Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ABCC5
  • Mouse genes Abcc5
  • Rat genes Abcc5
  • Zfish genes abcc5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abcc5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0140359	ABC-type transporter activity	Abcc5	IMP		Mouse	PMID:17540771
Molecular Function	GO:0008559	ABC-type xenobiotic transporter activity	ABCC5	IMP		Human	PMID:12695538
Molecular Function	GO:0008559	ABC-type xenobiotic transporter activity	ABCC5	IMP		Human	PMID:15899835
Molecular Function	GO:1901505	carbohydrate derivative transmembrane transporter activity	Abcc5	IMP		Mouse	PMID:17540771
Molecular Function	GO:0015562	efflux transmembrane transporter activity	ABCC5	IDA		Human	PMID:10840050
Molecular Function	GO:0034634	glutathione transmembrane transporter activity	ABCC5	IDA		Human	PMID:10840050
Molecular Function	GO:0015232	heme transmembrane transporter activity	ABCC5	IMP		Human	PMID:24836561
Molecular Function	GO:0022884	macromolecule transmembrane transporter activity	Abcc5	IMP		Mouse	PMID:17540771
Molecular Function	GO:0015216	purine nucleotide transmembrane transporter activity	ABCC5	IDA		Human	PMID:10840050
Molecular Function	GO:0042910	xenobiotic transmembrane transporter activity	ABCC5	IDA		Human	PMID:10840050
Cellular Component	GO:0016324	apical plasma membrane	ABCC5	IDA		Human	PMID:15501592
Cellular Component	GO:0016324	apical plasma membrane	ABCC5	IDA		Human	PMID:31791063
Cellular Component	GO:0016324	apical plasma membrane	Abcc5	IDA		Mouse	MGI:MGI:3619890|PMID:16361063
Cellular Component	GO:0016323	basolateral plasma membrane	ABCC5	IDA		Human	PMID:10840050
Cellular Component	GO:0016323	basolateral plasma membrane	ABCC5	IDA		Human	PMID:31791063
Cellular Component	GO:0016323	basolateral plasma membrane	Abcc5	IDA		Mouse	MGI:MGI:5604954|PMID:24836561
Cellular Component	GO:0016323	basolateral plasma membrane	Abcc5	IDA		Rat	PMID:18619525|RGD:2301072
Cellular Component	GO:0016020	membrane	ABCC5	IDA		Human	PMID:15297306
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Abcc5	IDA		Rat	PMID:16997484|RGD:2301088
Cellular Component	GO:0005886	plasma membrane	ABCC5	IDA		Human	PMID:18619525
Cellular Component	GO:0005886	plasma membrane	ABCC5	IDA		Human	PMID:28112518
Cellular Component	GO:0005886	plasma membrane	Abcc5	IMP		Mouse	PMID:17540771
Biological Process	GO:0070730	cAMP transport	ABCC5	IMP		Human	PMID:10893247
Biological Process	GO:0070731	cGMP transport	ABCC5	IMP		Human	PMID:10893247
Biological Process	GO:0030218	erythrocyte differentiation	abcc5	IMP	ZFIN:ZDB-MRPHLNO-150827-2	Zfish	PMID:24836561
Biological Process	GO:0140115	export across plasma membrane	ABCC5	IDA		Human	PMID:10840050
Biological Process	GO:0098838	folate transmembrane transport	ABCC5	IMP		Human	PMID:15899835
Biological Process	GO:0034775	glutathione transmembrane transport	ABCC5	IDA		Human	PMID:10840050
Biological Process	GO:0035351	heme transmembrane transport	ABCC5	IMP		Human	PMID:24836561
Biological Process	GO:0035351	heme transmembrane transport	abcc5	IMP	ZFIN:ZDB-MRPHLNO-150827-2	Zfish	PMID:24836561
Biological Process	GO:0030213	hyaluronan biosynthetic process	Abcc5	IMP		Mouse	PMID:17540771
Biological Process	GO:0015865	purine nucleotide transport	ABCC5	IDA		Human	PMID:10840050
Biological Process	GO:0032868	response to insulin	Abcc5	IEP		Rat	PMID:17762165|RGD:2301086
Biological Process	GO:0032496	response to lipopolysaccharide	Abcc5	IEP		Rat	PMID:15134348|RGD:2301082
Biological Process	GO:0042908	xenobiotic transport	ABCC5	IDA		Human	PMID:10840050
Biological Process	GO:0042908	xenobiotic transport	ABCC5	IMP		Human	PMID:12695538

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern