, tuberin, tuberous sclerosis 2) | |
Results | Reference |
1 | J:232899 Moon UY, Park JY, Park R, Cho JY, Hughes LJ, McKenna J 3rd, Goetzl L, Cho SH, Crino PB, Gambello MJ, Kim S, Impaired Reelin-Dab1 Signaling Contributes to Neuronal Migration Deficits of Tuberous Sclerosis Complex. Cell Rep. 2015 Aug 11;12(6):965-78 |
1 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
1 | J:326480 Terry BK, Park R, Cho SH, Crino PB, Kim S, Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex. Hum Mol Genet. 2022 Jun 22;31(12):1979-1996 |
Tsc22d1 TSC22 domain family, member 1 (Synonyms: Egr5, Tgfb1i4, TSC-22) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Tsga10 testis specific 10 (Synonyms: 4933432N21Rik, Mtsga10) | |
Results | Reference |
1 | J:108998 Behnam B, Modarressi MH, Conti V, Taylor KE, Puliti A, Wolfe J, Expression of Tsga10 sperm tail protein in embryogenesis and neural development: from cilium to cell division. Biochem Biophys Res Commun. 2006 Jun 16;344(4):1102-10 |
Tshb thyroid stimulating hormone, beta subunit (Synonyms: thyrotropin) | |
Results | Reference |
1 | J:30290 Andersen B, Pearse RV 2nd, Jenne K, Sornson M, Lin SC, Bartke A, Rosenfeld MG, The Ames dwarf gene is required for Pit-1 gene activation. Dev Biol. 1995 Dec;172(2):495-503 |
1 | J:223814 Aujla PK, Bogdanovic V, Naratadam GT, Raetzman LT, Persistent expression of activated notch in the developing hypothalamus affects survival of pituitary progenitors and alters pituitary structure. Dev Dyn. 2015 Aug;244(8):921-34 |
1* | J:290740 Brachet C, Kozhemyakina EA, Boros E, Heinrichs C, Balikova I, Soblet J, Smits G, Vilain C, Mathers PH, Truncating RAX Mutations: Anophthalmia, Hypopituitarism, Diabetes Insipidus, and Cleft Palate in Mice and Men. J Clin Endocrinol Metab. 2019 Jul 1;104(7):2925-2930 |
1 | J:309359 Brinkmeier ML, Bando H, Camarano AC, Fujio S, Yoshimoto K, de Souza FS, Camper SA, Rathke's cleft-like cysts arise from Isl1 deletion in murine pituitary progenitors. J Clin Invest. 2020 Aug 3;130(8):4501-4515 |
1* | J:73085 Dasen JS, Barbera JP, Herman TS, Connell SO, Olson L, Ju B, Tollkuhn J, Baek SH, Rose DW, Rosenfeld MG, Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis. Genes Dev. 2001 Dec 1;15(23):3193-207 |
1 | J:70561 Dasen JS, O'Connell SM, Flynn SE, Treier M, Gleiberman AS, Szeto DP, Hooshmand F, Aggarwal AK, Rosenfeld MG, Reciprocal interactions of Pit1 and GATA2 mediate signaling gradient-induced determination of pituitary cell types. Cell. 1999 May 28;97(5):587-98 |
1 | J:235668 Goldsmith S, Lovell-Badge R, Rizzoti K, SOX2 is sequentially required for progenitor proliferation and lineage specification in the developing pituitary. Development. 2016 Jul 1;143(13):2376-88 |
1* | J:143548 Himes AD, Raetzman LT, Premature differentiation and aberrant movement of pituitary cells lacking both Hes1 and Prop1. Dev Biol. 2009 Jan 1;325(1):151-61 |
1* | J:19457 Japon MA, Rubinstein M, Low MJ, In situ hybridization analysis of anterior pituitary hormone gene expression during fetal mouse development. J Histochem Cytochem. 1994 Aug;42(8):1117-25 |
1 | J:240480 Kapali J, Kabat BE, Schmidt KL, Stallings CE, Tippy M, Jung DO, Edwards BS, Nantie LB, Raeztman LT, Navratil AM, Ellsworth BS, Foxo1 Is Required for Normal Somatotrope Differentiation. Endocrinology. 2016 Nov;157(11):4351-4363 |
1 | J:89087 Lamolet B, Poulin G, Chu K, Guillemot F, Tsai MJ, Drouin J, Tpit-independent function of NeuroD1(BETA2) in pituitary corticotroph differentiation. Mol Endocrinol. 2004 Apr;18(4):995-1003 |
1 | J:17223 Lin SC, Li S, Drolet DW, Rosenfeld MG, Pituitary ontogeny of the Snell dwarf mouse reveals Pit-1-independent and Pit-1-dependent origins of the thyrotrope. Development. 1994 Mar;120(3):515-22 |
1 | J:114149 Pope C, McNeilly JR, Coutts S, Millar M, Anderson RA, McNeilly AS, Gonadotrope and thyrotrope development in the human and mouse anterior pituitary gland. Dev Biol. 2006 Sep 1;297(1):172-81 |
1* | J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20 |
1* | J:33050 Sheng HZ, Zhadanov AB, Mosinger B Jr, Fujii T, Bertuzzi S, Grinberg A, Lee EJ, Huang SP, Mahon KA, Westphal H, Specification of pituitary cell lineages by the LIM homeobox gene Lhx3. Science. 1996 May 17;272(5264):1004-7 |
1 | J:108374 Vesper AH, Raetzman LT, Camper SA, Role of prophet of Pit1 (PROP1) in gonadotrope differentiation and puberty. Endocrinology. 2006 Apr;147(4):1654-63 |
1 | J:112960 Zhu X, Zhang J, Tollkuhn J, Ohsawa R, Bresnick EH, Guillemot F, Kageyama R, Rosenfeld MG, Sustained Notch signaling in progenitors is required for sequential emergence of distinct cell lineages during organogenesis. Genes Dev. 2006 Oct 1;20(19):2739-53 |
Tshz1 teashirt zinc finger family member 1 (Synonyms: 5730407I04Rik, D18Bwg1409e, Mtsh1, NY-CO-33, Sdccag33, teashirt1, Tsh1) | |
Results | Reference |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
2 | J:256526 Kuerbitz J, Arnett M, Ehrman S, Williams MT, Vorhees CV, Fisher SE, Garratt AN, Muglia LJ, Waclaw RR, Campbell K, Loss of Intercalated Cells (ITCs) in the Mouse Amygdala of Tshz1 Mutants Correlates with Fear, Depression, and Social Interaction Phenotypes. J Neurosci. 2018 Jan 31;38(5):1160-1177 |
1 | J:264268 Li J, Wang C, Zhang Z, Wen Y, An L, Liang Q, Xu Z, Wei S, Li W, Guo T, Liu G, Tao G, You Y, Du H, Fu Z, He M, Chen B, Campbell K, Alvarez-Buylla A, Rubenstein JL, Yang Z, Transcription Factors Sp8 and Sp9 Coordinately Regulate Olfactory Bulb Interneuron Development. Cereb Cortex. 2018 Sep 1;28(9):3278-3294 |
1* | J:246476 Raum JC, Soleimanpour SA, Groff DN, Core N, Fasano L, Garratt AN, Dai C, Powers AC, Stoffers DA, Tshz1 Regulates Pancreatic beta-Cell Maturation. Diabetes. 2015 Aug;64(8):2905-14 |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
Tshz3 teashirt zinc finger family member 3 (Synonyms: A630038G13Rik, teashirt3, Tsh3, Zfp537) | |
Results | Reference |
1 | J:360377 Kesdiren E, Martens H, Brand F, Werfel L, Wedekind L, Trowe MO, Schmitz J, Hennies I, Geffers R, Gucev Z, Seeman T, Schmidt S, Tasic V, Fasano L, Brasen JH, Kispert A, Christians A, Haffner D, Weber RG, Heterozygous variants in the teashirt zinc finger homeobox 3 (TSHZ3) gene in human congenital anomalies of the kidney and urinary tract. Eur J Hum Genet. 2024 Oct 17; |
1 | J:202129 Martin E, Caubit X, Airik R, Vola C, Fatmi A, Kispert A, Fasano L, TSHZ3 and SOX9 regulate the timing of smooth muscle cell differentiation in the ureter by reducing myocardin activity. PLoS One. 2013;8(5):e63721 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26 |
1 | J:159315 Xie Z, Ma X, Ji W, Zhou G, Lu Y, Xiang Z, Wang YX, Zhang L, Hu Y, Ding YQ, Zhang WJ, Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6510-5 |
Tsku tsukushi, small leucine rich proteoglycan (Synonyms: 9530051K01Rik, Lrrc54) | |
Results | Reference |
1 | J:193105 Hossain M, Ahmed G, Naser IB, Shinmyo Y, Ito A, Riyadh MA, Felemban A, Song X, Ohta K, Tanaka H, The combinatorial guidance activities of draxin and Tsukushi are essential for forebrain commissure formation. Dev Biol. 2013 Feb 1;374(1):58-70 |
Tspan2 tetraspanin 2 (Synonyms: 6330415F13Rik, B230119D02Rik) | |
Results | Reference |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
Tspan5 tetraspanin 5 (Synonyms: 2810455A09Rik, 4930505M03Rik, NET-4, Tm4sf9) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Tspan7 tetraspanin 7 (Synonyms: 1200014P11Rik, A15, Cd231, PE31, TALLA, Tm4sf2) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Tspan13 tetraspanin 13 (Synonyms: 1100001I23Rik, Tm4sf13) | |
Results | Reference |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Tspan32 tetraspanin 32 (Synonyms: Art-1, D7Wsu37e, Phemx, Tspan32, Tssc6) | |
Results | Reference |
1* | J:63702 Paulsen M, El-Maarri O, Engemann S, Strodicke M, Franck O, Davies K, Reinhardt R, Reik W, Walter J, Sequence conservation and variability of imprinting in the beckwith-wiedemann syndrome gene cluster in human and mouse. Hum Mol Genet. 2000 Jul 22;9(12):1829-41 |
1 | J:101003 Robb L, Tarrant J, Groom J, Ibrahim M, Li R, Borobakas B, Wright MD, Molecular characterisation of mouse and human TSSC6: evidence that TSSC6 is a genuine member of the tetraspanin superfamily and is expressed specifically in haematopoietic organs. Biochim Biophys Acta. 2001 Nov 11;1522(1):31-41 |
Tspyl2 TSPY-like 2 (Synonyms: CINAP, DENTT, DXBwg1396e, DXHXS1008E, E130307F10Rik) | |
Results | Reference |
4* | J:82210 Ozbun LL, Martinez A, Angdisen J, Umphress S, Kang Y, Wang M, You M, Jakowlew SB, Differentially expressed nucleolar TGF-beta1 target (DENTT) in mouse development. Dev Dyn. 2003 Mar;226(3):491-511 |
Tsr3 TSR3 20S rRNA accumulation (Synonyms: 0610007P22Rik, 1110014B11Rik) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Tssc4 tumor-suppressing subchromosomal transferable fragment 4 (Synonyms: ESTM671070) | |
Results | Reference |
1* | J:63702 Paulsen M, El-Maarri O, Engemann S, Strodicke M, Franck O, Davies K, Reinhardt R, Reik W, Walter J, Sequence conservation and variability of imprinting in the beckwith-wiedemann syndrome gene cluster in human and mouse. Hum Mol Genet. 2000 Jul 22;9(12):1829-41 |
Tst thiosulfate sulfurtransferase, mitochondrial (Synonyms: Rhodanese) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Ttc36 tetratricopeptide repeat domain 36 (Synonyms: MGC:25970, MGC:37247, MGC:37838) | |
Results | Reference |
1* | J:237208 Zhou Y, He Q, Chen J, Liu Y, Mao Z, Lyu Z, Ni D, Long Y, Ju P, Liu J, Gu Y, Zhou Q, The expression patterns of Tetratricopeptide repeat domain 36 (Ttc36). Gene Expr Patterns. 2016 Nov;22(2):37-45 |
Ttn titin (Synonyms: 1100001C23Rik, 2310036G12Rik, 2310057K23Rik, 2310074I15Rik, connectin, D330041I19Rik, D830007G01Rik, L56, mdm, shru) | |
Results | Reference |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
1* | J:59885 Fougerousse F, Bullen P, Herasse M, Lindsay S, Richard I, Wilson D, Suel L, Durand M, Robson S, Abitbol M, Beckmann JS, Strachan T, Human-mouse differences in the embryonic expression patterns of developmental control genes and disease genes. Hum Mol Genet. 2000 Jan 22;9(2):165-73 |
1 | J:104324 Hirschy A, Schatzmann F, Ehler E, Perriard JC, Establishment of cardiac cytoarchitecture in the developing mouse heart. Dev Biol. 2006 Jan 15;289(2):430-41 |
Ttr transthyretin (Synonyms: prealbumin) | |
Results | Reference |
1 | J:289341 Filatova A, Rey LK, Lechler MB, Schaper J, Hempel M, Posmyk R, Szczaluba K, Santen GWE, Wieczorek D, Nuber UA, Mutations in SMARCB1 and in other Coffin-Siris syndrome genes lead to various brain midline defects. Nat Commun. 2019 Jul 4;10(1):2966 |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
2 | J:173543 Harper J, Mould A, Andrews RM, Bikoff EK, Robertson EJ, The transcriptional repressor Blimp1/Prdm1 regulates postnatal reprogramming of intestinal enterocytes. Proc Natl Acad Sci U S A. 2011 Jun 28;108(26):10585-90 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:64091 Louvi A, Wassef M, Ectopic engrailed 1 expression in the dorsal midline causes cell death, abnormal differentiation of circumventricular organs and errors in axonal pathfinding. Development. 2000 Sep;127(18):4061-71 |
1* | J:221341 Lun MP, Johnson MB, Broadbelt KG, Watanabe M, Kang YJ, Chau KF, Springel MW, Malesz A, Sousa AM, Pletikos M, Adelita T, Calicchio ML, Zhang Y, Holtzman MJ, Lidov HG, Sestan N, Steen H, Monuki ES, Lehtinen MK, Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production. J Neurosci. 2015 Mar 25;35(12):4903-16 |
2 | J:320719 Parichha A, Suresh V, Chatterjee M, Kshirsagar A, Ben-Reuven L, Olender T, Taketo MM, Radosevic V, Bobic-Rasonja M, Trnski S, Holtzman MJ, Jovanov-Milosevic N, Reiner O, Tole S, Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate. Nat Commun. 2022 Feb 2;13(1):633 |
1* | J:105760 Swetloff A, Ferretti P, Changes in E2F5 intracellular localization in mouse and human choroid plexus epithelium with development. Int J Dev Biol. 2005;49(7):859-65 |
Ttyh1 tweety family member 1 (Synonyms: 4930459B04Rik, 6330408P11Rik, tty) | |
Results | Reference |
1* | J:161796 Kumada T, Yamanaka Y, Kitano A, Shibata M, Awaya T, Kato T, Okawa K, Abe T, Oshima N, Nakahata T, Heike T, Ttyh1, a Ca(2+)-binding protein localized to the endoplasmic reticulum, is required for early embryonic development. Dev Dyn. 2010 Aug;239(8):2233-45 |
Ttyh2 tweety family member 2 (Synonyms: 1110001A03Rik) | |
Results | Reference |
1* | J:258542 Hupe M, Li MX, Kneitz S, Davydova D, Yokota C, Kele-Olovsson J, Hot B, Stenman JM, Gessler M, Gene expression profiles of brain endothelial cells during embryonic development at bulk and single-cell levels. Sci Signal. 2017 Jul 11;10(487) |
Tub TUB bipartite transcription factor (Synonyms: rd5, tub) | |
Results | Reference |
1* | J:49663 Sahly I, Gogat K, Kobetz A, Marchant D, Menasche M, Castel M , Revah F , Dufier J , Guerre-Millo M , Abitbol MM, Prominent neuronal-specific tub gene expression in cellular targets of tubby mice mutation. Hum Mol Genet. 1998 Sep;7(9):1437-47 |
Tuba1a tubulin, alpha 1A (Synonyms: Talpha1 alpha-tubulin, Tuba-1, Tuba1) | |
Results | Reference |
1* | J:169198 Braun A, Breuss M, Salzer MC, Flint J, Cowan NJ, Keays DA, Tuba8 is expressed at low levels in the developing mouse and human brain. Am J Hum Genet. 2010 May 14;86(5):819-22; author reply 822-3 |
1 | J:332919 Leca I, Phillips AW, Ushakova L, Cushion TD, Keays DA, Codon modification of Tuba1a alters mRNA levels and causes a severe neurodevelopmental phenotype in mice. Sci Rep. 2023 Jan 21;13(1):1215 |
1 | J:330439 Liu H, He L, Cheng Q, Luo W, Zhao T, Yang D, Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states. Int J Mol Med. 2022 Nov;50(5) |
1 | J:316972 Mehta A, Dobersch S, Dammann RH, Bellusci S, Ilinskaya ON, Braun T, Barreto G, Validation of Tuba1a as appropriate internal control for normalization of gene expression analysis during mouse lung development. Int J Mol Sci. 2015 Feb 25;16(3):4492-511 |
1* | J:124438 Poirier K, Keays DA, Francis F, Saillour Y, Bahi N, Manouvrier S, Fallet-Bianco C, Pasquier L, Toutain A, Tuy FP, Bienvenu T, Joriot S, Odent S, Ville D, Desguerre I, Goldenberg A, Moutard ML, Fryns JP, van Esch H, Harvey RJ, Siebold C, Flint J, BeldjordC, Chelly J, Large spectrum of lissencephaly and pachygyria phenotypes resulting from de novo missense mutations in tubulin alpha 1A (TUBA1A). Hum Mutat. 2007 Nov;28(11):1055-64 |
Tuba1b tubulin, alpha 1B (Synonyms: Tuba2) | |
Results | Reference |
1 | J:332919 Leca I, Phillips AW, Ushakova L, Cushion TD, Keays DA, Codon modification of Tuba1a alters mRNA levels and causes a severe neurodevelopmental phenotype in mice. Sci Rep. 2023 Jan 21;13(1):1215 |
2 | J:330439 Liu H, He L, Cheng Q, Luo W, Zhao T, Yang D, Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states. Int J Mol Med. 2022 Nov;50(5) |
Tuba1c tubulin, alpha 1C (Synonyms: M[a]6, Tuba6) | |
Results | Reference |
1 | J:332919 Leca I, Phillips AW, Ushakova L, Cushion TD, Keays DA, Codon modification of Tuba1a alters mRNA levels and causes a severe neurodevelopmental phenotype in mice. Sci Rep. 2023 Jan 21;13(1):1215 |
Tuba4a tubulin, alpha 4A (Synonyms: M[a]4, Tuba4) | |
Results | Reference |
1 | J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6 |
2 | J:28082 Holmberg M, Leonardsson G, Ny T, The species-specific differences in the cAMP regulation of the tissue-type plasminogen activator gene between rat, mouse and human is caused by a one-nucleotide substitution in the cAMP-responsive element of the promoters. Eur J Biochem. 1995 Jul 15;231(2):466-74 |
1 | J:332919 Leca I, Phillips AW, Ushakova L, Cushion TD, Keays DA, Codon modification of Tuba1a alters mRNA levels and causes a severe neurodevelopmental phenotype in mice. Sci Rep. 2023 Jan 21;13(1):1215 |
2* | J:280280 Rutledge EA, Parvez RK, Short KM, Smyth IM, McMahon AP, Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease. Dev Biol. 2019 Oct 15;454(2):156-169 |
Tuba8 tubulin, alpha 8 | |
Results | Reference |
2* | J:169198 Braun A, Breuss M, Salzer MC, Flint J, Cowan NJ, Keays DA, Tuba8 is expressed at low levels in the developing mouse and human brain. Am J Hum Genet. 2010 May 14;86(5):819-22; author reply 822-3 |
Tubb1 tubulin, beta 1 class VI (Synonyms: 2810484G07Rik) | |
Results | Reference |
1* | J:196330 Breuss M, Heng JI, Poirier K, Tian G, Jaglin XH, Qu Z, Braun A, Gstrein T, Ngo L, Haas M, Bahi-Buisson N, Moutard ML, Passemard S, Verloes A, Gressens P, Xie Y, Robson KJ, Rani DS, Thangaraj K, Clausen T, Chelly J, Cowan NJ, Keays DA, Mutations in the beta-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities. Cell Rep. 2012 Dec 27;2(6):1554-62 |
Tubb2a tubulin, beta 2A class IIA | |
Results | Reference |
1* | J:196330 Breuss M, Heng JI, Poirier K, Tian G, Jaglin XH, Qu Z, Braun A, Gstrein T, Ngo L, Haas M, Bahi-Buisson N, Moutard ML, Passemard S, Verloes A, Gressens P, Xie Y, Robson KJ, Rani DS, Thangaraj K, Clausen T, Chelly J, Cowan NJ, Keays DA, Mutations in the beta-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities. Cell Rep. 2012 Dec 27;2(6):1554-62 |
Tubb2b tubulin, beta 2B class IIB (Synonyms: 2410129E14Rik, brdp) | |
Results | Reference |
1* | J:169198 Braun A, Breuss M, Salzer MC, Flint J, Cowan NJ, Keays DA, Tuba8 is expressed at low levels in the developing mouse and human brain. Am J Hum Genet. 2010 May 14;86(5):819-22; author reply 822-3 |
1* | J:196330 Breuss M, Heng JI, Poirier K, Tian G, Jaglin XH, Qu Z, Braun A, Gstrein T, Ngo L, Haas M, Bahi-Buisson N, Moutard ML, Passemard S, Verloes A, Gressens P, Xie Y, Robson KJ, Rani DS, Thangaraj K, Clausen T, Chelly J, Cowan NJ, Keays DA, Mutations in the beta-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities. Cell Rep. 2012 Dec 27;2(6):1554-62 |
1* | J:227088 Breuss M, Morandell J, Nimpf S, Gstrein T, Lauwers M, Hochstoeger T, Braun A, Chan K, Sanchez Guajardo ER, Zhang L, Suplata M, Heinze KG, Elsayad K, Keays DA, The Expression of Tubb2b Undergoes a Developmental Transition in Murine Cortical Neurons. J Comp Neurol. 2015 Oct 15;523(15):2161-86 |
1* | J:130714 Tachikawa K, Sasaki S, Maeda T, Nakajima K, Identification of molecules preferentially expressed beneath the marginal zone in the developing cerebral cortex. Neurosci Res. 2008 Feb;60(2):135-46 |
Tubb3 tubulin, beta 3 class III (Synonyms: 3200002H15Rik, betaIII-tubulin, Tuj1) | |
Results | Reference |
1 | J:333560 Ahmed NY, Knowles R, Liu L, Yan Y, Li X, Schumann U, Wang Y, Sontani Y, Reynolds N, Natoli R, Wen J, Del Pino I, Mi D, Dehorter N, Developmental deficits of MGE-derived interneurons in the Cntnap2 knockout mouse model of autism spectrum disorder. Front Cell Dev Biol. 2023;11:1112062 |
1* | J:66790 Anderson SA, Marin O, Horn C, Jennings K, Rubenstein JL, Distinct cortical migrations from the medial and lateral ganglionic eminences. Development. 2001 Feb;128(3):353-63 |
2 | J:181188 Aoki H, Hara A, Era T, Kunisada T, Yamada Y, Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis. Development. 2012 Feb;139(4):667-77 |
1 | J:109820 Arnaud L, Ballif BA, Forster E, Cooper JA, Fyn tyrosine kinase is a critical regulator of disabled-1 during brain development. Curr Biol. 2003 Jan 8;13(1):9-17 |
1* | J:199435 Barraud P, St John JA, Stolt CC, Wegner M, Baker CV, Olfactory ensheathing glia are required for embryonic olfactory axon targeting and the migration of gonadotropin-releasing hormone neurons. Biol Open. 2013 Jul 15;2(7):750-9 |
1 | J:284524 Bendriem RM, Singh S, Aleem AA, Antonetti DA, Ross ME, Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex. Elife. 2019 Dec 3;8:e49376 |
1 | J:305458 Bertacchi M, Romano AL, Loubat A, Tran Mau-Them F, Willems M, Faivre L, Khau van Kien P, Perrin L, Devillard F, Sorlin A, Kuentz P, Philippe C, Garde A, Neri F, Di Giaimo R, Oliviero S, Cappello S, D'Incerti L, Frassoni C, Studer M, NR2F1 regulates regional progenitor dynamics in the mouse neocortex and cortical gyrification in BBSOAS patients. EMBO J. 2020 Jul 1;39(13):e104163 |
1 | J:356256 Bertino F, Mukherjee D, Bonora M, Bagowski C, Nardelli J, Metani L, Zanin Venturini DI, Chianese D, Santander N, Salaroglio IC, Hentschel A, Quarta E, Genova T, McKinney AA, Allocco AL, Fiorito V, Petrillo S, Ammirata G, De Giorgio F, Dennis E, Allington G, Maier F, Shoukier M, Gloning KP, Munaron L, Mussano F, Salsano E, Pareyson D, di Rocco M, Altruda F, Panagiotakos G, Kahle KT, Gressens P, Riganti C, Pinton PP, Roos A, Arnold T, Tolosano E, Chiabrando D, Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus. Cell Rep Med. 2024 Jul 16;5(7):101647 |
1 | J:278765 Bittermann E, Abdelhamed Z, Liegel RP, Menke C, Timms A, Beier DR, Stottmann RW, Differential requirements of tubulin genes in mammalian forebrain development. PLoS Genet. 2019 Aug;15(8):e1008243 |
1 | J:277168 Bohuslavova R, Cerychova R, Papousek F, Olejnickova V, Bartos M, Gorlach A, Kolar F, Sedmera D, Semenza GL, Pavlinkova G, HIF-1alpha is required for development of the sympathetic nervous system. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13414-13423 |
1 | J:147315 Boisseau S, Kunert-Keil C, Lucke S, Bouron A, Heterogeneous distribution of TRPC proteins in the embryonic cortex. Histochem Cell Biol. 2009 Mar;131(3):355-63 |
1 | J:287985 Bosze B, Moon MS, Kageyama R, Brown NL, Simultaneous Requirements for Hes1 in Retinal Neurogenesis and Optic Cup-Stalk Boundary Maintenance. J Neurosci. 2020 Feb 12;40(7):1501-1513 |
1* | J:169198 Braun A, Breuss M, Salzer MC, Flint J, Cowan NJ, Keays DA, Tuba8 is expressed at low levels in the developing mouse and human brain. Am J Hum Genet. 2010 May 14;86(5):819-22; author reply 822-3 |
1* | J:196330 Breuss M, Heng JI, Poirier K, Tian G, Jaglin XH, Qu Z, Braun A, Gstrein T, Ngo L, Haas M, Bahi-Buisson N, Moutard ML, Passemard S, Verloes A, Gressens P, Xie Y, Robson KJ, Rani DS, Thangaraj K, Clausen T, Chelly J, Cowan NJ, Keays DA, Mutations in the beta-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities. Cell Rep. 2012 Dec 27;2(6):1554-62 |
1 | J:68904 Brouns MR, Matheson SF, Settleman J, p190 RhoGAP is the principal Src substrate in brain and regulates axon outgrowth, guidance and fasciculation. Nat Cell Biol. 2001 Apr;3(4):361-7 |
1 | J:316183 Cai Y, Yoneda M, Tomita T, Kurotani R, Okamoto M, Kido T, Abe H, Mitzner W, Guha A, Kimura S, Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice. BMC Pulm Med. 2015 Jul 16;15:72 |
1 | J:171024 Calmont A, Thapar N, Scambler PJ, Burns AJ, Absence of the vagus nerve in the stomach of Tbx1-/- mutant mice. Neurogastroenterol Motil. 2011 Feb;23(2):125-30 |
1 | J:112971 Camarero G, Tyrsin OY, Xiang C, Pfeiffer V, Pleiser S, Wiese S, Gotz R, Rapp UR, Cortical migration defects in mice expressing A-RAF from the B-RAF locus. Mol Cell Biol. 2006 Oct;26(19):7103-15 |
1 | J:282102 Canizares MA, Albors AR, Singer G, Suttie N, Gorkic M, Felts P, Storey KG, Multiple steps characterise ventricular layer attrition to form the ependymal cell lining of the adult mouse spinal cord central canal. J Anat. 2019 Oct 31; |
1 | J:332313 Cantu-Guerra HL, Papazian MR, Gorsky AL, Alekos NS, Caccavano A, Karagulyan N, Neef J, Vicini S, Moser T, Coate TM, Cochlear hair cell innervation is dependent on a modulatory function of Semaphorin-3A. Dev Dyn. 2023 Jan;252(1):124-144 |
1 | J:228026 Capecchi MR, Pozner A, ASPM regulates symmetric stem cell division by tuning Cyclin E ubiquitination. Nat Commun. 2015;6:8763 |
1 | J:182669 Cappello S, Bohringer CR, Bergami M, Conzelmann KK, Ghanem A, Tomassy GS, Arlotta P, Mainardi M, Allegra M, Caleo M, van Hengel J, Brakebusch C, Gotz M, A radial glia-specific role of RhoA in double cortex formation. Neuron. 2012 Mar 8;73(5):911-24 |
1 | J:264379 Cardenas A, Villalba A, de Juan Romero C, Pico E, Kyrousi C, Tzika AC, Tessier-Lavigne M, Ma L, Drukker M, Cappello S, Borrell V, Evolution of Cortical Neurogenesis in Amniotes Controlled by Robo Signaling Levels. Cell. 2018 Jul 26;174(3):590-606.e21 |
1 | J:300487 Chai G, Webb A, Li C, Antaki D, Lee S, Breuss MW, Lang N, Stanley V, Anzenberg P, Yang X, Marshall T, Gaffney P, Wierenga KJ, Chung BH, Tsang MH, Pais LS, Lovgren AK, VanNoy GE, Rehm HL, Mirzaa G, Leon E, Diaz J, Neumann A, Kalverda AP, Manfield IW, Parry DA, Logan CV, Johnson CA, Bonthron DT, Valleley EMA, Issa MY, Abdel-Ghafar SF, Abdel-Hamid MS, Jennings P, Zaki MS, Sheridan E, Gleeson JG, Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021 Jan 20;109(2):241-256.e9 |
1* | J:316608 Chen C, Zhou Z, Zhong M, Zhang Y, Li M, Zhang L, Qu M, Yang J, Wang Y, Yu Z, Thyroid hormone promotes neuronal differentiation of embryonic neural stem cells by inhibiting STAT3 signaling through TRalpha1. Stem Cells Dev. 2012 Sep 20;21(14):2667-81 |
1 | J:241332 Chen HR, Juan HC, Wong YH, Tsai JW, Fann MJ, Cdk12 Regulates Neurogenesis and Late-Arising Neuronal Migration in the Developing Cerebral Cortex. Cereb Cortex. 2017 Mar 01;27(3):2289-2302 |
1 | J:183920 Chen J, Lai F, Niswander L, The ubiquitin ligase mLin41 temporally promotes neural progenitor cell maintenance through FGF signaling. Genes Dev. 2012 Apr 15;26(8):803-15 |
1* | J:143541 Chen L, Melendez J, Campbell K, Kuan CY, Zheng Y, Rac1 deficiency in the forebrain results in neural progenitor reduction and microcephaly. Dev Biol. 2009 Jan 1;325(1):162-70 |
1 | J:301138 Chen SH, Lu CH, Tsai MJ, TCTP is Essential for Cell Proliferation and Survival during CNS Development. Cells. 2020 Jan 6;9(1):133 |
1 | J:309738 Chevalier NR, Agbesi RJA, Ammouche Y, Dufour S, How Smooth Muscle Contractions Shape the Developing Enteric Nervous System. Front Cell Dev Biol. 2021;9:678975 |
1 | J:235552 Chinn GA, Hirokawa KE, Chuang TM, Urbina C, Patel F, Fong J, Funatsu N, Monuki ES, Agenesis of the Corpus Callosum Due to Defective Glial Wedge Formation in Lhx2 Mutant Mice. Cereb Cortex. 2015 Sep;25(9):2707-18 |
1 | J:102162 Cicero S, Herrup K, Cyclin-dependent kinase 5 is essential for neuronal cell cycle arrest and differentiation. J Neurosci. 2005 Oct 19;25(42):9658-68 |
1 | J:179898 Coate TM, Raft S, Zhao X, Ryan AK, Crenshaw EB 3rd, Kelley MW, Otic Mesenchyme Cells Regulate Spiral Ganglion Axon Fasciculation through a Pou3f4/EphA4 Signaling Pathway. Neuron. 2012 Jan 12;73(1):49-63 |
2 | J:226819 Coate TM, Spita NA, Zhang KD, Isgrig KT, Kelley MW, Neuropilin-2/Semaphorin-3F-mediated repulsion promotes inner hair cell innervation by spiral ganglion neurons. Elife. 2015;4 |
1* | J:332642 Cohen-Gulkar M, David A, Messika-Gold N, Eshel M, Ovadia S, Zuk-Bar N, Idelson M, Cohen-Tayar Y, Reubinoff B, Ziv T, Shamay M, Elkon R, Ashery-Padan R, The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration. PLoS Biol. 2023 Jan;21(1):e3001924 |
2 | J:257926 Collinson JM, Lindstrom NO, Neves C, Wallace K, Meharg C, Charles RH, Ross ZK, Fraser AM, Mbogo I, Oras K, Nakamoto M, Barker S, Duce S, Miedzybrodzka Z, Vargesson N, The developmental and genetic basis of 'clubfoot' in the peroneal muscular atrophy mutant mouse. Development. 2018 Feb 8;145(3):dev160093 |
1 | J:166770 Coppola E, d'Autreaux F, Rijli FM, Brunet JF, Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation. Development. 2010 Dec;137(24):4211-20 |
1* | J:326932 Dai SK, Liu PP, Li X, Jiao LF, Teng ZQ, Liu CM, Dynamic profiling and functional interpretation of histone lysine crotonylation and lactylation during neural development. Development. 2022 Jul 15;149(14):dev200049 |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
1 | J:205408 Delalande JM, Natarajan D, Vernay B, Finlay M, Ruhrberg C, Thapar N, Burns AJ, Vascularisation is not necessary for gut colonisation by enteric neural crest cells. Dev Biol. 2014 Jan 15;385(2):220-9 |
1* | J:139991 Ding X, Jin Y, Wu Y, Wu Y, Wu H, Xiong L, Song X, Liu S, Fan W, Fan M, Localization and cellular distribution of CPNE5 in embryonic mouse brain. Brain Res. 2008 Aug 11;1224:20-8 |
1 | J:347764 Dupraz S, Hilton BJ, Husch A, Santos TE, Coles CH, Stern S, Brakebusch C, Bradke F, RhoA Controls Axon Extension Independent of Specification in the Developing Brain. Curr Biol. 2019 Nov 18;29(22):3874-3886.e9 |
1 | J:104125 Evans AL, Gage PJ, Expression of the homeobox gene Pitx2 in neural crest is required for optic stalk and ocular anterior segment development. Hum Mol Genet. 2005 Nov 15;14(22):3347-59 |
1 | J:282828 Fan D, Chettouh Z, Consalez GG, Brunet JF, Taste bud formation depends on taste nerves. Elife. 2019 Oct 1;8:e49226 |
1 | J:139119 Fan X, Kim HJ, Bouton D, Warner M, Gustafsson JA, Expression of liver X receptor beta is essential for formation of superficial cortical layers and migration of later-born neurons. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13445-50 |
1 | J:144651 Farkas LM, Haffner C, Giger T, Khaitovich P, Nowick K, Birchmeier C, Paabo S, Huttner WB, Insulinoma-associated 1 has a panneurogenic role and promotes the generation and expansion of basal progenitors in the developing mouse neocortex. Neuron. 2008 Oct 9;60(1):40-55 |
1* | J:214972 Fei D, Huang T, Krimm RF, The neurotrophin receptor p75 regulates gustatory axon branching and promotes innervation of the tongue during development. Neural Dev. 2014;9:15 |
1 | J:211816 Fei JF, Haffner C, Huttner WB, 3' UTR-dependent, miR-92-mediated restriction of Tis21 expression maintains asymmetric neural stem cell division to ensure proper neocortex size. Cell Rep. 2014 Apr 24;7(2):398-411 |
1* | J:198483 Finelli MJ, Murphy KJ, Chen L, Zou H, Differential phosphorylation of Smad1 integrates BMP and neurotrophin pathways through Erk/Dusp in axon development. Cell Rep. 2013 May 30;3(5):1592-606 |
1* | J:360528 Fritzsch B, Weng X, Yamoah EN, Qin T, Hui CC, Lebron-Mora L, Pavlinkova G, Sham MH, Irx3/5 Null Deletion in Mice Blocks Cochlea-Saccule Segregation and Disrupts the Auditory Tonotopic Map. J Comp Neurol. 2024 Dec;532(12):e70008 |
1* | J:361965 Fujimoto T, Mori M, Tonosaki M, Yaoi T, Nakano K, Okamura T, Itoh K, Characterization of Dystrophin Dp71 Expression and Interaction Partners in Embryonic Brain Development: Implications for Duchenne/Becker Muscular Dystrophy. Mol Neurobiol. 2025 Jan 6; |
1 | J:206763 Gan Q, Lee A, Suzuki R, Yamagami T, Stokes A, Nguyen BC, Pleasure D, Wang J, Chen HW, Zhou CJ, Pax6 mediates ss-catenin signaling for self-renewal and neurogenesis by neocortical radial glial stem cells. Stem Cells. 2014 Jan;32(1):45-58 |
1 | J:233661 Garcia-Calero E, Botella-Lopez A, Bahamonde O, Perez-Balaguer A, Martinez S, FoxP2 protein levels regulate cell morphology changes and migration patterns in the vertebrate developing telencephalon. Brain Struct Funct. 2016 Jul;221(6):2905-17 |
1 | J:215584 Gil-Sanz C, Landeira B, Ramos C, Costa MR, Muller U, Proliferative defects and formation of a double cortex in mice lacking Mltt4 and Cdh2 in the dorsal telencephalon. J Neurosci. 2014 Aug 6;34(32):10475-87 |
1 | J:286645 Gilet JG, Ivanova EL, Trofimova D, Rudolf G, Meziane H, Broix L, Drouot N, Courraud J, Skory V, Voulleminot P, Osipenko M, Bahi-Buisson N, Yalcin B, Birling MC, Hinckelmann MV, Kwok BH, Allingham JS, Chelly J, Conditional switching of KIF2A mutation provides new insights into cortical malformation pathogeny. Hum Mol Genet. 2020 Mar 27;29(5):766-784 |
1* | J:243480 Gomez-Herreros F, Schuurs-Hoeijmakers JH, McCormack M, Greally MT, Rulten S, Romero-Granados R, Counihan TJ, Chaila E, Conroy J, Ennis S, Delanty N, Cortes-Ledesma F, de Brouwer AP, Cavalleri GL, El-Khamisy SF, de Vries BB, Caldecott KW, TDP2 protects transcription from abortive topoisomerase activity and is required for normal neural function. Nat Genet. 2014 May;46(5):516-21 |
1 | J:196579 Gonsalvez DG, Cane KN, Landman KA, Enomoto H, Young HM, Anderson CR, Proliferation and cell cycle dynamics in the developing stellate ganglion. J Neurosci. 2013 Apr 3;33(14):5969-79 |
1 | J:229100 Goto M, Hojo M, Ando M, Kita A, Kitagawa M, Ohtsuka T, Kageyama R, Miyamoto S, Hes1 and Hes5 are required for differentiation of pituicytes and formation of the neurohypophysis in pituitary development. Brain Res. 2015 Nov 2;1625:206-17 |
1 | J:180774 Grimsley-Myers CM, Sipe CW, Wu DK, Lu X, Redundant functions of Rac GTPases in inner ear morphogenesis. Dev Biol. 2012 Feb 15;362(2):172-86 |
1 | J:239666 Hagglund AC, Jones I, Carlsson L, A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development. Dis Model Mech. 2017 Mar 01;10(3):245-257 |
1 | J:133208 Hammerle B, Elizalde C, Tejedor FJ, The spatio-temporal and subcellular expression of the candidate Down syndrome gene Mnb/Dyrk1A in the developing mouse brain suggests distinct sequential roles in neuronal development. Eur J Neurosci. 2008 Mar;27(5):1061-74 |
1 | J:306265 Hao MM, Fung C, Boesmans W, Lowette K, Tack J, Vanden Berghe P, Development of the intrinsic innervation of the small bowel mucosa and villi. Am J Physiol Gastrointest Liver Physiol. 2020 Jan 1;318(1):G53-G65 |
1* | J:263979 Harley RJ, Murdy JP, Wang Z, Kelly MC, Ropp TF, Park SH, Maness PF, Manis PB, Coate TM, Neuronal cell adhesion molecule (NrCAM) is expressed by sensory cells in the cochlea and is necessary for proper cochlear innervation and sensory domain patterning during development. Dev Dyn. 2018 Mar 14; |
1* | J:137254 Harrison SJ, Parrish M, Monaghan AP, Sall3 is required for the terminal maturation of olfactory glomerular interneurons. J Comp Neurol. 2008 Apr 10;507(5):1780-94 |
1* | J:84752 Hartfuss E, Forster E, Bock HH, Hack MA, Leprince P, Luque JM, Herz J, Frotscher M, Gotz M, Reelin signaling directly affects radial glia morphology and biochemical maturation. Development. 2003 Oct;130(19):4597-609 |
1 | J:79021 Hebert JM, Mishina Y, McConnell SK, BMP signaling is required locally to pattern the dorsal telencephalic midline. Neuron. 2002 Sep 12;35(6):1029-41 |
1 | J:250521 Hecht JH, Siegenthaler JA, Patterson KP, Pleasure SJ, Primary cellular meningeal defects cause neocortical dysplasia and dyslamination. Ann Neurol. 2010 Oct;68(4):454-64 |
1* | J:253679 Hirst CS, Stamp LA, Bergner AJ, Hao MM, Tran MX, Morgan JM, Dutschmann M, Allen AM, Paxinos G, Furlong TM, McKeown SJ, Young HM, Kif1bp loss in mice leads to defects in the peripheral and central nervous system and perinatal death. Sci Rep. 2017 Nov 30;7(1):16676 |
1 | J:332402 Hockman D, Adameyko I, Kaucka M, Barraud P, Otani T, Hunt A, Hartwig AC, Sock E, Waithe D, Franck MCM, Ernfors P, Ehinger S, Howard MJ, Brown N, Reese J, Baker CVH, Striking parallels between carotid body glomus cell and adrenal chromaffin cell development. Dev Biol. 2018 Dec 1;444 Suppl 1(Suppl 1):S308-S324 |
1 | J:343095 Honeycutt SE, N'Guetta PY, Hardesty DM, Xiong Y, Cooper SL, Stevenson MJ, O'Brien LL, Netrin 1 directs vascular patterning and maturity in the developing kidney. Development. 2023 Nov 15;150(22) |
1 | J:276557 Hong GS, Lee SH, Lee B, Choi JH, Oh SJ, Jang Y, Hwang EM, Kim H, Jung J, Kim IB, Oh U, ANO1/TMEM16A regulates process maturation in radial glial cells in the developing brain. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12494-12499 |
1 | J:238096 Houlihan SL, Lanctot AA, Guo Y, Feng Y, Upregulation of neurovascular communication through filamin abrogation promotes ectopic periventricular neurogenesis. Elife. 2016 Sep 24;5:e17823 |
1 | J:173761 Hu ZL, Shi M, Huang Y, Zheng MH, Pei Z, Chen JY, Han H, Ding YQ, The role of the transcription factor Rbpj in the development of dorsal root ganglia. Neural Dev. 2011;6:14 |
1* | J:171479 Hutton SR, Pevny LH, SOX2 expression levels distinguish between neural progenitor populations of the developing dorsal telencephalon. Dev Biol. 2011 Apr 1;352(1):40-7 |
1* | J:137733 Iguchi T, Sakata K, Yoshizaki K, Tago K, Mizuno N, Itoh H, Orphan G protein-coupled receptor GPR56 regulates neural progenitor cell migration via a G alpha 12/13 and Rho pathway. J Biol Chem. 2008 May 23;283(21):14469-78 |
1 | J:122204 Imai F, Hirai S, Akimoto K, Koyama H, Miyata T, Ogawa M, Noguchi S, Sasaoka T, Noda T, Ohno S, Inactivation of aPKClambda results in the loss of adherens junctions in neuroepithelial cells without affecting neurogenesis in mouse neocortex. Development. 2006 May;133(9):1735-44 |
1 | J:217499 Iwashita M, Kataoka N, Toida K, Kosodo Y, Systematic profiling of spatiotemporal tissue and cellular stiffness in the developing brain. Development. 2014 Oct;141(19):3793-8 |
1 | J:334107 Jin Y, Gao X, Lu M, Chen G, Yang X, Ren N, Song Y, Hou C, Li J, Liu Q, Gao J, Loss of BAF (mSWI/SNF) chromatin-remodeling ATPase Brg1 causes multiple malformations of cortical development in mice. Hum Mol Genet. 2022 Oct 10;31(20):3504-3520 |
1 | J:279215 Jung JS, Zhang KD, Wang Z, McMurray M, Tkaczuk A, Ogawa Y, Hertzano R, Coate TM, Semaphorin-5B Controls Spiral Ganglion Neuron Branch Refinement during Development. J Neurosci. 2019 Aug 14;39(33):6425-6438 |
1 | J:170546 Kaltezioti V, Kouroupi G, Oikonomaki M, Mantouvalou E, Stergiopoulos A, Charonis A, Rohrer H, Matsas R, Politis PK, Prox1 regulates the notch1-mediated inhibition of neurogenesis. PLoS Biol. 2010;8(12):e1000565 |
1 | J:235517 Kam JW, Dumontier E, Baim C, Brignall AC, Mendes da Silva D, Cowan M, Kennedy TE, Cloutier JF, RGMB and neogenin control cell differentiation in the developing olfactory epithelium. Development. 2016 May 1;143(9):1534-46 |
1* | J:131010 Kameda Y, Ito M, Nishimaki T, Gotoh N, FRS2 alpha 2F/2F mice lack carotid body and exhibit abnormalities of the superior cervical sympathetic ganglion and carotid sinus nerve. Dev Biol. 2008 Feb 1;314(1):236-47 |
1* | J:77820 Kameda Y, Nishimaki T, Takeichi M, Chisaka O, Homeobox gene hoxa3 is essential for the formation of the carotid body in the mouse embryos. Dev Biol. 2002 Jul 1;247(1):197-209 |
1 | J:108229 Kappeler C, Saillour Y, Baudoin JP, Tuy FP, Alvarez C, Houbron C, Gaspar P, Hamard G, Chelly J, Metin C, Francis F, Branching and nucleokinesis defects in migrating interneurons derived from doublecortin knockout mice. Hum Mol Genet. 2006 May 1;15(9):1387-400 |
1 | J:126547 Ke Y, Zhang EE, Hagihara K, Wu D, Pang Y, Klein R, Curran T, Ranscht B, Feng GS, Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality. Mol Cell Biol. 2007 Oct;27(19):6706-17 |
2 | J:165476 Keimpema E, Barabas K, Morozov YM, Tortoriello G, Torii M, Cameron G, Yanagawa Y, Watanabe M, Mackie K, Harkany T, Differential subcellular recruitment of monoacylglycerol lipase generates spatial specificity of 2-arachidonoyl glycerol signaling during axonal pathfinding. J Neurosci. 2010 Oct 20;30(42):13992-4007 |
1 | J:197212 Kim HJ, Woo HM, Ryu J, Bok J, Kim JW, Choi SB, Park MH, Park HY, Koo SK, Conditional deletion of pten leads to defects in nerve innervation and neuronal survival in inner ear development. PLoS One. 2013;8(2):e55609 |
1* | J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347 |
1 | J:265096 Kim YJ, Ibrahim LA, Wang SZ, Yuan W, Evgrafov OV, Knowles JA, Wang K, Tao HW, Zhang LI, EphA7 regulates spiral ganglion innervation of cochlear hair cells. Dev Neurobiol. 2016 Apr;76(4):452-69 |
2 | J:251343 Kim YJ, Wang SZ, Tymanskyj S, Ma L, Tao HW, Zhang LI, Dcc Mediates Functional Assembly of Peripheral Auditory Circuits. Sci Rep. 2016 Apr 4;6:23799 |
