Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACD
  • Mouse genes Acd
  • Rat genes Acd
  • Zfish genes acd
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Acd

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070182	DNA polymerase binding	ACD	IPI	UniProtKB:O14746	Human	PMID:17237767
Molecular Function	GO:0070182	DNA polymerase binding	ACD	IPI	UniProtKB:O14746	Human	PMID:25172512
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9BSI4	Human	PMID:15181449
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9NUX5	Human	PMID:15181449
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9BSI4-3	Human	PMID:15231715
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9NUX5-2	Human	PMID:15231715
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9BSI4	Human	PMID:15380063
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9BSI4-3	Human	PMID:15383534
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9NUX5	Human	PMID:15383534
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9NUX5	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9BSI4	Human	PMID:16880378
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9NUX5-1	Human	PMID:16880378
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9NUX5	Human	PMID:17237768
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q91WC1	Human	PMID:17632522
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9NUX5-1	Human	PMID:17632522
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9H668	Human	PMID:19648609
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:O00410	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:O43768	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:O75821	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:P07476	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:P31948	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:P49796	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:P62258	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q13885	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q14195	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q8N386	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q96JY6	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9BSI4	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9BTW9	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9BXI6	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9H477	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9NUX5	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9UJU6	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9UNE7	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9Y3A5	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q92900	Human	PMID:21829167
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q8VC56	Human	PMID:22101936
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q91WC1	Human	PMID:22101936
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q2NKJ3	Human	PMID:22763445
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9H668	Human	PMID:22763445
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q93009	Human	PMID:25172512
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9BSI4	Human	PMID:25172512
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9NUX5	Human	PMID:25172512
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9BSI4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9BSI4	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9BSI4	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9NUX5	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9NUX5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9BSI4	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	ACD	IPI	UniProtKB:Q9NUX5	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Acd	IPI	UniProtKB:Q3TNS5|UniProtKB:Q91WC1	Mouse	MGI:MGI:4441256|PMID:17632522
Molecular Function	GO:0005515	protein binding	Acd	IPI	UniProtKB:Q8K2X3	Mouse	MGI:MGI:4441116|PMID:19648609
Molecular Function	GO:0005515	protein binding	Acd	IPI	PR:Q91WC1	Mouse	PMID:17053789
Molecular Function	GO:0005515	protein binding	Acd	IPI	MGI:MGI:1920086	Mouse	PMID:17053789
Molecular Function	GO:0005515	protein binding	acd	IPI	ZFIN:ZDB-GENE-050306-34	Zfish	PMID:21311760
Molecular Function	GO:0005515	protein binding	acd	IPI	ZFIN:ZDB-GENE-030131-6168	Zfish	PMID:21311760
Molecular Function	GO:0005515	protein binding	acd	IPI	ZFIN:ZDB-GENE-110324-1	Zfish	PMID:21311760
Molecular Function	GO:0044877	protein-containing complex binding	ACD	IPI	ComplexPortal:CPX-2129	Human	PMID:25172512
Molecular Function	GO:0042162	telomeric DNA binding	ACD	IDA		Human	PMID:23685356
Molecular Function	GO:0042162	telomeric DNA binding	Acd	IDA		Mouse	MGI:MGI:5500098|PMID:23685356
Molecular Function	GO:0042162	telomeric DNA binding	acd	IDA		Zfish	PMID:21311760
Cellular Component	GO:0000781	chromosome, telomeric region	ACD	IDA		Human	PMID:15380063
Cellular Component	GO:0000781	chromosome, telomeric region	ACD	HDA		Human	PMID:19135898
Cellular Component	GO:0000781	chromosome, telomeric region	ACD	IDA		Human	PMID:23685356
Cellular Component	GO:0000781	chromosome, telomeric region	ACD	IDA		Human	PMID:24270157
Cellular Component	GO:0000781	chromosome, telomeric region	ACD	IDA		Human	PMID:25172512
Cellular Component	GO:0000781	chromosome, telomeric region	Acd	IDA		Mouse	MGI:MGI:5500098|PMID:23685356
Cellular Component	GO:0016604	nuclear body	ACD	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000783	nuclear telomere cap complex	ACD	IDA		Human	PMID:16880378
Cellular Component	GO:0000783	nuclear telomere cap complex	Acd	IDA		Mouse	MGI:MGI:3829120|PMID:18185984
Cellular Component	GO:0070187	shelterin complex	ACD	IPI		Human	PMID:15383534
Cellular Component	GO:0070187	shelterin complex	ACD	IDA		Human	PMID:15383534
Cellular Component	GO:0070187	shelterin complex	ACD	IMP		Human	PMID:21852327
Cellular Component	GO:0070187	shelterin complex	ACD	IDA		Human	PMID:23685356
Biological Process	GO:0007568	aging	acd	IMP	ZFIN:ZDB-GENO-221011-1	Zfish	PMID:35667242
Biological Process	GO:0007568	aging	acd	IMP	ZFIN:ZDB-GENO-221011-2	Zfish	PMID:35667242
Biological Process	GO:0030326	embryonic limb morphogenesis	Acd	IMP	MGI:MGI:1856658	Mouse	PMID:15537664
Biological Process	GO:0070200	establishment of protein localization to telomere	ACD	IMP		Human	PMID:25589350
Biological Process	GO:0007507	heart development	acd	IMP	ZFIN:ZDB-MRPHLNO-110321-5	Zfish	PMID:21311760
Biological Process	GO:0007507	heart development	acd	IMP	ZFIN:ZDB-MRPHLNO-110321-4	Zfish	PMID:21311760
Biological Process	GO:0006886	intracellular protein transport	ACD	IMP		Human	PMID:15181449
Biological Process	GO:0043066	negative regulation of apoptotic process	acd	IMP	ZFIN:ZDB-MRPHLNO-110321-4	Zfish	PMID:21311760
Biological Process	GO:0032211	negative regulation of telomere maintenance via telomerase	ACD	IGI	UniProtKB:Q9NUX5	Human	PMID:15181449
Biological Process	GO:0032211	negative regulation of telomere maintenance via telomerase	ACD	IMP		Human	PMID:15380063
Biological Process	GO:0060381	positive regulation of single-stranded telomeric DNA binding	ACD	IDA		Human	PMID:17237767
Biological Process	GO:0051973	positive regulation of telomerase activity	ACD	IDA		Human	PMID:17237768
Biological Process	GO:0032212	positive regulation of telomere maintenance via telomerase	ACD	IDA		Human	PMID:17237768
Biological Process	GO:0031848	protection from non-homologous end joining at telomere	Acd	IMP		Mouse	MGI:MGI:3829120|PMID:18185984
Biological Process	GO:0070198	protein localization to chromosome, telomeric region	ACD	IDA		Human	PMID:15181449
Biological Process	GO:0070198	protein localization to chromosome, telomeric region	ACD	IMP		Human	PMID:15181449
Biological Process	GO:0035282	segmentation	Acd	IMP	MGI:MGI:1856658	Mouse	PMID:15537664
Biological Process	GO:0001501	skeletal system development	Acd	IMP	MGI:MGI:1856658	Mouse	PMID:15537664
Biological Process	GO:0032202	telomere assembly	ACD	IMP		Human	PMID:16880378
Biological Process	GO:0016233	telomere capping	ACD	IGI	UniProtKB:Q9NUX5	Human	PMID:17632522
Biological Process	GO:0016233	telomere capping	ACD	IDA		Human	PMID:21852327
Biological Process	GO:0016233	telomere capping	ACD	IDA		Human	PMID:25172512
Biological Process	GO:0016233	telomere capping	Acd	IMP		Mouse	MGI:MGI:4441256|PMID:17632522
Biological Process	GO:0000723	telomere maintenance	ACD	IDA		Human	PMID:15181449
Biological Process	GO:0001655	urogenital system development	Acd	IMP	MGI:MGI:1856658	Mouse	PMID:15537664

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern