Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACTL6A
  • Mouse genes Actl6a
  • Rat genes Actl6a
  • Zfish genes actl6a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Actl6a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Actl6a	IDA		Mouse	PMID:9845365
Molecular Function	GO:0031492	nucleosomal DNA binding	ACTL6A	HDA		Human	PMID:16217013
Molecular Function	GO:0005515	protein binding	ACTL6A	IPI	UniProtKB:P25490	Human	PMID:18026119
Molecular Function	GO:0005515	protein binding	ACTL6A	IPI	UniProtKB:P25490	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	ACTL6A	IPI	UniProtKB:Q92785	Human	PMID:28533407
Molecular Function	GO:0005515	protein binding	ACTL6A	IPI	UniProtKB:P51532	Human	PMID:28649782
Molecular Function	GO:0005515	protein binding	ACTL6A	IPI	UniProtKB:P25490	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	Actl6a	IPI	UniProtKB:Q9D8M7	Mouse	MGI:MGI:3775125|PMID:17640523
Cellular Component	GO:0000785	chromatin	ACTL6A	HDA		Human	PMID:16217013
Cellular Component	GO:0031011	Ino80 complex	ACTL6A	IDA		Human	PMID:21303910
Cellular Component	GO:0031011	Ino80 complex	ACTL6A	IDA		Human	PMID:18026119
Cellular Component	GO:0071564	npBAF complex	ACTL6A	IDA		Human	PMID:18816825
Cellular Component	GO:0071564	npBAF complex	Actl6a	IDA		Mouse	MGI:MGI:3775125|PMID:17640523
Cellular Component	GO:0071564	npBAF complex	Actl6a	IDA		Mouse	PMID:23785148
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	ACTL6A	IDA		Human	PMID:27153538
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	ACTL6A	IDA		Human	PMID:10966108
Cellular Component	GO:0035267	NuA4 histone acetyltransferase complex	ACTL6A	IDA		Human	PMID:14966270
Cellular Component	GO:0005654	nucleoplasm	ACTL6A	IDA		Human	GO_REF:0000052
Cellular Component	GO:0000786	nucleosome	ACTL6A	IDA		Human	PMID:27153538
Cellular Component	GO:0005634	nucleus	ACTL6A	IDA		Human	PMID:18026119
Cellular Component	GO:0005634	nucleus	Actl6a	IDA		Mouse	PMID:12437990
Cellular Component	GO:0005886	plasma membrane	ACTL6A	IDA		Human	GO_REF:0000054
Cellular Component	GO:0032991	protein-containing complex	ACTL6A	HDA		Human	PMID:16217013
Cellular Component	GO:0016514	SWI/SNF complex	ACTL6A	IDA		Human	PMID:11078522
Cellular Component	GO:0016514	SWI/SNF complex	ACTL6A	IDA		Human	PMID:29374058
Cellular Component	GO:0016514	SWI/SNF complex	ACTL6A	IDA		Human	PMID:8804307
Cellular Component	GO:0016514	SWI/SNF complex	ACTL6A	IDA		Human	PMID:8895581
Cellular Component	GO:0016514	SWI/SNF complex	Actl6a	IDA		Mouse	MGI:MGI:6157116|PMID:29374058
Cellular Component	GO:0070603	SWI/SNF superfamily-type complex	Actl6a	IDA		Mouse	PMID:24335282
Biological Process	GO:0001825	blastocyst formation	Actl6a	IMP		Mouse	PMID:27869233
Biological Process	GO:0006338	chromatin remodeling	ACTL6A	IDA		Human	PMID:11726552
Biological Process	GO:0006338	chromatin remodeling	ACTL6A	HDA		Human	PMID:16217013
Biological Process	GO:0006338	chromatin remodeling	ACTL6A	IDA		Human	PMID:21303910
Biological Process	GO:0006338	chromatin remodeling	Actl6a	IDA		Mouse	PMID:9845365
Biological Process	GO:0043968	histone H2A acetylation	ACTL6A	IDA		Human	PMID:27153538
Biological Process	GO:0043967	histone H4 acetylation	ACTL6A	IDA		Human	PMID:27153538
Biological Process	GO:0007399	nervous system development	Actl6a	IMP		Mouse	MGI:MGI:3775125|PMID:17640523
Biological Process	GO:0003407	neural retina development	ACTL6A	IEP		Human	PMID:18816825
Biological Process	GO:0045739	positive regulation of DNA repair	Actl6a	IDA		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ACTL6A	IMP		Human	PMID:27641337
Biological Process	GO:1905168	positive regulation of double-strand break repair via homologous recombination	ACTL6A	IDA		Human	PMID:27153538
Biological Process	GO:1904507	positive regulation of telomere maintenance in response to DNA damage	Actl6a	IMP		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0051726	regulation of cell cycle	ACTL6A	IMP		Human	PMID:26340092
Biological Process	GO:0051726	regulation of cell cycle	ACTL6A	IMP		Human	PMID:27153538
Biological Process	GO:0033044	regulation of chromosome organization	ACTL6A	IMP		Human	PMID:26340092
Biological Process	GO:0006282	regulation of DNA repair	Actl6a	IDA		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0006275	regulation of DNA replication	ACTL6A	IMP		Human	PMID:25016522
Biological Process	GO:0060382	regulation of DNA strand elongation	ACTL6A	IMP		Human	PMID:25016522
Biological Process	GO:0045995	regulation of embryonic development	Actl6a	IMP		Mouse	MGI:MGI:5638510|PMID:23979016
Biological Process	GO:0021510	spinal cord development	Actl6a	IEP		Rat	PMID:23677776|RGD:9587760
Biological Process	GO:0000723	telomere maintenance	Actl6a	IMP		Mouse	MGI:MGI:5638510|PMID:23979016

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern