Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACP5
  • Mouse genes Acp5
  • Rat genes Acp5
  • Zfish genes acp5a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Acp5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003993	acid phosphatase activity	Acp5	IDA		Mouse	PMID:11168643
Molecular Function	GO:0003993	acid phosphatase activity	Acp5	IDA		Mouse	PMID:9308894
Molecular Function	GO:0003993	acid phosphatase activity	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:8898228
Molecular Function	GO:0003993	acid phosphatase activity	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11731469
Molecular Function	GO:0003993	acid phosphatase activity	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643
Molecular Function	GO:0003993	acid phosphatase activity	Acp5	IDA		Rat	PMID:19854170|RGD:2315877
Molecular Function	GO:0008199	ferric iron binding	ACP5	IDA		Human	PMID:15993892
Molecular Function	GO:0008198	ferrous iron binding	ACP5	IDA		Human	PMID:15993892
Molecular Function	GO:0016787	hydrolase activity	Acp5	IDA		Rat	PMID:11890682|RGD:619585
Cellular Component	GO:0005615	extracellular space	Acp5	IDA		Rat	PMID:20003323|RGD:2315874
Cellular Component	GO:0005764	lysosome	Acp5	IDA		Mouse	PMID:11168643
Cellular Component	GO:0005764	lysosome	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11731469
Biological Process	GO:0060349	bone morphogenesis	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:8898228
Biological Process	GO:0045453	bone resorption	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:8898228
Biological Process	GO:0045453	bone resorption	Acp5	IEP		Rat	PMID:20069278|RGD:2315871
Biological Process	GO:0034224	cellular response to zinc ion starvation	Acp5	IEP		Rat	PMID:21893222|RGD:151667428
Biological Process	GO:0050830	defense response to Gram-positive bacterium	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643
Biological Process	GO:0016311	dephosphorylation	Acp5	IDA		Mouse	PMID:9308894
Biological Process	GO:0032611	interleukin-1 beta production	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643
Biological Process	GO:0032615	interleukin-12 production	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643
Biological Process	GO:0010934	macrophage cytokine production	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643
Biological Process	GO:0033555	multicellular organismal response to stress	Acp5	IEP		Rat	PMID:19113077|RGD:2315906
Biological Process	GO:0007162	negative regulation of cell adhesion	Acp5	IDA		Rat	PMID:19854170|RGD:2315877
Biological Process	GO:0050728	negative regulation of inflammatory response	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643
Biological Process	GO:0032691	negative regulation of interleukin-1 beta production	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643
Biological Process	GO:0032695	negative regulation of interleukin-12 production	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643
Biological Process	GO:0010936	negative regulation of macrophage cytokine production	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643
Biological Process	GO:0045019	negative regulation of nitric oxide biosynthetic process	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643
Biological Process	GO:0032929	negative regulation of superoxide anion generation	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643
Biological Process	GO:0032720	negative regulation of tumor necrosis factor production	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643
Biological Process	GO:0006809	nitric oxide biosynthetic process	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643
Biological Process	GO:0001503	ossification	Acp5	IEP		Rat	PMID:19403161|RGD:2315903
Biological Process	GO:0030316	osteoclast differentiation	Acp5	IEP		Rat	PMID:19361364|RGD:2315902
Biological Process	GO:0030335	positive regulation of cell migration	Acp5	IMP		Rat	PMID:19854170|RGD:2315877
Biological Process	GO:0070723	response to cholesterol	Acp5	IEP		Rat	PMID:19110235|RGD:2315908
Biological Process	GO:0034097	response to cytokine	Acp5	IDA		Mouse	PMID:8200916
Biological Process	GO:0045471	response to ethanol	Acp5	IEP		Rat	PMID:22576626|RGD:151667429
Biological Process	GO:0032868	response to insulin	Acp5	IEP		Rat	PMID:20818503|RGD:151667419
Biological Process	GO:0033591	response to L-ascorbic acid	Acp5	IEP		Rat	PMID:19110235|RGD:2315908
Biological Process	GO:0032496	response to lipopolysaccharide	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643
Biological Process	GO:0036005	response to macrophage colony-stimulating factor	Acp5	IEP		Rat	PMID:7669437|RGD:151665777
Biological Process	GO:0009612	response to mechanical stimulus	Acp5	IEP		Rat	PMID:20833686|RGD:151665823
Biological Process	GO:0014070	response to organic cyclic compound	Acp5	IEP		Rat	PMID:19264158|RGD:2315905
Biological Process	GO:0014070	response to organic cyclic compound	Acp5	IEP		Rat	PMID:20818503|RGD:151667419
Biological Process	GO:0010043	response to zinc ion	Acp5	IEP		Rat	PMID:19369052|RGD:2315901
Biological Process	GO:0042554	superoxide anion generation	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643
Biological Process	GO:0032640	tumor necrosis factor production	Acp5	IMP	MGI:MGI:2180086	Mouse	PMID:11168643

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern