Gene Expression Literature Summary

Assay

Age

Immunohistochemistry (whole mount)

9.5 DPC

26 matching records from 26 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Acta2 actin alpha 2, smooth muscle, aorta (Synonyms: 0610041G09Rik, Actvs, alphaSMA, a-SMA, SMAalpha, SMalphaA)
Results	Reference
1	J:50951 Bader BL, Rayburn H, Crowley D, Hynes RO, Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins. Cell. 1998 Nov 13;95(4):507-19
1	J:104401 Braren R, Hu H, Kim YH, Beggs HE, Reichardt LF, Wang R, Endothelial FAK is essential for vascular network stability, cell survival, and lamellipodial formation. J Cell Biol. 2006 Jan 2;172(1):151-62
1*	J:221094 Carracedo S, Sacher F, Brandes G, Braun U, Leitges M, Redundant role of protein kinase C delta and epsilon during mouse embryonic development. PLoS One. 2014;9(8):e103686
1	J:341539 Chiang IK, Humphrey D, Mills RJ, Kaltzis P, Pachauri S, Graus M, Saha D, Wu Z, Young P, Sim CB, Davidson T, Hernandez-Garcia A, Shaw CA, Renwick A, Scott DA, Porrello ER, Wong ES, Hudson JE, Red-Horse K, Del Monte-Nieto G, Francois M, Sox7-positive endothelial progenitors establish coronary arteries and govern ventricular compaction. EMBO Rep. 2023 Oct 9;24(10):e55043
1	J:208348 Fantin A, Herzog B, Mahmoud M, Yamaji M, Plein A, Denti L, Ruhrberg C, Zachary I, Neuropilin 1 (NRP1) hypomorphism combined with defective VEGF-A binding reveals novel roles for NRP1 in developmental and pathological angiogenesis. Development. 2014 Feb;141(3):556-62
1*	J:93580 Hallaq H, Pinter E, Enciso J, McGrath J, Zeiss C, Brueckner M, Madri J, Jacobs HC, Wilson CM, Vasavada H, Jiang X, Bogue CW, A null mutation of Hhex results in abnormal cardiac development, defective vasculogenesis and elevated Vegfa levels. Development. 2004 Oct;131(20):5197-209
1	J:321521 Hong L, Li N, Gasque V, Mehta S, Ye L, Wu Y, Li J, Gewies A, Ruland J, Hirschi KK, Eichmann A, Hendry C, van Dijk D, Mani A, Prdm6 controls heart development by regulating neural crest cell differentiation and migration. JCI Insight. 2022 Feb 2;7(4):e156046
1*	J:107401 Jadrich JL, O'connor MB, Coucouvanis E, The TGF{beta} activated kinase TAK1 regulates vascular development in vivo. Development. 2006 Apr;133(8):1529-41
1	J:93125 Krebs LT, Shutter JR, Tanigaki K, Honjo T, Stark KL, Gridley T, Haploinsufficient lethality and formation of arteriovenous malformations in Notch pathway mutants. Genes Dev. 2004 Oct 15;18(20):2469-73
1*	J:86515 Lai L, Bohnsack BL, Niederreither K, Hirschi KK, Retinoic acid regulates endothelial cell proliferation during vasculogenesis. Development. 2003 Dec;130(26):6465-6474
1	J:155850 Lee D, Park C, Lee H, Lugus JJ, Kim SH, Arentson E, Chung YS, Gomez G, Kyba M, Lin S, Janknecht R, Lim DS, Choi K, ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell. 2008 May 8;2(5):497-507
1	J:84789 Li S, Wang DZ, Wang Z, Richardson JA, Olson EN, The serum response factor coactivator myocardin is required for vascular smooth muscle development. Proc Natl Acad Sci U S A. 2003 Aug 5;100(16):9366-70
1	J:337546 Liu H, Lu P, He S, Luo Y, Fang Y, Benkaci S, Wu B, Wang Y, Zhou B, beta-Catenin regulates endocardial cushion growth by suppressing p21. Life Sci Alliance. 2023 Sep;6(9)
1	J:245082 Losa M, Latorre V, Andrabi M, Ladam F, Sagerstrom C, Novoa A, Zarrineh P, Bridoux L, Hanley NA, Mallo M, Bobola N, A tissue-specific, Gata6-driven transcriptional program instructs remodeling of the mature arterial tree. Elife. 2017 Sep 27;6:e31362
1	J:306230 Peacock HM, Tabibian A, Criem N, Caolo V, Hamard L, Deryckere A, Haefliger JA, Kwak BR, Zwijsen A, Jones EAV, Impaired SMAD1/5 Mechanotransduction and Cx37 (Connexin37) Expression Enable Pathological Vessel Enlargement and Shunting. Arterioscler Thromb Vasc Biol. 2020 Apr;40(4):e87-e104
1	J:199892 Rhee S, Guerrero-Zayas MI, Wallingford MC, Ortiz-Pineda P, Mager J, Tremblay KD, Visceral endoderm expression of Yin-Yang1 (YY1) is required for VEGFA maintenance and yolk sac development. PLoS One. 2013;8(3):e58828
1*	J:334465 Sindram E, Caballero-Oteyza A, Kogata N, Huang S, Alizadeh Z, Gamez-Diaz L, Fazlollhi MR, Peng X, Grimbacher B, Way M, Proietti M, ARPC5 deficiency leads to severe early-onset systemic inflammation and mortality. Dis Model Mech. 2023 Jul 1;16(7)
1*	J:191486 Sivina M, Yamada T, Park CS, Puppi M, Coskun S, Hirschi K, Lacorazza HD, The transcription factor E74-like factor controls quiescence of endothelial cells and their resistance to myeloablative treatments in bone marrow. Arterioscler Thromb Vasc Biol. 2011 May;31(5):1185-91
1	J:186037 Smart N, Dube KN, Riley PR, Identification of Thymosin beta4 as an effector of Hand1-mediated vascular development. Nat Commun. 2010;1:46
1	J:239945 Souilhol C, Perea-Gomez A, Camus A, Beck-Cormier S, Vandormael-Pournin S, Escande M, Collignon J, Cohen-Tannoudji M, NOTCH activation interferes with cell fate specification in the gastrulating mouse embryo. Development. 2015 Nov 01;142(21):3649-60
1	J:82356 Takahashi T, Takahashi K, St John PL, Fleming PA, Tomemori T, Watanabe T, Abrahamson DR, Drake CJ, Shirasawa T, Daniel TO, A mutant receptor tyrosine phosphatase, CD148, causes defects in vascular development. Mol Cell Biol. 2003 Mar;23(5):1817-31
1	J:345100 Talvi S, Jokinen J, Sipila K, Rappu P, Zhang FP, Poutanen M, Rantakari P, Heino J, Embigin deficiency leads to delayed embryonic lung development and high neonatal mortality in mice. iScience. 2024 Feb 16;27(2):108914
1*	J:65521 Urness LD, Sorensen LK, Li DY, Arteriovenous malformations in mice lacking activin receptor-like kinase-1. Nat Genet. 2000 Nov;26(3):328-31
1*	J:238642 Vrbacky M, Kovalcikova J, Chawengsaksophak K, Beck IM, Mracek T, Nuskova H, Sedmera D, Papousek F, Kolar F, Sobol M, Hozak P, Sedlacek R, Houstek J, Knockout of Tmem70 alters biogenesis of ATP synthase and leads to embryonal lethality in mice. Hum Mol Genet. 2016 Nov 01;25(21):4674-4685
1*	J:84651 Yamazaki D, Suetsugu S, Miki H, Kataoka Y, Nishikawa S, Fujiwara T, Yoshida N, Takenawa T, WAVE2 is required for directed cell migration and cardiovascular development. Nature. 2003 Jul 24;424(6947):452-6
1	J:70892 Ylikorkala A, Rossi DJ, Korsisaari N, Luukko K, Alitalo K, Henkemeyer M, Makela TP, Vascular abnormalities and deregulation of VEGF in Lkb1-deficient mice. Science. 2001 Aug 17;293(5533):1323-6

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