Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACOX1
  • Mouse genes Acox1
  • Rat genes Acox1
  • Zfish genes acox1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Acox1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003997	acyl-CoA oxidase activity	ACOX1	IMP		Human	PMID:18536048
Molecular Function	GO:0003997	acyl-CoA oxidase activity	ACOX1	IMP		Human	PMID:32169171
Molecular Function	GO:0003997	acyl-CoA oxidase activity	ACOX1	IMP		Human	PMID:7876265
Molecular Function	GO:0003997	acyl-CoA oxidase activity	ACOX1	IDA		Human	PMID:8117268
Molecular Function	GO:0003997	acyl-CoA oxidase activity	Acox1	IDA		Rat	PMID:7462191|RGD:14402446
Molecular Function	GO:0005504	fatty acid binding	Acox1	IDA		Rat	PMID:1400324|RGD:2299949
Molecular Function	GO:0050660	flavin adenine dinucleotide binding	Acox1	IDA		Rat	PMID:11872165|RGD:12793024
Molecular Function	GO:0016401	palmitoyl-CoA oxidase activity	Acox1	IDA		Rat	PMID:1400324|RGD:2299949
Molecular Function	GO:0030165	PDZ domain binding	ACOX1	IDA		Human	PMID:23209302
Molecular Function	GO:0005515	protein binding	ACOX1	IPI	UniProtKB:Q86WA8	Human	PMID:18281296
Molecular Function	GO:0042803	protein homodimerization activity	ACOX1	IDA		Human	PMID:32169171
Molecular Function	GO:0042803	protein homodimerization activity	Acox1	IDA		Rat	PMID:11872165|RGD:12793024
Cellular Component	GO:0005737	cytoplasm	Acox1	IDA		Mouse	PMID:11156684
Cellular Component	GO:0016020	membrane	ACOX1	HDA		Human	PMID:19946888
Cellular Component	GO:0005739	mitochondrion	Acox1	HDA		Mouse	PMID:14651853
Cellular Component	GO:0005778	peroxisomal membrane	Acox1	IDA		Mouse	PMID:12915479
Cellular Component	GO:0005777	peroxisome	ACOX1	IDA		Human	PMID:32169171
Cellular Component	GO:0005777	peroxisome	ACOX1	IDA		Human	PMID:17881773
Cellular Component	GO:0005777	peroxisome	ACOX1	IDA		Human	PMID:7876265
Cellular Component	GO:0005777	peroxisome	ACOX1	IDA		Human	PMID:8117268
Cellular Component	GO:0005777	peroxisome	ACOX1	IDA		Human	PMID:8943006
Cellular Component	GO:0005777	peroxisome	Acox1	IDA		Mouse	MGI:MGI:5319609|PMID:17881773
Cellular Component	GO:0005777	peroxisome	Acox1	IDA		Rat	PMID:11872165|RGD:12793024
Cellular Component	GO:0005777	peroxisome	Acox1	IDA		Rat	PMID:1400324|RGD:2299949
Biological Process	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	ACOX1	IMP		Human	PMID:18536048
Biological Process	GO:0033540	fatty acid beta-oxidation using acyl-CoA oxidase	Acox1	IDA		Rat	PMID:1400324|RGD:2299949
Biological Process	GO:0009062	fatty acid catabolic process	ACOX1	IMP		Human	PMID:32169171
Biological Process	GO:0019395	fatty acid oxidation	ACOX1	IMP		Human	PMID:7876265
Biological Process	GO:0019395	fatty acid oxidation	Acox1	IMP		Mouse	MGI:MGI:4442306|PMID:20195242
Biological Process	GO:0006091	generation of precursor metabolites and energy	ACOX1	IMP		Human	PMID:7876265
Biological Process	GO:0050665	hydrogen peroxide biosynthetic process	ACOX1	IMP		Human	PMID:32169171
Biological Process	GO:0006629	lipid metabolic process	ACOX1	IDA		Human	PMID:8117268
Biological Process	GO:0006693	prostaglandin metabolic process	ACOX1	IMP		Human	PMID:7876265
Biological Process	GO:0007283	spermatogenesis	Acox1	IMP	MGI:MGI:1857811	Mouse	PMID:8798738
Biological Process	GO:0140493	very long-chain fatty acid beta-oxidation	ACOX1	IMP		Human	PMID:32169171
Biological Process	GO:0000038	very long-chain fatty acid metabolic process	ACOX1	IMP		Human	PMID:18536048

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern