Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes AATF
  • Mouse genes Aatf
  • Rat genes Aatf
  • Zfish genes aatf
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Aatf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043522	leucine zipper domain binding	AATF	IPI	UniProtKB:O43293	Human	PMID:10580117
Molecular Function	GO:0043522	leucine zipper domain binding	AATF	IPI	UniProtKB:Q96IZ0	Human	PMID:14627703
Molecular Function	GO:0043522	leucine zipper domain binding	Aatf	IPI	RGD:1306551	Rat	PMID:17552904|RGD:2302153
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:P06400	Human	PMID:10783144
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:P52435	Human	PMID:10783144
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:P08047	Human	PMID:12847090
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:O96017	Human	PMID:17157788
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:Q04206	Human	PMID:17157788
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:Q13315	Human	PMID:17157788
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:Q6ZWQ9	Human	PMID:22909821
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:Q8NEJ9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:O75478	Human	PMID:29232376
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:O75528	Human	PMID:29232376
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:Q86TJ2	Human	PMID:29232376
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:Q92830	Human	PMID:29232376
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:Q8NEJ9	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:Q8NEH6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:P27986-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	AATF	IPI	UniProtKB:P63000	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Aatf	IPI	PR:Q9QYH6	Mouse	PMID:17488777
Molecular Function	GO:0005515	protein binding	Aatf	IPI	PR:Q925B0	Mouse	PMID:14627703
Molecular Function	GO:0019901	protein kinase binding	Aatf	IPI	RGD:621766	Rat	PMID:10580117|RGD:631947
Molecular Function	GO:0003723	RNA binding	AATF	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	AATF	HDA		Human	PMID:22681889
Molecular Function	GO:0048156	tau protein binding	Aatf	IPI	RGD:69329	Rat	PMID:14697667|RGD:2300214
Cellular Component	GO:0005737	cytoplasm	AATF	IDA		Human	PMID:14627703
Cellular Component	GO:0005737	cytoplasm	AATF	IDA		Human	PMID:15207272
Cellular Component	GO:0005737	cytoplasm	Aatf	IDA		Mouse	PMID:14627703
Cellular Component	GO:0005737	cytoplasm	Aatf	IDA		Rat	PMID:14697667|RGD:2300214
Cellular Component	GO:0005794	Golgi apparatus	Aatf	IDA		Rat	PMID:14697667|RGD:2300214
Cellular Component	GO:0005730	nucleolus	AATF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	Aatf	IDA		Mouse	PMID:11071758
Cellular Component	GO:0005654	nucleoplasm	AATF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	AATF	IDA		Human	PMID:10580117
Cellular Component	GO:0005634	nucleus	AATF	IDA		Human	PMID:12429849
Cellular Component	GO:0005634	nucleus	AATF	IDA		Human	PMID:14627703
Cellular Component	GO:0005634	nucleus	AATF	IDA		Human	PMID:15207272
Cellular Component	GO:0005634	nucleus	Aatf	IDA		Mouse	PMID:14627703
Cellular Component	GO:0005634	nucleus	Aatf	IDA		Mouse	PMID:11071758
Cellular Component	GO:0005634	nucleus	Aatf	IDA		Rat	PMID:14697667|RGD:2300214
Cellular Component	GO:0005667	transcription regulator complex	Aatf	IDA		Mouse	PMID:19911006
Biological Process	GO:0007155	cell adhesion	Aatf	IMP	MGI:MGI:2176283	Mouse	PMID:11071758
Biological Process	GO:0006974	DNA damage response	AATF	IEP		Human	PMID:18049476
Biological Process	GO:0040016	embryonic cleavage	Aatf	IMP	MGI:MGI:2176283	Mouse	PMID:11071758
Biological Process	GO:0042985	negative regulation of amyloid precursor protein biosynthetic process	Aatf	IDA		Mouse	PMID:14627703
Biological Process	GO:0043066	negative regulation of apoptotic process	AATF	IMP		Human	PMID:15207272
Biological Process	GO:0043066	negative regulation of apoptotic process	Aatf	IDA		Rat	PMID:10580117|RGD:631947
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	Aatf	IGI	MGI:MGI:1930187	Mouse	PMID:17488777
Biological Process	GO:2000378	negative regulation of reactive oxygen species metabolic process	AATF	IDA		Human	PMID:15207272
Biological Process	GO:0032929	negative regulation of superoxide anion generation	AATF	IDA		Human	PMID:15207272
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Aatf	IDA		Rat	PMID:10580117|RGD:631947
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	AATF	IDA		Human	PMID:18049476
Biological Process	GO:0007346	regulation of mitotic cell cycle	Aatf	IMP	MGI:MGI:2176283	Mouse	PMID:11071758
Biological Process	GO:0042254	ribosome biogenesis	Aatf	IMP	MGI:MGI:2176283	Mouse	PMID:11071758

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern