Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ABI2
  • Mouse genes Abi2
  • Rat genes Abi2
  • Zfish genes abi2a,abi2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abi2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	ABI2	IPI	UniProtKB:Q9NYB9	Human	PMID:25416956
Molecular Function	GO:0042802	identical protein binding	ABI2	IPI	UniProtKB:Q9NYB9	Human	PMID:29892012
Molecular Function	GO:0070064	proline-rich region binding	ABI2	IPI	UniProtKB:P00519	Human	PMID:7590236
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O43639	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P08727	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P18206	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P19012	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P35900	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q15154	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q8IY31	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9Y3C0	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P00519	Human	PMID:17101133
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q8VHK2	Human	PMID:19523119
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q8IYA8	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:B1Q236,UniProtKB:Q7L576,UniProtKB:Q8WUW1,UniProtKB:Q92558,UniProtKB:Q9Y2A7	Human	PMID:24439377
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:A1A4E9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:A7KAX9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O14964	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O43186	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O43281	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O43516	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O43639	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O60941	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O75886	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P19012	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P25791	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P30405	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P37198	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P50552	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P54646	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P61978	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q08117	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q13049	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q13131	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q13526	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q14525	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q15323	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q15654	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q569H4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q5ST30-4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q5T5P2-6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q68D86	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q6IB98	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q8IY31	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q8IYA8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q8TD31-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q96CN9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q96HT8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q96QH2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9BVG8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9H6L4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9H6Z9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9H9J2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9NSC5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9UBB9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9UL45	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:A7KAX9	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O00560	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O14964	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O43186	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O43281	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O43516	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O43639	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O60941	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O75886	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P08727	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P18206	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P19012	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P25791	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P30405	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P35900	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P37198	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P50552	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P54646	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P61978	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q08117	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q13049	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q13131	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q13526	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q15154	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q15323	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q15654	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q569H4	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q68D86	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q8IY31	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q8IYA8	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q8TD31	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q96CN9	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q96HT8	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9BVG8	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9H6L4	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9NSC5	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9UBB9	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9UL45	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9Y3C0	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O43281	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:O60941	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:P37198	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q13049	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9UBB9	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ABI2	IPI	UniProtKB:Q9Y3C0	Human	PMID:31515488
Molecular Function	GO:0017124	SH3 domain binding	ABI2	IPI	UniProtKB:P00519	Human	PMID:7590236
Molecular Function	GO:0035591	signaling adaptor activity	ABI2	IDA		Human	PMID:17101133
Molecular Function	GO:0035591	signaling adaptor activity	ABI2	IDA		Human	PMID:21107423
Molecular Function	GO:0031267	small GTPase binding	ABI2	IDA		Human	PMID:21107423
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ABI2	IPI	UniProtKB:Q13049	Human	PMID:18632609
Cellular Component	GO:0005912	adherens junction	Abi2	IDA		Mouse	PMID:15572692
Cellular Component	GO:0005829	cytosol	ABI2	IDA		Human	PMID:17101133
Cellular Component	GO:0005829	cytosol	ABI2	IDA		Human	PMID:18632609
Cellular Component	GO:0030425	dendrite	Abi2	IDA		Mouse	PMID:15572692
Cellular Component	GO:0043197	dendritic spine	Abi2	IDA		Mouse	MGI:MGI:3525751|PMID:15572692
Cellular Component	GO:0032433	filopodium tip	ABI2	IDA		Human	PMID:11516653
Cellular Component	GO:0098978	glutamatergic synapse	Abi2	IDA		Mouse	PMID:15572692
Cellular Component	GO:0098978	glutamatergic synapse	Abi2	IMP		Mouse	PMID:15572692
Cellular Component	GO:0030027	lamellipodium	ABI2	IDA		Human	PMID:11516653
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	Abi2	IDA		Mouse	PMID:15572692
Cellular Component	GO:0098871	postsynaptic actin cytoskeleton	Abi2	IMP		Mouse	PMID:15572692
Cellular Component	GO:0031209	SCAR complex	ABI2	IDA		Human	PMID:21107423
Biological Process	GO:0043010	camera-type eye development	Abi2	IMP	MGI:MGI:3526871	Mouse	PMID:15572692
Biological Process	GO:0016477	cell migration	Abi2	IMP	MGI:MGI:3526871	Mouse	PMID:15572692
Biological Process	GO:0016358	dendrite development	Abi2	IMP	MGI:MGI:3526871	Mouse	PMID:15572692
Biological Process	GO:0007611	learning or memory	Abi2	IMP	MGI:MGI:3526871	Mouse	PMID:15572692
Biological Process	GO:0070309	lens fiber cell morphogenesis	Abi2	IMP		Mouse	MGI:MGI:3525751|PMID:15572692
Biological Process	GO:0001764	neuron migration	Abi2	IMP	MGI:MGI:3526871	Mouse	PMID:15572692
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	ABI2	IDA		Human	PMID:17101133
Biological Process	GO:2000601	positive regulation of Arp2/3 complex-mediated actin nucleation	ABI2	IDA		Human	PMID:21107423
Biological Process	GO:0010592	positive regulation of lamellipodium assembly	ABI2	IDA		Human	PMID:21107423
Biological Process	GO:0099173	postsynapse organization	Abi2	IMP		Mouse	PMID:15572692
Biological Process	GO:0099173	postsynapse organization	Abi2	IDA		Mouse	PMID:15572692
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Abi2	IDA		Mouse	PMID:15572692
Biological Process	GO:0098974	postsynaptic actin cytoskeleton organization	Abi2	IMP		Mouse	PMID:15572692
Biological Process	GO:0016601	Rac protein signal transduction	ABI2	IDA		Human	PMID:21107423
Biological Process	GO:0061001	regulation of dendritic spine morphogenesis	Abi2	IMP		Mouse	MGI:MGI:3525751|PMID:15572692

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern