Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACADL
  • Mouse genes Acadl
  • Rat genes Acadl
  • Zfish genes acadl
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Acadl

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000062	fatty-acyl-CoA binding	Acadl	IDA		Rat	PMID:3968063|RGD:2317678
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	Acadl	IDA		Rat	PMID:3968063|RGD:2317678
Molecular Function	GO:0042802	identical protein binding	Acadl	IPI	RGD:2011	Rat	PMID:3968063|RGD:2317678
Molecular Function	GO:0004466	long-chain-acyl-CoA dehydrogenase activity	Acadl	IMP		Mouse	MGI:MGI:1321427|PMID:9861014
Molecular Function	GO:0004466	long-chain-acyl-CoA dehydrogenase activity	Acadl	IDA		Rat	PMID:3968063|RGD:2317678
Molecular Function	GO:0016401	palmitoyl-CoA oxidase activity	Acadl	IMP		Mouse	MGI:MGI:1321427|PMID:9861014
Molecular Function	GO:0005515	protein binding	ACADL	IPI	UniProtKB:P22735	Human	PMID:32296183
Cellular Component	GO:0005759	mitochondrial matrix	Acadl	IDA		Rat	PMID:3813556|RGD:8553446
Cellular Component	GO:0031966	mitochondrial membrane	Acadl	IDA		Rat	PMID:3813556|RGD:8553446
Cellular Component	GO:0005739	mitochondrion	Acadl	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005739	mitochondrion	Acadl	IDA		Mouse	PMID:26767982
Cellular Component	GO:0005739	mitochondrion	Acadl	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Acadl	IDA		Rat	PMID:3968063|RGD:2317678
Biological Process	GO:0042413	carnitine catabolic process	Acadl	IMP		Mouse	MGI:MGI:1321427|PMID:9861014
Biological Process	GO:0019254	carnitine metabolic process, CoA-linked	Acadl	IMP		Mouse	MGI:MGI:1321427|PMID:9861014
Biological Process	GO:0044242	cellular lipid catabolic process	Acadl	IMP		Mouse	MGI:MGI:1321427|PMID:9861014
Biological Process	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	Acadl	IMP		Mouse	MGI:MGI:3526480|PMID:15639194
Biological Process	GO:0033539	fatty acid beta-oxidation using acyl-CoA dehydrogenase	Acadl	IDA		Rat	PMID:3968063|RGD:2317678
Biological Process	GO:0009062	fatty acid catabolic process	Acadl	IMP		Mouse	PMID:21151927
Biological Process	GO:0042758	long-chain fatty acid catabolic process	Acadl	IDA		Rat	PMID:3968063|RGD:2317678
Biological Process	GO:0045717	negative regulation of fatty acid biosynthetic process	Acadl	IMP		Mouse	MGI:MGI:3526480|PMID:15639194
Biological Process	GO:0046322	negative regulation of fatty acid oxidation	Acadl	IMP		Mouse	MGI:MGI:3526480|PMID:15639194
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Acadl	IMP		Mouse	MGI:MGI:1309667|PMID:9802886
Biological Process	GO:0090181	regulation of cholesterol metabolic process	Acadl	IMP		Mouse	MGI:MGI:3526480|PMID:15639194
Biological Process	GO:0009409	response to cold	Acadl	IMP		Mouse	PMID:21151927
Biological Process	GO:0001659	temperature homeostasis	Acadl	IMP		Mouse	MGI:MGI:3526480|PMID:15639194

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern