Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ABCC9
  • Mouse genes Abcc9
  • Rat genes Abcc9
  • Zfish genes abcc9
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abcc9

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015272	ATP-activated inward rectifier potassium channel activity	abcc9	IMP	ZFIN:ZDB-GENO-190708-5	Zfish	PMID:31575858
Molecular Function	GO:0019829	ATPase-coupled monoatomic cation transmembrane transporter activity	Abcc9	IGI	UniProtKB:P70673	Rat	PMID:28842488|RGD:14995313
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	ABCC9	IDA		Human	PMID:26181369
Molecular Function	GO:1901363	heterocyclic compound binding	Abcc9	IPI	CHEBI:34923	Rat	PMID:23078514|RGD:12792001
Molecular Function	GO:0042802	identical protein binding	Abcc9	IPI	UniProtKB:Q63563-2	Rat	PMID:23253866|RGD:8553851
Molecular Function	GO:0005261	monoatomic cation channel activity	Abcc9	IMP		Rat	PMID:26621776|RGD:14929202
Molecular Function	GO:0005267	potassium channel activity	ABCC9	IMP		Human	PMID:24439875
Molecular Function	GO:0005267	potassium channel activity	ABCC9	IMP		Human	PMID:26181369
Molecular Function	GO:0005267	potassium channel activity	Abcc9	IMP	MGI:MGI:2155916	Mouse	PMID:20656890
Molecular Function	GO:0015459	potassium channel regulator activity	Abcc9	IDA		Rat	PMID:8630239|RGD:8554593
Molecular Function	GO:0005515	protein binding	Abcc9	IPI	RGD:621869	Rat	PMID:19491242|RGD:9850103
Molecular Function	GO:0008281	sulfonylurea receptor activity	Abcc9	IDA		Rat	PMID:8630239|RGD:8554593
Molecular Function	GO:0019905	syntaxin binding	Abcc9	IPI	RGD:69430	Rat	PMID:15339904|RGD:1598641
Molecular Function	GO:0022857	transmembrane transporter activity	Abcc9	IMP		Rat	PMID:26621776|RGD:14929202
Molecular Function	GO:0044325	transmembrane transporter binding	ABCC9	IPI	UniProtKB:Q14654	Human	PMID:20610380
Cellular Component	GO:0001669	acrosomal vesicle	Abcc9	IDA		Rat	PMID:21328565|RGD:12792002
Cellular Component	GO:0008282	inward rectifying potassium channel	ABCC9	IDA		Human	PMID:20610380
Cellular Component	GO:0008282	inward rectifying potassium channel	Abcc9	IDA		Rat	PMID:8630239|RGD:8554593
Cellular Component	GO:0005739	mitochondrion	Abcc9	IDA		Rat	PMID:16050978|RGD:1598643
Cellular Component	GO:0005886	plasma membrane	Abcc9	IDA		Mouse	PMID:16085792
Cellular Component	GO:0005886	plasma membrane	Abcc9	IDA		Rat	PMID:14672537|RGD:1598642
Cellular Component	GO:0030017	sarcomere	Abcc9	IDA		Mouse	PMID:16085792
Cellular Component	GO:0030315	T-tubule	Abcc9	IDA		Rat	PMID:15647111|RGD:1598637
Biological Process	GO:0061337	cardiac conduction	ABCC9	IMP		Human	PMID:24439875
Biological Process	GO:0086003	cardiac muscle cell contraction	Abcc9	IMP	MGI:MGI:6389242	Mouse	PMID:31575858
Biological Process	GO:0051607	defense response to virus	ABCC9	IMP		Human	PMID:18026101
Biological Process	GO:0098662	inorganic cation transmembrane transport	Abcc9	IGI	UniProtKB:P70673	Rat	PMID:28842488|RGD:14995313
Biological Process	GO:0098655	monoatomic cation transmembrane transport	Abcc9	IMP		Rat	PMID:26621776|RGD:14929202
Biological Process	GO:0045776	negative regulation of blood pressure	Abcc9	IMP	MGI:MGI:6389242	Mouse	PMID:31575858
Biological Process	GO:1990573	potassium ion import across plasma membrane	Abcc9	IDA		Rat	PMID:8630239|RGD:8554593
Biological Process	GO:0071805	potassium ion transmembrane transport	ABCC9	IMP		Human	PMID:24439875
Biological Process	GO:0071805	potassium ion transmembrane transport	Abcc9	IDA		Rat	PMID:10347249|RGD:1598651
Biological Process	GO:0006813	potassium ion transport	Abcc9	IDA		Rat	PMID:11567030|RGD:70578
Biological Process	GO:0008016	regulation of heart contraction	abcc9	IMP	ZFIN:ZDB-GENO-190708-5	Zfish	PMID:31575858
Biological Process	GO:1903760	regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization	Abcc9	IMP	MGI:MGI:6389242	Mouse	PMID:31575858
Biological Process	GO:0033198	response to ATP	ABCC9	IMP		Human	PMID:24439875
Biological Process	GO:0033198	response to ATP	Abcc9	IGI	UniProtKB:P70673	Rat	PMID:26621776|RGD:14929202
Biological Process	GO:0033198	response to ATP	Abcc9	IGI	UniProtKB:P70673	Rat	PMID:28842488|RGD:14995313
Biological Process	GO:0009410	response to xenobiotic stimulus	Abcc9	IEP		Rat	PMID:15964031|RGD:1598644

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern