Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Abcb11

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ABCB11
- Mouse genes Abcb11
- Rat genes Abcb11
- Zfish genes abcb11a,abcb11b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abcb11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015432	ABC-type bile acid transporter activity	ABCB11	IMP		Human	PMID:15791618
Molecular Function	GO:0015432	ABC-type bile acid transporter activity	ABCB11	IMP		Human	PMID:15901796
Molecular Function	GO:0015432	ABC-type bile acid transporter activity	ABCB11	IDA		Human	PMID:18985798
Molecular Function	GO:0015432	ABC-type bile acid transporter activity	ABCB11	IDA		Human	PMID:32203132
Molecular Function	GO:0015432	ABC-type bile acid transporter activity	Abcb11	IMP		Rat	PMID:15901796\|RGD:1598579
Molecular Function	GO:0015432	ABC-type bile acid transporter activity	Abcb11	IDA		Rat	PMID:18985798\|RGD:30309919
Molecular Function	GO:0008559	ABC-type xenobiotic transporter activity	ABCB11	IMP		Human	PMID:18245269
Molecular Function	GO:0008559	ABC-type xenobiotic transporter activity	Abcb11	IMP		Rat	PMID:18245269\|RGD:30309924
Molecular Function	GO:0015125	bile acid transmembrane transporter activity	ABCB11	IMP		Human	PMID:20010382
Molecular Function	GO:0015125	bile acid transmembrane transporter activity	ABCB11	IMP		Human	PMID:20398791
Molecular Function	GO:0015125	bile acid transmembrane transporter activity	ABCB11	IMP		Human	PMID:29507376
Molecular Function	GO:0015125	bile acid transmembrane transporter activity	Abcb11	IMP		Mouse	MGI:MGI:6436413\|PMID:20398791
Molecular Function	GO:0015125	bile acid transmembrane transporter activity	Abcb11	IMP		Rat	PMID:17082223\|RGD:30309920
Molecular Function	GO:0015125	bile acid transmembrane transporter activity	Abcb11	IMP		Rat	PMID:20398791\|RGD:30309945
Molecular Function	GO:0015126	canalicular bile acid transmembrane transporter activity	ABCB11	IMP		Human	PMID:22262466
Molecular Function	GO:0015126	canalicular bile acid transmembrane transporter activity	ABCB11	IMP		Human	PMID:24711118
Molecular Function	GO:0015126	canalicular bile acid transmembrane transporter activity	ABCB11	IDA		Human	PMID:32203132
Molecular Function	GO:0015126	canalicular bile acid transmembrane transporter activity	Abcb11	IMP		Mouse	MGI:MGI:5543985\|PMID:23764895
Molecular Function	GO:0015126	canalicular bile acid transmembrane transporter activity	Abcb11	IDA		Rat	PMID:9545351\|RGD:728120
Molecular Function	GO:0015144	carbohydrate transmembrane transporter activity	Abcb11	IDA		Rat	PMID:15901796\|RGD:1598579
Molecular Function	GO:0005515	protein binding	ABCB11	IPI	UniProtKB:O94973\|UniProtKB:O95782	Human	PMID:22262466
Molecular Function	GO:0005515	protein binding	ABCB11	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Abcb11	IPI	RGD:727960	Rat	PMID:15159385\|RGD:1302732
Molecular Function	GO:0005515	protein binding	Abcb11	IPI	UniProtKB:Q7TSE9	Rat	PMID:15159385\|RGD:1302732
Molecular Function	GO:0005515	protein binding	Abcb11	IPI	UniProtKB:P18484	Rat	PMID:22262466\|RGD:30309927
Cellular Component	GO:0045177	apical part of cell	Abcb11	IDA		Mouse	PMID:15040800
Cellular Component	GO:0016324	apical plasma membrane	ABCB11	IMP		Human	PMID:15791618
Cellular Component	GO:0016324	apical plasma membrane	Abcb11	IDA		Rat	PMID:12370274\|RGD:1598581
Cellular Component	GO:0016324	apical plasma membrane	Abcb11	IDA		Rat	PMID:17082223\|RGD:30309920
Cellular Component	GO:0016324	apical plasma membrane	Abcb11	IDA		Rat	PMID:9545351\|RGD:728120
Cellular Component	GO:0009986	cell surface	ABCB11	IMP		Human	PMID:15791618
Cellular Component	GO:0005768	endosome	Abcb11	IDA		Rat	PMID:11113123\|RGD:30309904
Cellular Component	GO:0070062	extracellular exosome	ABCB11	HDA		Human	PMID:19056867
Cellular Component	GO:0005794	Golgi apparatus	Abcb11	IDA		Rat	PMID:14762791\|RGD:1598570
Cellular Component	GO:0000139	Golgi membrane	Abcb11	IDA		Rat	PMID:10748167\|RGD:1598590
Cellular Component	GO:0046581	intercellular canaliculus	Abcb11	IDA		Mouse	PMID:12068294
Cellular Component	GO:0046581	intercellular canaliculus	Abcb11	IDA		Mouse	PMID:23200860
Cellular Component	GO:0046691	intracellular canaliculus	Abcb11	IDA		Rat	PMID:11113123\|RGD:30309904
Cellular Component	GO:0046691	intracellular canaliculus	Abcb11	IMP		Rat	PMID:15121884\|RGD:30309910
Cellular Component	GO:0046691	intracellular canaliculus	Abcb11	IDA		Rat	PMID:19027009\|RGD:39458026
Cellular Component	GO:0016020	membrane	Abcb11	IDA		Mouse	PMID:11279518
Cellular Component	GO:0005886	plasma membrane	ABCB11	IMP		Human	PMID:20010382
Cellular Component	GO:0005886	plasma membrane	ABCB11	IDA		Human	PMID:22262466
Cellular Component	GO:0005886	plasma membrane	ABCB11	IMP		Human	PMID:24643070
Cellular Component	GO:0005886	plasma membrane	ABCB11	IMP		Human	PMID:29507376
Cellular Component	GO:0005886	plasma membrane	ABCB11	IMP		Human	PMID:30431138
Cellular Component	GO:0005886	plasma membrane	Abcb11	IMP		Mouse	MGI:MGI:5604606\|PMID:24643070
Cellular Component	GO:0005886	plasma membrane	Abcb11	IDA		Rat	PMID:12702498\|RGD:1598571
Cellular Component	GO:0005886	plasma membrane	Abcb11	IDA		Rat	PMID:22262466\|RGD:30309927
Cellular Component	GO:0005886	plasma membrane	Abcb11	IMP		Rat	PMID:24643070\|RGD:30309925
Cellular Component	GO:0055037	recycling endosome	Abcb11	IDA		Rat	PMID:11113123\|RGD:30309904
Cellular Component	GO:0055038	recycling endosome membrane	Abcb11	IMP		Rat	PMID:15121884\|RGD:30309910
Biological Process	GO:0015721	bile acid and bile salt transport	ABCB11	IMP		Human	PMID:15791618
Biological Process	GO:0015721	bile acid and bile salt transport	ABCB11	IMP		Human	PMID:15901796
Biological Process	GO:0015721	bile acid and bile salt transport	ABCB11	IDA		Human	PMID:18985798
Biological Process	GO:0015721	bile acid and bile salt transport	ABCB11	IMP		Human	PMID:19228692
Biological Process	GO:0015721	bile acid and bile salt transport	ABCB11	IMP		Human	PMID:20010382
Biological Process	GO:0015721	bile acid and bile salt transport	ABCB11	IMP		Human	PMID:29507376
Biological Process	GO:0015721	bile acid and bile salt transport	Abcb11	IMP		Mouse	MGI:MGI:3847570\|PMID:19228692
Biological Process	GO:0015721	bile acid and bile salt transport	Abcb11	IMP		Mouse	MGI:MGI:1930837\|PMID:11172067
Biological Process	GO:0015721	bile acid and bile salt transport	Abcb11	IMP		Mouse	MGI:MGI:3512944\|PMID:14570929
Biological Process	GO:0015721	bile acid and bile salt transport	Abcb11	IMP		Rat	PMID:15901796\|RGD:1598579
Biological Process	GO:0015721	bile acid and bile salt transport	Abcb11	IMP		Rat	PMID:16332456\|RGD:14697724
Biological Process	GO:0015721	bile acid and bile salt transport	Abcb11	IMP		Rat	PMID:17082223\|RGD:30309920
Biological Process	GO:0015721	bile acid and bile salt transport	Abcb11	IDA		Rat	PMID:18985798\|RGD:30309919
Biological Process	GO:0015721	bile acid and bile salt transport	Abcb11	IEP		Rat	PMID:27090119\|RGD:15090804
Biological Process	GO:0015721	bile acid and bile salt transport	Abcb11	IEP		Rat	PMID:27939985\|RGD:15036816
Biological Process	GO:0008206	bile acid metabolic process	ABCB11	IMP		Human	PMID:20010382
Biological Process	GO:0008206	bile acid metabolic process	ABCB11	IMP		Human	PMID:29507376
Biological Process	GO:0008206	bile acid metabolic process	ABCB11	IDA		Human	PMID:32203132
Biological Process	GO:0008206	bile acid metabolic process	Abcb11	IDA		Rat	PMID:9545351\|RGD:728120
Biological Process	GO:0032782	bile acid secretion	abcb11b	IMP	ZFIN:ZDB-GENO-181005-1	Zfish	PMID:29091294
Biological Process	GO:0038183	bile acid signaling pathway	Abcb11	IEP		Rat	PMID:27090119\|RGD:15090804
Biological Process	GO:0015722	canalicular bile acid transport	ABCB11	IMP		Human	PMID:20398791
Biological Process	GO:0015722	canalicular bile acid transport	ABCB11	IMP		Human	PMID:22262466
Biological Process	GO:0015722	canalicular bile acid transport	ABCB11	IDA		Human	PMID:32203132
Biological Process	GO:0015722	canalicular bile acid transport	Abcb11	IMP		Mouse	MGI:MGI:6436413\|PMID:20398791
Biological Process	GO:0015722	canalicular bile acid transport	Abcb11	IMP		Mouse	MGI:MGI:5543985\|PMID:23764895
Biological Process	GO:0015722	canalicular bile acid transport	Abcb11	IMP		Mouse	MGI:MGI:5442473\|PMID:22619174
Biological Process	GO:0015722	canalicular bile acid transport	Abcb11	IMP		Mouse	MGI:MGI:1930837\|PMID:11172067
Biological Process	GO:0015722	canalicular bile acid transport	Abcb11	IMP		Rat	PMID:20398791\|RGD:30309945
Biological Process	GO:0015722	canalicular bile acid transport	Abcb11	IDA		Rat	PMID:9545351\|RGD:728120
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Abcb11	IEP		Rat	PMID:27090119\|RGD:15090804
Biological Process	GO:0042632	cholesterol homeostasis	Abcb11	IMP		Mouse	MGI:MGI:1930837\|PMID:11172067
Biological Process	GO:0006631	fatty acid metabolic process	Abcb11	IMP		Mouse	MGI:MGI:5442473\|PMID:22619174
Biological Process	GO:0055088	lipid homeostasis	Abcb11	IMP		Mouse	MGI:MGI:5442473\|PMID:22619174
Biological Process	GO:0055091	phospholipid homeostasis	Abcb11	IMP		Mouse	MGI:MGI:1930837\|PMID:11172067
Biological Process	GO:0120189	positive regulation of bile acid secretion	Abcb11	IMP		Mouse	MGI:MGI:5543985\|PMID:23764895
Biological Process	GO:0120189	positive regulation of bile acid secretion	Abcb11	IMP		Mouse	MGI:MGI:1930837\|PMID:11172067
Biological Process	GO:0016567	protein ubiquitination	ABCB11	IMP		Human	PMID:18829893
Biological Process	GO:0016567	protein ubiquitination	Abcb11	IMP		Rat	PMID:18829893\|RGD:30309917
Biological Process	GO:1904251	regulation of bile acid metabolic process	Abcb11	IMP		Mouse	MGI:MGI:5543985\|PMID:23764895
Biological Process	GO:0120188	regulation of bile acid secretion	Abcb11	IEP		Rat	PMID:27090119\|RGD:15090804
Biological Process	GO:0031998	regulation of fatty acid beta-oxidation	Abcb11	IMP		Mouse	MGI:MGI:5442473\|PMID:22619174
Biological Process	GO:0010468	regulation of gene expression	Abcb11	IEP		Rat	PMID:27090119\|RGD:15090804
Biological Process	GO:0043627	response to estrogen	Abcb11	IEP		Rat	PMID:12702498\|RGD:1598571
Biological Process	GO:0043627	response to estrogen	Abcb11	IEP		Rat	PMID:27090119\|RGD:15090804
Biological Process	GO:0045471	response to ethanol	Abcb11	IEP		Rat	PMID:27939985\|RGD:15036816
Biological Process	GO:0014070	response to organic cyclic compound	Abcb11	IEP		Rat	PMID:27939985\|RGD:15036816
Biological Process	GO:0006979	response to oxidative stress	Abcb11	IEP		Rat	PMID:16452108\|RGD:1598577
Biological Process	GO:0009410	response to xenobiotic stimulus	Abcb11	IMP		Rat	PMID:15901796\|RGD:1598579
Biological Process	GO:0055085	transmembrane transport	Abcb11	IDA		Rat	PMID:15901796\|RGD:1598579
Biological Process	GO:0046618	xenobiotic export from cell	ABCB11	IMP		Human	PMID:18245269
Biological Process	GO:0046618	xenobiotic export from cell	Abcb11	IMP		Rat	PMID:18245269\|RGD:30309924
Biological Process	GO:0006805	xenobiotic metabolic process	ABCB11	IMP		Human	PMID:18245269
Biological Process	GO:0006805	xenobiotic metabolic process	Abcb11	IMP		Rat	PMID:18245269\|RGD:30309924
Biological Process	GO:0006855	xenobiotic transmembrane transport	ABCB11	IMP		Human	PMID:15901796
Biological Process	GO:0006855	xenobiotic transmembrane transport	ABCB11	IMP		Human	PMID:18245269
Biological Process	GO:0006855	xenobiotic transmembrane transport	Abcb11	IMP		Rat	PMID:15901796\|RGD:1598579
Biological Process	GO:0006855	xenobiotic transmembrane transport	Abcb11	IMP		Rat	PMID:18245269\|RGD:30309924

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.