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Gene Expression Literature Summary
Assay
Age
RT-PCR
9.5 DPC

6 matching records from 6 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Grhl2  grainyhead like transcription factor 2   (Synonyms: 0610015A08Rik, BOM, clft3, grainyheadlike, Tcfcp2l3)
Results  Reference
1J:170759 Brouns MR, De Castro SC, Terwindt-Rouwenhorst EA, Massa V, Hekking JW, Hirst CS, Savery D, Munts C, Partridge D, Lamers W, Kohler E, van Straaten HW, Copp AJ, Greene ND, Over-expression of Grhl2 causes spina bifida in the Axial defects mutant mouse. Hum Mol Genet. 2011 Apr 15;20(8):1536-46
1J:343442 Crane-Smith Z, De Castro SCP, Nikolopoulou E, Wolujewicz P, Smedley D, Lei Y, Mather E, Santos C, Hopkinson M, Pitsillides AA, Finnell RH, Ross ME, Copp AJ, Greene NDE, A non-coding insertional mutation of Grhl2 causes gene over-expression and multiple structural anomalies including cleft palate, spina bifida and encephalocele. Hum Mol Genet. 2023 Aug 26;32(17):2681-2692
1J:269325 De Castro SCP, Gustavsson P, Marshall AR, Gordon WM, Galea G, Nikolopoulou E, Savery D, Rolo A, Stanier P, Andersen B, Copp AJ, Greene NDE, Overexpression of Grainyhead-like 3 causes spina bifida and interacts genetically with mutant alleles of Grhl2 and Vangl2 in mice. Hum Mol Genet. 2018 Dec 15;27(24):4218-4230
1J:279661 Nikolopoulou E, Hirst CS, Galea G, Venturini C, Moulding D, Marshall AR, Rolo A, De Castro SCP, Copp AJ, Greene NDE, Spinal neural tube closure depends on regulation of surface ectoderm identity and biomechanics by Grhl2. Nat Commun. 2019 Jun 6;10(1):2487
1J:169829 Pyrgaki C, Liu A, Niswander L, Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion. Dev Biol. 2011 May 1;353(1):38-49
1*J:164805 Rifat Y, Parekh V, Wilanowski T, Hislop NR, Auden A, Ting SB, Cunningham JM, Jane SM, Regional neural tube closure defined by the Grainy head-like transcription factors. Dev Biol. 2010 Sep 15;345(2):237-45
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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08/02/2024
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