Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACOT8
  • Mouse genes Acot8
  • Rat genes Acot8
  • Zfish genes acot8
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Acot8

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	ACOT8	IDA		Human	PMID:10092594
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	ACOT8	IDA		Human	PMID:15194431
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	Acot8	IDA		Mouse	PMID:11673457
Molecular Function	GO:0047617	acyl-CoA hydrolase activity	Acot8	IDA		Rat	PMID:11785945|RGD:70235
Molecular Function	GO:0033882	choloyl-CoA hydrolase activity	Acot8	IDA		Rat	PMID:11785945|RGD:70235
Molecular Function	GO:0052815	medium-chain acyl-CoA hydrolase activity	ACOT8	IDA		Human	PMID:9153233
Molecular Function	GO:0052815	medium-chain acyl-CoA hydrolase activity	ACOT8	IDA		Human	PMID:9299485
Molecular Function	GO:0016290	palmitoyl-CoA hydrolase activity	ACOT8	IDA		Human	PMID:9299485
Molecular Function	GO:0005515	protein binding	ACOT8	IPI	UniProtKB:P04601	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	ACOT8	IPI	UniProtKB:P50542	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ACOT8	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ACOT8	IPI	UniProtKB:Q04864-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACOT8	IPI	UniProtKB:Q7Z4N8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ACOT8	IPI	UniProtKB:P03406	Human	PMID:9153233
Molecular Function	GO:0005515	protein binding	ACOT8	IPI	UniProtKB:P03406	Human	PMID:9299485
Molecular Function	GO:0005515	protein binding	ACOT8	IPI	UniProtKB:P04601	Human	PMID:9299485
Cellular Component	GO:0005739	mitochondrion	Acot8	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005782	peroxisomal matrix	ACOT8	IDA		Human	PMID:10092594
Cellular Component	GO:0005782	peroxisomal matrix	ACOT8	IMP		Human	PMID:14709540
Cellular Component	GO:0005777	peroxisome	Acot8	IDA		Mouse	MGI:MGI:3693380|PMID:14561759
Cellular Component	GO:0005777	peroxisome	Acot8	IDA		Rat	PMID:11785945|RGD:70235
Biological Process	GO:0006637	acyl-CoA metabolic process	ACOT8	IDA		Human	PMID:9153233
Biological Process	GO:0006637	acyl-CoA metabolic process	ACOT8	IDA		Human	PMID:9299485
Biological Process	GO:0006637	acyl-CoA metabolic process	Acot8	IDA		Mouse	PMID:11673457
Biological Process	GO:0006637	acyl-CoA metabolic process	Acot8	IDA		Rat	PMID:11785945|RGD:70235
Biological Process	GO:0043649	dicarboxylic acid catabolic process	ACOT8	IDA		Human	PMID:16141203
Biological Process	GO:0045225	negative regulation of CD4 production	ACOT8	IDA		Human	PMID:9153233
Biological Process	GO:0016559	peroxisome fission	ACOT8	IDA		Human	PMID:15194431

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern