Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ABCC1
  • Mouse genes Abcc1
  • Rat genes Abcc1
  • Zfish genes abcc1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abcc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015431	ABC-type glutathione S-conjugate transporter activity	Abcc1	IMP		Mouse	MGI:MGI:1099361|PMID:9359705
Molecular Function	GO:0140359	ABC-type transporter activity	ABCC1	IDA		Human	PMID:7961706
Molecular Function	GO:0140359	ABC-type transporter activity	ABCC1	IDA		Human	PMID:9281595
Molecular Function	GO:0015420	ABC-type vitamin B12 transporter activity	ABCC1	EXP		Human	PMID:21511966
Molecular Function	GO:0015420	ABC-type vitamin B12 transporter activity	ABCC1	EXP		Human	PMID:22547309
Molecular Function	GO:0015420	ABC-type vitamin B12 transporter activity	Abcc1	IMP	MGI:MGI:2155908	Mouse	PMID:19897579
Molecular Function	GO:0008559	ABC-type xenobiotic transporter activity	Abcc1	IDA		Rat	PMID:12867490|RGD:2303048
Molecular Function	GO:0008559	ABC-type xenobiotic transporter activity	Abcc1	IMP		Rat	PMID:12893836|RGD:2303061
Molecular Function	GO:0042887	amide transmembrane transporter activity	Abcc1	IDA		Rat	PMID:12423064|RGD:633704
Molecular Function	GO:0034040	ATPase-coupled lipid transmembrane transporter activity	ABCC1	IMP		Human	PMID:17050692
Molecular Function	GO:0034040	ATPase-coupled lipid transmembrane transporter activity	Abcc1	IDA		Rat	PMID:12867490|RGD:2303048
Molecular Function	GO:0046943	carboxylic acid transmembrane transporter activity	ABCC1	IMP		Human	PMID:25986174
Molecular Function	GO:0015562	efflux transmembrane transporter activity	ABCC1	IMP		Human	PMID:25986174
Molecular Function	GO:0015562	efflux transmembrane transporter activity	Abcc1	IMP		Mouse	MGI:MGI:6368305|PMID:26200696
Molecular Function	GO:0015562	efflux transmembrane transporter activity	Abcc1	IDA		Rat	PMID:12423064|RGD:633704
Molecular Function	GO:0034634	glutathione transmembrane transporter activity	Abcc1	IMP		Mouse	MGI:MGI:6368305|PMID:26200696
Molecular Function	GO:0034634	glutathione transmembrane transporter activity	Abcc1	IMP		Rat	PMID:12125073|RGD:2303049
Molecular Function	GO:0005324	long-chain fatty acid transporter activity	Abcc1	IDA		Rat	PMID:12867490|RGD:2303048
Molecular Function	GO:0042910	xenobiotic transmembrane transporter activity	ABCC1	IMP		Human	PMID:25986174
Molecular Function	GO:0042910	xenobiotic transmembrane transporter activity	ABCC1	IDA		Human	PMID:7961706
Molecular Function	GO:0042910	xenobiotic transmembrane transporter activity	ABCC1	IDA		Human	PMID:9281595
Molecular Function	GO:0042910	xenobiotic transmembrane transporter activity	Abcc1	IMP		Mouse	MGI:MGI:6368305|PMID:26200696
Cellular Component	GO:0016324	apical plasma membrane	ABCC1	IDA		Human	PMID:31791063
Cellular Component	GO:0009925	basal plasma membrane	ABCC1	IDA		Human	PMID:18619525
Cellular Component	GO:0009925	basal plasma membrane	Abcc1	IMP	MGI:MGI:2155908	Mouse	PMID:19897579
Cellular Component	GO:0009925	basal plasma membrane	Abcc1	IDA		Rat	PMID:18619525|RGD:2301072
Cellular Component	GO:0016323	basolateral plasma membrane	ABCC1	IDA		Human	PMID:24130369
Cellular Component	GO:0016323	basolateral plasma membrane	ABCC1	IDA		Human	PMID:31791063
Cellular Component	GO:0016323	basolateral plasma membrane	Abcc1	IDA		Rat	PMID:11804835|RGD:2303062
Cellular Component	GO:0016323	basolateral plasma membrane	Abcc1	IDA		Rat	PMID:17854063|RGD:2303043
Cellular Component	GO:0016323	basolateral plasma membrane	Abcc1	IDA		Rat	PMID:18619525|RGD:2301072
Cellular Component	GO:0016323	basolateral plasma membrane	Abcc1	IDA		Rat	PMID:21737571|RGD:25671393
Cellular Component	GO:0016323	basolateral plasma membrane	Abcc1	IDA		Rat	PMID:24130369|RGD:10047278
Cellular Component	GO:0005737	cytoplasm	Abcc1	IDA		Rat	PMID:11804835|RGD:2303062
Cellular Component	GO:0070062	extracellular exosome	ABCC1	HDA		Human	PMID:20458337
Cellular Component	GO:0016328	lateral plasma membrane	ABCC1	IDA		Human	PMID:31791063
Cellular Component	GO:0016020	membrane	ABCC1	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Abcc1	IDA		Rat	PMID:12893836|RGD:2303061
Cellular Component	GO:0005886	plasma membrane	ABCC1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ABCC1	IDA		Human	PMID:17050692
Cellular Component	GO:0005886	plasma membrane	ABCC1	IDA		Human	PMID:23137377
Cellular Component	GO:0005886	plasma membrane	ABCC1	IDA		Human	PMID:28112518
Cellular Component	GO:0005886	plasma membrane	Abcc1	IDA		Mouse	PMID:12951053
Cellular Component	GO:0005886	plasma membrane	Abcc1	IDA		Rat	PMID:11804835|RGD:2303062
Cellular Component	GO:0005886	plasma membrane	Abcc1	IDA		Rat	PMID:17854063|RGD:2303043
Biological Process	GO:1905039	carboxylic acid transmembrane transport	ABCC1	IMP		Human	PMID:25986174
Biological Process	GO:0060326	cell chemotaxis	Abcc1	IMP		Rat	PMID:17050692|RGD:2303045
Biological Process	GO:1904646	cellular response to amyloid-beta	Abcc1	IMP		Mouse	MGI:MGI:6368305|PMID:26200696
Biological Process	GO:0015889	cobalamin transport	Abcc1	IMP	MGI:MGI:2155908	Mouse	PMID:19897579
Biological Process	GO:0070729	cyclic nucleotide transport	ABCC1	IMP		Human	PMID:36070769
Biological Process	GO:0070729	cyclic nucleotide transport	Abcc1	IMP		Mouse	MGI:MGI:7355953|PMID:36070769
Biological Process	GO:0098754	detoxification	abcc1	IMP	ZFIN:ZDB-GENO-170807-5	Zfish	PMID:28282619
Biological Process	GO:0071585	detoxification of cadmium ion	abcc1	IMP	ZFIN:ZDB-GENO-170807-5	Zfish	PMID:28282619
Biological Process	GO:0140115	export across plasma membrane	ABCC1	IMP		Human	PMID:25986174
Biological Process	GO:0140115	export across plasma membrane	Abcc1	IMP		Mouse	MGI:MGI:6368305|PMID:26200696
Biological Process	GO:0140115	export across plasma membrane	Abcc1	IDA		Rat	PMID:15198509|RGD:2303058
Biological Process	GO:0034775	glutathione transmembrane transport	Abcc1	IMP		Rat	PMID:12125073|RGD:2303049
Biological Process	GO:0034775	glutathione transmembrane transport	Abcc1	IMP		Rat	PMID:19053318|RGD:2312652
Biological Process	GO:0071716	leukotriene transport	Abcc1	IMP		Mouse	MGI:MGI:1099361|PMID:9359705
Biological Process	GO:0015911	long-chain fatty acid import across plasma membrane	Abcc1	IDA		Rat	PMID:12867490|RGD:2303048
Biological Process	GO:1901215	negative regulation of neuron death	Abcc1	IMP		Rat	PMID:17141959|RGD:2303044
Biological Process	GO:0033700	phospholipid efflux	Abcc1	IMP		Rat	PMID:17050692|RGD:2303045
Biological Process	GO:0045332	phospholipid translocation	ABCC1	IMP		Human	PMID:17050692
Biological Process	GO:0030335	positive regulation of cell migration	Abcc1	IMP		Rat	PMID:17050692|RGD:2303045
Biological Process	GO:0050729	positive regulation of inflammatory response	Abcc1	IMP		Mouse	MGI:MGI:1099361|PMID:9359705
Biological Process	GO:2001038	regulation of cellular response to drug	Abcc1	IDA		Rat	PMID:15198509|RGD:2303058
Biological Process	GO:0006979	response to oxidative stress	Abcc1	IMP		Rat	PMID:11208926|RGD:631913
Biological Process	GO:0009410	response to xenobiotic stimulus	Abcc1	IMP		Mouse	MGI:MGI:1099361|PMID:9359705
Biological Process	GO:0009410	response to xenobiotic stimulus	Abcc1	IDA		Rat	PMID:14641820|RGD:2303046
Biological Process	GO:0099039	sphingolipid translocation	ABCC1	IMP		Human	PMID:17050692
Biological Process	GO:0070633	transepithelial transport	ABCC1	IMP		Human	PMID:25986174
Biological Process	GO:0055085	transmembrane transport	Abcc1	IDA		Rat	PMID:12423064|RGD:633704
Biological Process	GO:0055085	transmembrane transport	Abcc1	IMP		Rat	PMID:17854063|RGD:2303043
Biological Process	GO:1990961	xenobiotic detoxification by transmembrane export across the plasma membrane	Abcc1	IDA		Rat	PMID:12423064|RGD:633704
Biological Process	GO:0042908	xenobiotic transport	Abcc1	IMP		Mouse	MGI:MGI:6368305|PMID:26200696
Biological Process	GO:0042908	xenobiotic transport	Abcc1	IMP		Rat	PMID:12893836|RGD:2303061
Biological Process	GO:1990962	xenobiotic transport across blood-brain barrier	ABCC1	IMP		Human	PMID:25986174

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern