Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACSL3
  • Mouse genes Acsl3
  • Rat genes Acsl3
  • Zfish genes acsl3a,acsl3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Acsl3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0047676	arachidonate-CoA ligase activity	Acsl3	IDA		Rat	PMID:28209804|RGD:14697717
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	ACSL3	IMP		Human	PMID:20219900
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	ACSL3	IMP		Human	PMID:22633490
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	Acsl3	IDA		Rat	PMID:28209804|RGD:14697717
Molecular Function	GO:0004467	long-chain fatty acid-CoA ligase activity	Acsl3	IDA		Rat	PMID:8663269|RGD:70280
Molecular Function	GO:0005515	protein binding	ACSL3	IPI	UniProtKB:P56962	Human	PMID:29549094
Molecular Function	GO:0019904	protein domain specific binding	ACSL3	IPI	UniProtKB:P07948-1	Human	PMID:20605918
Molecular Function	GO:0019904	protein domain specific binding	ACSL3	IPI	UniProtKB:P07948-2	Human	PMID:20605918
Molecular Function	GO:0019901	protein kinase binding	ACSL3	IPI	UniProtKB:P07947	Human	PMID:20605918
Cellular Component	GO:0005783	endoplasmic reticulum	ACSL3	IDA		Human	PMID:14741744
Cellular Component	GO:0005783	endoplasmic reticulum	ACSL3	IDA		Human	PMID:20605918
Cellular Component	GO:0005794	Golgi apparatus	ACSL3	IDA		Human	PMID:20605918
Cellular Component	GO:0005811	lipid droplet	ACSL3	IDA		Human	PMID:14741744
Cellular Component	GO:0005811	lipid droplet	ACSL3	IDA		Human	PMID:21498505
Cellular Component	GO:0016020	membrane	ACSL3	HDA		Human	PMID:19946888
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ACSL3	IDA		Human	PMID:14741744
Cellular Component	GO:0048471	perinuclear region of cytoplasm	ACSL3	IDA		Human	PMID:20605918
Biological Process	GO:0007420	brain development	Acsl3	IEP		Rat	PMID:8663269|RGD:70280
Biological Process	GO:0006633	fatty acid biosynthetic process	Acsl3	IDA		Rat	PMID:8663269|RGD:70280
Biological Process	GO:0044539	long-chain fatty acid import into cell	ACSL3	IDA		Human	PMID:20219900
Biological Process	GO:0001676	long-chain fatty acid metabolic process	ACSL3	IMP		Human	PMID:22633490
Biological Process	GO:0001676	long-chain fatty acid metabolic process	Acsl3	IDA		Rat	PMID:28209804|RGD:14697717
Biological Process	GO:0042998	positive regulation of Golgi to plasma membrane protein transport	ACSL3	IMP		Human	PMID:20605918
Biological Process	GO:2001247	positive regulation of phosphatidylcholine biosynthetic process	ACSL3	IMP		Human	PMID:18003621
Biological Process	GO:0051047	positive regulation of secretion	ACSL3	IMP		Human	PMID:18003621
Biological Process	GO:0007584	response to nutrient	Acsl3	IEP		Rat	PMID:16772660|RGD:1599807
Biological Process	GO:0014070	response to organic cyclic compound	Acsl3	IEP		Rat	PMID:19025659|RGD:2312804
Biological Process	GO:0034379	very-low-density lipoprotein particle assembly	ACSL3	IMP		Human	PMID:18003621

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern