Assay
Age
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Immunohistochemistry (section)
Postnatal
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Lama1 laminin, alpha 1 (Synonyms: Lama) | |
Results | Reference |
1 | J:176572 Ackroyd MR, Whitmore C, Prior S, Kaluarachchi M, Nikolic M, Mayer U, Muntoni F, Brown SC, Fukutin-related protein alters the deposition of laminin in the eye and brain. J Neurosci. 2011 Sep 7;31(36):12927-35 |
1 | J:232500 Andrae J, Gouveia L, Gallini R, He L, Fredriksson L, Nilsson I, Johansson BR, Eriksson U, Betsholtz C, A role for PDGF-C/PDGFRalpha signaling in the formation of the meningeal basement membranes surrounding the cerebral cortex. Biol Open. 2016;5(4):461-74 |
1 | J:63137 Andrews KL, Betsuyaku T, Rogers S, Shipley JM, Senior RM, Miner JH, Gelatinase B (MMP-9) is not essential in the normal kidney and does not influence progression of renal disease in a mouse model of alport syndrome. Am J Pathol. 2000 Jul;157(1):303-11 |
1 | J:96910 Blaess S, Graus-Porta D, Belvindrah R, Radakovits R, Pons S, Littlewood-Evans A, Senften M, Guo H, Li Y, Miner JH, Reichardt LF, Muller U, Beta1-integrins are critical for cerebellar granule cell precursor proliferation. J Neurosci. 2004 Mar 31;24(13):3402-12 |
1 | J:26685 Frojdman K, Ekblom P, Sorokin L, Yagi A, Pelliniemi LJ, Differential distribution of laminin chains in the development and sex differentiation of mouse internal genitalia. Int J Dev Biol. 1995 Apr;39(2):335-44 |
1* | J:345230 Garis M, Meyer MD, Lwigale P, Expression of Nephronectin in the Descemet's membrane of mouse corneas during development and adult homeostasis. Exp Eye Res. 2024 Jan 19;240:109797 |
1* | J:154510 Gebauer JM, Keene DR, Olsen BR, Sorokin LM, Paulsson M, Wagener R, Mouse AMACO, a kidney and skin basement membrane associated molecule that mediates RGD-dependent cell attachment. Matrix Biol. 2009 Oct;28(8):456-62 |
1 | J:179356 Hu H, Li J, Gagen CS, Gray NW, Zhang Z, Qi Y, Zhang P, Conditional knockout of protein O-mannosyltransferase 2 reveals tissue-specific roles of O-mannosyl glycosylation in brain development. J Comp Neurol. 2011 May 1;519(7):1320-37 |
1 | J:184432 Ichikawa-Tomikawa N, Ogawa J, Douet V, Xu Z, Kamikubo Y, Sakurai T, Kohsaka S, Chiba H, Hattori N, Yamada Y, Arikawa-Hirasawa E, Laminin alpha1 is essential for mouse cerebellar development. Matrix Biol. 2012 Jan;31(1):17-28 |
1 | J:119297 Kikkawa Y, Miner JH, Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function. Dev Biol. 2006 Aug 1;296(1):265-77 |
1 | J:342326 Kim KH, Oprescu SN, Snyder MM, Kim A, Jia Z, Yue F, Kuang S, PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors. Cell Rep. 2023 Oct 24;42(11):113329 |
1 | J:72381 Klaffky E, Williams R, Yao CC, Ziober B, Kramer R, Sutherland A, Trophoblast-Specific Expression and Function of the Integrin alpha7 Subunit in the Peri-implantation Mouse Embryo. Dev Biol. 2001 Nov 1;239(1):161-75 |
1 | J:32701 Kucherer-Ehret A, Pottgiesser J, Kreutzberg GW, Thoenen H, Edgar D, Developmental loss of laminin from the interstitial extracellular matrix correlates with decreased laminin gene expression. Development. 1990 Dec;110(4):1285-93 |
1 | J:23009 Luckenbill-Edds L, Kaiser CA, Rodgers TR, Powell DD, Localization of the 110 kDa receptor for laminin in brains of embryonic and postnatal mice. Cell Tissue Res. 1995 Feb;279(2):371-7 |
1 | J:341276 Matrongolo MJ, Ho-Nguyen KT, Jain M, Ang PS, Reddy A, Schaper S, Tischfield MA, Loss of Twist1 and balanced retinoic acid signaling from the meninges causes cortical folding in mice. Development. 2023 Sep 15;150(18):dev201381 |
1 | J:40187 Miner JH, Patton BL, Lentz SI, Gilbert DJ, Snider WD, Jenkins NA, Copeland NG, Sanes JR, The laminin alpha chains: expression, developmental transitions, and chromosomal locations of alpha1-5, identification of heterotrimeric laminins 8-11, and cloning of a novel alpha3 isoform. J Cell Biol. 1997 May 5;137(3):685-701 |
1* | J:66122 Miosge N, Quondamatteo F, Klenczar C, Herken R, Nidogen-1. Expression and ultrastructural localization during the onset of mesoderm formation in the early mouse embryo. J Histochem Cytochem. 2000 Feb;48(2):229-38 |
1 | J:30299 Morissette N, Carbonetto S, Laminin alpha 2 chain (M chain) is found within the pathway of avian and murine retinal projections. J Neurosci. 1995 Dec;15(12):8067-82 |
1 | J:99790 Ottolenghi C, Omari S, Garcia-Ortiz JE, Uda M, Crisponi L, Forabosco A, Pilia G, Schlessinger D, Foxl2 is required for commitment to ovary differentiation. Hum Mol Genet. 2005 Jul 15;14(14):2053-62 |
1 | J:63385 Park K, Lee YD, Park HJ, Chun YM, Epithelial differentiation in developing murine eustachian tube and middle ear. Otolaryngol Head Neck Surg. 2000 Jun;122(6):902-7 |
1 | J:44761 Patton BL, Miner JH, Chiu AY, Sanes JR, Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice. J Cell Biol. 1997 Dec 15;139(6):1507-21 |
1* | J:84372 Previtali SC, Nodari A, Taveggia C, Pardini C, Dina G, Villa A, Wrabetz L, Quattrini A, Feltri ML, Expression of laminin receptors in schwann cell differentiation: evidence for distinct roles. J Neurosci. 2003 Jul 2;23(13):5520-30 |
1 | J:42107 Qin P, Piechocki M, Lu S, Kurpakus MA, Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye. Dev Dyn. 1997 Aug;209(4):367-76 |
1 | J:150125 Radakovits R, Barros CS, Belvindrah R, Patton B, Muller U, Regulation of radial glial survival by signals from the meninges. J Neurosci. 2009 Jun 17;29(24):7694-705 |
1* | J:255305 Ramirez-Martinez A, Cenik BK, Bezprozvannaya S, Chen B, Bassel-Duby R, Liu N, Olson EN, KLHL41 stabilizes skeletal muscle sarcomeres by nonproteolytic ubiquitination. Elife. 2017 Aug 9;6:e26439 |
1 | J:290205 Richardson N, Gillot I, Gregoire EP, Youssef SA, de Rooij D, de Bruin A, De Cian MC, Chaboissier MC, Sox8 and Sox9 act redundantly for ovarian-to-testicular fate reprogramming in the absence of R-spondin1 in mouse sex reversals. Elife. 2020 May 26;9:e53972 |
1 | J:156199 Robel S, Mori T, Zoubaa S, Schlegel J, Sirko S, Faissner A, Goebbels S, Dimou L, Gotz M, Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis. Glia. 2009 Nov 15;57(15):1630-47 |
1 | J:297217 Roulis M, Kaklamanos A, Schernthanner M, Bielecki P, Zhao J, Kaffe E, Frommelt LS, Qu R, Knapp MS, Henriques A, Chalkidi N, Koliaraki V, Jiao J, Brewer JR, Bacher M, Blackburn HN, Zhao X, Breyer RM, Aidinis V, Jain D, Su B, Herschman HR, Kluger Y, Kollias G, Flavell RA, Paracrine orchestration of intestinal tumorigenesis by a mesenchymal niche. Nature. 2020 Apr;580(7804):524-529 |
1 | J:49695 Sahlberg C, Hormia M, Airenne T, Thesleff I, Laminin gamma2 expression is developmentally regulated during murine tooth morphogenesis and is intense in ameloblasts. J Dent Res. 1998 Aug;77(8):1589-96 |
