Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ABCD2
  • Mouse genes Abcd2
  • Rat genes Abcd2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abcd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	ABCD2	IDA		Human	PMID:29397936
Molecular Function	GO:0016887	ATP hydrolysis activity	ABCD2	IDA		Human	PMID:29397936
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	ABCD2	IDA		Human	PMID:16946495
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	ABCD2	IDA		Human	PMID:29397936
Molecular Function	GO:0005515	protein binding	ABCD2	IPI	UniProtKB:P40855	Human	PMID:10704444
Molecular Function	GO:0005515	protein binding	ABCD2	IPI	UniProtKB:P40855	Human	PMID:10777694
Molecular Function	GO:0005515	protein binding	ABCD2	IPI	UniProtKB:P40855-1	Human	PMID:11883941
Molecular Function	GO:0005515	protein binding	ABCD2	IPI	UniProtKB:P40855-2	Human	PMID:11883941
Molecular Function	GO:0005515	protein binding	ABCD2	IPI	UniProtKB:P40855-4	Human	PMID:11883941
Molecular Function	GO:0005515	protein binding	ABCD2	IPI	UniProtKB:P33897	Human	PMID:17609205
Molecular Function	GO:0005515	protein binding	Abcd2	IPI	UniProtKB:P28288	Mouse	MGI:MGI:3687665|PMID:10551832
Molecular Function	GO:0005515	protein binding	Abcd2	IPI	UniProtKB:P48410	Mouse	MGI:MGI:6162412|PMID:25043761
Molecular Function	GO:0005515	protein binding	Abcd2	IPI	UniProtKB:D3ZHR2	Rat	PMID:21209459|RGD:127285396
Molecular Function	GO:0005515	protein binding	Abcd2	IPI	UniProtKB:D3ZHR2	Rat	PMID:25043761|RGD:13673760
Molecular Function	GO:0005515	protein binding	Abcd2	IPI	UniProtKB:D3ZHR2	Rat	PMID:28258215|RGD:127285399
Molecular Function	GO:0046982	protein heterodimerization activity	Abcd2	IDA		Rat	PMID:28258215|RGD:127285399
Molecular Function	GO:0042803	protein homodimerization activity	ABCD2	IDA		Human	PMID:21145416
Molecular Function	GO:0042803	protein homodimerization activity	Abcd2	IDA		Rat	PMID:28258215|RGD:127285399
Cellular Component	GO:0005739	mitochondrion	Abcd2	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005778	peroxisomal membrane	Abcd2	IDA		Rat	PMID:14561759|RGD:1580664
Cellular Component	GO:0005777	peroxisome	ABCD2	IDA		Human	PMID:10196381
Cellular Component	GO:0005777	peroxisome	ABCD2	IDA		Human	PMID:10329405
Cellular Component	GO:0005777	peroxisome	ABCD2	IDA		Human	PMID:21145416
Cellular Component	GO:0005777	peroxisome	Abcd2	IDA		Mouse	MGI:MGI:1346162|PMID:8577752
Cellular Component	GO:0005777	peroxisome	Abcd2	IDA		Rat	PMID:25043761|RGD:13673760
Biological Process	GO:0006635	fatty acid beta-oxidation	ABCD2	IGI	UniProtKB:P41909	Human	PMID:21145416
Biological Process	GO:0006635	fatty acid beta-oxidation	Abcd2	IMP		Mouse	MGI:MGI:5315378|PMID:10196381
Biological Process	GO:0043217	myelin maintenance	Abcd2	IMP		Mouse	MGI:MGI:3513562|PMID:15489218
Biological Process	GO:1900016	negative regulation of cytokine production involved in inflammatory response	Abcd2	IMP		Mouse	MGI:MGI:3836690|PMID:18723473
Biological Process	GO:1903427	negative regulation of reactive oxygen species biosynthetic process	Abcd2	IMP		Mouse	MGI:MGI:3836690|PMID:18723473
Biological Process	GO:1990535	neuron projection maintenance	Abcd2	IMP		Mouse	MGI:MGI:3513562|PMID:15489218
Biological Process	GO:0032000	positive regulation of fatty acid beta-oxidation	ABCD2	IDA		Human	PMID:10196381
Biological Process	GO:0032000	positive regulation of fatty acid beta-oxidation	Abcd2	IMP		Mouse	MGI:MGI:3836690|PMID:18723473
Biological Process	GO:0032000	positive regulation of fatty acid beta-oxidation	Abcd2	IMP		Mouse	MGI:MGI:3835692|PMID:18854420
Biological Process	GO:2001280	positive regulation of unsaturated fatty acid biosynthetic process	Abcd2	IMP		Mouse	MGI:MGI:3835692|PMID:18854420
Biological Process	GO:0009617	response to bacterium	Abcd2	IEP		Mouse	PMID:23012479
Biological Process	GO:0042760	very long-chain fatty acid catabolic process	ABCD2	IGI	UniProtKB:P41909	Human	PMID:21145416
Biological Process	GO:0042760	very long-chain fatty acid catabolic process	Abcd2	IMP		Mouse	MGI:MGI:3836690|PMID:18723473
Biological Process	GO:0042760	very long-chain fatty acid catabolic process	Abcd2	IMP		Rat	PMID:25043761|RGD:13673760
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	ABCD2	IDA		Human	PMID:10196381
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	ABCD2	IDA		Human	PMID:29397936
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	Abcd2	IMP	UniProtKB:D3ZHR2	Rat	PMID:21209459|RGD:127285396

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern