Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Abcd1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ABCD1
- Mouse genes Abcd1
- Rat genes Abcd1
- Zfish genes abcd1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abcd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015607	ABC-type fatty-acyl-CoA transporter activity	ABCD1	IDA		Human	PMID:15682271
Molecular Function	GO:0015607	ABC-type fatty-acyl-CoA transporter activity	ABCD1	IGI	UniProtKB:P34230,UniProtKB:P41909	Human	PMID:18757502
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	ABCD1	IDA		Human	PMID:29397936
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	ABCD1	IDA		Human	PMID:33500543
Molecular Function	GO:0043531	ADP binding	ABCD1	IDA		Human	PMID:16946495
Molecular Function	GO:0005524	ATP binding	ABCD1	IDA		Human	PMID:11248239
Molecular Function	GO:0005524	ATP binding	ABCD1	IDA		Human	PMID:16946495
Molecular Function	GO:0005524	ATP binding	Abcd1	IDA		Rat	PMID:12176987\|RGD:1598654
Molecular Function	GO:0005524	ATP binding	Abcd1	IDA		Rat	PMID:8900413\|RGD:1598653
Molecular Function	GO:0016887	ATP hydrolysis activity	ABCD1	IDA		Human	PMID:11248239
Molecular Function	GO:0016887	ATP hydrolysis activity	ABCD1	IDA		Human	PMID:16946495
Molecular Function	GO:0016887	ATP hydrolysis activity	ABCD1	IDA		Human	PMID:33500543
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	ABCD1	IDA		Human	PMID:29397936
Molecular Function	GO:0019899	enzyme binding	ABCD1	IPI	UniProtKB:O14975	Human	PMID:16781659
Molecular Function	GO:0042802	identical protein binding	ABCD1	IPI	UniProtKB:P33897	Human	PMID:10551832
Molecular Function	GO:0005324	long-chain fatty acid transporter activity	ABCD1	EXP		Human	PMID:11500517
Molecular Function	GO:0005324	long-chain fatty acid transporter activity	ABCD1	IGI	UniProtKB:P34230\|UniProtKB:P41909	Human	PMID:18757502
Molecular Function	GO:0005515	protein binding	ABCD1	IPI	UniProtKB:P28288	Human	PMID:10551832
Molecular Function	GO:0005515	protein binding	ABCD1	IPI	UniProtKB:P48410	Human	PMID:10551832
Molecular Function	GO:0005515	protein binding	ABCD1	IPI	UniProtKB:P40855	Human	PMID:10777694
Molecular Function	GO:0005515	protein binding	ABCD1	IPI	UniProtKB:P40855-1	Human	PMID:11883941
Molecular Function	GO:0005515	protein binding	ABCD1	IPI	UniProtKB:P40855-2	Human	PMID:11883941
Molecular Function	GO:0005515	protein binding	ABCD1	IPI	UniProtKB:P40855-4	Human	PMID:11883941
Molecular Function	GO:0005515	protein binding	ABCD1	IPI	UniProtKB:P28288	Human	PMID:17609205
Molecular Function	GO:0005515	protein binding	ABCD1	IPI	UniProtKB:Q9UBJ2	Human	PMID:17609205
Molecular Function	GO:0005515	protein binding	ABCD1	IPI	UniProtKB:P40855	Human	PMID:20531392
Molecular Function	GO:0005515	protein binding	Abcd1	IPI	UniProtKB:Q61285	Mouse	MGI:MGI:6162412\|PMID:25043761
Molecular Function	GO:0005515	protein binding	Abcd1	IPI	UniProtKB:P33897	Mouse	MGI:MGI:3687665\|PMID:10551832
Molecular Function	GO:0005515	protein binding	Abcd1	IPI	RGD:2007	Rat	PMID:12176987\|RGD:1598654
Molecular Function	GO:0005515	protein binding	Abcd1	IPI	RGD:71103	Rat	PMID:16781659\|RGD:2312796
Molecular Function	GO:0005515	protein binding	Abcd1	IPI	UniProtKB:Q9QY44	Rat	PMID:21209459\|RGD:127285396
Molecular Function	GO:0005515	protein binding	Abcd1	IPI	UniProtKB:Q9QY44	Rat	PMID:25043761\|RGD:13673760
Molecular Function	GO:0005515	protein binding	Abcd1	IPI	UniProtKB:Q9QY44	Rat	PMID:28258215\|RGD:127285399
Molecular Function	GO:0046982	protein heterodimerization activity	Abcd1	IDA		Rat	PMID:28258215\|RGD:127285399
Molecular Function	GO:0042803	protein homodimerization activity	ABCD1	IDA		Human	PMID:17609205
Molecular Function	GO:0042803	protein homodimerization activity	ABCD1	IDA		Human	PMID:18757502
Molecular Function	GO:0042803	protein homodimerization activity	ABCD1	IDA		Human	PMID:21145416
Molecular Function	GO:0042803	protein homodimerization activity	Abcd1	IDA		Rat	PMID:28258215\|RGD:127285399
Cellular Component	GO:0005737	cytoplasm	ABCD1	IDA		Human	PMID:17761426
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ABCD1	IDA		Human	PMID:16946495
Cellular Component	GO:0005765	lysosomal membrane	ABCD1	IDA		Human	PMID:16946495
Cellular Component	GO:0016020	membrane	ABCD1	HDA		Human	PMID:19946888
Cellular Component	GO:0031966	mitochondrial membrane	ABCD1	IDA		Human	PMID:16946495
Cellular Component	GO:0005739	mitochondrion	Abcd1	HDA		Mouse	PMID:18614015
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ABCD1	IDA		Human	PMID:17761426
Cellular Component	GO:0005778	peroxisomal membrane	ABCD1	IDA		Human	PMID:10640429
Cellular Component	GO:0005778	peroxisomal membrane	ABCD1	IDA		Human	PMID:16946495
Cellular Component	GO:0005778	peroxisomal membrane	ABCD1	IDA		Human	PMID:17609205
Cellular Component	GO:0005778	peroxisomal membrane	ABCD1	IDA		Human	PMID:29397936
Cellular Component	GO:0005778	peroxisomal membrane	Abcd1	IDA		Mouse	MGI:MGI:3693380\|PMID:14561759
Cellular Component	GO:0005778	peroxisomal membrane	Abcd1	IDA		Rat	PMID:8900413\|RGD:1598653
Cellular Component	GO:0005777	peroxisome	ABCD1	IDA		Human	PMID:10777694
Cellular Component	GO:0005777	peroxisome	ABCD1	IDA		Human	PMID:14533738
Cellular Component	GO:0005777	peroxisome	ABCD1	IDA		Human	PMID:17542813
Cellular Component	GO:0005777	peroxisome	ABCD1	IDA		Human	PMID:17761426
Cellular Component	GO:0005777	peroxisome	ABCD1	IDA		Human	PMID:18757502
Cellular Component	GO:0005777	peroxisome	ABCD1	IDA		Human	PMID:20810565
Cellular Component	GO:0005777	peroxisome	ABCD1	IDA		Human	PMID:9425230
Cellular Component	GO:0005777	peroxisome	Abcd1	IDA		Rat	PMID:10640429\|RGD:8554430
Cellular Component	GO:0005777	peroxisome	Abcd1	IDA		Rat	PMID:25043761\|RGD:13673760
Biological Process	GO:0030325	adrenal gland development	abcd1	IMP		Zfish	PMID:28911205\|ZFIN:ZDB-PUB-170916-8
Biological Process	GO:0030325	adrenal gland development	abcd1	IMP	ZFIN:ZDB-GENO-190206-1	Zfish	PMID:28911205
Biological Process	GO:0030301	cholesterol transport	abcd1	IMP	ZFIN:ZDB-MRPHLNO-170407-1	Zfish	PMID:25860611
Biological Process	GO:0006635	fatty acid beta-oxidation	ABCD1	IDA		Human	PMID:17542813
Biological Process	GO:0006635	fatty acid beta-oxidation	ABCD1	IGI	UniProtKB:P34230\|UniProtKB:P41909	Human	PMID:18757502
Biological Process	GO:0006635	fatty acid beta-oxidation	ABCD1	IGI	UniProtKB:P34230\|UniProtKB:P41909	Human	PMID:21145416
Biological Process	GO:0006635	fatty acid beta-oxidation	ABCD1	IMP		Human	PMID:23671276
Biological Process	GO:0006635	fatty acid beta-oxidation	ABCD1	IDA		Human	PMID:9425230
Biological Process	GO:0006635	fatty acid beta-oxidation	Abcd1	IMP		Mouse	MGI:MGI:5315378\|PMID:10196381
Biological Process	GO:0030497	fatty acid elongation	Abcd1	IMP		Mouse	MGI:MGI:6189658\|PMID:26108493
Biological Process	GO:0055089	fatty acid homeostasis	Abcd1	IMP		Mouse	MGI:MGI:1101351\|PMID:9418970
Biological Process	GO:0042758	long-chain fatty acid catabolic process	ABCD1	IGI	UniProtKB:P34230	Human	PMID:18757502
Biological Process	GO:0042758	long-chain fatty acid catabolic process	ABCD1	IMP		Human	PMID:23671276
Biological Process	GO:0015910	long-chain fatty acid import into peroxisome	ABCD1	IGI	UniProtKB:P34230	Human	PMID:18757502
Biological Process	GO:0061744	motor behavior	abcd1	IMP		Zfish	PMID:28911205\|ZFIN:ZDB-PUB-170916-8
Biological Process	GO:0043217	myelin maintenance	Abcd1	IMP		Mouse	MGI:MGI:3513562\|PMID:15489218
Biological Process	GO:0043217	myelin maintenance	Abcd1	IMP		Mouse	MGI:MGI:2176408\|PMID:11875044
Biological Process	GO:1900016	negative regulation of cytokine production involved in inflammatory response	Abcd1	IMP		Mouse	MGI:MGI:3836690\|PMID:18723473
Biological Process	GO:1903427	negative regulation of reactive oxygen species biosynthetic process	Abcd1	IMP		Mouse	MGI:MGI:3836690\|PMID:18723473
Biological Process	GO:1903427	negative regulation of reactive oxygen species biosynthetic process	Abcd1	IMP		Mouse	MGI:MGI:5790173\|PMID:25583114
Biological Process	GO:1903427	negative regulation of reactive oxygen species biosynthetic process	Abcd1	IMP		Mouse	MGI:MGI:5464985\|PMID:22521832
Biological Process	GO:1990535	neuron projection maintenance	Abcd1	IMP		Mouse	MGI:MGI:2176408\|PMID:11875044
Biological Process	GO:1990535	neuron projection maintenance	Abcd1	IMP		Mouse	MGI:MGI:3513562\|PMID:15489218
Biological Process	GO:0014003	oligodendrocyte development	abcd1	IMP		Zfish	PMID:28911205\|ZFIN:ZDB-PUB-170916-8
Biological Process	GO:0014003	oligodendrocyte development	abcd1	IMP	ZFIN:ZDB-GENO-190206-4	Zfish	PMID:28911205
Biological Process	GO:0014003	oligodendrocyte development	abcd1	IMP	ZFIN:ZDB-GENO-190206-5	Zfish	PMID:28911205
Biological Process	GO:0007031	peroxisome organization	ABCD1	IDA		Human	PMID:9425230
Biological Process	GO:0032000	positive regulation of fatty acid beta-oxidation	ABCD1	IMP		Human	PMID:23123468
Biological Process	GO:0032000	positive regulation of fatty acid beta-oxidation	Abcd1	IMP		Mouse	MGI:MGI:3836690\|PMID:18723473
Biological Process	GO:0032000	positive regulation of fatty acid beta-oxidation	Abcd1	IMP		Mouse	MGI:MGI:3835692\|PMID:18854420
Biological Process	GO:0032000	positive regulation of fatty acid beta-oxidation	Abcd1	IMP		Mouse	MGI:MGI:6189665\|PMID:23123468
Biological Process	GO:0031643	positive regulation of myelination	abcd1	IMP		Zfish	PMID:28911205\|ZFIN:ZDB-PUB-170916-8
Biological Process	GO:0031643	positive regulation of myelination	abcd1	IMP	ZFIN:ZDB-GENO-190206-1	Zfish	PMID:28911205
Biological Process	GO:2001280	positive regulation of unsaturated fatty acid biosynthetic process	Abcd1	IMP		Mouse	MGI:MGI:3835692\|PMID:18854420
Biological Process	GO:1900407	regulation of cellular response to oxidative stress	Abcd1	IMP		Mouse	MGI:MGI:3795085\|PMID:18344354
Biological Process	GO:1900407	regulation of cellular response to oxidative stress	Abcd1	IMP		Mouse	MGI:MGI:5790173\|PMID:25583114
Biological Process	GO:0031998	regulation of fatty acid beta-oxidation	Abcd1	IMP		Mouse	MGI:MGI:1101351\|PMID:9418970
Biological Process	GO:0031998	regulation of fatty acid beta-oxidation	Abcd1	IMP		Mouse	MGI:MGI:5635749\|PMID:25255441
Biological Process	GO:0031998	regulation of fatty acid beta-oxidation	Abcd1	IMP		Mouse	MGI:MGI:87573\|PMID:9126326
Biological Process	GO:0031998	regulation of fatty acid beta-oxidation	Abcd1	IMP		Mouse	MGI:MGI:1095802\|PMID:9256488
Biological Process	GO:0051900	regulation of mitochondrial depolarization	Abcd1	IMP		Mouse	MGI:MGI:5790173\|PMID:25583114
Biological Process	GO:0002082	regulation of oxidative phosphorylation	Abcd1	IMP		Mouse	MGI:MGI:5500881\|PMID:23604518
Biological Process	GO:0055092	sterol homeostasis	Abcd1	IMP		Mouse	MGI:MGI:3607443\|PMID:16213491
Biological Process	GO:0036269	swimming behavior	abcd1	IMP		Zfish	PMID:28911205\|ZFIN:ZDB-PUB-170916-8
Biological Process	GO:0036269	swimming behavior	abcd1	IMP	ZFIN:ZDB-GENO-190206-1	Zfish	PMID:33690217
Biological Process	GO:0036269	swimming behavior	abcd1	IMP	ZFIN:ZDB-GENO-190212-2	Zfish	PMID:33690217
Biological Process	GO:0042760	very long-chain fatty acid catabolic process	ABCD1	IGI	UniProtKB:P34230	Human	PMID:18757502
Biological Process	GO:0042760	very long-chain fatty acid catabolic process	ABCD1	IGI	UniProtKB:P41909	Human	PMID:21145416
Biological Process	GO:0042760	very long-chain fatty acid catabolic process	ABCD1	IDA		Human	PMID:9425230
Biological Process	GO:0042760	very long-chain fatty acid catabolic process	Abcd1	IMP		Mouse	MGI:MGI:3836690\|PMID:18723473
Biological Process	GO:0042760	very long-chain fatty acid catabolic process	Abcd1	IMP		Rat	PMID:25043761\|RGD:13673760
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	ABCD1	IDA		Human	PMID:29397936
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	Abcd1	IMP		Mouse	MGI:MGI:3513562\|PMID:15489218
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	abcd1	IMP		Zfish	PMID:28911205\|ZFIN:ZDB-PUB-170916-8
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	abcd1	IMP	ZFIN:ZDB-GENO-190206-2	Zfish	PMID:28911205
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	abcd1	IMP	ZFIN:ZDB-GENO-190206-1	Zfish	PMID:28911205
Biological Process	GO:0036113	very long-chain fatty-acyl-CoA catabolic process	ABCD1	IMP		Human	PMID:23671276

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/09/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.