1 | J:208421 Klimova L, Kozmik Z, Stage-dependent requirement of neuroretinal Pax6 for lens and retina development. Development. 2014 Mar;141(6):1292-302 |
1 | J:346372 Kolesova H, Hrabalova P, Bohuslavova R, Abaffy P, Fabriciova V, Sedmera D, Pavlinkova G, Reprogramming of the developing heart by Hif1a-deficient sympathetic system and maternal diabetes exposure. Front Endocrinol (Lausanne). 2024;15:1344074 |
1* | J:152410 Komai T, Iwanari H, Mochizuki Y, Hamakubo T, Shinkai Y, Expression of the mouse PR domain protein Prdm8 in the developing central nervous system. Gene Expr Patterns. 2009 Oct;9(7):503-14 |
1* | J:217303 Koudelka J, Horn JM, Vatanashevanopakorn C, Minichiello L, Genetic dissection of TrkB activated signalling pathways required for specific aspects of the taste system. Neural Dev. 2014;9:21 |
1 | J:195630 Krolewski RC, Packard A, Jang W, Wildner H, Schwob JE, Ascl1 (Mash1) knockout perturbs differentiation of nonneuronal cells in olfactory epithelium. PLoS One. 2012;7(12):e51737 |
1 | J:101055 Kuo G, Arnaud L, Kronstad-O'Brien P, Cooper JA, Absence of Fyn and Src causes a reeler-like phenotype. J Neurosci. 2005 Sep 14;25(37):8578-86 |
1 | J:159224 Kurosaka S, Leu NA, Zhang F, Bunte R, Saha S, Wang J, Guo C, He W, Kashina A, Arginylation-dependent neural crest cell migration is essential for mouse development. PLoS Genet. 2010;6(3):e1000878 |
1 | J:158681 Kuwahara A, Hirabayashi Y, Knoepfler PS, Taketo MM, Sakai J, Kodama T, Gotoh Y, Wnt signaling and its downstream target N-myc regulate basal progenitors in the developing neocortex. Development. 2010 Apr;137(7):1035-44 |
1* | J:127447 Kwiatkowski AV, Rubinson DA, Dent EW, Edward van Veen J, Leslie JD, Zhang J, Mebane LM, Philippar U, Pinheiro EM, Burds AA, Bronson RT, Mori S, Fassler R, Gertler FB, Ena/VASP Is Required for neuritogenesis in the developing cortex. Neuron. 2007 Nov 8;56(3):441-55 |
1 | J:254235 Lanctot AA, Guo Y, Le Y, Edens BM, Nowakowski RS, Feng Y, Loss of Brap Results in Premature G1/S Phase Transition and Impeded Neural Progenitor Differentiation. Cell Rep. 2017 Aug 1;20(5):1148-1160 |
1 | J:306218 Landin Malt A, Hogan AK, Smith CD, Madani MS, Lu X, Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling. J Cell Biol. 2020 Oct 5;219(10) |
1 | J:183370 Langsdorf A, Radzikinas K, Kroten A, Jain S, Ai X, Neural crest cell origin and signals for intrinsic neurogenesis in the mammalian respiratory tract. Am J Respir Cell Mol Biol. 2011 Mar;44(3):293-301 |
1* | J:143513 Lathia JD, Okun E, Tang SC, Griffioen K, Cheng A, Mughal MR, Laryea G, Selvaraj PK, ffrench-Constant C, Magnus T, Arumugam TV, Mattson MP, Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation. J Neurosci. 2008 Dec 17;28(51):13978-84 |
1 | J:178674 Lavado A, Oliver G, Six3 is required for ependymal cell maturation. Development. 2011 Dec;138(24):5291-300 |
1 | J:181920 Lee Y, Shull ER, Frappart PO, Katyal S, Enriquez-Rios V, Zhao J, Russell HR, Brown EJ, McKinnon PJ, ATR maintains select progenitors during nervous system development. EMBO J. 2012 Mar 7;31(5):1177-89 |
1 | J:146673 Leiper LJ, Ou J, Walczysko P, Kucerova R, Lavery DN, West JD, Collinson JM, Control of patterns of corneal innervation by Pax6. Invest Ophthalmol Vis Sci. 2009 Mar;50(3):1122-8 |
1 | J:87149 Li HS, Wang D, Shen Q, Schonemann MD, Gorski JA, Jones KR, Temple S, Jan LY, Jan YN, Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis. Neuron. 2003 Dec 18;40(6):1105-18 |
1* | J:294282 Li L, Ruan X, Wen C, Chen P, Liu W, Zhu L, Xiang P, Zhang X, Wei Q, Hou L, Yin B, Yuan J, Qiang B, Shu P, Peng X, The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019 Jul 16;28(3):698-711.e5 |
3 | J:301660 Li M, Lu G, Hu J, Shen X, Ju J, Gao Y, Qu L, Xia Y, Chen Y, Bai Y, EVA1A/TMEM166 Regulates Embryonic Neurogenesis by Autophagy. Stem Cell Reports. 2016 Mar 8;6(3):396-410 |
1 | J:136385 Li S, Jin Z, Koirala S, Bu L, Xu L, Hynes RO, Walsh CA, Corfas G, Piao X, GPR56 regulates pial basement membrane integrity and cortical lamination. J Neurosci. 2008 May 28;28(22):5817-26 |
1* | J:297829 Li W, Shen W, Zhang B, Tian K, Li Y, Mu L, Luo Z, Zhong X, Wu X, Liu Y, Zhou Y, Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b. Protein Cell. 2020 Mar;11(3):161-186 |
1 | J:285409 Li Y, Jiao J, Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia. Sci Adv. 2020 Jan;6(1):eaay6350 |
1 | J:106280 Li ZS, Schmauss C, Cuenca A, Ratcliffe E, Gershon MD, Physiological modulation of intestinal motility by enteric dopaminergic neurons and the D2 receptor: analysis of dopamine receptor expression, location, development, and function in wild-type and knock-out mice. J Neurosci. 2006 Mar 8;26(10):2798-807 |
1 | J:292113 Lin YN, Lee YS, Li SK, Tang TK, Loss of CPAP in developing mouse brain and its functional implication for human primary microcephaly. J Cell Sci. 2020 Jun 24;133(12):jcs243592 |
1* | J:170390 Lindstrom NO, Neves C, McIntosh R, Miedzybrodzka Z, Vargesson N, Martin Collinson J, Tissue specific characterisation of Lim-kinase 1 expression during mouse embryogenesis. Gene Expr Patterns. 2011 Mar-Apr;11(3-4):221-32 |
1 | J:188237 Liu W, Liu C, Zhu J, Shu P, Yin B, Gong Y, Qiang B, Yuan J, Peng X, MicroRNA-16 targets amyloid precursor protein to potentially modulate Alzheimer's-associated pathogenesis in SAMP8 mice. Neurobiol Aging. 2012 Mar;33(3):522-34 |
1 | J:322701 Liu Y, Chen Q, Jeong HW, Koh BI, Watson EC, Xu C, Stehling M, Zhou B, Adams RH, A specialized bone marrow microenvironment for fetal haematopoiesis. Nat Commun. 2022 Mar 14;13(1):1327 |
1 | J:160591 Liu Z, Owen T, Zhang L, Zuo J, Dynamic expression pattern of Sonic hedgehog in developing cochlear spiral ganglion neurons. Dev Dyn. 2010 Jun;239(6):1674-83 |
1 | J:288654 Lun MP, Shannon ML, Keles S, Reisli I, Luche N, Ryan D, Capuder K, Notarangelo LD, Lehtinen MK, Spatiotemporal Gradient of Cortical Neuron Death Contributes to Microcephaly in Knock-In Mouse Model of Ligase 4 Syndrome. Am J Pathol. 2019 Dec;189(12):2440-2449 |
1* | J:114661 Lyu YL, Lin CP, Azarova AM, Cai L, Wang JC, Liu LF, Role of topoisomerase IIbeta in the expression of developmentally regulated genes. Mol Cell Biol. 2006 Nov;26(21):7929-41 |
1* | J:333071 Ma H, Su L, Xia W, Wang W, Tan G, Jiao J, MacroH2A1.2 deficiency leads to neural stem cell differentiation defects and autism-like behaviors. EMBO Rep. 2021 Jul 5;22(7):e52150 |
1 | J:170677 Malagelada C, Lopez-Toledano MA, Willett RT, Jin ZH, Shelanski ML, Greene LA, RTP801/REDD1 regulates the timing of cortical neurogenesis and neuron migration. J Neurosci. 2011 Mar 2;31(9):3186-96 |
1 | J:160363 Mao J, Kim BM, Rajurkar M, Shivdasani RA, McMahon AP, Hedgehog signaling controls mesenchymal growth in the developing mammalian digestive tract. Development. 2010 May;137(10):1721-9 |
1 | J:316266 Martin-Ibanez R, Crespo E, Esgleas M, Urban N, Wang B, Waclaw R, Georgopoulos K, Martinez S, Campbell K, Vicario-Abejon C, Alberch J, Chan S, Kastner P, Rubenstein JL, Canals JM, Helios transcription factor expression depends on Gsx2 and Dlx1&2 function in developing striatal matrix neurons. Stem Cells Dev. 2012 Aug 10;21(12):2239-51 |
1 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
1 | J:187230 McKenna CC, Munjaal RP, Lwigale PY, Distinct roles for neuropilin1 and neuropilin2 during mouse corneal innervation. PLoS One. 2012;7(5):e37175 |
1 | J:330583 McKey J, Anbarci DN, Bunce C, Ontiveros AE, Behringer RR, Capel B, Integration of mouse ovary morphogenesis with developmental dynamics of the oviduct, ovarian ligaments, and rete ovarii. Elife. 2022 Sep 27;11:e81088 |
1 | J:273473 McKey J, Bunce C, Batchvarov IS, Ornitz DM, Capel B, Neural crest-derived neurons invade the ovary but not the testis during mouse gonad development. Proc Natl Acad Sci U S A. 2019 Mar 19;116(12):5570-5575 |
1 | J:284129 Meier S, Alfonsi F, Kurniawan ND, Milne MR, Kasherman MA, Delogu A, Piper M, Coulson EJ, The p75 neurotrophin receptor is required for the survival of neuronal progenitors and normal formation of the basal forebrain, striatum, thalamus and neocortex. Development. 2019 Sep 18;146(18):dev181933 |
1 | J:104532 Mendes SW, Henkemeyer M, Liebl DJ, Multiple Eph receptors and B-class ephrins regulate midline crossing of corpus callosum fibers in the developing mouse forebrain. J Neurosci. 2006 Jan 18;26(3):882-92 |
1 | J:144181 Meng H, Lee VM, Differential expression of sphingosine-1-phosphate receptors 1-5 in the developing nervous system. Dev Dyn. 2009 Feb;238(2):487-500 |
1 | J:198698 Meng L, Lin T, Peng G, Hsu JK, Lee S, Lin SY, Tsai RY, Nucleostemin deletion reveals an essential mechanism that maintains the genomic stability of stem and progenitor cells. Proc Natl Acad Sci U S A. 2013 Jul 9;110(28):11415-20 |
1* | J:264529 Miller SR, Benito C, Mirsky R, Jessen KR, Baker CVH, Neural crest Notch/Rbpj signaling regulates olfactory gliogenesis and neuronal migration. Genesis. 2018 Jun;56(6-7):e23215 |
1 | J:332403 Miller SR, Perera SN, Benito C, Stott SR, Baker CV, Evidence for a Notch1-mediated transition during olfactory ensheathing cell development. J Anat. 2016 Sep;229(3):369-83 |
1 | J:182762 Mundell NA, Plank JL, LeGrone AW, Frist AY, Zhu L, Shin MK, Southard-Smith EM, Labosky PA, Enteric nervous system specific deletion of Foxd3 disrupts glial cell differentiation and activates compensatory enteric progenitors. Dev Biol. 2012 Mar 15;363(2):373-87 |
1 | J:98698 Muzio L, Mallamaci A, Foxg1 confines Cajal-Retzius neuronogenesis and hippocampal morphogenesis to the dorsomedial pallium. J Neurosci. 2005 Apr 27;25(17):4435-41 |
2 | J:358157 N'Guetta PY, McLarnon SR, Tassou A, Geron M, Shirvan S, Hill RZ, Scherrer G, O'Brien LL, Comprehensive mapping of sensory and sympathetic innervation of the developing kidney. Cell Rep. 2024 Oct 22;43(10):114860 |
1 | J:194919 Nam J, Onitsuka I, Hatch J, Uchida Y, Ray S, Huang S, Li W, Zang H, Ruiz-Lozano P, Mukouyama YS, Coronary veins determine the pattern of sympathetic innervation in the developing heart. Development. 2013 Apr;140(7):1475-85 |
1* | J:201080 Nelson DA, Manhardt C, Kamath V, Sui Y, Santamaria-Pang A, Can A, Bello M, Corwin A, Dinn SR, Lazare M, Gervais EM, Sequeira SJ, Peters SB, Ginty F, Gerdes MJ, Larsen M, Quantitative single cell analysis of cell population dynamics during submandibular salivary gland development and differentiation. Biol Open. 2013 May 15;2(5):439-47 |
1 | J:295953 Niu X, Liu L, Wang T, Chuan X, Yu Q, Du M, Gu Y, Wang L, Mapping of Extrinsic Innervation of the Gastrointestinal Tract in the Mouse Embryo. J Neurosci. 2020 Aug 26;40(35):6691-6708 |
1 | J:181398 Ogata-Iwao M, Inatani M, Iwao K, Takihara Y, Nakaishi-Fukuchi Y, Irie F, Sato S, Furukawa T, Yamaguchi Y, Tanihara H, Heparan sulfate regulates intraretinal axon pathfinding by retinal ganglion cells. Invest Ophthalmol Vis Sci. 2011 Aug;52(9):6671-9 |
1 | J:282790 Ogawa Y, Sasanuma Y, Shitara S, Koshizuka A, Okada R, Sakuraba H, Oishi K, Abnormal organization during neurodevelopment in a mouse model of Sandhoff disease. Neurosci Res. 2019 Jul 21; |
1* | J:98297 Ohta Y, Itoh K, Yaoi T, Tando S, Fukui K, Fushiki S, Spatiotemporal patterns of expression of IGSF4 in developing mouse nervous system. Brain Res Dev Brain Res. 2005 Apr 21;156(1):23-31 |
1 | J:363605 Ortiz A, Ayhan F, Khandelwal N, Outland E, Jankovic M, Harper M, Konopka G, Cell-type-specific roles of FOXP1 in the excitatory neuronal lineage during early neocortical murine development. Cell Rep. 2025 Mar 5;44(3):115384 |
1 | J:187391 Pacal M, Bremner R, Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Dev Dyn. 2012 Oct;241(10):1525-44 |
1 | J:300967 Pajovic S, Siddaway R, Bridge T, Sheth J, Rakopoulos P, Kim B, Ryall S, Agnihotri S, Phillips L, Yu M, Li C, Milos S, Patel P, Srikanthan D, Huang A, Hawkins C, Epigenetic activation of a RAS/MYC axis in H3.3K27M-driven cancer. Nat Commun. 2020 Dec 4;11(1):6216 |
1 | J:320719 Parichha A, Suresh V, Chatterjee M, Kshirsagar A, Ben-Reuven L, Olender T, Taketo MM, Radosevic V, Bobic-Rasonja M, Trnski S, Holtzman MJ, Jovanov-Milosevic N, Reiner O, Tole S, Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate. Nat Commun. 2022 Feb 2;13(1):633 |
3 | J:246653 Park JC, Jeong WJ, Kim MY, Min D, Choi KY, Retinoic-acid-mediated HRas stabilization induces neuronal differentiation of neural stem cells during brain development. J Cell Sci. 2016 Aug 01;129(15):2997-3007 |
1 | J:160265 Patel AV, Krimm RF, BDNF is required for the survival of differentiated geniculate ganglion neurons. Dev Biol. 2010 Apr 15;340(2):419-29 |
1 | J:184933 Patel AV, Krimm RF, Neurotrophin-4 regulates the survival of gustatory neurons earlier in development using a different mechanism than brain-derived neurotrophic factor. Dev Biol. 2012 May 1;365(1):50-60 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1 | J:92098 Petersen PH, Zou K, Krauss S, Zhong W, Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis. Nat Neurosci. 2004 Aug;7(8):803-11 |
1 | J:326535 Petitpre C, Faure L, Uhl P, Fontanet P, Filova I, Pavlinkova G, Adameyko I, Hadjab S, Lallemend F, Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification. Nat Commun. 2022 Jul 5;13(1):3878 |
1 | J:154741 Prince JE, Cho JH, Dumontier E, Andrews W, Cutforth T, Tessier-Lavigne M, Parnavelas J, Cloutier JF, Robo-2 controls the segregation of a portion of basal vomeronasal sensory neuron axons to the posterior region of the accessory olfactory bulb. J Neurosci. 2009 Nov 11;29(45):14211-22 |
1 | J:155110 Puig I, Champeval D, De Santa Barbara P, Jaubert F, Lyonnet S, Larue L, Deletion of Pten in the mouse enteric nervous system induces ganglioneuromatosis and mimics intestinal pseudoobstruction. J Clin Invest. 2009 Dec;119(12):3586-96 |
1 | J:149563 Pulvers JN, Huttner WB, Brca1 is required for embryonic development of the mouse cerebral cortex to normal size by preventing apoptosis of early neural progenitors. Development. 2009 Jun;136(11):1859-68 |
2 | J:177268 Radzikinas K, Aven L, Jiang Z, Tran T, Paez-Cortez J, Boppidi K, Lu J, Fine A, Ai X, A Shh/miR-206/BDNF Cascade Coordinates Innervation and Formation of Airway Smooth Muscle. J Neurosci. 2011 Oct 26;31(43):15407-15 |
1 | J:208409 Reinert RB, Cai Q, Hong JY, Plank JL, Aamodt K, Prasad N, Aramandla R, Dai C, Levy SE, Pozzi A, Labosky PA, Wright CV, Brissova M, Powers AC, Vascular endothelial growth factor coordinates islet innervation via vascular scaffolding. Development. 2014 Apr;141(7):1480-91 |
1* | J:268254 Rich CA, Perera SN, Andratschke J, Stolt CC, Buehler DP, Southard-Smith EM, Wegner M, Britsch S, Baker CVH, Olfactory ensheathing cells abutting the embryonic olfactory bulb express Frzb, whose deletion disrupts olfactory axon targeting. Glia. 2018 Dec;66(12):2617-2631 |
1 | J:154061 Riesenberg AN, Liu Z, Kopan R, Brown NL, Rbpj cell autonomous regulation of retinal ganglion cell and cone photoreceptor fates in the mouse retina. J Neurosci. 2009 Oct 14;29(41):12865-77 |
1* | J:292351 Rodrigues DC, Harvey EM, Suraj R, Erickson SL, Mohammad L, Ren M, Liu H, He G, Kaplan DR, Ellis J, Yang G, Methylglyoxal couples metabolic and translational control of Notch signalling in mammalian neural stem cells. Nat Commun. 2020 Apr 24;11(1):2018 |
1* | J:325117 Romero DM, Poirier K, Belvindrah R, Moutkine I, Houllier A, LeMoing AG, Petit F, Boland A, Collins SC, Soiza-Reilly M, Yalcin B, Chelly J, Deleuze JF, Bahi-Buisson N, Francis F, Novel role of the synaptic scaffold protein Dlgap4 in ventricular surface integrity and neuronal migration during cortical development. Nat Commun. 2022 May 18;13(1):2746 |
1 | J:248731 Salehi P, Ge MX, Gundimeda U, Michelle Baum L, Lael Cantu H, Lavinsky J, Tao L, Myint A, Cruz C, Wang J, Nikolakopoulou AM, Abdala C, Kelley MW, Ohyama T, Coate TM, Friedman RA, Role of Neuropilin-1/Semaphorin-3A signaling in the functional and morphological integrity of the cochlea. PLoS Genet. 2017 Oct;13(10):e1007048 |
1 | J:311495 Salehi P, Myint A, Kim YJ, Ge MX, Lavinsky J, Ho MK, Crow AL, Cruz C, Monges-Hernadez M, Wang J, Hartiala J, Zhang LI, Allayee H, Lusis AJ, Ohyama T, Friedman RA, Genome-Wide Association Analysis Identifies Dcc as an Essential Factor in the Innervation of the Peripheral Vestibular System in Inbred Mice. J Assoc Res Otolaryngol. 2016 Oct;17(5):417-31 |
1 | J:277160 Sherrill HE, Jean P, Driver EC, Sanders TR, Fitzgerald TS, Moser T, Kelley MW, Pou4f1 Defines a Subgroup of Type I Spiral Ganglion Neurons and Is Necessary for Normal Inner Hair Cell Presynaptic Ca(2+) Signaling. J Neurosci. 2019 Jul 3;39(27):5284-5298 |
1 | J:213479 Shibasaki T, Tokunaga A, Sakamoto R, Sagara H, Noguchi S, Sasaoka T, Yoshida N, PTB deficiency causes the loss of adherens junctions in the dorsal telencephalon and leads to lethal hydrocephalus. Cereb Cortex. 2013 Aug;23(8):1824-35 |
1 | J:110263 Smith KM, Ohkubo Y, Maragnoli ME, Rasin MR, Schwartz ML, Sestan N, Vaccarino FM, Midline radial glia translocation and corpus callosum formation require FGF signaling. Nat Neurosci. 2006 Jun;9(6):787-97 |
1 | J:214381 Spiegel I, Mardinly AR, Gabel HW, Bazinet JE, Couch CH, Tzeng CP, Harmin DA, Greenberg ME, Npas4 regulates excitatory-inhibitory balance within neural circuits through cell-type-specific gene programs. Cell. 2014 May 22;157(5):1216-29 |
1 | J:241169 Stergiopoulos A, Politis PK, Nuclear receptor NR5A2 controls neural stem cell fate decisions during development. Nat Commun. 2016 Jul 22;7:12230 |
1 | J:159839 Stevens HE, Smith KM, Maragnoli ME, Fagel D, Borok E, Shanabrough M, Horvath TL, Vaccarino FM, Fgfr2 is required for the development of the medial prefrontal cortex and its connections with limbic circuits. J Neurosci. 2010 Apr 21;30(16):5590-602 |
1 | J:106946 Stocker AM, Chenn A, Differential expression of alpha-E-catenin and alpha-N-catenin in the developing cerebral cortex. Brain Res. 2006 Feb 16;1073-1074:151-8 |
1 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1 | J:319547 Taib S, Lamande N, Martin S, Coulpier F, Topilko P, Brunet I, Myelinating Schwann cells and Netrin-1 control intra-nervous vascularization of the developing mouse sciatic nerve. Elife. 2022 Jan 12;11:e64773 |
1* | J:82445 Talamillo A, Quinn JC, Collinson JM, Caric D, Price DJ, West JD, Hill RE, Pax6 regulates regional development and neuronal migration in the cerebral cortex. Dev Biol. 2003 Mar 1;255(1):151-63 |
1 | J:360973 Tang I, Nisal A, Reed A, Ware TB, Johansen A, Zaki MS, Cravatt BF, Gleeson JG, Lipidomic profiling of mouse brain and human neuron cultures reveals a role for Mboat7 in mTOR-dependent neuronal migration. Sci Transl Med. 2025 Jan;17(779):eadp5247 |
1 | J:308784 Tang Q, Xie MY, Zhang YL, Xue RY, Zhu XH, Yang H, Targeted deletion of Atoh8 results in severe hearing loss in mice. Genesis. 2021 Aug 17;:e23442 |
1 | J:278287 Tang T, Zhang Y, Wang Y, Cai Z, Lu Z, Li L, Huang R, Hagelkruys A, Matthias P, Zhang H, Seiser C, Xie Y, HDAC1 and HDAC2 Regulate Intermediate Progenitor Positioning to Safeguard Neocortical Development. Neuron. 2019 Mar 20;101(6):1117-1133.e5 |
1 | J:338930 Tarnick J, Elhendawi M, Holland I, Chang Z, Davies JA, Innervation of the developing kidney in vivo and in vitro. Biol Open. 2023 Aug 15;12(8) |
1 | J:97371 Theriault FM, Nuthall HN, Dong Z, Lo R, Barnabe-Heider F, Miller FD, Stifani S, Role for Runx1 in the proliferation and neuronal differentiation of selected progenitor cells in the mammalian nervous system. J Neurosci. 2005 Feb 23;25(8):2050-61 |
2 | J:154456 Thompson H, Andrews W, Parnavelas JG, Erskine L, Robo2 is required for Slit-mediated intraretinal axon guidance. Dev Biol. 2009 Nov 15;335(2):418-26 |
2 | J:111137 Thompson H, Camand O, Barker D, Erskine L, Slit proteins regulate distinct aspects of retinal ganglion cell axon guidance within dorsal and ventral retina. J Neurosci. 2006 Aug 2;26(31):8082-91 |
1 | J:173842 Tian Y, Lei L, Minden A, A key role for Pak4 in proliferation and differentiation of neural progenitor cells. Dev Biol. 2011 May 15;353(2):206-16 |
1 | J:45303 Tole S, Christian C, Grove EA, Early specification and autonomous development of cortical fields in the mouse hippocampus. Development. 1997 Dec;124(24):4959-70 |
1 | J:343099 Tonosaki M, Fujimori A, Yaoi T, Itoh K, Loss of Aspm causes increased apoptosis of developing neural cells during mouse cerebral corticogenesis. PLoS One. 2023;18(11):e0294893 |
1 | J:268904 Tripathy R, Leca I, van Dijk T, Weiss J, van Bon BW, Sergaki MC, Gstrein T, Breuss M, Tian G, Bahi-Buisson N, Paciorkowski AR, Pagnamenta AT, Wenninger-Weinzierl A, Martinez-Reza MF, Landler L, Lise S, Taylor JC, Terrone G, Vitiello G, Del Giudice E, Brunetti-Pierri N, D'Amico A, Reymond A, Voisin N, Bernstein JA, Farrelly E, Kini U, Leonard TA, Valence S, Burglen L, Armstrong L, Hiatt SM, Cooper GM, Aldinger KA, Dobyns WB, Mirzaa G, Pierson TM, Baas F, Chelly J, Cowan NJ, Keays DA, Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations. Neuron. 2018 Dec 19;100(6):1354-1368.e5 |
1 | J:363296 Tsampoula M, Tarampoulous I, Manolakou T, Ninou E, Politis PK, The Neurodevelopmental Disorders Associated Gene Rnf113a Regulates Survival and Differentiation Properties of Neural Stem Cells. Stem Cells. 2022 Jul 27;40(7):678-690 |
1 | J:277336 Turco AE, Cadena MT, Zhang HL, Sandhu JK, Oakes SR, Chathurvedula T, Peterson RE, Keast JR, Vezina CM, A temporal and spatial map of axons in developing mouse prostate. Histochem Cell Biol. 2019 Jul;152(1):35-45 |
1 | J:309494 Velazquez FN, Prucca CG, Etienne O, D'Astolfo DS, Silvestre DC, Boussin FD, Caputto BL, Brain development is impaired in c-fos -/- mice. Oncotarget. 2015 Jul 10;6(19):16883-901 |
1 | J:143244 Vitalis T, Laine J, Simon A, Roland A, Leterrier C, Lenkei Z, The type 1 cannabinoid receptor is highly expressed in embryonic cortical projection neurons and negatively regulates neurite growth in vitro. Eur J Neurosci. 2008 Nov;28(9):1705-18 |
1 | J:265679 Wang B, Joo JH, Mount R, Teubner BJW, Krenzer A, Ward AL, Ichhaporia VP, Adams EJ, Khoriaty R, Peters ST, Pruett-Miller SM, Zakharenko SS, Ginsburg D, Kundu M, The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018 Aug 1;128(8):3319-3332 |
1 | J:139368 Wang G, Krishnamurthy K, Chiang YW, Dasgupta S, Bieberich E, Regulation of neural progenitor cell motility by ceramide and potential implications for mouse brain development. J Neurochem. 2008 Jul;106(2):718-33 |
1 | J:164874 Wang L, Vervoort V, Wallez Y, Core N, Cremer H, Pasquale EB, The SRC homology 2 domain protein Shep1 plays an important role in the penetration of olfactory sensory axons into the forebrain. J Neurosci. 2010 Sep 29;30(39):13201-10 |
1 | J:235720 Wang PS, Chou FS, Ramachandran S, Xia S, Chen HY, Guo F, Suraneni P, Maher BJ, Li R, Crucial roles of the Arp2/3 complex during mammalian corticogenesis. Development. 2016 Aug 1;143(15):2741-52 |
1 | J:199796 Wang SZ, Ibrahim LA, Kim YJ, Gibson DA, Leung HC, Yuan W, Zhang KK, Tao HW, Ma L, Zhang LI, Slit/Robo Signaling Mediates Spatial Positioning of Spiral Ganglion Neurons during Development of Cochlear Innervation. J Neurosci. 2013 Jul 24;33(30):12242-54 |
1 | J:302429 Wang Z, Jung JS, Inbar TC, Rangoussis KM, Faaborg-Andersen C, Coate TM, The Purinergic Receptor P2rx3 is Required for Spiral Ganglion Neuron Branch Refinement during Development. eNeuro. 2020 Jul/Aug;7(4):ENEURO.0179-20.2020 |
1 | J:259982 Weng PL, Vinjamuri M, Ovitt CE, Ascl3 transcription factor marks a distinct progenitor lineage for non-neuronal support cells in the olfactory epithelium. Sci Rep. 2016 Dec 2;6:38199 |
1* | J:241446 Xiang X, Zhuang X, Li S, Shi L, Arhgef1 is expressed in cortical neural progenitor cells and regulates neurite outgrowth of newly differentiated neurons. Neurosci Lett. 2017 Jan 18;638:27-34 |
1 | J:202407 Xiao Y, Woo WM, Nagao K, Li W, Terunuma A, Mukouyama YS, Oro AE, Vogel JC, Brownell I, Perivascular hair follicle stem cells associate with a venule annulus. J Invest Dermatol. 2013 Oct;133(10):2324-31 |
1 | J:273281 Xu D, Yao M, Wang Y, Yuan L, Hoeck JD, Yu J, Liu L, Yeap YYC, Zhang W, Zhang F, Feng Y, Ma T, Wang Y, Ng DCH, Niu X, Su B, Behrens A, Xu Z, MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis. PLoS Biol. 2018 Dec;16(12):e2006613 |
1 | J:264125 Xu Z, Liang Q, Song X, Zhang Z, Lindtner S, Li Z, Wen Y, Liu G, Guo T, Qi D, Wang M, Wang C, Li H, You Y, Wang X, Chen B, Feng H, Rubenstein JL, Yang Z, SP8 and SP9 coordinately promote D2-type medium spiny neuron production by activating Six3 expression. Development. 2018 Jul 23;145(14):dev165456 |
1 | J:270427 Yabut OR, Fernandez G, Huynh T, Yoon K, Pleasure SJ, Suppressor of Fused Is Critical for Maintenance of Neuronal Progenitor Identity during Corticogenesis. Cell Rep. 2015 Sep 29;12(12):2021-34 |
1 | J:282462 Yabut OR, Ng HX, Fernandez G, Yoon K, Kuhn J, Pleasure SJ, Loss of Suppressor of Fused in Mid-Corticogenesis Leads to the Expansion of Intermediate Progenitors. J Dev Biol. 2016 Dec;4(4) |
1* | J:214315 Yamada M, Clark J, Iulianella A, MLLT11/AF1q is differentially expressed in maturing neurons during development. Gene Expr Patterns. 2014 Jul;15(2):80-7 |
1 | J:209314 Yamamoto H, Maruo T, Majima T, Ishizaki H, Tanaka-Okamoto M, Miyoshi J, Mandai K, Takai Y, Genetic deletion of afadin causes hydrocephalus by destruction of adherens junctions in radial glial and ependymal cells in the midbrain. PLoS One. 2013;8(11):e80356 |
2 | J:345074 Yamanaka T, Kurosawa M, Yoshida A, Shimogori T, Hiyama A, Maity SN, Hattori N, Matsui H, Nukina N, The transcription factor NF-YA is crucial for neural progenitor maintenance during brain development. J Biol Chem. 2024 Jan 8;300(2):105629 |
1 | J:221409 Yang M, Yang SL, Herrlinger S, Liang C, Dzieciatkowska M, Hansen KC, Desai R, Nagy A, Niswander L, Moss EG, Chen JF, Lin28 promotes the proliferative capacity of neural progenitor cells in brain development. Development. 2015 May 1;142(9):1616-27 |
1 | J:110232 Yoshimatsu T, Kawaguchi D, Oishi K, Takeda K, Akira S, Masuyama N, Gotoh Y, Non-cell-autonomous action of STAT3 in maintenance of neural precursor cells in the mouse neocortex. Development. 2006 Jul;133(13):2553-63 |
1 | J:316159 Yu Q, Du M, Zhang W, Liu L, Gao Z, Chen W, Gu Y, Zhu K, Niu X, Sun Q, Wang L, Mesenteric Neural Crest Cells Are the Embryological Basis of Skip Segment Hirschsprung's Disease. Cell Mol Gastroenterol Hepatol. 2021;12(1):1-24 |
1 | J:363160 Yuizumi N, Harada Y, Kuniya T, Sunabori T, Koike M, Wakabayashi M, Ishihama Y, Suzuki Y, Kawaguchi D, Gotoh Y, Maintenance of neural stem-progenitor cells by the lysosomal biosynthesis regulators TFEB and TFE3 in the embryonic mouse telencephalon. Stem Cells. 2021 Jul;39(7):929-944 |
1 | J:299730 Zhang L, Jing H, Li H, Chen W, Luo B, Zhang H, Dong Z, Li L, Su H, Xiong WC, Mei L, Neddylation is critical to cortical development by regulating Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2020 Oct 20;117(42):26448-26459 |
1 | J:328995 Zhang SF, Dai SK, Du HZ, Wang H, Li XG, Tang Y, Liu CM, The epigenetic state of EED-Gli3-Gli1 regulatory axis controls embryonic cortical neurogenesis. Stem Cell Reports. 2022 Sep 13;17(9):2064-2080 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
1 | J:324298 Zhou J, Liu G, Zhang X, Wu C, Ma M, Wu J, Hou L, Yin B, Qiang B, Shu P, Peng X, Comparison of the Spatiotemporal Expression Patterns of Three Cre Lines, Emx1IRES-Cre, D6-Cre and hGFAP-Cre, Commonly Used in Neocortical Development Research. Cereb Cortex. 2022 Apr 5;32(8):1668-1681 |
1 | J:310644 Zhu Q, Chen L, Li Y, Huang M, Shao J, Li S, Cheng J, Yang H, Wu Y, Zhang J, Feng J, Fan M, Wu H, Rack1 is essential for corticogenesis by preventing p21-dependent senescence in neural stem cells. Cell Rep. 2021 Aug 31;36(9):109639 |
Tubb4a tubulin, beta 4A class IVA (Synonyms: Tubb, Tubb4) | |
Results | Reference |
1* | J:196330 Breuss M, Heng JI, Poirier K, Tian G, Jaglin XH, Qu Z, Braun A, Gstrein T, Ngo L, Haas M, Bahi-Buisson N, Moutard ML, Passemard S, Verloes A, Gressens P, Xie Y, Robson KJ, Rani DS, Thangaraj K, Clausen T, Chelly J, Cowan NJ, Keays DA, Mutations in the beta-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities. Cell Rep. 2012 Dec 27;2(6):1554-62 |
1 | J:315450 Giridhar PV, Bell SM, Sridharan A, Rajavelu P, Kitzmiller JA, Na CL, Kofron M, Brandt EB, Ericksen M, Naren AP, Moon C, Khurana Hershey GK, Whitsett JA, Airway Epithelial KIF3A Regulates Th2 Responses to Aeroallergens. J Immunol. 2016 Dec 1;197(11):4228-4239 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
2 | J:217677 Snitow ME, Li S, Morley MP, Rathi K, Lu MM, Kadzik RS, Stewart KM, Morrisey EE, Ezh2 represses the basal cell lineage during lung endoderm development. Development. 2015 Jan 1;142(1):108-17 |
1 | J:55155 Tichelaar JW, Wert SE, Costa RH, Kimura S, Whitsett JA, HNF-3/forkhead homologue-4 (HFH-4) is expressed in ciliated epithelial cells in the developing mouse lung. J Histochem Cytochem. 1999 Jun;47(6):823-32 |
Tubb4b tubulin, beta 4B class IVB (Synonyms: 4930542G03Rik, MGC:28623, MGC:6713, Tubb2c) | |
Results | Reference |
1* | J:196330 Breuss M, Heng JI, Poirier K, Tian G, Jaglin XH, Qu Z, Braun A, Gstrein T, Ngo L, Haas M, Bahi-Buisson N, Moutard ML, Passemard S, Verloes A, Gressens P, Xie Y, Robson KJ, Rani DS, Thangaraj K, Clausen T, Chelly J, Cowan NJ, Keays DA, Mutations in the beta-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities. Cell Rep. 2012 Dec 27;2(6):1554-62 |
1 | J:217677 Snitow ME, Li S, Morley MP, Rathi K, Lu MM, Kadzik RS, Stewart KM, Morrisey EE, Ezh2 represses the basal cell lineage during lung endoderm development. Development. 2015 Jan 1;142(1):108-17 |
1 | J:55155 Tichelaar JW, Wert SE, Costa RH, Kimura S, Whitsett JA, HNF-3/forkhead homologue-4 (HFH-4) is expressed in ciliated epithelial cells in the developing mouse lung. J Histochem Cytochem. 1999 Jun;47(6):823-32 |
Tubb5 tubulin, beta 5 class I (Synonyms: B130022C14Rik) | |
Results | Reference |
2* | J:196330 Breuss M, Heng JI, Poirier K, Tian G, Jaglin XH, Qu Z, Braun A, Gstrein T, Ngo L, Haas M, Bahi-Buisson N, Moutard ML, Passemard S, Verloes A, Gressens P, Xie Y, Robson KJ, Rani DS, Thangaraj K, Clausen T, Chelly J, Cowan NJ, Keays DA, Mutations in the beta-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities. Cell Rep. 2012 Dec 27;2(6):1554-62 |
1 | J:330439 Liu H, He L, Cheng Q, Luo W, Zhao T, Yang D, Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states. Int J Mol Med. 2022 Nov;50(5) |
Tubb6 tubulin, beta 6 class V (Synonyms: 2310057H16Rik) | |
Results | Reference |
1* | J:196330 Breuss M, Heng JI, Poirier K, Tian G, Jaglin XH, Qu Z, Braun A, Gstrein T, Ngo L, Haas M, Bahi-Buisson N, Moutard ML, Passemard S, Verloes A, Gressens P, Xie Y, Robson KJ, Rani DS, Thangaraj K, Clausen T, Chelly J, Cowan NJ, Keays DA, Mutations in the beta-tubulin gene TUBB5 cause microcephaly with structural brain abnormalities. Cell Rep. 2012 Dec 27;2(6):1554-62 |
Tubd1 tubulin, delta 1 (Synonyms: 4930550G19Rik) | |
Results | Reference |
1 | J:213437 Storbeck M, Hupperich K, Gaspar JA, Meganathan K, Martinez Carrera L, Wirth R, Sachinidis A, Wirth B, Neuronal-specific deficiency of the splicing factor Tra2b causes apoptosis in neurogenic areas of the developing mouse brain. PLoS One. 2014;9(2):e89020 |
Tubg1 tubulin, gamma 1 (Synonyms: 1500010O08Rik, MGC:8041) | |
Results | Reference |
1 | J:306061 Damen M, Wirtz L, Soroka E, Khatif H, Kukat C, Simons BD, Bazzi H, High proliferation and delamination during skin epidermal stratification. Nat Commun. 2021 May 28;12(1):3227 |
1 | J:206576 Fukuda T, Kominami K, Wang S, Togashi H, Hirata K, Mizoguchi A, Rikitake Y, Takai Y, Aberrant cochlear hair cell attachments caused by Nectin-3 deficiency result in hair bundle abnormalities. Development. 2014 Jan;141(2):399-409 |
1 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
1 | J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6 |
1 | J:131308 Jones C, Roper VC, Foucher I, Qian D, Banizs B, Petit C, Yoder BK, Chen P, Ciliary proteins link basal body polarization to planar cell polarity regulation. Nat Genet. 2008 Jan;40(1):69-77 |
1 | J:169934 Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A, Hoki Y, Fujiyama A, Shibata T, Sado T, Noce T, Nakano T, Nakatsuji N, Lin H, Sasaki H, MITOPLD Is a Mitochondrial Protein Essential for Nuage Formation and piRNA Biogenesis in the Mouse Germline. Dev Cell. 2011 Mar 15;20(3):364-75 |
Tubg2 tubulin, gamma 2 (Synonyms: Tubgl) | |
Results | Reference |
1 | J:206576 Fukuda T, Kominami K, Wang S, Togashi H, Hirata K, Mizoguchi A, Rikitake Y, Takai Y, Aberrant cochlear hair cell attachments caused by Nectin-3 deficiency result in hair bundle abnormalities. Development. 2014 Jan;141(2):399-409 |
1 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
1 | J:343289 Ho KH, Candat A, Scarpetta V, Faucourt M, Weill S, Salio C, D'Este E, Meschkat M, Wurm CA, Kneussel M, Janke C, Magiera MM, Genovesio A, Meunier A, Sassoe-Pognetto M, Brill MS, Spassky N, Patrizi A, Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage. Dev Cell. 2023 Dec 4;58(23):2641-2651.e6 |
1 | J:131308 Jones C, Roper VC, Foucher I, Qian D, Banizs B, Petit C, Yoder BK, Chen P, Ciliary proteins link basal body polarization to planar cell polarity regulation. Nat Genet. 2008 Jan;40(1):69-77 |
1* | J:346057 Lu D, Zhi Y, Su H, Lin X, Lin J, Shi Y, Yi W, Hong C, Zhang T, Fu Z, Chen LY, Zhao Z, Li R, Xu Z, Chen W, Wang N, Xu D, ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells. Cell Rep. 2024 Feb 24;43(3):113818 |
1 | J:169934 Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A, Hoki Y, Fujiyama A, Shibata T, Sado T, Noce T, Nakano T, Nakatsuji N, Lin H, Sasaki H, MITOPLD Is a Mitochondrial Protein Essential for Nuage Formation and piRNA Biogenesis in the Mouse Germline. Dev Cell. 2011 Mar 15;20(3):364-75 |
Tuft1 tuftelin 1 | |
Results | Reference |
1* | J:39157 Zeichner-David M, Vo H, Tan H, Diekwisch T, Berman B, Thiemann F , Alcocer MD , Hsu P , Wang T , Eyna J , Caton J , Slavkin HC , MacDougall M, Timing of the expression of enamel gene products during mouse tooth development. Int J Dev Biol. 1997 Feb;41(1):27-38 |
Tulp3 TUB like protein 3 (Synonyms: 2310022L06Rik) | |
Results | Reference |
1* | J:356303 Zhao Y, Zheng D, Cvekl A, A comprehensive spatial-temporal transcriptomic analysis of differentiating nascent mouse lens epithelial and fiber cells. Exp Eye Res. 2018 Oct;175:56-72 |
Tulp4 TUB like protein 4 (Synonyms: 1110057P05Rik, 2210038L17Rik) | |
Results | Reference |
1* | J:353281 Rybiczka-Tesulov M, Garritsen O, Veno MT, Wieg L, Dijk RV, Rahimi K, Gomes-Duarte A, Wit M, van de Haar LL, Michels L, van Kronenburg NCH, van der Meer C, Kjems J, Vangoor VR, Pasterkamp RJ, Circular RNAs regulate neuron size and migration of midbrain dopamine neurons during development. Nat Commun. 2024 Aug 8;15(1):6773 |
Twist1 twist basic helix-loop-helix transcription factor 1
(Synonyms:
bHLHa38, charlie chaplin, M-Twist, pdt, Pluridigite, Ska10, Ska | |
Results | Reference |
1 | J:47975 Bourgeois P, Bolcato-Bellemin AL, Danse JM, Bloch-Zupan A, Yoshiba K, Stoetzel C, Perrin-Schmitt F, The variable expressivity and incomplete penetrance of the twist-null heterozygous mouse phenotype resemble those of human Saethre-Chotzen syndrome. Hum Mol Genet. 1998 Jun;7(6):945-57 |
1* | J:30097 Fuchtbauer EM, Expression of M-twist during postimplantation development of the mouse. Dev Dyn. 1995 Nov;204(3):316-22 |
1* | J:236374 Goldie SJ, Arhatari BD, Anderson P, Auden A, Partridge DD, Jane SM, Dworkin S, Mice lacking the conserved transcription factor Grainyhead-like 3 (Grhl3) display increased apposition of the frontal and parietal bones during embryonic development. BMC Dev Biol. 2016 Oct 18;16(1):37 |
2 | J:114686 Hinoi E, Bialek P, Chen YT, Rached MT, Groner Y, Behringer RR, Ornitz DM, Karsenty G, Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes Dev. 2006 Nov 1;20(21):2937-42 |
1* | J:292270 Ideno H, Nakashima K, Komatsu K, Araki R, Abe M, Arai Y, Kimura H, Shinkai Y, Tachibana M, Nifuji A, G9a is involved in the regulation of cranial bone formation through activation of Runx2 function during development. Bone. 2020 Aug;137:115332 |
1* | J:61352 Johnson D, Iseki S, Wilkie AO, Morriss-Kay GM, Expression patterns of Twist and Fgfr1, -2 and -3 in the developing mouse coronal suture suggest a key role for twist in suture initiation and biogenesis. Mech Dev. 2000 Mar 1;91(1-2):341-5 |
1 | J:233640 Kyrylkova K, Iwaniec UT, Philbrick KA, Leid M, BCL11B regulates sutural patency in the mouse craniofacial skeleton. Dev Biol. 2016 Jul 15;415(2):251-60 |
1 | J:254756 Lei R, Zhang K, Wei Y, Chen M, Weinstein LS, Hong Y, Zhu M, Li H, Li H, G-Protein alpha-Subunit Gsalpha Is Required for Craniofacial Morphogenesis. PLoS One. 2016;11(2):e0147535 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1 | J:242579 Malek R, Gajula RP, Williams RD, Nghiem B, Simons BW, Nugent K, Wang H, Taparra K, Lemtiri-Chlieh G, Yoon AR, True L, An SS, DeWeese TL, Ross AE, Schaeffer EM, Pienta KJ, Hurley PJ, Morrissey C, Tran PT, TWIST1-WDR5-Hottip Regulates Hoxa9 Chromatin to Facilitate Prostate Cancer Metastasis. Cancer Res. 2017 Jun 15;77(12):3181-3193 |
1 | J:266862 Morosan-Puopolo G, Balakrishnan-Renuka A, Yusuf F, Chen J, Dai F, Zoidl G, Ludtke TH, Kispert A, Theiss C, Abdelsabour-Khalaf M, Brand-Saberi B, Wnt11 is required for oriented migration of dermogenic progenitor cells from the dorsomedial lip of the avian dermomyotome. PLoS One. 2014;9(3):e92679 |
1 | J:78407 O'Rourke MP, Soo K, Behringer RR, Hui CC, Tam PP, Twist plays an essential role in FGF and SHH signal transduction during mouse limb development. Dev Biol. 2002 Aug 1;248(1):143-56 |
1 | J:326535 Petitpre C, Faure L, Uhl P, Fontanet P, Filova I, Pavlinkova G, Adameyko I, Hadjab S, Lallemend F, Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification. Nat Commun. 2022 Jul 5;13(1):3878 |
1 | J:163175 Rice DP, Connor EC, Veltmaat JM, Lana-Elola E, Veistinen L, Tanimoto Y, Bellusci S, Rice R, Gli3Xt-J/Xt-J mice exhibit lambdoid suture craniosynostosis which results from altered osteoprogenitor proliferation and differentiation. Hum Mol Genet. 2010 Sep 1;19(17):3457-67 |
1 | J:100235 Rice R, Thesleff I, Rice DP, Regulation of Twist, Snail, and Id1 is conserved between the developing murine palate and tooth. Dev Dyn. 2005 Sep;234(1):28-35 |
1* | J:316953 Suzuki M, Sato F, Bhawal UK, The basic helix-loop-helix (bHLH) transcription factor DEC2 negatively regulates Twist1 through an E-box element. Biochem Biophys Res Commun. 2014 Dec 12;455(3-4):390-5 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
1* | J:338932 You Y, Grasso E, Alvero A, Condon J, Dimova T, Hu A, Ding J, Alexandrova M, Manchorova D, Dimitrova V, Liao A, Mor G, Twist1-IRF9 Interaction Is Necessary for IFN-Stimulated Gene Anti-Zika Viral Infection. J Immunol. 2023 May 5;210(12):1899-1912 |
1* | J:140474 Yu W, Kamara H, Svoboda KK, The role of twist during palate development. Dev Dyn. 2008 Oct;237(10):2716-25 |
Twist2 twist basic helix-loop-helix transcription factor 2 (Synonyms: bHLHa39, Dermo1) | |
Results | Reference |
1 | J:119323 Atit R, Sgaier SK, Mohamed OA, Taketo MM, Dufort D, Joyner AL, Niswander L, Conlon RA, Beta-catenin activation is necessary and sufficient to specify the dorsal dermal fate in the mouse. Dev Biol. 2006 Aug 1;296(1):164-76 |
1* | J:292270 Ideno H, Nakashima K, Komatsu K, Araki R, Abe M, Arai Y, Kimura H, Shinkai Y, Tachibana M, Nifuji A, G9a is involved in the regulation of cranial bone formation through activation of Runx2 function during development. Bone. 2020 Aug;137:115332 |
1* | J:29655 Li L, Cserjesi P, Olson EN, Dermo-1: a novel twist-related bHLH protein expressed in the developing dermis. Dev Biol. 1995 Nov;172(1):280-92 |
1 | J:266862 Morosan-Puopolo G, Balakrishnan-Renuka A, Yusuf F, Chen J, Dai F, Zoidl G, Ludtke TH, Kispert A, Theiss C, Abdelsabour-Khalaf M, Brand-Saberi B, Wnt11 is required for oriented migration of dermogenic progenitor cells from the dorsomedial lip of the avian dermomyotome. PLoS One. 2014;9(3):e92679 |
1 | J:171395 Weaving L, Mihelec M, Storen R, Sosic D, Grigg JR, Tam PP, Jamieson RV, Twist2: role in corneal stromal keratocyte proliferation and corneal thickness. Invest Ophthalmol Vis Sci. 2010 Nov;51(11):5561-70 |
Txlng taxilin gamma (Synonyms: 4932441K18Rik, Fiat) | |
Results | Reference |
1* | J:148804 Yu VW, Akhouayri O, St-Arnaud R, FIAT is co-expressed with its dimerization target ATF4 in early osteoblasts, but not in osteocytes. Gene Expr Patterns. 2009 Jun;9(5):335-40 |
Txn1 thioredoxin 1 (Synonyms: Trx1) | |
Results | Reference |
1 | J:74095 Kobayashi M, Nakamura H, Yodoi J, Shiota K, Immunohistochemical localization of thioredoxin and glutaredoxin in mouse embryos and fetuses. Antioxid Redox Signal. 2000 Winter;2(4):653-63 |
1 | J:74208 Kobayashi M, Nakamura H, Yodoi J, Shiota K, Ontogenesis of anti-oxidative enzymes in mouse embryos and fetuses: an immunohistochemical study. Ital J Anat Embryol. 2001;106(2 Suppl 2):137-42 |
1* | J:227089 Pirson M, Knoops B, Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617 |
Txn2 thioredoxin 2 (Synonyms: 2510006J11Rik, Trx2) | |
Results | Reference |
1 | J:74095 Kobayashi M, Nakamura H, Yodoi J, Shiota K, Immunohistochemical localization of thioredoxin and glutaredoxin in mouse embryos and fetuses. Antioxid Redox Signal. 2000 Winter;2(4):653-63 |
1 | J:74208 Kobayashi M, Nakamura H, Yodoi J, Shiota K, Ontogenesis of anti-oxidative enzymes in mouse embryos and fetuses: an immunohistochemical study. Ital J Anat Embryol. 2001;106(2 Suppl 2):137-42 |
1* | J:227089 Pirson M, Knoops B, Expression of peroxiredoxins and thioredoxins in the mouse spinal cord during embryonic development. J Comp Neurol. 2015 Dec 1;523(17):2599-617 |
1* | J:345131 Schraps N, Tirre M, Pyschny S, Reis A, Schlierbach H, Seidl M, Kehl HG, Schanzer A, Heger J, Jux C, Drenckhahn JD, Cardiomyocyte maturation alters molecular stress response capacities and determines cell survival upon mitochondrial dysfunction. Free Radic Biol Med. 2024 Jan 22;213:248-265 |
Txnrd3 thioredoxin reductase 3 (Synonyms: Tgr, TR2) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Tyr tyrosinase (Synonyms: Oca1, skc35) | |
Results | Reference |
1* | J:25 Beermann F, Schmid E, Schutz G, Expression of the mouse tyrosinase gene during embryonic development: recapitulation of the temporal regulation in transgenic mice. Proc Natl Acad Sci U S A. 1992 Apr 1;89(7):2809-13 |
1 | J:288683 Gacem N, Kavo A, Zerad L, Richard L, Mathis S, Kapur RP, Parisot M, Amiel J, Dufour S, de la Grange P, Pingault V, Vallat JM, Bondurand N, ADAR1 mediated regulation of neural crest derived melanocytes and Schwann cell development. Nat Commun. 2020 Jan 10;11(1):198 |
1 | J:250180 Nakagawa N, Yagi H, Kato K, Takematsu H, Oka S, Ectopic clustering of Cajal-Retzius and subplate cells is an initial pathological feature in Pomgnt2-knockout mice, a model of dystroglycanopathy. Sci Rep. 2015 Jun 10;5:11163 |
1 | J:357839 Nasim S, Abujamra BA, Chaparro D, Nogueira PDS, Riva A, Hutcheson JD, Kos L, Multiple cell types including melanocytes contribute to elastogenesis in the developing murine aortic valve. Sci Rep. 2024 Oct 26;14(1):25481 |
Tyrp1 tyrosinase-related protein 1 (Synonyms: isa, Oca3, TRP-1, TRP1, Tyrp) | |
Results | Reference |
1 | J:357839 Nasim S, Abujamra BA, Chaparro D, Nogueira PDS, Riva A, Hutcheson JD, Kos L, Multiple cell types including melanocytes contribute to elastogenesis in the developing murine aortic valve. Sci Rep. 2024 Oct 26;14(1):25481 |
Uba1 ubiquitin-like modifier activating enzyme 1 (Synonyms: A1S9, Sbx, Ube-1) | |
Results | Reference |
1 | J:330439 Liu H, He L, Cheng Q, Luo W, Zhao T, Yang D, Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states. Int J Mol Med. 2022 Nov;50(5) |
1* | J:36991 Odorisio T, Mahadevaiah SK, McCarrey JR, Burgoyne PS, Transcriptional analysis of the candidate spermatogenesis gene Ube1y and of the closely related Ube1x shows that they are coexpressed in spermatogonia and spermatids but are repressed in pachytene spermatocytes. Dev Biol. 1996 Nov 25;180(1):336-43 |
Uba1y ubiquitin-activating enzyme, Chr Y (Synonyms: A1s9Y-1, Sby, Ube1y-1, Ube1y1, Ube-2) | |
Results | Reference |
1* | J:36991 Odorisio T, Mahadevaiah SK, McCarrey JR, Burgoyne PS, Transcriptional analysis of the candidate spermatogenesis gene Ube1y and of the closely related Ube1x shows that they are coexpressed in spermatogonia and spermatids but are repressed in pachytene spermatocytes. Dev Biol. 1996 Nov 25;180(1):336-43 |
Uba2 ubiquitin-like modifier activating enzyme 2 (Synonyms: anthracycline-associated resistance, Arx, SAE2, Sumo-1 activating enzyme subunit 2, UBA2, Uble1b) | |
Results | Reference |
1* | J:356303 Zhao Y, Zheng D, Cvekl A, A comprehensive spatial-temporal transcriptomic analysis of differentiating nascent mouse lens epithelial and fiber cells. Exp Eye Res. 2018 Oct;175:56-72 |
Uba5 ubiquitin-like modifier activating enzyme 5 (Synonyms: 5730525G14Rik, Ube1dc1) | |
Results | Reference |
1* | J:272566 Yang R, Wang H, Kang B, Chen B, Shi Y, Yang S, Sun L, Liu Y, Xiao W, Zhang T, Yang J, Zhang Y, Zhu M, Xu P, Chang Y, Jia Y, Huang Y, CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235 |
Uba52 ubiquitin A-52 residue ribosomal protein fusion product 1 (Synonyms: D8Ertd21e) | |
Results | Reference |
2 | J:330439 Liu H, He L, Cheng Q, Luo W, Zhao T, Yang D, Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states. Int J Mol Med. 2022 Nov;50(5) |
Ubap1 ubiquitin-associated protein 1 (Synonyms: 2700092A01Rik, NAG20) | |
Results | Reference |
2* | J:346057 Lu D, Zhi Y, Su H, Lin X, Lin J, Shi Y, Yi W, Hong C, Zhang T, Fu Z, Chen LY, Zhao Z, Li R, Xu Z, Chen W, Wang N, Xu D, ESCRT-I protein UBAP1 controls ventricular expansion and cortical neurogenesis via modulating adherens junctions of radial glial cells. Cell Rep. 2024 Feb 24;43(3):113818 |
Ubc ubiquitin C (Synonyms: 2700054O04Rik) | |
Results | Reference |
2 | J:330439 Liu H, He L, Cheng Q, Luo W, Zhao T, Yang D, Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states. Int J Mol Med. 2022 Nov;50(5) |
Ube2b ubiquitin-conjugating enzyme E2B (Synonyms: E2-14k, HR6B, Rad6b) | |
Results | Reference |
1* | J:363656 Barish S, Berg K, Drozd J, Berglund-Brown I, Khizir L, Wasson LK, Seidman CE, Seidman JG, Chen S, Brueckner M, The H2Bub1-deposition complex is required for human and mouse cardiogenesis. Development. 2023 Dec 1;150(23) |
Ube2c ubiquitin-conjugating enzyme E2C (Synonyms: 1110015A16Rik, D2Ertd695e) | |
Results | Reference |
1 | J:330439 Liu H, He L, Cheng Q, Luo W, Zhao T, Yang D, Validation of superior reference genes in mouse submandibular glands under developmental and functional regeneration states. Int J Mol Med. 2022 Nov;50(5) |
1* | J:154087 Trimarchi JM, Stadler MB, Cepko CL, Individual retinal progenitor cells display extensive heterogeneity of gene expression. PLoS One. 2008;3(2):e1588 |
Ube2e1 ubiquitin-conjugating enzyme E2E 1 (Synonyms: Ubce5, ubcM2, UbcM3) | |
Results | Reference |
2* | J:314569 Yanjiang X, Hongjuan H, Tiantian G, Yan Z, Zhijun H, Qiong W, Expression patterns of ubiquitin conjugating enzyme UbcM2 during mouse embryonic development. Gene Expr. 2012;15(4):163-70 |
Ube2l3 ubiquitin-conjugating enzyme E2L 3 (Synonyms: Ubce7, UbcM4) | |
Results | Reference |
1* | J:36254 Harbers K, Muller U, Grams A, Li E, Jaenisch R, Franz T, Provirus integration into a gene encoding a ubiquitin-conjugating enzyme results in a placental defect and embryonic lethality. Proc Natl Acad Sci U S A. 1996 Oct 29;93(22):12412-7 |
Ube2n ubiquitin-conjugating enzyme E2N (Synonyms: 1500026J17Rik, UBC13) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Ube2q1 ubiquitin-conjugating enzyme E2Q family member 1 (Synonyms: 1110002C01Rik, 2310012M18Rik, NICE-5, PRO3094) | |
Results | Reference |
1* | J:195898 Grzmil P, Altmann ME, Adham IM, Engel U, Jarry H, Schweyer S, Wolf S, Manz J, Engel W, Embryo implantation failure and other reproductive defects in Ube2q1-deficient female mice. Reproduction. 2013 Jan;145(1):45-56 |
Ube3b ubiquitin protein ligase E3B | |
Results | Reference |
1* | J:203652 Basel-Vanagaite L, Dallapiccola B, Ramirez-Solis R, Segref A, Thiele H, Edwards A, Arends MJ, Miro X, White JK, Desir J, Abramowicz M, Dentici ML, Lepri F, Hofmann K, Har-Zahav A, Ryder E, Karp NA, Estabel J, Gerdin AK, Podrini C, Ingham NJ, Altmuller J,Nurnberg G, Frommolt P, Abdelhak S, Pasmanik-Chor M, Konen O, Kelley RI, Shohat M, Nurnberg P, Flint J, Steel KP, Hoppe T, Kubisch C, Adams DJ, Borck G, Deficiency for the ubiquitin ligase UBE3B in a blepharophimosis-ptosis-intellectual-disability syndrome. Am J Hum Genet. 2012 Dec 7;91(6):998-1010 |
Ubn2 ubinuclein 2 (Synonyms: 2900060J04Rik, 6030408G03Rik, D130059P03Rik) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Ubqln1 ubiquilin 1 (Synonyms: 1110046H03Rik, 1810030E05Rik, D13Ertd372e, DA41, Dsk2, Plic-1, XDRP1) | |
Results | Reference |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Ubr1 ubiquitin protein ligase E3 component n-recognin 1 (Synonyms: E3 alpha) | |
Results | Reference |
1* | J:77750 Kwon YT, Kashina AS, Davydov IV, Hu RG, An JY, Seo JW, Du F, Varshavsky A, An essential role of N-terminal arginylation in cardiovascular development. Science. 2002 Jul 5;297(5578):96-9 |
Ubr2 ubiquitin protein ligase E3 component n-recognin 2 (Synonyms: 9930021A08Rik, E130209G04Rik, ENSMUSG00000043296) | |
Results | Reference |
1* | J:77750 Kwon YT, Kashina AS, Davydov IV, Hu RG, An JY, Seo JW, Du F, Varshavsky A, An essential role of N-terminal arginylation in cardiovascular development. Science. 2002 Jul 5;297(5578):96-9 |
Uchl1 ubiquitin carboxy-terminal hydrolase L1 (Synonyms: PGP 9.5, PGP9.5) | |
Results | Reference |
1* | J:119681 Bates MD, Dunagan DT, Welch LC, Kaul A, Harvey RP, The Hlx homeobox transcription factor is required early in enteric nervous system development. BMC Dev Biol. 2006;6:33 |
1 | J:74213 Bitoh Y, Shimotake T, Sasaki Y, Iwai N, Development of the pelvic floor muscles of murine embryos with anorectal malformations. J Pediatr Surg. 2002 Feb;37(2):224-7 |
1 | J:230425 Bouilloux F, Thireau J, Venteo S, Farah C, Karam S, Dauvilliers Y, Valmier J, Copeland NG, Jenkins NA, Richard S, Marmigere F, Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death. Elife. 2016;5:e11627 |
1 | J:316183 Cai Y, Yoneda M, Tomita T, Kurotani R, Okamoto M, Kido T, Abe H, Mitzner W, Guha A, Kimura S, Transgenically-expressed secretoglobin 3A2 accelerates resolution of bleomycin-induced pulmonary fibrosis in mice. BMC Pulm Med. 2015 Jul 16;15:72 |
1 | J:169302 da Silva S, Hasegawa H, Scott A, Zhou X, Wagner AK, Han BX, Wang F, Proper formation of whisker barrelettes requires periphery-derived Smad4-dependent TGF-{beta} signaling. Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3395-400 |
1 | J:73312 Gong SG, Characterization of olfactory nerve abnormalities in Twirler mice. Differentiation. 2001 Dec;69(1):58-65 |
1 | J:330742 Goodyer WR, Beyersdorf BM, Duan L, van den Berg NS, Mantri S, Galdos FX, Puluca N, Buikema JW, Lee S, Salmi D, Robinson ER, Rogalla S, Cogan DP, Khosla C, Rosenthal EL, Wu SM, In vivo visualization and molecular targeting of the cardiac conduction system. J Clin Invest. 2022 Oct 17;132(20):e156955 |
1* | J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004; |
1* | J:82630 Hall JM, Bell ML, Finger TE, Disruption of sonic hedgehog signaling alters growth and patterning of lingual taste papillae. Dev Biol. 2003 Mar 15;255(2):263-77 |
1* | J:170495 Ikeda K, Kageyama R, Suzuki Y, Kawakami K, Six1 is indispensable for production of functional progenitor cells during olfactory epithelial development. Int J Dev Biol. 2010;54(10):1453-64 |
1* | J:228519 Jia S, Wildner H, Birchmeier C, Insm1 controls the differentiation of pulmonary neuroendocrine cells by repressing Hes1. Dev Biol. 2015 Dec 1;408(1):90-8 |
1 | J:146225 Kameda Y, Ito M, Nishimaki T, Gotoh N, FRS2alpha is required for the separation, migration, and survival of pharyngeal-endoderm derived organs including thyroid, ultimobranchial body, parathyroid, and thymus. Dev Dyn. 2009 Mar;238(3):503-13 |
1* | J:77820 Kameda Y, Nishimaki T, Takeichi M, Chisaka O, Homeobox gene hoxa3 is essential for the formation of the carotid body in the mouse embryos. Dev Biol. 2002 Jul 1;247(1):197-209 |
1* | J:121343 Lahteenmaki M, Kupari J, Airaksinen MS, Increased apoptosis of parasympathetic but not enteric neurons in mice lacking GFRalpha2. Dev Biol. 2007 May 1;305(1):325-32 |
1 | J:95755 Maka M, Stolt CC, Wegner M, Identification of Sox8 as a modifier gene in a mouse model of Hirschsprung disease reveals underlying molecular defect. Dev Biol. 2005 Jan 1;277(1):155-69 |
1 | J:182762 Mundell NA, Plank JL, LeGrone AW, Frist AY, Zhu L, Shin MK, Southard-Smith EM, Labosky PA, Enteric nervous system specific deletion of Foxd3 disrupts glial cell differentiation and activates compensatory enteric progenitors. Dev Biol. 2012 Mar 15;363(2):373-87 |
1* | J:137801 Nakayama A, Miura H, Shindo Y, Kusakabe Y, Tomonari H, Harada S, Expression of the basal cell markers of taste buds in the anterior tongue and soft palate of the mouse embryo. J Comp Neurol. 2008 Jul 10;509(2):211-24 |
1 | J:187391 Pacal M, Bremner R, Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Dev Dyn. 2012 Oct;241(10):1525-44 |
1* | J:316648 Suflita MT, Pfaltzgraff ER, Mundell NA, Pevny LH, Labosky PA, Ground-state transcriptional requirements for skin-derived precursors. Stem Cells Dev. 2013 Jun 15;22(12):1779-88 |
1 | J:98520 Takamoto N, You LR, Moses K, Chiang C, Zimmer WE, Schwartz RJ, Demayo FJ, Tsai MJ, Tsai SY, COUP-TFII is essential for radial and anteroposterior patterning of the stomach. Development. 2005 May;132(9):2179-89 |
1* | J:233757 Treffy RW, Collins D, Hoshino N, Ton S, Katsevman GA, Oleksiak M, Runge EM, Cho D, Russo M, Spec A, Gomulka J, Henkemeyer M, Rochlin MW, Ephrin-B/EphB Signaling Is Required for Normal Innervation of Lingual Gustatory Papillae. Dev Neurosci. 2016;38(2):124-38 |
1 | J:202753 Uesaka T, Nagashimada M, Enomoto H, GDNF signaling levels control migration and neuronal differentiation of enteric ganglion precursors. J Neurosci. 2013 Oct 9;33(41):16372-82 |
1* | J:36520 Wakisaka S, Miyawaki Y, Youn SH, Kato J, Kurisu K, Protein gene-product 9.5 in developing mouse circumvallate papilla: comparison with neuron-specific enolase and calcitonin gene-related peptide. Anat Embryol (Berl). 1996 Oct;194(4):365-72 |
1 | J:81003 Young HM, Bergner AJ, Muller T, Acquisition of neuronal and glial markers by neural crest-derived cells in the mouse intestine. J Comp Neurol. 2003 Jan 27;456(1):1-11 |
Ucma upper zone of growth plate and cartilage matrix associated (Synonyms: 1110017I16Rik) | |
Results | Reference |
1 | J:191689 Gross S, Krause Y, Wuelling M, Vortkamp A, Hoxa11 and Hoxd11 regulate chondrocyte differentiation upstream of Runx2 and Shox2 in mice. PLoS One. 2012;7(8):e43553 |
2* | J:130737 Tagariello A, Luther J, Streiter M, Didt-Koziel L, Wuelling M, Surmann-Schmitt C, Stock M, Adam N, Vortkamp A, Winterpacht A, Ucma - A novel secreted factor represents a highly specific marker for distal chondrocytes. Matrix Biol. 2008 Jan;27(1):3-11 |
1 | J:149459 Wuelling M, Kaiser FJ, Buelens LA, Braunholz D, Shivdasani RA, Depping R, Vortkamp A, Trps1, a regulator of chondrocyte proliferation and differentiation, interacts with the activator form of Gli3. Dev Biol. 2009 Apr 1;328(1):40-53 |
Ucp1 uncoupling protein 1 (mitochondrial, proton carrier) (Synonyms: Slc25a7) | |
Results | Reference |
1 | J:324530 Fonseca TL, Russo SC, Luongo C, Salvatore D, Bianco AC, Inactivation of Type 3 Deiodinase Results in Life-long Changes in the Brown Adipose Tissue Transcriptome in the Male Mouse. Endocrinology. 2022 May 1;163(5) |
1 | J:102703 Fujimoto N, Matsuo N, Sumiyoshi H, Yamaguchi K, Saikawa T, Yoshimatsu H, Yoshioka H, Adiponectin is expressed in the brown adipose tissue and surrounding immature tissues in mouse embryos. Biochim Biophys Acta. 2005 Oct 15;1731(1):1-12 |
1* | J:165681 Hall JA, Ribich S, Christoffolete MA, Simovic G, Correa-Medina M, Patti ME, Bianco AC, Absence of thyroid hormone activation during development underlies a permanent defect in adaptive thermogenesis. Endocrinology. 2010 Sep;151(9):4573-82 |
1 | J:203690 Martinez-Lopez N, Athonvarangkul D, Sahu S, Coletto L, Zong H, Bastie CC, Pessin JE, Schwartz GJ, Singh R, Autophagy in Myf5+ progenitors regulates energy and glucose homeostasis through control of brown fat and skeletal muscle development. EMBO Rep. 2013 Sep;14(9):795-803 |
3* | J:299602 Mayeuf-Louchart A, Lancel S, Sebti Y, Pourcet B, Loyens A, Delhaye S, Duhem C, Beauchamp J, Ferri L, Thorel Q, Boulinguiez A, Zecchin M, Dubois-Chevalier J, Eeckhoute J, Vaughn LT, Roach PJ, Dani C, Pederson BA, Vincent SD, Staels B, Duez H, Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation. Cell Rep. 2019 Nov 5;29(6):1410-1418.e6 |
2* | J:236180 Zhou H, Black SM, Benson TW, Weintraub NL, Chen W, Berardinelli-Seip Congenital Lipodystrophy 2/Seipin Is Not Required for Brown Adipogenesis but Regulates Brown Adipose Tissue Development and Function. Mol Cell Biol. 2016 Aug 1;36(15):2027-38 |
Ufc1 ubiquitin-fold modifier conjugating enzyme 1 (Synonyms: 1110021H02Rik, ESTM29) | |
Results | Reference |
1* | J:272566 Yang R, Wang H, Kang B, Chen B, Shi Y, Yang S, Sun L, Liu Y, Xiao W, Zhang T, Yang J, Zhang Y, Zhu M, Xu P, Chang Y, Jia Y, Huang Y, CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235 |
Ufl1 UFM1 specific ligase 1 (Synonyms: 1810074P20Rik, Maxer, mKIAA0776, Rcad) | |
Results | Reference |
1* | J:272566 Yang R, Wang H, Kang B, Chen B, Shi Y, Yang S, Sun L, Liu Y, Xiao W, Zhang T, Yang J, Zhang Y, Zhu M, Xu P, Chang Y, Jia Y, Huang Y, CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235 |
Ufsp2 UFM1-specific peptidase 2 (Synonyms: 1810047C23Rik) | |
Results | Reference |
1* | J:272566 Yang R, Wang H, Kang B, Chen B, Shi Y, Yang S, Sun L, Liu Y, Xiao W, Zhang T, Yang J, Zhang Y, Zhu M, Xu P, Chang Y, Jia Y, Huang Y, CDK5RAP3, a UFL1 substrate adaptor, is crucial for liver development. Development. 2019 Jan 25;146(2):dev169235 |
Ugcg UDP-glucose ceramide glucosyltransferase (Synonyms: Epcs21, GlcT-1, Ugcgl) | |
Results | Reference |
1* | J:196477 Wang Z, Kirkwood JS, Taylor AW, Stevens JF, Leid M, Ganguli-Indra G, Indra AK, Transcription factor Ctip2 controls epidermal lipid metabolism and regulates expression of genes involved in sphingolipid biosynthesis during skin development. J Invest Dermatol. 2013 Mar;133(3):668-76 |
Ugp2 UDP-glucose pyrophosphorylase 2 (Synonyms: MGC:38262) | |
Results | Reference |
1 | J:285119 Eaton M, Davies AH, Devine J, Zhao X, Simmons DG, Mariusdottir E, Natale DRC, Matyas JR, Bering EA, Workentine ML, Hallgrimsson B, Cross JC, Complex patterns of cell growth in the placenta in normal pregnancy and as adaptations to maternal diet restriction. PLoS One. 2020;15(1):e0226735 |
1 | J:209351 Prashar P, Yadav PS, Samarjeet F, Bandyopadhyay A, Microarray meta-analysis identifies evolutionarily conserved BMP signaling targets in developing long bones. Dev Biol. 2014 May 15;389(2):192-207 |
1 | J:296367 Roberts GAG, Tunster SJ, Characterising the dynamics of placental glycogen stores in the mouse. Placenta. 2020 Sep 15;99:131-140 |
1 | J:156412 Tunster SJ, Tycko B, John RM, The imprinted Phlda2 gene regulates extraembryonic energy stores. Mol Cell Biol. 2010 Jan;30(1):295-306 |
Uhrf1 ubiquitin-like, containing PHD and RING finger domains, 1 (Synonyms: ICBP90, Np95) | |
Results | Reference |
1 | J:324178 Wu Y, Duan P, Wen Y, Zhang J, Wang X, Dong J, Zhao Q, Feng S, Lv C, Guo Y, Namekawa SH, Yuan S, UHRF1 establishes crosstalk between somatic and germ cells in male reproduction. Cell Death Dis. 2022 Apr 19;13(4):377 |
Ulk1 unc-51 like kinase 1 (Synonyms: mKIAA0722, Unc51.1) | |
Results | Reference |
1 | J:233601 Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP, Harwood CA, Byrne C, O'Shaughnessy RF, Bergamaschi D, Constitutive Autophagy and Nucleophagy during Epidermal Differentiation. J Invest Dermatol. 2016 Jul;136(7):1460-70 |
Umod uromodulin (Synonyms: Tamm-Horsfall glycoprotein, THP, Urehd1, urehr4, uromucoid) | |
Results | Reference |
1 | J:154841 Jouret F, Igarashi T, Gofflot F, Wilson PD, Karet FE, Thakker RV, Devuyst O, Comparative ontogeny, processing, and segmental distribution of the renal chloride channel, ClC-5. Kidney Int. 2004 Jan;65(1):198-208 |
Unc5a unc-5 netrin receptor A (Synonyms: mKIAA1976, Unc5h1) | |
Results | Reference |
1* | J:199400 van den Heuvel DM, Hellemons AJ, Pasterkamp RJ, Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain. PLoS One. 2013;8(2):e55828 |
Unc5b unc-5 netrin receptor B (Synonyms: 6330415E02Rik, D10Bwg0792e, Unc5h2) | |
Results | Reference |
1 | J:60833 Alcantara S, Ruiz M, De Castro F, Soriano E, Sotelo C, Netrin 1 acts as an attractive or as a repulsive cue for distinct migrating neurons during the development of the cerebellar system. Development. 2000 Apr;127(7):1359-72 |
2* | J:84360 Dalvin S, Anselmo MA, Prodhan P, Komatsuzaki K, Schnitzer JJ, Kinane TB, Expression of Netrin-1 and its two receptors DCC and UNC5H2 in the developing mouse lung. Gene Expr Patterns. 2003 Jun;3(3):279-83 |
1 | J:193244 Di Meglio T, Kratochwil CF, Vilain N, Loche A, Vitobello A, Yonehara K, Hrycaj SM, Roska B, Peters AH, Eichmann A, Wellik D, Ducret S, Rijli FM, Ezh2 orchestrates topographic migration and connectivity of mouse precerebellar neurons. Science. 2013 Jan 11;339(6116):204-7 |
1* | J:199400 van den Heuvel DM, Hellemons AJ, Pasterkamp RJ, Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain. PLoS One. 2013;8(2):e55828 |
Unc5c unc-5 netrin receptor C (Synonyms: B130051O18Rik, Unc5h3) | |
Results | Reference |
1* | J:121833 Bonnin A, Torii M, Wang L, Rakic P, Levitt P, Serotonin modulates the response of embryonic thalamocortical axons to netrin-1. Nat Neurosci. 2007 May;10(5):588-97 |
1 | J:54722 Engelkamp D, Rashbass P, Seawright A, van Heyningen V, Role of Pax6 in development of the cerebellar system. Development. 1999 Aug;126(16):3585-96 |
1 | J:169455 Kim D, Ackerman SL, The UNC5C netrin receptor regulates dorsal guidance of mouse hindbrain axons. J Neurosci. 2011 Feb 9;31(6):2167-79 |
2* | J:278827 Murcia-Belmonte V, Coca Y, Vegar C, Negueruela S, de Juan Romero C, Valino AJ, Sala S, DaSilva R, Kania A, Borrell V, Martinez LM, Erskine L, Herrera E, A Retino-retinal Projection Guided by Unc5c Emerged in Species with Retinal Waves. Curr Biol. 2019 Apr 1;29(7):1149-1160.e4 |
1 | J:125013 Schmid T, Kruger M, Braun T, NSCL-1 and -2 control the formation of precerebellar nuclei by orchestrating the migration of neuronal precursor cells. J Neurochem. 2007 Sep;102(6):2061-72 |
1* | J:199400 van den Heuvel DM, Hellemons AJ, Pasterkamp RJ, Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain. PLoS One. 2013;8(2):e55828 |
1 | J:327333 Yang KY, Zhao S, Feng H, Shen J, Chen Y, Wang ST, Wang SJ, Zhang YX, Wang Y, Guo C, Liu H, Tang TS, Ca(2+) homeostasis maintained by TMCO1 underlies corpus callosum development via ERK signaling. Cell Death Dis. 2022 Aug 4;13(8):674 |
Unc5d unc-5 netrin receptor D (Synonyms: D930029E11Rik, Unc5h4) | |
Results | Reference |
2 | J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5 |
1 | J:219839 Hirota Y, Kubo K, Katayama K, Honda T, Fujino T, Yamamoto TT, Nakajima K, Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex. J Comp Neurol. 2015 Feb 15;523(3):463-78 |
1* | J:273015 Inoue S, Hayashi K, Fujita K, Tagawa K, Okazawa H, Kubo KI, Nakajima K, Drebrin-like (Dbnl) Controls Neuronal Migration via Regulating N-Cadherin Expression in the Developing Cerebral Cortex. J Neurosci. 2019 Jan 23;39(4):678-691 |
1* | J:297829 Li W, Shen W, Zhang B, Tian K, Li Y, Mu L, Luo Z, Zhong X, Wu X, Liu Y, Zhou Y, Long non-coding RNA LncKdm2b regulates cortical neuronal differentiation by cis-activating Kdm2b. Protein Cell. 2020 Mar;11(3):161-186 |
1 | J:150768 Okado H, Ohtaka-Maruyama C, Sugitani Y, Fukuda Y, Ishida R, Hirai S, Miwa A, Takahashi A, Aoki K, Mochida K, Suzuki O, Honda T, Nakajima K, Ogawa M, Terashima T, Matsuda J, Kawano H, Kasai M, The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Dev Biol. 2009 Jul 15;331(2):140-51 |
3 | J:141783 Sasaki S, Tabata H, Tachikawa K, Nakajima K, The cortical subventricular zone-specific molecule Svet1 is part of the nuclear RNA coded by the putative Netrin receptor gene Unc5d and is expressed in multipolar migrating cells. Mol Cell Neurosci. 2008 Aug;38(4):474-83 |
1* | J:186020 Takemoto M, Hattori Y, Zhao H, Sato H, Tamada A, Sasaki S, Nakajima K, Yamamoto N, Laminar and areal expression of unc5d and its role in cortical cell survival. Cereb Cortex. 2011 Aug;21(8):1925-34 |
1* | J:199400 van den Heuvel DM, Hellemons AJ, Pasterkamp RJ, Spatiotemporal expression of repulsive guidance molecules (RGMs) and their receptor neogenin in the mouse brain. PLoS One. 2013;8(2):e55828 |
Unc119b unc-119 lipid binding chaperone B | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Uncx UNC homeobox (Synonyms: Chx4, Uncx4.1) | |
Results | Reference |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
Unk unkempt family zinc finger (Synonyms: B230379M23Rik, mKIAA1753, Zc3h5) | |
Results | Reference |
1* | J:332849 Baskaran P, Mihaylov SR, Vinsland E, Shah K, Granat L, Ultanir SK, Tee AR, Murn J, Bateman JM, Phosphorylation of the novel mTOR substrate Unkempt regulates cellular morphogenesis. J Biol Chem. 2023 Jan;299(1):102788 |
2 | J:309451 Vinsland E, Baskaran P, Mihaylov SR, Hobbs C, Wood H, Bouybayoune I, Shah K, Houart C, Tee AR, Murn J, Fernandes C, Bateman JM, The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021 Aug 11;11(1):16299 |
Unkl unkempt family like zinc finger (Synonyms: 1300004G08Rik) | |
Results | Reference |
1 | J:309451 Vinsland E, Baskaran P, Mihaylov SR, Hobbs C, Wood H, Bouybayoune I, Shah K, Houart C, Tee AR, Murn J, Fernandes C, Bateman JM, The zinc finger/RING domain protein Unkempt regulates cognitive flexibility. Sci Rep. 2021 Aug 11;11(1):16299 |
Upf2 UPF2 regulator of nonsense transcripts homolog (yeast) | |
Results | Reference |
1 | J:163097 Thoren LA, Norgaard GA, Weischenfeldt J, Waage J, Jakobsen JS, Damgaard I, Bergstrom FC, Blom AM, Borup R, Bisgaard HC, Porse BT, UPF2 is a critical regulator of liver development, function and regeneration. PLoS One. 2010;5(7):e11650 |
Upk1a uroplakin 1A (Synonyms: 1110031P12Rik, Tspan21, Upk1) | |
Results | Reference |
2* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1* | J:250161 Lee AJ, Polgar N, Napoli JA, Lui VH, Tamashiro KK, Fujimoto BA, Thompson KS, Fogelgren B, Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy. Sci Rep. 2016 Aug 11;6:31137 |
1 | J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26 |
2* | J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903 |
Upk1b uroplakin 1B (Synonyms: Tspan20, Upk1) | |
Results | Reference |
2 | J:262819 Bohnenpoll T, Feraric S, Nattkemper M, Weiss AC, Rudat C, Meuser M, Trowe MO, Kispert A, Diversification of Cell Lineages in Ureter Development. J Am Soc Nephrol. 2017 Jun;28(6):1792-1801 |
1 | J:244068 Bohnenpoll T, Wittern AB, Mamo TM, Weiss AC, Rudat C, Kleppa MJ, Schuster-Gossler K, Wojahn I, Ludtke TH, Trowe MO, Kispert A, A SHH-FOXF1-BMP4 signaling axis regulating growth and differentiation of epithelial and mesenchymal tissues in ureter development. PLoS Genet. 2017 Aug;13(8):e1006951 |
1* | J:288446 Christians A, Weiss AC, Martens H, Klopf MG, Hennies I, Haffner D, Kispert A, Weber RG, Inflammation-like changes in the urothelium of Lifr-deficient mice and LIFR-haploinsufficient humans with urinary tract anomalies. Hum Mol Genet. 2020 May 8;29(7):1192-1204 |
1 | J:329048 Deuper L, Meuser M, Thiesler H, Jany UWH, Rudat C, Hildebrandt H, Trowe MO, Kispert A, Mesenchymal FGFR1 and FGFR2 control patterning of the ureteric mesenchyme by balancing SHH and BMP4 signaling. Development. 2022 Sep 1;149(17):dev200767 |
1 | J:327332 Kurz J, Weiss AC, Ludtke TH, Deuper L, Trowe MO, Thiesler H, Hildebrandt H, Heineke J, Duncan SA, Kispert A, GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter. Development. 2022 Aug 1;149(15):dev200522 |
1* | J:250161 Lee AJ, Polgar N, Napoli JA, Lui VH, Tamashiro KK, Fujimoto BA, Thompson KS, Fogelgren B, Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy. Sci Rep. 2016 Aug 11;6:31137 |
1 | J:243772 Mamo TM, Wittern AB, Kleppa MJ, Bohnenpoll T, Weiss AC, Kispert A, BMP4 uses several different effector pathways to regulate proliferation and differentiation in the epithelial and mesenchymal tissue compartments of the developing mouse ureter. Hum Mol Genet. 2017 Sep 15;26(18):3553-3563 |
1 | J:321503 Meuser M, Deuper L, Rudat C, Aydogdu N, Thiesler H, Zarnovican P, Hildebrandt H, Trowe MO, Kispert A, FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021 |
1* | J:118301 Patel S, Xi ZF, Seo EY, McGaughey D, Segre JA, Klf4 and corticosteroids activate an overlapping set of transcriptional targets to accelerate in utero epidermal barrier acquisition. Proc Natl Acad Sci U S A. 2006 Dec 5;103(49):18668-73 |
2* | J:326663 Qasrawi F, Meuser M, Lehnhoff F, Schulte M, Kispert A, S100A1 expression characterizes terminally differentiated superficial cells in the urothelium of the murine bladder and ureter. Histochem Cell Biol. 2022 Jun 1; |
1 | J:214811 Weiss AC, Airik R, Bohnenpoll T, Greulich F, Foik A, Trowe MO, Rudat C, Costantini F, Adams RH, Kispert A, Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme. Development. 2014 Sep;141(17):3420-30 |
1* | J:279388 Weiss AC, Bohnenpoll T, Kurz J, Blank P, Airik R, Ludtke TH, Kleppa MJ, Deuper L, Kaiser M, Mamo TM, Costa R, von Hahn T, Trowe MO, Kispert A, Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme. J Pathol. 2019 Aug;248(4):452-463 |
1 | J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26 |
1* | J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903 |
Upk2 uroplakin 2 (Synonyms: UPII, uroplakin II) | |
Results | Reference |
1* | J:250161 Lee AJ, Polgar N, Napoli JA, Lui VH, Tamashiro KK, Fujimoto BA, Thompson KS, Fogelgren B, Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy. Sci Rep. 2016 Aug 11;6:31137 |
2 | J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26 |
2* | J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903 |
Upk3a uroplakin 3A (Synonyms: 1110017C07Rik, Upk3) | |
Results | Reference |
1 | J:106499 Airik R, Bussen M, Singh MK, Petry M, Kispert A, Tbx18 regulates the development of the ureteral mesenchyme. J Clin Invest. 2006 Mar;116(3):663-74 |
1 | J:226950 Fogelgren B, Polgar N, Lui VH, Lee AJ, Tamashiro KK, Napoli JA, Walton CB, Zuo X, Lipschutz JH, Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions. PLoS One. 2015;10(6):e0129346 |
2 | J:188519 Guha A, Vasconcelos M, Cai Y, Yoneda M, Hinds A, Qian J, Li G, Dickel L, Johnson JE, Kimura S, Guo J, McMahon J, McMahon AP, Cardoso WV, Neuroepithelial body microenvironment is a niche for a distinct subset of Clara-like precursors in the developing airways. Proc Natl Acad Sci U S A. 2012 Jul 31;109(31):12592-7 |
1 | J:239161 Guo C, Balsara ZR, Hill WG, Li X, Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration. Development. 2017 Feb 01;144(3):400-408 |
1* | J:293098 Jafree DJ, Moulding D, Kolatsi-Joannou M, Perretta Tejedor N, Price KL, Milmoe NJ, Walsh CL, Correra RM, Winyard PJ, Harris PC, Ruhrberg C, Walker-Samuel S, Riley PR, Woolf AS, Scambler PJ, Long DA, Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease. Elife. 2019 Dec 6;8:e48183 |
1* | J:250161 Lee AJ, Polgar N, Napoli JA, Lui VH, Tamashiro KK, Fujimoto BA, Thompson KS, Fogelgren B, Fibroproliferative response to urothelial failure obliterates the ureter lumen in a mouse model of prenatal congenital obstructive nephropathy. Sci Rep. 2016 Aug 11;6:31137 |
1 | J:157941 Nie X, Sun J, Gordon RE, Cai CL, Xu PX, SIX1 acts synergistically with TBX18 in mediating ureteral smooth muscle formation. Development. 2010 Mar;137(5):755-65 |
1 | J:330441 Ortega MA, Villiger RK, Harrison-Chau M, Lieu S, Tamashiro KK, Lee AJ, Fujimoto BA, Patwardhan GY, Kepler J, Fogelgren B, Exocyst inactivation in urothelial cells disrupts autophagy and activates non-canonical NF-kappaB signaling. Dis Model Mech. 2022 Oct 1;15(10):dmm049785 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
1 | J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26 |
1 | J:187117 Xu J, Qi X, Gong J, Yu M, Zhang F, Sha H, Gao X, Fstl1 antagonizes BMP signaling and regulates ureter development. PLoS One. 2012;7(4):e32554 |
2* | J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903 |
Upk3b uroplakin 3B (Synonyms: P35, PMS2L14, UpIIIb) | |
Results | Reference |
1* | J:225159 Rudat C, Grieskamp T, Rohr C, Airik R, Wrede C, Hegermann J, Herrmann BG, Schuster-Gossler K, Kispert A, Upk3b is dispensable for development and integrity of urothelium and mesothelium. PLoS One. 2014;9(11):e112112 |
1 | J:315877 Tripathi P, Wang Y, Casey AM, Chen F, Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction. J Am Soc Nephrol. 2012 Apr;23(4):618-28 |
1 | J:210128 Weiss RM, Guo S, Shan A, Shi H, Romano RA, Sinha S, Cantley LG, Guo JK, Brg1 determines urothelial cell fate during ureter development. J Am Soc Nephrol. 2013 Mar;24(4):618-26 |
1* | J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903 |
Uqcc1 ubiquinol-cytochrome c reductase complex assembly factor 1 (Synonyms: 2310079L17Rik, 2410003P15Rik, 3110038N19Rik, Bfzp, Cbp3, mbFZb, Uqcc) | |
Results | Reference |
1* | J:66336 Vetter K, Wurst W, Expression of a novel mouse gene 'mbFZb' in distinct regions of the developing nervous system and the adult brain. Mech Dev. 2001 Jan;100(1):123-5 |
Uqcr10 ubiquinol-cytochrome c reductase, complex III subunit X (Synonyms: 1110020P15Rik) | |
Results | Reference |
1 | J:233841 Inoue M, Shima Y, Miyabayashi K, Tokunaga K, Sato T, Baba T, Ohkawa Y, Akiyama H, Suyama M, Morohashi K, Isolation and Characterization of Fetal Leydig Progenitor Cells of Male Mice. Endocrinology. 2016 Mar;157(3):1222-33 |
Uqcrc2 ubiquinol cytochrome c reductase core protein 2 (Synonyms: 1500004O06Rik) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
1 | J:337469 Park A, Kim KE, Park I, Lee SH, Park KY, Jung M, Li X, Sleiman MB, Lee SJ, Kim DS, Kim J, Lim DS, Woo EJ, Lee EW, Han BS, Oh KJ, Lee SC, Auwerx J, Mun JY, Rhee HW, Kim WK, Bae KH, Suh JM, Mitochondrial matrix protein LETMD1 maintains thermogenic capacity of brown adipose tissue in male mice. Nat Commun. 2023 Jun 23;14(1):3746 |
1* | J:305946 Xu M, Yao J, Shi Y, Yi H, Zhao W, Lin X, Yang Z, The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026 |
Uqcrq ubiquinol-cytochrome c reductase, complex III subunit VII (Synonyms: 1100001F06Rik, 1500040F11Rik, 5830407L17Rik, c1502, Qpc, QP-C) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
1* | J:333283 Guan N, Kobayashi H, Ishii K, Davidoff O, Sha F, Ikizler TA, Hao CM, Chandel NS, Haase VH, Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency. Kidney Int. 2022 Jul;102(1):108-120 |
Ush1c USH1 protein network component harmonin (Synonyms: 2010016F01Rik, harmonin, Usher syndrome 1C) | |
Results | Reference |
1 | J:80836 Boeda B, El-Amraoui A, Bahloul A, Goodyear R, Daviet L, Blanchard S, Perfettini I, Fath KR, Shorte S, Reiners J, Houdusse A, Legrain P, Wolfrum U, Richardson G, Petit C, Myosin VIIa, harmonin and cadherin 23, three Usher I gene products that cooperate to shape the sensory hair cell bundle. EMBO J. 2002 Dec 16;21(24):6689-99 |
1 | J:135991 Lefevre G, Michel V, Weil D, Lepelletier L, Bizard E, Wolfrum U, Hardelin JP, Petit C, A core cochlear phenotype in USH1 mouse mutants implicates fibrous links of the hair bundle in its cohesion, orientation and differential growth. Development. 2008 Apr;135(8):1427-37 |
Ush1g USH1 protein network component sans (Synonyms: js, Sans) | |
Results | Reference |
1 | J:171218 Caberlotto E, Michel V, Foucher I, Bahloul A, Goodyear RJ, Pepermans E, Michalski N, Perfettini I, Alegria-Prevot O, Chardenoux S, Do Cruzeiro M, Hardelin JP, Richardson GP, Avan P, Weil D, Petit C, Usher type 1G protein sans is a critical component of the tip-link complex, a structure controlling actin polymerization in stereocilia. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5825-30 |
Usp2 ubiquitin specific peptidase 2 (Synonyms: B930035K21Rik, ubp41) | |
Results | Reference |
1* | J:108694 Gousseva N, Baker RT, Gene structure, alternate splicing, tissue distribution, cellular localization, and developmental expression pattern of mouse deubiquitinating enzyme isoforms Usp2-45 and Usp2-69. Gene Expr. 2003;11(3-4):163-79 |
Usp8 ubiquitin specific peptidase 8 (Synonyms: mKIAA0055, Ubpy) | |
Results | Reference |
2* | J:165158 d'Amora M, Angelini C, Aluigi MG, Marcoli M, Maura G, Berruti G, Vallarino M, Expression pattern of mUBPy in the brain and sensory organs of mouse during embryonic development. Brain Res. 2010 Oct 8;1355:16-30 |
Usp12 ubiquitin specific peptidase 12 (Synonyms: Ubh1) | |
Results | Reference |
1 | J:47937 Hansen-Hagge TE, Janssen JW, Hameister H, Papa FR, Zechner U , Seriu T , Jauch A , Becke D , Hochstrasser M , Bartram CR, An evolutionarily conserved gene on human chromosome 5q33-q34, UBH1, encodes a novel deubiquitinating enzyme. Genomics. 1998 May 1;49(3):411-8 |
Usp15 ubiquitin specific peptidase 15 (Synonyms: 4921514G19Rik, E430033I05Rik, Gcap18, mKIAA0529) | |
Results | Reference |
1 | J:348286 Zhang Z, Wu Y, Fu J, Yu X, Su Y, Jia S, Cheng H, Shen Y, He X, Ren K, Zheng X, Guan H, Rao F, Zhao L, Proteostatic reactivation of the developmental transcription factor TBX3 drives BRAF/MAPK-mediated tumorigenesis. Nat Commun. 2024 May 15;15(1):4108 |
Usp22 ubiquitin specific peptidase 22 | |
Results | Reference |
1* | J:105884 Lee HJ, Kim MS, Shin JM, Park TJ, Chung HM, Baek KH, The expression patterns of deubiquitinating enzymes, USP22 and Usp22. Gene Expr Patterns. 2006 Mar;6(3):277-84 |
Usp25 ubiquitin specific peptidase 25 | |
Results | Reference |
1 | J:60249 Valero R, Marfany G, Gonzalez-Angulo O, Gonzalez-Gonzalez G, Puelles L, Gonzalez-Duarte R, USP25, a novel gene encoding a deubiquitinating enzyme, is located in the gene-poor region 21q11.2. Genomics. 1999 Dec 15;62(3):395-405 |
1* | J:259125 Yang J, Hung LH, Licht T, Kostin S, Looso M, Khrameeva E, Bindereif A, Schneider A, Braun T, RBM24 is a major regulator of muscle-specific alternative splicing. Dev Cell. 2014 Oct 13;31(1):87-99 |
Usp28 ubiquitin specific peptidase 28 (Synonyms: 9830148O20Rik, mKIAA1515) | |
Results | Reference |
1* | J:259125 Yang J, Hung LH, Licht T, Kostin S, Looso M, Khrameeva E, Bindereif A, Schneider A, Braun T, RBM24 is a major regulator of muscle-specific alternative splicing. Dev Cell. 2014 Oct 13;31(1):87-99 |
Usp42 ubiquitin specific peptidase 42 (Synonyms: 2410140K03Rik, 3110031A07Rik, A630018G05Rik, D5Ertd591e) | |
Results | Reference |
1* | J:116001 Kim YK, Kim YS, Yoo KJ, Lee HJ, Lee DR, Yeo CY, Baek KH, The expression of Usp42 during embryogenesis and spermatogenesis in mouse. Gene Expr Patterns. 2007 Jan;7(1-2):143-8 |
Utp18 UTP18 small subunit processome component (Synonyms: 6230425C22Rik, Wdr50) | |
Results | Reference |
1* | J:164279 Trivedi CM, Zhu W, Wang Q, Jia C, Kee HJ, Li L, Hannenhalli S, Epstein JA, Hopx and Hdac2 interact to modulate Gata4 acetylation and embryonic cardiac myocyte proliferation. Dev Cell. 2010 Sep 14;19(3):450-9 |
Utp25 UTP25 small subunit processome component (Synonyms: AA408296, Diexf, mDef) | |
Results | Reference |
1 | J:309161 Huang W, Chen F, Ma Q, Xin J, Li J, Chen J, Zhou B, Chen M, Li J, Peng J, Ribosome biogenesis gene DEF/UTP25 is essential for liver homeostasis and regeneration. Sci China Life Sci. 2020 Nov;63(11):1651-1664 |
Utrn utrophin (Synonyms: Dmdl, DRP, G-utrophin) | |
Results | Reference |
2 | J:334506 Gleneadie HJ, Fernandez-Ruiz B, Sardini A, Van de Pette M, Dimond A, Prinjha RK, McGinty J, French PMW, Bagci H, Merkenschlager M, Fisher AG, Endogenous bioluminescent reporters reveal a sustained increase in utrophin gene expression upon EZH2 and ERK1/2 inhibition. Commun Biol. 2023 Mar 25;6(1):318 |
2 | J:81455 Jimenez-Mallebrera C, Davies K, Putt W, Edwards YH, A study of short utrophin isoforms in mice deficient for full-length utrophin. Mamm Genome. 2003 Jan;14(1):47-60 |
Uty ubiquitously transcribed tetratricopeptide repeat containing, Y-linked (Synonyms: Hydb) | |
Results | Reference |
1 | J:205146 Praktiknjo SD, Llamas B, Scott-Boyer MP, Picard S, Robert F, Langlais D, Haibe-Kains B, Faubert D, Silversides DW, Deschepper CF, Novel effects of chromosome Y on cardiac regulation, chromatin remodeling, and neonatal programming in male mice. Endocrinology. 2013 Dec;154(12):4746-56 |
Uxt ubiquitously expressed prefoldin like chaperone (Synonyms: 0910002B17Rik) | |
Results | Reference |
1 | J:303303 Pan M, Yin Y, Wang X, Wang Q, Zhang L, Hu H, Wang C, Mice deficient in UXT exhibit retinitis pigmentosa-like features via aberrant autophagy activation. Autophagy. 2020 Aug 2;:1-16 |
Vamp2 vesicle-associated membrane protein 2 (Synonyms: Syb-2, Syb2, sybII, synaptobrevin-2, synaptobrevin II) | |
Results | Reference |
1 | J:284900 Larsen R, Proue A, Scott EP, Christiansen M, Nakagawa Y, The Thalamus Regulates Retinoic Acid Signaling and Development of Parvalbumin Interneurons in Postnatal Mouse Prefrontal Cortex. eNeuro. 2019 Jan-Feb;6(1):ENEURO.0018-19.2019 |
Vamp7 vesicle-associated membrane protein 7 (Synonyms: Sybl1, VAMP-7) | |
Results | Reference |
1 | J:226885 Tannour-Louet M, Han S, Louet JF, Zhang B, Romero K, Addai J, Sahin A, Cheung SW, Lamb DJ, Increased gene copy number of VAMP7 disrupts human male urogenital development through altered estrogen action. Nat Med. 2014 Jul;20(7):715-24 |
Vangl2 VANGL planar cell polarity 2
(Synonyms:
C530001F03Rik, loop-tail, Lootl, Lpp1, Ltap, mKIAA1215, ska17, ska | |
Results | Reference |
1* | J:168261 Babayeva S, Zilber Y, Torban E, Planar cell polarity pathway regulates actin rearrangement, cell shape, motility, and nephrin distribution in podocytes. Am J Physiol Renal Physiol. 2011 Feb;300(2):F549-60 |
1 | J:212241 Boutin C, Labedan P, Dimidschstein J, Richard F, Cremer H, Andre P, Yang Y, Montcouquiol M, Goffinet AM, Tissir F, A dual role for planar cell polarity genes in ciliated cells. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):E3129-38 |
1 | J:264107 Ghimire SR, Ratzan EM, Deans MR, A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea. Development. 2018 Jun 14;145(12):dev159012 |
2* | J:169664 Guyot MC, Bosoi CM, Kharfallah F, Reynolds A, Drapeau P, Justice M, Gros P, Kibar Z, A novel hypomorphic Looptail allele at the planar cell polarity Vangl2 gene. Dev Dyn. 2011 Apr;240(4):839-49 |
1 | J:216288 Jones C, Qian D, Kim SM, Li S, Ren D, Knapp L, Sprinzak D, Avraham KB, Matsuzaki F, Chi F, Chen P, Ankrd6 is a mammalian functional homolog of Drosophila planar cell polarity gene diego and regulates coordinated cellular orientation in the mouse inner ear. Dev Biol. 2014 Nov 1;395(1):62-72 |
1 | J:273200 Landin Malt A, Dailey Z, Holbrook-Rasmussen J, Zheng Y, Hogan A, Du Q, Lu X, Par3 is essential for the establishment of planar cell polarity of inner ear hair cells. Proc Natl Acad Sci U S A. 2019 Mar 12;116(11):4999-5008 |
1 | J:83127 Montcouquiol M, Rachel RA, Lanford PJ, Copeland NG, Jenkins NA, Kelley MW, Identification of Vangl2 and Scrb1 as planar polarity genes in mammals. Nature. 2003 May 8;423(6936):173-7 |
2* | J:72911 Murdoch JN, Doudney K, Paternotte C, Copp AJ, Stanier P, Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification. Hum Mol Genet. 2001 Oct 15;10(22):2593-601 |
1 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1* | J:116150 Torban E, Wang HJ, Patenaude AM, Riccomagno M, Daniels E, Epstein D, Gros P, Tissue, cellular and sub-cellular localization of the Vangl2 protein during embryonic development: Effect of the Lp mutation. Gene Expr Patterns. 2007 Jan;7(3):346-54 |
1 | J:314898 Wu Z, Epasinghe DJ, He J, Li L, Green DW, Lee MJ, Jung HS, Altered tooth morphogenesis after silencing the planar cell polarity core component, Vangl2. Cell Tissue Res. 2016 Dec;366(3):617-621 |
Vav3 vav 3 oncogene (Synonyms: A530094I06Rik, Idd18.1) | |
Results | Reference |
1 | J:154739 Quina LA, Wang S, Ng L, Turner EE, Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci. 2009 Nov 11;29(45):14309-22 |
Vax1 ventral anterior homeobox 1 | |
Results | Reference |
1 | J:58996 Bertuzzi S, Hindges R, Mui SH, O'Leary DD, Lemke G, The homeodomain protein vax1 is required for axon guidance and major tract formation in the developing forebrain. Genes Dev. 1999 Dec 1;13(23):3092-105 |
1 | J:292487 Guo T, Liu G, Du H, Wen Y, Wei S, Li Z, Tao G, Shang Z, Song X, Zhang Z, Xu Z, You Y, Chen B, Rubenstein JL, Yang Z, Dlx1/2 are Central and Essential Components in the Transcriptional Code for Generating Olfactory Bulb Interneurons. Cereb Cortex. 2019 Dec 17;29(11):4831-4849 |
1 | J:113403 Kim JW, Lemke G, Hedgehog-regulated localization of Vax2 controls eye development. Genes Dev. 2006 Oct 15;20(20):2833-47 |
1 | J:264268 Li J, Wang C, Zhang Z, Wen Y, An L, Liang Q, Xu Z, Wei S, Li W, Guo T, Liu G, Tao G, You Y, Du H, Fu Z, He M, Chen B, Campbell K, Alvarez-Buylla A, Rubenstein JL, Yang Z, Transcription Factors Sp8 and Sp9 Coordinately Regulate Olfactory Bulb Interneuron Development. Cereb Cortex. 2018 Sep 1;28(9):3278-3294 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:341676 Wen Y, Su Z, Wang Z, Yang L, Liu G, Shang Z, Duan Y, Du H, Li Z, You Y, Li X, Yang Z, Zhang Z, Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2. Mol Neurobiol. 2021 Aug;58(8):3729-3744 |
Vax2 ventral anterior homeobox 2 | |
Results | Reference |
1* | J:57663 Barbieri AM, Lupo G, Bulfone A, Andreazzoli M, Mariani M, Fougerousse F, Consalez GG, Borsani G, Beckmann JS, Barsacchi G, Ballabio A, Banfi S, A homeobox gene, vax2, controls the patterning of the eye dorsoventral axis. Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10729-34 |
2 | J:113403 Kim JW, Lemke G, Hedgehog-regulated localization of Vax2 controls eye development. Genes Dev. 2006 Oct 15;20(20):2833-47 |
1* | J:316715 Meola N, Pizzo M, Alfano G, Surace EM, Banfi S, The long noncoding RNA Vax2os1 controls the cell cycle progression of photoreceptor progenitors in the mouse retina. RNA. 2012 Jan;18(1):111-23 |
1 | J:333797 Min KW, Kim N, Lee JH, Sung Y, Kim M, Lee EJ, Kim JM, Kim JH, Lee J, Cho W, Yang JM, Kim N, Kim J, Lee CJ, Park YG, Lee SH, Lee HW, Kim JW, Visuomotor anomalies in achiasmatic mice expressing a transfer-defective Vax1 mutant. Exp Mol Med. 2023 Feb;55(2):385-400 |
1* | J:328043 Ohsaki K, Morimitsu T, Ishida Y, Kominami R, Takahashi N, Expression of the Vax family homeobox genes suggests multiple roles in eye development. Genes Cells. 1999 May;4(5):267-76 |
Vax2os ventral anterior homeobox 2, opposite strand (Synonyms: Vax2os1, Vax2os2) | |
Results | Reference |
1* | J:98077 Alfano G, Vitiello C, Caccioppoli C, Caramico T, Carola A, Szego MJ, McInnes RR, Auricchio A, Banfi S, Natural antisense transcripts associated with genes involved in eye development. Hum Mol Genet. 2005 Apr 1;14(7):913-23 |
2* | J:316715 Meola N, Pizzo M, Alfano G, Surace EM, Banfi S, The long noncoding RNA Vax2os1 controls the cell cycle progression of photoreceptor progenitors in the mouse retina. RNA. 2012 Jan;18(1):111-23 |
Vcam1 vascular cell adhesion molecule 1 (Synonyms: CD106, Vcam-1) | |
Results | Reference |
1 | J:45633 Adachi S, Yoshida H, Honda K, Maki K, Saijo K, Ikuta K, Saito T, Nishikawa SI, Essential role of IL-7 receptor alpha in the formation of Peyer's patch anlage. Int Immunol. 1998 Jan;10(1):1-6 |
1 | J:301331 Bridges JP, Sudha P, Lipps D, Wagner A, Guo M, Du Y, Brown K, Filuta A, Kitzmiller J, Stockman C, Chen X, Weirauch MT, Jobe AH, Whitsett JA, Xu Y, Glucocorticoid regulates mesenchymal cell differentiation required for perinatal lung morphogenesis and function. Am J Physiol Lung Cell Mol Physiol. 2020 Aug 1;319(2):L239-L255 |
1 | J:188796 de Lau W, Kujala P, Schneeberger K, Middendorp S, Li VS, Barker N, Martens A, Hofhuis F, DeKoter RP, Peters PJ, Nieuwenhuis E, Clevers H, Peyer's patch M cells derived from Lgr5(+) stem cells require SpiB and are induced by RankL in cultured "miniguts". Mol Cell Biol. 2012 Sep;32(18):3639-47 |
1 | J:87395 Eberl G, Marmon S, Sunshine MJ, Rennert PD, Choi Y, Littman DR, An essential function for the nuclear receptor RORgamma(t) in the generation of fetal lymphoid tissue inducer cells. Nat Immunol. 2004 Jan;5(1):64-73 |
1* | J:67917 Honda K, Nakano H, Yoshida H, Nishikawa S, Rennert P, Ikuta K, Tamechika M, Yamaguchi K, Fukumoto T, Chiba T, Nishikawa SI, Molecular basis for hematopoietic/mesenchymal interaction during initiation of peyer's patch organogenesis. J Exp Med. 2001 Mar 5;193(5):621-30 |
1 | J:253242 Hu XL, Chen G, Zhang S, Zheng J, Wu J, Bai QR, Wang Y, Li J, Wang H, Feng H, Li J, Sun X, Xia Q, Yang F, Hang J, Qi C, Phoenix TN, Temple S, Shen Q, Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells. Neuron. 2017 Jul 19;95(2):309-325.e6 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1 | J:123554 Meier D, Bornmann C, Chappaz S, Schmutz S, Otten LA, Ceredig R, Acha-Orbea H, Finke D, Ectopic lymphoid-organ development occurs through interleukin 7-mediated enhanced survival of lymphoid-tissue-inducer cells. Immunity. 2007 May;26(5):643-54 |
1* | J:115860 Tada T, Widayati DT, Fukuta K, Morphological study of the transition of haematopoietic sites in the developing mouse during the peri-natal period. Anat Histol Embryol. 2006 Aug;35(4):235-40 |
1* | J:22984 Venuti JM, Morris JH, Vivian JL, Olson EN, Klein WH, Myogenin is required for late but not early aspects of myogenesis during mouse development. J Cell Biol. 1995 Feb;128(4):563-76 |
1 | J:137812 Vondenhoff MF, Desanti GE, Cupedo T, Bertrand JY, Cumano A, Kraal G, Mebius RE, Golub R, Separation of splenic red and white pulp occurs before birth in a LTalphabeta-independent manner. J Leukoc Biol. 2008 Jul;84(1):152-61 |
1 | J:150308 Vondenhoff MF, Greuter M, Goverse G, Elewaut D, Dewint P, Ware CF, Hoorweg K, Kraal G, Mebius RE, LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen. J Immunol. 2009 May 1;182(9):5439-45 |
1 | J:251156 Wen Q, Wang Y, Tang J, Cheng CY, Liu YX, Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development. PLoS One. 2016;11(12):e0167920 |
1 | J:241335 Yang Y, Enis D, Zheng H, Chia S, Yang J, Chen M, Dhillon V, Papayannapoulou T, Kahn ML, Cell Adhesion Mediated by VCAM-ITGalpha9 Interactions Enables Lymphatic Development. Arterioscler Thromb Vasc Biol. 2015 May;35(5):1179-89 |
Vcan versican (Synonyms: 5430420N07Rik, Cspg2, DPEAAE, hdf, heart defect, PG-M) | |
Results | Reference |
1 | J:226941 Akerberg BN, Sarangam ML, Stankunas K, Endocardial Brg1 disruption illustrates the developmental origins of semilunar valve disease. Dev Biol. 2015 Nov 1;407(1):158-72 |
1* | J:316301 Asano K, Nelson CM, Nandadasa S, Aramaki-Hattori N, Lindner DJ, Alban T, Inagaki J, Ohtsuki T, Oohashi T, Apte SS, Hirohata S, Stromal Versican Regulates Tumor Growth by Promoting Angiogenesis. Sci Rep. 2017 Dec 8;7(1):17225 |
1 | J:335626 Castillo V, Diaz-Astudillo P, Corrales-Orovio R, San Martin S, Egana JT, Comprehensive Characterization of Tissues Derived from Animals at Different Regenerative Stages: A Comparative Analysis between Fetal and Adult Mouse Skin. Cells. 2023 Apr 22;12(9) |
2 | J:179734 Cooley MA, Fresco VM, Dorlon ME, Twal WO, Lee NV, Barth JL, Kern CB, Iruela-Arispe ML, Argraves WS, Fibulin-1 is required during cardiac ventricular morphogenesis for versican cleavage, suppression of ErbB2 and Erk1/2 activation, and to attenuate trabecular cardiomyocyte proliferation. Dev Dyn. 2012 Feb;241(2):303-14 |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:185218 Hall-Glenn F, De Young RA, Huang BL, van Handel B, Hofmann JJ, Chen TT, Choi A, Ong JR, Benya PD, Mikkola H, Iruela-Arispe ML, Lyons KM, CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PLoS One. 2012;7(2):e30562 |
1 | J:121090 Ito Y, Hamazaki TS, Ohnuma K, Tamaki K, Asashima M, Okochi H, Isolation of murine hair-inducing cells using the cell surface marker prominin-1/CD133. J Invest Dermatol. 2007 May;127(5):1052-60 |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
2 | J:81588 Kaplan F, Comber J, Sladek R, Hudson TJ, Muglia LJ, Macrae T, Gagnon S, Asada M, Brewer JA, Sweezey NB, The growth factor midkine is modulated by both glucocorticoid and retinoid in fetal lung development. Am J Respir Cell Mol Biol. 2003 Jan;28(1):33-41 |
2* | J:119223 Kern CB, Twal WO, Mjaatvedt CH, Fairey SE, Toole BP, Iruela-Arispe ML, Argraves WS, Proteolytic cleavage of versican during cardiac cushion morphogenesis. Dev Dyn. 2006 Aug;235(8):2238-47 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1* | J:148803 McCulloch DR, Le Goff C, Bhatt S, Dixon LJ, Sandy JD, Apte SS, Adamts5, the gene encoding a proteoglycan-degrading metalloprotease, is expressed by specific cell lineages during mouse embryonic development and in adult tissues. Gene Expr Patterns. 2009 Jun;9(5):314-23 |
1 | J:155754 McCulloch DR, Nelson CM, Dixon LJ, Silver DL, Wylie JD, Lindner V, Sasaki T, Cooley MA, Argraves WS, Apte SS, ADAMTS metalloproteases generate active versican fragments that regulate interdigital web regression. Dev Cell. 2009 Nov;17(5):687-98 |
1 | J:348792 Mead TJ, Bhutada S, Foulcer SJ, Peruzzi N, Nelson CM, Seifert DE, Larkin J, Tran-Lundmark K, Filmus J, Apte SS, Combined genetic-pharmacologic inactivation of tightly linked ADAMTS proteases in temporally specific windows uncovers distinct roles for versican proteolysis and glypican-6 in cardiac development. Matrix Biol. 2024 May 13; |
1 | J:50400 Rice DS, Sheldon M, D'Arcangelo G, Nakajima K, Goldowitz D, Curran T, Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain. Development. 1998 Sep;125(18):3719-29 |
2* | J:277788 Xu F, Cai W, Chen W, Li L, Li X, Jiang B, Expression of Different Isoforms of Versican During the Development of Mouse Mandibular First Molars. J Histochem Cytochem. 2019 Jul;67(7):471-480 |
Vcl vinculin (Synonyms: metavinculin) | |
Results | Reference |
1 | J:331894 Alcantara MC, Suzuki K, Acebedo AR, Kajioka D, Hirohata S, Kaisho T, Hatano Y, Yamagata K, Takahashi S, Yamada G, Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice. iScience. 2022 Dec 22;25(12):105609 |
1 | J:308827 Kaiser K, Jang A, Kompanikova P, Lun MP, Prochazka J, Machon O, Dani N, Prochazkova M, Laurent B, Gyllborg D, van Amerongen R, Fame RM, Gupta S, Wu F, Barker RA, Bukova I, Sedlacek R, Kozmik Z, Arenas E, Lehtinen MK, Bryja V, MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus. Development. 2021 May 15;148(10):dev192054 |
1 | J:199510 Lee J, Andreeva A, Sipe CW, Liu L, Cheng A, Lu X, PTK7 regulates myosin II activity to orient planar polarity in the mammalian auditory epithelium. Curr Biol. 2012 Jun 5;22(11):956-66 |
1 | J:294113 Lough KJ, Byrd KM, Descovich CP, Spitzer DC, Bergman AJ, Beaudoin GM 3rd, Reichardt LF, Williams SE, Telophase correction refines division orientation in stratified epithelia. Elife. 2019 Dec 13;8:e49249 |
2 | J:256217 Rubsam M, Mertz AF, Kubo A, Marg S, Jungst C, Goranci-Buzhala G, Schauss AC, Horsley V, Dufresne ER, Moser M, Ziegler W, Amagai M, Wickstrom SA, Niessen CM, E-cadherin integrates mechanotransduction and EGFR signaling to control junctional tissue polarization and tight junction positioning. Nat Commun. 2017 Nov 1;8(1):1250 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1 | J:187673 Zhang J, Neal J, Lian G, Shi B, Ferland RJ, Sheen V, Brefeldin A-inhibited Guanine Exchange Factor 2 Regulates Filamin A Phosphorylation and Neuronal Migration. J Neurosci. 2012 Sep 5;32(36):12619-29 |
Vdac1 voltage-dependent anion channel 1 (Synonyms: Vdac5) | |
Results | Reference |
1 | J:345617 Beutner G, Burris JR, Collins MP, Kulkarni CA, Nadtochiy SM, de Mesy Bentley KL, Cohen ED, Brookes PS, Porter GA Jr, Coordinated metabolic responses to cyclophilin D deletion in the developing heart. iScience. 2024 Mar 15;27(3):109157 |
Vdr vitamin D (1,25-dihydroxyvitamin D3) receptor (Synonyms: Nr1i1) | |
Results | Reference |
2 | J:133064 Brancaz-Bouvier MV, Folco EJ, Salameire D, Romero Y, Iratni R, Nonchev S, The 'bald Mill Hill' mutation in the mouse is associated with an abnormal, mislocalized HR bmh protein. J Invest Dermatol. 2008 Feb;128(2):311-21 |
1 | J:356109 Ge W, Tan SJ, Wang SH, Li L, Sun XF, Shen W, Wang X, Single-cell Transcriptome Profiling reveals Dermal and Epithelial cell fate decisions during Embryonic Hair Follicle Development. Theranostics. 2020;10(17):7581-7598 |
2* | J:42054 Yoshizawa T, Handa Y, Uematsu Y, Takeda S, Sekine K, Yoshihara Y , Kawakami T , Arioka K , Sato H , Uchiyama Y , Masushige S , Fukamizu A , Matsumoto T , Kato S, Mice lacking the vitamin D receptor exhibit impaired bone formation, uterine hypoplasia and growth retardation after weaning. Nat Genet. 1997 Aug;16(4):391-6 |
Vegfa vascular endothelial growth factor A (Synonyms: Vegf, VEGF120, VEGF164, VEGF188, VEGF-A, VPF) | |
Results | Reference |
1* | J:305967 Abid MR, Yi X, Yano K, Shih SC, Aird WC, Vascular endocan is preferentially expressed in tumor endothelium. Microvasc Res. 2006 Nov;72(3):136-45 |
1 | J:310856 Almubarak A, Lavy R, Srnic N, Hu Y, Maripuri DP, Kume T, Berry FB, Loss of Foxc1 and Foxc2 function in chondroprogenitor cells disrupts endochondral ossification. J Biol Chem. 2021 Jul 29;297(3):101020 |
1 | J:353623 Almubarak A, Zhang Q, Zhang CH, Abdelwahab N, Kume T, Lassar AB, Berry FB, FOXC1 and FOXC2 regulate growth plate chondrocyte maturation towards hypertrophy in the embryonic mouse limb skeleton. Development. 2024 Aug 15;151(16) |
1 | J:97179 Colnot C, de la Fuente L, Huang S, Hu D, Lu C, St-Jacques B, Helms JA, Indian hedgehog synchronizes skeletal angiogenesis and perichondrial maturation with cartilage development. Development. 2005 Mar;132(5):1057-67 |
1 | J:77480 Compernolle V, Brusselmans K, Acker T, Hoet P, Tjwa M, Beck H, Plaisance S, Dor Y, Keshet E, Lupu F, Nemery B, Dewerchin M, Van Veldhoven P, Plate K, Moons L, Collen D, Carmeliet P, Loss of HIF-2alpha and inhibition of VEGF impair fetal lung maturation, whereas treatment with VEGF prevents fatal respiratory distress in premature mice. Nat Med. 2002 Jul;8(7):702-10 |
1 | J:311143 Courtney JA, Wilson RL, Cnota J, Jones HN, Conditional Mutation of Hand1 in the Mouse Placenta Disrupts Placental Vascular Development Resulting in Fetal Loss in Both Early and Late Pregnancy. Int J Mol Sci. 2021 Sep 2;22(17) |
1 | J:262042 Del Monte-Nieto G, Ramialison M, Adam AAS, Wu B, Aharonov A, D'Uva G, Bourke LM, Pitulescu ME, Chen H, de la Pompa JL, Shou W, Adams RH, Harten SK, Tzahor E, Zhou B, Harvey RP, Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation. Nature. 2018 May;557(7705):439-445 |
1 | J:237001 Duan X, Bradbury SR, Olsen BR, Berendsen AD, VEGF stimulates intramembranous bone formation during craniofacial skeletal development. Matrix Biol. 2016 May-Jul;52-54:127-40 |
1 | J:347133 Funato N, Srivastava D, Shibata S, Yanagisawa H, TBX1 Regulates Chondrocyte Maturation in the Spheno-occipital Synchondrosis. J Dent Res. 2020 Sep;99(10):1182-1191 |
1 | J:185118 Galli GG, Honnens de Lichtenberg K, Carrara M, Hans W, Wuelling M, Mentz B, Multhaupt HA, Fog CK, Jensen KT, Rappsilber J, Vortkamp A, Coulton L, Fuchs H, Gailus-Durner V, Hrabe de Angelis M, Calogero RA, Couchman JR, Lund AH, Prdm5 regulates collagen gene transcription by association with RNA polymerase II in developing bone. PLoS Genet. 2012 May;8(5):e1002711 |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1 | J:264149 Goto S, Onishi A, Misaki K, Yonemura S, Sugita S, Ito H, Ohigashi Y, Ema M, Sakaguchi H, Nishida K, Takahashi M, Neural retina-specific Aldh1a1 controls dorsal choroidal vascular development via Sox9 expression in retinal pigment epithelial cells. Elife. 2018 Apr 3;7:e32358 |
3 | J:76918 Greenberg JM, Thompson FY, Brooks SK, Shannon JM, McCormick-Shannon K, Cameron JE, Mallory BP, Akeson AL, Mesenchymal expression of vascular endothelial growth factors D and A defines vascular patterning in developing lung. Dev Dyn. 2002 Jun;224(2):144-53 |
1 | J:185218 Hall-Glenn F, De Young RA, Huang BL, van Handel B, Hofmann JJ, Chen TT, Choi A, Ong JR, Benya PD, Mikkola H, Iruela-Arispe ML, Lyons KM, CCN2/connective tissue growth factor is essential for pericyte adhesion and endothelial basement membrane formation during angiogenesis. PLoS One. 2012;7(2):e30562 |
1 | J:159025 Hattori T, Muller C, Gebhard S, Bauer E, Pausch F, Schlund B, Bosl MR, Hess A, Surmann-Schmitt C, von der Mark H, de Crombrugghe B, von der Mark K, SOX9 is a major negative regulator of cartilage vascularization, bone marrow formation and endochondral ossification. Development. 2010 Mar;137(6):901-11 |
1* | J:78912 Hellstrom M, Gerhardt H, Kalen M, Li X, Eriksson U, Wolburg H, Betsholtz C, Lack of pericytes leads to endothelial hyperplasia and abnormal vascular morphogenesis. J Cell Biol. 2001 Apr 30;153(3):543-53 |
1 | J:200722 Hick AC, Delmarcelle AS, Bouquet M, Klotz S, Copetti T, Forez C, Van Der Smissen P, Sonveaux P, Collet JF, Feron O, Courtoy PJ, Pierreux CE, Reciprocal epithelial:endothelial paracrine interactions during thyroid development govern follicular organization and C-cells differentiation. Dev Biol. 2013 Sep 1;381(1):227-40 |
1 | J:309228 Hill C, Jacobs B, Kennedy L, Rohde S, Zhou B, Baldwin S, Goudy S, Cranial neural crest deletion of VEGFa causes cleft palate with aberrant vascular and bone development. Cell Tissue Res. 2015 Sep;361(3):711-22 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:122952 Hung IH, Yu K, Lavine KJ, Ornitz DM, FGF9 regulates early hypertrophic chondrocyte differentiation and skeletal vascularization in the developing stylopod. Dev Biol. 2007 Jul 15;307(2):300-13 |
1 | J:188305 Ishijima M, Suzuki N, Hozumi K, Matsunobu T, Kosaki K, Kaneko H, Hassell JR, Arikawa-Hirasawa E, Yamada Y, Perlecan modulates VEGF signaling and is essential for vascularization in endochondral bone formation. Matrix Biol. 2012 May;31(4):234-45 |
1 | J:199291 Jiang M, Ku WY, Fu J, Offermanns S, Hsu W, Que J, Gpr177 regulates pulmonary vasculature development. Development. 2013 Sep;140(17):3589-94 |
1* | J:331874 Lee H, Kim DW, Deletion of ATAD3A inhibits osteogenesis by impairing mitochondria structure and function in pre-osteoblast. Dev Dyn. 2022 Dec;251(12):1982-2000 |
1 | J:119882 Liu Z, Lavine KJ, Hung IH, Ornitz DM, FGF18 is required for early chondrocyte proliferation, hypertrophy and vascular invasion of the growth plate. Dev Biol. 2007 Feb 1;302(1):80-91 |
2* | J:231234 Luna RL, Kay VR, Ratsep MT, Khalaj K, Bidarimath M, Peterson N, Carmeliet P, Jin A, Croy BA, Placental growth factor deficiency is associated with impaired cerebral vascular development in mice. Mol Hum Reprod. 2016 Feb;22(2):130-42 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1* | J:93152 Maclean HE, Kronenberg HM, Expression of Stra13 during mouse endochondral bone development. Gene Expr Patterns. 2004 Oct;4(6):633-6 |
2 | J:233282 Maes C, Araldi E, Haigh K, Khatri R, Van Looveren R, Giaccia AJ, Haigh JJ, Carmeliet G, Schipani E, VEGF-independent cell-autonomous functions of HIF-1alpha regulating oxygen consumption in fetal cartilage are critical for chondrocyte survival. J Bone Miner Res. 2012 Mar;27(3):596-609 |
1* | J:74493 Maes C, Carmeliet P, Moermans K, Stockmans I, Smets N, Collen D, Bouillon R, Carmeliet G, Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF(164) and VEGF(188). Mech Dev. 2002 Feb;111(1-2):61-73 |
1 | J:87618 Maes C, Stockmans I, Moermans K, Van Looveren R, Smets N, Carmeliet P, Bouillon R, Carmeliet G, Soluble VEGF isoforms are essential for establishing epiphyseal vascularization and regulating chondrocyte development and survival. J Clin Invest. 2004 Jan;113(2):188-99 |
1* | J:67157 McCright B, Gao X, Shen L, Lozier J, Lan Y, Maguire M, Herzlinger D, Weinmaster G, Jiang R, Gridley T, Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development. 2001 Feb;128(4):491-502 |
2 | J:214759 McKenna CC, Ojeda AF, Spurlin J 3rd, Kwiatkowski S, Lwigale PY, Sema3A maintains corneal avascularity during development by inhibiting Vegf induced angioblast migration. Dev Biol. 2014 Jul 15;391(2):241-50 |
1 | J:310900 Mesnieres M, Bohm AM, Peredo N, Trompet D, Valle-Tenney R, Bajaj M, Corthout N, Nefyodova E, Cardoen R, Baatsen P, Munck S, Nagy A, Haigh JJ, Khurana S, Verfaillie CM, Maes C, Fetal hematopoietic stem cell homing is controlled by VEGF regulating the integrity and oxidative status of the stromal-vascular bone marrow niches. Cell Rep. 2021 Aug 24;36(8):109618 |
1 | J:182340 Michikami I, Fukushi T, Tanaka M, Egusa H, Maeda Y, Ooshima T, Wakisaka S, Abe M, Kruppel-like factor 4 regulates membranous and endochondral ossification. Exp Cell Res. 2012 Feb 15;318(4):311-25 |
1 | J:67327 Ng YS, Rohan R, Sunday ME, Demello DE, D'Amore PA, Differential expression of VEGF isoforms in mouse during development and in the adult. Dev Dyn. 2001 Feb;220(2):112-21 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1 | J:258274 Patra D, DeLassus E, Mueller J, Abou-Ezzi G, Sandell LJ, Site-1 protease regulates skeletal stem cell population and osteogenic differentiation in mice. Biol Open. 2018 Feb 22;7(2):bio032094 |
1 | J:299239 Qin X, Jiang Q, Nagano K, Moriishi T, Miyazaki T, Komori H, Ito K, Mark KV, Sakane C, Kaneko H, Komori T, Runx2 is essential for the transdifferentiation of chondrocytes into osteoblasts. PLoS Genet. 2020 Nov;16(11):e1009169 |
1 | J:321171 Safwan-Zaiter H, Wagner N, Michiels JF, Wagner KD, Dynamic Spatiotemporal Expression Pattern of the Senescence-Associated Factor p16Ink4a in Development and Aging. Cells. 2022 Feb 4;11(3) |
1 | J:269446 Salguero-Jimenez A, Grego-Bessa J, D'Amato G, Jimenez-Borreguero LJ, de la Pompa JL, Myocardial Notch1-Rbpj deletion does not affect NOTCH signaling, heart development or function. PLoS One. 2018;13(12):e0203100 |
1 | J:187697 Sasaki M, Knobbe CB, Itsumi M, Elia AJ, Harris IS, Chio II, Cairns RA, McCracken S, Wakeham A, Haight J, Ten AY, Snow B, Ueda T, Inoue S, Yamamoto K, Ko M, Rao A, Yen KE, Su SM, Mak TW, D-2-hydroxyglutarate produced by mutant IDH1 perturbs collagen maturation and basement membrane function. Genes Dev. 2012 Sep 15;26(18):2038-49 |
1 | J:187998 Shung CY, Ota S, Zhou ZQ, Keene DR, Hurlin PJ, Disruption of a Sox9-beta-catenin circuit by mutant Fgfr3 in thanatophoric dysplasia type II. Hum Mol Genet. 2012 Nov 1;21(21):4628-44 |
1 | J:191584 Sueyoshi T, Yamamoto K, Akiyama H, Conditional deletion of Tgfbr2 in hypertrophic chondrocytes delays terminal chondrocyte differentiation. Matrix Biol. 2012 Jul;31(6):352-9 |
1 | J:299728 Travisano SI, Oliveira VL, Prados B, Grego-Bessa J, Pineiro-Sabaris R, Bou V, Gomez MJ, Sanchez-Cabo F, MacGrogan D, de la Pompa JL, Coronary arterial development is regulated by a Dll4-Jag1-EphrinB2 signaling cascade. Elife. 2019 Dec 4;8:e49977 |
1 | J:161912 van den Akker NM, Caolo V, Wisse LJ, Peters PP, Poelmann RE, Carmeliet P, Molin DG, Gittenberger-de Groot AC, Developmental coronary maturation is disturbed by aberrant cardiac vascular endothelial growth factor expression and Notch signalling. Cardiovasc Res. 2008 May 1;78(2):366-75 |
1 | J:133799 van den Akker NM, Molin DG, Peters PP, Maas S, Wisse LJ, van Brempt R, van Munsteren CJ, Bartelings MM, Poelmann RE, Carmeliet P, Gittenberger-de Groot AC, Tetralogy of fallot and alterations in vascular endothelial growth factor-A signaling and notch signaling in mouse embryos solely expressing the VEGF120 isoform. Circ Res. 2007 Mar 30;100(6):842-9 |
1 | J:235682 Villacorte M, Delmarcelle AS, Lernoux M, Bouquet M, Lemoine P, Bolsee J, Umans L, de Sousa Lopes SC, Van Der Smissen P, Sasaki T, Bommer G, Henriet P, Refetoff S, Lemaigre FP, Zwijsen A, Courtoy PJ, Pierreux CE, Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly. Development. 2016 Jun 1;143(11):1958-70 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:148141 Wu Q, Chen D, Zuscik MJ, O'Keefe RJ, Rosier RN, Overexpression of Smurf2 stimulates endochondral ossification through upregulation of beta-catenin. J Bone Miner Res. 2008 Apr;23(4):552-63 |
1 | J:115162 Yoshioka M, Yuasa S, Matsumura K, Kimura K, Shiomi T, Kimura N, Shukunami C, Okada Y, Mukai M, Shin H, Yozu R, Sata M, Ogawa S, Hiraki Y, Fukuda K, Chondromodulin-I maintains cardiac valvular function by preventing angiogenesis. Nat Med. 2006 Oct;12(10):1151-9 |
1* | J:99650 Zhao L, Wang K, Ferrara N, Vu TH, Vascular endothelial growth factor co-ordinates proper development of lung epithelium and vasculature. Mech Dev. 2005 Jul-Aug;122(7-8):877-86 |
Vegfb vascular endothelial growth factor B (Synonyms: VEGF-B, Vrf) | |
Results | Reference |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:74493 Maes C, Carmeliet P, Moermans K, Stockmans I, Smets N, Collen D, Bouillon R, Carmeliet G, Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF(164) and VEGF(188). Mech Dev. 2002 Feb;111(1-2):61-73 |
Vegfc vascular endothelial growth factor C (Synonyms: VEGF-C) | |
Results | Reference |
1 | J:302542 Cahill TJ, Sun X, Ravaud C, Villa Del Campo C, Klaourakis K, Lupu IE, Lord AM, Browne C, Jacobsen SEW, Greaves DR, Jackson DG, Cowley SA, James W, Choudhury RP, Vieira JM, Riley PR, Tissue-resident macrophages regulate lymphatic vessel growth and patterning in the developing heart. Development. 2021 Feb 3;148(3):dev194563 |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
1* | J:138863 Hayhurst GP, Strick-Marchand H, Mulet C, Richard AF, Morosan S, Kremsdorf D, Weiss MC, Morphogenetic competence of HNF4alpha-deficient mouse hepatic cells. J Hepatol. 2008 Sep;49(3):384-95 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1* | J:293098 Jafree DJ, Moulding D, Kolatsi-Joannou M, Perretta Tejedor N, Price KL, Milmoe NJ, Walsh CL, Correra RM, Winyard PJ, Harris PC, Ruhrberg C, Walker-Samuel S, Riley PR, Woolf AS, Scambler PJ, Long DA, Spatiotemporal dynamics and heterogeneity of renal lymphatics in mammalian development and cystic kidney disease. Elife. 2019 Dec 6;8:e48183 |
1 | J:199291 Jiang M, Ku WY, Fu J, Offermanns S, Hsu W, Que J, Gpr177 regulates pulmonary vasculature development. Development. 2013 Sep;140(17):3589-94 |
1 | J:107096 Le Bras B, Barallobre MJ, Homman-Ludiye J, Ny A, Wyns S, Tammela T, Haiko P, Karkkainen MJ, Yuan L, Muriel MP, Chatzopoulou E, Breant C, Zalc B, Carmeliet P, Alitalo K, Eichmann A, Thomas JL, VEGF-C is a trophic factor for neural progenitors in the vertebrate embryonic brain. Nat Neurosci. 2006 Mar;9(3):340-8 |
1* | J:74493 Maes C, Carmeliet P, Moermans K, Stockmans I, Smets N, Collen D, Bouillon R, Carmeliet G, Impaired angiogenesis and endochondral bone formation in mice lacking the vascular endothelial growth factor isoforms VEGF(164) and VEGF(188). Mech Dev. 2002 Feb;111(1-2):61-73 |
Vegfd vascular endothelial growth factor D (Synonyms: Figf, VEGF-D) | |
Results | Reference |
1 | J:167063 Gordon EJ, Rao S, Pollard JW, Nutt SL, Lang RA, Harvey NL, Macrophages define dermal lymphatic vessel calibre during development by regulating lymphatic endothelial cell proliferation. Development. 2010 Nov;137(22):3899-910 |
3 | J:76918 Greenberg JM, Thompson FY, Brooks SK, Shannon JM, McCormick-Shannon K, Cameron JE, Mallory BP, Akeson AL, Mesenchymal expression of vascular endothelial growth factors D and A defines vascular patterning in developing lung. Dev Dyn. 2002 Jun;224(2):144-53 |
1 | J:242224 Haller M, Mo Q, Imamoto A, Lamb DJ, Murine model indicates 22q11.2 signaling adaptor CRKL is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2017 May 09;114(19):4981-4986 |
1 | J:186161 Hu B, Castillo E, Harewood L, Ostano P, Reymond A, Dummer R, Raffoul W, Hoetzenecker W, Hofbauer GF, Dotto GP, Multifocal epithelial tumors and field cancerization from loss of mesenchymal CSL signaling. Cell. 2012 Jun 8;149(6):1207-20 |
1 | J:199291 Jiang M, Ku WY, Fu J, Offermanns S, Hsu W, Que J, Gpr177 regulates pulmonary vasculature development. Development. 2013 Sep;140(17):3589-94 |
Vezf1 vascular endothelial zinc finger 1 (Synonyms: db1) | |
Results | Reference |
1* | J:53033 Xiong JW, Leahy A, Lee HH, Stuhlmann H, Vezf1: A Zn finger transcription factor restricted to endothelial cells and their precursors. Dev Biol. 1999 Feb 15;206(2):123-41 |
Vgf VGF nerve growth factor inducible (Synonyms: LOC381677, NERP-4) | |
Results | Reference |
2 | J:331478 Monko T, Rebertus J, Stolley J, Salton SR, Nakagawa Y, Thalamocortical axons regulate neurogenesis and laminar fates in the early sensory cortex. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2201355119 |
Vgll1 vestigial like family member 1 (Synonyms: Tondu) | |
Results | Reference |
1* | J:306471 Niki Y, Kobayashi Y, Moriyama K, Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth. Gene Expr Patterns. 2021 Jun;40:119182 |
Vgll2 vestigial like family member 2 (Synonyms: C130057C21Rik, Vgl-2, Vito1, VITO-1) | |
Results | Reference |
1* | J:306471 Niki Y, Kobayashi Y, Moriyama K, Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth. Gene Expr Patterns. 2021 Jun;40:119182 |
Vgll3 vestigial like family member 3 (Synonyms: 1700110N18Rik, Vito-2) | |
Results | Reference |
1* | J:306471 Niki Y, Kobayashi Y, Moriyama K, Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth. Gene Expr Patterns. 2021 Jun;40:119182 |
Vgll4 vestigial like family member 4 (Synonyms: MGC:54805, VGL-4) | |
Results | Reference |
1* | J:306471 Niki Y, Kobayashi Y, Moriyama K, Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth. Gene Expr Patterns. 2021 Jun;40:119182 |
1 | J:313606 Suo J, Feng X, Li J, Wang J, Wang Z, Zhang L, Zou W, VGLL4 promotes osteoblast differentiation by antagonizing TEADs-inhibited Runx2 transcription. Sci Adv. 2020 Oct;6(43) |
Vhl von Hippel-Lindau tumor suppressor (Synonyms: pVHL, Vhlh) | |
Results | Reference |
1* | J:26614 Kessler PM, Vasavada SP, Rackley RR, Stackhouse T, Duh FM, Latif F, Lerman MI, Zbar B, Williams BR, Expression of the Von Hippel-Lindau tumor suppressor gene, VHL, in human fetal kidney and during mouse embryogenesis. Mol Med. 1995 May;1(4):457-66 |
Vil1 villin 1 (Synonyms: Villin) | |
Results | Reference |
1 | J:194289 Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA, Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium. Dev Biol. 2013 Mar 15;375(2):128-39 |
1* | J:84903 Bolcato-Bellemin AL, Lefebvre O, Arnold C, Sorokin L, Miner JH, Kedinger M, Simon-Assmann P, Laminin alpha5 chain is required for intestinal smooth muscle development. Dev Biol. 2003 Aug 15;260(2):376-90 |
1 | J:76398 Braunstein EM, Qiao XT, Madison B, Pinson K, Dunbar L, Gumucio DL, Villin: A marker for development of the epithelial pyloric border. Dev Dyn. 2002 May;224(1):90-102 |
1* | J:212415 Kinzel B, Pikiolek M, Orsini V, Sprunger J, Isken A, Zietzling S, Desplanches M, Dubost V, Breustedt D, Valdez R, Liu D, Theil D, Muller M, Dietrich B, Bouwmeester T, Ruffner H, Tchorz JS, Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice. Dev Biol. 2014 Jun 15;390(2):181-90 |
1 | J:17719 Landry C, Huet C, Mangeat P, Sahuquet A, Louvard D, Crine P, Comparative analysis of neutral endopeptidase (NEP) and villin gene expression during mouse embryogenesis and enterocyte maturation. Differentiation. 1994 Apr;56(1-2):55-65 |
1 | J:255143 Rasouly HM, Kumar S, Chan S, Pisarek-Horowitz A, Sharma R, Xi QJ, Nishizaki Y, Higashi Y, Salant DJ, Maas RL, Lu W, Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease. Kidney Int. 2016 Dec;90(6):1262-1273 |
1 | J:151981 Spence JR, Lange AW, Lin SC, Kaestner KH, Lowy AM, Kim I, Whitsett JA, Wells JM, Sox17 regulates organ lineage segregation of ventral foregut progenitor cells. Dev Cell. 2009 Jul;17(1):62-74 |
Vim vimentin | |
Results | Reference |
1* | J:325730 Ahuja N, Hiltabidle MS, Rajasekhar H, Voss S, Lu SZ, Barlow HR, Cowdin MA, Daniel E, Vaddaraju V, Anandakumar T, Black E, Cleaver O, Maynard C, Endothelial Cyp26b1 restrains murine heart valve growth during development. Dev Biol. 2022 Jun;486:81-95 |
1 | J:239479 Arora H, Boulberdaa M, Qureshi R, Bitirim V, Messadeq N, Dolle P, Nebigil CG, Prokineticin receptor 1 is required for mesenchymal-epithelial transition in kidney development. FASEB J. 2016 Aug;30(8):2733-40 |
1 | J:199451 Brunne B, Franco S, Bouche E, Herz J, Howell BW, Pahle J, Muller U, May P, Frotscher M, Bock HH, Role of the postnatal radial glial scaffold for the development of the dentate gyrus as revealed by reelin signaling mutant mice. Glia. 2013 Aug;61(8):1347-63 |
1 | J:332132 Cattaneo P, Hayes MGB, Baumgarten N, Hecker D, Peruzzo S, Aslan GS, Kunderfranco P, Larcher V, Zhang L, Contu R, Fonseca G, Spinozzi S, Chen J, Condorelli G, Dimmeler S, Schulz MH, Heinz S, Guimaraes-Camboa N, Evans SM, DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal. Nat Commun. 2022 Dec 2;13(1):7444 |
1 | J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81 |
1* | J:268912 Ducharme P, Zarruk JG, David S, Paquin J, The ferroxidase ceruloplasmin influences Reelin processing, cofilin phosphorylation and neuronal organization in the developing brain. Mol Cell Neurosci. 2018 Oct;92:104-113 |
1 | J:257440 Dvoriantchikova G, Tao W, Pappas S, Gaidosh G, Tse DT, Ivanov D, Pelaez D, Molecular Profiling of the Developing Lacrimal Gland Reveals Putative Role of Notch Signaling in Branching Morphogenesis. Invest Ophthalmol Vis Sci. 2017 Feb 1;58(2):1098-1109 |
1 | J:361578 Feng W, Hong N, Wu Y, Huang J, Zhang Q, Liu G, Qian Z, Chen Y, Jin L, Ding X, Zhao P, Chen AF, Yu Y, Deficiency of Sox7 leads to congenital aortic stenosis via abnormal valve remodeling. J Mol Cell Cardiol. 2025 Feb;199:81-94 |
1 | J:226950 Fogelgren B, Polgar N, Lui VH, Lee AJ, Tamashiro KK, Napoli JA, Walton CB, Zuo X, Lipschutz JH, Urothelial Defects from Targeted Inactivation of Exocyst Sec10 in Mice Cause Ureteropelvic Junction Obstructions. PLoS One. 2015;10(6):e0129346 |
1 | J:306386 Han X, Wei Y, Wu X, Gao J, Yang Z, Zhao C, PDK1 Regulates Transition Period of Apical Progenitors to Basal Progenitors by Controlling Asymmetric Cell Division. Cereb Cortex. 2020 Jan 10;30(1):406-420 |
1 | J:219824 Hendley AM, Provost E, Bailey JM, Wang YJ, Cleveland MH, Blake D, Bittman RW, Roeser JC, Maitra A, Reynolds AB, Leach SD, p120 Catenin is required for normal tubulogenesis but not epithelial integrity in developing mouse pancreas. Dev Biol. 2015 Mar 1;399(1):41-53 |
1 | J:253242 Hu XL, Chen G, Zhang S, Zheng J, Wu J, Bai QR, Wang Y, Li J, Wang H, Feng H, Li J, Sun X, Xia Q, Yang F, Hang J, Qi C, Phoenix TN, Temple S, Shen Q, Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells. Neuron. 2017 Jul 19;95(2):309-325.e6 |
1 | J:146619 Ieda M, Tsuchihashi T, Ivey KN, Ross RS, Hong TT, Shaw RM, Srivastava D, Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling. Dev Cell. 2009 Feb;16(2):233-44 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:173588 Kanazawa T, Ichii O, Otsuka S, Namiki Y, Hashimoto Y, Kon Y, Hepatocyte nuclear factor 4 alpha is associated with mesenchymal-epithelial transition in developing kidneys of C57BL/6 mice. J Vet Med Sci. 2011 May;73(5):601-7 |
1 | J:183083 Katz TC, Singh MK, Degenhardt K, Rivera-Feliciano J, Johnson RL, Epstein JA, Tabin CJ, Distinct compartments of the proepicardial organ give rise to coronary vascular endothelial cells. Dev Cell. 2012 Mar 13;22(3):639-50 |
1 | J:338359 Kaur N, Han W, Li Z, Madrigal MP, Shim S, Pochareddy S, Gulden FO, Li M, Xu X, Xing X, Takeo Y, Li Z, Lu K, Imamura Kawasawa Y, Ballester-Lurbe B, Moreno-Bravo JA, Chedotal A, Terrado J, Perez-Roger I, Koleske AJ, Sestan N, Neural Stem Cells Direct Axon Guidance via Their Radial Fiber Scaffold. Neuron. 2020 Sep 23;107(6):1197-1211.e9 |
1 | J:301558 Lee DH, Olson AW, Wang J, Kim WK, Mi J, Zeng H, Le V, Aldahl J, Hiroto A, Wu X, Sun Z, Androgen action in cell fate and communication during prostate development at single-cell resolution. Development. 2021 Jan 11;148(1):dev196048 |
1* | J:131173 Liu Y, El-Naggar S, Darling DS, Higashi Y, Dean DC, Zeb1 links epithelial-mesenchymal transition and cellular senescence. Development. 2008 Feb;135(3):579-88 |
1 | J:335167 Lu P, Wu B, Wang Y, Russell M, Liu Y, Bernard DJ, Zheng D, Zhou B, Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis. Dev Cell. 2023 Mar 29; |
2 | J:207861 Manthey AL, Lachke SA, FitzGerald PG, Mason RW, Scheiblin DA, McDonald JH, Duncan MK, Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development. Mech Dev. 2014 Feb;131:86-110 |
1 | J:166573 Martinez-Estrada OM, Lettice LA, Essafi A, Guadix JA, Slight J, Velecela V, Hall E, Reichmann J, Devenney PS, Hohenstein P, Hosen N, Hill RE, Munoz-Chapuli R, Hastie ND, Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin. Nat Genet. 2010 Jan;42(1):89-93 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
1* | J:44152 Mollard R, Dziadek M, Homeobox genes from clusters A and B demonstrate characteristics of temporal colinearity and differential restrictions in spatial expression domains in the branching mouse lung. Int J Dev Biol. 1997 Oct;41(5):655-66 |
1 | J:330740 Narayanan R, Pham L, Kerimoglu C, Watanabe T, Castro Hernandez R, Sokpor G, Ulmke PA, Kiszka KA, Tonchev AB, Rosenbusch J, Seong RH, Teichmann U, Frahm J, Fischer A, Bonn S, Stoykova A, Staiger JF, Tuoc T, Chromatin Remodeling BAF155 Subunit Regulates the Genesis of Basal Progenitors in Developing Cortex. iScience. 2018 Jun 29;4:109-126 |
1 | J:328944 Olbertova K, Hrckulak D, Kriz V, Jesionek W, Kubovciak J, Esner M, Korinek V, Buchtova M, Role of LGR5-positive mesenchymal cells in craniofacial development. Front Cell Dev Biol. 2022;10:810527 |
1 | J:287008 Pearson CA, Moore DM, Tucker HO, Dekker JD, Hu H, Miquelajauregui A, Novitch BG, Foxp1 Regulates Neural Stem Cell Self-Renewal and Bias Toward Deep Layer Cortical Fates. Cell Rep. 2020 Feb 11;30(6):1964-1981.e3 |
1 | J:124218 Rasin MR, Gazula VR, Breunig JJ, Kwan KY, Johnson MB, Liu-Chen S, Li HS, Jan LY, Jan YN, Rakic P, Sestan N, Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat Neurosci. 2007 Jul;10(7):819-27 |
1 | J:338071 Sharon N, Chawla R, Mueller J, Vanderhooft J, Whitehorn LJ, Rosenthal B, Gurtler M, Estanboulieh RR, Shvartsman D, Gifford DK, Trapnell C, Melton D, A Peninsular Structure Coordinates Asynchronous Differentiation with Morphogenesis to Generate Pancreatic Islets. Cell. 2019 Feb 7;176(4):790-804.e13 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:279607 Tonchev AB, Tuoc TC, Rosenthal EH, Studer M, Stoykova A, Zbtb20 modulates the sequential generation of neuronal layers in developing cortex. Mol Brain. 2016 Jun 9;9(1):65 |
1 | J:359522 Villeneuve C, Hashmi A, Ylivinkka I, Lawson-Keister E, Miroshnikova YA, Perez-Gonzalez C, Myllymaki SM, Bertillot F, Yadav B, Zhang T, Matic Vignjevic D, Mikkola ML, Manning ML, Wickstrom SA, Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture. Nat Cell Biol. 2024 Feb;26(2):207-218 |
1 | J:362739 Wu Y, Qin K, Xu Y, Rajhans S, Vo T, Lopez KM, Liu J, Nipper MH, Deng J, Yin X, Ramjit LR, Ye Z, Luan Y, Arda HE, Wang P, Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation. Elife. 2024 Jul 25;13 |
1 | J:108702 Zhang CL, Zou Y, Yu RT, Gage FH, Evans RM, Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes Dev. 2006 May 15;20(10):1308-20 |
Vip vasoactive intestinal polypeptide (Synonyms: PHI, peptide histidine isoleucine) | |
Results | Reference |
1* | J:96845 Arnhold S, When M, Labbe D, Andressen C, Addicks K, Transient expression of NOS-II during development of the murine enteric nervous system. J Mol Histol. 2004 Nov;35(8-9):741-8 |
1 | J:257044 Carmona-Alcocer V, Abel JH, Sun TC, Petzold LR, Doyle FJ 3rd, Simms CL, Herzog ED, Ontogeny of Circadian Rhythms and Synchrony in the Suprachiasmatic Nucleus. J Neurosci. 2018 Feb 7;38(6):1326-1334 |
1 | J:166770 Coppola E, d'Autreaux F, Rijli FM, Brunet JF, Ongoing roles of Phox2 homeodomain transcription factors during neuronal differentiation. Development. 2010 Dec;137(24):4211-20 |
1 | J:199638 Huang T, Hu J, Wang B, Nie Y, Geng J, Cheng L, Tlx3 controls cholinergic transmitter and Peptide phenotypes in a subset of prenatal sympathetic neurons. J Neurosci. 2013 Jun 26;33(26):10667-75 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
1* | J:42766 Sang Q, Young HM, Development of nicotinic receptor clusters and innervation accompanying the change in muscle phenotype in the mouse esophagus. J Comp Neurol. 1997 Sep 15;386(1):119-36 |
1 | J:52906 Spong CY, Lee SJ, McCune SK, Gibney G, Abebe DT, Alvero R, Brenneman DE, Hill JM, Maternal regulation of embryonic growth: the role of vasoactive intestinal peptide. Endocrinology. 1999 Feb;140(2):917-24 |
2* | J:31877 Waschek JA, Ellison J, Bravo DT, Handley V, Embryonic expression of vasoactive intestinal peptide (VIP) and VIP receptor genes. J Neurochem. 1996 Apr;66(4):1762-5 |
Vipr1 vasoactive intestinal peptide receptor 1 (Synonyms: VIP-R1, VIP receptor subtype 1, VPAC1) | |
Results | Reference |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
Vipr2 vasoactive intestinal peptide receptor 2 (Synonyms: Vip2, VIP receptor subtype 2, VPAC2, VPAC2R) | |
Results | Reference |
1 | J:257044 Carmona-Alcocer V, Abel JH, Sun TC, Petzold LR, Doyle FJ 3rd, Simms CL, Herzog ED, Ontogeny of Circadian Rhythms and Synchrony in the Suprachiasmatic Nucleus. J Neurosci. 2018 Feb 7;38(6):1326-1334 |
1 | J:185665 Guo Z, Zhao C, Huang M, Huang T, Fan M, Xie Z, Chen Y, Zhao X, Xia G, Geng J, Cheng L, Tlx1/3 and ptf1a control the expression of distinct sets of transmitter and Peptide receptor genes in the developing dorsal spinal cord. J Neurosci. 2012 Jun 20;32(25):8509-20 |
1* | J:31877 Waschek JA, Ellison J, Bravo DT, Handley V, Embryonic expression of vasoactive intestinal peptide (VIP) and VIP receptor genes. J Neurochem. 1996 Apr;66(4):1762-5 |
Vit vitrin (Synonyms: 1700052E02Rik, 1700110E08Rik, 2810429K11Rik, AKH, akhirin) | |
Results | Reference |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Vkorc1 vitamin K epoxide reductase complex, subunit 1 (Synonyms: D7Wsu86e) | |
Results | Reference |
2* | J:262230 Lacombe J, Rishavy MA, Berkner KL, Ferron M, VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo. JCI Insight. 2018 Jan 11;3(1) |
Vkorc1l1 vitamin K epoxide reductase complex, subunit 1-like 1 (Synonyms: 2310024K08Rik) | |
Results | Reference |
2* | J:262230 Lacombe J, Rishavy MA, Berkner KL, Ferron M, VKOR paralog VKORC1L1 supports vitamin K-dependent protein carboxylation in vivo. JCI Insight. 2018 Jan 11;3(1) |
Vldlr very low density lipoprotein receptor | |
Results | Reference |
1 | J:219839 Hirota Y, Kubo K, Katayama K, Honda T, Fujino T, Yamamoto TT, Nakajima K, Reelin receptors ApoER2 and VLDLR are expressed in distinct spatiotemporal patterns in developing mouse cerebral cortex. J Comp Neurol. 2015 Feb 15;523(3):463-78 |
2 | J:299731 Kohno T, Ishii K, Hirota Y, Honda T, Makino M, Kawasaki T, Nakajima K, Hattori M, Reelin-Nrp1 Interaction Regulates Neocortical Dendrite Development in a Context-Specific Manner. J Neurosci. 2020 Oct 21;40(43):8248-8261 |
1* | J:82121 Luque JM, Morante-Oria J, Fairen A, Localization of ApoER2, VLDLR and Dab1 in radial glia: groundwork for a new model of reelin action during cortical development. Brain Res Dev Brain Res. 2003 Feb 16;140(2):195-203 |
1 | J:171375 Senturk A, Pfennig S, Weiss A, Burk K, Acker-Palmer A, Ephrin Bs are essential components of the Reelin pathway to regulate neuronal migration. Nature. 2011 Apr 21;472(7343):356-60 |
1 | J:77999 Sugitani Y, Nakai S, Minowa O, Nishi M, Jishage K, Kawano H, Mori K, Ogawa M, Noda T, Brn-1 and Brn-2 share crucial roles in the production and positioning of mouse neocortical neurons. Genes Dev. 2002 Jul 15;16(14):1760-5 |
Vma21 VMA21 vacuolar H+-ATPase homolog (S. cerevisiae) (Synonyms: 2610030H06Rik) | |
Results | Reference |
1* | J:343515 Cocchiararo I, Cattaneo O, Rajendran J, Chabry F, Cornut M, Soldati H, Bigot A, Mamchaoui K, Gibertini S, Bouche A, Ham DJ, Laumonier T, Prola A, Castets P, Identification of a muscle-specific isoform of VMA21 as a potent actor in X-linked myopathy with excessive autophagy pathogenesis. Hum Mol Genet. 2023 Dec 1;32(24):3374-3389 |
Vmn1r45 vomeronasal 1 receptor 45 (Synonyms: V1r2, V1ra2) | |
Results | Reference |
1 | J:111616 Karunadasa DK, Chapman C, Bicknell RJ, Expression of pheromone receptor gene families during olfactory development in the mouse: expression of a V1 receptor in the main olfactory epithelium. Eur J Neurosci. 2006 May;23(10):2563-72 |
Vmn1r51 vomeronasal 1 receptor 51 (Synonyms: V1r1, V1ra1, VN12) | |
Results | Reference |
1 | J:111616 Karunadasa DK, Chapman C, Bicknell RJ, Expression of pheromone receptor gene families during olfactory development in the mouse: expression of a V1 receptor in the main olfactory epithelium. Eur J Neurosci. 2006 May;23(10):2563-72 |
Vmn1r180 vomeronasal 1 receptor 180 (Synonyms: LOC232962, V1rd16) | |
Results | Reference |
1 | J:174520 Enomoto T, Ohmoto M, Iwata T, Uno A, Saitou M, Yamaguchi T, Kominami R, Matsumoto I, Hirota J, Bcl11b/Ctip2 Controls the Differentiation of Vomeronasal Sensory Neurons in Mice. J Neurosci. 2011 Jul 13;31(28):10159-10173 |
Vnn1 vanin 1 (Synonyms: pantetheinase, V-1) | |
Results | Reference |
1 | J:64333 Bowles J, Bullejos M, Koopman P, A subtractive gene expression screen suggests a role for vanin-1 in testis development in mice. Genesis. 2000 Jul;27(3):124-35 |
1 | J:80150 Koopman P, Bullejos M, Loffler K, Bowles J, Expression-based strategies for discovery of genes involved in testis and ovary development. Novartis Found Symp. 2002;244:240-9; discussion 249-57 |
1* | J:96928 Wilson MJ, Jeyasuria P, Parker KL, Koopman P, The transcription factors steroidogenic factor-1 and SOX9 regulate expression of Vanin-1 during mouse testis development. J Biol Chem. 2005 Feb 18;280(7):5917-23 |
Vps4a vacuolar protein sorting 4A (Synonyms: 4930589C15Rik, MGC:11698) | |
Results | Reference |
1* | J:339600 Hermosilla Aguayo V, Martin P, Tian N, Zheng J, Aho R, Losa M, Selleri L, ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42 |
Vps13c vacuolar protein sorting 13C (Synonyms: C230055H22Rik) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Vps25 vacuolar protein sorting 25 (Synonyms: 1110020N13Rik, D11Wsu68e) | |
Results | Reference |
1* | J:339600 Hermosilla Aguayo V, Martin P, Tian N, Zheng J, Aho R, Losa M, Selleri L, ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42 |
Vps26a VPS26 retromer complex component A (Synonyms: HB58, H beta 58, Vps26) | |
Results | Reference |
1* | J:1105 Lee JJ, Radice G, Perkins CP, Costantini F, Identification and characterization of a novel, evolutionarily conserved gene disrupted by the murine H beta 58 embryonic lethal transgene insertion. Development. 1992 May;115(1):277-88 |
Vps35 VPS35 retromer complex component (Synonyms: Mem3) | |
Results | Reference |
1 | J:280216 Liu W, Tang FL, Erion J, Xiao H, Ye J, Xiong WC, Vps35 haploinsufficiency results in degenerative-like deficit in mouse retinal ganglion neurons and impairment of optic nerve injury-induced gliosis. Mol Brain. 2014 Feb 11;7:10 |
Vps36 vacuolar protein sorting 36 (Synonyms: 1700010A24Rik, 2210415M20Rik, 2810408E15Rik, Eap45) | |
Results | Reference |
1* | J:339600 Hermosilla Aguayo V, Martin P, Tian N, Zheng J, Aho R, Losa M, Selleri L, ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42 |
Vps37a vacuolar protein sorting 37A (Synonyms: 2210018P21Rik, 4930592A21Rik, D8Ertd531e) | |
Results | Reference |
1* | J:339600 Hermosilla Aguayo V, Martin P, Tian N, Zheng J, Aho R, Losa M, Selleri L, ESCRT-dependent control of craniofacial morphogenesis with concomitant perturbation of NOTCH signaling. Dev Biol. 2023 Aug 10;503:25-42 |
Vps72 vacuolar protein sorting 72 (Synonyms: Tcfl1, YL-1) | |
Results | Reference |
1* | J:305946 Xu M, Yao J, Shi Y, Yi H, Zhao W, Lin X, Yang Z, The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026 |
Vrk1 vaccinia related kinase 1 (Synonyms: 51PK) | |
Results | Reference |
1* | J:83672 Vega FM, Gonzalo P, Gaspar ML, Lazo PA, Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators in murine hematopoietic development. FEBS Lett. 2003 Jun 5;544(1-3):176-80 |
Vrk2 vaccinia related kinase 2 (Synonyms: 2810003O05Rik) | |
Results | Reference |
1* | J:83672 Vega FM, Gonzalo P, Gaspar ML, Lazo PA, Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators in murine hematopoietic development. FEBS Lett. 2003 Jun 5;544(1-3):176-80 |
Vrk3 vaccinia related kinase 3 | |
Results | Reference |
1* | J:83672 Vega FM, Gonzalo P, Gaspar ML, Lazo PA, Expression of the VRK (vaccinia-related kinase) gene family of p53 regulators in murine hematopoietic development. FEBS Lett. 2003 Jun 5;544(1-3):176-80 |
Vsig1 V-set and immunoglobulin domain containing 1 (Synonyms: 1700062D20Rik, 4930405J24Rik) | |
Results | Reference |
1* | J:178119 Oidovsambuu O, Nyamsuren G, Liu S, Goring W, Engel W, Adham IM, Adhesion protein VSIG1 is required for the proper differentiation of glandular gastric epithelia. PLoS One. 2011;6(10):e25908 |
Vsnl1 visinin-like 1 (Synonyms: VILIP) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
Vstm2a V-set and transmembrane domain containing 2A (Synonyms: 9330184N17Rik, MGC:38877, Vstm2) | |
Results | Reference |
1 | J:239160 Secco B, Camire E, Briere MA, Caron A, Billong A, Gelinas Y, Lemay AM, Tharp KM, Lee PL, Gobeil S, Guimond JV, Patey N, Guertin DA, Stahl A, Haddad E, Marsolais D, Bosse Y, Birsoy K, Laplante M, Amplification of Adipogenic Commitment by VSTM2A. Cell Rep. 2017 Jan 03;18(1):93-106 |
Vsx1 visual system homeobox 1 (Synonyms: CHX10-like) | |
Results | Reference |
1 | J:219894 Mattar P, Ericson J, Blackshaw S, Cayouette M, A conserved regulatory logic controls temporal identity in mouse neural progenitors. Neuron. 2015 Feb 4;85(3):497-504 |
Vsx2 visual system homeobox 2 (Synonyms: Chx10, Hox-10, Hox10) | |
Results | Reference |
1 | J:188155 Bharti K, Gasper M, Ou J, Brucato M, Clore-Gronenborn K, Pickel J, Arnheiter H, A regulatory loop involving PAX6, MITF, and WNT signaling controls retinal pigment epithelium development. PLoS Genet. 2012 Jul;8(7):e1002757 |
1 | J:341148 Bosze B, Suarez-Navarro J, Cajias I, Brzezinski Iv JA, Brown NL, Notch pathway mutants do not equivalently perturb mouse embryonic retinal development. PLoS Genet. 2023 Sep;19(9):e1010928 |
2 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1* | J:332642 Cohen-Gulkar M, David A, Messika-Gold N, Eshel M, Ovadia S, Zuk-Bar N, Idelson M, Cohen-Tayar Y, Reubinoff B, Ziv T, Shamay M, Elkon R, Ashery-Padan R, The LHX2-OTX2 transcriptional regulatory module controls retinal pigmented epithelium differentiation and underlies genetic risk for age-related macular degeneration. PLoS Biol. 2023 Jan;21(1):e3001924 |
1 | J:304642 Dupacova N, Antosova B, Paces J, Kozmik Z, Meis homeobox genes control progenitor competence in the retina. Proc Natl Acad Sci U S A. 2021 Mar 23;118(12):e2013136118 |
1 | J:176438 Esteve P, Sandonis A, Ibanez C, Shimono A, Guerrero I, Bovolenta P, Secreted frizzled-related proteins are required for Wnt/{beta}-catenin signalling activation in the vertebrate optic cup. Development. 2011 Oct;138(19):4179-84 |
1 | J:249145 Goetz JJ, Laboissonniere LA, Wester AK, Lynch MR, Trimarchi JM, Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression. PLoS One. 2016;11(3):e0150878 |
1 | J:223559 Goetz JJ, Martin GM, Chowdhury R, Trimarchi JM, Onecut1 and Onecut2 play critical roles in the development of the mouse retina. PLoS One. 2014;9(10):e110194 |
1* | J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347 |
1 | J:239986 Lahti L, Haugas M, Tikker L, Airavaara M, Voutilainen MH, Anttila J, Kumar S, Inkinen C, Salminen M, Partanen J, Differentiation and molecular heterogeneity of inhibitory and excitatory neurons associated with midbrain dopaminergic nuclei. Development. 2016 Feb 01;143(3):516-29 |
1* | J:19939 Liu IS, Chen JD, Ploder L, Vidgen D, van der Kooy D, Kalnins VI, McInnes RR, Developmental expression of a novel murine homeobox gene (Chx10): evidence for roles in determination of the neuroretina and inner nuclear layer. Neuron. 1994 Aug;13(2):377-93 |
1 | J:170543 Matsushima D, Heavner W, Pevny LH, Combinatorial regulation of optic cup progenitor cell fate by SOX2 and PAX6. Development. 2011 Feb;138(3):443-54 |
1 | J:187391 Pacal M, Bremner R, Mapping differentiation kinetics in the mouse retina reveals an extensive period of cell cycle protein expression in post-mitotic newborn neurons. Dev Dyn. 2012 Oct;241(10):1525-44 |
1* | J:98542 Rowan S, Cepko CL, A POU factor binding site upstream of the Chx10 homeobox gene is required for Chx10 expression in subsets of retinal progenitor cells and bipolar cells. Dev Biol. 2005 May 15;281(2):240-55 |
1 | J:287023 Schnerwitzki D, Perry S, Ivanova A, Caixeta FV, Cramer P, Gunther S, Weber K, Tafreshiha A, Becker L, Vargas Panesso IL, Klopstock T, Hrabe de Angelis M, Schmidt M, Kullander K, Englert C, Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord. Life Sci Alliance. 2018 Aug;1(4):e201800106 |
1 | J:84301 Stolt CC, Lommes P, Sock E, Chaboissier MC, Schedl A, Wegner M, The Sox9 transcription factor determines glial fate choice in the developing spinal cord. Genes Dev. 2003 Jul 1;17(13):1677-89 |
1 | J:280461 Xiao D, Jin K, Xiang M, Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development. Front Mol Neurosci. 2018;11:271 |
1 | J:108702 Zhang CL, Zou Y, Yu RT, Gage FH, Evans RM, Nuclear receptor TLX prevents retinal dystrophy and recruits the corepressor atrophin1. Genes Dev. 2006 May 15;20(10):1308-20 |
Vti1a vesicle transport through interaction with t-SNAREs 1A (Synonyms: 1110014F16Rik, 1110018K19Rik, 4921537J05Rik, Vti1-rp2) | |
Results | Reference |
1* | J:169107 Kunwar AJ, Rickmann M, Backofen B, Browski SM, Rosenbusch J, Schoning S, Fleischmann T, Krieglstein K, Fischer von Mollard G, Lack of the endosomal SNAREs vti1a and vti1b led to significant impairments in neuronal development. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2575-80 |
1 | J:308136 Sokpor G, Rosenbusch J, Kunwar AJ, Rickmann M, Tuoc T, Rizzoli SO, Tarabykin V, von Mollard GF, Krieglstein K, Staiger JF, Ablation of Vti1a/1b Triggers Neural Progenitor Pool Depletion and Cortical Layer 5 Malformation in Late-embryonic Mouse Cortex. Neuroscience. 2021 May 21;463:303-316 |
Vti1b vesicle transport through interaction with t-SNAREs 1B (Synonyms: Vti1-rp1) | |
Results | Reference |
1* | J:169107 Kunwar AJ, Rickmann M, Backofen B, Browski SM, Rosenbusch J, Schoning S, Fleischmann T, Krieglstein K, Fischer von Mollard G, Lack of the endosomal SNAREs vti1a and vti1b led to significant impairments in neuronal development. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2575-80 |
1 | J:308136 Sokpor G, Rosenbusch J, Kunwar AJ, Rickmann M, Tuoc T, Rizzoli SO, Tarabykin V, von Mollard GF, Krieglstein K, Staiger JF, Ablation of Vti1a/1b Triggers Neural Progenitor Pool Depletion and Cortical Layer 5 Malformation in Late-embryonic Mouse Cortex. Neuroscience. 2021 May 21;463:303-316 |
Vtn vitronectin (Synonyms: Vn) | |
Results | Reference |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
2* | J:25543 Seiffert D, Iruela-Arispe ML, Sage EH, Loskutoff DJ, Distribution of vitronectin mRNA during murine development. Dev Dyn. 1995 May;203(1):71-9 |
Vwa1 von Willebrand factor A domain containing 1 (Synonyms: 4932416A11Rik, WARP) | |
Results | Reference |
1 | J:139369 Allen JM, Brachvogel B, Farlie PG, Fitzgerald J, Bateman JF, The extracellular matrix protein WARP is a novel component of a distinct subset of basement membranes. Matrix Biol. 2008 May;27(4):295-305 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
Vwc2 von Willebrand factor C domain containing 2 (Synonyms: A930041G11Rik, Brorin, cradin) | |
Results | Reference |
2* | J:122704 Koike N, Kassai Y, Kouta Y, Miwa H, Konishi M, Itoh N, Brorin, a novel secreted bone morphogenetic protein antagonist, promotes neurogenesis in mouse neural precursor cells. J Biol Chem. 2007 May 25;282(21):15843-50 |
1* | J:139122 Manabe R, Tsutsui K, Yamada T, Kimura M, Nakano I, Shimono C, Sanzen N, Furutani Y, Fukuda T, Oguri Y, Shimamoto K, Kiyozumi D, Sato Y, Sado Y, Senoo H, Yamashina S, Fukuda S, Kawai J, Sugiura N, Kimata K, Hayashizaki Y, Sekiguchi K, Transcriptome-based systematic identification of extracellular matrix proteins. Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):12849-54 |
1* | J:154664 Miwa H, Miyake A, Kouta Y, Shimada A, Yamashita Y, Nakayama Y, Yamauchi H, Konishi M, Itoh N, A novel neural-specific BMP antagonist, Brorin-like, of the Chordin family. FEBS Lett. 2009 Nov 19;583(22):3643-8 |
Vwc2l von Willebrand factor C domain-containing protein 2-like (Synonyms: A830006F12Rik, Brl, brorin-like) | |
Results | Reference |
1* | J:154664 Miwa H, Miyake A, Kouta Y, Shimada A, Yamashita Y, Nakayama Y, Yamauchi H, Konishi M, Itoh N, A novel neural-specific BMP antagonist, Brorin-like, of the Chordin family. FEBS Lett. 2009 Nov 19;583(22):3643-8 |
Vwf Von Willebrand factor (Synonyms: 6820430P06Rik, B130011O06Rik) | |
Results | Reference |
1* | J:305967 Abid MR, Yi X, Yano K, Shih SC, Aird WC, Vascular endocan is preferentially expressed in tumor endothelium. Microvasc Res. 2006 Nov;72(3):136-45 |
1 | J:232617 Chen Z, Yue SX, Zhou G, Greenfield EM, Murakami S, ERK1 and ERK2 regulate chondrocyte terminal differentiation during endochondral bone formation. J Bone Miner Res. 2015 May;30(5):765-74 |
1 | J:231667 Munger SJ, Geng X, Srinivasan RS, Witte MH, Paul DL, Simon AM, Segregated Foxc2, NFATc1 and Connexin expression at normal developing venous valves, and Connexin-specific differences in the valve phenotypes of Cx37, Cx43, and Cx47 knockout mice. Dev Biol. 2016 Apr 15;412(2):173-90 |
1 | J:159267 Plante J, Simard M, Rantakari P, Cote M, Provost PR, Poutanen M, Tremblay Y, Epithelial cells are the major site of hydroxysteroid (17beta) dehydrogenase 2 and androgen receptor expression in fetal mouse lungs during the period overlapping the surge of surfactant. J Steroid Biochem Mol Biol. 2009 Nov;117(4-5):139-45 |
1* | J:18811 Sheppard AM, Onken MD, Rosen GD, Noakes PG, Dean DC, Expanding roles for alpha 4 integrin and its ligands in development. Cell Adhes Commun. 1994 Apr;2(1):27-43 |
1 | J:251917 Wang Y, Wu B, Lu P, Zhang D, Wu B, Varshney S, Del Monte-Nieto G, Zhuang Z, Charafeddine R, Kramer AH, Sibinga NE, Frangogiannis NG, Kitsis RN, Adams RH, Alitalo K, Sharp DJ, Harvey RP, Stanley P, Zhou B, Uncontrolled angiogenic precursor expansion causes coronary artery anomalies in mice lacking Pofut1. Nat Commun. 2017 Sep 18;8(1):578 |
1 | J:143763 Zhang Y, Singh MK, Degenhardt KR, Lu MM, Bennett J, Yoshida Y, Epstein JA, Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects. Dev Biol. 2009 Jan 1;325(1):82-93 |
Wac WW domain containing adaptor with coiled-coil (Synonyms: 1110067P07Rik, A230035H12Rik, Wwp4) | |
Results | Reference |
1* | J:344859 Nishikawa M, Matsuki T, Hamada N, Nakayama A, Ito H, Nagata KI, Expression analyses of WAC, a responsible gene for neurodevelopmental disorders, during mouse brain development. Med Mol Morphol. 2023 Dec;56(4):266-273 |
Wap whey acidic protein | |
Results | Reference |
1 | J:356957 Rogers RL, Van Seuningen I, Gould J, Hertzog PJ, Naylor MJ, Pritchard MA, Transcript profiling of Elf5+/- mammary glands during pregnancy identifies novel targets of Elf5. PLoS One. 2010 Oct 7;5(10):e13150 |
Wars1 tryptophanyl-tRNA synthetase1 (Synonyms: Wars) | |
Results | Reference |
1 | J:108133 Sekita Y, Wagatsuma H, Irie M, Kobayashi S, Kohda T, Matsuda J, Yokoyama M, Ogura A, Schuster-Gossler K, Gossler A, Ishino F, Kaneko-Ishino T, Aberrant regulation of imprinted gene expression in Gtl2lacZ mice. Cytogenet Genome Res. 2006;113(1-4):223-9 |
Wasf1 WASP family, member 1 (Synonyms: Scar, WAVE, WAVE-1) | |
Results | Reference |
1 | J:180006 Yokoyama K, Tezuka T, Kotani M, Nakazawa T, Hoshina N, Shimoda Y, Kakuta S, Sudo K, Watanabe K, Iwakura Y, Yamamoto T, NYAP: a phosphoprotein family that links PI3K to WAVE1 signalling in neurons. EMBO J. 2011 Nov 30;30(23):4739-54 |
Wasl WASP like actin nucleation promoting factor (Synonyms: 2900021I12Rik, 3110031I02Rik, N-WASP, Wiskott-Aldrich syndrome-like (human)) | |
Results | Reference |
1* | J:224930 Cheerathodi M, Vincent JJ, Ballif BA, Quantitative comparison of CrkL-SH3 binding proteins from embryonic murine brain and liver: Implications for developmental signaling and the quantification of protein species variants in bottom-up proteomics. J Proteomics. 2015 Jul 1;125:104-11 |
Wdfy1 WD repeat and FYVE domain containing 1 (Synonyms: 1700013B03Rik, 1700120F24Rik, Jr1) | |
Results | Reference |
1* | J:129949 Cui CY, Kunisada M, Esibizione D, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet. 2007 Nov 1;16(21):2583-90 |
Wdfy3 WD repeat and FYVE domain containing 3 (Synonyms: 2610509D04Rik, Alfy, Bchs, Bwf1, D5Ertd66e, Ggtb3, mKIAA0993) | |
Results | Reference |
1* | J:285853 Zhang S, Song Z, An L, Liu X, Hu XW, Naz A, Zhou R, Guo X, He L, Zhu H, WD40 repeat and FYVE domain containing 3 is essential for cardiac development. Cardiovasc Res. 2019 Jul 1;115(8):1320-1331 |
Wdr1 WD repeat domain 1 (Synonyms: Aip1, D5Wsu185e, rede) | |
Results | Reference |
1 | J:211364 Yuan B, Wan P, Chu D, Nie J, Cao Y, Luo W, Lu S, Chen J, Yang Z, A Cardiomyocyte-Specific Wdr1 Knockout Demonstrates Essential Functional Roles for Actin Disassembly during Myocardial Growth and Maintenance in Mice. Am J Pathol. 2014 Jul;184(7):1967-80 |
Wdr4 WD repeat domain 4 (Synonyms: D530049K22Rik, Wh) | |
Results | Reference |
1* | J:355649 Li Q, Jiang S, Lei K, Han H, Chen Y, Lin W, Xiong Q, Qi X, Gan X, Sheng R, Wang Y, Zhang Y, Ma J, Li T, Lin S, Zhou C, Chen D, Yuan Q, Metabolic rewiring during bone development underlies tRNA m7G-associated primordial dwarfism. J Clin Invest. 2024 Sep 10;134(20) |
Wdr35 WD repeat domain 35 (Synonyms: 4930459M12Rik) | |
Results | Reference |
1* | J:193641 Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Banfi B, A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx waltzer mouse. PLoS Genet. 2012;8(10):e1002966 |
Wdr47 WD repeat domain 47 (Synonyms: 1810073M12Rik, mKIAA0893, nemitin) | |
Results | Reference |
2 | J:249035 Kannan M, Bayam E, Wagner C, Rinaldi B, Kretz PF, Tilly P, Roos M, McGillewie L, Bar S, Minocha S, Chevalier C, Po C, Chelly J, Mandel JL, Borgatti R, Piton A, Kinnear C, Loos B, Adams DJ, Herault Y, Collins SC, Friant S, Godin JD, Yalcin B, WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):E9308-E9317 |
Wdr62 WD repeat domain 62 (Synonyms: 2310038K02Rik, MGC:31423) | |
Results | Reference |
1* | J:163909 Bilguvar K, Ozturk AK, Louvi A, Kwan KY, Choi M, Tatli B, Yalnizoglu D, Tuysuz B, Caglayan AO, Gokben S, Kaymakcalan H, Barak T, Bakircioglu M, Yasuno K, Ho W, Sanders S, Zhu Y, Yilmaz S, Dincer A, Johnson MH, Bronen RA, Kocer N, Per H, Mane S, Pamir MN,Yalcinkaya C, Kumandas S, Topcu M, Ozmen M, Sestan N, Lifton RP, State MW, Gunel M, Whole-exome sequencing identifies recessive WDR62 mutations in severe brain malformations. Nature. 2010 Sep 9;467(7312):207-10 |
1 | J:224504 Chen JF, Zhang Y, Wilde J, Hansen KC, Lai F, Niswander L, Microcephaly disease gene Wdr62 regulates mitotic progression of embryonic neural stem cells and brain size. Nat Commun. 2014;5:3885 |
1 | J:266305 Zhou Y, Qin Y, Qin Y, Xu B, Guo T, Ke H, Chen M, Zhang L, Han F, Li Y, Chen M, Behrens A, Wang Y, Xu Z, Chen ZJ, Gao F, Wdr62 is involved in female meiotic initiation via activating JNK signaling and associated with POI in humans. PLoS Genet. 2018 Aug;14(8):e1007463 |
Wdr77 WD repeat domain 77 (Synonyms: 2610003I18Rik, 2610312E17Rik, p44/MEP50) | |
Results | Reference |
1 | J:356915 Ichiyanagi T, Ichiyanagi K, Ogawa A, Kuramochi-Miyagawa S, Nakano T, Chuma S, Sasaki H, Udono H, HSP90alpha plays an important role in piRNA biogenesis and retrotransposon repression in mouse. Nucleic Acids Res. 2014 Oct 29;42(19):11903-11 |
Wdr81 WD repeat domain 81 (Synonyms: MGC:32441, MGC32441, nur5, shakey 5) | |
Results | Reference |
1* | J:318768 Carpentieri JA, Di Cicco A, Lampic M, Andreau D, Del Maestro L, El Marjou F, Coquand L, Bahi-Buisson N, Brault JB, Baffet AD, Endosomal trafficking defects alter neural progenitor proliferation and cause microcephaly. Nat Commun. 2022 Jan 10;13(1):16 |
Wfdc1 WAP four-disulfide core domain 1 (Synonyms: 2310058A03Rik, ps20) | |
Results | Reference |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Wfdc2 WAP four-disulfide core domain 2 (Synonyms: 1600023A02Rik, HE4, WAP5) | |
Results | Reference |
2 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1 | J:322227 Ljungberg MC, Sadi M, Wang Y, Aronow BJ, Xu Y, Kao RJ, Liu Y, Gaddis N, Ardini-Poleske ME, Umrod T, Ambalavanan N, Nicola T, Kaminski N, Ahangari F, Sontag R, Corley RA, Ansong C, Carson JP, Spatial distribution of marker gene activity in the mouse lung during alveolarization. Data Brief. 2019 Feb;22:365-372 |
Wfdc18 WAP four-disulfide core domain 18 (Synonyms: Expi, Kal1, WDNM1) | |
Results | Reference |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
Wfs1 wolframin ER transmembrane glycoprotein (Synonyms: wolframin, Wolfram syndrome 1 homolog (human)) | |
Results | Reference |
1* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1* | J:210446 Tekko T, Lillevali K, Luuk H, Sutt S, Truu L, Ord T, Mols M, Vasar E, Initiation and developmental dynamics of Wfs1 expression in the context of neural differentiation and ER stress in mouse forebrain. Int J Dev Neurosci. 2014 Jun;35:80-8 |
Whrn whirlin (Synonyms: 1110035G07Rik, C430046P22Rik, Dfnb31, mKIAA1526, Ush2d, wi) | |
Results | Reference |
1 | J:86904 Mburu P, Mustapha M, Varela A, Weil D, El-Amraoui A, Holme RH, Rump A, Hardisty RE, Blanchard S, Coimbra RS, Perfettini I, Parkinson N, Mallon AM, Glenister P, Rogers MJ, Paige AJ, Moir L, Clay J, Rosenthal A, Liu XZ, Blanco G, Steel KP, Petit C, Brown SD, Defects in whirlin, a PDZ domain molecule involved in stereocilia elongation, cause deafness in the whirler mouse and families with DFNB31. Nat Genet. 2003 Aug;34(4):421-8 |
1 | J:271898 Tadenev ALD, Akturk A, Devanney N, Mathur PD, Clark AM, Yang J, Tarchini B, GPSM2-GNAI Specifies the Tallest Stereocilia and Defines Hair Bundle Row Identity. Curr Biol. 2019 Feb 19; |
1* | J:106765 van Wijk E, van der Zwaag B, Peters T, Zimmermann U, Te Brinke H, Kersten FF, Marker T, Aller E, Hoefsloot LH, Cremers CW, Cremers FP, Wolfrum U, Knipper M, Roepman R, Kremer H, The DFNB31 gene product whirlin connects to the Usher protein network in the cochlea and retina by direct association with USH2A and VLGR1. Hum Mol Genet. 2006 Mar 1;15(5):751-65 |
Wif1 Wnt inhibitory factor 1 (Synonyms: WIF-1) | |
Results | Reference |
1* | J:138291 Hu YA, Gu X, Liu J, Yang Y, Yan Y, Zhao C, Expression pattern of Wnt inhibitor factor 1(Wif1) during the development in mouse CNS. Gene Expr Patterns. 2008 Sep;8(7-8):515-522 |
1* | J:192625 Keil KP, Mehta V, Branam AM, Abler LL, Buresh-Stiemke RA, Joshi PS, Schmitz CT, Marker PC, Vezina CM, Wnt inhibitory factor 1 (Wif1) is regulated by androgens and enhances androgen-dependent prostate development. Endocrinology. 2012 Dec;153(12):6091-103 |
1 | J:188148 Landin MA, Shabestari M, Babaie E, Reseland JE, Osmundsen H, Gene Expression Profiling during Murine Tooth Development. Front Genet. 2012;3:139 |
2* | J:316292 Lee MJ, Kim EJ, Li L, Jung HS, Roles of Wnt inhibitory factor 1 during tooth morphogenesis. Cell Tissue Res. 2015 Oct;362(1):61-8 |
1 | J:213466 Lu D, Dong W, Zhang X, Quan X, Bao D, Lu Y, Zhang L, WIF1 causes dysfunction of heart in transgenic mice. Transgenic Res. 2013 Dec;22(6):1179-89 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:132011 Sun J, Chen H, Chen C, Whitsett JA, Mishina Y, Bringas P Jr, Ma JC, Warburton D, Shi W, Prenatal lung epithelial cell-specific abrogation of alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation. Am J Pathol. 2008 Mar;172(3):571-82 |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Wipi1 WD repeat domain, phosphoinositide interacting 1 (Synonyms: 4930533H01Rik, D11Ertd498e) | |
Results | Reference |
1 | J:233601 Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP, Harwood CA, Byrne C, O'Shaughnessy RF, Bergamaschi D, Constitutive Autophagy and Nucleophagy during Epidermal Differentiation. J Invest Dermatol. 2016 Jul;136(7):1460-70 |
Wls wntless WNT ligand secretion mediator (Synonyms: 5031439A09Rik, Gpr177) | |
Results | Reference |
2 | J:306218 Landin Malt A, Hogan AK, Smith CD, Madani MS, Lu X, Wnts regulate planar cell polarity via heterotrimeric G protein and PI3K signaling. J Cell Biol. 2020 Oct 5;219(10) |
3 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
1* | J:311540 Oliver BL, Young CA, Munnamalai V, Spatial and temporal expression of PORCN is highly dynamic in the developing mouse cochlea. Gene Expr Patterns. 2021 Sep 20;42:119214 |
Wnk1 WNK lysine deficient protein kinase 1 (Synonyms: 6430573H23Rik, EG406236, Hsn2, Prkwnk1) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
2 | J:85860 O'Reilly M, Marshall E, Speirs HJ, Brown RW, WNK1, a Gene within a Novel Blood Pressure Control Pathway, Tissue-Specifically Generates Radically Different Isoforms with and without a Kinase Domain. J Am Soc Nephrol. 2003 Oct;14(10):2447-56 |
Wnt1 wingless-type MMTV integration site family, member 1 (Synonyms: Int-1, Wnt-1) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:306023 Dani N, Herbst RH, McCabe C, Green GS, Kaiser K, Head JP, Cui J, Shipley FB, Jang A, Dionne D, Nguyen L, Rodman C, Riesenfeld SJ, Prochazka J, Prochazkova M, Sedlacek R, Zhang F, Bryja V, Rozenblatt-Rosen O, Habib N, Regev A, Lehtinen MK, A cellular and spatial map of the choroid plexus across brain ventricles and ages. Cell. 2021 May 27;184(11):3056-3074.e21 |
1 | J:335098 Han F, Yang B, Chen Y, Liu L, Cheng X, Huang J, Zhou K, Zhang D, Xu E, Lai M, Lv B, Cheng H, Zhang H, Loss of GLTSCR1 causes congenital heart defects by regulating NPPA transcription. Angiogenesis. 2023 May;26(2):217-232 |
1* | J:8441 Jakobovits A, Shackleford GM, Varmus HE, Martin GR, Two proto-oncogenes implicated in mammary carcinogenesis, int-1 and int-2, are independently regulated during mouse development. Proc Natl Acad Sci U S A. 1986 Oct;83(20):7806-10 |
1 | J:313267 Morenilla-Palao C, Lopez-Cascales MT, Lopez-Atalaya JP, Baeza D, Calvo-Diaz L, Barco A, Herrera E, A Zic2-regulated switch in a noncanonical Wnt/betacatenin pathway is essential for the formation of bilateral circuits. Sci Adv. 2020 Nov;6(46) |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1 | J:306107 Niborski LL, Paces-Fessy M, Ricci P, Bourgeois A, Magalhaes P, Kuzma-Kuzniarska M, Lesaulnier C, Reczko M, Declercq E, Zurbig P, Doucet A, Umbhauer M, Cereghini S, Hnf1b haploinsufficiency differentially affects developmental target genes in a new renal cysts and diabetes mouse model. Dis Model Mech. 2021 May 1;14(5):dmm047498 |
1 | J:91004 Panhuysen M, Vogt Weisenhorn DM, Blanquet V, Brodski C, Heinzmann U, Beisker W, Wurst W, Effects of Wnt1 signaling on proliferation in the developing mid-/hindbrain region. Mol Cell Neurosci. 2004 May;26(1):101-11 |
1* | J:71419 Reddy S, Andl T, Bagasra A, Lu MM, Epstein DJ, Morrisey EE, Millar SE, Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech Dev. 2001 Sep;107(1-2):69-82 |
1 | J:327083 Wang F, Rummukainen P, Pehkonen M, Saamanen AM, Heino TJ, Kiviranta R, Mesenchymal cell-derived Wnt1 signaling regulates subchondral bone remodeling but has no effects on the development of growth plate or articular cartilage in mice. Bone. 2022 Jul 18;163:116497 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Wnt2 wingless-type MMTV integration site family, member 2 (Synonyms: 2610510E18Rik, Int1l1, Irp, m-irp, Mirp, Wnt-2, Wnt2a) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:153098 Goss AM, Tian Y, Tsukiyama T, Cohen ED, Zhou D, Lu MM, Yamaguchi TP, Morrisey EE, Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut. Dev Cell. 2009 Aug;17(2):290-8 |
1* | J:361454 Jasmine, Baraiya DH, T T K, Mandal A, Chakraborty S, Sathish N, Francis CMR, Binoy Joseph D, Epithelial and mesenchymal compartments of the developing bladder and urethra display spatially distinct gene expression patterns. Dev Biol. 2025 Jan 9;520:155-170 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
1* | J:71419 Reddy S, Andl T, Bagasra A, Lu MM, Epstein DJ, Morrisey EE, Millar SE, Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech Dev. 2001 Sep;107(1-2):69-82 |
1* | J:77089 Weidenfeld J, Shu W, Zhang L, Millar SE, Morrisey EE, The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium. J Biol Chem. 2002 Jun 7;277(23):21061-70 |
1 | J:143763 Zhang Y, Singh MK, Degenhardt KR, Lu MM, Bennett J, Yoshida Y, Epstein JA, Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects. Dev Biol. 2009 Jan 1;325(1):82-93 |
Wnt2b wingless-type MMTV integration site family, member 2B (Synonyms: Wnt13) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:239666 Hagglund AC, Jones I, Carlsson L, A novel mouse model of anterior segment dysgenesis (ASD): conditional deletion of Tsc1 disrupts ciliary body and iris development. Dis Model Mech. 2017 Mar 01;10(3):245-257 |
2 | J:254469 Li J, Wang S, Anderson C, Zhao F, Qin Y, Wu D, Wu X, Liu J, He X, Zhao J, Zhang J, Requirement of Smad4 from Ocular Surface Ectoderm for Retinal Development. PLoS One. 2016;11(8):e0159639 |
1 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
2 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
Wnt3 wingless-type MMTV integration site family, member 3 (Synonyms: Int-4, Wnt-3) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:79003 Krylova O, Herreros J, Cleverley KE, Ehler E, Henriquez JP, Hughes SM, Salinas PC, WNT-3, expressed by motoneurons, regulates terminal arborization of neurotrophin-3-responsive spinal sensory neurons. Neuron. 2002 Sep 12;35(6):1043-56 |
1 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
1 | J:18125 Salinas PC, Fletcher C, Copeland NG, Jenkins NA, Nusse R, Maintenance of Wnt-3 expression in Purkinje cells of the mouse cerebellum depends on interactions with granule cells. Development. 1994 May;120(5):1277-86 |
1* | J:3677 Salinas PC, Nusse R, Regional expression of the Wnt-3 gene in the developing mouse forebrain in relationship to diencephalic neuromeres. Mech Dev. 1992 Dec;39(3):151-60 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1 | J:341689 Zhang B, Zhao C, Shen W, Li W, Zheng Y, Kong X, Wang J, Wu X, Zeng T, Liu Y, Zhou Y, KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors. Nat Commun. 2023 Oct 14;14(1):6489 |
1 | J:304122 Zhao X, Rouhiainen A, Li Z, Guo S, Rauvala H, Regulation of Neurogenesis in Mouse Brain by HMGB1. Cells. 2020 Jul 17;9(7):1714 |
Wnt3a wingless-type MMTV integration site family, member 3A (Synonyms: Wnt-3a) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:125693 Hanashima C, Fernandes M, Hebert JM, Fishell G, The role of Foxg1 and dorsal midline signaling in the generation of Cajal-Retzius subtypes. J Neurosci. 2007 Oct 10;27(41):11103-11 |
1* | J:238590 Hayashi K, Ikari T, Sugiyama G, Sugiura T, Ohyama Y, Kumamaru W, Shirasuna K, Mori Y, Involvement of the T-box transcription factor Brachyury in early-stage embryonic mouse salivary gland. Biochem Biophys Res Commun. 2016 Sep 02;477(4):814-9 |
1 | J:166777 Lavado A, Lagutin OV, Chow LM, Baker SJ, Oliver G, Prox1 is required for granule cell maturation and intermediate progenitor maintenance during brain neurogenesis. PLoS Biol. 2010;8(8) |
1* | J:71419 Reddy S, Andl T, Bagasra A, Lu MM, Epstein DJ, Morrisey EE, Millar SE, Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech Dev. 2001 Sep;107(1-2):69-82 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1 | J:341689 Zhang B, Zhao C, Shen W, Li W, Zheng Y, Kong X, Wang J, Wu X, Zeng T, Liu Y, Zhou Y, KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors. Nat Commun. 2023 Oct 14;14(1):6489 |
1* | J:105879 Zhang TJ, Hoffman BG, Ruiz de Algara T, Helgason CD, SAGE reveals expression of Wnt signalling pathway members during mouse prostate development. Gene Expr Patterns. 2006 Mar;6(3):310-24 |
Wnt4 wingless-type MMTV integration site family, member 4 (Synonyms: Wnt-4) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
2* | J:248190 Chen K, Quan H, Chen G, Xiao D, Spatio-temporal expression patterns of Wnt signaling pathway during the development of temporomandibular condylar cartilage. Gene Expr Patterns. 2017 Nov;25-26:149-158 |
1* | J:343078 Diniz F, Ngo NYN, Colon-Leyva M, Edgington-Giordano F, Hilliard S, Zwezdaryk K, Liu J, El-Dahr SS, Tortelote GG, Acetyl-CoA is a key molecule for nephron progenitor cell pool maintenance. Nat Commun. 2023 Nov 25;14(1):7733 |
1 | J:30057 Dudley AT, Lyons KM, Robertson EJ, A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye. Genes Dev. 1995 NOV 15;9(22):2795-2807 |
1 | J:152858 Garcia-Ortiz JE, Pelosi E, Omari S, Nedorezov T, Piao Y, Karmazin J, Uda M, Cao A, Cole SW, Forabosco A, Schlessinger D, Ottolenghi C, Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Dev Biol. 2009;9:36 |
1* | J:10971 Gavin BJ, McMahon JA, McMahon AP, Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 1990 Dec;4(12B):2319-32 |
1 | J:187047 Gerber SD, Amann R, Wyder S, Trueb B, Comparison of the gene expression profiles from normal and Fgfrl1 deficient mouse kidneys reveals downstream targets of Fgfrl1 signaling. PLoS One. 2012;7(3):e33457 |
1 | J:153202 Gerber SD, Steinberg F, Beyeler M, Villiger PM, Trueb B, The murine Fgfrl1 receptor is essential for the development of the metanephric kidney. Dev Biol. 2009 Nov 1;335(1):106-19 |
1 | J:101176 Grieshammer U, Cebrian C, Ilagan R, Meyers E, Herzlinger D, Martin GR, FGF8 is required for cell survival at distinct stages of nephrogenesis and for regulation of gene expression in nascent nephrons. Development. 2005 Sep;132(17):3847-57 |
1 | J:315113 Hafner R, Bohnenpoll T, Rudat C, Schultheiss TM, Kispert A, Fgfr2 is required for the expansion of the early adrenocortical primordium. Mol Cell Endocrinol. 2015 Sep 15;413:168-77 |
1 | J:108713 Itaranta P, Chi L, Seppanen T, Niku M, Tuukkanen J, Peltoketo H, Vainio S, Wnt-4 signaling is involved in the control of smooth muscle cell fate via Bmp-4 in the medullary stroma of the developing kidney. Dev Biol. 2006 May 15;293(2):473-83 |
1* | J:168597 Kashimada K, Pelosi E, Chen H, Schlessinger D, Wilhelm D, Koopman P, FOXL2 and BMP2 act cooperatively to regulate follistatin gene expression during ovarian development. Endocrinology. 2011 Jan;152(1):272-80 |
1 | J:199204 Kiyohashi K, Kakinuma S, Kamiya A, Sakamoto N, Nitta S, Yamanaka H, Yoshino K, Fujiki J, Murakawa M, Kusano-Kitazume A, Shimizu H, Okamoto R, Azuma S, Nakagawa M, Asahina Y, Tanimizu N, Kikuchi A, Nakauchi H, Watanabe M, Wnt5a signaling mediates biliary differentiation of fetal hepatic stem/progenitor cells in mice. Hepatology. 2013 Jun;57(6):2502-13 |
1 | J:321428 Kruber P, Angay O, Winkler A, Bosl MR, Kneitz S, Heinze KG, Gessler M, Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation. Int J Cancer. 2019 Mar 15;144(6):1391-1400 |
1 | J:188148 Landin MA, Shabestari M, Babaie E, Reseland JE, Osmundsen H, Gene Expression Profiling during Murine Tooth Development. Front Genet. 2012;3:139 |
1 | J:246806 Li Y, Zhang L, Hu Y, Chen M, Han F, Qin Y, Chen M, Cui X, Duo S, Tang F, Gao F, beta-Catenin directs the transformation of testis Sertoli cells to ovarian granulosa-like cells by inducing Foxl2 expression. J Biol Chem. 2017 Oct 27;292(43):17577-17586 |
1* | J:70601 Lickert H, Kispert A, Kutsch S, Kemler R, Expression patterns of Wnt genes in mouse gut development. Mech Dev. 2001 Jul;105(1-2):181-4 |
2 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1 | J:321068 Maimets M, Pedersen MT, Guiu J, Dreier J, Thodberg M, Antoku Y, Schweiger PJ, Rib L, Bressan RB, Miao Y, Garcia KC, Sandelin A, Serup P, Jensen KB, Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling. Nat Commun. 2022 Feb 7;13(1):715 |
1* | J:67157 McCright B, Gao X, Shen L, Lozier J, Lan Y, Maguire M, Herzlinger D, Weinmaster G, Jiang R, Gridley T, Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development. 2001 Feb;128(4):491-502 |
1 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
2 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1 | J:120229 Narlis M, Grote D, Gaitan Y, Boualia SK, Bouchard M, Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney. J Am Soc Nephrol. 2007 Apr;18(4):1121-9 |
1* | J:311540 Oliver BL, Young CA, Munnamalai V, Spatial and temporal expression of PORCN is highly dynamic in the developing mouse cochlea. Gene Expr Patterns. 2021 Sep 20;42:119214 |
1* | J:21884 Stark K, Vainio S, Vassileva G, McMahon AP, Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature. 1994 Dec 15;372(6507):679-83 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1 | J:75544 Surendran K, McCaul SP, Simon TC, A role for Wnt-4 in renal fibrosis. Am J Physiol Renal Physiol. 2002 Mar;282(3):F431-41 |
1 | J:332922 Venkata VD, Jamaluddin MFB, Goad J, Drury HR, Tadros MA, Lim R, Karakoti A, O'Sullivan R, Ius Y, Jaaback K, Nahar P, Tanwar PS, Development and characterization of human fetal female reproductive tract organoids to understand Mullerian duct anomalies. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2118054119 |
1 | J:356085 Wang J, Tian GG, Zheng Z, Li B, Xing Q, Wu J, Comprehensive Transcriptomic Analysis of Mouse Gonadal Development Involving Sexual Differentiation, Meiosis and Gametogenesis. Biol Proced Online. 2019;21:20 |
1* | J:105879 Zhang TJ, Hoffman BG, Ruiz de Algara T, Helgason CD, SAGE reveals expression of Wnt signalling pathway members during mouse prostate development. Gene Expr Patterns. 2006 Mar;6(3):310-24 |
Wnt5a wingless-type MMTV integration site family, member 5A (Synonyms: 8030457G12Rik, Wnt-5a) | |
Results | Reference |
1 | J:313969 Alcantara MC, Suzuki K, Acebedo AR, Sakamoto Y, Nishita M, Minami Y, Kikuchi A, Yamada G, Stage-dependent function of Wnt5a during male external genitalia development. Congenit Anom (Kyoto). 2021 Nov;61(6):212-219 |
1* | J:142714 Allgeier SH, Lin TM, Vezina CM, Moore RW, Fritz WA, Chiu SY, Zhang C, Peterson RE, WNT5A selectively inhibits mouse ventral prostate development. Dev Biol. 2008 Dec 1;324(1):10-7 |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:149814 Bodmer D, Levine-Wilkinson S, Richmond A, Hirsh S, Kuruvilla R, Wnt5a mediates nerve growth factor-dependent axonal branching and growth in developing sympathetic neurons. J Neurosci. 2009 Jun 10;29(23):7569-81 |
1* | J:177568 Cai J, Mutoh N, Shin JO, Tani-Ishii N, Ohshima H, Cho SW, Jung HS, Wnt5a plays a crucial role in determining tooth size during murine tooth development. Cell Tissue Res. 2011 Sep;345(3):367-77 |
1 | J:185786 Chawengsaksophak K, Svingen T, Ng ET, Epp T, Spiller CM, Clark C, Cooper H, Koopman P, Loss of Wnt5a disrupts primordial germ cell migration and male sexual development in mice. Biol Reprod. 2012 Jan;86(1):1-12 |
1 | J:325251 Chen A, Liao S, Cheng M, Ma K, Wu L, Lai Y, Qiu X, Yang J, Xu J, Hao S, Wang X, Lu H, Chen X, Liu X, Huang X, Li Z, Hong Y, Jiang Y, Peng J, Liu S, Shen M, Liu C, Li Q, Yuan Y, Wei X, Zheng H, Feng W, Wang Z, Liu Y, Wang Z, Yang Y, Xiang H, Han L, Qin B, Guo P, Lai G, Munoz-Canoves P, Maxwell PH, Thiery JP, Wu QF, Zhao F, Chen B, Li M, Dai X, Wang S, Kuang H, Hui J, Wang L, Fei JF, Wang O, Wei X, Lu H, Wang B, Liu S, Gu Y, Ni M, Zhang W, Mu F, Yin Y, Yang H, Lisby M, Cornall RJ, Mulder J, Uhlen M, Esteban MA, Li Y, Liu L, Xu X, Wang J, Spatiotemporal transcriptomic atlas of mouse organogenesis using DNA nanoball-patterned arrays. Cell. 2022 May 12;185(10):1777-1792.e21 |
2* | J:248190 Chen K, Quan H, Chen G, Xiao D, Spatio-temporal expression patterns of Wnt signaling pathway during the development of temporomandibular condylar cartilage. Gene Expr Patterns. 2017 Nov;25-26:149-158 |
1 | J:312814 Fernandez Vallone V, Leprovots M, Ribatallada-Soriano D, Gerbier R, Lefort A, Libert F, Vassart G, Garcia MI, LGR5 controls extracellular matrix production by stem cells in the developing intestine. EMBO Rep. 2020 Jul 3;21(7):e49224 |
2 | J:163382 Foronjy R, Imai K, Shiomi T, Mercer B, Sklepkiewicz P, Thankachen J, Bodine P, D'Armiento J, The divergent roles of secreted frizzled related protein-1 (SFRP1) in lung morphogenesis and emphysema. Am J Pathol. 2010 Aug;177(2):598-607 |
1 | J:93083 Fraidenraich D, Stillwell E, Romero E, Wilkes D, Manova K, Basson CT, Benezra R, Rescue of cardiac defects in id knockout embryos by injection of embryonic stem cells. Science. 2004 Oct 8;306(5694):247-52 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1* | J:10971 Gavin BJ, McMahon JA, McMahon AP, Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 1990 Dec;4(12B):2319-32 |
1* | J:48569 Grove EA, Tole S, Limon J, Yip L, Ragsdale CW, The hem of the embryonic cerebral cortex is defined by the expression of multiple Wnt genes and is compromised in Gli3-deficient mice. Development. 1998 Jun;125(12):2315-25 |
1* | J:262280 He L, Lei M, Xing Y, Li Y, Hu C, Chen P, Lian X, Yang T, Liu W, Yang L, Gsdma3 regulates hair follicle differentiation via Wnt5a-mediated non-canonical Wnt signaling pathway. Oncotarget. 2017 Nov 21;8(59):100269-100279 |
1 | J:273296 Kaiser K, Gyllborg D, Prochazka J, Salasova A, Kompanikova P, Molina FL, Laguna-Goya R, Radaszkiewicz T, Harnos J, Prochazkova M, Potesil D, Barker RA, Casado AG, Zdrahal Z, Sedlacek R, Arenas E, Villaescusa JC, Bryja V, WNT5A is transported via lipoprotein particles in the cerebrospinal fluid to regulate hindbrain morphogenesis. Nat Commun. 2019 Apr 2;10(1):1498 |
4 | J:308827 Kaiser K, Jang A, Kompanikova P, Lun MP, Prochazka J, Machon O, Dani N, Prochazkova M, Laurent B, Gyllborg D, van Amerongen R, Fame RM, Gupta S, Wu F, Barker RA, Bukova I, Sedlacek R, Kozmik Z, Arenas E, Lehtinen MK, Bryja V, MEIS-WNT5A axis regulates development of fourth ventricle choroid plexus. Development. 2021 May 15;148(10):dev192054 |
1* | J:205338 Kuss P, Kraft K, Stumm J, Ibrahim D, Vallecillo-Garcia P, Mundlos S, Stricker S, Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A. Dev Biol. 2014 Jan 1;385(1):83-93 |
1* | J:70601 Lickert H, Kispert A, Kutsch S, Kemler R, Expression patterns of Wnt genes in mouse gut development. Mech Dev. 2001 Jul;105(1-2):181-4 |
1* | J:167829 Lin M, Li L, Liu C, Liu H, He F, Yan F, Zhang Y, Chen Y, Wnt5a regulates growth, patterning, and odontoblast differentiation of developing mouse tooth. Dev Dyn. 2011 Feb;240(2):432-40 |
1 | J:179217 Liu HX, Grosse AS, Iwatsuki K, Mishina Y, Gumucio DL, Mistretta CM, Separate and distinctive roles for Wnt5a in tongue, lingual tissue and taste papilla development. Dev Biol. 2012 Jan 1;361(1):39-56 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
1 | J:193842 Lu C, Wan Y, Cao J, Zhu X, Yu J, Zhou R, Yao Y, Zhang L, Zhao H, Li H, Zhao J, He L, Ma G, Yang X, Yao Z, Guo X, Wnt-mediated reciprocal regulation between cartilage and bone development during endochondral ossification. Bone. 2013 Apr;53(2):566-74 |
1 | J:195172 Ludtke TH, Farin HF, Rudat C, Schuster-Gossler K, Petry M, Barnett P, Christoffels VM, Kispert A, Tbx2 controls lung growth by direct repression of the cell cycle inhibitor genes Cdkn1a and Cdkn1b. PLoS Genet. 2013 Jan;9(1):e1003189 |
1 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
1 | J:313267 Morenilla-Palao C, Lopez-Cascales MT, Lopez-Atalaya JP, Baeza D, Calvo-Diaz L, Barco A, Herrera E, A Zic2-regulated switch in a noncanonical Wnt/betacatenin pathway is essential for the formation of bilateral circuits. Sci Adv. 2020 Nov;6(46) |
1 | J:158526 Naillat F, Prunskaite-Hyyrylainen R, Pietila I, Sormunen R, Jokela T, Shan J, Vainio SJ, Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development. Hum Mol Genet. 2010 Apr 15;19(8):1539-50 |
2 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1* | J:311540 Oliver BL, Young CA, Munnamalai V, Spatial and temporal expression of PORCN is highly dynamic in the developing mouse cochlea. Gene Expr Patterns. 2021 Sep 20;42:119214 |
1* | J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20 |
2 | J:122585 Qian D, Jones C, Rzadzinska A, Mark S, Zhang X, Steel KP, Dai X, Chen P, Wnt5a functions in planar cell polarity regulation in mice. Dev Biol. 2007 Jun 1;306(1):121-33 |
1* | J:71419 Reddy S, Andl T, Bagasra A, Lu MM, Epstein DJ, Morrisey EE, Millar SE, Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech Dev. 2001 Sep;107(1-2):69-82 |
1* | J:131546 Rinn JL, Wang JK, Allen N, Brugmann SA, Mikels AJ, Liu H, Ridky TW, Stadler HS, Nusse R, Helms JA, Chang HY, A dermal HOX transcriptional program regulates site-specific epidermal fate. Genes Dev. 2008 Feb 1;22(3):303-7 |
1* | J:196291 Ryu YK, Collins SE, Ho HY, Zhao H, Kuruvilla R, An autocrine Wnt5a-Ror signaling loop mediates sympathetic target innervation. Dev Biol. 2013 May 1;377(1):79-89 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1* | J:153152 Tai CC, Sala FG, Ford HR, Wang KS, Li C, Minoo P, Grikscheit TC, Bellusci S, Wnt5a knock-out mouse as a new model of anorectal malformation. J Surg Res. 2009 Oct;156(2):278-82 |
3 | J:283400 Wuelling M, Schneider S, Schrother VA, Waterkamp C, Hoffmann D, Vortkamp A, Wnt5a is a transcriptional target of Gli3 and Trps1 at the onset of chondrocyte hypertrophy. Dev Biol. 2020 Jan 1;457(1):104-118 |
1* | J:119549 Yang XY, Yang TT, Schubert W, Factor SM, Chow CW, Dosage-dependent transcriptional regulation by the calcineurin/NFAT signaling in developing myocardium transition. Dev Biol. 2007 Mar 15;303(2):825-37 |
1 | J:341689 Zhang B, Zhao C, Shen W, Li W, Zheng Y, Kong X, Wang J, Wu X, Zeng T, Liu Y, Zhou Y, KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors. Nat Commun. 2023 Oct 14;14(1):6489 |
Wnt5b wingless-type MMTV integration site family, member 5B (Synonyms: Wnt-5b) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1* | J:10971 Gavin BJ, McMahon JA, McMahon AP, Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 1990 Dec;4(12B):2319-32 |
1* | J:205338 Kuss P, Kraft K, Stumm J, Ibrahim D, Vallecillo-Garcia P, Mundlos S, Stricker S, Regulation of cell polarity in the cartilage growth plate and perichondrium of metacarpal elements by HOXD13 and WNT5A. Dev Biol. 2014 Jan 1;385(1):83-93 |
1* | J:70601 Lickert H, Kispert A, Kutsch S, Kemler R, Expression patterns of Wnt genes in mouse gut development. Mech Dev. 2001 Jul;105(1-2):181-4 |
1 | J:193842 Lu C, Wan Y, Cao J, Zhu X, Yu J, Zhou R, Yao Y, Zhang L, Zhao H, Li H, Zhao J, He L, Ma G, Yang X, Yao Z, Guo X, Wnt-mediated reciprocal regulation between cartilage and bone development during endochondral ossification. Bone. 2013 Apr;53(2):566-74 |
1 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
1* | J:71419 Reddy S, Andl T, Bagasra A, Lu MM, Epstein DJ, Morrisey EE, Millar SE, Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech Dev. 2001 Sep;107(1-2):69-82 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1 | J:341689 Zhang B, Zhao C, Shen W, Li W, Zheng Y, Kong X, Wang J, Wu X, Zeng T, Liu Y, Zhou Y, KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors. Nat Commun. 2023 Oct 14;14(1):6489 |
Wnt6 wingless-type MMTV integration site family, member 6 (Synonyms: Wnt-6) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1* | J:10971 Gavin BJ, McMahon JA, McMahon AP, Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 1990 Dec;4(12B):2319-32 |
2 | J:353381 Kostic L, Leung C, Ahmad Murad K, Kancheva S, Perna S, Lee B, Barker N, Lgr5 marks stem/progenitor cells contributing to epithelial and muscle development in the mouse esophagus. Nat Commun. 2024 Aug 21;15(1):7145 |
1 | J:188148 Landin MA, Shabestari M, Babaie E, Reseland JE, Osmundsen H, Gene Expression Profiling during Murine Tooth Development. Front Genet. 2012;3:139 |
1* | J:70601 Lickert H, Kispert A, Kutsch S, Kemler R, Expression patterns of Wnt genes in mouse gut development. Mech Dev. 2001 Jul;105(1-2):181-4 |
1 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
1 | J:341689 Zhang B, Zhao C, Shen W, Li W, Zheng Y, Kong X, Wang J, Wu X, Zeng T, Liu Y, Zhou Y, KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors. Nat Commun. 2023 Oct 14;14(1):6489 |
Wnt7a wingless-type MMTV integration site family, member 7A (Synonyms: tw, Wnt-7a) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:217500 Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D, Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60 |
1* | J:10971 Gavin BJ, McMahon JA, McMahon AP, Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 1990 Dec;4(12B):2319-32 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
2 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
1 | J:135432 Nightingale SS, Western P, Hutson JM, The migrating gubernaculum grows like a 'limb bud'. J Pediatr Surg. 2008 Feb;43(2):387-90 |
1* | J:311540 Oliver BL, Young CA, Munnamalai V, Spatial and temporal expression of PORCN is highly dynamic in the developing mouse cochlea. Gene Expr Patterns. 2021 Sep 20;42:119214 |
1* | J:71419 Reddy S, Andl T, Bagasra A, Lu MM, Epstein DJ, Morrisey EE, Millar SE, Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech Dev. 2001 Sep;107(1-2):69-82 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1 | J:332922 Venkata VD, Jamaluddin MFB, Goad J, Drury HR, Tadros MA, Lim R, Karakoti A, O'Sullivan R, Ius Y, Jaaback K, Nahar P, Tanwar PS, Development and characterization of human fetal female reproductive tract organoids to understand Mullerian duct anomalies. Proc Natl Acad Sci U S A. 2022 Jul 26;119(30):e2118054119 |
Wnt7b wingless-type MMTV integration site family, member 7B (Synonyms: Wnt-7b) | |
Results | Reference |
1 | J:353312 Adutwum-Ofosu K, Magnani D, Theil T, Price DJ, Fotaki, The molecular and cellular signatures of the mouse eminentia thalami support its role as a signalling centre in the developing forebrain. Brain Struct Funct. 2016;221(7):3709-27 |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:188176 Caparros-Martin JA, Valencia M, Reytor E, Pacheco M, Fernandez M, Perez-Aytes A, Gean E, Lapunzina P, Peters H, Goodship JA, Ruiz-Perez VL, The ciliary Evc/Evc2 complex interacts with Smo and controls Hedgehog pathway activity in chondrocytes by regulating Sufu/Gli3 dissociation and Gli3 trafficking in primary cilia. Hum Mol Genet. 2013 Jan 1;22(1):124-39 |
1 | J:217500 Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D, Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60 |
1 | J:163382 Foronjy R, Imai K, Shiomi T, Mercer B, Sklepkiewicz P, Thankachen J, Bodine P, D'Armiento J, The divergent roles of secreted frizzled related protein-1 (SFRP1) in lung morphogenesis and emphysema. Am J Pathol. 2010 Aug;177(2):598-607 |
2* | J:174497 Funatsu N, Inoue T, Nakamura S, Gene expression analysis of the late embryonic mouse cerebral cortex using DNA microarray: identification of several region- and layer-specific genes. Cereb Cortex. 2004 Sep;14(9):1031-44 |
1* | J:10971 Gavin BJ, McMahon JA, McMahon AP, Expression of multiple novel Wnt-1/int-1-related genes during fetal and adult mouse development. Genes Dev. 1990 Dec;4(12B):2319-32 |
1* | J:260471 Gerhardt B, Leesman L, Burra K, Snowball J, Rosenzweig R, Guzman N, Ambalavanan M, Sinner D, Notum attenuates Wnt/beta-catenin signaling to promote tracheal cartilage patterning. Dev Biol. 2018 Apr 1;436(1):14-27 |
1 | J:263240 Kandyba E, Kobielak K, Wnt7b is an important intrinsic regulator of hair follicle stem cell homeostasis and hair follicle cycling. Stem Cells. 2014 Apr;32(4):886-901 |
1 | J:178118 Li Q, Bian S, Hong J, Kawase-Koga Y, Zhu E, Zheng Y, Yang L, Sun T, Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development. PLoS One. 2011;6(10):e26000 |
1 | J:194480 Ma S, Kwon HJ, Johng H, Zang K, Huang Z, Radial glial neural progenitors regulate nascent brain vascular network stabilization via inhibition of Wnt signaling. PLoS Biol. 2013 Jan;11(1):e1001469 |
1 | J:294016 Medina-Martinez O, Haller M, Rosenfeld JA, O'Neill MA, Lamb DJ, Jamrich M, The transcription factor Maz is essential for normal eye development. Dis Model Mech. 2020 Aug 18;13(8):dmm044412 |
2 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
1* | J:311540 Oliver BL, Young CA, Munnamalai V, Spatial and temporal expression of PORCN is highly dynamic in the developing mouse cochlea. Gene Expr Patterns. 2021 Sep 20;42:119214 |
1 | J:179841 Pacheco M, Valencia M, Caparros-Martin JA, Mulero F, Goodship JA, Ruiz-Perez VL, Evc works in chondrocytes and osteoblasts to regulate multiple aspects of growth plate development in the appendicular skeleton and cranial base. Bone. 2012 Jan;50(1):28-41 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:361958 Straube P, Beckers A, Jany UWH, Bergmann F, Ludtke TH, Rudat C, Trowe MO, Peters I, Klopf MG, Mamo TM, Kispert A, Interplay of SHH, WNT and BMP4 signaling regulates the development of the lamina propria in the murine ureter. Development. 2025 Feb 1;152(3) |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
2 | J:311811 Trowe MO, Airik R, Weiss AC, Farin HF, Foik AB, Bettenhausen E, Schuster-Gossler K, Taketo MM, Kispert A, Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter. Development. 2012 Sep;139(17):3099-108 |
1* | J:77089 Weidenfeld J, Shu W, Zhang L, Millar SE, Morrisey EE, The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium. J Biol Chem. 2002 Jun 7;277(23):21061-70 |
1* | J:146829 Yamada W, Nagao K, Horikoshi K, Fujikura A, Ikeda E, Inagaki Y, Kakitani M, Tomizuka K, Miyazaki H, Suda T, Takubo K, Craniofacial malformation in R-spondin2 knockout mice. Biochem Biophys Res Commun. 2009 Apr 10;381(3):453-8 |
1 | J:281878 Yook C, Kim K, Kim D, Kang H, Kim SG, Kim E, Kim SY, A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice. Front Mol Neurosci. 2019;12:241 |
1 | J:341689 Zhang B, Zhao C, Shen W, Li W, Zheng Y, Kong X, Wang J, Wu X, Zeng T, Liu Y, Zhou Y, KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors. Nat Commun. 2023 Oct 14;14(1):6489 |
Wnt8a wingless-type MMTV integration site family, member 8A (Synonyms: Stra11) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1* | J:330442 Garcia-Padilla C, Dominguez JN, Lodde V, Munk R, Abdelmohsen K, Gorospe M, Jimenez-Sabado V, Ginel A, Hove-Madsen L, Aranega AE, Franco D, Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation. FASEB J. 2022 Jan;36(1):e22051 |
1* | J:71419 Reddy S, Andl T, Bagasra A, Lu MM, Epstein DJ, Morrisey EE, Millar SE, Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech Dev. 2001 Sep;107(1-2):69-82 |
1* | J:105879 Zhang TJ, Hoffman BG, Ruiz de Algara T, Helgason CD, SAGE reveals expression of Wnt signalling pathway members during mouse prostate development. Gene Expr Patterns. 2006 Mar;6(3):310-24 |
Wnt8b wingless-type MMTV integration site family, member 8B | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
2 | J:315293 Kumamoto T, Toma K, Gunadi, McKenna WL, Kasukawa T, Katzman S, Chen B, Hanashima C, Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013 Mar 28;3(3):931-45 |
1* | J:71419 Reddy S, Andl T, Bagasra A, Lu MM, Epstein DJ, Morrisey EE, Millar SE, Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech Dev. 2001 Sep;107(1-2):69-82 |
1* | J:104160 Tole S, Gutin G, Bhatnagar L, Remedios R, Hebert JM, Development of midline cell types and commissural axon tracts requires Fgfr1 in the cerebrum. Dev Biol. 2006 Jan 1;289(1):141-51 |
1 | J:341689 Zhang B, Zhao C, Shen W, Li W, Zheng Y, Kong X, Wang J, Wu X, Zeng T, Liu Y, Zhou Y, KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors. Nat Commun. 2023 Oct 14;14(1):6489 |
1* | J:105879 Zhang TJ, Hoffman BG, Ruiz de Algara T, Helgason CD, SAGE reveals expression of Wnt signalling pathway members during mouse prostate development. Gene Expr Patterns. 2006 Mar;6(3):310-24 |
Wnt9a wingless-type MMTV integration site family, member 9A (Synonyms: Wnt14) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
2* | J:248190 Chen K, Quan H, Chen G, Xiao D, Spatio-temporal expression patterns of Wnt signaling pathway during the development of temporomandibular condylar cartilage. Gene Expr Patterns. 2017 Nov;25-26:149-158 |
1 | J:160493 Dy P, Smits P, Silvester A, Penzo-Mendez A, Dumitriu B, Han Y, de la Motte CA, Kingsley DM, Lefebvre V, Synovial joint morphogenesis requires the chondrogenic action of Sox5 and Sox6 in growth plate and articular cartilage. Dev Biol. 2010 May 15;341(2):346-59 |
2 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:134924 Spagnoli A, O'Rear L, Chandler RL, Granero-Molto F, Mortlock DP, Gorska AE, Weis JA, Longobardi L, Chytil A, Shimer K, Moses HL, TGF-beta signaling is essential for joint morphogenesis. J Cell Biol. 2007 Jun 18;177(6):1105-17 |
1 | J:341689 Zhang B, Zhao C, Shen W, Li W, Zheng Y, Kong X, Wang J, Wu X, Zeng T, Liu Y, Zhou Y, KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors. Nat Commun. 2023 Oct 14;14(1):6489 |
Wnt9b wingless-type MMTV integration site family, member 9B (Synonyms: clf, clf1, Wnt14b, Wnt15) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:153202 Gerber SD, Steinberg F, Beyeler M, Villiger PM, Trueb B, The murine Fgfrl1 receptor is essential for the development of the metanephric kidney. Dev Biol. 2009 Nov 1;335(1):106-19 |
1 | J:298947 Liu H, Hilliard S, Kelly E, Chen CH, Saifudeen Z, El-Dahr SS, The polycomb proteins EZH1 and EZH2 co-regulate chromatin accessibility and nephron progenitor cell lifespan in mice. J Biol Chem. 2020 Aug 14;295(33):11542-11558 |
1 | J:296151 Liu J, Chanumolu SK, White KM, Albahrani M, Otu HH, Nawshad A, Transcriptional analysis of cleft palate in TGFbeta3 mutant mice. Sci Rep. 2020 Sep 10;10(1):14940 |
2 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
1 | J:347984 Naillat F, Deshar G, Hankkila A, Rak-Raszewska A, Sharma A, Prunskaite-Hyyrylainen R, Railo A, Shan J, Vainio SJ, Calcium signaling induces partial EMT and renal fibrosis in a Wnt4(mCherry) knock-in mouse model. Biochim Biophys Acta Mol Basis Dis. 2024 Apr 21;1870(5):167180 |
2* | J:81512 Qian J, Jiang Z, Li M, Heaphy P, Liu YH, Shackleford GM, Mouse Wnt9b transforming activity, tissue-specific expression, and evolution. Genomics. 2003 Jan;81(1):34-46 |
1 | J:264384 Ramalingam H, Fessler AR, Das A, Valerius MT, Basta J, Robbins L, Brown AC, Oxburgh L, McMahon AP, Rauchman M, Carroll TJ, Disparate levels of beta-catenin activity determine nephron progenitor cell fate. Dev Biol. 2018 Aug 1;440(1):13-21 |
1* | J:71419 Reddy S, Andl T, Bagasra A, Lu MM, Epstein DJ, Morrisey EE, Millar SE, Characterization of Wnt gene expression in developing and postnatal hair follicles and identification of Wnt5a as a target of Sonic hedgehog in hair follicle morphogenesis. Mech Dev. 2001 Sep;107(1-2):69-82 |
1 | J:138247 Saburi S, Hester I, Fischer E, Pontoglio M, Eremina V, Gessler M, Quaggin SE, Harrison R, Mount R, McNeill H, Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nat Genet. 2008 Aug;40(8):1010-5 |
2 | J:311811 Trowe MO, Airik R, Weiss AC, Farin HF, Foik AB, Bettenhausen E, Schuster-Gossler K, Taketo MM, Kispert A, Canonical Wnt signaling regulates smooth muscle precursor development in the mouse ureter. Development. 2012 Sep;139(17):3099-108 |
Wnt10a wingless-type MMTV integration site family, member 10A | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1* | J:36010 Wang J, Shackleford GM, Murine Wnt10a and Wnt10b: cloning and expression in developing limbs, face and skin of embryos and in adults. Oncogene. 1996 Oct 3;13(7):1537-44 |
1 | J:341689 Zhang B, Zhao C, Shen W, Li W, Zheng Y, Kong X, Wang J, Wu X, Zeng T, Liu Y, Zhou Y, KDM2B regulates hippocampal morphogenesis by transcriptionally silencing Wnt signaling in neural progenitors. Nat Commun. 2023 Oct 14;14(1):6489 |
Wnt10b wingless-type MMTV integration site family, member 10B (Synonyms: Wnt12) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:111051 Cui CY, Hashimoto T, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Ectodysplasin regulates the lymphotoxin-beta pathway for hair differentiation. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9142-7 |
1 | J:217500 Cui CY, Yin M, Sima J, Childress V, Michel M, Piao Y, Schlessinger D, Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60 |
2 | J:163382 Foronjy R, Imai K, Shiomi T, Mercer B, Sklepkiewicz P, Thankachen J, Bodine P, D'Armiento J, The divergent roles of secreted frizzled related protein-1 (SFRP1) in lung morphogenesis and emphysema. Am J Pathol. 2010 Aug;177(2):598-607 |
1 | J:139508 Gao J, DeRouen MC, Chen CH, Nguyen M, Nguyen NT, Ido H, Harada K, Sekiguchi K, Morgan BA, Miner JH, Oro AE, Marinkovich MP, Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. Genes Dev. 2008 Aug 1;22(15):2111-24 |
1 | J:119729 Iwatsuki K, Liu HX, Gronder A, Singer MA, Lane TF, Grosschedl R, Mistretta CM, Margolskee RF, Wnt signaling interacts with Shh to regulate taste papilla development. Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2253-8 |
1* | J:187370 Keil KP, Mehta V, Abler LL, Joshi PS, Schmitz CT, Vezina CM, Visualization and quantification of mouse prostate development by in situ hybridization. Differentiation. 2012 Oct;84(3):232-9 |
2* | J:44244 Lane TF, Leder P, Wnt-10b directs hypermorphic development and transformation in mammary glands of male and female mice. Oncogene. 1997 Oct;15(18):2133-44 |
1 | J:294283 Liang Q, Zheng Q, Zuo Y, Chen Y, Ma J, Ni P, Cheng J, SENP2 Suppresses Necdin Expression to Promote Brown Adipocyte Differentiation. Cell Rep. 2019 Aug 20;28(8):2004-2011.e4 |
1 | J:130228 Liu F, Chu EY, Watt B, Zhang Y, Gallant NM, Andl T, Yang SH, Lu MM, Piccolo S, Schmidt-Ullrich R, Taketo MM, Morrisey EE, Atit R, Dlugosz AA, Millar SE, Wnt/beta-catenin signaling directs multiple stages of tooth morphogenesis. Dev Biol. 2008 Jan 1;313(1):210-24 |
1 | J:193842 Lu C, Wan Y, Cao J, Zhu X, Yu J, Zhou R, Yao Y, Zhang L, Zhao H, Li H, Zhao J, He L, Ma G, Yang X, Yao Z, Guo X, Wnt-mediated reciprocal regulation between cartilage and bone development during endochondral ossification. Bone. 2013 Apr;53(2):566-74 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1 | J:144194 Suzuki K, Yamaguchi Y, Villacorte M, Mihara K, Akiyama M, Shimizu H, Taketo MM, Nakagata N, Tsukiyama T, Yamaguchi TP, Birchmeier W, Kato S, Yamada G, Embryonic hair follicle fate change by augmented {beta}-catenin through Shh and Bmp signaling. Development. 2009 Feb;136(3):367-72 |
2* | J:36010 Wang J, Shackleford GM, Murine Wnt10a and Wnt10b: cloning and expression in developing limbs, face and skin of embryos and in adults. Oncogene. 1996 Oct 3;13(7):1537-44 |
Wnt11 wingless-type MMTV integration site family, member 11 | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:131874 Di-Poi N, Zakany J, Duboule D, Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development. PLoS Genet. 2007 Dec 21;3(12):e232 |
1* | J:330442 Garcia-Padilla C, Dominguez JN, Lodde V, Munk R, Abdelmohsen K, Gorospe M, Jimenez-Sabado V, Ginel A, Hove-Madsen L, Aranega AE, Franco D, Identification of atrial-enriched lncRNA Walras linked to cardiomyocyte cytoarchitecture and atrial fibrillation. FASEB J. 2022 Jan;36(1):e22051 |
1 | J:153202 Gerber SD, Steinberg F, Beyeler M, Villiger PM, Trueb B, The murine Fgfrl1 receptor is essential for the development of the metanephric kidney. Dev Biol. 2009 Nov 1;335(1):106-19 |
1* | J:199186 Juuri E, Saito K, Lefebvre S, Michon F, Establishment of crown-root domain borders in mouse incisor. Gene Expr Patterns. 2013 Oct;13(7):255-64 |
2* | J:36828 Kispert A, Vainio S, Shen L, Rowitch DH, McMahon AP, Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips. Development. 1996 Nov;122(11):3627-37 |
1* | J:70601 Lickert H, Kispert A, Kutsch S, Kemler R, Expression patterns of Wnt genes in mouse gut development. Mech Dev. 2001 Jul;105(1-2):181-4 |
1 | J:193842 Lu C, Wan Y, Cao J, Zhu X, Yu J, Zhou R, Yao Y, Zhang L, Zhao H, Li H, Zhao J, He L, Ma G, Yang X, Yao Z, Guo X, Wnt-mediated reciprocal regulation between cartilage and bone development during endochondral ossification. Bone. 2013 Apr;53(2):566-74 |
1 | J:313267 Morenilla-Palao C, Lopez-Cascales MT, Lopez-Atalaya JP, Baeza D, Calvo-Diaz L, Barco A, Herrera E, A Zic2-regulated switch in a noncanonical Wnt/betacatenin pathway is essential for the formation of bilateral circuits. Sci Adv. 2020 Nov;6(46) |
1 | J:266862 Morosan-Puopolo G, Balakrishnan-Renuka A, Yusuf F, Chen J, Dai F, Zoidl G, Ludtke TH, Kispert A, Theiss C, Abdelsabour-Khalaf M, Brand-Saberi B, Wnt11 is required for oriented migration of dermogenic progenitor cells from the dorsomedial lip of the avian dermomyotome. PLoS One. 2014;9(3):e92679 |
1 | J:235788 Nagy II, Xu Q, Naillat F, Ali N, Miinalainen I, Samoylenko A, Vainio SJ, Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis. BMC Dev Biol. 2016 Aug 31;16(1):30 |
2 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
1* | J:281425 Nakaniwa M, Kawasaki M, Kawasaki K, Yamada A, Meguro F, Takeyasu M, Ohazama A, Primary cilia in murine palatal rugae development. Gene Expr Patterns. 2019 Jun 19;34:119062 |
1 | J:120229 Narlis M, Grote D, Gaitan Y, Boualia SK, Bouchard M, Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney. J Am Soc Nephrol. 2007 Apr;18(4):1121-9 |
1* | J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20 |
1* | J:332639 Rinta-Jaskari MM, Naillat F, Ruotsalainen HJ, Koivunen JT, Sasaki T, Pietila I, Elamaa HP, Kaur I, Manninen A, Vainio SJ, Pihlajaniemi TA, Temporally and Spatially Regulated Collagen XVIII Isoforms Are Involved in Ureteric Tree Development Via the TSP1-like Domain. Matrix Biol. 2023 Jan 6; |
1 | J:138247 Saburi S, Hester I, Fischer E, Pontoglio M, Eremina V, Gessler M, Quaggin SE, Harrison R, Mount R, McNeill H, Loss of Fat4 disrupts PCP signaling and oriented cell division and leads to cystic kidney disease. Nat Genet. 2008 Aug;40(8):1010-5 |
1* | J:155223 Suomalainen M, Thesleff I, Patterns of Wnt pathway activity in the mouse incisor indicate absence of Wnt/beta-catenin signaling in the epithelial stem cells. Dev Dyn. 2009 Oct 5;239(1):364-372 |
1* | J:77089 Weidenfeld J, Shu W, Zhang L, Millar SE, Morrisey EE, The WNT7b promoter is regulated by TTF-1, GATA6, and Foxa2 in lung epithelium. J Biol Chem. 2002 Jun 7;277(23):21061-70 |
1* | J:105879 Zhang TJ, Hoffman BG, Ruiz de Algara T, Helgason CD, SAGE reveals expression of Wnt signalling pathway members during mouse prostate development. Gene Expr Patterns. 2006 Mar;6(3):310-24 |
Wnt16 wingless-type MMTV integration site family, member 16 (Synonyms: E130309I19Rik) | |
Results | Reference |
1* | J:152099 Bi Y, Huang J, He Y, Zhu GH, Su Y, He BC, Luo J, Wang Y, Kang Q, Luo Q, Chen L, Zuo GW, Jiang W, Liu B, Shi Q, Tang M, Zhang BQ, Weng Y, Huang A, Zhou L, Feng T, Luu HH, Haydon RC, He TC, Tang N, Wnt antagonist SFRP3 inhibits the differentiation of mouse hepatic progenitor cells. J Cell Biochem. 2009 Jun 26;108(1):295-303 |
1 | J:321068 Maimets M, Pedersen MT, Guiu J, Dreier J, Thodberg M, Antoku Y, Schweiger PJ, Rib L, Bressan RB, Miao Y, Garcia KC, Sandelin A, Serup P, Jensen KB, Mesenchymal-epithelial crosstalk shapes intestinal regionalisation via Wnt and Shh signalling. Nat Commun. 2022 Feb 7;13(1):715 |
1 | J:297063 Najarro EH, Huang J, Jacobo A, Quiruz LA, Grillet N, Cheng AG, Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea. Development. 2020 Oct 5;147(19):dev191981 |
1* | J:132979 Potok MA, Cha KB, Hunt A, Brinkmeier ML, Leitges M, Kispert A, Camper SA, WNT signaling affects gene expression in the ventral diencephalon and pituitary gland growth. Dev Dyn. 2008 Apr;237(4):1006-20 |
Wsb2 WD repeat and SOCS box-containing 2 | |
Results | Reference |
1* | J:121557 Sarraj MA, McClive PJ, Szczepny A, Daggag H, Loveland KL, Sinclair AH, Expression of Wsb2 in the developing and adult mouse testis. Reproduction. 2007 Apr;133(4):753-761 |
Wscd1 WSC domain containing 1 (Synonyms: MGC:55022) | |
Results | Reference |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
Wt1 WT1 transcription factor (Synonyms: D630046I19Rik, Wilms tumor 1 homolog, Wt-1) | |
Results | Reference |
1 | J:315767 Ahn SY, Kim Y, Kim ST, Swat W, Miner JH, Scaffolding proteins DLG1 and CASK cooperate to maintain the nephron progenitor population during kidney development. J Am Soc Nephrol. 2013 Jun;24(7):1127-38 |
1* | J:320610 Auguste D, Maier M, Baldwin C, Aoudjit L, Robins R, Gupta IR, Takano T, Disease-causing mutations of RhoGDIalpha induce Rac1 hyperactivation in podocytes. Small GTPases. 2016 Apr 2;7(2):107-21 |
1* | J:208419 Basta JM, Robbins L, Kiefer SM, Dorsett D, Rauchman M, Sall1 balances self-renewal and differentiation of renal progenitor cells. Development. 2014 Mar;141(5):1047-58 |
1* | J:293793 Basta JM, Singh AP, Robbins L, Stout L, Pherson M, Rauchman M, The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation. Dev Biol. 2020 Aug 15;464(2):176-187 |
1 | J:248734 Bolt CC, Negi S, Guimaraes-Camboa N, Zhang H, Troy JM, Lu X, Kispert A, Evans SM, Stubbs L, Tbx18 Regulates the Differentiation of Periductal Smooth Muscle Stroma and the Maintenance of Epithelial Integrity in the Prostate. PLoS One. 2016;11(4):e0154413 |
2 | J:192176 Casanova JC, Travisano S, de la Pompa JL, Epithelial-to-mesenchymal transition in epicardium is independent of snail1. Genesis. 2013 Jan;51(1):32-40 |
1 | J:194489 Chen SR, Chen M, Wang XN, Zhang J, Wen Q, Ji SY, Zheng QS, Gao F, Liu YX, The wilms tumor gene, wt1, maintains testicular cord integrity by regulating the expression of col4a1 and col4a2. Biol Reprod. 2013;88(3):56 |
1 | J:301645 Cleal L, McHaffie SL, Lee M, Hastie N, Martinez-Estrada OM, Chau YY, Resolving the heterogeneity of diaphragmatic mesenchyme: a novel mouse model of congenital diaphragmatic hernia. Dis Model Mech. 2021 Jan 26;14(1) |
1 | J:352476 Cunanan J, Rajyam SS, Sharif B, Udwan K, Rana A, De Gregorio V, Ricardo S, Elia A, Brooks B, Weins A, Pollak M, John R, Barua M, Mice with a Pax2 missense variant display impaired glomerular repair. Am J Physiol Renal Physiol. 2024 May 1;326(5):F704-F726 |
1 | J:196018 Fan X, Li Q, Pisarek-Horowitz A, Rasouly HM, Wang X, Bonegio RG, Wang H, McLaughlin M, Mangos S, Kalluri R, Holzman LB, Drummond IA, Brown D, Salant DJ, Lu W, Inhibitory effects of Robo2 on nephrin: a crosstalk between positive and negative signals regulating podocyte structure. Cell Rep. 2012 Jul 26;2(1):52-61 |
1 | J:189818 Haege S, Einer C, Thiele S, Mueller W, Nietzsche S, Lupp A, Mackay F, Schulz S, Stumm R, CXC chemokine receptor 7 (CXCR7) regulates CXCR4 protein expression and capillary tuft development in mouse kidney. PLoS One. 2012;7(8):e42814 |
1 | J:128007 Hartman HA, Lai HL, Patterson LT, Cessation of renal morphogenesis in mice. Dev Biol. 2007 Oct 15;310(2):379-87 |
2 | J:194051 Heliot C, Desgrange A, Buisson I, Prunskaite-Hyyrylainen R, Shan J, Vainio S, Umbhauer M, Cereghini S, HNF1B controls proximal-intermediate nephron segment identity in vertebrates by regulating Notch signalling components and Irx1/2. Development. 2013 Feb;140(4):873-85 |
1* | J:34982 Karavanova I, Vainio S, Thesleff I, Transient and recurrent expression of the Egr-1 gene in epithelial and mesenchymal cells during tooth morphogenesis suggests involvement in tissue interactions and in determination of cell fate. Mech Dev. 1992 Nov;39(1-2):41-50 |
2 | J:290695 Kothandapani A, Lewis SR, Noel JL, Zacharski A, Krellwitz K, Baines A, Winske S, Vezina CM, Kaftanovskaya EM, Agoulnik AI, Merton EM, Cohn MJ, Jorgensen JS, GLI3 resides at the intersection of hedgehog and androgen action to promote male sex differentiation. PLoS Genet. 2020 Jun;16(6):e1008810 |
2 | J:321428 Kruber P, Angay O, Winkler A, Bosl MR, Kneitz S, Heinze KG, Gessler M, Loss or oncogenic mutation of DROSHA impairs kidney development and function, but is not sufficient for Wilms tumor formation. Int J Cancer. 2019 Mar 15;144(6):1391-1400 |
1* | J:297658 Kulibin AY, Malolina EA, Formation of the rete testis during mouse embryonic development. Dev Dyn. 2020 Aug 27; |
1* | J:302867 Laurin M, Dumouchel A, Fukui Y, Cote JF, The Rac-specific exchange factors Dock1 and Dock5 are dispensable for the establishment of the glomerular filtration barrier in vivo. Small GTPases. 2013 Oct-Dec;4(4):221-30 |
1 | J:264112 Liu H, Chen S, Yao X, Li Y, Chen CH, Liu J, Saifudeen Z, El-Dahr SS, Histone deacetylases 1 and 2 regulate the transcriptional programs of nephron progenitors and renal vesicles. Development. 2018 May 18;145(10):dev153619 |
1 | J:339241 Liu, K., Intercellular genetic tracing of cardiac endothelium in the developing heart. Dev Cell. 2023 Aug 21;58(16):1502-1512 |
1* | J:67157 McCright B, Gao X, Shen L, Lozier J, Lan Y, Maguire M, Herzlinger D, Weinmaster G, Jiang R, Gridley T, Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation. Development. 2001 Feb;128(4):491-502 |
1* | J:82515 Miles CG, Slight J, Spraggon L, O'Sullivan M, Patek C, Hastie ND, Mice lacking the 68-amino-acid, mammal-specific N-terminal extension of WT1 develop normally and are fertile. Mol Cell Biol. 2003 Apr;23(7):2608-13 |
1* | J:59925 Miner JH, Li C, Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane. Dev Biol. 2000 Jan 15;217(2):278-89 |
1 | J:186318 Mohri Y, Oyama K, Sone M, Akamatsu A, Nishimori K, LGR4 Is Required for the Cell Survival of the Peripheral Mesenchyme at the Embryonic Stages of Nephrogenesis. Biosci Biotechnol Biochem. 2012 May 23;76(5):888-91 |
1 | J:156690 Morimoto M, Liu Z, Cheng HT, Winters N, Bader D, Kopan R, Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate. J Cell Sci. 2010 Jan 15;123(Pt 2):213-24 |
1 | J:243217 Muller M, Persson AB, Krueger K, Kirschner KM, Scholz H, The Wilms tumor protein WT1 stimulates transcription of the gene encoding insulin-like growth factor binding protein 5 (IGFBP5). Gene. 2017 Jul 01;619:21-29 |
1 | J:120229 Narlis M, Grote D, Gaitan Y, Boualia SK, Bouchard M, Pax2 and pax8 regulate branching morphogenesis and nephron differentiation in the developing kidney. J Am Soc Nephrol. 2007 Apr;18(4):1121-9 |
1 | J:309384 Neirijnck Y, Reginensi A, Renkema KY, Massa F, Kozlov VM, Dhib H, Bongers EMHF, Feitz WF, van Eerde AM, Lefebvre V, Knoers NVAM, Tabatabaei M, Schulz H, McNeill H, Schaefer F, Wegner M, Sock E, Schedl A, Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT). Kidney Int. 2018 May;93(5):1142-1153 |
1 | J:171035 Norden J, Grieskamp T, Lausch E, van Wijk B, van den Hoff MJ, Englert C, Petry M, Mommersteeg MT, Christoffels VM, Niederreither K, Kispert A, Wt1 and retinoic acid signaling in the subcoelomic mesenchyme control the development of the pleuropericardial membranes and the sinus horns. Circ Res. 2010 Apr 16;106(7):1212-20 |
2 | J:264647 O'Brien LL, Guo Q, Bahrami-Samani E, Park JS, Hasso SM, Lee YJ, Fang A, Kim AD, Guo J, Hong TM, Peterson KA, Lozanoff S, Raviram R, Ren B, Fogelgren B, Smith AD, Valouev A, McMahon AP, Transcriptional regulatory control of mammalian nephron progenitors revealed by multi-factor cistromic analysis and genetic studies. PLoS Genet. 2018 Jan;14(1):e1007181 |
1* | J:108109 Oxburgh L, Chu GC, Michael SK, Robertson EJ, TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development. 2004 Sep;131(18):4593-605 |
1 | J:361603 Scavuzzo MA, Szlachcic WJ, Hill MC, Ziojla NM, Teaw J, Carlson JC, Tiessen J, Chmielowiec J, Martin JF, Borowiak M, Pancreatic organogenesis mapped through space and time. Exp Mol Med. 2025 Feb;57(1):204-220 |
1 | J:302572 Schnerwitzki D, Hayn C, Perner B, Englert C, Wt1 Positive dB4 Neurons in the Hindbrain Are Crucial for Respiration. Front Neurosci. 2020;14:529487 |
2 | J:287023 Schnerwitzki D, Perry S, Ivanova A, Caixeta FV, Cramer P, Gunther S, Weber K, Tafreshiha A, Becker L, Vargas Panesso IL, Klopstock T, Hrabe de Angelis M, Schmidt M, Kullander K, Englert C, Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord. Life Sci Alliance. 2018 Aug;1(4):e201800106 |
1* | J:160194 Shaw L, Johnson PA, Kimber SJ, Gene expression profiling of the developing mouse kidney and embryo. In Vitro Cell Dev Biol Anim. 2010 Feb;46(2):155-65 |
1* | J:341715 Sui Y, Kou S, Ge K, Cao J, Liu C, Zhang H, Expression analysis of plvap in mouse heart development, homeostasis and injury. Gene Expr Patterns. 2023 Sep 28;50:119343 |
1 | J:363523 Sun X, Malandraki-Miller S, Kennedy T, Bassat E, Klaourakis K, Zhao J, Gamen E, Vieira JM, Tzahor E, Riley PR, The extracellular matrix protein agrin is essential for epicardial epithelial-to-mesenchymal transition during heart development. Development. 2021 May 1;148(9) |
1* | J:212053 Takasawa K, Kashimada K, Pelosi E, Takagi M, Morio T, Asahara H, Schlessinger D, Mizutani S, Koopman P, FOXL2 transcriptionally represses Sf1 expression by antagonizing WT1 during ovarian development in mice. FASEB J. 2014 May;28(5):2020-8 |
1 | J:266086 Tsukiji N, Inoue O, Morimoto M, Tatsumi N, Nagatomo H, Ueta K, Shirai T, Sasaki T, Otake S, Tamura S, Tachibana T, Okabe M, Hirashima M, Ozaki Y, Suzuki-Inoue K, Platelets play an essential role in murine lung development through Clec-2/podoplanin interaction. Blood. 2018 Sep 13;132(11):1167-1179 |
1 | J:333737 Wilson CL, Hung CF, Burkel BM, Ponik SM, Gharib SA, Schnapp LM, Nephronectin is required to maintain right lung lobar separation during embryonic development. Am J Physiol Lung Cell Mol Physiol. 2023 Jan 31; |
1 | J:324178 Wu Y, Duan P, Wen Y, Zhang J, Wang X, Dong J, Zhao Q, Feng S, Lv C, Guo Y, Namekawa SH, Yuan S, UHRF1 establishes crosstalk between somatic and germ cells in male reproduction. Cell Death Dis. 2022 Apr 19;13(4):377 |
1* | J:332246 Xie F, Zhu X, Liu X, Chen H, Wang J, N6-methyladenosine (m6A) RNA methylation mediated by methyltransferase complex subunit WTAP regulates amelogenesis. J Biol Chem. 2022 Dec;298(12):102715 |
1 | J:363737 Xue Z, Xuan H, Lau K, Su Y, Wegener M, Li K, Turner L, Adams M, Shi X, Wen H, Expression of ENL YEATS domain tumor mutations in nephrogenic or stromal lineage impairs kidney development. Nat Commun. 2025 Mar 14;16(1):2531 |
Wtap WT1 associating protein (Synonyms: 2810408K05Rik, 9430038B09Rik) | |
Results | Reference |
1* | J:332246 Xie F, Zhu X, Liu X, Chen H, Wang J, N6-methyladenosine (m6A) RNA methylation mediated by methyltransferase complex subunit WTAP regulates amelogenesis. J Biol Chem. 2022 Dec;298(12):102715 |
Wtip WT1 interacting protein | |
Results | Reference |
1 | J:341688 Xie X, Sun L, Duan Y, Lv Z, Yao X, Wang C, Chen X, Tian S, Yan L, Shao Y, Luo H, Liu J, SRSF2 in Sertoli cells is essential for testicular development and spermatogenesis in mice. FASEB J. 2023 May;37(5):e22918 |
Wwox WW domain-containing oxidoreductase (Synonyms: 5330426P09Rik, 9030416C10Rik, WOX1) | |
Results | Reference |
1* | J:89992 Chen ST, Chuang JI, Wang JP, Tsai MS, Li H, Chang NS, Expression of WW domain-containing oxidoreductase WOX1 in the developing murine nervous system. Neuroscience. 2004;124(4):831-9 |
Wwp2 WW domain containing E3 ubiquitin protein ligase 2 (Synonyms: 1300010O06Rik, AIP2) | |
Results | Reference |
2 | J:205660 Nakamura Y, Yamamoto K, He X, Otsuki B, Kim Y, Murao H, Soeda T, Tsumaki N, Deng JM, Zhang Z, Behringer RR, Crombrugghe Bd, Postlethwait JH, Warman ML, Nakamura T, Akiyama H, Wwp2 is essential for palatogenesis mediated by the interaction between Sox9 and mediator subunit 25. Nat Commun. 2011;2:251 |
Wwtr1 WW domain containing transcription regulator 1 (Synonyms: 2310058J06Rik, 2610021I22Rik, TAZ, transcriptional coactivator with PDZ binding motif) | |
Results | Reference |
1 | J:301556 Cha B, Ho YC, Geng X, Mahamud MR, Chen L, Kim Y, Choi D, Kim TH, Randolph GJ, Cao X, Chen H, Srinivasan RS, YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling. Development. 2020 Dec 13;147(23):dev195453 |
1 | J:289355 Cho H, Kim J, Ahn JH, Hong YK, Makinen T, Lim DS, Koh GY, YAP and TAZ Negatively Regulate Prox1 During Developmental and Pathologic Lymphangiogenesis. Circ Res. 2019 Jan 18;124(2):225-242 |
2 | J:293199 Crespo-Enriquez I, Hodgson T, Zakaria S, Cadoni E, Shah M, Allen S, Al-Khishali A, Mao Y, Yiu A, Petzold J, Villagomez-Olea G, Pitsillides AA, Irvine KD, Francis-West P, Dchs1-Fat4 regulation of osteogenic differentiation in mouse. Development. 2019 Jul 29;146(14):dev176776 |
1 | J:192856 George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE, Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol. 2012 Dec;32(24):5116-28 |
1 | J:289493 Isago H, Mitani A, Mikami Y, Horie M, Urushiyama H, Hamamoto R, Terasaki Y, Nagase T, Epithelial Expression of YAP and TAZ Is Sequentially Required in Lung Development. Am J Respir Cell Mol Biol. 2020 Feb;62(2):256-266 |
1 | J:317151 Lavado A, Gangwar R, Pare J, Wan S, Fan Y, Cao X, YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development. Dev Biol. 2021 Dec;480:39-49 |
1 | J:217604 Lavado A, Ware M, Pare J, Cao X, The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Development. 2014 Nov;141(21):4182-93 |
1 | J:307236 Li Y, Yang S, Qin L, Yang S, TAZ is required for chondrogenesis and skeletal development. Cell Discov. 2021 Apr 20;7(1):26 |
2 | J:132020 Makita R, Uchijima Y, Nishiyama K, Amano T, Chen Q, Takeuchi T, Mitani A, Nagase T, Yatomi Y, Aburatani H, Nakagawa O, Small EV, Cobo-Stark P, Igarashi P, Murakami M, Tominaga J, Sato T, Asano T, Kurihara Y, Kurihara H, Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ. Am J Physiol Renal Physiol. 2008 Mar;294(3):F542-53 |
1 | J:164957 Mitani A, Nagase T, Fukuchi K, Aburatani H, Makita R, Kurihara H, Transcriptional coactivator with PDZ-binding motif is essential for normal alveolarization in mice. Am J Respir Crit Care Med. 2009 Aug 15;180(4):326-38 |
1* | J:306471 Niki Y, Kobayashi Y, Moriyama K, Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth. Gene Expr Patterns. 2021 Jun;40:119182 |
1 | J:89484 Park KS, Whitsett JA, Di Palma T, Hong JH, Yaffe MB, Zannini M, TAZ interacts with TTF-1 and regulates expression of surfactant protein-C. J Biol Chem. 2004 Apr 23;279(17):17384-90 |
3 | J:326480 Terry BK, Park R, Cho SH, Crino PB, Kim S, Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex. Hum Mol Genet. 2022 Jun 22;31(12):1979-1996 |
1* | J:325177 Thiemann RF, Varney S, Moskwa N, Lamar J, Larsen M, LaFlamme SE, Regulation of myoepithelial differentiation. PLoS One. 2022;17(5):e0268668 |
1* | J:299510 Wang JJ, Ge W, Zhai QY, Liu JC, Sun XW, Liu WX, Li L, Lei CZ, Dyce PW, De Felici M, Shen W, Single-cell transcriptome landscape of ovarian cells during primordial follicle assembly in mice. PLoS Biol. 2020 Dec;18(12):e3001025 |
Xbp1 X-box binding protein 1 (Synonyms: D11Ertd39e, TREB-5, TREB5, XBP-1) | |
Results | Reference |
2* | J:294896 Aryal YP, Lee ES, Kim TY, Sung S, Kim JY, An SY, Jung JK, Ha JH, Suh JY, Yamamoto H, Sohn WJ, Cho SW, Lee Y, An CH, Kim JY, Stage-specific expression patterns of ER stress-related molecules in mice molars: Implications for tooth development. Gene Expr Patterns. 2020 Sep;37:119130 |
2* | J:14524 Clauss IM, Gravallese EM, Darling JM, Shapiro F, Glimcher MJ, Glimcher LH, In situ hybridization studies suggest a role for the basic region-leucine zipper protein hXBP-1 in exocrine gland and skeletal development during mouse embryogenesis. Dev Dyn. 1993 Jun;197(2):146-56 |
2 | J:158314 Firtina Z, Danysh BP, Bai X, Gould DB, Kobayashi T, Duncan MK, Abnormal expression of collagen IV in lens activates unfolded protein response resulting in cataract. J Biol Chem. 2009 Dec 18;284(51):35872-84 |
2* | J:168632 Firtina Z, Duncan MK, Unfolded Protein Response (UPR) is activated during normal lens development. Gene Expr Patterns. 2011 Jan-Feb;11(1-2):135-43 |
1* | J:74179 Nikaido T, Yokoya S, Mori T, Hagino S, Iseki K, Zhang Y, Takeuchi M, Takaki H, Kikuchi S, Wanaka A, Expression of the novel transcription factor OASIS, which belongs to the CREB/ATF family, in mouse embryo with special reference to bone development. Histochem Cell Biol. 2001 Aug;116(2):141-8 |
2* | J:221086 Patra D, DeLassus E, Liang G, Sandell LJ, Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. PLoS One. 2014;9(8):e105674 |
1 | J:203031 Rainger J, Keighren M, Keene DR, Charbonneau NL, Rainger JK, Fisher M, Mella S, Huang JT, Rose L, van't Hof R, Sakai LY, Jackson IJ, FitzPatrick DR, A Trans-Acting protein effect causes severe eye malformation in the Mp mouse. PLoS Genet. 2013;9(12):e1003998 |
1 | J:206302 Saito A, Kanemoto S, Zhang Y, Asada R, Hino K, Imaizumi K, Chondrocyte proliferation regulated by secreted luminal domain of ER stress transducer BBF2H7/CREB3L2. Mol Cell. 2014 Jan 9;53(1):127-39 |
1 | J:342871 Xiang J, Pompetti AJ, Faranda AP, Wang Y, Novo SG, Li DW, Duncan MK, ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment. Cells. 2023 Nov 16;12(22) |
Xiap X-linked inhibitor of apoptosis (Synonyms: 1110015C02Rik, Aipa, Api3, Birc4, IAP3, ILP-1) | |
Results | Reference |
1 | J:106392 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL, Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Dev Biol. 2006 Mar 1;291(1):67-82 |
1 | J:196310 Ene AC, Park S, Edelmann W, Taketo T, Caspase 9 is constitutively activated in mouse oocytes and plays a key role in oocyte elimination during meiotic prophase progression. Dev Biol. 2013 May 1;377(1):213-23 |
3 | J:294981 Liu X, Castle V, Taketo T, Interplay between Caspase 9 and X-linked Inhibitor of Apoptosis Protein (XIAP) in the oocyte elimination during fetal mouse development. Cell Death Dis. 2019 Oct 17;10(11):790 |
Xist inactive X specific transcripts | |
Results | Reference |
1* | J:74092 Eriksson A, Nordqvist K, Protocol for using signal peptide differential display and representational difference analysis to isolate differentially expressed cDNAs from fetal mouse brain. Brain Res Brain Res Protoc. 2001 Feb;6(3):119-28 |
Xlr X-linked lymphocyte-regulated | |
Results | Reference |
1 | J:158526 Naillat F, Prunskaite-Hyyrylainen R, Pietila I, Sormunen R, Jokela T, Shan J, Vainio SJ, Wnt4/5a signalling coordinates cell adhesion and entry into meiosis during presumptive ovarian follicle development. Hum Mol Genet. 2010 Apr 15;19(8):1539-50 |
1* | J:138760 Reynard LN, Turner JM, Cocquet J, Mahadevaiah SK, Toure A, Hoog C, Burgoyne PS, Expression analysis of the mouse multi-copy X-linked gene Xlr-related, meiosis-regulated (Xmr), reveals that Xmr encodes a spermatid-expressed cytoplasmic protein, SLX/XMR. Biol Reprod. 2007 Aug;77(2):329-35 |
Xlr5c X-linked lymphocyte-regulated 5C (Synonyms: Xlr5) | |
Results | Reference |
1* | J:33576 Levin ML, Chatterjee A, Pragliola A, Worley KC, Wehnert M, Zhuchenko O, Smith RF, Lee CC, Herman GE, A comparative transcription map of the murine bare patches (Bpa) and striated (Str) critical regions and human Xq28. Genome Res. 1996 Jun;6(6):465-77 |
Xpc xeroderma pigmentosum, complementation group C | |
Results | Reference |
1 | J:278988 Tian C, Johnson KR, TBX1 is required for normal stria vascularis and semicircular canal development. Dev Biol. 2019 Sep 21; |
Xpo1 exportin 1 (Synonyms: Crm1) | |
Results | Reference |
1* | J:294838 Li X, Feng Y, Yan M, Tu X, Xie B, Ni F, Qu C, Chen JG, Inhibition of Autism-Related Crm1 Disrupts Mitosis and Induces Apoptosis of the Cortical Neural Progenitors. Cereb Cortex. 2020 Jun 1;30(7):3960-3976 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Xpr1 xenotropic and polytropic retrovirus receptor 1 (Synonyms: Rmc-1, Rmc1, suppressor of yeast G deletion, Syg1) | |
Results | Reference |
1* | J:257428 Merametdjian L, Beck-Cormier S, Bon N, Couasnay G, Sourice S, Guicheux J, Gaucher C, Beck L, Expression of Phosphate Transporters during Dental Mineralization. J Dent Res. 2018 Feb;97(2):209-217 |
Xylt1 xylosyltransferase 1 | |
Results | Reference |
2 | J:205339 Mis EK, Liem KF Jr, Kong Y, Schwartz NB, Domowicz M, Weatherbee SD, Forward genetics defines Xylt1 as a key, conserved regulator of early chondrocyte maturation and skeletal length. Dev Biol. 2014 Jan 1;385(1):67-82 |
Yap1 yes-associated protein 1 (Synonyms: Yap, Yki, yorkie) | |
Results | Reference |
1 | J:301556 Cha B, Ho YC, Geng X, Mahamud MR, Chen L, Kim Y, Choi D, Kim TH, Randolph GJ, Cao X, Chen H, Srinivasan RS, YAP and TAZ maintain PROX1 expression in the developing lymphatic and lymphovenous valves in response to VEGF-C signaling. Development. 2020 Dec 13;147(23):dev195453 |
1 | J:289355 Cho H, Kim J, Ahn JH, Hong YK, Makinen T, Lim DS, Koh GY, YAP and TAZ Negatively Regulate Prox1 During Developmental and Pathologic Lymphangiogenesis. Circ Res. 2019 Jan 18;124(2):225-242 |
1 | J:293199 Crespo-Enriquez I, Hodgson T, Zakaria S, Cadoni E, Shah M, Allen S, Al-Khishali A, Mao Y, Yiu A, Petzold J, Villagomez-Olea G, Pitsillides AA, Irvine KD, Francis-West P, Dchs1-Fat4 regulation of osteogenic differentiation in mouse. Development. 2019 Jul 29;146(14):dev176776 |
1 | J:358347 Dias AP, Rehmani T, Salih M, Tuana B, Tail-anchored membrane protein SLMAP3 is essential for targeting centrosomal proteins to the nuclear envelope in skeletal myogenesis. Open Biol. 2024 Oct;14(10):240094 |
1 | J:307319 George NM, Boerner BP, Mir SU, Guinn Z, Sarvetnick NE, Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass. Mol Endocrinol. 2015 Nov;29(11):1594-607 |
1 | J:192856 George NM, Day CE, Boerner BP, Johnson RL, Sarvetnick NE, Hippo signaling regulates pancreas development through inactivation of Yap. Mol Cell Biol. 2012 Dec;32(24):5116-28 |
1 | J:353335 Grego-Bessa J, Gomez-Apinaniz P, Prados B, Gomez MJ, MacGrogan D, de la Pompa JL, Nrg1 Regulates Cardiomyocyte Migration and Cell Cycle in Ventricular Development. Circ Res. 2023 Nov 10;133(11):927-943 |
1* | J:283394 Hughes LJ, Park R, Lee MJ, Terry BK, Lee DJ, Kim H, Cho SH, Kim S, Yap/Taz are required for establishing the cerebellar radial glia scaffold and proper foliation. Dev Biol. 2020 Jan 1;457(1):150-162 |
1 | J:289493 Isago H, Mitani A, Mikami Y, Horie M, Urushiyama H, Hamamoto R, Terasaki Y, Nagase T, Epithelial Expression of YAP and TAZ Is Sequentially Required in Lung Development. Am J Respir Cell Mol Biol. 2020 Feb;62(2):256-266 |
1 | J:304850 Jiang C, Javed A, Kaiser L, Nava MM, Xu R, Brandt DT, Zhao D, Mayer B, Fernandez-Baldovinos J, Zhou L, Hoss C, Sawmynaden K, Oleksy A, Matthews D, Weinstein LS, Hahn H, Grone HJ, Graumann PL, Niessen CM, Offermanns S, Wickstrom SA, Worzfeld T, Mechanochemical control of epidermal stem cell divisions by B-plexins. Nat Commun. 2021 Feb 26;12(1):1308 |
1* | J:237224 Kim JY, Park R, Lee JH, Shin J, Nickas J, Kim S, Cho SH, Yap is essential for retinal progenitor cell cycle progression and RPE cell fate acquisition in the developing mouse eye. Dev Biol. 2016 Nov 15;419(2):336-347 |
1* | J:309394 Kwon HJ, Li L, Jung HS, Hippo pathway/Yap regulates primary enamel knot and dental cusp patterning in tooth morphogenesis. Cell Tissue Res. 2015 Nov;362(2):447-51 |
1 | J:317151 Lavado A, Gangwar R, Pare J, Wan S, Fan Y, Cao X, YAP/TAZ maintain the proliferative capacity and structural organization of radial glial cells during brain development. Dev Biol. 2021 Dec;480:39-49 |
1 | J:217604 Lavado A, Ware M, Pare J, Cao X, The tumor suppressor Nf2 regulates corpus callosum development by inhibiting the transcriptional coactivator Yap. Development. 2014 Nov;141(21):4182-93 |
1 | J:240786 Lee DH, Park JO, Kim TS, Kim SK, Kim TH, Kim MC, Park GS, Kim JH, Kuninaka S, Olson EN, Saya H, Kim SY, Lee H, Lim DS, LATS-YAP/TAZ controls lineage specification by regulating TGFbeta signaling and Hnf4alpha expression during liver development. Nat Commun. 2016 Jun 30;7:11961 |
1* | J:170274 Li L, Kwon HJ, Harada H, Ohshima H, Cho SW, Jung HS, Expression patterns of ABCG2, Bmi-1, Oct-3/4, and Yap in the developing mouse incisor. Gene Expr Patterns. 2011 Mar-Apr;11(3-4):163-70 |
1* | J:224948 Lin C, Yao E, Chuang PT, A conserved MST1/2-YAP axis mediates Hippo signaling during lung growth. Dev Biol. 2015 Jul 1;403(1):101-13 |
1 | J:239657 Mao Y, Francis-West P, Irvine KD, Fat4/Dchs1 signaling between stromal and cap mesenchyme cells influences nephrogenesis and ureteric bud branching. Development. 2015 Aug 01;142(15):2574-85 |
1* | J:306379 Mohad V, Lungova V, Verheyden J, Thibeault SL, Inactivation of Lats1 and Lats2 highlights the role of hippo pathway effector YAP in larynx and vocal fold epithelium morphogenesis. Dev Biol. 2021 May;473:33-49 |
1 | J:320686 Molina LM, Zhu J, Li Q, Pradhan-Sundd T, Krutsenko Y, Sayed K, Jenkins N, Vats R, Bhushan B, Ko S, Hu S, Poddar M, Singh S, Tao J, Sundd P, Singhi A, Watkins S, Ma X, Benos PV, Feranchak A, Michalopoulos G, Nejak-Bowen K, Watson A, Bell A, Monga SP, Compensatory hepatic adaptation accompanies permanent absence of intrahepatic biliary network due to YAP1 loss in liver progenitors. Cell Rep. 2021 Jul 6;36(1):109310 |
1* | J:306471 Niki Y, Kobayashi Y, Moriyama K, Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth. Gene Expr Patterns. 2021 Jun;40:119182 |
1 | J:346063 Rehmani T, Dias AP, Kamal M, Salih M, Tuana BS, Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway. Int J Mol Sci. 2024 Mar 1;25(5) |
1 | J:266255 Scavuzzo MA, Hill MC, Chmielowiec J, Yang D, Teaw J, Sheng K, Kong Y, Bettini M, Zong C, Martin JF, Borowiak M, Endocrine lineage biases arise in temporally distinct endocrine progenitors during pancreatic morphogenesis. Nat Commun. 2018 Aug 22;9(1):3356 |
1 | J:206876 Song JY, Park R, Kim JY, Hughes L, Lu L, Kim S, Johnson RL, Cho SH, Dual function of Yap in the regulation of lens progenitor cells and cellular polarity. Dev Biol. 2014 Feb 15;386(2):281-90 |
3 | J:326480 Terry BK, Park R, Cho SH, Crino PB, Kim S, Abnormal activation of Yap/Taz contributes to the pathogenesis of tuberous sclerosis complex. Hum Mol Genet. 2022 Jun 22;31(12):1979-1996 |
1 | J:362739 Wu Y, Qin K, Xu Y, Rajhans S, Vo T, Lopez KM, Liu J, Nipper MH, Deng J, Yin X, Ramjit LR, Ye Z, Luan Y, Arda HE, Wang P, Hippo pathway-mediated YAP1/TAZ inhibition is essential for proper pancreatic endocrine specification and differentiation. Elife. 2024 Jul 25;13 |
1 | J:342339 Xia M, Wu M, Li Y, Liu Y, Jia G, Lou Y, Ma J, Gao Q, Xie M, Chen Y, He Y, Li H, Li W, Varying mechanical forces drive sensory epithelium formation. Sci Adv. 2023 Nov 3;9(44):eadf2664 |
1 | J:169106 Zhang H, Pasolli HA, Fuchs E, Yes-associated protein (YAP) transcriptional coactivator functions in balancing growth and differentiation in skin. Proc Natl Acad Sci U S A. 2011 Feb 8;108(6):2270-5 |
1 | J:358835 Zhang J, Gao J, Zeng X, Wang Z, Chen C, Rong C, Li S, Cai L, Wang L, Zhang L, Tian Z, A novel Cdc42-YAP-fibronectin signaling axis regulates ameloblast differentiation during early enamel formation. Biochim Biophys Acta Mol Basis Dis. 2024 Nov 14;1871(2):167570 |
1 | J:261328 Zou J, Ma W, Li J, Littlejohn R, Zhou H, Kim IM, Fulton DJR, Chen W, Weintraub NL, Zhou J, Su H, Neddylation mediates ventricular chamber maturation through repression of Hippo signaling. Proc Natl Acad Sci U S A. 2018 Apr 24;115(17):E4101-E4110 |
Ybx3 Y box protein 3 (Synonyms: Csda, dbpA, Dpba, MSY3, MSY4, oxyR, Yb2) | |
Results | Reference |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Yeats4 YEATS domain containing 4 (Synonyms: 4930573H17Rik, B230215M10Rik, GAS41, NuBI-1) | |
Results | Reference |
1* | J:303715 Woodruff ED, Gutierrez GC, Van Otterloo E, Williams T, Cohn MJ, Anomalous incisor morphology indicates tissue-specific roles for Tfap2a and Tfap2b in tooth development. Dev Biol. 2021 Apr;472:67-74 |
1* | J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903 |
Yes1 YES proto-oncogene 1, Src family tyrosine kinase (Synonyms: Yes) | |
Results | Reference |
1 | J:101055 Kuo G, Arnaud L, Kronstad-O'Brien P, Cooper JA, Absence of Fyn and Src causes a reeler-like phenotype. J Neurosci. 2005 Sep 14;25(37):8578-86 |
1* | J:55945 Wang JP, Chuang SM, Shen CL, Chen ST, Expression of Src family during development of the mouse nervous system. Biomed Res. 1998 OCT;19(5):315-325 |
Yme1l1 YME1-like 1 (S. cerevisiae) (Synonyms: ATP-dependent metalloprotease FtsH1, Ftsh) | |
Results | Reference |
1 | J:62529 Coppola M, Pizzigoni A, Banfi S, Bassi MT, Casari G, Incerti B, Identification and characterization of YME1L1, a novel paraplegin-related gene. Genomics. 2000 May 15;66(1):48-54 |
Ypel2 yippee like 2 (Synonyms: E130113K08Rik) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Ypel4 yippee like 4 | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Ythdc2 YTH domain containing 2 (Synonyms: 3010002F02Rik) | |
Results | Reference |
1* | J:253477 Bailey AS, Batista PJ, Gold RS, Chen YG, de Rooij DG, Chang HY, Fuller MT, The conserved RNA helicase YTHDC2 regulates the transition from proliferation to differentiation in the germline. Elife. 2017 Oct 31;6:e26116 |
Ythdf1 YTH N6-methyladenosine RNA binding protein 1 (Synonyms: 2210410K23Rik) | |
Results | Reference |
1 | J:328038 Niu F, Che P, Yang Z, Zhang J, Yang L, Zhuang M, Ou X, Ji SJ, m(6)A regulation of cortical and retinal neurogenesis is mediated by the redundant m(6)A readers YTHDFs. iScience. 2022 Sep 16;25(9):104908 |
Ywhae tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide (Synonyms: 14-3-3 epsilon) | |
Results | Reference |
2 | J:192860 Kosaka Y, Cieslik KA, Li L, Lezin G, Maguire CT, Saijoh Y, Toyo-oka K, Gambello MJ, Vatta M, Wynshaw-Boris A, Baldini A, Yost HJ, Brunelli L, 14-3-3epsilon plays a role in cardiac ventricular compaction by regulating the cardiomyocyte cell cycle. Mol Cell Biol. 2012 Dec;32(24):5089-102 |
1* | J:84075 Toyo-oka K, Shionoya A, Gambello MJ, Cardoso C, Leventer R, Ward HL, Ayala R, Tsai LH, Dobyns W, Ledbetter D, Hirotsune S, Wynshaw-Boris A, 14-3-3epsilon is important for neuronal migration by binding to NUDEL: a molecular explanation for Miller-Dieker syndrome. Nat Genet. 2003 Jul;34(3):274-85 |
Ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide (Synonyms: 1110013I11Rik, 14-3-3 zeta) | |
Results | Reference |
1* | J:67747 Thut CJ, Rountree RB, Hwa M, Kingsley DM, A large-scale in situ screen provides molecular evidence for the induction of eye anterior segment structures by the developing lens. Dev Biol. 2001 Mar 1;231(1):63-76 |
Yy1 YY1 transcription factor (Synonyms: delta transcription factor, NF-E1, UCRBP transcription factor, Yin Yang 1) | |
Results | Reference |
1 | J:221142 Beketaev I, Zhang Y, Kim EY, Yu W, Qian L, Wang J, Critical role of YY1 in cardiac morphogenesis. Dev Dyn. 2015 May;244(5):669-80 |
1 | J:240472 Kumar N, Srivillibhuthur M, Joshi S, Walton KD, Zhou A, Faller WJ, Perekatt AO, Sansom OJ, Gumucio DL, Xing J, Bonder EM, Gao N, White E, Verzi MP, A YY1-dependent increase in aerobic metabolism is indispensable for intestinal organogenesis. Development. 2016 Oct 15;143(20):3711-3722 |
Zap70 zeta-chain (TCR) associated protein kinase (Synonyms: Srk, TZK, ZAP-70) | |
Results | Reference |
1* | J:317552 Casey SC, Blumberg B, The steroid and xenobiotic receptor negatively regulates B-1 cell development in the fetal liver. Mol Endocrinol. 2012 Jun;26(6):916-25 |
Zbed3 zinc finger, BED type containing 3 (Synonyms: 0610037K01Rik, 2610005H11Rik) | |
Results | Reference |
2* | J:310127 Ruan X, Liu G, Zhou J, Chen P, Sun C, Liu W, Wu C, Hou L, Yin B, Qiang B, Shu P, Peng X, Zbed3 Is Indispensable for Wnt Signaling Regulation of Cortical Layers Formation in Developing Brain. Cereb Cortex. 2021 Jul 29;31(9):4078-4091 |
Zbtb7b zinc finger and BTB domain containing 7B (Synonyms: c-Krox, Thpok, Th-POK, Zfp67) | |
Results | Reference |
1* | J:35138 Galera P, Park RW, Ducy P, Mattei MG, Karsenty G, c-Krox binds to several sites in the promoter of both mouse type I collagen genes. Structure/function study and developmental expression analysis. J Biol Chem. 1996 Aug 30;271(35):21331-9 |
Zbtb7c zinc finger and BTB domain containing 7C (Synonyms: B230208J24Rik, Kr-pok, Zbtb36) | |
Results | Reference |
1 | J:152858 Garcia-Ortiz JE, Pelosi E, Omari S, Nedorezov T, Piao Y, Karmazin J, Uda M, Cao A, Cole SW, Forabosco A, Schlessinger D, Ottolenghi C, Foxl2 functions in sex determination and histogenesis throughout mouse ovary development. BMC Dev Biol. 2009;9:36 |
1 | J:356085 Wang J, Tian GG, Zheng Z, Li B, Xing Q, Wu J, Comprehensive Transcriptomic Analysis of Mouse Gonadal Development Involving Sexual Differentiation, Meiosis and Gametogenesis. Biol Proced Online. 2019;21:20 |
Zbtb16 zinc finger and BTB domain containing 16 (Synonyms: Green's luxoid, PLZF, Zfp145) | |
Results | Reference |
1* | J:26895 Avantaggiato V, Pandolfi PP, Ruthardt M, Hawe N, Acampora D, Pelicci PG, Simeone A, Developmental analysis of murine Promyelocyte Leukemia Zinc Finger (PLZF) gene expression: implications for the neuromeric model of the forebrain organization. J Neurosci. 1995 Jul;15(7 Pt 1):4927-42 |
1* | J:23958 Cook M, Gould A, Brand N, Davies J, Strutt P, Shaknovich R, Licht J, Waxman S, Chen Z, Gluecksohn-Waelsch S, Krumlauf R, Zelent A, Expression of the zinc-finger gene PLZF at rhombomere boundaries in the vertebrate hindbrain. Proc Natl Acad Sci U S A. 1995 Mar 14;92(6):2249-53 |
1 | J:276979 Lin HC, Ching YH, Huang CC, Pao PC, Lee YH, Chang WC, Kao TJ, Lee YC, Promyelocytic leukemia zinc finger is involved in the formation of deep layer cortical neurons. J Biomed Sci. 2019 Apr 26;26(1):30 |
1 | J:168860 Payne CJ, Gallagher SJ, Foreman O, Dannenberg JH, Depinho RA, Braun RE, Sin3a is required by sertoli cells to establish a niche for undifferentiated spermatogonia, germ cell tumors, and spermatid elongation. Stem Cells. 2010 Aug;28(8):1424-34 |
1* | J:241573 Pui HP, Saga Y, Gonocytes-to-spermatogonia transition initiates prior to birth in murine testes and it requires FGF signaling. Mech Dev. 2017 Apr;144(Pt B):125-139 |
1* | J:258304 Pui HP, Saga Y, NANOS2 acts as an intrinsic regulator of gonocytes-to-spermatogonia transition in the murine testes. Mech Dev. 2018 Feb;149:27-40 |
1 | J:357469 Sivori M, Dempsey B, Chettouh Z, Boismoreau F, Ayerdi M, et al., The pelvic organs receive no parasympathetic innervation. Elife. 2024;15 |
Zbtb17 zinc finger and BTB domain containing 17 (Synonyms: Miz1, mZ13, Zfp100) | |
Results | Reference |
1 | J:29058 Schulz TC, Hopwood B, Rathjen PD, Wells JR, An unusual arrangement of 13 zinc fingers in the vertebrate gene Z13. Biochem J. 1995 Oct 1;311(Pt 1):219-24 |
Zbtb18 zinc finger and BTB domain containing 18 (Synonyms: RP58, Zfp238) | |
Results | Reference |
1 | J:184000 Baubet V, Xiang C, Molczan A, Roccograndi L, Melamed S, Dahmane N, Rp58 is essential for the growth and patterning of the cerebellum and for glutamatergic and GABAergic neuron development. Development. 2012 Jun;139(11):1903-9 |
3 | J:269861 Cargnin F, Kwon JS, Katzman S, Chen B, Lee JW, Lee SK, FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018 Dec 5;100(5):1083-1096.e5 |
2* | J:136997 Ohtaka-Maruyama C, Miwa A, Kawano H, Kasai M, Okado H, Spatial and temporal expression of RP58, a novel zinc finger transcriptional repressor, in mouse brain. J Comp Neurol. 2007 Jun 20;502(6):1098-108 |
1 | J:150768 Okado H, Ohtaka-Maruyama C, Sugitani Y, Fukuda Y, Ishida R, Hirai S, Miwa A, Takahashi A, Aoki K, Mochida K, Suzuki O, Honda T, Nakajima K, Ogawa M, Terashima T, Matsuda J, Kawano H, Kasai M, The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Dev Biol. 2009 Jul 15;331(2):140-51 |
1 | J:184434 Xiang C, Baubet V, Pal S, Holderbaum L, Tatard V, Jiang P, Davuluri RV, Dahmane N, RP58/ZNF238 directly modulates proneurogenic gene levels and is required for neuronal differentiation and brain expansion. Cell Death Differ. 2012 Apr;19(4):692-702 |
1* | J:310487 Xiang C, Frietze KK, Bi Y, Li Y, Dal Pozzo V, Pal S, Alexander N, Baubet V, D'Acunto V, Mason CE, Davuluri RV, Dahmane N, RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons. Mol Cell Biol. 2021 Jun 23;41(7):e0052620 |
Zbtb20 zinc finger and BTB domain containing 20 (Synonyms: 1300017A20Rik, 7330412A13Rik, A930017C21Rik, D16Wsu73e, HOF, Zfp288) | |
Results | Reference |
1 | J:236889 Cao D, Ma X, Cai J, Luan J, Liu AJ, Yang R, Cao Y, Zhu X, Zhang H, Chen YX, Shi Y, Shi GX, Zou D, Cao X, Grusby MJ, Xie Z, Zhang WJ, ZBTB20 is required for anterior pituitary development and lactotrope specification. Nat Commun. 2016 Apr 15;7:11121 |
1 | J:265822 Chapman H, Riesenberg A, Ehrman LA, Kohli V, Nardini D, Nakafuku M, Campbell K, Waclaw RR, Gsx transcription factors control neuronal versus glial specification in ventricular zone progenitors of the mouse lateral ganglionic eminence. Dev Biol. 2018 Oct 1;442(1):115-126 |
1* | J:66794 Mitchelmore C, Kjaerulff KM, Pedersen HC, Nielsen JV, Rasmussen TE, Fisker MF, Finsen B, Pedersen KM, Jensen NA, Characterization of two novel nuclear BTB/POZ domain zinc finger isoforms. Association with differentiation of hippocampal neurons, cerebellar granule cells, and macroglia. J Biol Chem. 2002 Mar 1;277(9):7598-609 |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
1* | J:363178 Ren AJ, Wei C, Liu YJ, Liu M, Wang P, Fan J, Wang K, Zhang S, Qin Z, Ren QX, Zheng Y, Chen YX, Xie Z, Gao L, Zhu Y, Zhang Y, Yang HT, Zhang WJ, ZBTB20 Regulates SERCA2a Activity and Myocardial Contractility Through Phospholamban. Circ Res. 2024 Feb 2;134(3):252-265 |
1 | J:220958 Rosenthal EH, Tonchev AB, Stoykova A, Chowdhury K, Regulation of archicortical arealization by the transcription factor Zbtb20. Hippocampus. 2012 Nov;22(11):2144-56 |
3 | J:109567 Shen WB, Plachez C, Mongi AS, Richards LJ, Identification of candidate genes at the corticoseptal boundary during development. Gene Expr Patterns. 2006 Jun;6(5):471-81 |
2 | J:279607 Tonchev AB, Tuoc TC, Rosenthal EH, Studer M, Stoykova A, Zbtb20 modulates the sequential generation of neuronal layers in developing cortex. Mol Brain. 2016 Jun 9;9(1):65 |
1* | J:316179 Wang A, Wang J, Tian K, Huo D, Ye H, Li S, Zhao C, Zhang B, Zheng Y, Xu L, Hua X, Wang K, Wu QF, Wu X, Zeng T, Liu Y, Zhou Y, An epigenetic circuit controls neurogenic programs during neocortex development. Development. 2021;148:dev199772 |
1 | J:159315 Xie Z, Ma X, Ji W, Zhou G, Lu Y, Xiang Z, Wang YX, Zhang L, Hu Y, Ding YQ, Zhang WJ, Zbtb20 is essential for the specification of CA1 field identity in the developing hippocampus. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6510-5 |
1 | J:343328 Xie Z, Ma XH, Bai QF, Tang J, Sun JH, Jiang F, Guo W, Wang CM, Yang R, Wen YC, Wang FY, Chen YX, Zhang H, He DZ, Kelley MW, Yang S, Zhang WJ, ZBTB20 is essential for cochlear maturation and hearing in mice. Proc Natl Acad Sci U S A. 2023 Jun 13;120(24):e2220867120 |
Zbtb26 zinc finger and BTB domain containing 26 (Synonyms: A630026F21Rik) | |
Results | Reference |
1* | J:333712 Liang J, Liang J, Tan Q, Wang Z, ELAC2 Functions as a Key Gene in the Early Development of Placental Formation Based on WGCNA. Cells. 2023 Feb 14;12(4) |
Zc4h2 zinc finger, C4H2 domain containing (Synonyms: LOC245522, mKIAA1166) | |
Results | Reference |
1* | J:286599 Song NN, Ma P, Zhang Q, Zhang L, Wang H, Zhang L, Zhu L, He CH, Mao B, Ding YQ, Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 2020 Mar 30;147(6):dev185199 |
Zcchc12 zinc finger, CCHC domain containing 12 (Synonyms: 2810028A01Rik, Sizn1) | |
Results | Reference |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
Zcwpw1 zinc finger, CW type with PWWP domain 1 (Synonyms: LOC381678) | |
Results | Reference |
1* | J:278517 Li M, Huang T, Li MJ, Zhang CX, Yu XC, Yin YY, Liu C, Wang X, Feng HW, Zhang T, Liu MF, Han CS, Lu G, Li W, Ma JL, Chen ZJ, Liu HB, Liu K, The histone modification reader ZCWPW1 is required for meiosis prophase I in male but not in female mice. Sci Adv. 2019;5(8):eaax1101 |
Zdbf2 zinc finger, DBF-type containing 2 (Synonyms: 4930431J08Rik, 9330107J05Rik) | |
Results | Reference |
1* | J:207604 Duffie R, Ajjan S, Greenberg MV, Zamudio N, Escamilla del Arenal M, Iranzo J, Okamoto I, Barbaux S, Fauque P, Bourc'his D, The Gpr1/Zdbf2 locus provides new paradigms for transient and dynamic genomic imprinting in mammals. Genes Dev. 2014 Mar 1;28(5):463-78 |
Zdbf2linc Zdbf2 associated long non-coding RNA | |
Results | Reference |
1* | J:316637 Strogantsev R, Krueger F, Yamazawa K, Shi H, Gould P, Goldman-Roberts M, McEwen K, Sun B, Pedersen R, Ferguson-Smith AC, Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression. Genome Biol. 2015 May 30;16:112 |
Zdhhc21 zinc finger, DHHC domain containing 21 (Synonyms: 9130404H11Rik, D130004H04Rik, dep) | |
Results | Reference |
1 | J:161749 Mill P, Lee AW, Fukata Y, Tsutsumi R, Fukata M, Keighren M, Porter RM, McKie L, Smyth I, Jackson IJ, Palmitoylation regulates epidermal homeostasis and hair follicle differentiation. PLoS Genet. 2009 Nov;5(11):e1000748 |
Zeb1 zinc finger E-box binding homeobox 1 (Synonyms: 3110032K11Rik, AREB6, [delta]EF1, MEB1, Nil2, Tcf18, Tcf8, Tw, ZEB, Zfhep, Zfhx1a, Zfx1a) | |
Results | Reference |
2 | J:155396 Bellon E, Luyten FP, Tylzanowski P, delta-EF1 is a negative regulator of Ihh in the developing growth plate. J Cell Biol. 2009 Nov 30;187(5):685-99 |
1* | J:310454 Gu Y, Zhao Y, Zhou Y, Xie Y, Ju P, Long Y, Liu J, Ni D, Cao F, Lyu Z, Mao Z, Hao J, Li Y, Wan Q, Kanyomse Q, Liu Y, Ren D, Ning Y, Li X, Zhou Q, Li B, Zeb1 Is a Potential Regulator of Six2 in the Proliferation, Apoptosis and Migration of Metanephric Mesenchyme Cells. Int J Mol Sci. 2016 Aug 6;17(8):1283 |
1 | J:236173 Guo W, Benlhabib H, Mendelson CR, The MicroRNA 29 Family Promotes Type II Cell Differentiation in Developing Lung. Mol Cell Biol. 2016 Aug 15;36(16):2141 |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:131173 Liu Y, El-Naggar S, Darling DS, Higashi Y, Dean DC, Zeb1 links epithelial-mesenchymal transition and cellular senescence. Development. 2008 Feb;135(3):579-88 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:242339 Ohayon D, Garces A, Joly W, Soukkarieh C, Takagi T, Sabourin JC, Agius E, Darling DS, De Santa Barbara P, Higashi Y, Stolt CC, Hugnot JP, Richardson WD, Carroll P, Pattyn A, Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Cell Rep. 2016 Nov 01;17(6):1473-1481 |
1 | J:354217 Ohyama K, Shinohara HM, Takayama N, Ogawa R, Omura S, Hayashida M, Takahashi T, Differentiation stage-specific expression of transcriptional regulators for epithelial mesenchymal transition in dentate granule progenitors. Front Neurosci. 2024;18:1425849 |
1* | J:274453 Shin JO, Kim EJ, Cho KW, Nakagawa E, Kwon HJ, Cho SW, Jung HS, BMP4 signaling mediates Zeb family in developing mouse tooth. Histochem Cell Biol. 2012 Jun;137(6):791-800 |
1* | J:306094 Xiao Y, Lin YX, Cui Y, Zhang Q, Pei F, Zuo HY, Liu H, Chen Z, Zeb1 Promotes Odontoblast Differentiation in a Stage-Dependent Manner. J Dent Res. 2021 Jun;100(6):648-657 |
Zeb2 zinc finger E-box binding homeobox 2 (Synonyms: 9130203F04Rik, D130016B08Rik, mKIAA0569, SIP1, Zfhx1b, Zfx1b) | |
Results | Reference |
1* | J:88775 Bassez G, Camand OJ, Cacheux V, Kobetz A, Dastot-Le Moal F, Marchant D, Catala M, Abitbol M, Goossens M, Pleiotropic and diverse expression of ZFHX1B gene transcripts during mouse and human development supports the various clinical manifestations of the 'Mowat-Wilson' syndrome. Neurobiol Dis. 2004 Mar;15(2):240-50 |
1 | J:299148 Deryckere A, Stappers E, Dries R, Peyre E, van den Berghe V, Conidi A, Zampeta FI, Francis A, Bresseleers M, Stryjewska A, Vanlaer R, Maas E, Smal IV, van IJcken WFJ, Grosveld FG, Nguyen L, Huylebroeck D, Seuntjens E, Multifaceted actions of Zeb2 in postnatal neurogenesis from the ventricular-subventricular zone to the olfactory bulb. Development. 2020 May 26;147(10):dev184861 |
1 | J:312814 Fernandez Vallone V, Leprovots M, Ribatallada-Soriano D, Gerbier R, Lefort A, Libert F, Vassart G, Garcia MI, LGR5 controls extracellular matrix production by stem cells in the developing intestine. EMBO Rep. 2020 Jul 3;21(7):e49224 |
1 | J:236173 Guo W, Benlhabib H, Mendelson CR, The MicroRNA 29 Family Promotes Type II Cell Differentiation in Developing Lung. Mol Cell Biol. 2016 Aug 15;36(16):2141 |
1 | J:207861 Manthey AL, Lachke SA, FitzGerald PG, Mason RW, Scheiblin DA, McDonald JH, Duncan MK, Loss of Sip1 leads to migration defects and retention of ectodermal markers during lens development. Mech Dev. 2014 Feb;131:86-110 |
1 | J:123406 Miquelajauregui A, Van de Putte T, Polyakov A, Nityanandam A, Boppana S, Seuntjens E, Karabinos A, Higashi Y, Huylebroeck D, Tarabykin V, Smad-interacting protein-1 (Zfhx1b) acts upstream of Wnt signaling in the mouse hippocampus and controls its formation. Proc Natl Acad Sci U S A. 2007 Jul 31;104(31):12919-24 |
2 | J:207850 Nishizaki Y, Takagi T, Matsui F, Higashi Y, SIP1 expression patterns in brain investigated by generating a SIP1-EGFP reporter knock-in mouse. Genesis. 2014 Jan;52(1):56-67 |
1 | J:242339 Ohayon D, Garces A, Joly W, Soukkarieh C, Takagi T, Sabourin JC, Agius E, Darling DS, De Santa Barbara P, Higashi Y, Stolt CC, Hugnot JP, Richardson WD, Carroll P, Pattyn A, Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor. Cell Rep. 2016 Nov 01;17(6):1473-1481 |
1 | J:255143 Rasouly HM, Kumar S, Chan S, Pisarek-Horowitz A, Sharma R, Xi QJ, Nishizaki Y, Higashi Y, Salant DJ, Maas RL, Lu W, Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease. Kidney Int. 2016 Dec;90(6):1262-1273 |
1* | J:274453 Shin JO, Kim EJ, Cho KW, Nakagawa E, Kwon HJ, Cho SW, Jung HS, BMP4 signaling mediates Zeb family in developing mouse tooth. Histochem Cell Biol. 2012 Jun;137(6):791-800 |
1 | J:286533 Tenney AP, Livet J, Belton T, Prochazkova M, Pearson EM, Whitman MC, Kulkarni AB, Engle EC, Henderson CE, Etv1 Controls the Establishment of Non-overlapping Motor Innervation of Neighboring Facial Muscles during Development. Cell Rep. 2019 Oct 8;29(2):437-452.e4 |
1 | J:125106 Van de Putte T, Francis A, Nelles L, van Grunsven LA, Huylebroeck D, Neural crest-specific removal of Zfhx1b in mouse leads to a wide range of neurocristopathies reminiscent of Mowat-Wilson syndrome. Hum Mol Genet. 2007 Jun 15;16(12):1423-36 |
1 | J:274446 Wei W, Liu B, Jiang H, Jin K, Xiang M, Requirement of the Mowat-Wilson Syndrome Gene Zeb2 in the Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development. Mol Neurobiol. 2019 Mar;56(3):1719-1736 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Zfhx2 zinc finger homeobox 2 (Synonyms: zfh-5) | |
Results | Reference |
5* | J:106421 Komine Y, Nakamura K, Katsuki M, Yamamori T, Novel transcription factor zfh-5 is negatively regulated by its own antisense RNA in mouse brain. Mol Cell Neurosci. 2006 Feb;31(2):273-83 |
1* | J:195826 Komine Y, Takao K, Miyakawa T, Yamamori T, Behavioral abnormalities observed in Zfhx2-deficient mice. PLoS One. 2012;7(12):e53114 |
Zfhx2os zinc finger homeobox 2, opposite strand (Synonyms: Zfh-5 antisense, Zfhx2as) | |
Results | Reference |
5* | J:106421 Komine Y, Nakamura K, Katsuki M, Yamamori T, Novel transcription factor zfh-5 is negatively regulated by its own antisense RNA in mouse brain. Mol Cell Neurosci. 2006 Feb;31(2):273-83 |
Zfhx3 zinc finger homeobox 3 (Synonyms: A230102L03Rik, Atbf1, WBP9) | |
Results | Reference |
2* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
1* | J:195826 Komine Y, Takao K, Miyakawa T, Yamamori T, Behavioral abnormalities observed in Zfhx2-deficient mice. PLoS One. 2012;7(12):e53114 |
1* | J:136998 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL, Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. J Comp Neurol. 2007 Jun 20;502(6):1047-65 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Zfhx4 zinc finger homeodomain 4 (Synonyms: C130041O22Rik, Zfh-4, Zfh4) | |
Results | Reference |
1* | J:195826 Komine Y, Takao K, Miyakawa T, Yamamori T, Behavioral abnormalities observed in Zfhx2-deficient mice. PLoS One. 2012;7(12):e53114 |
1* | J:257654 Memic F, Knoflach V, Morarach K, Sadler R, Laranjeira C, Hjerling-Leffler J, Sundstrom E, Pachnis V, Marklund U, Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System. Gastroenterology. 2018 Feb;154(3):624-636 |
1 | J:316165 Nakamura E, Hata K, Takahata Y, Kurosaka H, Abe M, Abe T, Kihara M, Komori T, Kobayashi S, Murakami T, Inubushi T, Yamashiro T, Yamamoto S, Akiyama H, Kawaguchi M, Sakata N, Nishimura R, Zfhx4 regulates endochondral ossification as the transcriptional platform of Osterix in mice. Commun Biol. 2021 Nov 3;4(1):1258 |
2 | J:326576 Zhang M, Du S, Ou H, Cui R, Jiang N, Lin Y, Ge R, Ma D, Zhang J, Ablation of Zfhx4 results in early postnatal lethality by disrupting the respiratory center in mice. J Mol Cell Biol. 2021 Jul 6;13(3):210-224 |
Zfp24 zinc finger protein 24 (Synonyms: 3526401F17Rik, 5033419P20Rik, KOX17, ZF-12, Zfp191) | |
Results | Reference |
1* | J:130901 Khalfallah O, Faucon-Biguet N, Nardelli J, Meloni R, Mallet J, Expression of the transcription factor Zfp191 during embryonic development in the mouse. Gene Expr Patterns. 2008 Feb;8(3):148-154 |
Zfp28 zinc finger protein 28 (Synonyms: 2810438M17Rik, mkr-5, Zfp-28) | |
Results | Reference |
1 | J:292511 Gustafson EA, Seymour KA, Sigrist K, Rooij DGDE, Freiman RN, ZFP628 Is a TAF4b-Interacting Transcription Factor Required for Mouse Spermiogenesis. Mol Cell Biol. 2020 Mar 16;40(7) |
Zfp36 zinc finger protein 36 (Synonyms: Nup475, Tis11, Tristetraprolin, Ttp, Zfp-36) | |
Results | Reference |
1* | J:230794 Stumpo DJ, Trempus CS, Tucker CJ, Huang W, Li L, Kluckman K, Bortner DM, Blackshear PJ, Deficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolism. Development. 2016 Apr 15;143(8):1424-33 |
Zfp36l1 zinc finger protein 36, C3H type-like 1 (Synonyms: Brf1, cMG1, D530020L18Rik, TIS11b) | |
Results | Reference |
1 | J:100670 Blackshear PJ, Phillips RS, Ghosh S, Ramos SV, Richfield EK, Lai WS, Zfp36l3, a rodent X chromosome gene encoding a placenta-specific member of the Tristetraprolin family of CCCH tandem zinc finger proteins. Biol Reprod. 2005 Aug;73(2):297-307 |
1* | J:359452 Pang Y, Ruan X, Liu W, Hou L, Yin B, Shu P, Peng X, MicroRNA-495 Modulates Neuronal Layer Fate Determination by Targeting Tcf4. Int J Biol Sci. 2024;20(15):6207-6221 |
1* | J:230794 Stumpo DJ, Trempus CS, Tucker CJ, Huang W, Li L, Kluckman K, Bortner DM, Blackshear PJ, Deficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolism. Development. 2016 Apr 15;143(8):1424-33 |
1* | J:184831 Uchibe K, Shimizu H, Yokoyama S, Kuboki T, Asahara H, Identification of novel transcription-regulating genes expressed during murine molar development. Dev Dyn. 2012 Jul;241(7):1217-26 |
Zfp36l2 zinc finger protein 36, C3H type-like 2 (Synonyms: Brf2, ERF2, Tis11d) | |
Results | Reference |
1* | J:152911 Stumpo DJ, Broxmeyer HE, Ward T, Cooper S, Hangoc G, Chung YJ, Shelley WC, Richfield EK, Ray MK, Yoder MC, Aplan PD, Blackshear PJ, Targeted disruption of Zfp36l2, encoding a CCCH tandem zinc finger RNA-binding protein, results in defective hematopoiesis. Blood. 2009 Sep 17;114(12):2401-10 |
1* | J:230794 Stumpo DJ, Trempus CS, Tucker CJ, Huang W, Li L, Kluckman K, Bortner DM, Blackshear PJ, Deficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolism. Development. 2016 Apr 15;143(8):1424-33 |
Zfp36l3 zinc finger protein 36, C3H type-like 3 | |
Results | Reference |
1 | J:100670 Blackshear PJ, Phillips RS, Ghosh S, Ramos SV, Richfield EK, Lai WS, Zfp36l3, a rodent X chromosome gene encoding a placenta-specific member of the Tristetraprolin family of CCCH tandem zinc finger proteins. Biol Reprod. 2005 Aug;73(2):297-307 |
2* | J:230794 Stumpo DJ, Trempus CS, Tucker CJ, Huang W, Li L, Kluckman K, Bortner DM, Blackshear PJ, Deficiency of the placenta- and yolk sac-specific tristetraprolin family member ZFP36L3 identifies likely mRNA targets and an unexpected link to placental iron metabolism. Development. 2016 Apr 15;143(8):1424-33 |
Zfp37 zinc finger protein 37 (Synonyms: Tzn, Zfp-37) | |
Results | Reference |
1 | J:32842 Mazarakis N, Michalovich D, Karis A, Grosveld F, Galjart N, Zfp-37 is a member of the KRAB zinc finger gene family and is expressed in neurons of the developing and adult CNS. Genomics. 1996 Apr 15;33(2):247-57 |
Zfp40 zinc finger protein 40 (Synonyms: NTfin12, Zfp-40) | |
Results | Reference |
1* | J:3821 Noce T, Fujiwara Y, Ito M, Takeuchi T, Hashimoto N, Yamanouchi M, Higashinakagawa T, Fujimoto H, A novel murine zinc finger gene mapped within the tw18 deletion region expresses in germ cells and embryonic nervous system. Dev Biol. 1993 Feb;155(2):409-22 |
Zfp60 zinc finger protein 60 (Synonyms: 6330516O17Rik, Mfg-3, Mfg3) | |
Results | Reference |
3 | J:111426 Ganss B, Kobayashi H, The zinc finger transcription factor Zfp60 is a negative regulator of cartilage differentiation. J Bone Miner Res. 2002 Dec;17(12):2151-60 |
Zfp64 zinc finger protein 64 | |
Results | Reference |
1 | J:38274 Mack HG, Beck F, Bowtell DD, A search for a mammalian homologue of the Drosophila photoreceptor development gene glass yields Zfp64, a zinc finger encoding gene which maps to the distal end of mouse chromosome 2. Gene. 1997 Jan 31;185(1):11-7 |
Zfp92 zinc finger protein 92 | |
Results | Reference |
1* | J:33576 Levin ML, Chatterjee A, Pragliola A, Worley KC, Wehnert M, Zhuchenko O, Smith RF, Lee CC, Herman GE, A comparative transcription map of the murine bare patches (Bpa) and striated (Str) critical regions and human Xq28. Genome Res. 1996 Jun;6(6):465-77 |
Zfp143 zinc finger protein 143 (Synonyms: D7Ertd805e, KRAB14, pHZ-1, Staf, Zfp79, Zfp80-rs1) | |
Results | Reference |
1 | J:317822 Chern T, Achilleos A, Tong X, Hill MC, Saltzman AB, Reineke LC, Chaudhury A, Dasgupta SK, Redhead Y, Watkins D, Neilson JR, Thiagarajan P, Green JBA, Malovannaya A, Martin JF, Rosenblatt DS, Poche RA, Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy. Nat Commun. 2022 Jan 10;13(1):134 |
Zfp157 zinc finger protein 157 (Synonyms: 2610020C11Rik, A630094N24Rik, Roma) | |
Results | Reference |
1 | J:184505 Oliver CH, Khaled WT, Frend H, Nichols J, Watson CJ, The Stat6-regulated KRAB domain zinc finger protein Zfp157 regulates the balance of lineages in mammary glands and compensates for loss of Gata-3. Genes Dev. 2012 May 15;26(10):1086-97 |
1* | J:194068 Oliver CH, Nichols J, Watson CJ, The KRAB domain zinc finger protein, Zfp157, is expressed in multiple tissues during mouse embryogenesis and in specific cells in adult mammary gland and skin. Genesis. 2013 Mar;51(3):179-86 |
Zfp185 zinc finger protein 185 (Synonyms: P1-) | |
Results | Reference |
1* | J:42509 Heiss NS, Gloeckner G, Bachner D, Kioschis P, Klauck SM, Hinzmann B , Rosenthal A , Herman GE , Poustka A, Genomic structure of a novel LIM domain gene (ZNF185) in Xq28 and comparisons with the orthologous murine transcript. Genomics. 1997 Aug 1;43(3):329-38 |
2* | J:33576 Levin ML, Chatterjee A, Pragliola A, Worley KC, Wehnert M, Zhuchenko O, Smith RF, Lee CC, Herman GE, A comparative transcription map of the murine bare patches (Bpa) and striated (Str) critical regions and human Xq28. Genome Res. 1996 Jun;6(6):465-77 |
Zfp219 zinc finger protein 219 (Synonyms: 2010302A17Rik) | |
Results | Reference |
1* | J:328872 El Abdellaoui-Soussi F, Yunes-Leites PS, Lopez-Maderuelo D, Garcia-Marques F, Vazquez J, Redondo JM, Gomez-Del Arco P, Interplay between the Chd4/NuRD Complex and the Transcription Factor Znf219 Controls Cardiac Cell Identity. Int J Mol Sci. 2022 Aug 24;23(17) |
Zfp236 zinc finger protein 236 (Synonyms: LOC240456) | |
Results | Reference |
1 | J:331893 Yang J, Zhang L, Li Y, Chen M, Identifying key m(6)A-methylated lncRNAs and genes associated with neural tube defects via integrative MeRIP and RNA sequencing analyses. Front Genet. 2022;13:974357 |
Zfp263 zinc finger protein 263 (Synonyms: 1200014J04Rik, mFPM315, NT2) | |
Results | Reference |
1* | J:306453 Kajioka D, Suzuki K, Matsushita S, Hino S, Sato T, Takada S, Isono K, Takeo T, Kajimoto M, Nakagata N, Nakao M, Suyama M, DeFalco T, Miyagawa S, Yamada G, Sexual fate of murine external genitalia development: Conserved transcriptional competency for male-biased genes in both sexes. Proc Natl Acad Sci U S A. 2021 Jun 8;118(23):e2024067118 |
Zfp275 zinc finger protein 275 (Synonyms: 5430431L06Rik, DXBay20, DXHXS52, DXPas8) | |
Results | Reference |
1* | J:33576 Levin ML, Chatterjee A, Pragliola A, Worley KC, Wehnert M, Zhuchenko O, Smith RF, Lee CC, Herman GE, A comparative transcription map of the murine bare patches (Bpa) and striated (Str) critical regions and human Xq28. Genome Res. 1996 Jun;6(6):465-77 |
Zfp354c zinc finger protein 354C (Synonyms: 5330421P20Rik, AJ18, Kid3) | |
Results | Reference |
1* | J:60240 Watson RP, Tekki-Kessaris N, Boulter CA, Characterisation, chromosomal localisation and expression of the mouse Kid3 gene. Biochim Biophys Acta. 2000 Jan 31;1490(1-2):153-8 |
Zfp423 zinc finger protein 423 (Synonyms: ataxia1, Ebfaz, mKIAA0760, Roaz, Zfp104) | |
Results | Reference |
1 | J:236236 Hong CJ, Hamilton BA, Zfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium Function. PLoS Genet. 2016 Oct;12(10):e1006357 |
Zfp444 zinc finger protein 444 (Synonyms: 2810031J10Rik, 6230401O10Rik) | |
Results | Reference |
1* | J:316637 Strogantsev R, Krueger F, Yamazawa K, Shi H, Gould P, Goldman-Roberts M, McEwen K, Sun B, Pedersen R, Ferguson-Smith AC, Allele-specific binding of ZFP57 in the epigenetic regulation of imprinted and non-imprinted monoallelic expression. Genome Biol. 2015 May 30;16:112 |
Zfp445 zinc finger protein 445 (Synonyms: ZNF168) | |
Results | Reference |
1* | J:153743 Purcell P, Joo BW, Hu JK, Tran PV, Calicchio ML, O'Connell DJ, Maas RL, Tabin CJ, Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Zfp451 zinc finger protein 451 (Synonyms: 4930515K21Rik, 4933435G09Rik, Kiaa0576-hp, mKIAA1702) | |
Results | Reference |
1* | J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27 |
Zfp462 zinc finger protein 462 (Synonyms: 9430078C22Rik, Gt4-2, Zfpip) | |
Results | Reference |
2* | J:117873 Chang YS, Stoykova A, Chowdhury K, Gruss P, Graded expression of Zfp462 in the embryonic mouse cerebral cortex. Gene Expr Patterns. 2007 Feb;7(4):405-12 |
1* | J:121073 Laurent A, Bihan R, Deschamps S, Guerrier D, Dupe V, Omilli F, Burel A, Pellerin I, Identification of a new type of PBX1 partner that contains zinc finger motifs and inhibits the binding of HOXA9-PBX1 to DNA. Mech Dev. 2007 May;124(5):364-76 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Zfp469 zinc finger protein 469 (Synonyms: Gm22, LOC195209) | |
Results | Reference |
1* | J:263878 Aboudehen K, Farahani S, Kanchwala M, Chan SC, Avdulov S, Mickelson A, Lee D, Gearhart MD, Patel V, Xing C, Igarashi P, Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018 Jun 15;293(24):9388-9398 |
Zfp474 zinc finger protein 474 (Synonyms: 4933409D10Rik) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Zfp503 zinc finger protein 503 (Synonyms: B830002A16Rik, Nolz-1, Nolz1, ZNF503, Zpo2) | |
Results | Reference |
2 | J:339854 Chen SY, Liu FC, The Fgf9-Nolz1-Wnt2 axis regulates morphogenesis of the lung. Development. 2023 Aug 15;150(16):dev201827 |
1 | J:201551 Ko HA, Chen SY, Chen HY, Hao HJ, Liu FC, Cell type-selective expression of the zinc finger-containing gene Nolz-1/Zfp503 in the developing mouse striatum. Neurosci Lett. 2013 Aug 26;548:44-9 |
1 | J:328873 Shang Z, Yang L, Wang Z, Tian Y, Gao Y, Su Z, Guo R, Li W, Liu G, Li X, Yang Z, Li Z, Zhang Z, The transcription factor Zfp503 promotes the D1 MSN identity and represses the D2 MSN identity. Front Cell Dev Biol. 2022;10:948331 |
2 | J:321980 Su Z, Wang Z, Lindtner S, Yang L, Shang Z, Tian Y, Guo R, You Y, Zhou W, Rubenstein JL, Yang Z, Zhang Z, Dlx1/2-dependent expression of Meis2 promotes neuronal fate determination in the mammalian striatum. Development. 2022 Feb 15;149(4):dev200035 |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
Zfp521 zinc finger protein 521 (Synonyms: B930086A16Rik, Evi3) | |
Results | Reference |
1 | J:282571 Zhang Z, Wei S, Du H, Su Z, Wen Y, Shang Z, Song X, Xu Z, You Y, Yang Z, Zfhx3 is required for the differentiation of late born D1-type medium spiny neurons. Exp Neurol. 2019 Dec;322:113055 |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Zfp536 zinc finger protein 536 (Synonyms: 9630010P11Rik, mKIAA0390) | |
Results | Reference |
1 | J:256883 Zhou J, Wang R, Zhang J, Zhu L, Liu W, Lu S, Chen P, Li H, Yin B, Yuan J, Qiang B, Shu P, Peng X, Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168 |
Zfp541 zinc finger protein 541 (Synonyms: EG666528) | |
Results | Reference |
2 | J:307864 Horisawa-Takada Y, Kodera C, Takemoto K, Sakashita A, Horisawa K, Maeda R, Shimada R, Usuki S, Fujimura S, Tani N, Matsuura K, Akiyama T, Suzuki A, Niwa H, Tachibana M, Ohba T, Katabuchi H, Namekawa SH, Araki K, Ishiguro KI, Meiosis-specific ZFP541 repressor complex promotes developmental progression of meiotic prophase towards completion during mouse spermatogenesis. Nat Commun. 2021 Jun 1;12(1):3184 |
1* | J:306305 Oura S, Koyano T, Kodera C, Horisawa-Takada Y, Matsuyama M, Ishiguro KI, Ikawa M, KCTD19 and its associated protein ZFP541 are independently essential for meiosis in male mice. PLoS Genet. 2021 May;17(5):e1009412 |
Zfp568 zinc finger protein 568 (Synonyms: chato, LOC381866) | |
Results | Reference |
1* | J:192224 Chien HC, Wang HY, Su YN, Lai KY, Lu LC, Chen PC, Tsai SF, Wu CI, Hsieh WS, Shen CK, Targeted disruption in mice of a neural stem cell-maintaining, KRAB-Zn finger-encoding gene that has rapidly evolved in the human lineage. PLoS One. 2012;7(10):e47481 |
Zfp703 zinc finger protein 703 (Synonyms: 1110032O19Rik, Csmn1, End2, Zeppo1) | |
Results | Reference |
1 | J:72872 Bain G, Mansergh FC, Wride MA, Hance JE, Isogawa A, Rancourt SL, Ray WJ, Yoshimura Y, Tsuzuki T, Gottlieb DI, Rancourt DE, ES cell neural differentiation reveals a substantial number of novel ESTs. Funct Integr Genomics. 2000 Sep;1(2):127-139 |
Zfp750 zinc finger protein 750 (Synonyms: A030007D23Rik) | |
Results | Reference |
1 | J:341642 Schwartz B, Levi H, Menon G, Maria R, Upcher A, Kotlovski Y, Oss-Ronen L, Cohen I, ZNF750 Regulates Skin Barrier Function by Driving Cornified Envelope and Lipid Processing Pathways. J Invest Dermatol. 2023 Sep 3; |
Zfp819 zinc finger protein 819 (Synonyms: 4930427I11Rik, 4933405K07Rik) | |
Results | Reference |
1 | J:356085 Wang J, Tian GG, Zheng Z, Li B, Xing Q, Wu J, Comprehensive Transcriptomic Analysis of Mouse Gonadal Development Involving Sexual Differentiation, Meiosis and Gametogenesis. Biol Proced Online. 2019;21:20 |
Zfpm1 zinc finger protein, multitype 1 (Synonyms: Fog1, Friend of GATA-1) | |
Results | Reference |
1* | J:86790 Gitler AD, Lu MM, Jiang YQ, Epstein JA, Gruber PJ, Molecular markers of cardiac endocardial cushion development. Dev Dyn. 2003 Dec;228(4):643-50 |
1* | J:271614 Gudmundsdottir B, Gudmundsson KO, Klarmann KD, Singh SK, Sun L, Singh S, Du Y, Coppola V, Stockwin L, Nguyen N, Tessarollo L, Thorsteinsson L, Sigurjonsson OE, Gudmundsson S, Rafnar T, Tisdale JF, Keller JR, POGZ Is Required for Silencing Mouse Embryonic beta-like Hemoglobin and Human Fetal Hemoglobin Expression. Cell Rep. 2018 Jun 12;23(11):3236-3248 |
Zfpm2 zinc finger protein, multitype 2 (Synonyms: B330005D23Rik, FOG-2, FOG2) | |
Results | Reference |
1* | J:100119 Ackerman KG, Herron BJ, Vargas SO, Huang H, Tevosian SG, Kochilas L, Rao C, Pober BR, Babiuk RP, Epstein JA, Greer JJ, Beier DR, Fog2 is required for normal diaphragm and lung development in mice and humans. PLoS Genet. 2005 Jul;1(1):e10 |
1* | J:86790 Gitler AD, Lu MM, Jiang YQ, Epstein JA, Gruber PJ, Molecular markers of cardiac endocardial cushion development. Dev Dyn. 2003 Dec;228(4):643-50 |
1* | J:151488 Kim GH, Samant SA, Earley JU, Svensson EC, Translational control of FOG-2 expression in cardiomyocytes by microRNA-130a. PLoS One. 2009;4(7):e6161 |
1 | J:315293 Kumamoto T, Toma K, Gunadi, McKenna WL, Kasukawa T, Katzman S, Chen B, Hanashima C, Foxg1 coordinates the switch from nonradially to radially migrating glutamatergic subtypes in the neocortex through spatiotemporal repression. Cell Rep. 2013 Mar 28;3(3):931-45 |
1* | J:347585 Leon NY, Le TNU, Garvie A, Wong LH, Bagheri-Fam S, Harley VR, Y chromosome damage underlies testicular abnormalities in ATR-X syndrome. iScience. 2024 May 17;27(5):109629 |
1* | J:53717 Svensson EC, Tufts RL, Polk CE, Leiden JM, Molecular cloning of FOG-2: a modulator of transcription factor GATA-4 in cardiomyocytes. Proc Natl Acad Sci U S A. 1999 Feb 2;96(3):956-61 |
Zfta zinc finger translocation associated (Synonyms: 2700081O15Rik) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Zfy1 zinc finger protein 1, Y-linked (Synonyms: Zfy-1) | |
Results | Reference |
1* | J:40018 Koopman P, Gubbay J, Collignon J, Lovell-Badge R, Zfy gene expression patterns are not compatible with a primary role in mouse sex determination. Nature. 1989 Dec 21-28;342(6252):940-2 |
Zglp1 zinc finger, GATA-like protein 1 (Synonyms: Glp1) | |
Results | Reference |
1* | J:180844 Strauss TJ, Castrillon DH, Hammes SR, GATA-like protein-1 (GLP-1) is required for normal germ cell development during embryonic oogenesis. Reproduction. 2011 Feb;141(2):173-81 |
Zic1 zinc finger protein of the cerebellum 1 (Synonyms: odd-paired homolog) | |
Results | Reference |
1* | J:282348 Dasgupta K, Chung JU, Asam K, Jeong J, Molecular patterning of the embryonic cranial mesenchyme revealed by genome-wide transcriptional profiling. Dev Biol. 2019 Nov 15;455(2):434-448 |
1 | J:164404 Garcia-Frigola C, Herrera E, Zic2 regulates the expression of Sert to modulate eye-specific refinement at the visual targets. EMBO J. 2010 Sep 15;29(18):3170-83 |
1 | J:167212 Gibson P, Tong Y, Robinson G, Thompson MC, Currle DS, Eden C, Kranenburg TA, Hogg T, Poppleton H, Martin J, Finkelstein D, Pounds S, Weiss A, Patay Z, Scoggins M, Ogg R, Pei Y, Yang ZJ, Brun S, Lee Y, Zindy F, Lindsey JC, Taketo MM, Boop FA, Sanford RA, Gajjar A, Clifford SC, Roussel MF, McKinnon PJ, Gutmann DH, Ellison DW, Wechsler-Reya R, Gilbertson RJ, Subtypes of medulloblastoma have distinct developmental origins. Nature. 2010 Dec 23;468(7327):1095-9 |
2* | J:85445 Herrera E, Brown L, Aruga J, Rachel RA, Dolen G, Mikoshiba K, Brown S, Mason CA, Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell. 2003 Sep 5;114(5):545-57 |
2 | J:134970 Inoue T, Ogawa M, Mikoshiba K, Aruga J, Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly. J Neurosci. 2008 Apr 30;28(18):4712-25 |
2 | J:121744 Inoue T, Ota M, Ogawa M, Mikoshiba K, Aruga J, Zic1 and Zic3 regulate medial forebrain development through expansion of neuronal progenitors. J Neurosci. 2007 May 16;27(20):5461-73 |
1 | J:143462 Liu Z, Li H, Hu X, Yu L, Liu H, Han R, Colella R, Mower GD, Chen Y, Qiu M, Control of precerebellar neuron development by Olig3 bHLH transcription factor. J Neurosci. 2008 Oct 1;28(40):10124-33 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
Zic2 zinc finger protein of the cerebellum 2 (Synonyms: GENA 29, Ku, odd-paired homolog) | |
Results | Reference |
1 | J:240943 Bruce FM, Brown S, Smith JN, Fuerst PG, Erskine L, DSCAM promotes axon fasciculation and growth in the developing optic pathway. Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1702-1707 |
2 | J:239874 Christ A, Christa A, Klippert J, Eule JC, Bachmann S, Wallace VA, Hammes A, Willnow TE, LRP2 Acts as SHH Clearance Receptor to Protect the Retinal Margin from Mitogenic Stimuli. Dev Cell. 2015 Oct 12;35(1):36-48 |
1 | J:266267 Clements R, Wright KM, Retinal ganglion cell axon sorting at the optic chiasm requires dystroglycan. Dev Biol. 2018 Oct 15;442(2):210-219 |
1* | J:350259 Fernandez-Nogales M, Lopez-Cascales MT, Murcia-Belmonte V, Escalante A, Fernandez-Albert J, Munoz-Viana R, Barco A, Herrera E, Multiomic Analysis of Neurons with Divergent Projection Patterns Identifies Novel Regulators of Axon Pathfinding. Adv Sci (Weinh). 2022 Oct;9(29):e2200615 |
1* | J:339296 Fries M, Brown TW, Jolicoeur C, Boulan B, Boudreau-Pinsonneault C, Javed A, Abram P, Cayouette M, Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections. Cell Rep. 2023 Aug 16;42(8):112985 |
1* | J:134680 Garcia-Frigola C, Carreres MI, Vegar C, Mason C, Herrera E, Zic2 promotes axonal divergence at the optic chiasm midline by EphB1-dependent and -independent mechanisms. Development. 2008 May;135(10):1833-41 |
4* | J:85445 Herrera E, Brown L, Aruga J, Rachel RA, Dolen G, Mikoshiba K, Brown S, Mason CA, Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell. 2003 Sep 5;114(5):545-57 |
2 | J:94392 Herrera E, Marcus R, Li S, Williams SE, Erskine L, Lai E, Mason C, Foxd1 is required for proper formation of the optic chiasm. Development. 2004 Nov;131(22):5727-39 |
2 | J:134970 Inoue T, Ogawa M, Mikoshiba K, Aruga J, Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly. J Neurosci. 2008 Apr 30;28(18):4712-25 |
2 | J:121744 Inoue T, Ota M, Ogawa M, Mikoshiba K, Aruga J, Zic1 and Zic3 regulate medial forebrain development through expansion of neuronal progenitors. J Neurosci. 2007 May 16;27(20):5461-73 |
1 | J:270927 Kridsada K, Niu J, Haldipur P, Wang Z, Ding L, Li JJ, Lindgren AG, Herrera E, Thomas GM, Chizhikov VV, Millen KJ, Luo W, Roof Plate-Derived Radial Glial-like Cells Support Developmental Growth of Rapidly Adapting Mechanoreceptor Ascending Axons. Cell Rep. 2018 Jun 5;23(10):2928-2941 |
1 | J:241892 Marcucci F, Murcia-Belmonte V, Wang Q, Coca Y, Ferreiro-Galve S, Kuwajima T, Khalid S, Ross ME, Mason C, Herrera E, The Ciliary Margin Zone of the Mammalian Retina Generates Retinal Ganglion Cells. Cell Rep. 2016 Dec 20;17(12):3153-3164 |
1* | J:269981 Marcucci F, Soares CA, Mason C, Distinct timing of neurogenesis of ipsilateral and contralateral retinal ganglion cells. J Comp Neurol. 2019 Jan 1;527(1):212-224 |
1 | J:196051 Moldrich RX, Gobius I, Pollak T, Zhang J, Ren T, Brown L, Mori S, De Juan Romero C, Britanova O, Tarabykin V, Richards LJ, Molecular regulation of the developing commissural plate. J Comp Neurol. 2010 Sep 15;518(18):3645-61 |
1* | J:278827 Murcia-Belmonte V, Coca Y, Vegar C, Negueruela S, de Juan Romero C, Valino AJ, Sala S, DaSilva R, Kania A, Borrell V, Martinez LM, Erskine L, Herrera E, A Retino-retinal Projection Guided by Unc5c Emerged in Species with Retinal Waves. Curr Biol. 2019 Apr 1;29(7):1149-1160.e4 |
1 | J:160165 Pinter R, Hindges R, Perturbations of microRNA function in mouse dicer mutants produce retinal defects and lead to aberrant axon pathfinding at the optic chiasm. PLoS One. 2010;5(4):e10021 |
1 | J:123264 Quina LA, Pak W, Lanier J, Banwait P, Gratwick K, Liu Y, Velasquez T, O'Leary DD, Goulding M, Turner EE, Brn3a-expressing retinal ganglion cells project specifically to thalamocortical and collicular visual pathways. J Neurosci. 2005 Dec 14;25(50):11595-604 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1* | J:151233 Trimarchi JM, Cho SH, Cepko CL, Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Dev Dyn. 2009 Sep;238(9):2327-9 |
1 | J:255944 Wang Q, Marcucci F, Cerullo I, Mason C, Ipsilateral and Contralateral Retinal Ganglion Cells Express Distinct Genes during Decussation at the Optic Chiasm. eNeuro. 2016 Nov-Dec;3(6):ENEURO.0169-16.2016 |
1 | J:256746 Wang X, Shan X, Gregory-Evans CY, A mouse model of aniridia reveals the in vivo downstream targets of Pax6 driving iris and ciliary body development in the eye. Biochim Biophys Acta. 2017 Jan;1863(1):60-67 |
1 | J:122943 Williams SE, Grumet M, Colman DR, Henkemeyer M, Mason CA, Sakurai T, A role for Nr-CAM in the patterning of binocular visual pathways. Neuron. 2006 May 18;50(4):535-47 |
1 | J:199791 Young TR, Bourke M, Zhou X, Oohashi T, Sawatari A, Fassler R, Leamey CA, Ten-m2 Is Required for the Generation of Binocular Visual Circuits. J Neurosci. 2013 Jul 24;33(30):12490-509 |
Zic3 zinc finger protein of the cerebellum 3 (Synonyms: Ka) | |
Results | Reference |
1* | J:85445 Herrera E, Brown L, Aruga J, Rachel RA, Dolen G, Mikoshiba K, Brown S, Mason CA, Zic2 patterns binocular vision by specifying the uncrossed retinal projection. Cell. 2003 Sep 5;114(5):545-57 |
2 | J:134970 Inoue T, Ogawa M, Mikoshiba K, Aruga J, Zic deficiency in the cortical marginal zone and meninges results in cortical lamination defects resembling those in type II lissencephaly. J Neurosci. 2008 Apr 30;28(18):4712-25 |
2 | J:121744 Inoue T, Ota M, Ogawa M, Mikoshiba K, Aruga J, Zic1 and Zic3 regulate medial forebrain development through expansion of neuronal progenitors. J Neurosci. 2007 May 16;27(20):5461-73 |
1 | J:34807 Miyata T, Nakajima K, Aruga J, Takahashi S, Ikenaka K, Mikoshiba K, Ogawa M, Distribution of a reeler gene-related antigen in the developing cerebellum: an immunohistochemical study with an allogeneic antibody CR-50 on normal and reeler mice. J Comp Neurol. 1996 Aug 19;372(2):215-28 |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
Zic4 zinc finger protein of the cerebellum 4 | |
Results | Reference |
1 | J:295031 Li Z, Pratt T, Price DJ, Zic4-Lineage Cells Increase Their Contribution to Visual Thalamic Nuclei during Murine Embryogenesis If They Are Homozygous or Heterozygous for Loss of Pax6 Function. eNeuro. 2018 Sep-Oct;5(5):ENEURO.0367-18.2018 |
1* | J:332131 Perera SN, Williams RM, Lyne R, Stubbs O, Buehler DP, Sauka-Spengler T, Noda M, Micklem G, Southard-Smith EM, Baker CVH, Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach. Glia. 2020 Dec;68(12):2550-2584 |
Zic5 zinc finger protein of the cerebellum 5 (Synonyms: 1700049L20Rik, odd-paired related, Opr) | |
Results | Reference |
1 | J:125931 Muhlfriedel S, Kirsch F, Gruss P, Chowdhury K, Stoykova A, Novel genes differentially expressed in cortical regions during late neurogenesis. Eur J Neurosci. 2007 Jul;26(1):33-50 |
Zim1 zinc finger, imprinted 1 | |
Results | Reference |
1* | J:54552 Kim J, Lu X, Stubbs L, Zim1, a maternally expressed mouse Kruppel-type zinc-finger gene located in proximal chromosome 7. Hum Mol Genet. 1999 May;8(5):847-54 |
1 | J:298882 Roome RB, Bourojeni FB, Mona B, Rastegar-Pouyani S, Blain R, Dumouchel A, Salesse C, Thompson WS, Brookbank M, Gitton Y, Tessarollo L, Goulding M, Johnson JE, Kmita M, Chedotal A, Kania A, Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans. Cell Rep. 2020 Nov 24;33(8):108425 |
Zmiz2 zinc finger, MIZ-type containing 2 (Synonyms: 2410117E06Rik, D11Bwg0280e, Zimp7) | |
Results | Reference |
1* | J:155888 Rodriguez-Magadan H, Ramirez L, Schnabel D, Vazquez M, Lomeli H, Sexually dimorphic gene expression of the Zimp7 and Zimp10 genes in embryonic gonads. Gene Expr Patterns. 2010 Jan;10(1):16-23 |
Zmynd10 zinc finger, MYND domain containing 10 (Synonyms: Blu) | |
Results | Reference |
1* | J:240319 Stauber M, Weidemann M, Dittrich-Breiholz O, Lobschat K, Alten L, Mai M, Beckers A, Kracht M, Gossler A, Identification of FOXJ1 effectors during ciliogenesis in the foetal respiratory epithelium and embryonic left-right organiser of the mouse. Dev Biol. 2017 Mar 15;423(2):170-188 |
Zng1 Zn regulated GTPase metalloprotein activator 1 (Synonyms: Cbwd1, MGC:28027, MGC:59411, Zng1) | |
Results | Reference |
1* | J:326010 Kanda S, Ohmuraya M, Akagawa H, Horita S, Yoshida Y, Kaneko N, Sugawara N, Ishizuka K, Miura K, Harita Y, Yamamoto T, Oka A, Araki K, Furukawa T, Hattori M, Deletion in the Cobalamin Synthetase W Domain-Containing Protein 1 Gene Is associated with Congenital Anomalies of the Kidney and Urinary Tract. J Am Soc Nephrol. 2020 Jan;31(1):139-147 |
Znhit1 zinc finger, HIT domain containing 1 (Synonyms: 2700001K05Rik) | |
Results | Reference |
1 | J:329947 Wei W, Tang X, Jiang N, Ni C, He H, Sun S, Yu M, Yu C, Qiu M, Yan D, Zhou Z, Song Y, Liu H, Zhao B, Lin X, Chromatin remodeler Znhit1 controls bone morphogenetic protein signaling in embryonic lung tissue branching. J Biol Chem. 2022 Sep 14;298(10):102490 |
1* | J:305946 Xu M, Yao J, Shi Y, Yi H, Zhao W, Lin X, Yang Z, The SRCAP chromatin remodeling complex promotes oxidative metabolism during prenatal heart development. Development. 2021 Apr 15;148(8):dev199026 |
Zscan10 zinc finger and SCAN domain containing 10 (Synonyms: Zfp206, Zscan10) | |
Results | Reference |
2* | J:126045 Wang ZX, Kueh JL, Teh CH, Rossbach M, Lim L, Li P, Wong KY, Lufkin T, Robson P, Stanton LW, Zfp206 is a transcription factor that controls pluripotency of embryonic stem cells. Stem Cells. 2007 Sep;25(9):2173-82 |
Zswim6 zinc finger SWIM-type containing 6 (Synonyms: 2900036G02Rik, mKIAA1577) | |
Results | Reference |
1* | J:157819 Shimogori T, Lee DA, Miranda-Angulo A, Yang Y, Wang H, Jiang L, Yoshida AC, Kataoka A, Mashiko H, Avetisyan M, Qi L, Qian J, Blackshaw S, A genomic atlas of mouse hypothalamic development. Nat Neurosci. 2010;13(6):767-75 |
1 | J:259070 Tischfield DJ, Saraswat DK, Furash A, Fowler SC, Fuccillo MV, Anderson SA, Loss of the neurodevelopmental gene Zswim6 alters striatal morphology and motor regulation. Neurobiol Dis. 2017 Jul;103:174-183 |
Zxdc ZXD family zinc finger C (Synonyms: B930086F11Rik, MGC:7160) | |
Results | Reference |
1* | J:99372 van der Zwaag B, Burbach JP, Scharfe C, Oefner PJ, Brunner HG, Padberg GW, van Bokhoven H, Identifying new candidate genes for hereditary facial paresis on chromosome 3q21-q22 by RNA in situ hybridization in mouse. Genomics. 2005 Jul;86(1):55-67 |
1 | J:316098 Zhao J, Lu P, Wan C, Huang Y, Cui M, Yang X, Hu Y, Zheng Y, Dong J, Wang M, Zhang S, Liu Z, Bian S, Wang X, Wang R, Ren S, Wang D, Yao Z, Chang G, Tang F, Zhao XY, Cell-fate transition and determination analysis of mouse male germ cells throughout development. Nat Commun. 2021 Nov 25;12(1):6839 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 03/25/2025 MGI 6.24 |
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