Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ABCC3
  • Mouse genes Abcc3
  • Rat genes Abcc3
  • Zfish genes abcc3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abcc3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015432	ABC-type bile acid transporter activity	Abcc3	IDA		Rat	PMID:10644759|RGD:40902972
Molecular Function	GO:0015431	ABC-type glutathione S-conjugate transporter activity	ABCC3	IDA		Human	PMID:15083066
Molecular Function	GO:0008559	ABC-type xenobiotic transporter activity	ABCC3	IDA		Human	PMID:11581266
Molecular Function	GO:0008559	ABC-type xenobiotic transporter activity	ABCC3	IMP		Human	PMID:18245269
Molecular Function	GO:0008559	ABC-type xenobiotic transporter activity	ABCC3	IDA		Human	PMID:19334674
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	ABCC3	IDA		Human	PMID:19334674
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	Abcc3	IDA		Rat	PMID:10362653|RGD:8553810
Molecular Function	GO:0015164	glucuronoside transmembrane transporter activity	ABCC3	IDA		Human	PMID:18698235
Molecular Function	GO:0071714	icosanoid transmembrane transporter activity	ABCC3	IDA		Human	PMID:19334674
Molecular Function	GO:0042910	xenobiotic transmembrane transporter activity	ABCC3	IDA		Human	PMID:18698235
Cellular Component	GO:0009925	basal plasma membrane	ABCC3	IDA		Human	PMID:35307651
Cellular Component	GO:0016323	basolateral plasma membrane	ABCC3	IDA		Human	PMID:28408210
Cellular Component	GO:0016323	basolateral plasma membrane	Abcc3	IDA		Mouse	MGI:MGI:3848794|PMID:16225954
Cellular Component	GO:0016323	basolateral plasma membrane	Abcc3	IDA		Rat	PMID:11897632|RGD:724754
Cellular Component	GO:0016323	basolateral plasma membrane	Abcc3	IDA		Rat	PMID:12909565|RGD:1304418
Cellular Component	GO:0005886	plasma membrane	ABCC3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ABCC3	IDA		Human	PMID:18698235
Cellular Component	GO:0005886	plasma membrane	Abcc3	IDA		Mouse	PMID:12951053
Cellular Component	GO:0005886	plasma membrane	Abcc3	IDA		Rat	PMID:18698235|RGD:14929201
Biological Process	GO:0015721	bile acid and bile salt transport	Abcc3	IMP		Rat	PMID:10644759|RGD:40902972
Biological Process	GO:0015722	canalicular bile acid transport	Abcc3	IDA		Rat	PMID:10362653|RGD:8553810
Biological Process	GO:0071716	leukotriene transport	ABCC3	IMP		Human	PMID:11581266
Biological Process	GO:0098656	monoatomic anion transmembrane transport	Abcc3	IDA		Rat	PMID:11837698|RGD:2301070
Biological Process	GO:0032355	response to estradiol	Abcc3	IEP		Rat	PMID:16554369|RGD:2301068
Biological Process	GO:0032496	response to lipopolysaccharide	Abcc3	IEP		Rat	PMID:18505788|RGD:2301058
Biological Process	GO:0014070	response to organic cyclic compound	Abcc3	IEP		Rat	PMID:18648771|RGD:2301056
Biological Process	GO:0010033	response to organic substance	Abcc3	IEP		Rat	PMID:17544377|RGD:2301066
Biological Process	GO:0010243	response to organonitrogen compound	Abcc3	IEP		Rat	PMID:18418891|RGD:2301059
Biological Process	GO:0055085	transmembrane transport	Abcc3	IMP		Rat	PMID:12909565|RGD:1304418
Biological Process	GO:0006855	xenobiotic transmembrane transport	ABCC3	IMP		Human	PMID:11581266
Biological Process	GO:0006855	xenobiotic transmembrane transport	ABCC3	IMP		Human	PMID:18245269
Biological Process	GO:0042908	xenobiotic transport	ABCC3	IDA		Human	PMID:18698235
Biological Process	GO:0042908	xenobiotic transport	ABCC3	IDA		Human	PMID:19334674

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern