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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Abcb6

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abcb6
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0015439ABC-type heme transporter activityABCB6IMPHumanPMID:17006453
Molecular FunctionGO:0140359ABC-type transporter activityABCB6IMPHumanPMID:23792964
Molecular FunctionGO:0140359ABC-type transporter activityABCB6IDAHumanPMID:27507172
Molecular FunctionGO:0140359ABC-type transporter activityAbcb6IMPMouseMGI:MGI:5424330|PMID:22294697
Molecular FunctionGO:0140359ABC-type transporter activityAbcb6IDAMouseMGI:MGI:5898211|PMID:27507172
Molecular FunctionGO:0005524ATP bindingABCB6IDAHumanPMID:10837493
Molecular FunctionGO:0005524ATP bindingABCB6IDAHumanPMID:27507172
Molecular FunctionGO:0016887ATP hydrolysis activityABCB6IDAHumanPMID:33007128
Molecular FunctionGO:0015562efflux transmembrane transporter activityABCB6IDAHumanPMID:17661442
Molecular FunctionGO:0020037heme bindingABCB6IDAHumanPMID:17006453
Molecular FunctionGO:0020037heme bindingABCB6IDAHumanPMID:33007128
Molecular FunctionGO:0046906tetrapyrrole bindingABCB6IDAHumanPMID:17006453
Molecular FunctionGO:0046906tetrapyrrole bindingABCB6IDAHumanPMID:23792964
Cellular ComponentGO:0005829cytosolABCB6IDAHumanGO_REF:0000052
Cellular ComponentGO:0031901early endosome membraneAbcb6IDARatPMID:18160489|RGD:42722002
Cellular ComponentGO:0036020endolysosome membraneABCB6IDAHumanPMID:25627919
Cellular ComponentGO:0036020endolysosome membraneABCB6IDAHumanPMID:31053883
Cellular ComponentGO:0036020endolysosome membraneAbcb6IDARatPMID:18160489|RGD:42722002
Cellular ComponentGO:0005783endoplasmic reticulumABCB6IDAHumanPMID:22226084
Cellular ComponentGO:0005789endoplasmic reticulum membraneABCB6IDAHumanPMID:21199866
Cellular ComponentGO:0005768endosomeAbcb6IDAMouseMGI:MGI:5546319|PMID:23519333
Cellular ComponentGO:0070062extracellular exosomeABCB6HDAHumanPMID:19056867
Cellular ComponentGO:0070062extracellular exosomeABCB6IDAHumanPMID:22655043
Cellular ComponentGO:0070062extracellular exosomeAbcb6IDAMouseMGI:MGI:6232721|PMID:22655043
Cellular ComponentGO:0005794Golgi apparatusABCB6IDAHumanGO_REF:0000052
Cellular ComponentGO:0005794Golgi apparatusABCB6IDAHumanPMID:18279659
Cellular ComponentGO:0005794Golgi apparatusABCB6IDAHumanPMID:21199866
Cellular ComponentGO:0005794Golgi apparatusABCB6IDAHumanPMID:22226084
Cellular ComponentGO:0031902late endosome membraneAbcb6IDARatPMID:18160489|RGD:42722002
Cellular ComponentGO:0005765lysosomal membraneABCB6IDAHumanPMID:22655043
Cellular ComponentGO:0005765lysosomal membraneABCB6IDAHumanPMID:25627919
Cellular ComponentGO:0005765lysosomal membraneABCB6IDAHumanPMID:29940187
Cellular ComponentGO:0005765lysosomal membraneABCB6IDAHumanPMID:31053883
Cellular ComponentGO:0005765lysosomal membraneAbcb6IDARatPMID:18160489|RGD:42722002
Cellular ComponentGO:0033162melanosome membraneABCB6IDAHumanPMID:29940187
Cellular ComponentGO:0005740mitochondrial envelopeABCB6IDAHumanPMID:10837493
Cellular ComponentGO:0005741mitochondrial outer membraneABCB6IDAHumanPMID:17006453
Cellular ComponentGO:0005741mitochondrial outer membraneABCB6IDAHumanPMID:17661442
Cellular ComponentGO:0005739mitochondrionABCB6IDAHumanGO_REF:0000052
Cellular ComponentGO:0005739mitochondrionABCB6IDAHumanPMID:10837493
Cellular ComponentGO:0005739mitochondrionABCB6IMPHumanPMID:23792964
Cellular ComponentGO:0005739mitochondrionAbcb6HDAMousePMID:18614015
Cellular ComponentGO:0005739mitochondrionAbcb6IDARatPMID:10837493|RGD:1300326
Cellular ComponentGO:0032585multivesicular body membraneABCB6IDAHumanPMID:25627919
Cellular ComponentGO:0005654nucleoplasmABCB6IDAHumanGO_REF:0000052
Cellular ComponentGO:0005886plasma membraneABCB6IDAHumanGO_REF:0000052
Cellular ComponentGO:0005886plasma membraneABCB6IDAHumanPMID:17661442
Cellular ComponentGO:0005886plasma membraneABCB6IDAHumanPMID:22655043
Cellular ComponentGO:0005886plasma membraneABCB6IDAHumanPMID:25627919
Cellular ComponentGO:0005886plasma membraneABCB6IDAHumanPMID:27507172
Biological ProcessGO:0007420brain developmentABCB6IMPHumanPMID:22100072
Biological ProcessGO:0098849cellular detoxification of cadmium ionABCB6IDAHumanPMID:31053883
Biological ProcessGO:0042168heme metabolic processABCB6IDAHumanPMID:33007128
Biological ProcessGO:0035351heme transmembrane transportABCB6IDAHumanPMID:33007128
Biological ProcessGO:0015886heme transportABCB6IMPHumanPMID:17006453
Biological ProcessGO:0015886heme transportABCB6IDAHumanPMID:17661442
Biological ProcessGO:0006878intracellular copper ion homeostasisAbcb6IDARatPMID:18160489|RGD:42722002
Biological ProcessGO:0061072iris morphogenesisabcb6aIMPZFIN:ZDB-MRPHLNO-120216-6ZfishPMID:22226084
Biological ProcessGO:0061072iris morphogenesisabcb6aIMPZFIN:ZDB-MRPHLNO-120216-5ZfishPMID:22226084
Biological ProcessGO:0097325melanocyte proliferationabcb6aIMPZFIN:ZDB-MRPHLNO-140613-1,ZFIN:ZDB-MRPHLNO-140613-2ZfishPMID:24498303
Biological ProcessGO:0097325melanocyte proliferationabcb6aIMPZFIN:ZDB-MRPHLNO-140613-3,ZFIN:ZDB-MRPHLNO-140618-3ZfishPMID:24498303
Biological ProcessGO:1903232melanosome assemblyABCB6IDAHumanPMID:29940187
Biological ProcessGO:0006779porphyrin-containing compound biosynthetic processABCB6IDAHumanPMID:17006453
Biological ProcessGO:0006778porphyrin-containing compound metabolic processABCB6IDAHumanPMID:27507172
Biological ProcessGO:0006778porphyrin-containing compound metabolic processABCB6IMPHumanPMID:33007128
Biological ProcessGO:0006778porphyrin-containing compound metabolic processAbcb6IDAMouseMGI:MGI:5898211|PMID:27507172
Biological ProcessGO:0043588skin developmentABCB6IMPHumanPMID:22100072
Biological ProcessGO:0033013tetrapyrrole metabolic processABCB6IMPHumanPMID:23792964

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory