Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Abl2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes ABL2
- Mouse genes Abl2
- Rat genes Abl2
- Zfish genes abl2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Abl2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000287	magnesium ion binding	ABL2	IDA		Human	PMID:15886098
Molecular Function	GO:0000287	magnesium ion binding	Abl2	IDA		Mouse	MGI:MGI:3693389\|PMID:12748290
Molecular Function	GO:0030145	manganese ion binding	ABL2	IDA		Human	PMID:15886098
Molecular Function	GO:0030145	manganese ion binding	Abl2	IDA		Mouse	MGI:MGI:3693389\|PMID:12748290
Molecular Function	GO:0001784	phosphotyrosine residue binding	ABL2	IPI	UniProtKB:O84462	Human	PMID:20624904
Molecular Function	GO:0001784	phosphotyrosine residue binding	ABL2	IPI	UniProtKB:Q6GX35	Human	PMID:20624904
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P07203	Human	PMID:12893824
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P46108	Human	PMID:15886098
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:Q13671	Human	PMID:15886098
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P00533	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P04626	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P21860	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:Q15303	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P06241	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P12931	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P19174	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P27986	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P46108	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P62993	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P46108	Human	PMID:19380743
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:Q8IZP0	Human	PMID:20598684
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P00533	Human	PMID:24658140
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P10721	Human	PMID:24728074
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P16333	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:Q15637	Human	PMID:26420826
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P36888	Human	PMID:28086240
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:Q13671	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ABL2	IPI	UniProtKB:P00533	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	Abl2	IPI	PR:Q60598	Mouse	PMID:19414610
Molecular Function	GO:0005515	protein binding	Abl2	IPI	PR:P09055	Mouse	PMID:22357865
Molecular Function	GO:0004713	protein tyrosine kinase activity	ABL2	IDA		Human	PMID:15886098
Molecular Function	GO:0004713	protein tyrosine kinase activity	ABL2	IMP		Human	PMID:22810897
Molecular Function	GO:0004713	protein tyrosine kinase activity	Abl2	IDA		Mouse	MGI:MGI:3693389\|PMID:12748290
Molecular Function	GO:0004713	protein tyrosine kinase activity	Abl2	IDA		Mouse	PMID:18827006
Molecular Function	GO:0004713	protein tyrosine kinase activity	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:20837657
Molecular Function	GO:0004713	protein tyrosine kinase activity	Abl2	IDA		Mouse	PMID:15084284
Molecular Function	GO:0004713	protein tyrosine kinase activity	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:18827006
Molecular Function	GO:0004713	protein tyrosine kinase activity	Abl2	IDA		Mouse	PMID:23100514
Molecular Function	GO:0004713	protein tyrosine kinase activity	Abl2	IMP	MGI:MGI:2153719	Mouse	PMID:15084284
Molecular Function	GO:0004713	protein tyrosine kinase activity	Abl2	IDA		Mouse	PMID:19414610
Cellular Component	GO:0015629	actin cytoskeleton	Abl2	IDA		Mouse	PMID:11752434
Cellular Component	GO:0043197	dendritic spine	Abl2	IDA		Mouse	PMID:23365224
Cellular Component	GO:0098978	glutamatergic synapse	Abl2	IMP		Mouse	PMID:27335408
Cellular Component	GO:0098978	glutamatergic synapse	Abl2	IDA		Mouse	PMID:27335408
Cellular Component	GO:0098978	glutamatergic synapse	Abl2	IDA		Mouse	PMID:23365224
Cellular Component	GO:0098978	glutamatergic synapse	Abl2	IMP		Mouse	PMID:23365224
Cellular Component	GO:0030027	lamellipodium	Abl2	IDA		Mouse	PMID:19414610
Cellular Component	GO:0001891	phagocytic cup	Abl2	IDA		Mouse	PMID:23100514
Cellular Component	GO:0098794	postsynapse	Abl2	IMP		Mouse	PMID:23365224
Cellular Component	GO:0098794	postsynapse	Abl2	IDA		Mouse	PMID:23365224
Biological Process	GO:0030036	actin cytoskeleton organization	Abl2	IDA		Mouse	MGI:MGI:2155495\|PMID:11752434
Biological Process	GO:0030036	actin cytoskeleton organization	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:9883720
Biological Process	GO:0051017	actin filament bundle assembly	Abl2	IDA		Mouse	PMID:11752434
Biological Process	GO:0007015	actin filament organization	Abl2	IDA		Mouse	PMID:11752434
Biological Process	GO:0007628	adult walking behavior	Abl2	IMP	MGI:MGI:2153719	Mouse	PMID:9883720
Biological Process	GO:0002118	aggressive behavior	Abl2	IMP	MGI:MGI:2153719	Mouse	PMID:9883720
Biological Process	GO:0046632	alpha-beta T cell differentiation	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:18025176
Biological Process	GO:0031223	auditory behavior	Abl2	IMP	MGI:MGI:2153719	Mouse	PMID:9883720
Biological Process	GO:0060020	Bergmann glial cell differentiation	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:20980600
Biological Process	GO:0098609	cell-cell adhesion	Abl2	IGI	MGI:MGI:103178	Mouse	PMID:24367707
Biological Process	GO:0098609	cell-cell adhesion	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:24367707
Biological Process	GO:0071300	cellular response to retinoic acid	ABL2	IMP		Human	PMID:17910947
Biological Process	GO:0021587	cerebellum morphogenesis	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:20980600
Biological Process	GO:0072359	circulatory system development	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:9883720
Biological Process	GO:0048813	dendrite morphogenesis	Abl2	IMP		Mouse	PMID:23365224
Biological Process	GO:0048813	dendrite morphogenesis	Abl2	IGI	MGI:MGI:96610	Mouse	PMID:22357865
Biological Process	GO:0048813	dendrite morphogenesis	Abl2	IGI	MGI:MGI:107926	Mouse	PMID:23365224
Biological Process	GO:0097062	dendritic spine maintenance	Abl2	IGI	MGI:MGI:99695	Mouse	PMID:23365224
Biological Process	GO:0097062	dendritic spine maintenance	Abl2	IMP		Mouse	PMID:23365224
Biological Process	GO:1904157	DN4 thymocyte differentiation	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:18025176
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	Abl2	IGI	MGI:MGI:95294	Mouse	PMID:18827006
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	Abl2	IGI	MGI:MGI:95290	Mouse	PMID:18827006
Biological Process	GO:0051649	establishment of localization in cell	Abl2	IMP	MGI:MGI:2153719	Mouse	PMID:22665498
Biological Process	GO:0051649	establishment of localization in cell	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:23100514
Biological Process	GO:0035640	exploration behavior	Abl2	IGI	MGI:MGI:96602	Mouse	PMID:23595732
Biological Process	GO:0007249	I-kappaB kinase/NF-kappaB signaling	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:18025176
Biological Process	GO:0007612	learning	Abl2	IMP	MGI:MGI:2153719	Mouse	PMID:19805386
Biological Process	GO:0035264	multicellular organism growth	Abl2	IMP	MGI:MGI:2153719	Mouse	PMID:9883720
Biological Process	GO:0022408	negative regulation of cell-cell adhesion	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:24367707
Biological Process	GO:0022408	negative regulation of cell-cell adhesion	Abl2	IGI	MGI:MGI:103178	Mouse	PMID:24367707
Biological Process	GO:2000352	negative regulation of endothelial cell apoptotic process	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:23840065
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	Abl2	IGI	MGI:MGI:1929494	Mouse	PMID:22357865
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	Abl2	IGI	MGI:MGI:1929494	Mouse	PMID:23595732
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	Abl2	IGI	MGI:MGI:1929494	Mouse	PMID:15084284
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	Abl2	IGI	MGI:MGI:96610	Mouse	PMID:22357865
Biological Process	GO:0035024	negative regulation of Rho protein signal transduction	Abl2	IGI	MGI:MGI:96602	Mouse	PMID:23595732
Biological Process	GO:0001843	neural tube closure	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:9883720
Biological Process	GO:0060563	neuroepithelial cell differentiation	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:9883720
Biological Process	GO:0050885	neuromuscular process controlling balance	Abl2	IMP	MGI:MGI:2153719	Mouse	PMID:9883720
Biological Process	GO:0050885	neuromuscular process controlling balance	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:20980600
Biological Process	GO:0030182	neuron differentiation	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:9883720
Biological Process	GO:0016322	neuron remodeling	Abl2	IMP	MGI:MGI:2153719	Mouse	PMID:19805386
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	ABL2	IDA		Human	PMID:15886098
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	Abl2	IDA		Mouse	MGI:MGI:3693389\|PMID:12748290
Biological Process	GO:0006909	phagocytosis	Abl2	IMP	MGI:MGI:2153719	Mouse	PMID:22665498
Biological Process	GO:0006909	phagocytosis	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:23100514
Biological Process	GO:0048008	platelet-derived growth factor receptor signaling pathway	Abl2	IGI	MGI:MGI:99511	Mouse	PMID:18827006
Biological Process	GO:0007204	positive regulation of cytosolic calcium ion concentration	ABL2	IMP		Human	PMID:24367707
Biological Process	GO:0070374	positive regulation of ERK1 and ERK2 cascade	Abl2	IGI	MGI:MGI:99511	Mouse	PMID:18827006
Biological Process	GO:1903905	positive regulation of establishment of T cell polarity	Abl2	IMP		Mouse	MGI:MGI:6142789\|PMID:22810897
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:18025176
Biological Process	GO:0032743	positive regulation of interleukin-2 production	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:18025176
Biological Process	GO:0010976	positive regulation of neuron projection development	ABL2	IMP		Human	PMID:17910947
Biological Process	GO:0010976	positive regulation of neuron projection development	Abl2	IGI	MGI:MGI:1929494	Mouse	PMID:15084284
Biological Process	GO:0051353	positive regulation of oxidoreductase activity	ABL2	IDA		Human	PMID:12893824
Biological Process	GO:0010863	positive regulation of phospholipase C activity	ABL2	IMP		Human	PMID:24367707
Biological Process	GO:0032092	positive regulation of protein binding	Abl2	IMP	MGI:MGI:2153719	Mouse	PMID:15084284
Biological Process	GO:2000406	positive regulation of T cell migration	Abl2	IMP		Mouse	MGI:MGI:6142789\|PMID:22810897
Biological Process	GO:0032729	positive regulation of type II interferon production	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:18025176
Biological Process	GO:2000096	positive regulation of Wnt signaling pathway, planar cell polarity pathway	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:20837657
Biological Process	GO:0009791	post-embryonic development	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:9883720
Biological Process	GO:0008104	protein localization	Abl2	IMP		Mouse	PMID:23365224
Biological Process	GO:0006468	protein phosphorylation	Abl2	IDA		Mouse	MGI:MGI:3693389\|PMID:12748290
Biological Process	GO:1903053	regulation of extracellular matrix organization	Abl2	IGI	MGI:MGI:87859	Mouse	PMID:20980600
Biological Process	GO:0022414	reproductive process	Abl2	IMP	MGI:MGI:2153719	Mouse	PMID:9883720
Biological Process	GO:0007266	Rho protein signal transduction	Abl2	IGI	MGI:MGI:1929494	Mouse	PMID:23595732
Biological Process	GO:0007266	Rho protein signal transduction	Abl2	IGI	MGI:MGI:96602	Mouse	PMID:23595732
Biological Process	GO:0006930	substrate-dependent cell migration, cell extension	Abl2	IGI	MGI:MGI:99695	Mouse	PMID:19414610
Biological Process	GO:0006930	substrate-dependent cell migration, cell extension	Abl2	IGI	MGI:MGI:109601	Mouse	PMID:19414610
Biological Process	GO:0060074	synapse maturation	Abl2	IDA		Mouse	PMID:27335408
Biological Process	GO:0060074	synapse maturation	Abl2	IMP		Mouse	PMID:27335408
Biological Process	GO:0008542	visual learning	Abl2	IGI	MGI:MGI:96610	Mouse	PMID:22357865

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.