1 | J:76501 Sasaki T, Giltay R, Talts U, Timpl R, Talts JF, Expression and distribution of laminin alpha1 and alpha2 chains in embryonic and adult mouse tissues: an immunochemical approach. Exp Cell Res. 2002 May 1;275(2):185-99 |
1* | J:30170 Schuler F, Sorokin LM, Expression of laminin isoforms in mouse myogenic cells in vitro and in vivo. J Cell Sci. 1995 Dec;108(Pt 12):3795-805 |
1 | J:241448 Shin JY, Mendez-Lopez I, Hong M, Wang Y, Tanji K, Wu W, Shugol L, Krauss RS, Dauer WT, Worman HJ, Lamina-associated polypeptide 1 is dispensable for embryonic myogenesis but required for postnatal skeletal muscle growth. Hum Mol Genet. 2017 Jan 01;26(1):65-78 |
1 | J:69804 Sixt M, Engelhardt B, Pausch F, Hallmann R, Wendler O, Sorokin LM, Endothelial cell laminin isoforms, laminins 8 and 10, play decisive roles in T cell recruitment across the blood-brain barrier in experimental autoimmune encephalomyelitis. J Cell Biol. 2001 May 28;153(5):933-46 |
1 | J:44408 Sorokin LM, Pausch F, Durbeej M, Ekblom P, Differential expression of five laminin alpha (1-5) chains in developing and adult mouse kidney. Dev Dyn. 1997 Dec;210(4):446-62 |
1 | J:43178 Sorokin LM, Pausch F, Frieser M, Kroger S, Ohage E, Deutzmann R, Developmental regulation of the laminin alpha5 chain suggests a role in epithelial and endothelial cell maturation. Dev Biol. 1997 Sep 15;189(2):285-300 |
1 | J:334330 Thomson E, Tran M, Robevska G, Ayers K, van der Bergen J, Gopalakrishnan Bhaskaran P, Haan E, Cereghini S, Vash-Margita A, Margetts M, Hensley A, Nguyen Q, Sinclair A, Koopman P, Pelosi E, Functional genomics analysis identifies loss of HNF1B function as a cause of Mayer-Rokitansky-Kuster-Hauser syndrome. Hum Mol Genet. 2023 Mar 6;32(6):1032-1047 |
1 | J:44989 Tiger CF, Gullberg D, Abscence of laminin alpha1 chain in the skeletal muscle of dystrophic dy/dy mice. Muscle Nerve. 1997 Dec;20(12):1515-24 |
1 | J:236947 Wallingford MC, Gammill HS, Giachelli CM, Slc20a2 deficiency results in fetal growth restriction and placental calcification associated with thickened basement membranes and novel CD13 and lamininalpha1 expressing cells. Reprod Biol. 2016 Mar;16(1):13-26 |
1 | J:76368 Willem M, Miosge N, Halfter W, Smyth N, Jannetti I, Burghart E, Timpl R, Mayer U, Specific ablation of the nidogen-binding site in the laminin gamma1 chain interferes with kidney and lung development. Development. 2002 Jun;129(11):2711-22 |
1 | J:178649 Yang DH, McKee KK, Chen ZL, Mernaugh G, Strickland S, Zent R, Yurchenco PD, Renal collecting system growth and function depend upon embryonic gamma1 laminin expression. Development. 2011 Oct;138(20):4535-44 |
1 | J:47224 Yoshiba N, Yoshiba K, Aberdam D, Meneguzzi G, Perrin-Schmitt F, Stoetzel C, Ruch JV, Lesot H, Expression and localization of laminin-5 subunits in the mouse incisor. Cell Tissue Res. 1998 Apr;292(1):143-9 |
1* | J:165548 Yoshida T, Miyoshi J, Takai Y, Thesleff I, Cooperation of nectin-1 and nectin-3 is required for normal ameloblast function and crown shape development in mouse teeth. Dev Dyn. 2010 Oct;239(10):2558-69 |
1 | J:22991 Zhang HY, Chu ML, Pan TC, Sasaki T, Timpl R, Ekblom P, Extracellular matrix protein fibulin-2 is expressed in the embryonic endocardial cushion tissue and is a prominent component of valves in adult heart. Dev Biol. 1995 Jan;167(1):18-26 |
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/02/2024 MGI 6.24 |
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