Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACOT1,ACOT2
  • Mouse genes Acot1
  • Rat genes Acot1
  • Zfish genes acot20,acot21,acot22
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Acot1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	ACOT2	IDA		Human	PMID:10944470
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	ACOT2	IDA		Human	PMID:16940157
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	ACOT1	IDA		Human	PMID:16940157
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	Acot1	IDA		Mouse	PMID:11694534
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	Acot1	IDA		Rat	PMID:7906114|RGD:14390064
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	Acot1	IDA		Rat	PMID:9490035|RGD:70703
Molecular Function	GO:0005515	protein binding	ACOT2	IPI	UniProtKB:Q9NZ94-2	Human	PMID:25464930
Cellular Component	GO:0005829	cytosol	ACOT1	IDA		Human	PMID:16940157
Cellular Component	GO:0005829	cytosol	Acot1	IDA		Rat	PMID:9490035|RGD:70703
Cellular Component	GO:0005739	mitochondrion	ACOT2	IDA		Human	PMID:16940157
Cellular Component	GO:0005739	mitochondrion	Acot1	HDA		Mouse	PMID:18614015
Biological Process	GO:0006637	acyl-CoA metabolic process	ACOT2	IDA		Human	PMID:10944470
Biological Process	GO:0006637	acyl-CoA metabolic process	ACOT2	IDA		Human	PMID:16940157
Biological Process	GO:0006637	acyl-CoA metabolic process	ACOT1	IDA		Human	PMID:16940157
Biological Process	GO:0001676	long-chain fatty acid metabolic process	ACOT2	IDA		Human	PMID:16940157
Biological Process	GO:0001676	long-chain fatty acid metabolic process	ACOT1	IDA		Human	PMID:16940157
Biological Process	GO:0001676	long-chain fatty acid metabolic process	Acot1	IDA		Mouse	PMID:11694534
Biological Process	GO:0001676	long-chain fatty acid metabolic process	Acot1	IDA		Rat	PMID:7906114|RGD:14390064
Biological Process	GO:0010667	negative regulation of cardiac muscle cell apoptotic process	Acot1	IMP		Rat	PMID:23226270|RGD:13831128
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	ACOT2	IDA		Human	PMID:16940157
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	ACOT1	IDA		Human	PMID:16940157

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern