Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AANAT
  • Mouse genes Aanat
  • Rat genes Aanat
  • Zfish genes aanat1,aanat2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aanat

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0071889	14-3-3 protein binding	Aanat	IDA		Rat	PMID:11427721|RGD:8553854
Molecular Function	GO:0016407	acetyltransferase activity	aanat1	IDA		Zfish	PMID:16427617
Molecular Function	GO:0016407	acetyltransferase activity	aanat2	IDA		Zfish	PMID:16427617
Molecular Function	GO:0016407	acetyltransferase activity	aanat2	IDA		Zfish	PMID:10499549
Molecular Function	GO:0004059	aralkylamine N-acetyltransferase activity	AANAT	IDA		Human	PMID:11313340
Molecular Function	GO:0004059	aralkylamine N-acetyltransferase activity	Aanat	IDA		Rat	PMID:10451024|RGD:2301041
Molecular Function	GO:0004060	arylamine N-acetyltransferase activity	Aanat	IDA		Mouse	PMID:7545952
Molecular Function	GO:0005515	protein binding	AANAT	IPI	UniProtKB:O14503	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AANAT	IPI	UniProtKB:Q99750	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AANAT	IPI	UniProtKB:O14503	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	AANAT	IPI	UniProtKB:Q99750	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	AANAT	IPI	UniProtKB:Q13322-4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AANAT	IPI	UniProtKB:Q8IUC2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AANAT	IPI	UniProtKB:Q8N5X7-2	Human	PMID:32296183
Cellular Component	GO:0005737	cytoplasm	Aanat	IDA		Rat	PMID:17198543|RGD:2301034
Cellular Component	GO:0005829	cytosol	AANAT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	AANAT	IDA		Human	PMID:11313340
Biological Process	GO:0071320	cellular response to cAMP	AANAT	IDA		Human	PMID:11313340
Biological Process	GO:0007623	circadian rhythm	AANAT	IMP		Human	PMID:12736803
Biological Process	GO:0007623	circadian rhythm	Aanat	IEP		Rat	PMID:16166080|RGD:2312676
Biological Process	GO:0007623	circadian rhythm	Aanat	IEP		Rat	PMID:18321474|RGD:2301031
Biological Process	GO:0007623	circadian rhythm	aanat2	IGI	ZFIN:ZDB-MRPHLNO-050119-4,ZFIN:ZDB-MRPHLNO-050420-2,ZFIN:ZDB-MRPHLNO-050420-3,ZFIN:ZDB-MRPHLNO-050420-4,ZFIN:ZDB-MRPHLNO-050420-5	Zfish	PMID:15657039
Biological Process	GO:0007623	circadian rhythm	aanat2	IDA		Zfish	PMID:15657039
Biological Process	GO:0007623	circadian rhythm	aanat2	IDA		Zfish	PMID:16497800
Biological Process	GO:0030187	melatonin biosynthetic process	AANAT	IDA		Human	PMID:11313340
Biological Process	GO:0006474	N-terminal protein amino acid acetylation	AANAT	IDA		Human	PMID:11313340
Biological Process	GO:0030593	neutrophil chemotaxis	aanat2	IMP	ZFIN:ZDB-GENO-180320-3	Zfish	PMID:28680128
Biological Process	GO:0009648	photoperiodism	Aanat	IDA		Rat	PMID:12358739|RGD:628397
Biological Process	GO:0009648	photoperiodism	aanat2	IEP		Zfish	PMID:12622837
Biological Process	GO:0045938	positive regulation of circadian sleep/wake cycle, sleep	aanat2	IMP	ZFIN:ZDB-GENO-131125-8	Zfish	PMID:25754820
Biological Process	GO:0051592	response to calcium ion	Aanat	IEP		Rat	PMID:16282194|RGD:2301038
Biological Process	GO:0051591	response to cAMP	Aanat	IEP		Rat	PMID:16024134|RGD:2301039
Biological Process	GO:0046688	response to copper ion	Aanat	IDA		Rat	PMID:10451024|RGD:2301041
Biological Process	GO:0051412	response to corticosterone	Aanat	IEP		Rat	PMID:17014691|RGD:2301035
Biological Process	GO:0034097	response to cytokine	Aanat	IEP		Rat	PMID:17014691|RGD:2301035
Biological Process	GO:0032868	response to insulin	Aanat	IDA		Rat	PMID:18048060|RGD:2301032
Biological Process	GO:0009416	response to light stimulus	Aanat	IEP		Rat	PMID:18001324|RGD:2301033
Biological Process	GO:0009416	response to light stimulus	aanat2	IDA		Zfish	PMID:16537499
Biological Process	GO:0009416	response to light stimulus	aanat2	IGI	ZFIN:ZDB-MRPHLNO-050119-4,ZFIN:ZDB-MRPHLNO-050420-2,ZFIN:ZDB-MRPHLNO-050420-3,ZFIN:ZDB-MRPHLNO-050420-4,ZFIN:ZDB-MRPHLNO-050420-5	Zfish	PMID:15657039
Biological Process	GO:0009416	response to light stimulus	aanat2	IDA		Zfish	PMID:15657039
Biological Process	GO:0009416	response to light stimulus	aanat2	IDA		Zfish	PMID:16497800
Biological Process	GO:0014070	response to organic cyclic compound	Aanat	IDA		Rat	PMID:16805813|RGD:2301036
Biological Process	GO:1901652	response to peptide	Aanat	IEP		Rat	PMID:16166080|RGD:2312676
Biological Process	GO:0034695	response to prostaglandin E	Aanat	IDA		Rat	PMID:6268470|RGD:2301043
Biological Process	GO:0010043	response to zinc ion	Aanat	IDA		Rat	PMID:10451024|RGD:2301041

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern