Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ABAT
  • Mouse genes Abat
  • Rat genes Abat
  • Zfish genes abat
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abat

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003867	4-aminobutyrate transaminase activity	ABAT	IDA		Human	PMID:15528998
Molecular Function	GO:0003867	4-aminobutyrate transaminase activity	Abat	IDA		Rat	PMID:10447691|RGD:631980
Molecular Function	GO:0042802	identical protein binding	ABAT	IPI	UniProtKB:P80404	Human	PMID:15528998
Molecular Function	GO:0030170	pyridoxal phosphate binding	ABAT	IDA		Human	PMID:15650327
Cellular Component	GO:0032144	4-aminobutyrate transaminase complex	ABAT	IDA		Human	PMID:15528998
Cellular Component	GO:0005759	mitochondrial matrix	Abat	IDA		Rat	PMID:3132542|RGD:10047077
Cellular Component	GO:0005739	mitochondrion	ABAT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	ABAT	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005739	mitochondrion	Abat	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Abat	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Abat	IDA		Rat	PMID:8835937|RGD:1598523
Cellular Component	GO:0043005	neuron projection	Abat	IDA		Rat	PMID:8247350|RGD:1598528
Biological Process	GO:0007568	aging	Abat	IDA		Rat	PMID:2054153|RGD:10047090
Biological Process	GO:0048148	behavioral response to cocaine	Abat	IMP		Mouse	MGI:MGI:3691518|PMID:10850552
Biological Process	GO:0021549	cerebellum development	Abat	IEP		Rat	PMID:7182074|RGD:10047093
Biological Process	GO:0007620	copulation	Abat	IMP		Rat	PMID:8117236|RGD:1598529
Biological Process	GO:0035640	exploration behavior	Abat	IMP		Rat	PMID:8788866|RGD:10046062
Biological Process	GO:0009449	gamma-aminobutyric acid biosynthetic process	Abat	IMP		Rat	PMID:19540876|RGD:9588538
Biological Process	GO:0009448	gamma-aminobutyric acid metabolic process	ABAT	IDA		Human	PMID:15528998
Biological Process	GO:0007626	locomotory behavior	Abat	IMP		Rat	PMID:7945972|RGD:1598525
Biological Process	GO:0045776	negative regulation of blood pressure	Abat	IMP		Rat	PMID:8336820|RGD:1598530
Biological Process	GO:0033602	negative regulation of dopamine secretion	Abat	IMP		Rat	PMID:590329|RGD:10047092
Biological Process	GO:0014053	negative regulation of gamma-aminobutyric acid secretion	Abat	IMP		Rat	PMID:7722510|RGD:10046061
Biological Process	GO:0090331	negative regulation of platelet aggregation	Abat	IMP		Rat	PMID:12742000|RGD:10047059
Biological Process	GO:1904450	positive regulation of aspartate secretion	Abat	IMP		Rat	PMID:2342602|RGD:10054058
Biological Process	GO:0045964	positive regulation of dopamine metabolic process	Abat	IMP		Rat	PMID:11239920|RGD:10047061
Biological Process	GO:0031652	positive regulation of heat generation	Abat	IMP		Rat	PMID:20878340|RGD:9588531
Biological Process	GO:0097151	positive regulation of inhibitory postsynaptic potential	Abat	IMP		Rat	PMID:11495935|RGD:10047060
Biological Process	GO:0032024	positive regulation of insulin secretion	Abat	IMP		Rat	PMID:20695849|RGD:9588550
Biological Process	GO:1902722	positive regulation of prolactin secretion	Abat	IMP		Rat	PMID:4043235|RGD:10046063
Biological Process	GO:0070474	positive regulation of uterine smooth muscle contraction	Abat	IMP		Rat	PMID:12742000|RGD:10047059
Biological Process	GO:0042220	response to cocaine	Abat	IMP		Rat	PMID:12373739|RGD:1598515
Biological Process	GO:0045471	response to ethanol	Abat	IDA		Rat	PMID:7710740|RGD:1598527
Biological Process	GO:0001666	response to hypoxia	Abat	IMP		Rat	PMID:10727784|RGD:1598521
Biological Process	GO:0010039	response to iron ion	Abat	IDA		Rat	PMID:9719948|RGD:1598519
Biological Process	GO:0035094	response to nicotine	Abat	IMP		Rat	PMID:10025686|RGD:1598517
Biological Process	GO:0009410	response to xenobiotic stimulus	Abat	IDA		Rat	PMID:7931216|RGD:1598526

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern