Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ACTL7A
  • Mouse genes Actl7a
  • Rat genes Actl7a
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Actl7a

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ACTL7A	IPI	UniProtKB:Q9UGI8	Human	PMID:21278383
Molecular Function	GO:0005515	protein binding	ACTL7A	IPI	UniProtKB:Q8TC94	Human	PMID:33626338
Molecular Function	GO:0005515	protein binding	Actl7a	IPI	RGD:1566346	Rat	PMID:21278383|RGD:7247437
Cellular Component	GO:0001669	acrosomal vesicle	ACTL7A	IDA		Human	PMID:32923619
Cellular Component	GO:0001669	acrosomal vesicle	Actl7a	IMP		Mouse	MGI:MGI:5285134|PMID:21278383
Cellular Component	GO:0005737	cytoplasm	Actl7a	IDA		Mouse	MGI:MGI:5285134|PMID:21278383
Cellular Component	GO:0005794	Golgi apparatus	Actl7a	IDA		Mouse	MGI:MGI:5285134|PMID:21278383
Cellular Component	GO:0001673	male germ cell nucleus	Actl7a	IDA		Mouse	PMID:12672658
Cellular Component	GO:0031514	motile cilium	Actl7a	IDA		Mouse	PMID:12672658
Cellular Component	GO:0005634	nucleus	ACTL7A	HDA		Human	PMID:21630459
Cellular Component	GO:0032991	protein-containing complex	ACTL7A	IDA		Human	PMID:21278383
Cellular Component	GO:0032991	protein-containing complex	Actl7a	IDA		Rat	PMID:21278383|RGD:7247437
Biological Process	GO:0001675	acrosome assembly	Actl7a	IMP		Mouse	MGI:MGI:6790748|PMID:32923619
Biological Process	GO:0009566	fertilization	Actl7a	IMP		Mouse	MGI:MGI:6790748|PMID:32923619

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern