Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ABHD6
  • Mouse genes Abhd6
  • Rat genes Abhd6
  • Zfish genes abhd6a,abhd6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abhd6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047372	acylglycerol lipase activity	ABHD6	IDA		Human	PMID:22969151
Molecular Function	GO:0047372	acylglycerol lipase activity	Abhd6	IDA		Mouse	MGI:MGI:5616317|PMID:18096503
Molecular Function	GO:0047372	acylglycerol lipase activity	Abhd6	IDA		Mouse	MGI:MGI:5700445|PMID:26491015
Molecular Function	GO:0047372	acylglycerol lipase activity	Abhd6	IMP		Mouse	PMID:20657592
Molecular Function	GO:0047372	acylglycerol lipase activity	Abhd6	IDA		Mouse	PMID:20657592
Molecular Function	GO:0004620	phospholipase activity	Abhd6	IDA		Mouse	MGI:MGI:5528738|PMID:24095738
Molecular Function	GO:0005515	protein binding	ABHD6	IPI	UniProtKB:Q5QGT7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ABHD6	IPI	UniProtKB:Q969E2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ABHD6	IPI	UniProtKB:Q9NYZ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ABHD6	IPI	UniProtKB:Q9Y3D6	Human	PMID:32296183
Cellular Component	GO:0032281	AMPA glutamate receptor complex	Abhd6	IDA		Mouse	PMID:22632720
Cellular Component	GO:0098982	GABA-ergic synapse	Abhd6	IDA		Mouse	PMID:20657592
Cellular Component	GO:0098978	glutamatergic synapse	Abhd6	IDA		Mouse	PMID:20657592
Cellular Component	GO:0098978	glutamatergic synapse	Abhd6	EXP		Mouse	PMID:20657592
Cellular Component	GO:0031902	late endosome membrane	Abhd6	IDA		Mouse	MGI:MGI:5700445|PMID:26491015
Cellular Component	GO:0005765	lysosomal membrane	Abhd6	IDA		Mouse	MGI:MGI:5700445|PMID:26491015
Cellular Component	GO:0016020	membrane	Abhd6	IDA		Mouse	MGI:MGI:5616317|PMID:18096503
Cellular Component	GO:0005739	mitochondrion	Abhd6	IDA		Mouse	PMID:20657592
Cellular Component	GO:0045211	postsynaptic membrane	Abhd6	IDA		Mouse	PMID:20657592
Biological Process	GO:0046464	acylglycerol catabolic process	ABHD6	IDA		Human	PMID:22969151
Biological Process	GO:0046464	acylglycerol catabolic process	Abhd6	IDA		Mouse	MGI:MGI:5616317|PMID:18096503
Biological Process	GO:0060292	long-term synaptic depression	Abhd6	IMP		Mouse	PMID:20657592
Biological Process	GO:2001311	lysobisphosphatidic acid metabolic process	Abhd6	IDA		Mouse	MGI:MGI:5700445|PMID:26491015
Biological Process	GO:0052651	monoacylglycerol catabolic process	Abhd6	IDA		Mouse	MGI:MGI:5700445|PMID:26491015
Biological Process	GO:0030336	negative regulation of cell migration	Abhd6	IMP		Mouse	PMID:20657592
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	Abhd6	IMP		Mouse	MGI:MGI:5791035|PMID:26997277
Biological Process	GO:0009395	phospholipid catabolic process	Abhd6	IDA		Mouse	MGI:MGI:5528738|PMID:24095738
Biological Process	GO:0046889	positive regulation of lipid biosynthetic process	Abhd6	IMP		Mouse	MGI:MGI:5528738|PMID:24095738
Biological Process	GO:2000124	regulation of endocannabinoid signaling pathway	Abhd6	IMP		Mouse	PMID:20657592
Biological Process	GO:0099178	regulation of retrograde trans-synaptic signaling by endocanabinoid	Abhd6	IDA		Mouse	PMID:20657592
Biological Process	GO:0099178	regulation of retrograde trans-synaptic signaling by endocanabinoid	Abhd6	EXP		Mouse	PMID:20657592

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern