Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ABCG2
  • Mouse genes Abcg3
  • Rat genes Abcg3l1,Abcg3l3
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abcg3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008559	ABC-type xenobiotic transporter activity	ABCG2	IDA		Human	PMID:9861027
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	ABCG2	IMP		Human	PMID:28554189
Molecular Function	GO:0042626	ATPase-coupled transmembrane transporter activity	ABCG2	IMP		Human	PMID:30405239
Molecular Function	GO:0015562	efflux transmembrane transporter activity	ABCG2	IMP		Human	PMID:17145775
Molecular Function	GO:0015562	efflux transmembrane transporter activity	ABCG2	IMP		Human	PMID:19506252
Molecular Function	GO:0042802	identical protein binding	ABCG2	IPI	UniProtKB:Q9UNQ0	Human	PMID:16870176
Molecular Function	GO:0042802	identical protein binding	ABCG2	IPI	UniProtKB:Q9UNQ0	Human	PMID:17098188
Molecular Function	GO:0042802	identical protein binding	ABCG2	IPI	UniProtKB:Q9UNQ0	Human	PMID:19506252
Molecular Function	GO:0042802	identical protein binding	ABCG2	IPI	UniProtKB:Q9UNQ0	Human	PMID:20399185
Molecular Function	GO:0005515	protein binding	ABCG2	IPI	UniProtKB:P11309-2	Human	PMID:18056989
Molecular Function	GO:0005515	protein binding	ABCG2	IPI	UniProtKB:P0CG48	Human	PMID:19909340
Molecular Function	GO:0042803	protein homodimerization activity	ABCG2	IDA		Human	PMID:16870176
Molecular Function	GO:0032217	riboflavin transmembrane transporter activity	ABCG2	IDA		Human	PMID:17145775
Molecular Function	GO:0015143	urate transmembrane transporter activity	ABCG2	IMP		Human	PMID:19506252
Cellular Component	GO:0031526	brush border membrane	ABCG2	IDA		Human	PMID:19506252
Cellular Component	GO:0045121	membrane raft	ABCG2	IDA		Human	PMID:28623970
Cellular Component	GO:0005654	nucleoplasm	ABCG2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ABCG2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	ABCG2	IDA		Human	PMID:18619525
Cellular Component	GO:0005886	plasma membrane	ABCG2	IDA		Human	PMID:23137377
Biological Process	GO:1990748	cellular detoxification	ABCG2	IDA		Human	PMID:9861027
Biological Process	GO:0097744	renal urate salt excretion	ABCG2	IMP		Human	PMID:19506252
Biological Process	GO:0032218	riboflavin transport	ABCG2	IDA		Human	PMID:17145775
Biological Process	GO:0070633	transepithelial transport	ABCG2	IDA		Human	PMID:12958161
Biological Process	GO:0055085	transmembrane transport	ABCG2	IMP		Human	PMID:28554189
Biological Process	GO:0055085	transmembrane transport	ABCG2	IMP		Human	PMID:30405239
Biological Process	GO:0046415	urate metabolic process	ABCG2	IMP		Human	PMID:18834626
Biological Process	GO:0046415	urate metabolic process	ABCG2	IMP		Human	PMID:19503597
Biological Process	GO:0046415	urate metabolic process	ABCG2	IMP		Human	PMID:20053405
Biological Process	GO:1990962	xenobiotic transport across blood-brain barrier	ABCG2	IDA		Human	PMID:12958161

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern