Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADAM15
  • Mouse genes Adam15
  • Rat genes Adam15
  • Zfish genes adam15
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adam15

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005178	integrin binding	ADAM15	IMP		Human	PMID:22505472
Molecular Function	GO:0008237	metallopeptidase activity	ADAM15	IDA		Human	PMID:12777399
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q99962	Human	PMID:10531379
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q9UKS6	Human	PMID:10531379
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q9Y5X1	Human	PMID:10531379
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P06239	Human	PMID:11741929
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P06241	Human	PMID:11741929
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P08631	Human	PMID:11741929
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P12931	Human	PMID:11741929
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P62993	Human	PMID:11741929
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q5HYK7-4	Human	PMID:15280379
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q5HYK7-5	Human	PMID:15280379
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:O15259	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P06241	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P07948	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P08631	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P12931	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P62993	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q5TCZ1	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q8WV41	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q9UKS6	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q9Y5X1	Human	PMID:16374509
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P37198	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q02446	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q13643	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q8N9N5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q93062	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:O15259	Human	PMID:25825872
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P06239	Human	PMID:25825872
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P07948	Human	PMID:25825872
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P08631	Human	PMID:25825872
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P12931	Human	PMID:25825872
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:P62993	Human	PMID:25825872
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q06187	Human	PMID:25825872
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q5TCZ1	Human	PMID:25825872
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q8WV41	Human	PMID:25825872
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q92882	Human	PMID:25825872
Molecular Function	GO:0005515	protein binding	ADAM15	IPI	UniProtKB:Q9Y5X1	Human	PMID:25825872
Molecular Function	GO:0005515	protein binding	Adam15	IPI	UniProtKB:Q99962|UniProtKB:Q9Y5X1	Mouse	MGI:MGI:3687666|PMID:10531379
Molecular Function	GO:0017124	SH3 domain binding	ADAM15	IPI	UniProtKB:Q99962	Human	PMID:10531379
Molecular Function	GO:0017124	SH3 domain binding	ADAM15	IPI	UniProtKB:Q9Y5X1	Human	PMID:10531379
Cellular Component	GO:0009986	cell surface	ADAM15	IDA		Human	PMID:22505472
Cellular Component	GO:0070062	extracellular exosome	ADAM15	IDA		Human	PMID:22505472
Cellular Component	GO:0005615	extracellular space	Adam15	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Biological Process	GO:0060317	cardiac epithelial to mesenchymal transition	Adam15	IMP		Mouse	PMID:19156209
Biological Process	GO:1904628	cellular response to phorbol 13-acetate 12-myristate	ADAM15	IDA		Human	PMID:22505472
Biological Process	GO:0002418	immune response to tumor cell	ADAM15	IDA		Human	PMID:22505472
Biological Process	GO:0045087	innate immune response	ADAM15	IDA		Human	PMID:22505472
Biological Process	GO:0007229	integrin-mediated signaling pathway	ADAM15	IMP		Human	PMID:22505472
Biological Process	GO:0008584	male gonad development	Adam15	IEP		Rat	PMID:12815633|RGD:10047128
Biological Process	GO:0030308	negative regulation of cell growth	ADAM15	IMP		Human	PMID:22505472
Biological Process	GO:0030336	negative regulation of cell migration	ADAM15	IMP		Human	PMID:22505472
Biological Process	GO:0001953	negative regulation of cell-matrix adhesion	ADAM15	IMP		Human	PMID:22505472
Biological Process	GO:1900121	negative regulation of receptor binding	ADAM15	IMP		Human	PMID:22505472
Biological Process	GO:1990910	response to hypobaric hypoxia	Adam15	IEP		Rat	PMID:22230263|RGD:13703065
Biological Process	GO:0042246	tissue regeneration	Adam15	IEP		Rat	PMID:11102971|RGD:632016

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern