Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ADAM22
  • Mouse genes Adam22
  • Rat genes Adam22
  • Zfish genes adam22
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Adam22

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	ADAM22	IPI	UniProtKB:P63104	Human	PMID:12589811
Molecular Function	GO:0005515	protein binding	ADAM22	IPI	UniProtKB:O95970	Human	PMID:20463223
Molecular Function	GO:0005515	protein binding	ADAM22	IPI	UniProtKB:Q9BZR6	Human	PMID:20463223
Molecular Function	GO:0005515	protein binding	ADAM22	IPI	UniProtKB:Q14160	Human	PMID:24550280
Molecular Function	GO:0005515	protein binding	ADAM22	IPI	UniProtKB:O95970|UniProtKB:P78352	Human	PMID:27066583
Molecular Function	GO:0005515	protein binding	ADAM22	IPI	UniProtKB:Q14160	Human	PMID:30126976
Molecular Function	GO:0005515	protein binding	Adam22	IPI	UniProtKB:Q9JIA1	Mouse	MGI:MGI:4365335|PMID:18974846
Molecular Function	GO:0005515	protein binding	Adam22	IPI	UniProtKB:Q9R1V4	Mouse	MGI:MGI:5695673|PMID:26269648
Molecular Function	GO:0005515	protein binding	Adam22	IPI	UniProtKB:Q8K4Y5	Mouse	MGI:MGI:3663801|PMID:16990550
Molecular Function	GO:0005515	protein binding	Adam22	IPI	UniProtKB:Q9CPW0	Mouse	PMID:25707359
Molecular Function	GO:0005515	protein binding	Adam22	IPI	PR:Q8K1S1	Mouse	PMID:21068328
Molecular Function	GO:0005515	protein binding	Adam22	IPI	PR:Q8K1S1	Mouse	PMID:20220021
Cellular Component	GO:0030424	axon	Adam22	IDA		Mouse	MGI:MGI:4436790|PMID:20089912
Cellular Component	GO:0043194	axon initial segment	Adam22	IDA		Rat	PMID:30598502|RGD:153298976
Cellular Component	GO:0098978	glutamatergic synapse	Adam22	IPI		Mouse	PMID:20133599
Cellular Component	GO:0098978	glutamatergic synapse	Adam22	IDA		Mouse	PMID:20133599
Cellular Component	GO:0098978	glutamatergic synapse	Adam22	IDA		Mouse	PMID:16990550
Cellular Component	GO:0098978	glutamatergic synapse	Adam22	IPI		Mouse	PMID:16990550
Cellular Component	GO:0098978	glutamatergic synapse	Adam22	IMP		Mouse	PMID:16990550
Cellular Component	GO:0016020	membrane	Adam22	IDA		Mouse	MGI:MGI:4436790|PMID:20089912
Cellular Component	GO:0005886	plasma membrane	ADAM22	IDA		Human	PMID:27066583
Cellular Component	GO:0098839	postsynaptic density membrane	Adam22	IPI		Mouse	PMID:20133599
Cellular Component	GO:0098839	postsynaptic density membrane	Adam22	IDA		Mouse	PMID:20133599
Cellular Component	GO:0098839	postsynaptic density membrane	Adam22	IDA		Mouse	PMID:16990550
Cellular Component	GO:0098839	postsynaptic density membrane	Adam22	IMP		Mouse	PMID:16990550
Cellular Component	GO:0098839	postsynaptic density membrane	Adam22	IPI		Mouse	PMID:16990550
Biological Process	GO:0008344	adult locomotory behavior	Adam22	IMP	MGI:MGI:3584137	Mouse	PMID:15876356
Biological Process	GO:0042063	gliogenesis	Adam22	IGI	MGI:MGI:2180197	Mouse	PMID:21068328
Biological Process	GO:0022011	myelination in peripheral nervous system	Adam22	IMP	MGI:MGI:3584137	Mouse	PMID:15876356
Biological Process	GO:0022011	myelination in peripheral nervous system	Adam22	IMP	MGI:MGI:3584137	Mouse	PMID:20220021
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Adam22	IMP		Mouse	PMID:16990550
Biological Process	GO:0099645	neurotransmitter receptor localization to postsynaptic specialization membrane	Adam22	IDA		Mouse	PMID:16990550
Biological Process	GO:1903829	positive regulation of protein localization	Adam22	IMP		Rat	PMID:30598502|RGD:153298976
Biological Process	GO:0014037	Schwann cell differentiation	Adam22	IMP	MGI:MGI:3584137	Mouse	PMID:15876356

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern